Key international posts held by Dr. Sprenger include being the ECDC Management Board ’s founding Chairman (2004 – 2008), and being a member of the Executive Board of the International Association of Public Health Institutes (IANPHI) (2008-2010).
Dr. Sprenger je zasedal tudi nekaj mednarodnih položajev, med drugim je bil ustanovni predsednik upravnega odbora ECDC (2004– 2008) in član izvršnega odbora Mednarodne organizacije nacionalnih inštitutov za javno zdravje (IANPHI) (2008– 2010).