---
license: mit
configs:
- config_name: dataset
  data_files: "dataset.csv"
---

### Description
This dataset contains signle site mutation of protein DLG4_RAT amino acid sequence and the correspond mutation effect score from a deep mutation scanning experiment.

**Protein Format:** AA sequence 

### Splits
traing: 1325

valid: 159

test: 176

### Related paper 
The dataset is from [Deep generative models of genetic variation capture the effects of mutations](https://www.nature.com/articles/s41592-018-0138-4).

### Label
Label means fitness score of each mutant amino acid sequence based on a deep mutation scanning experiment. 
The effect of each mutation is expressed as the log frequency of observing each amino acid x at each position i in the selected versus the unselected population, 
relative to wild type. Ranging from negative infinity to positive infinity. If the effect larger than 0 represents high fitness, smaller than 0 represents low fitness.