---
license: cc-by-4.0
tags:
- biology
- rna
- genomics
---
# Overview

Gene Ontology (GO) is a database of gene-level functional annotations. This specific dataset collects the biological process and activities of specific genes. The GO exists as a heirarchy, and we subset to GO terms at most 3 levels away from the biological process root.

This dataset is redistributed as part of mRNABench: https://github.com/morrislab/mRNABench

# Data Format

Description of data columns:
- `target`: Multihot label indicating GO terms applicable to transcript.  
  The label positions correspond to: `["GO:0007267": 0, "GO:0009410": 1, "GO:0001666": 2, "GO:0007186": 3, "GO:0016477": 4, "GO:0035556": 5, "GO:0007204": 6, "GO:0001525": 7, "GO:0098609": 8, "GO:0000226": 9, "GO:0007166": 10, "GO:0006897": 11, "GO:0030154": 12, "GO:0007283": 13, "GO:0045087": 14, "GO:0030036": 15, "GO:0006914": 16, "GO:0008360": 17, "GO:0000278": 18, "GO:0002250": 19]`
- `cds`: Binary track which reports position of first nucleotide in each codon in CDS.
- `splice`: Binary track which reports position of the 3' end of each exon, indicating splice sites.

# Data Source
This dataset is processed using data collected in the [Gene Ontology Resource](https://geneontology.org/), which is licensed under the Creative Commons Attribution 4.0 Unported License.

Original papers:
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3037419/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10158837/pdf/iyad031.pdf
  
Original dataset source: https://geneontology.org/docs/download-go-annotations/  
Citations:
- Ashburner et al. Gene ontology: tool for the unification of biology. Nat Genet. 2000 May;25(1):25-9. DOI: 10.1038/75556
- The Gene Ontology Consortium. The Gene Ontology knowledgebase in 2023. Genetics. 2023 May 4;224(1):iyad031. DOI: 10.1093/genetics/iyad031