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|
770
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754
| 1,000
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scientific publication
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"Clinical and Molecular Techniques for Diagnosis and Monitoring of Prostatic Cancer C. S. FOSTER, MD, PHD, MRCPatH, AND P. D. ABEL, CuM FRCS Part2 of this ymposiam reviews of prostate in prostatic biopsy specimens and has evaluated the cancer apd other than conventional computer-based image systems currenly avai that rely either on specialized inscrumen- able for analyzing prostate cancer. That clearly The majority of such techniques already have been ad- puters for morphometric analysis with an evaluation of dressed opies inthis However, methods currently uvalable, with ther prob Contributions to the averall understanding of For exauiple, ifs image analysis system Consideration of features, crunpredictable nature, then the expense ofa dedicated ceed tt compauble software programs able To un on come mercially available appears to be the TISSUE MORPHOMETRY sisted. acquisition of morphometric data is laborious, these various aspects of prostae measurements of tumor volume provides an en- examined, Although hanced assessment of the of individual oF [tom autopsy material! other nave examined volumetric i biopsy Although there ig and have shown these sb to be important of NHK shee parler. her poten and ee ay prostatic resection, the ratiu of prostatic chippings con- P this approach shoal be adopted with cautious ining cancer to the wal number of chippings removed of the limitations of the numerical data ob- stage and volume.’ Recently, tis technique ta relative areas of cancer IMAGING TECHNIQUES resected prostatic chippings. x! Image phasiced the value of camputer-issisted morphometry Magnetic Reserance Imaging coupled with powerful data processing computer soft-etecuon of small and localized malignancies mare have renewed in morphologic provides the best opportunity for cure. To such grading systems and have shown these fo be a more accurate appraisal of te size, location, and extent and, hence, objective of obtaining of the primary disease iy uandatory. In this respect detailed data with which co predict the and cransrectal ultrasound burn prostate cancer In this symposium, (TRUS) of the prostate are approximately 60% accurate Dalton Hiss 1993) has aderessed| OF potentially greater valne magnetic resonance ine a ‘ar and Walach provide compelling evidence that while From the Departments of Histopathology and Surgery, Wlagnetic resonance imaging with current levels of res- School, UR, olution’ at 300 ym fapproximately 20 cell st ‘ics one snd repre to provides acceptable images that accurately enable the ‘MD, PhD, MRCPath, Department of Ehstopathology. Roval Post- location of small fesions, further refinement of resolu- Mea tion wll this toward the level of Up 1992 by WB, Sander Compan Furthermore, magoelic resonance a troscopie of issue components nd 305 50628402"
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762
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762
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"ag We mvoce a - alls City _ ae ag 193, 5 Com & Company — 1427420 Louisville gun Be | eee SUSE (902) 5007375 DATE: October 5, 1979 = eae a ge. 3 Brown ee 2 L 4600 W, Hil St. | Kentucky 40202 aos | Glenda SO Hyatt | Se we ook “oferta an RENTAL | a “12 | Welt safelock stands 16}00 | 3] 1 -| extra castored stand i £] 1 lanp & | | “| trouperette ITI w/spare lamp az} 1 3/4\" VIR w/monitor on cart a aes 260}00 | 8 x 8 sereen Mike Ro vay i 24100 4 Impedence match box w/cables, mike, . j 71/00 | lel 43/04 | Bie “ORIGINAL | [APPROVED For | 7 jest ql | SEE SEY! [a as mms one ying be ee pn ey Se | uae veer De | the | Pie Sx oe ater PR | RECT oy pare PAR es SEE"
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1,000
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"CC: Stcrling, Carol (LHC); Kendall, Suc (LHC); Williard, JoAn M,",
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"My mail is nOl coopcraling: This is thc sprcadshect with absolule numbcrs",
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"From: Tuckcr; Tonyd (LHC) To;ltlcrann, Palti F CC: Stcrling, Carol (LHC); Kendall, Suc (LHC); Williard, JoAn M, BCC: Primary Date: 4/23/1997 2.16.01 PM Last Modified Date: 1997-Dec-15 08.15.59 Last Touched Date: Sent Date: 1997-Apr-23 13.31.0 Received Datc: 1997-Apr-23 14.16.01 Subject:",
"Attachments: MRIAUDXLS",
"My mail is nOl coopcraling: This is thc sprcadshect with absolule numbcrs",
"MRIAUDXLS 3925 in MRIAUD XLS ]]",
"8 8",
"RJR24041434 70004 1403"
] |
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19,
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115,
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|
|
777
| 1,000
|
news article
|
[
"‘the",
"decision",
"of",
"the",
"Aneriean",
"Heart",
"Association",
"to",
"Join",
"tn",
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"campatene",
"to",
"discourage",
"vas",
"reported",
"in",
"and",
"ty.",
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"wire",
"services.",
"Sone",
"stories",
"a",
"round-up",
"of",
"other",
"recent.",
"affecting",
"the",
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"industry",
"set",
"S",
"TRIBUNE",
"The",
"Words",
"Get",
"YORK",
"nm",
"New",
"York,",
"N.Y.",
"I",
".",
".",
"June",
"9,",
"1963",
"rt",
"Associz",
"eart",
"Association",
"mokm,",
"arnm.",
"few",
"York",
"New",
"York,",
"June",
"9,",
"1963",
"between",
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"smoking",
"shoul",
"be",
"Heart",
"Society",
"Maps:",
"none",
"professions.”",
"Henst",
"Assocation,",
"July,",
"1960.",
"Drive",
"on",
"Cigarettes",
"er",
"do",
"Tiere",
"of",
"the.",
"harmfut",
"effects",
"of",
"cigarette",
"smoking",
"to",
"warrant",
"the",
"By",
"ALFRED",
"F,",
"ue",
"ands",
"and",
"and"
] |
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[
"‘the decision of the Aneriean Heart Association to Join tn educatloral campatene to discourage vas reported in and ty. the wire services. Sone stories a round-up of other recent. affecting the tobacco industry set S TRIBUNE The Words Get YORK nm New York, N.Y. I . . June 9, 1963 rt Associz eart Association mokm, arnm. few York New York, June 9, 1963 between cigarette smoking shoul be Heart Society Maps: none professions.” Henst Assocation, July, 1960. Drive on Cigarettes er do Tiere of the. harmfut effects of cigarette smoking to warrant the By ALFRED F, ue ands and and Amen set Ata ih, Chapter vung with the hee ta rng tb, hee smoking by the general public.” ‘emphasis on teen-agers. (Of attacks and strokes in Heat Asin, ytd. tcc ARG poard of directors An ad hoc committee of fone rm tear eae ae ee her aoe sed Toons ‘against smoking more strongly. Throwing out most of the groups.” The associa. NODS the Heart heath groups The associ’ urged Mat ete ge Mein ae, st ike rt Hae elution by the Association's board of directors meeting ‘The move marks the first More and larger longitudinal ted a aes etn ume utr AES Ja ) Shh Sa patie nan agency, naar, Reportedly, the AHA had been on the verge of launch- ded to wage a public campaign artery and other cartio. ing a public campaign against cigarette smoking following ‘on cone ‘a study in 1960 that showed that smokers are In 50 to 150 ‘A spokesman said that the , Possible of eter Sine at a a Sng rans pen rte ia gue ihe weft stout seareh Commitee sult fate ws a th Come cold Sl ea thas become available which contradicts or invalidates the the heart yesterday myocardial infarction and groupe ion? Officials of the Tobacco Industry Research Committee Jn 3960, the association of duration and in- spokesmen for the industry in the eontroversy— A report indicating that evidenc: censity of smoking on the risk Ses ore One, nd a ory SRS som acted ty and Gisease do not prove board reviews constituents of tobacco men have said in the past: \"Statistics never PE on the heart and blood vesse'= ‘killed anybody. ‘come shice £860, of animals and humans and ov ‘In the case of lung cancer it is usually assumed that Are Cited such disease processes ax ex: cigarette smoke may injure lung tissues, But a biological “No evidence has become perimental wR ‘Explanation for the link between heart ailments and since 2 Studien of patients tn our oir othe AA 1061 ne $B vn ANA Me on qos Se hoon ey ballets tat sucking Winger the Pe, Sis toe te A ac Hoe Sangeet an eins | to sue a tobacco company for the pert smoking ls Cigar ‘ortaty trom coronary N, Juan Bove ee ean Hints cies) he tune see sump on Wall Say sani Pity New York City Health SHEER, ees op james urged doctors to persuade patlents to stop smoking vessels theparms and legs seph T. Doyle of Albany and He warned that ony ebe of 15 lung cancer is now being saved and said: “If you (doctors! can that 0 Pre Tr on Cues Fu sea ter ee rst"
] |
[
[
55,
78,
730,
1000
]
] | 9
|
|
1,000
| 754
|
news article
|
[
"DRAFT",
"AJS/ em",
"3/24/81",
"Proposed Response",
"Press",
"and",
"Other",
"Inquiries Regarding Publication by",
"the",
"Laboratory",
"FTC",
"FTC",
"Test",
"Results",
"Carbon",
"Yields",
"Monoxide",
"ofCigarettes",
"a7",
"Wih",
"Lorillara",
"the",
"Tobacco",
"statement urging",
"Institute",
"in interpreting",
"caution",
"the",
"significance",
"the Federal",
"Commission baboratory",
"Trade",
"test",
"results",
"carbon monoxide",
"yields of",
"cigarettes",
"ished",
"publ_",
"this",
"week",
"the",
"Commission .",
"Lorillard",
"issuing",
"spokesperson",
"noted",
"that",
"chese",
"test",
"results",
"the",
"FTC",
"nas attempted,",
"without scientific",
"proof",
"to leave",
"the",
"impression",
"that",
"monoxide",
"from",
"carpon",
"cigarette",
"significant",
"smoke",
"represents",
"threat",
"human",
"However ,",
"health.",
"Lorillard # rtodentative pointed",
"Ere",
"out",
"that",
"the",
"relevant scientific literature",
"this regard",
"#t",
"the great",
"of scientific evidence",
"inconclusive",
"and",
"body",
"available",
"indicates",
"thc small",
"the",
"subject",
"that",
"amount",
"monoxide generated",
"carbon",
"by cigarettes",
"an insigni-",
"ficant part of",
"total",
"the",
"carbon",
"monoxide",
"the atmosphere",
"L",
"#4#"
] |
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[
"AJS/ em DRAFT 3/24/81 Proposed Response Press and Other Inquiries Regarding Publication by the FTC FTC Laboratory Test Results Carbon Monoxide Yields ofCigarettes a7 Wih Lorillara the Tobacco Institute statement urging caution in interpreting the significance the Federal Trade Commission baboratory",
"test results",
"carbon monoxide yields of cigarettes",
"publ_ ished this week",
"the Commission .",
"Lorillard",
"issuing chese",
"spokesperson noted that",
"test results the FTC nas attempted, without scientific",
"proof to leave the impression that carpon monoxide from",
"cigarette smoke represents",
"significant threat",
"human",
"health. However , Ere Lorillard # rtodentative pointed out",
"that the relevant scientific literature this regard #t inconclusive and the great body of scientific evidence",
"available",
"the subject indicates that thc small amount",
"carbon monoxide generated by cigarettes",
"an insigni-",
"ficant part of the total carbon monoxide",
"the atmosphere",
"L",
"#4#"
] |
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] | 9
|
|
1,000
| 775
|
specification
|
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"280800",
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[
"(Csizprht)",
"125/95",
"DCort Llcacdn Tobicca corcoration 01/25/35 16131.2J Cicpirite Kinufacturing Spoclf Ications Products Hict Prad Grold 518fC Thru 109 Procuct Cnangc Elctive Grouc Expe Descriptic Wuntar 3673 CiPRi cP Jevilaeextal 93-0025 1/25/85 CAPRI 100 CCeP %12 Viter I2[ Witer Ia/ DcsccIption LenathtDy FILTGR JIRCHISGD 36-0150 Filt Ron CAFRI I0o'5 Wltar cooo 67ii Icnatn Aooooc& 4ccuceegtoca 'ressuro Mectchtg Anchar",
"CIG HaER \"rieary Cigaretto Casio Ci-0108O Tobucco HT-033 4ccottT JIJERC 'IPPINGS \"uorioo sccticn Ierth 76.6\" Acoxno Cut Iength. Lenath JothIn Ghen { Aort - 6444 * Zs0c4 carette crcudferercu entllatIc7 55.04 Tcanccn Vtcr FR-9438 Fonc",
"3-9",
":cRareR} 6-656 6800 FLAX K4 64*3500-35401.P",
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"1-7900 31-0620 20-0220 8I-J261 28-0180 35-030[",
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"8-0818",
"CooCOOO EACH 3-COoCcoo",
"CIG CASE FILL",
"clitd?",
"29-4750 case FLaiK Cfri Plac} C The Case StIckEr I} Brakd DESCR[PTIOVSTYL E 4d The prooict CcQe M1ber",
"HSES",
"I6t5 wis?acers",
"CoOOcOO",
"CASES PER PALLET",
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556,
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] | 7
|
|
782
| 1,000
|
form
|
[
"BY:",
"1-18-94",
"i",
"3:47PM",
"i",
"BERNSTEIN",
"1/",
"3",
"Sanford",
"C.",
"Bernstein",
"&",
"Co.,",
"Inc.",
"e@",
"Facsimile",
"Cover",
"Sheet",
"Seite",
"el",
"Comments:",
"8",
"2",
"N"
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724,
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712,
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[
"BY: 1-18-94 i 3:47PM i BERNSTEIN 1/ 3 Sanford C. Bernstein & Co., Inc. e@ Facsimile Cover Sheet Seite el Comments: 8 2 N"
] |
[
[
21,
8,
744,
935
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] | 1
|
|
1,000
| 772
|
letter
|
[
"Juno 11, 1970",
"Harrlo",
"BouLande",
"Edltor",
"pnerIcan ModIcal_Note",
"535 North_Dearbera 54588t",
"chiccgo.IllinoLe 60610",
"Doar Harv}",
"I bave folloved Ulth Euch Anterodt Yar_Focdet",
"Aeboctatkon",
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"AnarIcan Mur8ob",
"art1c10b0n",
"Cho",
"tb0 NationaL Aeboctation for Proctical",
"ef & c2lont.",
"1ur80 Educaiton and Borvico (NAFHES) .",
"epparent",
"Intent",
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"o[fIckal tovard 1Icenaod",
"beadquartere",
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"bontb: Noenrh4lo; Dobt regardo:",
"BLnceroly,",
"zhn",
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"Enc)",
"Mro . Ropo Hartin",
"bcc $"
] |
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[
155,
783,
275,
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],
[
119,
785,
151,
801
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] |
[
"Juno 11, 1970",
"Harrlo BouLande Edltor pnerIcan ModIcal_Note 535 North_Dearbera 54588t chiccgo.IllinoLe 60610",
"Doar Harv} I bave folloved Ulth Euch Anterodt Yar_Focdet art1c10b0n Cho AnarIcan Mur8ob Aeboctatkon bacaudo ef & c2lont. tb0 NationaL Aeboctation for Proctical 1ur80 Educaiton and Borvico (NAFHES) . Lank ewaro Df Eho attItodo and epparent Intent cortaln AA beadquartere o[fIckal tovard 1Icenaod practIcal Dur*94 tbe Board O[ DLrectord Q5 Faeics adoptad e101ficunt statedodl Iau Dontbe 480. a0 enclouing Copy OI 4t {or joua Tbo offIcere and dlroctor\" OI Lartcs bavo often Yondorod Luy certata AXA] Pooplo bate sOch Ebort - Dochted Atditude cancerasns Ticonaee praceicel 7t8ed* 44 mou thare Jerione bbertate Of boeb EZle end LPNa tbroughout tha country:} Tboro I% DP denyAng tho [act that thero Lo urgentpoed and placo [or Doeb Ebe baltb caro tenr FII, HAPKE8 10 Bon-proflt_oreantratton that # dovotad antArely t0 tho {leld %f Cracticatod peorta 10'0 {Lno ercan-eatton 6ta 5any dodieatod '49is 1ty eotabL Lahod Eba {Lrat coreditlng carvLco Tor mureLng tbat 10 today OITL - an5;ececo51 059838:*04t368 Focoealeod Dy_tho o5 Educatlon. I bopo t0 200 Jou dt tbe NMA Eootlng Loter thLo bontb: Noenrh4lo; Dobt regardo: BLnceroly,",
"Loonard &' zhn",
"LszAe Enc) bcc $ Mro . Ropo Hartin"
] |
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] | 0
|
|
762
| 1,000
|
memo
|
[
"septenber",
"17,",
"1988",
"MEMORANDUM",
"TO",
"FILE:",
"The",
"following",
"are",
"my",
"comments",
"and",
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"in",
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"and",
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"its",
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"of",
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"-",
".",
"the",
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"trend",
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"and",
".",
"the",
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"and",
"sales",
"organizations",
"have",
"been",
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"and",
"strengthened",
"(particularly",
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"the",
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"in-store",
"activity",
"required",
"due",
"to",
"greater",
"competitive",
"price",
"and",
"promotional",
"activities)",
".",
"export",
"units",
"have"
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[
"septenber 17, 1988 MEMORANDUM TO FILE: The following are my comments and observations comparing The Anerican Tobacco Company to the Liggett Group. in the last year and one-half, The American Tobacco Company has made extraordinary strides forward that strengthenea its prospects for continuing its long record of increasing profits - . the sales trend has significantiy improved, with the first half of 1988 showing an increase in units and . the marketing and sales organizations have been increased and strengthened (particularly important with the increased in-store activity required due to greater competitive price and promotional activities) . export units have moved well above the 1 billion annual ea Durham factory was closed with a major reduction in very successful new products have been launched: BALL MALE Rel Filters and LIGHTS"
] |
[
[
85,
167,
602,
710
]
] | 15
|
|
777
| 1,000
|
invoice
|
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[
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[
[
46,
151,
758,
910
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] | 11
|
|
1,000
| 777
|
budget
|
[
"B-192",
"MUNTHLY",
"REPORT",
"PROJECT",
"No .",
"STATUS",
"MANACEMCNT",
"Of Nicotine",
"Migration",
"(MIGON",
"PROJECT TITLE:",
"DATE :",
"7/30/78",
"829",
"615",
"DUDGET",
"FROJECT DESCRIPTION:",
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"Tlc",
"Vrinci)",
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"(act YC\"",
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"onirclyC",
"OEOiCCt",
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"rulti",
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"AIROt'",
"Hd VaF[ [IA",
"7i\"\"",
"7tmts",
"otht",
"Weci",
"nrA",
"Iralaeto",
"I! Vni#",
"CIl #",
"MAALION",
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"Wl\"\"",
"T",
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"Jls.",
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"Jed#",
"104nIn,",
"FLc .",
"Mlc",
"\"MHcF",
"L",
"claczel#",
"lcvecu",
"Yili",
"alue",
"Tivi",
"ML4IAT",
"Jid",
"rumuclc",
"dcLCrMine",
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"L7,in",
"@Gn",
"Hlia",
"UOli",
"Tuct\"cniyc",
"({uai",
"uer",
"cxtnjclnm",
"Wicidi]",
"OLa(JCLUrfM",
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"MUttc",
"lolccu",
"Lt(Cl",
"ercollicut",
"YEARAZL78",
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"1",
"30",
"24",
"1",
"W",
"COM PONEnts",
"PROJECT",
"Huran",
"Euyi",
"neteniLC",
"IIC| Q1",
"ciu<",
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"Tal",
"Jlcuei",
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"Lrans [7t",
"Ael Cu",
"Budgeted",
"758",
"1,100",
"Total",
"Hrs",
"Date",
"826",
"Hrs",
"made",
"usinc",
"two experimental",
"RL",
"Larson",
"has been",
"written",
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"on",
"Smoking",
"55:45",
"results",
"ratio",
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"nicotine",
"lamina",
"and",
"stem:",
"ttgh",
"included",
"leaf analyses",
"blend",
"are",
"taste panel results",
"the",
"and",
"preference",
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"for",
"experimental",
"RL",
"the",
"was",
"treated",
"citric",
"with",
"migrated",
"nicotine",
"filter paper",
"available",
"70 8",
"Up",
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"acid",
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"from",
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"the",
"stoicometric relationship is readily apparent with",
"these",
"and",
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"No",
"additives",
"LAlmina",
"Ireland",
"Sue",
"Sosnarn"
] |
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33
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[
"B-192",
"STATUS REPORT PROJECT No . MUNTHLY MANACEMCNT Migration Of Nicotine (MIGON PROJECT TITLE: DATE : 7/30/78 DUDGET 829 615 FROJECT DESCRIPTION: Vrinci) Taicel (act YC\" Tlc J\"gima onirclyC Uis OEOiCCt rulti Wucl Oeliiui /0 WMAlio\" AIROt' Lrom Hd VaF[ [IA Iralaeto 7i\"\" 7tmts otht Weci nrA W Ei\" Wl\"\" T Sdi I! Vni# CIl # MAALION Mlc weiv \"MHcF Jls. L (1in4\" Jed# 104nIn, FLc . Yili alue Tivi ML4IAT claczel# lcvecu Tnch L7,in @Gn Hlia Jid rumuclc dcLCrMine ({uai uer cxtnjclnm UOli Tuct\"cniyc Wicidi] Lt(Cl delerinfic MUttc OLa(JCLUrfM Jfter lolccu ercollicut",
"YEARAZL78 MONTH",
"1",
"30",
"24",
"1 W",
"PROJECT COM PONEnts Huran",
"Euyi",
"neteniLC IIC| Q1 ciu< MAiul OMLIEL",
"Tal",
"Jlcuei tnr Ael Cu Lrans [7t",
"1,100 Total Hrs Budgeted",
"758",
"Date",
"826 Hrs",
"has been written on two experimental RL made Larson usinc A report lamina and stem: lamina ratio of 55:45 Smoking nicotine results ttgh taste panel results and leaf analyses the blend are included preference was noted for the experimental RL 70 8 available nicotine migrated filter paper treated with citric Up acid from filter paper treated with nicotine alkaloid: Tartaric acid produced migration nicotine alkaloid the acid treated paper No stoicometric relationship is readily apparent with these and other additives LAlmina Sue Ireland Sosnarn"
] |
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file folder
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754
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[
"5 2 MT ion 2 House Democrats Offer a Compromise on Tobacco Regulati ‘By PHILIP ta na agency denn tout: vo ‘me Rosse props er Jay 26 — Two on OM nas wing 1 cis Tr eld pA EDA equi Cr DA are tes ne eu fom ee fn ceguaton of tobaceo, > have enaless ag nat” sd ote Peel ee 08 ves ecto la ere ie dca rei: go wig eae at ton weld en terror Tay nner ent tBu en ta ine Sent materi tis month, the agency as- Food and Drea, asserted ‘One guaranice in thd proposal is an addictive drug and regu. Polilcally dangerous question of power if the som ute ty 4 Ne see arama ey North Carolina Democeat who has debate comes as une Justice. Chacon and every tO cue cave nat ae resentative Ron Wyden of Oregon’ Dany executives lied to Congress or —— — Ro, en of se remand 0 me une revises Ha waa ena ana ae oe etic more a yearto he Deprtment| ew a 2h der chore re pring one lela sat from adverusing in e way intended} that the. was doce. iets | wat are ary oy st ye ested FT al a Re fear thatthe tobacco companies wil | could use the treat of sch ‘Wyden sad today that he | rake concessions satay ett a | iy\" ay | wae om Fite tobacco, “That's what Keeps the | Proposal the right thing in this proposal,” he |. study by the White House, wi | 6 2 by te tiated Set mang ‘Administration could avold nasty | marketing of Het ver would be done to Rose said the tobacco industry | ting che most effective messages many te] malorky in ina, single, am ‘here are licking their chops for that | » ‘one. They want to go head-to-head Some elements of the campaign s ea Nonetheless, Mr. Rose said that} chines and improving enforcement g “while both sides might have trouble } Gf laws that bar sales to minors. It 8 ‘with his plan, it would be worthwhile } would also include educational cam- g i es mapa stow eat] le so, tt and the tobacco from adversing to be et"
] |
[
[
18,
85,
701,
898
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] | 9
|
|
762
| 1,000
|
memo
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[
"DEA THE Memorandum AMERICAN TOBACCO, COMPANY, we Mr. E. C. Wortham oye 9/17/92 tn Glock, Leaf services Nenager ond’ purley strips ~ 1992 & 1992 erope of serine ko. 6379 grades ray nave Ene potential fer in ou ™~ ge 0211872"
] |
[
[
138,
37,
668,
871
]
] | 15
|
|
754
| 1,000
|
email
|
[
"From:",
"Cole,",
"Ron",
"W.",
"To:",
"Ainsworth,",
"W.E.",
"(Gene);",
"Alan",
"Calhoun;",
"Anne",
"Miller;",
"Barbara",
"Goho;",
"Beverly",
"Paszkowski;",
"Brenda",
"Matthews;",
"Bryan",
"Snipes;",
"Carole",
"Crosslin;",
"Carolyn",
"Brinkley;",
"‘Christopher",
"Garland;",
"Darryl",
"Marsch;",
"David",
"Howard;",
"David",
"Powers;",
"Delise",
"LeBlanc;",
"Denise",
"Santos;",
"Dianne",
"Neal;",
"Donald",
"Foreman;",
"Ellen",
"Merritt;",
"Frank",
"Lester;",
"Frank",
"Skinner;",
"Geni",
"Coulter;",
"Glenda",
"Evans;",
"Glenda",
"Goodman;",
"Guy",
"Blynn;",
"H.",
"Bert",
"Gomez;",
"Harvey",
"Freeman;",
"Henry",
"Stokes;",
"Jackie",
"Hemric;",
"Jan",
"Fulton",
"Smith:",
"Jean",
"Lowstetter;",
"Jerry",
"MacFarland;",
"Joan",
"Rutledge;",
"Joc",
"Murray;",
"John",
"Fish;",
"John",
"Singleton;",
"Joseph",
"Coffey;",
"Joyce",
"Muench;",
"Judy",
"Albert;",
"Judy",
"Dobbs;",
"Karen",
"Baker;",
"Keith",
"Kolischak;",
"Kevin",
"Richardson;",
"Lynn",
"Hutchens;",
"M.",
"Hurst",
"Marshall;",
"Mary",
"Hampton;",
"Maura"
] |
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[
"From: Cole, Ron W. To: Ainsworth, W.E. (Gene); Alan Calhoun; Anne Miller; Barbara Goho; Beverly Paszkowski; Brenda Matthews; Bryan Snipes; Carole Crosslin; Carolyn Brinkley; ‘Christopher Garland; Darryl Marsch; David Howard; David Powers; Delise LeBlanc; Denise Santos; Dianne Neal; Donald Foreman; Ellen Merritt; Frank Lester; Frank Skinner; Geni Coulter; Glenda Evans; Glenda Goodman; Guy Blynn; H. Bert Gomez; Harvey Freeman; Henry Stokes; Jackie Hemric; Jan Fulton Smith: Jean Lowstetter; Jerry MacFarland; Joan Rutledge; Joc Murray; John Fish; John Singleton; Joseph Coffey; Joyce Muench; Judy Albert; Judy Dobbs; Karen Baker; Keith Kolischak; Kevin Richardson; Lynn Hutchens; M. Hurst Marshall; Mary Hampton; Maura Payne; Michael Suggs; Mike Phillips; Murray Jones; Nelson, Byron (WKA); Patricia Lawrence; Patricia Mabe; Peter Schmidt; Phyllis Rumple; R. Keith; Randy Tompson; Richard Williams: Rogene Smith; Roger Mozingo; Seth Moskowitz; Sharon Reid; Sheryl Spainhour; Shirley Miller; Steve Strawsburg; Teresa Wood; Timothy Fields; Timothy Swoope; Tommy Payne; Vickie Parrish; Vicky Pierce; Vivian Tumer; William Cook cc: BCC; Primary Date: 12/3/1999 11:25:31 AM Last Modified Date: 1999-Dec-03 11:25:33 Last Touched Date: Sent Date: 1999-Dec-03 11:25:31 Received Date: 1999-Dec-03 11:25:31 Subject: State Government Relations Weekly Status - 12/02/99 Attachments: SGRw991202.DOC 8 8 & & 2 RJR0000001531090253 ° 70029 3568"
] |
[
[
0,
86,
706,
981
]
] | 2
|
|
754
| 1,000
|
resume
|
[
"PRINCIPLE",
"INVESTIGATOR:",
"Reuben",
"Eisenstein,",
"M.D.",
"Date",
"of",
"Birth:",
"May",
"3,",
"1929",
"EDUGATION:",
"Tulane",
"University,",
"B.S.,",
"1949,",
"Biology",
"State",
"University,",
"M.D.,",
"1953,",
"Medicine",
"Me,",
"Sinai",
"Hospital,",
"New",
"York,",
"1954,",
"Intera",
"Presbyterian-St.",
"Luke's",
"Hospital,",
"Chicago,",
"1957-60,",
"Pathology",
"Resident",
"Professional",
"Experience:",
"Assistant",
"Attending",
"to",
"Attending",
"Pathologist,",
"Presbyterian-St.",
"Hospital,",
"Chicago,",
"IL,",
"1960-75;",
"Assistant",
"Professor",
"to",
"Professor",
"of",
"Pathology,",
"University",
"of",
"Iilinois",
"Medical",
"School,",
"1960-69;",
"Professor",
"of",
"Pathology,",
"Rush",
"Medical",
"Colles",
"1971-73;",
"Dizeczor",
"of",
"Cytopathology,",
"and",
"Surgical",
"Pathology,",
"Presbyterian~St.",
"Luke's",
"Hospita",
"1965-70;",
"Dizector",
"of",
"Special",
"Pathology,",
"Luke's",
"Hospital,",
"1970-75;",
"Professe",
"of",
"Pathology,",
"Northwestern.",
"University-Medical",
"School,",
"1975-80;",
"arcending",
"Pathologist,",
"Menorial",
"Hospital,",
"1975-80;",
"Director",
"of",
"Chemistry,",
"Immunology,"
] |
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[
"PRINCIPLE INVESTIGATOR: Reuben Eisenstein, M.D. Date of Birth: May 3, 1929 EDUGATION: Tulane University, B.S., 1949, Biology State University, M.D., 1953, Medicine Me, Sinai Hospital, New York, 1954, Intera Presbyterian-St. Luke's Hospital, Chicago, 1957-60, Pathology Resident Professional Experience: Assistant Attending to Attending Pathologist, Presbyterian-St. Hospital, Chicago, IL, 1960-75; Assistant Professor to Professor of Pathology, University of Iilinois Medical School, 1960-69; Professor of Pathology, Rush Medical Colles 1971-73; Dizeczor of Cytopathology, and Surgical Pathology, Presbyterian~St. Luke's Hospita 1965-70; Dizector of Special Pathology, Luke's Hospital, 1970-75; Professe of Pathology, Northwestern. University-Medical School, 1975-80; arcending Pathologist, Menorial Hospital, 1975-80; Director of Chemistry, Immunology, and Serology, Worthvestern Hospital, 1975-76; Director of Leboratories, VA Lakeside Hospizal, 1576-80; Chief, of Pathology and Laboratory Medicine, Mount Sinai Medical Center and Departnent of Pathology, University of 1980-present. Board of Pathology (Anatomic 1959; Clinical 1964). ere.: Menber, B. Stuéy Section, 1967-71; Consul~ fst, Procter and Company, 1973-751 Ad Hoc NELI, 1975, 1979; Medical Advisory Board, Leukenta Foundation, Inc., 1978-present; Editorial Board, Arterdosclerosis, 1980-present; Visiting Professor, several universities, 1965-present. 94 + : B., ayer, Papjiannis, S., Hess, and Ellis, H.: Mineral bindin; by arterial elastic tissue. Lab. Invest., 13:1198, 1964. : 2. E., Eisenstein, R., Sky-Peck, and HéDonald, J.B.: Electron microscopy \" tritiated thymidine in graduation of malignancy of human bladder carcinomas. Te. Am, Assoc. 56:31, 1964, 3. Eisenstein, R., Rosato, J. and Wied, G.: DNA and protein in hypertrophi: human hearts. Proc. Soc. Exp. Biol. Med., 1332176, 1970. 4. Eisenstein, R-, Soble, and Kuettner, K.E.: Lysozyme in epiphyseal cartilage. TI. The effects of on mouse enbryonic cartilage in organ culture. An. J. Path., 60:43, 1970. Eisenstein, R., Arsenis, C. and Kuettner, K.: Electron microscopic studies of carti— Jage matrix using lysozyme as a vital stain. J. Cell Biol.» 46626, 1970. 6. Eisenstein, BR.» Scott, R.A. end Lesak, A.: Altered Lipid binding by mineralized elastin. Arch. Path,, 92:301, 1971. 7. Eisenstein, R., Sorgente, N. and Kuettner, K.E.: Organization of extra-cellular natr of epiphyseal growth plate. Aner. J. Path., 65:515, 1972. 8, Eisenstein, Re, S., Sorgente, N. and Kuettner, K.E.: Collegen-proteoglycan relationships in epiphyseal cartilage. Am. J. 732443, 1973. 3 Eisenstein, R., Sorgente, N., Soble, L., Miller, A, and Kuettner, The resis~ tance of certain tissues to An. J. Path., 73:765, 1973. NO. Sorgence, N., Kuettner, K.E-, Soble, LW. and Eisenstein, The of tain tissues to invasion. Ii. Evidence for extractable factors in cartilage which davasion by vasewlarized nasenchyne. Lab. Invest., 32:217, 1975. 50186844"
] |
[
[
16,
52,
735,
997
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] | 14
|
|
754
| 1,000
|
letter
|
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[
"LIMITED a OF wer” 27 1970 fir Stouort < a dy Ane 1 House any ter, bene Dye ben 1 longen we fone Hence utd tap Ny bore kit | Tho repuite of the METRE study on the retationenip vetvaen — | and in the united : bo avellable to be used i fn the of | Tho in thu origlnel study covering other i ond bohine the vidi | Gnd of lobe date ney vail prove i toy will to sono extent she for initiating thie study, providing ste cute Se ff end even of the report i fo Intivonce tne end informed epinion hee Seen viviges e oF erguntestione, end in the 1 felt tho right vee for ne, efter vith er Inporiel end taking setount of the vious of tho Tost. Uorking Party, to put proposing a eouree af ection with an vg ef Connitees vith copies te 811 those ved, Provided tho prosossle are 1, ae nenber of the Interin Office, thet the’ progrenne fy proposeie ere based on tho folloving i 1 That uhon the METRA study 48 completed end the report | St uill be of gooe and of interact to export opinion. t 2 Unide At te cloer thet the METRE conclusion thet there Le No in tho Ur | Greenditure ond toral and Failing & tho wsdl Be able fo S| to euch snd to doteties conte"
] |
[
[
220,
35,
725,
713
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|
|
777
| 1,000
|
presentation
|
[
"¥)30",
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[
"¥)30 JOHN MURPHY CLOSING REMARKS PHILIP MORRIS'S GROWTH OVER THE PAST SEVERAL YEARS IS WELL KNOWN. WE HAVE NOT GOTTEN WERE WE ARE TODAY BY BEING COMPLACENT, BUT RATHER BY STRIVING TO BE BEST AT WHAT WE KNOW BEST. YOU'VE HEARD QUITE A BIT ABOUT OUR BUSINESSES HERE TODAY. LET ME COMMENT ON SOME OF THE UNDERLYING TRENDS AND SUMMARIZE OUR CURRENT POSITION. FIRST LET'S TAKE A LOOK AT THE U.S. CIGARETTE INDUSTRY. RECENT VOLUME GROWTH HAS BEEN LACKING. WE ARE ALSO CONCERNED WITH THE 6URDEN OF EXCISE TAXES, MARKETING RESTRICTIONS, RESTRICTIONS ON SMOKING, THE SMOKING AND HEALTH CONTROVERSY AND LITIGATION. x 3 x racy + 3"
] |
[
[
145,
83,
703,
855
]
] | 12
|
|
763
| 1,000
|
resume
|
[
"|",
"pis",
"fo",
"Le:",
"ce",
"fi",
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"|",
"oe",
"|",
"me",
"OLE",
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"i",
"2",
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"Ry",
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"Bed",
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"/",
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"8",
".",
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[
"| pis fo Le: ce fi oe | oe | me OLE Ba Be 4 vitae : 4 ae i 2 afl ee bes He Ry Anerson BOs st a Bed hee Book, are os / i eR ‘ “a oe ae: per ee g 3 8 . Pal a PRE ay bee id LP"
] |
[
[
14,
3,
757,
967
]
] | 14
|
|
754
| 1,000
|
letter
|
[
"whk",
"Sorvor",
"8/26/80",
"12:86",
"PAGE",
"Rightrak",
"a.",
"Tobacco",
"Company,",
"Me",
"we",
"age",
"a",
"BRANCH",
"LAW",
"FIRM",
"anc",
"esis",
"ATTORNEYS",
"AND",
"COUNSELORS",
"AT",
"LAW",
"Y",
"a",
"“nee",
"Gok",
"Coit”",
"2005",
"Re",
"WW",
"set",
"pe",
"‘August",
"25,",
"1999",
".",
"Blizabeth",
"C,",
"David,",
"Esquire",
"‘Legalgard",
"Information",
"Solutions",
"617",
"John",
"F",
"Kennedy",
"Blvd",
"x",
"Suite",
"700",
"Philadelphia,",
"PA",
"19103",
"Re.",
"Litigation",
"Dear",
"Ma.",
"Davi,",
"nclosed,",
"please",
"find",
"our",
"responses",
"to",
"your",
"letter",
"of",
"August",
"3,",
"1999",
"in",
"connection",
"with",
"the",
"Tobacco",
"Litigation.",
"Although",
"this",
"is",
"not",
"a",
"complete",
"list,",
"I",
"assure",
"you",
"that",
"I",
"am",
"diligently",
"working",
"in",
"order",
"to",
"get",
"you",
"all",
"of"
] |
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"whk Sorvor 8/26/80 12:86 PAGE Rightrak a. Tobacco Company, Me we age a BRANCH LAW FIRM anc esis ATTORNEYS AND COUNSELORS AT LAW Y a “nee Gok Coit” 2005 Re WW set pe ‘August 25, 1999 . Blizabeth C, David, Esquire ‘Legalgard Information Solutions 617 John F Kennedy Blvd x Suite 700 Philadelphia, PA 19103 Re. Litigation Dear Ma. Davi, nclosed, please find our responses to your letter of August 3, 1999 in connection with the Tobacco Litigation. Although this is not a complete list, I assure you that I am diligently working in order to get you all of the requested. In order for you to complete your audit, I will send the additional information as soon as possible. ‘Thank you for your patience and please feel free to call me if you have additional questions concerning this matter. Sincerely, Kil Parte * “Laurel Keestler Bookkeeper co: Jed Bergman, Eequire cos oe OF = SS z 3"
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1,000
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"\"clion; thc IFR fusion",
"micchanisu",
"prolein",
"Fwllic Ilcaltl Scrvice",
"Girnml;",
"bupnorlt&",
"JcGative protein that complexcs with Fos",
"cilectvc",
"DuIMMML",
"UaKalatal",
"lunitle",
"Cirmn",
"32in",
"(e-ng",
"IONA binding: #clivity- Ju addition,",
"#IIc] reversiblt",
"imniituts IS",
"408u'",
"4HU:'",
"UaC",
"Eaniceanaran_Amn",
"Cant Moll FSn Glo-",
"cell clones that slably express the IFF prolelo exhibit",
"Myela (Juicolors",
"neinecd",
"Goela",
"puwicalion",
"want by thc payiuchl",
"ailiclt #ert",
"ucitalco",
"cliaigs",
"phasc from",
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"Froxth ATrestcd &lulc",
"uuced CamaCIL",
"arlicle tusl tnciclone",
"hcrony nuirkoFaducelist !ch (",
"Aaceuroamge",
"rosult thal",
"consislent",
"witn",
"in thc",
"uuscnCC",
"ealracen",
"Ceclion ]734 &lchy",
"Indicntt",
"the hypothesis that AF]",
"Joranal ccll",
"cyclc",
"IIIIiciriatL",
"Felltw",
"Itt Nalional Iuclitulcf",
"Hcalih and nripicng",
"METHII",
"74-V219",
"pruprt#SIuI",
"Fcllow _",
"thc Ancricnn Cancer Socicly:",
"chimeras bclwccn",
"steroid",
"Whilc",
"Mmtecr",
"ticonne",
"215-726-2889.",
"T tom cotcemandcnccehould",
"WldtetRL",
"415724.36",
"C;l, clurocor-",
"TAHedar Mnacd AroA\"",
"Actmnr #retm",
"becco'& modilied Kaglcie wc-dium; FHS, Icta",
"Fovine #crun; ]*, thyroid",
"#TI ; wild ty \"c; rCipalyuctasc",
"Wiculdrceuigr KK",
"Ualncenecelant",
"rolit oic ecid receptor,",
"HIMKM, Iuk:",
"dreaciol CATchlorennuhonicnl Acoretrenalcrasn",
"horJlOIIC Tccenior_KAK",
"11502",
"PUBLICATIONS",
"0050408"
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Fos And IKI rendil, arneehntorutinicr omncxtR Onc #pproach for crcating inducible system lucuse : prisingly, the formntion Fos:II heterodimers; plucing te uctivity o protcin under Ihe control ofthc lieatd - #osRInC IFI Fnn] cclimcie troren-inarundcn, uding dumAI sleroid Wanlomo rectuior Ruch Howcvcr, Eel shift ASSAYR clcarly dcmonstrate that I)NA hincing AFI sitcs hy Fos:I)ER hctcrodimcrs IKI Elucocorlicoid receplor (GJ) (hc CstIOgch rereptor (KKA St - homodimcra cAtrogon-dopondena.Mor Ovcr, Ihcal- FCI hsimi urolems HaVC [icl crealed wilh proteins GcnCO cetroecn Inc nhi wrotcin un cflectivc inhil Such os FIA (4), c-Myc (54 the CCAATenhancer-binding \"f Fosaliuded transuclivudict, this fIfect i6 (61, Myol) (7), 053 (8L, and c-Fos (9, J0la cach LHced roicreco thc #rcscnce ul ceirolem Qur Teauils Iudi - Cheds the fusiou pratein HACiunto be' devoid biological M thc IEI pratein dircct, ormono-rovcre- pcliv Mncia eXpr\"ssed in cellz in thc ahscnco Hgrmnan ible inhibitor of Fos and that estrogen etrols tne con- Akcrae iu appropriate wild Vyn (W\") functioni was reclored ditione uneilirc 0 dounAn ncgativc nctivitice UEI in thc prctcncc harugn thc level INA binding Fi ? 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Hawevcr, ncither the Melien LMc' Jun and For familics of on oproleins Are tho Cna Tulerachons ncucmi IEK and W' Jun nor Elrone CLCCWE COI[OLCIIL ~ of the dimeric U ausc!iplion Inctor \"cti- interactions hctwccn IER and Fos are rCgulaled Vv (stroccn; F prateit- (AF'T)\" Thc thrcc mucnut no Fut Fetc corLTasL, IINA binding by HER homodimcrs FERFos elcrodincn- complctcly stropen-dependent_ ccauc thi& novel micchanisu \"clion; thc IFR fusion prolein bupnorlt& Fwllic Ilcaltl Scrvice Girnml; UaKalatal lunitle Cirmn cilectvc DuIMMML JcGative protein that complexcs with Fos 32in (e-ng 4HU:' 408u' UaC Eaniceanaran_Amn Cant Moll FSn Glo- #IIc] reversiblt imniituts IS IONA binding: #clivity- Ju addition, Myela (Juicolors neinecd Goela puwicalion cell clones that slably express the IFF prolelo exhibit ailiclt #ert ucitalco want by thc payiuchl cliaigs uuced CamaCIL Gucr phasc from Froxth ATrestcd &lulc arlicle tusl tnciclone hcrony nuirkoFaducelist !ch ( Aaceuroamge in thc uuscnCC ealracen rosult thal consislent witn Ceclion ]734 &lchy Indicntt METHII the hypothesis that AF] IIIIiciriatL Joranal ccll cyclc Felltw Itt Nalional Iuclitulcf Hcalih and nripicng 74-V219 pruprt#SIuI Fcllow _ thc Ancricnn Cancer Socicly: Whilc Mmtecr ticonne chimeras bclwccn steroid T tom cotcemandcnccehould WldtetRL 215-726-2889. 415724.36 TAHedar Mnacd AroA\" Actmnr #retm C;l, clurocor- Wiculdrceuigr KK Ualncenecelant #TI ; wild ty \"c; rCipalyuctasc becco'& modilied Kaglcie wc-dium; FHS, Icta Fovine #crun; ]*, thyroid dreaciol CATchlorennuhonicnl Acoretrenalcrasn HIMKM, Iuk: horJlOIIC Tccenior_KAK rolit oic ecid receptor,",
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689,
655
]
] | 3
|
|
1,000
| 777
|
presentation
|
[
"American Medical Association",
"Physicians dedicated t0 Lhe heallh of Americz",
"News Release",
"FOR",
"IMHEDIATE RELEASE",
"For",
"further",
"inforoat ion ,",
"Linda",
"Cotsen,",
"contacta",
"312/464-4443",
"Fingland",
"202/245-7163",
"HITHDRAHAL",
"\"OLD JOE",
"CAMEL",
"ADS",
"URGED",
"AMA _",
"0.$",
"SURGEON",
"GENERAL",
"MASBINGTON,",
"March",
"ican",
"Medical",
"The",
"Amer",
"Asgociation",
"and",
"United",
"States",
"Surgeon",
"General",
"Novello,",
"MPE , today",
"Antonia",
"called",
"for",
"the",
"voluntary",
"R.J_",
"Reynolds",
"advertising",
"remoua",
"Tobacco Company of",
"al1",
"using",
"che",
"Old",
"Joe",
"Cane [",
"cigarettes",
"character",
"to pronote",
"Novello urged all",
"The",
"AMA",
"retail",
"cigarette",
"outlets",
"cemove",
"promot",
"onal",
"materials",
"ing",
"the ca",
"fcom stores",
"toon",
"also",
"charactor",
"They",
"asked",
"Dagazines",
"and",
"neuspapers",
"billboard compan",
"Camel",
"ads with",
"refuse",
"the",
"O1d",
"format",
"Camel",
"Joe",
"Studies",
"ished",
"the Joucnal",
"publ",
"the",
"Medical",
"American",
"4350c44t40n",
"(JAHA)",
"last",
"December",
"Old",
"reported",
"that",
"Joe",
"recogni",
"ion",
"factor",
"among",
"six-year-olds",
"of the Disney",
"equal",
"their",
"Identification",
"4ag",
"Hickey",
"1o90",
"Channel",
"House",
"related",
"tudy shoved",
"that",
"advertiging",
"Lobaccc",
"ins",
"promores",
"anc",
"Maint ?",
"nicot ine",
"addiction",
"children",
"amono",
"1dolescents",
"\"R.J. Reynolds",
"4ing",
"aoverta",
"and",
"Cancl cigarettes",
"prOmot ion of",
"has",
"been",
"targeting chfldren.",
"James",
"must",
"sEoP ,",
"Todd",
"vicc",
"R2ad",
"exccutive",
"ident",
"the",
"Reynolds",
"tempt",
"icism",
"Prer",
"ArA -",
"R.J",
"halt",
"releasIng",
"series of",
"ads",
"egedly",
"designed",
"ney",
"dissuade",
"chfldhood",
"disingenuous",
"and",
"snokers",
"smoke",
"gcreen",
"1",
"mores",
"615 North Stalc Surert",
"Chiato,",
"Ilnois 64510",
"312464440"
] |
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[
"American Medical Association Physicians dedicated t0 Lhe heallh of Americz",
"News Release",
"FOR IMHEDIATE RELEASE",
"For further inforoat ion , contacta",
"Linda Cotsen, 312/464-4443 Fingland 202/245-7163",
"HITHDRAHAL \"OLD JOE CAMEL ADS URGED AMA _ 0.$ SURGEON GENERAL",
"MASBINGTON, March The Amer ican Medical Asgociation and United States Surgeon General Antonia Novello, MPE , today called for the voluntary remoua R.J_ Reynolds Tobacco Company of al1 advertising using che Old Joe Cane [ character to pronote cigarettes",
"The AMA Novello urged all retail cigarette outlets cemove promot onal materials ing the ca toon charactor fcom stores They also asked Dagazines neuspapers and billboard compan refuse Camel ads with the O1d Joe Camel format",
"Studies publ ished the Joucnal the American Medical 4350c44t40n (JAHA) last December reported that Old Joe recogni ion factor among six-year-olds 4ag equal their Identification of the Disney Channel Hickey House 1o90 related tudy shoved that Lobaccc advertiging promores anc Maint ? ins nicot ine addiction amono children 1dolescents",
"\"R.J. Reynolds aoverta 4ing and prOmot ion of Cancl cigarettes has been targeting chfldren. must sEoP , R2ad James Todd exccutive vicc Prer ident the ArA - R.J Reynolds tempt halt icism releasIng ney series of ads egedly designed dissuade chfldhood snokers disingenuous and smoke gcreen",
"1 Chiato, 615 North Stalc Surert 312464440 Ilnois 64510",
"mores"
] |
[
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70,
514,
113
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[
384,
836,
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844
]
] | 12
|
|
754
| 1,000
|
budget
|
[
"New",
"Tobacco",
"Association",
"1999",
"Budget",
"State",
"Activities",
"Division",
"($000)",
"Cost",
"Center",
"1400",
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"-",
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"Space",
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"of",
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"Tobacco",
"Institute",
"$37",
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"offices.",
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"leases",
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"New",
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"Association",
"field",
"90",
"offices.",
"(1,500",
"s/f",
"@",
"$20",
"x",
"3)",
"3127"
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[
"New Tobacco Association 1999 Budget State Activities Division ($000) Cost Center 1400 Account 4300 Rent - Office Space 1999 portion of lease obligations for six Tobacco Institute $37 field offices. Office leases for three New Tobacco Association field 90 offices. (1,500 s/f @ $20 x 3) 3127"
] |
[
[
71,
153,
595,
470
]
] | 10
|
|
754
| 1,000
|
specification
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[
260,
331,
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290,
331,
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340,
331,
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338
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376,
331,
393,
338
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402,
331,
424,
338
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[
556,
331,
585,
338
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593,
331,
621,
337
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[
86,
358,
110,
365
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[
230,
363,
232,
365
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241,
358,
271,
365
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278,
358,
290,
365
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[
297,
358,
370,
365
],
[
377,
358,
400,
364
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408,
358,
443,
364
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451,
357,
499,
364
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507,
357,
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364
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[
544,
357,
586,
364
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[
230,
374,
232,
378
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[
241,
372,
253,
378
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[
334,
372,
351,
378
],
[
359,
371,
412,
378
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[
395,
398,
419,
406
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[
507,
398,
529,
405
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[
537,
398,
555,
405
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[
667,
398,
690,
405
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[
377,
412,
419,
419
],
[
86,
439,
129,
446
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[
136,
439,
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446
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[
230,
444,
232,
446
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241,
439,
289,
446
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297,
439,
339,
446
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[
469,
439,
487,
446
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86,
466,
110,
473
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230,
469,
232,
471
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241,
467,
289,
474
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[
297,
467,
338,
474
],
[
353,
467,
394,
473
],
[
402,
466,
437,
473
],
[
445,
466,
461,
473
],
[
469,
466,
487,
473
],
[
500,
466,
549,
473
],
[
86,
493,
108,
500
],
[
117,
493,
154,
500
],
[
162,
496,
165,
498
],
[
173,
494,
196,
500
],
[
280,
496,
282,
498
],
[
291,
493,
327,
500
],
[
334,
493,
382,
500
],
[
389,
493,
419,
500
],
[
427,
493,
462,
500
],
[
469,
493,
512,
500
],
[
519,
493,
536,
500
],
[
86,
534,
141,
542
],
[
432,
534,
456,
541
],
[
230,
567,
232,
569
],
[
261,
562,
283,
569
],
[
291,
562,
307,
569
],
[
315,
561,
345,
569
],
[
352,
561,
369,
569
],
[
377,
562,
394,
569
],
[
401,
561,
438,
569
],
[
241,
575,
271,
583
],
[
372,
575,
388,
582
],
[
371,
603,
388,
610
],
[
395,
602,
413,
610
],
[
254,
713,
271,
720
],
[
278,
713,
307,
720
]
] |
[
"LUXURY CR LTS) REGULAR Beans cone cucanerte woe ere 15.6 kop | \"25.00 Tonacco nop ve ve Tb. we 20 racer “Boe PAPER UPs MIITE TOL CER) XE 256K2 LASER PERF. REPLACE MITH TEAM X MITE TOL CCR) LASER PERT. uur + REFER TO ENGINEERINGS GLUE ROLLER VARIABLE PARTS CATALOG | SY AND CIGARETTE. TYRE TPR. CUT Size TIPPING TIPPING ADHESIVE + NATIONAL 32-2087 ev sean + NATIONAL 52-2100 CPROTOS 100/HK 10) EVA. 61-490- 570. FILLER © PADK = 18.60% VIRGINIA SLIME LIGHTS REGULAR Fr CHOAREYTE FLAX + sac FoR PRINT OTE AND EXPORT cute CRE DHE REF SAP CROSS REFERENCE 9: FILTER: 070198 contenrs PAPER REFLECTS CORE REDUCTION Wo PERF TAGS. EASON FOR «TRG PAPER UPDATED TO A PRESSURE DROP ci, a FS U/ 3 1 To REDUOE DILY AVG TO Ter. RENOVED, DEPLETED. MO TO DC CIGTS. = peanrane Date PREPARATION DATE SUPERCEDES SPECIFICATION 4/01/97"
] |
[
[
79,
140,
701,
954
]
] | 7
|
|
762
| 1,000
|
memo
|
[
"a>",
"Qos",
"(2)",
"J.W,",
"Dorygard",
"i",
"xt.",
"pues",
"peo",
"Sty",
"2050",
"=",
"sates",
"voluce",
"of",
"6,751",
"xeprosents",
"on",
"average",
"204.4",
"million",
"per",
"gay",
"ao",
"1867,",
"or",
"an",
"|",
"Gherenve",
"of",
"202%",
"i",
"average",
"and",
"the",
"parcent",
"change",
"MUSIC",
"hae",
"nonin",
"of",
"Lau",
"cmtained",
"28",
"Sige",
"wich",
"the",
"caye",
"over",
"29",
"bolas",
"a",
"and",
"32",
"Gaye",
"sith",
"the",
"ays",
"20",
"being",
"=",
"october",
"1909",
"1068",
"GT",
"Bayo)",
"i",
"aug",
"Dolly",
"to",
"Brand",
"Ya.",
"1907",
"i",
"as",
"se",
"ee.",
"wa",
"ke",
"re",
"aD",
"as",
"=",
"3",
"ae",
"as",
"re",
"you",
"xo",
"Fitter",
"wee",
"+",
"2",
"Boon",
"ay.",
"2",
"o>",
"st",
"so",
"0?"
] |
[
[
289,
187,
321,
202
],
[
458,
185,
536,
204
],
[
271,
220,
286,
229
],
[
202,
243,
225,
250
],
[
232,
241,
275,
251
],
[
146,
262,
151,
274
],
[
202,
294,
225,
302
],
[
232,
294,
270,
301
],
[
331,
278,
355,
311
],
[
252,
304,
267,
312
],
[
276,
303,
300,
310
],
[
141,
313,
158,
326
],
[
221,
361,
251,
368
],
[
257,
359,
294,
368
],
[
301,
359,
314,
367
],
[
319,
359,
348,
368
],
[
404,
360,
464,
368
],
[
471,
361,
482,
366
],
[
489,
361,
531,
368
],
[
338,
371,
367,
378
],
[
373,
371,
416,
378
],
[
422,
373,
441,
380
],
[
446,
371,
465,
380
],
[
471,
371,
489,
378
],
[
544,
370,
571,
379
],
[
580,
371,
597,
378
],
[
604,
372,
616,
378
],
[
660,
368,
661,
376
],
[
160,
384,
209,
392
],
[
215,
384,
227,
392
],
[
234,
384,
262,
392
],
[
660,
381,
661,
389
],
[
307,
408,
350,
415
],
[
447,
406,
464,
413
],
[
471,
406,
489,
413
],
[
495,
407,
537,
415
],
[
543,
405,
579,
415
],
[
160,
419,
203,
429
],
[
210,
419,
227,
427
],
[
300,
418,
331,
425
],
[
338,
418,
350,
425
],
[
447,
417,
470,
425
],
[
476,
417,
531,
425
],
[
537,
417,
549,
425
],
[
159,
431,
184,
440
],
[
189,
431,
215,
439
],
[
222,
431,
240,
438
],
[
245,
430,
270,
439
],
[
276,
431,
301,
437
],
[
307,
430,
319,
437
],
[
325,
429,
356,
438
],
[
362,
431,
368,
437
],
[
489,
429,
507,
436
],
[
277,
441,
288,
449
],
[
344,
441,
367,
450
],
[
373,
440,
398,
448
],
[
404,
441,
422,
448
],
[
428,
441,
452,
449
],
[
489,
441,
501,
448
],
[
506,
440,
537,
449
],
[
543,
442,
549,
448
],
[
313,
464,
356,
474
],
[
363,
464,
385,
471
],
[
549,
464,
567,
470
],
[
303,
475,
319,
484
],
[
367,
475,
396,
484
],
[
659,
480,
660,
485
],
[
282,
488,
305,
496
],
[
313,
487,
344,
496
],
[
659,
486,
678,
493
],
[
151,
490,
191,
517
],
[
543,
498,
559,
505
],
[
567,
498,
591,
505
],
[
659,
496,
660,
499
],
[
209,
535,
221,
542
],
[
228,
535,
241,
542
],
[
302,
533,
318,
541
],
[
484,
533,
507,
540
],
[
568,
532,
585,
540
],
[
209,
546,
221,
553
],
[
227,
546,
240,
553
],
[
301,
548,
319,
550
],
[
380,
559,
416,
561
],
[
677,
553,
681,
556
],
[
302,
568,
326,
575
],
[
484,
567,
508,
575
],
[
659,
564,
675,
585
],
[
160,
592,
185,
599
],
[
191,
592,
203,
599
],
[
210,
591,
246,
599
],
[
297,
590,
324,
597
],
[
549,
591,
555,
596
],
[
675,
587,
679,
595
],
[
160,
603,
185,
611
],
[
490,
601,
507,
609
],
[
549,
605,
555,
606
],
[
308,
613,
326,
620
],
[
393,
616,
416,
618
],
[
490,
612,
507,
620
],
[
549,
615,
585,
618
]
] |
[
"a> Qos (2) J.W, Dorygard i xt. pues peo Sty 2050 = sates voluce of 6,751 xeprosents on average 204.4 million per gay ao 1867, or an | Gherenve of 202% i average and the parcent change MUSIC hae nonin of Lau cmtained 28 Sige wich the caye over 29 bolas a and 32 Gaye sith the ays 20 being = october 1909 1068 GT Bayo) i aug Dolly to Brand Ya. 1907 i as se ee. wa ke re aD as = 3 ae as re you xo Fitter wee + 2 Boon ay. 2 o> st so 0? he uns Vasa . 28.0 + 3.0 i sane wa toed ene ro Fitter 327 ao Su 3 aS Se 2 TT ale “ALL 28 ~ 2 252.5 soe + 58 17 mae run nice uss Tatas oe eine (QUALITY OF THE FILMED. 3 10"
] |
[
[
28,
185,
681,
909
]
] | 15
|
|
778
| 1,000
|
questionnaire
|
[
"RESULTS",
"|",
".",
"|",
"|",
"t",
"|",
"a",
"g",
"|",
"5",
"3",
"|",
".",
"8",
"|",
"3",
"|",
"Be"
] |
[
[
363,
454,
415,
466
],
[
0,
508,
2,
526
],
[
617,
501,
619,
503
],
[
0,
529,
2,
538
],
[
1,
619,
2,
626
],
[
1,
705,
2,
717
],
[
1,
721,
2,
728
],
[
740,
783,
750,
791
],
[
739,
792,
749,
800
],
[
0,
803,
2,
812
],
[
738,
801,
748,
809
],
[
737,
810,
747,
819
],
[
1,
820,
2,
825
],
[
602,
820,
608,
823
],
[
736,
820,
746,
827
],
[
0,
848,
3,
879
],
[
732,
847,
743,
862
],
[
0,
961,
1,
969
],
[
0,
980,
655,
1000
]
] |
[
"RESULTS | . | | t | a g | 5 3 | . 8 | 3 | Be"
] |
[
[
0,
454,
750,
1000
]
] | 13
|
|
762
| 1,000
|
memo
|
[
"BROWN",
"f&",
"WILLIAMSON",
"TOBACCO",
"CORPORATION",
"RESEARCH",
"&",
"DEVELOPMENT",
"THTERNAL",
"Tor.",
"B.",
"A.",
"Reasor",
"ce:",
"A.",
"H.",
"L.",
"Reynolds",
"B.",
"A.",
"Kerr",
"AL",
"3.",
"Golub",
"H.C.",
"Woerte",
"A.",
"P.",
"L.",
"Chen.",
"A.",
"Goodman",
"DATE:",
"November",
"2,",
"1990",
"SUBJECT:",
"DUPONE",
"RESULTS",
"FOR",
"MENTHOL",
"PERCEPTION",
"BELATR",
"LTS",
"-",
"RIGH/313",
"DETAILS",
"Attached",
"are",
"Monadic",
"Attribute",
"and",
"analytical",
"results,",
"The",
"following",
"products",
"were",
"evaluated:",
"313080",
"~",
"0.65%",
"MENTHOL/CONTROL.",
"313081",
"—",
"0.75%",
"MENTHOL",
"313082",
"~",
"0.82%",
"MENTHOL",
"313083",
"-",
"0.91%",
"MENTEOL",
"313084",
"~",
"1.00%",
"MENTHOL",
"Monadic",
"Attribute",
"ratings",
"were",
"made",
"by",
"54",
"LD-M",
"KS",
"smokers",
"and",
"9",
"PRISM",
"paneliste.",
"‘The",
"Dupont",
"study",
"I.D.s",
"were",
"900253",
"and"
] |
[
[
210,
93,
245,
102
],
[
253,
93,
259,
100
],
[
266,
91,
336,
100
],
[
343,
90,
392,
99
],
[
399,
88,
474,
98
],
[
267,
119,
323,
128
],
[
331,
119,
337,
126
],
[
344,
117,
419,
126
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[
261,
146,
316,
154
],
[
93,
203,
125,
211
],
[
155,
202,
167,
210
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[
176,
201,
189,
210
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[
198,
201,
240,
209
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86,
219,
113,
246
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[
156,
228,
168,
236
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[
156,
242,
168,
250
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[
177,
241,
189,
250
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198,
240,
255,
251
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157,
255,
168,
263
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[
177,
255,
190,
263
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[
199,
255,
227,
263
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[
156,
269,
169,
277
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[
178,
268,
190,
276
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[
199,
267,
234,
276
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157,
282,
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290
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199,
281,
242,
290
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179,
296,
190,
304
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158,
310,
170,
318
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179,
309,
191,
317
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201,
309,
229,
317
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180,
336,
192,
344
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[
201,
335,
251,
344
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[
98,
365,
130,
374
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[
160,
363,
215,
372
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[
224,
362,
236,
373
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[
246,
362,
272,
370
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[
100,
392,
152,
401
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161,
390,
202,
399
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210,
389,
259,
399
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267,
389,
288,
397
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295,
387,
344,
397
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351,
385,
420,
395
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441,
384,
482,
393
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489,
383,
509,
392
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517,
387,
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530,
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586,
390
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100,
434,
147,
444
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101,
460,
155,
470
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163,
462,
182,
468
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190,
459,
240,
468
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248,
457,
311,
467
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319,
456,
339,
464
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[
347,
454,
415,
465
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423,
453,
475,
462
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491,
452,
511,
460
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520,
450,
581,
460
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102,
475,
156,
486
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[
163,
476,
190,
482
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199,
472,
267,
481
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[
235,
499,
276,
508
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284,
503,
291,
504
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299,
497,
333,
506
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340,
495,
444,
505
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236,
512,
276,
521
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285,
516,
291,
517
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299,
511,
334,
519
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341,
509,
389,
519
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236,
526,
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535
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285,
529,
292,
531
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[
300,
524,
334,
533
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341,
523,
390,
532
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[
236,
540,
277,
549
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[
285,
543,
292,
545
],
[
300,
538,
335,
547
],
[
342,
536,
390,
545
],
[
237,
553,
278,
563
],
[
286,
557,
292,
559
],
[
301,
552,
335,
561
],
[
342,
550,
390,
559
],
[
104,
583,
152,
592
],
[
159,
582,
222,
591
],
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231,
580,
279,
590
],
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286,
582,
314,
587
],
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321,
578,
350,
587
],
[
357,
578,
370,
587
],
[
378,
577,
391,
585
],
[
398,
576,
426,
585
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[
433,
576,
445,
584
],
[
454,
575,
501,
584
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509,
574,
529,
582
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537,
574,
543,
582
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[
105,
597,
139,
606
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[
146,
596,
214,
607
],
[
105,
625,
125,
633
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[
133,
624,
172,
634
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[
182,
623,
216,
632
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[
224,
622,
258,
631
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[
266,
622,
294,
629
],
[
302,
619,
343,
628
],
[
352,
618,
371,
627
]
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[
"BROWN f& WILLIAMSON TOBACCO CORPORATION RESEARCH & DEVELOPMENT THTERNAL Tor. B. A. Reasor ce: A. H. L. Reynolds B. A. Kerr AL 3. Golub H.C. Woerte A. P. L. Chen. A. Goodman DATE: November 2, 1990 SUBJECT: DUPONE RESULTS FOR MENTHOL PERCEPTION BELATR LTS - RIGH/313 DETAILS Attached are Monadic Attribute and analytical results, The following products were evaluated: 313080 ~ 0.65% MENTHOL/CONTROL. 313081 — 0.75% MENTHOL 313082 ~ 0.82% MENTHOL 313083 - 0.91% MENTEOL 313084 ~ 1.00% MENTHOL Monadic Attribute ratings were made by 54 LD-M KS smokers and 9 PRISM paneliste. ‘The Dupont study I.D.s were 900253 and 900254, COMMENTS None. } P. A. Goodman 26171 505501605"
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771
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[
". : 4 . it 42nd tew York, New Yo 3 New 30007 SS fate : Circular No. 2486 May 5, 1971 3 ade : ANNOUNCING KENT MENTHOL KING SIZE CIGARETTES 0 OUR CUSTOMERS IN THE STATES OF: ‘ALABAMA ARKANSAS NORTH DAKOTA KANSAS. OKLAHOMA th MISSISSIPPI MINNESOTA NEBRASKA COLORADO TEXAS LOUISIANA SOUTH DAKOTA WYOMING NEW MEXICO” § FLORIDA: The following Counties: 3 Holmes Washington Bay Santa Rosa Watton Jackson cult ILLINOIS: The following Counties: Madison Moncoe : Except Scott County * WISCONSIN: Douglas County only, KENT got it all together again . . . NOW THERE'S KENT MENTHOL KING SIZE TOO! with the exclusive Micronite Filter .. . and the good rich taste of KENT. We've taken all the good things of KENT MENTHOL ig 1100's, and got them together for sniokers who prefer KING-SIZE. LIST PRICE: $10.25 per M. TERMS: ‘We will allow special discount terms as follows: THE TOTAL 3% DISCOUNT WILL BE AVAILABLE ON 4NVOICES FOR KENT MENTHOL KING SIZE DATED. THROUGH MAY 26, 1971. 1F PAYMENT IS RECEIVED AT OUR REMITTANCE ADDRESS NO LATER THAN THE 30TH DAY AFTER INVOICE DATE. ‘THESE SPECIAL TERIAS WILL APPLY ONLY TO KENT MENTHOL KING SIZE LS TO PURCHASES UP 10 THE AMOUNT OF YOUR ALLOCATION. PACKING: KING SIZE Cup (soft) packages of 20's, cartons of 200, shipping containers SHIPMENTS: First deliveries of KENT MENTHOL KING SIZE Cigarettes will be made May td 13, 1971 to Lorillard customers in the areas outlined above. ALLOWANCE: — An Introductory allowance of per M ($6.00 per case of 12M) will be | BW given on KENT MENTHOL KING SIZE Cigarettes beginning May 13, 1971 oe through May 28, 1971, This allowance will be deducted ftom the face of invoices and applies to purchases of KET MENTHOL KING SIZE only. i Pa gfe - . 7 ve"
] |
[
[
16,
39,
739,
961
]
] | 0
|
|
1,000
| 774
|
form
|
[
"RJRI INI , INC,",
"aJ:",
"Reynolds Tobacco Interational Inc",
"Feb",
"1902",
"TI Rc",
"RUr",
"Form 0d0]",
"Jjrt",
"CHANGT/2-82",
"Den",
"fion",
"AUTHORIZATION FoR",
"January 21 ,",
"1982",
"Area",
"III",
"Brazi]",
"002-82",
"Date",
"BR",
"Operating Area /Unit",
"AC No_",
"New_Brand Introduction (Test Market)",
"Came]",
"Filters",
"MAP-9-1982",
"Subject /Location",
"Unit Ref.",
"Approvab",
"Requested",
"Rpreve\"",
"This",
"request",
"for the introduction of Came",
"Filters into the Curitiba",
"Test Market",
"1982",
"on Apri",
"the",
"introduction of Came",
"Filters",
"the",
"brand group wants",
"to tes",
"dentified,",
"exploiting",
"marke",
"that has",
"recently been",
"Specifically",
"the",
"brand group",
"Camepportunity",
"to test",
"Filters",
"proposes",
"an alternative to Ho]lywood",
"eydvanesgeb9ishc",
"taking",
"of Ho] Iywood",
"product Tife",
"Moreover",
"maturity",
"Filters has",
"Came",
"opoo",
"unique",
"portunity",
"itself",
"ma le cigarette without",
"the",
"Iy negative perceptions of",
"9659893",
"usua",
"and too downscale",
"Currently there",
"no cigarette in the market",
"with such",
"unique",
"oning",
"If after",
"Came] Filters achieves its",
"twenty",
"0 SOM objective",
"our",
"weeks",
"and has shown",
"tnat",
"ievel,",
"sustain this share",
"can",
"the",
"brand",
"wil)",
"be ro] led-out",
"nationa ly",
"on October 25, 1982",
"L-J+I",
"(Attach Summar Discussion ol Roporal)",
"Change",
"Type of",
"Contractua",
"Commitment (Specify",
"0",
"Selling Price",
"Change",
"Type)",
"Chenge",
"Expense",
"Working Capital Change",
"Raw Materials",
"Inventories",
"BEST",
"Wage",
"Fringe",
"Salary.",
"Scales",
"Benefits",
"Receivables",
"{",
"COPY ,",
"Headcount Change",
"Other",
"Other",
"Amount of Change:",
"Policy",
"Change",
"Change from Budget /Plan:",
"LX New Product Introduction",
"Other ,_",
"Is this",
"lated",
"previous proposal?",
"Yes",
"Yes,",
"describe",
"attached",
"Initia",
"Post",
"Evaluation Date Sept_22",
"982",
"Will subsequent commitments",
"required?",
"Yes",
"diccussion",
"Iummtn",
"VHENY",
"AHNU",
"19_82",
"19 85",
"19 86",
"Eximuted Profit/Loss lmpuct:",
"637",
"738)",
"430",
"2,643",
"3,416",
"From",
"Earnings",
"Operations",
"1.427",
"1,845",
"884",
"(399)",
"232",
"Earnings From Operations(Aftax)",
"(738)",
"322",
"430",
"2,643",
"3,416",
"Budoet /Plan EFO Change",
"APPROVALS",
"OPERATING UniT",
"AREA H.a:",
"RJrTi",
"Signature",
"Signature",
"Date",
"Signature",
"Date",
"Date",
"Jo_LL",
"Pig:Pla",
"Ji2sL",
"Brand Mgnt.",
"' Yi44",
"RI",
"EE82",
"eez]",
"xhbx",
"Pir.Lega]",
"Iixa",
"Lsla",
"Oper_",
"Zneb",
"Liky",
"Fin",
"Mktg.",
"Rres idew"
] |
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27,
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] |
[
"RJRI INI , INC,",
"aJ: Reynolds Tobacco Interational Inc Feb TI Rc 1902 Jjrt Form 0d0] RUr CHANGT/2-82 AUTHORIZATION FoR Den fion Date January 21 , 1982 Operating Area /Unit Area III Brazi] AC No_ BR 002-82 Subject /Location New_Brand Introduction (Test Market) Came] Filters Unit Ref. MAP-9-1982",
"Approvab Requested This request Rpreve\" for the introduction of Came Filters into the Curitiba Test Market on Apri 1982 the introduction of Came Filters the brand group wants to tes exploiting marke Camepportunity that has recently been dentified, Specifically the brand group proposes to test Filters an alternative to Ho]lywood taking eydvanesgeb9ishc of Ho] Iywood product Tife maturity Moreover Came Filters has unique opoo portunity itself ma le cigarette without the usua Iy negative perceptions of and too downscale Currently there no cigarette in the market with such unique 9659893 oning If after twenty our weeks Came] Filters achieves its 0 SOM objective and has shown ievel, tnat can sustain this share the brand wil) be ro] led-out nationa ly on October 25, 1982",
"L-J+I",
"(Attach Summar Discussion ol Roporal)",
"Type of Change Selling Price Change Expense Chenge Raw Materials Salary. Wage Scales Fringe Benefits Headcount Change Other Policy Change LX New Product Introduction",
"Contractua Commitment (Specify Type) Working Capital Change Inventories Receivables Other Amount of Change: Change from Budget /Plan: Other ,_",
"0 {",
"BEST COPY ,",
"Is this lated previous proposal? Will subsequent commitments required?",
"Yes Yes",
"Yes, describe attached Iummtn diccussion",
"Initia Post Evaluation Date Sept_22 982 VHENY AHNU 19 86 3,416 1,845 3,416",
"19_82 637 884 322",
"19 85 2,643 1.427 2,643",
"Eximuted Profit/Loss lmpuct: Earnings From Operations Earnings From Operations(Aftax) Budoet /Plan EFO Change",
"738) (399) (738)",
"430",
"232 430",
"APPROVALS OPERATING UniT AREA H.a: Signature Date Signature Date Signature Brand Mgnt. Jo_LL Ji2sL Pig:Pla ' Yi44 Pir.Lega] RI eez] EE82 xhbx Oper_ Iixa Zneb Lsla Fin Liky",
"RJrTi",
"Date",
"Mktg.",
"Rres idew"
] |
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[
27,
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987
]
] | 1
|
|
1,000
| 754
|
presentation
|
[
"12/s(14",
"(BAPensATin",
"KozolouJJk ;",
"DveArEads",
"Compensation",
"Compensation and Low",
"Yield Cigarettes",
"Lynn \"",
"Kodowekl PhD:",
"Does",
"brand-swilching",
"Prolateot4nd Hled",
"smoker",
"oversmoke",
"Progrm",
"Blobahavoral Haaltn",
"lower nicotina cigaretto?",
"Colleot-",
"Haalth end Human Davelopmani",
"Th Pennaylvnui sub Unlvrlty",
"Answor: Yes:",
"Unlverelly Perk PA 16402",
"Ground Rules",
"\"Hydraulics\"",
"Per clgarotto adjustments only",
"The FTC Iost @ 4 por-clgaratto tost",
"approximate what would happen If",
"should be judgad",
"Ruch",
"number ot cigarettes were fixed_",
"Forty low calorle candy ban May",
"~2 mg X 20 cigs",
"mglday",
"togolhar be hlgh calorle and atIII",
"~4mg X 10 cigs",
"mglday",
"Indlvidually bt low calorlo.",
"~0.8 mg X 5 cigs",
"mgday",
"Importance of brand-",
"Compensatory % Chango in",
"Cigarettes per Day",
"switching research_",
"Repeated-measures deelgns",
"Mean",
"+15%",
"control Ior individual dlilerences:",
"(95% Cl=t6)",
"~dnug Motabollem",
"brnd golaetlon",
"blaser",
"(#ussortatlve mating )",
"[No decreased intake]",
"Page",
"89241644"
] |
[
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514,
102,
570,
126
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109,
505,
123
],
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219,
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303,
127
],
[
307,
111,
377,
125
],
[
402,
224,
568,
254
],
[
141,
225,
305,
241
],
[
165,
237,
279,
257
],
[
125,
273,
153,
287
],
[
161,
273,
237,
287
],
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[
545,
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[
"(BAPensATin 12/s(14",
"KozolouJJk ; DveArEads",
"Compensation",
"Compensation and Low Yield Cigarettes",
"Lynn \" Kodowekl PhD: Prolateot4nd Hled Progrm Blobahavoral Haaltn Colleot- Haalth end Human Davelopmani Th Pennaylvnui sub Unlvrlty Unlverelly Perk PA 16402",
"Does brand-swilching smoker oversmoke lower nicotina cigaretto?",
"Answor: Yes:",
"Ground Rules",
"\"Hydraulics\" Per clgarotto adjustments only approximate what would happen If number ot cigarettes were fixed_ ~2 mg X 20 cigs mglday ~4mg X 10 cigs mglday ~0.8 mg X 5 cigs mgday",
"The FTC Iost @ 4 por-clgaratto tost should be judgad Ruch",
"Forty low calorle candy ban May togolhar be hlgh calorle and atIII Indlvidually bt low calorlo.",
"Importance of brand- switching research_ Repeated-measures deelgns control Ior individual dlilerences: ~dnug Motabollem",
"Compensatory % Chango in Cigarettes per Day",
"Mean +15% (95% Cl=t6)",
"blaser brnd golaetlon (#ussortatlve mating )",
"[No decreased intake]",
"Page",
"89241644"
] |
[
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545,
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] | 12
|
|
718
| 1,000
|
scientific publication
|
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[
"Jounal of $13 (1993) 95103 Evie BV, Amsterdam chromato, High-performance liquid chromatographic determination of nicotine and its urinary metabolites via their 1,3- diethyl-2-thiobarbituric acid derivatives Klaus Rustemeier*, Demetrios Demetriou, Georg Schepers and Peter Voncken fr 2, W-S000 Kan 90 (Fi ane 288, 1992; November TR, 1992) ABSTRACT ‘The | igh fr rictne ha been hat ican be wed determine the concentration of nine nd upto 1 bole ine urn of humane ne Wbortoy ail, plate tebe “Th produts of lavage found in ite vere nil ene cosine. aa sal mount Felloving anaes showed the ofthe rietne DETEA dernatne 1 te ie ef DESTA an the wk of nicotine INTRODUCTION low [6] reported that, by using an extraction pro- cedure, the sensitivity of the assay was enhanced, In recent years the metabolism of nicotine has et af, [7], in addition to determining been found to be very complex, Moré than 20 nicotine and cotinine, were able 10 determine urinary nicotine metabolites have been described three identified metabolites vsing modified chro- (1). For their determination in the urine of hu- matographie conditions. Barlow er al. {5} and mans and laboratory animals, an appropriate O'Doherty eral (7] proposed that the mechanism analytical method is required, However, only a of the derivatization reaction is based, analogous few methods that can quantify more than two to the reaction (8), ona sing-opening reac- metabolites simultaneously have been reported, _ tion of the pyridine substructure, starting with an and these generally require the use of electrophilic attack on the pyridine nitrogen, If ly labeled nicotine Barlow er af. de- this is true, only those metabolites that scribed a pre-column derivatization method an intact pyridine ring and bear no substituent at yielding acid (DET- the nitrogen atom can undergo this reaction. This BA) derivatives, which can be separated by high- is the case for the majority of the known nicotine performance liquid chromatography (HPLC), metabolites with few exception, eg. cotinine-N- ‘They were able to determine nicotine and coti- oxide and the previously reported Neglucuro- nine. In addition, they observed five metabolites _nides (9). that they could not identify, Parviainen and Bar- This paper describes the extension of the HPLC assay to detect and quamtty all those me- tabolites in the urine of humans and laboratory g * Corresponding author. animals that form DETBA derivatives, As the 3 g $06.00 ©1993 Elsevier Science Publishers All ighiseeseried 3"
] |
[
[
56,
82,
657,
887
]
] | 6
|
|
754
| 1,000
|
questionnaire
|
[
"ra",
"‘T-127",
"032387/1",
"cigarettes",
"Hello,",
"I'm",
"of",
".",
"We",
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"No",
"2.",
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"(TERMINATE)",
"3.",
"May",
"T",
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"person?",
"(IP",
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"MAKE",
"APPOINTMENT",
"70",
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[
"ra ‘T-127 032387/1 cigarettes Hello, I'm of . We are conducting a brief survey on cigarettes and would like to include your opinions. 1. First, is there anyone Living in your household who is enployed in the sale, manufacture or distribution of tobacco products, or in market research, or advertising? Yes (TERMINATE) No 2. Is there a person living in your home between the ages of 21 and 59 who snokes at least 10 cigarettes per day? ves No. (TERMINATE) 3. May T speak to that person? (IP NOT AVAILABLE, MAKE APPOINTMENT 70 CALL LATER. SAVE SCREENER. GET NAME AND TELEPHONE NUMBER.) 4. Is your regular brand of cigarettes a filter or non-filter 8 cigarette? Filter g Non-filter & 8 5. Is your regular brand of cigarettes menthol or non-menthol? Non-menthol"
] |
[
[
86,
92,
659,
876
]
] | 13
|
|
1,000
| 754
|
budget
|
[
"ST;-",
"AuG",
"9 IScd",
"THE",
"TOBACCO",
"INSTITUTE",
"STATE ACTIVITIES",
"CONTRIBUTION /HONORARIUM",
"REQUEST",
"Contribuci",
"CHECK ONE :",
"Honorariun:",
"771728",
"1.D",
"Soc",
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491,
917,
589,
937
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[
"ST;- AuG 9 IScd",
"THE TOBACCO INSTITUTE STATE ACTIVITIES CONTRIBUTION /HONORARIUM REQUEST",
"Contribuci 1.D 771728",
"CHECK ONE :",
"Honorariun: Soc Sec . #",
"RECIPIENT INFOREMATION",
"Nane Fr4z Robert Adatess 3088 Pico Address Suite 200 Carlsbad CA 92008 Eest/zIP: The Honorabl - Salutation: Assenblyman Frazee",
"Scate: Incurbent (Yin) : Party (DIR/O} : Indivldual/Group",
"RUNNINGFOR (CHECK",
"HORE TAAN ONE I4 EACH COLUHN)",
"(2)",
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"(2)",
"LEGISLATURE : EXECUTIVE :",
"UPPER LOWER CITY COUNTY :",
"COMHITTEE ASS GNFENTS (CHEcR AS TAMY As APPLY )",
"Finance: Judiciary:",
"Healch:",
"Rules : Other (exp l2in)",
"Bus iness",
"CHECKINFORATTON Imnediately",
"Amounc (S):",
"O0O,",
"Needed DY :",
"Payable Address Address City/ST/ZIF:",
"Friends Bob Frezee 1228 Screet Suiee Sacrarenco CA 95814",
"Cost Center: Account",
"Honorarium details: Ocher comments",
"APPROVAL",
"Legislative Counsel: A-K fssocades Regional John Sector V.P. \"mnrroz",
"TCALO414311"
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93,
771,
372,
822
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[
491,
917,
589,
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] | 10
|
|
762
| 1,000
|
form
|
[
"wy",
"RESEARCH",
"&",
"BROWN",
"&",
"WILLIAMSON",
"DEVELOPMENT",
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"|",
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530,
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607
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593,
156,
614
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655
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643,
507,
680
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341,
675,
361,
691
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440,
677,
468,
686
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440,
675,
663,
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704,
120,
713
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226,
705,
240,
716
],
[
371,
705,
386,
716
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4,
955,
78,
964
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2,
971,
68,
980
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971,
115,
980
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126,
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151,
980
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161,
971,
185,
980
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197,
971,
230,
980
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] |
[
"wy RESEARCH & BROWN & WILLIAMSON DEVELOPMENT NONMENTHOL INTERNAL PANEL SENSORY (paired Dtferencey Oud lo 24-78 NAME DATE SAMPLE vs. ‘SAMPLE Impact: fo. (2) Fal BODY: ar we AMOUNT OF 5G) @ Vere HO) ToBacco Tst: 4 : BETTER ry (0) TOBACCO TST: ae | orrraste: fig 4 o | HARD TO. (2) 10 (2) ‘Oe DRAW. ae ea ae ee PREFERENCE (2) () 440007623 PRODUCED FROM B&W WEB SITE"
] |
[
[
2,
75,
663,
980
]
] | 1
|
|
754
| 1,000
|
specification
|
[
"ASIC",
"WEIGHT",
"SPECLFLCATION",
"Loursvrite",
"EFFECTIVE",
"DATE:",
"09/29/1995",
"GENERALS",
"NON-FILTER",
"KS",
"REGULAR",
"SP",
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"PRODUCTION",
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"26.2812",
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":",
"13.00",
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"TOTAL",
"Less",
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"3",
"1",
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"CIGARETTES",
"PREPARED",
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[
"ASIC WEIGHT SPECLFLCATION Loursvrite EFFECTIVE DATE: 09/29/1995 GENERALS NON-FILTER KS REGULAR SP STANDARD PRODUCTION BRAND CODE-06990 (STD) PHYSICAL PARAMETERS ROD LENGTH: 1 PAPER KIDTH + 27.00 CIRCUMFERENCE 24.80 CALCULATED VOLUME cusic HM CALCULATED DENSITY 26.2812 TARGETS PACK v : 13.00 xm TARGET 3.20 om RANGE FROM 2.80 TO CONE MEEK RANGE: FROM 3.10 (EIGHT WEEK FILLER 9962027 ‘CALCULATED WEIGHT: 2.1965 Les. PAPER AND. ADHESIVE werGHT TOTAL Less PLUG ‘GRAMS REASON FOR CHANGE SPECIFICATION UPDATED To REFLECT UPDATED PAPER 2 AND WEIGHT AND/OR TIPPING AND ADHESIVE = WEIGHT, TOTAL LESS PLUG WEIGHT CHANGED. OK TO 3 1 MDX CIGARETTES PREPARED BY Kev. PRINTING DATE PREPARATION DATE 2 9/2/95 APPROVED BY. SUPERCEDES SPECIFICATION DATED: 4/27/95"
] |
[
[
85,
97,
680,
928
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|
|
754
| 1,000
|
email
|
[
"2077981575",
"yp",
"Page",
"1",
"as",
"4",
":",
"Note",
"for",
"Mahon,",
"Jean",
"yp",
"ie",
"4",
"A",
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"John",
"ye",
"w",
"Date:",
"Fri,",
"Jan",
"3,",
"1997",
"6:43",
"AM",
"\\",
"iP",
"Subject:",
"RE:",
"Records",
"os",
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"J",
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"Jean;",
"Purcell,",
"Clare",
"ti",
"\\A",
"aw!",
"a",
"ce:",
"King,",
"Valerie",
"ak",
"¥",
"Based",
"on",
"your",
"brief",
"description,",
"I",
"end",
"to",
"doubt",
"that",
"any",
"of",
"the",
"materials",
"have",
"any",
"value",
"to",
"in",
"the",
"role",
"she",
"now",
"plays",
"and",
"do",
"not",
"see",
"much",
"purpose",
"in",
"moving",
"the",
"records",
"to",
"Jean,",
"You",
"and",
"Clare",
"can",
"discuss",
"and",
"determine",
"if",
"they",
"have",
"vaiue",
"to",
"Jean's",
"position",
"in"
] |
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[
"2077981575 yp Page 1 as 4 : Note for Mahon, Jean yp ie 4 A From Mulderig, John ye w Date: Fri, Jan 3, 1997 6:43 AM \\ iP Subject: RE: Records os Se J To: Mahon, Jean; Purcell, Clare ti \\A aw! a ce: King, Valerie ak ¥ Based on your brief description, I end to doubt that any of the materials have any value to in the role she now plays and do not see much purpose in moving the records to Jean, You and Clare can discuss and determine if they have vaiue to Jean's position in its present form. If the records do not have any present use, they should be evaluated for disposal suspension and if on disposal suspension, permanently retained as part of Clare's inactive files. Bill Lynch can assist in the evaluation, Tf not on disposal suspension, the records should be managed pursuant to applicable records retention schedules and procedures for records not on disposal suspension, John"
] |
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20,
115,
682,
442
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1,000
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handwritten
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119,
600,
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1,000
| 754
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scientific publication
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[
"KoTice",
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"Tracer tor Environmenlal Tobacco Smoke Partlcles",
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"Lereral sudies '16, !4. 651 Euve shown",
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"enlronmcni",
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"pcpulqil",
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"Ahut hal of the RSP",
"[eX tntronmenu does not corns",
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"ent",
"Results Irom",
"~unesol",
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"toEacco Ieaf .",
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"Ice delerminaliln",
"chich,chcich,i_CHICH,OH",
"p4fucuIC pnosc",
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"ch cich;-",
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"smokc",
"and indcl",
"pntironmenis thow",
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"Jnbletacdr",
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"Rnirkn",
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"Ianace Imoikc rnmaknaato",
"VG. 47) al rnerrmmenul Iabato",
"(rmhitrM(iucCO 4Imu40",
"shwke (I0, Im",
"Studlc",
"pfeviqusiy reportcd",
"a4 148, /91 subecs",
"Urden",
"Inlrrductton",
"the concentration",
"ETS particles",
"COntacn",
"conse",
"the inaoor",
"Anvmonmanl",
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"Vutil",
"Envionmental",
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"Impcrtant",
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"Lobacco !moke",
"Fio",
"7-eehanvipytidin",
"Jaleroired Dy",
"LDpl",
"Aenu",
"benzencoufonicacid coatrd annulrdenidat oloxtdhi",
"Eng-phcle",
"nicotine 04}",
"luduelidle eipoure",
"ETS",
"In addition: the gas- (p4ticu-",
"Tellon (liter",
"Daeticule",
"Jcnye",
"quartz",
"couact",
"parelcic",
"Jkaloids",
"iate-phese distribution",
"dujing",
"coated quartz (Ulae",
"nicolinaMr",
"Wilered",
"Leneuonic 4C.0",
"LAp LDY",
"I",
"particles",
"sampling,",
"praviously d&",
"duling",
"Badre et al. (II} found 4n 80% lou",
"Ioat Irom the",
"ddcd",
"lmeling",
"s4mpling (or 50 min",
"sctibed",
"flter",
"elter",
"nicoline",
"Upom",
"Jlandard L/win (Lpm) Similar etfects havt been noted",
"particulet",
"umnienor",
"The drlatinalion ocolinaol",
"umpling",
"when zmplinz",
"ALso obulned durinz",
"nicotine",
"envonmental",
"tobecco",
"JLOY",
"ccmpate",
"ilers (12,",
"urhnquca (or nicotine ((J1 Enyronmental tobacco smoke",
"UDarinanbam",
"Hinorl",
"puricles",
"the chamtenafiaty",
"concontralion and phase",
"nicor",
"Jermjined",
"distributicn",
"tnes",
"J[udie?",
"anerato",
"The con-",
"dependent on the ucpling syatetn Ised:",
"the Pierce",
"Licoralor",
"Yoluntr",
"JEoten",
"tine mey thld",
"tatal",
"caciracion",
"LohaccoaMorcconntvenb Kn",
"coneollad",
"ctha Paet mch whch i m;",
"3ecun",
"Gnc int",
"Samplaa",
"cham b",
"RSP has",
"by the Iale",
"comoniy",
"Mro",
"LEeCer",
"envircn-",
"Vanthaation_",
"tor deler-",
"cotn",
"Tellon",
"paat studies",
"Jorctec",
"3ollnm4ol",
"rnlacteu",
"47-DD",
"menli",
"Lobicco gmoke",
"mnattol",
"00119301/90/0924 3840102 50/0",
"1920 Lmarcn Chenkal Soclat",
"Envton",
"Tocnnd"
] |
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[
"KoTice Ibls Tateriel potacted Ccoytiett hr Miwe 47 US Cocel.",
"{o",
"Tacao",
"Solanesol:",
"Tracer tor Environmenlal Tobacco Smoke Partlcles",
"Hongmao Targ 54lan Alchardt Cynthla Jonatr Hantan Delbart Ealouah Crent Cezacmect Miotan Tcu Univa'5ity T0t0",
"Tuomlnan Mron",
"Edhin",
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"04602",
"Lereral sudies '16, !4. 651 Euve shown thot gven chouzh RAP Wlerad enlronmcni Tneee smozu peMen Ahut hal of the RSP [eX tntronmenu does not corns Trumentodmente [odecloAMoxs RSPthus uvere:ei- Inulei crousufe enetonmtnin drCcn ~unesol [fsesa ullerpc NI}Icicoho toEacco Ieaf . ch cich;- chich,chcich,i_CHICH,OH Rnirkn Jiync Ianace Imoikc rnmaknaato VG. 47) al rnerrmmenul Iabato shwke (I0, Im Studlc pfeviqusiy reportcd Urden a4 148, /91 subecs the concentration COntacn ETS particles conse the inaoor Anvmonmanl Solnero nonvo Vutil Cnme Htoecu weignt (631) and nerce present Only tne pucicuilte phalt Fdutcnmania FeoaCm amoleuci Drdtt potenuid use & Tolnmiol Iraccr {or cnvironmcntal [ovicco Gmoi eva lualed Tha concontrallon' Folenerol controlled Lhumbar Fuoten Incong environmienel {obacco imote daterminto compafed Yeyerd olher componenty ETS:",
"Lunchn Aul . pakh 2ea Jste sMcriny lnd crnu Lin BTRE pcpulqil rnrtonmentl lobacco \"moke na\"c Renerollo Une need Jo: quantmnscteacet en ronmenton (Dbacco sMoke Sulanesol Trisesqui Cercenoicacono S7mun crlerh' ent Foaimenia cdbcco Smua Results Irom Ice delerminaliln p4fucuIC pnosc Squantsc enfionmental (obce smokc hoLz camber and indcl pntironmenis thow Thal alanesrl Jnbletacdr aeen puF( c udlr Mnuat (rmhitrM(iucCO 4Imu40",
"Inlrrductton Envionmental Lobuczo sMokt ETSI Impcrtant cumconcne ndoorar pollulon Data Ihe |itctaturc Indicaic #inoqurl cnurenmeni (quacco Imore lcad: Increlsed Incidence [hditanr' Dncal the inpairment Jnr derelopmen children; and (it dctrlodment olure cAnCEI 21. These heakth cona Cleny 40 frgotune Mane popuaon Anviron. Mencni tonncso So le Ccn m[eo quanjalye accr ETS; accoroinz revicu by [ne Naliona Acndemn Sciences {uitaole acar quaneilyinz envifon: necla [Obacco #DlOk cuncentealions snoud 30 (I) unique eari u4de CacitohtENA Lglbncct Smold easily detecud 10* stnolgN (Jlsimlla cmgion ntcs vaniely todacrer and (41 congian zroporticn compounds ETS have e human henth; Tractna tn ronmentu lducco 4mor P ncuae respirable total) sws- pendce Dericuie maler (RSPA CO. nitrorcn orides: nlcotine A-nilrornintl gtomalic vdtccnrdona irequency smoking Receat Ceteans environmenui {douccoumo by thc Natianal Aczatmy ol Scicnces I 1 17 @ecn US Sureeon Ganten (2) reach the J4me cr Ficlu- Aicn Cceced previolly Eha L May relatec t0 actual expodre entonmtnta tocacco MOEE Dct concenialions nicotine RSF. poinged out Enes reviery bcth cncso ttJcers potentia prcblems Tar We nucdune HaGL enttonteni Lobacco inicke complicateo by te fact chat nicotine [cunc primarily Dinst tntronment 6-51 Furthermore ncolh strongly cic Ann Femotad Tram Indcor enitonmeni Tuter Fle than puticu Wte-nhra ricotint the particulju Partion entiron Aenu Lobacco !moke Fio Tnws, the corcontration Eng-phcle nicotine 04} luduelidle eipoure Daeticule Jcnye ETS In addition: the gas- (p4ticu- iate-phese distribution nicolinaMr Wilered dujing lmeling Badre et al. (II} found 4n 80% lou ddcd nicoline Upom flter elter s4mpling (or 50 min Jlandard L/win (Lpm) Similar etfects havt been noted when zmplinz nicotine envonmental tobecco Hinorl puricles ilers (12, UDarinanbam Jermjined concontralion and phase distributicn nicor tine mey thld dependent on the ucpling syatetn Ised: 3ecun ctha Paet mch whch i m; Gnc int tatal RSP has cotn comoniy Mro LEeCer envircn- menli Lobicco gmoke paat studies Jorctec",
"Methods Sumple Collectlon_ Particulate amplcs (or tnc de Terminaicr Golnnaol simulated environmental {0- bacco smore WCIO Obtained FFOm Jidestream Jmoke gen- Frnico collopaabl JO-m' Tllon chamber (5, 61- Itet xptnmenu citker onc-half or four cizarettes (IRL 4nd [RF rescarch cigarelled , Univeraiey Ren(lcly #oridtco the Teflon chamber using standard Gyclc Ihe mAmJLrcam cortion tht Jmoke %As vented to Junic the chall Samplca of tha goneratod Darlic[69 306o ntoun A0DD Tellon Iina and collectod on quartz IIltn (2800 4iST; Pallller Producu Comp Lhntril Oyee Pdod Ater combuation AGeln Belort the nleerMr Anahiro Elibn ficitto 0M (or 12 thorourhly nnurd with waut , id neclee Tiumpla lom rate ## 3o ,Lpm uunduo Uitch Dinuc DY We Ilan DEA Mon' confroler addition colleceion DAceenor the deter- mination Jolanasol, the CQ and particulal fnliatlong Lne chanber during each Ct rDcNmacDa were determintd wnth CO detector 4nd DeonaAnga pIcMiousiy deacribed The concanltalions particulate-put nicotina and ofau-phat nicotine 4no 7-eehanvipytidin Jaleroired Dy LDpl benzencoufonicacid coatrd annulrdenidat oloxtdhi quartz Tellon (liter couact parelcic Leneuonic 4C.0 coated quartz (Ulae LAp LDY Jkaloids Ioat Irom the particles duling sampling, praviously d& sctibed particulet umnienor The drlatinalion ocolinaol ALso obulned durinz JLOY ccmpate umpling urhnquca (or nicotine ((J1 Enyronmental tobacco smoke tnes J[udie? anerato the chamtenafiaty the Pierce Licoralor Yoluntr JEoten The con- caciracion LohaccoaMorcconntvenb Kn coneollad by the Iale cham b Vanthaation_ Samplaa tor deler- mnattol 3ollnm4ol rnlacteu 47-DD Tellon",
"I 00119301/90/0924 3840102 50/0 1920 Lmarcn Chenkal Soclat",
"Envton",
"Tocnnd"
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|
|
1,000
| 786
|
letter
|
[
"Golden Lights",
"07mlrhts Clun; 'rshm)",
"\"1*76-inc",
"i9a0",
"VIvt ;GMI Counliy ( i",
"JnrIh Avenie",
"Ti5",
"Ficchollee. Nev: York 10804",
"0d",
"636-G'Ju0",
"1980",
"May 6",
"Mi:",
"Grian Donnclly",
"Publisher",
"President",
"anld",
"GannLL",
"Westchester",
"Newspapers",
"Gancet",
"Drive",
"\"sh ,rr",
"Whitc Plains ,",
"10605",
"Uistir",
"Dea",
"Briain:",
"U",
"6a'",
"likc",
"Wvould",
"invilc you",
"aid Gannetl",
"Westchesler News",
"1980 ,125,000",
"Lo participace",
"Papers",
"Elie",
"Goldcn",
"Lights",
"May",
"Cha1p",
"26",
"onship",
"L.P.G.4",
"be hela",
"June",
"Wykagy [",
"Ck'",
"Cea",
"Counlry",
"Club",
"New",
"Rochcllc",
"Ncw",
"York _",
"45",
"Kuow",
"che",
"charitahle",
"procccds",
"from (h1is",
"Yol",
"Diil\"",
"year",
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"Aale",
"Lournalment will",
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"Lchesler",
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"Acicy",
"Thc",
"ibucion",
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"YOur special",
"sponsorship is",
"S4",
"cont",
"0o0",
"and",
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"includes",
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"'officiai",
"~inn",
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"Further",
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"progFam _",
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"0 [",
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"look",
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"Bcst rogards",
"&ls _",
"1",
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[
"Golden Lights",
"07mlrhts Clun; 'rshm) \"1*76-inc i9a0 VIvt ;GMI Counliy ( i Ti5 JnrIh Avenie Ficchollee. Nev: York 10804 0d 636-G'Ju0",
"May 6 1980",
"Mi: Grian Donnclly President anld Publisher GannLL Westchester Newspapers Gancet Drive Whitc Plains , 10605",
"\"sh ,rr",
"Uistir",
"Dea Briain:",
"U 6a'",
"Wvould likc invilc you aid Gannetl Westchesler News Papers Lo participace Elie 1980 ,125,000 Goldcn Lights Cha1p onship L.P.G.4 be hela May 26 June Wykagy [ Counlry Club New Rochcllc Ncw York _",
"Ck' Cea",
"45 Yol Diil\" Kuow Lournalment will",
"che charitahle procccds from (h1is year che boys Clubs of Ve Lchesler",
"0'n Aale",
"eiis Acicy",
"Thc cont ibucion Cor YOur special sponsorship is S4 0o0 and includes space identificalion the practice pitching grecn Ewo Pr0 -Am packagcs Ewo preferred parking passes fQu1 Goldcn Clulhousc [adses recofnilion che 'officiai courn;tmenl progFam _ Further we will accommodate any season cickel requcsts YOU may have up tocal 0 f Lwenty (20) _",
"C7t;",
"~inn",
"4oytis",
"Tanta",
"Frey\"sr",
"We incercly appreciate GanneLt Weslchester Newspapers support 0 [ Eln' Golden Lights Chvamp onshi And look [orward your parlicipating this year cournamen",
"Bcst rogards &ls _ CurLis Judgc 1"
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754
| 1,000
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"a egg) °° THE TOBACCO INSTITUTE PAS, es AND DOLLARS | te 19 WA | w | ‘THE 21371 wl 1875 | STREET, NORTHWEST. 5-22-85 De | eat | | | | | i Lo ces sos fe ta aye Aw TCAL0467025"
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[
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|
|
1,000
| 754
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handwritten
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[
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[
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|
|
1,000
| 777
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form
|
[
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|
|
754
| 1,000
|
presentation
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[
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] |
[
[
66,
152,
691,
929
]
] | 12
|
|
762
| 1,000
|
letter
|
[
"|",
"EE",
"|",
"|",
"MEDICAL.",
"COLLEGE",
"OF",
"VIRGINIA",
"§",
"Rim",
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"30,",
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"Robert",
"8,",
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"Research",
"and",
"Development",
"Director",
"ans",
"The",
"American",
"Tobaceo",
"Company",
"ae",
"P.O.",
"Box",
"B99",
"Hopewell,",
"Va.",
"23225",
"Dear",
"Bob:",
"Since",
"the",
"anniversary",
"date",
"of",
"The",
"American",
"Tobacco",
"Company",
"Annual",
"Grant",
"to",
"the",
"Nedical",
"Collece",
"of",
"Virginia",
"for",
"research",
"on",
"tobacco",
"is",
"approaching,",
"|",
"we",
"wish",
"to",
"request",
"support",
"tor",
"the",
"academic",
"year",
"July",
"1,",
"1978",
"-",
"June",
"30,",
"1979",
"in",
"tue",
"amount",
"of",
"$25,000,",
"The’",
"budgetary",
"brealiown",
"is",
"submitted"
] |
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[
"| EE | | MEDICAL. COLLEGE OF VIRGINIA § Rim act 2 | VIRGINIA COMMONWEALTH UNIVERSITY % £ MCV Siation + Virginia 25298 ation | dune 30, 1978 Mr, Robert 8, Sprinkle Research and Development Director ans The American Tobaceo Company ae P.O. Box B99 Hopewell, Va. 23225 Dear Bob: Since the anniversary date of The American Tobacco Company Annual Grant to the Nedical Collece of Virginia for research on tobacco is approaching, | we wish to request support tor the academic year July 1, 1978 - June 30, 1979 in tue amount of $25,000, The’ budgetary brealiown is submitted for Dr. salary $3,000 salary 73960 Secretary salary 93800 Graduate student fellowship 34600 aad supplies 23700 | 835,000 ; We sincerely trust thet this reouest will be considered favorably, An annval report of Guring the current year will be forwarded under separate cover, | Sincerely, Herbert MeKennis, Jr. Professor of Head, Division of Pharmacology"
] |
[
[
23,
0,
669,
707
]
] | 0
|
|
762
| 1,000
|
memo
|
[
"Cc",
"MEMORANDUM",
"TO:",
"IL.",
"FREEDMAN”",
"8.",
"M.",
"FINLEY",
"ce:",
"W.",
"Ly",
"Schermerhorn",
"Ackon-AML.",
"R,",
"A.",
"Veatch",
"R,",
"L.",
"Gustafson-PKG",
"FROM:",
"A,",
"Litwin",
"4",
"ty,",
"ey",
"DATE:",
"March",
"23,",
"1978",
"Ap,",
"ey,",
"“6,",
"SUBJECT:",
"RALEIGH",
"Attached",
"you",
"will",
"find",
"a",
"preliminary",
"writeup",
"on",
"the",
"subject",
"promotion,",
"This",
"will",
"serve",
"to",
"familiarize",
"you",
"with",
"the",
"nature",
"of",
"the",
"program",
"only,",
"as",
"certain",
"elements",
"of",
"it",
"have",
"changed",
"since",
"the",
"write-up",
"was",
"prepared,",
"‘The",
"current",
"objective",
"is",
"to",
"test",
"inarket",
"the",
"promotion",
"in",
"late",
"1978,",
"Ail",
"RALEIGH",
"styles",
"would",
"be",
"featured,",
"not",
"just",
"RALEIGII",
"Lights,",
"PKG",
"is",
"working",
"up",
"a",
"recommendation",
"of",
"test"
] |
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[
"Cc MEMORANDUM TO: IL. FREEDMAN” 8. M. FINLEY ce: W. Ly Schermerhorn Ackon-AML. R, A. Veatch R, L. Gustafson-PKG FROM: A, Litwin 4 ty, ey DATE: March 23, 1978 Ap, ey, “6, SUBJECT: RALEIGH Attached you will find a preliminary writeup on the subject promotion, This will serve to familiarize you with the nature of the program only, as certain elements of it have changed since the write-up was prepared, ‘The current objective is to test inarket the promotion in late 1978, Ail RALEIGH styles would be featured, not just RALEIGII Lights, PKG is working up a recommendation of test cities, Two will probably be used, with corresponding, control markets for each, Neat Steps_ Once this recommendation is received, discussions will resume with Action Marketing and Gillette. Many parameters of the promotion still need to be worked out, You will be apprised of these meetings as they are being scheduled, If you have any comments or questions regarding this promotion, please let me know. 7 J} DAL. 681719126 681719126 PRODUCED FROM B&W WEB SITE"
] |
[
[
2,
14,
649,
980
]
] | 15
|
|
754
| 1,000
|
letter
|
[
"TEMPLE",
"UNIVERSITY",
"School",
"of",
"Medicine",
"Medical",
"Research",
"Balding",
"University",
"Fats",
"Institute",
"for",
"Cancer",
"Broad",
"Street",
"and",
"Molecular",
"Biology",
"10140",
"2084800",
"Fax:",
"(215)",
"707-4318",
"May",
"30,",
"1996",
"Dr.",
"George",
"A.",
"Hasim",
"The",
"Council",
"for",
"Tobacco",
"Research-USA,",
"Inc.",
"900",
"Third",
"Avenue",
"New",
"York,",
"NY",
"10022",
"Dear",
"Dr.",
"Hasim",
"submitting",
"a",
"grant",
"entitled,",
"\"Novel",
"Transcripts",
"Involved",
"In",
"Breast",
"Tumorigenesis\".",
"This",
"grant",
"was",
"previously",
"assigned",
"a",
"#4520.",
"The",
"new",
"proposal",
"represents",
"a",
"revised",
"version",
"of",
"the",
"previous",
"grant.",
"The",
"two",
"reviewers",
"had",
"the",
"following",
"comments",
"on",
"our",
"previous!",
"grant",
"(#4520).",
"The",
"first",
"reviewer",
"was",
"extremely",
"enthusiastic",
"abolit",
"our",
"project.",
"He",
"considered",
"the",
"proposed",
"methodology"
] |
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"TEMPLE UNIVERSITY School of Medicine Medical Research Balding University Fats Institute for Cancer Broad Street and Molecular Biology 10140 2084800 Fax: (215) 707-4318 May 30, 1996 Dr. George A. Hasim The Council for Tobacco Research-USA, Inc. 900 Third Avenue New York, NY 10022 Dear Dr. Hasim submitting a grant entitled, \"Novel Transcripts Involved In Breast Tumorigenesis\". This grant was previously assigned a #4520. The new proposal represents a revised version of the previous grant. The two reviewers had the following comments on our previous! grant (#4520). The first reviewer was extremely enthusiastic abolit our project. He considered the proposed methodology novel, predicted that it would be successful, and recommended the project for funding. The second reviewer, on the other hand, expressed / concerns about the P.l.'s expertise in positional cloning approaches. Per the first reviewer's comment, indeed we have successfully used positional cloning approaches and cloned BRCA2 gene as proposed in our previous application. To address the second reviewer's concern about the P1l.'s expertise in positional cloning approaches we have enclosed our latest publication describing cloning and identification of BRCA2 gene. Since the submission of our previous grant application we have cloned the gene, and hence the revised proposal has entirely different emphasis, i.e. to characterize the tumor suppressor activity of BRCA2 gene. We hope that the reviewers will favorably consider this revised proposal and give the P.l. an opportunity to continue this exciting area of research Sincerely yours, / Raj Kandpal, Ph.D. Assistant Professor"
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"| | ne Eran Now ain! | duced by { on | | CALCTUM INTERACTION: LACK OF | REL ATION BETWEEN ELECTROENCEPHALOGRAPHIC RESPONSE. AND | | ELUID ACETALDEHYDE i: | 0. INDROS aA LARSEN | Reser Labortori of the State (Ako), 380, Hekink 10, end | | Th of University of Mash 26, 8 i 2 | H | SAO | OR 1 sone | | of ale in stein ey human vers | eacbimide-etbano interaction. CSF was sampled va lumbar puncture and blood fom a | i Jl se. CSF and Wnoe concentrations ares fom an ro 210138 0 | son cro | The indicate hat acetaldehyde the human Baie. (EEG) recorded Guin showed ceduton | M. yal with 4 concomitant cent in dee The changes were slr 1 id | observed during ‘normal’ ethanol i | y . ‘The toxicity and chemical reactivity of is well known. Harmful effects ner. Phar | may result if the compound reaches human brain tissue in sufficient concentrations. ‘This may occur when alcoholics begin to drink shortly after having taken aversive 149197 such as calcium carbimide, inhibiting aldehyde metabolism, ' | Penetration of significant amounts of acetaldehyde into human CSF has not been a “* | Only negligible concentrations of acetaldehyde were found in the CSF of : | experimental animals and man during ‘normal’ ethanol intoxication, suggesting cither that substantial amounts of free acetaldehyde do not exist in the blood of | cranial arteries or that the capillary walls and brain tissues have a large capacity to i | acetaldehyde {1}. However, easily penetrated the blood- barr of gosts daring nteacartd infusions 2. Ke was therefore, | Ander, : ie 1 abbreviations: CSF, Mid; EEG, © El NOTICE THIS MATERIAL MAY ot © © Pes || x {TITLE 17, 0008 = 8 3"
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[
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777
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[
"ole ang TS ae ape TEXTILE RESEARCH INSTITUTE at - ae March 8, 1963 pe Helmut Wakeham Wiee President and Director Research and Development Philip Morris Incorporated f y Research Center A em Box 3 D . of Richmond 6, Virginia / pe Subject: Letter Report for the Period February 1 to March 1, 1963 on \"Thermoanalytical Studies of Tobaccos.\" During this period the DTA characterization of both the Ry GHD and NC-CVET tobacco samples, involving duplicate runs for gample in air and triplicate runs in nitrogen atmosphere at was completed on the Stone Preliminary work on TGA operation and techniques was also carried out. ees Since previous work has shown the necessity of large without diluent to get curve detail for runs in get nitrogen the same sample size was used for the GHD samples in air. “The exothermic reactions observed were so large that it Bud was necessary to greatly reduce the signal amplification in order to keep the curve on the chart. Thus, instead of running 20 to 40 microvolts full scale it was necessary to run at ay 2000 microvolts full scale. The ajr curves of the GHD samples showed endothermic peaks around 72° and 160°C by three wel] defined exothermic peaks at about 280° to 285°C, 405°C, and 430° to 440°C. The DTA peak data for the GHD series from runs in both air and nitrogen are summarized in Table 1. In general the reproducibility of peak temperatures is of the order of * 2°C which is about equivalent to the accuracy with which chart temperatures can be read, as the system is Presently set-up, so that in all but one case, exothermic peak 3 (exo-3 in Table 1) for the air curves, the differences in & Peak temperature may not be statistically significant. The reproducibility in peak height was uniformly good in the case (py of the runs in nitrogen and for the runs in air except for = exo peaks 2 and 3. 3 a"
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802
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[
[
173,
81,
705,
902
]
] | 12
|
|
772
| 1,000
|
scientific publication
|
[
"Viewpoints—continued",
"“Where",
"there's",
"smoke.",
".",
"-",
"smokers",
"die",
"of",
"lung",
"eancer",
"each",
"year",
"restrictions",
"that",
"ignore",
"practi-",
"\\",
"The",
"Tobacco",
"institute",
"replies",
"frombreathing",
"others’",
"smoke.”",
"This",
"realities",
"of",
"the",
"workplace.",
"refers",
"to",
"one",
"highly",
"questionable",
"paper",
"and",
"local",
"chambers",
"and",
"busi-",
"As",
"members",
"of",
"state",
"in",
"late",
"1984",
"by",
"two",
"ness",
"associations",
"should",
"continue",
"and",
"local",
"chambers",
"employees,",
"James",
"Repace",
"and",
"to",
"oppose",
"intrusive",
"workplace",
"smoking",
"2",
"of",
"commerce",
"across",
"Alfred",
"Lowrey.",
"The",
"Repace-Lowrey",
"They",
"should",
"provide",
"their",
"o",
"the",
"country,",
"we",
"are",
"Very",
"work",
"was",
"not",
"commissioned",
"by,",
"nor",
"has",
"members",
"with",
"factual",
"information",
"that",
"disappointed",
"with",
"the",
"it"
] |
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[
"Viewpoints—continued “Where there's smoke. . - smokers die of lung eancer each year restrictions that ignore practi- \\ The Tobacco institute replies frombreathing others’ smoke.” This realities of the workplace. refers to one highly questionable paper and local chambers and busi- As members of state in late 1984 by two ness associations should continue and local chambers employees, James Repace and to oppose intrusive workplace smoking 2 of commerce across Alfred Lowrey. The Repace-Lowrey They should provide their o the country, we are Very work was not commissioned by, nor has members with factual information that disappointed with the it been endorsed by any government. all aspects of the issue. article entitled “Clearing agency: The authors wrote independ- Individual decisions concerning work: the air: Chambers cope ently with funding by local anti place smoking policies are best left with smoking in the smoking organizations. The authors employers and their employees. They workplace,\" in your ignored epidemiologic studies that __are in the best position to determine Sue. do not support their hypothesis or rein- policies that meet their specific needs. The article does not the results of still others represent an objective\" article also ignores concli- William Kloepfer, Jr., senior viee View of the various sions from three scientific workshops _president-publie relations, The Tobacco aspects of the work- jn 1983 and 1984 that no conclusion _Institute, 1875 1 Street, Wash- place smoking as been reached about potential health ington, DC 20006. 202/457-4800, Ingcod, number effects of cigarette smoke in the air. 800/424-9876. of chamber execu: ‘The most recent conference, con tives have contacted ducted in with the World usto express Health Organization and the ggnors Note tier concern over the tional Green Cross in Vienna, Austria, | may indeed wish to oppose state ‘The artic aie concluded, “Should lawmakers wish and local ordinances iting he pre article in ‘legislative measures with regard | youdo, and need help waging eu “over half ofthe companies in the coun- £0 take measures with regard | ad the iy to passive smoking, they will, for the a fight contact The try have some sort of formal policy ye Stret, NW, Washington, BC ny P present, not be able to base their efforts | 20006, limiting or forbidding smoking in the Gn a demonstrated health hazard from 2 Some chambers have gone the other workplace.” This statement is not passive smoking” direction beyond ay smoking consistent with the most recent com- \"Bindings\" cited in your article have arranged separ or prehensive tis issue bY alleged | on how fo establish non the Human Resources Policy Sf smokers are, for the most part, ‘moking policies in thei own workplaces, tion of Los Angeles, California. This the work of William L. Weis, Seattle | uted overa hundred I study of 1100 ofthe nation’s largest and University accounting professor who {our interested in hosting fastest growing companies concluded ve Such a Seminar, contact Robert that mest (688 percent) do not have | of tte hiring smokers. Close serutiny of Weis’ | workplace smoking policies but material reveals that his analysis is of Business, Seattle University, Seattle, rather encourage and his conclusions are without | WA 98122 common sense and courtesy to solve Weis himself has acknowledged problems among themselves. eee Although some companies have For example, the claim that established policies (319 most smokers ineur higher medical costs is ae were initiated for traditional safety based on studies that smokers have raiser tor You omens we seco reasons unrelated to any current con: 4 higher accident rate than nonsmokers, troversies, i.e. prohibit smoking while working with hazardous substances, often among blue-collar workers, they @ sensitive machinery and equipment, ot to be engaged in $ food. Few companies (only 2.5 per physical activity and, therefore, are likely 3 cent) prohibit employees from smoking {5 be exposed to physical harm through while on company premises 2 ‘The article presents controversial ‘Ove Wer past years, The Tobacco and inconclusive and eco- Institute has worked closely with a num- nomic research as “findings that most eal af authorities seem to agree upon” withy Commerce and business and industry out referencing the “‘authorities,\" or Scociations who oppose workplace taking into account the experts who legislation because itis have reached disparate conclusions. preempts both employer and One of these reported “findings” is and establiches that “five hundred to 5,000 non- “ 1986 Chanter Execute, ACCE, MSE Duke Src,"
] |
[
[
12,
54,
752,
980
]
] | 6
|
|
1,000
| 757
|
advertisement
|
[
"W47i",
"LC",
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"Frox!iu4 9AS",
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"plssotFolKUEo",
"unkl",
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"Nfri",
"Bulecn Sa4Rz4hVc Het",
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[
"W47i",
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"Icuy plssotFolKUEo",
"unkl",
"Nfri QVBAlsmasNiNG Detcssrett$ Bulecn Sa4Rz4hVc Het",
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[
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[
384,
685,
511,
707
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[
655,
977,
747,
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|
|
1,000
| 776
|
advertisement
|
[
"V",
"1ge",
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"6",
"SATIN Christmas advertising sprcad Inatwill be seen Ihroughoutthe soason",
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"Tha new \"'TRUE, You Found Ir\"' Searchstakes currently being lounched",
"and Sunday supplerents",
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"cerain",
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] |
[
[
710,
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[
500,
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443,
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[
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121,
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[
102,
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205,
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111,
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109,
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[
145,
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]
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[
"V 6",
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"This #peckl SATIN Christmas advertising sprcad Inatwill be seen Ihroughoutthe soason mcgazines cnd Sunday supplements .",
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"L 10t] Tha new \"'TRUE, You Found Ir\"' Searchstakes currently being lounched Moqozines and Sunday supplerents cerain gencratc Iot of atentian among our target smokersl"
] |
[
[
710,
144,
762,
255
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[
436,
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[
93,
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125,
515,
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[
91,
545,
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[
97,
717,
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] | 4
|
|
771
| 1,000
|
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|
754
| 1,000
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scientific publication
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[
"tin Chimica dea, 208 1991 81-94 BV Al igs exred 50 ca ostes Urine thiocyanate:creatinine ratio as a reliable indicator of cigarette smoking Jacques Pré! and Roger Vassy? de Bobigny and de denver ars Nord eb (Frome) 29 1991: evsion resved 26 Seplembe 199: accepted 27 September 1981) ey nnd: to; Urine: Introduction Since cigarette smoking is a risk factor in lung cancer, emphysema, respiratory coronary heart disease and peptic ulcer, the tracking down of active smok~ ing in adults and young people 1 desirable in preventive medicine. A quantitative fo exposure to tobacco smoke would also be useful as an index of success in programmes leading to stopping smoking. ‘A number of chemical markers of tobacco smoking have been described. These include measures based on nicotine (I), cotinine carbon monoxide in expelled air [, 6}, carboxyhaemoglobin (4, 6-9] and thiocyanate (3, 5, 7-16), These measures differ widely in availability, cost and case of administration. Measurements of nico- tine and cotinine have the advantage of being specific to tobacco but require, cially Tor nicotine, expensive laboratory instrumentation (17, 18). While thiocyanate levels, carbon monoxide in expelled ait and carboxyhaemoglobin are easier to deter- mine they may become abnormal through exposure (0 traffic emissions for haemoglobin and diet for thiocyanate. Moreover, carbon monoxide in expelled air and carboxyhaemoglobin in whote blood have the disadvantage of Being very sensi- tive to the mode of smoking (e.g. of puffs taken from each cigarette, length of the butt, inhaling habits) ~ Thioeyanate is an important metabolic product of hydrogen cyanide which is generated by tobacco pyrolysis {19}, the hydrogen cyanide being converted by a thiosulfate transferase named rhodanase (E.C. 2.8.1.1), mainly in hepatic mitochon: ie. de Biochimie Cine, UFR de Medecine de Fait Mascel Cachin, F-99012 Bobpny. France"
] |
[
[
45,
124,
609,
743
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] | 6
|
|
754
| 1,000
|
resume
|
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[
"” ' Stephen B. Baylin, M.D, —— a SKETCH the lntrmation for the key ana sted on page 2. Begln with the Principat ths pape for each person @ NAME POSITION TITLE (Mo.. Day. ¥r) Baylin, Stephen B., Professor of Oncology 10/22/42 _ FOUDATION wi owe dl education suchas nursing. and dude INSMTUTION AND LOCATION oeonee | Duke University, Durham, North Carolina BA. 1964 Psychology Duke University, burham, North Carolina M.D. 1968 Medicine ANO PROFESSIONAL EXPERIENGE Concluding present poston isn chronelogical order, previous employment, experienc, Incl present on any Federal Gvernmentpuble committee List in chronological order, the tiles ans con to al publcalions ine past tee years and Vo earer putications pertinent to this apphestion. OO NO EXCEED TWO PAGES 1968-69 Intern and Assistant Resident, Internal Medicine, Duke University Medical School, Durham, North Carolina 1969-71 Investigator, U.S, Public Health Service, National Heart & Lung Institute, Bethesda, Maryland 1971-72 Assistant’ Resident, Internat Medicine, Johns Hopkins Hospital, Baltimore, Maryland 1972-74 Fellow, Endocrinology and Physiology, Johns Hopkins University School of Medicine 1974-79 Assistant Professor of Oncology and Medicine, Johns Hopkins University Schoo! of Medicine 1974 Physician, Johns Hopkins Hospital, Baltimore, Maryland 1979-87 Associate Frofessor of Oncology and Medicine, The Johns Hopkins University School e of Medicine, Professor of Oncology, The Johns Hopkins University School of Medicine HONORS: Alpha Omega Alpha, Endocrine Society, Recipient of Career Research Development ‘Award from NIH (1975-80), Associate Editor--Cancer Research, American Society of Clinical Investigation (References listed are pertinent to the current Grant Proposal and represent 26 references from a total listing of 138). Griffin, CA, and Baylin, SB. Expression of the C-Myb Oncogene in Human Small Cell Lung Carcinoma. Cancer Res. 45:272-5, 1985. de Bustros, A, Baylin, SB, Berger, CL, Roos, BA, Leong, SS, and Nelkin, BD. Phorbol Esters Increase Calcitonin Gene ‘Transcription and Decrease C-mye mRNA Levels in Cultured Human Medullary Thyroid Carcinoma. J. Biol. Chem. 260:98-104, 1985. Robinson-White, A, Baylin, SB, Olivecrona, T, and Beaven, MA. Binding of Diamine Oxidase Activity to Rat and Guinea Pig Microvascular Endothelial Cells: Comparisons with Lipoprotein Lipase Binding. J. Clin, Invest, 76:93-100, 1985. Gupta, PK, Myers, JD, Baylin, SB, Mulshine, JL, Cuttitta, F, and Gazdar, AF, Improved Antigen Detection in Ethanol-fixed Cytologic Specimens, A’ Modified Avidin-Biotin-Peroxidase Complex (ABC) Method, Diagn. Cytopath. 1:133-6, 1985. Hoppener, JWM, Steenbergh, PH, Zandberg, J, Geurts van Kessel, AHM, Baylin, SB, Nelkin, BD, Jansz, HS, and Lips, CIM. The Second Human Caleitonin/CGRP Gene is Located on Chromosome 11 Hum. Genet. 20:259-263, 1985. Wells, SA, Jr., Dilley, WG, Farndon, JA, Leight, GS, and Baylin, SB. Early Diagnosis and “Treatment of Medullary Thyroid Carcinoma. Arch, Intern, Med. 145:1248-1252, 1985. Wand, GS, Ney, RL, Baylin, Eipper, B, and Mains, RE. Characterization of a Peptide Alpha-Amidation Activity in Human Plasma and Tissues. Metabolism 34:1044-1052, 1985. ~~ e Casero, RA, Jr., Baylin, SB, Nelkin, BD, and Luk, GD, Human Lung Tumor Sensitivity to Difluoromethylornithine as Related to Ornithine Decarboxylase Messenger RNA Levels. Biochem. Biophys. Res. Commun, 134:572-$79, 1986 PS 396 (Rew 865) Page consecutively ain Bott te Dosa ue suchas 8,5 50293617."
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[
"'S 3 Ji-UI Vut Io",
"Cvelt 3rrr AAr",
"THE SICK PERSON EFFECT T, D. STELNNG, WeNNEAY' and Wavcu' ScEaol BC 4.9lCov3atg \"58; Fedar Appued Saera Ind ' Ttodor SOOT Fnet Sutbot Laant} Auoc4L Jurcuby . Vancouy 0 Clud 101307 W. Ii Ar5' VU 02",
"(Lrtrn TTutu",
"Iuy [519)",
"Aes-Vozy olten Titert by wbich uubjau A7 shrted for WOqlled LOTDC Mannet Ibb Wbar hedt. T Helloy Wartarolea ! Huis; Heltby Prron Elct Mortet (KPE) % well baorm Liltk hu67 Enet (HWE) cx In wbxb Ictoa uoqud Mu 'bout &x codyerx (SPE} Tbe SPE my introdua drtls kau ntuk E Skt Penop Etct E<ontro Bu (ot sme cobort mott clinal Sudic #bca nby ur Jtandardized follor-UP: Lnd Im dqmoastte SEDI Hitena of tbe SPE 40 [uppropntle rlertol We ludic: numba of dilcht ditas Study Computz [ inadtrar medial uaIeat Mt thut IGon! indiidutk %bo ten %hated # chibdrtn lor Lmodb LLGI Morbidity jblinp: Ruiot Study (SmRy) [or vnow 15ute cooputdi [ Sundurdind Elve nponed pc Ind shroai ditaue for inlinduab} ~bo coronk syinptoms. Tbe wbere Wbe nper popuhlion SPE #ckaurty \"oarat (Or W insuncs uItD snow Probkms for *t b citnat T*t HPE *d SPE mly nalidity cobcluyons Preiadt MW [pX7 nuk kvrb: Sick Penon Bczt Healby Prron Etect Heluy Wortet Eet Biu Rutk",
"NTODLCTION",
"Indivdul who Juticicatly healthy Very often cniteriz by which Jubjecu Arr selected work 8ryc OI voluatear hive _n for cpidemiologcal studia 'malleranfc 185 uoqled Dorbidity and morualiry which some minner with tci beuluh Thi uriitjon tuat of @ Ienerel popub Jdon. [n consequenc, betwecn slertion criteru tad bealtb Jutu #endurdizin! Dortidiry or morulity DIc\"nn; very noticeable in tdics ol orupttionul hur tbe rcnl popubtjon % refercnt Izults ards. Individuab colendt nbor for 1kso ur Sundurdizad Mornlity Ruatot (SMR) or Sun: In Feasontbly good beulth: Anothat poup tt dudited Morbidity Ratios (SmR) Mtarc Iex; May 6eexDatad to br in [Esontbly tood health Ize Thi dateus in experled SMR Jnd an volunterra Some of tkxe Amercan Cabcrt SoR introdie ! rious dincuty in eulusung Society\" : pumcrous Jtudics ely 00 millions of UrzWu o{ *ma ridcmiologel studics Thl; men and womcd voluotern biw Aqiv Purticipt- conloundini fector Wually cllad tkx tion in such 'ndics ctils Ihut indivdutls % Heulthy Worte BLct (HWE) in occupluonal voluntccring letd w xtve lit for which tlth sndizs bul Muy bat L dekcnbed % U rusonable helt sunu Healthy prereqwuic: Prntod EAI or HPE (1-8}: Studicz of veterans ure YOTy much like Jtudics of unik t HPE bus baro & subjrt ol muny oxupational Foupt; Thry study_populations studia Id dixuriont Letk bu bern 4id thit were Fexonably tood health before they abou5 Lhe CoqvetK Cs, numcly; tbe tituuon were inductcd into Lle 4med fOra which tbe selaction criteriu for study Foup 4n 4Sqlted with dayersd betlth Jutus Suh In Aullor (Or Cntpoddna (Tt: (604129[-Asitjr[Xu) usquuon Muy exist in many clinieul follow up studie Eumple slatons study",
"MASTER-SPp 001694"
] |
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873
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[
451,
943,
730,
981
]
] | 6
|
|
1,000
| 765
|
advertisement
|
[
"17;",
"Hyouzlorvtarhad",
"Tareytons fltes youd",
"besmokingabetter",
"cigarette:",
"2",
"ourprcseneniter",
"0",
"1747",
"only daing halfthejob",
"De4m",
"Tareyton",
"1",
"Hhere snosubsutu",
"din6rr",
"lights",
"foz lieyto gIghcs",
"DeS",
"me",
"100-9m12",
"LowI",
"Hareyton",
"lighs",
"I",
"Wertv\"cg: The Jurgeon General Ha: Determined",
"our Heaith",
"mhat Cigarette Smoting |: Dangerotz (0",
"pa Garule 6y FTC method",
"M; \". 0.6 mG, akjini",
"Enon Ion; Enis"
] |
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[
"17; Hyouzlorvtarhad Tareytons fltes youd besmokingabetter cigarette: 2 ourprcseneniter only daing halfthejob De4m 1747 0 Hhere snosubsutu Tareyton lights din6rr 1 foz lieyto gIghcs 100-9m12 DeS me LowI Hareyton lighs I Wertv\"cg: The Jurgeon General Ha: Determined mhat Cigarette Smoting |: Dangerotz (0 our Heaith Enon Ion; Enis M; \". 0.6 mG, akjini pa Garule 6y FTC method"
] |
[
[
66,
20,
735,
969
]
] | 4
|
|
754
| 1,000
|
resume
|
[
"___PRINGIPAL",
"INVESTIGATORI@ROGHAM",
"DIRECTOR:",
"BIOGRAPHICAL",
"SKETCH",
"‘ive",
"the",
"following",
"forthe",
"Key",
"personnel",
"and",
"iste",
"on",
"page",
"2.",
"Begin",
"wth",
"the",
"Photocopy",
"this",
"gage",
"foreach",
"person",
"NAME",
"(ito,",
"Day,",
"Cheryl",
"A.",
"Berger,",
"M.D.",
"Professor",
"|",
"July",
"30,",
"1958",
"EDUCATION",
"Bogn",
"win",
"accsove",
"al",
"sui.",
"ad",
"alge",
"ing)",
"INSTITUTION",
"AND",
"LOCATION",
"|",
"TN",
"|",
"|",
"|",
"DePauw",
"University,",
"Greencastle,",
"IN",
"BA",
"|",
"zoology",
"Indiana",
"University",
"School",
"of",
"\\",
"|",
"1984",
"|",
"Medicine",
"Indianapolis,",
"IN",
"|",
"RESEARCH",
"AND",
"PROFESSIONAL",
"EXPERIENCE:",
"wih",
"Yen\"",
"positon,",
"Ist,",
"ot",
"prewavs",
"‘a",
"noners.",
"Include",
"present",
"membership",
"on",
"any",
"Federal",
"Govunmen",
"pubic",
"advisory",
"cmmitee",
"Lit,",
"n",
"late",
"relerences",
"to",
"all"
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[
"___PRINGIPAL INVESTIGATORI@ROGHAM DIRECTOR: BIOGRAPHICAL SKETCH ‘ive the following forthe Key personnel and iste on page 2. Begin wth the Photocopy this gage foreach person NAME (ito, Day, Cheryl A. Berger, M.D. Professor | July 30, 1958 EDUCATION Bogn win accsove al sui. ad alge ing) INSTITUTION AND LOCATION | TN | | | DePauw University, Greencastle, IN BA | zoology Indiana University School of \\ | 1984 | Medicine Indianapolis, IN | RESEARCH AND PROFESSIONAL EXPERIENCE: wih Yen\" positon, Ist, ot prewavs ‘a noners. Include present membership on any Federal Govunmen pubic advisory cmmitee Lit, n late relerences to all during te oat thee years and eater putliesions 1 his EXCEED TWO Pages PROFESSIONAL EXPERIENCE: 1984-1985 Intern in Internal Medicine,: Emanuel Hospital, Portland, OR 1985-1986 Fellow in Dermatology Research, Department of Dermatology, Oregon Health Sciences University, Portland, OR 1986-1989 Resident in Dermatology, Department of Dermatology, Oregon Health Sciences University, Portland, OR 1989- Assisstant Professor of Dermatology, Department of Dermatology, Oregon Health Sciences University/Veterans Administration Medical Center, Portland, OR HONORS & AWARDS: International Science & Engineering Fair, Denver, CO, 1976 National Junior Science & Humanities Symposiun, Washington, DC, 1976 Graduated Magna cum Laude, 1980 Phi Beta Kappa, 1980 Student Resaarch Program in Academic Medicine, 1981-1984 National Research Service Award, Research Fellowship, 1986-1987 #¥ Tartar Trust Fellowship, 1986-1987 Dermatology Foundation Fellowship, 1989-1990 Medical Research Foundation of Oregon Award, 1989-1990 American Cancer Society, Oregon Division Award, 1990-1991 RESEARCH TRAINING: Pharmacology research at Indiana University in Bloomington, Indiana - A study of the effect of parachlorophenylalanine on ethanol consumption in rats, 1975 Ecology research at DePauw University in Greencastle Indiana - A habitat analysis of tributaries of the Eagle Creek Watershed, 1978-1979 Immunology research at Eli Lilly Company in Indianapolis, Indiana - A study of the effect of an experimental drug on T cell function, 1980 Microbiology research at the Indiana University School of. Medicine, Indianapolis, Indiana - A recombinant DNA study of the Mut-D gene in E. coli, 1980 Biochemistry research at the Indiana University School of Medicine, Indianapolis, Indiana - A study of the effect of ultraviolet Light on DNA replication in Simian Virus 40, 1981-1984 PHS 359 (Rev. 1088) (Rearintes S69) Page ee \"Number aie Boom he De ive canna en"
] |
[
[
43,
21,
719,
989
]
] | 14
|
|
779
| 1,000
|
form
|
[
"24",
"s",
"ck"
] |
[
[
750,
301,
773,
329
],
[
762,
334,
773,
359
],
[
746,
361,
772,
386
]
] |
[
"24 s ck"
] |
[
[
746,
301,
773,
386
]
] | 1
|
|
726
| 1,000
|
scientific report
|
[
"172403",
"Review",
"387",
"CONFIDENTIAL",
"of",
"Ty",
"1278:",
"Subject",
"sMarriage",
"to",
"@",
"sacker",
"and",
"tung",
"cancer",
"risk”",
"J.M.Sazee",
"and",
"D.R.Pathak",
"Anerican",
"Journal",
"of",
"Public",
"Health",
"(1967),",
"77,",
"598-602",
"This",
"paper",
"describes",
"che",
"results",
"of",
"a",
"case-control",
"study",
"carried",
"out",
"in",
"New",
"Mexico",
"of",
"the",
"relationship",
"of",
"marriage",
"to",
"a",
"and",
"lung",
"cancer",
"risk.",
"The",
"cases",
"vere",
"patients",
"wich",
"lung",
"cancer",
"incident",
"in",
"1980-82.",
"There",
"were",
"724",
"eligible",
"cases,",
"of",
"which",
"interviews",
"could",
"be",
"carried",
"out",
"for",
"641",
"(305",
"with",
"the",
"cases",
"and",
"336",
"with",
"surrogates),",
"609",
"producing",
"complete",
"data",
"on",
"passive",
"and",
"personal",
"snoking",
"status.",
"The",
"controls",
"were",
"mainly",
"obtained",
"by"
] |
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348,
523,
369,
531
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377,
522,
433,
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442,
522,
491,
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[
500,
524,
547,
531
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[
132,
550,
152,
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[
161,
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217,
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[
225,
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319,
551,
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[
390,
550,
404,
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[
"172403 Review 387 CONFIDENTIAL of Ty 1278: Subject sMarriage to @ sacker and tung cancer risk” J.M.Sazee and D.R.Pathak Anerican Journal of Public Health (1967), 77, 598-602 This paper describes che results of a case-control study carried out in New Mexico of the relationship of marriage to a and lung cancer risk. The cases vere patients wich lung cancer incident in 1980-82. There were 724 eligible cases, of which interviews could be carried out for 641 (305 with the cases and 336 with surrogates), 609 producing complete data on passive and personal snoking status. The controls were mainly obtained by random telephone sampling but for the older age groups (65+) an extra group of people taken from a roster of Medicare participants vas used. Of 944 selected controls, 784 were interviewed and 781 provided complete data No relationship of suoking by the spouse co risk of lung cancer was seen azong subjects who However, among subjects who never having snoked, there vas an estizated 2-3 fold py (depending on the precise analysis) higher risk of lung cancer in = Latter analyses tnvolved 28 lung cancer cases (8 non-exposed, 20%"
] |
[
[
94,
36,
635,
814
]
] | 5
|
|
777
| 1,000
|
presentation
|
[
"fl",
"lm",
"ore",
"fv",
"ApS?!",
"oo",
"ABSTRACT",
"USE",
"OF",
"APHYSIOLOGICALLY-BASED",
"PHARMACOKINETIC",
"(PB-",
"PK)",
"NICOTINE-COTININE",
"MODEL",
"TO",
"ASSESS",
"THE",
"INFLUENCE",
"OF",
"NICOTINE",
"ON",
"THE",
"DISTRIBUTION",
"OF",
"COTININE",
"IN",
"MAN.",
"D.E.",
"Robinson.",
"NV.J.",
"Balterand",
"S.L,",
"Schwartz.",
"Georgetown",
"Univ.",
"Sch.",
"of",
"Med.,",
"Washington,",
"D.C.",
"20007.",
"Data",
"reported",
"from",
"studies",
"in",
"rats",
"suggest",
"that",
"nicotine",
"can",
"affect",
"the",
"volume",
"of",
"distribution",
"(V,)",
"of",
"cotinine.",
"Specifically,",
"Gabrielsson",
"and",
"Bondesson",
"(J.",
"Pharmacokinet.",
"Biopharm.",
"15(6):",
"583-599,",
"1987)",
"reported",
"that",
"tissue-blood",
"partition",
"coefficients",
"for",
"cotinine",
"were",
"2-5",
"times",
"greater",
"for",
"the",
"endogenous",
"cotinine",
"produced",
"following",
"an",
"intravenous",
"infusion",
"of",
"nicotine",
"than",
"when",
"cotinine",
"was",
"infused",
"directly.",
"Based",
"on"
] |
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[
"fl lm ore fv ApS?! oo ABSTRACT USE OF APHYSIOLOGICALLY-BASED PHARMACOKINETIC (PB- PK) NICOTINE-COTININE MODEL TO ASSESS THE INFLUENCE OF NICOTINE ON THE DISTRIBUTION OF COTININE IN MAN. D.E. Robinson. NV.J. Balterand S.L, Schwartz. Georgetown Univ. Sch. of Med., Washington, D.C. 20007. Data reported from studies in rats suggest that nicotine can affect the volume of distribution (V,) of cotinine. Specifically, Gabrielsson and Bondesson (J. Pharmacokinet. Biopharm. 15(6): 583-599, 1987) reported that tissue-blood partition coefficients for cotinine were 2-5 times greater for the endogenous cotinine produced following an intravenous infusion of nicotine than when cotinine was infused directly. Based on known membrane properties of nicotine, the phenomenon would not be surprising and could have implications for the clinical pharmacokinetics of drugs in smokers. We considered whether or not a similar phenomenon occurs in man by applying a PB-PK model for nicotine and cotinine to the pharmacokinetic data collected and previously reported by Curvall et al. (Clin Pharmacol Ther 47(1): 42-49, 1990). Data were available from 4 individuals who had received, at different times, both nicotine and cotinine infusions. For each individual, separate nicotine and cotinine PB-PK models were established, which effectively simulated the individual blood and urine data for nicotine and exogenous cotinine. The 2 models were then linked at the liver compartment to model endogenously-produced cotinine. Data obtained from the simulation output indicated no need to alter the distribution ) parameters for exogenous VS. endogenous cotinine, implying that V, of cotinine was not influenced by nicotine in these subjects. 2 Q B ° a"
] |
[
[
58,
49,
690,
928
]
] | 12
|
|
780
| 1,000
|
letter
|
[
"THE",
"TOBACCO",
"INSTITUTE",
"SORT",
"SAMUEL",
"D.",
"CHILCOTE.",
"October",
"5,",
"1984",
"The",
"Honorable",
"Wendell",
"H.",
"Ford",
"United",
"States",
"Senate",
"Washington,",
"DC",
"20510",
"Dear",
"Wendell:",
"On",
"behalf",
"of",
"the",
"member",
"companies",
"of",
"The",
"Tobacco",
"Institute,",
"I",
"want",
"to",
"thank",
"you",
"for",
"your",
"very",
"special",
"thoughtfulness",
"in",
"joining",
"with",
"Senators",
"Huddleston,",
"Quayle,",
"Helms,",
"East",
"and",
"Trible",
"to",
"forward",
"our",
"\"Helping",
"Youth",
"Decide\"",
"material",
"to",
"other",
"Members",
"on",
"September",
"21.",
"One",
"early",
"result",
"is",
"that",
"several",
"Members",
"have",
"requested",
"substantial",
"numbers",
"of",
"copies",
"to",
"provide",
"to",
"educational",
"authorities",
"in",
"their",
"districts.",
"We",
"have",
"also",
"been",
"encouraged",
"by",
"initial",
"endorsements",
"of",
"the",
"project",
"which",
"we"
] |
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179,
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[
233,
468,
250,
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] |
[
"THE TOBACCO INSTITUTE SORT SAMUEL D. CHILCOTE. October 5, 1984 The Honorable Wendell H. Ford United States Senate Washington, DC 20510 Dear Wendell: On behalf of the member companies of The Tobacco Institute, I want to thank you for your very special thoughtfulness in joining with Senators Huddleston, Quayle, Helms, East and Trible to forward our \"Helping Youth Decide\" material to other Members on September 21. One early result is that several Members have requested substantial numbers of copies to provide to educational authorities in their districts. We have also been encouraged by initial endorsements of the project which we have received from organizations such as the American Association of School Administrators, the National Association of Elementary School Principals, the Institute for Educational Leadership and the Board of Regents of the University of New York. We are convinced that parental guidance as contrasted with public propaganda is the best way to help young teens avoid premature decisions about adult activities. We believe our project will be helpful to parents in this respect and we intend to continue to promote it vigorously. Thank you again for your generous support. Sincerely, Samuel D, Chileote, Jr. TIMN 202280"
] |
[
[
105,
63,
720,
929
]
] | 0
|
|
754
| 1,000
|
presentation
|
[
"FOR",
"IMMEDIATE",
"RELEASE,",
"Contact",
":",
"Dolly",
"Colby",
"212-878-2144",
"POLITICS",
"AS",
"USUAL",
"FOR",
"GIULIANI",
"IN",
"HIS",
"LAWSUIT",
"AGAINST",
"TOBACCO",
"COMPANIES,",
"NEW",
"YORK,",
"Oct.",
"17,",
"1996",
"--",
"Mayor",
"Rudolph",
"Giuliani's",
"decision",
"to",
"file",
"suit",
"against",
"the",
"nation's",
"major",
"tobacco",
"companies",
"is",
"a",
"purely",
"political",
"act",
"that",
"amounts",
"to",
"an",
"unfounded",
"attack",
"on",
"a",
"legal",
"product,",
"Philip",
"Morris,",
"U.S.A.",
"says.",
"By",
"bringing",
"this",
"case,",
"he",
"is",
"following",
"in",
"the",
"footsteps",
"of",
"an",
"unusual",
"assortment",
"of",
"publicity",
"seeking",
"politicians",
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[
"FOR IMMEDIATE RELEASE, Contact : Dolly Colby 212-878-2144 POLITICS AS USUAL FOR GIULIANI IN HIS LAWSUIT AGAINST TOBACCO COMPANIES, NEW YORK, Oct. 17, 1996 -- Mayor Rudolph Giuliani's decision to file suit against the nation's major tobacco companies is a purely political act that amounts to an unfounded attack on a legal product, Philip Morris, U.S.A. says. By bringing this case, he is following in the footsteps of an unusual assortment of publicity seeking politicians and lawyers who believe they can disregard established principles of law and use the to legislate public policy on tobacco. unfortunate that the mayor, a lawyer and former United States Attorney for the Southern District of New York, has ignored the fact that the city has no viable legal basis upon which to sue cigarette manufacturers,\" said Charles R. Wall, deputy general counsel and senior vice president for Philip Mortis. \"We believe itis regrettable that a duly elected official feels so little constraint by law or fact that he willingly jamps on ‘what is perceived by some to be the politically correct bandwagon of tobacco litigation.\" \"This lawsuit is especially ironie because it names as one of the defendants, Philip Mortis, U.S.A, which stood by New York in the troubled days of the 1970s and 1980s when so many major - -more- 8 ig 3 a 8 8"
] |
[
[
115,
143,
664,
846
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|
|
777
| 1,000
|
news article
|
[
"For",
"the",
"T.I.R.C,",
"grants,",
"both",
"general",
"and",
"localized",
"news",
"releases",
"were",
"¢",
"(90244",
"Goo",
"A",
"POST",
"AND",
"TIMES",
"STAR",
"NEW",
"YORK",
"CHICAGO",
"SUN-TIMES",
"Cincinnati,",
"Ohio",
"New",
"York,",
"New",
"York",
"Chicago,",
"Illinois",
"October",
"26,",
"1961",
"October",
"25,",
"1961",
"October",
"23,",
"1961",
"Tobacco",
"Research",
"New",
"Tobacco",
"NU",
"Professor",
"Grants",
"Made",
"Given",
"Tobacco",
"y",
"NEW",
"YORK,",
"Timothy",
"‘Thirty",
"research",
"grants,",
"tot-",
"lartnett,",
"chairman",
"aling",
"over",
"$296,000.",
"to",
"scien-",
"2%",
"tor",
"Research",
"Grant",
"has”",
"announced",
"relating",
"to",
"tobacco",
"use",
"and",
"gran",
"tolling",
"Sennen",
"todos",
"Special",
"0",
"The",
"Sun-Times",
"more",
"than",
"S206",
"000,",
"to",
"inde",
"marine",
"da",
"The",
"Pendent",
"“in",
"dd",
"the",
"states",
"for",
"studies"
] |
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[
"For the T.I.R.C, grants, both general and localized news releases were ¢ (90244 Goo A POST AND TIMES STAR NEW YORK CHICAGO SUN-TIMES Cincinnati, Ohio New York, New York Chicago, Illinois October 26, 1961 October 25, 1961 October 23, 1961 Tobacco Research New Tobacco NU Professor Grants Made Given Tobacco y NEW YORK, Timothy ‘Thirty research grants, tot- lartnett, chairman aling over $296,000. to scien- 2% tor Research Grant has” announced relating to tobacco use and gran tolling Sennen todos Special 0 The Sun-Times more than S206 000, to inde marine da The Pendent “in dd the states for studies relating to Research Committee. Hull, assistant professor of use and health pants mate atts at of the ais ar at ona has been awarded we or new research pojets a tended sents very has een awarded the remainder for continued in some 75 institutions. Ali ch grant fr the Tobage the remainder far made 0p an bear Indy Research. Commitee range “of aid \"Dr af ae Sunday Cook sien \"way aie, The srs Sanday. lufie director of the TIRC. TIRC. has appropriated $4- Hull has been searching for a The committee, Hartnett £650,000 for research to date. sald approptiated a to for fo date, teenie tet that ill oo ths far for tor nes determine the kind aod concen ( he othe traton of eomiusion product \\ for She that in tests have caused 8 BALTIMORE MORNING SUN of subjects according to. D: among mice. \"Te current et takes 61018 Baltimore, Maryland She & October 27, 1961 new ear the & Two Hopkins Doctors test toa few days duration. De. Hulls gant one of 30. Get Tobacco AND SUW research rants. B Tes i York, New York more than 8236000, hat have © Jokes October 25, 1961 been the commitee ER have been trated te f Tobacco-Health Sue fans or Granis Allotted 100% ‘Theirs are among 39 research ‘Thirty grants, 020746 09 & prin 29 research ing Sones eget ave been awarded to independ: grt states tor Towa City, Iowa by, in ind were “announced october 28, 1962 tobacto ute aed health, ete chairman of the ToBAcco Dr. J, Pr Tog of SUI has been awarded a research grant by the com 19 scent Cardiovascular. properties of alee Tone, associate” of one 030 ant heath ."
] |
[
[
29,
40,
748,
917
]
] | 9
|
|
1,000
| 789
|
presentation
|
[
"PHILIP MORRIS",
"1",
"COMPANIES INC:",
"Holt",
"Barry",
"Contact:",
"120 PARK AVENUE , NEW YORK N.Y 10017",
"(212)880-3475",
"FQR IMMEDIATERELEASE",
"1992",
"November",
"counsel for Philip",
"Legal",
"New York, NY",
"informed today",
"Morris",
"were",
"the Cipollone",
"Marc Edell has",
"We",
"voluntarily",
"dismissed",
"have",
"that",
"case",
"to dismiss",
"Mr. Edell",
"informed",
"his",
"co-counsel intend",
"also",
"been",
"that",
"and",
"they",
"smoking",
"cases in New Jersey",
"in which",
"several",
"other",
"and",
"health",
"that they",
"addition,",
"understand",
"will",
"seek",
"have",
"served",
"counsel.",
"we",
"from",
"permission",
"withdraw",
"the",
"from",
"the",
"counsel",
"tWo",
"courts",
"plaintiffs",
"remaining",
"proceed_",
"which",
"wish",
"cases",
"the",
"####",
"1",
"BensongHecges",
"Marlboro ,",
"Merit / } Virginia Slims",
"Lighis",
"Pariameni",
"Apine",
"Petor Jackson",
"Ph lip Mcrris Supor Lighls",
"Lam",
"Chesterfield",
"Kralt ( ? Miracle Whip",
"velveeta",
"ulurall Amjussadar",
"Sealtest",
"Fruson Gladic .",
"Parkay",
"Phlladelphia Brand",
"Lightn' Lively",
"Cneezwniz |",
"Brearstono",
"Cracke",
"Barre",
"3ieyens",
"Oscar",
"Mayot",
"Jello",
"Entenmann",
"6ve",
"Houso",
"Bucge",
"Kool-Aid",
"Post cereals",
"Santa",
"Birds",
"Gourmnei",
"Lender'$",
"Maxtell",
"chewing gum",
"Suchard cotfees and chocolale",
"Kiban",
"Hollcood",
"Louis Rich",
"Jacobs",
"Jcsscnts",
"Cream",
"Laxenbnam",
"Weister Briiu (! Mihwauked * Best",
"Simmenthal prccessud mcal and IIsh ,",
"Miiler High Lile .",
"Miller Genuine Oralt",
"Hiller Lite"
] |
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[
"1 PHILIP MORRIS COMPANIES INC: 120 PARK AVENUE , NEW YORK N.Y 10017",
"Barry Holt (212)880-3475",
"Contact:",
"FQR IMMEDIATERELEASE November 1992",
"New York, NY Legal counsel for Philip Morris were informed today that Marc Edell has voluntarily dismissed the Cipollone case We have also been informed that Mr. Edell and his co-counsel intend to dismiss several other smoking and health cases in New Jersey in which they have served counsel. addition, we understand that they will seek",
"counsel from the tWo",
"permission from the courts",
"withdraw which the plaintiffs wish",
"remaining cases",
"proceed_",
"####",
"1 Marlboro , BensongHecges Merit / } Virginia Slims Pariameni Lighis Apine Petor Jackson Ph lip Mcrris Supor Lighls ulurall Amjussadar Lam Chesterfield Kralt ( ? Miracle Whip velveeta Phlladelphia Brand Cneezwniz | Lightn' Lively Brearstono Cracke Barre 3ieyens Sealtest Fruson Gladic . Parkay Maxtell Houso Santa Kool-Aid Birds 6ve Bucge Gourmnei Lender'$ Post cereals Jello Entenmann Oscar Mayot Louis Rich Jacobs Suchard cotfees and chocolale Jcsscnts Kiban Cream Hollcood chewing gum Simmenthal prccessud mcal and IIsh , Miiler High Lile . Miller Genuine Oralt Hiller Lite Laxenbnam Weister Briiu (! Mihwauked * Best"
] |
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|
1,000
| 754
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presentation
|
[
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"{ 1 8 J | 1"
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319,
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|
|
1,000
| 773
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specification
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|
|
754
| 1,000
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scientific report
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[
"a DEFINITION DER ZEICHNUNG NR. 995 ERSTELLER DATUM re PRU THO 8 KURZTITEL: LUNGS. END OF INHALATION PERTOD BEMERKUNG: AHM (NMOL S-OH-B(A)P/(G PROT. X H)) DEFINITION OER GRUPPEN (BALKEN) ZU ZEICHNUNGS-NR. 995 1.88 KEINE SCHRAFFUR se DATEN 2U ZETCHNUNGS-NR. 995 x y z FEHLERBALKEN star. NR. UNTERER syne. RANGEWERT RANGEWERT 1.22 13.0008 4.0098 88 2 13 22.0088 — V1. Rew 3"
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[
[
42,
84,
721,
831
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] | 5
|
|
754
| 1,000
|
presentation
|
[
"TUE",
"01282",
"AM",
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"Circuit",
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"John",
"R.",
"Weber",
"struck",
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"“has",
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"establishments.”",
"Weber",
"h",
"‘hat",
"only",
"state",
"law",
"—",
"not",
"local",
"ordinances",
"—",
"can",
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[
"TUE 01282 AM arias sae RESTAURANT . ASSOCIATION _ Promating in Hospitaty sings 1921 FOR IMMEDIATE RELEASE CONTACT: Rob Gifford Thursday, Jan. 7, 2999 G17) 482-5244 Judge Throws Out Marquette’s Ban On Smoking In Restaurants © MARQUETTE, Mich. — Six restaurant owners and tha Michigan Rastaurant Associatic (MRA) today won a lawsuit against the City of Marquette’s ban on smoking in Marquetta Circuit Judge John R. Weber struck down the ordinance, ruling that @) Marquette “has no power to regulate smoking in food service establishments.” Weber h ‘hat only state law — not local ordinances — can regulate amoking in Michigan restaurants, “Michigan restaurant owners are concemed about the public health of our customats, and that's why we support the enisting state law — part of the Public Health Code — that regulates smoking in restaurants,” sald MRA Executive Director Rab “Our position was that local units of government can't overstep state law, and the judge strongly agreed.” The ordinance in question was amended by the City of Marquette in 1997 to ban ® smoking in all city restaurants effective Jan. 1, 1999, Tha Michigan Restaurant Ascociatio and six of its restaurants filed suit against the city in December 1998. Restaurants are required by the state’s Public Health Code (Section 339.12905 (2) to Seserve a percentage of their seating space for non-smokers. A restaurant with fewer than 90 sents must designate at least 25 percent ofits neating for A wit ‘more than $0 seats must designate at least half ofits seating eapacity for non-smokers, More 2064996678"
] |
[
[
70,
85,
715,
868
]
] | 12
|
|
754
| 1,000
|
memo
|
[
"3",
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"INC.",
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"gS",
"120",
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"11,",
"1999",
">",
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"Francisco",
"was",
"wrong.",
"Second,",
"the",
"punitive",
"damage",
"award",
"of",
"$50",
"million",
"is",
"outrageous.",
"Right-minded",
"people",
"inside",
"and",
"outside",
"our",
"company",
"will",
"find",
"it",
"apparent",
"that",
"this",
"jury",
"could",
"not",
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"fact",
"and",
"logic",
"from",
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"and",
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"will",
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[
"3 PHILIP MORRIS INC. INTER-OFFICE CORRESPONDENCE gS 120 PARK AVENUE, NEW YORK, NY 10017-5592 TO: All Employees DATE: February 11, 1999 > FROM: Geoffrey C. Bible SUBJECT: Punitive D: in the I. First, let me make very clear that I am absolute in my belief that the jury verdict in San Francisco was wrong. Second, the punitive damage award of $50 million is outrageous. Right-minded people inside and outside our company will find it apparent that this jury could not separate fact and logic from prejudice and emotion. We will mount a vigorous appeal and both the punitive damages award and the compensatory damage award should be reversed. I regret that our employees must once again cope with a difficult situation. You have shown your mettle in the past and I have no doubt you will do so this time as well. But make no mistake about it. We will do everything in our power to reverse the verdict and the punitive damage award. Our day-to-day work will go forward without interruption or pause, Let me assure you we are already marshaling our forces in preparation for the appeal."
] |
[
[
57,
123,
713,
576
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] | 15
|
|
759
| 1,000
|
specification
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77,
63,
688,
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|
777
| 1,000
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file folder
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"= + = = > ! xX i | » j o i = ‘| \\ |"
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[
[
357,
203,
699,
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] | 8
|
|
783
| 1,000
|
handwritten
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[
[
33,
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|
|
754
| 1,000
|
resume
|
[
"a",
"Appendix",
"12",
"CURRICULUM",
"VITAE",
"Edward",
"Charles",
"Pequignot",
"vow",
"Personal",
"Information",
"&",
"January",
"20,",
"1952",
"Marital",
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"Excellent",
"Address:",
"5450",
"Wissahickon",
"Avenue",
"Philadelphia,",
"Pennsylvania",
"19144",
"Phone:",
"(215)",
"848-7386",
"1970-1",
"Clarkson",
"College",
"of",
"Technology,",
"Potsdam,",
"N.Y.",
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"Civil",
"Engineering",
"1971-75",
"State",
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"of",
"New",
"York",
"at",
"Buffalo",
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"B.A.",
"in",
"Statistics",
"1975-76",
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"New",
"York",
"at",
"Buffalo",
"Major:",
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"Science",
"Degree:",
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"Honors",
"Menber",
"of",
"Phi",
"Beta",
"Kappa",
"and",
"Pi",
"Mu",
"Epsilon",
"Graduated",
"Sunma",
"Cun",
"Laude,",
"May",
"1975",
"|",
"Relevant",
"Courses",
"Statistical",
"Computing",
"Techniques",
"Stochastic",
"Processes",
"Probability",
"Theory",
"Time",
"Series",
"Analyois",
"Sampling",
"Theory",
"Contingency"
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[
"a Appendix 12 CURRICULUM VITAE Edward Charles Pequignot vow Personal Information & January 20, 1952 Marital Status: Single Health: Excellent Address: 5450 Wissahickon Avenue Philadelphia, Pennsylvania 19144 Phone: (215) 848-7386 1970-1 Clarkson College of Technology, Potsdam, N.Y. Major: Civil Engineering 1971-75 State University of New York at Buffalo Degrees: B.S. in Mathematics, B.A. in Statistics 1975-76 State University of New York at Buffalo Major: Statistical Science Degree: M.S. Honors Menber of Phi Beta Kappa and Pi Mu Epsilon Graduated Sunma Cun Laude, May 1975 | Relevant Courses Statistical Computing Techniques Stochastic Processes Probability Theory Time Series Analyois Sampling Theory Contingency Table Analysis Regression Analysis Biometry Design of Experiments Professional Experience 1977-1982 Senior Instructor, Statistician, Data Manager, and Computer Progranmer for Department of Hematology and Medical Oncology, University. 1979-1983 Instructor for basic statistics course for Hematology and Oncology Fellows, Department of Hematology and Medical Oncology, Hohnemann University. 50222975"
] |
[
[
10,
22,
732,
997
]
] | 14
|
|
754
| 1,000
|
handwritten
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[
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"HE",
"fan",
"a",
"em",
"Ca",
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"al",
"ae!",
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[
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[
[
30,
25,
667,
860
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] | 3
|
|
777
| 1,000
|
scientific report
|
[
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"PROJECT",
":",
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">",
"PERIOD",
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":",
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"-",
"February",
"24th,",
"1981",
"WRITTEN",
"BY",
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"|",
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"3 | 4 a PROJECT : PLANT OPERATIONS > PERIOD COVERED : January 27th - February 24th, 1981 WRITTEN BY ON, | le EQUIPMENT 1.1, Extraction Line for stems a on January 26th, a decision was taken not to carry out further @ trials with stems at the present time (Ref. 1). i Therefore the extraction line for stems comprising equipment such as a V-shaped extractor, a feeder and a roller was | Gisnounted and the rotocell extractor was installed in its place. The parts were cleaned, overhauled and sent to the FIR warehouse. 1.2. Rotocell extractor ‘This installation was put in place ready for use in the extraction of RL which is part of NINO trial 67 (Ref. 2). In addition, the outlet of the rotocell extractor was connected FS to the inlet of the dryer by means of two vibrating conveyors. This link enables continuous pre-drying of the extracted material. The final drying is still carriea out batch by batch with the make-shift dryer. The FIR engineering department has started work on the construction of the continuous feeding system for the rotocell extractor. i 2 MISCELLANEOUS | About 1000 kg of a European RL blend were prepared for NINO | trial 67 (Ref. 2). | REFERENCES | Ref, 1: \"Minutes of meoting to discuss future denitration trials\", | a January 26th, 1981, C. Ruf Ref, Monthly report, February 1981, \"Nitrate Reduction by | Controlled C. Ruf. x 3 5 | Rarch 2nd, 1981 - / A de Wha. 8 lu 8 @ x a"
] |
[
[
12,
41,
721,
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|
754
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resume
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"less,",
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"pertinent",
"publications.",
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[
"Principal Investigator, David A. Brown BIOGRAPHICAL SKETCH David A. Brown Principal Investigator NAME ROLE IN PROJECT EDUCATION. Begin with most recent, Including postdoctoral training, and end with baccalaureate, Institution and Location Field of Study Degree Year University of British Marine Toxicology Ph.D. 1979 Columbia, Vancouver, Conade University of British Biochenistry B.Sc. 1970 Colunbia, Vancouver, Canada RCH AND PI ONAL EXPI . Starting with current or most recent, list: (1) Al professional postions, Including ttle, and years of (2) Complete of all publications in the last 5 years oF less, and earlier pertinent publications. List all authors in order. if Investigator published under another name, underline that name. DO NOT EXCEED TWO PAGES. 3991 ~ present, The Scripps Research Institute, La Jolla, CA, Senior Research Associate 1988 - 1991, City of Hope, Duarte, CA, Research Fellow 1987 - 1988, University of Southern California, Los Angeles, CA, Research Fellow 1980 - 1987, Southern California Coastal Water Research Project, Long Beach, CA., Senior Environmental Specialist 1979 - 1980, Seakem Oceangraphy, Sidney, B.C., Canada, Postdoctoral Fellow 1970 - 1975, British Columbia Research, Vancouver, Canada, Research Officer I PUBLICATIONS: (from a total of thirty-six) Brown, D.A., K.L. Kondo, D.J. Diamond. 1992. Characterization of protein binding to, the regulatory region of interferon in quiescent and activated husan T-cells. Eur. J. Ysmunol. (in press). D.A., Nelson, Esk. Reiaherz, and D.J. Diamond. 1991. The human TFNY gene contains an inducible promoter that can be trensactivated by tax I and II. Eur. J. Immunol. 21:1879-1885. Brown, D.A., S.M. Bay, and G.P. Hershelman. 1990, Exposure of scorpionfish (Scorpaena guttata) to caduiua: effects of acute and chronic exposures on the cytosolic distri- of cadmium, copper and zinc. Aquate. Toxicol. 16:295-310. Bay, S.M., D.J. Greenstein, P. Szalay, and D.A. 1990. Exposure of scorpionfish (Scorpaena guttata) to cedeiua: biochemical effects of chronic exposure. Aquat. Toxicol. 16:311-320. Brown, Bay, D.J. Greenstein, P. G.P. Hershelman, C.G. Ward, A.M. Westcott, and J.N. Cross. 1967. Municipal wastewater contamination in the southern California bight: Part 2 - cytosolic distribution of contaminants and biochenical effects in fish livers. Mar. Environ. Res. 21:135-161. 50604512"
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|
754
| 1,000
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specification
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74,
117,
680,
935
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|
|
1,000
| 754
|
form
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"[nscrt name and title] of [insert company name] (the \"Company hcreby certifes in rcspect of the Company $ attached product class list of additives that:",
"All additives which bave been or will be used in tobacco in tle Company' s brands in the product class for sale in New Zcaland havc bcen listed",
"The Company has not included in the list any additive which was not Or will not be used in its brands in the projuct , class for sale in New Zealand.",
"No additive has been Or will be used in the product class in excess of the \"Quantity not excceded\" a8 specified in the Company' list for that product class.",
"DATED this",
"day of",
"2000.",
"DRAIFT",
"[Insert name]",
"1"
] |
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643,
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|
|
1,000
| 873
|
specification
|
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[
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|
|
1,000
| 792
|
specification
|
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391,
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[
"3 5 - /0 B&",
"NSC FOR SAMPLF OROCR",
"5-1088",
"or",
"PAGF 08/10/92",
"*3# NATERTAL SaFFTY Vata SEFT *8X",
"National Svarn and Cnemical Company Finderne Avenue P.0+ Box 6500 Bridsewa tet' NJ 08807 Corporate #nri eme Xency epnone 908-685-5000",
"pRntuct TdfnttFtcatton",
"PROOUGT NUMPER PRODUCT NAME CHEMICAL. Famtl",
"25- 038 RESYN QRR Vinyl Acet?te Homopo YM",
"cmposittonytnFormatton WN tnGReD(ENTS",
"INOREDTENT NANE/ca; Nutder/prRGEnTAGE",
"EXPOSIRE LIMITS",
"Vinvl Acetake Resiuual Monmner CAS NUMDER 108-05-4 PERCENTAGE <0",
"nsho , AcGii STEL. CEIL'",
"9#m 10 #XI 20 PRm Not notod",
"FhysTCAL DatA",
"PURF MatFRIAi. OR MIXTURE. Physicm ORT APPEARANCE/PHYSTCAL UcSRITION- PH As [S DOIL InG-PdINT MELTINQ/FREEZING PQNT SOLUBILI- WATER< SPRCIFTC GRAVTTY (WAteR BULK DENSITY VoL.ATTLES APDRRPTEGN PTEONURATEmmhs; VAPOR DENSITY (AIR 1 ) VIScOSITY",
"Mixture Liquid Milk while RUPUU: Pmulsiony SWeFt odur 4+5 717 32 M;scinle 030 1tcla?l 527 (watet 1 al zo\" 0,62 950 cps"
] |
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25,
781,
65
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109
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[
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[
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[
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[
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],
[
41,
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[
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[
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],
[
37,
719,
331,
931
],
[
353,
719,
757,
946
]
] | 7
|
|
754
| 1,000
|
resume
|
[
"Biographical",
"Sketch:",
"William",
"Hendrickson",
"Department",
"of",
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"&",
"Immunology",
"Telephone:",
"312-996-5600",
"University",
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"at",
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"312-996-6415",
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"Medicine",
"835",
"S,",
"Wolcott",
"Chicago,",
"Il",
"60612",
"Education",
"1969-1973:",
"B.S.",
"(Honors);",
"Indiana",
"University:",
"Major:",
"Biology",
"1973-1981:",
"Ph.D.",
"Tufts",
"Med.",
"School,",
"Boston,",
"MA;",
"Mol.",
"&",
"Microbiology",
"1981-1985:",
"Postdoctoral;",
"Brandeis",
"University,",
"Waltham,",
"MA",
"Professional",
"history",
"1991-present:",
"Professor,",
"Department",
"of",
"Microbiology",
"and",
"Immunology,",
"University",
"of",
"Illinois",
"at",
"Chicago,",
"College",
"of",
"Medicine,",
"Chicago,",
"Il.",
"1985-1990:",
"Assistant",
"Professor,",
"Department",
"of",
"Microbiology,",
"The",
"Pennsylvania",
"State",
"University,",
"College",
"of",
"Medicine,",
"Hershey,",
"Pennsylvania",
"1981-1985:",
"Postdoctoral",
"Research,",
"Department",
"of",
"Biochemistry,",
"Brandeis",
"University,",
"Waltham,",
"Massachusetts",
"Laboratory",
"of",
"Dr.",
"Robert",
"Schleif"
] |
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[
"Biographical Sketch: William Hendrickson Department of Microbiology & Immunology Telephone: 312-996-5600 University of Illinois at Chicago Pax: 312-996-6415 College of Medicine 835 S, Wolcott Chicago, Il 60612 Education 1969-1973: B.S. (Honors); Indiana University: Major: Biology 1973-1981: Ph.D. Tufts Med. School, Boston, MA; Mol. & Microbiology 1981-1985: Postdoctoral; Brandeis University, Waltham, MA Professional history 1991-present: Professor, Department of Microbiology and Immunology, University of Illinois at Chicago, College of Medicine, Chicago, Il. 1985-1990: Assistant Professor, Department of Microbiology, The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania 1981-1985: Postdoctoral Research, Department of Biochemistry, Brandeis University, Waltham, Massachusetts Laboratory of Dr. Robert Schleif Professional Societies: American Society of Microbiology American Association for the Advancement of Science Publications: LAbe, M., Hendrickson, W. G., Boyd, D., Clifford, P., Cote, R. and Schaechter, The release of coli DNA from membrane complexes by single- strand endonucleases. Proc. Natl. Acad. Sci., 74: 2756-2760, 1977. 2.Nagai, K., Hendrickson, W. G., Balakrishnan, R., Yamaki, H. Boyd, D., and Schaechter, M. Isolation of a replication origin complex from Escherichia coli. Proc. Natl. Acad. Sci. USA 77: 262-266, 1980, 3.Hendrickson, W. G., Yamaki, H., Murchie, J., King, M., Boyd, D. and Schaechter, M. Specific binding of Escherichia coli replicative origin DNA to membrane preparations. In: Initiation of DNA replication (D. Ray, ed.), Academic Press, New York, 1981. W.G., Kusano, T., Yamaki, H., Balakrishnan, R, King, M. Murchie, J. and Schachter M. Binding of the origin of replication of Escherichia coli to the outer membrane. Cell, 30: 915-923, 1982. 5.Kusano, T,, Steinmetz, D., Hendrickson, W. G., Murchie, J., King, M \"50635809"
] |
[
[
79,
89,
649,
997
]
] | 14
|
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