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---
license: mit
configs:
- config_name: dataset
data_files: "dataset.csv"
---
### Description
This dataset contains signle site mutation of protein DLG4_RAT amino acid sequence and the correspond mutation effect score from a deep mutation scanning experiment.
**Protein Format:** AA sequence
### Splits
traing: 1325
valid: 159
test: 176
### Related paper
The dataset is from [Deep generative models of genetic variation capture the effects of mutations](https://www.nature.com/articles/s41592-018-0138-4).
### Label
Label means fitness score of each mutant amino acid sequence based on a deep mutation scanning experiment.
The effect of each mutation is expressed as the log frequency of observing each amino acid x at each position i in the selected versus the unselected population,
relative to wild type. Ranging from negative infinity to positive infinity. If the effect larger than 0 represents high fitness, smaller than 0 represents low fitness. |