scifact.jsonl

{"query_id": 907, "query": "PGE 2 promotes intestinal tumor growth by altering the expression of tumor suppressing and DNA repair genes."}
{"query_id": 350, "query": "Discrimination between the initiator and elongation tRNAs depends on the translation initiation factor IF3."}
{"query_id": 230, "query": "Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink less that non-carries."}
{"query_id": 593, "query": "Incidence of heart failure decreased by 10% in women since 1979."}
{"query_id": 1216, "query": "The extracellular domain of TMEM27 is cleaved in human beta cells."}
{"query_id": 1337, "query": "Ubiquitin ligase UBC13 generates a K63-linked polyubiquitin moiety at PCNA K164."}
{"query_id": 232, "query": "Cataract and trachoma are the primary cause of blindness in Southern Sudan."}
{"query_id": 1336, "query": "UCB T cells reduce TCR diversity after transplantation."}
{"query_id": 233, "query": "Cell autonomous sex determination in somatic cells does not occur in Galliformes."}
{"query_id": 354, "query": "Downregulation and mislocalization of Scribble prevents cell transformation and mammary tumorigenesis."}
{"query_id": 475, "query": "Glycolysis is one of the primary glycometabolic pathways in cells."}
{"query_id": 113, "query": "Angiotensin converting enzyme inhibitors are associated with increased risk for functional renal insufficiency."}
{"query_id": 1335, "query": "UCB T cells maintain high TCR diversity after transplantation."}
{"query_id": 597, "query": "Incidence rates of cervical cancer have decreased."}
{"query_id": 1213, "query": "The deregulated and prolonged activation of monocytes has deleterious effects in inflammatory diseases."}
{"query_id": 598, "query": "Incidence rates of cervical cancer have increased due to nationwide screening programs based primarily on cytology to detect uterine cervical cancer."}
{"query_id": 115, "query": "Anthrax spores can be disposed of easily after they are dispersed."}
{"query_id": 236, "query": "Cell autonomous sex determination in somatic cells occurs in Passeriformes."}
{"query_id": 478, "query": "Golli-deficient T-cells prefer to differentiate into an anergic phenotype in the adaptive immune response when there are increased levels of Ca2+ in the cytosol."}
{"query_id": 1332, "query": "Tumor necrosis factor alpha (TNF-\u03b1) and interleukin-1 (IL-1) are pro-inflammatory cytokines that inhibit IL-6 and IL-10."}
{"query_id": 237, "query": "Cells lacking clpC have a defect in sporulation efficiency in Bacillus subtilis."}
{"query_id": 238, "query": "Cells undergoing methionine restriction may activate miRNAs."}
{"query_id": 118, "query": "Antibiotic induced alterations in the gut microbiome reduce resistance against Clostridium difficile"}
{"query_id": 239, "query": "Cellular aging closely links to an older appearance."}
{"query_id": 911, "query": "PKG-la plays an essential role in expression of pain hypersensitivity in PGK-la knockout mice."}
{"query_id": 913, "query": "PPAR-RXRs are inhibited by PPAR ligands."}
{"query_id": 914, "query": "PPAR-RXRs can be activated by PPAR ligands."}
{"query_id": 1339, "query": "Ultrasound guidance significantly raises the number of traumatic procedures when attempting needle insertion."}
{"query_id": 13, "query": "5% of perinatal mortality is due to low birth weight."}
{"query_id": 1110, "query": "Suboptimal nutrition is not predictive of chronic disease"}
{"query_id": 1352, "query": "Upregulation of mosGCTL-1 is induced upon infection with West Nile virus."}
{"query_id": 362, "query": "During the primary early antibody response activated B cells migrate toward the inner-and outer paracortical areas where oxysterol accumulation is generated by stromal cells."}
{"query_id": 1107, "query": "Subcutaneous fat depots undergo extensive browning processes after cold exposure."}
{"query_id": 1, "query": "0-dimensional biomaterials show inductive properties."}
{"query_id": 1226, "query": "The loss of the TET protein functions may have dire biological consequences, such as myeloid cancers."}
{"query_id": 1104, "query": "Stroke patients with prior use of direct oral anticoagulants have a lower risk of in-hospital mortality than stroke patients with prior use of warfarin."}
{"query_id": 1225, "query": "The locus rs647161 is associated with colorectal carcinoma."}
{"query_id": 124, "query": "Antiretroviral therapy reduces rates of tuberculosis across a broad range of CD4 strata."}
{"query_id": 3, "query": "1,000 genomes project enables mapping of genetic sequence variation consisting of rare variants with larger penetrance effects than common variants."}
{"query_id": 1344, "query": "Up-regulation of the p53 pathway and related molecular events casues cancer resistance and results in a significantly shortened lifespan marked by senescent cells and accelerated organismal aging."}
{"query_id": 5, "query": "1/2000 in UK have abnormal PrP positivity."}
{"query_id": 127, "query": "Arginine 90 in p150n is important for interaction with EB1."}
{"query_id": 248, "query": "Chenodeosycholic acid treatment increases whole-body energy expenditure."}
{"query_id": 1100, "query": "Statins increase blood cholesterol."}
{"query_id": 1221, "query": "The genomic aberrations found in matasteses are very similar to those found in the primary tumor."}
{"query_id": 128, "query": "Arterioles have a larger lumen diameter than venules."}
{"query_id": 249, "query": "Chenodeosycholic acid treatment reduces whole-body energy expenditure."}
{"query_id": 129, "query": "Articles published in open access format are less likely to be cited than traditional journals."}
{"query_id": 800, "query": "Modifying the epigenome in the brain affects the normal human aging process by affecting certain genes related to neurogenesis."}
{"query_id": 921, "query": "Participating in six months of physical activity improves cognitive functioning."}
{"query_id": 922, "query": "Patients in stable partnerships have a faster progression from HIV to AIDS."}
{"query_id": 805, "query": "Monoclonal antibody targeting of N-cadherin inhibits metastasis."}
{"query_id": 808, "query": "Most termination events in Okazaki fragments are sequence specific."}
{"query_id": 1121, "query": "Synaptic activity enhances local release of brain derived neurotrophic factor from postsynaptic dendrites."}
{"query_id": 1363, "query": "Venules have a thinner or absent smooth layer compared to arterioles."}
{"query_id": 1241, "query": "The myocardial lineage develops from cardiac progenitors of mesodermal origin."}
{"query_id": 1362, "query": "Venules have a larger lumen diameter than arterioles."}
{"query_id": 491, "query": "HNF4A mutations can cause diabetes in mutant carriers by the age of 14 years"}
{"query_id": 130, "query": "Articles published in open access format are more likely to be cited than traditional journals."}
{"query_id": 132, "query": "Aspirin inhibits the production of PGE2."}
{"query_id": 133, "query": "Assembly of invadopodia is triggered by focal generation of phosphatidylinositol-3,4-biphosphate and the activation of the nonreceptor tyrosine kinase Src."}
{"query_id": 1359, "query": "Varenicline monotherapy is more effective after 12 weeks of treatment compared to combination nicotine replacement therapies with varenicline or bupropion."}
{"query_id": 137, "query": "Asymptomatic visual impairment screening in elderly populations does not lead to improved vision."}
{"query_id": 1232, "query": "The minor G allele of FOXO3 is related to more severe symptoms of Crohn's Disease."}
{"query_id": 811, "query": "Mutant mice lacking SVCT2 have greatly increased ascorbic acid levels in both brain and adrenals."}
{"query_id": 814, "query": "Mutations in G-Beta protein GNB2 are present in many cancers, resulting in loss of interaction with G-alpha subunits and concomitant activation of AKT pathway."}
{"query_id": 936, "query": "Peroxynitrite is required for nitration of TCR/CD8."}
{"query_id": 36, "query": "A deficiency of vitamin B12 increases blood levels of homocysteine."}
{"query_id": 1132, "query": "TCR/CD3 microdomains are a required to induce the immunologic synapse to activate T cells."}
{"query_id": 1130, "query": "T regulatory cells (tTregs) lacking \u03b1v\u03b28 are more adept at suppressing pathogenic T-cell responses during active inflammation."}
{"query_id": 380, "query": "Enhanced early production of inflammatory chemokines improves viral control in the lung."}
{"query_id": 1370, "query": "Vitamin D deficiency is unrelated to birth weight."}
{"query_id": 261, "query": "Chronic aerobic exercise alters endothelial function, improving vasodilating mechanisms mediated by NO."}
{"query_id": 141, "query": "Auditory entrainment is strengthened when people see congruent visual and auditory information."}
{"query_id": 142, "query": "Autologous transplantation of mesenchymal stem cells causes a higher rate of opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies."}
{"query_id": 384, "query": "Epidemiological disease burden from noncommunicable diseases is more prevalent in low economic settings."}
{"query_id": 143, "query": "Autologous transplantation of mesenchymal stem cells causes fewer opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies."}
{"query_id": 385, "query": "Epigenetic modulating agents (EMAs) modulate antitumor immune response in a cancer model system."}
{"query_id": 386, "query": "Errors in peripheral IV drug administration are most common during bolus administration and multiple-step medicine preparations."}
{"query_id": 1368, "query": "Vitamin D deficiency effects the term of delivery."}
{"query_id": 146, "query": "Autologous transplantation of mesenchymal stem cells has lower rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies."}
{"query_id": 388, "query": "Ethanol stress decreases the expression of IBP in bacteria."}
{"query_id": 268, "query": "Cold exposure increases BAT recruitment."}
{"query_id": 1245, "query": "The one-child policy has been successful in lowering population growth."}
{"query_id": 148, "query": "Autophagy declines in aged organisms."}
{"query_id": 269, "query": "Cold exposure reduces BAT recruitment."}
{"query_id": 820, "query": "N-terminal cleavage increases success identifying transcription start sites."}
{"query_id": 700, "query": "Localization of PIN1 in the Arabidopsis embryo does not require VPS9a"}
{"query_id": 821, "query": "N-terminal cleavage reduces success identifying transcription start sites."}
{"query_id": 702, "query": "Localization of PIN1 in the roots of Arabidopsis does not require VPS9a"}
{"query_id": 823, "query": "N348I mutations cause resistance to zidovudine (AZT)."}
{"query_id": 42, "query": "A high microerythrocyte count raises vulnerability to severe anemia in homozygous alpha (+)- thalassemia trait subjects."}
{"query_id": 48, "query": "A total of 1,000 people in the UK are asymptomatic carriers of vCJD infection."}
{"query_id": 49, "query": "ADAR1 binds to Dicer to cleave pre-miRNA."}
{"query_id": 1385, "query": "cSMAC formation enhances weak ligand signalling."}
{"query_id": 1021, "query": "Rapid up-regulation and higher basal expression of interferon-induced genes reduce survival of granule cell neurons that are infected by West Nile virus."}
{"query_id": 1020, "query": "Rapid up-regulation and higher basal expression of interferon-induced genes increase survival of granule cell neurons that are infected by West Nile virus."}
{"query_id": 1262, "query": "The repair of Cas9-induced double strand breaks in human DNA is error-prone."}
{"query_id": 1140, "query": "Taking 400mg of \u03b1-tocopheryl acetate helps to prevent prostate cancer."}
{"query_id": 1382, "query": "aPKCz causes tumour enhancement by affecting glutamine metabolism."}
{"query_id": 274, "query": "Combination nicotine replacement therapies with varenicline or bupropion lead to significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy."}
{"query_id": 1019, "query": "Rapid phosphotransfer rates govern fidelity in two component systems"}
{"query_id": 275, "query": "Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is effective at treating KRAS mutant tumors."}
{"query_id": 1259, "query": "The relationship between a breast cancer patient's capacity to metabolize tamoxifen and treatment outcome is dependent on the patient's genetic make-up."}
{"query_id": 1137, "query": "TNFAIP3 is a tumor suppressor in glioblastoma."}
{"query_id": 1379, "query": "Women with a higher birth weight are more likely to develop breast cancer later in life."}
{"query_id": 399, "query": "Exposure to fine particulate air pollution is relate to anxiety prevalence."}
{"query_id": 279, "query": "Commelina yellow mottle virus' (ComYMV) genome consists of 7489 baise pairs."}
{"query_id": 1014, "query": "Rapamycin decreases the concentration of triacylglycerols in fruit flies."}
{"query_id": 830, "query": "NF2 (Merlin) causes phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila by activating LATS1/2 kinases."}
{"query_id": 831, "query": "NF2 (Merlin) prevents phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila."}
{"query_id": 1012, "query": "Radioiodine treatment of non-toxic multinodular goitre reduces thyroid volume."}
{"query_id": 832, "query": "NFAT4 activation requires IP3R-mediated Ca2+ mobilization."}
{"query_id": 834, "query": "NOX2-independent pathways can generate peroxynitrite by reacting with nitrogen intermediates."}
{"query_id": 956, "query": "Pleiotropic coupling of GLP-1R to intracellular effectors promotes distinct profiles of cellular signaling."}
{"query_id": 50, "query": "AIRE is expressed in some skin tumors."}
{"query_id": 715, "query": "Low expression of miR7a does represses target genes and exerts a biological function in ovaries."}
{"query_id": 957, "query": "Podocytes are motile and migrate in the presence of injury."}
{"query_id": 51, "query": "ALDH1 expression is associated with better breast cancer outcomes."}
{"query_id": 716, "query": "Low expression of miR7a exerts a biological function in testis."}
{"query_id": 837, "query": "NR5A2 is important in development of endometrial tissues."}
{"query_id": 53, "query": "ALDH1 expression is associated with poorer prognosis in breast cancer."}
{"query_id": 718, "query": "Low nucleosome occupancy correlates with low methylation levels across species."}
{"query_id": 839, "query": "Nanoparticles can be targeted against specific cell types by incorporating aptamers into lipid nanoparticles."}
{"query_id": 54, "query": "AMP-activated protein kinase (AMPK) activation increases inflammation-related fibrosis in the lungs."}
{"query_id": 56, "query": "APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation causing GABA neuron degeneration."}
{"query_id": 57, "query": "APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation, delaying GABA neuron degeneration."}
{"query_id": 1274, "query": "The tip of the inner tube of the toxic type VI secretion system (T6SS) antibacterial effector in Escherichia coli (E. coli) carries toxic effector proteins."}
{"query_id": 1395, "query": "p16INK4A accumulation is  linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs)."}
{"query_id": 1273, "query": "The sliding activity of kinesin-8 protein Kip3 promotes bipolar spindle assembly."}
{"query_id": 1272, "query": "The single flash-evoked ERG b-wave is generated by activity of ON-bipolar cells."}
{"query_id": 1150, "query": "Tetraspanin-3 is a causative factor in the development of acute myelogenous leukemia"}
{"query_id": 1271, "query": "The severity of cardiac involvement in amyloidosis can be described by the degree of transmurality of late gadolinium enhancement in MRI."}
{"query_id": 1270, "query": "The risk of male prisoners harming themselves is ten times that of female prisoners."}
{"query_id": 163, "query": "Bariatric surgery has a positive impact on mental health."}
{"query_id": 1029, "query": "Reduced responsiveness to interleukin-2 in regulatory T cells is associated with greater resistance to autoimmune diseases such as Type 1 Diabetes."}
{"query_id": 960, "query": "Polymeal nutrition reduces cardiovascular mortality."}
{"query_id": 1389, "query": "mTORC2 regulates intracellular cysteine levels through xCT inhibition."}
{"query_id": 1146, "query": "Teaching hospitals do not provide better care than non-teaching hospitals."}
{"query_id": 1024, "query": "Recurrent mutations occur frequently within CTCF anchor sites adjacent to oncogenes."}
{"query_id": 1266, "query": "The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer."}
{"query_id": 721, "query": "Lupus-prone mice infected with curliproducing bacteria have higher autoantibody titers compared to controls."}
{"query_id": 1144, "query": "Taxation of sugar-sweetened beverages had no effect on the incidence rate of type II diabetes in India."}
{"query_id": 723, "query": "Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions."}
{"query_id": 845, "query": "Neutrophil extracellular traps (NETs) are released by ANCA-stimulated neutrophils."}
{"query_id": 967, "query": "Pretreatment with the Arp2/3 inhibitor CK-666 affects lamelliopodia formation."}
{"query_id": 847, "query": "New drugs for tuberculosis often do not penetrate the necrotic portion of a tuberculosis lesion in high concentrations."}
{"query_id": 727, "query": "Ly6C hi monocytes have a lower inflammatory capacity compared to their Ly6C lo counterparts."}
{"query_id": 728, "query": "Ly6C hi monocytes have a lower inflammatory capacity than Ly6C lo monocytes."}
{"query_id": 729, "query": "Lymphadenopathy is observed in knockin mouse lacking the SHP-2 MAPK pathway."}
{"query_id": 1163, "query": "The DdrB protein from Deinococcus radiodurans is an alternative SSB."}
{"query_id": 1041, "query": "Replacement of histone H2A with H2A.Z slows gene activation in yeasts by stabilizing +1 nucleosomes."}
{"query_id": 171, "query": "Basophils counteract disease development in patients with systemic lupus erythematosus (SLE)."}
{"query_id": 1282, "query": "Therapeutic use of the drug Dapsone to treat pyoderma gangrenous is based on anecdotal evidence."}
{"query_id": 1281, "query": "The ureABIEFGH gene cluster is induced by nickel (II) ion."}
{"query_id": 294, "query": "Crossover hot spots are not found within gene promoters in Saccharomyces cerevisiae."}
{"query_id": 1280, "query": "The ureABIEFGH gene cluster encodes urease maturation proteins : UreD/UreH, UreE, UreF, and UreG."}
{"query_id": 295, "query": "Crosstalk between dendritic cells (DCs) and innate lymphoid cells (ILCs) is important in the regulation of intestinal homeostasis."}
{"query_id": 298, "query": "Cytochrome c is released from the mitochondrial intermembrane space to cytosol during apoptosis."}
{"query_id": 179, "query": "Birth-weight is positively associated with breast cancer."}
{"query_id": 971, "query": "Primary cervical cancer screening with HPV detection has higher longitudinal sensitivity than conventional cytology to detect cervical intraepithelial neoplasia grade 2."}
{"query_id": 1279, "query": "The treatment of cancer patients with co-IR blockade precipitates adverse autoimmune events."}
{"query_id": 1278, "query": "The treatment of cancer patients with co-IR blockade does not cause any adverse autoimmune events."}
{"query_id": 852, "query": "Non-invasive ventilation use should be decreased if there is inadequate response to conventional treatment."}
{"query_id": 975, "query": "Primary pro-inflammatory cytokines induce secondary pro- and anti-inflammatory mediators."}
{"query_id": 613, "query": "Increased microtubule acetylation repairs LRRK2 Roc-COR domain mutation induced locomotor deficits."}
{"query_id": 70, "query": "Activation of PPM1D suppresses p53 function."}
{"query_id": 72, "query": "Activator-inhibitor pairs are provided dorsally by Admpchordin."}
{"query_id": 859, "query": "Normal expression of RUNX1 has tumor-promoting effects."}
{"query_id": 619, "query": "Increased vessel density along with a reduction in fibrosis decreases the efficacy of chemotherapy treatments."}
{"query_id": 75, "query": "Active H. pylori urease has a polymeric structure that compromises two subunits, UreA and UreB."}
{"query_id": 1175, "query": "The PPR MDA5 has two N-terminal CARD domains."}
{"query_id": 180, "query": "Blocking the interaction between TDP-43 and respiratory complex I proteins ND3 and ND6 leads to increased TDP-43-induced neuronal loss."}
{"query_id": 183, "query": "Bone marrow cells contribute to adult macrophage compartments."}
{"query_id": 1292, "query": "There is no association between HNF4A mutations and diabetes risks."}
{"query_id": 185, "query": "Breast cancer development is determined exclusively by genetic factors."}
{"query_id": 1290, "query": "There is an inverse relationship between hip fractures and statin use."}
{"query_id": 1049, "query": "Ribosomopathies have a low degree of cell and tissue specific pathology."}
{"query_id": 982, "query": "Proteins synthesized at the growth cone are ubiquitinated at a higher rate than proteins from the cell body."}
{"query_id": 742, "query": "Macrolides have no protective effect against myocardial infarction."}
{"query_id": 501, "query": "Headaches are not correlated with cognitive impairment."}
{"query_id": 743, "query": "Macrolides protect against myocardial infarction."}
{"query_id": 985, "query": "Pseudogene PTENP1 regulates the expression of PTEN by functioning as an miRNA decoy."}
{"query_id": 502, "query": "Healthcare delivery efficiency in crowded delivery centers is impaired by improving structural, logistical, and interpersonal elements."}
{"query_id": 623, "query": "Individuals with low serum vitamin D concentrations have increased risk of multiple sclerosis."}
{"query_id": 744, "query": "Macropinocytosis contributes to a cell's supply of amino acids via the intracellular uptake of protein."}
{"query_id": 507, "query": "Helminths interfere with immune system control of macrophages activated by IL-4 favor Mycobacterium tuberculosis replication."}
{"query_id": 628, "query": "Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of African origin."}
{"query_id": 508, "query": "Hematopoietic Stem Cell purification reaches purity rate of up to 50%."}
{"query_id": 1187, "query": "The YAP1 and TEAD complex tanslocates into the nucleus where it interacts with transcription factors and DNA-binding proteins that modulate target gene transcription."}
{"query_id": 1185, "query": "The US health care system can save up to $750 million if 7% of patients waiting for kidney transplants participate in the optimized national kidney paired donation program."}
{"query_id": 1062, "query": "S-nitrosylated GAPDH physiologically transnitrosylates histone deacetylases."}
{"query_id": 1180, "query": "The PRR MDA5 is a sensor of RNA virus infection."}
{"query_id": 198, "query": "CCL19 is absent within dLNs."}
{"query_id": 870, "query": "Obesity decreases life quality."}
{"query_id": 993, "query": "Pyridostatin destabilizes the G - quadruplex in the telomeric region."}
{"query_id": 873, "query": "Obesity is determined solely by environmental factors."}
{"query_id": 1179, "query": "The PRR MDA5 has a central DExD/H RNA helices domain."}
{"query_id": 1298, "query": "Thigh-length graduated compression stockings (GCS) did not reduce deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke."}
{"query_id": 513, "query": "High cardiopulmonary fitness causes increased mortality rate."}
{"query_id": 514, "query": "High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter."}
{"query_id": 756, "query": "Many proteins in human cells can be post-translationally modified at lysine residues via acetylation."}
{"query_id": 636, "query": "Inositol lipid 3-phosphatase PTEN converts Ptdlns(3,4)P 2 into phosphatidylinositol 4-phosphate."}
{"query_id": 516, "query": "High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD)."}
{"query_id": 637, "query": "Input from  mental and physical health care professionals is effective at decreasing homelessness."}
{"query_id": 879, "query": "Occupancy of ribosomes by IncRNAs do not make functional peptides."}
{"query_id": 517, "query": "High levels of copeptin decrease risk of diabetes."}
{"query_id": 759, "query": "Mathematical models predict that using Artemisinin-based combination therapy over nongametocytocidal drugs have a dramatic impact in reducing malaria transmission."}
{"query_id": 94, "query": "Albendazole is used to treat lymphatic filariasis."}
{"query_id": 99, "query": "Alizarin forms hydrogen bonds with residues involved in PGAM1 substrate binding."}
{"query_id": 1197, "query": "The availability of safe places to study is not effective at decreasing homelessness."}
{"query_id": 1196, "query": "The availability of safe places to study is effective at decreasing homelessness."}
{"query_id": 1194, "query": "The arm density of TatAd complexes is due to structural rearrangements within Class1 TatAd complexes such as the 'charge zipper mechanism'."}
{"query_id": 1191, "query": "The amount of publicly available DNA data doubles every 10 years."}
{"query_id": 880, "query": "Occupancy of ribosomes by IncRNAs mirror 5 0-UTRs"}
{"query_id": 882, "query": "Omnivores produce less trimethylamine N-oxide from dietary I-carnitine than vegetarians."}
{"query_id": 641, "query": "Insomnia can be effectively treated with cognitive behavioral therapy."}
{"query_id": 521, "query": "High-sensitivity cardiac troponin T (HSCT-T) dosage may not be diagnostic if the onset of symptoms occurs less than 3 hours before acute myocardial injury (AMI)."}
{"query_id": 644, "query": "Insulin increases risk of severe kidney failure."}
{"query_id": 887, "query": "Only a minority of cells survive development after differentiation into stress-resistant spores."}
{"query_id": 525, "query": "Histone demethylase recruitment and a transient decrease in histone methylation is necessary for ligand-dependent induction of transcription by nuclear receptors."}
{"query_id": 768, "query": "Mercaptopurine is anabolized into the inactive methylmercaptopurine by thiopurine methyltrasnferase (TPMT)."}
{"query_id": 527, "query": "Homozygous deletion of murine Sbds gene from osterix-expressing mesenchymal stem and progenitor cells (MPCs) prevents oxidative stress."}
{"query_id": 528, "query": "Human T-lymphotropic virus type-I-associated myelopathy / tropical spastic paraparesis (HAM/TSP) patients produce Immunoglobulin G (IgG) antibodies which cross-react with an immunodominant epitope in Tax."}
{"query_id": 649, "query": "Integrating classroom-based collaborative learning with Web-based collaborative learning leads to subpar class performance"}
{"query_id": 1088, "query": "Silencing of Bcl2 is important for the maintenance and progression of tumors."}
{"query_id": 1086, "query": "Sildenafil improves erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants."}
{"query_id": 770, "query": "Metastatic colorectal cancer treated with a single agent fluoropyrimidines resulted in reduced efficacy and lower quality of life when compared with oxaliplatin-based chemotherapy in elderly patients."}
{"query_id": 410, "query": "Febrile seizures increase the threshold for development of epilepsy."}
{"query_id": 411, "query": "Febrile seizures reduce the threshold for development of epilepsy."}
{"query_id": 532, "query": "Hyperfibrinogenemia decreases rates of femoropopliteal bypass thrombosis."}
{"query_id": 533, "query": "Hyperfibrinogenemia increases rates of femoropopliteal bypass thrombosis."}
{"query_id": 775, "query": "Mice defective for deoxyribonucleic acid (DNA) polymerase I (polI) reveal increased sensitivity to ionizing radiation (IR)."}
{"query_id": 1199, "query": "The benefits of colchicine were achieved with effective widespread use of secondary prevention strategies such as high-dose statins."}
{"query_id": 535, "query": "Hypertension is frequently observed in type 1 diabetes patients."}
{"query_id": 415, "query": "Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for dementia."}
{"query_id": 536, "query": "Hypocretin neurones induce panicprone state in rats."}
{"query_id": 659, "query": "Ivermectin is used to treat lymphatic filariasis."}
{"query_id": 539, "query": "Hypoglycemia increases the risk of dementia."}
{"query_id": 1099, "query": "Statins decrease blood cholesterol."}
{"query_id": 660, "query": "Ivermectin is used to treat onchocerciasis."}
{"query_id": 781, "query": "Mice that lack Interferon-\u03b3 or its receptor exhibit high resistance to experimental autoimmune myocarditis."}
{"query_id": 540, "query": "Hypothalamic glutamate neurotransmission is crucial to energy balance."}
{"query_id": 783, "query": "Mice without IFN-\u03b3 or its receptor are resistant to EAM induced with \u03b1-MyHC/CFA."}
{"query_id": 300, "query": "Cytosolic proteins bind to iron-responsive elements on mRNAs coding for DMT1. Cytosolic proteins bind to iron-responsive elements on mRNAs coding for proteins involved in iron uptake."}
{"query_id": 421, "query": "Flexible molecules experience greater steric hindrance in the tumor microenviroment than rigid molecules."}
{"query_id": 784, "query": "MicroRNA is involved in the regulation of Neural Stem Cell (NSC) differentiation and proliferation dynamic homeostasis"}
{"query_id": 785, "query": "Microarray results from culture-amplified mixtures of serotypes correlate poorly with microarray results from uncultured mixtures."}
{"query_id": 544, "query": "IFIT1 restricts viral replication by sequestrating mis-capped viral RNAs."}
{"query_id": 303, "query": "DMRT1 is a sex-determining gene that is epigenetically regulated by the MHM region."}
{"query_id": 1089, "query": "Smc5/6 engagment drives the activation of SUMO E3 ligase Mms21 by ATP-dependent remolding."}
{"query_id": 549, "query": "IRG1 has antiviral effects against neurotropic viruses."}
{"query_id": 551, "query": "ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR)."}
{"query_id": 793, "query": "Mitochondria are uninvolved in apoptosis."}
{"query_id": 431, "query": "FoxO3a activation in neuronal death is mediated by reactive oxygen species (ROS)."}
{"query_id": 552, "query": "IgA plasma cells that are specific for transglutaminase 2 accumulate in the duodenal mucosa on commencement of a gluten-free diet."}
{"query_id": 674, "query": "LDL cholesterol has no involvement in the development of cardiovascular disease."}
{"query_id": 312, "query": "De novo assembly of sequence data has more specific contigs than unassembled sequence data."}
{"query_id": 554, "query": "Immune complex triggered cell death leads to extracellular release of neutrophil protein HMGB1."}
{"query_id": 314, "query": "Deamination of cytidine to uridine on the minus strand of viral DNA results in catastrophic G-to-A mutations in the viral genome."}
{"query_id": 436, "query": "Free histones are degraded by a Rad53-dependent mechanism once DNA has been replicated."}
{"query_id": 437, "query": "Functional consequences of genomic alterations due to Myelodysplastic syndrome (MDS) are poorly understood due to the lack of an animal model."}
{"query_id": 439, "query": "Fz/PCP-dependent Pk localizes to the anterior membrane of neuroectoderm cells during zebrafish neuralation"}
{"query_id": 560, "query": "Immune responses result in the development of inflammatory Th17 cells and anti-inflammatory iTregs."}
{"query_id": 440, "query": "Fz/PCP-dependent Pk localizes to the anterior membrane of notochord cells during zebrafish neuralation."}
{"query_id": 1303, "query": "Tirasemtiv has no effect on fast-twitch muscle."}
{"query_id": 684, "query": "Lack of clpC does not affect sporulation efficiency in Bacillus subtilis cells."}
{"query_id": 443, "query": "GATA-3 is important for hematopoietic stem cell (HSC) function."}
{"query_id": 324, "query": "Deleting Raptor reduces G-CSF levels."}
{"query_id": 327, "query": "Deletion of \u03b1v\u03b28 does not result in a spontaneous inflammatory phenotype."}
{"query_id": 569, "query": "In adult tissue, most T cells are memory T cells."}
{"query_id": 208, "query": "CHEK2 is not associated with breast cancer."}
{"query_id": 690, "query": "Less than 10% of the gabonese children with Schimmelpenning-Feuerstein-Mims syndrome (SFM) had a plasma lactate of more than 5mmol/L."}
{"query_id": 691, "query": "Leukemia associated Rho guanine nucleotide-exchange factor represses RhoA in response to SRC activation."}
{"query_id": 692, "query": "Leuko-increased blood increases infectious complications in red blood cell transfusion."}
{"query_id": 1316, "query": "Transferred UCB T cells acquire a memory-like phenotype in recipients."}
{"query_id": 693, "query": "Leuko-reduced blood reduces infectious complications in red blood cell transfusion."}
{"query_id": 452, "query": "Gene expression does not vary appreciably across genetically identical cells."}
{"query_id": 212, "query": "CR is associated with higher methylation age."}
{"query_id": 575, "query": "In domesticated populations of Saccharomyces cerevisiae, whole chromosome aneuploidy is very uncommon."}
{"query_id": 213, "query": "CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery."}
{"query_id": 577, "query": "In mice, P. chabaudi parasites are able to proliferate faster early in infection when inoculated at lower numbers than when inoculated at high numbers."}
{"query_id": 578, "query": "In mouse models, the loss of CSF1R facilitates MOZ-TIF2-induced leuekmogenesis."}
{"query_id": 216, "query": "CX3CR1 on the Th2 cells impairs T cell survival"}
{"query_id": 217, "query": "CX3CR1 on the Th2 cells promotes T cell survival"}
{"query_id": 338, "query": "Dexamethasone decreases risk of postoperative bleeding."}
{"query_id": 218, "query": "CX3CR1 on the Th2 cells promotes airway inflammation."}
{"query_id": 219, "query": "CX3CR1 on the Th2 cells suppresses airway inflammation."}
{"query_id": 1319, "query": "Transplanted human glial cells can differentiate within the host animal."}
{"query_id": 100, "query": "All hematopoietic stem cells segregate their chromosomes randomly."}
{"query_id": 1204, "query": "The combination of H3K4me3 and H3K79me2 is found in quiescent hair follicle stem cells."}
{"query_id": 343, "query": "Diabetic patients with acute coronary syndrome experience increased short-term and long-term risk for bleeding events."}
{"query_id": 1202, "query": "The center of the granuloma in an immune cell induces a pro-inflammatory immune response."}
{"query_id": 587, "query": "In transgenic mice harboring green florescent protein under the control of the Sox2 promoter, less than ten percent of the cells with green florescent colocalize with cell proliferation markers."}
{"query_id": 1200, "query": "The binding orientation of the ML-SA1 activator at hTRPML2 is different from the binding orientation of the ML-SA1 activator at hTRPML1."}
{"query_id": 589, "query": "In young and middle-aged adults, current or remote uses of ADHD medications do not increase the risk of serious cardiovascular events."}
{"query_id": 1320, "query": "Transplanted human glial progenitor cells are incapable of forming a neural network with host animals' neurons."}
{"query_id": 903, "query": "PD-1 triggering on monocytes reduces IL-10 production by monocytes."}
{"query_id": 904, "query": "PDPN promotes efficient motility along stromal surfaces by activating the C-type lectin receptor to rearrange the actin cytoskeleton in dendritic cells."}
{"query_id": 1207, "query": "The composition of myosin-II isoform switches from the polarizable B isoform to the more homogenous A isoform during hematopoietic differentiation."}