{"primaryAccession": "A0A0A7EQR3", "text": "This is 4-O-methyl-glucuronoyl methylesterase protein, from Canker rot fungus, contains 474 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A0A0A7EQR3", "organism_name": "Canker rot fungus", "protein_name": "4-O-methyl-glucuronoyl methylesterase", "length": 474, "firstPublicDate": "2016-04-13", "FUNCTION": "Glucuronoyl esterase which may play a significant role in biomass degradation, as it is considered to disconnect hemicellulose from lignin through the hydrolysis of the ester bond between 4-O-methyl-D-glucuronic acid residues of glucuronoxylans and aromatic alcohols of lignin (PubMed:25425346, PubMed:26712478)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the carbohydrate esterase 15 (CE15) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFKPSFVALALVSYATAQASAPQWGQCGGIGWTGPTACPSGWACQQLNAYYSQCLQGAAPAPARTTAAPPPPPATTAAPPPPTTSAPTGSSPVAGACGAIASTVPNYNNAKLPDPFTFANGTALRTKADWSCRRAEISALIQNYEAGTLPPKPPVVTASFSKSGNTGTLAITAGLSNSQTIKFSPTISYPSGTPPANGWPLIIAYEGGSIPIPAGVATLTYSNSDMAQQNSASSRGQGLFYQLYGSTHSASAMTAWVWGVSRIIDALEMTPTAQINTQRIGVTGCSRDGKGALMAGAFEERIALTIPQESGSGGDACWRLSKYEIDNGNQVQDAVEIVGENVWFSTNFNNYVQKLPTVPEDHHLLAAMVAPRAMISFENTDYLWLSPMSSFGCMTAAHTVWQGLGIADSHGFAQVGGHAHCAWPSSLTPQLNAFINRFLLDQSATTNVFTTNNQFGKVQWNAANWITWTTPTLT", "length": 474, "molWeight": 49910, "crc64": "7E1F16E59E5E3413", "md5": "6A26B5B5E42C8553ACEC952CBC071AC9"}}
{"primaryAccession": "A0AVI4", "text": "This is E3 ubiquitin-protein ligase TM129 protein, from Human, contains 362 amino acids, has 1 RING-type; degenerate Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [285, 350], "description": "RING-type; degenerate", "keyword_description": "Zinc finger", "textural_description": "RING-type; degenerate Zinc finger"}], "meta_data": {"primaryAccession": "A0AVI4", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase TM129", "length": 362, "firstPublicDate": "2007-06-12", "FUNCTION": "E3 ubiquitin-protein ligase involved in ER-associated protein degradation, preferentially associates with the E2 enzyme UBE2J2, Exploited by viral US11 proteins to mediate HLA class I proteins degradation", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the TMEM129 family", "domain_description": {"RING-type; degenerate Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDSPEVTFTLAYLVFAVCFVFTPNEFHAAGLTVQNLLSGWLGSEDAAFVPFHLRRTAATLLCHSLLPLGYYVGMCLAASEKRLHALSQAPEAWRLFLLLAVTLPSIACILIYYWSRDRWACHPLARTLALYALPQSGWQAVASSVNTEFRRIDKFATGAPGARVIVTDTWVMKVTTYRVHVAQQQDVHLTVTESRQHELSPDSNLPVQLLTIRVASTNPAVQAFDIWLNSTEYGELCEKLRAPIRRAAHVVIHQSLGDLFLETFASLVEVNPAYSVPSSQELEACIGCMQTRASVKLVKTCQEAATGECQQCYCRPMWCLTCMGKWFASRQDPLRPDTWLASRVPCPTCRARFCILDVCTVR", "length": 362, "molWeight": 40464, "crc64": "861C9876B492DC56", "md5": "557E0E26953E08AC915E39ED8432218A"}}
{"primaryAccession": "A0AVK6", "text": "This is Transcription factor E2F8 protein, from Human, contains 867 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A0AVK6", "organism_name": "Human", "protein_name": "Transcription factor E2F8", "length": 867, "firstPublicDate": "2007-08-21", "FUNCTION": "Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells, Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3', Directly represses transcription of classical E2F transcription factors such as E2F1: component of a feedback loop in S phase by repressing the expression of E2F1, thereby preventing p53/TP53-dependent apoptosis, Plays a key role in polyploidization of cells in placenta and liver by regulating the endocycle, probably by repressing genes promoting cytokinesis and antagonizing action of classical E2F proteins (E2F1, E2F2 and/or E2F3), Required for placental development by promoting polyploidization of trophoblast giant cells, Acts as a promoter of sprouting angiogenesis, possibly by acting as a transcription activator: associates with HIF1A, recognizes and binds the VEGFA promoter, which is different from canonical E2 recognition site, and activates expression of the VEGFA gene", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the E2F/DP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPTANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGHPDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEVSTEDVH", "length": 867, "molWeight": 94166, "crc64": "AADBCFACB888BD93", "md5": "12CF6FF8B4D4C1D9AF26AA5FD8A195F3"}}
{"primaryAccession": "A0PJY2", "text": "This is Fez family zinc finger protein 1 protein, from Human, contains 475 amino acids, has 6 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [260, 282], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [288, 310], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [316, 338], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [344, 366], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [372, 394], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [400, 423], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "A0PJY2", "organism_name": "Human", "protein_name": "Fez family zinc finger protein 1", "length": 475, "firstPublicDate": "2007-07-10", "FUNCTION": "Transcription repressor, Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN), Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation, Expression is required in OSN to cell-autonomously regulate OSN axon projections, Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons, May be required for correct rostral migration of the interneuron progenitors (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 6}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDSSCHNATTKMLATAPARGNMMSTSKPLAFSIERIMARTPEPKALPVPHFLQGALPKGEPKHSLHLNSSIPCMIPFVPVAYDTSPKAGVTGSEPRKASLEAPAAPAAVPSAPAFSCSDLLNCALSLKGDLARDALPLQQYKLVRPRVVNHSSFHAMGALCYLNRGDGPCHPAAGVNIHPVASYFLSSPLHPQPKTYLAERNKLVVPAVEKYPSGVAFKDLSQAQLQHYMKESAQLLSEKIAFKTSDFSRGSPNAKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSSLGLARTPAGEPGTEPPPPLPQQPPMTLPPLQPPLPTPGPLQPGLHQGHQ", "length": 475, "molWeight": 52038, "crc64": "A26945A0C4E9316A", "md5": "96557DA96D7518F87C7FC4193791BAB3"}}
{"primaryAccession": "A1XGB4", "text": "This is CASP-like protein PIMP1 protein, from Capsicum pepper, contains 166 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A1XGB4", "organism_name": "Capsicum pepper", "protein_name": "CASP-like protein PIMP1", "length": 166, "firstPublicDate": "2010-02-09", "FUNCTION": "Required for defense response to Xanthomonas campestris pv, vesicatoria (Xcv), In heterologous systems, confers resistance to bacterial pathogens such as Pseudomonas syringae pv, tomato but susceptibility to pathogenic oomycetes such as Hylaloperonospora parasitica when expressed in Arabidopsis thaliana, May be involved in the regulation of responses to bitoic and abiotic stresses", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Casparian strip membrane proteins (CASP) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTPPPTSTVPPYVSLIVRILTLICLLISFIVIATNNQTVSTVAGDVKIKFKDFYAYRYLIATVIIGMAYTLLQIAFSISLLTTGNRIGGEGFLLFDFYGDKFISYFLVTGAAASFGMTQDLKQLEGSDNYSKFLNTSNAAASLCLIGFFFAVASSIFSSYNLPKRI", "length": 166, "molWeight": 18155, "crc64": "F0003F11D9913713", "md5": "838C1C60A31FFE8FA0733959A452B725"}}
{"primaryAccession": "A2AMM0", "text": "This is Caveolae-associated protein 4 protein, from Mouse, contains 362 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A2AMM0", "organism_name": "Mouse", "protein_name": "Caveolae-associated protein 4", "length": 362, "firstPublicDate": "2008-03-18", "FUNCTION": "Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation, Facilitates the recruitment of MAPK1/3 to caveolae within cardiomyocytes and regulates alpha-1 adrenergic receptor-induced hypertrophic responses in cardiomyocytes through MAPK1/3 activation (PubMed:24567387), Contributes to proper membrane localization and stabilization of caveolin-3 (CAV3) in cardiomyocytes (PubMed:26497963), Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway (PubMed:18332105)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CAVIN family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEHNGSASNAGKIHQNRLSSVTEDEDQDAALTIVTVLDRVASVVDSVQASQKRIEERHREMGNAIKSVQIDLLKLSQSHSNTGYVVNKLFEKTRKVSAHIKDVKARVEKQQVRVTKVETKQEEIMKKNKFRVVIFQEDIPCPASLSVVKDRSLPENQEEAEEVFDPPIELSSDEEYYVEESRSARLRKSGKEHIDHIKKAFSRENMQKTRQTLDKKVSGIRTRIVTPERRERLRQSGERLRQSGERLRQSGERFKKSISSAAPSKEAFKIRSLRKAKDPKAEGQEVDRGMGVDIISGSLALGPIHEFHSDEFSETEKEVTKGGYSPQEGGDPPTPEPLKVTFKPQVRVEDDESLLLELKQSS", "length": 362, "molWeight": 41008, "crc64": "3A3DDAEA43DCF209", "md5": "01369004C4BDB631A0D7CA619D11D66F"}}
{"primaryAccession": "A2APC3", "text": "This is Probable tubulin polyglutamylase TTLL9 protein, from Mouse, contains 461 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A2APC3", "organism_name": "Mouse", "protein_name": "Probable tubulin polyglutamylase TTLL9", "length": 461, "firstPublicDate": "2008-03-18", "FUNCTION": "Probable tubulin polyglutamylase that generates side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of target proteins (PubMed:27257088), Similar to TTLL1, may acquire enzymatic activity only in complex with other proteins as it is most likely lacking domains important for autonomous activity (Probable), Mediates tubulin polyglutamylation which induces establishment of microtubule heterogeneity in sperm flagella, thereby playing a role in normal motile flagella axoneme structure and sperm flagella beating pattern (PubMed:27257088)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the tubulin--tyrosine ligase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSRQKNQNSKGHGVSKGKEREQRTLIRFKTTLMNTLMDVLRHRPGWVEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKYLERESGKTEAAKCDFFPKTFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIMDWRKGTSGKKPTGVETQPARANMNPSGSHDTRSSDDQKDDLPVENYVAQRYVENPYLIGGRKFDLRVYVLVMSYIPLRAWLYRDGFARFSNTRFTLNSIDDHYVHLTNVAVQKTSPDYHLKKGCKWMLQRFRQYLASKHGPKAVETLFSDMDNIFIKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGKEKRVGGFDLMWNDGPVSREDGPSDLSGMGNFVTNTHLGCVNDRKEQLRQLFRSLQAQRKAPS", "length": 461, "molWeight": 54107, "crc64": "6E83E3C9A4788EAD", "md5": "F5D89C2FF5D299F9AE43D363EF3752DC"}}
{"primaryAccession": "A2AR95", "text": "This is Low-density lipoprotein receptor class A domain-containing protein 3 protein, from Mouse, contains 345 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A2AR95", "organism_name": "Mouse", "protein_name": "Low-density lipoprotein receptor class A domain-containing protein 3", "length": 345, "firstPublicDate": "2007-09-11", "FUNCTION": "May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production (PubMed:21795536), May regulate ITCH and NEDD4 E3 ligase activity and degradation (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the LDLR family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MWLLGPLCLLLSSTAESQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGIHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCRNGLCIDKSFICDGQNNCQDNSDEESCESSLEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHHCNVTYNVNNGVQYVATQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSAYSASSQAASSLLSVEASSHNPEQPGSPEGSAEPRDSVPSQGTEEV", "length": 345, "molWeight": 37467, "crc64": "E3EEE9F188DC5209", "md5": "872E51EDF5D6761CE3845DAA167931E3"}}
{"primaryAccession": "A2XFC1", "text": "This is DNA topoisomerase 6 subunit A3 protein, from Rice, contains 442 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A2XFC1", "organism_name": "Rice", "protein_name": "DNA topoisomerase 6 subunit A3", "length": 442, "firstPublicDate": "2013-04-03", "FUNCTION": "Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles, Relaxes both positive and negative superturns and exhibits a strong decatenase activity (By similarity), May be involved in cell proliferation and stress tolerance", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TOP6A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSEKKRRGGAGAGAASGSASKKPRVSTAASYAESLRSKLRPDASILATLRSLASACSKSKPAGSSSSSSSASKALAAEDDPAASYIVVADQDSASVTSRINRLVLAAARSILSGRGFSFAVPSRAASNQVYLPDLDRIVLVRRESARPFANVATARKATITARVLSLVHAVLRRGIHVTKRDLFYTDVKLFGDQAQSDAVLDDVSCMLGCTRSSLHVVASEKGVVVGRLTFADDGDRIDCTRMGVGGKAIPPNIDRVSGIESDALFILLVEKDAAFMRLAEDRFYNRFPCIILTAKGQPDVATRLFLRRLKVELKLPVLALVDSDPYGLKILSVYMCGSKNMSYDSANLTTPDIKWLGVRPSDLDKYRVPEQCRLPMTDHDIKVGKELLEEDFVKQNEGWVKELETMLRTRQKAEIQALSSFGFQYLTEVYLPLKLQQQDWI", "length": 442, "molWeight": 48242, "crc64": "1397867773A726BB", "md5": "9BE87B40E0353C52A66A726E0DFF168C"}}
{"primaryAccession": "A4D1B5", "text": "This is Gamma-secretase-activating protein protein, from Human, contains 854 amino acids, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A4D1B5", "organism_name": "Human", "protein_name": "Gamma-secretase-activating protein", "length": 854, "firstPublicDate": "2008-05-20", "FUNCTION": "Regulator of gamma-secretase activity, which specifically activates the production of amyloid-beta protein (amyloid-beta protein 40 and amyloid-beta protein 42), without affecting the cleavage of other gamma-secretase targets such has Notch, The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein), Specifically promotes the gamma-cleavage of APP CTF-alpha (also named APP-CTF) by the gamma-secretase complex to generate amyloid-beta, while it reduces the epsilon-cleavage of APP CTF-alpha, leading to a low production of AICD", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GSAP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALRLVADFDLGKDVLPWLRAQRAVSEASGAGSGGADVLENDYESLHVLNVERNGNIIYTYKDDKGNVVFGLYDCQTRQNELLYTFEKDLQVFSCSVNSERTLLAASLVQSTKEGKRNELQPGSKCLTLLVEIHPVNNVKVLKAVDSYIWVQFLYPHIESHPLPENHLLLISEEKYIEQFRIHVAQEDGNRVVIKNSGHLPRDRIAEDFVWAQWDMSEQRLYYIDLKKSRSILKCIQFYADESYNLMFEVPLDISLSNSGFKLVNFGCDYHQYRDKFSKHLTLCVFTNHTGSLCVCYSPKCASWGQITYSVFYIHKGHSKTFTTSLENVGSHMTKGITFLNLDYYVAVYLPGHFFHLLNVQHPDLICHNLFLTGNNEMIDMLPHCPLQSLSGSLVLDCCSGKLYRALLSQSSLLQLLQNTCLDCEKMAALHCALYCGQGAQFLEAQIIQWISENVSACHSFDLIQEFIIASSYWSVYSETSNMDKLLPHSSVLTWNTEIPGITLVTEDIALPLMKVLSFKGYWEKLNSNLEYVKYAKPHFHYNNSVVRREWHNLISEEKTGKRRSAAYVRNILDNAVKVISNLEARNLGPRLTPLLQEEDSHQRLLMGLMVSELKDHFLRHLQGVEKKKIEQMVLDYISKLLDLICHIVETNWRKHNLHSWVLHFNSRGSAAEFAVFHIMTRILEATNSLFLPLPPGFHTLHTILGVQCLPLHNLLHCIDSGVLLLTETAVIRLMKDLDNTEKNEKLKFSIIVRLPPLIGQKICRLWDHPMSSNIISRNHVTRLLQNYKKQPRNSMINKSSFSVEFLPLNYFIEILTDIESSNQALYPFEGHDNVDAEFVEEAALKHTAMLLGL", "length": 854, "molWeight": 97802, "crc64": "D7B4A3A95E2E8C3B", "md5": "D71FF187867BD6060EF7D63B157928B3"}}
{"primaryAccession": "A4Q9F4", "text": "This is Tubulin polyglutamylase TTLL11 protein, from Mouse, contains 727 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A4Q9F4", "organism_name": "Mouse", "protein_name": "Tubulin polyglutamylase TTLL11", "length": 727, "firstPublicDate": "2008-03-18", "FUNCTION": "Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin (PubMed:17499049, PubMed:20530212), Preferentially mediates ATP-dependent polyglutamate long side-chain elongation over the initiation step of the polyglutamylation reaction (PubMed:17499049, PubMed:20530212), Preferentially modifies the alpha-tubulin tail over a beta-tail (PubMed:17499049), Required for CCSAP localization to both spindle and cilia microtubules (By similarity), Promotes tubulin polyglutamylation which stimulates spastin/SPAST-mediated microtubule severing, thereby regulating microtubule functions (PubMed:20530212)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the tubulin--tyrosine ligase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRRSSPEKKPEAEWEADAAAAAAATAAATESLPAETEKQQGVDAGAAGDPERLELEEQPKDVGRIPTPTRRHAPEEGEARVVRRLPPALPLAQPRPAARALSQLVKARGRSRSRVYRRSAGSMRPVTVDSSKARTSLDALKISLRQLRWKEFPFGRRLPCDIYWHGVSFRDSDILSGQVNKFPGMTEMVRKVTLSRALRIMQNLFPEEYNFYPRSWILPEEFQLFVSQVQTVKEGDPSWKPTFIVKPDSGCQGDGIYLIKDPCDGRLTGTLHNRPAVVQEYIRKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPNPQNLHHVFMHLTNYSLNIHSGKFVHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISLVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPMLLEVNANPSMRIEHEYELSPGVFENIPSLVDEEVKVAVIRDTLRLMDPLKKKKEIHFPDIYMDRKHRIPPVSDRMSSWKHKGSSLSIVRSQQMEKSFTSKEDLNCDPTGGDSEPNPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRNCKLSSSSLSMAAVDILYIDITRRWNSVTVDQRDSGMCLQAFVEAFFFLAQRKFKLQPLHEQVASLIDLCEYHLSVLDEKRLLCHRGRPLQRNPPQMNRPEHSATGSSAPRVIGASKLSQS", "length": 727, "molWeight": 82361, "crc64": "661A7FB585BB9EDB", "md5": "0BEF0C3AEB76AD3D71F2092698936C7A"}}
{"primaryAccession": "A6NNB3", "text": "This is Interferon-induced transmembrane protein 5 protein, from Human, contains 132 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A6NNB3", "organism_name": "Human", "protein_name": "Interferon-induced transmembrane protein 5", "length": 132, "firstPublicDate": "2007-10-02", "FUNCTION": "Required for normal bone mineralization", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the CD225/Dispanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDTAYPREDTRAPTPSKAGAHTALTLGAPHPPPRDHLIWSVFSTLYLNLCCLGFLALAYSIKARDQKVVGDLEAARRFGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLARLAKDSAAFFSTKFDDADYD", "length": 132, "molWeight": 14378, "crc64": "4AB8089B88507024", "md5": "E3E1A1A2F51AB6C966F880C12944F067"}}
{"primaryAccession": "A6YSL1", "text": "This is Ribonuclease III domain-containing protein RNC1, chloroplastic protein, from Maize, contains 525 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A6YSL1", "organism_name": "Maize", "protein_name": "Ribonuclease III domain-containing protein RNC1, chloroplastic", "length": 525, "firstPublicDate": "2016-02-17", "FUNCTION": "Binds specific group II introns in chloroplasts and facilitates their splicing, Acts on both subgroup IIA and subgroup IIB introns, The substrates of the subgroup II also require the CRM domain proteins CAF1 or CAF2, Binds both single-stranded and double-stranded RNA non-specifically, but lacks endonuclease activity, Required for plastid ribosome biogenesis", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGPPAMAFQALTLTPLPFSLHSSSRRVRVLAVAADQTPPPAPPSEPANSPSRLLRELAQRKKAVSPKKKHPPRRFILKPPLDDERLTRRFLSSPQLSLKALPLLSSCLPSAPLSTADRTWMDEYLLEAKQALGYPLAPSETLGEGDDCPARHFDVLFYLAFQHLDPSSERTRMRHVRNGHSRLWFLGQYVLELAFCEFFLQRYPRESPGPMRERVFALIGKKVLPRWLKAASLHNLVFPYDDLDKMIRKDREPPSKAVFWAIFGAIYLCFGMPEVYRVLFEAFGMDPDDESCQPKLRRQLEDVDYVSVEFEKRQLTWQDVAAYRPPPDALFAHPRLFRACVPPGMHRFRGNIWDFDSRPKVMTTLGYPLPMNDRIPEITEARNIELGLGLQLCFLHPSKHKFEHPRFCYERLEYVGQKIQDLVMAERLLMKHLDAPGRWLAEKHRRTLMNKYCGRYLRDKHLQHYIIYGETVQDRFEHNRRLRNPSTTSVQQALHGLAYCVYGKPDVRRLMFEVFDFEQVQPKAV", "length": 525, "molWeight": 61018, "crc64": "E3CA6753D5CD860A", "md5": "B245E512C5418AA17F8F90978678C7ED"}}
{"primaryAccession": "A8MQ27", "text": "This is E3 ubiquitin-protein ligase NEURL1B protein, from Human, contains 555 amino acids, has 1 RING-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [503, 543], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "A8MQ27", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase NEURL1B", "length": 555, "firstPublicDate": "2008-09-02", "FUNCTION": "E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP", "length": 555, "molWeight": 59270, "crc64": "228B459336279423", "md5": "348CC332EAEAD3841D7DD10A1D83F837"}}
{"primaryAccession": "A8MUP2", "text": "This is Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial protein, from Human, contains 240 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A8MUP2", "organism_name": "Human", "protein_name": "Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial", "length": 240, "firstPublicDate": "2008-09-02", "FUNCTION": "Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria (PubMed:28391595, PubMed:28887308), Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methyl group per binding event (PubMed:28887308)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the methyltransferase superfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAALRRMLHLPSLMMGTCRPFAGSLADSCLADRCLWDRLHAQPRLGTVPTFDWFFGYDEVQGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSGSFQLLLDKGTWDAVARGGLPRAYQLLSECLRVLNPQGTLIQFSDEDPDVRLPCLEQGSYGWTVTVQELGPFRGITYFAYLIQGSH", "length": 240, "molWeight": 25910, "crc64": "BCF0FBD4493D2CE6", "md5": "72F2E0A826125DC05AC8C76F439D64EB"}}
{"primaryAccession": "B0BMY1", "text": "This is Lysosomal amino acid transporter 1 homolog protein, from Rat, contains 293 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B0BMY1", "organism_name": "Rat", "protein_name": "Lysosomal amino acid transporter 1 homolog", "length": 293, "firstPublicDate": "2013-10-16", "FUNCTION": "Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the laat-1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVWRTLVASNFSTCPNGSIQWIWDVFGECAQDGWDEASVALGLVSIFCFAASTFPQYIKACKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLLMLTLYFHYKFKKQPSLLSAPINSVLLFILGTVCITPLLSSTDPVAVPREGFRGRTLLSVEPGNKPFTKKEVVGFVIGSASSVLYLLSRLPQIRTNFVRQSTQGISYSLFALVMLGNTLYGLSVLLKNPEVGQSEGSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRSHDADAASEREPLLPS", "length": 293, "molWeight": 32232, "crc64": "357C081C690128E7", "md5": "50AD43DCF1B766A7C15F5F49E792D9C0"}}
{"primaryAccession": "B2D6M2", "text": "This is Protein lin-61 protein, from Caenorhabditis elegans, contains 612 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B2D6M2", "organism_name": "Caenorhabditis elegans", "protein_name": "Protein lin-61", "length": 612, "firstPublicDate": "2012-05-16", "FUNCTION": "Synthetic multivulva class B (synMuvB) protein required to repress the induction of vulval development by Ras signaling, Unlike other synMuv proteins it does not associate with the multiprotein DRM complex and the NuRD-like complex, Interaction with methylated histone H3 is essential for vulva development, It has a role in maintaining genome stability", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLKLVILCFALFYNTVSSTRFLFGVEVKCDFDEVFQLTVSHWEDDGNTFWDRDEDITGRMTMFARKKIFFYQDGHHGFEFGKLEPYGWFLHNCTKNGNFREYRHGLSSTSGSNGLEYIEYTMSEFLKIVRANKKSDRKLDKTYLWESYLHQFEKGKTSFIPVEAFNRNLTVNFNECVKEGVIFETVVHDYDKNCDSIQVRWFARIEKVCGYRVLAQFIGADTKFWLNILSDDMFGLANAAMSDPNMDKIVYAPPLAINEEYQNDMVNYVNNCIDGEIVGQTSLSPKFDEGKALLSKHRFKVGQRLELLNYSNSTEIRVARIQEICGRRMNVSITKKDFPESLPDADDDRQVFSSGSQYWIDEGSFFIFPVGFAAVNGYQLNAKKEYIEHTNKIAQAIKNGENPRYDSDDVTFDQLAKDPIDPMIWRKVKVGQKFELIDPLAQQFNNLHVASILKFCKTEGYLIVGMDGPDALEDSFPIHINNTFMFPVGYAEKYNLELVPPDEFKGTFRWDEYLEKESAETLPLDLFKPMPSQERLDKFKVGLRLEAADMCENQFICPATVKSVHGRLINVNFDGWDEEFDELYDVDSHDILPIGWCEAHSYVLQPPKKYNY", "length": 612, "molWeight": 70910, "crc64": "D0A1B0156C73C254", "md5": "FCA670473FA2747BE70B7048482BC0FC"}}
{"primaryAccession": "B2RYG6", "text": "This is Ubiquitin thioesterase OTUB1 protein, from Rat, contains 271 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B2RYG6", "organism_name": "Rat", "protein_name": "Ubiquitin thioesterase OTUB1", "length": 271, "firstPublicDate": "2008-09-02", "FUNCTION": "Plays a key non-catalytic role in DNA repair regulation by inhibiting activity of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites, Inhibits RNF168 independently of ubiquitin thioesterase activity by binding and inhibiting UBE2N/UBC13, the E2 partner of RNF168, thereby limiting spreading of 'Lys-63'-linked histone H2A and H2AX marks, Inhibition occurs by binding to free ubiquitin: free ubiquitin acts as an allosteric regulator that increases affinity for UBE2N/UBC13 and disrupts interaction with UBE2V1, The OTUB1-UBE2N/UBC13-free ubiquitin complex adopts a configuration that mimics a cleaved 'Lys48'-linked di-ubiquitin chain (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the peptidase C65 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDRGEGGTTNPHVFPEGSEPKVYLLYRPGHYDILYK", "length": 271, "molWeight": 31270, "crc64": "32F78EE1DC5FD679", "md5": "CABAB9323860D5A7D5B7FDC044B69874"}}
{"primaryAccession": "B3EWF4", "text": "This is Latartoxin-2a protein, from Spider, contains 109 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3EWF4", "organism_name": "Spider", "protein_name": "Latartoxin-2a", "length": 109, "firstPublicDate": "2013-04-03", "FUNCTION": "Insect toxin, Causes paralysis in larvae of C,vicina by depolarizing membranes at the neuromuscular junction", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 19 (CSTX) family, 11 (latartoxin) subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKVLVIIALCLVAFQSALSKKIENFESYIEDLKSEARECIPLYNDCTAFKYNNNCCKDPEKKYQYKCSCIVCKEGKEQCTCQRKETVESMMKCVRFVKKVGEKVIEKVG", "length": 109, "molWeight": 12585, "crc64": "E8D9D1A872BD6C28", "md5": "3D33E0B9DD5304ADEA1BAD3F81E5BEE1"}}
{"primaryAccession": "B3EWF5", "text": "This is Latartoxin-2b protein, from Spider, contains 111 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3EWF5", "organism_name": "Spider", "protein_name": "Latartoxin-2b", "length": 111, "firstPublicDate": "2013-04-03", "FUNCTION": "Insect toxin", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 19 (CSTX) family, 11 (latartoxin) subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKVLVIIALCFFILQTALSEDKYESFESYVEDLKSGNMKGEARECIPLYNDCKEFKYNNNCCKDPEKKYQYKCSCIMCEGGEEQCTCQRKETVENMMKCVRFVKKVVEKVG", "length": 111, "molWeight": 12948, "crc64": "D1098BE4BF76A298", "md5": "E5CA32862671DA03C3EC2A294EB98238"}}
{"primaryAccession": "B3EWF6", "text": "This is Latartoxin-2c protein, from Spider, contains 108 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3EWF6", "organism_name": "Spider", "protein_name": "Latartoxin-2c", "length": 108, "firstPublicDate": "2013-04-03", "FUNCTION": "Insect toxin", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 19 (CSTX) family, 11 (latartoxin) subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKVLVITALCFILLQNVLGEDTYEDLQNYIENLINENQDEARECVPLENDCTKLKYSNPCCKDEKKKYQYKCSCIVDKTEQCTCQRKETVEKMMKGMKYIKNLGKKIG", "length": 108, "molWeight": 12617, "crc64": "5011538231BF300F", "md5": "DA379CBF98E1CA032CECE27ABACEC814"}}
{"primaryAccession": "B8YG19", "text": "This is Bifunctional acetylxylan esterase/xylanase XynS20E protein, from Rumen fungus, contains 671 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B8YG19", "organism_name": "Rumen fungus", "protein_name": "Bifunctional acetylxylan esterase/xylanase XynS20E", "length": 671, "firstPublicDate": "2014-07-09", "FUNCTION": "Bifunctional acetylxylan esterase/xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose, Degrades xylan from acetylxylan, beechwood, birchwood, and oat spelt, and releases acetate from 4-methylumbelliferyl acetate and beta-D-xylose tetraacetate, No activity is observed against carboxy methyl cellulose, beta-glucan, p-nitrophenol acetate, p-nitrophenol laurate, p-nitrophenol myristate, p-nitrophenol, palmitate, or beta-naphthol acetate", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "In the C-terminal section; belongs to the glycosyl hydrolase 11 (cellulase G) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRLGVALSTIAVLLTATSARNLDKRQWGWPNFGGGNGGNGGNGGKTINDYKREQGAGRDIHVYAPSNLAPNSPLLLSLHGMDQDPNYQQSNTHWETLADSEGFVVVYPRGGTGMSTWDIQGTKDTQWVSQIIDQMKKEYNIDTKRVYLSGFSMGGMFTYHAMSQIANKIAAFAPCSGPNVFGASKAQRPVPIFHVHGTNDDVLNYQQVEGFLKNYRDQFHCPSQADTKTNYPNRENPNATLYTWGPCDKGVYIKHLKLQGRGHSPSSADIQDIWDFVSQWTVDGPVSASGNGGGNTTPTNPSTGGNGNGNGGGNTTPTNPSTGGNGNGNGGSTDKCSSNITKQGYKCCASNCEVVYTDSDGDWGVENDQWCGCGNRVTVGSGTCSAKILQQGYKCCPSGCIIYYTDEDGTWGVNGEEWCGCGSGSSSTGGGNDAPSSGSGYQGANGTNFCNNAKHSGESVTVTSNKVGDINGIGYELWADSGNNSATFYDDGSFSCSFQRAKDYLCRSGLSFDSTKTHKQIGHIYAEFKLVKQNIQNVDYSYVGIYGWTRNPLVEFYVVDNWLSQWRPGDWVGNKKHGDFTIGGAQYTVYENTRYGPSIDGDTNFKQYFSIRQQPRDCGTIDITAHFEQWEKLGMTMGKMHEAKVLGEAGSNNGGTSGTADFPFAKVYVKN", "length": 671, "molWeight": 72469, "crc64": "EC02F1D1A775640D", "md5": "B71D9EF0B46DD70A15F75FD562666C48"}}
{"primaryAccession": "B9DFZ0", "text": "This is Endonuclease III homolog 2, chloroplastic protein, from Mouse-ear cress, contains 386 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B9DFZ0", "organism_name": "Mouse-ear cress", "protein_name": "Endonuclease III homolog 2, chloroplastic", "length": 386, "firstPublicDate": "2014-04-16", "FUNCTION": "Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage, The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site, The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, Primarily recognizes and repairs oxidative base damage of pyrimidines", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the Nth/MutY family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MILTGAASTFPIVARVLNAMNRRMYAATTLSSAKSISAESLNLRSDSNSEAAHGASESETRVSLRKKRIKQDDLEPVKKCSARETKARKDMCGLPDIEDSPYKKTNGTASSRTRKLNSYIKSTEASPSASSIKTAGLGIPPENWEKVLEGIRKMKPSEEAPVNAVECDRTGSFLPPKERRFYVLIGTLLSSQTKEHITGAAVERLHQNGLLTPEAIDKADESTIKELIYPVGFYTRKATNVKKVAKICLMEYDGDIPRTLEELLSLPGVGPKIAHLVLHVAWNDVQGICVDTHVHRICNRLGWVSKPGTKQKTSSPEETRVALQQWLPKGEWVAINFLLVGFGQTICTPLRPHCGTCSITEICPSAFKETPSTSSKLKKSIKSKKL", "length": 386, "molWeight": 42415, "crc64": "814269503D6CF14A", "md5": "0D283452BCADD7EF85CB1ADBB468B189"}}
{"primaryAccession": "C7AU21", "text": "This is Beta-carotene isomerase D27, chloroplastic protein, from Rice, contains 278 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C7AU21", "organism_name": "Rice", "protein_name": "Beta-carotene isomerase D27, chloroplastic", "length": 278, "firstPublicDate": "2013-04-03", "FUNCTION": "Involved in strigolactones biosynthesis by catalyzing the isomerization of the C9-C10 double bond in all-trans-beta-carotene leading to 9-cis-beta-carotene and providing the substrate for CCD7, Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signals that stimulate hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "METTTLVLLLPHGGAGGVRPAAAATAKRSYVMRRCCSTVRAVMARPQEAPASAPAKKTETAAMMSTVQTETAAAPPATVYRDSWFDKLAIGYLSRNLQEASGLKNEKDGYESLIDAALAISRIFSLDKQSEIVTQALERALPSYILTMIKVMMPPSRFSREYFAAFTTIFFPWLVGPCEVMESEVEGRKEKNVVYIPKCRFLESTNCVGMCTNLCKIPCQKFIQDSLGMKVYMSPNFEDMSCEMIFGQQPPEDDPALKQPCFRTKCVAKQNHGVNCSI", "length": 278, "molWeight": 30759, "crc64": "B82A9C68CDBC8F2F", "md5": "5CB33068E04D6FB8044F61F6E3AB7716"}}
{"primaryAccession": "C9JLW8", "text": "This is Mapk-regulated corepressor-interacting protein 1 protein, from Human, contains 97 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C9JLW8", "organism_name": "Human", "protein_name": "Mapk-regulated corepressor-interacting protein 1", "length": 97, "firstPublicDate": "2010-05-18", "FUNCTION": "The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition, Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s), When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition (PubMed:25728771)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCRIP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTSSPVSRVVYNGKRTSSPRSPPSSSEIFTPAHEENVRFIYEAWQGVERDLRGQVPGGERGLVEEYVEKVPNPSLKTFKPIDLSDLKRRSTQDAKKS", "length": 97, "molWeight": 10920, "crc64": "D92176E755159A81", "md5": "A6ECC13F106251C5F37B7A443634B511"}}
{"primaryAccession": "D0VWU3", "text": "This is Laccase protein, from White-rot fungus, contains 499 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D0VWU3", "organism_name": "White-rot fungus", "protein_name": "Laccase", "length": 499, "firstPublicDate": "2010-11-30", "FUNCTION": "Lignin degradation and detoxification of lignin-derived products", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the multicopper oxidase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "AVGPVADNTITDAATSPDGFSRQAVVVNGVTPGPLVAGNIGDRFQLNVIDNLTNHTMLKTTSVHWHGFFQQGTNWADGPAFINQCPISPGHSFLYDFQVPNQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPHASRYDVDNDDTVITLADWYHTAAKLGPRFPAGADATLINGKGRAPSDTSAELSVIKVTKGKRYRFRLVSLSCDPNFTFSIDGHNLTIIEVDSSNSQPLSVDSIQIFAAQRYSFVLNANQAVDNYWIRANPNFGNVGFNGGINSAILRYDGAPAVEPTTNQTTSVKPLNEVNLHPLVSTPVPGSPSSGGVDKAINMAFNFNGSNFFINGASFVPPSVPVLLQILSGAQTAQDLLPSGSVYVLPSNASIEISFPATAAAPGAPHPFHLHGHTFAVVRSAGSTVYNYSNPIFRDVVSTGTPAAGDNVTIRFLTNNPGPWFLHCHIDFHLEGGFAVVQAEDVPDVKATNPVPQAWSDLCPTYDANAPSDQ", "length": 499, "molWeight": 53451, "crc64": "F018B0357333CF33", "md5": "5497C9A3AFFDBB6FE456F0E941FDA602"}}
{"primaryAccession": "D0VWV4", "text": "This is Succinate dehydrogenase cytochrome b560 subunit, mitochondrial protein, from Pig, contains 169 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D0VWV4", "organism_name": "Pig", "protein_name": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "length": 169, "firstPublicDate": "2010-03-02", "FUNCTION": "Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the cytochrome b560 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAALLLRHVGRHCLRAHLSPQLCIRNAVPLGTTAKEEMERFWNKNLGSNRPLSPHITIYRWSLPMAMSICHRGTGIALSAGVSLFGLSALLLPGNFESHLELVKSLCLGPTLIYTAKFGIVFPLMYHTWNGIRHLIWDLGKGLTIPQLTQSGVVVLILTVLSSVGLAAM", "length": 169, "molWeight": 18518, "crc64": "42EB611C1DCDF0A5", "md5": "D6AB5DF35DC81BF07C79E19BCACB36D4"}}
{"primaryAccession": "D3Z3K2", "text": "This is E3 ubiquitin-protein ligase CCNB1IP1 protein, from Mouse, contains 276 amino acids, has 1 RING-type; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [10, 52], "description": "RING-type; atypical", "keyword_description": "Zinc finger", "textural_description": "RING-type; atypical Zinc finger"}], "meta_data": {"primaryAccession": "D3Z3K2", "organism_name": "Mouse", "protein_name": "E3 ubiquitin-protein ligase CCNB1IP1", "length": 276, "firstPublicDate": "2014-03-19", "FUNCTION": "Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites, Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites, Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over, Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase, Overexpression causes delayed entry into mitosis", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"RING-type; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLDIVRTELSPSEEYKAMVLAGLRPEVVLDISSRALAFWTYQVHQERLYQEYNFSKAENHLKQMEKMYMQQIQSKNIELTSMKGEVISMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDSLRLRNITIASQEGSLEPGMIPQSGVFGFPPGNNSKFSLDHIPVGNQGGGDEDVQFRPFFVCSPTAPEPINNFFSFASPSHEAEQQVCSRAFKAKRI", "length": 276, "molWeight": 31386, "crc64": "8677CFEC187C1465", "md5": "43FD6DFF822EB15A8BAFA9E7EC1787C1"}}
{"primaryAccession": "D3ZAW2", "text": "This is Phosphatidylserine decarboxylase proenzyme, mitochondrial protein, from Rat, contains 406 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D3ZAW2", "organism_name": "Rat", "protein_name": "Phosphatidylserine decarboxylase proenzyme, mitochondrial", "length": 406, "firstPublicDate": "2016-02-17", "FUNCTION": "Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer), Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine, May be involved in lipid droplet biogenesis at the endoplasmic reticulum membrane (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the phosphatidylserine decarboxylase family, PSD-B subfamily, Eukaryotic type I sub-subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAVAGGRGCVRSLREGVLWRSSPCHCDYTATRHFLGALQKLPLQAWVRKVHTAPLRTLFLLRPVPILLAAGGGYAGYRQYEKYRERQLEKLGLEIPPKLASHWEVSLYKSVPTRLLSRACGRLNQVELPSWLRRPVYSLYIWTFGVNMTEAAVEDLQHYRNLSEFFRRKLKPQARPVCGLHSVISPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGPRACTEDLPFPPASSCDSFRNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTVSHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDQDLHTNSPSYSKGSYNDLSFVTHANKEGIPMRKGEPLGEFNLGSTIVLIFEAPKDFNFRLKAGQKILFGEALGSL", "length": 406, "molWeight": 45824, "crc64": "5358A6A2A6D72EE7", "md5": "4BB8AAC8F0B26BEF4E4171E21E26904B"}}
{"primaryAccession": "F4HQA1", "text": "This is Protein PAF1 homolog protein, from Mouse-ear cress, contains 589 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4HQA1", "organism_name": "Mouse-ear cress", "protein_name": "Protein PAF1 homolog", "length": 589, "firstPublicDate": "2015-04-29", "FUNCTION": "Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3) (PubMed:20363855), Involved in regulation of flowering time, Required for the expression of the flowering repressors and MAD-box genes FLC, AGL27/FLM and AGL31/MAF2, Required for histone H3 trimethylation on 'Lys-4' H3K4me3 at the FLC and AGL27/FLM loci (PubMed:15520273), Involved in the control of seed dormancy and germination (PubMed:21799800)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the PAF1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASYRPPYPPLPQPPSQNSLAPPPPPPSLPPPVPPPPPSHQPYSYPPPPPPPPHAYYQQGPHYPQFNQLQAPPPPPPPSAPPPLVPDPPRHQGPNDHEKGASKQVGRRERAKPDPSKHHHRSHLPHSKKIETEEERRLRKKRELEKQRQDEKHRQQMKNSHKSQMPKGHTEEKKPTPLLTTDRVENRLKKPTTFICKLKFRNELPDPSAQLKLMTIKRDKDQFTKYTITSLEKLWKPKIFVEPDLGIPLDLLDLSVYNPPKVKAPLAPEDEELLRDDDAVTPIKKDGIRRKERPTDKGMSWLVKTQYISSINNESARQSLTEKQAKELREMKGGINILHNLNNRERQIKDIEASFEACKSRPVHATNKNLQPVEVLPLLPYFDRYDEQFVVANFDGAPIADSEFFGKLDPSIRDAHESRAILKSYVVAGSDTANPEKFLAYMVPSLDELSKDIHDENEEISYTWVREYLWDVQPNANDPGTYLVSFDNGTASYLPLPMRLNLRKKRAREGRSSDEIEHFPVPSRVTVRRRSTVSVIEHKDSGVYSSRVGASSSKMRRLEDEGGLGRSWKHEPEQDANQYSDGNEDDYSE", "length": 589, "molWeight": 67338, "crc64": "8909E557DED725A0", "md5": "D211653E665E2A04F3E78EC04DCA74F3"}}
{"primaryAccession": "F4I2J8", "text": "This is Splicing factor Cactin protein, from Mouse-ear cress, contains 716 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4I2J8", "organism_name": "Mouse-ear cress", "protein_name": "Splicing factor Cactin", "length": 716, "firstPublicDate": "2014-07-09", "FUNCTION": "Plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (By similarity), Required for embryogenesis (PubMed:23454656)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CACTIN family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGSHGKGKRDRSGRQKKRRDESESGSESESYTSDSDGSDDLSPPRSSRRKKGSSSRRTRRRSSSDDSSDSDGGRKSKKRSSSKDYSEEKVTEYMSKKAQKKALRAAKKLKTQSVSGYSNDSNPFGDSNLTETFVWRKKIEKDVHRGVPLEEFSVKAEKRRHRERMTEVEKVKKRREERAVEKARHEEEMALLARERARAEFHDWEKKEEEFHFDQSKVRSEIRLREGRLKPIDVLCKHLDGSDDLDIELSEPYMVFKKKKVRIGIWLNFQLSITNVYVEAEYKNDSACLLLRSRVDILLNKGLTVKDMEELRDDIKMYLDLDRATPTRVQYWEALIVVCDWELAEARKRDALDRARVRGEEPPAELLAQERGLHAGVEADVRKLLDGKTHAELVELQLDIESQLRSGSAKVVEYWEAVLKRLEIYKAKACLKEIHAEMLRRHLHRLEQLSEGEDDVEVNPGLTRVVEENEEEINDTNLSDAEEAFSPEPVAEEEEADEAAEAAGSFSPELMHGDDREEAIDPEEDKKLLQMKRMIVLEKQKKRLKEAMDSKPAPVEDNLELKAMKAMGAMEEGDAIFGSNAEVNLDSEVYWWHDKYRPRKPKYFNRVHTGYEWNKYNQTHYDHDNPPPKIVQGYKFNIFYPDLVDKIKAPIYTIEKDGTSAETCMIRFHAGPPYEDIAFRIVNKEWEYSHKKGFKCTFERGILHLYFNFKRHRYRR", "length": 716, "molWeight": 83434, "crc64": "22AB9CA80AB883A0", "md5": "21D73F1D96560AB12526E5F15A145853"}}
{"primaryAccession": "F4I443", "text": "This is BRCA1-associated RING domain protein 1 protein, from Mouse-ear cress, contains 714 amino acids, has 1 RING-type Zinc finger, has 1 C2HC pre-PHD-type Zinc finger, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [25, 63], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [331, 382], "description": "C2HC pre-PHD-type", "keyword_description": "Zinc finger", "textural_description": "C2HC pre-PHD-type Zinc finger"}, {"location": [402, 451], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "F4I443", "organism_name": "Mouse-ear cress", "protein_name": "BRCA1-associated RING domain protein 1", "length": 714, "firstPublicDate": "2015-04-29", "FUNCTION": "Binds specifically to H3K4me3 regions of target genes (e,g, WUS and WOX5) promoters to repress their transcription via chromatin remodeling, Required for the shoot apical meristem (SAM) organization and maintenance, by confining WUS expression to the organizing center, and for the quiescent center (QC) development in the root apical meristem (RAM), by repressing WOX5 expression in the root proximal meristem (PubMed:18591352, PubMed:25631790), Plays a role in DNA repair and in cell-cycle control, Required for the repair of DNA double-strand breaks (DSBs), both natural and induced by genotoxic stress, by homologous recombination (HR) (PubMed:16957774)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"RING-type Zinc finger": 1, "C2HC pre-PHD-type Zinc finger": 1, "PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAEFTNMLMNPWVLHLQKLELELKCPLCLKLLNRPVLLPCDHVFCDSCVHKSSQVESGCPVCKSKHPKKARRDLRFMESVISIYKSLNAAVSVHLPQLQIPNDCNYKNDALNNSNSPKHGESEDSEMTDKDVSKRSGGTDSSSRDGSPLPTSEESDPRPKHQDWTEKQLSDHLLLYEFESEYDAANHTPESYTEQAAKNVRDITASEQPSNAARKRICGDSFIQESSPNPKTQDPTLLRLMESLRSDDPTDYVKAQNHQQLPKSHTEQDSKRKRDITASDAMENHLKVPKRENNLMQKSADIDCNGKCSANSDDQLSEKISKALEQTSSNITICGFCQSARVSEATGEMLHYSRGRPVDGDDIFRSNVIHVHSACIEWAPQVYYEGDTVKNLKAELARGMKIKCTKCSLKGAALGCFVKSCRRSYHVPCAREISRCRWDYEDFLLLCPAHSSVKFPNEKSGHRVSRAEPLPKINPAELCSLEQTPAFTKELVLCGSALSKSDKKLMESLAVRFNATISRYWNPSVTHVIASTDEKGACTRTLKVLMGILNGKWIINAAWMKASLKASQPVDEEPFEIQIDTQGCQDGPKTARLRAETNKPKLFEGLKFYFFGDFYKGYKEDLQNLVKVAGGTILNTEDELGAESSNNVNDQRSSSIVVYNIDPPHGCALGEEVTIIWQRANDAEALASQTGSRLVGHTWVLESIAGYKLHPVIG", "length": 714, "molWeight": 79690, "crc64": "9CE32995288E50CE", "md5": "BE11369C59C6073E95955B790EB0627E"}}
{"primaryAccession": "F4I5N6", "text": "This is CRIB domain-containing protein RIC3 protein, from Mouse-ear cress, contains 220 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4I5N6", "organism_name": "Mouse-ear cress", "protein_name": "CRIB domain-containing protein RIC3", "length": 220, "firstPublicDate": "2013-06-26", "FUNCTION": "Functions as downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family, Participates in the propagation of ROP GTPase signals in specific cellular responses, Functions as downstream effector of ARAC11/ROP1 to activate calcium signaling that leads to F-actin disassembly associated with exocytosis in the tip of the growing pollen tube, Counteracts the ARAC11/ROP1-RIC4 pathway, which promotes apical F-actin assembly associated with vesicle accumulation, to control actin dynamics and pollen tube apical growth", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATVKGLLKGLRYITQIFDEEKDKDMQIGFPTDVKHVAHIGSDGPATNVPSWMGDFKPQENENGQVVSRADANNNQIGEGVGLQELLPPTDKPKHKKTRRKSETVSQNGSPPRRNSSASASDMQPKNTRRHHRSRHGSIDSSNDPSVRRRRVVSVTTNDMEGSYPLSDSSTHSRKSTSRHRKPKGSGGGELSMKKTKGKTENPIVESVDTCNDNNISDKE", "length": 220, "molWeight": 24256, "crc64": "A15369C2ECFFDCA2", "md5": "42BFC53FA8E159B426F827661682462F"}}
{"primaryAccession": "F4IPE3", "text": "This is Zinc finger protein SHOOT GRAVITROPISM 5 protein, from Mouse-ear cress, contains 445 amino acids, has 3 C2H2-type Zinc finger, has 1 CCHC-type 2; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [73, 95], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [115, 145], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [151, 178], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [178, 201], "description": "CCHC-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "CCHC-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "F4IPE3", "organism_name": "Mouse-ear cress", "protein_name": "Zinc finger protein SHOOT GRAVITROPISM 5", "length": 445, "firstPublicDate": "2014-05-14", "FUNCTION": "Transcription factor involved in inflorescence stems gravitropism, probably by regulating starch accumulation in amyloplasts of graviperceptive cells, Required for stem circumnutation movements, Regulates lateral organ morphogenesis and gravitropic responses (PubMed:24039602), Acts cooperatively with IDD16 to control silique and branche orientation (PubMed:24039602), Involved in the establishment of auxin gradients through the regulation of auxin biosynthesis and transport (PubMed:24039602)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 3, "CCHC-type 2; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRTDQVMLSNKNTNTCCVVSSSSSDPFLSSSENGVTTTNTSTQKRKRRPAGTPDPDAEVVSLSPRTLLESDRYICEICNQGFQRDQNLQMHRRRHKVPWKLLKRDNNIEVKKRVYVCPEPTCLHHNPCHALGDLVGIKKHFRRKHSNHKQWVCERCSKGYAVQSDYKAHLKTCGTRGHSCDCGRVFSRVESFIEHQDNCSARRVHREPPRPPQTAVTVPACSSRTASTVSTPSSETNYGGTVAVTTPQPLEGRPIHQRISSSILTNSSNNLNLELQLLPLSSNQNPNQENQQQKVKEPSHHHNHNHDTTNLNLSIAPSSSYQHYNNFDRIKEIMASEQIMKIAMKEKAYAEEAKREAKRQREIAENEFANAKKIRQKAQAELERAKFLKEQSMKKISSTIMQVTCQTCKGQFQAVAVPAATADETSLVVSYMSSANTDGELENGF", "length": 445, "molWeight": 50140, "crc64": "C310B37E9376AC60", "md5": "7E64CB305612773DF8DDFF12F0E6DDAE"}}
{"primaryAccession": "F4IVV0", "text": "This is CRIB domain-containing protein RIC1 protein, from Mouse-ear cress, contains 224 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4IVV0", "organism_name": "Mouse-ear cress", "protein_name": "CRIB domain-containing protein RIC1", "length": 224, "firstPublicDate": "2013-06-26", "FUNCTION": "Functions as downstream effector of Rho-related GTP binding proteins of the 'Rho of Plants' (ROPs) family, Participates in the propagation of ROP GTPase signals in specific cellular responses, Required for cortical microtubule organization, Promotes microtubule bundling and formation of well-ordered microtubule arrays in the neck region of pavement cells, This restricts cell lateral expansion to generate the narrow neck morphology of pavement cells, Its function is inhibited when it interacts with activated ARAC4/ROP2, Represses ARAC4/ROP2 activation and antagonizes the RIC4-actin pathway that promotes the assembly of cortical actin microfilaments, Acts as downstream effector of ARAC3/ROP6 which functions in a signaling pathway that negatively regulates clathrin-mediated endocytosis and internalization of PIN1 and PIN2, Required for the asymmetric auxin distribution during root gravitropism and vascular patterning, Positively regulates auxin responses, but negatively regulates ABA responses during lateral root development and primary root elongation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATTMKGLLKGLRYITQIFDEEKEQEMQIGFPTDVKHVAHIGSDGPTNTTPSWMNDFKTQEHEKGQVVSRGNSNKYNPQGTNQRGAGLKELLPSNTNEKPKQKTRRKPGGAASPNHNGSPPRKSSGNAASSDEPSKHSRHNRSAHGSTDSSNDQEPSVRRRRGGIPAPDTEVPNQIPDGSAPPRKATSRPRKLKGSSAGGEGSIKKSSKGKPENSVDTTCNDII", "length": 224, "molWeight": 24140, "crc64": "7679F15DA4C3E133", "md5": "262BF13312C1027827C7822EA5D086BA"}}
{"primaryAccession": "F4IW47", "text": "This is Transketolase-2, chloroplastic protein, from Mouse-ear cress, contains 741 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4IW47", "organism_name": "Mouse-ear cress", "protein_name": "Transketolase-2, chloroplastic", "length": 741, "firstPublicDate": "2013-03-06", "FUNCTION": "Catalyzes the reversible transfer of a two-carbon ketol group from fructose-6-phosphate or sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to yield xylulose-5-phosphate and erythrose-4-phosphate or ribose-5-phosphate, respectively (By similarity), Could act as a stress sensor involved in adaptation process", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the transketolase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASTSSLALSQALLTRAISHNGSENCVSIPAFSALKSTSPRTSGTISSRRRNASTISHSLRPLVRAAAVEAIVTSSDSSLVDKSVNTIRFLAIDAVEKAKSGHPGLPMGCAPMSHILYDEVMKYNPKNPYWFNRDRFVLSAGHGCMLQYALLHLAGYDSVREEDLKSFRQWGSKTPGHPENFETPGVEATTGPLGQGIANAVGLALAEKHLAARFNKPDNEIVDHYTYSILGDGCQMEGISNEVCSLAGHWGLGKLIAFYDDNHISIDGDTDIAFTESVDKRFEALGWHVIWVKNGNNGYDEIRAAIREAKAVTDKPTLIKVTTTIGYGSPNKANSYSVHGAALGEKEVEATRNNLGWPYEPFHVPEDVKSHWSRHTPEGAALEADWNAKFAAYEKKYPEEAAELKSIISGELPVGWEKALPTYTPDSPGDATRNLSQQCLNALAKAVPGFLGGSADLASSNMTMLKAFGNFQKATPEERNLRFGVREHGMGAICNGIALHSPGFIPYCATFFVFTDYMRAAMRISALSEAGVIYVMTHDSIGLGEDGPTHQPIEHLSSFRAMPNIMMFRPADGNETAGAYKIAVTKRKTPSVLALSRQKLPQLPGTSIESVEKGGYTISDNSTGNKPDVILIGTGSELEIAAQAAEKLREQGKSVRVVSFVCWELFDEQSDAYKESVLPSDVSARVSIEAGSTFGWGKIVGGKGKSIGIDTFGASAPAGKLYKEFGITIEAMVEAAKSLI", "length": 741, "molWeight": 79922, "crc64": "C712DFDE2C7D63C6", "md5": "38B65474866498E4AE4BC00F57843006"}}
{"primaryAccession": "F4JCC1", "text": "This is Pre-mRNA-processing protein 40B protein, from Mouse-ear cress, contains 992 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4JCC1", "organism_name": "Mouse-ear cress", "protein_name": "Pre-mRNA-processing protein 40B", "length": 992, "firstPublicDate": "2012-07-11", "FUNCTION": "Binds the phosphorylated C-terminal domain (CTD) of the largest subunit of RNA polymerase II and functions as a scaffold for RNA processing machineries (PubMed:10907853), May be involved in pre-mRNA splicing (Probable)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the PRPF40 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MANNHQYPGIQPFQHPNASSIDLPRGFAPPMNFQFLPTIQAPQSEQVARLSSQNFQCVGRGGTVLSIGYPPQSYAPQLLQSMHHSHERPSQLNQVQVQHVPLGPPTLISQPNVSIASGTSLHQPYVQTPDIGMPGFGGPRALFSYPSATSYEGSRVPPQVTGPSIHSQAQQRASIIHTSAESSIMNPTFEQPKAAFLKPLPSQKALTDWVEHTSADGRKYFFNKRTKKSTWEKPVELMTLFERADARTDWKEHSSPDGRKYYYNKITKQSTWTMPEEMKIVREQAEIASVQGPHAEGIIDASEVLTRSDTASTAAPTGLPSQTSTSEGVEKLTLTSDLKQPASVPGSSSPVENVDRVQMSADETSQLCDTSETDGLSVPVTETSAATLVEKDEISVGNSGDSDDMSTKNANQGSGSGPKESQKPMVESEKVESQTEEKQIHQESFSFNNKLEAVDVFKSLLKSAKVGSDWTWEQAMREIINDKRYGALRTLGERKQAFNEFLLQTKRAAEEERLARQKKLYEDFKRMLEECVELTPSTRWSKTVTMFEDDERFKALEREKDRRNIFEDHVSELKEKGRVKALEDRKRNIIEYKRFLESCNFIKPNSQWRKVQDRLEVDERCSRLEKIDQLEIFQEYLRDLEREEEEKKKIQKEELKKVERKHRDEFHGLLDEHIATGELTAKTIWRDYLMKVKDLPVYSAIASNSSGATPKDLFEDAVEDLKKRDHELKSQIKDVLKLRKVNLSAGSTFDEFKVSISEDIGFPLIPDVRLKLVFDDLLERAKEKEEKEARKQTRQTEKLVDMLRSFKDITASSSWEELKHLVEGSEKCSTIGDESFRKRCFEDYVSLLKEQSNRIKQNKKVPEDVREEHDKGRDKYGREKDRVRERDSDDHHKKGAAGKYNHDMNEPHGKERRRSGRDSHNRHRERHTSVKENDTDHFKESHKAGGGHKKSRHQRGWVSEAEVEGKEKRRRKEEAREHTKEEELEDGECGRY", "length": 992, "molWeight": 113569, "crc64": "7061088BF30A7443", "md5": "653BFD8A1B837A4A051C05AE51F3955E"}}
{"primaryAccession": "F4JI44", "text": "This is Nodulin homeobox protein, from Mouse-ear cress, contains 913 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4JI44", "organism_name": "Mouse-ear cress", "protein_name": "Nodulin homeobox", "length": 913, "firstPublicDate": "2015-10-14", "FUNCTION": "Regulates COOLAIR, a set of antisense transcripts originating from the 3' end of FLOWERING LOCUS C (FLC), Associates with single-stranded DNA that is part of an RNA-DNA hybrid, or R-loop, that covers the COOLAIR promoter, R-loop stabilization mediated by NDX inhibits COOLAIR transcription, which in turn modifies FLC expression", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVRLLQPKHMVQAVNALHWRNSVEFHKLLKDNGDFSICFNSEQVLPQKISVEKMVKMLPRHLIAVVMTPNKDGKSRYILCGIRLLQTLCDLTPRNAKLEQVLLDDVKLSAQMIDLVILVIIALGRNRKESCNSNKESLLEATLVASCLHLFHGFISPNSQDLVLVLLAHPRVDVFIDSAFGAVLNVVISLKAKLLYRQTDSPKKLGASSVEEVNFHCQQAEAALQFLHSLCQHKPFRERVAKNKELCGKGGVLRLAQSILSLTITPEFVGATVTIASTSRMKAKVLSILQHLFEAESVSFLDEVANAGNLHLAKTVASEVLKLLRLGLSKASMATASPDYPMGFVLLNAMRLADVLTDDSNFRSFFTEHFSMVLSAVFCLSHGDFLSMLCSSDLSSREDDANVDYDLFKSAGWILSVFSSSGQSVTPQFKLSLQNNLTMSSYAHQRTSLFIKMIANLHCFVPNVCQEQDRNRFIQNVMSGLRKDPSSILIKMLPGSSYTPVAQRGTGVCRNLGSLLRHAESLIPSSLNEEDFLLLRVFCDQLQPLIHSEFEESQVQVKVKKLFALLYIGFTILWLICLVTLIQDIEGRGGNLSGKLKELLNLNNEEASEDCDVRVEGVMTKQGVNEEIDTVERLKESDADASNLETSGSDTSSNRGKGLVEEGELVQNMSKRFKGSASGEVKEDEKSETFLVFEKQKKKRKRSIMNADQMGMIEKALAEEPDLQRNSASRQLWADKISQKGSEVITSSQLKNWLNNRKAKLARANKQTGPAHDNNSSGDLPESPGDENTWQQKPSTPIKDQTVTETPKTGENLMRTSSSSEEGIKQGQQVRLMDERGDEIGKGTVLRTDGEWNGLSLETRQICVVDVMELSESYDGSKKMIPYGSDDVGRTFTEANSRFGVMRVAWDVNKLQY", "length": 913, "molWeight": 101566, "crc64": "BA8EE74E8EA271A3", "md5": "EE2A9C805C107DB9E797E8D9F8A8CACC"}}
{"primaryAccession": "F4JL28", "text": "This is Chromatin remodeling protein EBS protein, from Mouse-ear cress, contains 234 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [146, 197], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "F4JL28", "organism_name": "Mouse-ear cress", "protein_name": "Chromatin remodeling protein EBS", "length": 234, "firstPublicDate": "2015-12-09", "FUNCTION": "Chromatin remodeling factor that binds to methylated histone (e,g, H3K4me2/3) to prevent their acetylation (e,g, H3K9K14Ac), likely by recruiting histone deacetylase (HDAC) complexes, and thus regulating the transcription of target genes (PubMed:25281686), Negative regulator in developmental processes in a gibberellic acid- (GA-) dependent manner, such as germination, flowering induction, and flower organ specification, probably by modulating developmental gene expression (PubMed:11340178, PubMed:25281686), Involved in the chromatin-mediated repression of floral initiation and controls genes regulating flowering (PubMed:25281686), Negatively regulates the expression of the floral integrator FT epigenetically, by preventing high levels of H3 acetylation, thus maintaining an inactive chromatin conformation at FT locus (PubMed:25281686, PubMed:12837946)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SHL1/EBS protein family", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAKTRPGVASKIKTGRKELDSYTIKGTNKVVRAGDCVLMRPSDAGKPPYVARVEKIEADARNNVKVHCRWYYRPEESLGGRRQFHGAKELFLSDHFDVQSAHTIEGKCIVHTFKNYTRLENVGAEDYYCRFEYKAATGAFTPDRVAVYCKCEMPYNPDDLMVQCEGCKDWYHPACVGMTIEEAKKLDHFVCAECSSDDDVKKSQNGFTSSPADDVKVRLSLFSHLLYRCSITYL", "length": 234, "molWeight": 26566, "crc64": "3552E498E0FDD583", "md5": "34CB33FDFA8B6F7AED3EF2DC8A9DAB57"}}
{"primaryAccession": "F4JYE9", "text": "This is Dihydrofolate synthetase protein, from Mouse-ear cress, contains 530 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4JYE9", "organism_name": "Mouse-ear cress", "protein_name": "Dihydrofolate synthetase", "length": 530, "firstPublicDate": "2015-10-14", "FUNCTION": "Conversion of folates to polyglutamate derivatives, including tetrahydrofolate (PubMed:11752472, PubMed:12535338), Required during embryogenesis; from maternal tissues until the globular stage, and from the embryo after the globular stage (PubMed:12535338)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the folylpolyglutamate synthase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRTLWNHFSTISYIKISPRMRRISAANLISNRNLSTISSTEDPELRDFVGFLESLKNYEKSGVPKGAGTDSDDGFDLGRMKRLMLRLRNPHYKYKVVHVAGTKGKGSTSAFLSNILRAGGYSVGCYSSPHILSIKERISCNGEPVSASTLNDLFYSVKPILEQSIQEENGSLSHFEILTGIAFSLFEKENVDIAVIEAGLGGARDATNVIESSNLAASVITTIGEEHMAALGGSLESIAEAKSGIIKHGRPVVLGGPFLPHIEGILRSKAASVSSSVILASNIGSSSSIKGIINKNGIGLCQSCDIVIQNEKDDQPIVELSDVNLRMLGHHQLQNAVTATCVSLCLRDQGCGRVTDEAIRIGLENTRLLGRSQFLTPKEAETLLLPGATVLLDGAHTKESARALKEMIKKDFPEKRLVFVVAMASDKDHVSFAKELLSGLKPEAVILTEADIGGGKIRSTESSVLKESWIKAADELGSRSMEASENKTVLGSLKLAYKILSDDTTSSDSGMVIVTGSLHIVSSVLASLQH", "length": 530, "molWeight": 56904, "crc64": "62F2FE8F8AF5A3CB", "md5": "26B69A59D7AF45CB162DBF68C1689BB0"}}
{"primaryAccession": "F4K2R6", "text": "This is Calmodulin-binding protein 60 G protein, from Mouse-ear cress, contains 563 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4K2R6", "organism_name": "Mouse-ear cress", "protein_name": "Calmodulin-binding protein 60 G", "length": 563, "firstPublicDate": "2015-05-27", "FUNCTION": "Transcription activator that binds DNA in a sequence-specific manner, 5'-GAAATTTTGG-3', to promote the expression of target genes (PubMed:20921422, PubMed:21615571, PubMed:23153277, PubMed:29757140), Recruited to the promoter of ICS1 and other defense-related genes (e,g, PR1, PR2 and EDS5) in response to both biotic (e,g, Pseudomonas syringae pv, maculicola ES4326, P, syringae pv, tomato DC3000, and microbe-associated molecular patterns (MAMPs) such as flg22) and abiotic stresses (e,g, UV-B, drought and abscisic acid), thus triggering rapid defense responses by stimulating salicylic acid (SA) biosynthesis, Involved in basal and systemic acquired resistance to P, syringae and Hyaloperonospora arabidopsidis (PubMed:20921422, PubMed:21615571, PubMed:22466450, PubMed:19214217), Mediates resistance to drought and sensitivity to abscisic acid (ABA), especially for ABA-mediated signaling process that regulates early seedling growth (PubMed:22466450)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the plant ACBP60 protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKIRNSPSFHGGSGYSVFRARNLTFKKVVKKVMRDQSNNQFMIQMENMIRRIVREEIQRSLQPFLSSSCVSMERSRSETPSSRSRLKLCFINSPPSSIFTGSKIEAEDGSPLVIELVDATTNTLVSTGPFSSSRVELVPLNADFTEESWTVEGFNRNILTQREGKRPLLTGDLTVMLKNGVGVITGDIAFSDNSSWTRSRKFRLGAKLTGDGAVEARSEAFGCRDQRGESYKKHHPPCPSDEVWRLEKIAKDGVSATRLAERKILTVKDFRRLYTVNRNELHNIIGAGVSKKTWNTIVSHAMDCVLDETECYIYNANTPGVTLLFNSVYELIRVSFNGNDIQNLDQPILDQLKAEAYQNLNRITAVNDRTFVGHPQRSLQCPQDPGFVVTCSGSQHIDFQGSLDPSSSSMALCHKASSSTVHPDVLMSFDNSSTARFHIDKKFLPTFGNSFKVSELDQVHGKSQTVVTKGCIENNEEDENAFSYHHHDDMTSSWSPGTHQAVETMFLTVSETEEAGMFDVHFANVNLGSPRARWCKVKAAFKVRAAFKEVRRHTTARNPREGL", "length": 563, "molWeight": 63068, "crc64": "4FD1D2A0FE6ED630", "md5": "74F92B8D6E93F0B3BF5534EF4C7D4BCF"}}
{"primaryAccession": "F4KFS7", "text": "This is Membrane protein of ER body 2 protein, from Mouse-ear cress, contains 550 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4KFS7", "organism_name": "Mouse-ear cress", "protein_name": "Membrane protein of ER body 2", "length": 550, "firstPublicDate": "2014-10-01", "FUNCTION": "May sequester excess cytosolic iron and manganese into endoplasmic reticulum to reduce metal ion toxicity, Not essential for the accumulation of ER body components, including PYK10", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the CCC1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEKSNQPVHVTLSELKDGDKEIVDAEFLVDLLESYRFGKDNVPAREFRSKAAATAPAPVNTTEIELEEDNDGSQAQGNNSVSESTSSLFSDSDPIVLESTVSETGSNEESETGSNEENGNNWLESSSTNLPNVENKRQRNGEDCEIEEEEENNERSLSDSEEKSNLEKLLGTQENYELGNEDEEKNERSSSDSEEKSNLENLLATQENYELYCPSCSTCITRNVVLKKRKRGKHVNSSLDLKPDIPVVEPDEPSDIEEMESPVKVYVPETRIEDDQEDKEGTIFTCLVCDLKYFIRLGTKFLQLDYIRGKPVEKSVEEYIDVRKSINTTQSPPQIQPDGERFAIELLKSTVYGGLTETITSLGVVSSASASGSSTMNILALAVANLAGGLIVLAQNFQDLRNSSDQEKDRYEELLGRRTKSRIHILVAVMSYIFFGLIPPLVYAFSFYETGIKNYKLISVFLGSLVCVILLGSIKVYVRKPTNSCGSTKAYLKSAAYYTSIVVASCGISYVVGDIMGEYIEKLSLVGLDQISITSPCYGIKPEECRFTSF", "length": 550, "molWeight": 61046, "crc64": "9F6E6C92E8FA2358", "md5": "48BAA22483C3AA39D56B2E09C2531A9D"}}
{"primaryAccession": "F7BJB9", "text": "This is MORC family CW-type zinc finger protein 3 protein, from Mouse, contains 942 amino acids, has 1 CW-type Zinc finger, is soluble, locates in Nucleus.", "functionDomainRange": [{"location": [404, 454], "description": "CW-type", "keyword_description": "Zinc finger", "textural_description": "CW-type Zinc finger"}], "meta_data": {"primaryAccession": "F7BJB9", "organism_name": "Mouse", "protein_name": "MORC family CW-type zinc finger protein 3", "length": 942, "firstPublicDate": "2016-01-20", "FUNCTION": "Nuclear matrix protein which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism and plays a role in innate immunity by restricting different viruses through modulation of the IFN response, Mechanistically, possesses a primary antiviral function through a MORC3-regulated element that activates IFNB1, and this function is guarded by a secondary IFN-repressing function, Sumoylated MORC3-NBs associates with PML-NBs and recruits TP53 and SP100, thus regulating TP53 activity (PubMed:17332504), Binds RNA in vitro, Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3, The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"CW-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAQPPTGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVISDHICLTFTDNGNGMTADKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAMVFTKNGETMSVGFLSQTYLEVIKAEHVVVPIVTFNKHRQMINLTESKASLAAILEHSLFSTEQKLLAELNAIMGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDETAGRKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIIIRGQKVKTQLVSKSLAYIERDVYRPKFLTRTVRITFGFNCRNKDHYGIMMYHKNRLIKAYEKVGCQLKANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTILALGEKLNDYWNEMKVKKNAEYPVNLPVEDIQKRPDQTWVQCDACLKWRKLPDGIDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTSKERFRIRQPEILPRILPQINPELLYQTSVSSQSFSPVKESVPRPHLSEVTSPFAARIINLNLASPASEPENSSMKRKLGVHSSILNAKTRRLSNPPVENSSYKNDDDEDVIILEENSTPKPAVDLEVKSDIEVKSEQSHTEQSGIHVDLVSSPKPCVQASSTSTSTSRSDPGITVSTQTDAPGLTVKKEESMEEDMGVRNGTATLSCVGTEAKVQETSAESVDATSHQLQELRSELLVVTQERDDYKRQCQMFTDQIQVLQQRLLEMNDKCVKKEKCHQSTETDAVFLLDSVNGQAESLDHLGSQYQQALQEIERLKRQCSALQQVKSECSQASCTESKSEVDEMAVQLDDVFRQLDKCTIERDQYKNEVQLLEIEKSHIHSQCEELQTEVEQLKSTGQQAAADGSTASNAEEPVSYVDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST", "length": 942, "molWeight": 106522, "crc64": "29EFFF22B7B24C94", "md5": "B758AE512ACB17F1D4B7877BB0CB140F"}}
{"primaryAccession": "G3HIK4", "text": "This is Cholesteryl ester transfer protein protein, from Chinese hamster, contains 492 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "G3HIK4", "organism_name": "Chinese hamster", "protein_name": "Cholesteryl ester transfer protein", "length": 492, "firstPublicDate": "2014-11-26", "FUNCTION": "Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles, Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:24293641), Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLAVTLLSLALLGSTCACSTSTSYEAGIVCRITKAALLVLNQETAKVIQTAFQRASYPDIKGERSMMLLGRVTYGLHNIQISHLSIASSQVELVEAKSVDVSIQNASVIFKGTLNYGYKGAWGLNIEQSVDFEIESAIDLQINTKLTCDSGHVRTDAPDCSISFHKLLLHLQGEREPGWTKQLFTNIISFTLKMVLKGQVCKEINVISNIMADFVQTRAANIISDRDIEVDISLTRSPIITATYLESHHKGHFIYKNISEVLPLPAFSPTLLGDTRMLYFWFSEQVLDSLAKAAFQDGRLQLNLAETELKVVLETWHFNPNQEIIPEVITGFPSPGQVTVHCPRRPTISCQNKGVVVSSPVVMEFLFPHKDGQDSVTHTFEEDIVATIQASYSKKKLFLSLVDFQIKPKTTSNMAESSESIQNFLQLMITTVGIPEIMSRLEVALTTLMNSKGLDLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLN", "length": 492, "molWeight": 54737, "crc64": "5CF8DFC79ED4FAEA", "md5": "24C3FE76B03DC1252A46EF468D29E636"}}
{"primaryAccession": "G5EFF5", "text": "This is Nuclear hormone receptor family member daf-12 protein, from Caenorhabditis elegans, contains 753 amino acids, has 2 NR C4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [118, 138], "description": "NR C4-type", "keyword_description": "Zinc finger", "textural_description": "NR C4-type Zinc finger"}, {"location": [154, 173], "description": "NR C4-type", "keyword_description": "Zinc finger", "textural_description": "NR C4-type Zinc finger"}], "meta_data": {"primaryAccession": "G5EFF5", "organism_name": "Caenorhabditis elegans", "protein_name": "Nuclear hormone receptor family member daf-12", "length": 753, "firstPublicDate": "2015-10-14", "FUNCTION": "Nuclear receptor which binds directly to response elements in target gene promoters (PubMed:9477318, PubMed:10859169, PubMed:15314028, PubMed:15489294, PubMed:15383841, PubMed:15611047, PubMed:16626392, PubMed:19828440, PubMed:21814518), Activity is modulated by binding of steroid hormone ligands that include dafachronic acids (PubMed:16529801), Regulates expression of genes involved in postembryonic development and the dauer diapause, in response to environmental cues (PubMed:9477318, PubMed:10859169, PubMed:15489294, PubMed:15383841, PubMed:16626392, PubMed:19828440, PubMed:21814518), Inhibits the expression of let-7 family members when bound to corepressor din-1s which is an isoform of din-1 (PubMed:19828440), Plays a role in controlling the timing of seam cell development during the larval stages (PubMed:21471153), Has a role in the immune response to bacterial infection, via regulation of let-7 miRNAs (PubMed:23990780), Controls expression of genes that promote the aerobic catabolism of fatty acids for reproductive growth (PubMed:25774872), May be involved in thermotolerance (PubMed:24957743)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the nuclear hormone receptor family", "domain_description": {"NR C4-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQMSTPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRVCGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFTVGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYPPQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLTMMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLMNEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIPGNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAMIPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQMQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGVTRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAVYLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALGLLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK", "length": 753, "molWeight": 84199, "crc64": "BD166E3A0ED95D08", "md5": "1341751AF04EEE021E37EC3D9A61185E"}}
{"primaryAccession": "I0IUP3", "text": "This is DNA helicase MCM8 protein, from Chicken, contains 830 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "I0IUP3", "organism_name": "Chicken", "protein_name": "DNA helicase MCM8", "length": 830, "firstPublicDate": "2012-10-03", "FUNCTION": "Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis, The MCM8-MCM9 complex probably acts as a hexameric helicase required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCM family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRDLRGRGCPRGRGFQGWRGGWRGGWRGGWRGGWRGRTQKVEWKRAPEPASSRLVQSTLDQFIPYKGWKLYFSEAYADKSPFVQKTQAFEKFFMQRIELYDKDEIERKGSILVDYKELIEDRELTKSIPNISTELRDMPQKILQCMGLAIHQVLTKDLERHAAELQVQEGLPLDGEPIINVPLIHARLYNYEPLTQLKNVRANCYGKYIALRGTVVRVSNIKPLCTKLAFVCGTCGDVQSVPLPDGKYTLPTKCLVPECRGRSFTPDRSSPLTATVDWQSVKVQELMSDDQREAGRIPRTIECELVQDLVDSCVPGDVVTITGVVKVSSTEEGASKNKNDKCVFLLYIEANSVSNSKGQKTKNFEEETFQRSFMEFSLKDLYAVQEIQAEENLFRIIVNSLCPAIYGHEIVKAGLALALFGGCQKFVDDKNRIPVRGDPHVLIVGDPGLGKSQMLQAVCNVAPRGVYVCGNTSTSSGLTVTLSRDGASGDFALEAGALVLGDQGICGIDEFDKMGSQHQALLEAMEQQSISLAKAGIVCSLPARTSIVAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEDHDHLLSEHVMAIRAGKQAVCSSAVVSRTNVQDRSVLEVVSDRPLLERLKISPGENFDAIPHQLLRKYVGYARQYVHPHLSPEAAQVLQEFYLELRKQNQGASSTPITTRQLESLIRLTEARSRLELREKCTKEDAEDVIEIMKYSMLGTYSDEFGKLDFERSQHGSGMSNRSQAKRFVSALSSIAERTYSNLFDLQQLRQVAKELQIRVFDFESFIESLNDQGYLLKKGSRLYQLQTM", "length": 830, "molWeight": 92809, "crc64": "9E0B3F498832B541", "md5": "197CA9C47FBE4B08535FEDBE237C1839"}}
{"primaryAccession": "J3KML8", "text": "This is Golgi-associated olfactory signaling regulator protein, from Mouse, contains 504 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "J3KML8", "organism_name": "Mouse", "protein_name": "Golgi-associated olfactory signaling regulator", "length": 504, "firstPublicDate": "2013-12-11", "FUNCTION": "Required for proper function of the olfactory system, May be involved in establishing the acuity of olfactory sensory signaling", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQPFSPIFFHLLFLLNGLSSRAAPSPGQPVVADLQGMLQPSGMPTGTLENLTRDQPTPGSSASHPPEHSETPPSASPHISTKILRETPSPSPFLSLETPIPDQLTSVAESQGTSQMSPSRATLGKPSETPKPDPTGISPSDSPETPKPNPSNTSPPESPESVYTDPTPTLHHESPEISKRDTPKLSPGEESKIPSPRPTQFLSSKSLETYDPSATRHLNSALEPTTHPDPTESPQSVFLTTHNSNPTVVPQTQFPTSPSQNVTETARTSDLEPSSSLPTQPTTFREEATTPSEPGLSPSPEAPAVTRVATPGLSTSDSPGTKELHVPQNSDPKGPDIPLPSARIAGPPAPLEHPNQVAPAPQRHSRGDTVNTIIVVERVKETGVTLVSRPRGSVGGALCLFFAGTGLLIGIFLLLWCLYRRASRHRSFAHHRLRDSGDEPVLHLDAPKDPLDLYFYAPDAWVPSHIATQPPPSTPPLPPKLPPPPRGPQRLEALSPAALSPNFF", "length": 504, "molWeight": 53786, "crc64": "156177DDBC6C558D", "md5": "9E9CD6F8306D7BDBD331989F4A01FCB2"}}
{"primaryAccession": "K4C9E2", "text": "This is Neoxanthin synthase, chloroplastic protein, from Tomato, contains 498 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "K4C9E2", "organism_name": "Tomato", "protein_name": "Neoxanthin synthase, chloroplastic", "length": 498, "firstPublicDate": "2016-04-13", "FUNCTION": "Involved in the synthesis of neoxanthin, the last product of carotenoid synthesis and a precursor of abscisic acid (PubMed:11029576), Involved in the beta-carotene biosynthesis (PubMed:10995464)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the lycopene cyclase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "METLLKPFPSLLLSSPTPYRSIVQQNPSFLSPTTKKKSRKCLLRNKSSKLFCSFLDLAPTSKPESLDVNISWVDPNSNRAQFDVIIIGAGPAGLRLAEQVSKYGIKVCCVDPSPLSMWPNNYGVWVDEFENLGLEDCLDHKWPMTCVHINDNKTKYLGRPYGRVSRKKLKLKLLNSCVENRVKFYKAKVWKVEHEEFESSIVCDDGKKIRGSLVVDASGFASDFIEYDRPRNHGYQIAHGVLVEVDNHPFDLDKMVLMDWRDSHLGNEPYLRVNNAKEPTFLYAMPFDRDLVFLEETSLVSRPVLSYMEVKRRMVARLRHLGIKVKSVIEEEKCVIPMGGPLPRIPQNVMAIGGNSGIVHPSTGYMVARSMALAPVLAEAIVEGLGSTRMIRGSQLYHRVWNGLWPLDRRCVRECYSFGMETLLKLDLKGTRRLFDAFFDLDPKYWQGFLSSRLSVKELGLLSLCLFGHGSNMTRLDIVTKCPLPLVRLIGNLAIESL", "length": 498, "molWeight": 56458, "crc64": "1C4D3B5DAD9B6B40", "md5": "D48A49576104AF57817E0CA2A5896280"}}
{"primaryAccession": "K7WDL7", "text": "This is (S)-8-oxocitronellyl enol synthase protein, from Madagascar periwinkle, contains 388 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "K7WDL7", "organism_name": "Madagascar periwinkle", "protein_name": "(S)-8-oxocitronellyl enol synthase", "length": 388, "firstPublicDate": "2013-05-29", "FUNCTION": "Iridoid synthase that catalyzes the first step in generation of the iridoid ring scaffold using the linear monoterpene (6E)-8-oxogeranial as substrate, Iridoids comprise a large family of distinctive bicyclic monoterpenes that possess a wide range of pharmacological activities, including anticancer, anti-inflammatory, antifungal and antibacterial activities", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the short-chain dehydrogenases/reductases (SDR) family, Highly divergent", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSWWWKRSIGAGKNLPNQNKENGVCKSYKSVALVVGVTGIVGSSLAEVLKLPDTPGGPWKVYGVARRPCPVWLAKKPVEYIQCDVSDNQETISKLSPLKDITHIFYVSWIGSEDCQTNATMFKNILNSVIPNASNLQHVCLQTGIKHYFGIFEEGSKVVPHDSPFTEDLPRLNVPNFYHDLEDILYEETGKNNLTWSVHRPALVFGFSPCSMMNIVSTLCVYATICKHENKALVYPGSKNSWNCYADAVDADLVAEHEIWAAVDPKAKNQVLNCNNGDVFKWKHIWKKLAEEFGIEMVGYVEGKEQVSLAELMKDKDQVWDEIVKKNNLVPTKLKEIAAFWFADIAFCSENLISSMNKSKELGFLGFRNSMKSFVSCIDKMRDYRFIP", "length": 388, "molWeight": 43850, "crc64": "906C11AD93A04E76", "md5": "5A7BCC8CF138129BCF47CD07CD8BF5A3"}}
{"primaryAccession": "O00463", "text": "This is TNF receptor-associated factor 5 protein, from Human, contains 557 amino acids, has 1 RING-type Zinc finger, has 2 TRAF-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [45, 85], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [127, 181], "description": "TRAF-type", "keyword_description": "Zinc finger", "textural_description": "TRAF-type Zinc finger"}, {"location": [182, 239], "description": "TRAF-type", "keyword_description": "Zinc finger", "textural_description": "TRAF-type Zinc finger"}], "meta_data": {"primaryAccession": "O00463", "organism_name": "Human", "protein_name": "TNF receptor-associated factor 5", "length": 557, "firstPublicDate": "2003-05-09", "FUNCTION": "Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases, Mediates activation of NF-kappa-B and probably JNK, Seems to be involved in apoptosis, Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TNF receptor-associated factor family, A subfamily", "domain_description": {"RING-type Zinc finger": 1, "TRAF-type Zinc finger": 2}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAYSEEHKGMPCGFIRQNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDLTDLEDL", "length": 557, "molWeight": 64406, "crc64": "86EB3724CE111176", "md5": "12751AF68BBF7E02FF4A86469EB763F2"}}
{"primaryAccession": "O00623", "text": "This is Peroxisome assembly protein 12 protein, from Human, contains 359 amino acids, has 1 RING-type; degenerate Zinc finger, is membrane-bound, locates in Peroxisome.", "functionDomainRange": [{"location": [304, 343], "description": "RING-type; degenerate", "keyword_description": "Zinc finger", "textural_description": "RING-type; degenerate Zinc finger"}], "meta_data": {"primaryAccession": "O00623", "organism_name": "Human", "protein_name": "Peroxisome assembly protein 12", "length": 359, "firstPublicDate": "1998-07-15", "FUNCTION": "Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (PubMed:9354782, PubMed:9632816, PubMed:24662292), The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity), PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10 (PubMed:24662292), When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation (By similarity)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the pex2/pex10/pex12 family", "domain_description": {"RING-type; degenerate Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAEHGAHFTAASVADDQPSIFEVVAQDSLMTAVRPALQHVVKVLAESNPTHYGFLWRWFDEIFTLLDLLLQQHYLSRTSASFSENFYGLKRIVMGDTHKSQRLASAGLPKQQLWKSIMFLVLLPYLKVKLEKLVSSLREEDEYSIHPPSSRWKRFYRAFLAAYPFVNMAWEGWFLVQQLRYILGKAQHHSPLLRLAGVQLGRLTVQDIQALEHKPAKASMMQQPARSVSEKINSALKKAVGGVALSLSTGLSVGVFFLQFLDWWYSSENQETIKSLTALPTPPPPVHLDYNSDSPLLPKMKTVCPLCRKTRVNDTVLATSGYVFCYRCVFHYVRSHQACPITGYPTEVQHLIKLYSPEN", "length": 359, "molWeight": 40797, "crc64": "1AF0BE6416422109", "md5": "61CA2B4C3AA38EA2ADD81DFD93406EA9"}}
{"primaryAccession": "O00841", "text": "This is Putative transcriptional regulator cudA protein, from Social amoeba, contains 802 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O00841", "organism_name": "Social amoeba", "protein_name": "Putative transcriptional regulator cudA", "length": 802, "firstPublicDate": "2004-05-10", "FUNCTION": "Essential for normal culmination, May function as a transcriptional regulator", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNQSQNFHNIDLGHYGAQGSNQSFNNNNNGNNGMMMNQQQMQQHVVPHLHHLQQQQQQPQQQQLRNVPDYSNSPNGTTNGSTMSPNCINTNNNNNNNNNNNNNSNNNNNNNNNASNNLTSNKSSSTNTPQIGQLQASPANLTNSPSAISSPITISNNSSLNSPSTTSSPNLLLNGTSNKRIMISQQTCLVEEKFSKNGVQKNVHVVVKNNPFLLTLSLLDSSLNFHQLTPEVQLVYDSESLKEVDSATVKPLEYKTRANEEGDQLTIELRIKVLSSQLEDMLFRAKVKIVDPRTRKETHGLSVITHPIRVVSKPDQVKKKAKKRKRAPTDSLMDTLNRIEHQQKEQQRLLKKLCYHDKENNIIQLIQQQQQQQQLLNNVTNNINNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTSTTTTTTTTTSSCNNNNNNNNENNEHIVKIENTECNNNNNNIINNTENDENINKPILNSKDEFQSAFKEFIGAFKQLQCLDPDGADGAFKINTCANDAQTMCEILEMVKVELKKDENFKDKCGGSSGGACGENNPDNPCSCKVCPYKQKVDHINQSYETYFNMFNPSNSNSVVPQQSQQLQQQQIQQQQQSQQQVQQQQQQQMQQQPQQQQQQPQQQQQNQQQGQQPQQQQQQGQLDYTTYIDPQLQMQQQLQMQQAAQQQYMQQTMDQQQQQQYYMQQYHLQQQQQQQQAQRYLMQQQYMQQQAQQQQQQHQQVAIQQQQQQNQQQNQQQNQQQQNQSPQNQQSLDFQNANNFIDFNSGLGFMNFPNINFGDMGFSAV", "length": 802, "molWeight": 91743, "crc64": "62140CA14005533F", "md5": "2A00006E85188B6730F8400BA62462BC"}}
{"primaryAccession": "O04147", "text": "This is Cyclic phosphodiesterase protein, from Mouse-ear cress, contains 181 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O04147", "organism_name": "Mouse-ear cress", "protein_name": "Cyclic phosphodiesterase", "length": 181, "firstPublicDate": "2004-08-16", "FUNCTION": "Hydrolyzes ADP-ribose 1'',2''-cyclic phosphate (Appr>1) that is produced during tRNA splicing into ADP-ribose 1''-phosphate (Appr-1''p) (PubMed:9148938), Acts also on nucleoside 2',3'-cyclic phosphates (PubMed:9148938)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the 2H phosphoesterase superfamily, CPD1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEEVKKDVYSVWALPDEESEPRFKKLMEALRSEFTGPRFVPHVTVAVSAYLTADEAKKMFESACDGLKAYTATVDRVSTGTFFFQCVFLLLQTTPEVMEAGEHCKNHFNCSTTTPYMPHLSLLYAELTEEEKKNAQEKAYTLDSSLDGLSFRLNRLALCKTDTEDKTLETWETVAVCNLNP", "length": 181, "molWeight": 20514, "crc64": "5FFDFC57213BEE34", "md5": "2879CAA9D6E9BE4E546B94DA8B6A2F74"}}
{"primaryAccession": "O04196", "text": "This is Isoamylase 1, chloroplastic protein, from Mouse-ear cress, contains 783 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O04196", "organism_name": "Mouse-ear cress", "protein_name": "Isoamylase 1, chloroplastic", "length": 783, "firstPublicDate": "2009-07-07", "FUNCTION": "Involved in the trimming of pre-amylopectin chains, Accelerates the crystallization of nascent amylopectin molecules during starch synthesis, ISA1 and ISA2 work exclusively together as a multimeric holoenzyme, ISA1-ISA2 removes preferentially branches that are very close to other branches, Promotes negative gravitropic responses in shoots by facilitating starch granules (statoliths) formation in hypocotyls (PubMed:34367195)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the glycosyl hydrolase 13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDAIKCSSSFLHHTKLNTLFSNHTFPKISAPNFKPLFRPISISAKDRRSNEAENIAVVEKPLKSDRFFISDGLPSPFGPTVRDDGVNFSVYSTNSVSATICLISLSDLRQNKVTEEIQLDPSRNRTGHVWHVFLRGDFKDMLYGYRFDGKFSPEEGHYYDSSNILLDPYAKAIISRDEFGVLGPDDNCWPQMACMVPTREEEFDWEGDMHLKLPQKDLVIYEMHVRGFTRHESSKIEFPGTYQGVAEKLDHLKELGINCIELMPCHEFNELEYYSYNTILGDHRVNFWGYSTIGFFSPMIRYASASSNNFAGRAINEFKILVKEAHKRGIEVIMDVVLNHTAEGNEKGPIFSFRGVDNSVYYMLAPKGEFYNYSGCGNTFNCNHPVVRQFILDCLRYWVTEMHVDGFRFDLGSIMSRSSSLWDAANVYGADVEGDLLTTGTPISCPPVIDMISNDPILRGVKLIAEAWDAGGLYQVGMFPHWGIWSEWNGKFRDVVRQFIKGTDGFSGAFAECLCGSPNLYQGGRKPWHSINFICAHDGFTLADLVTYNNKNNLANGEENNDGENHNYSWNCGEEGDFASISVKRLRKRQMRNFFVSLMVSQGVPMIYMGDEYGHTKGGNNNTYCHDNYMNYFRWDKKEEAHSDFFRFCRILIKFRDECESLGLNDFPTAKRLQWHGLAPEIPNWSETSRFVAFSLVDSVKKEIYVAFNTSHLATLVSLPNRPGYRWEPFVDTSKPSPYDCITPDLPERETAMKQYRHFLDANVYPMLSYSSIILLLSPIKDP", "length": 783, "molWeight": 89481, "crc64": "638A6F9088CDB896", "md5": "ED774D756A77980210D2D32E20DDD5AC"}}
{"primaryAccession": "O04202", "text": "This is Eukaryotic translation initiation factor 3 subunit F protein, from Mouse-ear cress, contains 293 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O04202", "organism_name": "Mouse-ear cress", "protein_name": "Eukaryotic translation initiation factor 3 subunit F", "length": 293, "firstPublicDate": "2002-09-19", "FUNCTION": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome, The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation (Potential), Involved in cell growth and differentiation, especially during embryogenesis and male gametophyte germination (PubMed:20444226), Regulates sensitivity to sugars (e,g, sucrose) (PubMed:20444226)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eIF-3 subunit F family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAATSEHTILQFVSPSSTASATTSVLTARIHPLVIFNVCDCFVRRPDSAERVIGTLLGSILPDGTVDIRNSYAVPHNESSDQVAVDIDYHHNMLASHLKVNSKETIVGWYSTGAGVNGGSSLIHDFYAREVPNPIHLTVDTGFTNGEGTIKAFVSSNLSLGDRQLVAHFQEIPVDLRMVDAERVGFDVLKATSVDKLPNDLEGMELTMERLLTLINDVYKYVDSVVGGQIAPDNNIGRFIADAVASLPKLPPQVFDNLVNDSLQDQLLLLYLSSITRTQLSLAEKLNTAAQML", "length": 293, "molWeight": 31862, "crc64": "4742CF7E8F6F47C7", "md5": "1BA7E529637585F84E527E4CCF468884"}}
{"primaryAccession": "O04479", "text": "This is Protein ASYMMETRIC LEAVES 2 protein, from Mouse-ear cress, contains 199 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O04479", "organism_name": "Mouse-ear cress", "protein_name": "Protein ASYMMETRIC LEAVES 2", "length": 199, "firstPublicDate": "2003-03-28", "FUNCTION": "Negative regulator of cell proliferation in the adaxial side of leaves, Regulates the formation of a symmetric lamina and the establishment of venation, Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV, Interacts directly with ASYMMETRIC LEAVES 1 (AS1) to repress the knox homeobox genes KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3, KAN2 and YAB5, May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis (PubMed:11311158, PubMed:12787254, PubMed:12874130, PubMed:14508003, PubMed:16006579, PubMed:16699177, PubMed:17395603, PubMed:17559509), Required for the binding of AS1 to the KNOX genes (PubMed:23271976), Involved in leaf polarity establishment by functioning cooperatively with RH10 or RID2 to repress abaxial genes ARF3, ARF4, KAN1, KAN2, YAB1 and YAB5, and the knox homeobox genes KNAT1, KNAT2, KNAT6, and STM to promote adaxial development in leaf primordia at shoot apical meristems at high temperatures (PubMed:27334696)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the LOB domain-containing protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASSSTNSPCAACKFLRRKCQPECVFAPYFPPDQPQKFANVHKVFGASNVTKLLNELHPSQREDAVNSLAYEADMRLRDPVYGCVGVISLLQHQLRQLQIDLSCAKSELSKYQSLGILAATHQSLGINLLAGAADGTATAVRDHYHHHQFFPREQMFGGLDVPAGNNYDGGILAIGQITQFQQPRAAAGDDGRRTVDPS", "length": 199, "molWeight": 21710, "crc64": "CF75859362F36686", "md5": "DFBED080454EF1137C7C7BEDFD2CF24C"}}
{"primaryAccession": "O08722", "text": "This is Netrin receptor UNC5B protein, from Rat, contains 945 amino acids, has 1 Ig-like Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [48, 145], "description": "Ig-like", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like Immunoglobulin domain"}, {"location": [153, 242], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "O08722", "organism_name": "Rat", "protein_name": "Netrin receptor UNC5B", "length": 945, "firstPublicDate": "2004-10-11", "FUNCTION": "Receptor for netrin required for axon guidance, Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding, Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion (PubMed:10399920, PubMed:9126742), Functions as netrin receptor that negatively regulates vascular branching during angiogenesis, Mediates retraction of tip cell filopodia on endothelial growth cones in response to netrin (By similarity), It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:11387206), Mediates apoptosis by activating DAPK1 (PubMed:18582460), In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity (PubMed:15729359)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the unc-5 family", "domain_description": {"Ig-like Immunoglobulin domain": 1, "Ig-like C2-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRARSGARGALLLALLLCWDPTPSLAGIDSGGQALPDSFPSAPAEQLPHFLLEPEDAYIVKNKPVELHCRAFPATQIYFKCNGEWVSQKGHVTQESLDEATGLRIREVQIEVSRQQVEELFGLEDYWCQCVAWSSSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQACQKTACTTVCPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCVLNQRTLNDPKSRPLEPSGDVALYAGLVVAVFVVLAVLMAVGVIVYRRNCRDFDTDITDSSAALTGGFHPVNFKTARPSNPQLLHPSAPPDLTASAGIYRGPVYALQDSADKIPMTNSPLLDPLPSLKIKVYDSSTIGSGAGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLTIPGTGVSLLVPNGAIPQGKFYDLYLRINKTESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIAGDWIFQLKTQAHQGHWEEVVTLDEETLNTPCYCQLEAKSCHILLDQLGTYVFTGESYSRSAVKRLQLAIFAPALCTSLEYSLRVYCLEDTPAALKEVLELERTLGGYLVEEPKTLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQKALHCTFTLERHSLASTEFTCKVCVRQVEGEGQIFQLHTTLAETPAGSLDALCSAPGNAATTQLGPYAFKIPLSIRQKICNSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMTTDGDC", "length": 945, "molWeight": 103521, "crc64": "6E9C2A262E560B9B", "md5": "D535FE830A6E3080FCB4327610FE3505"}}
{"primaryAccession": "O08750", "text": "This is Nuclear factor interleukin-3-regulated protein protein, from Mouse, contains 462 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O08750", "organism_name": "Mouse", "protein_name": "Nuclear factor interleukin-3-regulated protein", "length": 462, "firstPublicDate": "2007-06-26", "FUNCTION": "Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters, Represses transcription from promoters with activating transcription factor (ATF) sites (By similarity), Represses promoter activity in osteoblasts, Represses transcriptional activity of PER1, Represses transcriptional activity of PER2 via the B-site on the promoter, Activates transcription from the interleukin-3 promoter in T-cells (By similarity), Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF), Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock, Protects pro-B cells from programmed cell death, Represses the transcription of CYP2A5 (PubMed:30555544), Positively regulates the expression and activity of CES2 by antagonizing the repressive action of NR1D1 on CES2 (PubMed:29653076), Required for the development of natural killer cell precursors (PubMed:32190943)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family, NFIL3 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQLRKMQTIKKEPAPLDPTSSSDKMLLLNSALAEVAEDLASGEDLLLNEGSMGKNKSSACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISSTAYAQEIQKLSNSTAVYFQDYQTSKAAVSSFVDEHEPAMVAGSCISVIKHSPQSSLSDVSEVSSVEHTQESPAQGGCRSPENKFPVIKQEPVELESFAREAREERGTYSTSIYQSYMGSSFSTYSHSPPLLQVHGSTSNSPRTSEADEGVVGKSSDGEDEQQVPKGPIHSPVELQRVHATVVKVPEVNPSALPHKLRIKAKAMQVKVEALDSEFEGMQKLSSPADAIAKRHFDLEKHGTSGMAHSSLPPFSVQVTNIQDWSLKSEHWHHKELSSKTQSSFKTGVVEVKDGGYKVSEAENLYLKQGIANLSAEVVSLKRFIATQPISASDSR", "length": 462, "molWeight": 50943, "crc64": "DC711EB4CAC0112E", "md5": "F9F33FD2A41AA722BE27972229E9811C"}}
{"primaryAccession": "O08858", "text": "This is Somatostatin receptor type 5 protein, from Mouse, contains 362 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O08858", "organism_name": "Mouse", "protein_name": "Somatostatin receptor type 5", "length": 362, "firstPublicDate": "1997-11-01", "FUNCTION": "Receptor for somatostatin-28, The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, Increases cell growth inhibition activity of SSTR2 following heterodimerization", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEPLSLTSTPSWNASAASSSSHNWSLVDPVSPMGARAVLVPVLYLLVCTVGLGGNTLVIYVVLRYAKMKTVTNVYILNLAVADVLFMLGLPFLATQNAVSYWPFGSFLCRLVMTLDGINQFTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKLASAAVWVFSLLMSLPLLVFADVQEGWGTCNLSWPEPVGLWGAAFITYTSVLGFFGPLLVICLCYLLIVVKVKAAGMRVGSSRRRRSERKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKALCLRRGYGVEDADAIEPRPDKSGRPQTTLPTRSCEANGLMQTSRL", "length": 362, "molWeight": 40008, "crc64": "C069149B8A8141C4", "md5": "73022CAB58396941117B225D4AE1BDB7"}}
{"primaryAccession": "O13684", "text": "This is Monopolin complex subunit pcs1 protein, from Fission yeast, contains 261 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13684", "organism_name": "Fission yeast", "protein_name": "Monopolin complex subunit pcs1", "length": 261, "firstPublicDate": "1998-07-15", "FUNCTION": "The monopolin-like pcs1/mde4 complex is essential for accurate chromosome segregation during mitosis and meiosis II, May clamp together microtubule binding sites on the same kinetochore, preventing merotelic attachment of microtubules, In contrast to its S,cerevisiae ortholog CSM1, is not required ofr mono-orientation during meiosis I", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRKNNMQTSKDSELKEQAKGKSSKLIHKLPKQRTRISQGQMHSTQDFVNNEDQDAYSVRENENELHINNSGMSELNKKLQLPNVELSTLSHTQEQEFNELNKLIRKINELQEFYLLEDLAKPVTNAGADADDTIVKDLKKELENEKKANHSLKNELLKTREQIKNYSKINILIKELFGLEVADCIEDEDGYRFNCKNTGRRGTLEYQLLLDDQNFTFTPRLNVQTDEELMKHLPDYLLEEIIFTKEQGKLFSARLMKALQD", "length": 261, "molWeight": 30418, "crc64": "788A079D2920CE35", "md5": "D6D08710B5D4C537630A0D5E134CB2F8"}}
{"primaryAccession": "O13716", "text": "This is Glucan endo-1,3-alpha-glucosidase agn1 protein, from Fission yeast, contains 424 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13716", "organism_name": "Fission yeast", "protein_name": "Glucan endo-1,3-alpha-glucosidase agn1", "length": 424, "firstPublicDate": "1998-07-15", "FUNCTION": "Has a role in cell separation where it is required for the degradation of the cell wall material surrounding the septum (the septum edging) which must be hydrolyzed before full separation of the daughter cells can occur, Hydrolyzes 1,3-alpha-glucan predominantly into pentasaccharides", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 71 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLVLFLVLLFSALINLTNADKMVVAHFIVGNTYPYTVSNWEEDIQDAIAVGIDGFALNMGSDAWQVERIEDAYDAAASVSSDFKLFISFDMSIISADADFIEGVVRRFADKPNQLYYDGKVFVSTFAGETDTFGYSDVSTGWDSAVKEPLASAGYPIYFVPSWTSLGQGALEESVADGFLSWNAWPTTDADMNDNDDIGYQNLANSLGKLYVAPVSPWFYTHLSYKNWAYKSDWLIIDRWNEMLSVQPDMIEVLTWNDYGESHYIGNIQGALPAGSEGYVDGFDHTAWRYLMSPYISAYKLGLSEPYINFESLFYWYRPTPKSATATADSLSYPSGGDYMEDEIFVLVYLLQSAEVTVTCGSTTQTFSGVPGVNQFTIPMETNASPSFTVARQGGTLASGTGPEIVDSLSIYNFNAYTGVLYF", "length": 424, "molWeight": 46974, "crc64": "2D680FDB8C56AEBF", "md5": "C0C776E870280247C34C8CB69CBB7E41"}}
{"primaryAccession": "O13816", "text": "This is Cohesin subunit psc3 protein, from Fission yeast, contains 962 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13816", "organism_name": "Fission yeast", "protein_name": "Cohesin subunit psc3", "length": 962, "firstPublicDate": "1998-07-15", "FUNCTION": "Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication, The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped, At anaphase, the rad21 subunit of the cohesin complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate, The cohesin complex may also play a role in spindle pole assembly during mitosis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SCC3 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSESVTTGSDDDGGDRESSPVMLSQSFDPMSSSSNSSSEENSDDDYEKTISSKKRHPRPNSKGVNVKRSRRNAIVEEDPQEEIFNNLFAFLLDQKVDTMDIAVSWFADYAKDNQSALANLINFILKCCGCNRAINVFDVQDQDSASATLSQIQLSVERTSTRDYPLNSKNLKFRNFRKRLTGLLSNFVSQLSIRNYLYNSTVFEDIMSWVVAMSSSTMRPIRHTATVFCLNIMTFLCEKSKELLNEHAIATKQLEKEEKRSRVNRNRINELNNSLGEIVKQQDTLTTYLNDYFDSVFVHRYRDVEPKIRVDCLQELGVWINTVPSIFFSGSYLRYLGWMLSDINTTVRLTVVKVLRKFFETDSFIGGLRHFSSRFKERILEMSCVDADIGVRVASIRLCNAMRTCGFLENSEILKVLKLILDINPRVQREAVLFLCKVVDESVNEKIDLWGEEDYILKAFSQTSLTTFSVHWIKFSQMCKLLEEVRLSYQSSFDYDTLLRIFQKNGNFITPITQALLNACEIDSIYQSWEDISNFVLFDNYTSTLKDPIDSILSFCKLNDFQESILLQLLSASIQTVCNNNFITPKTVHNKQAAETTNDQNKDKDLLYLNLLPYINSITERNSASPTLLHDSLRLLFSMDLTEMTDPQLSRHFELLINNLKKFFLTNNDLQIIQGCTILFLRLDSIPALKEDLKLLVTDICDQTVTEFLKNFGSFNIQDAVITKDEFVIFEACLTRIEGCTSLKDFSDYPEFDIIYERLVSLLSRVPNSYEDTLKFSAINTLQSLLFWFFLRKDNPADEEKKKDDETKVFNCLINIMNNDSSKILQLQAARTFLETVIMKEGVKASHYNDDNRVSEEHNFLKPQFLDALLKILEGWLYTYAKVGQFPFKRLTQASSPHTQISLDKNPLNRRLLEHVCCDLTSKLLIVVSLSNTITPEFSQQFCELRGHYGPKLSAIVDEFLN", "length": 962, "molWeight": 110652, "crc64": "F45C2C2A2E0443CC", "md5": "CB9896E6048C43918134FBE6DC6CC262"}}
{"primaryAccession": "O13881", "text": "This is Cryptic loci regulator 2 protein, from Fission yeast, contains 537 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13881", "organism_name": "Fission yeast", "protein_name": "Cryptic loci regulator 2", "length": 537, "firstPublicDate": "1998-07-15", "FUNCTION": "Required for deacetylation in the mating-type region and the centromere, Acts upstream of the histone deacetylases to promote transcriptional silencing, Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing repressor complex (SHREC)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPAITCVWSDGRSDTWPNVNGHSRTRSVPSLKPLPHQDSKNLLYRQICGRLLAQHVFGGAGSTQPILNQLCKRLSTGNPNNTNASTVVTAPEKNVVSARHVRPNPKSSKDTLEKQPKYSSQIYLTDSFENYYLASLPTNYQLYQRDSNRENGNGKREFWLYGHPSGRPFRSVNDFLHHLYWLISDLTRNESTCCCVLCSGNMTRVRKNLQKENERMFHECKDDTYTWPSSYRLGEVVWIDINNELIPAIIVARNLINYESNQMDAVKLISDTFVEPYQYHCKQLGNSRYYFDMAAADIEPWSRHPLDLQKQEHLVAHSICQTWNLFGIFQPLEGIDMEEPKFHDENYSIPLTVLPTFGGESNSLDDHFYGIFRGAEKLWINDLCVISTSSLPSVLQKTSFMYISDIYVNEDDIVCFQGSLWTQIDKNALDYNDSADNIDEHKDDLKELPRRLQMVSKLSNTYFRCLHDKSVEYVCPFADVLGRWYEPWFVKGDLNYTSEVKERTSSRLSAVGSENWVDDDFYEYLLSEIDMVSAVVM", "length": 537, "molWeight": 61971, "crc64": "B4EF6EA63FAF75CA", "md5": "5D2B49E1DA966C04185BA01D3A25D161"}}
{"primaryAccession": "O13936", "text": "This is Transcription elongation factor spt5 protein, from Fission yeast, contains 990 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13936", "organism_name": "Fission yeast", "protein_name": "Transcription elongation factor spt5", "length": 990, "firstPublicDate": "2006-05-30", "FUNCTION": "The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing, This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SPT5 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDTNSPKSIDKDANSTEVDAAEQDAASVKINSTRASPNGSDLLNDDSEAAKITTNEKQSSPVDSHNESPNDTTINKGEDGNENEVDNVNNNDKKEDEDNVEENEEEADANEEEEEDEEDDEEDEEDEDESGGGRRKRARHDRRNQFLDIEAEVDEDEEELEDEEDEIGREDGFIEEEVGADYVGDDRRHRELDRQRQELQSVDAERLAEEYREKYGRSQTVVGDTSNVPQRLLLPSVNDPNIWAVRCKIGKEKDIVFTIMRKAMDLQYTSSPLEIISAFQRDSLVGYIYVEARKQSHVLDALNGVLNVYTNNMILVPIKEMPDLLKVQKQVVELLPGAYVRIRRGKYAGDLAQVDNLSENGLTARVRIVPRIDYSDGLKRKNSATRPQARLFNESEAFKSNPSKFSKRGPRLFLFNNEEFEDGFLVKDIRISSLITEGVNPTLDEVSKFNPNNEDLDLSSLALSVKGGHAEFQPGDHVEVYVGEQTGVSGVVENVRGSVITMVSSDGLRLDVPSRGLRKRFRHGDYVKVIAGKYKDDTGMVVRISKDEVTFLSDTLMTELTVFSRDLGEASSAQAVNSAYELHDLVQLDVNTVACIFSVDRDTYKVIDQNGGVRTVLASQITMRHSNRRGVATDRNGAEIRIGDKVKEVGGEGKQGTILHIYRAFVFLHNRDIAENNGVFSARSRNVATIAAKGARISADLTKMNPALSNGPALPPVANLKRTIGRDKAIGATVRIRRGPMKGLLGVIKDTTDANARVELHTGNKMVTIPKENLLYTTKTGELISYTEFIERSRGIRPGSISTADGPNVPNWAQGARTPAVANGSRTPAWNTGSRTPAWNSGSKTPAWNSGSRTPAWNSGNKTPAWNAGSRTPAWNSGNKTPAWNVGNKTPAWNSGAKTPAWNAGNKTPSWNNGTKTPAWNANQTPMVANGTNTSWGQTPAYGGFSETNWDTEDNSKPYTAPTPGAWAAPTPGGWDDEEGDSPKYVPPSP", "length": 990, "molWeight": 109014, "crc64": "6FF52652D1C8EE89", "md5": "47F10FF4252D872002D469BBA4BDC257"}}
{"primaryAccession": "O13995", "text": "This is Cytochrome P450 regulator dap1 protein, from Fission yeast, contains 166 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13995", "organism_name": "Fission yeast", "protein_name": "Cytochrome P450 regulator dap1", "length": 166, "firstPublicDate": "2000-05-30", "FUNCTION": "Required for sterol biosynthesis, Functions as a positive regulator of cytochrome P450 enzymes erg5 and erg11, Function requires bound heme", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the cytochrome b5 family, MAPR subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASTQVVFIVTLFLYLLITRWRRKNEKSFIASEEPKQPEWRDYTPAELKEYNGSKNSLVFLAIKGTVYNVTMGSKFYGPQGPYSAFAGHDASRGLAKNSFDDEFIPDSDAEELDDCSDLNDEERQALNDWKAFFDQKYQAVGRLISPREARAAATISETEEKVAHN", "length": 166, "molWeight": 18874, "crc64": "940BE5977503F735", "md5": "D58BB8C5423C5AF48D44621E67CFC91C"}}
{"primaryAccession": "O14023", "text": "This is Elongator complex protein 3 protein, from Fission yeast, contains 544 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14023", "organism_name": "Fission yeast", "protein_name": "Elongator complex protein 3", "length": 544, "firstPublicDate": "2007-11-13", "FUNCTION": "Catalytic tRNA acetyltransferase subunit of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:22768388), In the elongator complex, acts as a tRNA uridine(34) acetyltransferase, which mediates formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ELP3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSTSSLAFLKAKACAEIVAELIASENQNKVINLNALKMRISKKHQLSESPRLTDIIAAIPPDAYLKESLMRKLRAKPVRTASGIAVVAVMCKPHRCPHIAMTGNVCVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYEQARGRVEQLRSLGHTVDKVEYIIMGGTFMSLPESYRHTFIANLHNALSGATTEDLDEAVKFSEQSETKCVGITIETRPDYCLDQHLDEMLRYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCETFQLAKDTGYKVVTHMMPDLPNVGMERDIFQFQEYFENPAFRTDGLKLYPTLVIRGTGLYELWKTGRYKNYTPNALVDLIARILALVPPWTRIYRIQRDIPMPLVSSGVETGNLRELALNRMRDLGTKCRDIRAREVGMQEVHHKIHPEQVELLRRDYTANGGWETFLSYEDPKQDILIGLLRLRQCSDKTYRPEFTSQPTSLVRELHVYGSAVPVHSRDPKKFQHQGFGTLLLEEAERIAKYEHGSKKISVISGVGVRKYYQKLGYTLDGPYMSKWL", "length": 544, "molWeight": 61850, "crc64": "ACF2CF7C49C6AB5B", "md5": "B7CB88C42AB81C0BBC8B6D94F9C98157"}}
{"primaryAccession": "O14036", "text": "This is Small nuclear ribonucleoprotein Sm D2 protein, from Fission yeast, contains 115 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14036", "organism_name": "Fission yeast", "protein_name": "Small nuclear ribonucleoprotein Sm D2", "length": 115, "firstPublicDate": "2001-01-11", "FUNCTION": "Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the snRNP core protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MADLVDKPRSELSEIELARLEEYEFSAGPLSVLQQAVKNHDQVLINCRNNKKLLARVKAFDRHSNMVLENVKEMWTEKKRTASGKKGKAINKDRFISKMFLRGDGVVLVVRIPSA", "length": 115, "molWeight": 13095, "crc64": "EF39B51D94356C33", "md5": "C1AA85C304F0568E910895A9AB2A48E3"}}
{"primaryAccession": "O14246", "text": "This is Protection of telomeres protein tpz1 protein, from Fission yeast, contains 508 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14246", "organism_name": "Fission yeast", "protein_name": "Protection of telomeres protein tpz1", "length": 508, "firstPublicDate": "2007-09-11", "FUNCTION": "Telomeric DNA-binding protein that is required to protect the 3'-end telomeric overhang and involved in telomere length regulation, recruits poz1 and ccq1 to telomeres, regulating telomere length negatively and positively respectively", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSNCLKHPWLENGLLNLIKNADVLPIRVFKCQPLQIFEYIRYEHPIRCKLSDTEFYIEAEFSSQSISDLNNFTEKRITSLRGGIVTLGNFLIHLIPSQSGIIPWIQVESFNFQGCEGAVFGNPKAITTSALFNALLQSPYLAALANEFNRSIKEGSSYQEASLSQQEKPNDNTSNSRDIKNNIQFHWKNMTSLSIEECIIPKGQQLILEKESEENTTHGIYLEERKMAQGLHNSVSETPEVKQEDNDEDLDAYSWSSSTDSAGEIPSLPTNRKILEKIAEKPPPFESPLEDDETPDQTNEHEANQVNVSQLPLNPRGSGISGRPVESTEQLNSSLTIERSQSIQSTDSKQRVETQSHRRSKIEIFDAQDELFDRSICTTIDDSTGKLLNAEETPIKTGDLHSTSASSVISCTPPAINFTSDICNEQIELEYKRKPIPDYDFMKGLETTLQELYVEHQSKKRRLELFQLTNNHQKNSEACEMCRLGLPHGSFFELLRDWKKIEEFRNKS", "length": 508, "molWeight": 57684, "crc64": "A1A2F59238DACBF7", "md5": "4BC1627A925F857F72D007DB21094979"}}
{"primaryAccession": "O14843", "text": "This is Free fatty acid receptor 3 protein, from Human, contains 346 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14843", "organism_name": "Human", "protein_name": "Free fatty acid receptor 3", "length": 346, "firstPublicDate": "1998-07-15", "FUNCTION": "G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity, In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers, SCFAs serve as a source of energy but also act as signaling molecules, That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins, Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation (PubMed:12711604), Activated by SCFAs and by beta-hydroxybutyrate, a ketone body produced by the liver upon starvation, it inhibits N-type calcium channels and modulates the activity of sympathetic neurons through a signaling cascade involving the beta and gamma subunits of its coupled G protein, phospholipase C and MAP kinases, Thereby, it may regulate energy expenditure through the control of the sympathetic nervous system that controls for instance heart rate, Upon activation by SCFAs accumulating in the intestine, it may also signal to the brain via neural circuits which in turn would regulate intestinal gluconeogenesis, May also control the production of hormones involved in whole-body energy homeostasis, May for instance, regulate blood pressure through renin secretion, May also regulate secretion of the PYY peptide by enteroendocrine cells and control gut motility, intestinal transit rate, and the harvesting of energy from SCFAs produced by gut microbiota, May also indirectly regulate the production of LEP/Leptin, a hormone acting on the CNS to inhibit food intake, in response to the presence of short-chain fatty acids in the intestine, Finally, may also play a role in glucose homeostasis, Besides its role in energy homeostasis, may play a role in intestinal immunity, May mediate the activation of the inflammatory and immune response by SCFAs in the gut, regulating the rapid production of chemokines and cytokines by intestinal epithelial cells, Among SCFAs, the fatty acids containing less than 6 carbons, the most potent activators are probably propionate, butyrate and pentanoate while acetate is a poor activator (PubMed:12496283, PubMed:12711604)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES", "length": 346, "molWeight": 38649, "crc64": "B3B19D62D11B6BA1", "md5": "2E42FF586DF2D4D663141F7404157511"}}
{"primaryAccession": "O14925", "text": "This is Mitochondrial import inner membrane translocase subunit Tim23 protein, from Human, contains 209 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14925", "organism_name": "Human", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim23", "length": 209, "firstPublicDate": "2001-10-18", "FUNCTION": "Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the Tim17/Tim22/Tim23 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEGGGGSGNKTTGGLAGFFGAGGAGYSHADLAGVPLTGMNPLSPYLNVDPRYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCMTGAAFGAMNGLRLGLKETQNMAWSKPRNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTVAAGTMTGMLYKCTGGLRGIARGGLTGLTLTSLYALYNNWEHMKGSLLQQSL", "length": 209, "molWeight": 21943, "crc64": "C9A1BBEC703B6838", "md5": "E1D19FC28A5C85E637672BCDC2EE5CBB"}}
{"primaryAccession": "O15091", "text": "This is Mitochondrial ribonuclease P catalytic subunit protein, from Human, contains 583 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O15091", "organism_name": "Human", "protein_name": "Mitochondrial ribonuclease P catalytic subunit", "length": 583, "firstPublicDate": "1998-07-15", "FUNCTION": "Catalytic ribonuclease component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends (PubMed:18984158, PubMed:25953853, PubMed:34715011), The presence of TRMT10C/MRPP1, HSD17B10/MRPP2 is required to catalyze tRNA molecules in their 5'-ends (PubMed:25953853)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the PPR family, P subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTFYLFGIRSFPKLWKSPYLGLGPGHSYVSLFLADRCGIRNQQRLFSLKTMSPQNTKATNLIAKARYLRKDEGSNKQVYSVPHFFLAGAAKERSQMNSQTEDHALAPVRNTIQLPTQPLNSEEWDKLKEDLKENTGKTSFESWIISQMAGCHSSIDVAKSLLAWVAAKNNGIVSYDLLVKYLYLCVFHMQTSEVIDVFEIMKARYKTLEPRGYSLLIRGLIHSDRWREALLLLEDIKKVITPSKKNYNDCIQGALLHQDVNTAWNLYQELLGHDIVPMLETLKAFFDFGKDIKDDNYSNKLLDILSYLRNNQLYPGESFAHSIKTWFESVPGKQWKGQFTTVRKSGQCSGCGKTIESIQLSPEEYECLKGKIMRDVIDGGDQYRKTTPQELKRFENFIKSRPPFDVVIDGLNVAKMFPKVRESQLLLNVVSQLAKRNLRLLVLGRKHMLRRSSQWSRDEMEEVQKQASCFFADDISEDDPFLLYATLHSGNHCRFITRDLMRDHKACLPDAKTQRLFFKWQQGHQLAIVNRFPGSKLTFQRILSYDTVVQTTGDSWHIPYDEDLVERCSCEVPTKWLCLHQKT", "length": 583, "molWeight": 67315, "crc64": "6AB17E7E8820D818", "md5": "703DC473CE244CD127BEFF083C49F402"}}
{"primaryAccession": "O15226", "text": "This is NF-kappa-B-repressing factor protein, from Human, contains 690 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O15226", "organism_name": "Human", "protein_name": "NF-kappa-B-repressing factor", "length": 690, "firstPublicDate": "1998-07-15", "FUNCTION": "Enhances the ATPase activity of DHX15 by acting like a brace that tethers mobile sections of DHX15 together, stabilizing a functional conformation with high RNA affinity of DHX15 (PubMed:12381793), Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity (PubMed:12381793), Also involved in the regulation of IL-8 transcription (PubMed:12381793), May also act as a DNA-binding transcription regulator: interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes (PubMed:10562553)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEKILQMAEGIDIGEMPSYDLVLSKPSKGQKRHLSTCDGQNPPKKQAGSKFHARPRFEPVHFVASSSKDERQEDPYGPQTKEVNEQTHFASMPRDIYQDYTQDSFSIQDGNSQYCDSSGFILTKDQPVTANMYFDSGNPAPSTTSQQANSQSTPEPSPSQTFPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHTFGEDLVVCQIGMSSYEFPPALKPPEDLVVLGKDASGQPIFNASAKHWTNFVITENANDAIGILNNSASFNKMSIEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKILQKTQPTYPSVKSSQCHTGSSPRGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKTVKYEAAGEAVKTLKKTQPTVINNLKKGAVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHTDLTFSRELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 690, "molWeight": 77673, "crc64": "3067A52671A7AE8F", "md5": "6FAF866D62F4D7E56AEA5952EB36A1CB"}}
{"primaryAccession": "O15245", "text": "This is Solute carrier family 22 member 1 protein, from Human, contains 554 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O15245", "organism_name": "Human", "protein_name": "Solute carrier family 22 member 1", "length": 554, "firstPublicDate": "2008-05-20", "FUNCTION": "Not able to uptake 1-methyl-4-phenylpyridinium (MPP(+))", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKENTIYLKVQTSEPSGT", "length": 554, "molWeight": 61154, "crc64": "55206B897DE32202", "md5": "9AE5ED4189FCBE8CD34B78502B42AAB2"}}
{"primaryAccession": "O15344", "text": "This is E3 ubiquitin-protein ligase Midline-1 protein, from Human, contains 667 amino acids, has 1 RING-type Zinc finger, has 2 B box-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [10, 60], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [116, 165], "description": "B box-type", "keyword_description": "Zinc finger", "textural_description": "B box-type Zinc finger"}, {"location": [172, 212], "description": "B box-type", "keyword_description": "Zinc finger", "textural_description": "B box-type Zinc finger"}], "meta_data": {"primaryAccession": "O15344", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase Midline-1", "length": 667, "firstPublicDate": "2002-08-30", "FUNCTION": "Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TRIM/RBCC family", "domain_description": {"RING-type Zinc finger": 1, "B box-type Zinc finger": 2}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHLDCTEQLP", "length": 667, "molWeight": 75251, "crc64": "673C5120018BA619", "md5": "8497C22AA39E3B05D610C6CA4E6F95A8"}}
{"primaryAccession": "O15503", "text": "This is Insulin-induced gene 1 protein protein, from Human, contains 277 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O15503", "organism_name": "Human", "protein_name": "Insulin-induced gene 1 protein", "length": 277, "firstPublicDate": "2000-05-30", "FUNCTION": "Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR (PubMed:12202038, PubMed:12535518, PubMed:16168377, PubMed:16399501, PubMed:16606821, PubMed:32322062), Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2 (PubMed:12202038, PubMed:16399501, PubMed:32322062), Binds oxysterol, including 25-hydroxycholesterol, regulating interaction with SCAP and retention of the SCAP-SREBP complex in the endoplasmic reticulum (PubMed:32322062), In presence of oxysterol, interacts with SCAP, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing SCAP from escorting SREBF1/SREBP1 and SREBF2/SREBP2 to the Golgi (PubMed:15899885, PubMed:32322062), Sterol deprivation or phosphorylation by PCK1 reduce oxysterol-binding, disrupting the interaction between INSIG1 and SCAP, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBF1/SREBP1 and SREBF2/SREBP2 (PubMed:32322062), Also regulates cholesterol synthesis by regulating degradation of HMGCR: initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligases AMFR/gp78 and/or RNF139 (PubMed:12535518, PubMed:16168377, PubMed:22143767), Also regulates degradation of SOAT2/ACAT2 when the lipid levels are low: initiates the ubiquitin-mediated degradation of SOAT2/ACAT2 via recruitment of the ubiquitin ligases AMFR/gp78 (PubMed:28604676)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the INSIG family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPRLHDHFWSCSCAHSARRRGPPRASAAGLAAKVGEMINVSVSGPSLLAAHGAPDADPAPRGRSAAMSGPEPGSPYPNTWHHRLLQRSLVLFSVGVVLALVLNLLQIQRNVTLFPEEVIATIFSSAWWVPPCCGTAAAVVGLLYPCIDSHLGEPHKFKREWASVMRCIAVFVGINHASAKLDFANNVQLSLTLAALSLGLWWTFDRSRSGLGLGITIAFLATLITQFLVYNGVYQYTSPDFLYIRSWLPCIFFSGGVTVGNIGRQLAMGVPEKPHSD", "length": 277, "molWeight": 29987, "crc64": "198068D53C658A58", "md5": "D2D017A358E781F82BE47760C505C53C"}}
{"primaryAccession": "O15525", "text": "This is Transcription factor MafG protein, from Human, contains 162 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O15525", "organism_name": "Human", "protein_name": "Transcription factor MafG", "length": 162, "firstPublicDate": "2000-05-30", "FUNCTION": "Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (PubMed:11154691), However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to specific DNA-binding sites (PubMed:8932385, PubMed:9421508, PubMed:11154691), Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor (PubMed:11154691), Transcription factor, component of erythroid-specific transcription factor NFE2L2 (PubMed:11154691), Activates globin gene expression when associated with NFE2L2 (PubMed:11154691), May be involved in signal transduction of extracellular H(+) (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family, Maf subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS", "length": 162, "molWeight": 17850, "crc64": "E49F1FBA230F8D30", "md5": "688EC34DBDB4555EB51B64C122AC0779"}}
{"primaryAccession": "O16011", "text": "This is Protein muscleblind protein, from Fruit fly, contains 297 amino acids, has 2 C3H1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [18, 46], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [52, 80], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "O16011", "organism_name": "Fruit fly", "protein_name": "Protein muscleblind", "length": 297, "firstPublicDate": "2001-11-16", "FUNCTION": "Required for terminal differentiation of photoreceptor cells, Vital for embryonic development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the muscleblind family", "domain_description": {"C3H1-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MANVVNMNSLLNGKDSRWLQLEVCREFQRNKCSRQDTECKFAHPPANVEVQNGKVTACYDSIKGRCNRDKPPCKYFHPPQHLKDQLLINGRNHLALKNALMQQMGIAPGQPVISGQVPAVATNPYLTGIPANSYSPYYTTGHLVPALLGPDPVTSQLGPVVPQTVQVAQQKIPRSDRLETSPLAAHHHQQQQQLQHQLNNINNNNNHSTAGAAATSTTATTTTNNAAAAAAAAAAAAAAAVMGHHTLEVGKKRAADTTDMFPLVFFCSFPSPCVFAFLNCSIFGFLRLWFSLFNLRH", "length": 297, "molWeight": 32330, "crc64": "37D430C798D91185", "md5": "2B77D77973D21E9B370CE35DEDB29E5A"}}
{"primaryAccession": "O16259", "text": "This is Stress-induced-phosphoprotein 1 protein, from Caenorhabditis elegans, contains 320 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O16259", "organism_name": "Caenorhabditis elegans", "protein_name": "Stress-induced-phosphoprotein 1", "length": 320, "firstPublicDate": "2013-04-03", "FUNCTION": "Plays a role in gonad development, Up-regulates longevity and thermotolerance, Binds daf-21/hsp90 and inhibits its ATPase activity", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTDAAIAEKDLGNAAYKQKDFEKAHVHYDKAIELDPSNITFYNNKAAVYFEEKKFAECVQFCEKAVEVGRETRADYKLIAKAMSRAGNAFQKQNDLSLAVQWFHRSLSEFRDPELVKKVKELEKQLKAAERLAYINPELAQEEKNKGNEYFKKGDYPTAMRHYNEAVKRDPENAILYSNRAACLTKLMEFQRALDDCDTCIRLDSKFIKGYIRKAACLVAMREWSKAQRAYEDALQVDPSNEEAREGVRNCLRSNDEDPEKAKERSLADPEVQEILRDPGMRMILEQMSNDPGAVREHLKNPEIFQKLMKLRDAGVIQMR", "length": 320, "molWeight": 36962, "crc64": "9D21907275A09780", "md5": "08E68FDC1A68C983C27C775DAB9C7D93"}}
{"primaryAccession": "O20250", "text": "This is Transketolase, chloroplastic protein, from Spinach, contains 741 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O20250", "organism_name": "Spinach", "protein_name": "Transketolase, chloroplastic", "length": 741, "firstPublicDate": "2005-06-21", "FUNCTION": "Catalyzes the reversible transfer of a two-carbon ketol group from fructose-6-phosphate or sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to yield xylulose-5-phosphate and erythrose-4-phosphate or ribose-5-phosphate, respectively", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the transketolase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAASSSLSTLSHHQTLLSHPKTHLPTTPASSLLVPTTSSKVNGVLLKSTSSSRRLRVGSASAVVRAAAVEALESTDIDQLVEKSVNTIRFLAIDAVEKANSGHPGLPMGCAPMGHILYDEIMRYNPKNPYWFNRDRFVLSAGHGCMLQYALLHLAGYDSVLEEDLKTFRQWGSRIPGHPENFETPGVEVTTGPLGQGIANAVGLALAEKHLAARFNKPDAEIVDHYTYVILGDGCQMEGIAQEACSLAGHWGLGKLIAFYDDNHISIDGDTAIAFTESVDLRFEALGWHVIWVKNGNTGYDEIRAAIKEAKTVTDKPTLIKVTTTIGFGSPNKSNSYSVHGSALGSKEVEATRQNLGWPYEPFHVPEEVKKHWSRHTPEGASLEAEWNTKFAEYEKKYPEDATEFKSITTGEFPAGWEKALPTYTPETPGDATRNLSQQCLNALAKVIPGLLGGSADLASSNMTLLKMFGDFRRTHRKKETFRFGVREHGMGAICNGICLHSPGFVPYCATFFVFTDYMRGAMRISALSEAGVIYVMTHDSIGLGEDGPTHQPIEALSKFPAMPNILMLRPADGNETAGSYKVAVENRKTPSILALSRKKLPNLPGTSIEGVEKGGYTITDNSSGNKPDVILIGTGSELEIAAKAGDELRKEGKAVRVVSFVSWELFEKQSDEYKESVLPSDVTARVSIEAGSTFGWHKIVGSKGKAIGIDKFGASAPAGKIYQEYGITVEAVVEAAKSVC", "length": 741, "molWeight": 80281, "crc64": "28871ED8568EAC8B", "md5": "6B887512BF368827F3B93DEF3ED5DD7E"}}
{"primaryAccession": "O22049", "text": "This is Ubiquinol oxidase 2, mitochondrial protein, from Mouse-ear cress, contains 353 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O22049", "organism_name": "Mouse-ear cress", "protein_name": "Ubiquinol oxidase 2, mitochondrial", "length": 353, "firstPublicDate": "1998-12-15", "FUNCTION": "Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation, May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the alternative oxidase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSQLITKAALRVLLVCGRGNCNMFVSSVSSTSVMKSPYEITAPMRIHDWCGGFGDFKIGSKHVQGNFNLRWMGMSSASAMEKKDENLTVKKGQNGGGSVAVPSYWGIETAKMKITRKDGSDWPWNCFMPWETYQANLSIDLKKHHVPKNIADKVAYRIVKLLRIPTDIFFQRRYGCRAMMLETVAAVPGMVGGMLLHLKSIRKFEHSGGWIKALLEEAENERMHLMTMMELVKPKWYERLLVMLVQGIFFNSFFVCYVISPRLAHRVVGYLEEEAIHSYTEFLKDIDNGKIENVAAPAIAIDYWRLPKDATLKDVVTVIRADEAHHRDVNHFASDIRNQGKELREAAAPIGYH", "length": 353, "molWeight": 40087, "crc64": "DF7ACB113E57A133", "md5": "0DF96820A26D5B082E5C24D39ABFDCAB"}}
{"primaryAccession": "O22131", "text": "This is LOB domain-containing protein 18 protein, from Mouse-ear cress, contains 262 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O22131", "organism_name": "Mouse-ear cress", "protein_name": "LOB domain-containing protein 18", "length": 262, "firstPublicDate": "2003-01-17", "FUNCTION": "Involved in the positive regulation of tracheary element (TE) differentiation, Involved in a positive feedback loop that maintains or promotes NAC030/VND7 expression that regulates TE differentiation-related genes (PubMed:19088331), Functions in the initiation and emergence of lateral roots, in conjunction with LBD16, downstream of ARF7 and ARF19 (PubMed:19717544, PubMed:23749813), Transcriptional activator that directly regulates EXPA14, a gene encoding a cell wall-loosening factor that promotes lateral root emergence, Activates EXPA14 by directly binding to a specific region of its promoter (PubMed:22974309), Transcriptional activator that directly regulates EXPA17, a gene encoding a cell wall-loosening factor that promotes lateral root emergence (PubMed:23872272), Acts downstream of the auxin influx carriers AUX1 and LAX1 in the regulation of lateral root initiation and development (PubMed:26059335)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the LOB domain-containing protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGGGNTITAVGGGGGGCGGGGSSGGGGSSGGGGGGPCGACKFLRRKCVPGCIFAPYFDSEQGSAYFAAVHKVFGASNVSKLLLHIPVHRRSDAVVTICYEAQARIRDPIYGCVAHIFALQQQVVNLQAEVSYLQAHLASLELPQPQTRPQPMPQPQPLFFTPPPPLAITDLPASVSPLPSTYDLASIFDQTTSSSAWATQQRRFIDPRHQYGVSSSSSSVAVGLGGENSHDLQALAHELLHRQGSPPPAATDHSPSRTMSR", "length": 262, "molWeight": 27219, "crc64": "4DE2F64EC148AEF5", "md5": "59613C715C88734E2E07045359DDB3CC"}}
{"primaryAccession": "O22315", "text": "This is Serine/arginine-rich-splicing factor SR34 protein, from Mouse-ear cress, contains 303 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O22315", "organism_name": "Mouse-ear cress", "protein_name": "Serine/arginine-rich-splicing factor SR34", "length": 303, "firstPublicDate": "1998-12-15", "FUNCTION": "General splicing factor, Can promote splice site selection in vitro presumably by antagonizing the effects of the A1 heterogeneous nuclear ribonucleoprotein, May have an essential function during early plant development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the splicing factor SR family, SR subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSRSSRTVYVGNLPGDIREREVEDLFSKYGPVVQIDLKVPPRPPGYAFVEFDDARDAEDAIHGRDGYDFDGHRLRVELAHGGRRSSDDTRGSFNGGGRGGGRGRGDGGSRGPSRRSEFRVLVTGLPSSASWQDLKDHMRKGGDVCFSQVYRDARGTTGVVDYTCYEDMKYALKKLDDTEFRNAFSNGYVRVREYDSRKDSRSPSRGRSYSKSRSRSRGRSVSRSRSRSRSRSRSPKAKSSRRSPAKSTSRSPGPRSKSRSPSPRRSRSRSRSPLPSVQKEGSKSPSKPSPAKSPIHTRSPSR", "length": 303, "molWeight": 33729, "crc64": "6530F9CB628B8EFA", "md5": "45C013D00405005505BA8239302869C9"}}
{"primaryAccession": "O22609", "text": "This is Protease Do-like 1, chloroplastic protein, from Mouse-ear cress, contains 439 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O22609", "organism_name": "Mouse-ear cress", "protein_name": "Protease Do-like 1, chloroplastic", "length": 439, "firstPublicDate": "2000-12-01", "FUNCTION": "Serine protease that is required at high temperature, May be involved in the degradation of damaged proteins, In vivo, can degrade beta-casein", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the peptidase S1C family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATTTSCSLLLSSTLFLHSPPSSHLSFFNLSSSRSSPISLYPIRSKRYFRILSKLSLNDNNRDDDDDTLHFTPFSAVKPFFLLCTSVALSFSLFAASPAVESASAFVVSTPKKLQTDELATVRLFQENTPSVVYITNLAVRQDAFTLDVLEVPQGSGSGFVWDKQGHIVTNYHVIRGASDLRVTLADQTTFDAKVVGFDQDKDVAVLRIDAPKNKLRPIPVGVSADLLVGQKVFAIGNPFGLDHTLTTGVISGLRREISSAATGRPIQDVIQTDAAINPGNSGGPLLDSSGTLIGINTAIYSPSGASSGVGFSIPVDTVGGIVDQLVRFGKVTRPILGIKFAPDQSVEQLGVSGVLVLDAPPSGPAGKAGLQSTKRDGYGRLVLGDIITSVNGTKVSNGSDLYRILDQCKVGDEVTVEVLRGDHKEKISVTLEPKPDES", "length": 439, "molWeight": 46674, "crc64": "05EB437DCE71A251", "md5": "FF5FFD6E066073073DD83399FE421D50"}}
{"primaryAccession": "O23179", "text": "This is Patatin-like protein 1 protein, from Mouse-ear cress, contains 414 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O23179", "organism_name": "Mouse-ear cress", "protein_name": "Patatin-like protein 1", "length": 414, "firstPublicDate": "2014-03-19", "FUNCTION": "Possesses non-specific lipolytic acyl hydrolase (LAH) activity, Catalyzes the hydrolysis of the neutral lipids monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG) and phosphatidylglycerol (PG), and less efficiently the polar lipids phosphatidylcholine (PC) and phosphatidylinositol (PI), but not the storage lipid triacylglycerol (TAG), May play a role in root development", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the patatin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MENKSPSKKNKPPSCGSLVTILSLDGGGVRGIIAGVILAFLEKQLQELDGEEARLADYFDVIAGTSTGGLVTAMLTVPDETGRPHFAAKDIVPFYLEHCPKIFPQPTGVLALLPKLPKLLSGPKYSGKYLRNLLSKLLGETRLHQTLTNIVIPTFDIKKLQPTIFSSYQLLVDPSLDVKVSDICIGTSAAPTFFPPHYFSNEDSQGNKTEFNLVDGAVTANNPTLVAMTAVSKQIVKNNPDMGKLKPLGFDRFLVISIGTGSTKREEKYSAKKAAKWGIISWLYDDGSTPILDITMESSRDMIHYHSSVVFKALQSEDKYLRIDDDTLEGDVSTMDLATKSNLENLQKIGEKMLTNRVMQMNIDTGVYEPVAENITNDEQLKRYAKILSDERKLRRLRSDTMIKDSSNESQEIK", "length": 414, "molWeight": 45824, "crc64": "078E35777043AF43", "md5": "CB3EEF979BD3E8C41F22110236D4439C"}}
{"primaryAccession": "O23181", "text": "This is Patatin-like protein 3 protein, from Mouse-ear cress, contains 428 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O23181", "organism_name": "Mouse-ear cress", "protein_name": "Patatin-like protein 3", "length": 428, "firstPublicDate": "2014-03-19", "FUNCTION": "Possesses non-specific lipolytic acyl hydrolase (LAH) activity, Catalyzes the hydrolysis of the neutral lipids monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG) and phosphatidylglycerol (PG), and less efficiently the polar lipids phosphatidylcholine (PC) and phosphatidylinositol (PI), but not the storage lipid triacylglycerol (TAG), May play a role in root development", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the patatin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDTERGSISSSEISRTAHLQDRTVACLPPSYGQLVTILSIDGGGIRGIIPGTILAYLESQLQELDGEEARLVDYFDVISGTSTGGLIVAMLTAQDQSGGHSRNSNRPLFEAKEIVPFYLKHSPKIFPQPRGIFCGWGETIVRLVGGPKFNGKYLHDLVEGFLGDTKLTQSLTNVVIPCFDIKKLQPVIFSSYQAVNNQAMNAKLSDICISTSAAPTFFPAHRFTNEDSEGIKHEFNLIDGGIAANNPTLCAIAEVTKQIIKKNPVMGDISPLDFTRFLVISIGTGSIRNQEKYNAKMASKWGLMCWVFESGSTPILDCYSEAIHDMVDYQSSVVFQALRSEKNYLRIDDDSLKGDLGSVDISTEKNMEGLVEVGEALLKKRVSRVNLESGHYQPISENVTNEEALKRFAKVLSEERKLRESRSPKLKI", "length": 428, "molWeight": 47204, "crc64": "0EF73611D4940B84", "md5": "DF108AF427808F701CF89CA8A4F7D998"}}
{"primaryAccession": "O23463", "text": "This is Calmodulin-binding transcription activator 5 protein, from Mouse-ear cress, contains 923 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O23463", "organism_name": "Mouse-ear cress", "protein_name": "Calmodulin-binding transcription activator 5", "length": 923, "firstPublicDate": "2006-01-24", "FUNCTION": "Transcription activator (PubMed:14581622), Binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3' (By similarity), Regulates transcriptional activity in response to calcium signals (Probable), Binds calmodulin in a calcium-dependent manner (By similarity), Involved in response to cold, Contributes together with CAMTA3 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CAMTA family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGVDSGKLIGSEIHGFHTLQDLDIQTMLDEAYSRWLRPNEIHALLCNHKFFTINVKPVNLPKSGTIVLFDRKMLRNFRKDGHNWKKKKDGKTIKEAHEHLKVGNEERIHVYYAHGEDTPTFVRRCYWLLDKSQEHIVLVHYRETHEVHAAPATPGNSYSSSITDHLSPKIVAEDTSSGVHNTCNTGFEVRSNSLGSRNHEIRLHEINTLDWDELLVPADISNQSHPTEEDMLYFTEQLQTAPRGSVKQGNHLAGYNGSVDIPSFPGLEDPVYQNNNSCGAGEFSSQHSHCGVDPNLQRRDFSATVTDQPGDALLNNGYGSQDSFGRWVNNFISDSPGSVDDPSLEAVYTPGQDSSTPPTVFHSHSDIPEQVFNITDVSPAWAYSTEKTKILVTGFFHDSFQHLGRSNLICICGELRVPAEFLQMGVYRCFLPPQSPGVVNLYLSVDGNKPISQLFSFEHRSVQFIEKAIPQDDQLYKWEEFEFQVRLAHLLFTSSNKISVLTSKISPENLLEAKKLASRTSHLLNSWAYLMKSIQANEVPFDQARDHLFELTLKNRLKEWLLEKVIENRNTKEYDSKGLGVIHLCAVLGYTWSILLFSWANISLDFRDKQGWTALHWAAYYGREKMVAALLSAGARPNLVTDPTKEFLGGCTAADLAQQKGYDGLAAFLAEKCLVAQFKDMQTAGNISGNLETIKAEKSSNPGNANEEEQSLKDTLAAYRTAAEAAARIQGAFREHELKVRSSAVRFASKEEEAKNIIAAMKIQHAFRNFEVRRKIAAAARIQYRFQTWKMRREFLNMRKKAIRIQAAFRGFQVRRQYQKITWSVGVLEKAILRWRLKRKGFRGLQVSQPDEKEGSEAVEDFYKTSQKQAEERLERSVVKVQAMFRSKKAQQDYRRMKLAHEEAQLEYDGMQELDQMATEES", "length": 923, "molWeight": 104847, "crc64": "AAA73F4A14E9A5DA", "md5": "F6586A3FFECED27D841A287FEE875451"}}
{"primaryAccession": "O23647", "text": "This is 1,4-alpha-glucan-branching enzyme 2-1, chloroplastic/amyloplastic protein, from Mouse-ear cress, contains 858 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O23647", "organism_name": "Mouse-ear cress", "protein_name": "1,4-alpha-glucan-branching enzyme 2-1, chloroplastic/amyloplastic", "length": 858, "firstPublicDate": "2012-01-25", "FUNCTION": "Catalyzes the formation of the alpha-1,6-glucosidic linkages in starch by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the glycosyl hydrolase 13 family, GlgB subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVYTISGVRFPHLPSIKKKNSSLHSFNEDLRRSNAVSFSLRKDSRSSGKVFARKPSYDSDSSSLATTASEKLRGHQSDSSSSASDQVQSRDTVSDDTQVLGNVDVQKTEEAQETETLDQTSALSTSGSISYKEDFAKMSHSVDQEVGQRKIPPPGDGKRIYDIDPMLNSHRNHLDYRYGQYRKLREEIDKNEGGLEAFSRGYEIFGFTRSATGITYREWAPGAKAASLIGDFNNWNAKSDVMARNDFGVWEIFLPNNADGSPAIPHGSRVKIRMDTPSGIKDSIPAWIKYSVQPPGEIPYNGVYYDPPEEDKYAFKHPRPKKPTSLRIYESHVGMSSTEPKINTYANFRDDVLPRIKKLGYNAVQIMAIQEHAYYASFGYHVTNFFAPSSRFGTPDDLKSLIDKAHELGLVVLMDIVHSHASKNTLDGLDMFDGTDGQYFHSGSRGYHWMWDSRLFNYGSWEVLRYLLSNARWWLEEYKFDGFRFDGVTSMMYTHHGLQVEFTGNYNEYFGYSTDVDAVVYLMLVNDLIHGLYPEAIVVGEDVSGMPAFCVPVEDGGVGFDYRLHMAVADKWIELLKKRDEDWQVGDITFTLTNRRWGEKCVVYAESHDQALVGDKTIAFWLMDKDMYDFMAVDRQATPRVDRGIALHKMIRLITMGLGGEGYLNFMGNEFGHPEWIDFPRTDQHLPDGRVIAGNNGSYDKCRRRFDLGDAEYLRYHGLQEFDRAMQNLEETYGFMTSEHQYISRKDEGDRVIVFERGNLLFVFNFHWTNSYSDYRIGCSVPGKYKIVLDSDNSLFGGFNRLDDSAEFFTSDGRHDDRPCSFMVYAPCRTAVVYAAVDDDDDDERSSLVPIGLLPEDV", "length": 858, "molWeight": 97660, "crc64": "E1D61C0C21D456F1", "md5": "D0D0586A273D446C73D0DCCFE9BAE671"}}
{"primaryAccession": "O23722", "text": "This is Diphosphomevalonate decarboxylase MVD1, peroxisomal protein, from Mouse-ear cress, contains 412 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O23722", "organism_name": "Mouse-ear cress", "protein_name": "Diphosphomevalonate decarboxylase MVD1, peroxisomal", "length": 412, "firstPublicDate": "2016-02-17", "FUNCTION": "Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids (PubMed:10344201, PubMed:26216978), Is specific for (R)-5-diphosphomevalonate (MVAPP), The catalytic efficiency with (R)-5-phosphomevalonate (MVAP) as substrate is 10000-fold lower than for MVAPP (PubMed:26216978), Can complement a yeast mutant defective in MVD activity (PubMed:10344201)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the diphosphomevalonate decarboxylase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAEEKWVVMVTAQTPTNIAVIKYWGKRDEVRILPINDSISVTLDPDHLCTLTTVAVSPSFDRDRMWLNGKEISLSGSRYQNCLREIRSRADDVEDKEKGIKIAKKDWEKLHLHIASHNNFPTAAGLASSAAGFACLVFALAKLMNVNEDPSQLSAIARQGSGSACRSLFGGFVKWNMGNKEDGSDSVAVQLVDDKHWDDLVIIIAVVSSRQKETSSTSGMRESVETSLLLQHRAKEVVPVRILQMEEAIKNRDFTSFTKLTCSDSNQFHAVCMDTSPPIFYMNDTSHRIISLVEKWNRSAGTPEIAYTFDAGPNAVMIARNRKVAVELLQGLLYCFPPKPDTDMKSYVLGDTSIVKEAGLEGELPQGIKDKIGSQDQKGEVSYFICSRPGRGPVVLQDQTQALLHPQTGLPK", "length": 412, "molWeight": 45586, "crc64": "2387AD2F2B84EEA5", "md5": "7959C0D826ABB35AD798EA47C49FCD33"}}
{"primaryAccession": "O24174", "text": "This is Betaine aldehyde dehydrogenase 1 protein, from Rice, contains 505 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O24174", "organism_name": "Rice", "protein_name": "Betaine aldehyde dehydrogenase 1", "length": 505, "firstPublicDate": "1998-12-15", "FUNCTION": "Dehydrogenase that can use N-acetyl-gamma-aminobutyraldehyde (NAGABald), gamma-guanidinobutyraldehyde (GGBald), betaine aldehyde (Bet-ald), gamma-aminobutyraldehyde (GAB-ald), acetaldehyde, 4-aminobutylaldehyde (AB-ald), 3-aminopropionaldehyde (AP-ald), 4-N-trimethylaminobutyraldehyde (TMAB-ald) and 3-N-trimethylaminopropionaldehyde (TMAP-ald) as substrates, Catalyzes the oxidation of GAB-ald more efficiently than Bet-ald, May convert acetaldehyde into acetate, thus facilitating the production of acetyl-CoA in peroxisomes under anaerobic conditions", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the aldehyde dehydrogenase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAPSAIPRRGLFIGGGWREPSLGRRLPVVNPATEATIGDIPAATAEDVELAVSAARDAFGRDGGRHWSRAPGAVRAKYLKAIAAKIKDKKSYLALLETLDSGKPLDEAAGDMEDVAACFEYYADLAEALDGKQRAPISLPMENFESYVLKEPIGVVGLITPWNYPLLMATWKVAPALAAGCTAVLKPSELASLTCLELGGICAEIGLPPGVLNIITGLGTEAGAPLASHPHVDKIAFTGSTETGKRIMITASQMVKPVSLELGGKSPLIVFDDVDIDKAVEWAMFGCFANAGQVCSATSRLLLHEKIAKRFLDRLVAWAKSIKISDPLEEGCRLGSVVSEGQYQKIMKFISTARCEGATILYGGARPQHLKRGFFIEPTIITNVSTSMQIWREEVFGPVICVKEFRTEREAVELANDTHYGLAGAVISNDLERCERISKAIQSGIVWINCSQPCFVQAPWGGNKRSGFGRELGQWGLDNYLSVKQVTKYCSDEPYGWYRPPSKL", "length": 505, "molWeight": 54648, "crc64": "85EFA42B059A8081", "md5": "6E79ECAD88759492333652E1ECFFA78D"}}
{"primaryAccession": "O35254", "text": "This is Golgi reassembly-stacking protein 1 protein, from Rat, contains 451 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O35254", "organism_name": "Rat", "protein_name": "Golgi reassembly-stacking protein 1", "length": 451, "firstPublicDate": "2004-08-16", "FUNCTION": "Key structural protein of the Golgi apparatus (By similarity), The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon (By similarity), Acting in concert with GORASP2/GRASP55, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks (By similarity), However, other studies suggest that GORASP1 plays an important role in assembly and membrane stacking of the cisternae, and in the reassembly of Golgi stacks after breakdown during mitosis (PubMed:12839990, PubMed:23940043, PubMed:9346242), Caspase-mediated cleavage of GORASP1 is required for fragmentation of the Golgi during apoptosis (PubMed:11815631, PubMed:12015985), Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes (By similarity), Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane (By similarity)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GORASP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGLGASSEQPAGGEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPAALAGLRPYTDYIVGSDQILQESEDFFTLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPSSQYKKPPSASSPGTPAKTPQPNAFPLGAPPPWPIPQDSSGPELGSRQSDYMEALPQVPGGFMEEQLPGPGSPGHGTADYGGCLHSMEIPLQPPPPVQRVMDPGFLDVSGMSLLDSNNTSVCPSLSSSSLLTPTAVSALGPEDIGSSSSSHERGGEATWSGSEFEISFPDSPGSQAQVDHLPRLTLPDGLTSAASPEEGLSAELLEAQTEEPAHTASLDCMAQTEGPAGQVQAAPDPEPGLCEGPW", "length": 451, "molWeight": 47673, "crc64": "5B38FADF2E255EA3", "md5": "0E6BD6387E1D9366974C1FDBA2D96CD9"}}
{"primaryAccession": "O35615", "text": "This is Zinc finger protein ZFPM1 protein, from Mouse, contains 995 amino acids, has 5 CCHC FOG-type Zinc finger, has 4 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [249, 282], "description": "CCHC FOG-type", "keyword_description": "Zinc finger", "textural_description": "CCHC FOG-type Zinc finger"}, {"location": [303, 327], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [333, 355], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [361, 384], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [584, 617], "description": "CCHC FOG-type", "keyword_description": "Zinc finger", "textural_description": "CCHC FOG-type Zinc finger"}, {"location": [690, 723], "description": "CCHC FOG-type", "keyword_description": "Zinc finger", "textural_description": "CCHC FOG-type Zinc finger"}, {"location": [830, 863], "description": "CCHC FOG-type", "keyword_description": "Zinc finger", "textural_description": "CCHC FOG-type Zinc finger"}, {"location": [868, 891], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [957, 990], "description": "CCHC FOG-type", "keyword_description": "Zinc finger", "textural_description": "CCHC FOG-type Zinc finger"}], "meta_data": {"primaryAccession": "O35615", "organism_name": "Mouse", "protein_name": "Zinc finger protein ZFPM1", "length": 995, "firstPublicDate": "2004-03-15", "FUNCTION": "Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation, Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3, Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context, The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1, May be involved in regulation of some genes in gonads, May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the FOG (Friend of GATA) family", "domain_description": {"CCHC FOG-type Zinc finger": 5, "C2H2-type Zinc finger": 4}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRRKQSNPRQIKRSLRDMEAGEEAKAMDSSPKEQEAPDPEAPAIEEPPSPPREDVSPPAVPAPPESPEDPEDMEGQELEMRPQDEEKEEKEEEAAMASPWSGPEELELALQDGQRCVRARLSLTEGLSWGPFYGSIQTRALSPEREEPGPAVTLMVDESCWLRMLPQVLTEEAANSEIYRKDDALWCRVTKVVPSGGLLYVRLVTEPHGAPRHPVQEPVEPGGLAPVHTDIQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERNLQAHLLYYCASRQRAGSPVSATEEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCHNCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPAAKLPPDSLAGFQQHSLMHSPLVPADKAPTPSSGLDSKAEVTNGETRVPPQNGGSSESPAAPRTIKVEAAEEPEATRASGPGEPGPQAPSRTPSPHSPNPVRVKTELSSPTPGSSPGPGELTMAGTLFLPQYVFSPDAGTTTVPTAPQASEILAKMSELVHNRLQQGAGSSGAAGTPTGLFSGTKGATCFECEITFNNINNFYVHKRLYCSGRRAPEDPPTVRRPKAATGPARAPAGAAAEPDPSRSSPGPGPREEEASGTTTPEAEAAGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPPAPTTAPGPAAPALTAPPVRTRRRRKLYELPAAGAPPPAAGPAPVPVVPSPTAELPSSPRPGSASAGPAPALSPSPVPDGPIDLSKRPRRQSPDAPTALPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPLRTTALCPYCPPNGRVRGDLVEHLRQAHGLQVAKPAASPGAEPRTPAERAPRDSPDGRAPRSPSPAPENTPSDPADQGARTPSKGPPAPAPAPGGGGGHRYCRLCNIRFSSLSTFIAHKKYYCSSHAAEHVK", "length": 995, "molWeight": 105984, "crc64": "293255B28151ECB8", "md5": "E7F7801A98E138BDB5D6D6AC9AD5F502"}}
{"primaryAccession": "O35621", "text": "This is Phosphomannomutase 1 protein, from Mouse, contains 262 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O35621", "organism_name": "Mouse", "protein_name": "Phosphomannomutase 1", "length": 262, "firstPublicDate": "2001-01-24", "FUNCTION": "Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions, In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic PMM family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAVAVEGARRKERILCLFDVDGTLTPARQKIDPEVSAFLQKLRSRVQIGVVGGSDYSKIAEQLGEGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNVSPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRYCLDSLDEDSFDIIHFFGNETSPGGNDFEIYADPRTVGHSVVSPQDTVQRCRELFFPETAHEA", "length": 262, "molWeight": 29775, "crc64": "2967154C0FF292B0", "md5": "3128B4113E77BED695345C46B46E504B"}}
{"primaryAccession": "O42248", "text": "This is Small ribosomal subunit protein RACK1 protein, from Zebrafish, contains 317 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42248", "organism_name": "Zebrafish", "protein_name": "Small ribosomal subunit protein RACK1", "length": 317, "firstPublicDate": "1998-07-15", "FUNCTION": "Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules, Interacts with a wide variety of proteins and plays a role in many cellular processes (By similarity), Required for VANGL2 membrane localization, inhibits Wnt signaling and regulates cellular polarization and oriented cell division during gastrulation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the WD repeat G protein beta family, Ribosomal protein RACK1 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTEQMTVRGTLKGHSGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDDSHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDTINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELRQDIITTNSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQVTIGTR", "length": 317, "molWeight": 35123, "crc64": "DEC80E241A22808B", "md5": "B336074CA9B6263CEACCBEF38CDBB0C8"}}
{"primaryAccession": "O42250", "text": "This is Visual system homeobox 1 protein, from Zebrafish, contains 344 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42250", "organism_name": "Zebrafish", "protein_name": "Visual system homeobox 1", "length": 344, "firstPublicDate": "2002-11-08", "FUNCTION": "May be involved in maintenance as well as cellular differentiation of retinal interneurons, such as bipolar cells, May play a role in establishing interneuronal cell classes in nonsensory as well as sensory systems", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the paired homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTGREEATDEKPKVKLYPSFGIDKSRLNGSGFRSKGFAITDLLGLESELQPHQSGPGAGPNGEGQSAAVGGFSFPGGSLPLGLGFLCSLAAQQPPGAPCFLPSHIPLLQSRTESHFMQNLEQQRDVYSDDDCLSGDRNDGKNSGNSQKRKKRRHRTVFTSHQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESIINSAKSGMMGSCAPWLLGEPAGMHKKSMEIVKKAPGTPESTHSDTYSEEHKGKDSDTTWSSGANGADDSEDMAIDLSSTSKQENKSTLKRSPPRTENSSDSENES", "length": 344, "molWeight": 37872, "crc64": "5CA3C631D2F8E7F6", "md5": "DE5BB2718F74A2D48DDBB0C1665F6A04"}}
{"primaryAccession": "O42721", "text": "This is Cell wall mannoprotein 1 protein, from Penicillium marneffei, contains 462 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42721", "organism_name": "Penicillium marneffei", "protein_name": "Cell wall mannoprotein 1", "length": 462, "firstPublicDate": "2015-04-29", "FUNCTION": "Constitutive protein of the cell wall, Binds fatty acids and may thus serve as a fatty acid transporter between P,marneffei and host cells during infection (PubMed:20053994), Abundant antigen target of host humoral immune response (PubMed:9488383)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the cell wall mannoprotein 1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFLSSLVVLGLSAQALASPYVDHQATKDQRDVNVFKQVLQDINLDVQKFDQDITQYQGGDPTVLLADSDAIIKTTEEGIQRIGPQPPLSVTEALALVGPVQGVNKLIMKAVDHLIEKKGPLVGGGYGPQVKDSLERQAHAASKLSELVSSKVPSPLAPISKQLSDQVAQALQKGIQAFSISARQATKVKREATKVQRDISAFKKVIQNISLAVNKFNVDIERYVGGDASHLLADGNVLIKATLDGVQSLQNEPPLSSMEALALVGPVQDLSNQILLAIQNLIDKKEPLVQAGFGGKVENNLRQQEEAAQKLSELVSTKVPHELADISRQLSDGIAAGIKKGIDAFAGTGPAPTTSSTPEASTAPAPSTPPQTPEDTLVPATSTPAPGPAPTAPDSSMVWPTSTTASPDVQPTITSSGTSVPAAPTGGNSSPAVPAFTGAASANQVSGAVGLAAGLLAVLAF", "length": 462, "molWeight": 47895, "crc64": "3EAE5FBA4FC6A298", "md5": "A8BD4047950BD20E887560907C8527C1"}}
{"primaryAccession": "O42893", "text": "This is Cytosolic neutral trehalase protein, from Fission yeast, contains 735 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42893", "organism_name": "Fission yeast", "protein_name": "Cytosolic neutral trehalase", "length": 735, "firstPublicDate": "1998-12-15", "FUNCTION": "Hydrolyzes intracellular trehalose to glucose (PubMed:12153582), The disaccharide trehalose serves as a storage carbohydrate that is mobilized during nutrient stress and spore germination (PubMed:11094289), Together with tps1, regulates the level of trehalose as a protectant for cell integrity during heat, osmotic and oxidative stresses (PubMed:9495778, PubMed:9974219, PubMed:12943532, PubMed:15965643)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the glycosyl hydrolase 37 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPSKFSSKYVDTEAISNDDDNPFATAKSYYSKDTDLSTRVSAGRPRTLSTSMEASAAPTIPELKNLRRRGSLDEHKQPRKFLVDVDKTLNALLESEDTDRNMQITIEDTGPKVVSLGSASSGGYRLYELRGTYQLSNLLQELTLAKDYGRRYILLDERRLNENPVNRLSRLIKGTFWDALTRRIDASVLDVICRDTKDRSGSHVNRIYVPKAEQEMYEYYVRAAKERPYLNLQVEYLPEEITPEWVRDVNDKPGLLALAMEKYQDDEGNTHLRGVPFVVPGGRFNELYGWDSYFESLGLLVDDRVDLAKGMVENFIFEITYYGKILNANRTYYLLRSQPPFLTDMALRVYERIKNEEGSLDFLHRAFSATIKEYHTVWTATPRLDPKTGLSRYRPGGLGIPPETEASHFEHLLRPYMEKYHMTLEEFTHAYNYQQIHEPALDEYFVHDRAVRESGHDTTYRLEKVCADLATVDLNSLLYKYETDISHVILEYFDDKFVLPNGTIETSAIWDRRARARRAAMEKYLWSEADSMWYDYNTKLETKSTYESATAFWALWAGVATPRQAAKFVDVSLPKFEVAGGIVAGTKRSLGKVGLDNPSRQWDYPNGWSPQQILAWYGLIRYGYEEETRRLVYRWLYTITKSFVDFNGIVVEKYDLTRPVDPHRVEAEYGNQGVNIKGVAREGFGWVNASYEVGLTFCNSHMRRALGACTTPDVFFAGIKEESLPAFENLSIHKN", "length": 735, "molWeight": 84603, "crc64": "73FF979534E91BD4", "md5": "DA57CE38147725E59A700DF35D7DE0F2"}}
{"primaryAccession": "O43060", "text": "This is Eukaryotic translation initiation factor 3 subunit F protein, from Fission yeast, contains 302 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O43060", "organism_name": "Fission yeast", "protein_name": "Eukaryotic translation initiation factor 3 subunit F", "length": 302, "firstPublicDate": "2008-09-02", "FUNCTION": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome, The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eIF-3 subunit F family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALGTKHVLHLTKPSSRSSPLNIVIEPAVLFSILDHSTRKSENNQRVIGTLLGTRSEDGREIEIKSCFAVPHNESSEQVEVEMEYHRAMYHLHLKANPREVVVGWYATSPDLDAFSALIQNLYASPAEPGTAPLGTYPHPCVHLTVNTDVSSPLAIKTYVSSPVGITERLADSCAFVPTPFTIRDDEAVRSGLKAVAAPKNDPSRLASLFTDLQQLRRSTLELLSMIERVSDYVQNVIDGSSPANVAVGRYLMKCFSLIPCVEGQDFEKIFSSHLQDVLVVVYLANTLRTQVDIASRLNLLP", "length": 302, "molWeight": 33251, "crc64": "A046E087CF083D84", "md5": "0253007A1045D0E25D5C11F4D476A9A7"}}
{"primaryAccession": "O43257", "text": "This is Zinc finger HIT domain-containing protein 1 protein, from Human, contains 154 amino acids, has 1 HIT-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [117, 149], "description": "HIT-type", "keyword_description": "Zinc finger", "textural_description": "HIT-type Zinc finger"}], "meta_data": {"primaryAccession": "O43257", "organism_name": "Human", "protein_name": "Zinc finger HIT domain-containing protein 1", "length": 154, "firstPublicDate": "2004-04-13", "FUNCTION": "Plays a role in chromatin remodeling by promoting the incorporation of histone variant H2AZ1/H2A,Z into the genome to regulate gene expression (PubMed:20473270, PubMed:35175558), Promotes SRCAP complex-mediated deposition of histone variant H2AZ1 to lymphoid fate regulator genes, enhancing lymphoid lineage commitment (By similarity), Recruited to the promoter of the transcriptional activator MYOG at the early stages of muscle differentiation where it mediates binding of histone H2AZ1 to chromatin and induces muscle-specific gene expression (PubMed:20473270), Maintains hematopoietic stem cell (HSC) quiescence by determining the chromatin accessibility at distal enhancers of HSC quiescence genes such as PTEN, FSTL1 and KLF4, enhancing deposition of H2AZ1 to promote their sustained transcription and restricting PI3K-AKT signaling inhibition (By similarity), Plays a role in intestinal stem cell maintenance by promoting H2AZ1 deposition at the transcription start sites of genes involved in intestinal stem cell fate determination including LGR5, TGFB1 and TGFBR2, thereby contributing to gene transcription (By similarity), Promotes phosphorylation of the H2AZ1 chaperone VPS72/YL1 which enhances the interaction between HZAZ1 and VPS72 (By similarity), Regulates the entry of male germ cells into meiosis by controlling histone H2AZ1 deposition which facilitates the expression of meiotic genes such as MEIOSIN, leading to the initiation of meiosis (By similarity), Required for postnatal heart function through its role in maintenance of cardiac Ca(2+) homeostasis by modulating the expression of Ca(2+)-regulating proteins CASQ1 and ATP2A2/SERCA2A via deposition of histone H2AZ1 at their promoters (By similarity), During embryonic heart development, required for mitochondrial maturation and oxidative metabolism by functioning through H2AZ1 deposition to activate transcription of metabolic genes and is also required to maintain the stability of the respiratory complex (By similarity), In neural cells, increases deposition of the H2AZ1 histone variant and promotes neurite growth (PubMed:35175558), Plays a role in TP53/p53-mediated apoptosis induction by stimulating the transcriptional activation of several proapoptotic p53 target genes such as PMAIP1/NOXA and BBC3/PUMA (PubMed:17380123), Mediates cell cycle arrest induced in response to gamma-irradiation by enhancing recruitment of TP53/p53 to the promoter of the cell cycle inhibitor CDKN1A, leading to its transcriptional activation (PubMed:17700068), Recruited to the promoter of cyclin-dependent kinase CDK6 and inhibits its transcription, possibly by decreasing the acetylation level of histone H4, leading to cell cycle arrest at the G1 phase (By similarity), Plays a role in lens fiber cell differentiation by regulating the expression of cell cycle regulator CDKN1A/p21Cip1 (By similarity), Binds to transcriptional repressor NR1D2 and relieves it of its inhibitory effect on the transcription of apolipoprotein APOC3 without affecting its DNA-binding activity (PubMed:17892483)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ZNHIT1 family", "domain_description": {"HIT-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVEKKTSVRSQDPGQRRVLDRAARQRRINRQLEALENDNFQDDPHAGLPQLGKRLPQFDDDADTGKKKKKTRGDHFKLRFRKNFQALLEEQNLSVAEGPNYLTACAGPPSRPQRPFCAVCGFPSPYTCVSCGARYCTVRCLGTHQETRCLKWTV", "length": 154, "molWeight": 17536, "crc64": "6A45F05249DC07A6", "md5": "DE09C6C914D2D534EE555D3708AAE4E2"}}
{"primaryAccession": "O43405", "text": "This is Cochlin protein, from Human, contains 550 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O43405", "organism_name": "Human", "protein_name": "Cochlin", "length": 550, "firstPublicDate": "2000-05-30", "FUNCTION": "Plays a role in the control of cell shape and motility in the trabecular meshwork", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSAAWIPALGLGVCLLLLPGPAGSEGAAPIAITCFTRGLDIRKEKADVLCPGGCPLEEFSVYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSASFTVTKGKSSTQEATGQAVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRDFLESQQ", "length": 550, "molWeight": 59483, "crc64": "74D7D51290098B30", "md5": "19157796CE72F854762C4DB7D1132B7E"}}
{"primaryAccession": "O43809", "text": "This is Cleavage and polyadenylation specificity factor subunit 5 protein, from Human, contains 227 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O43809", "organism_name": "Human", "protein_name": "Cleavage and polyadenylation specificity factor subunit 5", "length": 227, "firstPublicDate": "2006-02-07", "FUNCTION": "Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs (PubMed:9659921, PubMed:8626397, PubMed:14690600, PubMed:15937220, PubMed:17024186, PubMed:17098938, PubMed:29276085), CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals) (PubMed:9659921, PubMed:8626397, PubMed:14690600, PubMed:17024186), Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation (PubMed:17098938, PubMed:23187700, PubMed:29276085), The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs (PubMed:17098938, PubMed:20695905, PubMed:29276085), NUDT21/CPSF5 activates indirectly the mRNA 3'-processing machinery by recruiting CPSF6 and/or CPSF7 (PubMed:29276085), Binds to 5'-UGUA-3' elements localized upstream of pA signals that act as enhancers of pre-mRNA 3'-end processing (PubMed:8626397, PubMed:14690600, PubMed:15169763, PubMed:17024186, PubMed:22813749, PubMed:20479262), The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA (PubMed:20479262, PubMed:21295486), Plays a role in somatic cell fate transitions and pluripotency by regulating widespread changes in gene expression through an APA-dependent function (By similarity), Binds to chromatin (By similarity), Binds to, but does not hydrolyze mono- and di-adenosine nucleotides (PubMed:18445629)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Nudix hydrolase family, CPSF5 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN", "length": 227, "molWeight": 26227, "crc64": "D204243E57F1CCC5", "md5": "F51A91B82C7C64D16D852A603241D140"}}
{"primaryAccession": "O48538", "text": "This is Respiratory burst oxidase homolog protein F protein, from Mouse-ear cress, contains 944 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O48538", "organism_name": "Mouse-ear cress", "protein_name": "Respiratory burst oxidase homolog protein F", "length": 944, "firstPublicDate": "2008-01-15", "FUNCTION": "Calcium-dependent NADPH oxidase that generates superoxide, Generates reactive oxygen species (ROS) during incompatible interactions with pathogens and is important in the regulation of the hypersensitive response (HR), Involved in abscisic acid-induced stomatal closing and in UV-B and abscisic acid ROS-dependent signaling", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the RBOH (TC 5,B,1,3) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKPFSKNDRRRWSFDSVSAGKTAVGSASTSPGTEYSINGDQEFVEVTIDLQDDDTIVLRSVEPATAINVIGDISDDNTGIMTPVSISRSPTMKRTSSNRFRQFSQELKAEAVAKAKQLSQELKRFSWSRSFSGNLTTTSTAANQSGGAGGGLVNSALEARALRKQRAQLDRTRSSAQRALRGLRFISNKQKNVDGWNDVQSNFEKFEKNGYIYRSDFAQCIGMKDSKEFALELFDALSRRRRLKVEKINHDELYEYWSQINDESFDSRLQIFFDIVDKNEDGRITEEEVKEIIMLSASANKLSRLKEQAEEYAALIMEELDPERLGYIELWQLETLLLQKDTYLNYSQALSYTSQALSQNLQGLRGKSRIHRMSSDFVYIMQENWKRIWVLSLWIMIMIGLFLWKFFQYKQKDAFHVMGYCLLTAKGAAETLKFNMALILFPVCRNTITWLRSTRLSYFVPFDDNINFHKTIAGAIVVAVILHIGDHLACDFPRIVRATEYDYNRYLFHYFQTKQPTYFDLVKGPEGITGILMVILMIISFTLATRWFRRNLVKLPKPFDRLTGFNAFWYSHHLFVIVYILLILHGIFLYFAKPWYVRTTWMYLAVPVLLYGGERTLRYFRSGSYSVRLLKVAIYPGNVLTLQMSKPTQFRYKSGQYMFVQCPAVSPFEWHPFSITSAPEDDYISIHIRQLGDWTQELKRVFSEVCEPPVGGKSGLLRADETTKKSLPKLLIDGPYGAPAQDYRKYDVLLLVGLGIGATPFISILKDLLNNIVKMEEHADSISDFSRSSEYSTGSNGDTPRRKRILKTTNAYFYWVTREQGSFDWFKGVMNEVAELDQRGVIEMHNYLTSVYEEGDARSALITMVQALNHAKNGVDIVSGTRVRTHFARPNWKKVLTKLSSKHCNARIGVFYCGVPVLGKELSKLCNTFNQKGSTKFEFHKEHF", "length": 944, "molWeight": 108418, "crc64": "1ABAEC316AE80F9B", "md5": "92AE5CB5F8E17EED8C63C8C831E2E50D"}}
{"primaryAccession": "O48723", "text": "This is Patatin-like protein 2 protein, from Mouse-ear cress, contains 407 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O48723", "organism_name": "Mouse-ear cress", "protein_name": "Patatin-like protein 2", "length": 407, "firstPublicDate": "2014-03-19", "FUNCTION": "Possesses non-specific lipolytic acyl hydrolase (LAH) activity, Catalyzes the hydrolysis of the galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), and less efficiently the phoshpolipids phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG), phosphatidic acid (PA), phosphatidylserine (PS) and phosphatidylinositol (PI), Favors the release of fatty acid at the sn-1 position for PC or PE and the sn-2 position for PG, PA, PS and PI, Negatively affects disease resistance to the necrotic fungal pathogen Botrytis cinerea and the avirulent bacteria Pseudomonas syringae by promoting cell death and reducing the efficiency of the hypersensitive response, respectively, However, PLP2 contributes to resistance to cucumber mosaic virus (CMV), an obligate parasite inducing hypersensitive response, May negatively regulate oxylipin production, possibly via participating in membrane repair that includes removal of oxidatively modified lipids", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the patatin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQMDSPKSPLQPPTYGNLVTILSIDGGGIRGLIPAVILGFLESELQKLDGEEARLADYFDVIAGTSTGGLVTAMLTAPNKEGRPLFAASEIKDFYLEQCPKIFPQDHFPFSAAKKLVKSLTGPKYDGKYLHQLIHAKLGDTKLSQTLTNVVIPTFDIKHLQPTIFSSYEVKNHPLKDATLADIAISTSAAPTYLPAHFFKVEDLNGNAKEYNLIDGGVAANNPALLAIGEVTNEISGGSSDFFPIRPNDYGRFLVLSLGTGNHKAEEKFNAKEVAGWGLLNWLTHDNSTPIIDAFSQASSDMVDFHLSAVFRALHSEANYIRIQDDTLTGDAASVDIATVENLDILAKTGDELLKKPVARVNLDSGCNENAYETTNEHALIKLAGILSKEKKIRDIRSPHAKAPIRI", "length": 407, "molWeight": 44239, "crc64": "AC113497DFB647C4", "md5": "F247E0D25D6E35EA7B09F22ED0A730EE"}}
{"primaryAccession": "O48814", "text": "This is Serine/threonine-protein kinase BIK1 protein, from Mouse-ear cress, contains 395 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O48814", "organism_name": "Mouse-ear cress", "protein_name": "Serine/threonine-protein kinase BIK1", "length": 395, "firstPublicDate": "2007-11-13", "FUNCTION": "(Microbial infection) Xanthomonas campestris effector AvrAC/XopAC-mediated uridylylation prevents activation by phosphorylation at the same residues, thus affecting immune responses and reducing defense responses toward X,campestris, mediating avrAC/XopAC virulence functions", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGSCFSSRVKADIFHNGKSSDLYGLSLSSRKSSSTVAAAQKTEGEILSSTPVKSFTFNELKLATRNFRPDSVIGEGGFGCVFKGWLDESTLTPTKPGTGLVIAVKKLNQEGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEHRLLVYEFMQKGSLENHLFRRGAYFKPLPWFLRVNVALDAAKGLAFLHSDPVKVIYRDIKASNILLDADYNAKLSDFGLARDGPMGDLSYVSTRVMGTYGYAAPEYMSSGHLNARSDVYSFGVLLLEILSGKRALDHNRPAKEENLVDWARPYLTSKRKVLLIVDNRLDTQYLPEEAVRMASVAVQCLSFEPKSRPTMDQVVRALQQLQDNLGKPSQTNPVKDTKKLGFKTGTTKSSEKRFTQKPFGRHLV", "length": 395, "molWeight": 44097, "crc64": "4C06B1FD01889440", "md5": "68096362C50E905BC1C8AAB4A378FDA5"}}
{"primaryAccession": "O49397", "text": "This is Two-component response regulator ARR10 protein, from Mouse-ear cress, contains 552 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O49397", "organism_name": "Mouse-ear cress", "protein_name": "Two-component response regulator ARR10", "length": 552, "firstPublicDate": "2003-10-31", "FUNCTION": "Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3', Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system, Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes, Could directly activate some type-A response regulators in response to cytokinins", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ARR family, Type-B subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTMEQEIEVLDQFPVGMRVLAVDDDQTCLRILQTLLQRCQYHVTTTNQAQTALELLRENKNKFDLVISDVDMPDMDGFKLLELVGLEMDLPVIMLSAHSDPKYVMKGVKHGACDYLLKPVRIEELKNIWQHVVRKSKLKKNKSNVSNGSGNCDKANRKRKEQYEEEEEEERGNDNDDPTAQKKPRVLWTHELHNKFLAAVDHLGVERAVPKKILDLMNVDKLTRENVASHLQKFRVALKKVSDDAIQQANRAAIDSHFMQMNSQKGLGGFYHHHRGIPVGSGQFHGGTTMMRHYSSNRNLGRLNSLGAGMFQPVSSSFPRNHNDGGNILQGLPLEELQINNNINRAFPSFTSQQNSPMVAPSNLLLLEGNPQSSSLPSNPGFSPHFEISKRLEHWSNAALSTNIPQSDVHSKPDTLEWNAFCDSASPLVNPNLDTNPASLCRNTGFGSTNAAQTDFFYPLQMNQQPANNSGPVTEAQLFRSSNPNEGLLMGQQKLQSGLMASDAGSLDDIVNSLMTQEQSQSDFSEGDWDLDGLAHSEHAYEKLHFPFSLSA", "length": 552, "molWeight": 61652, "crc64": "B419363AC09E9555", "md5": "D3E8D314149CE8594B5DD0A834D196EE"}}
{"primaryAccession": "O49432", "text": "This is Polygalacturonase QRT3 protein, from Mouse-ear cress, contains 481 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O49432", "organism_name": "Mouse-ear cress", "protein_name": "Polygalacturonase QRT3", "length": 481, "firstPublicDate": "2009-05-05", "FUNCTION": "Polygalacturonase required for degrading the pollen mother cell wall during microspore development", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 28 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MELRKSQVAMPVFLAIMSLMVSQVVFAEKDSGSMSPHDRALAEMQALKASLVRRNLPALVSPPPTPPQAVPGPRVYQVISYGADPTGKLDSTDAILKAMEEAFDGPNHGVLMQGINDLGGARIDLQGGSYLISRPLRFPSAGAGNLLISGGTLRASNDFPVDRYLIELKDESSKLQYIFEYITLRDLLIDCNYRGGAIAVINSLRTSIDNCYITRFGDTNGILVKSGHETYIRNSFLGQHITAGGDRGERSFSGTAINLMGNDNAVTDTVIFSARIGVMVSGQANLLSGVHCYNKATGFGGTGIYLRLPGLTQNRIVNSYLDYTGIVAEDPVQLQISGTFFLGDAFILLKSIAGYIRGVSIVDNMFSGSGHGVQIVQLDQRNTAFDDVGQVVVDRNSVNGMVEKSTVARGSVDGNGTSWTVDFNPVLLFPDLINHVQYTLVASEAGVFPLHALRNVSDNRVVVETNAPVTGTVYVTVNQGV", "length": 481, "molWeight": 51659, "crc64": "9299F16297364257", "md5": "16B0A3CDC95E16892112C699B12DA461"}}
{"primaryAccession": "O49523", "text": "This is Phospholipase A1-IIgamma protein, from Mouse-ear cress, contains 419 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O49523", "organism_name": "Mouse-ear cress", "protein_name": "Phospholipase A1-IIgamma", "length": 419, "firstPublicDate": "2011-05-31", "FUNCTION": "Acylhydrolase that catalyzes the hydrolysis of 1,3-diacylglycerol (1,3-DAG) and 1-monoacylglycerol (1-MAG) at the sn-1 position, High activity toward 1,3-DAG and 1-MAG, but low activity toward 1,2-diacylglycerol (1,2-DAG) and 1-lysophosphatidylcholine (1-LPC), and no activity toward phosphatidylcholine (PC), monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG), triacylglycerol (TAG) and 2-monoacylglycerol (2-MAG), May be involved in the negative regulation of seedling establishment by inhibiting the breakdown, beta-oxidation and mobilization of seed storage oils", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKRKKKEEEEEKLIVTREFAKRWRDLSGQNHWKGMLQPLDQDLREYIIHYGEMAQAGYDTFNINTESQFAGASIYSRKDFFAKVGLEIAHPYTKYKVTKFIYATSDIHVPESFLLFPISREGWSKESNWMGYVAVTDDQGTALLGRRDIVVSWRGSVQPLEWVEDFEFGLVNAIKIFGERNDQVQIHQGWYSIYMSQDERSPFTKTNARDQVLREVGRLLEKYKDEEVSITICGHSLGAALATLSATDIVANGYNRPKSRPDKSCPVTAFVFASPRVGDSDFRKLFSGLEDIRVLRTRNLPDVIPIYPPIGYSEVGDEFPIDTRKSPYMKSPGNLATFHCLEGYLHGVAGTQGTNKADLFRLDVERAIGLVNKSVDGLKDECMVPGKWRVLKNKGMAQQDDGSWELVDHEIDDNEDLDF", "length": 419, "molWeight": 47792, "crc64": "3B2B13089146482C", "md5": "821B4F44735982FE822802B528C1EE09"}}
{"primaryAccession": "O49597", "text": "This is High mobility group B protein 5 protein, from Mouse-ear cress, contains 125 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O49597", "organism_name": "Mouse-ear cress", "protein_name": "High mobility group B protein 5", "length": 125, "firstPublicDate": "2010-11-02", "FUNCTION": "Binds preferentially double-stranded DNA, Confers resistance to salt and drought stresses", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the HMGB family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKDNQTEVESRSTDDRLKVRGNKVGKKTKDPNRPKKPPSPFFVFLDDFRKEFNLANPDNKSVGNVGRAAGKKWKTMTEEERAPFVAKSQSKKTEYAVTMQQYNMELANGNKTTGDDEKQEKAADD", "length": 125, "molWeight": 14203, "crc64": "9C6C268C4D3A0FDF", "md5": "2A8390C9362779A210F45CAE0FCFA8E3"}}
{"primaryAccession": "O49782", "text": "This is Transcription factor MYB51 protein, from Mouse-ear cress, contains 352 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O49782", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor MYB51", "length": 352, "firstPublicDate": "2013-12-11", "FUNCTION": "Transcription factor positively regulating indolic glucosinolate biosynthetic pathway genes", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVRTPCCKAELGLKKGAWTPEEDQKLLSYLNRHGEGGWRTLPEKAGLKRCGKSCRLRWANYLRPDIKRGEFTEDEERSIISLHALHGNKWSAIARGLPGRTDNEIKNYWNTHIKKRLIKKGIDPVTHKGITSGTDKSENLPEKQNVNLTTSDHDLDNDKAKKNNKNFGLSSASFLNKVANRFGKRINQSVLSEIIGSGGPLASTSHTTNTTTTSVSVDSESVKSTSSSFAPTSNLLCHGTVATTPVSSNFDVDGNVNLTCSSSTFSDSSVNNPLMYCDNFVGNNNVDDEDTIGFSTFLNDEDFMMLEESCVENTAFMKELTRFLHEDENDVVDVTPVYERQDLFDEIDNYFG", "length": 352, "molWeight": 39154, "crc64": "ABD3751C93516AA4", "md5": "2615E5C497E936FB9C91BCAD8370222A"}}
{"primaryAccession": "O54751", "text": "This is Cone-rod homeobox protein protein, from Mouse, contains 299 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O54751", "organism_name": "Mouse", "protein_name": "Cone-rod homeobox protein", "length": 299, "firstPublicDate": "1998-07-15", "FUNCTION": "Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes, Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription, Essential for the maintenance of mammalian photoreceptors", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the paired homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMAYMNPGPHYSVNALALSGPNVDLMHQAVPYSSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGAQTKARPAKRKAGTSPRPSTDVCTDPLGISDSYSPSLPGPSGSPTTAVATVSIWSPASEAPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYASPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSGQSYSTYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL", "length": 299, "molWeight": 32374, "crc64": "4FE2C27D8070B524", "md5": "40B260E55BDEABB44D549D89A2AFF684"}}
{"primaryAccession": "O57437", "text": "This is Deleted in azoospermia-like-A protein, from African clawed frog, contains 286 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O57437", "organism_name": "African clawed frog", "protein_name": "Deleted in azoospermia-like-A", "length": 286, "firstPublicDate": "2006-09-05", "FUNCTION": "RNA-binding protein that is required for primordial germ cell (PGC) differentiation and indirectly necessary for the migration of PGCs through the endoderm, May promote meiotic cell division during spermatogenesis, Shows a preference for G- and U-rich RNAs and probably binds the 3'-UTR of target mRNAs, Stimulates the initiation of translation of mRNAs through the recruitment of poly(A)-binding proteins (PABPs)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the RRM DAZ family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSGKEESSNYAATAEEEAVNQGFVLPEGEIMPNTVFVGGIDITMDEIEIRDFFTRFGNVKEVKIITDRTGVSKGYGFISFSDEVDVQKIVKSQISFHGKKLKLGPAIRKICTYVQPRPVVLSHPTPFHHAWNNQNADSYIQHSPIVSPITQYVQACPYPSSPPMAIQQIPVGCQQPGYFQVSPQWPADQRSYMFPTPAFTFNYHCCDMDPNGGEPIPREYPIDQTVSASGANPQKRYVEMSTQTIVSCLFDPANKFHSFVSQEDYLKDNRVHHLRRRESVIKRVSK", "length": 286, "molWeight": 32298, "crc64": "C5BA0FA29D0FD65E", "md5": "9540FE2C35BB687C9613B5DBA44E2617"}}
{"primaryAccession": "O59676", "text": "This is PWWP domain-containing protein 1 protein, from Fission yeast, contains 359 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59676", "organism_name": "Fission yeast", "protein_name": "PWWP domain-containing protein 1", "length": 359, "firstPublicDate": "2007-09-11", "FUNCTION": "Necessary for DNA damage checkpoint activation, Required for the association of set9 with chromatin and subsequent methylation of H4K20, Associates with H4K20me1 to increase the concentration of set9 on chromatin to perform H4K20me3, H4K20me3 is mainly enriched at heterochromatin and is required for proper heterochromatin assembly", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNNARTNAKRRRLSSKQGGLSISEGKESNIPSVVEESKDNLEQASADDRLNFGDRILVKAPGYPWWPALLLRRKETKDSLNTNSSFNVLYKVLFFPDFNFAWVKRNSVKPLLDSEIAKFLGSSKRKSKELIEAYEASKTPPDLKEESSTDEEMDSLSAAEEKPNFLQKRKYHWETSLDESDAESISSGSLMSITSISEMYGPTVASTSRSSTQLSDQRYPLSSNFDHRGEAKGKGKQPLKNPQERGRISPSSPLNDQTKALMQRLLFFRHKLQKAFLSPDHLIVEEDFYNASKYLNAISDIPFLNYELITSTKLAKVLKRIAFLEHLENDELYDIRQKCKNLLYSWAMFLPNEPSIKGM", "length": 359, "molWeight": 40923, "crc64": "A892EE06E5F7DB2A", "md5": "5012C48AB945DCDBC32FC512D460CDCB"}}
{"primaryAccession": "O59755", "text": "This is Spindle pole body-associated protein cut12 protein, from Fission yeast, contains 548 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59755", "organism_name": "Fission yeast", "protein_name": "Spindle pole body-associated protein cut12", "length": 548, "firstPublicDate": "2002-12-06", "FUNCTION": "Required for bipolar spindle formation, May act as a regulator of the p34cdc2/cyclin B kinase, Required for full activation of the plo1 kinase, However, in cut12,1 cells at restrictive temperature the H1 kinase does rise concomitant with entry into mitosis, indicating that cut12 is not required for activation of p34cdc2/cyclin B, The cut12,s11 allele may promote cdc2-independent phosphorylation of SPB proteins thereby overcoming the requirement for cdc25 in cell cycle progression", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSETLNTPPTYAWVLKAFSSKLAGTVTKPVTKMSSYIEDAESDAELPQDAKEDLRPTETLTPLKSKAAQNGILKTPGTLQIKKTVNFKDISKDAATWNRPTKNNFLFTRLDDENPLMGHEEFKSPLLQSTPKPNINNPDNENKSKHDEFDNRYNININESYKNETKSNQRLGEDVPSKKKYPHSMDAEISKFKWDSNNNNDWSSLMKDCFRDVVNNNRKMKEIIKDVMIDTSQAFPSESLDEPDYTINLDAPRSSSGKYWKQKFSMLDSAHSDLELELTSIRERLESLILEKQEEINFWKQRCRALETEKIHNHQGQQSKYKGKEFVGNRFSQMRELYTAKPSPITTKVVSRPSQSDVREPQEQVPSKNLHRGADMSHLAAQMLTHSSKKSHTTNLIPSEGIISSTPISAASKVRMNLMQSNQTPTPAPFSIAAKKSHLPSKLSFPQDGGSLSSATTLQQLPKARVTPNVLSSLSSNLGKTNPTSVYQSKANVTTSADVEKPQVKVATSSRVDYDLKSPNQRTANAKKRLEERRRRRKLKLQELQLNS", "length": 548, "molWeight": 61958, "crc64": "01FF6BC68D577A54", "md5": "A78A6B5F54E6BCDE5B32B1B4A063B484"}}
{"primaryAccession": "O59893", "text": "This is Acetylxylan esterase 2 protein, from Soft rot fungus, contains 234 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59893", "organism_name": "Soft rot fungus", "protein_name": "Acetylxylan esterase 2", "length": 234, "firstPublicDate": "2006-05-16", "FUNCTION": "Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the cutinase family, Acetylxylan esterase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MHSKFFAASLLGLGAAAIPLEGVMEKRSCPAIHVFGARETTASPGYGSSSTVVNGVLSAYPGSTAEAINYPACGGQSSCGGASYSSSVAQGIAAVASAVNSFNSQCPSTKIVLVGYSQGGEIMDVALCGGGDPNQGYTNTAVQLSSSAVNMVKAAIFMGDPMFRAGLSYEVGTCAAGGFDQRPAGFSCPSAAKIKSYCDASDPYCCNGSNAATHQGYGSEYGSQALAFVKSKLG", "length": 234, "molWeight": 23478, "crc64": "C033B3DA4E7BB6E1", "md5": "4BCE196D2C0322913E711F3B00568E35"}}
{"primaryAccession": "O60237", "text": "This is Protein phosphatase 1 regulatory subunit 12B protein, from Human, contains 982 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60237", "organism_name": "Human", "protein_name": "Protein phosphatase 1 regulatory subunit 12B", "length": 982, "firstPublicDate": "2004-01-16", "FUNCTION": "Regulates myosin phosphatase activity, Augments Ca(2+) sensitivity of the contractile apparatus", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLELLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQEMEEENKESSSSSSEEEEGEDEASESETEKEADKKPEAFVNHSNSESKSSITEQIPAPAQNTFSASSARRFSSGLFNKPEEPKDESPSSWRLGLRKTGSHNMLSEVANSREPIRDRGSSIYRSSSSPRISALLDNKDKERENKSYISSLAPRKLNSTSDIEEKENRESAVNLVRSGSYTRQLWRDEAKGNEIPQTIAPSTYVSTYLKRTPHKSQADTTAEKTADNVSSSTPLCVITNRPLPSTANGVTATPVLSITGTDSSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERTFSRSRAERQAQEQPREKPTDTEGLEGSPEKHEPSAVPATEAGEGQQPWGRSLDEEPICHRLRCPAQPDKPTTPASPSTSRPSLYTSSHLLWTNRFSVPDSESSETTTNTTTAKEMDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 982, "molWeight": 110404, "crc64": "A6EBB6AD4C61DD3B", "md5": "1B76FDAE8270369BD8F33030DFC00A2A"}}
{"primaryAccession": "O60477", "text": "This is BMP/retinoic acid-inducible neural-specific protein 1 protein, from Human, contains 761 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60477", "organism_name": "Human", "protein_name": "BMP/retinoic acid-inducible neural-specific protein 1", "length": 761, "firstPublicDate": "2006-01-24", "FUNCTION": "Plays a role in neurogenesis and brain development (By similarity), May suppress cell cycle progression in postmitotic neurons by inhibiting G1/S transition (PubMed:11420708)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the BRINP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNWRFVELLYFLFIWGRISVQPSHQEPAGTDQHVSKEFDWLISDRGPFHHSRSYLSFVERHRQGFTTRYKIYREFARWKVRNTAIERRDLVRHPVPLMPEFQRSIRLLGRRPTTQQFIDTIIKKYGTHLLISATLGGEEALTMYMDKSRLDRKSGNATQSVEALHQLASSYFVDRDGTMRRLHEIQISTGAIKVTETRTGPLGCNSYDNLDSVSSVLLQSTESKLHLQGLQIIFPQYLQEKFVQSALSYIMCNGEGEYLCQNSQCRCQCAEEFPQCNCPITDIQIMEYTLANMAKSWAEAYKDLENSDEFKSFMKRLPSNHFLTIGSIHQHWGNDWDLQNRYKLLQSATEAQRQKIQRTARKLFGLSVRCRHNPNHQLPRERTIQQWLARVQSLLYCNENGFWGTFLESQRSCVCHGSTTLCQRPIPCVIGGNNSCAMCSLANISLCGSCNKGYKLYRGRCEPQNVDSERSEQFISFETDLDFQDLELKYLLQKMDSRLYVHTTFISNEIRLDTFFDPRWRKRMSLTLKSNKNRMDFIHMVIGMSMRICQMRNSSLDPMFFVYVNPFSGSHSEGWNMPFGEFGYPRWEKIRLQNSQCYNWTLLLGNRWKTFFETVHIYLRSRTRLPTLLRNETGQGPVDLSDPSKRQFYIKISDVQVFGYSLRFNADLLRSAVQQVNQSYTQGGQFYSSSSVMLLLLDIRDRINRLAPPVAPGKPQLDLFSCMLKHRLKLTNSEIIRVNHALDLYNTEILKQSDQMTAKLC", "length": 761, "molWeight": 88760, "crc64": "16FF47082FD52252", "md5": "7EB7CB8070C415BA22F7374FFC5EC133"}}
{"primaryAccession": "O60478", "text": "This is Integral membrane protein GPR137B protein, from Human, contains 399 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60478", "organism_name": "Human", "protein_name": "Integral membrane protein GPR137B", "length": 399, "firstPublicDate": "2003-11-07", "FUNCTION": "Acts also as a negative regulator of osteoclast activity (By similarity), Involved in interleukin-4-induced M2 macrophage polarization (By similarity)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the GPR137 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRPERPRPRGSAPGPMETPPWDPARNDSLPPTLTPAVPPYVKLGLTVVYTVFYALLFVFIYVQLWLVLRYRHKRLSYQSVFLFLCLFWASLRTVLFSFYFKDFVAANSLSPFVFWLLYCFPVCLQFFTLTLMNLYFTQVIFKAKSKYSPELLKYRLPLYLASLFISLVFLLVNLTCAVLVKTGNWERKVIVSVRVAINDTLFVLCAVSLSICLYKISKMSLANIYLESKGSSVCQVTAIGVTVILLYTSRACYNLFILSFSQNKSVHSFDYDWYNVSDQADLKNQLGDAGYVLFGVVLFVWELLPTTLVVYFFRVRNPTKDLTNPGMVPSHGFSPRSYFFDNPRRYDSDDDLAWNIAPQGLQGGFAPDYYDWGQQTNSFLAQAGTLQDSTLDPDKPSLG", "length": 399, "molWeight": 45599, "crc64": "FE788D618A590604", "md5": "A8FFF84534E729FD956EFE61CC789267"}}
{"primaryAccession": "O60508", "text": "This is Pre-mRNA-processing factor 17 protein, from Human, contains 579 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60508", "organism_name": "Human", "protein_name": "Pre-mRNA-processing factor 17", "length": 579, "firstPublicDate": "2001-09-26", "FUNCTION": "Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:33220177), Plays an important role in embryonic brain development; this function does not require proline isomerization (PubMed:33220177)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSAAIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLAVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD", "length": 579, "molWeight": 65521, "crc64": "1DE2BAA6F03FF16D", "md5": "4FF7BCD00181BEEC2F2D3E27683322FE"}}
{"primaryAccession": "O60635", "text": "This is Tetraspanin-1 protein, from Human, contains 241 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60635", "organism_name": "Human", "protein_name": "Tetraspanin-1", "length": 241, "firstPublicDate": "2000-12-01", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the tetraspanin (TM4SF) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNVTNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNLQ", "length": 241, "molWeight": 26301, "crc64": "AF938AD7147CB884", "md5": "307C7BDDE96EE5473917076FFD04B179"}}
{"primaryAccession": "O60858", "text": "This is E3 ubiquitin-protein ligase TRIM13 protein, from Human, contains 407 amino acids, has 1 RING-type Zinc finger, has 1 B box-type Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [10, 58], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [89, 131], "description": "B box-type", "keyword_description": "Zinc finger", "textural_description": "B box-type Zinc finger"}], "meta_data": {"primaryAccession": "O60858", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase TRIM13", "length": 407, "firstPublicDate": "2000-12-01", "FUNCTION": "Endoplasmic reticulum (ER) membrane anchored E3 ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD), This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins, Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation, Regulates ER stress-induced autophagy, and may act as a tumor suppressor (PubMed:22178386), Also plays a role in innate immune response by stimulating NF-kappa-B activity in the TLR2 signaling pathway, Ubiquitinates TRAF6 via the 'Lys-29'-linked polyubiquitination chain resulting in NF-kappa-B activation (PubMed:28087809), Participates as well in T-cell receptor-mediated NF-kappa-B activation (PubMed:25088585), In the presence of TNF, modulates the IKK complex by regulating IKBKG/NEMO ubiquitination leading to the repression of NF-kappa-B (PubMed:25152375)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the TRIM/RBCC family", "domain_description": {"RING-type Zinc finger": 1, "B box-type Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL", "length": 407, "molWeight": 46988, "crc64": "94B624345124AEBF", "md5": "C2473560C9C7660C81751B203D97B8B5"}}
{"primaryAccession": "O60896", "text": "This is Receptor activity-modifying protein 3 protein, from Human, contains 148 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60896", "organism_name": "Human", "protein_name": "Receptor activity-modifying protein 3", "length": 148, "firstPublicDate": "2000-12-01", "FUNCTION": "Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner, Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane, Acts as a receptor for adrenomedullin (AM) together with CALCRL", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the RAMP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "METGALRRPQLLPLLLLLCGGCPRAGGCNETGMLERLPLCGKAFADMMGKVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEVLIPLIVIPVVLTVAMAGLVVWRSKRTDTLL", "length": 148, "molWeight": 16518, "crc64": "EEEE312496EF513C", "md5": "EC921B6928EE3A87DB8794525C3E38B4"}}
{"primaryAccession": "O61577", "text": "This is Katanin p60 ATPase-containing subunit A1 protein, from Purple sea urchin, contains 516 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O61577", "organism_name": "Purple sea urchin", "protein_name": "Katanin p60 ATPase-containing subunit A1", "length": 516, "firstPublicDate": "2005-03-01", "FUNCTION": "Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner, Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation, In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the AAA ATPase family, Katanin p60 subunit A1 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSVDEICENTKMGREYALLGNYETSLVYYQGVLQQIQKLLTSVHEPQRKHQWQTIRQELSQEYEHVKNITKTLNGFKSEPAAPEPAPNHRAAPFSHHQHAAKPAAAEPARDPDVWPPPTPVDHRPSPPYQRAARKDPPRRSEPSKPANRAPGNDRGGRGPSDRRGDARSGGGGRGGARGSDKDKNRGGKSDKDKKAPSGEEGDEKKFDPAGYDKDLVENLERDIVQRNPNVHWADIAGLTEAKRLLEEAVVLPLWMPDYFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSASLTSKYHGESEKLVRLLFEMARFYAPSTIFIDEIDSICSKRGTGSEHEASRRVKSELLIQMDGVSGPSAGEESSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPEIDGREQLLRINLKEVPLADDIDLKSIAEKMDGYSGADITNVCRDASMMAMRRRIQGLRPEEIRHIPKEELNQPSTPADFLLALQKVSKSVGKEDLVKYMAWMEEFGSV", "length": 516, "molWeight": 57593, "crc64": "A4E573AA643EF57F", "md5": "FC09E0037F02C947B6B3470E4E1C8E10"}}
{"primaryAccession": "O61661", "text": "This is Serine/threonine-protein kinase grp protein, from Fruit fly, contains 512 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O61661", "organism_name": "Fruit fly", "protein_name": "Serine/threonine-protein kinase grp", "length": 512, "firstPublicDate": "2003-10-10", "FUNCTION": "Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA, May also negatively regulate cell cycle progression during unperturbed cell cycles, May phosphorylate the CDC25 phosphatase stg, which promotes its degradation, This results in increased inhibitory tyrosine phosphorylation of Cdk1-cyclin complexes and consequent inhibition of cell cycle progression", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAATLTEAGTGPAATREFVEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKMLQDKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVLQKAYHAQPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATSPGTRLTLEKTLDHKWCNMQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPMPTMRSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQNYFQRLVRRMTRFFVTTRWDDTIKRLVGTIERLGGYTCKFGDDGVVTVSTVDRNKLRLVFKAHIIEMDGKILVDCRLSKGCGLEFKRRFIKIKNALEDIVLKGPTTWPIAIATNSVP", "length": 512, "molWeight": 57833, "crc64": "504CAB3C0B642EA0", "md5": "CA5585C8FC2C0192D3194B9D1D073C1B"}}
{"primaryAccession": "O64425", "text": "This is E3 ubiquitin-protein ligase RMA1 protein, from Mouse-ear cress, contains 249 amino acids, has 1 RING-type Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [48, 97], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "O64425", "organism_name": "Mouse-ear cress", "protein_name": "E3 ubiquitin-protein ligase RMA1", "length": 249, "firstPublicDate": "2010-07-13", "FUNCTION": "E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of aquaporin PIP2-1, Forms a ubiquitin ligase complex in cooperation with the E2 enzymes UCB8/UCB10", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MALDQSFEDAALLGELYGEGAFCFKSKKPEPITVSVPSDDTDDSNFDCNICLDSVQEPVVTLCGHLFCWPCIHKWLDVQSFSTSDEYQRHRQCPVCKSKVSHSTLVPLYGRGRCTTQEEGKNSVPKRPVGPVYRLEMPNSPYASTDLRLSQRVHFNSPQEGYYPVSGVMSSNSLSYSAVLDPVMVMVGEMVATRLFGTRVMDRFAYPDTYNLAGTSGPRMRRRIMQADKSLGRIFFFFMCCVVLCLLLF", "length": 249, "molWeight": 28012, "crc64": "0477C433BA96DE4D", "md5": "3B1DB0F5235D8B2DB06B91834C1AC5A2"}}
{"primaryAccession": "O65312", "text": "This is Histone-lysine N-methyltransferase MEDEA protein, from Mouse-ear cress, contains 689 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O65312", "organism_name": "Mouse-ear cress", "protein_name": "Histone-lysine N-methyltransferase MEDEA", "length": 689, "firstPublicDate": "2003-05-16", "FUNCTION": "Polycomb group (PcG) protein, Catalytic subunit of some PcG multiprotein complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target genes, Required to prevent the proliferation of the central cell of the female gametophyte by repressing target genes before fertilization, After fertilization, it probably also regulates the embryo and endosperm proliferation and anteroposterior organization during seed development, PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development, PcG proteins are not required to initiate repression, but to maintain it during later stages of development, Interacts with the promoter and repress the transcription of genes such as PHE1 and PHE2, that are paternally active and maternally silenced genes", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, EZ subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEKENHEDDGEGLPPELNQIKEQIEKERFLHIKRKFELRYIPSVATHASHHQSFDLNQPAAEDDNGGDNKSLLSRMQNPLRHFSASSDYNSYEDQGYVLDEDQDYALEEDVPLFLDEDVPLLPSVKLPIVEKLPRSITWVFTKSSQLMAESDSVIGKRQIYYLNGEALELSSEEDEEDEEEDEEEIKKEKCEFSEDVDRFIWTVGQDYGLDDLVVRRALAKYLEVDVSDILERYNELKLKNDGTAGEASDLTSKTITTAFQDFADRRHCRRCMIFDCHMHEKYEPESRSSEDKSSLFEDEDRQPCSEHCYLKVRSVTEADHVMDNDNSISNKIVVSDPNNTMWTPVEKDLYLKGIEIFGRNSCDVALNILRGLKTCLEIYNYMREQDQCTMSLDLNKTTQRHNQVTKKVSRKSSRSVRKKSRLRKYARYPPALKKTTSGEAKFYKHYTPCTCKSKCGQQCPCLTHENCCEKYCGCSKDCNNRFGGCNCAIGQCTNRQCPCFAANRECDPDLCRSCPLSCGDGTLGETPVQIQCKNMQFLLQTNKKILIGKSDVHGWGAFTWDSLKKNEYLGEYTGELITHDEANERGRIEDRIGSSYLFTLNDQLEIDARRKGNEFKFLNHSARPNCYAKLMIVRGDQRIGLFAERAIEEGEELFFDYCYGPEHADWSRGREPRKTGASKRSKEARPAR", "length": 689, "molWeight": 79310, "crc64": "2103D06ACD589CDF", "md5": "D7B48CA0DB1250EB4534F9AEED7A3E83"}}
{"primaryAccession": "O65375", "text": "This is Leucine-rich repeat extensin-like protein 1 protein, from Mouse-ear cress, contains 744 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O65375", "organism_name": "Mouse-ear cress", "protein_name": "Leucine-rich repeat extensin-like protein 1", "length": 744, "firstPublicDate": "2010-07-13", "FUNCTION": "Modulates cell morphogenesis by regulating cell wall formation and assembly, and/or growth polarization, Together with LRX2, component of the extracellular mechanism regulating root hair morphogenesis and elongation", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLFPPLRSLFLFTLLLSSVCFLQIKADHDDESDLGSDIKVDKRLKFENPKLRQAYIALQSWKKAIFSDPFNFTANWNGSDVCSYNGIYCAPSPSYPKTRVVAGIDLNHADMAGYLASELGLLSDLALFHINSNRFCGEVPLTFNRMKLLYELDLSNNRFVGKFPKVVLSLPSLKFLDLRYNEFEGKIPSKLFDRELDAIFLNHNRFRFGIPKNMGNSPVSALVLADNNLGGCIPGSIGQMGKTLNELILSNDNLTGCLPPQIGNLKKVTVFDITSNRLQGPLPSSVGNMKSLEELHVANNAFTGVIPPSICQLSNLENFTYSSNYFSGRPPICAASLLADIVVNGTMNCITGLARQRSDKQCSSLLARPVDCSKFGCYNIFSPPPPTFKMSPEVRTLPPPIYVYSSPPPPPSSKMSPTVRAYSPPPPPSSKMSPSVRAYSPPPPPYSKMSPSVRAYPPPPPPSPSPPPPYVYSSPPPPYVYSSPPPPPYVYSSPPPPPYVYSSPPPPYVYSSPPPPYVYSSPPPPPPSPPPPCPESSPPPPVVYYAPVTQSPPPPSPVYYPPVTQSPPPPSPVYYPPVTNSPPPPSPVYYPPVTYSPPPPSPVYYPQVTPSPPPPSPLYYPPVTPSPPPPSPVYYPPVTPSPPPPSPVYYPPVTPSPPPPSPVYYPSETQSPPPPTEYYYSPSQSPPPTKACKEGHPPQATPSYEPPPEYSYSSSPPPPSPTSYFPPMPSVSYDASPPPPPSYY", "length": 744, "molWeight": 80994, "crc64": "3C75174DBBB91F6F", "md5": "C9C21B05F18FF2245A02D9A0E0C082EE"}}
{"primaryAccession": "O70237", "text": "This is Zinc finger protein Gfi-1b protein, from Mouse, contains 330 amino acids, has 6 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [163, 186], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [192, 214], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [220, 242], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [248, 270], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [276, 298], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [304, 327], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "O70237", "organism_name": "Mouse", "protein_name": "Zinc finger protein Gfi-1b", "length": 330, "firstPublicDate": "2007-10-02", "FUNCTION": "Essential proto-oncogenic transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages, Component of a RCOR-GFI-KDM1A-HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation, Transcriptional repressor or activator depending on both promoter and cell type context; represses promoter activity of SOCS1 and SOCS3 and thus, may regulate cytokine signaling pathways, Cooperates with GATA1 to repress target gene transcription, such as the apoptosis regulator BCL2L1; GFI1B silencing in leukemic cell lines markedly increase apoptosis rate, Inhibits down-regulation of MYC and MYB as well as the cyclin-dependent kinase inhibitor CDKN1A/P21WAF1 in IL6-treated myelomonocytic cells, Represses expression of GATA3 in T-cell lymphomas and inhibits GATA1-mediated transcription; as GATA1 also mediates erythroid GFI1B transcription, both GATA1 and GFI1B participate in a feedback regulatory pathway controlling the expression of GFI1B gene in erythroid cells, Suppresses GATA1-mediated stimulation of GFI1B promoter through protein interaction, Binds to gamma-satellite DNA and to its own promoter, auto-repressing its own expression, Alters histone methylation by recruiting histone methyltransferase to target genes promoters, Plays a role in heterochromatin formation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 6}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPRSFLVKSKKAHTYHQPRAQGDELVWPPAVIPVAKEHSQSASPLLSTPLPSQTLDWNTIKQEREMLLNQSLPKMASAPEGPLVTPQPQDGESPLSESPPFYKPSFSWDTLASSYSHSYTQTPSTMQSAFLERSVRLYGSPLVPSTESPLDFRLRYSPGMDTYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDVCGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHNLK", "length": 330, "molWeight": 37443, "crc64": "6194D1972112E6FC", "md5": "E7C95F3F81D059C202C132050FFE5406"}}
{"primaryAccession": "O70491", "text": "This is Receptor for retinol uptake STRA6 protein, from Mouse, contains 670 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O70491", "organism_name": "Mouse", "protein_name": "Receptor for retinol uptake STRA6", "length": 670, "firstPublicDate": "2007-11-13", "FUNCTION": "Functions as retinol transporter (PubMed:23839944, PubMed:24852372), Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1, Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A (By similarity), Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin (PubMed:21368206, PubMed:23839944), Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid and 11-cis-retinal (PubMed:22467576, PubMed:24852372), STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency (PubMed:22467576, PubMed:23839944, PubMed:24852372), Does not transport retinoic acid (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MESQASENGSQTSSGVTDDYSSWYIEEPLGAEEVQPEGVIPLCQLTAPPALLHACLASLSFLVLLLLALLVRRRRLWPRCGHRGLGLPSPVDFLAGDLSWTVPAAVFVVLFSNLCLLLPDENPLPFLNLTAASSPDGEMETSRGPWKLLALLYYPALYYPLAACASAGHQAAFLLGTVLSWAHFGVQVWQKAECPQDPKIYKHYSLLASLPLLLGLGFLSLWYPVQLVQSLRHRTGAGSQGLQTSYSEKYLRTLLCPKKLDSCSHPASKRSLLSRAWAFSHHSIYTPQPGFRLPLKLVISATLTGTATYQVALLLLVSVVPTVQKVRAGINTDVSYLLAGFGIVLSEDRQEVVELVKHHLWTVEACYISALVLSCASTFLLLIRSLRTHRANLQALHRGAALDLDPPLQSIHPSRQAIVSWMSFCAYQTAFSCLGLLVQQVIFFLGTTSLAFLVFVPLLHGRNLLLLRSLESTWPFWLTVALAVILQNIAANWIFLRTHHGYPELTNRRMLCVATFLLFPINMLVGAIMAVWRVLISSLYNTVHLGQMDLSLLPQRAASLDPGYHTYQNFLRIEASQSHPGVIAFCALLLHAPSPQPRPPLAPQDSLRPAEEEEGMQLLQTKDLMAKGAGHKGSQSRARWGLAYTLLHNPSLQAFRKAALTSAKANGTQP", "length": 670, "molWeight": 73775, "crc64": "6ACE69F3EE16A4F7", "md5": "FF1E31952F65C934CC337772C37229E4"}}
{"primaryAccession": "O74563", "text": "This is E3 ubiquitin-protein ligase brl2 protein, from Fission yeast, contains 680 amino acids, has 1 RING-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [627, 667], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "O74563", "organism_name": "Fission yeast", "protein_name": "E3 ubiquitin-protein ligase brl2", "length": 680, "firstPublicDate": "2005-12-20", "FUNCTION": "E3 ubiquitin-protein ligase which belongs to the histone H2B ubiquitin ligase complex (HULC) which mediates monoubiquitination of histone H2B to form H2BK123ub1, H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the BRE1 family", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MYQNGKPDAPTILGQKRELEDVEIQDDDIQEVSKEDLLKDVRVRSIQFDELESKIEGLQNLAEEKLKVLATLVSWWPEILQQFSVVFQGNELKDFESEGVFSILEKFPELSYFNDAVKNNKTKALSIIQKLLSTVDSSTNSVSRDPFSVLSIDDSALTEKLNTINLDIDKILDELDTTRSQLHSIIKLPDRSSSFTLQCINESVRPQSTKVKEEATTSSKGKDEEKKVSTVEQRTQLQQLSRLQDQQNGLMESRSQSLKILDSNVNEMDKLIMERENALNNVETTNLKKYSSFLALKEAVSMTSEQLRVLEHLLSECSHEINVLSQQSKNFNGVFESSYQPLINDLDHQISVMQNDEKRINNAKTELSLSLEKKLEAKKQKEKVYKDKLDELANLETMVLEKKKAVATREAANKIRLVDLNDLELQKDLSTYLSKELASTEKAFRLVKQQTVKSSHSHYQELITKFSVEKEKAEQKYFLTMKSTDSLHAEVKLLRQKYQKTNEIISKMLNSQDTAVHRIIEFEDQLARLSSVRNNSIKQSTTFQVKKSSQKSTIQNLEEKVSYLQQFMDKNNATLTDLEFQCSDLSSSIDILSKQDEEHEKEKRKLKDTGVSTSAEELKTFRAMCKCSVCNFERWKDRIISLCGHGFCYQCIQKRIETRQRRCPICGRGFGASDVIPIHL", "length": 680, "molWeight": 78053, "crc64": "61B90DE682436705", "md5": "E6808D4DE42E9D953B3E6D8128516AD9"}}
{"primaryAccession": "O75001", "text": "This is DNA replication licensing factor mcm7 protein, from Fission yeast, contains 760 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75001", "organism_name": "Fission yeast", "protein_name": "DNA replication licensing factor mcm7", "length": 760, "firstPublicDate": "2001-01-11", "FUNCTION": "Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells, Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built, The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit, The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity), Required for the progression of S phase (PubMed:11606526)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCM family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALPTIDLKIPEYEECQHKITDFLSHFKQEQVQDGQQNQDISMSDAGDEPFLKSKYMDILQKISNRESNVINVDLNDLYEFDPSDTQLLHNIESNAKRFVELFSQCADALMPPPTVEINYRNEVLDVIMQQRVQRNENIDPEHKGFPPELTRGYDLYFRPVTRNKKPFSVRDLRGENLGSLLTVRGIVTRTSDVKPSLTVNAYTCDRCGYEVFQEIRQKTFLPMSECPSDECKKNDAKGQLFMSTRASKFLPFQEVKIQELTNQVPIGHIPRSLTVHLYGAITRSVNPGDIVDISGIFLPTPYTGFRAMRAGLLTDTYLECHYVSQIIKNYTNIEKTPQSEAAIAELNQGGNVYEKLAKSIAPEIYGHEDVKKALLLLLVGGVTKELGDGMRIRGDINICLTGDPGVAKSQLLKYISKVAPRGVYTTGRGSSGVGLTAAVMRDPVTDEMVLEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGITTTLNARTSILAAANPLYGRYNPKVAPIHNINLPAALLSRFDILFLILDTPSRETDEHLAQHVTYVHMHNEQPKMDFEPLDPNMIRHYISSARQYRPVVPKDVCDYVTGAYVQLRQNQKRDEANERQFAHTTPRTLLAILRMGQALARLRFSNRVEIGDVDEALRLMSVSKSSLYDDLDPSSHDTTITSKIYKIIRDMLNSIPDVEGNERSLTLRAIRERVLAKGFTEDHLINTIQEYTDLGVLLTTNNGQTIMFLDPDLHMEN", "length": 760, "molWeight": 85622, "crc64": "2141F8F9CB0BAA34", "md5": "A27B61DC222C269E513AC2FEEFDBE8CE"}}
{"primaryAccession": "O75072", "text": "This is Ribitol-5-phosphate transferase FKTN protein, from Human, contains 461 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75072", "organism_name": "Human", "protein_name": "Ribitol-5-phosphate transferase FKTN", "length": 461, "firstPublicDate": "2001-02-21", "FUNCTION": "Catalyzes the transfer of a ribitol-phosphate from CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:26923585, PubMed:29477842, PubMed:27194101), This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-beta-1 (PubMed:17034757, PubMed:25279699, PubMed:26923585, PubMed:29477842, PubMed:27194101), Required for normal location of POMGNT1 in Golgi membranes, and for normal POMGNT1 activity (PubMed:17034757), May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes (PubMed:25279699), Could be involved in brain development (Probable)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the LicD transferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSRINKNVVLALLTLTSSAFLLFQLYYYKHYLSTKNGAGLSKSKGSRIGFDSTQWRAVKKFIMLTSNQNVPVFLIDPLILELINKNFEQVKNTSHGSTSQCKFFCVPRDFTAFALQYHLWKNEEGWFRIAENMGFQCLKIESKDPRLDGIDSLSGTEIPLHYICKLATHAIHLVVFHERSGNYLWHGHLRLKEHIDRKFVPFRKLQFGRYPGAFDRPELQQVTVDGLEVLIPKDPMHFVEEVPHSRFIECRYKEARAFFQQYLDDNTVEAVAFRKSAKELLQLAAKTLNKLGVPFWLSSGTCLGWYRQCNIIPYSKDVDLGIFIQDYKSDIILAFQDAGLPLKHKFGKVEDSLELSFQGKDDVKLDVFFFYEETDHMWNGGTQAKTGKKFKYLFPKFTLCWTEFVDMKVHVPCETLEYIEANYGKTWKIPVKTWDWKRSPPNVQPNGIWPISEWDEVIQLY", "length": 461, "molWeight": 53724, "crc64": "2D11F28E4BCCD858", "md5": "A2BAC271EE41CE83E47EBDEF0E456B1F"}}
{"primaryAccession": "O75170", "text": "This is Serine/threonine-protein phosphatase 6 regulatory subunit 2 protein, from Human, contains 966 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75170", "organism_name": "Human", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 2", "length": 966, "firstPublicDate": "2002-11-25", "FUNCTION": "Regulatory subunit of protein phosphatase 6 (PP6), May function as a scaffolding PP6 subunit, Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the SAPS family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFWKFDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLLDFLCRQQCMEELVSLITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDRLGGDESLLSLLYDFLDHEPPLNPLLASFFSKTIGNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAGLRQDVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEALEPDPLLTALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVGTEGLVDSFSQGLERSYAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVLEEPLGNARLHGARLMAALLHTNTPSINQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCIAAILSHAAREERTEASGSESRVEPPHENGNRSLETPQPAASLPDNTMVTHLFQKCCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLERGPVQTHISEVIRGLPADCRGRWESFVEETLTETNRRNTVDLVSTHHLHSSSEDEDIEGAFPNELSLQQAFSDYQIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADEDSPSAALFEACCSDRIQPFDDDEDEDIWEDSDTRCAARVMARPRFGAPHASESCSKNGPERGGQDGKASLEAHRDAPGAGAPPAPGKKEAPPVEGDSEGAMWTAVFDEPANSTPTAPGVVRDVGSSVWAAGTSAPEEKGWAKFTDFQPFCCSESGPRCSSPVDTECSHAEGSRSQGPEKASQASYFAVSPASPCAWNVCVTRKAPLLASDSSSSGGSHSEDGDQKAASAMDAVSRGPGREAPPLPTVARTEEAVGRVGCADSRLLSPACPAPKEVTAAPAVAVPPEATVAITTALSKAGPAIPTPAVSSALAVAVPLGPIMAVTAAPAMVATLGTVTKDGKTDAPPEGAALNGPV", "length": 966, "molWeight": 104942, "crc64": "D3BC10EADB98FB62", "md5": "615B87415D3ABE121307B06374AA960A"}}
{"primaryAccession": "O75324", "text": "This is Stannin protein, from Human, contains 88 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75324", "organism_name": "Human", "protein_name": "Stannin", "length": 88, "firstPublicDate": "1998-12-15", "FUNCTION": "Plays a role in the toxic effects of organotins (PubMed:15269288), Plays a role in endosomal maturation (PubMed:27015288)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the stannin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSIMDHSPTTGVVTVIVILIAIAALGALILGCWCYLRLQRISQSEDEESIVGDGETKEPFLLVQYSAKGPCVERKAKLMTPNGPEVHG", "length": 88, "molWeight": 9497, "crc64": "1E8DA73323C5D6DF", "md5": "242748FCFEA695C3C8A42803F6B2A343"}}
{"primaryAccession": "O75367", "text": "This is Core histone macro-H2A.1 protein, from Human, contains 369 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75367", "organism_name": "Human", "protein_name": "Core histone macro-H2A.1", "length": 369, "firstPublicDate": "2001-01-24", "FUNCTION": "In contrast to isoform 1, does not bind poly-ADP-ribose (PubMed:15902274), Represses SOD3 gene expression (PubMed:23022728)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN", "length": 369, "molWeight": 39184, "crc64": "D21A4CE6C7AA3BB1", "md5": "3834940FE763831FB458643ECA46EA6E"}}
{"primaryAccession": "O75462", "text": "This is Cytokine receptor-like factor 1 protein, from Human, contains 422 amino acids, has 1 Ig-like C2-type Immunoglobulin domain, is soluble, locates in Extracellular.", "functionDomainRange": [{"location": [38, 131], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "O75462", "organism_name": "Human", "protein_name": "Cytokine receptor-like factor 1", "length": 422, "firstPublicDate": "2004-03-01", "FUNCTION": "In complex with CLCF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (Probable), May also play a regulatory role in the immune system", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the type I cytokine receptor family, Type 3 subfamily", "domain_description": {"Ig-like C2-type Immunoglobulin domain": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPAGRRGPAAQSARRPPPLLPLLLLLCVLGAPRAGSGAHTAVISPQDPTLLIGSSLLATCSVHGDPPGATAEGLYWTLNGRRLPPELSRVLNASTLALALANLNGSRQRSGDNLVCHARDGSILAGSCLYVGLPPEKPVNISCWSKNMKDLTCRWTPGAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPGPGGGACEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQDEGILPSGRRGTARGPAR", "length": 422, "molWeight": 46302, "crc64": "AD9DEFCB01B84228", "md5": "C7CBB933B8E2667654755EFA3FADC5EC"}}
{"primaryAccession": "O75475", "text": "This is PC4 and SFRS1-interacting protein protein, from Human, contains 530 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75475", "organism_name": "Human", "protein_name": "PC4 and SFRS1-interacting protein", "length": 530, "firstPublicDate": "2005-07-05", "FUNCTION": "Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis, Involved in particular in lens epithelial cell gene regulation and stress responses, May play an important role in lens epithelial to fiber cell terminal differentiation, May play a protective role during stress-induced apoptosis, Isoform 2 is a more general and stronger transcriptional coactivator, Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing, Cellular cofactor for lentiviral integration", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the HDGF family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNGGSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN", "length": 530, "molWeight": 60103, "crc64": "4B653D02B1D0E174", "md5": "6266D7D911CA0EBD0A842FF3BB63C08C"}}
{"primaryAccession": "O75554", "text": "This is WW domain-binding protein 4 protein, from Human, contains 376 amino acids, has 1 Matrin-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [11, 42], "description": "Matrin-type", "keyword_description": "Zinc finger", "textural_description": "Matrin-type Zinc finger"}], "meta_data": {"primaryAccession": "O75554", "organism_name": "Human", "protein_name": "WW domain-binding protein 4", "length": 376, "firstPublicDate": "2005-06-07", "FUNCTION": "Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:9724750, PubMed:19592703, PubMed:28781166), May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex (PubMed:9724750)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"Matrin-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFKEKTVTSLGVMADGVAPVFKKRRTENGKSRNLRQRGDDQ", "length": 376, "molWeight": 42507, "crc64": "7A122A29D4325D11", "md5": "A0B32AC3A7C7584F487209EC37594891"}}
{"primaryAccession": "O75607", "text": "This is Nucleoplasmin-3 protein, from Human, contains 178 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75607", "organism_name": "Human", "protein_name": "Nucleoplasmin-3", "length": 178, "firstPublicDate": "2000-05-30", "FUNCTION": "Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning (PubMed:22362753, PubMed:20073534), Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM (PubMed:22362753), Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM (PubMed:15596447)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the nucleoplasmin family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAGTAAALAFLSQESRTRAGGVGGLRVPAPVTMDSFFFGCELSGHTRSFTFKVEEEDDAEHVLALTMLCLTEGAKDECNVVEVVARNHDHQEIAVPVANLKLSCQPMLSLDDFQLQPPVTFRLKSGSGPVRITGRHQIVTMSNDVSEEESEEEEEDSDEEEVELCPILPAKKQGGRP", "length": 178, "molWeight": 19344, "crc64": "8C899DE8C3CD61FA", "md5": "77AE702725CF3705855CB77B97FA8A12"}}
{"primaryAccession": "O75879", "text": "This is Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial protein, from Human, contains 557 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75879", "organism_name": "Human", "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "length": 557, "firstPublicDate": "2000-05-30", "FUNCTION": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria, The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the GatB/GatE family, GatB subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAPMLRWGCRGRRWAFARVDGGSCHRRGAPTGSTSNQIRGESSVAQQPLHTAQKTRKGEHKWAAVVGLEIHAQISSNSKLFSGSQVRFSAPPNSLVSFFDASLPGTLPVLNRRCVEAAVMTGLALNCHINKKSLFDRKHYFYADLPAGYQITQQRLPIAVNGSLIYGVCAGKKQSQVIPKTVRIKQIQLEQDSGKSLHDNLRSQTLIDLNRAGVGLLEVVLEPDMSCGEEAATAVRELQLILQALGTSQANMAEGQLRVDANISVHHPGEPLGVRTEVKNLNSIRFLAKAIDYEIQRQINELENGGEILNETRSFHHKLGCTMSMRDKEGKQDYRFMPEPNLPPLVLYDATSLPAGADPQQVINIDQIRETLPELPSVTREKLVQQYGMLLEHSFTLLNEVGLLEFFQNVIKETRAEPKKVTSWVLNTFLGYLKQQNLAVSESPVTPSALAELLDLLDSRTISSSAAKQVFEELWKREGKTPGQIVSEKQLELMQDQGALEQLCHSVMEAHPQVVMDVKNRNPRAINKLIGLVRKATQSRADPVMIKEILEKKLSL", "length": 557, "molWeight": 61864, "crc64": "449EB3EA2FD4769D", "md5": "6B03AD310F83463041023544FC77B2AA"}}
{"primaryAccession": "O75909", "text": "This is Cyclin-K protein, from Human, contains 580 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75909", "organism_name": "Human", "protein_name": "Cyclin-K", "length": 580, "firstPublicDate": "2000-12-01", "FUNCTION": "Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases, Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the cyclin family, Cyclin C subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR", "length": 580, "molWeight": 64240, "crc64": "8A945E90359AD9F8", "md5": "FD9634B78575A2C5458220B46DE745A0"}}
{"primaryAccession": "O75934", "text": "This is Pre-mRNA-splicing factor SPF27 protein, from Human, contains 225 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75934", "organism_name": "Human", "protein_name": "Pre-mRNA-splicing factor SPF27", "length": 225, "firstPublicDate": "2005-05-10", "FUNCTION": "Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:28502770, PubMed:28076346, PubMed:29360106, PubMed:29301961, PubMed:30705154), Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing, May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex, The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SPF27 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF", "length": 225, "molWeight": 26131, "crc64": "9112718EEFD96890", "md5": "DD72D4FB5BB270DA41A08ACD50FD7511"}}
{"primaryAccession": "O76090", "text": "This is Bestrophin-1 protein, from Human, contains 585 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O76090", "organism_name": "Human", "protein_name": "Bestrophin-1", "length": 585, "firstPublicDate": "1999-07-15", "FUNCTION": "Forms calcium-sensitive chloride channels, Highly permeable to bicarbonate", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the anion channel-forming bestrophin (TC 1,A,46) family, Calcium-sensitive chloride channel subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRDEAHS", "length": 585, "molWeight": 67684, "crc64": "D0629AAF65BA1ACD", "md5": "D1EF33E53DDF9C6E6AF3CE220D6E437A"}}
{"primaryAccession": "O76927", "text": "This is Small ribosomal subunit protein eS21 protein, from Fruit fly, contains 83 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O76927", "organism_name": "Fruit fly", "protein_name": "Small ribosomal subunit protein eS21", "length": 83, "firstPublicDate": "2010-07-13", "FUNCTION": "May be an associated component of the ribosome rather than a core structural subunit, May act as a translation initiation factor, Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS21 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MENDAGENVDLYVPRKCSASNRIIHAKDHASVQLSIVDVDPETGRQTDGSKTYAICGEIRRMGESDDCIVRLAKKDGIITKNF", "length": 83, "molWeight": 9167, "crc64": "DDFB9D498B3E1E05", "md5": "FB6C903128CD355B6618A5EE72363077"}}
{"primaryAccession": "O80885", "text": "This is Membrane metalloprotease ARASP, chloroplastic protein, from Mouse-ear cress, contains 447 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O80885", "organism_name": "Mouse-ear cress", "protein_name": "Membrane metalloprotease ARASP, chloroplastic", "length": 447, "firstPublicDate": "2015-04-01", "FUNCTION": "Metalloprotease essential for chloroplast and plant development, May be involved in regulated intramembrane proteolysis (RIP)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the peptidase M50A family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLLNISSSPISHRNPHFLSNFNNPISYFPRRSKTHLSKSHFFPKFTPLSNQSLKNRVLFGNKRYPDGERFDFRSRAISGIDLGSFESVLEAIAVLTTIIVVHESGHFLAASLQGIHVSKFAIGFGPILAKFDYNNVEYSLRAFPLGGFVGFPDNDPDSEIPIDDENLLKNRPTLDRSIVVSAGIIANVIFAYAIIFVQVLSVGLPVQEAFPGVLVPEVKTFSAASRDGLLSGDVILAVDGTELSKTGPDAVSKIVDIVKRNPKSNVVFRIERGGEDFDIRVTPDKNFDGTGKIGVQLSPNVRITKVRPRNIPETFRFVGREFMGLSSNVLDGLKQTFFNFSQTASKVAGPVAIIAVGAEVARSNIDGLYQFAALLNINLAVINLLPLPALDGGTLALILLEAVRGGKKLPVEVEQGIMSSGIMLVIFLGLFLIVKDTLSLDFIKEML", "length": 447, "molWeight": 48726, "crc64": "152A261C32920664", "md5": "E987EEC9CD37B1E6A7BE27C1465018CB"}}
{"primaryAccession": "O80931", "text": "This is Transcription factor AS1 protein, from Mouse-ear cress, contains 367 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O80931", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor AS1", "length": 367, "firstPublicDate": "2003-03-28", "FUNCTION": "Transcription factor required for normal cell differentiation, Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV, Interacts directly with ASYMMETRIC LEAVES 2 (LBD6/AS2) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5, May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis (PubMed:11076771, PubMed:11140682, PubMed:11882937, PubMed:12750468, PubMed:16006579, PubMed:16699177, PubMed:17395603, PubMed:17559509, PubMed:23271976), Binds directly to KNAT1, KNAT2, and KNATM chromatin, regulating leaf development (PubMed:23271976), LBD6 is required for this binding (PubMed:23271976), Positive regulator of flowering that binds to the promoter of FT (PubMed:21950734), Regulates FT expression by forming a functional complex with CO (PubMed:21950734), Involved in leaf polarity establishment by functioning cooperatively with NUCL1 to repress abaxial genes ARF3, ARF4, KAN1, KAN2, YAB1 and YAB5, and the knox homeobox genes KNAT1, KNAT2, KNAT6, and STM to promote adaxial development in leaf primordia at shoot apical meristems at high temperatures (PubMed:27334696)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKERQRWSGEEDALLRAYVRQFGPREWHLVSERMNKPLNRDAKSCLERWKNYLKPGIKKGSLTEEEQRLVIRLQEKHGNKWKKIAAEVPGRTAKRLGKWWEVFKEKQQREEKESNKRVEPIDESKYDRILESFAEKLVKERSNVVPAAAAAATVVMANSNGGFLHSEQQVQPPNPVIPPWLATSNNGNNVVARPPSVTLTLSPSTVAAAAPQPPIPWLQQQQPERAENGPGGLVLGSMMPSCSGSSESVFLSELVECCRELEEGHRAWADHKKEAAWRLRRLELQLESEKTCRQREKMEEIEAKMKALREEQKNAMEKIEGEYREQLVGLRRDAEAKDQKLADQWTSRHIRLTKFLEQQMGCRLDRP", "length": 367, "molWeight": 42243, "crc64": "24D9085193E6088B", "md5": "04D3BE2E59539F20F97A033200836082"}}
{"primaryAccession": "O80939", "text": "This is L-type lectin-domain containing receptor kinase IV.1 protein, from Mouse-ear cress, contains 675 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O80939", "organism_name": "Mouse-ear cress", "protein_name": "L-type lectin-domain containing receptor kinase IV.1", "length": 675, "firstPublicDate": "2011-01-11", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "In the N-terminal section; belongs to the leguminous lectin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFLKLLTIFFFFFFNLIFQSSSQSLNFAYNNGFNPPTDLSIQGITTVTPNGLLKLTNTTVQKTGHAFYTKPIRFKDSPNGTVSSFSTSFVFAIHSQIAILSGHGIAFVVAPNASLPYGNPSQYIGLFNLANNGNETNHVFAVELDTILSTEFNDTNDNHVGIDINSLKSVQSSPAGYWDEKGQFKNLTLISRKPMQVWVDYDGRTNKIDVTMAPFNEDKPTRPLVTAVRDLSSVLLQDMYVGFSSATGSVLSEHYILGWSFGLNEKAPPLALSRLPKLPRFEPKRISEFYKIGMPLISLFLIFSFIFLVCYIVRRRRKFAEELEEWEKEFGKNRFRFKDLYYATKGFKEKGLLGTGGFGSVYKGVMPGTKLEIAVKRVSHESRQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNTPEVTLNWKQRIKVILGVASGLFYLHEEWEQVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGSDPQTTHVVGTLGYLAPEHTRTGRATMATDVFAFGAFLLEVACGRRPIEFQQETDETFLLVDWVFGLWNKGDILAAKDPNMGSECDEKEVEMVLKLGLLCSHSDPRARPSMRQVLHYLRGDAKLPELSPLDLSGSGMMFGVHDGFSELGMSYSSSVFKGFTGGSSIADSQLSGGR", "length": 675, "molWeight": 75541, "crc64": "C3F2437E6ABA9967", "md5": "A27159DBC0761E5CB483E5C53A6492B4"}}
{"primaryAccession": "O81242", "text": "This is DNA-binding protein RHL1 protein, from Mouse-ear cress, contains 355 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O81242", "organism_name": "Mouse-ear cress", "protein_name": "DNA-binding protein RHL1", "length": 355, "firstPublicDate": "2008-09-02", "FUNCTION": "Component of the DNA topoisomerase VI complex involved in chromatin organization and progression of endoreduplication cycles, Binds to DNA, Required for endoreduplication beyond 8C", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVRASSSKKGGSKGGDKDDAESKQRKRLKTLALDNQLLSDSPAKSHSSLKPSKQVLKHHGTDIIRKSQRKNRFLFSFPGLLAPISAATIGDLDRLSTKNPVLYLNFPQGRMKLFGTILYPKNRYLTLQFSRGGKNVLCDDYFDNMIVFSESWWIGTKEENPEEARLDFPKELAQAENTEFDFQGGAGGAASVKKLASPEIGSQPTETDSPEVDNEDVLSEDGEFLDDKIQVTPPVQLTPPVQVTPVRQSQRNSGKKFNFAETSSEASSGESEGNTSDEDEKPLLEPESSTRSREESQDGNGITASASKLPEELPAKREKLKSKDSKLVQATLSNLFKKAEEKTAGTSKAKSSSKA", "length": 355, "molWeight": 38904, "crc64": "D0B2EA050D5095BA", "md5": "EF90DC8BC6F21116A5BBF158502401C1"}}
{"primaryAccession": "O81645", "text": "This is Villin-3 protein, from Mouse-ear cress, contains 965 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O81645", "organism_name": "Mouse-ear cress", "protein_name": "Villin-3", "length": 965, "firstPublicDate": "2002-11-15", "FUNCTION": "Binds actin and actin filament bundles in a Ca(2+)-insensitive manner, but severs actin filaments in a calcium-dependent manner, regardless of the presence or not of VLN1 (AC O81643), Acts redundantly with VLN2 (AC O81644) to generate thick actin filament bundles, to regulate directional organ growth (PubMed:22209875) and in sclerenchyma development (PubMed:22563899)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the villin/gelsolin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSGSTKVLDPAFQGVGQKPGTEIWRIENFEPVPVPKSEHGKFYMGDTYIVLQTTQNKGGAYLFDIHFWIGKDTSQDEAGTAAVKTVELDAALGGRAVQYREIQGHESDKFLSYFKPCIIPLEGGVASGFKKPEEEEFETRLYTCKGKRAVHLKQVPFARSSLNHDDVFILDTKEKIYQFNGANSNIQERAKALVVIQYLKDKFHEGTSDVAIVDDGKLDTESDSGEFWVLFGGFAPIARKVASEDEIIPETTPPKLYSIADGQVESIDGDLSKSMLENNKCYLLDCGSEIFIWVGRVTQVEERKTAIQAAEDFVASENRPKATRITRVIQGYEPHSFKSNFDSWPSGSATPANEEGRGKVAALLKQQGVGLKGLSKSTPVNEDIPPLLEGGGKLEVWYIDANSKTVLSKDHVGKLYSGDCYLVLYTYHSGERKEDYFLCCWFGKNSNQEDQETAVRLASTMTNSLKGRPVQARIFEGKEPPQFVALFQHMVVLKGGLSSGYKNSMTEKGSSGETYTPESIALIQVSGTGVHNNKALQVEAVATSLNSYDCFLLQSGTSMFLWVGNHSTHEQQELAAKVAEFLKPGTTIKHAKEGTESSSFWFALGGKQNFTSKKVSSETVRDPHLFSFSFNRGKFQVEEIHNFDQDDLLTEEMHLLDTHAEVFVWVGQCVDPKEKQTAFEIGQRYINLAGSLEGLSPKVPLYKITEGNEPCFFTTYFSWDSTKATVQGNSYQKKAALLLGTHHVVEDQSSSGNQGPRQRAAALAALTSAFNSSSGRTSSPSRDRSNGSQGGPRQRAEALAALTSAFNSSPSSKSPPRRSGLTSQASQRAAAVAALSQVLTAEKKKSPDTSPSAEAKDEKAFSEVEATEEATEAKEEEEVSPAAEASAEEAKPKQDDSEVETTGVTFTYERLQAKSEKPVTGIDFKRREAYLSEVEFKTVFGMEKESFYKLPGWKQDLLKKKFNLF", "length": 965, "molWeight": 106349, "crc64": "1571DB7D6EF1B6A8", "md5": "597473B444EBDECCBF1FB6F5AAC88184"}}
{"primaryAccession": "O82261", "text": "This is Protease Do-like 2, chloroplastic protein, from Mouse-ear cress, contains 607 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O82261", "organism_name": "Mouse-ear cress", "protein_name": "Protease Do-like 2, chloroplastic", "length": 607, "firstPublicDate": "2006-01-24", "FUNCTION": "Serine protease that performs the primary cleavage of the photodamaged D1 protein in plant photosystem II", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the peptidase S1C family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAASVANCCFSVLNASVKIQSSSISSPWCFVSASSLTPRASSNIKRKSSRSDSPSPILNPEKNYPGRVRDESSNPPQKMAFKAFGSPKKEKKESLSDFSRDQQTDPAKIHDASFLNAVVKVYCTHTAPDYSLPWQKQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVKRRGDDRKYVAKVLVRGVDCDIALLSVESEDFWKGAEPLRLGHLPRLQDSVTVVGYPLGGDTISVTKGVVSRIEVTSYAHGSSDLLGIQIDAAINPGNSGGPAFNDQGECIGVAFQVYRSEETENIGYVIPTTVVSHFLTDYERNGKYTGYPCLGVLLQKLENPALRECLKVPTNEGVLVRRVEPTSDASKVLKEGDVIVSFDDLHVGCEGTVPFRSSERIAFRYLISQKFAGDIAEIGIIRAGEHKKVQVVLRPRVHLVPYHIDGGQPSYIIVAGLVFTPLSEPLIEEECEDTIGLKLLTKARYSVARFRGEQIVILSQVLANEVNIGYEDMNNQQVLKFNGIPIRNIHHLAHLIDMCKDKYLVFEFEDNYVAVLEREASNSASLCILKDYGIPSERSADLLEPYVDPIDDTQALDQGIGDSPVSNLEIGFDGLVWA", "length": 607, "molWeight": 66802, "crc64": "2E1A319A4D48A9C3", "md5": "057CCF196EAA9FCFD144EE03C9920855"}}
{"primaryAccession": "O82268", "text": "This is Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 3 protein, from Mouse-ear cress, contains 219 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O82268", "organism_name": "Mouse-ear cress", "protein_name": "Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 3", "length": 219, "firstPublicDate": "2014-02-19", "FUNCTION": "Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity), Required for the maintenance of the shoot apical meristem and for the formation of lateral organs, Promotes petal formation and growth, but may suppress organ differentiation in the boundary region", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the plant homeotic and developmental regulators ALOG protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDMIPQLMEGSSAYGGVTNLNIISNNSSSVTGATGGEATQPLSSSSSPSANSSRYENQKRRDWNTFGQYLRNHRPPLSLSRCSGAHVLEFLRYLDQFGKTKVHTNICHFYGHPNPPAPCPCPLRQAWGSLDALIGRLRAAFEENGGKPETNPFGARAVRLYLREVRDMQSKARGVSYEKKKRKRPLPSSSTSSSSAVASHQQFQMLPGTSSTTQLKFEK", "length": 219, "molWeight": 24123, "crc64": "57C7DFE1537FCA5D", "md5": "90685FA248FA83D5D2E55687E27FA2DF"}}
{"primaryAccession": "O82743", "text": "This is Agamous-like MADS-box protein AGL19 protein, from Mouse-ear cress, contains 219 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O82743", "organism_name": "Mouse-ear cress", "protein_name": "Agamous-like MADS-box protein AGL19", "length": 219, "firstPublicDate": "2001-01-11", "FUNCTION": "Probable transcription factor that promotes flowering, especially in response to vernalization by short periods of cold, in an FLC-inpedendent manner", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVRGKTEMKRIENATSRQVTFSKRRNGLLKKAFELSVLCDAEVALVIFSPRSKLYEFSSSSIAATIERYQRRIKEIGNNHKRNDNSQQARDETSGLTKKIEQLEISKRKLLGEGIDACSIEELQQLENQLDRSLSRIRAKKYQLLREEIEKLKAEERNLVKENKDLKEKWLGMGTATIASSQSTLSSSEVNIDDNMEVETGLFIGPPETRQSKKFPPQN", "length": 219, "molWeight": 25049, "crc64": "663740DC9D5F4A7A", "md5": "3DBA4100BB5FDAFFC8630030D1C58DCC"}}
{"primaryAccession": "O82804", "text": "This is Protein EARLY FLOWERING 3 protein, from Mouse-ear cress, contains 695 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O82804", "organism_name": "Mouse-ear cress", "protein_name": "Protein EARLY FLOWERING 3", "length": 695, "firstPublicDate": "2003-02-01", "FUNCTION": "May be a transcription factor part of a circadian clock input pathway, Acts within a 'zeitnehmer' feedback loop and is involved in its own circadian regulation, Has no role in regulating circadian clock function in the dark, Part of a corepressor complex consisting of ELF4, ELF3, and LUX involved in the transcriptional regulation of APRR9, The activity of the protein may be decreased in long day conditions due to its interaction with phytochrome B (phyB), Can regulate the initiation of flowering independently of phyB, Also involved in responses to nematode parasitism, like the formation of the nematode feeding structure", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKRGKDEEKILEPMFPRLHVNDADKGGPRAPPRNKMALYEQLSIPSQRFGDHGTMNSRSNNTSTLVHPGPSSQPCGVERNLSVQHLDSSAANQATEKFVSQMSFMENVRSSAQHDQRKMVREEEDFAVPVYINSRRSQSHGRTKSGIEKEKHTPMVAPSSHHSIRFQEVNQTGSKQNVCLATCSKPEVRDQVKANARSGGFVISLDVSVTEEIDLEKSASSHDRVNDYNASLRQESRNRLYRDGGKTRLKDTDNGAESHLATENHSQEGHGSPEDIDNDREYSKSRACASLQQINEEASDDVSDDSMVDSISSIDVSPDDVVGILGQKRFWRARKAIANQQRVFAVQLFELHRLIKVQKLIAASPDLLLDEISFLGKVSAKSYPVKKLLPSEFLVKPPLPHVVVKQRGDSEKTDQHKMESSAENVVGRLSNQGHHQQSNYMPFANNPPASPAPNGYCFPPQPPPSGNHQQWLIPVMSPSEGLIYKPHPGMAHTGHYGGYYGHYMPTPMVMPQYHPGMGFPPPGNGYFPPYGMMPTIMNPYCSSQQQQQQQPNEQMNQFGHPGNLQNTQQQQQRSDNEPAPQQQQQPTKSYPRARKSRQGSTGSSPSGPQGISGSKSFRPFAAVDEDSNINNAPEQTMTTTTTTTRTTVTQTTRDGGGVTRVIKVVPHNAKLASENAARIFQSIQEERKRYDSSKP", "length": 695, "molWeight": 77206, "crc64": "607A0720ED381C08", "md5": "F321ACF37D691A7DC38B18A713E85F16"}}
{"primaryAccession": "O88291", "text": "This is DBIRD complex subunit ZNF326 protein, from Mouse, contains 580 amino acids, has 2 C2H2 AKAP95-type Zinc finger, is soluble, locates in Nucleus.", "functionDomainRange": [{"location": [314, 336], "description": "C2H2 AKAP95-type", "keyword_description": "Zinc finger", "textural_description": "C2H2 AKAP95-type Zinc finger"}, {"location": [407, 430], "description": "C2H2 AKAP95-type", "keyword_description": "Zinc finger", "textural_description": "C2H2 AKAP95-type Zinc finger"}], "meta_data": {"primaryAccession": "O88291", "organism_name": "Mouse", "protein_name": "DBIRD complex subunit ZNF326", "length": 580, "firstPublicDate": "2005-08-16", "FUNCTION": "Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions (By similarity), May also play a role in neuronal differentiation, Able to bind DNA and activate expression in vitro", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the AKAP95 family", "domain_description": {"C2H2 AKAP95-type Zinc finger": 2}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDFEDDYVHSTCRGAYQDFNGMDRDYGPGSYGGLDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQTRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRSYDAFGGPSTGRGRGRGHMGDFGSFHRPGIIVDYQNKPANVTIATARGIKRKMMQIFIKPGGAFIKKPKLAKPMDKMNLSKSPTKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVVMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDIMEGVTADDHMMKVETVHCSACSVYIPALHSSVQLHLKSPDHSKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHPQDQQIEGDEEDEEKIDEPIEEEEEEEEEEEEEGEEAGSVEEEGDVEGEEGTAEAAAAGEADAVGEAEGAGEAEEAEEEEEEEGTQEFAAQACATEQCEHRQM", "length": 580, "molWeight": 65225, "crc64": "EF9672513D0FFC70", "md5": "F8956B1EF45D6D4997330848C37EAD74"}}
{"primaryAccession": "O88703", "text": "This is Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 protein, from Mouse, contains 863 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O88703", "organism_name": "Mouse", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "length": 863, "firstPublicDate": "2003-02-28", "FUNCTION": "Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions, Contributes to the native pacemaker currents in heart (If) and in neurons (Ih), Can also transport ammonium in the distal nephron, Produces a large instantaneous current", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the potassium channel HCN family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDARGGGGRPGDSPGTTPAPGPPPPPPPPAPPQPQPPPAPPPNPTTPSHPESADEPGPRARLCSRDSACTPGAAKGGANGECGRGEPQCSPEGPARGPKVSFSCRGAASGPSAAEEAGSEEAGPAGEPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGLFPPPPPPQVTSAIATLQQAVAMSFCPQVARPLVGPLALGSPRLVRRAPPGPLPPAASPGPPAASPPAAPSSPRAPRTSPYGVPGSPATRVGPALPARRLSRASRPLSASQPSLPHGVPAPSPAASARPASSSTPRLGPAPTARTAAPSPDRRDSASPGAASGLDPLDSARSRLSSNL", "length": 863, "molWeight": 94722, "crc64": "17CDC4DFF07AC039", "md5": "A7B78C60F6EB1E50E9DF3E2F943B57BE"}}
{"primaryAccession": "O88705", "text": "This is Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 protein, from Mouse, contains 779 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O88705", "organism_name": "Mouse", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3", "length": 779, "firstPublicDate": "2003-02-28", "FUNCTION": "Hyperpolarization-activated potassium channel, May also facilitate the permeation of sodium ions", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the potassium channel HCN family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEEEARPAAGAGEAATPARETPPAAPAQARAASGGVPESAPEPKRRQLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAEILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLRRIGKKNSILQRKRSEPSPGSSGGVMEQHLVQHDRDMARGVRGLAPGTGARLSGKPVLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSARRSAGSPASPLVPVRAGPLLARGPWASTSRLPAPPARTLHASLSRTGRSQVSLLGPPPGGGARRLGPRGRPLSASQPSLPQRATGDGSPRRKGSGSERLPPSGLLAKPPGTVQPPRSSVPEPVTPRGPQISANM", "length": 779, "molWeight": 86641, "crc64": "D4FF151F174DECAE", "md5": "D33CFCFD1E5D751BE96FA929367222C6"}}
{"primaryAccession": "O88728", "text": "This is Interferon-induced transmembrane protein 5 protein, from Mouse, contains 134 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O88728", "organism_name": "Mouse", "protein_name": "Interferon-induced transmembrane protein 5", "length": 134, "firstPublicDate": "2010-10-05", "FUNCTION": "Required for normal bone mineralization", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the CD225/Dispanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDTSYPREDPRAPSSRKADAAAHTALSMGTPGPTPRDHMLWSVFSTMYLNLCCLGFLALVHSVKARDQKMAGNLEAARQYGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLSKLAKDSAAFFSTKFDEEDYN", "length": 134, "molWeight": 14667, "crc64": "EED20D259EEDD712", "md5": "8E0F2063F74A0DEBE08AEBE76F360917"}}
{"primaryAccession": "O88871", "text": "This is Gamma-aminobutyric acid type B receptor subunit 2 protein, from Rat, contains 940 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O88871", "organism_name": "Rat", "protein_name": "Gamma-aminobutyric acid type B receptor subunit 2", "length": 940, "firstPublicDate": "2001-01-11", "FUNCTION": "Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2 (PubMed:9872315, PubMed:9872317, PubMed:9872744), Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins (PubMed:9872317, PubMed:10658574), Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase (PubMed:9872315, PubMed:9872317, Ref,4, PubMed:10075644, PubMed:9872744, PubMed:10924501), Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis (PubMed:9872315, PubMed:9872317, PubMed:10457184, PubMed:9872744, PubMed:10924501), Plays a critical role in the fine-tuning of inhibitory synaptic transmission (PubMed:9872317, PubMed:10457184, PubMed:9872744), Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials (PubMed:9872744, PubMed:10924501), Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 3 family, GABA-B receptor subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASPPSSGQPRPPPPPPPPARLLLPLLLSLLLWLAPGAWGWTRGAPRPPPSSPPLSIMGLMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHFRWRRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAFEESMFGSKYQWIIPGWYEPAWWEQVHVEANSSRCLRRSLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQFEREYNSKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGKIILNAMNETNFFGVTGQVVFRNGERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVERYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILSLGNFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILHHAYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL", "length": 940, "molWeight": 105751, "crc64": "77BB42D833C7505D", "md5": "27F07B550D18BEEB5CA8539CA84BC5C1"}}
{"primaryAccession": "O88958", "text": "This is Glucosamine-6-phosphate isomerase 1 protein, from Mouse, contains 289 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O88958", "organism_name": "Mouse", "protein_name": "Glucosamine-6-phosphate isomerase 1", "length": 289, "firstPublicDate": "2000-05-30", "FUNCTION": "Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway, Deamination is coupled to aldo-keto isomerization mediating the metabolic flux from UDP-GlcNAc toward Fru-6P, At high ammonium level can drive amination and isomerization of Fru-6P toward hexosamines and UDP-GlcNAc synthesis (By similarity), Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and their effects on hyaluronan synthesis that occur during tissue remodeling (By similarity), Seems to trigger calcium oscillations in mammalian eggs, These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the glucosamine/galactosamine-6-phosphate isomerase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLIILEHYSQASEWAAKYIRNRIIQFNPGPDKYFTLGLPTGSTPLGCYQKLIEYYKNGDLSFQYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAADLQAECDAFEEKIQAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGDLAKVPTMALTVGVGTVMDAKEVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKEIQKSQSAKKPYSD", "length": 289, "molWeight": 32549, "crc64": "4778C0E0D74EBBB8", "md5": "6B4A676527A85941E4139D4AFCF4DA27"}}
{"primaryAccession": "O89017", "text": "This is Legumain protein, from Mouse, contains 435 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O89017", "organism_name": "Mouse", "protein_name": "Legumain", "length": 435, "firstPublicDate": "2002-06-24", "FUNCTION": "Has a strict specificity for hydrolysis of asparaginyl bonds, Can also cleave aspartyl bonds slowly, especially under acidic conditions, May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system, Required for normal lysosomal protein degradation in renal proximal tubules, Required for normal degradation of internalized EGFR, Plays a role in the regulation of cell proliferation via its role in EGFR degradation", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the peptidase C13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTWRVAVLLSLVLGAGAVPVGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANSEENPTPGVVINRPNGTDVYKGVLKDYTGEDVTPENFLAVLRGDAEAVKGKGSGKVLKSGPRDHVFIYFTDHGATGILVFPNDDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDINVYATTAANPKESSYACYYDEERGTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPPVTHLDLTPSPDVPLTILKRKLLRTNDVKESQNLIGQIQQFLDARHVIEKSVHKIVSLLAGFGETAERHLSERTMLTAHDCYQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEAPYPIDRIEMAMDKVCLSHY", "length": 435, "molWeight": 49373, "crc64": "F956B9E10098013D", "md5": "18CC2A0BDC35B5C355D8D91267971A50"}}
{"primaryAccession": "O94284", "text": "This is Sulfide:quinone oxidoreductase, mitochondrial protein, from Fission yeast, contains 459 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94284", "organism_name": "Fission yeast", "protein_name": "Sulfide:quinone oxidoreductase, mitochondrial", "length": 459, "firstPublicDate": "2002-12-13", "FUNCTION": "Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the SQRD family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLTLNSTIKSVTGSFQSASMLARFASTHHKVLVVGGGSAGISVAHQIYNKFSKYRFANDQGKDTSLKPGEIGIVDGAKYHYYQPGWTLTGAGLSSVAKTRRELASLVPADKFKLHPEFVKSLHPRENKIVTQSGQEISYDYLVMAAGIYTDFGRIKGLTEALDDPNTPVVTIYSEKYADAVYPWIEKTKSGNAIFTQPSGVLKCAGAPQKIMWMAEDYWRRHKVRSNIDVSFYTGMPTLFSVKRYSDALLRQNEQLHRNVKINYKDELVEVKGSERKAVFKNLNDGSLFERPFDLLHAVPSMRSHEFIAKSDLADKSGFVAVDQSTTQSTKFPNVFAIGDCSGLPTSKTYAAITAQAPVMVHNLWSFVNGKNLTASYNGYTSCPLLTGYGKLILAEFLYKQEPKESFGRFSRFLDQTVPRRMFYHLKKDFFPFVYWNFAVRNGKWYGSRGLIPPHFPVN", "length": 459, "molWeight": 51575, "crc64": "121F06DCC9579C04", "md5": "10F3CAF2855ACB88E572D4AB75F75176"}}
{"primaryAccession": "O94510", "text": "This is Ascus wall endo-1,3-alpha-glucanase protein, from Fission yeast, contains 433 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94510", "organism_name": "Fission yeast", "protein_name": "Ascus wall endo-1,3-alpha-glucanase", "length": 433, "firstPublicDate": "2004-08-16", "FUNCTION": "Promotes the release of ascospores from asci by hydrolyzing 1,3-alpha-glucan in the ascus wall", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the glycosyl hydrolase 71 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASLTTALPNKAVVAHFMMGLTYNYAQSDFQNDIQNAISLGLDGFVLNFGNDSWMMSKLTLMYNAADALNLQFLLYLNLDMSEMSTVPASTLVTYVQTFANRGHQARINNNVVVGTFLGQDINFGQSSVNQGWQVAFKNALASAGINIFFMPTWPLDASTIYQTYPVADGFCKWNCWPYYTSSPTSDAEDLVYIQNSKATNKKYMATVSPIFYTHFTSKNYSFFSEGLWFTRWMQLIKDQPNYVQVLTWNDYGESTYIGPTNYAADFPVIGSNSHEWVDSFTHAPLSYSLPLFIQMYKQNTTGLPSNFSGISQLYVTYRVHSKNATASSDSIPRPDNYQNSSDVISVISFAKSSYTLRVSVNGTVLGTTNVNAGVQSANVSFIVNNTAAAGLPLFQILNGTTVIAQGYGPLNILGNNSVVLYNFNFCTTRISW", "length": 433, "molWeight": 48066, "crc64": "7FA86E53523BC675", "md5": "2B6E1B843074A6EF32783E843AAA8E18"}}
{"primaryAccession": "O94753", "text": "This is Versatile peroxidase VPL2 protein, from Boletus of the steppes, contains 361 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94753", "organism_name": "Boletus of the steppes", "protein_name": "Versatile peroxidase VPL2", "length": 361, "firstPublicDate": "2007-10-23", "FUNCTION": "A versatile ligninolytic peroxidase that combines the substrate specificity characteristics of the two other ligninolytic peroxidases, manganese peroxidase and lignin peroxidase", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peroxidase family, Ligninase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSFKTLSALALALGAAVQFASAAVPLVQKRATCDDGRTTANAACCILFPILDDIQENLFDGAQCGEEVHESLRLTFHDAIGFSPTLGGGGADGSIIAFDTIETNFPANAGIDEIVSAQKPFVAKHNISAGDFIQFAGAVGVSNCPGGVRIPFFLGRPDAVAASPDHLVPEPFDSVDSILARMGDAGFSPVEVVWLLASHSIAAADKVDPSIPGTPFDSTPGVFDSQFFIETQLKGRLFPGTADNKGEAQSPLQGEIRLQSDHLLARDPQTACEWQSMVNNQPKIQNRFAATMSKMALLGQDKTKLIDCSDVIPTPPALVGAAHLPAGFSLSDVEQACAATPFPALTADPGPVTSVPPVPGS", "length": 361, "molWeight": 37624, "crc64": "18C4C6900F22A1E5", "md5": "761DD4D994796C6FD47D318686412D9B"}}
{"primaryAccession": "O94804", "text": "This is Serine/threonine-protein kinase 10 protein, from Human, contains 968 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94804", "organism_name": "Human", "protein_name": "Serine/threonine-protein kinase 10", "length": 968, "firstPublicDate": "2001-01-24", "FUNCTION": "Serine/threonine-protein kinase involved in regulation of lymphocyte migration, Phosphorylates MSN, and possibly PLK1, Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN, Acts as a negative regulator of MAP3K1/MEKK1, May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEEIEDGRDEGEEEDAVDAASTLENHTQNSSEVSPPSLNADKPLEESPSTPLAPSQSQDSVNEPCSQPSGDRSLQTTSPPVVAPGNENGLAVPVPLRKSRPVSMDARIQVAQEKQVAEQGGDLSPAANRSQKASQSRPNSSALETLGGEKLANGSLEPPAQAAPGPSKRDSDCSSLCTSESMDYGTNLSTDLSLNKEMGSLSIKDPKLYKKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSNKHELQLEQMHKRFEQEINAKKKFFDTELENLERQQKQQVEKMEQDHAVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAEQREKIKQFSQQEEKRQKSERLQQQQKHENQMRDMLAQCESNMSELQQLQNEKCHLLVEHETQKLKALDESHNQNLKEWRDKLRPRKKALEEDLNQKKREQEMFFKLSEEAECPNPSTPSKAAKFFPYSSADAS", "length": 968, "molWeight": 112135, "crc64": "15E245193ECC553D", "md5": "D86D95C0324F1FDB3E1FD11A9B7EF0D5"}}
{"primaryAccession": "O94888", "text": "This is UBX domain-containing protein 7 protein, from Human, contains 489 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94888", "organism_name": "Human", "protein_name": "UBX domain-containing protein 7", "length": 489, "firstPublicDate": "2005-08-16", "FUNCTION": "Ubiquitin-binding adapter that links a subset of NEDD8-associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAHGGSAASSALKGLIQQFTTITGASESVGKHMLEACNNNLEMAVTMFLDGGGIAEEPSTSSASVSTVRPHTEEEVRAPIPQKQEILVEPEPLFGAPKRRRPARSIFDGFRDFQTETIRQEQELRNGGAIDKKLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFACQCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTGQKLVEWHQLDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQETHFDSTQTKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKEENRRPLTEPPVRTDPGTATNHQGLPAVDSEILEMPPEKADGVVEGIDVNGPKAQLMLRYPDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCPQETVFVQERN", "length": 489, "molWeight": 54862, "crc64": "3C894533B1A2C41A", "md5": "7E6C39C3AC8EB99583F33BB3157C1D4A"}}
{"primaryAccession": "O94901", "text": "This is SUN domain-containing protein 1 protein, from Human, contains 785 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94901", "organism_name": "Human", "protein_name": "SUN domain-containing protein 1", "length": 785, "firstPublicDate": "2002-08-02", "FUNCTION": "As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton (PubMed:18039933, PubMed:18396275), The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning (By similarity), Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration (By similarity), Involved in telomere attachment to nuclear envelope in the prophase of meiosis implicating a SUN1/2:KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redundantly (By similarity), Required for gametogenesis and involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis (By similarity), Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity), Required for efficient localization of SYNE4 in the nuclear envelope (By similarity), May be involved in nuclear remodeling during sperm head formation in spermatogenesis (By similarity), May play a role in DNA repair by suppressing non-homologous end joining repair to facilitate the repair of DNA cross-links (PubMed:24375709)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK", "length": 785, "molWeight": 87110, "crc64": "1099A50C9540ECF5", "md5": "17DF03330CE3D0DAE2C3025C2A36384B"}}
{"primaryAccession": "O94927", "text": "This is HAUS augmin-like complex subunit 5 protein, from Human, contains 633 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94927", "organism_name": "Human", "protein_name": "HAUS augmin-like complex subunit 5", "length": 633, "firstPublicDate": "2005-06-07", "FUNCTION": "Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the HAUS5 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MELAQEARELGCWAVEEMGVPVAARAPESTLRRLCLGQGADIWAYILQHVHSQRTVKKIRGNLLWYGHQDSPQVRRKLELEAAVTRLRAEIQELDQSLELMERDTEAQDTAMEQARQHTQDTQRRALLLRAQAGAMRRQQHTLRDPMQRLQNQLRRLQDMERKAKVDVTFGSLTSAALGLEPVVLRDVRTACTLRAQFLQNLLLPQAKRGSLPTPHDDHFGTSYQQWLSSVETLLTNHPPGHVLAALEHLAAEREAEIRSLCSGDGLGDTEISRPQAPDQSDSSQTLPSMVHLIQEGWRTVGVLVSQRSTLLKERQVLTQRLQGLVEEVERRVLGSSERQVLILGLRRCCLWTELKALHDQSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRLCRSPGEVLALVQRKVVPTFEAVAPQSRELLRCLEEEVRHLPHILLGTLLRHRPGELKPLPTVLPSIHQLHPASPRGSSFIALSHKLGLPPGKASELLLPAAASLRQDLLLLQDQRSLWCWDLLHMKTSLPPGLPTQELLQIQASQEKQQKENLGQALKRLEKLLKQALERIPELQGIVGDWWEQPGQAALSEELCQGLSLPQWRLRWVQAQGALQKLCS", "length": 633, "molWeight": 71682, "crc64": "23D8746F2A81ABCB", "md5": "F247B8F7C62145F18518F8CEB3EBB45C"}}
{"primaryAccession": "O95232", "text": "This is Luc7-like protein 3 protein, from Human, contains 432 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O95232", "organism_name": "Human", "protein_name": "Luc7-like protein 3", "length": 432, "firstPublicDate": "2000-05-30", "FUNCTION": "Binds cAMP regulatory element DNA sequence, May play a role in RNA splicing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Luc7 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN", "length": 432, "molWeight": 51466, "crc64": "E75F55EC0137310C", "md5": "BAFD7631E71C55AEFC3A88E6F691DD5A"}}
{"primaryAccession": "O95445", "text": "This is Apolipoprotein M protein, from Human, contains 188 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O95445", "organism_name": "Human", "protein_name": "Apolipoprotein M", "length": 188, "firstPublicDate": "2001-09-26", "FUNCTION": "Probably involved in lipid transport, Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the calycin superfamily, Lipocalin family, Highly divergent", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFHQIWAALLYFYGIILNSIYQCPEHSQLTTLGVDGKEFPEVHLGQWYFIAGAAPTKEELATFDPVDNIVFNMAAGSAPMQLHLRATIRMKDGLCVPRKWIYHLTEGSTDLRTEGRPDMKTELFSSSCPGGIMLNETGQGYQRFLLYNRSPHPPEKCVEEFKSLTSCLDSKAFLLTPRNQEACELSNN", "length": 188, "molWeight": 21253, "crc64": "E4C35FEC32B7CB86", "md5": "7A5B8C141A3AB7C5CA2D87D968CE8A3C"}}
{"primaryAccession": "O95563", "text": "This is Mitochondrial pyruvate carrier 2 protein, from Human, contains 127 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O95563", "organism_name": "Human", "protein_name": "Mitochondrial pyruvate carrier 2", "length": 127, "firstPublicDate": "2002-09-19", "FUNCTION": "Mediates the uptake of pyruvate into mitochondria", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2,A,105) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKAKAHK", "length": 127, "molWeight": 14279, "crc64": "D82E5879AB2EEA68", "md5": "94A03E1A3D725C5798423A88A2F8E221"}}
{"primaryAccession": "O95684", "text": "This is Centrosomal protein 43 protein, from Human, contains 399 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O95684", "organism_name": "Human", "protein_name": "Centrosomal protein 43", "length": 399, "firstPublicDate": "2006-05-02", "FUNCTION": "Required for anchoring microtubules to the centrosomes (PubMed:16314388, PubMed:28659385), Required for ciliation (PubMed:28625565, PubMed:28659385)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CEP43 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAEGTVGGPLLLEVIRRCQQKEKGPTTGEGALDLSDVHSPPKSPEGKTSAQTTPSKIPRYKGQGKKKTSGQKAGDKKANDEANQSDTSVSLSEPKSKSSLHLLSHETKIGSFLSNRTLDGKDKAGLCPDEDDMEGDSFFDDPIPKPEKTYGLRKEPRKQAGSLASLSDAPPLKSGLSSLAGAPSLKDSESKRGNTVLKDLKLISDKIGSLGLGTGEDDDYVDDFNSTSHRSEKSEISIGEEIEEDLSVEIDDINTSDKLDDLTQDLTVSQLSDVADYLEDVA", "length": 399, "molWeight": 43065, "crc64": "7A4B65F627B9D272", "md5": "7C6C9C558F8C1A6D427F14BD64C3E81E"}}
{"primaryAccession": "O95747", "text": "This is Serine/threonine-protein kinase OSR1 protein, from Human, contains 527 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O95747", "organism_name": "Human", "protein_name": "Serine/threonine-protein kinase OSR1", "length": 527, "firstPublicDate": "2005-08-16", "FUNCTION": "Phosphorylates RELL1, RELL2 and RELT (PubMed:16389068, PubMed:28688764), Phosphorylates PAK1 (PubMed:14707132), Phosphorylates PLSCR1 in the presence of RELT (PubMed:22052202)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSEDSSALPWSINRDDYELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAEPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS", "length": 527, "molWeight": 58022, "crc64": "B46EC934E95A3A1F", "md5": "61404B3505964D63151CEA66C13373C8"}}
{"primaryAccession": "O95834", "text": "This is Echinoderm microtubule-associated protein-like 2 protein, from Human, contains 649 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O95834", "organism_name": "Human", "protein_name": "Echinoderm microtubule-associated protein-like 2", "length": 649, "firstPublicDate": "2001-10-18", "FUNCTION": "Tubulin binding protein that inhibits microtubule nucleation and growth, resulting in shorter microtubules", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the WD repeat EMAP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSFGAGKTKEVIFSVEDGSVKMFLRGRPVPMMIPDELAPTYSLDTRSELPSCRLKLEWVYGYRGRDCRANLYLLPTGEIVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAIHPDMVTIATGQVAGTTKEGKPLPPHVRIWDSVSLSTLHVLGLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHMLSVWDWAKETKVVDVKCSNEAVLVATFHPTDPTVLITCGKSHIYFWTLEGGSLSKRQGLFEKHEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNRITQAVLGAHDGGVFGLCALRDGTLVSGGGRDRRVVLWGSDYSKLQEVEVPEDFGPVRTVAEGHGDTLYVGTTRNSILQGSVHTGFSLLVQGHVEELWGLATHPSRAQFVTCGQDKLVHLWSSDSHQPLWSRIIEDPARSAGFHPSGSVLAVGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEILYWDPATCKQITSADAVRNMEWATATCVLGFGVFGIWSEGADGTDINAVARSHDGKLLASADDFGKVHLFSYPCCQPRALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVV", "length": 649, "molWeight": 70679, "crc64": "F356D3D974D208C9", "md5": "F47B4798204A5A987476A819711FB2A0"}}
{"primaryAccession": "O95926", "text": "This is Pre-mRNA-splicing factor SYF2 protein, from Human, contains 243 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O95926", "organism_name": "Human", "protein_name": "Pre-mRNA-splicing factor SYF2", "length": 243, "firstPublicDate": "2006-09-19", "FUNCTION": "Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SYF2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAIAASEVLVDSAEEGSLAAAAELAAQKREQRLRKFRELHLMRNEARKLNHQEVVEEDKRLKLPANWEAKKARLEWELKEEEKKKECAARGEDYEKVKLLEISAEDAERWERKKKRKNPDLGFSDYAAAQLRQYHRLTKQIKPDMETYERLREKHGEEFFPTSNSLLHGTHVPSTEEIDRMVIDLEKQIEKRDKYSRRRPYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTAV", "length": 243, "molWeight": 28722, "crc64": "6F910C13BC09A7F7", "md5": "E81D407A069CC5E71E88D2E39424C404"}}
{"primaryAccession": "O95931", "text": "This is Chromobox protein homolog 7 protein, from Human, contains 251 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O95931", "organism_name": "Human", "protein_name": "Chromobox protein homolog 7", "length": 251, "firstPublicDate": "2001-08-29", "FUNCTION": "Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development, PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility, Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3), Binds to trimethylated lysine residues in histones, and possibly also other proteins, Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKAGAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAPDVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAAEGFFRDRSGKF", "length": 251, "molWeight": 28341, "crc64": "A90019C1D08812B8", "md5": "0F6A06160E50458549C5A5845CB472E4"}}
{"primaryAccession": "O96693", "text": "This is 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic protein, from Plasmodium falciparum (isolate HB3), contains 488 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O96693", "organism_name": "Plasmodium falciparum (isolate HB3)", "protein_name": "1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic", "length": 488, "firstPublicDate": "2012-02-22", "FUNCTION": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the DXR family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKKYIYIYFFFITITINDLVINNTSKCVSIERRKNNAYINYGIGYNGPDNKITKSRRCKRIKLCKKDLIDIGAIKKPINVAIFGSTGSIGTNALNIIRECNKIENVFNVKALYVNKSVNELYEQAREFLPEYLCIHDKSVYEELKELVKNIKDYKPIILCGDEGMKEICSSNSIDKIVIGIDSFQGLYSTMYAIMNNKIVALANKESIVSAGFFLKKLLNIHKNAKIIPVDSEHSAIFQCLDNNKVLKTKCLQDNFSKINNINKIFLCSSGGPFQNLTMDELKNVTSENALKHPKWKMGKKITIDSATMMNKGLEVIETHFLFDVDYNDIEVIVHKECIIHSCVEFIDKSVISQMYYPDMQIPILYSLTWPDRIKTNLKPLDLAQVSTLTFHKPSLEHFPCIKLAYQAGIKGNFYPTVLNASNEIANNLFLNNKIKYFDISSIISQVLESFNSQKVSENSEDLMKQILQIHSWAKDKATDIYNKHNSS", "length": 488, "molWeight": 55757, "crc64": "4E280C81CDFAD3EF", "md5": "31724E9FECF636DF2788F00B9A835EA1"}}
{"primaryAccession": "O97859", "text": "This is Sialidase-3 protein, from Bovine, contains 428 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O97859", "organism_name": "Bovine", "protein_name": "Sialidase-3", "length": 428, "firstPublicDate": "2001-11-16", "FUNCTION": "Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides, Displays high catalytic efficiency for gangliosides including alpha-(2->3)-sialylated GD1a and GM3 and alpha-(2->8)-sialylated GD3 (PubMed:9988745), Plays a role in the regulation of transmembrane signaling through the modulation of ganglioside content of the lipid bilayer and by direct interaction with signaling receptors, such as EGFR, Desialylates EGFR and activates downstream signaling in proliferating cells, Contributes to clathrin-mediated endocytosis by regulating sorting of endocytosed receptors to early and recycling endosomes (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glycosyl hydrolase 33 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEEVTSCSFSSPLFQQEDKRGVTYRIPALIYVPPAHTFLAFAEKRSSSKDEDALHLVLRRGLRTGQSVQWEPLKSLMKATLPGHRTMNPCPVWERKSGYVYLFFICVQGHVTERQQIMSGRNPARLCFICSQDAGYSWSDVRDLTEEVIGPEVTHWATFAVGPGHGIQLQSGRLIIPAYAYYIPFWFFCFRLPYRARPHSLMIYSDDLGATWHHGRLIKPMVTVECEVAEVIGKAGHPVLYCSARTPNRHRAEALSIDHGECFQKPVLSHQLCEPPHGCQGSVVSFCPLEIPGGCQDLAGEDAPAIQQSPLLCSSVRPEPEAGTLSESWLLYSHPTNKKRRVDLGIYLNQSPLEAACWSRPWILHCGPCGYSDLAALENEGLFGCLFECGTKQECEQIAFRLFTDREILSHVQGDCSTPGMNSEPSKK", "length": 428, "molWeight": 47917, "crc64": "418B34F3245A8F21", "md5": "9702444A1170FDFC10EAF41112544D59"}}
{"primaryAccession": "P00927", "text": "This is Threonine dehydratase, mitochondrial protein, from Baker's yeast, contains 576 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00927", "organism_name": "Baker's yeast", "protein_name": "Threonine dehydratase, mitochondrial", "length": 576, "firstPublicDate": "1986-07-21", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the serine/threonine dehydratase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSATLLKQPLCTVVRQGKQSKVSGLNLLRLKAHLHRQHLSPSLIKLHSELKLDELQTDNTPDYVRLVLRSSVYDVINESPISQGVGLSSRLNTNVILKREDLLPVFSFKLRGAYNMIAKLDDSQRNQGVIACSAGNHAQGVAFAAKHLKIPATIVMPVCTPSIKYQNVSRLGSQVVLYGNDFDEAKAECAKLAEERGLTNIPPFDHPYVIAGQGTVAMEILRQVRTANKIGAVFVPVGGGGLIAGIGAYLKRVAPHIKIIGVETYDAATLHNSLQRNQRTPLPVVGTFADGTSVRMIGEETFRVAQQVVDEVVLVNTDEICAAVKDIFEDTRSIVEPSGALSVAGMKKYISTVHPEIDHTKNTYVPILSGANMNFDRLRFVSERAVLGEGKEVFMLVTLPDVPGAFKKMQKIIHPRSVTEFSYRYNEHRHESSSEVPKAYIYTSFSVVDREKEIKQVMQQLNALGFEAVDISDNELAKSHGRYLVGGASKVPNERIISFEFPERPGALTRFLGGLSDSWNLTLFHYRNHGADIGKVLAGISVPPRENLTFQKFLEDLGYTYHDETDNTVYQKFLKY", "length": 576, "molWeight": 63831, "crc64": "0801BCBD7EEDDC1F", "md5": "E0E00EAED14CB18B747C39A9C0A50A6B"}}
{"primaryAccession": "P01040", "text": "This is Cystatin-A protein, from Human, contains 98 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P01040", "organism_name": "Human", "protein_name": "Cystatin-A", "length": 98, "firstPublicDate": "1986-07-21", "FUNCTION": "This is an intracellular thiol proteinase inhibitor, Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the cystatin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIPGGLSEAKPATPEIQEIVDKVKPQLEEKTNETYGKLEAVQYKTQVVAGTNYYIKVRAGDNKYMHLKVFKSLPGQNEDLVLTGYQVDKNKDDELTGF", "length": 98, "molWeight": 11006, "crc64": "2F5F0D61C91305EE", "md5": "0A5E0CBA9FE2C313E616CB6BD95612D6"}}
{"primaryAccession": "P01096", "text": "This is ATPase inhibitor, mitochondrial protein, from Bovine, contains 109 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P01096", "organism_name": "Bovine", "protein_name": "ATPase inhibitor, mitochondrial", "length": 109, "firstPublicDate": "1986-07-21", "FUNCTION": "Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix, Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase (PubMed:10831597, PubMed:12923572, PubMed:17895376, PubMed:18687699, PubMed:21192948, PubMed:7397110), Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the ATPase inhibitor family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAATALAARTRQAVWSVWAMQGRGFGSESGDNVRSSAGAVRDAGGAFGKREQAEEERYFRARAKEQLAALKKHHENEISHHAKEIERLQKEIERHKQSIKKLKQSEDDD", "length": 109, "molWeight": 12301, "crc64": "0F8816DECCAABA7E", "md5": "958F807F156F27F0E36A113D9CB93403"}}
{"primaryAccession": "P01143", "text": "This is Corticoliberin protein, from Rat, contains 187 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P01143", "organism_name": "Rat", "protein_name": "Corticoliberin", "length": 187, "firstPublicDate": "1986-07-21", "FUNCTION": "Hormone regulating the release of corticotropin from pituitary gland (PubMed:6603620), Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRLRLLVSAGMLLVALSPCLPCRALLSRGSVSGAPRAPQPLNFLQPEQPQQPQPILIRMGEEYFLRLGNLNRSPAARLSPNSTPLTAGRGSRPSHDQAAANFFRVLLQQLQMPQRPLDSSTELAERGAEDALGGHQGALERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK", "length": 187, "molWeight": 20680, "crc64": "911602C82A444CFB", "md5": "6178BD64DF25743ECD5BEBB8C877D094"}}
{"primaryAccession": "P02655", "text": "This is Apolipoprotein C-II protein, from Human, contains 101 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P02655", "organism_name": "Human", "protein_name": "Apolipoprotein C-II", "length": 101, "firstPublicDate": "1986-07-21", "FUNCTION": "Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma, Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase, Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase, In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the apolipoprotein C2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGTRLLPALFLVLLVLGFEVQGTQQPQQDEMPSPTFLTQVKESLSSYWESAKTAAQNLYEKTYLPAVDEKLRDLYSKSTAAMSTYTGIFTDQVLSVLKGEE", "length": 101, "molWeight": 11284, "crc64": "51CB86FEDB174D84", "md5": "E2C6D4144B5CBDC78F5E846512C8533C"}}
{"primaryAccession": "P02724", "text": "This is Glycophorin-A protein, from Human, contains 150 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P02724", "organism_name": "Human", "protein_name": "Glycophorin-A", "length": 150, "firstPublicDate": "1986-07-21", "FUNCTION": "Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane (PubMed:35835865), Glycophorin A is the major intrinsic membrane protein of the erythrocyte, The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors, Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1, May be involved in translocation of SLC4A1 to the plasma membrane, Is a receptor for influenza virus, Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans, Appears to be a receptor for Hepatitis A virus (HAV)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glycophorin A family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MYGKIIFVLLLSEIVSISASSTTGVAMHTSTSSSVTKSYISSQTNDTHKRDTYAATPRAHEVSEISVRTVYPPEEETGERVQLAHHFSEPEITLIIFGVMAGVIGTILLISYGIRRLIKKSPSDVKPLPSPDTDVPLSSVEIENPETSDQ", "length": 150, "molWeight": 16331, "crc64": "48A5450E22FA99C9", "md5": "8B29D15A771679C2FF950CABE13E3D45"}}
{"primaryAccession": "P02730", "text": "This is Band 3 anion transport protein protein, from Human, contains 911 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P02730", "organism_name": "Human", "protein_name": "Band 3 anion transport protein", "length": 911, "firstPublicDate": "1986-07-21", "FUNCTION": "(Microbial infection) Acts as a receptor for P,falciparum (isolate 3D7) MSP9 and thus, facilitates merozoite invasion of erythrocytes", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the anion exchanger (TC 2,A,31) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGAWGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGVKPAVLTRSGDPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAVELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRELLRRRYQSSPAKPDSSFYKGLDLNGGPDDPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTYNYNVLMVPKPQGPLPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMPV", "length": 911, "molWeight": 101792, "crc64": "35EC3EE7AFF27D2F", "md5": "0FC0B14AB719AFFA50E864FF42E7B0F1"}}
{"primaryAccession": "P02835", "text": "This is Segmentation protein fushi tarazu protein, from Fruit fly, contains 410 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P02835", "organism_name": "Fruit fly", "protein_name": "Segmentation protein fushi tarazu", "length": 410, "firstPublicDate": "1986-07-21", "FUNCTION": "May play a role in determining neuronal identity, may be directly involved in specifying identity of individual neurons, Required during embryogenesis for the process of body segmentation, Homeotic protein, required in alternating segment primordia, it specifies the correct number of segments", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Antp homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATTNSQSHYSYADNMNMYNMYHPHSLPPTYYDNSGSNAYYQNTSNYQGYYPQESYSESCYYYNNQEQVTTQTVPPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQTQKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPVPMYHHHQTTAAYPAYSHSHSHGYGLLNDYPQQQTHQQYDAYPQQYQHQCSYQQHPQDLYHLS", "length": 410, "molWeight": 46479, "crc64": "517154F3DAF8262F", "md5": "5CA6C084005F9068FEF40E8F828C12C5"}}
{"primaryAccession": "P02836", "text": "This is Segmentation polarity homeobox protein engrailed protein, from Fruit fly, contains 552 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P02836", "organism_name": "Fruit fly", "protein_name": "Segmentation polarity homeobox protein engrailed", "length": 552, "firstPublicDate": "1986-07-21", "FUNCTION": "This protein specifies the body segmentation pattern, It is required for the development of the central nervous system, Transcriptional regulator that represses activated promoters, Wg signaling operates by inactivating the SGG repression of EN autoactivation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the engrailed homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALEDRCSPQSAPSPITLQMQHLHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQLAAGVFHHPAMAFDAAAAAAAAAAAAAAHAHAAALQQRLSGSGSPASCSTPASSTPLTIKEEESDSVIGDMSFHNQTHTTNEEEEAEEDDDIDVDVDDTSAGGRLPPPAHQQQSTAKPSLAFSISNILSDRFGDVQKPGKSMENQASIFRPFEASRSQTATPSAFTRVDLLEFSRQQQAAAAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEELEMRMNGQIP", "length": 552, "molWeight": 59411, "crc64": "92A94C14AA85C527", "md5": "A8E717CA8902CEC398EE9A54263B1E7E"}}
{"primaryAccession": "P03973", "text": "This is Antileukoproteinase protein, from Human, contains 132 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P03973", "organism_name": "Human", "protein_name": "Antileukoproteinase", "length": 132, "firstPublicDate": "1986-10-23", "FUNCTION": "Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G (PubMed:3533531, PubMed:3462719, PubMed:2039600, PubMed:2110563, PubMed:10702419, PubMed:24121345), Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L,major, Down-regulates responses to bacterial lipopolysaccharide (LPS) (By similarity), Plays a role in regulating the activation of NF-kappa-B and inflammatory responses (PubMed:10702419, PubMed:24352879), Has antimicrobial activity against mycobacteria, but not against salmonella, Contributes to normal resistance against infection by M,tuberculosis, Required for normal resistance to infection by L,major, Required for normal wound healing, probably by preventing tissue damage by limiting protease activity (By similarity), Together with ELANE, required for normal differentiation and proliferation of bone marrow myeloid cells (PubMed:24352879)", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGKKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMGMCGKSCVSPVKA", "length": 132, "molWeight": 14326, "crc64": "B62F3221E0903D90", "md5": "33DB29107983282B08DE6D0FDBCDD95C"}}
{"primaryAccession": "P04201", "text": "This is Proto-oncogene Mas protein, from Human, contains 325 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P04201", "organism_name": "Human", "protein_name": "Proto-oncogene Mas", "length": 325, "firstPublicDate": "1987-03-20", "FUNCTION": "Receptor for angiotensin 1-7 (By similarity), Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels, Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade, The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDGSNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSRNDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRLLYLLYYEYWSTFGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLTRAFKDEMQPRRQKDNCNTVTVETVV", "length": 325, "molWeight": 37465, "crc64": "3368E7B174744B83", "md5": "A239CFEBDE6CC0D37BCE2FEF240C3F97"}}
{"primaryAccession": "P04913", "text": "This is Histone H2B-alpha protein, from Fission yeast, contains 126 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P04913", "organism_name": "Fission yeast", "protein_name": "Histone H2B-alpha", "length": 126, "firstPublicDate": "1987-08-13", "FUNCTION": "Core component of nucleosome, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2B family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSAAEKKPASKAPAGKAPRDTMKSADKKRGKNRKETYSSYIYKVLKQVHPDTGISNQAMRILNSFVNDIFERIATEASKLAAYNKKSTISSREIQTAVRLILPGELAKHAVTEGTKSVTKYSSSAQ", "length": 126, "molWeight": 13819, "crc64": "64A02B9AFE7414E3", "md5": "A58E1A8C2BAC5F5CCD65409372FCC350"}}
{"primaryAccession": "P04919", "text": "This is Band 3 anion transport protein protein, from Mouse, contains 929 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P04919", "organism_name": "Mouse", "protein_name": "Band 3 anion transport protein", "length": 929, "firstPublicDate": "1987-08-13", "FUNCTION": "Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein, Component of the ankyrin-1 complex of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin, Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane, Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the anion exchanger (TC 2,A,31) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGDMRDHEEVLEIPDRDSEEELENIIGQIAYRDLTIPVTEMQDPEALPTEQTATDYVPSSTSTPHPSSGQVYVELQELMMDQRNQELQWVEAAHWIGLEENLREDGVWGRPHLSYLTFWSLLELQKVFSKGTFLLGLAETSLAGVANHLLDCFIYEDQIRPQDREELLRALLLKRSHAEDLGNLEGVKPAVLTRSGGASEPLLPHQPSLETQLYCGQAEGGSEGPSTSGTLKIPPDSETTLVLVGRANFLEKPVLGFVRLKEAVPLEDLVLPEPVGFLLVLLGPEAPHVDYTQLGRAAATLMTERVFRITASMAHNREELLRSLESFLDCSLVLPPTDAPSEKALLNLVPVQKELLRRRYLPSPAKPDPNLYNTLDLNGGKGGPGDEDDPLRRTGRIFGGLIRDIRRRYPYYLSDITDALSPQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFFSFCESNNLEYIVGRAWIGFWLILLVMLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIFQDYPLQQTYAPVVMKPKPQGPVPNTALFSLVLMAGTFLLAMTLRKFKNSTYFPGKLRRVIGDFGVPISILIMVLVDSFIKGTYTQKLSVPDGLKVSNSSARGWVIHPLGLYRLFPTWMMFASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASGPGAAAQIQEVKEQRISGLLVSVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRLILPLIFRELELQCLDGDDAKVTFDEENGLDEYDEVPMPV", "length": 929, "molWeight": 103136, "crc64": "5C0E281C394FB614", "md5": "007D106AEBCB334360DA25ED76AD44A7"}}
{"primaryAccession": "P05166", "text": "This is Propionyl-CoA carboxylase beta chain, mitochondrial protein, from Human, contains 539 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P05166", "organism_name": "Human", "protein_name": "Propionyl-CoA carboxylase beta chain, mitochondrial", "length": 539, "firstPublicDate": "1987-08-13", "FUNCTION": "This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites (PubMed:6765947, PubMed:15890657), Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (PubMed:6765947, PubMed:15890657), Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity), Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA at a much lower rate (PubMed:6765947), Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the AccD/PCCB family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAALRVAAVGARLSVLASGLRAAVRSLCSQATSVNERIENKRRTALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFVESDMFVEHRCADFGMAADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFFNYLPLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDEREFFEIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGDTNYAWPTAEIAVMGAKGAVEIIFKGHENVEAAQAEYIEKFANPFPAAVRGFVDDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL", "length": 539, "molWeight": 58216, "crc64": "A2DAAC00312D3C0F", "md5": "352E60244C907B1B380E36982AE5CCED"}}
{"primaryAccession": "P05186", "text": "This is Alkaline phosphatase, tissue-nonspecific isozyme protein, from Human, contains 524 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P05186", "organism_name": "Human", "protein_name": "Alkaline phosphatase, tissue-nonspecific isozyme", "length": 524, "firstPublicDate": "1987-08-13", "FUNCTION": "Alkaline phosphatase that metabolizes various phosphate compounds and plays a key role in skeletal mineralization and adaptive thermogenesis (PubMed:12162492, PubMed:23688511, PubMed:25982064), Has broad substrate specificity and can hydrolyze a considerable variety of compounds: however, only a few substrates, such as diphosphate (inorganic pyrophosphate; PPi), pyridoxal 5'-phosphate (PLP) and N-phosphocreatine are natural substrates (PubMed:12162492, PubMed:2220817), Plays an essential role in skeletal and dental mineralization via its ability to hydrolyze extracellular diphosphate, a potent mineralization inhibitor, to phosphate: it thereby promotes hydroxyapatite crystal formation and increases inorganic phosphate concentration (PubMed:23688511, PubMed:25982064), Acts in a non-redundant manner with PHOSPHO1 in skeletal mineralization: while PHOSPHO1 mediates the initiation of hydroxyapatite crystallization in the matrix vesicles (MVs), ALPL/TNAP catalyzes the spread of hydroxyapatite crystallization in the extracellular matrix (By similarity), Also promotes dephosphorylation of osteopontin (SSP1), an inhibitor of hydroxyapatite crystallization in its phosphorylated state; it is however unclear whether ALPL/TNAP mediates SSP1 dephosphorylation via a direct or indirect manner (By similarity), Catalyzes dephosphorylation of PLP to pyridoxal (PL), the transportable form of vitamin B6, in order to provide a sufficient amount of PLP in the brain, an essential cofactor for enzymes catalyzing the synthesis of diverse neurotransmitters (PubMed:2220817, PubMed:20049532), Additionally, also able to mediate ATP degradation in a stepwise manner to adenosine, thereby regulating the availability of ligands for purinergic receptors (By similarity), Also capable of dephosphorylating microbial products, such as lipopolysaccharides (LPS) as well as other phosphorylated small-molecules, such as poly-inosine:cytosine (poly I:C) (PubMed:28448526), Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating hydrolysis of N-phosphocreatine to initiate a futile cycle of creatine dephosphorylation and phosphorylation (By similarity), During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the alkaline phosphatase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF", "length": 524, "molWeight": 57305, "crc64": "71B45F17F6211900", "md5": "001513C28B7D90DB9461B49D1B911D60"}}
{"primaryAccession": "P05549", "text": "This is Transcription factor AP-2-alpha protein, from Human, contains 437 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P05549", "organism_name": "Human", "protein_name": "Transcription factor AP-2-alpha", "length": 437, "firstPublicDate": "1989-07-01", "FUNCTION": "Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes, AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development, They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC, AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle, Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation, Associates with chromatin to the PITX2 P1 promoter region", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the AP-2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLWKLTDNIKYEDCEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNNAKSSDKEEKHRK", "length": 437, "molWeight": 48062, "crc64": "FB8FA33C3AEED71F", "md5": "BBA57AC412D6CA5CA97FE2FE5FBFCA66"}}
{"primaryAccession": "P05740", "text": "This is Large ribosomal subunit protein uL22A protein, from Baker's yeast, contains 184 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P05740", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein uL22A", "length": 184, "firstPublicDate": "1988-11-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the universal ribosomal protein uL22 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MARYGATSTNPAKSASARGSYLRVSFKNTRETAQAINGWELTKAQKYLEQVLDHQRAIPFRRFNSSIGRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAANAEAKGLDATKLYVSHIQVNQAPKQRRRTYRAHGRINKYESSPSHIELVVTEKEEAVAKAAEKKVVRLTSRQRGRIAAQKRIAA", "length": 184, "molWeight": 20549, "crc64": "B8902DD90714671D", "md5": "202CCA977C8C1ADA38A31AD0884399E0"}}
{"primaryAccession": "P05764", "text": "This is Small ribosomal subunit protein eS21 protein, from Fission yeast, contains 87 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P05764", "organism_name": "Fission yeast", "protein_name": "Small ribosomal subunit protein eS21", "length": 87, "firstPublicDate": "1988-11-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (By similarity), eS21 is required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits, Has a physiological role leading to 18S rRNA stability (PubMed:14623272)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS21 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MENEAGQLVDLYVPRKCSATNRIIQAKDHASVQINVCAVDAEGRQIPGEKTTYAISGFVRSKGESDDCINRLTTQDGLLEGVWSYQR", "length": 87, "molWeight": 9617, "crc64": "970F7B10DC348B6A", "md5": "8F2BE79364D3B4ABCA0478E54B871FBC"}}
{"primaryAccession": "P05981", "text": "This is Serine protease hepsin protein, from Human, contains 417 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P05981", "organism_name": "Human", "protein_name": "Serine protease hepsin", "length": 417, "firstPublicDate": "1988-11-01", "FUNCTION": "Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL (PubMed:21875933, PubMed:15839837), Plays a role in cell growth and maintenance of cell morphology (PubMed:8346233, PubMed:21875933), Plays a role in the proteolytic processing of ACE2 (PubMed:24227843), Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization (PubMed:26673890)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL", "length": 417, "molWeight": 45011, "crc64": "B2086FF661E551D7", "md5": "E095B0E949AE7746C72A1E52BA16BD0F"}}
{"primaryAccession": "P06103", "text": "This is Eukaryotic translation initiation factor 3 subunit B protein, from Baker's yeast, contains 763 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P06103", "organism_name": "Baker's yeast", "protein_name": "Eukaryotic translation initiation factor 3 subunit B", "length": 763, "firstPublicDate": "1988-01-01", "FUNCTION": "RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome, The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eIF-3 subunit B family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKNFLPRTLKNIYELYFNNISVHSIVSRNTQLKRSKIIQMTTETFEDIKLEDIPVDDIDFSDLEEQYKVTEEFNFDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTMKDVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQFVLQDDVKTSVFWNSMFNEEDSLVESRENWSTNYVRFSPKGTYLFSYHQQGVTAWGGPNFDRLRRFYHPDVRNSSVSPNEKYLVTFSTEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSPYLKWPLVRWSYNDKYCARMVGDSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQVSNVTLHWQNQAEFLCFNVERHTKSGKTQFSNLQICRLTERDIPVEKVELKDSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGEKNINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFNIAGNLVKEDIIAGFKNFAWRPRPASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDLILHQRELLKQWTEYREKIGQEMEKSMNFKIFDVQPEDASDDFTTIEEIVEEVLEETKEKVE", "length": 763, "molWeight": 88130, "crc64": "F5E4E783408EE948", "md5": "A26060534CCEDB464EB67B6E77754436"}}
{"primaryAccession": "P06296", "text": "This is Corticoliberin protein, from Pig, contains 191 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P06296", "organism_name": "Pig", "protein_name": "Corticoliberin", "length": 191, "firstPublicDate": "1988-01-01", "FUNCTION": "Hormone regulating the release of corticotropin from pituitary gland (PubMed:3878520), Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRLPLLVSAGVLLVALLPCPPCRALLSRGPVLGARQAPQHPQALDFLQPQQQPQQPQPRPVLLRMGEEYFLRLGNLNKSPAAPLSPASSPLTGSSGNRPDEVAANFFRALLQQLPLPRRPLDSPSGPAERGAENALSSRQEAPERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK", "length": 191, "molWeight": 20997, "crc64": "587E58F516AB9006", "md5": "DA560CFA4BD83CE20F377D759A244655"}}
{"primaryAccession": "P06400", "text": "This is Retinoblastoma-associated protein protein, from Human, contains 928 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P06400", "organism_name": "Human", "protein_name": "Retinoblastoma-associated protein", "length": 928, "firstPublicDate": "1988-01-01", "FUNCTION": "(Microbial infection) In case of viral infections, interactions with SV40 large T antigen, HPV E7 protein or adenovirus E1A protein induce the disassembly of RB1-E2F1 complex thereby disrupting RB1's activity", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the retinoblastoma protein (RB) family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQKLKIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTELQKNIEISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSSISTEINSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFMNSLGLVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKSNLDEEVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAEMTSTRTRMQKQKMNDSMDTSNKEEK", "length": 928, "molWeight": 106159, "crc64": "C8E746111E19CC32", "md5": "DD07F145658E8063A5DBFAAA0CA3590B"}}
{"primaryAccession": "P07250", "text": "This is Inositol polyphosphate multikinase protein, from Baker's yeast, contains 355 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P07250", "organism_name": "Baker's yeast", "protein_name": "Inositol polyphosphate multikinase", "length": 355, "firstPublicDate": "1988-04-01", "FUNCTION": "Inositol phosphate kinase with both monophosphoinositol and diphosphoinositol polyphosphate synthase activities, Able to phosphorylate inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) on both the carbon-3 and carbon-6 positions to synthesize inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4) and inositol 1,4,5,6-tetrakisphosphate (Ins(1,4,5,6)P4), and then to subsequently phosphorylate and convert either isomer of InsP4 to inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) (PubMed:10574768, PubMed:10683435, PubMed:11311242), Its predominant in vivo catalytic function is to convert Ins(1,4,5)P3 to Ins(1,4,5,6)P4 to Ins(1,3,4,5,6)P5 via 6- and 3-kinase activities (PubMed:15944147), It can also use Ins(1,3,4,5,6)P5 as a substrate and act as a diphosphoinositol polyphosphate synthase to generate two different isomers of PP-InsP4 (PubMed:11311242), Has also a role in transcription regulation, Forms a complex with ARG80, ARG81 and MCM1 (ArgR-MCM1), which coordinates the expression of arginine anabolic and catabolic genes in response to arginine, Recruits ARG80 and MCM21 to stabilize them (PubMed:3298999, PubMed:8043104, PubMed:10632874), Neither the kinase activity nor inositol phosphates are required for the formation of ArgR-MCM1 transcriptional complexes on DNA promoter elements and the control of arginine metabolism (PubMed:11119723, PubMed:10720331, PubMed:12828642, PubMed:22992733), In contrast, only the catalytic activity is required for PHO gene repression by phosphate and for NCR gene activation in response to nitrogen availability, indicating a role for inositol pyrophosphates in these controls (PubMed:12828642), Inositol polyphosphates may be involved in the regulation of chromatin remodeling of transcription (PubMed:12434012), Regulates nuclear mRNA export via inositol phosphate metabolism (PubMed:10390371, PubMed:10683435), Also has lipid kinase activity, transforming the lipid inositol phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) into phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) in the nucleus (PubMed:16123124), Its kinase activity is necessary for the propagation of most [PSI+] prion variants (PubMed:28923943)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the inositol phosphokinase (IPK) family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDTVNNYRVLEHKAAGHDGTLTDGDGLLIFKPAFPQELEFYKAIQVRDVSRRKSSADGDAPLCSWMPTYLGVLNEGAKIEQSGDAALLKIDERLSDSTDNLDSIPVKSEKSKQYLVLENLLYGFSKPNILDIKLGKTLYDSKASLEKRERMKRVSETTTSGSLGFRICGMKIQKNPSVLNQLSLEYYEEEADSDYIFINKLYGRSRTDQNVSDAIELYFNNPHLSDARKHQLKKTFLKRLQLFYNTMLEEEVRMISSSLLFIYEGDPERWELLNDVDKLMRDDFIDDDDDDDDNDDDDDDDAEGSSEGPKDKKTTGSLSSMSLIDFAHSEITPGKGYDENVIEGVETLLDIFMKF", "length": 355, "molWeight": 40353, "crc64": "F858B39E3C54E6BF", "md5": "9D3CE67AA2903B45C310B25971BD6C4C"}}
{"primaryAccession": "P07251", "text": "This is ATP synthase subunit alpha, mitochondrial protein, from Baker's yeast, contains 545 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P07251", "organism_name": "Baker's yeast", "protein_name": "ATP synthase subunit alpha, mitochondrial", "length": 545, "firstPublicDate": "1988-04-01", "FUNCTION": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain, F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk, During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation, Subunits alpha and beta form the catalytic core in F(1), Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits, Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the ATPase alpha/beta chains family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLARTAAIRSLSRTLINSTKAARPAAAALASTRRLASTKAQPTEVSSILEERIKGVSDEANLNETGRVLAVGDGIARVFGLNNIQAEELVEFSSGVKGMALNLEPGQVGIVLFGSDRLVKEGELVKRTGNIVDVPVGPGLLGRVVDALGNPIDGKGPIDAAGRSRAQVKAPGILPRRSVHEPVQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDTILNQKRWNNGSDESKKLYCVYVAVGQKRSTVAQLVQTLEQHDAMKYSIIVAATASEAAPLQYLAPFTAASIGEWFRDNGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSEKEGSGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKALKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLVRGERLTQLLKQNQYSPLATEEQVPLIYAGVNGHLDGIELSRIGEFESSFLSYLKSNHNELLTEIREKGELSKELLASLKSATESFVATF", "length": 545, "molWeight": 58608, "crc64": "E8041D289B924696", "md5": "AF0465400ED0FE4689FD92E7E7D96E24"}}
{"primaryAccession": "P07256", "text": "This is Cytochrome b-c1 complex subunit 1, mitochondrial protein, from Baker's yeast, contains 457 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P07256", "organism_name": "Baker's yeast", "protein_name": "Cytochrome b-c1 complex subunit 1, mitochondrial", "length": 457, "firstPublicDate": "1988-04-01", "FUNCTION": "Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation, The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase, The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol, In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the peptidase M16 family, UQCRC1/QCR1 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRTVTSKTVSNQFKRSLATAVATPKAEVTQLSNGIVVATEHNPSAHTASVGVVFGSGAANENPYNNGVSNLWKNIFLSKENSAVAAKEGLALSSNISRDFQSYIVSSLPGSTDKSLDFLNQSFIQQKANLLSSSNFEATKKSVLKQVQDFEENDHPNRVLEHLHSTAFQNTPLSLPTRGTLESLENLVVADLESFANNHFLNSNAVVVGTGNIKHEDLVNSIESKNLSLQTGTKPVLKKKAAFLGSEVRLRDDTLPKAWISLAVEGEPVNSPNYFVAKLAAQIFGSYNAFEPASRLQGIKLLDNIQEYQLCDNFNHFSLSYKDSGLWGFSTATRNVTMIDDLIHFTLKQWNRLTISVTDTEVERAKSLLKLQLGQLYESGNPVNDANLLGAEVLIKGSKLSLGEAFKKIDAITVKDVKAWAGKRLWDQDIAIAGTGQIEGLLDYMRIRSDMSMMRW", "length": 457, "molWeight": 50228, "crc64": "AE58739EFB695254", "md5": "50124E59082B948FEE5B8F4023D4D854"}}
{"primaryAccession": "P07313", "text": "This is Myosin light chain kinase 2, skeletal/cardiac muscle protein, from Rabbit, contains 608 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P07313", "organism_name": "Rabbit", "protein_name": "Myosin light chain kinase 2, skeletal/cardiac muscle", "length": 608, "firstPublicDate": "1988-04-01", "FUNCTION": "Implicated in the level of global muscle contraction and cardiac function (By similarity), Phosphorylates a specific serine in the N-terminus of a myosin light chain", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATENGAVELGIQSLSTDEASKGAASEESLAAEKDPAPPDPEKGPGPSDTKQDPDPSTPKKDANTPAPEKGDVVPAQPSAGGSQGPAGEGGQVEAPAEGSAGKPAALPQQTATAEASEKKPEAEKGPSGHQDPGEPTVGKKVAEGQAAARRGSPAFLHSPSCPAIIASTEKLPAQKPLSEASELIFEGVPATPGPTEPGPAKAEGGVDLLAESQKEAGEKAPGQADQAKVQGDTSRGIEFQAVPSERPRPEVGQALCLPAREEDCFQILDDCPPPPAPFPHRIVELRTGNVSSEFSMNSKEALGGGKFGAVCTCTEKSTGLKLAAKVIKKQTPKDKEMVMLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKEQGARMSAAQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV", "length": 608, "molWeight": 65468, "crc64": "9B2FD074165DADFE", "md5": "8892968D555D6ED101BFE6DED221A479"}}
{"primaryAccession": "P07664", "text": "This is Serendipity locus protein delta protein, from Fruit fly, contains 433 amino acids, has 7 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [194, 217], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [223, 245], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [251, 273], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [279, 301], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [308, 330], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [337, 359], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [405, 428], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "P07664", "organism_name": "Fruit fly", "protein_name": "Serendipity locus protein delta", "length": 433, "firstPublicDate": "1988-04-01", "FUNCTION": "Transcriptional activator that controls bicoid gene expression during oogenesis, Found in transcriptionally active cells, Binds to specific sites on polytene chromosomes of third instar larvae, Binds to the consensus DNA sequence 5'-YTAGAGATGGRAA-3'", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 7}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDTCFFCGAVDLSDTGSSSSMRYETLSAKVPSSQKTVSLVLTHLANCIQTQLDLKPGARLCPRCFQELSDYDTIMVNLMTTQKRLTTQLKGALKSEFEVPESGEDILVEEVEIPQSDVETDADAEADALFVELVKDQEESDTEIKREFVDEEEEEDDDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRVKQECTTCGKVYNSWYQLQKHISEEHSKQPNHICPICGVIRRDEEYLELHMNLHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICSICNVSFKSRKTFNHHTLIHKENRPRHYCSVCPKSFTERYTLKMHMKTHEGDVVYGVREEAPADEQQVVEELHVDVDESEAAVTVIMSDNDENSGFCLICNTNFENKKELEHHLQFDHDVVLK", "length": 433, "molWeight": 50028, "crc64": "9F89FB7696ECF3F7", "md5": "CD796428857878069CBB82FC1D4A379C"}}
{"primaryAccession": "P07766", "text": "This is T-cell surface glycoprotein CD3 epsilon chain protein, from Human, contains 207 amino acids, has 1 Ig-like Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [32, 112], "description": "Ig-like", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like Immunoglobulin domain"}], "meta_data": {"primaryAccession": "P07766", "organism_name": "Human", "protein_name": "T-cell surface glycoprotein CD3 epsilon chain", "length": 207, "firstPublicDate": "1988-08-01", "FUNCTION": "Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response, When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z, All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain, Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways (PubMed:2470098), In addition of this role of signal transduction in T-cell activation, CD3E plays an essential role in correct T-cell development, Initiates the TCR-CD3 complex assembly by forming the two heterodimers CD3D/CD3E and CD3G/CD3E, Participates also in internalization and cell surface down-regulation of TCR-CD3 complexes via endocytosis sequences present in CD3E cytosolic region (PubMed:10384095, PubMed:26507128)", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {"Ig-like Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQSGTHWRVLGLCLLSVGVWGQDGNEEMGGITQTPYKVSISGTTVILTCPQYPGSEILWQHNDKNIGGDEDDKNIGSDEDHLSLKEFSELEQSGYYVCYPRGSKPEDANFYLYLRARVCENCMEMDVMSVATIVIVDICITGGLLLLVYYWSKNRKAKAKPVTRGAGAGGRQRGQNKERPPPVPNPDYEPIRKGQRDLYSGLNQRRI", "length": 207, "molWeight": 23147, "crc64": "A1603D01CE9957D7", "md5": "DD7F414238B9CB3717A9FF777893BD39"}}
{"primaryAccession": "P08018", "text": "This is MAP kinase kinase PBS2 protein, from Baker's yeast, contains 668 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P08018", "organism_name": "Baker's yeast", "protein_name": "MAP kinase kinase PBS2", "length": 668, "firstPublicDate": "1988-08-01", "FUNCTION": "Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, Seems to phosphorylate HOG1 on a tyrosine residue", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEDKFANLSLHEKTGKSSIQLNEQTGSDNGSAVKRTSSTSSHYNNINADLHARVKAFQEQRALKRSASVGSNQSEQDKGSSQSPKHIQQIVNKPLPPLPVAGSSKVSQRMSSQVVQASSKSTLKNVLDNQETQNITDVNINIDTTKITATTIGVNTGLPATDITPSVSNTASATHKAQLLNPNRRAPRRPLSTQHPTRPNVAPHKAPAIINTPKQSLSARRGLKLPPGGMSLKMPTKTAQQPQQFAPSPSNKKHIETLSNSKVVEGKRSNPGSLINGVQSTSTSSSTEGPHDTVGTTPRTGNSNNSSNSGSSGGGGLFANFSKYVDIKSGSLNFAGKLSLSSKGIDFSNGSSSRITLDELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWLVKYRNQDVHMSEYITERLERRNKILRERGENGLSKNVPALHMGGL", "length": 668, "molWeight": 72720, "crc64": "9BC3435BDAFE8019", "md5": "2725C74102431F78E5B5C78FC99109A8"}}
{"primaryAccession": "P08985", "text": "This is Histone H2A.v protein, from Fruit fly, contains 141 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P08985", "organism_name": "Fruit fly", "protein_name": "Histone H2A.v", "length": 141, "firstPublicDate": "1988-11-01", "FUNCTION": "Variant histone H2A which replaces conventional H2A in a subset of nucleosomes, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repressive state of homeotic genes of the animal throughout development, Required for histone H3 'Lys-9' methylation and histone H4 'Lys-12' acetylation, two modifications that are essential for heterochromatin formation, Also involved in DNA double strand break (DSB) repair, Essential for early development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKEETVQDPQRKGNVILSQAY", "length": 141, "molWeight": 14981, "crc64": "0DA41C01F831A5B6", "md5": "676BF5E5C89AB8FB7409C747B9E0392D"}}
{"primaryAccession": "P08992", "text": "This is Histone H2A.Z protein, from Tetrahymena thermophila (strain SB210), contains 146 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P08992", "organism_name": "Tetrahymena thermophila (strain SB210)", "protein_name": "Histone H2A.Z", "length": 146, "firstPublicDate": "1988-11-01", "FUNCTION": "Variant histone H2A which replaces conventional H2A in a subset of nucleosomes, preferentially in transcriptionally active chromatin, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, Essential for vegetative growth", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGGKGGKGGKGGKGGKVGGAKNKKTPQSRSYKAGLQFPVGRIHRFLKGRVSAKNRVGATAAVYAAAILEYLTAEVLELAGNASKDFKVRRITPRHLLLAIRGDEELDILIKATIAGGGVIPHIHKALLGKHSTKNRSSAKTAEPR", "length": 146, "molWeight": 15315, "crc64": "5143E5DC0C60B517", "md5": "EA1E02858477CAB90D3979A11662C9E8"}}
{"primaryAccession": "P0C0S6", "text": "This is Histone H2A.Z protein, from Mouse, contains 128 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C0S6", "organism_name": "Mouse", "protein_name": "Histone H2A.Z", "length": 128, "firstPublicDate": "2005-12-06", "FUNCTION": "Variant histone H2A which replaces conventional H2A in a subset of nucleosomes, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, May be involved in the formation of constitutive heterochromatin, May be required for chromosome segregation during cell division, Essential for early development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128, "molWeight": 13553, "crc64": "E024E53818230371", "md5": "3701D01A00F7FC73BCF6692A4F8E67E2"}}
{"primaryAccession": "P0C0T4", "text": "This is Small ribosomal subunit protein eS25B protein, from Baker's yeast, contains 108 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C0T4", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS25B", "length": 108, "firstPublicDate": "1988-04-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS25 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPPKQQLSKAAKAAAALAGGKKSKKKWSKKSMKDRAQHAVILDQEKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYTRAAASE", "length": 108, "molWeight": 12009, "crc64": "C52D0334AEA125B5", "md5": "89FC6274FEAC428F1915C144602ECBF8"}}
{"primaryAccession": "P0C0V8", "text": "This is Small ribosomal subunit protein eS21A protein, from Baker's yeast, contains 87 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C0V8", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS21A", "length": 87, "firstPublicDate": "2005-12-20", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102), eS21 is required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits, Has a physiological role leading to 18S rRNA stability (PubMed:14627813)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS21 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MENDKGQLVELYVPRKCSATNRIIKADDHASVQINVAKVDEEGRAIPGEYVTYALSGYVRSRGESDDSLNRLAQNDGLLKNVWSYSR", "length": 87, "molWeight": 9746, "crc64": "52E1C24744E24F80", "md5": "6BEEE93D63A842DB591823EC2E6011B7"}}
{"primaryAccession": "P0C0X0", "text": "This is Small ribosomal subunit protein eS28B protein, from Baker's yeast, contains 67 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C0X0", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS28B", "length": 67, "firstPublicDate": "1986-07-21", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS28 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDSKTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR", "length": 67, "molWeight": 7565, "crc64": "ABF5A8353F18A641", "md5": "231243A4C10028983699584B2CEB6082"}}
{"primaryAccession": "P0C1Z0", "text": "This is Fasciculin-2 protein, from Eastern green mamba, contains 61 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C1Z0", "organism_name": "Eastern green mamba", "protein_name": "Fasciculin-2", "length": 61, "firstPublicDate": "2006-10-17", "FUNCTION": "Interferes with neuromuscular transmission by inhibiting the enzyme acetylcholinesterase (AChE) present at the neuromuscular junction, It selectively binds and inhibits with a 1:1 stoichiometry the mammalian and electric fish AChE at picomolar concentrations, It is highly specific for the peripheral site of AChE and blocks the entry of acetylcholine into the active site of the enzyme (through the Met-33 residue), thereby preventing its breakdown, It has been called fasciculin since after injection into mice it causes severe, generalized and long-lasting (5-7 hours) fasciculations", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the snake three-finger toxin family, Short-chain subfamily, Acn-esterase inhibitor sub-subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDNLEVKCCTSPDKCNY", "length": 61, "molWeight": 6758, "crc64": "50A38EF3633C383F", "md5": "BE74BE0E66CA7B4603630A5A17FEF2A4"}}
{"primaryAccession": "P0C606", "text": "This is SAGA-associated factor 29 protein, from Rat, contains 293 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C606", "organism_name": "Rat", "protein_name": "SAGA-associated factor 29", "length": 293, "firstPublicDate": "2008-01-15", "FUNCTION": "Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes (By similarity), SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3) (By similarity), In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me (By similarity), Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival (By similarity), Also binds non-histone proteins that are methylated on Lys residues: specifically recognizes and binds CGAS monomethylated on 'Lys-491' (By similarity), May be involved in MYC-mediated oncogenic transformation (PubMed:17334388)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SGF29 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALVSADSRIAELLTELHQLIKQTQEERSRSEHNLVNIQKTHERMQTENKISPYYRTKLRGLYTTAKADAEAECNILRKALDKIAEIKSLLEERRIAAKIAGLYNDSEPPRKTMRRGVLMTLLQQSAMTLPLWIGKPGDKPPPLCGAIPASGDYVAKPGDKVAARVKAVEGDEQWILAEVVSYSHATNKYEVDDIDEEGKERHTLSRRRIIPLPQWKANPETDPEALFQKEQLVLALYPQTTCFYRALIHTPPQRPQDDYSVLFEDTSYADGYSPPLNVAQRYVVACKEPKKK", "length": 293, "molWeight": 33268, "crc64": "52D0E6F27AA89580", "md5": "DA9DA5304EDBABD769E6D5E148566D83"}}
{"primaryAccession": "P0C7P3", "text": "This is Protein SLFN14 protein, from Human, contains 912 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C7P3", "organism_name": "Human", "protein_name": "Protein SLFN14", "length": 912, "firstPublicDate": "2008-07-01", "FUNCTION": "Displays polysome-associated endoribonuclease activity towards mRNAs and rRNAs (PubMed:25996083), May play a role in RNA surveillance pathways by recognizing stalled ribosomes and triggering endonucleolytic cleavage of aberrant mRNAs (Probable), Cleaves different types of rRNAs and mRNAs in a magnesium- and manganese-dependent and ATP-independent manner (By similarity), Involved in correct maturation of megakaryocytes and especially important for proplatelet extension", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Schlafen family, Subgroup III subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MESLKTDTEMPYPEVIVDVGRVIFGEENRKKMTNSCLKRSENSRIIRAICALLNSGGGVIKAEIDDKTYSYQCHGLGQDLETSFQKLLPSGSQKYLDYMQQGHNLLIFVKSWSPDVFSLPLRICSLRSNLYRRDVTSAINLSASSALELLREKGFRAQRGRPRVKKLHPQQVLNRCIQEEEDMRILASEFFKKDKLMYKEKLNFTESTHVEFKRFTTKKVIPRIKEMLPHYVSAFANTQGGYVLIGVDDKSKEVVGCKWEKVNPDLLKKEIENCIEKLPTFHFCCEKPKVNFTTKILNVYQKDVLDGYVCVIQVEPFCCVVFAEAPDSWIMKDNSVTRLTAEQWVVMMLDTQSAPPSLVTDYNSCLISSASSARKSPGYPIKVHKFKEALQRHLFPVTQEEVQFKPESLCKKLFSDHKELEGLMKTLIHPCSQGIVIFSRSWAGDVGFRKEQNVLCDALLIAVNSPVVLYTILIDPNWPGGLEYARNTAHQLKQKLQTVGGYTGKVCIIPRLIHLSSTQSRPGEIPLRYPRSYRLADEEEMEDLLQALVVVSLSSRSLLSDQMGCEFFNLLIMEQSQLLSESLQKTRELFIYCFPGVRKTALAIKIMEKIKDLFHCKPKEILYVCESDSLKDFVTQQTTCQAVTRKTFMQGEFLKIKHIVMDETENFCSKYGNWYMKAKNITHPKAKGTGSENLHHGILWLFLDPFQIHHADVNGLPPPSAQFPRKTITSGIHCALEIAKVMKEEMKRIKENPPSNMSPDTLALFSETAYEEATCAQALPGVCETKTNLTTEQIANYVARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLALLKAMELIETHRPSEVVFSPATGVWGSHIVLDSIQQFSGLERTVVFGLSPECDQSEEFHKLCFASRAIKHLYLLYEKRAAY", "length": 912, "molWeight": 103907, "crc64": "391054668F58FFAB", "md5": "F045D8953C6D59A629B5CBC811769271"}}
{"primaryAccession": "P0CB20", "text": "This is Con-ikot-ikot protein, from Striated cone, contains 123 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CB20", "organism_name": "Striated cone", "protein_name": "Con-ikot-ikot", "length": 123, "firstPublicDate": "2009-07-28", "FUNCTION": "Potently and selectively blocks the desensitization of ionotropic glutamate AMPA receptors (GRIA1, GRIA2, GRIA3 and GRIA4) (PubMed:19481459, PubMed:35377397), Binds to a different site than does the drug cyclothiazide (PubMed:19481459), The toxin acts like a straitjacket on the 'gating ring' of the ligand-binding domain (LBD) of the receptor (PubMed:25103405), It does so by restraining the domains via both intra- and interdimer cross-links such that agonist-induced closure of the LBD 'clamshells' is transduced into an irislike expansion of the gating ring (PubMed:25103405), Compared to other desensitization blockers, it is a poor stabilizer of the open channel because toxin-bound AMPA receptors undergo frequent brief closures (PubMed:35377397), In vitro, application of the toxin to hippocampal slices causes a large and rapid increase in resting AMPA receptor-mediated current leading to neuronal death (PubMed:19481459)", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAMNMSMTLCMFVMVVVAATVIDSTQLQEPDLSRMRRSGPADCCRMKECCTDRVNECLQRYSGREDKFVSFCYQEATVTCGSFNEIVGCCYGYQMCMIRVVKPNSLSGAHEACKTVSCGNPCA", "length": 123, "molWeight": 13635, "crc64": "61F0E44BDE2191D1", "md5": "E6614643B163A185786927767930C0B6"}}
{"primaryAccession": "P0CG03", "text": "This is Thrombin-like enzyme bhalternin protein, from Urutu, contains 260 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CG03", "organism_name": "Urutu", "protein_name": "Thrombin-like enzyme bhalternin", "length": 260, "firstPublicDate": "2010-06-15", "FUNCTION": "Thrombin-like snake venom serine protease that induces blood clotting in vitro, defibrinogenation in vivo (by intraperitoneal injection into mice), albuminolytic and fibrinogenolytic activities, Preferentially cleaves the alpha chain of fibrinogen (FGA), Causes hemolysis in the heart, causes apparent hyperemia and lymphocytic interstitial pneumonitis in the lung, causes necrosis and inflammatory infiltrate in the liver, and causes glomerular congestion in the kidney, Also provokes a drastic myonecrosis", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Snake venom subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVLIRVLANLLILQLSYAQKASELVIGGDECNINEHRSLVVLFNSSGFLCAGTLINQEWVLTAANCDRKNIRIKLGMHSKNVTNEDEQTRVPKRSTFVSVAKTSHQTLGTRTSMLIRLKRPVNDSPHIAPLSLPSSPPSVGSVCRVMGWGTISPTKVSYPDVPHCANINLLDYEVCREAHGGLPATSRTLCAGILEGGKDSCQGDSGGPLICNGQFQGILSWGVHPCGQPHKPGVYTKVSDYSEWIQSIIAGNTDVTCPP", "length": 260, "molWeight": 28045, "crc64": "65A471F5C35E96F5", "md5": "08778AF99138E7FBA4F9D91CAF318B86"}}
{"primaryAccession": "P0CT92", "text": "This is Manganese lipoxygenase protein, from Rice stem rot fungus, contains 617 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CT92", "organism_name": "Rice stem rot fungus", "protein_name": "Manganese lipoxygenase", "length": 617, "firstPublicDate": "2016-05-11", "FUNCTION": "Lipoxygenase that metabolizes linoleic and alpha-linolenic acids to 9S-, 11- and 13R-hydroperoxy fatty acids, At the end of lipoxygenation, the intermediate products 11S-HPODE and 13R-HPODE from linoleic acid are then transformed into 9S-HPODE as the final product, The intermediate product 11R-HPOTrE from alpha-linolenic acid is transformed into 9S-HPOTrE and 13R-HPOTrE as the final products, 9S-HPOTrE is further oxidized by the enzyme to 9,16-DiHOTrE as the end product, Also acts on gamma-linolenic acid producing 9-HOTrE(n-6) as the main metabolite", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the lipoxygenase family, Manganese lipoxygenase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRIGLLAFAVAARYVEALPVASGEEVASSSAPTTLPSTSSSSALPSPTKYTLPHEDPNPEARKAEIALKRGGFLYGPSTLGQTTFYPSGTLGTAMSQRDQALWLRDAENQTITAYREANETLRDIQSHGGLKTLDDFALLYDGHWKASVPEGIEKGMLSNYTSDLLFSMERLSNNPYSLKRLHPTKDKLPFSVEDKVVKQLTATTLAALHKAGRLFFVDHSDQKKYTPQAGRYAAACQGLFYVDARSNQFLPLAIKTNVGADLTYTPLDDKNDWLLAKIMFNNNDLFYSQMYHVLFHTVPEIVHMAAIRTLSESHPVLAVLNRIMYQAYAIRPVGERILFNPGGFWDQNLGLPATAAVDFLSSIYAHGEGGFRAGYVENNLRKRGLVGDTFGGPALPHFPFYEDAQRVLGAIRGFMQAFVDSTYGGDDGALARDFELQDWVAEANGPAQVRDFPTAPLRRREELVGILTHIAWNTGGAHHVLNQGAPVRASGVLPLHPAALYAPVPAAKGAVASSDGLLAWLPDEVKSVEQVSLLARFNRAQVRDRNQTVRNMFAAPELLAGNGEAYAAANARFVEETGRISREIEGRGFDSKGLSQGMPFIWTALNPAVNPFFLSI", "length": 617, "molWeight": 67532, "crc64": "C9896F37DD0A9D99", "md5": "E1AE00E69E96D54FB8D1AD01FD32AF42"}}
{"primaryAccession": "P0CX31", "text": "This is Small ribosomal subunit protein eS24A protein, from Baker's yeast, contains 135 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CX31", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS24A", "length": 135, "firstPublicDate": "2011-06-28", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS24 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD", "length": 135, "molWeight": 15329, "crc64": "81B82D361207442A", "md5": "38B5E4923F38E06A0F716BD20D00593D"}}
{"primaryAccession": "P0CX32", "text": "This is Small ribosomal subunit protein eS24B protein, from Baker's yeast, contains 135 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CX32", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS24B", "length": 135, "firstPublicDate": "2011-06-28", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS24 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD", "length": 135, "molWeight": 15329, "crc64": "81B82D361207442A", "md5": "38B5E4923F38E06A0F716BD20D00593D"}}
{"primaryAccession": "P0CX82", "text": "This is Large ribosomal subunit protein eL19A protein, from Baker's yeast, contains 189 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CX82", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein eL19A", "length": 189, "firstPublicDate": "2011-06-28", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel, eL19 may play a role in the last stages of translation initiation, in particular subunit joining and shedding/releasing factors", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eL19 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA", "length": 189, "molWeight": 21704, "crc64": "776C3AB3D348EE99", "md5": "AD8E11702E13915AB74FEB295CDB8CD6"}}
{"primaryAccession": "P0CX83", "text": "This is Large ribosomal subunit protein eL19 protein, from Baker's yeast, contains 189 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CX83", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein eL19", "length": 189, "firstPublicDate": "2011-06-28", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel, eL19 may play a role in the last stages of translation initiation, in particular subunit joining and shedding/releasing factors", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eL19 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA", "length": 189, "molWeight": 21704, "crc64": "776C3AB3D348EE99", "md5": "AD8E11702E13915AB74FEB295CDB8CD6"}}
{"primaryAccession": "P0CX84", "text": "This is Large ribosomal subunit protein uL29A protein, from Baker's yeast, contains 120 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CX84", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein uL29A", "length": 120, "firstPublicDate": "2011-06-28", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the universal ribosomal protein uL29 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA", "length": 120, "molWeight": 13910, "crc64": "D8AC9DF157AD2AD6", "md5": "DA25F60EB32573246EEF7E5D6F7B1BDE"}}
{"primaryAccession": "P0CX85", "text": "This is Large ribosomal subunit protein uL29B protein, from Baker's yeast, contains 120 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CX85", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein uL29B", "length": 120, "firstPublicDate": "2011-06-28", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the universal ribosomal protein uL29 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAGVKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSLPKIKTVRKSIACVLTVINEQQREAVRQLYKGKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA", "length": 120, "molWeight": 13910, "crc64": "D8AC9DF157AD2AD6", "md5": "DA25F60EB32573246EEF7E5D6F7B1BDE"}}
{"primaryAccession": "P0DJ86", "text": "This is Thrombin-like enzyme leucurobin protein, from Whitetail lancehead, contains 231 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0DJ86", "organism_name": "Whitetail lancehead", "protein_name": "Thrombin-like enzyme leucurobin", "length": 231, "firstPublicDate": "2011-11-16", "FUNCTION": "Thrombin-like snake venom serine protease that cleaves Arg-Gly bonds in alpha-chain of fibrinogen (FGA), Induces temporary episodes of opisthotonos and rapid rolling around the long axis of the animal (gyroxin-like effect), when injected into the tail veins of mice (0,143 ug/g mouse)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Snake venom subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "VIGGDECDINEHPFLAFMYYSPRYFCGMTLINQEWVLTAAHCNRRFMRIXXXXHAGSVANYDEVVRXXXXXFICPNKKKNVITDKDIMLIRLDRPVKNSEHIAPLSLPSNPPSVGSVCRIMGWGAITTSEDTYPDVPHCANINLFNNTVCREAYNGLPAKTLCAGVLQGGIDTCGGDSGGPLICNGQFQGILSWGSDPCAEPRKPAFYTKVFDYLPWIQSIIAGNKTATCP", "length": 231, "molWeight": 25425, "crc64": "818FB388C3729A98", "md5": "504198E2BFFAA3FA99D784F098AD4F6E"}}
{"primaryAccession": "P0DJI8", "text": "This is Serum amyloid A-1 protein protein, from Human, contains 122 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0DJI8", "organism_name": "Human", "protein_name": "Serum amyloid A-1 protein", "length": 122, "firstPublicDate": "2012-07-11", "FUNCTION": "Major acute phase protein", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the SAA family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY", "length": 122, "molWeight": 13532, "crc64": "43A57D56B37CB173", "md5": "6419048503FCF083F021A552A40D3884"}}
{"primaryAccession": "P0DMC2", "text": "This is Apelin receptor early endogenous ligand protein, from Zebrafish, contains 58 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0DMC2", "organism_name": "Zebrafish", "protein_name": "Apelin receptor early endogenous ligand", "length": 58, "firstPublicDate": "2014-02-19", "FUNCTION": "Endogenous ligand for the apelin receptor (aplnra and/or aplnrb) (PubMed:24316148, PubMed:24407481), Hormone required for mesendodermal differentiation, blood vessels formation and heart morphogenesis during early development and for adult cardiovascular homeostasis (PubMed:24316148, PubMed:24407481, PubMed:26017639, PubMed:29117894), Acts as a motogen by promoting mesendodermal cell migration during gastrulation by binding and activating the apelin receptor (PubMed:24316148, PubMed:24407481, PubMed:29117894), Acts as an early embryonic regulator of cellular movement with a role in migration and development of cardiac progenitor cells (PubMed:24316148, PubMed:24407481), May act as a chemoattractant for the activation of angioblast migration toward the embryonic midline, i,e, the position of the future vessel formation, during vasculogenesis (PubMed:26017639), Positively regulates sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel sprouting, Involved in cardioprotective functions during heart failure, Mediates myocardial contractility in an ERK1/2-dependent manner (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the Elabela/Toddler family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRFFHPLYLLLLLLTVLVLISADKHGTKHDFLNLRRKYRRHNCPKKRCLPLHSRVPFP", "length": 58, "molWeight": 7021, "crc64": "BC4E7D945707AA2F", "md5": "FE045DCB6B83255F237CADF9E59A3C65"}}
{"primaryAccession": "P0DMC3", "text": "This is Apelin receptor early endogenous ligand protein, from Human, contains 54 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0DMC3", "organism_name": "Human", "protein_name": "Apelin receptor early endogenous ligand", "length": 54, "firstPublicDate": "2014-02-19", "FUNCTION": "Endogenous ligand for the apelin receptor (APLNR) (PubMed:25639753, PubMed:28137936), Hormone required for mesendodermal differentiation, blood vessels formation and heart morphogenesis during early development and for adult cardiovascular homeostasis (PubMed:25639753, PubMed:28137936), Drives internalization of APLNR, Acts as a motogen by promoting mesendodermal cell migration during gastrulation by binding and activating APLNR, Acts as an early embryonic regulator of cellular movement with a role in migration and development of cardiac progenitor cells, May act as a chemoattractant for the activation of angioblast migration toward the embryonic midline, i,e, the position of the future vessel formation, during vasculogenesis, Positively regulates sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel sprouting, Plays a role in placental vascular development; promotes placental trophoblast invasion and spiral artery remodeling in the uterus, Involved in the regulation of maternal cardiovascular homeostasis to prevent gestational hypertension and for potent cardioprotective functions during heart failure, Mediates myocardial contractility in an ERK1/2-dependent manner (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the Elabela/Toddler family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRFQQFLFAFFIFIMSLLLISGQRPVNLTMRRKLRKHNCLQRRCMPLHSRVPFP", "length": 54, "molWeight": 6622, "crc64": "6BDEB3DAFCF8BAB2", "md5": "E07AC6462F0EF105E7B9FC82AA04F297"}}
{"primaryAccession": "P10506", "text": "This is Protein kinase byr1 protein, from Fission yeast, contains 340 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P10506", "organism_name": "Fission yeast", "protein_name": "Protein kinase byr1", "length": 340, "firstPublicDate": "1989-07-01", "FUNCTION": "Serine/threonine protein kinase involved in conjugation and sporulation, It is thought that it is phosphorylated by the byr2 protein kinase and that it can phosphorylate the spk1 kinase, When bound to bob1, is involved in the regulation of sexual differentiation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFKRRRNPKGLVLNPNASVKSSDNDHKEELINNQKSFESNVEAFMEQCAHMNRRPAWISDLDNSSLEVVRHLGEGNGGAVSLVKHRNIFMARKTVYVGSDSKLQKQILRELGVLHHCRSPYIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILGKIINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGELVNSVAQTFVGTSTYMSPERIRGGKYTVKSDIWSLGISIIELATQELPWSFSNIDDSIGILDLLHCIVQEEPPRLPSSFPEDLRLFVDACLHKDPTLRASPQQLCAMPYFQQALMINVDLASWASNFRSS", "length": 340, "molWeight": 38189, "crc64": "2AC885AEE971DB8A", "md5": "1269FCB69CC11D91579E5003E5ABEEAB"}}
{"primaryAccession": "P10734", "text": "This is Zygotic gap protein knirps protein, from Fruit fly, contains 429 amino acids, has 2 NR C4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [5, 25], "description": "NR C4-type", "keyword_description": "Zinc finger", "textural_description": "NR C4-type Zinc finger"}, {"location": [42, 66], "description": "NR C4-type", "keyword_description": "Zinc finger", "textural_description": "NR C4-type Zinc finger"}], "meta_data": {"primaryAccession": "P10734", "organism_name": "Fruit fly", "protein_name": "Zygotic gap protein knirps", "length": 429, "firstPublicDate": "1989-07-01", "FUNCTION": "Transcriptional repressor, Binds to multiple sites in the eve stripe 3 enhancer element, Plays an essential role in the segmentation process both by refining the expression patterns of gap genes and by establishing pair-rules stripes of gene expression", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the nuclear hormone receptor family, NR0 subfamily", "domain_description": {"NR C4-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNQTCKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNISTISECKNEGKCIIDKKNRTTCKACRLRKCYNVGMSKGGSRYGRRSNWFKIHCLLQEHEQAAAAAGKAPPLAGGVSVGGAPSASSPVGSPHTPGFGDMAAHLHHHHQQQQQQQVPRHPHMPLLGYPSYLSDPSAALPFFSMMGGVPHQSPFQLPPHLLFPGYHASAAAAAASAADAAYRQEMYKHRQSVDSVESQNRFSPASQPPVVQPTSSARQSPIDVCLEEDVHSVHSHQSSASLLHPIAIRATPTTPTSSSPLSFAAKMQSLSPVSVCSIGGETTSVVPVHPPTVSAQEGPMDLSMKTSRSSVHSFNDSGSEDQEVEVAPRRKFYQLEAECLTTSSSSSSHSAAHSPNTTTAHAEVKRQKLGGAEATHFGGFAVAHNAASAMRGIFVCV", "length": 429, "molWeight": 45611, "crc64": "79CEE86A66AB00C7", "md5": "D904B51AF9492EEEDE590F407D44CF32"}}
{"primaryAccession": "P10911", "text": "This is Proto-oncogene DBL protein, from Human, contains 925 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P10911", "organism_name": "Human", "protein_name": "Proto-oncogene DBL", "length": 925, "firstPublicDate": "1989-07-01", "FUNCTION": "Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases, Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form, Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42, Isoform 2 exhibits decreased GEF activity toward CDC42, Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42, Isoform 4 exhibits significant activity toward RHOA and CDC42, The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the MCF2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRTFTDIGFWFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKILLTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVEVCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMALLY", "length": 925, "molWeight": 107673, "crc64": "96233C7AFC85D637", "md5": "19AAF01AA59228BDECAB429E78D278FC"}}
{"primaryAccession": "P11373", "text": "This is Cutinase 1 protein, from Anthracnose fungus, contains 224 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P11373", "organism_name": "Anthracnose fungus", "protein_name": "Cutinase 1", "length": 224, "firstPublicDate": "1989-07-01", "FUNCTION": "Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (PubMed:17043825), Degrades cutin, a macromolecule that forms the structure of the plant cuticle (PubMed:17043825), Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the cutinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFLSVLSLAITLAAAAPVEVETGVALETRQSSTRNELETGSSSACPKVIYIFARASTEPGNMGISAGPIVADALERIYGANNVWVQGVGGPYLADLASNFLPDGTSSAAINEARRLFTLANTKCPNAAIVSGGYSQGTAVMAGSISGLSTTIKNQIKGVVLFGYTKNLQNLGRIPNFETSKTEVYCDIADAVCYGTLFILPAHFLYQTDAAVAAPRFLQARIG", "length": 224, "molWeight": 23477, "crc64": "1C5BACEAB469ABFA", "md5": "AD34EA634194737F274BAF0A7250FC67"}}
{"primaryAccession": "P11456", "text": "This is Cation-dependent mannose-6-phosphate receptor protein, from Bovine, contains 279 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P11456", "organism_name": "Bovine", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "length": 279, "firstPublicDate": "1989-10-01", "FUNCTION": "Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes, Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MMSPLHSSWRTGLLLLLLFSVAVRESWQTEEKTCDLVGEKGKESEKELALLKRLTPLFNKSFESTVGQSPDMYSYVFRVCREAGNHSSGAGLVQINKSNGKETVVGRFNETQIFNGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGSILLVTLASLVAVYIIGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM", "length": 279, "molWeight": 31201, "crc64": "7351C85A32F39A70", "md5": "91C4BDF3EE576CFBEFFCA7AFFF42D685"}}
{"primaryAccession": "P11597", "text": "This is Cholesteryl ester transfer protein protein, from Human, contains 493 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P11597", "organism_name": "Human", "protein_name": "Cholesteryl ester transfer protein", "length": 493, "firstPublicDate": "1989-10-01", "FUNCTION": "Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles, Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:3600759, PubMed:24293641, PubMed:3281933), Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (PubMed:17237796)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS", "length": 493, "molWeight": 54756, "crc64": "CD7762766A9B062E", "md5": "4DB5E3EC4DC50155C7EB9D1B22796A89"}}
{"primaryAccession": "P11672", "text": "This is Neutrophil gelatinase-associated lipocalin protein, from Mouse, contains 200 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P11672", "organism_name": "Mouse", "protein_name": "Neutrophil gelatinase-associated lipocalin", "length": 200, "firstPublicDate": "1989-10-01", "FUNCTION": "Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development (PubMed:12453413), Binds iron through association with 2,3-dihydroxybenzoic acid (2,3-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context, Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration, In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration, Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis, Involved in innate immunity; limits bacterial proliferation by sequestering iron bound to microbial siderophores, such as enterobactin (PubMed:15531878, PubMed:16446425), Can also bind siderophores from M,tuberculosis (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the calycin superfamily, Lipocalin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALSVMCLGLALLGVLQSQAQDSTQNLIPAPSLLTVPLQPDFRSDQFRGRWYVVGLAGNAVQKKTEGSFTMYSTIYELQENNSYNVTSILVRDQDQGCRYWIRTFVPSSRAGQFTLGNMHRYPQVQSYNVQVATTDYNQFAMVFFRKTSENKQYFKITLYGRTKELSPELKERFTRFAKSLGLKDDNIIFSVPTDQCIDN", "length": 200, "molWeight": 22875, "crc64": "DD9A8D08750E6863", "md5": "D75541E200A91BD83226A2D7641B75EE"}}
{"primaryAccession": "P11831", "text": "This is Serum response factor protein, from Human, contains 508 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P11831", "organism_name": "Human", "protein_name": "Serum response factor", "length": 508, "firstPublicDate": "1989-10-01", "FUNCTION": "SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS), Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration, The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics, Required for cardiac differentiation and maturation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLPTQAGAAAALGRGSALGGSLNRTPTGRPGGGGGTRGANGGRVPGNGAGLGPGRLEREAAAAAATTPAPTAGALYSGSEGDSESGEEEELGAERRGLKRSLSEMEIGMVVGGPEASAAATGGYGPVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDPTTDQRMSATGFEETDLTYQVSESDSSGETKDTLKPAFTVTNLPGTTSTIQTAPSTSTTMQVSSGPSFPITNYLAPVSASVSPSAVSSANGTVLKSTGSGPVSSGGLMQLPTSFTLMPGGAVAQQVPVQAIQVHQAPQQASPSRDSSTDLTQTSSSGTVTLPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLGDGSLTVLNAFSQAPSTMQVSHSQVQEPGGVPQVFLTASSGTVQIPVSAVQLHQMAVIGQQAGSSSNLTELQVVNLDTAHSTKSE", "length": 508, "molWeight": 51593, "crc64": "25505828D3276F44", "md5": "09AC0D488C098F80EB6395952253B430"}}
{"primaryAccession": "P11911", "text": "This is B-cell antigen receptor complex-associated protein alpha chain protein, from Mouse, contains 220 amino acids, has 1 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [29, 117], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "P11911", "organism_name": "Mouse", "protein_name": "B-cell antigen receptor complex-associated protein alpha chain", "length": 220, "firstPublicDate": "1989-10-01", "FUNCTION": "Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation, Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells, Stimulates SYK autophosphorylation and activation, Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK, Also interacts with and increases activity of some Src-family tyrosine kinases, Represses BCR signaling during development of immature B-cells", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {"Ig-like C2-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPGGLEALRALPLLLFLSYACLGPGCQALRVEGGPPSLTVNLGEEARLTCENNGRNPNITWWFSLQSNITWPPVPLGPGQGTTGQLFFPEVNKNHRGLYWCQVIENNILKRSCGTYLRVRNPVPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKFGVDMPDDYEDENLYEGLNLDDCSMYEDISRGLQGTYQDVGNLHIGDAQLEKP", "length": 220, "molWeight": 24583, "crc64": "A4C648C2BE6D3E38", "md5": "621418FC408610387385A457F61A344E"}}
{"primaryAccession": "P12843", "text": "This is Insulin-like growth factor-binding protein 2 protein, from Rat, contains 304 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P12843", "organism_name": "Rat", "protein_name": "Insulin-like growth factor-binding protein 2", "length": 304, "firstPublicDate": "1989-10-01", "FUNCTION": "Inhibits IGF-mediated growth and developmental rates (By similarity), IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture, They alter the interaction of IGFs with their cell surface receptors", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLPRLGGPALPLLLPSLLLLLLLGAGGCGPGVRAEVLFRCPPCTPERLAACGPPPDAPCAELVREPGCGCCSVCARQEGEACGVYIPRCAQTLRCYPNPGSELPLKALVTGAGTCEKRRVGATPQQVADSEDDHSEGGLVENHVDGTMNMLGGSSAGRKPPKSGMKELAVFREKVNEQHRQMGKGAKHLSLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDDRGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKPIQGAPTIRGDPECHLFYNEQQENDGAHAQRVQ", "length": 304, "molWeight": 32855, "crc64": "8558B7E2C9152B9F", "md5": "316DB53393858CBB748941F954A995D2"}}
{"primaryAccession": "P12979", "text": "This is Myogenin protein, from Mouse, contains 224 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P12979", "organism_name": "Mouse", "protein_name": "Myogenin", "length": 224, "firstPublicDate": "1990-01-01", "FUNCTION": "Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy, Essential for the development of functional embryonic skeletal fiber muscle differentiation, However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity, Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation, During terminal myoblast differentiation, plays a role as a strong activator of transcription at loci with an open chromatin structure previously initiated by MYOD1, Together with MYF5 and MYOD1, co-occupies muscle-specific gene promoter core regions during myogenesis, Cooperates also with myocyte-specific enhancer factor MEF2D and BRG1-dependent recruitment of SWI/SNF chromatin-remodeling enzymes to alter chromatin structure at myogenic late gene promoters, Facilitates cell cycle exit during terminal muscle differentiation through the up-regulation of miR-20a expression, which in turn represses genes involved in cell cycle progression, Binds to the E-box containing (E1) promoter region of the miR-20a gene, Plays also a role in preventing reversal of muscle cell differentiation, Contributes to the atrophy-related gene expression in adult denervated muscles, Induces fibroblasts to differentiate into myoblasts", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MELYETSPYFYQEPHFYDGENYLPVHLQGFEPPGYERTELSLSPEARGPLEEKGLGTPEHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPMVPSECNSHSASCSPEWGNALEFGPNPGDHLLAADPTDAHNLHSLTSIVDSITVEDMSVAFPDETMPN", "length": 224, "molWeight": 25203, "crc64": "CC7352C1EDF9D3D8", "md5": "A49F83C37C12EF40B121448E9F640454"}}
{"primaryAccession": "P13010", "text": "This is X-ray repair cross-complementing protein 5 protein, from Human, contains 732 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P13010", "organism_name": "Human", "protein_name": "X-ray repair cross-complementing protein 5", "length": 732, "firstPublicDate": "1990-01-01", "FUNCTION": "Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA (PubMed:7957065, PubMed:8621488, PubMed:12145306, PubMed:11493912), Required for double-strand break repair and V(D)J recombination (PubMed:7957065, PubMed:8621488, PubMed:12145306, PubMed:11493912), Also has a role in chromosome translocation (PubMed:7957065, PubMed:8621488, PubMed:12145306, PubMed:11493912), The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner (PubMed:7957065, PubMed:8621488, PubMed:12145306, PubMed:11493912), It works in the 3'-5' direction (PubMed:7957065, PubMed:8621488, PubMed:12145306, PubMed:11493912), During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and binds to the broken ends of the DNA and protects them from further resection (PubMed:7957065, PubMed:8621488, PubMed:12145306, PubMed:11493912), Binding to DNA may be mediated by XRCC6 (PubMed:7957065, PubMed:8621488, PubMed:12145306, PubMed:11493912), The XRCC5-XRRC6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold (PubMed:7957065, PubMed:8621488, PubMed:12145306, PubMed:20383123, PubMed:11493912), The XRCC5-XRRC6 dimer is probably involved in stabilizing broken DNA ends and bringing them together (PubMed:7957065, PubMed:8621488, PubMed:12145306, PubMed:20383123), The assembly of the DNA-PK complex to DNA ends is required for the NHEJ ligation step (PubMed:7957065, PubMed:8621488, PubMed:12145306, PubMed:20383123), The XRCC5-XRRC6 dimer probably also acts as a 5'-deoxyribose-5-phosphate lyase (5'-dRP lyase), by catalyzing the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site near double-strand breaks (PubMed:20383123), XRCC5 probably acts as the catalytic subunit of 5'-dRP activity, and allows to 'clean' the termini of abasic sites, a class of nucleotide damage commonly associated with strand breaks, before such broken ends can be joined (PubMed:20383123), The XRCC5-XRRC6 dimer together with APEX1 acts as a negative regulator of transcription (PubMed:8621488), In association with NAA15, the XRCC5-XRRC6 dimer binds to the osteocalcin promoter and activates osteocalcin expression (PubMed:12145306), As part of the DNA-PK complex, involved in the early steps of ribosome assembly by promoting the processing of precursor rRNA into mature 18S rRNA in the small-subunit processome (PubMed:32103174), Binding to U3 small nucleolar RNA, recruits PRKDC and XRCC5/Ku86 to the small-subunit processome (PubMed:32103174), Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ku80 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFGTDGTDNPLSGGDQYQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQHETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGDGPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKIERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDDDETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQVLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLVYVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTTKIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLIEAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRVLVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFEEGGDVDDLLDMI", "length": 732, "molWeight": 82705, "crc64": "2363CA84834E74A3", "md5": "80ABC9CD1D17278C7193551BD701A75E"}}
{"primaryAccession": "P13432", "text": "This is SMR1 protein protein, from Rat, contains 146 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P13432", "organism_name": "Rat", "protein_name": "SMR1 protein", "length": 146, "firstPublicDate": "1990-01-01", "FUNCTION": "Sialorphin is an endogenous inhibitor of neprilysin, Inhibits the breakdown of Met-enkephalin and substance P in isolated tissue from the dorsal zone of the rat spinal cord, Has an analgesic effect when administered to rats by intravenous injection", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKSLYLIFGLWILLACFQSGEGVRGPRRQHNPRRQQDPSTLPHYLGLQPDPNGGQIGVTITIPLNLQPPRVLVNLPGFITGPPLVVQGTTEYQYQWQLTAPDPTPLSNPPTQLHSTEQANTKTDAKISNTTATTQNSTDIFEGGGK", "length": 146, "molWeight": 15970, "crc64": "F31B619A3BD85B5C", "md5": "C202289733C52CDE19BEE75DFD2E604C"}}
{"primaryAccession": "P13528", "text": "This is Transcription factor unc-86 protein, from Caenorhabditis elegans, contains 357 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P13528", "organism_name": "Caenorhabditis elegans", "protein_name": "Transcription factor unc-86", "length": 357, "firstPublicDate": "1990-01-01", "FUNCTION": "Transcription factor required for correct cell fate determination and differentiation in diverse neuronal cell lineages where it plays a role in specifying the fate of daughter cells during cell divisions (PubMed:7237544, PubMed:2257628, PubMed:26096732, PubMed:10899123), Involved in sensory neuron production and function (PubMed:1361171, PubMed:9735371, PubMed:10899123, PubMed:26096732), Binds both alone and with mec-3 to the mec-3 promoter to initiate and maintain mec-3 expression which is required for sensory neuron differentiation (PubMed:1361171, PubMed:9735371), In addition, binds both alone and with mec-3 to the promoters of mec-4 and mec-7 which act to regulate sensory neuron function (PubMed:9735371, PubMed:10899123), Involved in determining the identity of the serotonergic NSM neurons and the cholinergic IL2 sensory and URA motor neurons (PubMed:24353061), Promotes expression of the cfi-1 transcription factor in the URA and IL2 neurons which in turn activates normal URA and IL2 gene expression (PubMed:24353061, PubMed:11959845), Required to determine the identity of BDU sensory neurons in concert with transcription factor unc-86, regulating expression of a number of genes, including transcription factors ceh-14 and ahr-1, neuropeptides flp-10, nlp-1 and nlp-15, and tyramine receptor-encoding ser-2 (PubMed:26096732), Regulates expression of a number of genes in NSM neurons including bas-1, cat-1, dop-3, mgl-3, nlp-13, scd-2 and ptps-1 (PubMed:24353061), In the IL2 neurons, required for expression of cho-1, gcy-19, klp-6, lag-2, unc-5 and unc-17 (PubMed:24353061), Promotes expression of pkd-2 in the male-specific CEM head neurons (PubMed:11959845), Required for dauer-specific branching of IL2Q neurons and nictation behavior (PubMed:23932402), Controls both the timing and direction of axon outgrowth in HSN neurons (PubMed:21656875), Plays a role in serotonin production by regulating expression of the tryptophan hydrolase tph-1 which catalyzes serotonin synthesis, in the AIM, NSM, HSN and RIH neurons (PubMed:12135927), Involved in regulation of lin-11 expression in the AIZ interneurons, the major interneurons of the olfactory pathway, and is required for odortaxis behavior (PubMed:12883006), Involved in neurite pruning between AIM neurons during larval development by regulating the expression of transcription factor mbr-1 (PubMed:16139210), Required for correct localization of unc-40 (PubMed:24353061)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the POU transcription factor family, Class-4 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQNTAPVPTTTTASKMQPFNNSLFGSFDDPILNARAAQVALADIDVKNVPQLTNPLMRPHDMFSYSNYFSGIHDTSAATNIYQGLPSSSEPFDASVVVPTSSDDQMTPLQQVMAMQQSYGAPPPFQYNMTHPFSTTSIASSNNLARYPIAPPTSDMDTDPRQLETFAEHFKQRRIKLGVTQADVGKALAHLKMPGVGSLSQSTICRFESLTLSHNNMVALKPILHSWLEKAEEAMKQKDTIGDINGILPNTDKKRKRTSIAAPEKRELEQFFKQQPRPSGERIASIADRLDLKKNVVRVWFCNQRQKQKRDFRSQFRARSAAAVMGPRVMPVLNGNNSNNNLKQGQTTYNGLPGFFD", "length": 357, "molWeight": 39737, "crc64": "1B9830CA8E04ADAC", "md5": "E0CABFDE37F50E89B6EAADC7E6439829"}}
{"primaryAccession": "P14020", "text": "This is Dolichol-phosphate mannosyltransferase protein, from Baker's yeast, contains 267 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P14020", "organism_name": "Baker's yeast", "protein_name": "Dolichol-phosphate mannosyltransferase", "length": 267, "firstPublicDate": "1990-01-01", "FUNCTION": "Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyltransferase 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSIEYSVIVPAYHEKLNIKPLTTRLFAGMSPEMAKKTELIFVDDNSQDGSVEEVDALAHQGYNVRIIVRTNERGLSSAVLKGFYEAKGQYLVCMDADLQHPPETVPKLFESLHDHAFTLGTRYAPGVGIDKDWPMYRRVISSTARMMARPLTIASDPMSGFFGLQKKYLENCNPRDINSQGFKIALELLAKLPLPRDPRVAIGEVPFTFGVRTEGESKLSGKVIIQYLQQLKELYVFKFGANNLILFITFWSILFFYVCYQLYHLVF", "length": 267, "molWeight": 30362, "crc64": "14F2F59F7B6A391A", "md5": "1FF903D8DFDCCD906278A19E58E3E3A6"}}
{"primaryAccession": "P14448", "text": "This is Fibrinogen alpha chain protein, from Chicken, contains 741 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P14448", "organism_name": "Chicken", "protein_name": "Fibrinogen alpha chain", "length": 741, "firstPublicDate": "1990-01-01", "FUNCTION": "Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix, Fibrin has a major function in hemostasis as one of the primary components of blood clots", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIPVTILCVLLCLNLAWAQDGKTTFEKEGGGGRGPRILENMHESSCKYEKNWPICVDDDWGTKCPSCCRMQGIIDDTDQNYSQRIDNIRQQLADSQNKYKTSNRVIVETINILKPGLEGAQQLDENYGHVSTELRRRIVTLKQRVATQVNRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCARSFDYQVDKEGYDNIQKHLTQASSIDMHPDFQTTTLSTLKMRPLKDSNVPEHFKLKPSPEMQAMSAFNNIKQMQVVLERPETDHVAEARGDSSPSHTGKLITSSHRRESPSLVDKTSSASSVHRCTRTVTKKVISGPDGPREEIVEKMVSSDGSDCSHLQGGREGSTYHFSGTGDFHKLDRLLPDLESFFTHDSVSTSSRHSIGSSTSSHVTGAGSSHLGTGGKDKFTDLGEEEEDDFGGLQPSGFAAGSASHSKTVLTSSSSSFNKGGSTFETKSLKTRETSEQLGGVQHDQSAEDTPDFKARSFRPAAMSTRRSYNGKDCDDIRQKHTSGAKSGIFKIKPEGSNKVLSVYCDQETTLGGWLLIQQRMDGSVNFNRTWQDYRRGFGSVDGKGQGELWLGNENIHLLTQNDTLLRVELEDWDGNAAYAEYIVQVGTEAEGYALTVSSYEGTAGDALVAGWLEEGSEYTSHAQMQFSTFDRDQDHWEESCAEVYGGGWWYNSCQAANLNGIYYPGGHYDPRYNVPYEIENGVVWIPFRASDYSLKVVRMKIRPLETL", "length": 741, "molWeight": 82438, "crc64": "A09F5F4F186DE3A6", "md5": "59AC637AA2471A16F90B658A418D9AEF"}}
{"primaryAccession": "P14724", "text": "This is Anaphase-promoting complex subunit CDC26 protein, from Baker's yeast, contains 124 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P14724", "organism_name": "Baker's yeast", "protein_name": "Anaphase-promoting complex subunit CDC26", "length": 124, "firstPublicDate": "1990-04-01", "FUNCTION": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle, The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome, In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition, In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CDC26 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIRRAPTTLQLSHDDVTSLIDDLNEQKLKQQLNIEKTKYFQGKNGGSLHSNTDFQDTSQNIEDNNNDNDNDIDEDDDMSSYNDKAASVAHTRVLNSLHLSTDSNTAHETSNANDNHNPFYIREE", "length": 124, "molWeight": 14081, "crc64": "F41EECD2B56C4FB5", "md5": "CD2BF2A8249EB1F3EBC7457586E8EDB0"}}
{"primaryAccession": "P15382", "text": "This is Potassium voltage-gated channel subfamily E member 1 protein, from Human, contains 129 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P15382", "organism_name": "Human", "protein_name": "Potassium voltage-gated channel subfamily E member 1", "length": 129, "firstPublicDate": "1990-04-01", "FUNCTION": "Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits, Modulates the gating kinetics and enhances stability of the channel complex, Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:19219384), Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel, The outward current reaches its steady state only after 50 seconds, Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the potassium channel KCNE family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP", "length": 129, "molWeight": 14675, "crc64": "5442D70929D4E87E", "md5": "0011AB0C11C7FEA51FEFCD039B1B69F5"}}
{"primaryAccession": "P15383", "text": "This is Potassium voltage-gated channel subfamily E member 1 protein, from Rat, contains 130 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P15383", "organism_name": "Rat", "protein_name": "Potassium voltage-gated channel subfamily E member 1", "length": 130, "firstPublicDate": "1990-04-01", "FUNCTION": "Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits, Modulates the gating kinetics and enhances stability of the channel complex, Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:19219384), Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel, The outward current reaches its steady state only after 50 seconds, Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the potassium channel KCNE family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MALSNSTTVLPFLASLWQETDEPGGNMSADLARRSQLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNVYIESDAWQEKGKALFQARVLESFRACYVIENQAAVEQPATHLPELKPLS", "length": 130, "molWeight": 14699, "crc64": "76717E7ED73C5E4D", "md5": "AF8DEB200348A4E276400FE587FBD9BF"}}
{"primaryAccession": "P15424", "text": "This is ATP-dependent RNA helicase MSS116, mitochondrial protein, from Baker's yeast, contains 664 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P15424", "organism_name": "Baker's yeast", "protein_name": "ATP-dependent RNA helicase MSS116, mitochondrial", "length": 664, "firstPublicDate": "1990-04-01", "FUNCTION": "ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns, Specifically involved in the ATP-dependent splicing of the bl1 intron of COB, Also required for efficient mitochondrial translation", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the DEAD box helicase family, DDX18/HAS1 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLTSILIKGRTPVLASRNLLAALSNCNHITWAVSRRLYNDGNRDQRNFGRNQRNNNSNRYRNSRFNSRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEPEDISDIVISLISSYRSCIKEYRFSERRILPEIASTYGVLLNDPQLKIPVSRRFLDKLGLSRSPIGKAMFEIRDYSSRDGNNKSYDYDDDSEISFRGNKNYNNRSQNRDYDDEPFRRSNNNRRSFSRSNDKNNYSSRNSNIY", "length": 664, "molWeight": 76269, "crc64": "DAEECCA4ED0CB2BE", "md5": "6A10E3C2B355728573F36202E23A2982"}}
{"primaryAccession": "P15693", "text": "This is Intestinal-type alkaline phosphatase 1 protein, from Rat, contains 540 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P15693", "organism_name": "Rat", "protein_name": "Intestinal-type alkaline phosphatase 1", "length": 540, "firstPublicDate": "1990-04-01", "FUNCTION": "Alkaline phosphatase that can hydrolyze various phosphate compounds", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the alkaline phosphatase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS", "length": 540, "molWeight": 58402, "crc64": "29AC2B543CBE6B52", "md5": "06338D821B9B24C1011FC881C5F8B26A"}}
{"primaryAccession": "P15705", "text": "This is Heat shock protein STI1 protein, from Baker's yeast, contains 589 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P15705", "organism_name": "Baker's yeast", "protein_name": "Heat shock protein STI1", "length": 589, "firstPublicDate": "1990-04-01", "FUNCTION": "May play a role in mediating the heat shock response of some HSP70 genes, It is required for optimal growth of yeast cells at both low and high temperature", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSLTADEYKQQGNAAFTAKDYDKAIELFTKAIEVSETPNHVLYSNRSACYTSLKKFSDALNDANECVKINPSWSKGYNRLGAAHLGLGDLDEAESNYKKALELDASNKAAKEGLDQVHRTQQARQAQPDLGLTQLFADPNLIENLKKNPKTSEMMKDPQLVAKLIGYKQNPQAIGQDLFTDPRLMTIMATLMGVDLNMDDINQSNSMPKEPETSKSTEQKKDAEPQSDSTTSKENSSKAPQKEESKESEPMEVDEDDSKIEADKEKAEGNKFYKARQFDEAIEHYNKAWELHKDITYLNNRAAAEYEKGEYETAISTLNDAVEQGREMRADYKVISKSFARIGNAYHKLGDLKKTIEYYQKSLTEHRTADILTKLRNAEKELKKAEAEAYVNPEKAEEARLEGKEYFTKSDWPNAVKAYTEMIKRAPEDARGYSNRAAALAKLMSFPEAIADCNKAIEKDPNFVRAYIRKATAQIAVKEYASALETLDAARTKDAEVNNGSSAREIDQLYYKASQQRFQPGTSNETPEETYQRAMKDPEVAAIMQDPVMQSILQQAQQNPAALQEHMKNPEVFKKIQTLIAAGIIRTGR", "length": 589, "molWeight": 66265, "crc64": "CF8A85C2BBD3C44C", "md5": "8FDB6F7406E9C2F699BB305B286F285B"}}
{"primaryAccession": "P15891", "text": "This is Actin-binding protein protein, from Baker's yeast, contains 592 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P15891", "organism_name": "Baker's yeast", "protein_name": "Actin-binding protein", "length": 592, "firstPublicDate": "1990-04-01", "FUNCTION": "Regulates ARP2/3 complex-mediated actin assembly, Recruits ARP2/3 complex to sides of preexisting actin filaments, which may promote nucleation or stabilization of filament branches, Binds to actin filaments, but not actin monomers, Actin binding is required for ARP2/3 complex activation, May also have a role in linking the actin cytoskeleton to endocytosis, recruits components of the endocytotic machinery to cortical actin patches, known sites of endocytosis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ABP1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALEPIDYTTHSREIDAEYLKIVRGSDPDTTWLIISPNAKKEYEPESTGSSFHDFLQLFDETKVQYGLARVSPPGSDVEKIIIIGWCPDSAPLKTRASFAANFAAVANNLFKGYHVQVTARDEDDLDENELLMKISNAAGARYSIQTSSKQQGKASTPPVKKSFTPSKSPAPVSKKEPVKTPSPAPAAKISSRVNDNNDDDDWNEPELKERDFDQAPLKPNQSSYKPIGKIDLQKVIAEEKAKEDPRLVQKPTAAGSKIDPSSDIANLKNESKLKRDSEFNSFLGTTKPPSMTESSLKNDDDKVIKGFRNEKSPAQLWAERKAKQNSGNAETKAEAPKPEVPEDEPEGEPDVKDLKSKFEGLAASEKEEEEMENKFAPPPKKSEPTIISPKPFSKPQEPVKAEEAEQPKTDYKKIGNPLPGMHIEADNEEEPEENDDDWDDDEDEAAQPPLPSRNVASGAPVQKEEPEQEEIAPSLPSRNSIPAPKQEEAPEQAPEEEIEEEAEEAAPQLPSRSSAAPPPPPRRATPEKKPKENPWATAEYDYDAAEDNELTFVENDKIINIEFVDDDWWLGELEKDGSKGLFPSNYVSLGN", "length": 592, "molWeight": 65576, "crc64": "39523510704D94AA", "md5": "3DEF9B50F15F21285B58C3688089A117"}}
{"primaryAccession": "P16068", "text": "This is Guanylate cyclase soluble subunit beta-1 protein, from Bovine, contains 619 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P16068", "organism_name": "Bovine", "protein_name": "Guanylate cyclase soluble subunit beta-1", "length": 619, "firstPublicDate": "1990-04-01", "FUNCTION": "Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the adenylyl cyclase class-4/guanylyl cyclase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDADKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETEQDEN", "length": 619, "molWeight": 70502, "crc64": "8EFB14952B80F344", "md5": "803870344EBF4C04531C0E5A5DCE9969"}}
{"primaryAccession": "P16104", "text": "This is Histone H2AX protein, from Human, contains 143 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P16104", "organism_name": "Human", "protein_name": "Histone H2AX", "length": 143, "firstPublicDate": "1990-04-01", "FUNCTION": "Variant histone H2A which replaces conventional H2A in a subset of nucleosomes, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQEY", "length": 143, "molWeight": 15145, "crc64": "D4683775C2E6C3A9", "md5": "1081F21A7ADBEFB8176ABA362661E6DC"}}
{"primaryAccession": "P16410", "text": "This is Cytotoxic T-lymphocyte protein 4 protein, from Human, contains 223 amino acids, has 1 Ig-like V-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [39, 140], "description": "Ig-like V-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like V-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "P16410", "organism_name": "Human", "protein_name": "Cytotoxic T-lymphocyte protein 4", "length": 223, "firstPublicDate": "1990-08-01", "FUNCTION": "Inhibitory receptor acting as a major negative regulator of T-cell responses, The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {"Ig-like V-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN", "length": 223, "molWeight": 24656, "crc64": "6F9466FB2E139A5A", "md5": "16EDF55FD204A38F8D026EC118FA1560"}}
{"primaryAccession": "P17427", "text": "This is AP-2 complex subunit alpha-2 protein, from Mouse, contains 938 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P17427", "organism_name": "Mouse", "protein_name": "AP-2 complex subunit alpha-2", "length": 938, "firstPublicDate": "1990-08-01", "FUNCTION": "Component of the adaptor protein complex 2 (AP-2), Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways, Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation, AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome, The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components, Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation, AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis, AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface, AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules, AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway, During long-term potentiation in hippocampal neurons, AP-2 is responsible for the endocytosis of ADAM10 (PubMed:23676497), The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane, The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins, The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the adaptor complexes large subunit family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKATIQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPERESSILAKLKKKKGPSTVTDLEETKRERSIDVNGGPEPVPASTSAASTPSPSADLLGLGAVPPAPTGPPPSSGGGLLVDVFSDSASAVAPLAPGSEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICADDLQTNLNLQTKPVDPTVDGGAQVQQVVNIECISDFTEAPVLNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEVQNIFKAKHPMDTEITKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGCLLRLEPNLQAQMYRLTLRTSKDTVSQRLCELLSEQF", "length": 938, "molWeight": 104017, "crc64": "183FE8DFE199DBCA", "md5": "9755674ADD06A73895DDEA2A511D4D36"}}
{"primaryAccession": "P17568", "text": "This is NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 protein, from Human, contains 137 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P17568", "organism_name": "Human", "protein_name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7", "length": 137, "firstPublicDate": "1990-08-01", "FUNCTION": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis, Complex I functions in the transfer of electrons from NADH to the respiratory chain, The immediate electron acceptor for the enzyme is believed to be ubiquinone", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the complex I NDUFB7 subunit family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGAHLVRRYLGDASVEPDPLQMPTFPPDYGFPERKEREMVATQQEMMDAQLRLQLRDYCAHHLIRLLKCKRDSFPNFLACKQERHDWDYCEHRDYVMRMKEFERERRLLQRKKRREKKAAELAKGQGPGEVDPKVAL", "length": 137, "molWeight": 16402, "crc64": "2743716544288776", "md5": "521A0ED9450F26C28EAC953020C5CF33"}}
{"primaryAccession": "P17629", "text": "This is THO complex subunit HPR1 protein, from Baker's yeast, contains 752 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P17629", "organism_name": "Baker's yeast", "protein_name": "THO complex subunit HPR1", "length": 752, "firstPublicDate": "1990-08-01", "FUNCTION": "Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export, The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription, THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase, It functions in cotranscriptional formation of an export-competent messenger ribonucleoprotein particle (mRNP) by facilitating the loading of ATP-dependent RNA helicase SUB2 and the mRNA export factor YRA1 along the nascent mRNA", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSNTEELIQNSIGFLQKTFKALPVSFDSIRHEPLPSSMLHASVLNFEWEPLEKNISAIHDRDSLIDIILKRFIIDSMTNAIEDEEENNLEKGLLNSCIGLDFVYNSRFNRSNPASWGNTFFELFSTIIDLLNSPSTFLKFWPYAESRIEWFKMNTSVEPVSLGESNLISYKQPLYEKLRHWNDILAKLENNDILNTVKHYNMKYKLENFLSELLPINEESNFNRSASISALQESDNEWNRSARERESNRSSDVIFAADYNFVFYHLIICPIEFAFSDLEYKNDVDRSLSPLLDAILEIEENFYSKIKMNNRTRYSLEEALNTEYYANYDVMTPKLPVYMKHSNAMKMDRNEFWANLQNIKESDDYTLRPTIMDISLSNTTCLYKQLTQEDDDYYRKQFILQLCFTTNLIRNLISSDETRNFYKSCYLRENPLSDIDFENLDEVNKKRGLNLCSYICDNRVLKFYKIKDPDFYRVIRKLMSSDEKFTTAKIDGFKEFQNFRISKEKIPPPAFDETFKKFTFIKMGNKLINNVWKIPTGLDKIEQEVKKPEGVYEAAQAKWESKISSETSGGEAKDEIIRQWQTLRFLRSRYLFDFDKVNEKTGVDGLFEEPRKVEALDDSFKEKLLYKINQEHRKKLQDAREYKIGKERKKRALEEEASFPEREQKIKSQRINSASQTEGDELKSEQTQPKGEISEENTKIKSSEVSSQDPDSGVAGEFAPQNTTAQLENPKTEDNNAATSNISNGSSTQDMK", "length": 752, "molWeight": 87829, "crc64": "CBD92432F099AD22", "md5": "B9EAD712B29AC9308A75C3DA7F9265C6"}}
{"primaryAccession": "P17936", "text": "This is Insulin-like growth factor-binding protein 3 protein, from Human, contains 291 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P17936", "organism_name": "Human", "protein_name": "Insulin-like growth factor-binding protein 3", "length": 291, "firstPublicDate": "1990-11-01", "FUNCTION": "IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture, They alter the interaction of IGFs with their cell surface receptors, Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R, Inhibits the positive effect of humanin on insulin sensitivity (PubMed:19623253), Promotes testicular germ cell apoptosis (PubMed:19952275)", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK", "length": 291, "molWeight": 31674, "crc64": "A9682065AB266586", "md5": "C06E8291F9934446B3F82E18679083B5"}}
{"primaryAccession": "P18911", "text": "This is Retinoic acid receptor gamma protein, from Mouse, contains 458 amino acids, has 2 NR C4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [90, 110], "description": "NR C4-type", "keyword_description": "Zinc finger", "textural_description": "NR C4-type Zinc finger"}, {"location": [126, 150], "description": "NR C4-type", "keyword_description": "Zinc finger", "textural_description": "NR C4-type Zinc finger"}], "meta_data": {"primaryAccession": "P18911", "organism_name": "Mouse", "protein_name": "Retinoic acid receptor gamma", "length": 458, "firstPublicDate": "1990-11-01", "FUNCTION": "Receptor for retinoic acid, Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes, The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5, In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (By similarity), Required for limb bud development, In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the nuclear hormone receptor family, NR1 subfamily", "domain_description": {"NR C4-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATNKERLFAPGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSKPGPHPKASSEDEAPGGQGKRGQSPQPDQGP", "length": 458, "molWeight": 50891, "crc64": "1D13D2F1482D7194", "md5": "DE58225B9A9670629B7A23EAC33D51C0"}}
{"primaryAccession": "P18965", "text": "This is Factor V activator RVV-V gamma protein, from Eastern Russel's viper, contains 260 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P18965", "organism_name": "Eastern Russel's viper", "protein_name": "Factor V activator RVV-V gamma", "length": 260, "firstPublicDate": "1990-11-01", "FUNCTION": "Venom serine protease that selectively activates factor V (F5) in a calcium-independent manner, It cleaves the Arg(1545)-Ser(1546) linkage in the human factor V molecule, Induces the coagulation of mammalian plasma", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Snake venom subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVLIKVLANLLVLQLSYAQKSSELVVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGVGSRCRIMGWGKISTTEDTYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGRDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGNRTVTCPP", "length": 260, "molWeight": 28823, "crc64": "CDFC23F40C0EC8F1", "md5": "F2030D77E6550A37AC8337E4897E1143"}}
{"primaryAccession": "P19136", "text": "This is Manganese peroxidase H4 protein, from White-rot fungus, contains 382 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P19136", "organism_name": "White-rot fungus", "protein_name": "Manganese peroxidase H4", "length": 382, "firstPublicDate": "1990-11-01", "FUNCTION": "Catalyzes the oxidation of Mn(2+) to Mn(3+), The latter, acting as a diffusible redox mediator, is capable of oxidizing a variety of lignin compounds", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peroxidase family, Ligninase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFGSLLAFVALAAITRAAPTAESAVCPDGTRVTNAACCAFIPLAQDLQETLFQGDCGEDAHEVIRLTFHDAIAISQSLGPQAGGGADGSMLHFPTIEPNFSANSGIDDSVNNLLPFMQKHDTISAADLVQFAGAVALSNCPGAPRLEFMAGRPNTTIPAVEGLIPEPQDSVTKILQRFEDAGNFSPFEVVSLLASHTVARADKVDETIDAAPFDSTPFTFDTQVFLEVLLKGTGFPGSNNNTGEVMSPLPLGSGSDTGEMRLQSDFALARDERTACFWQSFVNEQEFMAASFKAAMAKLAILGHSRSSLIDCSDVVPVPKPAVNKPATFPATKGPKDLDTLTCKALKFPTLTSDPGATETLIPHCSNGGMSCPGVQFDGPA", "length": 382, "molWeight": 40115, "crc64": "75E2A6B762867E3D", "md5": "FB16963E30B13BC73F978975328AFA81"}}
{"primaryAccession": "P19236", "text": "This is Mastin protein, from Dog, contains 280 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P19236", "organism_name": "Dog", "protein_name": "Mastin", "length": 280, "firstPublicDate": "1990-11-01", "FUNCTION": "Trypsin-like serine protease, Has a preference for extended substrates with basic residues at the P1 position; Arg is preferred over Lys, Active towards calcitonin gene-related peptide and gelatin, Not active towards substance P, vasoactive intestinal peptide, type I collagen or azocasein", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLWLLVLTAPWLGGSVPISPDPGLRHEQVGIVGGCKVPARRYPWQVSLRFHGMGSGQWQHICGGSLIHPQWVLTAAHCVELEGLEAATLRVQVGQLRLYDHDQLCNVTEIIRHPNFNMSWYGWDSADIALLKLEAPLTLSEDVNLVSLPSPSLIVPPGMLCWVTGWGDIADHTPLPPPYHLQEVEVPIVGNRECNCHYQTILEQDDEVIKQDMLCAGSEGHDSCQMDSGGPLVCRWKCTWIQVGVVSWGYGCGYNLPGVYARVTSYVSWIHQHIPLSPGP", "length": 280, "molWeight": 31025, "crc64": "20D2A44A02B8D986", "md5": "B0E64A0764C47EEBB2E51F75225EFE47"}}
{"primaryAccession": "P19427", "text": "This is Dermatopontin protein, from Bovine, contains 201 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P19427", "organism_name": "Bovine", "protein_name": "Dermatopontin", "length": 201, "firstPublicDate": "1991-02-01", "FUNCTION": "Seems to mediate adhesion by cell surface integrin binding, May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment, Enhances TGFB1 activity, Inhibits cell proliferation, Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the dermatopontin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDLTLLWVLLPLVTVAWGQYGDYGYSYHQYHDYSDDGWVNLNRQGFSYQCPHGQVVVAVRSIFNKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFANV", "length": 201, "molWeight": 24012, "crc64": "6AE0F65756AABC7F", "md5": "23C310DFD67AB713C751E28BDCD5D651"}}
{"primaryAccession": "P19492", "text": "This is Glutamate receptor 3 protein, from Rat, contains 888 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P19492", "organism_name": "Rat", "protein_name": "Glutamate receptor 3", "length": 888, "firstPublicDate": "1991-02-01", "FUNCTION": "Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission, L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system, Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse, The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist, In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glutamate-gated ion channel (TC 1,A,10,1) family, GRIA3 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI", "length": 888, "molWeight": 100373, "crc64": "2981616375661703", "md5": "D0A9DADFF36F870EF0667860C08C269E"}}
{"primaryAccession": "P20385", "text": "This is Chorion transcription factor Cf2 protein, from Fruit fly, contains 510 amino acids, has 7 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [74, 97], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [125, 148], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [366, 388], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [401, 423], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [429, 451], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [457, 479], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [485, 508], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "P20385", "organism_name": "Fruit fly", "protein_name": "Chorion transcription factor Cf2", "length": 510, "firstPublicDate": "1991-02-01", "FUNCTION": "Transcriptional regulator; binds to the promoter region of Cp15, Also binds to its own promoter, thus having a probable autoregulatory role", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 7}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIKSTTNPQEQRLPRPEDQSPAPPPPPPSSATTSTAAPATPTHQVATVIANMDTLKTAFLPNLSMDPNVHVSPHYCPMCHQQFERPQHVADHMQLCHGITLNAQGAIATLDGGHPQAQQHPKLSHPCFNCDEKFGNAVDLDEHHRLAHQTPAFLSRCLMCSIYGIHSATQQPNEYKCTQCGSICTTAMLAAGQQGFMEQQEAAVTPDDQLPAMAPRDMRLTPEEQHHQQQLQAEHHHQQQHQQQQQQQQQQQELLEQQQREMQEQAQQQQVHHHQQDQDLAGDQVALKVPPLTVKLNKNANGGAIVSHPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPGVPAPASSGVLVGTQTVPADLAHKIRHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFRCGYCGRAFTVKDYLNKHLTTHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKLHPL", "length": 510, "molWeight": 56750, "crc64": "4C692B85157DE0AB", "md5": "CB946FF10B4D53456AA5F96CD9DAE77F"}}
{"primaryAccession": "P21396", "text": "This is Amine oxidase [flavin-containing] A protein, from Rat, contains 526 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P21396", "organism_name": "Rat", "protein_name": "Amine oxidase [flavin-containing] A", "length": 526, "firstPublicDate": "1991-05-01", "FUNCTION": "Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:18391214, PubMed:9162023), Preferentially oxidizes serotonin (PubMed:20493079), Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline (PubMed:18391214)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the flavin monoamine oxidase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADRQAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKDVPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC", "length": 526, "molWeight": 59508, "crc64": "381AE35D5A73E25B", "md5": "75828E089EFBA9C74F8ABE1424F56BB9"}}
{"primaryAccession": "P21926", "text": "This is CD9 antigen protein, from Human, contains 228 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P21926", "organism_name": "Human", "protein_name": "CD9 antigen", "length": 228, "firstPublicDate": "1991-05-01", "FUNCTION": "Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (PubMed:8478605, PubMed:14575715, PubMed:18541721), Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity), In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity), In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (PubMed:12796480), Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity), Acts as a receptor for PSG17 (By similarity), Involved in platelet activation and aggregation (PubMed:18541721), Regulates paranodal junction formation (By similarity), Involved in cell adhesion, cell motility and tumor metastasis (PubMed:8478605, PubMed:7511626)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the tetraspanin (TM4SF) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDTYNKLKTKDEPQRETLKAIHYALNCCGLAGGVEQFISDICPKKDVLETFTVKSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRNREMV", "length": 228, "molWeight": 25416, "crc64": "F68333E0C20611D8", "md5": "55A1FFAA80B3D208CF2A02F36F414BE0"}}
{"primaryAccession": "P22139", "text": "This is DNA-directed RNA polymerases I, II, and III subunit RPABC5 protein, from Baker's yeast, contains 70 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P22139", "organism_name": "Baker's yeast", "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "length": 70, "firstPublicDate": "1991-08-01", "FUNCTION": "DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively, Pol II is the central component of the basal RNA polymerase II transcription machinery, Pols are composed of mobile elements that move relative to each other, In Pol II, RBP10 is part of the core element with the central large cleft", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKFLRYNPLEKRD", "length": 70, "molWeight": 8278, "crc64": "E1F5733E8F466BE0", "md5": "1F58970E75358D74EFF5AA5851399EAB"}}
{"primaryAccession": "P22185", "text": "This is Ubiquinol oxidase 1, mitochondrial protein, from Voodoo lily, contains 349 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P22185", "organism_name": "Voodoo lily", "protein_name": "Ubiquinol oxidase 1, mitochondrial", "length": 349, "firstPublicDate": "1991-08-01", "FUNCTION": "Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation, May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures, In S,guttatum the alternative respiratory pathway is thermogenic", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the alternative oxidase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MMSSRLVGTALCRQLSHVPVPQYLPALRPTADTASSLLHGCSAAAPAQRAGLWPPSWFSPPRHASTLSAPAQDGGKEKAAGTAGKVPPGEDGGAEKEAVVSYWAVPPSKVSKEDGSEWRWTCFRPWETYQADLSIDLHKHHVPTTILDKLALRTVKALRWPTDIFFQRRYACRAMMLETVAAVPGMVGGVLLHLKSLRRFEHSGGWIRALLEEAENERMHLMTFMEVAQPRWYERALVLAVQGVFFNAYFLGYLLSPKFAHRVVGYLEEEAIHSYTEFLKDIDSGAIQDCPAPAIALDYWRLPQGSTLRDVVTVVRADEAHHRDVNHFASDVHYQDLELKTTPAPLGYH", "length": 349, "molWeight": 38931, "crc64": "6E70B2B7A858B273", "md5": "1E5D7CEEFAD86FE3F696DB91A418C76A"}}
{"primaryAccession": "P22509", "text": "This is rRNA 2'-O-methyltransferase fibrillarin protein, from Rat, contains 327 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P22509", "organism_name": "Rat", "protein_name": "rRNA 2'-O-methyltransferase fibrillarin", "length": 327, "firstPublicDate": "1991-08-01", "FUNCTION": "S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins, Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (By similarity), Site specificity is provided by a guide RNA that base pairs with the substrate (By similarity), Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity), Probably catalyzes 2'-O-methylation of U6 snRNAs in box C/D RNP complexes, U6 snRNA 2'-O-methylation is required for mRNA splicing fidelity, Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity), Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit, During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the methyltransferase superfamily, Fibrillarin family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKPGFSPRGGGFGGRGGFGDRGGRGGGRGGRGGFGGGRGGFGGGGRGRGGGGGGFRGRGGGGGRGGGFQSGGGRGRGGGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKAKN", "length": 327, "molWeight": 34222, "crc64": "0E22E63175808BAE", "md5": "141E5AE1F1A67541DD5C211387146EF7"}}
{"primaryAccession": "P22557", "text": "This is 5-aminolevulinate synthase, erythroid-specific, mitochondrial protein, from Human, contains 587 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P22557", "organism_name": "Human", "protein_name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "length": 587, "firstPublicDate": "1991-08-01", "FUNCTION": "Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products (PubMed:14643893), Catalytic activity is 65-75% of isoform 1 activity (PubMed:14643893)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGGDSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTDLPSSLVSVSLRKPFSGPQEQEQISGKVTHLIQNNMPGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA", "length": 587, "molWeight": 64633, "crc64": "FD821BE245C440B5", "md5": "B0CD70297A440B4074EB5FA2FF467D2D"}}
{"primaryAccession": "P23321", "text": "This is Oxygen-evolving enhancer protein 1-1, chloroplastic protein, from Mouse-ear cress, contains 332 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P23321", "organism_name": "Mouse-ear cress", "protein_name": "Oxygen-evolving enhancer protein 1-1, chloroplastic", "length": 332, "firstPublicDate": "1991-11-01", "FUNCTION": "Stabilizes the manganese cluster which is the primary site of water splitting", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the PsbO family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAASLQSTATFLQSAKIATAPSRGSSHLRSTQAVGKSFGLETSSARLTCSFQSDFKDFTGKCSDAVKIAGFALATSALVVSGASAEGAPKRLTYDEIQSKTYMEVKGTGTANQCPTIDGGSETFSFKPGKYAGKKFCFEPTSFTVKADSVSKNAPPEFQNTKLMTRLTYTLDEIEGPFEVASDGSVNFKEEDGIDYAAVTVQLPGGERVPFLFTVKQLDASGKPDSFTGKFLVPSYRGSSFLDPKGRGGSTGYDNAVALPAGGRGDEEELVKENVKNTAASVGEITLKVTKSKPETGEVIGVFESLQPSDTDLGAKVPKDVKIQGVWYGQLE", "length": 332, "molWeight": 35142, "crc64": "73174DDC09C11E5C", "md5": "926B0A16AD509971EE6E26E79223C10C"}}
{"primaryAccession": "P23685", "text": "This is Sodium/calcium exchanger 1 protein, from Dog, contains 970 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P23685", "organism_name": "Dog", "protein_name": "Sodium/calcium exchanger 1", "length": 970, "firstPublicDate": "1991-11-01", "FUNCTION": "Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:1700476, PubMed:1785844, PubMed:9486131, PubMed:17962412), Contributes to Ca(2+) transport during excitation-contraction coupling in muscle, In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum, SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline, Required for normal embryonic heart development and the onset of heart contractions (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2,A,19) family, SLC8 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLQLRLLPTFSMGCHLLAVVALLFSHVDLISAETEMEGEGNETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVAENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSALACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLYGQPVFRKVHAREHPIPSTVITIAEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGILTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF", "length": 970, "molWeight": 108004, "crc64": "BBDBCC584846AE08", "md5": "614608211786D2C48E8FEF03566F7B4B"}}
{"primaryAccession": "P25008", "text": "This is Cyclin-C protein, from Fruit fly, contains 267 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25008", "organism_name": "Fruit fly", "protein_name": "Cyclin-C", "length": 267, "firstPublicDate": "1992-03-01", "FUNCTION": "Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes, Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors, Binds to and activates cyclin-dependent kinase Cdk8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex, Required for leg and eye development and macrochaete specification or differentiation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the cyclin family, Cyclin C subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGNFWQSSHSQQWILDKPDLLRERQHDLLALNEDEYQKVFIFFANVIQVLGEQLKLRQQVIATATVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEFGVISNSRLISICQSAIKTKFSYAYAQEFPYRTNHILECEFYLLENLDCCLIVYQPYRPLLQLVQDMGQEDQLLTLSWRIVNDSLRTDVCLLYPPYQIAIACLQIACVILQKDATKQWFAELNVDLDKVQEIVRAIVNLYELWKDWKEKDEIQMLLSKIPKPKPPPQR", "length": 267, "molWeight": 31292, "crc64": "DA73CB7EA89149FE", "md5": "861994482461427E17116D58D41D845A"}}
{"primaryAccession": "P25046", "text": "This is Mediator of RNA polymerase II transcription subunit 19 protein, from Baker's yeast, contains 220 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25046", "organism_name": "Baker's yeast", "protein_name": "Mediator of RNA polymerase II transcription subunit 19", "length": 220, "firstPublicDate": "1992-05-01", "FUNCTION": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes, Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors, The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II, The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Mediator complex subunit 19 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASRVDETTVPSYYYYVDPETTYTYQQPNPLQDLISVYGLDDISRQVARTNLDGTKAVKLRKSYKNQIADLSGKFSTIPTRENGKGGQIAHILFQNNPDMMIQPPQQGQNMSEQQWREQLRNRDIALFQPPNFDWDLCSSVLSQFERSYPSEFANQNQGGAQAPFDIDDLAFDLDGTGKSQSGSNSGNNSKKRKNKSSGSSMATPTHSDSHEDMKRRRLE", "length": 220, "molWeight": 24857, "crc64": "1400C6554D233144", "md5": "D37E814F05725D1D1044E892EA38E9C3"}}
{"primaryAccession": "P25189", "text": "This is Myelin protein P0 protein, from Human, contains 248 amino acids, has 1 Ig-like V-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [30, 143], "description": "Ig-like V-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like V-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "P25189", "organism_name": "Human", "protein_name": "Myelin protein P0", "length": 248, "firstPublicDate": "1992-05-01", "FUNCTION": "Is an adhesion molecule necessary for normal myelination in the peripheral nervous system, It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the myelin P0 protein family", "domain_description": {"Ig-like V-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVLLLLLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDHSRSTKAVSEKKAKGLGESRKDKK", "length": 248, "molWeight": 27555, "crc64": "A93F4744DACB0D5E", "md5": "31F62B07879A37940DAA03F20DFC1041"}}
{"primaryAccession": "P25846", "text": "This is DNA mismatch repair protein MSH1, mitochondrial protein, from Baker's yeast, contains 959 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25846", "organism_name": "Baker's yeast", "protein_name": "DNA mismatch repair protein MSH1, mitochondrial", "length": 959, "firstPublicDate": "1992-05-01", "FUNCTION": "Important for mitochondrial DNA (mtDNA) stability and repair, Recognizes and binds to base-base and small insertion-deletion mismatches in mtDNA, ATP binding and hydrolysis is crucial for function, Binding to a mismatched base pair attenuates ATP hydrolysis, Also involved in proper sorting of mtDNA during mtDNA transmission", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the DNA mismatch repair MutS family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKHFFRLPTAFRPISRVSLRYSSTDTAQPKISKLKISFNKISESNSEKKDNLGSIDTRNCLSTQQDDKLSSTEPSKASLPPSLQYVRDLMDLYKDHVVLTQMGSFYELYFEQAIRYAPELNISLTNRAYSHGKVPFAGFPVHQLSRHLKMLVNNCGYSVTIAEQFKKKDVADNEANKFYRRVTRIVTPGTFIDEAFENLRENTYLLNIEFPENCMSQVADTSLKVGICWCDVSTGEIFVQQVYLRDLVSAITRIQPKEILLDERLLEFHIESGTWYPELVELKKFFIKYQKMPSQHRTIESFYGLFNLGGKEATERQLKIQFQTFTQKELAALRNTLIYVSNHLPDFSINFQIPQRQLATAIMQIDSRTSTALELHSTVRDNNKKGSLLSSIRRTVTPSGTRLLSQWLSGPSLDLKEIKKRQKIVAFFKDNRDITETLRTMLKKVNDLSRILQKFSFGRGEALELIQMARSLEVSREIRKYLLNNTSLMKATLKSQITQLTESLNFEKNLIDDILKFLNEEELAKSQDAKQNADVTRMLDIDVKDKKESNKDEIFELRDFIVNPSFNTKLRKLHDTYQGVWQKKTEYNALLKGFFVGDLGAKTFTLKERQNGEYALHVTGTASSLKKIDELISKSTEYHGSCFHILQKSSQTRWLSHKIWTDLGHELELLNLKIRNEEANIIDLFKRKFIDRSNEVRQVATTLGYLDTLSSFAVLANERNLVCPKVDESNKLEVVNGRHLMVEEGLSARSLETFTANNCELAKDNLWVITGPNMGGKSTFLRQNAIIVILAQIGCFVPCSKARVGIVDKLFSRVGSADDLYNEMSTFMVEMIETSFILQGATERSLAILDEIGRGTSGKEGISIAYATLKYLLENNQCRTLFATHFGQELKQIIDNKCSKGMSEKVKFYQSGITDLGGNNFCYNHKLKPGICTKSDAIRVAELAGFPMEALKEAREILG", "length": 959, "molWeight": 109409, "crc64": "F40985CB4D2ECFF1", "md5": "B5744A160538BA03463E54781CAA268A"}}
{"primaryAccession": "P25961", "text": "This is Parathyroid hormone/parathyroid hormone-related peptide receptor protein, from Rat, contains 591 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25961", "organism_name": "Rat", "protein_name": "Parathyroid hormone/parathyroid hormone-related peptide receptor", "length": 591, "firstPublicDate": "1992-05-01", "FUNCTION": "Receptor for parathyroid hormone and for parathyroid hormone-related peptide, The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGAARIAPSLALLLCCPVLSSAYALVDADDVFTKEEQIFLLHRAQAQCDKLLKEVLHTAANIMESDKGWTPASTSGKPRKEKASGKFYPESKENKDVPTGSRRRGRPCLPEWDNIVCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTIFGWGLPAVFVAVWVGVRATLANTGCWDLSSGHKKWIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVFMALPYTEVSGTLWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRAGLSLPLSPRLPPATTNGHSQLPGHAKPGAPATETETLPVTMAVPKDDGFLNGSCSGLDEEASGSARPPPLLQEEWETVM", "length": 591, "molWeight": 66261, "crc64": "21944F3051B9E9C1", "md5": "445B99F7313B4DE1BB6D149F22F14837"}}
{"primaryAccession": "P25976", "text": "This is Nucleolar transcription factor 1 protein, from Mouse, contains 765 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25976", "organism_name": "Mouse", "protein_name": "Nucleolar transcription factor 1", "length": 765, "firstPublicDate": "1992-05-01", "FUNCTION": "Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex, It binds specifically to the upstream control element", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKTLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQTTSPASKKPSQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLTEKKKAKYKAREAALKAQSERKPGGEREDRGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQRQYKVHLDLWVKSLSPQDRAAYKEYISNKRKNMTKLRGPNPKSSRTTLQSKSESEEDDDEEEEDDEEEEEEEEDDENGDSSEDGGDSSESSSEDESEDGDENDDDDDDEDDEDDDDEDEDNESEGSSSSSSSSGDSSDSGSN", "length": 765, "molWeight": 89509, "crc64": "006A20A7F968DB6A", "md5": "B2DCFD9933367D0D1105A11ECF251A7A"}}
{"primaryAccession": "P27091", "text": "This is Protein 60A protein, from Fruit fly, contains 455 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P27091", "organism_name": "Fruit fly", "protein_name": "Protein 60A", "length": 455, "firstPublicDate": "1992-08-01", "FUNCTION": "Required for the growth of imaginal tissues and for patterning of the adult wing", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the TGF-beta family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSGLRNTSEAVAVLASLGLGMVLLMFVATTPPAVEATQSGIYIDNGKDQTIMHRVLSEDDKLDVSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGCH", "length": 455, "molWeight": 51687, "crc64": "C8FA795556341F94", "md5": "DDA5982D440E1461660690C492A45C2F"}}
{"primaryAccession": "P27614", "text": "This is Carboxypeptidase S protein, from Baker's yeast, contains 576 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P27614", "organism_name": "Baker's yeast", "protein_name": "Carboxypeptidase S", "length": 576, "firstPublicDate": "1992-08-01", "FUNCTION": "Necessary for use of certain peptides as sole nitrogen source, May also cleave intracellularly generated peptides to recycle amino acids for protein synthesis", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the peptidase M20A family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MIALPVEKAPRKSLWQRHRAFISGIVALIIIGTFFLTSGLHPAPPHEAKRPHHGKGPMHSPKCEKIEPLSPSFKHSVDTILHDPAFRNSSIEKLSNAVRIPTVVQDKNPNPADDPDFYKHFYELHDYFEKTFPNIHKHLKLEKVNELGLLYTWEGSDPDLKPLLLMAHQDVVPVNNETLSSWKFPPFSGHYDPETDFVWGRGSNDCKNLLIAEFEAIEQLLIDGFKPNRTIVMSLGFDEEASGTLGAASLASFLHERYGDDGIYSIIDEGEGIMEVDKDVFVATPINAEKGYVDFEVSILGHGGHSSVPPDHTTIGIASELITEFEANPFDYEFEFDNPIYGLLTCAAEHSKSLSKDVKKTILGAPFCPRRKDKLVEYISNQSHLRSLIRTTQAVDIINGGVKANALPETTRFLINHRINLHSSVAEVFERNIEYAKKIAEKYGYGLSKNGDDYIIPETELGHIDITLLRELEPAPLSPSSGPVWDILAGTIQDVFENGVLQNNEEFYVTTGLFSGNTDTKYYWNLSKNIYRFVGSIIDIDLLKTLHSVNEHVDVPGHLSAIAFVYEYIVNVNEYA", "length": 576, "molWeight": 64597, "crc64": "5CBB536D421B5F70", "md5": "5899D2644A5EC265D2171667E12C4E94"}}
{"primaryAccession": "P27661", "text": "This is Histone H2AX protein, from Mouse, contains 143 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P27661", "organism_name": "Mouse", "protein_name": "Histone H2AX", "length": 143, "firstPublicDate": "1992-08-01", "FUNCTION": "Variant histone H2A which replaces conventional H2A in a subset of nucleosomes, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKSSATVGPKAPAVGKKASQASQEY", "length": 143, "molWeight": 15143, "crc64": "A3683760C13CC2B9", "md5": "C55C9C7C2A9DBEA3397E201612601271"}}
{"primaryAccession": "P27882", "text": "This is Mitochondrial FAD-linked sulfhydryl oxidase ERV1 protein, from Baker's yeast, contains 189 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P27882", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial FAD-linked sulfhydryl oxidase ERV1", "length": 189, "firstPublicDate": "1992-08-01", "FUNCTION": "FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation, Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space (IMS), Forms a redox cycle with MIA40 that involves a disulfide relay system, Important for maintaining the cysteine residues in MIA40 in an oxidized state, Reduced ERV1 is reoxidized by cytochrome c, Required for the maturation of cytoplasmic, but not of mitochondrial Fe/S proteins", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKAIDKMTDNPPQEGLSGRKIIYDEDGKPCRSCNTLLDFQYVTGKISNGLKNLSSNGKLAGTGALTGEASELMPGSRTYRKVDPPDVEQLGRSSWTLLHSVAASYPAQPTDQQKGEMKQFLNIFSHIYPCNWCAKDFEKYIRENAPQVESREELGRWMCEAHNKVNKKLRKPKFDCNFWEKRWKDGWDE", "length": 189, "molWeight": 21639, "crc64": "83DADA0DB1DF17CC", "md5": "1684D48E0ADDBBFF62DD66CD4EBEAF8F"}}
{"primaryAccession": "P28037", "text": "This is Cytosolic 10-formyltetrahydrofolate dehydrogenase protein, from Rat, contains 902 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P28037", "organism_name": "Rat", "protein_name": "Cytosolic 10-formyltetrahydrofolate dehydrogenase", "length": 902, "firstPublicDate": "1992-08-01", "FUNCTION": "Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:1848231, PubMed:10585460, PubMed:7822273, PubMed:17884809, PubMed:17302434), May also have an NADP(+)-dependent aldehyde dehydrogenase activity towards formaldehyde, acetaldehyde, propionaldehyde, and benzaldehyde (PubMed:1848231)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "In the C-terminal section; belongs to the aldehyde dehydrogenase family, ALDH1L subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKIAVIGQSLFGQEVYCQLRKEGHEVVGVFTIPDKDGKADPLGLEAEKDGVPVFKFPRWRARGQALPEVVAKYQALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGTAPRCPQSEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACGQKLTFFNSTLNTSGLSTQGEALPIPGAHRPGVVTKAGLILFGNDDRMLLVKNIQLEDGKMMPASQFFKGSASSDLELTEAELATAEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCDGLELENEDVYMATTFRGFIQLLVRKLRGEDDESECVINYVEKAVNKLTLQMPYQLFIGGEFVDAEGSKTYNTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGLWGKINARDRGRLLYRLADVMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEESIHNQFVQKVVEEVEKMKIGNPLERDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQVPRPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRIKTVTFEY", "length": 902, "molWeight": 98874, "crc64": "562A8CBD73D6474A", "md5": "ACC4DD36DA48D4A051DAFA2D77355299"}}
{"primaryAccession": "P28241", "text": "This is Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial protein, from Baker's yeast, contains 369 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P28241", "organism_name": "Baker's yeast", "protein_name": "Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial", "length": 369, "firstPublicDate": "1992-12-01", "FUNCTION": "Performs an essential role in the oxidative function of the citric acid cycle, Also binds RNA; specifically to the 5'-untranslated leaders of mitochondrial mRNAs", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLRNTFFRNTSRRFLATVKQPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL", "length": 369, "molWeight": 39739, "crc64": "3A48C999776CE373", "md5": "E2FAD21EBC1E45FB16FBF9A441430413"}}
{"primaryAccession": "P28263", "text": "This is Ubiquitin-conjugating enzyme E2-24 kDa protein, from Baker's yeast, contains 218 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P28263", "organism_name": "Baker's yeast", "protein_name": "Ubiquitin-conjugating enzyme E2-24 kDa", "length": 218, "firstPublicDate": "1992-12-01", "FUNCTION": "Catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:1869573) (By similarity), Required for the adaptation to the presence of glucose in the growth medium; mediates the degradation of enzymes involved in gluconeogenesis when cells are shifted to glucose-containing medium (PubMed:9737955, PubMed:10811607, PubMed:12686616), Required for proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBP1) (PubMed:9737955, PubMed:10811607, PubMed:12686616, PubMed:28126757)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ubiquitin-conjugating enzyme family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSSKRRIETDVMKLLMSDHQVDLINDSMQEFHVKFLGPKDTPYENGVWRLHVELPDNYPYKSPSIGFVNKIFHPNIDIASGSICLDVINSTWSPLYDLINIVEWMIPGLLKEPNGSDPLNNEAATLQLRDKKLYEEKIKEYIDKYATKEKYQQMFGGDNDSDDSDSGGDLQEEDSDSDEDMDGTGVSSGDDSVDELSEDLSDIDVSDDDDYDEVANQ", "length": 218, "molWeight": 24633, "crc64": "24FFAD8B4679CE6F", "md5": "4BC369C2FF3AE9148834FD9E61C805B3"}}
{"primaryAccession": "P28272", "text": "This is Dihydroorotate dehydrogenase (fumarate) protein, from Baker's yeast, contains 314 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P28272", "organism_name": "Baker's yeast", "protein_name": "Dihydroorotate dehydrogenase (fumarate)", "length": 314, "firstPublicDate": "1992-12-01", "FUNCTION": "Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor, Molecular oxygen can replace fumarate in vitro, Does not use oxaloacetate or NAD or NADP as electron acceptors", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the dihydroorotate dehydrogenase family, Type 1 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTASLTTKFLNNTYENPFMNASGVHCMTTQELDELANSKAGAFITKSATTLEREGNPEPRYISVPLGSINSMGLPNEGIDYYLSYVLNRQKNYPDAPAIFFSVAGMSIDENLNLLRKIQDSEFNGITELNLSCPNVPGKPQVAYDFDLTKETLEKVFAFFKKPLGVKLPPYFDFAHFDIMAKILNEFPLAYVNSINSIGNGLFIDVEKESVVVKPKNGFGGIGGEYVKPTALANVRAFYTRLRPEIKVIGTGGIKSGKDAFEHLLCGASMLQIGTELQKEGVKIFERIEKELKDIMEAKGYTSIDQFRGKLNSI", "length": 314, "molWeight": 34801, "crc64": "0F1FF9BDA7F8D68E", "md5": "5966F863ACC83CEF93A769FDF5F21C9A"}}
{"primaryAccession": "P28288", "text": "This is ATP-binding cassette sub-family D member 3 protein, from Human, contains 659 amino acids, is membrane-bound, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P28288", "organism_name": "Human", "protein_name": "ATP-binding cassette sub-family D member 3", "length": 659, "firstPublicDate": "1992-12-01", "FUNCTION": "Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation (PubMed:11248239, PubMed:25168382, PubMed:24333844, PubMed:29397936), Has fatty acyl-CoA thioesterase and ATPase activities (PubMed:29397936), Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes (By similarity), Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation (PubMed:25944712, PubMed:24333844)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the ABC transporter superfamily, ABCD family, Peroxisomal fatty acyl CoA transporter (TC 3,A,1,203) subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS", "length": 659, "molWeight": 75476, "crc64": "2CA976FEB6EB6217", "md5": "062D06437063037C67458C75D57EBDEA"}}
{"primaryAccession": "P29352", "text": "This is Tyrosine-protein phosphatase non-receptor type 22 protein, from Mouse, contains 802 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P29352", "organism_name": "Mouse", "protein_name": "Tyrosine-protein phosphatase non-receptor type 22", "length": 802, "firstPublicDate": "1992-12-01", "FUNCTION": "Acts as negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TCRz/CD3 complex, as well as ZAP70, VAV, VCP and other key signaling molecules (By similarity), Associates with and probably dephosphorylates CBL (By similarity), Dephosphorylates LCK at its activating 'Tyr-394' residue (By similarity), Dephosphorylates ZAP70 at its activating 'Tyr-492' residue (By similarity), Dephosphorylates the immune system activator SKAP2 (By similarity), Positively regulates toll-like receptor (TLR)-induced type 1 interferon production (PubMed:23871208), Promotes host antiviral responses mediated by type 1 interferon (PubMed:23871208), Regulates NOD2-induced pro-inflammatory cytokine secretion and autophagy (PubMed:23991106), Acts as an activator of NLRP3 inflammasome assembly by mediating dephosphorylation of 'Tyr-861' of NLRP3 (PubMed:27043286), Dephosphorylates phospho-anandamide (p-AEA), an endocannabinoid to anandamide (also called N-arachidonoylethanolamide) (PubMed:16938887)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein-tyrosine phosphatase family, Non-receptor class 4 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDQREILQQLLKEAQKKKLNSEEFASEFLKLKRQSTKYKADKIYPTTVAQRPKNIKKNRYKDILPYDHSLVELSLLTSDEDSSYINASFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYRILVIVMACMEFEMGKKKCERYWAEPGETQLQFGPFSISCEAEKKKSDYKIRTLKAKFNNETRIIYQFHYKNWPDHDVPSSIDPILQLIWDMRCYQEDDCVPICIHCSAGCGRTGVICAVDYTWMLLKDGIIPKNFSVFNLIQEMRTQRPSLVQTQEQYELVYSAVLELFKRHMDVISDNHLGREIQAQCSIPEQSLTVEADSCPLDLPKNAMRDVKTTNQHSKQGAEAESTGGSSLGLRTSTMNAEEELVLHSAKSSPSFNCLELNCGCNNKAVITRNGQARASPVVGEPLQKYQSLDFGSMLFGSCPSALPINTADRYHNSKGPVKRTKSTPFELIQQRKTNDLAVGDGFSCLESQLHEHYSLRELQVQRVAHVSSEELNYSLPGACDASCVPRHSPGALRVHLYTSLAEDPYFSSSPPNSADSKMSFDLPEKQDGATSPGALLPASSTTSFFYSNPHDSLVMNTLTSFSPPLNQETAVEAPSRRTDDEIPPPLPERTPESFIVVEEAGEPSPRVTESLPLVVTFGASPECSGTSEMKSHDSVGFTPSKNVKLRSPKSDRHQDGSPPPPLPERTLESFFLADEDCIQAQAVQTSSTSYPETTENSTSSKQTLRTPGKSFTRSKSLKIFRNMKKSVCNSSSPSKPTERVQPKNSSSFLNFGFGNRFSKPKGPRNPPSAWNM", "length": 802, "molWeight": 89714, "crc64": "0F1E45339BD4613E", "md5": "17AA5C1C1F66DFEA637F5D673D252171"}}
{"primaryAccession": "P30082", "text": "This is Glucagon receptor protein, from Rat, contains 485 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30082", "organism_name": "Rat", "protein_name": "Glucagon receptor", "length": 485, "firstPublicDate": "1993-04-01", "FUNCTION": "G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis, Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis, Plays an important role in mediating the responses to fasting, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase, Promotes activation of adenylate cyclase, Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLLTQLHCPYLLLLLVVLSCLPKAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQSWRDASQCQMDDDEIEVQKGVAKMYSSYQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAVAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSITTFSEKSFFSLYLCIGWGSPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVLLAILINFFIFVRIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSTKLFFDLFFSSFQGLLVAVLYCFLNKEVQAELLRRWRRWQEGKALQEERMASSHGSHMAPAGTCHGDPCEKLQLMSAGSSSGTGCEPSAKTSLASSLPRLADSPT", "length": 485, "molWeight": 55038, "crc64": "91AC67D7A4F5090E", "md5": "666E01ABE32FCE51D13623AC6805E0C0"}}
{"primaryAccession": "P30181", "text": "This is DNA topoisomerase 1 alpha protein, from Mouse-ear cress, contains 916 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30181", "organism_name": "Mouse-ear cress", "protein_name": "DNA topoisomerase 1 alpha", "length": 916, "firstPublicDate": "1993-04-01", "FUNCTION": "Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex, Introduces a single-strand break via transesterification at a target site in duplex DNA, The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand, The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils, Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity), Can complement a TOP1-deficient yeast mutant (PubMed:16669064), Plays a critical role in the maintenance of a regular pattern of organ initiation, Topoisomerases I enzymes (TOP1A and TOP1B) are essential for plant survival (PubMed:12215507), Functions together with the stem cell maintenance gene WUSCHEL (WUS) in stem cell regulation, Required to maintain developmentally regulated gene repression, Functions synergistically with chromatin remodeling factors (PubMed:20228247), Is required for the repression of WUS expression in flower development, Plays a role in polycomb group (PcG) protein-mediated histone H3 trimethylation on 'Lys-27' (H3K27me3) at the WUS gene locus, H3K27me3 induces transcriptional repression of WUS, May assist AGAMOUS (AG) in recruiting PcG proteins to WUS locus, Reduces nucleosome density, especially at genes that are targets of PcG proteins (PubMed:25070639), Plays a role in epigenetic silencing, Involved in RNA-directed DNA methylation (RdDM) by promoting Pol V transcription to generate long non-coding RNA transcripts, Is dispensable for Pol IV-mediated small interfering RNA (siRNA) biogenesis, Promotes transposable element (TE) silencing at endogenous RdDM target loci through histone H3 dimethylation of 'Lys-9' (H3K9me2), Promotes the production of Pol V-dependent long non-coding transcripts that facilitate the recruitment of siRNA-AGO4 and AGO4 occupancy at TEs (PubMed:24992598)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the type IB topoisomerase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGTETVSKPVMDNGSGDSDDDKPLAFKRNNTVASNSNQSKSNSQRSKAVPTTKVSPMRSPVTSPNGTTPSNKTSIVKSSMPSSSSKASPAKSPLRNDMPSTVKDRSQLQKDQSECKIEHEDSEDDRPLSSILSGNKGPTSSRQVSSPQPEKKNNGDRPLDRASRIIKDESDDETPISSMFRKKIDSGMSGGNQLSNDEKKPLVQKLHQNGSTVKNEVPNGKVLGKRPLEKNSSADQSSLKKAKISASPTSVKMKQDSVKKEIDDKGRVLVSPKMKAKQLSTREDGTDDDDDDDVPISKRFKSDSSNSNTSSAKPKAVKLNSTSSAAKPKARNVVSPRSRAMTKNTKKVTKDSKYSTSSKSSPSSGDGQKKWTTLVHNGVIFPPPYKPHGIKILYKGKPVDLTIEQEEVATMFAVMRETDYYTKPQFRENFWNDWRRLLGKKHVIQKLDDCDFTPIYEWHLEEKEKKKQMSTEEKKALKEEKMKQEEKYMWAVVDGVKEKIGNFRVEPPGLFRGRGEHPKMGKLKKRIHPCEITLNIGKGAPIPECPIAGERWKEVKHDNTVTWLAFWADPINPKEFKYVFLGAGSSLKGLSDKEKYEKARNLTDHIDNIRTTYTKNFTAKDVKMRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKIKFDFLGKDSIQYVNTVEVEPLVYKAIGQFQAGKSKTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKGKPPLEGSDGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMDVEPEYRFSRR", "length": 916, "molWeight": 102799, "crc64": "84BF47913F14454F", "md5": "8DA09B3D7B93FA3135DA63A503A028C9"}}
{"primaryAccession": "P30307", "text": "This is M-phase inducer phosphatase 3 protein, from Human, contains 473 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30307", "organism_name": "Human", "protein_name": "M-phase inducer phosphatase 3", "length": 473, "firstPublicDate": "1993-04-01", "FUNCTION": "Functions as a dosage-dependent inducer in mitotic control, Tyrosine protein phosphatase required for progression of the cell cycle, When phosphorylated, highly effective in activating G2 cells into prophase, Directly dephosphorylates CDK1 and activates its kinase activity", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MPI phosphatase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANLSILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMKCSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP", "length": 473, "molWeight": 53365, "crc64": "0658A1F1B9B8996A", "md5": "004CEF7B0DAE937E6D722817C17ED889"}}
{"primaryAccession": "P30429", "text": "This is Cell death protein 4 protein, from Caenorhabditis elegans, contains 571 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30429", "organism_name": "Caenorhabditis elegans", "protein_name": "Cell death protein 4", "length": 571, "firstPublicDate": "1993-04-01", "FUNCTION": "Prevents programmed cell death", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLARVVSDTDDSHSITDFINRVLSRSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVDICSNEEEQLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNVSVPERHIPSHFQKFRRSSASEMYPKTTEETVIRPEDFPKFMQLHQKFYDSLKNFACC", "length": 571, "molWeight": 65336, "crc64": "6BE9893946B79E6C", "md5": "622CD403183E1BB79BEB28F41B208F46"}}
{"primaryAccession": "P30518", "text": "This is Vasopressin V2 receptor protein, from Human, contains 371 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30518", "organism_name": "Human", "protein_name": "Vasopressin V2 receptor", "length": 371, "firstPublicDate": "1993-04-01", "FUNCTION": "Receptor for arginine vasopressin, The activity of this receptor is mediated by G proteins which activate adenylate cyclase, Involved in renal water reabsorption", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSS", "length": 371, "molWeight": 40279, "crc64": "1F87D20A3C0ECB0D", "md5": "AD085CC7B2E4231EE988E9A7A555A3D6"}}
{"primaryAccession": "P30536", "text": "This is Translocator protein protein, from Human, contains 169 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30536", "organism_name": "Human", "protein_name": "Translocator protein", "length": 169, "firstPublicDate": "1993-04-01", "FUNCTION": "Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity), Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial, It is apparently not required for steroid hormone biosynthesis, Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the TspO/BZRP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE", "length": 169, "molWeight": 18828, "crc64": "6DD741BF99AB89D9", "md5": "DF044FA41FFA93FF570097081254F1E4"}}
{"primaryAccession": "P30543", "text": "This is Adenosine receptor A2a protein, from Rat, contains 410 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30543", "organism_name": "Rat", "protein_name": "Adenosine receptor A2a", "length": 410, "firstPublicDate": "1993-04-01", "FUNCTION": "Receptor for adenosine (By similarity), The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:23994616)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS", "length": 410, "molWeight": 44999, "crc64": "D87B256CD2336BAC", "md5": "FF6F104B125CDB6EFAC0F0F3B66EC58E"}}
{"primaryAccession": "P30936", "text": "This is Somatostatin receptor type 3 protein, from Rat, contains 428 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30936", "organism_name": "Rat", "protein_name": "Somatostatin receptor type 3", "length": 428, "firstPublicDate": "1993-07-01", "FUNCTION": "Receptor for somatostatin-14 and -28, This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAVTYPSSVPTTLDPGNASSAWPLDTSLGNASAGTSLAGLAVSGILISLVYLVVCVVGLLGNSLVIYVVLRHTSSPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARMVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRTAFIIYTAALGFFGPLLVICLCYLLIVVKVRSTTRRVRAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRVRSQEPGSGPPEKTEEEEDEEEEERREEEERRMQRGQEMNGRLSQIAQPGPSGQQQRPCTGTAKEQQLLPQEATAGDKASTLSHL", "length": 428, "molWeight": 47151, "crc64": "BE0AA948840A9E9D", "md5": "3D7A626EF360DF102B7057EE509018A7"}}
{"primaryAccession": "P30974", "text": "This is Tachykinin-like peptides receptor 86C protein, from Fruit fly, contains 504 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30974", "organism_name": "Fruit fly", "protein_name": "Tachykinin-like peptides receptor 86C", "length": 504, "firstPublicDate": "1993-07-01", "FUNCTION": "Receptor for tachykinin-like peptides", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSEIVDTELLVNCTILAVRRFELNSIVNTTLLGSLNRTEVVSLLSSIIDNRDNLESINEAKDFLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNLSIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLKRRTSRRKVRIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDGRYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFIAIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLGFYWLAMSNAMVNPLIYYWMNKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKNSSNRHTRAETKSQWKRSTMETQIQQAPVTSSCREQRSAQQQQPPGSGTNRAAVECIMERPADGSSSPLCLSINNSIGERQRVKIKYISCDEDNNPVELSPKQM", "length": 504, "molWeight": 58020, "crc64": "723C9622F3B663B9", "md5": "822542651173D069D234564EBEB6A6E5"}}
{"primaryAccession": "P30975", "text": "This is Tachykinin-like peptides receptor 99D protein, from Fruit fly, contains 519 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30975", "organism_name": "Fruit fly", "protein_name": "Tachykinin-like peptides receptor 99D", "length": 519, "firstPublicDate": "1993-07-01", "FUNCTION": "Receptor for tachykinin-like peptides", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MENRSDFEADDYGDISWSNWSNWSTPAGVLFSAMSSVLSASNHTPLPDFGQELALSTSSFNHSQTLSTDLPAVGDVEDAAEDAAASMETGSFAFVVPWWRQVLWSILFGGMVIVATGGNLIVVWIVMTTKRMRTVTNYFIVNLSIADAMVSSLNVTFNYYYMLDSDWPFGEFYCKLSQFIAMLSICASVFTLMAISIDRYVAIIRPLQPRMSKRCNLAIAAVIWLASTLISCPMMIIYRTEEVPVRGLSNRTVCYPEWPDGPTNHSTMESLYNILIIILTYFLPIVSMTVTYSRVGIELWGSKTIGECTPRQVENVRSKRRVVKMMIVVVLIFAICWLPFHSYFIITSCYPAITEAPFIQELYLAIYWLAMSNSMYNPIIYCWMNSRFRYGFKMVFRWCLFVRVGTEPFSRRENLTSRYSCSGSPDHNRIKRNDTQKSILYTCPSSPKSHRISHSGTGRSATLRNSLPAESLSSGGSGGGGHRKRLSYQQEMQQRWSGPNSATAVTNSSSTANTTQLLS", "length": 519, "molWeight": 58396, "crc64": "57105170D4CA5AA5", "md5": "244EF57E995270CFD3D2DBF7ADEB818F"}}
{"primaryAccession": "P30989", "text": "This is Neurotensin receptor type 1 protein, from Human, contains 418 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30989", "organism_name": "Human", "protein_name": "Neurotensin receptor type 1", "length": 418, "firstPublicDate": "1993-07-01", "FUNCTION": "G-protein coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:8381365, PubMed:21725197, PubMed:23140271), Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system, Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis (PubMed:21725197)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family, Neurotensin receptor subfamily, NTSR1 sub-subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY", "length": 418, "molWeight": 46259, "crc64": "471AD1C49D29C2C8", "md5": "6C0CB39AE435B4DCC927F1802B4E87D1"}}
{"primaryAccession": "P31361", "text": "This is POU domain, class 3, transcription factor 3 protein, from Mouse, contains 497 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P31361", "organism_name": "Mouse", "protein_name": "POU domain, class 3, transcription factor 3", "length": 497, "firstPublicDate": "1993-07-01", "FUNCTION": "Transcription factor that acts synergistically with SOX11 and SOX4 (By similarity), Plays a role in neuronal development, Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3')", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the POU transcription factor family, Class-3 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATAASNPYLPGNSLLTAGSIVHSDAAGAGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGREDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGAGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSADTPPPHHGLQTSVQ", "length": 497, "molWeight": 50200, "crc64": "4B1860BEED53F8B0", "md5": "59200A2100050D4A13A624CEABC0472B"}}
{"primaryAccession": "P32259", "text": "This is Mediator of RNA polymerase II transcription subunit 16 protein, from Baker's yeast, contains 974 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32259", "organism_name": "Baker's yeast", "protein_name": "Mediator of RNA polymerase II transcription subunit 16", "length": 974, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes, Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors, The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II, The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Mediator complex subunit 16 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMLGEHLMSWSKTGIIAYSDSQSSNANICLTFLESINGINWRFHTPQKYVLHPQLHEVQYQESSSTLSTHSTTTSVNGSTTAGVGSTPNFGGNSNKSPPQFFYNISSIHWNNWFSLPGDMLAVCDELGNMTMLITGQRPDRATTYEKLTMVFQDNVYKIYNHVMPLKPVDKLKPMNIERKQTRKEYNTSILEFRWLTSSKSVIVSQFCAFDSSSNTYRSRAQQVPPYGVYHPPFIKYACLAIRKNGQIDFWYQFSNSKDHKKITLQLLDTSNQRFKDLQWLEFARITPMNDDQCMLITTYSKLSKNISFYKLHVNWNLNATKPNVLNDPSLKIQFILSTTLDPTDDEGHVLKLENLHVVSKSSIEKDPSPEILVLYNVCDTSKSLVKRYRLAPTQLSAEYLVILKPDLNIDRNNSTNQIFQSRRYNLRRHSDIVLDKKVTLITSEMFDAFVSFYFEDGTIESYNQNDWKLETERLISQSQLGKFKNIIASPLSAGFNYGKLPLPPSVEWMKVSPSMCGVIVKQYNKKWPQFYAAVQKNYADPEKDSINATALAFGYVKSLHKQISAEDLTIAAKTHILRISFLDRKRAKEFITTLLKSLYSFFNISPDAPKEIMDKIITSRPLQKIMLLQLELGSCFSQENIEEMARVILYLKNVLFAFNGVARNFHFAIEQISNNSNQQQNPKLFQTIFSKQDLIHSLIPVAKWFVKFITYLTQEILILINDPTNKEYTLVHGIFGAKMSRTLILSILNEIKKVTQIVAKFPETSYPILNESSTFLKLVLSESPVDFEKFETFLVDVNNKFIALCEQQPSQEREFSLLVKAEIPPEYAKVGDFLLQYANNAVISHANAAAVYFADTSGLKISNSEFFNPEIFHLLQPLEEGLIIDTDKLPIKNRTSKSFSKLLYDDVTCDKLSVSEISDGKLKRCSRCGSVTRAGNIISSDKTIVPTSIQTKRWPTMYTRLCICSGMLFEMDG", "length": 974, "molWeight": 111297, "crc64": "12ECF5E4CDC05A8E", "md5": "58564B3D182ABC0E226A8D7FD4D21D06"}}
{"primaryAccession": "P32288", "text": "This is Glutamine synthetase protein, from Baker's yeast, contains 370 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32288", "organism_name": "Baker's yeast", "protein_name": "Glutamine synthetase", "length": 370, "firstPublicDate": "1993-10-01", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the glutamine synthetase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAEASIEKTQILQKYLELDQRGRIIAEYVWIDGTGNLRSKGRTLKKRITSIDQLPEWNFDGSSTNQAPGHDSDIYLKPVAYYPDPFRRGDNIVVLAACYNNDGTPNKFNHRHEAAKLFAAHKDEEIWFGLEQEYTLFDMYDDVYGWPKGGYPAPQGPYYCGVGAGKVYARDMIEAHYRACLYAGLEISGINAEVMPSQWEFQVGPCTGIDMGDQLWMARYFLHRVAEEFGIKISFHPKPLKGDWNGAGCHTNVSTKEMRQPGGMKYIEQAIEKLSKRHAEHIKLYGSDNDMRLTGRHETASMTAFSSGVANRGSSIRIPRSVAKEGYGYFEDRRPASNIDPYLVTGIMCETVCGAIDNADMTKEFERESS", "length": 370, "molWeight": 41766, "crc64": "43139C40E97DB34D", "md5": "BA8A5F574E7F3BC0AB723A9F1FE852BB"}}
{"primaryAccession": "P32316", "text": "This is Acetyl-CoA hydrolase protein, from Baker's yeast, contains 526 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32316", "organism_name": "Baker's yeast", "protein_name": "Acetyl-CoA hydrolase", "length": 526, "firstPublicDate": "1993-10-01", "FUNCTION": "Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation, It may be involved in overall regulation of acetylation during melatonin synthesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the acetyl-CoA hydrolase/transferase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTISNLLKQRVRYAPYLKKVKEAHELIPLFKNGQYLGWSGFTGVGTPKAVPEALIDHVEKNNLQGKLRFNLFVGASAGPEENRWAEHDMIIKRAPHQVGKPIAKAINQGRIEFFDKHLSMFPQDLTYGFYTRERKDNKILDYTIIEATAIKEDGSIVPGPSVGGSPEFITVSDKVIIEVNTATPSFEGIHDIDMPVNPPFRKPYPYLKVDDKCGVDSIPVDPEKVVAIVESTMRDQVPPNTPSDDMSRAIAGHLVEFFRNEVKHGRLPENLLPLQSGIGNIANAVIEGLAGAQFKHLTVWTEVLQDSFLDLFENGSLDYATATSVRLTEKGFDRAFANWENFKHRLCLRSQVVSNNPEMIRRLGVIAMNTPVEVDIYAHANSTNVNGSRMLNGLGGSADFLRNAKLSIMHAPSARPTKVDPTGISTIVPMASHVDQTEHDLDILVTDQGLADLRGLSPKERAREIINKCAHPDYQALLTDYLDRAEHYAKKHNCLHEPHMLKNAFKFHTNLAEKGTMKVDSWEPVD", "length": 526, "molWeight": 58712, "crc64": "7133A291F18AA1E4", "md5": "7CAADE826A59E02CBF95445EC9953DF7"}}
{"primaryAccession": "P32335", "text": "This is Protein MSS51, mitochondrial protein, from Baker's yeast, contains 436 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32335", "organism_name": "Baker's yeast", "protein_name": "Protein MSS51, mitochondrial", "length": 436, "firstPublicDate": "1993-10-01", "FUNCTION": "Has a dual role in the assembly of cytochrome oxidase subunit 1 (COX1), It has a regulative function on COX1 synthesis, acting as a translational activator specific for the COX1 mRNA, and it also binds to newly synthesized COX1 protein, Together with COX14, may act as a chaperone that binds efficiently unassembled COX1 and prevents it from unproductive aggregation, When bound to COX1, MSS51 is unable to interact with the COX1 mRNA and translation is halted, This may be a feedback control that ensures that COX1 is only produced as long as potentially harmful assembly intermediates are not accumulating", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MSS51 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTVLYAPSGATQLYFHLLRKSPHNRLVVSHQTRRHLMGFVRNALGLDPPPSPEDPTPENRFHPWDQSPSVDLRERAAKIRTLAHCPVTGKDINYTCPLSGIPTHHSREAWEMDKAYHDSKKYEILKKVNIYEHDLRSGRPFPEFDFPQQQGYDKAVNLTNWDLFFYTRSFYSMDTEFQLAAVTKMLSYPITIGSLLHKFSPYSLNPKGPITLEGLKSLAALRYTLYPLENRSLPTTTKNRAMRIFILGARAEAQLPGHVWKQLQFLFPEQSFEIHFIGPECLYKRDKQEYVKSTTPVVQRVDETLKFIYRTNFFEVFHEAQDFFPYDPYMDVFFTFHPGYASPESHGSWMGETMKALLETKCAIFTTGFNKKDLTDDINLVKSKYGKEMDVLMEPVRNVFGSTKWELNDMNPQEVYQFNMYIAGFRGKRYHTIKRQ", "length": 436, "molWeight": 50880, "crc64": "6A55BF160FE1D7DE", "md5": "AE1E60944F1F32D820EB7EA485250F57"}}
{"primaryAccession": "P32340", "text": "This is Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial protein, from Baker's yeast, contains 513 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32340", "organism_name": "Baker's yeast", "protein_name": "Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial", "length": 513, "firstPublicDate": "1993-10-01", "FUNCTION": "Catalyzes the oxidation of NADH generated inside the Mitochondrion", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the NADH dehydrogenase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLSKNLYSNKRLLTSTNTLVRFASTRSTGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL", "length": 513, "molWeight": 57250, "crc64": "E3A43D75A1ADCF3B", "md5": "2248311F98FF4E591E75C6451ADA6B9A"}}
{"primaryAccession": "P32354", "text": "This is Minichromosome maintenance protein 10 protein, from Baker's yeast, contains 571 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32354", "organism_name": "Baker's yeast", "protein_name": "Minichromosome maintenance protein 10", "length": 571, "firstPublicDate": "1993-10-01", "FUNCTION": "Required for DNA synthesis, Required for entry into or completion of S phase, Involved in DNA replication and seems to participate in the activation of the pre-replication complex (pre-RC) and in transcription elongation, May play a role as a key coordinator in assembling the replication fork, Proposed to function at replication origins following the binding of the MCM2-7 complex prior to the recruitment of CDC45, Probably is required to stimulate phosphorylation of the MCM2-7 complex by the CDC7-DBF4 kinase complex, May recruit the DNA polymerase alpha:primase complex to replication origins and is required to maintain it on chromatin independently of CDC45, May also play a role in transcriptional silencing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCM10 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNDPREILAVDPYNNITSDEEDEQAIARELEFMERKRQALVERLKRKQEFKKPQDPNFEAIEVPQSPTKNRVKVGSHNATQQGTKFEGSNINEVRLSQLQQQPKPPASTTTYFMEKFQNAKKNEDKQIAKFESMMNARVHTFSTDEKKYVPIITNELESFSNLWVKKRYIPEDDLKRALHEIKILRLGKLFAKIRPPKFQEPEYANWATVGLISHKSDIKFTSSEKPVKFFMFTITDFQHTLDVYIFGKKGVERYYNLRLGDVIAILNPEVLPWRPSGRGNFIKSFNLRISHDFKCILEIGSSRDLGWCPIVNKKTHKKCGSPINISLHKCCDYHREVQFRGTSAKRIELNGGYALGAPTKVDSQPSLYKAKGENGFNIIKGTRKRLSEEEERLKKSSHNFTNSNSAKAFFDEKFQNPDMLANLDNKRRKIIETKKSTALSRELGKIMRRRESSGLEDKSVGERQKMKRTTESALQTGLIQRLGFDPTHGKISQVLKSSVSGSEPKNNLLGKKKTVINDLLHYKKEKVILAPSKNEWFKKRSHREEVWQKHFGSKETKETSDGSASDLEII", "length": 571, "molWeight": 65815, "crc64": "D32CFF4A94FD9B2A", "md5": "3986A3F0266A7E6608766F956D673CBA"}}
{"primaryAccession": "P32378", "text": "This is 4-hydroxybenzoate polyprenyltransferase, mitochondrial protein, from Baker's yeast, contains 372 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32378", "organism_name": "Baker's yeast", "protein_name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "length": 372, "firstPublicDate": "1993-10-01", "FUNCTION": "Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group, Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the UbiA prenyltransferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFIWQRKSILLGRSILGSGRVTVAGIIGSSRKRYTSSSSSSSSPSSKESAPVFTSKELEVARKERLDGLGPFVSRLPKKWIPYAELMRLEKPVGTWLLYLPCSWSILMGAMMQGATLSATAGMLGIFGVGALVMRGAGCTINDFLDRKLDQRVIRSVERPIASGRVSPRRALVFLGAQTLVGMGVLSLLPAQCWWLGLASLPIVFTYPLFKRFTYYPQAALSACFNWGALLGFPAMGVMSWPTMIPLYLSSYLWCMTYDTIYAHQDKKFDIKAGIKSTALAWGPRTKSIMKAMSASQIALLAVAGLNSGLLWGPGFIGGLGVFAYRLFSMIKKVDLDNPKNCWKYFNANINTGLYFTYALAVDYILRLFGFL", "length": 372, "molWeight": 41001, "crc64": "4D9738CE248B4AD6", "md5": "F1E55E171C1D87854B9DCADF70E002CE"}}
{"primaryAccession": "P32389", "text": "This is Transcriptional activator of sulfur metabolism MET4 protein, from Baker's yeast, contains 672 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32389", "organism_name": "Baker's yeast", "protein_name": "Transcriptional activator of sulfur metabolism MET4", "length": 672, "firstPublicDate": "1993-10-01", "FUNCTION": "Positive trans-acting factor capable of stimulating the transcription of the MET genes from the methionine biosynthetic pathway, MET4, MET28 and CBF1 are required for full induction of MET25 and MET16 gene transcription, MET4 controls as well the derepression of MET6, Required for the transcription of genes necessary for sulfur amino acid biosynthesis, Involved in the transcription activation of MET28 and MET30, Required for MET3 gene expression via assembly of the MET4-MET28-MET31 and MET4-MET28-MET32 complexes, Involved in response to cadmium and arsenic, Cadmium-activated MET4 also induces glutathione biosynthesis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKQEQSHEGDSYSTEFINLFGKDTATHPSSNNGANNNGMGSTNSLDQFVATASSSSSLVTSSENRRPLIGDVTNRGNTNLYDHAVTPEILLEQLAYVDNFIPSLDNEFSNVDWNVNTTHNNANNNGADTFSSINANPFDLDEQLAIELSAFADDSFIFPDEDKPSNNNNNSNNGNDDHSNHDVLHEDPSTNNRQRNPHFLTQRRNTFLTSQYDQSKSRFSSKNKRNGNNGETNNFGDNMQNNHPFEPNFMGSPSQFPADATNMTSIDHGGFTNVDITSTENNTTGDNGVDALSNLLHRTTHTPNRSSPLSNVTSAQNSSSQQRKHSESKVDSNSDNNSSNKAPNITVPDYSIIPTSVLVTLLPRVNVPNGAYNSLISAGFDNDQIDAIAAIMAYHHQKKIRENNSNNNKNINTNDSQEAPILKNINELLSVLIPPSPAETRGPTTLSTSPSFNEHGVVAEASFLSSILELGIKHPKSNNIHNQRQPSRNDHKISRESDGNNGNDNVHHNNAVIKSSTTRGDEIAKIRSEPTLNASSSDHKENSLKRSHSGDLKNKKVPVDRKYSDNEDDEYDDADLHGFEKKQLIKKELGDDDEDLLIQSKKSHQKKKLKEKELESSIHELTEIAASLQKRIHTLETENKLLKNLVLSSGETEGIKKAESLKKQIFEKVQKE", "length": 672, "molWeight": 74373, "crc64": "D65745E1FA40C09D", "md5": "D3CEBA00B7724F771666DA31BE167165"}}
{"primaryAccession": "P32418", "text": "This is Sodium/calcium exchanger 1 protein, from Human, contains 973 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32418", "organism_name": "Human", "protein_name": "Sodium/calcium exchanger 1", "length": 973, "firstPublicDate": "1993-10-01", "FUNCTION": "Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:1374913, PubMed:11241183, PubMed:1476165), Contributes to Ca(2+) transport during excitation-contraction coupling in muscle (PubMed:1374913, PubMed:11241183, PubMed:1476165), In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum (PubMed:1374913, PubMed:11241183, PubMed:1476165), SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline (PubMed:1374913, PubMed:11241183, PubMed:1476165), Required for normal embryonic heart development and the onset of heart contractions (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2,A,19) family, SLC8 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF", "length": 973, "molWeight": 108547, "crc64": "17DFC1B1F15921D8", "md5": "0F815DF05A8F86F65806EFC9B38CC972"}}
{"primaryAccession": "P32447", "text": "This is Histone chaperone ASF1 protein, from Baker's yeast, contains 279 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32447", "organism_name": "Baker's yeast", "protein_name": "Histone chaperone ASF1", "length": 279, "firstPublicDate": "1993-10-01", "FUNCTION": "Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (PubMed:16936140, PubMed:16678113, PubMed:16407267, PubMed:16039596, PubMed:15891116, PubMed:16303565, PubMed:15766286, PubMed:15542829, PubMed:15175160, PubMed:15452122, PubMed:15071494, PubMed:11856374, PubMed:11404324, PubMed:11331602, PubMed:11172707, PubMed:14680630), Facilitates histone deposition through both replication-dependent and replication-independent chromatin assembly pathways (PubMed:14585955, PubMed:16678113, PubMed:15632066), Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with the HIR complex to promote replication-independent chromatin assembly, which may occur during transcription and DNA repair (PubMed:16501045, PubMed:16582440, PubMed:16141196, PubMed:16143623, PubMed:16020781, PubMed:15821127, PubMed:16303565, PubMed:15542840, PubMed:12093919, PubMed:11756556, PubMed:11404324, PubMed:11731480, PubMed:11731479, PubMed:11412995, PubMed:10591219), May be required for the maintenance of a subset of replication elongation factors, including DNA polymerase epsilon, the RFC complex and PCNA, at stalled replication forks (PubMed:15901673, PubMed:11412995), Also required for RTT109-dependent acetylation of histone H3 on 'Lys-9' and 'Lys-56' (PubMed:17320445, PubMed:17107956, PubMed:17046836, PubMed:16815704, PubMed:16627621, PubMed:15840725, PubMed:21256037), Promotion of RTT109-mediated histone H3 'Lys-56' acetylation is dependent on interactions with histone H3 pre-acetylated on 'Lys-14' (PubMed:31194870)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ASF1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSIVSLLGIKVLNNPAKFTDPYEFEITFECLESLKHDLEWKLTYVGSSRSLDHDQELDSILVGPVPVGVNKFVFSADPPSAELIPASELVSVTVILLSCSYDGREFVRVGYYVNNEYDEEELRENPPAKVQVDHIVRNILAEKPRVTRFNIVWDNENEGDLYPPEQPGVDDEEEEDDEEEDDDEDDEDDEDDDQEDGEGEAEEAAEEEEEEEEKTEDNETNLEEEEEDIENSDGDEEEGEEEVGSVDKNEDGNDKKRRKIEGGSTDIESTPKDAARSTN", "length": 279, "molWeight": 31603, "crc64": "186E76075C0B1644", "md5": "11094D5C1FF330C55591749472E1D7ED"}}
{"primaryAccession": "P32478", "text": "This is Cell wall mannoprotein HSP150 protein, from Baker's yeast, contains 413 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32478", "organism_name": "Baker's yeast", "protein_name": "Cell wall mannoprotein HSP150", "length": 413, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the outer cell wall layer, Required for stability of the cell wall and for optimal growth, Required for resistance against several antifungal and cell wall-perturbing agents and for tolerance to heat shock", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the PIR protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQYKKTLVASALAATTLAAYAPSEPWSTLTPTATYSGGVTDYASTFGIAVQPISTTSSASSAATTASSKAKRAASQIGDGQVQAATTTASVSTKSTAAAVSQIGDGQIQATTKTTAAAVSQIGDGQIQATTKTTSAKTTAAAVSQISDGQIQATTTTLAPKSTAAAVSQIGDGQVQATTTTLAPKSTAAAVSQIGDGQVQATTKTTAAAVSQIGDGQVQATTKTTAAAVSQIGDGQVQATTKTTAAAVSQIGDGQVQATTKTTAAAVSQITDGQVQATTKTTQAASQVSDGQVQATTATSASAAATSTDPVDAVSCKTSGTLEMNLKGGILTDGKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITPDGNLAIGDNDVFYQCLSGTFYNLYDEHIGSQCTPVHLEAIDLIDC", "length": 413, "molWeight": 41059, "crc64": "5EAF10136E25132A", "md5": "187AEEB24D1C6D06268B309658C3D842"}}
{"primaryAccession": "P32480", "text": "This is Protein HIR2 protein, from Baker's yeast, contains 875 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32480", "organism_name": "Baker's yeast", "protein_name": "Protein HIR2", "length": 875, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the HIR complex, which cooperates with ASF1 to promote replication-independent chromatin assembly, The HIR complex is also required for the periodic repression of three of the four histone gene loci during the cell cycle as well as for autogenous regulation of the HTA1-HTB1 locus by H2A and H2B, DNA-binding by the HIR complex may repress transcription by inhibiting nucleosome remodeling by the SWI/SNF complex, The HIR complex may also be required for transcriptional silencing of centromeric, telomeric and mating-type loci in the absence of CAF-1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WD repeat HIR1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRLLKYPLDIHNEQVNALAALGPYIILAGSGGHVMAWRQQQLVDTAFDRVMIKDLKPEVSFQVDQDTTGDIFFITGDLETLYIGSEHRLWGYSGWLCRDTNNINSVEKMNSKLLFECKSPSTITDVKYDINLGILFVLLSNENKILLFRHKTFDKLSEITIDKASKPITGIIDPTGQTFTVMTSDRSILVYQINKTGTHKLINKLTQHVQMYPLHYRISMSPQADILPVINSVKGVPNNATSCTALLDRNNNYKVTKTLVTPSSNGCRVLVYSPAFYEKPNLKKGTSTRYNLIATSGSTDGTILVWNTKRMKPLFNALQVSSTAINDMSWSQDGFTLFAISNDATLYTFAFQEKDLGVALPQTEIKSLQEVNKKLPKLEEPLAEQIPKSFPENIKLEESASAAPIPNDIGRSAVGKKPTKKKTANNQTNGIKTIQSTSMEFNTPSYTVPRDLKRKPKEATPSNIAPGSKKQKKELQPIDFLDTGLLLPNTSFSRIRLATPKIRSTFKYSPINNPNLILDVKNGSGNEQRPTIVKLTSKVLDQDQVLFQDFIPKLITICTAGDTFWSFCSEDGSIYIYSDSGRKLMAPLVLGVSISFLEACGTYLLCLTSIGELYCWNIEQKKLAFPTNTIYPLLNPSLRYSDDILTRAENITLCSITKKGVPLVTLSNGDGYLFDKNMETWLLVSDGWWAYGSQYWDTTNTTGLSSSKANTDSFNGSESNINEIVSDIKNDNQSIINFLECKTNDELNRKGRIKNLQRFARTILMKEGFENMEEIVTLSHLENKILISIRLEEPEEFSKLMMVYCIRLSELGYMDRLNDVFQWLYDDLPISGTGSAFADKDFKRNLLKKILIACGDIRQVQRVTTRYAKEMNIIS", "length": 875, "molWeight": 98445, "crc64": "C77D677BF424680D", "md5": "88458C80FB8DD1F5DA51B0B3DEE61010"}}
{"primaryAccession": "P32497", "text": "This is Eukaryotic translation initiation factor 3 subunit C protein, from Baker's yeast, contains 812 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32497", "organism_name": "Baker's yeast", "protein_name": "Eukaryotic translation initiation factor 3 subunit C", "length": 812, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome, The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eIF-3 subunit C family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSRFFSSNYEYDVASSSSEEDLLSSSEEDLLSSSSSESELDQESDDSFFNESESESEADVDSDDSDAKPYGPDWFKKSEFRKQGGGSNKFLKSSNYDSSDEESDEEDGKKVVKSAKEKLLDEMQDVYNKISQAENSDDWLTISNEFDLISRLLVRAQQQNWGTPNIFIKVVAQVEDAVNNTQQADLKNKAVARAYNTTKQRVKKVSRENEDSMAKFRNDPESFDKEPTADLDISANGFTISSSQGNDQAVQEDFFTRLQTIIDSRGKKTVNQQSLISTLEELLTVAEKPYEFIMAYLTLIPSRFDASANLSYQPIDQWKSSFNDISKLLSILDQTIDTYQVNEFADPIDFIEDEPKEDSDGVKRILGSIFSFVERLDDEFMKSLLNIDPHSSDYLIRLRDEQSIYNLILRTQLYFEATLKDEHDLERALTRPFVKRLDHIYYKSENLIKIMETAAWNIIPAQFKSKFTSKDQLDSADYVDNLIDGLSTILSKQNNIAVQKRAILYNIYYTALNKDFQTAKDMLLTSQVQTNINQFDSSLQILFNRVVVQLGLSAFKLCLIEECHQILNDLLSSSHLREILGQQSLHRISLNSSNNASADERARQCLPYHQHINLDLIDVVFLTCSLLIEIPRMTAFYSGIKVKRIPYSPKSIRRSLEHYDKLSFQGPPETLRDYVLFAAKSMQKGNWRDSVKYLREIKSWALLPNMETVLNSLTERVQVESLKTYFFSFKRFYSSFSVAKLAELFDLPENKVVEVLQSVIAELEIPAKLNDEKTIFVVEKGDEITKLEEAMVKLNKEYKIAKERLNPPSNRR", "length": 812, "molWeight": 93204, "crc64": "EE05097C44C45A4C", "md5": "FB326B107DB32EA838C173BBC4479025"}}
{"primaryAccession": "P32527", "text": "This is Zuotin protein, from Baker's yeast, contains 433 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32527", "organism_name": "Baker's yeast", "protein_name": "Zuotin", "length": 433, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state, RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain, ZUO1 can act as a J-protein for SSB1/SSB2 only when associated with SSZ1", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFSLPTLTSDITVEVNSSATKTPFVRRPVEPVGKFFLQHAQRTLRNHTWSEFERIEAEKNVKTVDESNVDPDELLFDTELADEDLLTHDARDWKTADLYAAMGLSKLRFRATESQIIKAHRKQVVKYHPDKQSAAGGSLDQDGFFKIIQKAFETLTDSNKRAQYDSCDFVADVPPPKKGTDYDFYEAWGPVFEAEARFSKKTPIPSLGNKDSSKKEVEQFYAFWHRFDSWRTFEFLDEDVPDDSSNRDHKRYIERKNKAARDKKKTADNARLVKLVERAVSEDPRIKMFKEEEKKEKERRKWEREAGARAEAEAKAKAEAEAKAKAESEAKANASAKADKKKAKEAAKAAKKKNKRAIRNSAKEADYFGDADKATTIDEQVGLIVDSLNDEELVSTADKIKANAAGAKEVLKESAKTIVDSGKLPSSLLSYFV", "length": 433, "molWeight": 49020, "crc64": "0AA76BC11D3C7DAB", "md5": "46342A66131FD1E0EC9C125A9D3C4527"}}
{"primaryAccession": "P32569", "text": "This is Mediator of RNA polymerase II transcription subunit 17 protein, from Baker's yeast, contains 687 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32569", "organism_name": "Baker's yeast", "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "length": 687, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes, Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors, The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II, The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Mediator complex subunit 17 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTTEDPDSNHLSSETGIKLALDPNLITLALSSNPNSSLHSPTSDEPVPESAGKADTSIRLEGDELENKTKKDNDKNLKFLKNKDSLVSNPHEIYGSMPLEQLIPIILRQRGPGFKFVDLNEKELQNEIKQLGSDSSDGHNSEKKDTDGADENVQIGEDFMEVDYEDKDNPVDSRNETDHKTNENGETDDNIETVMTQEQFVKRRRDMLEHINLAMNESSLALEFVSLLLSSVKESTGMSSMSPFLRKVVKPSSLNSDKIPYVAPTKKEYIELDILNKGWKLQSLNESKDLLRASFNKLSSILQNEHDYWNKIMQSISNKDVIFKIRDRTSGQKLLAIKYGYEDSGSTYKHDRGIANIRNNIESQNLDLIPHSSSVFKGTDFVHSVKKFLRVRIFTKIESEDDYILSGESVMDRDSESEEAETKDIRKQIQLLKKIIFEKELMYQIKKECALLISYGVSIENENKVIIELPNEKFEIELLSLDDDSIVNHEQDLPKINDKRANLMLVMLRLLLVVIFKKTLRSRISSPHGLINLNVDDDILIIRPILGKVRFANYKLLLKKIIKDYVLDIVPGSSITETEVEREQPQENKNIDDENITKLNKEIRAFDKLLNIPRRELKINLPLTEHKSPNLSLMLESPNYCNALIHIKFSAGTEANAVSFDTTFSDFKEVEDFLHFIVAEYIQQKKV", "length": 687, "molWeight": 78476, "crc64": "D25B2993A1BADFD6", "md5": "FC5D31C46D79D8835EBB9EBE407F75D8"}}
{"primaryAccession": "P32621", "text": "This is Guanosine-diphosphatase protein, from Baker's yeast, contains 518 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32621", "organism_name": "Baker's yeast", "protein_name": "Guanosine-diphosphatase", "length": 518, "firstPublicDate": "1993-10-01", "FUNCTION": "After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GDA1/CD39 NTPase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPIFRNYRFAIGAFAVIMLILLIKTSSIGPPSIARTVTPNASIPKTPEDISILPVNDEPGYLQDSKTEQNYPELADAVKSQTSQTCSEEHKYVIMIDAGSTGSRVHIYKFDVCTSPPTLLDEKFDMLEPGLSSFDTDSVGAANSLDPLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDGVSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVFEPTFPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNTKTHQLSSPCLPPKVNATNEKVTLESKETYTIDFIGPDEPSGAQCRFLTDEILNKDAQCQSPPCSFNGVHQPSLVRTFKESNDIYIFSYFYDRTRPLGMPLSFTLNELNDLARIVCKGEETWNSVFSGIAGSLDELESDSHFCLDLSFQVSLLHTGYDIPLQRELRTGKKIANKEIGWCLGASLPLLKADNWKCKIQSA", "length": 518, "molWeight": 56822, "crc64": "9A61182D5ED22ADF", "md5": "AF9DC874BD9B190A94F5ACBE797F6B9A"}}
{"primaryAccession": "P32793", "text": "This is Protein YSC84 protein, from Baker's yeast, contains 468 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32793", "organism_name": "Baker's yeast", "protein_name": "Protein YSC84", "length": 468, "firstPublicDate": "1993-10-01", "FUNCTION": "Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking, together with LSB5", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the SH3YL1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGINNPIPRSLKSETKKAAKVLRSFVKPNQVFGADQVIPPYVLKRAKGLAIITVLKAGFLFSGRAGSGVIVARLKDGTWSAPSAIAMAGAGAGGMVGVELTDFVFILNSEEAVRSFSEFGTITLGGNVSVSAGPLGRSAEAAASASTGGVSAVFAYSKSKGLFAGVSVEGSAILERREANRKFYGDNCTSKMILSGRVKVPPAADPLLRILESRAFNFTRHDHDDNASGDDFYDDGQYSDNTSHYYDDIPDSFDSTDESSTRPNTRSSRRRGMSLGSRSRYDDDYDDDGYGRGRGYGDFDSEDEDYDYGRSPNRNSSRNRGPQIDRGTKPRANTRWEDDLYDRDTEYSRPNHSGRDYDNTRGNRRGYGRERGYSLGHGPTHPSNMSNVDDLSHKMSKTGLGNESTATNSATPTAVALYNFAGEQPGDLAFKKGDVITILKKSDSQNDWWTGRTNGKEGIFPANYVRVS", "length": 468, "molWeight": 50902, "crc64": "DE42E8ECF5B83C92", "md5": "8AEAFB6868BA64F8916E60789A852913"}}
{"primaryAccession": "P32860", "text": "This is NifU-like protein, mitochondrial protein, from Baker's yeast, contains 256 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32860", "organism_name": "Baker's yeast", "protein_name": "NifU-like protein, mitochondrial", "length": 256, "firstPublicDate": "1993-10-01", "FUNCTION": "Involved in iron homeostasis within the mitochondrion where it is involved in the assembly of iron-sulfur proteins (PubMed:10468587, PubMed:27532773), Together with BOL3, required during the last step of iron-sulfur protein assembly when the iron-sulfur cluster is inserted into the target protein (PubMed:27532773), Required for protecting iron sulfur clusters from oxidative damage (PubMed:27532773)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the NifU family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFKSVAKLGKSPIFYLNSQRLIHIKTLTTPNENALKFLSTDGEMLQTRGSKSIVIKNTDENLINHSKLAQQIFLQCPGVESLMIGDDFLTINKDRMVHWNSIKPEIIDLLTKQLAYGEDVISKEFHAVQEEEGEGGYKINMPKFELTEEDEEVSELIEELIDTRIRPAILEDGGDIDYRGWDPKTGTVYLRLQGACTSCSSSEVTLKYGIESMLKHYVDEVKEVIQIMDPEQEIALKEFDKLEKKLESSKNTSHEK", "length": 256, "molWeight": 29174, "crc64": "4EF11EFD9C438BB5", "md5": "9CC6254740584992E7B8DDB9D04A128A"}}
{"primaryAccession": "P32905", "text": "This is Small ribosomal subunit protein uS2A protein, from Baker's yeast, contains 252 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32905", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein uS2A", "length": 252, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102), uS2 is required for the assembly and/or stability of the 40S ribosomal subunit, Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (PubMed:9973221, PubMed:14627813)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the universal ribosomal protein uS2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTFGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRSDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRDPEEVEQQVAEEATTEEAGEEEAKEEVTEEQAEATEWAEENADNVEW", "length": 252, "molWeight": 28024, "crc64": "D6F263456282C771", "md5": "F77527328E7CBB17D62091E692331EB7"}}
{"primaryAccession": "P32916", "text": "This is Signal recognition particle receptor subunit alpha homolog protein, from Baker's yeast, contains 621 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32916", "organism_name": "Baker's yeast", "protein_name": "Signal recognition particle receptor subunit alpha homolog", "length": 621, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the SRP (signal recognition particle) receptor (SR), Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system, GTP hydrolysis may enhance the fidelity of and provide unidirectionality to the targeting reaction, It is important but not essential for cell growth, May be directly involved in mitochondrial protein import", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the GTP-binding SRP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFDQLAVFTPQGQVLYQYNCLGKKFSEIQINSFISQLITSPVTRKESVANANTDGFDFNLLTINSEHKNSPSFNALFYLNKQPELYFVVTFAEQTLELNQETQQTLALVLKLWNSLHLSESILKNRQGQNEKNKHNYVDILQGIEDDLKKFEQYFRIKYEESIKQDHINPDNFTKNGSVPQSHNKNTKKKLRDTKGKKQSTGNVGSGRKWGRDGGMLDEMNHEDAAKLDFSSSNSHNSSQVALDSTINKDSFGDRTEGGDFLIKEIDDLLSSHKDEITSGNEAKNSGYVSTAFGFLQKHVLGNKTINESDLKSVLEKLTQQLITKNVAPEAADYLTQQVSHDLVGSKTANWTSVENTARESLTKALTQILTPGVSVDLLREIQSKRSKKDEEGKCDPYVFSIVGVNGVGKSTNLSKLAFWLLQNNFKVLIVACDTFRSGAVEQLRVHVENLAQLMDDSHVRGSKNKRGKTGNDYVELFEAGYGGSDLVTKIAKQAIKYSRDQNFDIVLMDTAGRRHNDPTLMSPLKSFADQAKPDKIIMVGEALVGTDSVQQAKNFNDAFGKGRNLDFFIISKCDTVGEMLGTMVNMVYATGIPILFVGVGQTYTDLRTLSVKWAVNTLMS", "length": 621, "molWeight": 69278, "crc64": "032400E5B3310C91", "md5": "A0C989318EFB067347D1CA4AE3F82A78"}}
{"primaryAccession": "P33203", "text": "This is Pre-mRNA-processing protein PRP40 protein, from Baker's yeast, contains 583 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P33203", "organism_name": "Baker's yeast", "protein_name": "Pre-mRNA-processing protein PRP40", "length": 583, "firstPublicDate": "1994-02-01", "FUNCTION": "Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing, This protein is associated with snRNP U1, Two commitment complexes, CC1 and CC2, have been defined in yeast, CC1 is a basal complex dependent only on the 5' splice site, CC2 is a complex of lower mobility and is dependent on a branchpoint as well as a 5' splice site region, This protein is involved in CC2 formation where it binds to the branchpoint binding protein MSL5, bridging the U1 snRNP-associated 5' splice site and the MSL5-associated branch point 3' intron splice site", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the PRPF40 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSIWKEAKDASGRIYYYNTLTKKSTWEKPKELISQEELLLRENGWKAAKTADGKVYYYNPTTRETSWTIPAFEKKVEPIAEQKHDTVSHAQVNGNRIALTAGEKQEPGRTINEEESQYANNSKLLNVRRRTKEEAEKEFITMLKENQVDSTWSFSRIISELGTRDPRYWMVDDDPLWKKEMFEKYLSNRSADQLLKEHNETSKFKEAFQKMLQNNSHIKYYTRWPTAKRLIADEPIYKHSVVNEKTKRQTFQDYIDTLIDTQKESKKKLKTQALKELREYLNGIITTSSSETFITWQQLLNHYVFDKSKRYMANRHFKVLTHEDVLNEYLKIVNTIENDLQNKLNELRLRNYTRDRIARDNFKSLLREVPIKIKANTRWSDIYPHIKSDPRFLHMLGRNGSSCLDLFLDFVDEQRMYIFAQRSIAQQTLIDQNFEWNDADSDEITKQNIEKVLENDRKFDKVDKEDISLIVDGLIKQRNEKIQQKLQNERRILEQKKHYFWLLLQRTYTKTGKPKPSTWDLASKELGESLEYKALGDEDNIRRQIFEDFKPESSAPTAESATANLTLTASKKRHLTPAVELDY", "length": 583, "molWeight": 69065, "crc64": "BA1C1C91D532524C", "md5": "03F8D696F6B508AA5966B3DEEE7003FC"}}
{"primaryAccession": "P33313", "text": "This is Hsp70/Hsp90 co-chaperone CNS1 protein, from Baker's yeast, contains 385 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P33313", "organism_name": "Baker's yeast", "protein_name": "Hsp70/Hsp90 co-chaperone CNS1", "length": 385, "firstPublicDate": "1994-02-01", "FUNCTION": "Co-chaperone that binds to the molecular chaperones Hsp90 (HSC82 and HSP82) and Hsp70 (SSA1), Stimulates SSA1 ATPase activity, but not Hsp90 ATPase activity, Involved in only a subset of Hsp90 functions", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TTC4 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSVNANGGYTKPQKYVPGPGDPELPPQLSEFKDKTSDEILKEMNRMPFFMTKLDETDGAGGENVELEALKALAYEGEPHEIAENFKKQGNELYKAKRFKDARELYSKGLAVECEDKSINESLYANRAACELELKNYRRCIEDCSKALTINPKNVKCYYRTSKAFFQLNKLEEAKSAATFANQRIDPENKSILNMLSVIDRKEQELKAKEEKQQREAQERENKKIMLESAMTLRNITNIKTHSPVELLNEGKIRLEDPMDFESQLIYPALIMYPTQDEFDFVGEVSELTTVQELVDLVLEGPQERFKKEGKENFTPKKVLVFMETKAGGLIKAGKKLTFHDILKKESPDVPLFDNALKIYIVPKVESEGWISKWDKQKALERRSV", "length": 385, "molWeight": 44112, "crc64": "742F8254DFDB02A6", "md5": "41EACD7B9DF317336BC12A7646858E94"}}
{"primaryAccession": "P33442", "text": "This is Small ribosomal subunit protein eS1A protein, from Baker's yeast, contains 255 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P33442", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS1A", "length": 255, "firstPublicDate": "1994-02-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAVGKNKRLSKGKKGQKKRVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVCLADLQGSEDHSFRKIKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGEEKGKKVTGFKDEVLETV", "length": 255, "molWeight": 28743, "crc64": "2629D022EDBDE885", "md5": "98DD328D009A851D07267BC92E86117F"}}
{"primaryAccession": "P33891", "text": "This is Protein transport protein TIP20 protein, from Baker's yeast, contains 701 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P33891", "organism_name": "Baker's yeast", "protein_name": "Protein transport protein TIP20", "length": 701, "firstPublicDate": "1994-02-01", "FUNCTION": "Required for protein transport between the Golgi and the endoplasmic reticulum, May contribute to tethering of coatomer-coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNGIDDLLNINDRIKQVQNERNELASKLQNLKQSLASNDTEVALSEVIAQDIIEVGASVEGLEQLRAKYGDLQILNKLEKVAVQQTQMQAGVDKLDSFERQLDELAEQPPDQFTLDDVKALHSKLTSVFATVPQINNIDSQYAAYNKLKSKVTGKYNDVIIQRLATNWSNTFDQKLLEAQWDTQKFASTSVGLVKCLRENSTKLYQLSLLYLPLEEETQNGDSERPLSRSNNNQEPVLWNFKSLANNFNVRFTYHFHATSSSSKIETYFQFLNDYLAENLYKCINIFHDDCNGLTKPVIHEQFINYVLQPIRDKVRSTLFQNDLKTLIVLISQILATDKNLLNSFHYHGLGLVSLISDEVWEKWINYEVEMANRQFINITKNPEDFPKSSQNFVKLINKIYDYLEPFYDLDFDLLVRYKLMTCSLIFMNLTSSYLDYILTVDSLNETRTKEQELYQTMAKLQHVNFVYRKIKSLSSNFIFIQLTDIVNSTESKKYNSLFQNVENDYEKAMSTDMQNSIVHRIQKLLKETLRNYFKISTWSTLEMSVDENIGPSSVPSAELVNSINVLRRLINKLDSMDIPLAISLKVKNELLNVIVNYFTESILKLNKFNQNGLNQFLHDFKSLSSILSLPSHATNYKCMSLHELVKILKLKYDPNNQQFLNPEYIKTGNFTSLKEAYSIKYLKDTKIQDALYRIIYGNIL", "length": 701, "molWeight": 81167, "crc64": "3E561DD4C0B9C176", "md5": "EC204203CD1007AAA8ED276804EC8584"}}
{"primaryAccession": "P34611", "text": "This is B-box type zinc finger protein ncl-1 protein, from Caenorhabditis elegans, contains 851 amino acids, has 1 B box-type 1; atypical Zinc finger, has 1 B box-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [127, 174], "description": "B box-type 1; atypical", "keyword_description": "Zinc finger", "textural_description": "B box-type 1; atypical Zinc finger"}, {"location": [218, 261], "description": "B box-type", "keyword_description": "Zinc finger", "textural_description": "B box-type Zinc finger"}], "meta_data": {"primaryAccession": "P34611", "organism_name": "Caenorhabditis elegans", "protein_name": "B-box type zinc finger protein ncl-1", "length": 851, "firstPublicDate": "1994-02-01", "FUNCTION": "Translational repressor that inhibits protein synthesis (PubMed:9508766, PubMed:26492166), Represses the translation of mRNAs such as fib-1, probably by being recruited by RNA-binding protein nos-2 and the Pumilio proteins puf-5, puf-8 and puf-9 to the consensus core PUF binding motif in the 3'-UTR of fib-1 mRNA (PubMed:26492166), Negatively regulates ribosomal RNA (rRNA) synthesis, ribosomal protein synthesis and nucleolus size (PubMed:9508766, PubMed:8582642, PubMed:22768349, PubMed:26492166, PubMed:28853436), Its role in the negative regulation of nucleolus size is most likely through its negative regulation of the translation of proteins such as the rRNA 2'-O-methyltransferase fib-1, and dao-5 (PubMed:26492166, PubMed:28853436), Might act directly as a transcription factor to inhibit RNA polymerase I (rRNA) and III (5S RNA) transcription (PubMed:9508766), Plays a role in embryonic development, and in particular, is involved in regulating the localization of proteins, such as par-2, that are required for embryonic cell polarity (PubMed:18652816), Plays a role in the regulation of lifespan, and the response to nutrient availability (PubMed:28853436)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"B box-type 1; atypical Zinc finger": 1, "B box-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "METQLSVQLGLDSLLTDFGLESVMNKQQQLFANMGLSDIGAPTPSTAIPVPNAHLHPSMVAGSDPSNPVVGFGFGSPSSTTSSSPPLSNSPTIEQQQHAQLTAMMQGIMSNNNVAVSNGSGVQVASVPAVHCSGCKSNETATSFCQDCNANLCDNCTMAHKFMHCFADHRVVSLTTPGTGSSSSSTSSSSSASSTSSHQVPSLGGKQSPDSMMLGSGKRSVLCLQHRASELVFFCVSCNLAICRDCTVSDHPSGTHQYELIADVADKQMLKMEQLIADARSKHADMLDMFKQVDNKQQVLTASLHNAHAQLEETVSNLINVIQDQKKTLAKDIDNAFAAKQIQLTMVDKRIQSMADKLSQTIEFSRRLMSFASPAEVMVFKQLLDTRLQLFLGFNPDTSGVLMTPCEIEYLGAAGLFNNSASTVSQLLGSVHGGSPINNAPAANDFLMPQAGLAPIGRAQSRIIPIEQNQLARSPPHHIAGSLPMNAYSDSNLLRPNKDFGGSSQSLGPFNPLGASVPGAAADPFSSQYDKWSLGVEPSVGGLLEGGNVDEEKFQTLFPPSRSQIKRQKMIYHCKFGEFGVMEGQFTEPSGVAVNGQGDIVVADTNNHRIQVFDKEGRFKFQFGECGKRDGQLLYPNRVAVNRTTGDFVVTERSPTHQIQVYNQYGQFLRKFGANILQHPRGVCVDSKGRIIVVECKVMRVIIFDMFGNILQKFSCSRYLEFPNGVCTNDKNEILISDNRAHCIKVFSYEGQYLRQIGGEGVTNYPIGVGINSLGEVVVADNHNNFNLTVFSQDGTMIGALESRVKHAQCFDVALVDDGSVVLASKDYRLYLYRFLPATSGQSTSSASSQI", "length": 851, "molWeight": 91955, "crc64": "166FDC4623AE494C", "md5": "90C0A08CC7ED577B76BFA64FD0C77627"}}
{"primaryAccession": "P34982", "text": "This is Olfactory receptor 1D2 protein, from Human, contains 312 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P34982", "organism_name": "Human", "protein_name": "Olfactory receptor 1D2", "length": 312, "firstPublicDate": "1994-02-01", "FUNCTION": "Odorant receptor which may be involved in sperm chemotaxis, Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro, May also function in olfactory reception", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDGGNQSEGSEFLLLGMSESPEQQRILFWMFLSMYLVTVVGNVLIILAISSDSRLHTPVYFFLANLSFTDLFFVTNTIPKMLVNLQSHNKAISYAGCLTQLYFLVSLVALDNLILAVMAYDRYVAICCPLHYTTAMSPKLCILLLSLCWVLSVLYGLIHTLLMTRVTFCGSRKIHYIFCEMYVLLRMACSNIQINHTVLIATGCFIFLIPFGFVIISYVLIIRAILRIPSVSKKYKAFSTCASHLGAVSLFYGTLCMVYLKPLHTYSVKDSVATVMYAVVTPMMNPFIYSLRNKDMHGALGRLLDKHFKRLT", "length": 312, "molWeight": 35240, "crc64": "71B05367C0AA135B", "md5": "06D638825141C954E7564921AE9F1D84"}}
{"primaryAccession": "P35064", "text": "This is Histone H2AX protein, from Tetrahymena thermophila (strain SB210), contains 138 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35064", "organism_name": "Tetrahymena thermophila (strain SB210)", "protein_name": "Histone H2AX", "length": 138, "firstPublicDate": "1994-02-01", "FUNCTION": "Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSTTGKGGKAKGKTASSKQVSRSARAGLQFPVGRISRFLKHGRYSERVGTGAPVYLAAVLEYLAAEVLELAGNAAKDNKKTRIVPRHILLAIRNDEELNKLMANTTIADGGVLPNINPMLLPSKSKKTESRGQASQDL", "length": 138, "molWeight": 14771, "crc64": "299D1442BC0658F0", "md5": "A423F3C1758C8673EFA648940C72D9E8"}}
{"primaryAccession": "P35523", "text": "This is Chloride channel protein 1 protein, from Human, contains 988 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35523", "organism_name": "Human", "protein_name": "Chloride channel protein 1", "length": 988, "firstPublicDate": "1994-06-01", "FUNCTION": "Voltage-gated chloride channel (PubMed:8112288, PubMed:9122265, PubMed:12456816), Plays an important role in membrane repolarization in skeletal muscle cells after muscle contraction, The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (Probable), The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the chloride channel (TC 2,A,49) family, ClC-1/CLCN1 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLSGKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRARPTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESPGLEEELADILQGPSLRSTDEEDEDELIL", "length": 988, "molWeight": 108626, "crc64": "CA838BCD2AF3CA68", "md5": "436F420180FA10C3290572B32253F329"}}
{"primaryAccession": "P35525", "text": "This is Chloride channel protein 2 protein, from Rat, contains 907 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35525", "organism_name": "Rat", "protein_name": "Chloride channel protein 2", "length": 907, "firstPublicDate": "1994-06-01", "FUNCTION": "Voltage-gated chloride channel (PubMed:1311421, PubMed:12163466), Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport (PubMed:1311421), Involved in the regulation of aldosterone production, The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the chloride channel (TC 2,A,49) family, ClC-2/CLCN2 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAATAAAATVAGEGMEPRALQYEQTLMYGRYTQELGAFAKEEAARIRLGGPEPWKGSPSARATPELLEYGQSRCARCRICSVRCHKFLVSRVGEDWIFLVLLGLLMALVSWAMDYAIAVCLQAQQWMSRGLNTNILLQYLAWVTYPVVLITFSAGFTQILAPQAVGSGIPEMKTILRGVVLKEYLTLKTFVAKVIGLTCALGSGMPLGKEGPFVHIASMCAALLSKFLSLFGGIYENESRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMKKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLFDNRTWVRQGLVEDLGAPSTSQAWSPPRANVFLTLVIFILMKFWMSALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPGGYAVVGAAALAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLPELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGSIERSQVVALLGAQLSPARRRQHMQKLRKAQMSPPSDQESPPSSETSIRFQVNTEDSGFPGAHGQTHKPLKPALKRGPSNATSLQEGTTGNMESAGIALRSLFCGSPPLESTTSELEKSESCDKRKLKRVRISLASDSDLEGKMSPEEILEWEEQQLDEPVNFSDCKIDPAPFQLVERTSLHKTHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSDTETTEVHALWGPRSRHGLPREGTPSDSDDKCQ", "length": 907, "molWeight": 99328, "crc64": "6192EEB2EE0D6528", "md5": "0F10FED0E2688409B94EE2A593FC5B1C"}}
{"primaryAccession": "P35997", "text": "This is Small ribosomal subunit protein eS27A protein, from Baker's yeast, contains 82 amino acids, has 1 C4-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [37, 59], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "P35997", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS27A", "length": 82, "firstPublicDate": "1994-06-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS27 family", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTILCTPTGGKAKLSEGTSFRRK", "length": 82, "molWeight": 8879, "crc64": "FCA80130CFCEC91E", "md5": "2CA667BB3FE937C92797CDE042881DC8"}}
{"primaryAccession": "P36041", "text": "This is Protein EAP1 protein, from Baker's yeast, contains 632 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36041", "organism_name": "Baker's yeast", "protein_name": "Protein EAP1", "length": 632, "firstPublicDate": "1994-06-01", "FUNCTION": "Can regulate translation through binding to eIF4E, Competes with eIF4G and p20 for binding to eIF4E in vivo and inhibits cap-dependent translation in vitro, Plays a role in cell growth and is implicated in the TOR signaling cascade, Functions independently of eIF4E to maintain genetic stability and to attenuate GCN4 translation upon TOR inactivation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MELNDPSIISSSQFSGELSDSDTAAATHKSQQAISNLFQKLAKKGREEKPIGSVESSTDSSNISVATSGNNKESNKKKNKKTAMLNFSSLTDPITNYKPMDLQYKTYAYSMNELYHLKPSLASASYEEDPLISELVRSLPKRKFWRLRMGPPDQKHANNHHFNGNNGGGSWKAGYKNGKNDERRMSRTKNMQGGKRRSQQDDEEKKIDQEMLEMDKNLQLGGDVGHSIADFEDWKAKMKELELKKLSKSKGISNSTAIAPRESASHETPTDLRPVIPRGPSSITDFLNLKRQDKKEESSQQTPGIPVGQPSLSKTSIEQVNELETNSDLGKSSSSRFSSFFNKSATSLPSLDNNNQVPSSNVSVVNNDGNSTPHQSGSRLMSFFKESRSSTPNAESQLLSASDKDNGKMQTLPQFQQQPQQMQPMAFTQHPPNNNAFFNGLLNKGKSETSTPPPPPPGLIAHQGPQFPVMGVPPNFPQRMMPPPPGLVQFQKDSKDVNKKEDRQLRQNKNPNGTRNSKGKQEETATPDLPQQQYMPPPPPPGFFPMHPNFPNGPMPPLPQGFPIPPNGMLPVTGQQPQPPYPNMMLQGNFPPNFQQGFGSNSPMPIPSIINANGKNVTNQLPPGLNSKKNIK", "length": 632, "molWeight": 69762, "crc64": "775F73F57BB0EF2B", "md5": "A016E46D8E0DA50BF4E95E67AD0092A8"}}
{"primaryAccession": "P36046", "text": "This is Mitochondrial intermembrane space import and assembly protein 40 protein, from Baker's yeast, contains 403 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36046", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "length": 403, "firstPublicDate": "1994-06-01", "FUNCTION": "Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS), Forms a redox cycle with ERV1 that involves a disulfide relay system, Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria, The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS, Reduced MIA40 is reoxidized by FAD-linked sulfhydryl oxidase ERV1", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403, "molWeight": 44536, "crc64": "5904E8D0213D6EFA", "md5": "AB50DD976A7A12D058818B2453C2FC57"}}
{"primaryAccession": "P36156", "text": "This is Glutathione S-transferase omega-like 2 protein, from Baker's yeast, contains 370 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36156", "organism_name": "Baker's yeast", "protein_name": "Glutathione S-transferase omega-like 2", "length": 370, "firstPublicDate": "1994-06-01", "FUNCTION": "Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB), May be involved in cell wall organization and biogenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the GST superfamily, Omega family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSKQWASGTNGAFKRQVSSFRETISKQHPIYKPAKGRYWLYVSLACPWAHRTLITRALKGLTSVIGCSVVHWHLDEKGWRFLDMEKQLEDSEDFLEHWHDVAGGIRTAKEDSSKSFAEIKNDSQRFMVDATNEPHYGYKRISDLYYKSDPQYSARFTVPVLWDLETQTIVNNESSEIIRILNSSAFDEFVDDDHKKTDLVPAQLKTQIDDFNSWVYDSINNGVYKTGFAEKAEVYESEVNNVFEHLDKVEKILSDKYSKLKAKYGEEDRQKILGEFFTVGDQLTEADIRLYTTVIRFDPVYVQHFKCNFTSIRAGYPFIHLWVRNLYWNYDAFRYTTDFDHIKLHYTRSHTRINPLGITPLGPKPDIRPL", "length": 370, "molWeight": 43274, "crc64": "2ED6659ADD4CA6ED", "md5": "A0DFD3B5D05C39A38D37F81A0A4D1DBD"}}
{"primaryAccession": "P36626", "text": "This is Meiotic recombination protein rec8 protein, from Fission yeast, contains 561 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36626", "organism_name": "Fission yeast", "protein_name": "Meiotic recombination protein rec8", "length": 561, "firstPublicDate": "1994-06-01", "FUNCTION": "Involved primarily in the early steps of meiotic recombination, Required to ensure reductional chromosome segregation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the rad21 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFYNQDVLTKEKGGMGVIWLAATLGSKHSLRKLHKKDIMSVDIDEACDFVAFSPEPLALRLSSNLMIGVTRVWAHQYSFFHSQVSTLHLRVRKELDHFTSKPFKNIDIQNEQTNPKQLLLAEDPAFIPEVSLYDAFNLPSVDLHVDMSSFTQPKENPNISVLETLPDSTSYLINTSQNYSLRNNVSSFVYEDSRAFSTEEPLDFEFDENGDIQELTKGTINSDPSLQAASQHSNLGSVQREYNSEEQESRIHMFEIDEDVLPLPVPLQSVMDSEHNENEPRALKRRKVQKLLEPDENIELSTRTLSQWRKNYVERMIALEATKYVRRRGASSAKKKELNKFFDWESFHPLLKPWIEKLKPSNNTPSEIDDVLRNIDTSEVEVGRDVQGELGLNIPWNTSSRSNSAINSKSHSQTGSEHSTPLLDTKYRKRLPHSPSMPSRVEFLPALESSQFHETLNSELSLQLSDDFVLYKNTQEENAHLMLSMEKECANFYEYAKTAIYENNGRITFSSLLPNDLKRPVVAQAFSHLLSLATKSAFLVKQDKPYSEISVSLNLKSTDAI", "length": 561, "molWeight": 64011, "crc64": "E6B9B3A02143D50A", "md5": "BE1A355DEFAEC341E0AEC98A308164DD"}}
{"primaryAccession": "P37173", "text": "This is TGF-beta receptor type-2 protein, from Human, contains 567 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P37173", "organism_name": "Human", "protein_name": "TGF-beta receptor type-2", "length": 567, "firstPublicDate": "1994-10-01", "FUNCTION": "Binds TGFB1, TGFB2 and TGFB3 in the picomolar affinity range without the participation of additional receptors, Blocks activation of SMAD2 and SMAD3 by TGFB1", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSVNNDMIVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLSSTWETGKTRKLMEFSEHCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSELEHLDRLSGRSCSEEKIPEDGSLNTTK", "length": 567, "molWeight": 64568, "crc64": "C541DA751FFBDBEB", "md5": "5F3C51957684D959AEF27FE1997C2728"}}
{"primaryAccession": "P37254", "text": "This is Aminodeoxychorismate synthase protein, from Baker's yeast, contains 787 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P37254", "organism_name": "Baker's yeast", "protein_name": "Aminodeoxychorismate synthase", "length": 787, "firstPublicDate": "1994-10-01", "FUNCTION": "Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine, Required for the synthesis of 4-aminobenzoate (PABA), an important component in tetrahydrofolate biosynthesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "In the C-terminal section; belongs to the anthranilate synthase component I family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLSDTIDTKQQQQQLHVLFIDSYDSFTYNVVRLIEQQTDISPGVNAVHVTTVHSDTFQSMDQLLPLLPLFDAIVVGPGPGNPNNGAQDMGIISELFENANGKLDEVPILGICLGFQAMCLAQGADVSELNTIKHGQVYEMHLNDAARACGLFSGYPDTFKSTRYHSLHVNAEGIDTLLPLCTTEDENGILLMSAQTKNKPWFGVQYHPESCCSELGGLLVSNFLKLSFINNVKTGRWEKKKLNGEFSDILSRLDRTIDRDPIYKVKEKYPKGEDTTYVKQFEVSEDPKLTFEICNIIREEKFVMSSSVISENTGEWSIIALPNSASQVFTHYGAMKKTTVHYWQDSEISYTLLKKCLDGQDSDLPGSLEVIHEDKSQFWITLGKFMENKIIDNHREIPFIGGLVGILGYEIGQYIACGRCNDDENSLVPDAKLVFINNSIVINHKQGKLYCISLDNTFPVALEQSLRDSFVRKKNIKQSLSWPKYLPEEIDFIITMPDKLDYAKAFKKCQDYMHKGDSYEMCLTTQTKVVPSAVIEPWRIFQTLVQRNPAPFSSFFEFKDIIPRQDETPPVLCFLSTSPERFLKWDADTCELRPIKGTVKKGPQMNLAKATRILKTPKEFGENLMILDLIRNDLYELVPDVRVEEFMSVQEYATVYQLVSVVKAHGLTSASKKTRYSGIDVLKHSLPPGSMTGAPKKITVQLLQDKIESKLNKHVNGGARGVYSGVTGYWSVNSNGDWSVNIRCMYSYNGGTSWQLGAGGAITVLSTLDGELEEMYNKLESNLQIFM", "length": 787, "molWeight": 88544, "crc64": "13117891486B5B0E", "md5": "02F9E6B117540B57A31AB654B717FA93"}}
{"primaryAccession": "P38070", "text": "This is Serine/threonine-protein kinase YPK3 protein, from Baker's yeast, contains 525 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38070", "organism_name": "Baker's yeast", "protein_name": "Serine/threonine-protein kinase YPK3", "length": 525, "firstPublicDate": "1994-10-01", "FUNCTION": "AGC kinase which plays a role in TOR complex 1 (TORC1) signaling pathway which mediates temporal control of cell growth in response to nutrients (PubMed:11062466), Required for phosphorylation of ribosomal protein S6 (RPS6A/RPS6B) at 'Ser-232' and 'Ser-233' (PubMed:25767889)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIFSLDEELHRVSLDDKKNDIKVDYSSAIYNDINHEQGSSITYEESINHLSVHSNAIPLNGMSPAHRMRRRSSAYSKFPILTPPNTRRFSITGSDAMRTNTNRLSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKYWAKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQLQKTTLGPIVPVITDLELAENFDTEFTSMSYEETYTDSKPININSVSKSPDMFKGFSYKASGSYLEKYF", "length": 525, "molWeight": 59591, "crc64": "B8FFE61A44067677", "md5": "BDBEAED1AFA58FA43861BF2049BE6F20"}}
{"primaryAccession": "P38211", "text": "This is GPI mannosyltransferase 2 protein, from Baker's yeast, contains 433 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38211", "organism_name": "Baker's yeast", "protein_name": "GPI mannosyltransferase 2", "length": 433, "firstPublicDate": "1994-10-01", "FUNCTION": "Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis, Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the PIGV family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MIVGLTLYFVLFRSIQYLLVFLTPIRQFDTSTSLLLNELCSSPSEINSYWNKYFWNKLLSWDSVFFIKNITSKNGKPQFEHEYAFSQLWTFFVRLFIKSNNDSIYHALRVGVAIENVLFYLSGIVLYFLTKKIFSQNIRQSQFARTIAKKTSLLFFLTSAAGFLTSIYSEPLSFFFAFVGIWSRECSISVPVLGQFDISWRYWFPYSFISMACFTLASLNRSNCVLLGIYFIFDLIELTKNRKFVKAICFPLLSGSLMFSALLYQQYYLPYKTFCPQRGEWCKSQLFSSIFITKTSLYSYIQSHYWGVGLLKYWTPNNIPNFLFAVPNIIILIYSSIYFSKIYPSYNLKALVWITRALVVIVCFFAHVQILNRIASFLPLHLWYLADRLVKTSDPKKMENPKGDDKIVKFYIYWLAFWIPLQTILFAAFLPPA", "length": 433, "molWeight": 50759, "crc64": "9C81918DF1A37B44", "md5": "B3A407C40CD0A83FBA8321D7851EA79D"}}
{"primaryAccession": "P38212", "text": "This is Protein RCR1 protein, from Baker's yeast, contains 213 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38212", "organism_name": "Baker's yeast", "protein_name": "Protein RCR1", "length": 213, "firstPublicDate": "1994-10-01", "FUNCTION": "Regulates chitin deposition in the cell wall", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGLISYENEAINEVKKADNHHVSKFVTSYYGPSSSSWQSGIWILFVLFVAAVILIILFTFVANRRRRRMGRAPIRGTAWLTPPSYRQSQQQYTGTVQQRTDDYVPEYTETANEHDLGYYDQRGEFHPNDKAAYVAPPPLVQECSSESVNSLERPPAAVVHQANSLDTDYGLTRPSNGRVPAVSDTVEQLERLPGGTTTQEINPPERAKVNARS", "length": 213, "molWeight": 23887, "crc64": "0784FB182C16F1B0", "md5": "2142D388B81A290DD6A2355D453BBC57"}}
{"primaryAccession": "P38228", "text": "This is Mitochondrial chaperone TCM62 protein, from Baker's yeast, contains 572 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38228", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial chaperone TCM62", "length": 572, "firstPublicDate": "1994-10-01", "FUNCTION": "Chaperone, Required for the assembly of succinate dehydrogenase subunits, Ensures mitochondrial gene expression at elevated temperatures and prevents heat-aggregation of the ribosomal subunit VAR1", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the chaperonin (HSP60) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRNCLRKLGNHQTKCSVKTLHTPIYRTKNLQVLRDTLSGIKLLEKIITSSSYNKTLIYEPKYKSKPQVVSSHDTMRLHNVMRELLDSLQVDEATNTRLQSNRPRKLGRVGLQLFMDCIQDNLTATSTSLTCSLLEHYFKYPEKEVTNGIKAGLRYIRDFLAKNKIIVKSQNDVDALVEQLTMSSSDSQSIKRVLKAINYELFSDDIVRVINGNKTYDEVDVSKGWKYPAGILDSNEAYLRSLELPTKKLVSIDKDMLVLMYDGTLRDANKILPTITYARKLRKSVLLIVNGDCTGDALTSVTINNNRNKRENNESRIVVLKYSKKANNDLAPQENLDFIKFLRLPCGYDSIYSPEYSPLVPSKMCADKYYGSIESIKATTGEAFLYNSIDAEAIPNKVPKSFLQNTVTLSIGGHNEIEIDRRRNAIDNCLNNVLCHGLAKGFIPGYGISLLKAIPGLNELKANEPNFMTKVGINAVLSAVILPSEVAFKNAYGYNYYEINSLIAGAINEKSFPMAKFSPNSEPVNTVKDGNLEPWSKMDSCLAGVETFIELLTSCNTIITCVYKKPERHKA", "length": 572, "molWeight": 64252, "crc64": "1AAE3CD22AD8D5BD", "md5": "FA53EBD7AC7737015E2F555ED2715AA5"}}
{"primaryAccession": "P38247", "text": "This is Protein SLM4 protein, from Baker's yeast, contains 162 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38247", "organism_name": "Baker's yeast", "protein_name": "Protein SLM4", "length": 162, "firstPublicDate": "1994-10-01", "FUNCTION": "Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome (PubMed:16732272), Component of the EGO complex, a complex involved in the regulation of microautophagy (PubMed:15989961)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVMLHSKNVKGFLENTLKPYDLHSVDFKTSSLQSSMIITATNGGILSYATSNNDVPKNSINEINSVNNLKMMSLLIKDKWSEDENDTEEQHSNSCYPVEIDSFKTKIYTYEMEDLHTCVAQIPNSDLLLLFIAEGSFPYGLLVIKIERAMRELTDLFGYKLG", "length": 162, "molWeight": 18354, "crc64": "D64ABDE1CDF265FD", "md5": "B33B5BA8C6923D3DADFAB0AF6E280AB1"}}
{"primaryAccession": "P38257", "text": "This is Crossover junction endonuclease MMS4 protein, from Baker's yeast, contains 691 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38257", "organism_name": "Baker's yeast", "protein_name": "Crossover junction endonuclease MMS4", "length": 691, "firstPublicDate": "1994-10-01", "FUNCTION": "Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick, Typical substrates include 3'-flap structures, D-loops, replication forks with regressed leading strands and nicked Holliday junctions, Cleavage probably occurs approximately half a helical turn upstream of the free 5'-end in these structures, May be required in mitosis for the processing of stalled replication fork intermediates arising spontaneously or subsequent to treatment with DNA damaging agents such as methylmethane sulfonate (MMS), camptothecin (CPT) or UV, May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI), This involves consecutive cleavage of D-loops and nicked Holliday junctions leading to sister chromatid crossover, In contrast to MSH4-MSH5 dependent crossover, double Holliday junctions do not seem to be involved, Spore formation and viability are severely impaired in deletion strains", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the EME1/MMS4 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSQIVDFVEDKDSRNDASIQIIDGPSNVEIIALSESMDQDECKRAHVSSAEMIPSSPQRKSVSNDVENVDLNKSIELSAPFFQDISISKLDDFSTTVNSIIDSSLRNENNAKGNAKKLLDDLISDEWSADLESSGKKHNKSQYNLRDIAEKWGVQSLKNPEPIAVDCEYKTQGIGKTNSDISDSPKSQIGAADILFDFPLSPVKHENPTEEKHNSIANENSSPDNSLKPAGKQNHGEDGTSMAKRVYNKGEDEQEHLPKGKKRTIALSRTLINSTKLPDTVELNLSKFLDSSDSITTDVLSTPAKGSNIVRTGSQPIFSNANCFQEAKRSKTLTAEDPKCTKNTAREVSQLENYIAYGQYYTREDSKNKIRHLLKENKNAFKRVNQIYRDNIKARSQMIIEFSPSLLQLFKKGDSDLQQQLAPAVVQSSYNDSMPLLRFLRKCDSIYDFSNDFYYPCDPKIVEENVLILYYDAQEFFEQYTSQKKELYRKIRFFSKNGKHVILILSDINKLKRAIFQLENEKYKARVEQRLSGTEEALRPRSKKSSQVGKLGIKKFDLEQRLRFIDREWHVKIHTVNSHMEFINSLPNLVSLIGKQRMDPAIRYMKYAHLNVKSAQDSTETLKKTFHQIGRMPEMKANNVVSLYPSFQSLLEDIEKGRLQSDNEGKYLMTEAVEKRLYKLFTCTDPNDTIE", "length": 691, "molWeight": 78764, "crc64": "3B3918DD3B2E7E0C", "md5": "73FA6CCAB73CC1EAD9A914F2CFD923C9"}}
{"primaryAccession": "P38287", "text": "This is Mannosyl phosphorylinositol ceramide synthase CSH1 protein, from Baker's yeast, contains 376 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38287", "organism_name": "Baker's yeast", "protein_name": "Mannosyl phosphorylinositol ceramide synthase CSH1", "length": 376, "firstPublicDate": "1994-10-01", "FUNCTION": "Involved in the synthesis of mannosyl phosphorylinositol ceramide (PubMed:12954640), Catalyzes the addition of mannosyl to phosphorylinositol ceramide (PubMed:12954640)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the glycosyltransferase 32 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKKELKILIIANIALLISIIHYTFDLLTLCIDDTSKDALTDEQLNPPNGFNSTFYESPPQLIPKIIHQTYKTNDIPEQWVKGRQKCIDLHPDYTYILWTDEMSDTFIKQEYPWFLDTFRSYEYPIERADAIRYFILSHYGGIYIDLDDGCERRLDPLLKVPAFLRKTSPTGVSNDVMGSVPRHPFFLKVIKSLKHYKKNWYIPYMTIMGSTGPLFISVVWKQYKRWSNTAENGAVRILQPADYKMHNNSFFSISKGSSWHTGDANFMKTLENHILSCVVTGFIFGFFILYGEFTFYTWLCSGPFNNKRYYIQWLSDKFKLHKWKLTSSYKNKEKRRNPTRHEYNSRGKRLRKDSNIPYDSVFLDIEKNHAKFTDLT", "length": 376, "molWeight": 44382, "crc64": "34D992039DA0B796", "md5": "E7C5FBCC2ABF4D15BF2D88E5D69A2BEB"}}
{"primaryAccession": "P38291", "text": "This is Ribonucleases P/MRP protein subunit POP7 protein, from Baker's yeast, contains 140 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38291", "organism_name": "Baker's yeast", "protein_name": "Ribonucleases P/MRP protein subunit POP7", "length": 140, "firstPublicDate": "1994-10-01", "FUNCTION": "Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, Also a component of RNase MRP, which cleaves pre-rRNA sequences", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone-like Alba family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALKKNTHNKSTKRVTKHPSLKTLTHKQIHTTIFVKSTTPYVSALKRINKFLDSVHKQGSSYVAVLGMGKAVEKTLALGCHFQDQKNKKIEVYTKTIEVLDEVITEGQADIDMESDVEDDDKETQLKKRAVSGVELRIYV", "length": 140, "molWeight": 15814, "crc64": "B507BFDC7ED9C95C", "md5": "793554EB23042412A93FED1CC63AF63A"}}
{"primaryAccession": "P38310", "text": "This is Iron transporter FTH1 protein, from Baker's yeast, contains 465 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38310", "organism_name": "Baker's yeast", "protein_name": "Iron transporter FTH1", "length": 465, "firstPublicDate": "1994-10-01", "FUNCTION": "High affinity iron transporter probably involved in transport of intravacuolar stores of iron", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9,A,10,1) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFEDYFSFQIFFIFLRESLEIVVIVSILLTIVKQGLSVEDDSPFEGSSSSAGLPSPNTNTNADSTTAFLQAGPSDGNAIGTSATAANNKSRPLNVEEEEEIYEYSNELRDQDRESDEHTADNVKLYQKLKIQILAGGAFGLLLCMLIGGAFVSIFYHIGTDLWTLSEHYYEGVLSLVASVIISVMGLFFLRMGKLREKFRVKLASIIYSKDNNLLGNKTQKGVKFSEKYSFFILPFITTLREGLEAVVFIGGIGIDQPLSSIPLSMVLATAISTVFGIFFFRYSSSLSLKICLVVATCFLYLIAAGLFSKGVWQLELQDYVNKCNGQDMSEVGNGPGSYDISRSVWHVNCCNGEKDGGWMIFTAIFGWTNSATVGSVISYNAYWLVLICALKLLMIEEKYGYIPYLPISWQKKRIMKRLSIAKASLDLKHHTSELNSSTSEPDSQRRSKDSSVPLIIDSSGSAN", "length": 465, "molWeight": 51420, "crc64": "7B4E620ABC39A053", "md5": "C446CE3FBF280210BFB082407B428509"}}
{"primaryAccession": "P38313", "text": "This is Inner kinetochore subunit AME1 protein, from Baker's yeast, contains 324 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38313", "organism_name": "Baker's yeast", "protein_name": "Inner kinetochore subunit AME1", "length": 324, "firstPublicDate": "1994-10-01", "FUNCTION": "Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis, Component of the inner kinetochore COMA complex, which connects centromere-associated proteins and the outer kinetochore, COMA interacts with other inner kinetochore proteins to form the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CENP-U/AME1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDRDTKLAFRLRGSHSRRTDDIDDDVIVFKTPNAVYREENSPIQSPVQPILSSPKLANSFEFPITTNNVNAQDRHEHGYQPLDAEDYPMIDSENKSLISESPQNVRNDEDLTTRYNFDDIPIRQLSSSITSVTTIDVLSSLFINLFENDLIPQALKDFNKSDDDQFRKLLYKLDLRLFQTISDQMTRDLKDILDINVSNNELCYQLKQVLARKEDLNQQIISVRNEIQELKAGKDWHDLQNEQAKLNDKVKLNKRLNDLTSTLLGKYEGDRKIMSQDSEDDSIRDDSNILDIAHFVDLMDPYNGLLKKINKINENLSNELQPSL", "length": 324, "molWeight": 37462, "crc64": "C53CB31A7B42F6D5", "md5": "FB4067225621FB03AEECE2ED7CA32C97"}}
{"primaryAccession": "P38319", "text": "This is Tyrosyl-DNA phosphodiesterase 1 protein, from Baker's yeast, contains 544 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38319", "organism_name": "Baker's yeast", "protein_name": "Tyrosyl-DNA phosphodiesterase 1", "length": 544, "firstPublicDate": "1994-10-01", "FUNCTION": "DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate, Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue, Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals, Cleaves also 5' phosphotyrosyl adducts resulting from dead-end complexes between DNA and the active site tyrosine of topoisomerase II, Contributes to DNA repair after radiation damage, Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA, May have low 3'exonuclease activity and may be able to remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups, Has no exonuclease activity towards DNA or RNA with a 3'phosphate (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the tyrosyl-DNA phosphodiesterase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRETNFNGTKRKRSDVAEKVAQRWKSVRYSAEMENMAPVNSNNDSDDCVIVSESKIIDLTNQEQDLSERIETNDTAKGAVFKLMKSDFYEREDFMGEVEDMITLKDIFGTETLKRSILFSFQYELDFLLRQFHQNVENITIVGQKGTIMPIEARAMDATLAVILKKVKLIEITMPPFASHHTKLIINFYDNGECKIFLPSNNFTSMETNLPQQVCWCSPLLKIGKEGLPVPFKRSLIEYLNSYHLKDIDELITKSVEEVNFAPLSELEFVYSTPSKFQSSGLLSFYNKLEKLSAGTSASDTAKHYLCQTSSIGTSLSRARDENLWTHLMIPLFTGIMSPPAKDTAGRKKAEILPTNSLINEYSQRKIKPYIIFPTEQEFVTSPLKWSSSGWFHFQYLQKKSYYEMLRNKFKVFYKQDPAMVTRRRGTTPAHSKFYMHCATNSAGPCDASQVFKELEWCLYTSANLSQTAWGTVSRKPRNYEAGVLYHSRRLANTRKVTCRTFTRDRRGCAGNPTHVAVPFTLPVIPYDLAEDECFCLARHEND", "length": 544, "molWeight": 62333, "crc64": "E84C6685312DEC3F", "md5": "51910986B045E175B3065C5F799ADC8A"}}
{"primaryAccession": "P38345", "text": "This is Succinate dehydrogenase assembly factor 4, mitochondrial protein, from Baker's yeast, contains 138 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38345", "organism_name": "Baker's yeast", "protein_name": "Succinate dehydrogenase assembly factor 4, mitochondrial", "length": 138, "firstPublicDate": "1994-10-01", "FUNCTION": "Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol, Binds to the flavoprotein subunit SDH1 in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit SDH2 into the SDH catalytic dimer", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the SDHAF4 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLCAIKSTGYRYPRTGALNLLRGRPFNMATRKITTERIPGPPKLPREEQEEFERLQRIATSQEAIDQYNAQATGDRTKESLNSPLLTKNDIGSFSPEFSKTIPEFEGDVNPKTGEVGGPKQDPLRHGDYSFNGRVTDF", "length": 138, "molWeight": 15504, "crc64": "62289A10A10FBC6E", "md5": "42BCC0DC15CC4D5513C7F6F099AE06A5"}}
{"primaryAccession": "P38574", "text": "This is Uroplakin-3a protein, from Bovine, contains 287 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38574", "organism_name": "Bovine", "protein_name": "Uroplakin-3a", "length": 287, "firstPublicDate": "1994-10-01", "FUNCTION": "Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells, May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells, It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the uroplakin-3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPPLWVVLALGCLRLGSGVNLQPQLASVTFATNNPTLTTVALEKPLCMFDSSAALHGTYEVYLYVLVDSASFRNASVQDSTKTPLSSTFQQTQGGRTGPYKAAAFDLTPCSDSPSLDAVRDVSRASEILNAYLIRVGTNGTCLLDPNFQGLCNPPLSAATEYRFKYVLVNMSSGLVQDQTLWSDPIRTDRLTLYSAIDTWPGRRSGGMIVITSILGSLPFFLLIGFAGAIVLSLVDRGDADGATSHDSQITQEAVPKSLGTSEPSYTSVNRGPSLDRAEVYASKLQD", "length": 287, "molWeight": 30757, "crc64": "177185A017E233B5", "md5": "688696DBDDBD18C737382A9F0114AA9E"}}
{"primaryAccession": "P38633", "text": "This is Mediator of RNA polymerase II transcription subunit 31 protein, from Baker's yeast, contains 127 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38633", "organism_name": "Baker's yeast", "protein_name": "Mediator of RNA polymerase II transcription subunit 31", "length": 127, "firstPublicDate": "1994-10-01", "FUNCTION": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes, Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors, The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II, The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Mediator complex subunit 31 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSTNGNAPATPSSDQNPLPTRFEVELEFIQSLANIQYVTYLLTQQQIWKSPNFKNYLKYLEYWCNPPYSQCIVYPNCLFILKLLNGFMESAIVNEDGLLEGLDELPKIIQLQGPQWMNEMVERWAN", "length": 127, "molWeight": 14741, "crc64": "A2FE3B62ADC14011", "md5": "4DBBE4BA095706193B8CD438114ED799"}}
{"primaryAccession": "P38711", "text": "This is Small ribosomal subunit protein eS27B protein, from Baker's yeast, contains 82 amino acids, has 1 C4-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [37, 59], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "P38711", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS27B", "length": 82, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS27 family", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTVLCTPTGGKAKLSEGTSFRRK", "length": 82, "molWeight": 8865, "crc64": "FCA80130D9A2191E", "md5": "441AA71ABFBC84A3FCF76C6A7A39F9EC"}}
{"primaryAccession": "P38805", "text": "This is Ribosome production factor 1 protein, from Baker's yeast, contains 295 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38805", "organism_name": "Baker's yeast", "protein_name": "Ribosome production factor 1", "length": 295, "firstPublicDate": "1995-02-01", "FUNCTION": "Essential protein, Required for biogenesis of the 60S ribosomal subunit", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALGNEINITNKLKRQEIFADIKHEKNKERHTMRRKRAKEERENPELREQRLKENVTQTIENTRVYDETINKEVEGDEDDLMRYFNSNSNEPPKIFLTTNVNAKKSAYEFANILIEILPNVTFVKRKFGYKLKEISDICIKRNFTDIVIINEDKKKVTGLTFIHLPEGPTFYFKLSSFVEVKKIVGHGRPTSHIPELILNNFQTRLGQTVGRLFQSILPQNPDIEGRQVITLHNQRDYIFFRRHRYVFKDNERVGLQELGPQFTLKLKRLQRGIKEETEWEHKPEMDKEKKKFYL", "length": 295, "molWeight": 35121, "crc64": "EC6EDB2FCE252D4A", "md5": "B18DEE309750A18D31CDF29775671336"}}
{"primaryAccession": "P38806", "text": "This is Chromatin modification-related protein YNG2 protein, from Baker's yeast, contains 282 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [222, 271], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "P38806", "organism_name": "Baker's yeast", "protein_name": "Chromatin modification-related protein YNG2", "length": 282, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A, The NuA4 complex is also involved in DNA repair, Involved in cell cycle progression and meiosis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ING family", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDPSLVLEQTIQDVSNLPSEFRYLLEEIGSNDLKLIEEKKKYEQKESQIHKFIRQQGSIPKHPQEDGLDKEIKESLLKCQSLQREKCVLANTALFLIARHLNKLEKNIALLEEDGVLAPVEEDGDMDSAAEASRESSVVSNSSVKKRRAASSSGSVPPTLKKKKTSRTSKLQNEIDVSSREKSVTPVSPSIEKKIARTKEFKNSRNGKGQNGSPENEEEDKTLYCFCQRVSFGEMVACDGPNCKYEWFHYDCVNLKEPPKGTWYCPECKIEMEKNKLKRKRN", "length": 282, "molWeight": 32086, "crc64": "110E0A2536547D03", "md5": "8F9150C38942E0009EA4D42EBDC53A05"}}
{"primaryAccession": "P38843", "text": "This is Chitin synthase export chaperone protein, from Baker's yeast, contains 316 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38843", "organism_name": "Baker's yeast", "protein_name": "Chitin synthase export chaperone", "length": 316, "firstPublicDate": "1995-02-01", "FUNCTION": "Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the CHS7 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFSDFAAICSKTPLPLCSVIKSKTHLILSNSTIIHDFDPLNLNVGVLPRCYARSIDLANTVIFDVGNAFINIGALGVILIILYNIRQKYTAIGRSEYLYFFQLTLLLIIFTLVVDCGVSPPGSGSYPYFVAIQIGLAGACCWALLIIGFLGFNLWEDGTTKSMLLVRGTSMLGFIANFLASILTFKAWITDHKVATMNASGMIVVVYIINAIFLFVFVICQLLVSLLVVRNLWVTGAIFLGLFFFVAGQVLVYAFSTQICEGFKHYLDGLFFGSICNVFTLMMVYKTWDMTTDDDLEFGVSVSKDGDVVYDNGFM", "length": 316, "molWeight": 34898, "crc64": "9DA1EAFA181B2409", "md5": "F3DA7A688FEF3B7019695F1CA22FBC56"}}
{"primaryAccession": "P38857", "text": "This is Mitochondrial pyruvate carrier 2 protein, from Baker's yeast, contains 129 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38857", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial pyruvate carrier 2", "length": 129, "firstPublicDate": "1995-02-01", "FUNCTION": "Mediates the uptake of pyruvate into mitochondria", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2,A,105) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSTSSVRFAFRRFWQSETGPKTVHFWAPTLKWGLVFAGFSDMKRPVEKISGAQNLSLLSTALIWTRWSFVIKPRNILLASVNSFLCLTAGYQLGRIANYRIRNGDSISQLCSYILSGADESKKEITTGR", "length": 129, "molWeight": 14555, "crc64": "5C1FB3A463DE24A7", "md5": "D6ADE5E1E5DC8AF1D93D1B285D21C7A0"}}
{"primaryAccession": "P38878", "text": "This is Endoplasmic reticulum junction formation protein lunapark protein, from Baker's yeast, contains 278 amino acids, has 1 C4-type; plays a role in ER morphology Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [223, 247], "description": "C4-type; plays a role in ER morphology", "keyword_description": "Zinc finger", "textural_description": "C4-type; plays a role in ER morphology Zinc finger"}], "meta_data": {"primaryAccession": "P38878", "organism_name": "Baker's yeast", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "length": 278, "firstPublicDate": "1995-02-01", "FUNCTION": "Plays a role in tubular endoplasmic reticulum network formation and maintenance, Works in conjunction with the ER shaping proteins (reticulons RTN1 and RTN2, YOP1), and in antagonism to SEY1 to maintain the network in a dynamic equilibrium, May counterbalance SEY1-directed polygon formation by promoting polygon loss through ring closure", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the lunapark family", "domain_description": {"C4-type; plays a role in ER morphology Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFSALGKWVRGSRNDKDFVTKYTADLSQITSQIHQLDVALKKSQSILSQWQSNLTFYGIALTVLALSYTYWEYHGYRPYLVVTALLCIGSLILFKWALTKLYAFYNNNRLRKLAKLRAIHQKKLEKLKEETHYNATSSIIQRFSSGEDQNDDAMVLLDDELNAKYQELNNLKTELEKFKKESHVKGLKKEDSDAWFDKIISVLAGGNELDSTSSLSPFKKIICPQCHWKSNCYRLASKPIIFICPHCNHKIDEVKEREDAIEAKQPAQPSQSEKEKTK", "length": 278, "molWeight": 32063, "crc64": "D896557EEE805C89", "md5": "AE2854CBFC050C0069C8464D6D2E0090"}}
{"primaryAccession": "P39001", "text": "This is Transcriptional regulatory protein UME6 protein, from Baker's yeast, contains 836 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P39001", "organism_name": "Baker's yeast", "protein_name": "Transcriptional regulatory protein UME6", "length": 836, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events, Binds to the URS1 site (5'-AGCCGCCGA-3') and recruits the RPD3 histone deacetylase complex to the promoters to negatively regulate the expression of many genes including CAR1 (arginase), several required for sporulation, mating type switching, inositol metabolism, and oxidative carbon metabolism, Recruits also the ISW2 chromatin remodeling complex to promoters in a second gene repression pathway, Associates with the master regulator of meiosis IME1 in order to activate the expression of meiosis genes, Has both a positive and negative role in regulating phospholipid biosynthesis", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLDKARSQSKHMDESNAAASLLSMETTANNHHYLHNKTSRATLMNSSQDGKKHAEDEVSDGANSRHPTISSASIESLKTTYDENPLLSIMKSTCAPNNTPVHTPSGSPSLKVQSGGDIKDDPKENDTTTTTNTTLQDRRDSDNAVHAAASPLAPSNTPSDPKSLCNGHVAQATDPQISGAIQPQYTATNEDVFPYSSTSTNSNTATTTIVAGAKKKIHLPPPQAPAVSSPGTTAAGSGAGTGSGIRSRTGSDLPLIITSANKNNGKTTNSPMSILSRNNSTNNNDNNSIQSSDSRESSNNNEIGGYLRGGTKRGGSPSNDSQVQHNVHDDQCAVGVAPRNFYFNKDREITDPNVKLDENESKINISFWLNSKYRDEAYSLNESSSNNASSNTDTPTNSRHANTSSSITSRNNFQHFRFNQIPSQPPTSASSFTSTNNNNPQRNNINRGEDPFATSSRPSTGFFYGDLPNRNNRNSPFHTNEQYIPPPPPKYINSKLDGLRSRLLLGPNSASSSTKLDDDLGTAAAVLSNMRSSPYRTHDKPISNVNDMNNTNALGVPASRPHSSSFPSKGVLRPILLRIHNSEQQPIFESNNSTAVFDEDQDQNQDLSPYHLNLNSKKVLDPTFESRTRQVTWNKNGKRIDRRLSAPEQQQQLEVPPLKKSRRSVGNARVASQTNSDYNSLGESSTSSAPSSPSLKASSGLAYTADYPNATSPDFAKSKGKNVKPKAKSKAKQSSKKRPNNTTSKSKANNSQESNNATSSTSQGTRSRTGCWICRLRKKKCTEERPHCFNCERLKLDCHYDAFKPDFVSDPKKKQMKLEEIKKKTKEAKRRAMKKK", "length": 836, "molWeight": 91124, "crc64": "0DDA0A6B4A157182", "md5": "8274641C99ED010A4E530B1215E27D73"}}
{"primaryAccession": "P39723", "text": "This is Spindle pole component SPC72 protein, from Baker's yeast, contains 622 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P39723", "organism_name": "Baker's yeast", "protein_name": "Spindle pole component SPC72", "length": 622, "firstPublicDate": "1995-02-01", "FUNCTION": "Spindle pole body component that acts as the gamma-tubulin complex-binding protein of the SPB outer plaque, Anchors cytoplasmic microtubules at the at the half bridge of the spindle pole body (SPB) and accordingly functions in nuclear position and spindle orientation, including anaphase spindle migration into the bud, Recruits KIN4 kinase to both SPBs when cytoplasmic microtubules are defective, Links cytoplasmic microtubules with spindle orientation checkpoint (SPOC) components and, therefore, could function as part of the sensors of spindle orientation defects, Is strictly required for mating and karyogamy", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVRRWIPSGRHLRNNDNTGDDDDSEFTNSMDSGMSIPSLRDSMTTRSSHNDPIKPALMNDSNKVKNLEKELTNAKIKIQVLYEYIRRIPNKDGNAPSLGNDTDFRNSIIEGLNLEINKLKQDLKAKEVEYQDTLQFVQENLENSESIVNTINHLLSFILTHFNEQDENAHLLDKEERETLEETLELSSDYVLEKMDTLSKFIIQFLQDFLHSKSRAESKQDKEEFLSLAQSSPAGSQLESRDSPSSKEENTDGGYQNDEIHDSNNHIDTENVMANSTSLPISAVESRFEKTLDTQLEIVIENLHKEYDQFINSIRLKFEKSQKLEKIIASKLNEQSHLLDSLELEENSSSVIEKQDHLISQLKEKIESQSVLINNLEKLKEDIIKMKQNEKVLTKELETQTKINKLKENNWDSYINDLEKQINDLQIDKSEEFHVIQNQLDKLDLENYQLKNQLNTLDNQKLILSQYESNFIKFNQNLLLHLDSIFNILQKILQESSIAQFDRKMKSIKSVPNALKNLNLIQPKLESLYTFIETALESIINSYISSLISMETPEQPHQQGNELTATPNKELTLRIEELQRRWISERERRKLDANASEARIKALEQENESLRSKLFNLSINNP", "length": 622, "molWeight": 72106, "crc64": "33A858B9ADCAD633", "md5": "31A1A828A53540768FAC1AF68A80375E"}}
{"primaryAccession": "P39923", "text": "This is Nitrogen permease regulator 2 protein, from Baker's yeast, contains 615 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P39923", "organism_name": "Baker's yeast", "protein_name": "Nitrogen permease regulator 2", "length": 615, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis (PubMed:21454883), Mediates inactivation of the TORC1 complex in response to amino acid starvation (PubMed:19521502, PubMed:26510498), Post-transcriptional regulator of nitrogen permeases (PubMed:19521502), May be involved in putative NPR1-dependent phosphorylation of nitrogen permeases or in the processing and targeting of nitrogen permeases at the level of the endoplasmic reticulum (PubMed:19521502)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the NPR2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLSYFQGFVPIHTIFYSVFHPTEGSKIKYEFPPNNLKNHGINFNTFKNYIIPKPILCHKLITFKYGTYRIVCYPVTINSPIYARNFFSFNFVFVFPYDCETSPYEPAITRLGKMFKVLEEQNQLLSKSERDPVFFDLKVLENSTTTPSTAGPSSTPNPSSNTTPTHPTSEKDTKDMRSSRYSDLIKDLGLPQSAFSIQDLLMRIFQDLNNYSECLIPIDEGNAVDIKIFPLLRPPTTCVSLEDVPLSSVNLKKIIDVNWDPTMMSIVPYIDGLNSIAKISKLSNSDPGLVIECIRHLIYYKCVTLSDIFQFSNIYAPSSLIRNFLTDPLMASDCQSYVTFPEVSKISNLPLNKSLGSGDQDSPSFSVRRKSKSSSIPSNPDSRTTSFSSTSRVSQNSSLNSSFSSIYKDWRQSQTSCSSSNIHVINNRNRFLPTRSCLFDLYRSLSQGQTLKTWYESKYMILKENNIDIRRFITFGLEKRIIYRCYSFPVMINAGSREPKEMTPIITKDLVNNDKLLEKRNHNHLLSATGSRNTAQSGNLKPERPSKVSFEMQRVSSLATGKSTMPKLSDEEEGILEESIRNAETFDKICVLLSKPKLEVESYLNELGEFKVINS", "length": 615, "molWeight": 69859, "crc64": "58CA4983B0BAF7BA", "md5": "F630900831030411E141F73F23DCAACD"}}
{"primaryAccession": "P39936", "text": "This is Eukaryotic initiation factor 4F subunit p130 protein, from Baker's yeast, contains 914 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P39936", "organism_name": "Baker's yeast", "protein_name": "Eukaryotic initiation factor 4F subunit p130", "length": 914, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the eIF4F complex, which interacts with the mRNA cap structure and serves as an initial point of assembly for the translation apparatus, Stimulates translation by interaction with polyadenylate-binding protein PAB1, bringing the 5'- and 3'-ends of the mRNA in proximity, The formation of this circular mRNP structure appears to be critical for the synergistic effects of the cap and the poly(A) tail in facilitating translation initiation, recycling of ribosomes, and mRNA stability, TIF4632 is probably essential when TIF4631 is missing", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic initiation factor 4G family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTDQRGPPPPHPQQANGYKKFPPHDNQYSGANNSQPNNHYNENLYSAREPHNNKQYQSKNGKYGTNKYNNRNNSQGNAQYYNNRFNNGYRLNNNDYNPAMLPGMQWPANYYAPQMYYIPQQMVPVASPPYTHQPLNTNPEPPSTPKTTKIEITTKTGERLNLKKFHEEKKASKGEEKNDGVEQKSKSGTPFEKEATPVLPANEAVKDTLTETSNEKSTSEAENTKRLFLEQVRLRKAAMERKKNGLISETEKKQETSNHDNTDTTKPNSVIESEPIKEAPKPTGEANEVVIDGKSGASVKTPQHVTGSVTKSVTFNEPENESSSQDVDELVKDDDTTEISDTTGGKTVNKSDDETINSVITTEENTVKETEPSTSDIEMPTVSQLLETLGKAQPISDIYEFAYPENVERPDIKYKKPSVKYTYGPTFLLQFKDKLKFRPDPAWVEAVSSKIVIPPHIARNKPKDSGRFGGDFRSPSMRGMDHTSSSRVSSKRRSKRMGDDRRSNRGYTSRKDREKAAEKAEEQAPKEEIAPLVPSANRWIPKSRVKKTEKKLAPDGKTELFDKEEVERKMKSLLNKLTLEMFDSISSEILDIANQSKWEDDGETLKIVIEQIFHKACDEPHWSSMYAQLCGKVVKDLDPNIKDKENEGKNGPKLVLHYLVARCHEEFEKGWADKLPAGEDGNPLEPEMMSDEYYIAAAAKRRGLGLVRFIGYLYCLNLLTGKMMFECFRRLMKDLNNDPSEETLESVIELLNTVGEQFEHDKFVTPQATLEGSVLLDNLFMLLQHIIDGGTISNRIKFKLIDVKELREIKHWNSAKKDAGPKTIQQIHQEEEQLRQKKNSQRSNSRFNNHNQSNSNRYSSNRRNMQNTQRDSFASTKTGSFRNNQRNARKVEEVSQAPRANMFDALMNNDGDSD", "length": 914, "molWeight": 103899, "crc64": "BF5E9805CD47908E", "md5": "646D94D1CDC4671AD441C578E9917CE8"}}
{"primaryAccession": "P39952", "text": "This is Mitochondrial inner membrane protein OXA1 protein, from Baker's yeast, contains 402 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P39952", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial inner membrane protein OXA1", "length": 402, "firstPublicDate": "1995-02-01", "FUNCTION": "Mitochondrial inner membrane insertase that mediates the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the inner membrane, Links mitoribosomes with the inner membrane (PubMed:22904327), Forms pores capable of accommodating translocating protein segments (PubMed:22829595), Essential for the activity and assembly of cytochrome c oxidase (PubMed:22904327), Plays a central role in the translocation and export of the N-terminal part of the COX2 protein into the mitochondrial intermembrane space", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the OXA1/ALB3/YidC family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFKLTSRLVTSRFAASSRLATARTIVLPRPHPSWISFQAKRFNSTGPNANDVSEIQTQLPSIDELTSSAPSLSASTSDLIANTTQTVGELSSHIGYLNSIGLAQTWYWPSDIIQHVLEAVHVYSGLPWWGTIAATTILIRCLMFPLYVKSSDTVARNSHIKPELDALNNKLMSTTDLQQGQLVAMQRKKLLSSHGIKNRWLAAPMLQIPIALGFFNALRHMANYPVDGFANQGVAWFTDLTQADPYLGLQVITAAVFISFTRLGGETGAQQFSSPMKRLFTILPIISIPATMNLSSAVVLYFAFNGAFSVLQTMILRNKWVRSKLKITEVAKPRTPIAGASPTENMGIFQSLKHNIQKARDQAERRQLMQDNEKKLQESFKEKRQNSKIKIVHKSNFINNKK", "length": 402, "molWeight": 44816, "crc64": "108890B8F2EE67ED", "md5": "540D0439C3CA4FB46F024912CA9D9F5C"}}
{"primaryAccession": "P39968", "text": "This is Vacuolar protein 8 protein, from Baker's yeast, contains 578 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P39968", "organism_name": "Baker's yeast", "protein_name": "Vacuolar protein 8", "length": 578, "firstPublicDate": "1995-02-01", "FUNCTION": "Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the beta-catenin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGSCCSCLKDSSDEASVSPIADNEREAVTLLLGYLEDKDQLDFYSGGPLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQVSREVLEPILILLQSQDPQIQVAACAALGNLAVNNENKLLIVEMGGLEPLINQMMGDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSKHIRVQRNATGALLNMTHSEENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLAQTEPRLVSKLVSLMDSPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVRLLDYKDSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDSPVSVQSEISACFAILALADVSKLDLLEANILDALIPMTFSQNQEVSGNAAAALANLCSRVNNYTKIIEAWDRPNEGIRGFLIRFLKSDYATFEHIALWTILQLLESHNDKVEDLVKNDDDIINGVRKMADVTFERLQRSGIDVKNPGSNNNPSSNDNNSNNNDTGSEHQPVEDASLELYNITQQILQFLH", "length": 578, "molWeight": 63208, "crc64": "B2E75774B47E5933", "md5": "E9C5DE15814E0872B8392CA436067C3D"}}
{"primaryAccession": "P40014", "text": "This is Kinetochore protein SPC25 protein, from Baker's yeast, contains 221 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40014", "organism_name": "Baker's yeast", "protein_name": "Kinetochore protein SPC25", "length": 221, "firstPublicDate": "1995-02-01", "FUNCTION": "Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SPC25 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASIDAFSDLERRMDGFQKDVAQVLARQQNHARQQLQQFQAEMRQLHNQHQHLIDELQRLATQRTALQQQIHAAQQATNTTREQWRSYHERESELSRRQSTLAAQSRELDSLLQQRGKECVQLRARWAAQSGNDAAEVALYERLLQLRVLPGASDVHDVRFVFGDDSRCWIEVAMHGDHVIGNSHPALDPKSRATLEHVLTVQGDLAAFLVVARDMLLASL", "length": 221, "molWeight": 25244, "crc64": "1BED6CCFF330A5D8", "md5": "18B33191A7DBD88F2048FD71B908C79D"}}
{"primaryAccession": "P40047", "text": "This is Aldehyde dehydrogenase 5, mitochondrial protein, from Baker's yeast, contains 520 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40047", "organism_name": "Baker's yeast", "protein_name": "Aldehyde dehydrogenase 5, mitochondrial", "length": 520, "firstPublicDate": "1995-02-01", "FUNCTION": "Minor mitochondrial aldehyde dehydrogenase isoform, Plays a role in regulation or biosynthesis of electron transport chain components, Involved in the biosynthesis of acetate during anaerobic growth on glucose", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the aldehyde dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLSRTRAAAPNSRIFTRSLLRLYSQAPLRVPITLPNGFTYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFETKWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCARGDVALVSKYLRSCGGWADKIYGNVIDTGKNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADTVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGARHGSKGYFVKPTVFADVKEDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSVRIAIDKPIR", "length": 520, "molWeight": 56693, "crc64": "DCD382A1157F800A", "md5": "22BE64E0624346EF4F9EB3E7AB1D3C91"}}
{"primaryAccession": "P40072", "text": "This is E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8 protein, from Baker's yeast, contains 274 amino acids, has 1 RING-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [206, 250], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "P40072", "organism_name": "Baker's yeast", "protein_name": "E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8", "length": 274, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the SUMO-targeted ubiquitin ligase (STUbL) complex SLX5/SLX8 that mediates ubiquitination and subsequent desumoylation of sumoylated proteins and proteins containing SUMO-like domains for their degradation (PubMed:11139495, PubMed:16325482, PubMed:18032921, PubMed:17669696, PubMed:17848550, PubMed:18499666, PubMed:18948542, PubMed:31015336), The STUbL complex SLX5/SLX8 stimulates ubiquitin conjugating enzymes, including UBC1, UBC4, UBC5 and UBC13-MMS2, and mediates the proteolytic down-regulation of sumoylated proteins (PubMed:18032921), The STUbL complex SLX5/SLX8 is involved in ubiquitin-mediated degradation of histone variant CSE4, preventing mislocalization to euchromatin (PubMed:26960795), The complex plays an essential role in maintenance of chromosome stability and links SUMO-dependent ubiquitination to a centromere-specific function during mitosis (PubMed:23785440), The complex is involved in proteolysis of spindle positioning protein KAR9 and ensures correct spindle function by regulating levels of microtubule-associated proteins (PubMed:26906737), During replication, the complex helps to prevent DNA lesions via recombination and has a role in localizing the DNA damage protein DCD2 (PubMed:16325482, PubMed:17591698), The complex especially ubiquitinates the nuclease YEN1 and prevents persistent accumulation of a fraction of YEN1 associated with sites of activity in late G2/M and helps maintain the balance between pro- and anti-crossover pathways during homologous recombination (PubMed:30479332), It is also involved in ubiquitin-mediated degradation of DNA repair proteins RAD52 and RAD57 (PubMed:18032921), Finally, the complex is recruited to distinct genomic hotspots of non-H2B protein ubiquitination (ub-hotspots) by the sumoylated transcription factor-like protein EUC1 where it ubiquitinates EUC1 and presumably other targets (PubMed:31015336)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MARRPDNQNPEGENLRIKRVRLESVRQNDEEEENEVSRTQNIVTDNRHDSPEAVVEIIGERALENTSEEDGDDDLSLFRALEEDPGSDHNTSNNDSGNHDRETMHTEEPEASSGNNITLTNNVEELHTMDVLSQTANTPSASPMLDAAPPTTKPGTNSKEQTVDLTADAIDLDAEEQQVLQISDDDFQEETKEAPKEYGAAKDYRCPICFEPPETALMTLCGHVFCCPCLFQMVNSSRTCRQFGHCALCRSKVYLKDVRLIILRKKQVKKKVKS", "length": 274, "molWeight": 30764, "crc64": "358DB6D137155DC1", "md5": "5D5F740FD6B7086F16DD0E0FD505CB16"}}
{"primaryAccession": "P40094", "text": "This is Conserved oligomeric Golgi complex subunit 3 protein, from Baker's yeast, contains 801 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40094", "organism_name": "Baker's yeast", "protein_name": "Conserved oligomeric Golgi complex subunit 3", "length": 801, "firstPublicDate": "1995-02-01", "FUNCTION": "Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking, COG is located at the cis- Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events, COG3 is also involved in actin cytoskeleton organization", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the COG3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MARSRKNSLVRDIASHPTIPESQTIVGLLDDSYLFDKLKKLSLAVENSDSLQRTDVSEGCSEVNGSEATTSADVKKTNKYLYYTTYLDQLNIKIDEYKVVLDQTRQVNDQLDSSIKKFRKISQDTGAFIEETKTIYEKQSKLSNLTESIPKALHYFEVLDPIMRRLNHATSPAIVKKSSFTTMLATIDESLRFLDENSDLKDAAAYRIKFKQCLIRACELISHFLTNLLKQTNQEILDKTKNKNSLTGLPSTTRDAFLYSKFYTIADTFKIQVSEIVKRSNEKAYNKYHDELNSILYECFNHYFQTRLRLLTPVIWSHIDEIVVKDKDQGLVKFIQDGKVYFQQLCADEYKLFVEFFPEKECRFKINQWFLQLCEPLYDSIRVRVLKETDICTLCDSVTLFAPYYEFEEGSEEYVKQFTDIQYDKLFEPIVQKVQARLILRVQIYVQQNILSYRPTRDVFMISNRRRKSKTSLQGGNEDATTSDDNPDPLLESYLSSFKNRSILPISPNDADDKSIDSEESTDKISQLQTYYPPLLKTLALLSKIYEMINSVVFDDLAHHVVHDCIVSLRNAYDMVIKSSAGKSDFNNLDISLAYLKNLLMLRDSIQNFNIQYTVNETYLDFSGVEGFFKSLKENGRNVLKKTKSSSILTLARELVPKVVNNMVDARTELISELRNVIKDFTESTSLELIDDTLDINSDEDLLSKNVKLRENIKARLPRIYEQILNYIDDQEIVTNLLDAVQELITQSYSKYYETITELAENGKFAKDQVADVMYLDVFTDFFAKEVADLLRNGDIDTITK", "length": 801, "molWeight": 92544, "crc64": "C7AFBE99010FE571", "md5": "8EDC2740CC0F71AB11F426A276BD5F64"}}
{"primaryAccession": "P40215", "text": "This is External NADH-ubiquinone oxidoreductase 1, mitochondrial protein, from Baker's yeast, contains 560 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40215", "organism_name": "Baker's yeast", "protein_name": "External NADH-ubiquinone oxidoreductase 1, mitochondrial", "length": 560, "firstPublicDate": "1995-02-01", "FUNCTION": "External NADH dehydrogenase required for optimum cellular growth with a number of nonfermentable carbon sources, including ethanol, With NDE2, performes the mitochondrial oxidation of cytosolic NADH under these growth conditions, Regulates the mitochondrial glycerol-3-phosphate dehydrogenase, GUT2, also involved in cytosolic NADH oxidation", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the NADH dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIRQSLMKTVWANSSRFSLQSKSGLVKYAKNRSFHAARNLLEDKKVILQKVAPTTGVVAKQSFFKRTGKFTLKALLYSALAGTAYVSYSLYREANPSTQVPQSDTFPNGSKRKTLVILGSGWGSVSLLKNLDTTLYNVVVVSPRNYFLFTPLLPSTPVGTIELKSIVEPVRTIARRSHGEVHYYEAEAYDVDPENKTIKVKSSAKNNDYDLDLKYDYLVVGVGAQPNTFGTPGVYEYSSFLKEISDAQEIRLKIMSSIEKAASLSPKDPERARLLSFVVVGGGPTGVEFAAELRDYVDQDLRKWMPELSKEIKVTLVEALPNILNMFDKYLVDYAQDLFKEEKIDLRLKTMVKKVDATTITAKTGDGDIENIPYGVLVWATGNAPREVSKNLMTKLEEQDSRRGLLIDNKLQLLGAKGSIFAIGDCTFHPGLFPTAQVAHQEGEYLAQYFKKAYKIDQLNWKMTHAKDDSEVARLKNQIVKTQSQIEDFKYNHKGALAYIGSDKAIADLAVGEAKYRLAGSFTFLFWKSAYLAMCLSFRNRVLVAMDWAKVYFLGRDSSI", "length": 560, "molWeight": 62774, "crc64": "10B1795E12E29C34", "md5": "9D2F4C69287F2433E80F50945FE94B64"}}
{"primaryAccession": "P40344", "text": "This is Autophagy-related protein 3 protein, from Baker's yeast, contains 310 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40344", "organism_name": "Baker's yeast", "protein_name": "Autophagy-related protein 3", "length": 310, "firstPublicDate": "1995-02-01", "FUNCTION": "E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy, Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8, The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE), This step is required for the membrane association of ATG8, The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt), The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ATG3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIRSTLSSWREYLTPITHKSTFLTTGQITPEEFVQAGDYLCHMFPTWKWNEESSDISYRDFLPKNKQFLIIRKVPCDKRAEQCVEVEGPDVIMKGFAEDGDEDDVLEYIGSETEHVQSTPAGGTKDSSIDDIDELIQDMEIKEEDENDDTEEFNAKGGLAKDMAQERYYDLYIAYSTSYRVPKMYIVGFNSNGSPLSPEQMFEDISADYRTKTATIEKLPFYKNSVLSVSIHPCKHANVMKILLDKVRVVRQRRRKELQEEQELDGVGDWEDLQDDIDDSLRVDQYLIVFLKFITSVTPSIQHDYTMEGW", "length": 310, "molWeight": 35887, "crc64": "52CCFB216B18CF0C", "md5": "3921CFFA80A1A71EB482351E75A8F037"}}
{"primaryAccession": "P40495", "text": "This is Homoisocitrate dehydrogenase, mitochondrial protein, from Baker's yeast, contains 371 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40495", "organism_name": "Baker's yeast", "protein_name": "Homoisocitrate dehydrogenase, mitochondrial", "length": 371, "firstPublicDate": "1995-02-01", "FUNCTION": "Catalyzes the NAD(+)-dependent conversion of homoisocitrate to alpha-ketoadipate", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFRSVATRLSACRGLASNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVKVLKEQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGEKGKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGQATLTVTHKSNVLSQSDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNEAAQDIYKAVDANLREGSIKTPDLGGKASTQQVVDDVLSRL", "length": 371, "molWeight": 40069, "crc64": "43CAFA86F75ED3C6", "md5": "23F372340E03EE58CDFF26AE8E02FAC6"}}
{"primaryAccession": "P40498", "text": "This is U3 small nucleolar RNA-associated protein 25 protein, from Baker's yeast, contains 721 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40498", "organism_name": "Baker's yeast", "protein_name": "U3 small nucleolar RNA-associated protein 25", "length": 721, "firstPublicDate": "1995-02-01", "FUNCTION": "DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the UTP25 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSDSSVREKNDNFRGYRKRGRQELRKIKRSSARTEGGSTETLEDVAEDIDHRSDEDEVSDVDSGDDFDIEDEEGKKEKVYDALLTILKSEHPEPKRRRREADESNKAPAEVGEDEHENTEHGPVDDQLEIENGLLGNHEDDNDDDSSGDEKDIDSEDEQDPFESHFNQVPEKFVDKLSNAFKTKSVKYKSVKGSLSDSESYIYAKPVVIGEEALVESPYRSSSIYSYFLKQRLKVQNGLLDKKTDPLTALQKKLVDPMFQYKDILYEYDSYEKDEDEYRDLYALHVLNHIYKTRDRILKNNQRLQDNPDTEHLDQGFTRPKVLIVVPTREVAYRVVDKIISKSGIDQVDKKGKFYDQFRDDSLPPKSKPKSFQHIFRGNTNDFFVVGLKFTRKAIKLYSNFYQSDIIVCSPLGIQMILENTDKKKRQDDFLSSIELMVIDQLHSIEYQNISHIFTIFDHLNKIPDQQHEADFSRIRMWYINEQAKLFRQTMVFTKYISPAANSLINGRCRNMAGRWKNHKVIGSENSSIGQSGLKIRQIFQRFDIIGNSIIEEPDYRFKFFTSVIIPGIVKSTGYEDGILIYIPDYTDFIRIRNYMKEKTTILFGDINEYSSQRQLNANRSLFQQGRLKVMLYTERLHHYRRYEIKGVKSVVFYKPPNNPEFYNEVVRFIGKNAFLGNTDLNISTVRCIYSKLDGLSLERIVGTKRAAVLSHAQKEIYEFK", "length": 721, "molWeight": 83991, "crc64": "301BC87BCA027104", "md5": "590EF250A43809C2E2ACABE9D597B7F7"}}
{"primaryAccession": "P40564", "text": "This is DnaJ-like protein 1 protein, from Baker's yeast, contains 432 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40564", "organism_name": "Baker's yeast", "protein_name": "DnaJ-like protein 1", "length": 432, "firstPublicDate": "1995-02-01", "FUNCTION": "Required for peroxisomal protein import which maintains the function of peroxisomes", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the DnaJ family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVVDTEYYDLLGVSTTASSIEIKKAYRKKSIQEHPDKNPNDPTATERFQAISEAYQVLGDDDLRAKYDKYGRKEAIPQGGFEDAAEQFSVIFGGDAFASYIGELMLLKNLQKTEELNAEDEAEKEKENVETMEESPADGKTNGTTNAVDAALGNTNEKDDKNKARTTSGNLTVHDGNKKNEQVGAEAKKKKTKLEQFEEEQEVEKQKRVDQLSKTLIERLSILTESVYDDACKDSFKKKFEEEANLLKMESFGLDILHTIGDVYYEKAEIFLASQNLFGMGGIFHSMKAKGGVFMDTLRTVSAAIDAQNTMKELEKMKEASTNNEPLFDKDGNEQIKPTTEELAQQEQLLMGKVLSAAWHGSKYEITSTLRGVCKKVLEDDSVSKKTLIRRAEAMKLLGEVFKKTFRTKVEQEEAQIFEELVAEATKKKRHT", "length": 432, "molWeight": 48575, "crc64": "8127D6886BC78B96", "md5": "3FE044557870B0F6CD39921EEAFE3B4A"}}
{"primaryAccession": "P40571", "text": "This is Ribonuclease P protein subunit RPR2 protein, from Baker's yeast, contains 144 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40571", "organism_name": "Baker's yeast", "protein_name": "Ribonuclease P protein subunit RPR2", "length": 144, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the eukaryotic/archaeal RNase P protein component 4 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGKKAHGGKMKPEIDENGTLLVPPPRTIANQDHFHRLNYLYQISAYQTRARQKARTDAHTPLARNYIKSMDLISKKTKTSLLPTIKRTICKKCHRLLWTPKKLEITSDGALSVMCGCGTVKRFNIGADPNYRTYSEREGNLLNS", "length": 144, "molWeight": 16344, "crc64": "91AEF14F80D76148", "md5": "992C852E79F3633F0CD906C7EE7CAFFE"}}
{"primaryAccession": "P40847", "text": "This is Switch-activating protein 1 protein, from Fission yeast, contains 254 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40847", "organism_name": "Fission yeast", "protein_name": "Switch-activating protein 1", "length": 254, "firstPublicDate": "1995-02-01", "FUNCTION": "Has a role in chromosome organization and integrity where it is involved in chromosome segregation, Has a role in sister chromatid cohesion and condensation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEAPKMELKSYKRKNASLSPSSSPAKAQRTHLSLEEKIKLMRLVVRHKHELVDRKTSEFYAKIARIGYEDEGLAIHTESACRNQIISIMRVYEQRLAHRQPGMKTTPEEDELDQLCDEWKARLSELQQYREKFLVGKRKCDCNDEINERLKKLTEEQQNVDMLVAKVNFLSKHLHDNEEKLMQVNAKMDEVLAENKRLQQLLDHNDLLSKLEPPSAYAPHGVNMGTNMGANMGANMNAIRGGLHSSISPNLGDH", "length": 254, "molWeight": 29127, "crc64": "570DCE20C3C20847", "md5": "8B5B7F99C13BFF599129BFC3F164F233"}}
{"primaryAccession": "P40936", "text": "This is Indolethylamine N-methyltransferase protein, from Mouse, contains 264 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40936", "organism_name": "Mouse", "protein_name": "Indolethylamine N-methyltransferase", "length": 264, "firstPublicDate": "1995-02-01", "FUNCTION": "Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity), Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide, Plays an important role in the detoxification of selenium compounds", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the class I-like SAM-binding methyltransferase superfamily, NNMT/PNMT/TEMT family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEGKVYIGGEDYEKEFTPKDYLTTYYSFHSGPVAEQEIVKFSLQNLYQTFSTGGVGGDVLIDIGSGPTIYQLLSACEVFREIIVTDYTPQNLQELQKWLKKEPGAYDWSSIVQHACELEGDRSRWQEKEAKLRRTVTRVLRCDVTKTPPLGSAQVPLADCVLTFLAMECACPDIDTYRAALRRLAGLLKPGGHLVTLVTLRFQHYMVGPKKFSGVYLEKEVVEKAIQDAGCQVLKCNCVSLSYSEAYCSHDGLCFVVARKGPSA", "length": 264, "molWeight": 29460, "crc64": "58AC5BA580AFB2EE", "md5": "18D51542F4451A55A661B02CEA166EFD"}}
{"primaryAccession": "P41056", "text": "This is Large ribosomal subunit protein eL33B protein, from Baker's yeast, contains 107 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P41056", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein eL33B", "length": 107, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eL33 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAESHRLYVKGKHLSYQRSKRVNNPNVSLIKIEGVATPQEAQFYLGKRIAYVYRASKEVRGSKIRVMWGKVTRTHGNSGVVRATFRNNLPAKTFGASVRIFLYPSNI", "length": 107, "molWeight": 12168, "crc64": "D33E8388903B5196", "md5": "DB6574F901126722F8AB684C5A73C672"}}
{"primaryAccession": "P41183", "text": "This is B-cell lymphoma 6 protein homolog protein, from Mouse, contains 707 amino acids, has 6 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [519, 542], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [547, 569], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [575, 597], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [603, 625], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [631, 653], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [659, 682], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "P41183", "organism_name": "Mouse", "protein_name": "B-cell lymphoma 6 protein homolog", "length": 707, "firstPublicDate": "1995-02-01", "FUNCTION": "Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions, Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes, Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors, In GC B-cells, represses genes that function in differentiation, inflammation, apoptosis and cell cycle control, also autoregulates its transcriptional expression and up-regulates, indirectly, the expression of some genes important for GC reactions, such as AICDA, through the repression of microRNAs expression, like miR155, An important function is to allow GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response, In follicular helper CD4(+) T-cells (T(FH) cells), promotes the expression of T(FH)-related genes but inhibits the differentiation of T(H)1, T(H)2 and T(H)17 cells, Also required for the establishment and maintenance of immunological memory for both T- and B-cells, Suppresses macrophage proliferation through competition with STAT5 for STAT-binding motifs binding on certain target genes, such as CCL2 and CCND2, In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners, Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 6}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEISPEGFCILLDFMYTSRLNLREGNIMAVMTTAMYLQMEHVVDTCRKFIKASEAEMAPALKPPREEFLNSRMLMPHDIMAYRGREVVENNMPLRNTPGCESRAFAPPLYSGLSTPPASYPMYSHLPLSTFLFSDEELRDAPRMPVANPFPKERALPCDSARQVPNEYSRPAMEVSPSLCHSNIYSPKEAVPEEARSDIHYSVPEGPKPAVPSARNAPYFPCDKASKEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGSEQAELGRLSPRAYPAPPACQPPMEPANLDLQSPTKLSASGEDSTIPQASRLNNLVNRSLAGSPRSSSESHSPLYMHPPKCTSCGSQSPQHTEMCLHTAGPTFPEEMGETQSEYSDSSCENGTFFCNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSAADLPPELPKAC", "length": 707, "molWeight": 78982, "crc64": "2051DD808D32D5EC", "md5": "5D018D98AF880EDFE6BA4B8B1A73404E"}}
{"primaryAccession": "P41546", "text": "This is Transcriptional activator HAC1 protein, from Baker's yeast, contains 238 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P41546", "organism_name": "Baker's yeast", "protein_name": "Transcriptional activator HAC1", "length": 238, "firstPublicDate": "1995-11-01", "FUNCTION": "Transcriptional activator involved in the unfolded protein response (UPR) pathway, Recognizes and binds to the UPR element (UPRE) in the promoter of UPR-regulated genes such as KAR2, PDI1, EUG1 and FKB2, Increases the synthesis of endoplasmic reticulum-resident proteins required for protein folding as well as components of the secretory pathway", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEMTDFELTSNSQSNLAIPTNFKSTLPPRKRAKTKEEKEQRRIERILRNRRAAHQSREKKRLHLQYLERKCSLLENLLNSVNLEKLADHEDALTCSHDAFVASLDEYRDFQSTRGASLDTRASSHSSSDTFTPSPLNCTMEPATLSPKSMRDSASDQETSWELQMFKTENVPESTTLPAVDNNNLFDAVASPLADPLCDDIAGNSLPFDNSIDLDNWRNPEAQSGLNSFELNDFFITS", "length": 238, "molWeight": 26905, "crc64": "81C01ACB3E2531B1", "md5": "D4E9C0CF4B1D1F1E415BDE595A219A50"}}
{"primaryAccession": "P41593", "text": "This is Parathyroid hormone/parathyroid hormone-related peptide receptor protein, from Mouse, contains 591 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P41593", "organism_name": "Mouse", "protein_name": "Parathyroid hormone/parathyroid hormone-related peptide receptor", "length": 591, "firstPublicDate": "1995-11-01", "FUNCTION": "Receptor for parathyroid hormone and for parathyroid hormone-related peptide (PubMed:8197183), The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGTARIAPSLALLLCCPVLSSAYALVDADDVFTKEEQIFLLHRAQAQCDKLLKEVLHTAANIMESDKGWTPASTSGKPRKEKAPGKFYPESKENKDVPTGSRRRGRPCLPEWDNIVCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTIFGWGLPAVFVAVWVGVRATLANTGCWDLSSGHKKWIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVFMALPYTEVSGTLWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRAGLSLPLSPRLLPATTNGHSQLPGHAKPGAPAIENETIPVTMTVPKDDGFLNGSCSGLDEEASGSARPPPLLQEEWETVM", "length": 591, "molWeight": 66372, "crc64": "C2E6CCAF2ABAFEEF", "md5": "D46754712F17ABB517C3A4619B9DADD3"}}
{"primaryAccession": "P41903", "text": "This is Peroxisomal acyl-coenzyme A thioester hydrolase 1 protein, from Baker's yeast, contains 349 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P41903", "organism_name": "Baker's yeast", "protein_name": "Peroxisomal acyl-coenzyme A thioester hydrolase 1", "length": 349, "firstPublicDate": "1995-11-01", "FUNCTION": "Acyl-coenzyme A (acyl-CoA) thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH, Contributes to growth on fatty acids", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the C/M/P thioester hydrolase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSASKMAMSNLEKILELVPLSPTSFVTKYLPAAPVGSKGTFGGTLVSQSLLASLHTVPLNFFPTSLHSYFIKGGDPRTKITYHVQNLRNGRNFIHKQVSAYQHDKLIFTSMILFAVQRSKEHDSLQHWETIPGLQGKQPDPHRYEEATSLFQKEVLDPQKLSRYASLSDRFQDATSMSKYVDAFQYGVMEYQFPKDMFYSARHTDELDYFVKVRPPITTVEHAGDESSLHKHHPYRIPKSITPENDARYNYVAFAYLSDSYLLLTIPYFHNLPLYCHSFSVSLDHTIYFHQLPHVNNWIYLKISNPRSHWDKHLVQGKYFDTQSGRIMASVSQEGYVVYGSERDIRAKF", "length": 349, "molWeight": 40260, "crc64": "F1B5A51C9A46783E", "md5": "9AFA5BF05A3FF6120841B433FC3E66AB"}}
{"primaryAccession": "P42260", "text": "This is Glutamate receptor ionotropic, kainate 2 protein, from Rat, contains 908 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P42260", "organism_name": "Rat", "protein_name": "Glutamate receptor ionotropic, kainate 2", "length": 908, "firstPublicDate": "1995-11-01", "FUNCTION": "Independent of its ionotropic glutamate receptor activity, acts as a thermoreceptor conferring sensitivity to cold temperatures (By similarity), Functions in dorsal root ganglion neurons (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glutamate-gated ion channel (TC 1,A,10,1) family, GRIK2 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKIISPVLSNLVFSRSIKVLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRRLPGKETMA", "length": 908, "molWeight": 102470, "crc64": "7F430E2D8B2E982B", "md5": "0EB475061A240CDD26A1E2D369968491"}}
{"primaryAccession": "P42699", "text": "This is Plastocyanin major isoform, chloroplastic protein, from Mouse-ear cress, contains 167 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P42699", "organism_name": "Mouse-ear cress", "protein_name": "Plastocyanin major isoform, chloroplastic", "length": 167, "firstPublicDate": "1995-11-01", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I, Seems to be the major plastocyanin in Arabidopsis", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASVTSATVAIPSFTGLKASTIKSSATVRIQTAAVASPKLTVKSSLKNFGVAAVAAAASIALAGNAMAIEVLLGGGDGSLAFIPNDFSIAKGEKIVFKNNAGYPHNVVFDEDEIPSGVDVAKISMDEQDLLNGAGETYEVALTEPGTYSFYCAPHQGAGMVGKVTVN", "length": 167, "molWeight": 16984, "crc64": "00BE1D33D47E35D6", "md5": "1832F19919D7E7D7CF75C70782ADC158"}}
{"primaryAccession": "P42775", "text": "This is G-box-binding factor 2 protein, from Mouse-ear cress, contains 360 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P42775", "organism_name": "Mouse-ear cress", "protein_name": "G-box-binding factor 2", "length": 360, "firstPublicDate": "1995-11-01", "FUNCTION": "Binds to the G-box motif (5'-CCACGTGG-3') of the rbcS-1A gene promoter, G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control, GBF2 is found to bind asymmetrically to the G-box", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGSNEEGNPTNNSDKPSQAAAPEQSNVHVYHHDWAAMQAYYGPRVGIPQYYNSNLAPGHAPPPYMWASPSPMMAPYGAPYPPFCPPGGVYAHPGVQMGSQPQGPVSQSASGVTTPLTIDAPANSAGNSDHGFMKKLKEFDGLAMSISNNKVGSAEHSSSEHRSSQSSENDGSSNGSDGNTTGGEQSRRKRRQQRSPSTGERPSSQNSLPLRGENEKPDVTMGTPVMPTAMSFQNSAGMNGVPQPWNEKEVKREKRKQSNRESARRSRLRKQAETEQLSVKVDALVAENMSLRSKLGQLNNESEKLRLENEAILDQLKAQATGKTENLISRVDKNNSVSGSKTVQHQLLNASPITDPVAAS", "length": 360, "molWeight": 38789, "crc64": "060EEFCB168BBB17", "md5": "13CB6D88B62ABF87B3B1CBEBEBBB7555"}}
{"primaryAccession": "P43005", "text": "This is Excitatory amino acid transporter 3 protein, from Human, contains 524 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P43005", "organism_name": "Human", "protein_name": "Excitatory amino acid transporter 3", "length": 524, "firstPublicDate": "1995-11-01", "FUNCTION": "Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7914198, PubMed:7521911, PubMed:8857541, PubMed:26690923, PubMed:21123949, PubMed:33658209), Can also transport L-cysteine (PubMed:21123949), Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:7521911, PubMed:8857541, PubMed:26690923, PubMed:33658209), Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:8857541, PubMed:26690923), Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli (PubMed:21123949), Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity), Contributes to glutathione biosynthesis and protection against oxidative stress via its role in L-glutamate and L-cysteine transport (By similarity), Negatively regulated by ARL6IP5 (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2,A,23) family, SLC1A1 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGKPARKGCEWKRFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMTEESFTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFALESTILDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF", "length": 524, "molWeight": 57100, "crc64": "FC6244ADC9EA228F", "md5": "D3924A6C6C23942E8AE7383F0C991D9A"}}
{"primaryAccession": "P43082", "text": "This is Hevein-like preproprotein protein, from Mouse-ear cress, contains 212 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P43082", "organism_name": "Mouse-ear cress", "protein_name": "Hevein-like preproprotein", "length": 212, "firstPublicDate": "1995-11-01", "FUNCTION": "Fungal growth inhibitors, Neither CB-HEL nor CD-HEL have chitinase activity, but both have antimicrobial activities, CD-HEL has RNase, but no DNase activity", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKIRLSITIILLSYTVATVAGQQCGRQGGGRTCPGNICCSQYGYCGTTADYCSPTNNCQSNCWGSGPSGPGESASNVRATYHFYNPAQNNWDLRAVSAYCSTWDADKPYAWRSKYGWTAFCGPAGPRGQASCGKCLRVKNTRTNAAVTVRIVDQCSNGGLDLDVAMFNQIDTDGFGYQQGHLIVDYQFVDCGNELIGQPDSRNMLVSAIDRV", "length": 212, "molWeight": 22937, "crc64": "1EDAD140A21AA692", "md5": "D0FD3E2782C5E39B5E433BDE8AA65B1C"}}
{"primaryAccession": "P43587", "text": "This is Type 1 phosphatases regulator YPI1 protein, from Baker's yeast, contains 155 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P43587", "organism_name": "Baker's yeast", "protein_name": "Type 1 phosphatases regulator YPI1", "length": 155, "firstPublicDate": "1995-11-01", "FUNCTION": "Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control, Regulates the nuclear localization of type 1 phosphatase GLC7 and SDS22, and is involved in the regulation of mRNA 3'-end processing, May also regulate the activity of type 1 phosphatase PPZ1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the YPI1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGNQMAMGSEQQQTVGSRTVSVEEVPAVLQLRATQDPPRSQEAMPTRHNVRWEENVIDNENMNKKKTKICCIFHPQNEDEEECNHHSDDDGSSSSGSSSSESENEKDLDFNERRQRRLERRHRKLEKKRSYSPNAYEIQPDYSEYRRKQQEKKD", "length": 155, "molWeight": 18187, "crc64": "E191184DCD5EF8A1", "md5": "D495F1A247C1C85D337BAB4B313D7F2C"}}
{"primaryAccession": "P43603", "text": "This is LAS seventeen-binding protein 3 protein, from Baker's yeast, contains 459 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P43603", "organism_name": "Baker's yeast", "protein_name": "LAS seventeen-binding protein 3", "length": 459, "firstPublicDate": "1995-11-01", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the SH3YL1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGINNPIPRSLKSETKKAAKILASFVKPNQVFGADQVIPPDVLKRAKGLAIITILKAGFLFSGRAGSGVIVARLKDGTWSAPSAIAMAGAGAGGMVGIELTDFVFILNTQDAVKSFSEFGTITLGGNVSVSAGPLGRSAEAAASASAGGVAAVFAYSKSKGLFAGVSVEGSAIIERREANRKFYGDNCTAKMILSGRIRPPPAVDPLFRVLESRAFNYRPSNGGRGSFDDDEDDYYDDDDYYNDIPSSFSSTDASSTRPNTRSTRRRAQSGSRYTFDDDDDDDDYGTGYSRNSRLAPTNSGGSGGKLDDPSGASSYYASHRRSGTAQSRARSSRNRWADDEYDDYDDDYESGYRRGNGRDRTKDREVDDLSNRFSKSRISSASTPQTSQGRFTAPTSPSTSSPKAVALYSFAGEESGDLPFRKGDVITILKKSDSQNDWWTGRVNGREGIFPANYVELV", "length": 459, "molWeight": 49344, "crc64": "F486C787B5771AAC", "md5": "8E627D3A32376B7CB5F86973763E0A33"}}
{"primaryAccession": "P45846", "text": "This is Dermatopontin protein, from Pig, contains 183 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P45846", "organism_name": "Pig", "protein_name": "Dermatopontin", "length": 183, "firstPublicDate": "1995-11-01", "FUNCTION": "Seems to mediate adhesion by cell surface integrin binding, May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment, Enhances TGFB1 activity, Inhibits cell proliferation (By similarity), Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the dermatopontin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "QYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPHGQVVVAVRSIFNKKEGSDRQWNYACMPTPQSLGEPSECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPGHYGEEMDMISYNYDYYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFANV", "length": 183, "molWeight": 21994, "crc64": "5FE4FD477242D710", "md5": "9C4187BEA751EB6B0A350E5E8AFCC2C6"}}
{"primaryAccession": "P45895", "text": "This is Chondroitin sulfate synthase mig-22 protein, from Caenorhabditis elegans, contains 804 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P45895", "organism_name": "Caenorhabditis elegans", "protein_name": "Chondroitin sulfate synthase mig-22", "length": 804, "firstPublicDate": "1995-11-01", "FUNCTION": "Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity, Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer (By similarity), Required together with sqv-5 for the biosynthesis of chondroitin (PubMed:15485872), Chondroitin is involved in organogenesis of the vulva, maturation of the gonad, and neural development (PubMed:15485872, PubMed:16982046), May have a specific role in unc-6/netrin-mediated dorsal guidance of gonadal distal tip cells (PubMed:16982046), Glycosyltransferase activity is weak (PubMed:15485872)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the chondroitin N-acetylgalactosaminyltransferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVGGGRTGIHLLLGFLIGAALALFFFSSTPSIDLTSSLAAFTSCQNQETETNVLEPSALEKGRVYKDLSEHWIVHQDDMPAPPHNQDATPKVTRTRFAATELGTRERVMAAVMAESALALSINATLGRHVPRVHLFADSSRIDNDLAQLTNLSPYKLNGQKTHSMVLGLLFNMTVHNNYDWFLLAKDSTYINPFVLLRMIDTMNWNEPVVMGEAAEDGSGRCRLDTGMLLSQPAMHALMNNRNACNNFALAADDDQLAFEKCIQIATNLTCKPLHQGVRYEVWRGAERADSPAAHDSIEDWKHSPAFKRALAVPRLLSDADASALHDYFVRVEMQRADREIIKMEAELSRLAEQEARETGEAISWPPALPPYAKPPNRYQVSTWEYFTMTELFRSEPNQNVRRLEGKDFDDVAEVVVAARQQVESEEPELEFVQLRNGYRVFDPRRGMDYMVDLTYRKTVNEMPEVDNRFESDNEAAHEESLKEIVVERRVHVSRMIASTQLMNQAPYVKEDTDVTVVIPVASEKDVLPARKLLARQARLCLFPTEEARKTRMVVAVFPLIESRSVTAITNDMEELKRRCKRSLLETDVLPVHPAVSTEGKGTAAAAALDDAVDRYGANTIYLLLSPHADVQKEFFDRARINTIKHYQVFFPVPFVEYHPTISGMEMTEKEEKETPTEQAREAALSRLRDGVEPKRKRTLIVQKEHGRFDSQDFSCFAVYGVDYVTARAKFGQNERRNDLISAFLGQDSIHVLRAVEPTLRIRYHKRSCDMESIDTEDIARCLDSKKENVAAKDQLAKLLFHEK", "length": 804, "molWeight": 91036, "crc64": "C799999A4C4C6314", "md5": "5B5D68DBEC4BE2539A7B9A62A2E69E56"}}
{"primaryAccession": "P46014", "text": "This is Protein phosphatase 2C 70 protein, from Mouse-ear cress, contains 581 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P46014", "organism_name": "Mouse-ear cress", "protein_name": "Protein phosphatase 2C 70", "length": 581, "firstPublicDate": "1995-11-01", "FUNCTION": "Dephosphorylates the Ser/Thr receptor-like kinase RLK5, May function as a signaling component in a pathway involving RLK5 (PubMed:15592873), Binds and dephosphorylates CLAVATA1 (CLV1), Functions as a negative regulator of the CLV1 signaling in plant development (PubMed:9294234, PubMed:9701578), Dephosphorylates SERK1 receptor kinase on threonine residues in the A-loop, Dephosphorylation of SERK1 controls SERK1 internalization (PubMed:12101128), Component of a signaling pathway which mediates adaptation to NaCl stress, Is not a component of the SALT OVERLY SENSITIVE (SOS) pathway (PubMed:18162596)", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAMIGMNIIGLFMVLMLLLISLIILFACKPWRYFSRFRSSSRFSSTFKVGDLQRPLISDDGNLIQGQTSEVTREYDLEGACYQNDGLLHSSLTEGRFYKQRLPSSSPHFSQGESFVLEVISEPSDNALVGQTLKLPAEKGSLAEVQTYDWQNNRNENLQYNLEKDRLINLSPRLVEDQRSWLFLEVIAGPAIGLQHAVNSTSSSKLPVKLGRVSPSDLALKDSEVSGKHAQITWNSTKFKWELVDMGSLNGTLVNSHSISHPDLGSRKWGNPVELASDDIITLGTTTKVYVRISSQNEFQIPFKIGVASDPMAMRRGGRKLPMEDVCHYKWPLPGANKFGLFCVCDGHGGSGAAQSAIKIIPEVLANILSDSLRKEKVLSKRDASDVLRDMFAKTEARLEEHQYEGCTATVLLVWKDNEENFFAQCANLGDSACVIHLGGRYIQMTEDHRVVSLSERKRFQEAGLALRDGETRLFGINLARMLGDKFPKQQDSRFSAEPYISEPLRIDQSSKDVFAVLASDGLWDVVSPKKAVQLVLQMRDKERGRESSAEKIANGLLNEARAMRTKDNTSIIYLDFDTSL", "length": 581, "molWeight": 64911, "crc64": "EE0C2A41E55E100D", "md5": "6553A4F4915701481B3D5008D54BC319"}}
{"primaryAccession": "P46367", "text": "This is Potassium-activated aldehyde dehydrogenase, mitochondrial protein, from Baker's yeast, contains 519 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P46367", "organism_name": "Baker's yeast", "protein_name": "Potassium-activated aldehyde dehydrogenase, mitochondrial", "length": 519, "firstPublicDate": "1995-11-01", "FUNCTION": "Potassium-activated aldehyde dehydrogenase involved in acetate formation during anaerobic growth on glucose", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the aldehyde dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFSRSTLCLKTSASSIGRLQLRYFSHLPMTVPIKLPNGLEYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSSRGDVDLVINYLKSSAGFADKIDGRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAVRAKLDE", "length": 519, "molWeight": 56724, "crc64": "E7D9944EA25F948E", "md5": "CFFBEA20B1941A12A2A55330164298FC"}}
{"primaryAccession": "P46654", "text": "This is Small ribosomal subunit protein uS2B protein, from Baker's yeast, contains 252 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P46654", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein uS2B", "length": 252, "firstPublicDate": "1995-11-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102), uS2 is required for the assembly and/or stability of the 40S ribosomal subunit, Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (PubMed:9973221, PubMed:14627813)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the universal ribosomal protein uS2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTYGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRLDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRNPEEVEQVAEEAAAAEEGEEEEVKEEVTEGQAEATEWAEENADNVEW", "length": 252, "molWeight": 27962, "crc64": "B9B7CDFB335EFAC3", "md5": "CDD8DF3CB537520A6C5E89D85DCDBA9E"}}
{"primaryAccession": "P46943", "text": "This is Translation factor GUF1, mitochondrial protein, from Baker's yeast, contains 645 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P46943", "organism_name": "Baker's yeast", "protein_name": "Translation factor GUF1, mitochondrial", "length": 645, "firstPublicDate": "1995-11-01", "FUNCTION": "Promotes mitochondrial protein synthesis, May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes, Binds to mitochondrial ribosomes in a GTP-dependent manner", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, LepA subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLKFRIRPVRHIRCYKRHAYFLRYNHTTTPAQKLQAQIEQIPLENYRNFSIVAHVDHGKSTLSDRLLEITHVIDPNARNKQVLDKLEVERERGITIKAQTCSMFYKDKRTGKNYLLHLIDTPGHVDFRGEVSRSYASCGGAILLVDASQGIQAQTVANFYLAFSLGLKLIPVINKIDLNFTDVKQVKDQIVNNFELPEEDIIGVSAKTGLNVEELLLPAIIDRIPPPTGRPDKPFRALLVDSWYDAYLGAVLLVNIVDGSVRKNDKVICAQTKEKYEVKDIGIMYPDRTSTGTLKTGQVGYLVLGMKDSKEAKIGDTIMHLSKVNETEVLPGFEEQKPMVFVGAFPADGIEFKAMDDDMSRLVLNDRSVTLERETSNALGQGWRLGFLGSLHASVFRERLEKEYGSKLIITQPTVPYLVEFTDGKKKLITNPDEFPDGATKRVNVAAFHEPFIEAVMTLPQEYLGSVIRLCDSNRGEQIDITYLNTNGQVMLKYYLPLSHLVDDFFGKLKSVSRGFASLDYEDAGYRISDVVKLQLLVNGNAIDALSRVLHKSEVERVGREWVKKFKEYVKSQLYEVVIQARANNKIIARETIKARRKDVLQKLHASDVSRRKKLLAKQKEGKKHMKTVGNIQINQEAYQAFLRR", "length": 645, "molWeight": 73188, "crc64": "BA1C371CCFECDC9B", "md5": "4346707C864AED3F0C4DF1BC5556CBD5"}}
{"primaryAccession": "P46990", "text": "This is Large ribosomal subunit protein uL22B protein, from Baker's yeast, contains 184 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P46990", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein uL22B", "length": 184, "firstPublicDate": "1995-11-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the universal ribosomal protein uL22 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MARYGATSTNPAKSASARGSYLRVSFKNTRETAQAINGWELTKAQKYLDQVLDHQRAIPFRRFNSSIGRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAANAEAKGLDATKLYVSHIQVNQAPKQRRRTYRAHGRINKYESSPSHIELVVTEKEEAVAKAAEKKVVRLTSRQRGRIAAQKRISA", "length": 184, "molWeight": 20551, "crc64": "26F908D90715221D", "md5": "3D73DD6214CFF7787FD87A610CF21BA3"}}
{"primaryAccession": "P47013", "text": "This is Dihydrosphingosine 1-phosphate phosphatase LCB3 protein, from Baker's yeast, contains 409 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P47013", "organism_name": "Baker's yeast", "protein_name": "Dihydrosphingosine 1-phosphate phosphatase LCB3", "length": 409, "firstPublicDate": "1996-02-01", "FUNCTION": "Dihydrosphingosine 1-phosphate phosphatase required for efficient ceramide synthesis from exogenous sphingoid bases (PubMed:10477278, PubMed:10563329, PubMed:10856228, PubMed:11278643, PubMed:11967828, PubMed:12493772, PubMed:12684378, PubMed:12786943, PubMed:9195906, PubMed:9353337, PubMed:9419344, PubMed:25345524), Involved in endocytosis and calcium-mediated signaling (PubMed:10856228, PubMed:11278643)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the type 2 lipid phosphate phosphatase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVDGLNTSNIRKRARTLSNPNDFQEPNYLLDPGNHPSDHFRTRMSKFRFNIREKLLVFTNNQSFTLSRWQKKYRSAFNDLYFTYTSLMGSHTFYVLCLPMPVWFGYFETTKDMVYILGYSIYLSGFFKDYWCLPRPRAPPLHRITLSEYTTKEYGAPSSHTANATGVSLLFLYNIWRMQESSVMVQLLLSCVVLFYYMTLVFGRIYCGMHGILDLVSGGLIGIVCFIVRMYFKYRFPGLRIEEHWWFPLFSVGWGLLLLFKHVKPVDECPCFQDSVAFMGVVSGIECCDWLGKVFGVTLVYNLEPNCGWRLTLARLLVGLPCVVIWKYVISKPMIYTLLIKVFHLKDDRNVAARKRLEATHKEGASKYECPLYIGEPKIDILGRFIIYAGVPFTVVMCSPVLFSLLNIA", "length": 409, "molWeight": 47372, "crc64": "E0CD7D0F169447C3", "md5": "470237A045A06CBA0A675B0C4076F793"}}
{"primaryAccession": "P47082", "text": "This is Vacuolar amino acid transporter 1 protein, from Baker's yeast, contains 602 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P47082", "organism_name": "Baker's yeast", "protein_name": "Vacuolar amino acid transporter 1", "length": 602, "firstPublicDate": "1996-02-01", "FUNCTION": "Required for the vacuolar uptake of large neutral amino acids including tyrosine, glutamine, asparagine, isoleucine and leucine, Requires ATP for function", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the amino acid/polyamine transporter 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPEQEPLSPNGRKRSEVHYISIPLNRGSAFSPDDSVSQFQSDGFMTRRQSILDHPVGSFKGVNSLSRFATSLRRANSFRNIELNADNERSFFKESNDETYDPDTLAPALDGRRLSVTLNNAGRPRITNLANNDRVSTASMAIHDDDYGSIQNSTIGDSGSILRPTASLTEMMSGGAGRRFTNNDMDSIVVKRVEGVDGKVVTLLAGQSTAPQTIFNSINVLIGIGLLALPLGLKYAGWVIGLTMLAIFALATFCTAELLSRCLDTDPTLISYADLGYAAFGTKGRALISALFTLDLLGSGVSLVILFGDSLNALFPQYSTTFFKIVSFFIVTPPVFIPLSVLSNISLLGILSTTGTVLVICCCGLYKSSSPGSLVNPMETSMWPIDLKHLCLSIGLLSACWGGHAVFPNLKTDMRHPDKFKDCLKTTYKITSVTDIGTAVIGFLMFGNLVKDEITKNVLLTEGYPKFVYGLISALMTIIPIAKTPLNARPIVSVLDVLMNVQHIDEAASAIKRRAAKGLQVFNRIFINVVFVLIAINFPEFDKIIAFLGAGLCFTICLILPCWFYLRLCKTTIKPWERVACHVTICISVVLSTLGVGAAIIS", "length": 602, "molWeight": 65346, "crc64": "C2F321E76C21C2B4", "md5": "FFB1E8A51D2A2FA7F377867BEC7C7574"}}
{"primaryAccession": "P47154", "text": "This is CAAX prenyl protease 1 protein, from Baker's yeast, contains 453 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P47154", "organism_name": "Baker's yeast", "protein_name": "CAAX prenyl protease 1", "length": 453, "firstPublicDate": "1996-02-01", "FUNCTION": "Proteolytically removes the C-terminal three residues of farnesylated A-factor mating pheromone, Also acts to cleave the N-terminal extension of the pheromone, Does not act on Ras", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the peptidase M48A family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFDLKTILDHPNIPWKLIISGFSIAQFSFESYLTYRQYQKLSETKLPPVLEDEIDDETFHKSRNYSRAKAKFSIFGDVYNLAQKLVFIKYDLFPKIWHMAVSLLNAVLPVRFHMVSTVAQSLCFLGLLSSLSTLVDLPLSYYSHFVLEEKFGFNKLTVQLWITDMIKSLTLAYAIGGPILYLFLKIFDKFPTDFLWYIMVFLFVVQILAMTIIPVFIMPMFNKFTPLEDGELKKSIESLADRVGFPLDKIFVIDGSKRSSHSNAYFTGLPFTSKRIVLFDTLVNSNSTDEITAVLAHEIGHWQKNHIVNMVIFSQLHTFLIFSLFTSIYRNTSFYNTFGFFLEKSTGSFVDPVITKEFPIIIGFMLFNDLLTPLECAMQFVMSLISRTHEYQADAYAKKLGYKQNLCRALIDLQIKNLSTMNVDPLYSSYHYSHPTLAERLTALDYVSEKKKN", "length": 453, "molWeight": 52324, "crc64": "331CC9AE2D7C99DA", "md5": "4F8A470E7A49A211E1B2F33B8A68D545"}}
{"primaryAccession": "P47821", "text": "This is RNA polymerase II holoenzyme cyclin-like subunit protein, from Baker's yeast, contains 323 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P47821", "organism_name": "Baker's yeast", "protein_name": "RNA polymerase II holoenzyme cyclin-like subunit", "length": 323, "firstPublicDate": "1996-02-01", "FUNCTION": "Component of the SRB8-11 complex, The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription, The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator, It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex, The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5, The SSN3/SRB10 and SSN8/SRB11 kinase-cyclin pair may also positively and negatively regulate numerous transcriptional activators in response to changes in nutritional and physiological conditions", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the cyclin family, Cyclin C subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGSFWTSTQRHHWQYTKASLAKERQKLWLLECQLFPQGLNIVMDSKQNGIEQSITKNIPITHRDLHYDKDYNLRIYCYFLIMKLGRRLNIRQYALATAHIYLSRFLIKASVREINLYMLVTTCVYLACKVEECPQYIRTLVSEARTLWPEFIPPDPTKVTEFEFYLLEELESYLIVHHPYQSLKQIVQVLKQPPFQITLSSDDLQNCWSLINDSYINDVHLLYPPHIIAVACLFITISIHGKPTKGSSLASAASEAIRDPKNSSSPVQIAFNRFMAESLVDLEEVMDTIQEQITLYDHWDKYHEQWIKFLLHTLYLRPASAI", "length": 323, "molWeight": 37791, "crc64": "2BA16A3374CCF207", "md5": "9EB804A77B6345E85AA038951408B34F"}}
{"primaryAccession": "P47866", "text": "This is Corticotropin-releasing factor receptor 2 protein, from Rat, contains 411 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P47866", "organism_name": "Rat", "protein_name": "Corticotropin-releasing factor receptor 2", "length": 411, "firstPublicDate": "1996-02-01", "FUNCTION": "G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3, Has high affinity for UCN, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase, Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDAALLLSLLEANCSLALAEELLLDGWGEPPDPEGPYSYCNTTLDQIGTCWPQSAPGALVERPCPEYFNGIKYNTTRNAYRECLENGTWASRVNYSHCEPILDDKQRKYDLHYRIALIINYLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRNITWFLLQLIDHEVHEGNEVWCRCVTTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIIVAWAVGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYCFFNGEVRSALRKRWHRWQDHHALRVPVARAMSIPTSPTRISFHSIKQTAAV", "length": 411, "molWeight": 47693, "crc64": "F0BA7795F8C37AFE", "md5": "3F3E4A23A16E399DC7B47201F0E96A73"}}
{"primaryAccession": "P47896", "text": "This is Cholesteryl ester transfer protein protein, from Crab-eating macaque, contains 493 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P47896", "organism_name": "Crab-eating macaque", "protein_name": "Cholesteryl ester transfer protein", "length": 493, "firstPublicDate": "1996-02-01", "FUNCTION": "Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles, Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:24293641), Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLAATVLTLALLGNVHACSKGTSHKAGIVCRITKPALLVLNQETAKVIQSAFQRANYPNITGEKAMMLLGQVKYGLHNIQISHLSIASSRVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWGLGIDQSVDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINIISNIMADFVQTRAASILSDGDIGVDISLTGDPIITASYLESHHKGYFIYKNVSEDLPLPTFSPALLGDSRMLYFWFSEQVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPRISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIMTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESVQSFLQSMITTVGIPEVMSRLEAVFTALMNSKGLSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS", "length": 493, "molWeight": 54743, "crc64": "7E82BE3C2A8FAE0D", "md5": "B74BD760CDA82B3ECACC17116DED8E26"}}
{"primaryAccession": "P48003", "text": "This is Histone H2A.Z protein, from Fission yeast, contains 139 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P48003", "organism_name": "Fission yeast", "protein_name": "Histone H2A.Z", "length": 139, "firstPublicDate": "1996-02-01", "FUNCTION": "Variant histone H2A which can replace H2A in some nucleosomes, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, Important for chromosomal structure and function, possibly including a role in controlling the fidelity of chromosomal segregation during mitosis, Plays an important role in maintaining a silenced chromatin state at centromeres and in the architecture of anaphase chromosomes", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGGGKGKHVGGKGGSKIGERGQMSHSARAGLQFPVGRVRRFLKAKTQNNMRVGAKSAVYSAAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAGGGVLPHINKQLLIRTKEKYPEEEEII", "length": 139, "molWeight": 15025, "crc64": "6D88B7ADABAD7E83", "md5": "9929883032CF44A49929ECE76BB45558"}}
{"primaryAccession": "P48044", "text": "This is Vasopressin V2 receptor protein, from Bovine, contains 370 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P48044", "organism_name": "Bovine", "protein_name": "Vasopressin V2 receptor", "length": 370, "firstPublicDate": "1996-02-01", "FUNCTION": "Receptor for arginine vasopressin (PubMed:7698346, PubMed:8257689), The activity of this receptor is mediated by G proteins which activate adenylate cyclase, Involved in renal water reabsorption (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFMASTTSAVPWHLSQPTPAGNGSEGELLTARDPLLAQAELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAHRHGGGTHWNRPVLLAWAFSLLFSLPQLFIFAQRDVDGSGVLDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLGPGPVPRAGGPRRGCRPGSPAEGARVSAAVAKTVKMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCTWRRAPPSPGPQEESCATASSFLAKDTPS", "length": 370, "molWeight": 40236, "crc64": "5FDCCC2CD21DD4AE", "md5": "CB2BA30201C8D729992C9D65536D1C7E"}}
{"primaryAccession": "P48048", "text": "This is ATP-sensitive inward rectifier potassium channel 1 protein, from Human, contains 391 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P48048", "organism_name": "Human", "protein_name": "ATP-sensitive inward rectifier potassium channel 1", "length": 391, "firstPublicDate": "1996-02-01", "FUNCTION": "In the kidney, probably plays a major role in potassium homeostasis, Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it, Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages, The inward rectification is mainly due to the blockage of outward current by internal magnesium, This channel is activated by internal ATP and can be blocked by external barium", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the inward rectifier-type potassium channel (TC 1,A,2,1) family, KCNJ1 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNASSRNVFDTLIRVLTESMFKHLRKWVVTRFFGHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGKYRVDFHNFSKTVEVETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNETDDTKM", "length": 391, "molWeight": 44795, "crc64": "DF01C89B16BE6205", "md5": "5A16E8A8AE8C7CB607D00958B3200AD0"}}
{"primaryAccession": "P48765", "text": "This is Sodium/calcium exchanger 1 protein, from Bovine, contains 970 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P48765", "organism_name": "Bovine", "protein_name": "Sodium/calcium exchanger 1", "length": 970, "firstPublicDate": "1996-02-01", "FUNCTION": "Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:1416984), Contributes to Ca(2+) transport during excitation-contraction coupling in muscle, In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum, SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline, Required for normal embryonic heart development and the onset of heart contractions", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2,A,19) family, SLC8 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLQFSLSPTLSMGFHVIAMVALLFSHVDHISAETEMEGEGNETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVDSFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVAENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVKVSLEASEDGILEASHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLYGQPVFRKVHAREHPLPSTIITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTRLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFACTIALKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF", "length": 970, "molWeight": 108027, "crc64": "7C29153D1F87DDBE", "md5": "B58F55580A68F1EC4B0F6C7077001A1F"}}
{"primaryAccession": "P48766", "text": "This is Sodium/calcium exchanger 1 protein, from Guinea pig, contains 970 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P48766", "organism_name": "Guinea pig", "protein_name": "Sodium/calcium exchanger 1", "length": 970, "firstPublicDate": "1996-02-01", "FUNCTION": "Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:7986817), Contributes to Ca(2+) transport during excitation-contraction coupling in muscle, In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum, SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline, Required for normal embryonic heart development and the onset of heart contractions (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2,A,19) family, SLC8 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRLSLSPTYSLGFHLLAMMTLLISHVDHITAETEMVEEGNETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVAENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHISTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKHLYGQPVLRKVHARDHPIPSTVITIADEYDDKQPLTSKEEEERRIAELGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF", "length": 970, "molWeight": 108072, "crc64": "72D364CB8D157739", "md5": "11FDFC3EAB2A2438D9BFB3109E49B4DC"}}
{"primaryAccession": "P48985", "text": "This is Transcription factor Atoh1 protein, from Mouse, contains 351 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P48985", "organism_name": "Mouse", "protein_name": "Transcription factor Atoh1", "length": 351, "firstPublicDate": "1996-02-01", "FUNCTION": "Transcriptional regulator, Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1, Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRLLHAEEWAEVKELGDHHRHPQPHHVPPLTPQPPATLQARDLPVYPAELSLLDSTDPRAWLTPTLQGLCTARAAQYLLHSPELGASEAAAPRDEADSQGELVRRSGCGGLSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPNVGEQPPPPTASCKNDHHHLRTASSYEGGAGASAVAGAQPAPGGGPRPTPPGPCRTRFSGPASSGGYSVQLDALHFPAFEDRALTAMMAQKDLSPSLPGGILQPVQEDNSKTSPRSHRSDGEFSPHSHYSDSDEAS", "length": 351, "molWeight": 37854, "crc64": "596E03DF23C3BF96", "md5": "21BC07473ED4E8B9969070409572FFB4"}}
{"primaryAccession": "P49166", "text": "This is Large ribosomal subunit protein eL37A protein, from Baker's yeast, contains 88 amino acids, has 1 C4-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [19, 37], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "P49166", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein eL37A", "length": 88, "firstPublicDate": "1996-02-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eL37 family", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASKASA", "length": 88, "molWeight": 9850, "crc64": "274D249361EBE5E5", "md5": "DF70A8A13F3CC4F392D5673FA7A8F022"}}
{"primaryAccession": "P49736", "text": "This is DNA replication licensing factor MCM2 protein, from Human, contains 904 amino acids, has 1 C4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [329, 355], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "P49736", "organism_name": "Human", "protein_name": "DNA replication licensing factor MCM2", "length": 904, "firstPublicDate": "1996-10-01", "FUNCTION": "Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells, Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built (PubMed:32453425, PubMed:34694004, PubMed:34700328, PubMed:35585232), The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit, The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (PubMed:32453425), Required for the entry in S phase and for cell division (PubMed:8175912), Plays a role in terminally differentiated hair cells development of the cochlea and induces cells apoptosis (PubMed:26196677)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCM family", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLVAEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMILQQF", "length": 904, "molWeight": 101896, "crc64": "52C6DC61F128B404", "md5": "BB5D90539C536B36B294E50BDDD8A7B9"}}
{"primaryAccession": "P49739", "text": "This is Maternal DNA replication licensing factor mcm3 protein, from African clawed frog, contains 807 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P49739", "organism_name": "African clawed frog", "protein_name": "Maternal DNA replication licensing factor mcm3", "length": 807, "firstPublicDate": "1996-10-01", "FUNCTION": "Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells, The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit, The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity, The existence of maternal and zygotic forms of mcm3 and mcm6 suggests that specific forms of mcm2-7 complexes may be used during different stages of development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCM family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDYGGGFEDHELREAQREYLDFLDDDQDQGLYHGKVRDMIGSNEHRLIVNLNDVRRKNDKRANLMLNDAFAETIAFQRALKDLVASIDATYAKQFEEFSVGFEGSFGSKHVSPRTLTASLLGSLVCVEGIVTKCSLVRPKVMRSVHYCPATKKTLERKYSDLTSLEAFPSSSIYPTKDEENNPLETEYGLSTYKDHQTLSIQEMPEKAPAGQLPRSVDIIADDDLVDKCKPGDRVQIVGIYRCLPSKQGGFTSGTFRTILLANNIKLMSKEIAPTFSADDVAKIKKFCKAHSKDIFEHLSKSLAPSIHGHEYIKKAILCMLLGGNEKVLENGTRIRGDINVLLIGDPSVAKSQLLRYVLHTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIQARLNARCSVLAAANPVYGRYDQYRTPMENIGLQDSLLSRFDLLFIVLDKMDADNDQEIADHVLRMHRYRTPGEQDGYALPLGCSVEIFATDDPNASDVTDQELQIYEKHDNLLHGPRKNKSKIVSMQFIRKYIHVAKLIKPVLTSEAADYISQEYAKIRNHDQINNDSARTMPVTARALETMIRLSTAHAKVRMSKTIERQDAETALELVQFAYFKKVLAKEKKKTDKDLHDENLSQDTLSQESVRKSSRRAGKIADSQDDSMDPYSFSEQDSSLNENLSQSLRPQRKKAESQDGKRSLSQNRTKEFKAALLKAFKSSRSQSVAVSQLLELINKGNPEPFERSEVKEALDNMQNDNQVMVSEDVVFLI", "length": 807, "molWeight": 90405, "crc64": "70B08E9BE0F3A81F", "md5": "6D04AB585D911087A2EAC42568C5F6EB"}}
{"primaryAccession": "P49862", "text": "This is Kallikrein-7 protein, from Human, contains 253 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P49862", "organism_name": "Human", "protein_name": "Kallikrein-7", "length": 253, "firstPublicDate": "1996-10-01", "FUNCTION": "May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface, Specific for amino acid residues with aromatic side chains in the P1 position, Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27', Could play a role in the activation of precursors to inflammatory cytokines", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Kallikrein subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR", "length": 253, "molWeight": 27525, "crc64": "2D68B6B15A76A668", "md5": "DD703B2BF353DE81A9BEC582C65D6AB4"}}
{"primaryAccession": "P49866", "text": "This is Transcription factor HNF-4 homolog protein, from Fruit fly, contains 704 amino acids, has 2 NR C4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [142, 162], "description": "NR C4-type", "keyword_description": "Zinc finger", "textural_description": "NR C4-type Zinc finger"}, {"location": [178, 197], "description": "NR C4-type", "keyword_description": "Zinc finger", "textural_description": "NR C4-type Zinc finger"}], "meta_data": {"primaryAccession": "P49866", "organism_name": "Fruit fly", "protein_name": "Transcription factor HNF-4 homolog", "length": 704, "firstPublicDate": "1996-10-01", "FUNCTION": "Transcriptionally controlled transcription factor, Important for the differentiation of various specialized cell types that arise from both endoderm and mesoderm, May have a role in early gut formation, Plays an essential role in lipid catabolism, regulating lipid mobilization and beta-oxidation in response to nutrient deprivation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the nuclear hormone receptor family, NR2 subfamily", "domain_description": {"NR C4-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMKHPQDLSVTDDQQLMKVNKVEKMEQELHDPESESHIMHADALASAYPAASQPHSPIGLALSPNGGGLGLSNSSNQSSENFALCNGNGNAGSAGGGSASSGSNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLLGGELADNPLPLSPPNQSNDYQSPTHTGNMEGGNQVNSSLDSLATSGGPGSHSLDLEVQHIQALIEANSADDSFRAYAASTAAAAAAAVSSSSSAPASVAPASISPPLNSPKSQHQHQQHATHQQQQESSYLDMPVKHYNGSRSGPLPTQHSPQRMHPYQRAVASPVEVSSGGGGLGLRNPADITLNEYNRSEGSSAEELLRRTPLKIRAPEMLTAPAGYGTEPCRMTLKQEPETGY", "length": 704, "molWeight": 76388, "crc64": "5868280AFE7A00CC", "md5": "4B792316A0D5405CFC21BBAE4BD49CB0"}}
{"primaryAccession": "P50111", "text": "This is Protein ZDS1 protein, from Baker's yeast, contains 915 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P50111", "organism_name": "Baker's yeast", "protein_name": "Protein ZDS1", "length": 915, "firstPublicDate": "1996-10-01", "FUNCTION": "When associated with DBP5, GFD1 and nucleoporins at the cytosolic fibrils of the nuclear pore complex, is required for mRNA export form the nucleus", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "To yeast ZDS2/MCS1", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSNRDNESMLRTTSSDKAIASQRDKRKSEVLIAAQSLDNEIRSVKNLKRLSIGSMDLLIDPELDIKFGGESSGRRSWSGTTSSSASMPSDTTTVNNTRYSDPTPLENLHGRGNSGIESSNKTKQGNYLGIKKGVHSPSRKLNANVLKKNLLWVPANQHPNVKPDNFLELVQDTLQNIQLSDNGEDNDGNSNENNDIEDNGEDKESQSYENKENNTINLNRGLSRHGNASLIRRPSTLRRSYTEFDDNEDDDNKGDSASETVNKVEERISKIKERPVSLRDITEELTKISNSAGLTDNDAITLARTLSMAGSYSDKKDQPQPEGHYDEGDIGFSTSQANTLDDGEFASNMPINNTMTWPERSSLRRSRFNTYRIRSQEQEKEVEQSVDEMKNDDEERLKLTKNTIKVEIDPHKSPFRQQDEDSENMSSPGSIGDFQDIYNHYRQSSGEWEQEMGIEKEAEEVPVKVRNDTVEQDLELREGTTDMVKPSATDDNKETKRHRRRNGWTWLNNKMSREDDNEENQGDDENEENVDSQRMELDNSKKHYISLFNGGEKTEVSNKEEMNNSSTSTATSQTRQKIEKTFANLFRRKPHHKHDASSSPSSSPSSSPSIPNNDAVHVRVRKSKKLGNKSGREPVEPIVLRNRPRPHRHHHSRHGSQKISVKTLKDSQPQQQIPLQPQLEGAIEIEKKEESDSESLPQLQPAVSVSSTKSNSRDREEEEAKKKNKKRSNTTEISNQQHSKHVQKENTDEQKAQLQAPAQEQVQTSVPVQASAPVQNSAPVQTSAPVEASAQTQAPAAPPLKHTSILPPRKLTFADVKKPDKPNSPVQFTDSAFGFPLPLLTVSTVIMFDHRLPINVERAIYRLSHLKLSNSKRGLREQVLLSNFMYAYLNLVNHTLYMEQVAHDKEQQQQQQQQP", "length": 915, "molWeight": 103358, "crc64": "E5F4C2117DBE1210", "md5": "B42BB8C63611786CDB209AD8380BB1A4"}}
{"primaryAccession": "P50133", "text": "This is Parathyroid hormone/parathyroid hormone-related peptide receptor protein, from Pig, contains 585 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P50133", "organism_name": "Pig", "protein_name": "Parathyroid hormone/parathyroid hormone-related peptide receptor", "length": 585, "firstPublicDate": "1996-10-01", "FUNCTION": "Receptor for parathyroid hormone and for parathyroid hormone-related peptide, The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGAARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPADIMESDKGWASAPTSGKPRKEKASGKLYPESGEDTGSRHQGRPCLPEWDHILCWPLGAPGEVVAMPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPLPPVAATSYVGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAIFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRTGLGLPLSPRLLPAATTNGHPQLPCHTKPETPALQTTPPVVAAPKDDGFLNGSCSGLDEEASAPERPSVLLQEEWETVM", "length": 585, "molWeight": 65682, "crc64": "60BE15CD49B7D210", "md5": "6A506F1AF7793138CB983E120DB3C1B4"}}
{"primaryAccession": "P50402", "text": "This is Emerin protein, from Human, contains 254 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P50402", "organism_name": "Human", "protein_name": "Emerin", "length": 254, "firstPublicDate": "1996-10-01", "FUNCTION": "Stabilizes and promotes the formation of a nuclear actin cortical network, Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments, Inhibits beta-catenin activity by preventing its accumulation in the nucleus, Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway, Links centrosomes to the nuclear envelope via a microtubule association, Required for proper localization of non-farnesylated prelamin-A/C, Together with NEMP1, contributes to nuclear envelope stiffness in germ cells (PubMed:32923640), EMD and BAF are cooperative cofactors of HIV-1 infection, Association of EMD with the viral DNA requires the presence of BAF and viral integrase, The association of viral DNA with chromatin requires the presence of BAF and EMD", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRLSPPSSSAASSYSFSDLNSTRGDADMYDLPKKEDALLYQSKGYNDDYYEESYFTTRTYGEPESAGPSRAVRQSVTSFPDADAFHHQVHDDDLLSSSEEECKDRERPMYGRDSAYQSITHYRPVSASRSSLDLSYYPTSSSTSFMSSSSSSSSWLTRRAIRPENRAPGAGLGQDRQVPLWGQLLLFLVFVIVLFFIYHFMQAEEGNPF", "length": 254, "molWeight": 28994, "crc64": "EB62EDD59B7A044F", "md5": "D813C5ABC1D2E9BBA4500094A14BE4CB"}}
{"primaryAccession": "P50536", "text": "This is Protein male-specific lethal-3 protein, from Fruit fly, contains 512 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P50536", "organism_name": "Fruit fly", "protein_name": "Protein male-specific lethal-3", "length": 512, "firstPublicDate": "1996-10-01", "FUNCTION": "The MSL proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation), Mle, msl-1 and msl-3 are colocalized on the X chromosome, Each of the MSL proteins requires all the other MSLs for wild-type X-chromosome binding", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTELRDETPLFHKGEIVLCYEPDKSKARVLYTSKVLNVFERRNEHGLRFYEYKIHFQGWRPSYDRCVRATVLLKDTEENRQLQRELAEAAKLQIRGDYSYKGTPDKPSAKKKRGGKAAHVEEPIVVPMDTGHLEAEHEMAPTPRAAGNRTRDNSGGKRKEKPPSGDGRLKGNRGRQTETFYNNAINDVSVYNHVPQEDRIMMRVSERLRELIEYDRNMIKVLGKQHALPARVPIVTIMENFVKQQAVELAISIKQDSSRARNTQSRNARMEREYDRVMSTVCMLKEVVDGLRIYFEFHVDDHLLYTEEKEYVHNYLTDDNMRNCSLILNKSYEYINPSGDTELIGLDGTPVVEGSGDTNGQIGVINIGGPEYEKQLQKCLLYIVTASGKNTAQAYERTSPYTAAYKLPVEMRGFLNETFKWRLLSAESPPEKSMVFGAPHLVRLMIKMPMFLNASPISNKKLEDLLPHLDAFINYLENHREWFDRENFVNSTALPQEDLQRELLDSLDGIAA", "length": 512, "molWeight": 58853, "crc64": "3101BC92B2339991", "md5": "11E636F238A6408EEC6E776A9168E651"}}
{"primaryAccession": "P50582", "text": "This is Cell cycle serine/threonine-protein kinase hsk1 protein, from Fission yeast, contains 507 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P50582", "organism_name": "Fission yeast", "protein_name": "Cell cycle serine/threonine-protein kinase hsk1", "length": 507, "firstPublicDate": "1996-10-01", "FUNCTION": "Required for G1/S transition, Plays a role in DNA replication checkpoint signaling through regulating rad3 and cds1, Involved in the maintenance of mitotic chromosome structures during S phase through regulating the function of rad21, Required for initiation of mitotic DNA replication through phosphorylating mcm2/cdc19, Required for genome integrity", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAEAHITLSPKVTHEQQTDIDSECEITEVDDENVNENKSQEMIQDIPARDREEIENITRTFVELQENYRLIEKIGEGTFSSVYKAEDLHYGRYINDWDIQSEVLKESSFGKEKIPVNEDSRKPKYVAIKKIYATSSPARIYNELEILYLLRGSSVIAPLITALRNEDQVLVVLPYYEHTDFRQYYSTFSYRDMSIYFRCLFQAMQQTQTLGIIHRDIKPSNFLFDVRTKHGVLVDFGLAERYDGRQQSHSCRCTNSNAAELAHDFSIAQETSLGYIKNDTRPSKRANRAGTRGFRAPEVLFKCSSQSPKVDIWSAGVILLSFLTKRFPMFNSKDDVDALMEIACIFGKSEMRQCAALHGCTFETNVSTLTEKRVNFRKLILWASCGSASIYKEKLRHKPSQEERLCLDFLEKCLELDCNKRISAEEALDHDFLYLDNLAYEKKDDDTAFDNSFGETSFEKDEDLTAKHLSHILDFKEQEETDEPTSLSKRKRSIDEILPNDALQDGA", "length": 507, "molWeight": 58408, "crc64": "04970E58218441EE", "md5": "995EF1EE890690CCA335E9542DF7BE00"}}
{"primaryAccession": "P51402", "text": "This is Large ribosomal subunit protein eL37B protein, from Baker's yeast, contains 88 amino acids, has 1 C4-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [19, 37], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "P51402", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein eL37B", "length": 88, "firstPublicDate": "1996-10-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eL37 family", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPSAKTRSHNWAAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSAKATSA", "length": 88, "molWeight": 9868, "crc64": "A9276219D26BE008", "md5": "94CAB4704A2FCC84B4272C59992ADE37"}}
{"primaryAccession": "P51553", "text": "This is Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial protein, from Human, contains 393 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P51553", "organism_name": "Human", "protein_name": "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "length": 393, "firstPublicDate": "1996-10-01", "FUNCTION": "Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate, The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA", "length": 393, "molWeight": 42794, "crc64": "A0870F2B7D228A37", "md5": "F3971E481E06398362F487F63B03FE94"}}
{"primaryAccession": "P51813", "text": "This is Cytoplasmic tyrosine-protein kinase BMX protein, from Human, contains 675 amino acids, has 1 Btk-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [113, 149], "description": "Btk-type", "keyword_description": "Zinc finger", "textural_description": "Btk-type Zinc finger"}], "meta_data": {"primaryAccession": "P51813", "organism_name": "Human", "protein_name": "Cytoplasmic tyrosine-protein kinase BMX", "length": 675, "firstPublicDate": "1996-10-01", "FUNCTION": "Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis, Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins, Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation, Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility, Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis, Required for the phosphorylation and activation of STAT3, a transcription factor involved in cell differentiation, Also involved in interleukin-6 (IL6) induced differentiation, Also plays a role in programming adaptive cytoprotection against extracellular stress in different cell systems, salivary epithelial cells, brain endothelial cells, and dermal fibroblasts, May be involved in regulation of endocytosis through its interaction with an endosomal protein RUFY1, May also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, Tyr protein kinase family, TEC subfamily", "domain_description": {"Btk-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSIEIKKIRCVEKVNLEEQTPVERQYPFQIVYKDGLLYVYASNEESRSQWLKALQKEIRGNPHLLVKYHSGFFVDGKFLCCQQSCKAAPGCTLWEAYANLHTAVNEEKHRVPTFPDRVLKIPRAVPVLKMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDFPDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFPESSSSEEEENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREKDKH", "length": 675, "molWeight": 78011, "crc64": "CB22382A3BD02599", "md5": "9C91E351DEF88DA35F1A3E60C94DFB6B"}}
{"primaryAccession": "P52188", "text": "This is ATP-sensitive inward rectifier potassium channel 12 protein, from Rat, contains 427 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P52188", "organism_name": "Rat", "protein_name": "ATP-sensitive inward rectifier potassium channel 12", "length": 427, "firstPublicDate": "1996-10-01", "FUNCTION": "Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells, Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues, Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it, Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages, The inward rectification is mainly due to the blockage of outward current by internal magnesium", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the inward rectifier-type potassium channel (TC 1,A,2,1) family, KCNJ12 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTAASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVLQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMGRPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLLPSANSFCYENELAFLSRDEEDEVATDRDGRSPQPEHDFDRLQASSGALERPYRRESEI", "length": 427, "molWeight": 48399, "crc64": "6FA100FEB6066677", "md5": "916147265FB6EEDFAB51F2D246180E3A"}}
{"primaryAccession": "P52848", "text": "This is Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 protein, from Human, contains 882 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P52848", "organism_name": "Human", "protein_name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1", "length": 882, "firstPublicDate": "1996-10-01", "FUNCTION": "Lacks both N-deacetylase and N-sulfotransferase activities, Acts as a dominant negative on isoform 1, likely by changing the composition of enzyme complexes responsible for elongation and modification of heparan sulfates", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the sulfotransferase 1 family, NDST subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPALACLRRLCRHVSPQAVLFLLFIFCLFSVFISAYYLYGWKRGLEPSADAPEPDCGDPPPVAPSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGKFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNTR", "length": 882, "molWeight": 100868, "crc64": "D4B716B84A0BF4C4", "md5": "0E2CC39217DD73B1599200E054072225"}}
{"primaryAccession": "P53063", "text": "This is Decapping nuclease RAI1 protein, from Baker's yeast, contains 387 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53063", "organism_name": "Baker's yeast", "protein_name": "Decapping nuclease RAI1", "length": 387, "firstPublicDate": "1996-10-01", "FUNCTION": "Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity), The NAD-cap is present at the 5'-end of some RNAs and snoRNAs, In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity), Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (PubMed:12897126, PubMed:20802481, PubMed:26101253), Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (PubMed:12897126, PubMed:20802481), Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5'-end triphosphate to release pyrophosphates (PubMed:20802481), Stimulates exoribonuclease activity of RAT1, allowing it to degrade RNAs with stable secondary structure more effectively (PubMed:20802481), Required for the processing of nuclear mRNA and rRNA precursors (PubMed:10805743, PubMed:12612077, PubMed:16131592), May promote termination of transcription by RNA polymerase II (PubMed:15565157)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the DXO/Dom3Z family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGVSANLFVKQRGSTTALKQPKEIGFYSRTKDEEYLISDDTNLNYYYLPDAELDRKLDLSSGFQKFKDYYKDFEDRCSLRGLLETIESSERHKGKKINADIITFRGIARKLISCAFDSPSFNTVDLRIVSFNGQLFIKEVPEAVNAAKASSATEAGRNINQDLNVFTGYKFETLATLSNPLQYTPREVIEKRTKRIVSHGDEYISVVRTGVGNCKLILGAEVDCIFDFKENGRDNLKHYAELKCTQQVANISDTHKFERKLFRTWLQCFLVGIPRIIYGFKDDHYVLKTVEEFSTEEVPVLLKNNNPQVGSACLEAIKWYGLLTEWLLKMIPRDEDPHSQIRAFKLVFENNHLRLSEIEESDEEYSGLIDGEHILSNGFKEWRKSLK", "length": 387, "molWeight": 44510, "crc64": "E4A6565AF690A3E1", "md5": "C8453DBCA43854AB81321AD768AD691E"}}
{"primaryAccession": "P53083", "text": "This is Mitochondrial distribution and morphology protein 34 protein, from Baker's yeast, contains 459 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53083", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial distribution and morphology protein 34", "length": 459, "firstPublicDate": "1996-10-01", "FUNCTION": "Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria (PubMed:11907266, PubMed:14981098), Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria (PubMed:27469264), MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10 (By similarity) (PubMed:19556461)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MDM34 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSFRFNEAVFGDNSFNERIREKLSTALNSPSKKKLDILKSGIKVQKVDFPTIPQLEILDLDIITQPKSLAKGICKISCKDAMLRIQTVIESNLLLINEQDTPSFTMPQLINNGSFTIPITMTFSSIELEAITNIFVKNPGIGISFNDVDLDFKFDCSVKILQSTIERRLKESMHVVFKDVLPSLIFNTSQNWFTNRGESTSTIPGKREHHHQQTTMSRNVILDGSDFQELSPINMLRLSSIVSSRSTLSLHSTVMNSLSAIPGCLERQNLYRFISRMPSLNNYYSSQSFPQPKSSTVSSKQLVKPFYCSHNLLPKTVLDSSQYDLATITKIQSRLFDRSNSNDDNAKPRRRKIKCKKTRTPSNLQSQGEQAVDDSTAIETVTSTPVQTPIPELEEQSPPYLKTTVSIRDKYVIPEKISLNLDSKKDTSKKKPFYFIGLNSQEPSNNWKWGMEDSPPPYH", "length": 459, "molWeight": 51990, "crc64": "222F0D0D031FC578", "md5": "27391619EF8D6F00E01B72141AB48631"}}
{"primaryAccession": "P53093", "text": "This is Protein YIP4 protein, from Baker's yeast, contains 235 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53093", "organism_name": "Baker's yeast", "protein_name": "Protein YIP4", "length": 235, "firstPublicDate": "1996-10-01", "FUNCTION": "May be involved in proper membrane localization of Rab GTPases", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the YIP1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSYGREDTTIEPDFIEPDAPLAASGGVADNIGGTMQNSGSRGTLDETVLQTLKRDVVEINSRLKQVVYPHFPSFFSPSDDGIGAADNDISANCDLWAPLAFIILYSLFVSHARSLFSSLFVSSWFILLVMALHLRLTKPHQRVSLISYISISGYCLFPQVLNALVSQILLPLAYHIGKQNRWIVRVLSLVKLVVMALCLMWSVAAVSWVTKSKTIIEIYPLALCLFGMAWLSTIL", "length": 235, "molWeight": 25995, "crc64": "642B53FDCCDEA86A", "md5": "7263F9FDC9FDD444C7C1C336063D27E5"}}
{"primaryAccession": "P53178", "text": "This is UDP-N-acetylglucosamine transferase subunit ALG13 protein, from Baker's yeast, contains 202 amino acids, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53178", "organism_name": "Baker's yeast", "protein_name": "UDP-N-acetylglucosamine transferase subunit ALG13", "length": 202, "firstPublicDate": "1996-10-01", "FUNCTION": "Involved in protein N-glycosylation, Essential for the second step of the dolichol-linked oligosaccharide pathway", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyltransferase 28 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGIIEEKALFVTCGATVPFPKLVSCVLSDEFCQELIQYGFVRLIIQFGRNYSSEFEHLVQERGGQRESQKIPIDQFGCGDTARQYVLMNGKLKVIGFDFSTKMQSIIRDYSDLVISHAGTGSILDSLRLNKPLIVCVNDSLMDNHQQQIADKFVELGYVWSCAPTETGLIAGLRASQTEKLKPFPVSHNPSFERLLVETIYS", "length": 202, "molWeight": 22661, "crc64": "9D5CDB366BBC1ED0", "md5": "0C506279A90732979A0CC72BD7E92678"}}
{"primaryAccession": "P53193", "text": "This is J-type co-chaperone JAC1, mitochondrial protein, from Baker's yeast, contains 184 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53193", "organism_name": "Baker's yeast", "protein_name": "J-type co-chaperone JAC1, mitochondrial", "length": 184, "firstPublicDate": "1996-10-01", "FUNCTION": "Co-chaperone required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria, Stimulates the ATPase activity of its specialized Hsp70 chaperone partner SSQ1, to mediate the transfer of iron-sulfur clusters from ISU1 to GRX5, Binds to the substrate protein ISU1 and targets it to SSQ1", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the HscB family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLKYLVQRRFTSTFYELFPKTFPKKLPIWTIDQSRLRKEYRQLQAQHHPDMAQQGSEQSSTLNQAYHTLKDPLRRSQYMLKLLRNIDLTQEQTSNEVTTSDPQLLLKVLDIHDELSQMDDEAGVKLLEKQNKERIQDIEAQLGQCYNDKDYAAAVKLTVELKYWYNLAKAFKDWAPGKQLEMNH", "length": 184, "molWeight": 21778, "crc64": "92B600F279866DF9", "md5": "9B6CAD83BDE2DC28FF9B773E0B9ECBCA"}}
{"primaryAccession": "P53199", "text": "This is Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating protein, from Baker's yeast, contains 349 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53199", "organism_name": "Baker's yeast", "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating", "length": 349, "firstPublicDate": "1996-10-01", "FUNCTION": "Sterol-4-alpha-carboxylate 3-dehydrogenase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (PubMed:9811880, PubMed:15995173), ERG26 is a catalytic component of the C-4 demethylation complex that catalyzes the oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group (PubMed:9811880), The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane, Firstly, the squalene synthase ERG9 catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids, Squalene synthase is crucial for balancing the incorporation of farnesyl diphosphate (FPP) into sterol and nonsterol isoprene synthesis, Secondly, the squalene epoxidase ERG1 catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, which is considered to be a rate-limiting enzyme in steroid biosynthesis, Then, the lanosterol synthase ERG7 catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol core, In the next steps, lanosterol is transformed to zymosterol through a complex process involving various demethylation, reduction and desaturation reactions, The lanosterol 14-alpha-demethylase ERG11 (also known as CYP51) catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol, which is critical for ergosterol biosynthesis, The C-14 reductase ERG24 reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol, 4,4-dimethyl-cholesta-8,24-dienol is substrate of the C-4 demethylation complex ERG25-ERG26-ERG27 in which ERG25 catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, ERG26 catalyzes the oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group, and ERG27 is responsible for the reduction of the keto group on the C-3, ERG28 has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum and ERG29 regulates the activity of the iron-containing C4-methylsterol oxidase ERG25, Then, the sterol 24-C-methyltransferase ERG6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol, The C-8 sterol isomerase ERG2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol, The sterol-C5-desaturase ERG3 then catalyzes the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol, The C-22 sterol desaturase ERG5 further converts 5-dehydroepisterol into ergosta-5,7,22,24(28)-tetraen-3beta-ol by forming the C-22(23) double bond in the sterol side chain, Finally, ergosta-5,7,22,24(28)-tetraen-3beta-ol is substrate of the C-24(28) sterol reductase ERG4 to produce ergosterol (PubMed:32679672)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the 3-beta-HSD family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSKIDSVLIIGGSGFLGLHLIQQFFDINPKPDIHIFDVRDLPEKLSKQFTFNVDDIKFHKGDLTSPDDMENAINESKANVVVHCASPMHGQNPDIYDIVNVKGTRNVIDMCKKCGVNILVYTSSAGVIFNGQDVHNADETWPIPEVPMDAYNETKAIAEDMVLKANDPSSDFYTVALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLDPKTRTAVSGETFFITNDTPTYFWALARTVWKADGHIDKHVIVLKRPVAICAGYLSEWVSKMLGKEPGLTPFRVKIVCAYRYHNIAKAKKLLGYTPRVGIEEGINKTLAWMDEGL", "length": 349, "molWeight": 38706, "crc64": "87CA8FF8D64B0327", "md5": "027B011DC729B578545A0981E99004B2"}}
{"primaryAccession": "P53223", "text": "This is Dolichyldiphosphatase protein, from Baker's yeast, contains 239 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53223", "organism_name": "Baker's yeast", "protein_name": "Dolichyldiphosphatase", "length": 239, "firstPublicDate": "1996-10-01", "FUNCTION": "Non-essential protein which is required for efficient N-glycosylation, Necessary for maintaining optimal levels of dolichol-linked oligosaccharides, Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate, Does not act on phosphatidate", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the dolichyldiphosphatase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNSTAAAINPNPNVIPFDDTYILYDSHDFLSFLSAYFSLMPILVLAFYLSWFIITRELEACIVAFGQLMNEIFNNVIKNIIKQPRPVSFGASFQNDTIRSGYGMPSAHSQFMGFCFTYNSLKIYTSWKNLNFLEKCIFSGALALLSFCVCFSRVYLHYHNLDQVIVGFSVGALTGSLYFFIVGIIRELGLINWFLKLRIVRLFYMTDSYNLAPLTLKENYEAYWKRINQRSFNDKSKRD", "length": 239, "molWeight": 27649, "crc64": "C8EC49CBFC08F8F8", "md5": "FD3221E568140728BE03A64791583C68"}}
{"primaryAccession": "P53236", "text": "This is Chromatin structure-remodeling complex subunit RSC1 protein, from Baker's yeast, contains 928 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53236", "organism_name": "Baker's yeast", "protein_name": "Chromatin structure-remodeling complex subunit RSC1", "length": 928, "firstPublicDate": "1996-10-01", "FUNCTION": "Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning, RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA, The reaction requires ATP and involves an activated RSC-nucleosome intermediate, Remodeling reaction also involves DNA translocation, DNA twist and conformational change, As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton, This subunit is involved in meiotic sporulation through regulating IME2 expression", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RSC1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVEQDNGFLQKLLKTQYDAVFHLKDENGIEIYPIFNVLPPKKEYPDYYIIIRNPISLNTLKKRLPHYTSPQDFVNDFAQIPWNAMTYNAKDSVIYKYAILLESFIKGKIVHNIRKHYPEVTYPSLGRIPEIFAESMQPSDLSSNPINTQENDEKAGLNPEMKMAFAKLDSSITERKPTNQDYRMQQKNSPAFPTHSASITPQPLASPTPVVNYANITSAHPKTHVRRGRPPVIDLPYVLRIKNILKMMRREVDQNNKTLTLCFEKLPDRNEEPTYYSVITDPICLMDIRKKVKSRKYRNFHTFEEDFQLMLTNFKLYYSQDQSNIIRAQLLEKNFNRLVRIELSKPDEDYLPEGELRYPLDDVEINDEKYQIGDWVLLHNPNDINKPIVGQIFRLWSTTDGNKWLNACWYFRPEQTVHRVDRLFYKNEVMKTGQYRDHPIQDIKGKCYVIHFTRFQRGDPSTKVNGPQFVCEFRYNESDKVFNKIRTWKACLPEELRDQDEPTIPVNGRKFFKYPSPIADLLPANATLNDKVPEPTEGAPTAPPLVGAVYLGPKLERDDLGEYSTSDDCPRYIIRPNDPPEEGKIDYETGTIITDTLTTSSMPRVNSSSTIRLPTLKQTKSIPSSNFRSSSNTPLLHQNFNQTSNFLKLENMNNSSHNLLSHPSVPKFQSPSLLEQSSRSKYHSAKKQTQLSSTAPKKPASKSFTLSSMINTLTAHTSKYNFNHIVIEAPGAFVVPVPMEKNIRTIQSTERFSRSNLKNAQNLGNTAINDINTANEQIIWFKGPGVKITERVIDSGNDLVRVPLNRWFCKNKRRKLDYEDIEEDVMEPPNDFSEDMIANIFNPPPSLNLDMDLNLSPSSNNSSNFMDLSTIASGDNDGKECDTAEESEDENEDTEDEHEIEDIPTTSAFGLNSSAEYLAFRLREFNKL", "length": 928, "molWeight": 106669, "crc64": "EFF80922FC08EC27", "md5": "831E71B26B62CDE8B73677F80F42596B"}}
{"primaryAccession": "P53259", "text": "This is Rhomboid protein 1, mitochondrial protein, from Baker's yeast, contains 346 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53259", "organism_name": "Baker's yeast", "protein_name": "Rhomboid protein 1, mitochondrial", "length": 346, "firstPublicDate": "1996-10-01", "FUNCTION": "Mitochondrial rhomboid serine protease processing the mitochondrial membrane fusion regulator MGM1, and the cytochrome c peroxidase (CCP1), Required for TIM11 stability, ATP synthase complex assembly, mitochondrial morphology, cytochrome c (CYC1) storage and mitochondrial genome maintenance", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the peptidase S54 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSGVSSVMLGLRPATRIFFRSNISVSPSRTFVSYIGRSQSTSILKNAPNLEDNVTNLQKIIPKRFFSQTSILKSRWKPIFNEETTNRYVRLNRFQQYQQQRSGGNPLGSMTILGLSLMAGIYFGSPYLFEHVPPFTYFKTHPKNLVYALLGINVAVFGLWQLPKCWRFLQKYMLLQKDYVTSKISIIGSAFSHQEFWHLGMNMLALWSFGTSLATMLGASNFFSLYMNSAIAGSLFSLWYPKLARLAIVGPSLGASGALFGVLGCFSYLFPHAKILLFVFPVPGGAWVAFLASVAWNAAGCALRWGSFDYAAHLGGSMMGVLYGWYISKAVEKQRQRRLQAAGRWF", "length": 346, "molWeight": 38815, "crc64": "692AC44C043C9A28", "md5": "98DF7F32B347A4EBC1FFFBEC3F4881A8"}}
{"primaryAccession": "P53298", "text": "This is Inner kinetochore subunit OKP1 protein, from Baker's yeast, contains 406 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53298", "organism_name": "Baker's yeast", "protein_name": "Inner kinetochore subunit OKP1", "length": 406, "firstPublicDate": "1996-10-01", "FUNCTION": "Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis, Component of the inner kinetochore COMA complex, which connects centromere-associated proteins and the outer kinetochore, COMA interacts with other inner kinetochore proteins to form the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CENP-Q/OKP1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAADRDNFLQNIENDSINNGQAMDLSPNRSSSESDSSILMNVNDIKTLRLDVAPEAKSTQSKKSLFYENSDDAEEGEIEERTNKEEGQYHHKGSKQLRFEVGKESTGKLQSHLSDGSATSGEGNVRPWEFRKVIQAEYRERLPRNYELKHWKKPSKIMIGSILRLLETNTVSALDSVFEKYEKEMNQMTHGDNNEVKRIYSKKERLLEIILTKIKKKLRQAKFPSRISERDLDIEYIYSKRQFIQNRYSQELQNNERLEAILSREQNLLEETRKLCMNLKTNNKKRLTEKLIQKDLHPVLNKAMEYTYGLESTNGFMHPDGPVTFRNDSHELNLMLNDPIKSTADVRLDKEEVLSLLPSLKEYTKKSKELKETMGQMISDSHEEEIKEVFVPHHESHQDKTEEDIH", "length": 406, "molWeight": 47349, "crc64": "F664346B37EEFFF5", "md5": "7645B159E856522FC2B3700285C41E14"}}
{"primaryAccession": "P53311", "text": "This is Mitochondrial pyruvate carrier 3 protein, from Baker's yeast, contains 146 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53311", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial pyruvate carrier 3", "length": 146, "firstPublicDate": "1996-10-01", "FUNCTION": "Mediates the uptake of pyruvate into mitochondria", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2,A,105) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSASAFNFAFRRFWNSETGPKTVHFWAPTLKWGLVFAGLNDIKRPVEKVSGAQNLSLLATALIWTRWSFVIKPKNYLLASVNFFLGCTAGYHLTRIANFRIRNGDSFKQVIHYIIKGETPAAVAAKQTASTSMNKGVIGTNPPITH", "length": 146, "molWeight": 16230, "crc64": "E0B13933AB142B4E", "md5": "A31BDC622660FFAF7C13AB935C35BF05"}}
{"primaryAccession": "P53314", "text": "This is 2',3'-cyclic-nucleotide 3'-phosphodiesterase protein, from Baker's yeast, contains 239 amino acids, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53314", "organism_name": "Baker's yeast", "protein_name": "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "length": 239, "firstPublicDate": "1996-10-01", "FUNCTION": "Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the 2H phosphoesterase superfamily, CPD1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAIALWYCPPQGSVAYETLQMLIFSFQTLFPDSPVFEPHVTVTSHLVCNSKDDVNKILTSCVAAIQSIRSHQTAKKGRKGQVSHAVAAPLVSFNGCSVGKQYFKKIVLECNKNKILYGVAQVMREMYVEIDPETRSSRAATWVHEEFHPHVSLLYSDIHPVSQASLRVVQQRIEDALDVQLVPREKRKGSGNADGSNEVQMRWDFDVSSSLSWNIPGTFKVVNCVGPVQEWEVLGRVDV", "length": 239, "molWeight": 26732, "crc64": "DE38A74FAD0E3A55", "md5": "4888C37D0965FE52578D1500095BC4CF"}}
{"primaryAccession": "P53318", "text": "This is Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial protein, from Baker's yeast, contains 479 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53318", "organism_name": "Baker's yeast", "protein_name": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "length": 479, "firstPublicDate": "1996-10-01", "FUNCTION": "FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis, Catalyzes the hydroxylation of 3-hexaprenyl-4-hydroxybenzoic acid (HHB) to 3-hexaprenyl-4,5-dihydroxybenzoic acid (DHHB), The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via ferredoxin (YAH1) and ferredoxin reductase (ARH1) to COQ6 (PubMed:21944752), Can also convert 3-hexaprenyl-4-aminobenzoic acid (HAB), a COQ2-prenylated pABA, to DHHB in a two step process, HAB is first hydroxylated at C5 to yield 3-hexaprenyl-4-amino-5-hydroxybenzoic acid (HHAB) which is further deaminated at C4 by COQ6 to produce DHHB (PubMed:26260787)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the UbiH/COQ6 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFFSKVMLTRRILVRGLATAKSSAPKLTDVLIVGGGPAGLTLAASIKNSPQLKDLKTTLVDMVDLKDKLSDFYNSPPDYFTNRIVSVTPRSIHFLENNAGATLMHDRIQSYDGLYVTDGCSKATLDLARDSMLCMIEIINIQASLYNRISQYDSKKDSIDIIDNTKVVNIKHSDPNDPLSWPLVTLSNGEVYKTRLLVGADGFNSPTRRFSQIPSRGWMYNAYGVVASMKLEYPPFKLRGWQRFLPTGPIAHLPMPENNATLVWSSSERLSRLLLSLPPESFTALINAAFVLEDADMNYYYRTLEDGSMDTDKLIEDIKFRTEEIYATLKDESDIDEIYPPRVVSIIDKTRARFPLKLTHADRYCTDRVALVGDAAHTTHPLAGQGLNMGQTDVHGLVYALEKAMERGLDIGSSLSLEPFWAERYPSNNVLLGMADKLFKLYHTNFPPVVALRTFGLNLTNKIGPVKNMIIDTLGGNEK", "length": 479, "molWeight": 53527, "crc64": "B6D4286545CCE695", "md5": "6438427BD5C8E5A6096C75A314AE5F29"}}
{"primaryAccession": "P53330", "text": "This is Regulator of Ty1 transposition protein 102 protein, from Baker's yeast, contains 157 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53330", "organism_name": "Baker's yeast", "protein_name": "Regulator of Ty1 transposition protein 102", "length": 157, "firstPublicDate": "1996-10-01", "FUNCTION": "Probable component of the chromatin structure-remodeling complex (RSC) which is involved in transcription regulation and nucleosome positioning, RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA, The reaction requires ATP and involves an activated RSC-nucleosome intermediate, Remodeling reaction also involves DNA translocation, DNA twist and conformational change, As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton, Probable component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, is required for the positive and negative regulation of gene expression of a large number of genes, It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDPQTLITKANKVSYYGNPTSKESWRYDWYQPSKVSSNVQQPQQQLGDMENNLEKYPFRYKTWLRNQEDEKNLQRESCEDILDLKEFDRRILKKSLMTSHTKGDTSKATGAPSANQGDEALSVDDIRGAVGNSEAIPGLSAGVNNDNTKESKDVKMN", "length": 157, "molWeight": 17795, "crc64": "D71CA1234D0D0176", "md5": "9FC303B3E9FD34F52DA88D0F8B7EE57C"}}
{"primaryAccession": "P53721", "text": "This is Respiratory supercomplex factor 2, mitochondrial protein, from Baker's yeast, contains 224 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53721", "organism_name": "Baker's yeast", "protein_name": "Respiratory supercomplex factor 2, mitochondrial", "length": 224, "firstPublicDate": "1996-10-01", "FUNCTION": "Assembly factor that plays a role in the assembly of the respiratory chain supercomplexes (SCs) composed of ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), May be required for late-stage assembly of the COX12 and COX13 subunits (PubMed:22342701, PubMed:22310663), Required for the generation and maintenance of a normal proton motive force (PMF) across the inner mitochondrial membrane (IMM) by preventing proton leakage through an inactive population of CIV that accumulates when RCF1 and/or RCF2 proteins are absent (PubMed:30683696, PubMed:31591265)", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKILTQDEIEAHRSHTLKGGIEGALAGFAISAIIFKVLPRRYPKFKPSTLTWSIKTALWITPPTVLTAICAEEASNNFDATMYGSGSSSEDALDEHRRWKSLSTKDKFVEGLSNNKYKIITGAWAASLYGSWVIVNKDPIMTKAQKIVQARMYAQFITVGLLLASVGLSMYENKLHPNKQKVNEMRRWENALRVAEEEERLEKEGRRTGYVSNEERINSKIFKS", "length": 224, "molWeight": 25344, "crc64": "FA2C528A008CFE7C", "md5": "7ECDAA8022BB4B7FBA9F74862DC01309"}}
{"primaryAccession": "P53725", "text": "This is M-phase phosphoprotein 6 homolog protein, from Baker's yeast, contains 186 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53725", "organism_name": "Baker's yeast", "protein_name": "M-phase phosphoprotein 6 homolog", "length": 186, "firstPublicDate": "1996-10-01", "FUNCTION": "Involved in surveillance of pre-rRNAs and pre-mRNAs, and the degradation of cryptic non-coding RNAs (ncRNA) derived from intergenic regions and the ribosomal DNA spacer heterochromatin, Binds RNA", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSANNGVTGKLSSRVMNMKFMKFGKTDDEESSNSNTPSNINSDVEPIEQKGKLFGLDDSAWDLNSYKDDLKKISGKEKKKVKRVVYKKRPNLIISNVGYSELRKPEGVISGRKTFGDNSDDSGSRKRKFDEGEQNEDEKRDAKDKEFTGSQDDGEDEYDLDKLFKDSIKKKKTNHNGKNKNRNSKK", "length": 186, "molWeight": 21142, "crc64": "B1DEE530E6F9379C", "md5": "C0A442BBD9C9C56C8F7BDA386091AD06"}}
{"primaryAccession": "P53833", "text": "This is Ribonucleases P/MRP protein subunit POP3 protein, from Baker's yeast, contains 195 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53833", "organism_name": "Baker's yeast", "protein_name": "Ribonucleases P/MRP protein subunit POP3", "length": 195, "firstPublicDate": "1996-10-01", "FUNCTION": "Required for processing of 5,8S rRNA (short form) at site A3 and for 5'- and 3'-processing of pre-tRNA", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the POP3 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGSLKSLDKKIAKRRQVYKPVLDNPFTNEAHMWPRVHDQPLIWQLLQSSIINKLIHIQSKENYPWELYTDFNEIVQYLSGAHGNSDPVCLFVCNKDPDVPLVLLQQIPLLCYMAPMTVKLVQLPKSAMDTFKSVSKYGMLLLRCDDRVDKKFVSQIQKNVDLLQFPWLNAIKYRPTSVKLLKTTVPIVSKKRQK", "length": 195, "molWeight": 22612, "crc64": "5091EE590BDBCBEA", "md5": "F7A1AA08DF5BC2D45F028444B208D1C8"}}
{"primaryAccession": "P53865", "text": "This is Chaotic nuclear migration protein 67 protein, from Baker's yeast, contains 581 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53865", "organism_name": "Baker's yeast", "protein_name": "Chaotic nuclear migration protein 67", "length": 581, "firstPublicDate": "1996-10-01", "FUNCTION": "Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation, Required for the proper formation of the spindle pole body (SPB) outer plaque, May connect the outer plaque to the central plaque embedded in the nuclear envelope", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTDFDLMNFPFHERLDSPVSENGEIKDGEPIPQNWLNENHVGKSILPLFVNPEDVINCNFSNARDSYEENKSPSMDQMNYARNTSYQESPGLQERPKNEKDKSPIGTDVHKKDVPNFIHSTPRENSSKHFTRANEQASAQPTDEHTSPDISIEDCNGAKIFLQNSLSKEDFRMLENVILGYQKKVIELGRDNLRQEERANSLQKELEAATKSNDKTLDNKKKIEEQTVLIENLTKDLSLNKEMLEKANDTIQTKHTALLSLTDSLRKAELFEIPIGILFFDLYDSEENSSKLDHILQEKYPNIKGFLCASQQEELSRISQRFKNAKAEAEDLRNELENKKIEIQTMREKNNTLIGTNKTLSKQNKILCDKFDKLTIDEKEILKGCNEEIKIKLERLNERLGSWEKSKEKYETSLKDKEKMLADAEKKTNTLSKELDNLRSRFGNLEGNTSERITIKNILQSRPDISAEECNFLMVEQIDSANLTTLQNTVKEIVLAVGIPYPKLRRKIPLLAIKLKYENIMLSNFAQRLHRQVYSQEMNLKKFTDQAYYDFMSTRRMDSIDHHLERCLDHLYDHILEKMVK", "length": 581, "molWeight": 67400, "crc64": "C4DE7631A70E695A", "md5": "C69370250F8D0F015876F1FE0F9EC359"}}
{"primaryAccession": "P53871", "text": "This is Probable glutamine amidotransferase DUG3 protein, from Baker's yeast, contains 357 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53871", "organism_name": "Baker's yeast", "protein_name": "Probable glutamine amidotransferase DUG3", "length": 357, "firstPublicDate": "1996-10-01", "FUNCTION": "Component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the DUG3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MCRFLIFKGKQPIRLSHLLTRPAHSIINQSFDSRLRLDRRRPMNGDGFGVAYYPLDTELSEDGPCLFKAITPAWNNQNLSTLAEKTKSDLVFAHVRASTYGVLSETNCHPFTYHSLCFMHNGGISNFKGIKRKLLNHIKDEYLNFIQGSTDSECAFALFLDTLDKLGYDPKKQDGDFGNVALRKAMLRTIDYIRDWTKEANKDEAHVEPSLLNFAVTDGSTVVVSRYITSKTDEAASLHFSCGSSFVETSPGEYRVERLDRNQDVIMVASEPLTFERGDWTAVPTNSILTIKKQTILLHPIIDEYYQEDPLYLRSSTLAESKGLMGSIPLAKAVEKNVPPLEREGRTRPPTAVAHIA", "length": 357, "molWeight": 40181, "crc64": "AFAAEFE7152CFE1A", "md5": "EE431D566A0BEC04C08A9EBF8D43788E"}}
{"primaryAccession": "P53923", "text": "This is Cytoplasmic tRNA 2-thiolation protein 2 protein, from Baker's yeast, contains 493 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53923", "organism_name": "Baker's yeast", "protein_name": "Cytoplasmic tRNA 2-thiolation protein 2", "length": 493, "firstPublicDate": "1996-10-01", "FUNCTION": "Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln), May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position, Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation, May also be involved in protein urmylation and in invasive and pseudohyphal growth, Inhibits replication of Brome mosaic virus", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CTU2/NCS2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MECQRCPASARNPATVESRKEKFCDECFIKFVSTKQRKQMMKDEYFRNLFKVIYPFEKEGSVSKILLPLSHSDSGSLVMLDIVHDLLLEQTKQHNNRTGFTVDVLTVFTEENVSVIKERMESLINEKMSQLNKISNIFNVHFIDVNEFFNNASEVSTFIIDNENFEIFSKSKSVDDSNILTLKEILGKYCLNNSSRSDLISIIKTQLIKHFAYENGYNAIMWGHSMTKLSEVIISLVVKGKGSQIATFLDSESFDTLNNKPCKYKNLYPMKDLLSVEIESFLQIRNLAQFLINVEETNVKPNCLIARKSLPSLGQQKLVKNMTINEITNKYFQDIQNDYSNIISTVLRTADKLTQPKSSMAKPSQCQICQSKIYTNPSNWLNRITVTSPYPVETTEEKYLFKQWQDSKLGQSHTHYVELLNEIKQGASNSLDVEDGDVKLCYGCLILLNTSIKDKNLVWPKVDTMDITANATNKNKELSQILDQFEINSDGEE", "length": 493, "molWeight": 56473, "crc64": "420FE465B982C43E", "md5": "D43563B39C9CD28B55AA55144165AEE4"}}
{"primaryAccession": "P53974", "text": "This is Actin-regulating kinase 1 protein, from Baker's yeast, contains 638 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53974", "organism_name": "Baker's yeast", "protein_name": "Actin-regulating kinase 1", "length": 638, "firstPublicDate": "1996-10-01", "FUNCTION": "Involved in regulation of actin cytoskeleton organization and endocytosis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNQPQIGTYNVGTQLTVGSHQVEIIKYLTSGGFAQVYSALINPPDPHSNSSVACLKRVIVPDKPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPNVYQLLKRISIMQNVPCPINDIQVVQAPSSHLNLTELHQLSATQNILSLNSPTTMENTMPNATFQISMADNTTTAQMHPNRKPSQIAYDASFSNSAKGSQPLFDKSQNMYHALDPPLVEPLASSVSNNDNELKANSATKLKQAIVSEAHTFRQNNSIDFPLQNIIPQYEDSSSSSDESYSGDVDELKKTRSLGSYSTRGNIKKNQSVKESLTSSSLPGTSFTPTSTKVNLKHENSPFKSTFVNTIDNSKDDLNKPSYEDLDVSKQNLKNSIQQRMIDKLNSSEESFNARKMSKVKLHEKGEIDKPTMLKSSGPISKDKKTKPTPPPKPSHLKPKPPPKPLLLAGRKLSLDK", "length": 638, "molWeight": 71373, "crc64": "139CA4CA1B6A181F", "md5": "0A48F3389291A16F49A21D538585046E"}}
{"primaryAccession": "P54785", "text": "This is Transcriptional activator/repressor MOT3 protein, from Baker's yeast, contains 490 amino acids, has 2 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [346, 368], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [374, 397], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "P54785", "organism_name": "Baker's yeast", "protein_name": "Transcriptional activator/repressor MOT3", "length": 490, "firstPublicDate": "1996-10-01", "FUNCTION": "Transcription factor that affects the expression of a large set of genes, Recognizes and binds to the consensus sequence 5'-[CAT]AGG[TC]A-3' in the promoter region, Plays a major role in the repression of a specific subset of hypoxic genes (e,g, ANB1, DAN1 and HEM13) under aerobic conditions, Acts synergistically with the transcription factor ROX1 to recruit the general repression complex SSN6-TUP1 to the promoter of hypoxic genes, Represses transcription of ergosterol biosynthetic genes, Negatively regulates pheromone-induced gene expression, Can act as a transcriptional activator (e,g, of genes like CYC1, SUC2 and the Ty long terminal repeat delta promoter)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNADHHLQQQQQQRQQHQQQQHQQQQHQHQHQQQQHTILQNVSNTNNIGSDSLASQPFNTTTVSSNKDDVMVNSGARELPMPLHQQQYIYPYYQYTSNNSNNNNVTAGNNMSASPIVHNNSNNSNNSNISASDYTVANNSTSNNNNNNNNNNNNNNNIHPNQFTAAANMNSNAAAAAYYSFPTANMPIPQQDQQYMFNPASYISHYYSAVNSNNNGNNAANNGSNNSSHSAPAPAPGPPHHHHHHSNTHNNLNNGGAVNTNNAPQHHPTIITDQFQFQLQQNPSPNLNLNINPAQPLHLPPGWKINTMPQPRPTTAPNHPPAPVPSSNPVASNLVPAPSSDHKYIHQCQFCEKSFKRKSWLKRHLLSHSQQRHFLCPWCLSRQKRKDNLLQHMKLKHTNYLLDELKKNNIIFNYNNSSSSNNNNDNNNNNNSNSASGSGGAGAAAAAATAPENEDGNGYDTNIKTLINDGVLNKDDVKRVLNNLIVSHNK", "length": 490, "molWeight": 54382, "crc64": "4D0DA8DE43F171ED", "md5": "32345D4E43685E204A9CEA870E5460D5"}}
{"primaryAccession": "P55830", "text": "This is Small ribosomal subunit protein eS1 protein, from Fruit fly, contains 268 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P55830", "organism_name": "Fruit fly", "protein_name": "Small ribosomal subunit protein eS1", "length": 268, "firstPublicDate": "1997-11-01", "FUNCTION": "Essential for oogenesis; required for late follicle cell development", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAVGKNKGLSKGGKKGGKKKVVDPFSRKDWYDVKAPNMFQTRQIGKTLVNRTQGQRIASDYLKGRVFEVSLADLQKDIDPERSFRKFRLIAEDVQDRNVLCNFHGMDLTTDKYRSMVKKWQTLIEAIVEAKTVDGYLLRVFCIGFTAKDQQSQRKTCYAQQSQVRKIRARMTDIITNEVSGADLKQLVNKLALDSIAKDIEKSCQRIYPLHDVYIRKVKVLKKPRFDVSKLLELHGDGGGKSVEAVVSSEGAVIDRPEGYEPPVQEAV", "length": 268, "molWeight": 30340, "crc64": "EA407157F81955C6", "md5": "01E3A94C58AD043665C9117CEE125392"}}
{"primaryAccession": "P55861", "text": "This is DNA replication licensing factor mcm2 protein, from African clawed frog, contains 886 amino acids, has 1 C4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [314, 340], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "P55861", "organism_name": "African clawed frog", "protein_name": "DNA replication licensing factor mcm2", "length": 886, "firstPublicDate": "1997-11-01", "FUNCTION": "Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells, Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built, The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit, The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity, Required for the entry in S phase and for cell division", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCM family", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MADSSESFNIATSPRAGSRRDALTSSPGRDLPPFEDESEGMFGDGVVPEEEEDGEELIGDAMERDYRPISELDRYEVEGLDDEEDVEDLTASQREAAEQSMRMRDREMGRELGRMRRGLLYDSDEEEEDRPARKRRMAERAAEGAPEEDEEMIESIENLEDMKGHTVREWVSMAATRLEIYHRFKNFLRTHVDEHGHNVFKEKISDMCKENKESLPVNYEDLAAREHVLAYFLPEAPAEMLKIFDEAAKEVVLVMYPKYDRIAREIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTCCTGVLPQLSMVKYNCNKCNFILGPFFQSQNQEVRPGSCPECQSFGPFEINMEETVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHITKKDDKVAVGELTDEDVKAIVALSKDERIGERIFASIAPSIYGHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVTKEWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAASNPIGGRYDPSLTFSENVDLTEPIVSRFDILCVVRDTVDPVQDEMLARFVVSSHIKHHPSSKDIANGDAAEFALPNTFGVEALPQEVLKKYIMYAKEKIRPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVVEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLAFRRDNNELLLFVLKQLIAEQVTYQRNRYGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSDLFKMNKFTHDVKKKLIIQQF", "length": 886, "molWeight": 100262, "crc64": "524C7B3673E2B2DD", "md5": "76DB28D746E54D19DCF9E24812B20535"}}
{"primaryAccession": "P56574", "text": "This is Isocitrate dehydrogenase [NADP], mitochondrial protein, from Rat, contains 452 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P56574", "organism_name": "Rat", "protein_name": "Isocitrate dehydrogenase [NADP], mitochondrial", "length": 452, "firstPublicDate": "1998-12-15", "FUNCTION": "Plays a role in intermediary metabolism and energy production, It may tightly associate or interact with the pyruvate dehydrogenase complex", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGYLRAVSSLCRASGSTRTWAPAALNVPSWPEQPRRHYAEKRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVVDRAGMFKLVFTPKDGSGAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTIMKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ", "length": 452, "molWeight": 50967, "crc64": "2466E1CC2C2CE9D1", "md5": "93B7781922F22FD34BB23FFFBE3203A2"}}
{"primaryAccession": "P57052", "text": "This is Splicing regulator RBM11 protein, from Human, contains 281 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P57052", "organism_name": "Human", "protein_name": "Splicing regulator RBM11", "length": 281, "firstPublicDate": "2000-12-01", "FUNCTION": "Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation, Antagonizes SRSF1-mediated BCL-X splicing, May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFPAQEEADRTVFVGNLEARVREEILYELFLQAGPLTKVTICKDREGKPKSFGFVCFKHPESVSYAIALLNGIRLYGRPINVQYRFGSSRSSEPANQSFESCVKINSHNYRNEEMLVGRSSFPMQYFPINNTSLPQEYFLFQKMQWHVYNPVLQLPYYEMTAPLPNSASVSSSLNHVPDLEAGPSSYKWTHQQPSDSDLYQMTAPLPNSASVSSSLNHVPDLEAGPSSYKWTHQQPSDSDLYQMNKRKRQKQTSDSDSSTDNNRGNECSQKFRKSKKKKRY", "length": 281, "molWeight": 32179, "crc64": "0F9478888F6F1D98", "md5": "995143C0DAA8B7A83CAEDD69443E0AE5"}}
{"primaryAccession": "P57727", "text": "This is Transmembrane protease serine 3 protein, from Human, contains 454 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P57727", "organism_name": "Human", "protein_name": "Transmembrane protease serine 3", "length": 454, "firstPublicDate": "2001-01-11", "FUNCTION": "Probable serine protease that plays a role in hearing, Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity), Activates ENaC (in vitro)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGENDPPAVEAPFSFRSLFGLDDLKISPVAPDADAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERDLKT", "length": 454, "molWeight": 49405, "crc64": "57ECC3678F7D6AFF", "md5": "473A71BE79E0F8AE01BB39AC0CC9389B"}}
{"primaryAccession": "P59055", "text": "This is Cysteine/serine-rich nuclear protein 3 protein, from Mouse, contains 597 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P59055", "organism_name": "Mouse", "protein_name": "Cysteine/serine-rich nuclear protein 3", "length": 597, "firstPublicDate": "2002-10-25", "FUNCTION": "Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity, Plays a role in apoptosis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the AXUD1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRSQGTCDNAAAMSGILKRKFEDVDASSPCSSARESDDEVSSSESADSGDSVNPSTSNHFTPSSILKREKRLRTKNVHFSCVTVYYFTRRQGFTSVPSQGGSTLGMSSRHNSVRQYTLGEFAREQERLHREMLREHLREEKLNSLKLKMTKNGTVESEEASTLTVDDISDDDIDLDNTEVDEYFFLQPLPTKKRRALLRASGVKKIDVDEKHELRAIRLSREDCGCDCRVFCDPETCTCSLAGIKCQVDRMSFPCGCTKEGCSNTAGRIEFNPIRVRTHFLHTIMKLELEKNREQQTPTLNGCHGEISAHGPSMGPVAHSVEYSIADNFEIETEPQAAVLHLQEELDCQGDEEEEEEDGSSFCSGATDSSTQSLAPSESDEEEEEEEEEEEEEEEDDDDDKGDGFVEGLGAHTEVVPLPSVLCYSDGTAVHESHTKNASFYASSSTLYYQIDSHIPGTPSQLSDNYSERDTVKNGALSLVPYAMTPERFVDYARQAEEAYGASHYPAANPSVIVCCPTSENDSGVPCNPLYPEHRSNLPQVEFHSYLKGPAQEGFVSTLNGDSHISEHPAENPLSLAEKSRLHEECIQSPVVETVPV", "length": 597, "molWeight": 66121, "crc64": "20AEA5E37793E522", "md5": "F15B02840E8A8FCD849F1A4370B13709"}}
{"primaryAccession": "P59942", "text": "This is Mitochondrial coiled-coil domain protein 1 protein, from Human, contains 119 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P59942", "organism_name": "Human", "protein_name": "Mitochondrial coiled-coil domain protein 1", "length": 119, "firstPublicDate": "2003-10-31", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVLPLPWLSRYHFLRLLLPSWSLAPQGSHGCCSQNPKASMEEQTSSRGNGKMTSPPRGPGTHRTAELARAEELLEQQLELYQALLEGQEGAWEAQALVLKIQKLKEQMRRHQESLGGGA", "length": 119, "molWeight": 13259, "crc64": "0EA678C3DFC1C5AB", "md5": "4E6749508667677F7C06356472E19B8F"}}
{"primaryAccession": "P60022", "text": "This is Beta-defensin 1 protein, from Human, contains 68 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P60022", "organism_name": "Human", "protein_name": "Beta-defensin 1", "length": 68, "firstPublicDate": "2003-11-21", "FUNCTION": "Has bactericidal activity, May act as a ligand for C-C chemokine receptor CCR6, Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner, Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the beta-defensin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK", "length": 68, "molWeight": 7420, "crc64": "B0AB76DEC3B14F94", "md5": "5A6FD20B30965ECE8D83A3A980CF0708"}}
{"primaryAccession": "P61588", "text": "This is Rho-related GTP-binding protein RhoE protein, from Mouse, contains 244 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P61588", "organism_name": "Mouse", "protein_name": "Rho-related GTP-binding protein RhoE", "length": 244, "firstPublicDate": "2004-05-24", "FUNCTION": "Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the small GTPase superfamily, Rho family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTVM", "length": 244, "molWeight": 27368, "crc64": "DD2D4021CD42BACC", "md5": "7B77DCEA7BF19679F90E80E8A5627B9F"}}
{"primaryAccession": "P61769", "text": "This is Beta-2-microglobulin protein, from Human, contains 119 amino acids, has 1 Ig-like C1-type Immunoglobulin domain, is soluble, locates in Extracellular.", "functionDomainRange": [{"location": [25, 113], "description": "Ig-like C1-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C1-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "P61769", "organism_name": "Human", "protein_name": "Beta-2-microglobulin", "length": 119, "firstPublicDate": "1986-07-21", "FUNCTION": "Component of the class I major histocompatibility complex (MHC), Involved in the presentation of peptide antigens to the immune system, Exogenously applied M,tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the beta-2-microglobulin family", "domain_description": {"Ig-like C1-type Immunoglobulin domain": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM", "length": 119, "molWeight": 13715, "crc64": "AFD2DBEF07DCEF27", "md5": "67FB16DCA90B73ADCAEFC336A6190817"}}
{"primaryAccession": "P61964", "text": "This is WD repeat-containing protein 5 protein, from Human, contains 334 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P61964", "organism_name": "Human", "protein_name": "WD repeat-containing protein 5", "length": 334, "firstPublicDate": "2004-06-07", "FUNCTION": "Contributes to histone modification (PubMed:19131338, PubMed:19556245, PubMed:19103755, PubMed:20018852, PubMed:16600877, PubMed:16829960), May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4' (PubMed:16829960), As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3 (PubMed:19556245), H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (PubMed:18840606), As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:19103755, PubMed:20018852), May regulate osteoblasts differentiation (By similarity), In association with RBBP5 and ASH2L, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (PubMed:21220120, PubMed:22266653)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WD repeat WDR5/wds family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC", "length": 334, "molWeight": 36588, "crc64": "4BF30914A2250286", "md5": "C53BEFFCED3379E8AF15BCFECD568646"}}
{"primaryAccession": "P61965", "text": "This is WD repeat-containing protein 5 protein, from Mouse, contains 334 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P61965", "organism_name": "Mouse", "protein_name": "WD repeat-containing protein 5", "length": 334, "firstPublicDate": "2004-06-07", "FUNCTION": "Contributes to histone modification (By similarity), May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4' (By similarity), As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3 (By similarity), H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (By similarity), As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (By similarity), May regulate osteoblasts differentiation (PubMed:11551928), In association with RBBP5 and ASH2L, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WD repeat WDR5/wds family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC", "length": 334, "molWeight": 36588, "crc64": "4BF30914A2250286", "md5": "C53BEFFCED3379E8AF15BCFECD568646"}}
{"primaryAccession": "P62487", "text": "This is DNA-directed RNA polymerase II subunit RPB7 protein, from Human, contains 172 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P62487", "organism_name": "Human", "protein_name": "DNA-directed RNA polymerase II subunit RPB7", "length": 172, "firstPublicDate": "2004-07-19", "FUNCTION": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs, Pol II is the central component of the basal RNA polymerase II transcription machinery, It is composed of mobile elements that move relative to each other, RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element, The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft, The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity), Binds RNA", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGAGVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS", "length": 172, "molWeight": 19294, "crc64": "AF3CE655F658CD5C", "md5": "91983F2BABC4BF7EB49EAE56EB6FA863"}}
{"primaryAccession": "P62875", "text": "This is DNA-directed RNA polymerases I, II, and III subunit RPABC5 protein, from Human, contains 67 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P62875", "organism_name": "Human", "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "length": 67, "firstPublicDate": "2004-08-16", "FUNCTION": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively, Pol II is the central component of the basal RNA polymerase II transcription machinery, Pols are composed of mobile elements that move relative to each other, In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIIPVRCFTCGKIVGNKWEAYLGLLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEK", "length": 67, "molWeight": 7645, "crc64": "9E8A72F667FE7EC5", "md5": "9684C36532449A54E52705293C7A6BF8"}}
{"primaryAccession": "P69391", "text": "This is Alpha-pompilidotoxin protein, from Solitary wasp, contains 56 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P69391", "organism_name": "Solitary wasp", "protein_name": "Alpha-pompilidotoxin", "length": 56, "firstPublicDate": "2005-03-01", "FUNCTION": "Inhibits sodium channels (Nav) inactivation, Shows two types of inhibitory activities on channels, Inhibition of hNav1,6/SCN8A shows a large increase in the steady-state current component without any increase in the slow component, whereas inhibition of hNav1,1/SCN1A, hNav1,2/SCN2A, hNav1,3/SCN3A and hNav1,7/SCN9A shows a large increase in the slow component with only a small steady-state component (PubMed:20059541), Is 5-fold less potent than beta-PMTX for inducing repetitive action potentials in lobster neuromuscular junctions", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFKQLILLALAAVFLLINISSAEPAAEPNANAEPLAEASAEPRIKIGLFDQLSKLG", "length": 56, "molWeight": 5920, "crc64": "12FEF411CBB5991F", "md5": "01948A50FA4CBE81121E428551697692"}}
{"primaryAccession": "P70041", "text": "This is Cerberus protein, from African clawed frog, contains 270 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P70041", "organism_name": "African clawed frog", "protein_name": "Cerberus", "length": 270, "firstPublicDate": "2007-01-23", "FUNCTION": "Inhibits wnt, nodal/nr-1 and bmp signaling in the embryo to promote head formation and anterior neural induction, Within the endoderm, acts as an essential mediator of nodal/nr-1-induced cardiogenesis in the overlying mesoderm", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the DAN family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLLNVLRICIIVCLVNDGAGKHSEGRERTKTYSLNSRGYFRKERGARRSKILLVNTKGLDEPHIGHGDFGLVAELFDSTRTHTNRKEPDMNKVKLFSTVAHGNKSARRKAYNGSRRNIFSRRSFDKRNTEVTEKPGAKMFWNNFLVKMNGAPQNTSHGSKAQEIMKEACKTLPFTQNIVHENCDRMVIQNNLCFGKCISLHVPNQQDRRNTCSHCLPSKFTLNHLTLNCTGSKNVVKVVMMVEECTCEAHKSNFHQTAQFNMDTSTTLHH", "length": 270, "molWeight": 30723, "crc64": "ADBB9159F500399F", "md5": "A62E1676AEC13B7F269A71483D341D4A"}}
{"primaryAccession": "P70056", "text": "This is Forkhead box protein H1 protein, from African clawed frog, contains 518 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P70056", "organism_name": "African clawed frog", "protein_name": "Forkhead box protein H1", "length": 518, "firstPublicDate": "2001-08-14", "FUNCTION": "Transcriptional activator, Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3', Upon TGF-beta induction, forms a transcriptionally active complex with smad2 and smad4 called activin-responsive factor 1 (ARF1), which binds a site on the mix-B/mix,2 promoter called the activin response element (ARE), Binds to activated smads and the ARE with much lower affinity than fast3, Necessary for the first steps in mesoderm specification, directly inducing mesodermal genes, Acts with fast3 to control the convergent extension movements of gastrulation, Binds to the proximal element (PE) of the gsc gene and cooperates with gtf2ird1/wbscr11 and SMAD proteins to regulate gsc transcription", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRDPSSLYSGFPAGSQYESVEPPSLALLSSIDQEQLPVATGQSYNHSVQHWPQPWPPLSLYREGGTWSPDRGSMYGLSPGTHEGSCTHTHEGPKDSMAGDQTRSRKSKKKNYHRYNKPPYSYLAMIALVIQNSPEKRLKLSQILKEVSTLFPFFNGDYMGWKDSIRHNLSSSDCFKKILKDPGKPQAKGNFWTVDVSRIPLDAMKLQNTALTRGGSDYFVQDLAPYILHNYKYEHNAGAYGHQMPPSHARSLSLAEDSQQTNTGGKLNTSFMIDSLLHDLQEVDLPDASRNLENQRISPAVAMNNMWSSAPLLYTHSKPTRNARSPGLSTIHSTYSSSSSSISTISPVGFQKEQEKSGRQTQRVGHPIKRSREDDDCSTTSSDPDTGNYSPIEPPKKMPLLSLDLPTSYTKSVAPNVVAPPSVLPFFHFPRFTYYNYGPSPYMTPPYWGFPHPTNSGGDSPRGPQSPLDLDNMLRAMPPNKSVFDVLTSHPGDLVHPSFLSQCLGSSGSPYPSRQGLM", "length": 518, "molWeight": 57445, "crc64": "1BEC587943F92D1F", "md5": "01C6FF4A546CF150887A8B603951E7C3"}}
{"primaryAccession": "P70158", "text": "This is Acid sphingomyelinase-like phosphodiesterase 3a protein, from Mouse, contains 445 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P70158", "organism_name": "Mouse", "protein_name": "Acid sphingomyelinase-like phosphodiesterase 3a", "length": 445, "firstPublicDate": "2001-08-29", "FUNCTION": "Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:26792860), Has in vitro activity with p-nitrophenyl-TMP, Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates, Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine, Has in vitro activity with CDP-ethanolamine, Does not have sphingomyelin phosphodiesterase activity (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the acid sphingomyelinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALLGNFLCCLLVAWLCGPGLGVPLAPADRAPAVGQFWHVTDLHLDPTYHITDDRTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTGTVIKVITNMTMTVQNLFPNLQVFPALGNHDYWPQDQLPIVTSKVYSAVADLWKPWLGEEAISTLKKGGFYSQKVASNPGLRIISLNTNLYYGPNIMTLNKTDPANQFEWLENTLNSSLWNKEKVYIIAHVPVGYLPYATDTPAIRQYYNEKLLDIFRRYSSVIAGQFYGHTHRDSLMVLSDKNGNPLNSVFVAPAVTPVKGVLQKETNNPGVRLFQYKPGDYTLLDMVQYYLNLTEANLKGESNWTLEYVLTQAYSVADLQPKSLYALVQQFATKDSKQFLKYYHYYFVSYDSSATCDQHCKTLQVCAIMNLDSMSYDDCLKQHL", "length": 445, "molWeight": 49858, "crc64": "20D986E3463CB720", "md5": "6865BD3C5740B62BBA6CEA7D15F6E1CC"}}
{"primaryAccession": "P70279", "text": "This is Surfeit locus protein 6 protein, from Mouse, contains 355 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P70279", "organism_name": "Mouse", "protein_name": "Surfeit locus protein 6", "length": 355, "firstPublicDate": "1999-07-15", "FUNCTION": "Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA, May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SURF6 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASLLAKDTYLQDLAKKICAQPGPERQRSTWGVRTKGSEAAGAPKKKRKKTQKKSPEQEQKAMDHKTKALGKKPPTSSRPKNPMVSKQEKGLSSLGSPKDSQGTARESVFALDFLRQRLHEKIQLARGQGSTKELSAATLEKRQRRKQERERKKRKRKERQAKQQVAEAEKKEEPVEVTPKMACKELQESGLIFNKVEVTEEEPASKAQRKKEKRQKVKGNLTPLTGRNYRQLLDRLQARQGRLDELRDQDAAKAQELEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRKWEKRSEHVVEKMQQRQDKRRQNLRKKKAARAERRLQKAHKKGRVLPQDLERAGLS", "length": 355, "molWeight": 41235, "crc64": "8C55841EDD8259B8", "md5": "DD14BADC3BE02C8CCBFD345E9E0E588C"}}
{"primaryAccession": "P70281", "text": "This is Synaptonemal complex protein 3 protein, from Mouse, contains 254 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P70281", "organism_name": "Mouse", "protein_name": "Synaptonemal complex protein 3", "length": 254, "firstPublicDate": "1998-07-15", "FUNCTION": "Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:11311943, PubMed:22761579), Required for centromere pairing during meiosis in male germ cells (PubMed:22761579), Required for normal meiosis during spermatogenesis and male fertility (PubMed:10678170), Plays a lesser role in female fertility (PubMed:10678170, PubMed:12004129), Required for efficient phosphorylation of HORMAD1 and HORMAD2 (PubMed:22346761)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the XLR/SYCP3 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRGCGDSDSSPEPLSKHLKMVPGGRKHSGKSGKPPLVDQPKKAFDFEKDDKDLSGSEEDVADEKAPVIDKHGKKRSAGIIEDVGGEVQNMLEKFGADINKALLAKRKRIEMYTKASFKASNQKIEQIWKTQQEEIQKLNNEYSQQFMNVLQQWELDIQKFEEQGEKLSNLFRQQQKIFQQSRIVQSQRMFAMKQIHEQFIKSLEDVEKNNDNLFTGTQSELKKEMAMLQKKVMMETQQQEMANVRKSLQSMLF", "length": 254, "molWeight": 29347, "crc64": "E0121D58A8DCD2EA", "md5": "9827860C92778FA82AB4C7E9C47688F9"}}
{"primaryAccession": "P70406", "text": "This is Dicarboxylate carrier SLC25A8 protein, from Mouse, contains 309 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P70406", "organism_name": "Mouse", "protein_name": "Dicarboxylate carrier SLC25A8", "length": 309, "firstPublicDate": "1997-11-01", "FUNCTION": "Antiporter that exports dicarboxylate intermediates of the Krebs cycle in exchange for phosphate plus a proton across the inner membrane of mitochondria, a process driven by mitochondrial motive force with an overall impact on glycolysis, glutaminolysis and glutathione-dependent redox balance, Continuous export of oxaloacetate and related four-carbon dicarboxylates from mitochondrial matrix into the cytosol negatively regulates the oxidation of acetyl-CoA substrates via the Krebs cycle lowering the ATP/ADP ratio and reactive oxygen species (ROS) production (By similarity), Proton transporter activity is debated, but if it occurs it may mediate inducible proton re-entry into the mitochondrial matrix affecting ATP turnover as a protection mechanism against oxidative stress, Proton re-entry may be coupled to metabolite transport to allow for proton flux switching and optimal ATP turnover (PubMed:12011051, PubMed:11756659) (By similarity), Regulates the use of glucose as a source of energy, Required for glucose-induced DRP1-dependent mitochondrial fission and neuron activation in the ventromedial nucleus of the hypothalamus (VMH), This mitochondrial adaptation mechanism modulates the VMH pool of glucose-excited neurons with an impact on systemic glucose homeostasis (PubMed:26919426), Regulates ROS levels and metabolic reprogramming of macrophages during the resolution phase of inflammation, Attenuates ROS production in response to IL33 to preserve the integrity of the Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages (PubMed:34644537), Can unidirectionally transport anions including L-malate, L-aspartate and phosphate (By similarity), Does not mediate adaptive thermogenesis (PubMed:11101840)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCAELVTYDLIKDTLLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYHSAGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMAAYQSREAPF", "length": 309, "molWeight": 33374, "crc64": "329794EEA99810E5", "md5": "BE88466ADD73C28902FFECDF04817CE6"}}
{"primaryAccession": "P70414", "text": "This is Sodium/calcium exchanger 1 protein, from Mouse, contains 970 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P70414", "organism_name": "Mouse", "protein_name": "Sodium/calcium exchanger 1", "length": 970, "firstPublicDate": "1997-11-01", "FUNCTION": "Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:8659820), Contributes to Ca(2+) transport during excitation-contraction coupling in muscle (PubMed:8659820), In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum (PubMed:8659820), SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline (PubMed:10967099), Required for normal embryonic heart development and the onset of heart contractions (PubMed:10967099)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2,A,19) family, SLC8 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRLSLPPNVSMGFRLVALVALLFSHVDHITADTEAETGGNETTECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPASKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNMEMAENDPVSKIFFEQGTYQCLENCGTVALTIMRRGGDLSTTVFVDFRTEDGTANAASDYEFTEGTVIFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVRVSSDVSEDGILESNHASSIACLGSPSTATITIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIIPYKTIEGTARGGGEDFEDTCGEPEFQNDEIVKTISVKVIDDEEYEKNKTFFIEIGEPRLVEMSEKKALLLNELGGFTLTGKEMYGQPIFRKVHARDHPIPSTVITISEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIQESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSSLFVLLWLLYIFFSSLEAYCHIKGF", "length": 970, "molWeight": 108035, "crc64": "F5FC0BD07F2B6602", "md5": "D575683AE9D4535518EB8B6D96888401"}}
{"primaryAccession": "P78508", "text": "This is ATP-sensitive inward rectifier potassium channel 10 protein, from Human, contains 379 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P78508", "organism_name": "Human", "protein_name": "ATP-sensitive inward rectifier potassium channel 10", "length": 379, "firstPublicDate": "1997-11-01", "FUNCTION": "May be responsible for potassium buffering action of glial cells in the brain, Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it, Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages, The inward rectification is mainly due to the blockage of outward current by internal magnesium, Can be blocked by extracellular barium and cesium (By similarity), In the kidney, together with KCNJ16, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the inward rectifier-type potassium channel (TC 1,A,2,1) family, KCNJ10 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTSVAKVYYSQTTQTESRPLMGPGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEESLREQAEKEGSALSVRISNV", "length": 379, "molWeight": 42508, "crc64": "D9DA013FF4003533", "md5": "67611AFA27E8CC1CD8EA6744B48FDE64"}}
{"primaryAccession": "P80188", "text": "This is Neutrophil gelatinase-associated lipocalin protein, from Human, contains 198 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P80188", "organism_name": "Human", "protein_name": "Neutrophil gelatinase-associated lipocalin", "length": 198, "firstPublicDate": "1993-04-01", "FUNCTION": "Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development (PubMed:12453413, PubMed:27780864, PubMed:20581821), Binds iron through association with 2,3-dihydroxybenzoic acid (2,3-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context, Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration, In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration, Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis (By similarity), Involved in innate immunity; limits bacterial proliferation by sequestering iron bound to microbial siderophores, such as enterobactin (PubMed:27780864), Can also bind siderophores from M,tuberculosis (PubMed:15642259, PubMed:21978368)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the calycin superfamily, Lipocalin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPLGLLWLGLALLGALHAQAQDSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGCQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG", "length": 198, "molWeight": 22588, "crc64": "CD761805723FEF1E", "md5": "99C396A5AC6494D13F871A4E289B6E34"}}
{"primaryAccession": "P80269", "text": "This is NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial protein, from Potato, contains 229 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P80269", "organism_name": "Potato", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "length": 229, "firstPublicDate": "1994-02-01", "FUNCTION": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis, Complex I functions in the transfer of electrons from NADH to the respiratory chain, The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity), May donate electrons to ubiquinone", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the complex I 23 kDa subunit family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAILARKSLSALRSRQLVLAGHTIEGTNGYNRTLLGTRSFATKHSFSTDKDDEEREQLAKELSKDWNSVFERSINTLFLTEMVRGLMLTLKYFFEKKVTINYPFEKGPLSPRFRGEHALRRYATGEERCIACKLCEAICPAQAITIEAEEREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETHEELLYDKEKLLENGDRWETEIAENLRSESLYR", "length": 229, "molWeight": 26378, "crc64": "D995415DBE064A93", "md5": "E2666ABB109806D789AA93D7EEF0C59A"}}
{"primaryAccession": "P82612", "text": "This is Phosphoglycerate mutase protein, from Yeast, contains 248 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P82612", "organism_name": "Yeast", "protein_name": "Phosphoglycerate mutase", "length": 248, "firstPublicDate": "2001-01-11", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the phosphoglycerate mutase family, BPG-dependent PGAM subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPKLVLVRHGQSEWNEKNLFTGWVDVRLSETGQKEAKRAGELLKEAGINVDVLHTSKLSRAIQTANIALDAADQLYVPVKRSWRLNERHYGALQGKDKAQTLEAYGQEKFQIWRRSFDVPPPKIDPKDEYSQVGDRRYADVDPAVVPLTESLALVIDRLLPYWQDEIAGDLLAGKVVLIAAHGNSLRALVKHLDNISDEDIAGLNIPTGIPLVYELDENLKPTKPSYYLDPEAAAAGAAAVAAQGQKK", "length": 248, "molWeight": 27454, "crc64": "5CC0282E8EFCC6A2", "md5": "FD99B4A0669FF099EFBFCD2D81371901"}}
{"primaryAccession": "P83673", "text": "This is Lysozyme 1 protein, from Eastern oyster, contains 184 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83673", "organism_name": "Eastern oyster", "protein_name": "Lysozyme 1", "length": 184, "firstPublicDate": "2004-04-13", "FUNCTION": "Has antibacterial activity against the Gram-positive bacteria L,garvieae, M,luteus and Enterococcus sp,, and the Gram-negative bacteria E,coli and V,vulnificus, Weak antibacterial activity against the Gram-negative bacterium A,hydrophila, No antibacterial activity detected against the Gram-positive bacterium S,iniae or against the Gram-negative bacterium E,ictaluri, Shows some chitinase activity but no isopeptidase activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 22 family, Type-I lysozyme subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNGLILFCAVVFATAVCTYGSDAPCLRAGGRCQHDSITCSGRYRTGLCSGGVRRRCCVPSSSNSGSFSTGMVSQQCLRCICNVESGCRPIGCHWDVNSDSCGYFQIKRAYWIDCGSPGGDWQTCANNLACSSRCVQAYMARYHRRSGCSNSCESFARIHNGGPRGCRNSNTEGYWRRVQAQGCN", "length": 184, "molWeight": 19986, "crc64": "239FC8C991546523", "md5": "E60C224C176E8368B5A67A448CEE73B6"}}
{"primaryAccession": "P83774", "text": "This is Small ribosomal subunit protein RACK1 protein, from Yeast, contains 317 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83774", "organism_name": "Yeast", "protein_name": "Small ribosomal subunit protein RACK1", "length": 317, "firstPublicDate": "2005-01-04", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable), Located at the head of the 40S ribosomal subunit in the vicinity of the mRNA exit channel, it serves as a scaffold protein that can recruit other proteins to the ribosome (By similarity), Involved in the negative regulation of translation of a specific subset of proteins (By similarity), Plays a role in morphogenesis and pathogenesis (PubMed:20929924)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the WD repeat G protein beta family, Ribosomal protein RACK1 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MADQEVLVLRGTLEGHNGWVTSLATTPAHPDLLLSGSRDKTLIKWKLTGGEDNQYGIPKKSFKGHSHIVQDVTISADGAYALSASWDRTLRLWDLETGETTQRFVGHKGDVLSVSIAKNLRQIVSASRDKTVKVWNTIGECMATLTGHNDWVSAVRISPSDQSSTVISASWDKTVKSWDLADYSVNADFIGHTGYISCITLSPDGSLCASAGKDGVIILWDLNKNKTLYTLEAKAEVHALAFSPNRYWLAAATTSGIKIFKLQERSLLDELKPEFAVGATAKDPEAISLAWSADGQNLFAGYTDNVIRVWQVMTPSA", "length": 317, "molWeight": 34555, "crc64": "C31FFE7FFAB153B8", "md5": "7B06F5A75EC8E3BD8C6A295A8B172010"}}
{"primaryAccession": "P84787", "text": "This is Thrombin-like enzyme elegaxobin-2 protein, from Elegant pitviper, contains 233 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P84787", "organism_name": "Elegant pitviper", "protein_name": "Thrombin-like enzyme elegaxobin-2", "length": 233, "firstPublicDate": "2006-03-07", "FUNCTION": "Thrombin-like snake venom serine protease that clots rabbit fibrinogen, Only the beta chain of fibrinogen (FGB) is cleaved, releasing fibrinopeptide B, Human and bovine fibrinogen are unaffected, Also cleaves Met-Lys and Arg-Ser bonds in heat-denatured bovine plasma kininogen to release Lys-bradykinin", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Snake venom subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "VIGGDECNINEHPFLVLVYYDEYQCGGTLINEEWVLTAAHCDGENMEIHLGMHSKKVPNKDRRRRVPKEKFFCDSSKNYTKWNKDIMLIRLNRPVRKSAHIAPLSLPSSPPSVGSVCRIMGWGTISPTEETYPDVPHCANINLLDYEVCRAAYPELPATSRTLCAGILEGGKDSCGGDSGGPLICNGQFQGIVSWGGDPCAQPHEPGSYTNVFDHLDWIKGIIAGNTDATCPL", "length": 233, "molWeight": 25591, "crc64": "33C60B6914DF2134", "md5": "86633E029A28C657A284E6B0197E1A52"}}
{"primaryAccession": "P84809", "text": "This is Lipolysis-activating peptide 1-beta chain protein, from Common European scorpion, contains 95 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P84809", "organism_name": "Common European scorpion", "protein_name": "Lipolysis-activating peptide 1-beta chain", "length": 95, "firstPublicDate": "2006-04-18", "FUNCTION": "The monomer edited version, similar to alpha-toxins, may modulate voltage-gated sodium channels (Nav) and may block voltage-gated potassium channels (Kv)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the long (3 C-C) scorpion toxin superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MISVQVIFIAFISIIAFSMVCGGNVFPNRELGILYGCKGYGNAFCDKVCKMHLARGGGRCGEPNPVMWACECIDIDEDNGYFLNALEKQCPLLKG", "length": 95, "molWeight": 10386, "crc64": "EA0121562139A0B6", "md5": "4AD6B759E6B7512E0E5B4CE5A43AB4C7"}}
{"primaryAccession": "P85109", "text": "This is Thrombin-like enzyme kangshuanmei protein, from Korean slamosa snake, contains 236 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P85109", "organism_name": "Korean slamosa snake", "protein_name": "Thrombin-like enzyme kangshuanmei", "length": 236, "firstPublicDate": "2007-04-03", "FUNCTION": "Thrombin-like snake venom serine protease, Cleaves bonds after Arg and Lys, converts fibrinogen (FGA and FGB) to fibrin and releases both fibrinopeptides A and B, and fibrinogen peptide Bbeta1-42, Has a blood clotting activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Snake venom subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "VIGGDECNINEHRFLVALYHSRSRTFLCGGTLINQEWVLTAAHCDRFFMYIRLGMHNKNVNFDDEQRRSPKEKYFFRCSNNFTKWDKDIMLIRLDSPVNNSAHIAPLSLPSNPPSVGSVCRVMGWGQTTSPQEDLSDVPRCANINLFNFTVCRAAYPWLPATSRVLCAGDMEGGIDTCNRDSGGPLICNGQFQGIVSKGQNLCAQPRKPALYTKVFDHLDWIQSIIAGNKTVTCPP", "length": 236, "molWeight": 26432, "crc64": "B1579E328A6522E5", "md5": "FBB722845E09ADE3038A7EC701444CDA"}}
{"primaryAccession": "P85886", "text": "This is Alpha-conotoxin SrIA/SrIB protein, from Alphabet cone, contains 69 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P85886", "organism_name": "Alphabet cone", "protein_name": "Alpha-conotoxin SrIA/SrIB", "length": 69, "firstPublicDate": "2009-05-05", "FUNCTION": "Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them, Has weak blocking effects on muscle nAChR composed of alpha-1/beta-1/gamma/delta subunits and the central nervous system nAChR composed of alpha-4/beta-2 subunits, Does not detectably affect the peripheral nervous system nAChR composed of alpha-3/beta-4 subunits, Low toxin concentrations potentiate currents in muscle nAChR composed of alpha-1/beta-1/gamma/delta subunits and central nervous system nAChR composed of alpha-4/beta-2 subunits, but not the peripheral nervous system nAChR composed of alpha-3/beta-4 subunits", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the conotoxin A superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGMRMMFTVFLLVVLATTVVSFTSDSAFDSRNVAANDKVSDMIALTARRTCCSRPTCRMEYPELCGGRR", "length": 69, "molWeight": 7689, "crc64": "5124A4B09A970576", "md5": "A4170DC5DDD3FF35DDEB69B77F9C3CAB"}}
{"primaryAccession": "P86716", "text": "This is Spiderine-1a protein, from Lynx spider, contains 166 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86716", "organism_name": "Lynx spider", "protein_name": "Spiderine-1a", "length": 166, "firstPublicDate": "2014-03-19", "FUNCTION": "Has antimicrobial, insecticidal, cytolytic and cytotoxic activity, Active against E,coli DH5alpha, E,faecalis VKM B 871, B,subtilis VKM B 501, A,globiformis VKM Ac 1112, P,aeruginosa PAO1 and S,aureus 209P in submicromolar or low micromolar ranges, Lyses human erythrocytes, Kills HeLA and A549 cells", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the spiderine family, Cationic/spiderine subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFALVLLGVCAFYLVNATGDLETELEASELQELQEALDLIGETPLESLEAEELEEARKFKWGKLFSTAKKLYKKGKKLSKNKNFKKALKFGKQLAKNLQAGEEHEPGTPVGNNKCWAIGTTCSDDCDCCPEHHCHCPAGKWLPGLFRCTCQVTESDKVNKCPPAE", "length": 166, "molWeight": 18421, "crc64": "E5605259C728CEBA", "md5": "34990974F5B9C7AB419133275F664C48"}}
{"primaryAccession": "P86899", "text": "This is Cyclotide cter-M protein, from Butterfly pea, contains 127 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86899", "organism_name": "Butterfly pea", "protein_name": "Cyclotide cter-M", "length": 127, "firstPublicDate": "2011-09-21", "FUNCTION": "Probably participates in a plant defense mechanism, Displays insecticidal activity against H,armigera, Has weak hemolytic activity, Binds to phospholipid membranes", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the cyclotide family, Moebius subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAYVRLTSLAVLFFLAASVMKTEGGLPTCGETCTLGTCYVPDCSCSWPICMKNHIIAANAKTVNEHRLLCTSHEDCFKKGTGNYCASFPDSNIHFGWCFHAESEGYLLKDFMNMSKDDLKMPLESTN", "length": 127, "molWeight": 14078, "crc64": "F8A4C74D2270F02C", "md5": "66E3FD117249EF3DCED3D2240D1A4AD2"}}
{"primaryAccession": "P86938", "text": "This is Thymine dioxygenase JBP1 protein, from Trypanosoma brucei brucei (strain 927/4 GUTat10.1), contains 839 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86938", "organism_name": "Trypanosoma brucei brucei (strain 927/4 GUTat10.1)", "protein_name": "Thymine dioxygenase JBP1", "length": 839, "firstPublicDate": "2011-07-27", "FUNCTION": "Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU), DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation, Also specifically binds to base J-containing DNA (J-DNA), Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized DNA base J and propagating J synthesis, Thymine dioxygenase activity and J-DNA-binding are independent functions", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TET family, JBP1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRRQVKKVLREKADDSMKPGWDVYQPSNDVVYAFNHYMQGSQIDAEAREKAEKAFQEAVKKHPFHNNADHTVDFHGTTVFRNAKGKVCGVLIPKALPSFATSMAADVLECAVARTSLRSALFGGVSPNSGIAGYFDYRGTPVELKCRKTSFTYEHTKEWRSVFPMIDYTSAIYKAALPDHWKAQDAAVPDVVRIHGSPFSTLTVNERFRTASHTDNGDFDNGYGVLAVLKGEYSGLSLALDDYGVCFNMQPTDVLLFDTHLFHSNTELEAKEANATWNRLSCVFYYRAALGEQPCVEEYRRRLKKAKEEKSTSLSFNHIEQKDNGENTNKPAPVYPVSLTPFSCAASAWALRGCAAAMLTRLHGLVRENASLMTELFGEPVEVADGLPRRAPEEIIPVHKHTNVQMHYLGGFSEKGDILNEAMNKRHYLDKENLQKMFGEEFVNIWTQSRTHWLQLVKKEWEHQKETNPTRTRFSWNNTSAMNFAFFDLCDVAKQLMCGAFGDREVNKKEEQSFWGMFAAHLDNACINEIGMLQGSMGMHKLNVKLKDYNFGGTRYLKDMPPEEQERRRRRRLEIEQARRRAPICDSESGDWLRNEAFDYQTEDVAVNYEREQWITPENNAKRFGFPERGVYGAEGAATGTISVLIVLPKPTNHRQKTCELPTSREADRIMKNPAAQRLLCAKPCNIGLSTSSNKSRTVLCGNIRIDKVFDGGSVGGKMYDFVIMRHLLAATTGEREPLECLVRWTSLARYCTFVVEVDLLDRHHYILKSEIGEEYSAVSEICFSALYSATYARDKVNLRTTPCLLSFIDKSGNMLESRFKFNGSPLNTVAFVVRRREK", "length": 839, "molWeight": 95251, "crc64": "B3BEECD851CC0FE7", "md5": "29065ED51E6147C3C42A83CAFACE19A6"}}
{"primaryAccession": "P87074", "text": "This is DNA repair protein crb2 protein, from Fission yeast, contains 778 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P87074", "organism_name": "Fission yeast", "protein_name": "DNA repair protein crb2", "length": 778, "firstPublicDate": "2002-06-20", "FUNCTION": "Essential for cell cycle arrest at the G1 and G2 stages following DNA damage by X-, and UV-irradiation, or inactivation of DNA ligase, Plays a role in the response to DNA damage (PubMed:9153313, PubMed:9407031), Interaction with rad4 via its phosphorylation sites in the N-terminus couples the DNA checkpoint apparatus to chromatin via interaction of its C-terminal BRCT domains with epigenetic modifications on histones H4 and H2A, respectively, in the G1/S phase of the cell cycle, and facilitates recruitment of the checkpoint kinase chk1 (PubMed:15550243, PubMed:16778077, PubMed:18826944, PubMed:20679485, PubMed:22792081)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEVNDTSLHKGFGLDINSQRVFGAQAAISRNNYSKVNASINPSPPRSNDNSNKEFSYSKDVNNNGAVEELSLTQLFEVPSQAAFAKQSSQDISDDELIQHDSRKVISSPYSPKQTHTVLKRLYDRQSVISDHEKLLTPQNVSNSSQILSPFTSLLPSTLSTLKDTPLSVSQNEKNLETVGEVLVPETVAQHRTKFYDYTLDEMENETESGQVETTPTRLATSLGSPVLYGRVESTPPAFLPETSEKQYKRKFSFTEPSSEKVDNTETKFSKKTKNINDENFPNPFNVISSYETSASPSTVIDQSSQVSSIFVNKRLRKSVNNQAISRSDSLSLDTPKIDSLFTRASIKPLKPSQSPNSRRSFKNRVLAFFKGYPSFYYPATLVAPVHSAVTSSIMYKVQFDDATMSTVNSNQIKRFFLKKGDVVQSTRLGKIKHTVVKTFRSTNEQLSLIAVDALNNDMVILAHGEIEVTVPISTIYVAPVNIRRFQGRDLSFSTLKDMKFEETSFLPSHDSQRNRSSLKERDSSFVKKNLDSESNQLIFDDCVFAFSGPVHEDAYDRSALETVVQDHGGLVLDTGLRPLFNDPFKSKQKKLRHLKPQKRSKSWNQAFVVSDTFSRKVKYLEALAFNIPCVHPQFIKQCLKMNRVVDFSPYLLASGYSHRLDCTLSQRIEPFDTTDSLYDRLLARKGPLFGKKILFIIPEAKSWQKKIENTEQGQKALAHVYHALALGADVEIRPNVAHLECDLILTMDGNIVDETNCPVVDPEWIVECLISQSDIST", "length": 778, "molWeight": 87462, "crc64": "5E35178828E6E42A", "md5": "F2A877914EF907D3EFE9032DBB15542D"}}
{"primaryAccession": "P91685", "text": "This is Metabotropic glutamate receptor protein, from Fruit fly, contains 976 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P91685", "organism_name": "Fruit fly", "protein_name": "Metabotropic glutamate receptor", "length": 976, "firstPublicDate": "1998-07-15", "FUNCTION": "G-protein coupled receptor for glutamate, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKQKNNNGTILVVVMVLSWSRVVDLKSPSNTHTQDSVSVSLPGDIILGGLFPVHEKGEGAPCGPKVYNRGVQRLEAMLYAIDRVNNDPNILPGITIGVHILDTCSRDTYALNQSLQFVRASLNNLDTSGYECADGSSPQLRKNASSGPVFGVIGGSYSSVSLQVANLLRLFHIPQVSPASTAKTLSDKTRFDLFARTVPPDTFQSVALVDILKNFNWSYVSTIHSEGSYGEYGIEALHKEATERNVCIAVAEKVPSAADDKVFDSIISKLQKKPNARGVVLFTRAEDARRILQAAKRANLSQPFHWIASDGWGKQQKLLEGLEDIAEGAITVELQSEIIADFDRYMMQLTPETNQRNPWFAEYWEDTFNCVLTSLSVKPDTSNSANSTDNKIGVKAKTECDDSYRLSEKVGYEQESKTQFVVDAVYAFAYALHNLHNDRCNTQSDQTTETRKHLQSESVWYRKISTDTKSQACPDMANYDGKEFYNNYLLNVSFIDLAGSEVKFDRQGDGLARYDILNYQRQENSSGYQYKVIGKWFNGLQLNSETVVWNKETEQPTSACSLPCEVGMIKKQQGDTCCWICDSCESFEYVYDEFTCKDCGPGLWPYADKLSCYALDIQYMKWNSLFALIPMAIAIFGIALTSIVIVLFAKNHDTPLVRASGRELSYTLLFGILVCYCNTFALIAKPTIGSCVLQRFGIGVGFSIIYSALLTKTNRISRIFHSASKSAQRLKYISPQSQVVITTSLIAIQVLITMIWMVVEPPGTRFYYPDRREVILKCKIQDMSFLFSQLYNMILITICTIYAIKTRKIPENFNESKFIGFTMYTTCIIWLAFVPIYFGTGNSYEVQTTTLCISISLSASVALVCLYSPKVYILVFHPDKNVRKLTMNSTVYRRSAAAVAQGAPTSSGYSRTHAPGTSALTGGAVGTNASSSTLPTQNSPHLDEASAQTNVAHKTNGEFLPEVGERVEPICHIVNK", "length": 976, "molWeight": 108486, "crc64": "43A0E1F918EDACC4", "md5": "3022F039C15B4E0A46EDF5CB1019962C"}}
{"primaryAccession": "P91870", "text": "This is Spindle-defective protein 2 protein, from Caenorhabditis elegans, contains 824 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P91870", "organism_name": "Caenorhabditis elegans", "protein_name": "Spindle-defective protein 2", "length": 824, "firstPublicDate": "2005-04-12", "FUNCTION": "Required both for centrosome duplication and maturation (PubMed:15068791, PubMed:15186742, PubMed:19081077), Required for pericentriolar material (PCM) recruitment (PubMed:15068791, PubMed:15186742)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEDDAPMNLCNEQFEEIEDSPIDDNDNESFYNADGDVELEEEEVHETPKNFKNGGRFKTNMTNPKVNDLTTIEEKNEDLRSAASSRSASRPASVMSDKSFSSQFEFQSGGENAIEEYTNQVFADENKADLLFPETSKFMNGASPPKDKHHSWEPSIHHYDKQPPPDIQTNSPVFGNLNHRKNKLIPQARAKPGANDNEIVERDNDENVPTTSDKSAFITSPMNSTNHDEKTSTPKRPTNRKIGQYQGPNFDLSSIYVGSPQHQNTSISTGQQMPTSSYSHAHSETMMTNQTINESMVRRVLNGNNKNQDLFAALEEARKRRAAQPSKPDFRINTTRTRVPIKPTSARHSGNVVSSTSNDNTTAASSKDLTTSRKAMETFRQNASMADATNSNTASMTSILSTISTARTDISRSSRNHGGGFSNTSVSTVIPANNGNVSLSHGRDGRDSVSSVRTMSRASSTSTVYAGSTFSGVSKPLRIHAKRVAFGCVAVGETLRVEVEVENISDRQCLVRASTDSTTPVYQILDNKLTMVDPKKSIKFQVSFSPSSVGRYQVIMSIEVPAQNFIHKIPMWGNGGIAKFVPTSPDLQQTINQSEYAMCTSCAKRISFKISNSAGTRDGFAMIKVFDSAMRQLPDGCVAFFPAPGFIVKKKSDKRVDIRIDSSYIDLHDENNFRTSSSLSTASTTSSFQRRILPGAKFFVHVVWGEETMRTRLRLLEVRTGQHQLIDGHDFTSFQFSDEEVLRAVPVGFPAIKPEDRDLFAASYRSFFINFFTSTTEFRAATSRKKKEICSNDDSTLLETTAFRNQTFVNDVTIVPNTRFSNRK", "length": 824, "molWeight": 91531, "crc64": "6D8AA983F162A1E5", "md5": "B3AC16C0160151CFD072B6B9BA645E2A"}}
{"primaryAccession": "P91889", "text": "This is FMRFamide-related neuropeptides protein, from Common cuttlefish, contains 331 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P91889", "organism_name": "Common cuttlefish", "protein_name": "FMRFamide-related neuropeptides", "length": 331, "firstPublicDate": "2011-02-08", "FUNCTION": "Excitatory neurotransmitters that directly modulate chromatophore function by activating chromatophore expansion at the chromatophore neuromuscular junction", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the FARP (FMRFamide related peptide) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRCWSPCSLLVVIAIYCLSSHTSEAFDLAQACVESQRLSLLPICDTIFAVQQEGAQQSADDGLRSKRFIRFGRALSGDAFLRFGKNVPDLPFEDKRFLRFGRAAPQLDDLLKQALQRVESLQKSDDTSVRRKRSTDAAPQSNTDSAEQKNDSAKITKRYVDDVEDSDVKRFMRFGKRFMRFGRNPSDVGSKLTEKRFMRFGRDPEKRFMRFGKSDDKKFMRFGRNPGDAEDELEEDKRFMRFGRGDEEDEEEAEKRFMRFGRDPEKKFMRFGKNGEEKRFMRFGRNPEEPEADKRFMRFGRGGEEDDVNTEEKRFMRFGRSAEKCKGCLEG", "length": 331, "molWeight": 38594, "crc64": "157A15EAD2DBD86B", "md5": "F515C2838A7985C563E5FE256B573A3E"}}
{"primaryAccession": "P91926", "text": "This is AP-2 complex subunit alpha protein, from Fruit fly, contains 940 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P91926", "organism_name": "Fruit fly", "protein_name": "AP-2 complex subunit alpha", "length": 940, "firstPublicDate": "1998-12-15", "FUNCTION": "Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles, Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration, AP-2alpha is a subunit of the plasma membrane adapter", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the adaptor complexes large subunit family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPVRGDGMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDLQSRNPVHVNLALQCIANIGSRDMAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEWTSRIIHLLNDQHMGVVTAATSLIDALVKRNPDEYKGCVNLAVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARLNETLETILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHSDSEPNLLVRACNQLGQFLSNRETNLRYLALESMCHLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILNLIRIAGDYVSEEVWYRVIQIVINREEVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDSRSAPLVQFKLLHSKYHLCSPMTRALLLSTYIKFINLFPEIRTNIQDVFRQHSNLRSADAELQQRASEYLQLSIVASTDVLATVLEEMPSFPERESSILAVLKKKKPGRVPENEIRESKSPAPLTSAAQNNALVNNSHSKLNNSNANTDLLGLSTPPSNNIGSGSNSNSTLIDVLGDMYGSNSNNNSSAVYNTKKFLFKNNGVLFENEMLQIGVKSEFRQNLGRLGLFYGNKTQVPLTNFNPVLQWSAEDALKLNVQMKVVEPTLEAGAQIQQLLTAECIEDYADAPTIEISFRYNGTQQKFSIKLPLSVNKFFEPTEMNAESFFARWKNLSGEQQRSQKVFKAAQPLDLPGARNKLMGFGMQLLDQVDPNPDNMVCAGIIHTQSQQVGCLMRLEPNKQAQMFRLTVRASKETVTREICDLLTDQF", "length": 940, "molWeight": 105620, "crc64": "F745045CD2C1D9C5", "md5": "125C384AA6F3608D9388952F28BF99C3"}}
{"primaryAccession": "P91943", "text": "This is Protein pangolin, isoforms A/H/I/S protein, from Fruit fly, contains 751 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P91943", "organism_name": "Fruit fly", "protein_name": "Protein pangolin, isoforms A/H/I/S", "length": 751, "firstPublicDate": "1998-12-15", "FUNCTION": "Segment polarity protein, Functions together with arm to transduce the Wingless (Wg) signal in embryos and in developing adult tissues, Acts as a transcriptional activator, but in the absence of arm, it binds to gro and acts as a transcriptional repressor of wg-responsive genes", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TCF/LEF family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPHTHSRHGSSGDDLCSTDEVKIFKDEGDREDEKISSENLLVEEKSSLIDLTESEEKGHKISRPDHSPVFNKLDTHAPSFNMGYLVSPYSYANGSPSGLPVTMANKIGLPPFFCHNADPLSTPPPAHCGIPPYQLDPKMGLTRPALYPFAGGQYPYPMLSSDMSQVASWHTPSVYSASSFRTPYPSSLPINTTLASDFPFRFSPSLLPSVHATSHHVINAHSAIVGVSSKQECGVQDPTTNNRYPRNLEAKHTSNAQSNESKETTNDKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHELSREEQSKYYEKARQERQLHMELYPGWSARDNYGYVSKKKKRKKDRSTTDSGGNNMKKCRARFGLDQQSQWCKPCRRKKKCIRYMEALNGNGPAEDGSCFDEHGSQLSDDDEDDYDDDKLGGSCGSADETNKIEDEDSESLNQSMPSPGCLSGLSSLQSPSTTMSLASPLNMNANSATNVIFPASSNALLIVGADQPTAQQRPTLVSTSGSSSGSTSSISTTPNTSSTVSPVTCMTGPCLGSSQERAMMLGNRFSHLGMGLSPPVVSTSTSKSEPFFKPHPTVCNNPIFALPSIGNCSLNISSMPNTSRNPIGANPRDINNPLSINQLTKRREYKNVELIEASESKTIVAHAATSIIQHVAVNGYHANHSLLNSNLGHLHHQLNNRTENPNRSEQTMLSVSNHSVNSSECHKESDSQAIVSSNPPNAGSSDNGVISVS", "length": 751, "molWeight": 81892, "crc64": "1C6E5A0B36017143", "md5": "584B60E8E1F1FF0EEB9496EACBE1AC32"}}
{"primaryAccession": "P92990", "text": "This is Polygalacturonase 1 beta-like protein 3 protein, from Mouse-ear cress, contains 626 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P92990", "organism_name": "Mouse-ear cress", "protein_name": "Polygalacturonase 1 beta-like protein 3", "length": 626, "firstPublicDate": "2005-11-22", "FUNCTION": "Involved in cell size determination, May serve as a chaperone for expansins through the secretory pathway", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLKQFLLLQSFSFFLFNVVIVGGRTFGGGFSAEENPFTPKASLVRYWNKEIRGQSPRSEFLISKASPLNAVDSATFSKLAAANSLPTRFPDFCSAANLFCFPDLGASLEKHDDDVKFSVYDQKNFTNYGNARAGGADSFKNYSKDGNVVTDSFRRYSRNAAGHDDKFTVYGENSNVVEEGFNSYGTFGTGGAGDFTNYQNNVNNPTSRFTAYSDGGNGRSQTFKTYTHEANAGNGQSFTSYGKNGNGVPNEFTSYGVSSNVIGSGFSNYGESGNAANDTFTSYGSDGNVPQNNFNNYGASGNAAVDTFANYRDKANVGDDSFSSYAKDSNSEKVNFVNYGQSFNPGSETFTGYGKGAEGSKLSFKTYTPNSTFKDYAKKGVAFAKYNVSTTTANTVGDGKTVNKWIEPGKFFRESSLKEGTVIPMPDIKDKMPKRSFLPRSIITKLPFSTSKLGEIKRIFHAVENSTMGGIITDAVTECERPPSVGETKRCVGSAEDMIDFATSVLGRSVVLRTTENVAGSKEKVVIGKVNGINGGKLTKAVSCHQSLYPYLLYYCHSVPKVRVYEADLLELNSKKKINHGIAICHMDTSSWGPSHGAFLALGSKPGRIEVCHWIFENDMNWAIAD", "length": 626, "molWeight": 68060, "crc64": "F324231B27D4B710", "md5": "B3824B23BFD953CCCD6B3AC8516D5249"}}
{"primaryAccession": "P93025", "text": "This is Phototropin-2 protein, from Mouse-ear cress, contains 915 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P93025", "organism_name": "Mouse-ear cress", "protein_name": "Phototropin-2", "length": 915, "firstPublicDate": "2005-11-22", "FUNCTION": "Protein kinase that acts as a blue light photoreceptor in a signal-transduction pathway for photo-induced movements, Phosphorylates BLUS1, a kinase involved in stomatal opening, Mediates calcium spiking of extra- and intracellular origins in response to blue light, Involved in hypocotyl phototropism, Contributes to the chloroplast accumulation in low blue light and mediates their translocation (avoidance response) at high fluence, Regulates stomata opening and photomorphogenesis response of leaf tissue, Not involved in hypocotyl elongation inhibition, anthocyanin accumulation or cotyledon opening", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MERPRAPPSPLNDAESLSERRSLEIFNPSSGKETHGSTSSSSKPPLDGNNKGSSSKWMEFQDSAKITERTAEWGLSAVKPDSGDDGISFKLSSEVERSKNMSRRSSEESTSSESGAFPRVSQELKTALSTLQQTFVVSDATQPHCPIVYASSGFFTMTGYSSKEIVGRNCRFLQGPDTDKNEVAKIRDCVKNGKSYCGRLLNYKKDGTPFWNLLTVTPIKDDQGNTIKFIGMQVEVSKYTEGVNDKALRPNGLSKSLIRYDARQKEKALDSITEVVQTIRHRKSQVQESVSNDTMVKPDSSTTPTPGRQTRQSDEASKSFRTPGRVSTPTGSKLKSSNNRHEDLLRMEPEELMLSTEVIGQRDSWDLSDRERDIRQGIDLATTLERIEKNFVISDPRLPDNPIIFASDSFLELTEYSREEILGRNCRFLQGPETDQATVQKIRDAIRDQREITVQLINYTKSGKKFWNLFHLQPMRDQKGELQYFIGVQLDGSDHVEPLQNRLSERTEMQSSKLVKATATNVDEAVRELPDANTRPEDLWAAHSKPVYPLPHNKESTSWKAIKKIQASGETVGLHHFKPIKPLGSGDTGSVHLVELKGTGELYAMKAMEKTMMLNRNKAHRACIEREIISLLDHPFLPTLYASFQTSTHVCLITDFCPGGELFALLDRQPMKILTEDSARFYAAEVVIGLEYLHCLGIVYRDLKPENILLKKDGHIVLADFDLSFMTTCTPQLIIPAAPSKRRRSKSQPLPTFVAEPSTQSNSFVGTEEYIAPEIITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRQKTFANILHKDLTFPSSIPVSLVGRQLINTLLNRDPSSRLGSKGGANEIKQHAFFRGINWPLIRGMSPPPLDAPLSIIEKDPNAKDIKWEDDGVLVNSTDLDIDLF", "length": 915, "molWeight": 102472, "crc64": "CA163E2596289737", "md5": "C7276A7C9B01B9016761ED7E28C13022"}}
{"primaryAccession": "P93030", "text": "This is E3 ubiquitin-protein ligase RMA2 protein, from Mouse-ear cress, contains 193 amino acids, has 1 RING-type Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [21, 75], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "P93030", "organism_name": "Mouse-ear cress", "protein_name": "E3 ubiquitin-protein ligase RMA2", "length": 193, "firstPublicDate": "2010-07-13", "FUNCTION": "E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of the auxin-binding protein ERABP1", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEIEKDEDDTTLVDSGGDFDCNICLDQVRDPVVTLCGHLFCWPCIHKWTYASNNSRQRVDQYDHKREPPKCPVCKSDVSEATLVPIYGRGQKAPQSGSNVPSRPTGPVYDLRGVGQRLGEGESQRYMYRMPDPVMGVVCEMVYRRLFGESSSNMAPYRDMNVRSRRRAMQAEESLSRVYLFLLCFMFMCLFLF", "length": 193, "molWeight": 22178, "crc64": "8D2AE01F6984CD88", "md5": "3EB74595A0D22F1EBB092517A994187F"}}
{"primaryAccession": "P97361", "text": "This is BPI fold-containing family A member 1 protein, from Mouse, contains 278 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P97361", "organism_name": "Mouse", "protein_name": "BPI fold-containing family A member 1", "length": 278, "firstPublicDate": "2001-10-18", "FUNCTION": "Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC) (By similarity), Plays a role in the innate immune responses of the upper airways (PubMed:23499554), Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P,aeruginosa and K,pneumoniae (PubMed:23499554), Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus (By similarity), Plays a role in the airway inflammatory response after exposure to irritants (By similarity), May attract macrophages and neutrophils (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the BPI/LBP/Plunc superfamily, Plunc family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFLVGSLVVLCGLLAHSTAQLAGLPLPLGQGPPLPLNQGPPLPLNQGQLLPLAQGLPLAVSPALPSNPTDLLAGKFTDALSGGLLSGGLLGILENIPLLDVIKSGGGNSNGLVGGLLGKLTSSVPLLNNILDIKITDPQLLELGLVQSPDGHRLYVTIPLGLTLNVNMPVVGSLLQLAVKLNITAEVLAVKDNQGRIHLVLGDCTHSPGSLKISLLNGVTPVQSFLDNLTGILTKVLPELIQGKVCPLVNGILSGLDVTLVHNIAELLIHGLQFVIKV", "length": 278, "molWeight": 28625, "crc64": "2540BED994475387", "md5": "65F1894B9C83475BCCA14256839FAEE4"}}
{"primaryAccession": "P97363", "text": "This is Serine palmitoyltransferase 2 protein, from Mouse, contains 560 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P97363", "organism_name": "Mouse", "protein_name": "Serine palmitoyltransferase 2", "length": 560, "firstPublicDate": "2000-05-30", "FUNCTION": "Serine palmitoyltransferase (SPT), The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core, The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate (By similarity), Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis (PubMed:28698261)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRPEPGGCCCRRPMRANGCVKNGEVRNGYLRSSTATVAAAGQIHHVTENGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERKSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRLVPLLDRPFDETTYEETED", "length": 560, "molWeight": 62982, "crc64": "6429566979B18D1C", "md5": "294146B5250D49D0F0F3917091C4082F"}}
{"primaryAccession": "P97368", "text": "This is Homeobox protein Meis3 protein, from Mouse, contains 378 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P97368", "organism_name": "Mouse", "protein_name": "Homeobox protein Meis3", "length": 378, "firstPublicDate": "1998-07-15", "FUNCTION": "Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells, Also regulates expression of NDFIP1, BNIP3, and CCNG1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TALE/MEIS homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MARRYDELRHYPGITEHTTALASFSEAAPSVPRAPGPYTPHRPPQLQAPGLDSDSLKREKDDIYGHPLFPLLALVFEKCELATCSPRDGASAGLGSPPGGDVCSSDSFNEDIAAFAKQIRSERPLFSSNPELDNLMVQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIEDRDGSCREDLEDYAASCPSLPDQNTTWIRDHEDSGSVHLGTPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSAGEDEDLDLERRRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTGQGASFNPEGQPMAGFTETQPQVTVRTPGSMGMNLNLEGEWHYL", "length": 378, "molWeight": 41726, "crc64": "3D0CB5FD586741B4", "md5": "548AF7A9842781E9DAAC99F75A6BEDC6"}}
{"primaryAccession": "P97430", "text": "This is Antileukoproteinase protein, from Mouse, contains 131 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P97430", "organism_name": "Mouse", "protein_name": "Antileukoproteinase", "length": 131, "firstPublicDate": "1997-11-01", "FUNCTION": "Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G (PubMed:9126337), Modulates the innate immune response after bacterial infection (PubMed:12615907), Contributes to regulate the inflammatory and immune responses to the intracellular parasite L,major (PubMed:25030421), Down-regulates responses to bacterial lipopolysaccharide (LPS) (PubMed:9039268, PubMed:12615907, PubMed:25030421), Plays a role in regulating the activation of NF-kappa-B and inflammatory responses (PubMed:11017147, PubMed:12615907), Has antimicrobial activity against mycobacteria, but not against salmonella (PubMed:18322212), Contributes to normal resistance against infection by M,tuberculosis (PubMed:18322212), Required for normal resistance to L,major (PubMed:25030421), Required for normal wound healing, probably by preventing tissue damage by limiting protease activity (PubMed:11017147, PubMed:25030421), Together with ELANE, required for normal differentiation and proliferation of bone marrow myeloid cells (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKSCGLLPFTVLLALGILAPWTVEGGKNDAIKIGACPAKKPAQCLKLEKPQCRTDWECPGKQRCCQDACGSKCVNPVPIRKPVWRKPGRCVKTQARCMMLNPPNVCQRDGQCDGKYKCCEGICGKVCLPPM", "length": 131, "molWeight": 14308, "crc64": "A57C9E30FE711B8F", "md5": "BC27E4B51B2F1C558319183CBE7E50C5"}}
{"primaryAccession": "P97468", "text": "This is Chemerin-like receptor 1 protein, from Mouse, contains 371 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P97468", "organism_name": "Mouse", "protein_name": "Chemerin-like receptor 1", "length": 371, "firstPublicDate": "1998-07-15", "FUNCTION": "Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1, Interaction with RARRES2 initiates activation of G proteins G(i)/G(o) and beta-arrestin pathways inducing cellular responses via second messenger pathways such as intracellular calcium mobilization, phosphorylation of MAP kinases MAPK1/MAPK3 (ERK1/2), TYRO3, MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis, Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B (By similarity), Positively regulates adipogenesis and adipocyte metabolism", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the chemokine-like receptor (CMKLR) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEYDAYNDSGIYDDEYSDGFGYFVDLEEASPWEAKVAPVFLVVIYSLVCFLGLLGNGLVIVIATFKMKKTVNTVWFVNLAVADFLFNIFLPMHITYAAMDYHWVFGKAMCKISNFLLSHNMYTSVFLLTVISFDRCISVLLPVWSQNHRSIRLAYMTCSAVWVLAFFLSSPSLVFRDTANIHGKITCFNNFSLAAPESSPHPAHSQVVSTGYSRHVAVTVTRFLCGFLIPVFIITACYLTIVFKLQRNRLAKNKKPFKIIITIIITFFLCWCPYHTLYLLELHHTAVPSSVFSLGLPLATAVAIANSCMNPILYVFMGHDFRKFKVALFSRLANALSEDTGPSSYPSHRSFTKMSSLNEKASVNEKETSTL", "length": 371, "molWeight": 41815, "crc64": "CDBE19305244C0B3", "md5": "E085806B7B166710C5048D93BFDC48AA"}}
{"primaryAccession": "P97484", "text": "This is Leukocyte immunoglobulin-like receptor subfamily B member 3 protein, from Mouse, contains 841 amino acids, has 6 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [27, 116], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}, {"location": [118, 220], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}, {"location": [239, 297], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}, {"location": [308, 428], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}, {"location": [424, 513], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}, {"location": [537, 618], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "P97484", "organism_name": "Mouse", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3", "length": 841, "firstPublicDate": "2011-12-14", "FUNCTION": "May act as receptor for class I MHC antigens, Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor, Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM)", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {"Ig-like C2-type Immunoglobulin domain": 6}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSCTFTALLRLGLTLSLWIPVLTGSLPKPILRVQPDSVVSRRTKVTFLCEETIGANEYRLYKDGKLYKTVTKNKQKPENKAEFSFSNVDLSNAGQYRCSYSTQYKSSGYSDLLELVVTGHYWTPSLLAQASPVVTSGGYVTLQCESWHNDHKFILTVEGPQKLSWTQDSQYNYSTRKYHALFSVGPVTPNQRWICRCYSYDRNRPYVWSPPSESVELLVSGNLQKPTIKAEPGSVITSKRAMTIWCQGNLDAEVYFLHNEKSQKTQSTQTLQEPGNKGKFFIPSVTLQHAGQYRCYCYGSAGWSQPSDTLELVVTGIYEYYEPRLSVLPSPVVTAGGNMTLHCASDFPYDKFILTKEDKKFGNSLDTEHISSSGQYRALFIIGPTTPTHTGAFRCYGYYKNAPQLWSVPSALQQILISGLSKKPSLLTHQGHILDPGMTLTLQCFSDINYDRFALHKVGGADIMQHSSQQTDTGFSVANFTLGYVSSSTGGQYRCYGAHNLSSEWSASSEPLDILITGQLPLTPSLSVQPNHTVHSGETVSLLCWSMDSVDTFILSKEGSAQQPLRLKSKSHDQQSQAEFSMSAVTSHLSGTYRCYGAQDSSFYLLSSASAPVELTVSGPIETSTPPPTMSMPLGGLHMYLKALIGVSVAFILFLFIFIFILLRRRHRGKFRKDVQKEKDLQLSSGAEEPITRKGELQKRPNPAAATQEESLYASVEDMQTEDGVELNSWTPPEEDPQGETYAQVKPSRLRKAGHVSPSVMSREQLNTEYEQAEEGQGANNQAAESGESQDVTYAQLCSRTLRQGAAASPLSQAGEAPEEPSVYATLAAARPEAVPKDMEQ", "length": 841, "molWeight": 93054, "crc64": "33E9B3C51F44FF3C", "md5": "B50AEC402078CDA42613C05358EED399"}}
{"primaryAccession": "P97852", "text": "This is Peroxisomal multifunctional enzyme type 2 protein, from Rat, contains 735 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P97852", "organism_name": "Rat", "protein_name": "Peroxisomal multifunctional enzyme type 2", "length": 735, "firstPublicDate": "1997-11-01", "FUNCTION": "Bifunctional enzyme acting on the peroxisomal fatty acid beta-oxidation pathway, Catalyzes two of the four reactions in fatty acid degradation: hydration of 2-enoyl-CoA (trans-2-enoyl-CoA) to produce (3R)-3-hydroxyacyl-CoA, and dehydrogenation of (3R)-3-hydroxyacyl-CoA to produce 3-ketoacyl-CoA (3-oxoacyl-CoA), which is further metabolized by SCPx, Can use straight-chain and branched-chain fatty acids, as well as bile acid intermediates as substrates", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the short-chain dehydrogenases/reductases (SDR) family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVEEIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQRVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVIEGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLHKIDSEGISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDLKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSGELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAAVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFSARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVAAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNIMLSQKLQMILKDYAKL", "length": 735, "molWeight": 79428, "crc64": "E14F15FFD35FC7D8", "md5": "68F7D6388109D64920B1A050845E360F"}}
{"primaryAccession": "Q00805", "text": "This is Protein giant-lens protein, from Fruit fly, contains 444 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q00805", "organism_name": "Fruit fly", "protein_name": "Protein giant-lens", "length": 444, "firstPublicDate": "1993-04-01", "FUNCTION": "Regulates cell determination; development of ommatidia and optic lobe, Is a signaling molecule involved in the process of axon pathfinding in the eye, Part of the Ras pathway regulating programmed cell death in pupal eyes; activated by lozenge (lz), Antagonist for the Egfr receptor (gurken), Inhibits Egfr signaling without interacting directly with the receptor, but instead by sequestering the Egfr-activating ligand spitz (spi)", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPTTLMLLPCMLLLLLTAAAVAVGGTRLPLEVFEITPTTSTADKHKSLQYTVVYDAKDISGAAAATGVASSTVKPATEQLTVVSISSTAAAEKDLAESRRHARQMLQKQQQHRSIIGGKHGDRDVRILYQVGDSEEDLPVCAPNAVCSKIDLYETPWIERQCRCPESNRMPNNVIIHHHSHSSGSVDSLKYRNYYEREKMMQHKRMLLGEFQDKKFESLHMKKLMQKLGAVYEDDLDHLDQSPDYNDALPYAEVQDNEFPRGSAHMRHSGHRGSKEPATTFIGGCPSSLGVEDGHTIADKTRHYKMCQPVHKLPVCTHFRDYTWTLTTAAELNVTEQIVHCRCPRNSVTYLTKREPIGNGSPGYRYLFACSPLTRLRCQRKQPCKLFTVRKRQEFLDEVNINSLCQCPKGHRCPSHHTQSGVIAGESFLEDNIQTYSGYCMAND", "length": 444, "molWeight": 49924, "crc64": "10F7D17D4ACDBC00", "md5": "5832E33DCA984B8DC32D1DB1C806B1E5"}}
{"primaryAccession": "Q01081", "text": "This is Splicing factor U2AF 35 kDa subunit protein, from Human, contains 240 amino acids, has 2 C3H1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [12, 40], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [149, 176], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "Q01081", "organism_name": "Human", "protein_name": "Splicing factor U2AF 35 kDa subunit", "length": 240, "firstPublicDate": "1993-04-01", "FUNCTION": "Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection, Recruits U2 snRNP to the branch point, Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the splicing factor SR family", "domain_description": {"C3H1-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF", "length": 240, "molWeight": 27872, "crc64": "3DA130DCE0B953F6", "md5": "973FCEA5D4CFCCB4F1016E86EEB3E4F1"}}
{"primaryAccession": "Q01329", "text": "This is Pre-tRNA-processing protein PTA1 protein, from Baker's yeast, contains 785 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q01329", "organism_name": "Baker's yeast", "protein_name": "Pre-tRNA-processing protein PTA1", "length": 785, "firstPublicDate": "1993-04-01", "FUNCTION": "Essential in pre-tRNA processing, Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB, Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSAEMEQLLQAKTLAMHNNPTEMLPKVLETTASMYHNGNLSKLKLPLAKFFTQLVLDVVSMDSPIANTERPFIAAQYLPLLLAMAQSTADVLVYKNIVLIMCASYPLVLDLVAKTSNQEMFDQLCMLKKFVLSHWRTAYPLRATVDDETDVEQWLAQIDQNIGVKLATIKFISEVVLSQTKSPSGNEINSSTIPDNHPVLNKPALESEAKRLLDMLLNYLIEEQYMVSSVFIGIINSLSFVIKRRPQTTIRILSGLLRFNVDAKFPLEGKSDLNYKLSKRFVERAYKNFVQFGLKNQIITKSLSSGSGSSIYSKLTKISQTLHVIGEETKSKGILNFDPSKGNSKKTLSRQDKLKYISLWKRQLSALLSTLGVSTKTPTPVSAPATGSSTENMLDQLKILQKYTLNKASHQGNTFFNNSPKPISNTYSSVYSLMNSSNSNQDVTQLPNDILIKLSTEAILQMDSTKLITGLSIVASRYTDLMNTYINSVPSSSSSKRKSDDDDDGNDNEEVGNDGPTANSKKIKMETEPLAEEPEEPEDDDRMQKMLQEEESAQEISGDANKSTSAIKEIAPPFEPDSLTQDEKLKYLSKLTKKLFELSGRQDTTRAKSSSSSSILLDDDDSSSWLHVLIRLVTRGIEAQEASDLIREELLGFFIQDFEQRVSLIIEWLNEEWFFQTSLHQDPSNYKKWSLRVLESLGPFLENKHRRFFIRLMSELPSLQSDHLEALKPICLDPARSSLGFQTLKFLIMFRPPVQDTVRDLLHQLKQEDEGLHKQCDSLLDRLK", "length": 785, "molWeight": 88473, "crc64": "E2AB1F468B7BC8D0", "md5": "8EAE503CFFE313AC6789557CF5F6A1A4"}}
{"primaryAccession": "Q02040", "text": "This is A-kinase anchor protein 17A protein, from Human, contains 695 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02040", "organism_name": "Human", "protein_name": "A-kinase anchor protein 17A", "length": 695, "firstPublicDate": "1995-02-01", "FUNCTION": "Splice factor regulating alternative splice site selection for certain mRNA precursors, Mediates regulation of pre-mRNA splicing in a PKA-dependent manner", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAATIVHDTSEAVELCPAYGLYLKPITKMTISVALPQLKQPGKSISNWEVMERLKGMVQNHQFSTLRISKSTMDFIRFEGEVENKSLVKSFLACLDGKTIKLSGFSDILKVRAAEFKIDFPTRHDWDSFFRDAKDMNETLPGERPDTIHLEGLPCKWFALKESGSEKPSEDVLVKVFEKFGEIRNVDIPMLDPYREEMTGRNFHTFSFGGHLNFEAYVQYREYMGFIQAMSALRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPDDSHTHDELGVAHADLLQPVLDILQTVSSGCVSATTLHPLGGQPPAGAPKESPAHPEADGAPKSVNGSVAEEAPCKEVQSSCRVVPEDGSPEKRCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRATGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSHSKDRHRRERSRERRGSASRKHSRHRRRSERSRSRSPSRHRSTWNR", "length": 695, "molWeight": 80735, "crc64": "639E88ECA8006CF2", "md5": "BBF62887225273D35FFAC638C353A143"}}
{"primaryAccession": "Q02127", "text": "This is Dihydroorotate dehydrogenase (quinone), mitochondrial protein, from Human, contains 395 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02127", "organism_name": "Human", "protein_name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "length": 395, "firstPublicDate": "1993-07-01", "FUNCTION": "Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor, Required for UMP biosynthesis via de novo pathway", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the dihydroorotate dehydrogenase family, Type 2 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAWRHLKKRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR", "length": 395, "molWeight": 42867, "crc64": "072C3169E78C6440", "md5": "4037F3BEB1E0BA96339D591B10E5ED99"}}
{"primaryAccession": "Q02353", "text": "This is Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 protein, from Rat, contains 882 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02353", "organism_name": "Rat", "protein_name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1", "length": 882, "firstPublicDate": "1993-07-01", "FUNCTION": "Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate (PubMed:1379236, PubMed:3422231, PubMed:8483907, PubMed:9890952), Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis (PubMed:1379236, PubMed:3422231), Plays a role in determining the extent and pattern of sulfation of heparan sulfate, Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response (By similarity), Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the sulfotransferase 1 family, NDST subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPALACLRRLCRHLSPQAVLFLLFVFCLFSVFVSAYYLYGWNRGLEPSADASESDCGDPPPVAPSRLLPIKPVQAVAPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRTHIPNFTFNLGYSGKFFHTGTDAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWNIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISVFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGPDASSKLRALQNRCLVPGWYATHIERWLSAFHANQILVLDGKLLRTEPAKVMDTVQKFLGVTSTVDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNTR", "length": 882, "molWeight": 100785, "crc64": "F3AB9263EF6E4345", "md5": "910A03D466CF1C21612B01A136E31D3E"}}
{"primaryAccession": "Q02457", "text": "This is Protein TBF1 protein, from Baker's yeast, contains 562 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02457", "organism_name": "Baker's yeast", "protein_name": "Protein TBF1", "length": 562, "firstPublicDate": "1993-07-01", "FUNCTION": "Binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length, Involved in the regulation of gene expression, 52 binding sites have been identified, distributed over 15 chromosomes, A member of the general regulatory factors (GRFs) which act as genome partitioners, Acts as a chromatin insulator which are known as STARs (Subtelomeric anti-silencing region), STARs prevent negative or positive transcription influence by extending across chromatin to a promoter", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDSQVPNNNESLNRFNDIIQSLPARTRLTICSLCLLDNISTQLLRFLILNANSPNIIAVLTDQTAFLSSGETEIFQTLVKLFKQIRMIYHTRSPLLSVHDVAPGLWFPNSPPPLILRGHEAFIITAIRKANLLTFLLTSLNCLNYGFELLQSIFLDIFCPNTNTVGNNSLEQSGKFLKSQAILYLDLKTQAYIAGLKEFQDETNEISLEKKQELLDLIFPSNLADILVQRRTGDSGDITLLTPSEKDFVERCDRRRENLKIVQDFNSLTQSYEWAQFIRELLDYCNKNMGLIIWGRKGRGKSPLYDFDVNEFDPQVLFSTGTRTVEFMDDQNQPSSASAFLSTARPNHYSTHTPTTDVSSKNPAITQSIVDAAVAASMSNSSSGPHSSHNNSSNSNNNGSIGLRKPKAKRTWSKEEEEALVEGLKEVGPSWSKILDLYGPGGKITENLKNRTQVQLKDKARNWKLQYLKSGKPLPDYLIKVTGNLEKIYKAKKKFSQSPNSSTIMEQNLSQHPSSAASATEDTQTHQEDSHGQNSDNMPSNGLFGNSTSDNTGFDPHLEDGM", "length": 562, "molWeight": 62824, "crc64": "2340F086468EC54F", "md5": "D3D86C6B9412F4CE9F53C6DAB3C6CD14"}}
{"primaryAccession": "Q02775", "text": "This is Pre-mRNA-splicing factor SLU7 protein, from Baker's yeast, contains 382 amino acids, has 1 CCHC-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [120, 137], "description": "CCHC-type", "keyword_description": "Zinc finger", "textural_description": "CCHC-type Zinc finger"}], "meta_data": {"primaryAccession": "Q02775", "organism_name": "Baker's yeast", "protein_name": "Pre-mRNA-splicing factor SLU7", "length": 382, "firstPublicDate": "1993-07-01", "FUNCTION": "Essential protein involved in the second catalytic step of pre-mRNA splicing, Involved in the selection of 3'-type splice sites; this selection could be done via a 3'-splice site-binding factor, PRP16", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SLU7 family", "domain_description": {"CCHC-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNNNSRNNENRSTINRNKRQLQQAKEKNENIHIPRYIRNQPWYYKDTPKEQEGKKPGNDDTSTAEGGEKSDYLVHHRQKAKGGALDIDNNSEPKIGMGIKDEFKLIRPQKMSVRDSHSLSFCRNCGEAGHKEKDCMEKPRKMQKLVPDLNSQKNNGTVLVRATDDDWDSRKDRWYGYSGKEYNELISKWERDKRNKIKGKDKSQTDETLWDTDEEIELMKLELYKDSVGSLKKDDADNSQLYRTSTRLREDKAAYLNDINSTESNYDPKSRLYKTETLGAVDEKSKMFRRHLTGEGLKLNELNQFARSHAKEMGIRDEIEDKEKVQHVLVANPTKYEYLKKKREQEETKQPKIVSIGDLEARKVDGTKQSEEQRNHLKDLYG", "length": 382, "molWeight": 44637, "crc64": "6405458FC367A7D3", "md5": "FA7A37A485A8397819988C9BEB9F1FEB"}}
{"primaryAccession": "Q02953", "text": "This is Heat shock factor protein protein, from Fission yeast, contains 609 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02953", "organism_name": "Fission yeast", "protein_name": "Heat shock factor protein", "length": 609, "firstPublicDate": "1994-02-01", "FUNCTION": "DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription, Also required for growth at normal temperatures", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the HSF family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIQTASTISSNGGTNQGMESSSANSPEMNGTQNSMSVGMSGSGSSQNRKITQFSNKLYNMVNDSSTDSLIRWSDRGDSFLVIGHEDFAKLVLPRYFKHNNFSSFVRQLNMYGFHKVPHIQQGVLQSDSPNELLEFANPNFQRDQPELLCLVTRKKAGSQPVEESNTSLDMSTISSELQNIRIQQMNLSNELSRIQVDNAALWQENMENRERQRRHQETIDKILRFLASVYLDGKQKPPSKVMPKSRRLLLEAKYPTVSPTNEPSAHSRPSPQGTTANSSSASISSLHNTTPDGEGKYRSVQNGRALNYVSSFNSDSHSPKDYISQSYTNEPGLKKESADSFNNSIDSYISPNQSPNTDVPSLNRDDTTDPKVVNTGDIINMLDDANSIEGSNMNSLSPLLFDYPNSLYPVNNTSSEQHHNSYRGSVSNSQPSGNLSESTNLQPVQPVDYMSNSNPSYGSYNAEDQLTNFHPGYAMDQKRISKLSDGITKQDQNIQALADILGIPLGDGKIDDAGFSANSPTNLNLPVSSDLDSVLNIPPNEDVFPDSNPVFDEFTNISNLTSPIEASNGNTFGSNPVSLPNQQKSVNPSLMTVSSPRQVRKKRKSSIGA", "length": 609, "molWeight": 66947, "crc64": "CE1F7A87D8CBF50A", "md5": "544A1E340B090BBDAB1D32339DBF9D38"}}
{"primaryAccession": "Q03178", "text": "This is Cell wall mannoprotein PIR1 protein, from Baker's yeast, contains 341 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03178", "organism_name": "Baker's yeast", "protein_name": "Cell wall mannoprotein PIR1", "length": 341, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the outer cell wall layer, Required for stability of the cell wall and for optimal growth, Required for resistance against several antifungal and cell wall-perturbing agents and for tolerance to heat shock", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the PIR protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQYKKSLVASALVATSLAAYAPKDPWSTLTPSATYKGGITDYSSTFGIAVEPIATTASSKAKRAAAISQIGDGQIQATTKTTAAAVSQIGDGQIQATTKTKAAAVSQIGDGQIQATTKTTSAKTTAAAVSQIGDGQIQATTKTKAAAVSQIGDGQIQATTKTTAAAVSQIGDGQIQATTKTTAAAVSQIGDGQIQATTNTTVAPVSQITDGQIQATTLTSATIIPSPAPAPITNGTDPVTAETCKSSGTLEMNLKGGILTDGKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITPEGNLAIGDQDTFYQCLSGNFYNLYDEHIGTQCNAVHLQAIDLLNC", "length": 341, "molWeight": 34622, "crc64": "15F0736244769C12", "md5": "226ACB0472E7F1A270CB72229BEBD9FF"}}
{"primaryAccession": "Q03180", "text": "This is Cell wall mannoprotein PIR3 protein, from Baker's yeast, contains 325 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03180", "organism_name": "Baker's yeast", "protein_name": "Cell wall mannoprotein PIR3", "length": 325, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the outer cell wall layer, Required for stability of the cell wall and for optimal growth, Required for resistance against several antifungal and cell wall-perturbing agents", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the PIR protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQYKKPLVVSALAATSLAAYAPKDPWSTLTPSATYKGGITDYSSSFGIAIEAVATSASSVASSKAKRAASQIGDGQVQAATTTAAVSKKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAASQISDGQVQATTSTKAAASQITDGQIQASKTTSGASQVSDGQVQATAEVKDANDPVDVVSCNNNSTLSMSLSKGILTDRKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITPEGNLALGDQDTFYQCLSGDFYNLYDKHIGSQCHEVYLQAIDLIDC", "length": 325, "molWeight": 33004, "crc64": "7B5670510F8FD1A1", "md5": "EF0AA1AC11B990BB7EAD9477421F1B1D"}}
{"primaryAccession": "Q03406", "text": "This is DNA replication complex GINS protein SLD5 protein, from Baker's yeast, contains 294 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03406", "organism_name": "Baker's yeast", "protein_name": "DNA replication complex GINS protein SLD5", "length": 294, "firstPublicDate": "2005-03-15", "FUNCTION": "Required for DNA replication, Functions as part of the GINS complex which plays an essential role in the initiation of DNA replication by binding to DNA replication origins and facilitating the assembly of the DNA replication machinery", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the GINS4/SLD5 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDINIDDILAELDKETTAVDSTKITQGSSSTTHRDANTIVGSSLDLNDKTQIYVSPQQDFSDLMKSWKNERCSPELLPYPHQLMKRLLNRISMQSQLIENISMGFLDMQNASNANPPMPNESKLPLLCMETELERLKFVIRSYIRCRLSKIDKFSLYLRQLNEDENSLISLTDLLSKDEIKYHDTHSLIWLKLVNDSILKYMPEELQAINDTEGSVNMIDEPDWNKFVFIHVNGPPDGKWNEDPLLQENEFGKPCYTVTIPDLKEEVELTIGSIYVMRYEVIRDLLRDDKVALI", "length": 294, "molWeight": 33948, "crc64": "7EC516ADAD9900DD", "md5": "73AC6A8F23E939E4B8ADFACF1B837F10"}}
{"primaryAccession": "Q03431", "text": "This is Parathyroid hormone/parathyroid hormone-related peptide receptor protein, from Human, contains 593 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03431", "organism_name": "Human", "protein_name": "Parathyroid hormone/parathyroid hormone-related peptide receptor", "length": 593, "firstPublicDate": "1993-10-01", "FUNCTION": "Receptor for parathyroid hormone and for parathyroid hormone-related peptide, The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKPGTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM", "length": 593, "molWeight": 66361, "crc64": "DA1400640A6C7F2B", "md5": "B64BFC5A79649291E1945398D4EB9A98"}}
{"primaryAccession": "Q03445", "text": "This is Glutamate receptor 1 protein, from Fruit fly, contains 991 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03445", "organism_name": "Fruit fly", "protein_name": "Glutamate receptor 1", "length": 991, "firstPublicDate": "1998-07-15", "FUNCTION": "Receptor for glutamate, L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system, The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity), Forms ligand-gated ion channels which are activated by kainate", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glutamate-gated ion channel (TC 1,A,10,1) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MHSRLKFLAYLHFICASSIFWPEFSSAQQQQQTVSLTEKIPLGAIFEQGTDDVQSAFKYAMLNHNLNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLAPSSGLLDFAISMRPDYHQAIIDTIQYYGWQSIIYLYDSHDGLLRLQQIYQELKPGNETFRVQMVKRIANVTMAIEFLHTLEDLGRFSKKRIVLDCPAEMAKEIIVQHVRDIKLGRRTYHYLLSGLVMDNHWPSDVVEFGAINITGFRIVDSNRRAVRDFHDSRKRLEPSGQSQSQNAGGPNSLPAISAQAALMYDAVFVLVEAFNRILRKKPDQFRSNHLQRRSHGGSSSSSATGTNESSALLDCNTSKGWVTPWEQGEKISRVLRKVEIDGLSGEIRFDEDGRRINYTLHVVEMSVNSTLQQVAEWRDDAGLLPLHSHNYASSSRSASASTGDYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVKQTPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGATLSEPQAHVPPVPPNEFTMLNSFWYSLAAFMQQGCDITPPSIAGRIAAAVWWFFTIILISSYTANLAAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQHHSVHTYDEGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKWWFDKTECNLDQETSTPNELSLSNVAGIYYILIGGLLLAVIVAIMEFFCRNKTPQLKSPGSNGSAGGVPGMLASSTYQRDSLSDAIMHSQAKLAMQASSEYDERLVGVELASNVRYQYSM", "length": 991, "molWeight": 111668, "crc64": "C8917868ABA06F98", "md5": "5B8E8BEC7540C3FE052E81C2F9A8EEF9"}}
{"primaryAccession": "Q03529", "text": "This is Ceramide very long chain fatty acid hydroxylase SCS7 protein, from Baker's yeast, contains 384 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03529", "organism_name": "Baker's yeast", "protein_name": "Ceramide very long chain fatty acid hydroxylase SCS7", "length": 384, "firstPublicDate": "1997-11-01", "FUNCTION": "Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids (PubMed:9353282, PubMed:9368039, PubMed:26977056, PubMed:9559540, PubMed:16652392, PubMed:19074599), Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2 (PubMed:9368039, PubMed:26977056)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the sterol desaturase family, SCS7 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSTNTSKTLELFSKKTVQEHNTANDCWVTYQNRKIYDVTRFLSEHPGGDESILDYAGKDITEIMKDSDVHEHSDSAYEILEDEYLIGYLATDEEAARLLTNKNHKVEVQLSADGTEFDSTTFVKELPAEEKLSIATDYSNDYKKHKFLDLNRPLLMQILRSDFKKDFYVDQIHRPRHYGKGSAPLFGNFLEPLTKTAWWVVPVAWLPVVVYHMGVALKNMNQLFACFLFCVGVFVWTLIEYGLHRFLFHFDDWLPESNIAFATHFLLHGCHHYLPMDKYRLVMPPTLFVILCAPFYKLVFALLPLYWAYAGFAGGLFGYVCYDECHFFLHHSKLPPFMRKLKKYHLEHHYKNYQLGFGVTSWFWDEVFGTYLGPDAPLSKMKYE", "length": 384, "molWeight": 44881, "crc64": "DF4BA5F2E0EA2218", "md5": "9307C7A6E80ED39D8B6529329FEE1819"}}
{"primaryAccession": "Q03774", "text": "This is tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82 protein, from Baker's yeast, contains 444 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03774", "organism_name": "Baker's yeast", "protein_name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82", "length": 444, "firstPublicDate": "2003-06-27", "FUNCTION": "Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay, In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WD repeat TRM82 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVIHPLQNLLTSRDGSLVFAIIKNCILSFKYQSPNHWEFAGKWSDDFDKIQESRNTTAKEQQGQSSENENENKKLKSNKGDSIKRTAAKVPSPGLGAPPIYSYIRNLRLTSDESRLIACADSDKSLLVFDVDKTSKNVLKLRKRFCFSKRPNAISIAEDDTTVIIADKFGDVYSIDINSIPEEKFTQEPILGHVSMLTDVHLIKDSDGHQFIITSDRDEHIKISHYPQCFIVDKWLFGHKHFVSSICCGKDYLLLSAGGDDKIFAWDWKTGKNLSTFDYNSLIKPYLNDQHLAPPRFQNENNDIIEFAVSKIIKSKNLPFVAFFVEATKCIIILEMSEKQKGDLALKQIITFPYNVISLSAHNDEFQVTLDNKESSGVQKNFAKFIEYNLNENSFVVNNEKSNEFDSAIIQSVQGDSNLVTKKEEIYPLYNVSSLRKHGEHYS", "length": 444, "molWeight": 50488, "crc64": "F1E0847F44376969", "md5": "C65BDB5920FAA6944FC7FE72087120BD"}}
{"primaryAccession": "Q03833", "text": "This is Transcriptional activator/repressor GIS1 protein, from Baker's yeast, contains 894 amino acids, has 1 C2H2-type Zinc finger, has 1 C2H2-type 2; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [828, 851], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [857, 882], "description": "C2H2-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q03833", "organism_name": "Baker's yeast", "protein_name": "Transcriptional activator/repressor GIS1", "length": 894, "firstPublicDate": "2004-08-16", "FUNCTION": "Transcription factor involved in the regulation of gene expression upon nutrient starvation, Recognizes and binds to the post-diauxic-shift element 5'-T[AT]AGGGAT-3' in the promoter region, Can act as a transcriptional activator (e,g, of stress genes like SSA3, HSP12 and HSP26) as well as a repressor (e,g, of pyrophosphate phosphatase DPP1), GIS1 also acts as a DNA damage-responsive transcriptional repressor of photolyase PHR1", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 1, "C2H2-type 2; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEIKPVEVIDGVPVFKPSMMEFANFQYFIDEITKFGIENGIVKVIPPKEWLELLEGSPPAESLKTIQLDSPIQQQAKRWDKHENGVFSIENEYDNKSYNLTQWKNLAESLDSRISQGDFNDKTLKENCRVDSQQDCYDLAQLQILESDFWKTIAFSKPFYAVDENSSIFPYDLTLWNLNNLPDSINSSNRRLLTGQSKCIFPWHLDEQNKCSINYLHFGAPKQWYSIPSANTDQFLKILSKEPSSNKENCPAFIRHQNIITSPDFLRKNNIKFNRVVQFQHEFIITFPYCMYSGFNYGYNFGESIEFILDQQAVVRKQPLKCGCGNKKEERKSGPFSNLSYDSNESEQRGSITDNDNDLFQKVRSFDELLNHSSQELQNLEDNKNPLFSNINMNRPQSSSLRSTTPNGVNQFLNMNQTTISRISSPLLSRMMDLSNIVEPTLDDPGSKFKRKVLTPQLPQMNIPSNSSNFGTPSLTNTNSLLSNITATSTNPSTTTNGSQNHNNVNANGINTSAAASINNNISSTNNSANNSSSNNNVSTVPSSMMHSSTLNGTSGLGGDNDDNMLALSLATLANSATASPRLTLPPLSSPMNPNGHTSYNGNMMNNNSGNGSNGSNSYSNGVTTAAATTTSAPHNLSIVSPNPTYSPNPLSLYLTNSKNPLNSGLAPLSPSTSNIPFLKRNNVVTLNISREASKSPISSFVNDYRSPLGVSNPLMYSSTINDYSNGTGIRQNSNNINPLDAGPSFSPLHKKPKILNGNDNSNLDSNNFDYSFTGNKQESNPSILNNNTNNNDNYRTSSMNNNGNNYQAHSSKFGENEVIMSDHGKIYICRECNRQFSSGHHLTRHKKSVHSGEKPHSCPRCGKRFKRRDHVLQHLNKKIPCTQEMENTKLAES", "length": 894, "molWeight": 99481, "crc64": "06F9F2B7F485DF88", "md5": "78D84A1B8C9DBA196D0B778C672832EA"}}
{"primaryAccession": "Q04235", "text": "This is tRNA wybutosine-synthesizing protein 2 protein, from Baker's yeast, contains 462 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q04235", "organism_name": "Baker's yeast", "protein_name": "tRNA wybutosine-synthesizing protein 2", "length": 462, "firstPublicDate": "1997-11-01", "FUNCTION": "S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway, Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA, Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the class I-like SAM-binding methyltransferase superfamily, TRM5/TYW2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSDETMPVEFLVSDKRLLKTIKVKLETNGLFVTPIYSDNDNKVIKSSIEDLNHPLAVEINNIAGVKARFHESGNLERSEGHLKHQSNSITEFTKSFLKDHGLANDKIFLSHLLDHLPLKYTIYPPVVLFNNSTVRSFNHPIWQKAFQLKLFDPNEYYRELLCFLSPGKPSKGTSLHPNNRLLTHLAINNPITEADVLRRPFNIQPLYGKLIDDSILDDNDNTLWENPSQEQLNSSIWCKVIQNGVTQIWSPVFTMFSRGNIKEKKRVLTTFPDICNNDVVDLYAGIGYFTFSYLTKGARTLFAFELNPWSVEGLKRGLKANGFNKSGNCHVFQESNEMCVQRLTEFLSQNPGFRLRIRHINLGLLPSSKQGWPLAIKLIYLQGASLEKVTMHIHENVHIDAIEDGSFEKNVIVELDAINESIALIRNRGIKLQFVRSKLERIKTFAPDIWHVCVDVDVIVST", "length": 462, "molWeight": 52726, "crc64": "C581EF189A7D733C", "md5": "1F2F17CC1030C9A9E53438207CEFB36D"}}
{"primaryAccession": "Q04924", "text": "This is Glucosidase 2 subunit beta protein, from Baker's yeast, contains 702 amino acids, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q04924", "organism_name": "Baker's yeast", "protein_name": "Glucosidase 2 subunit beta", "length": 702, "firstPublicDate": "2006-07-11", "FUNCTION": "Subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins, Specifically required for the cleavage of the final glucose", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVSMFSLFLLLIEQSPLVASLQQSQRHIVGVPWEKQHLYDSNEPDLTKWHCLNHEDIVLDISQINDGVCDCPDGSDEPGSAACVEDIFKSVAEGGGKVNKYFYCDNKGFIPRYIRKSEVADGICDCCDCSDELLSGYELFDAGSNCSQLKNEFDIMASKELSSYREGKEALEELERKYGTKEEAITRGNCLEEDKEKASAEIKVLSNRLSENRAKLEQLRGEYFNQLSHDPILYQFEQLNSTRLGSDILTSFTMVSRVSKGYQDIFKILSDLSEAYTPSLNDKVVNDNIKKFRKVRRRAEKAKINADSKIDDEQADNLYLYFTEEVPQIFLKRESENTLRYVIGKSNFVQALVEGKINYTNDILEYIREFRLIMDDISQNYNVNFQDAGVKSAVDSYKNYLGEYGELAELEPAHPSESLLRSLSEVTSFVNENAPKVLPPDAVESEQDTNSDHIGTSGDLRNKLKEILSKLNIFSSRKDLVSLEKRFRSCESQVSLLENELKQKMDYKKLLDETEDEGTNSTAGNLTELLELMGSQSYCLDDILDNYVYTICFQRPMTEGVIYQAEDKVDGKKVLIGRFKTSGFNVDLNMEKYAEHLKATYDEKSDLISNLAAIQDDDGNMQHYVFGNLNELNNGLVLEYENGDQCWNGPRRSATVFVRCSDKFKIRSVHEATKCNYIFDVVGPLGCNKTFEYEPPKFNLSE", "length": 702, "molWeight": 79907, "crc64": "237D9756939D57DD", "md5": "A87B69A63B393807BA744B2C7D08A367"}}
{"primaryAccession": "Q05021", "text": "This is Transcription initiation factor TFIID subunit 7 protein, from Baker's yeast, contains 590 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05021", "organism_name": "Baker's yeast", "protein_name": "Transcription initiation factor TFIID subunit 7", "length": 590, "firstPublicDate": "1997-11-01", "FUNCTION": "Functions as a component of the DNA-binding general transcription factor complex TFIID, Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation, TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription, TAF7 is responsible for the recruitment of BDF1 to TATA element containing promoters", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TAF7 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAVIRIKKPRGPGEKDQPLEGEPKLKRIRIKTKVTDEDIKPKPKLKINLKKKKESADGKEKKNSLKLKLNLKKNEEPVKKIHKAPKLRLKPIRIPGEAYDSEASDIEDDPLIESGVILRILPDIQLEFVKNSLESGDYSGISIKWKNERHAVVTINDVMYGAILVDLPTVIEVNKSVDRKNLLKTFDVSQMLLCIRPIQEEEEVYALEAPDTEDLVVKHFEGIEDEIWENKETFLKGYNGAPLSDMEAKHLKEIALKGYDYKHGISPPLYNVRNRRFRRKMDPNEIDYVEKVVDMLLKQDKQAEEVSYDLVDKSELQARQERVSSWENFKEEPGEPLSRPALKKEEIHTIASAVGKQGAEEEGEEGMEEEEEEDLDLGAAFESEEEGSGAEGDKEQQQEEVGDEVDQDTGGEDDDDDDDGDIEAAGGESESDDEKDENRQHTELLADELNELETTLAHTKHKLSKATNPLLKSRFIDSIKKLEKEAELKRKQLQQTEDSVQKQHQHRSDAETANNVEEEEEEEEEEEEEDEVDEDEEDDEENDEDEDNVHEREHIQENKVVRELDEAPAEETLDQNDLDMMMLFGAEGDE", "length": 590, "molWeight": 67555, "crc64": "C014E7419B0B1C61", "md5": "EFFF98677379635B9F177973E3B9EBD6"}}
{"primaryAccession": "Q05031", "text": "This is Mannan endo-1,6-alpha-mannosidase DFG5 protein, from Baker's yeast, contains 458 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05031", "organism_name": "Baker's yeast", "protein_name": "Mannan endo-1,6-alpha-mannosidase DFG5", "length": 458, "firstPublicDate": "1997-11-01", "FUNCTION": "Required for normal synthesis of the cell wall", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glycosyl hydrolase 76 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MIVNISAKMILSICFTFLSFFKATHAMDLDTTSKTSICDATALIQGGMLDYYEGTRYGGTVGMFQSPYYWWHAGEAFGGMLENWFLCENDTYQELLYDALLAQTGSNYDYIPSNQTMVEGNDDQGIWGITVMGAVERNFTDPGDGKPGWLAMVQAVFNTMYSRWDSEHCGGGLRWQIFTWNSGYNYKNTVSNACLFQIAARLGRYTGNTTYLEVAEQVFDWLVDVGYVVLNDTANVFDGAEIDTNCTDITKIEWTYNHGIVLGGLAYMYNATNGTGEWETSLTKILNGAKSYFFKDSIMYESACQDYGTCNTDQRTFKSIFSRMLGLTSVMAPFTRDTIDDLIKTSAEAAAKSCNGGTDGHTCGLNWQKQTNDGYYGLGEQMSALEVIQNLLIHDRPAPYKEDNGGTSKGDANAGMNSSTTNVLQNNLNIKKGDRAGAAIITAVILSVLTGGAVWMLF", "length": 458, "molWeight": 50541, "crc64": "908D7E672333EC03", "md5": "92EF37F6BA4C2941B1A82713A5F9E769"}}
{"primaryAccession": "Q05123", "text": "This is Actin-like protein ARP9 protein, from Baker's yeast, contains 467 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05123", "organism_name": "Baker's yeast", "protein_name": "Actin-like protein ARP9", "length": 467, "firstPublicDate": "1997-11-01", "FUNCTION": "Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning, RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA, The reaction requires ATP and involves an activated RSC-nucleosome intermediate, Remodeling reaction also involves DNA translocation, DNA twist and conformational change, As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton, This subunit is involved in transcriptional regulation, Heterodimer of ARP9 and ARP7 functions with HMG box proteins to facilitate proper chromatin architecture, Heterodimer formation is necessary for assembly into RSC complex, Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, is required for the positive and negative regulation of gene expression of a large number of genes, It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the actin family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAPFRQDSILIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNKAELIKPIQNGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAELSNIPLLLITHHSWSQSDLEIITQYVFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDSLKKLLPQWDDDQIESLKKSPIFEVLSDDAKKLSSFDFGNENEDEDEGTLNVAEIITSGRDTREVLEERERGQKVKNVKNSDLEFNTFWDEKGNEIKVGKQRFQGCNNLIKNISNRVGLTLDNIDDINKAKAVWENIIIVGGTTSISGFKEALLGQLLKDHLIIEPEEEKSKREEEAKSVLPAATKKKSKFMTNSTAFVPTIEYVQCPTVIKLAKYPDYFPEWKKSGYSEIIFLGAQIVSKQIFTHPKDTFYITREKYNMKGPAALWDVQF", "length": 467, "molWeight": 53074, "crc64": "EE1AB154A906420E", "md5": "92E366EB0430EC972E0AD578AE3B7C77"}}
{"primaryAccession": "Q05201", "text": "This is Developmental protein eyes absent protein, from Fruit fly, contains 766 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05201", "organism_name": "Fruit fly", "protein_name": "Developmental protein eyes absent", "length": 766, "firstPublicDate": "1994-06-01", "FUNCTION": "Tyrosine phosphatase thought to play a role in transcription regulation during organogenesis through its intrinsic protein phosphatase activity (PubMed:14628052, PubMed:14628053), The phosphatase activity was shown in vitro, Appears to function together with So and Dac in eye development (PubMed:9428512, PubMed:9428513), Required for the survival of eye progenitor cells at a critical stage in morphogenesis (PubMed:8431945)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the HAD-like hydrolase superfamily, EYA family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVTLMPYNYAAPRCGLIDKMIEPKVKRPKTDHTDTHERNRLCNLSQQQQQQQPQQQQTHQQQQQQQQQSHQQSHSSTVLASNGPSSAGAGMGVGVGGGGGSGGGVGGGVGQCSPLGLPPQSQPLQPTIGSLASLSGHYSNGNANPNVNSSSCSLATASSFAQSAGSSFSTYQQAGGTSGGVSGEDGVVGGATVMSHWTHDGTGSSAAVKSESRSPGQVHASLDNGSVAGSNLYGCSSASNPLDGGAVAVNSSAVAAAAAAVYDGKHDYYYYNSMQQYTPPPFYSGYGTPYAAATAARQAKMEPGAAAAAAAYLTPSYAASGNNNSQLYSSPYAGYNNFGQQDYGGYYNEQYGNYYSPANYSPYAVSSPSSSASHGHGFHVAASSNLSESPTDTHSTTPVHQTTHSPHSPLPISPSTGSGIGPLGNVSAAAAAAALNSSGGSSVGTAGSGGVATSKTTPTGKTGRARGRRHQQPSPTRSTASDTGNSEAVKPPERVFVWDLDETLIIFHTLLSGSYANRYTKDHSSLMTIAFRMEEMVFNMADTHFFFNEIEECDQVHIDDVSSDDNGQDLSAYNFATDGFHTNTPPGAPPNLCLPTGVRGGVDWMRKLAFRYRKIKDIYNSYRGNVGTLLGPGKREAWLQIRSEIEVATDNWATLALKCLSMISQRENCVNVLVTSTQLAPALAKVLLFGLGGIFNIENIYSAHKIGHETCYERIVTRFGRKSTYVVIGDGNEEETAAKAMNFPFWRISAHSDIRALYTALDMGFL", "length": 766, "molWeight": 80657, "crc64": "3581C26AB1811E74", "md5": "10817F38BD8572C87781347743F9D716"}}
{"primaryAccession": "Q05949", "text": "This is Protein BUR2 protein, from Baker's yeast, contains 395 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05949", "organism_name": "Baker's yeast", "protein_name": "Protein BUR2", "length": 395, "firstPublicDate": "2006-01-10", "FUNCTION": "Component of the BUR kinase complex involved in transcription regulation, This complex phosphorylates 'Ser-120' of the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B, the localization of the PAF1 complex to the chromatin, and the silencing of telomeric-associated genes, Also required for histone H3 'Lys-4' trimethylation, May phosphorylate the 'Ser-5' of the RBP1 carboxy-terminal domain (CTD) repeats, Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase, Also required for vegetative growth itself, The kinase activity of the complex requires the presence of BUR2, Overexpression of BUR2 interferes with mitotic chromosome segregation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSATSSSGDVKKFQAVPKPTSNASPPPASSGFNARTLWPDLIETPENQWVFECKDIIEKIGTNGPIAVEIKKNMEKCLMYFYTLKKKLNLFDHTYTASCILFYRYWFIYGIPTAITECIHISQGILVTACKTMENNRPIEAYIKATCEFLMQNIPSLKSRTNIDKLKWEFRDKLVTNEKKILCLFGFDLNISNPKELIEEVFSGYYRFNRDHNLPENFKKAFPKILQESRNFMVQAVTQPVSLLCDGYTFIVLSLIYCGLEYKKLVDKDFRYPKNFFKDRFPIEVTPENFANIFTDYKLLEENFFNLKSNKGAKLQIDSSMIDSVIDESGDVENEVSEISDPFNYELIKSGEVKEEFLNHIETRVKDLLDKAKQESMKRKAKDPIRTPDAKKPKI", "length": 395, "molWeight": 45721, "crc64": "B317A7B429030FDF", "md5": "38DA8EA138664E8A3CC15046A3502300"}}
{"primaryAccession": "Q06224", "text": "This is Endoribonuclease YSH1 protein, from Baker's yeast, contains 779 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06224", "organism_name": "Baker's yeast", "protein_name": "Endoribonuclease YSH1", "length": 779, "firstPublicDate": "2006-01-10", "FUNCTION": "Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB, Has endonuclease activity", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MERTNTTTFKFFSLGGSNEVGRSCHILQYKGKTVMLDAGIHPAYQGLASLPFYDEFDLSKVDILLISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRWLLRDFVRVTSIGSSSSSMGTKDEGLFSDEDLVDSFDKIETVDYHSTVDVNGIKFTAFHAGHVLGAAMFQIEIAGLRVLFTGDYSREVDRHLNSAEVPPLSSNVLIVESTFGTATHEPRLNRERKLTQLIHSTVMRGGRVLLPVFALGRAQEIMLILDEYWSQHADELGGGQVPIFYASNLAKKCMSVFQTYVNMMNDDIRKKFRDSQTNPFIFKNISYLRNLEDFQDFGPSVMLASPGMLQSGLSRDLLERWCPEDKNLVLITGYSIEGTMAKFIMLEPDTIPSINNPEITIPRRCQVEEISFAAHVDFQENLEFIEKISAPNIILVHGEANPMGRLKSALLSNFASLKGTDNEVHVFNPRNCVEVDLEFQGVKVAKAVGNIVNEIYKEENVEIKEEIAAKIEPIKEENEDNLDSQAEKGLVDEEEHKDIVVSGILVSDDKNFELDFLSLSDLREHHPDLSTTILRERQSVRVNCKKELIYWHILQMFGEAEVLQDDDRVTNQEPKVKEESKDNLTNTGKLILQIMGDIKLTIVNTLAVVEWTQDLMNDTVADSIIAILMNVDSAPASVKLSSHSCDDHDHNNVQSNAQGKIDEVERVKQISRLFKEQFGDCFTLFLNKDEYASNKEETITGVVTIGKSTAKIDFNNMKILECNSNPLKGRVESLLNIGGNLVTPLC", "length": 779, "molWeight": 87674, "crc64": "901582F0C33AD6F7", "md5": "B6C2857F5ACAEFE0D2B008B5EC06FF02"}}
{"primaryAccession": "Q06385", "text": "This is Vacuolar protein sorting-associated protein 74 protein, from Baker's yeast, contains 345 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06385", "organism_name": "Baker's yeast", "protein_name": "Vacuolar protein sorting-associated protein 74", "length": 345, "firstPublicDate": "2004-07-19", "FUNCTION": "Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi, Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus, May also bind to the coatomer to regulate Golgi membrane trafficking, May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion, Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains, Involved in vacuolar protein sorting", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GOLPH3/VPS74 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSTLQRRRVNRADSGDTSSIHSSANNTKGDKIANIAVDGDDDNGTNKKIAYDPEESKLRDNINIPTLTLMEEVLLMGLRDREGYLSFWNDSISYALRGCIIIELALRGKIRILDDSARKRFDLSERLIEVIDSSKTGEVLLDETLQLMKNDEPLSISNWIDLLSGETWNLLKINYQLKQVRERLAKGLVDKGVLRTEMKNFFLFDMATHPIADASCKEAIKRRVLSVLVSRNMELSYNEYFPETTSFKIIRTLALICGSYGANVLENVLTTLEYEKRDKAISRAEEIMAQFSQYPFDLEKETELGVSVNLNKEVKEEIENNPGHDLQLEVIAGVFEVFSRMDMLL", "length": 345, "molWeight": 39287, "crc64": "9D111E5F894F3646", "md5": "B98EE1378CF580D160669EB3199F5A9D"}}
{"primaryAccession": "Q06488", "text": "This is Chromatin structure-remodeling complex subunit RSC2 protein, from Baker's yeast, contains 889 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06488", "organism_name": "Baker's yeast", "protein_name": "Chromatin structure-remodeling complex subunit RSC2", "length": 889, "firstPublicDate": "2001-01-11", "FUNCTION": "Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning, RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA, The reaction requires ATP and involves an activated RSC-nucleosome intermediate, Remodeling reaction also involves DNA translocation, DNA twist and conformational change, As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton, This subunit is involved in meiotic sporulation through regulating IME2 expression, and is also essential for 2-micron plasmid maintenance and for normal REP1 protein localization", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RSC1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMPDDNSNSSTQNSSALYKDLRKEYESLFTLKEDSGLEISPIFNVLPPKKDYPDYYAVIKNPVSFNTLKKRIPHYTDAQQFMNDVVQIPWNAKTYNTRDSGIYKYALVLEKYLKDTIYPNLKEKYPQLVYPDLGPLPDEPGYEEFQQKLREKAEEVARANAARAESSSSMNSTEAARRLRKTRTSVKRESEPGTDTNNDEDYEATDMDIDNPKDADFPDLIRKPLININPYTRKPLRDNRSTTPSHSGTPQPLGPRHRQVSRTQVKRGRPPIIDLPYIQRMKNVMKVLKKEVLDSGIGLTDLFERLPDRHRDANYYIMIANPISLQDINKKVKTRRYKTFQEFQNDFNLMLTNFRISHRGDPESIKISNILEKTFTSLARFELSKPDRSFIPEGELRYPLDEVIVNNISYHVGDWALLRNQNDPQKPIVGQIFRLWKTPDGKQWLNACWYYRPEQTVHRVDRLFYKNEVMKTGQYRDHLVSNLVGKCYVIHFTRYQRGNPDMKLEGPLFVCEFRYNESDKIFNKIRTWKACLPEEIRDLDEATIPVNGRKFFKYPSPIRHLLPANATPHDRVPEPTMGSPDAPPLVGAVYMRPKMQRDDLGEYATSDDCPRYIIRPNDSPEEGQVDIETGTITTNTPTANALPKTGYSSSKLSSLRYNRSSMSLENQNAIGQQQIPLSRVGSPGAGGPLTVQGLKQHQLQRLQQQQHQYQQQKRSQASRYNIPTIIDDLTSQASRGNLGNIMIDAASSFVLPISITKNVDVLQRTDLHSQTKRSGREEMFPWKKTKGEILWFRGPSVIVNERIINSGDPHLSLPLNRWFTTNKKRKLEYEEVEETMEDVTGKDKDDDGLEPDVENEKESLPGPFVLGLRPSAKFTAHRLSMLRPPSSSS", "length": 889, "molWeight": 102300, "crc64": "7867866FD973F188", "md5": "03C023E2500A12371E7311871E2C8D91"}}
{"primaryAccession": "Q06551", "text": "This is Palmitoyltransferase ERF2 protein, from Baker's yeast, contains 359 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06551", "organism_name": "Baker's yeast", "protein_name": "Palmitoyltransferase ERF2", "length": 359, "firstPublicDate": "2005-11-22", "FUNCTION": "The ERF2-SHR5 complex is a palmitoyltransferase specific for Ras proteins, Palmitoylates RAS2, which is required for its proper plasma membrane localization", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DHHC palmitoyltransferase family, ERF2/ZDHHC9 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MALVSRRSTRSESTSITKEEHTGEGSLTKLFFRWLVTLEGDQDINDGKGYISLPNVSNYIFFLGGRFRTVKGAKPLWLGVLLAIVCPMVLFSIFEAHKLWHTQNGYKVLVIFFYYFWVITLASFIRTATSDPGVLPRNIHLSQLRNNYQIPQEYYNLITLPTHSSISKDITIKYCPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRNYRFFLIFLLGAILSSVILLTNCAIHIARESGGPRDCPVAILLLCYAGLTLWYPAILFTYHIFMAGNQQTTREFLKGIGSKKNPVFHRVVKEENIYNKGSFLKNMGHLMLEPRGPSFVSARKPHEAGDWRFMDLSPAHSFEKIQKI", "length": 359, "molWeight": 41099, "crc64": "B1FF42A2370F064B", "md5": "226659507ADF8131FE1F9F464446099A"}}
{"primaryAccession": "Q06679", "text": "This is U3 small nucleolar RNA-associated protein 4 protein, from Baker's yeast, contains 776 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06679", "organism_name": "Baker's yeast", "protein_name": "U3 small nucleolar RNA-associated protein 4", "length": 776, "firstPublicDate": "2005-02-01", "FUNCTION": "Involved in nucleolar processing of pre-18S ribosomal RNA, Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSSLLSVLKEKSRSLKIRNKPVKMTSQERMIVHRCRFVDFTPATITSLAFSHKSNINKLTPSDLRLAIGRSNGNIEIWNPRNNWFQEMVIEGGKDRSIEGLCWSNVNGESLRLFSIGGSTVVTEWDLATGLPLRNYDCNSGVIWSISINDSQDKLSVGCDNGTVVLIDISGGPGVLEHDTILMRQEARVLTLAWKKDDFVIGGCSDGRIRIWSAQKNDENMGRLLHTMKVDKAKKESTLVWSVIYLPRTDQIASGDSTGSIKFWDFQFATLNQSFKAHDADVLCLTTDTDNNYVFSAGVDRKIFQFSQNTNKSQKNNRWVNSSNRLLHGNDIRAICAYQSKGADFLVSGGVEKTLVINSLTSFSNGNYRKMPTVEPYSKNVLVNKEQRLVVSWSESTVKIWTMGTDSSTEQNYKLVCKLTLKDDQNISTCSLSPDGQVLVVGRPSTTKVFHLQPVGNKLKVTKLDNDLLLRTSTKLVKFIDNSKIVICSCEDDVFIVDLESEEDEKPQEVELLEVTSTKSSIKVPYINRINHLEVDQNIAVISRGCGVVDILDLKARISKPLARLNNFITAVHINTSRKSVVVITADNKIYEFNMNLNSEAENEDSESVLTQWSKNNTDNLPKEWKTLKENCVGIFSDIENSSRLWFWGATWISRIDFDVDFPINKRRKQKKRTHEGLTITDESNFMNDEEDDEDDDIDMEISENLNVLLNQGNKIKSTDVQRNEESSGHFFFTDKYKPLLFVDLISSNELAIIERNPLTFHSKQKAFIQPKLVF", "length": 776, "molWeight": 87801, "crc64": "5D1C77899CABB40B", "md5": "FCC665BACBDBAAB4658E2CBFE6F70DC2"}}
{"primaryAccession": "Q07084", "text": "This is Osmolarity two-component system protein SSK1 protein, from Baker's yeast, contains 712 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q07084", "organism_name": "Baker's yeast", "protein_name": "Osmolarity two-component system protein SSK1", "length": 712, "firstPublicDate": "1997-11-01", "FUNCTION": "Final receptor of the SLN1-YPD1-SSK1 two-component regulatory system, which controls activity of the HOG1 pathway in response to changes in the osmolarity of the extracellular environment, Under normal osmotic conditions, maintained in a phosphorylated and inactive state by the phosphorelay intermediate protein YPD1, Under conditions of high osmolarity, the histidine kinase SLN1 is no longer active and the unphosphorylated form of SSK1 interacts with and activates SSK2 and SSK22, two MAPKKKs that further stimulate the PBS2-HOG1 MAPKK-MAPK cascade, Unphosphorylated SSK1 is subsequently degraded by the UBC7-dependent ubiquitin-proteasome system to down-regulate the HOG1 pathway after completion of the osmotic adaptation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLNSALLWKVWLRIDNSTDEVNQPIAVQFDEIDTVDDLKSRFFQKLSSTRWREINDNASIAIGLYAPKFDNQADNTSSNNTNDNSCRSKSNGAGSGANLSVNSNTKSSVSPTAGSFGLSKDLAKDRNVLQHPKPTQKRGALYDAFAAVPTVAATTNVDFPPNEAPMLSPQRPYSTSPKQFPATTKSPLLRFASVSPYPKFHSDNQIMASAGLTYVSPHNKNKYTRPLIRKGLNFTTESVNDCTYKIIFEPDELAINIYKELFGTMGSQPASQPLLIFSNVNLRQDVPPLDILNVVDYVPTNEEISQQKTQPTDHGAVGVFHLDDHISPGEQGLKQTIGDKADLKGKDGNSSPQEFKLITDEEQLRRASQELKDEEKDAESPWQAILLLPKGYKGGVDFRNKPVAHTDSSFNNEDTITHSELEVNTGSPSQESGSLNEAGIGITQPMSEVQRRKEDVTPASPILTSSQTPHYSNSLYNAPFAVSSPPDPLPNLFTTTSEKVFPKINVLIVEDNVINQAILGSFLRKHKISYKLAKNGQEAVNIWKEGGLHLIFMDLQLPVLSGIEAAKQIRDFEKQNGIGIQKSLNNSHSNLEKGTSKRFSQAPVIIVALTASNSQMDKRKALLSGCNDYLTKPVNLHWLSKKITEWGCMQALIDFDSWKQGESRMTDSVLVKSPQKPIAPSNPHSFKQATSMTPTHSPVRKNSNLSPTQIEL", "length": 712, "molWeight": 78529, "crc64": "33B2DBB4FCF2528A", "md5": "4DCD3B7A753424255D8140202721EF04"}}
{"primaryAccession": "Q07508", "text": "This is Protein LUC7 protein, from Baker's yeast, contains 261 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q07508", "organism_name": "Baker's yeast", "protein_name": "Protein LUC7", "length": 261, "firstPublicDate": "2006-10-31", "FUNCTION": "Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA, Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Luc7 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSTMSTPAAEQRKLVEQLMGRDFSFRHNRYSHQKRDLGLHDPKICKSYLVGECPYDLFQGTKQSLGKCPQMHLTKHKIQYEREVKQGKTFPEFEREYLAILSRFVNECNGQISVALQNLKHTAEERMKIQQVTEELDVLDVRIGLMGQEIDSLIRADEVSMGMLQSVKLQELISKRKEVAKRVRNITENVGQSAQQKLQVCEVCGAYLSRLDTDRRLADHFLGKIHLGYVKMREDYDRLMKNNRTTNASKTATTLPGRRFV", "length": 261, "molWeight": 30195, "crc64": "F6CFA1947C1C86B1", "md5": "7C933646F17E7894B852508C4068565F"}}
{"primaryAccession": "Q07845", "text": "This is Polynucleotide 5'-hydroxyl-kinase GRC3 protein, from Baker's yeast, contains 632 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q07845", "organism_name": "Baker's yeast", "protein_name": "Polynucleotide 5'-hydroxyl-kinase GRC3", "length": 632, "firstPublicDate": "2005-10-25", "FUNCTION": "Polynucleotide 5'-kinase involved in rRNA processing, Required for the efficient termination by RNA polymerase I and the processing of the IST2 pre-rRNA internal transcribed spacer localized between the 5,8S and 25S rRNAs, May act by maintaining the phosphorylated status of the downstream RNT1 cleavage product, which in turn allows the torpedo activity of RAT1 to efficiently terminate Pol I transcription, In vitro, displays polynucleotide kinase activity on both single- and double-stranded RNA and on single-stranded DNA alone, but not double-stranded DNA alone", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Clp1 family, NOL9/GRC3 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVIDSKQDLPQYTKDSGSESDSDSSNNFIVESPSIPSSKSATVVLNSEEYEDDEGDDLNGLDAELIDNITYEGDEDETMFVGLKEKQKLHLSGVFRLQVVKGGIVYNNVHYNASREILTFWHPLSQSIPTIDFSHFAGWQDTFFMPRNNRFKIRDEEFKSFPCVLRVFNSNHTGLLEAGHLYRDVNYLWKPKEPYFPLNERTTYHLLHESDRIQSLSVPGYWSTPLEKLYLSHKNAAYDTRIMVIGGKNSGKSTFLRLLLEKFTQDIRDSTTSQEELVYLDLDPGQPEYSLPDSISLNKILSSPISLGQHLCQGSNFQTLLQFYAGSSSPQDEPTSYLNCADKLIDHLEEQAFFGTSLLNLPGWIKGFGMQILNHIIRKYKPTHLLFLETANSKRHLDELTIPQSFSTSLRDAYAPEVVRVPAHSLNHTLSSRFHASQLRTFKILALFHKITQFDYDFAPLLKSAPLQISYGKGKSGIKGIQFPMEFQDLNPQDIKSALEGTVIGIYTYSGEDSLEVKSLNTFPILQSCTSSSKNFITLGLIHSIDTSQQIMNIYVPPCHTQILDKQPEDAQWIIVRNKTETPFCDFLPSPRTITWDDNIQIPFATFERRKKLEHVWKVRKNVMRRGQFMKR", "length": 632, "molWeight": 72258, "crc64": "1F45D9E16E7EA1E8", "md5": "9753772DFEBD1352B664F65850695DC1"}}
{"primaryAccession": "Q07913", "text": "This is Non-structural maintenance of chromosomes element 1 protein, from Baker's yeast, contains 336 amino acids, has 1 RING-type; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [268, 327], "description": "RING-type; atypical", "keyword_description": "Zinc finger", "textural_description": "RING-type; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q07913", "organism_name": "Baker's yeast", "protein_name": "Non-structural maintenance of chromosomes element 1", "length": 336, "firstPublicDate": "2005-10-25", "FUNCTION": "Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage, Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the NSE1 family", "domain_description": {"RING-type; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEVHEEQVSAPVTGDATAKYLLQYILSARGICHENALILALMRLETDASTLNTEWSIQQWVDKLNDYINAINVKLNLLGYKIIRINHGIGRNAVTLKAKQNFESFEDNTAIRAHNNDYAVLQSIVLPESNRFFVYVNLASTEETKLATRFNQNEIEFMKWAIEQFMISGETIVEGPALETSIIVKEVNRILVAATGDSNLAKWRKFSTFTVGSTNLFQFQELTATDIEDLLLRLCELKWFYRTQEGKFGIDLRCIAELEEYLTSMYNLNTCQNCHKLAIQGVRCGNESCREENEETGENSLSQIWHVDCFKHYITHVSKNCDRCGSSLITEGVYVI", "length": 336, "molWeight": 38335, "crc64": "43237EFB55B44042", "md5": "EB7736B9C8B1BA61920D341E9E5B9CF5"}}
{"primaryAccession": "Q08179", "text": "This is Mitochondrial distribution and morphology protein 38 protein, from Baker's yeast, contains 573 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08179", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial distribution and morphology protein 38", "length": 573, "firstPublicDate": "2005-04-12", "FUNCTION": "Involved in mitochondrial potassium homeostasis through the mitochondrial K(+)/H(+) exchange regulation (PubMed:11907266, PubMed:15138253), With MBA1, plays a role in ribosomal translation and protein insertion into the inner membrane (PubMed:20427570)", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLNFASRASCVTRRQASLYFVKNQGPRLIASTIPSCHWPLRAQGVQPNYPLSLRFYSTDKSKSVTKPVAPTSTDAPAKPKETLMVKVKHALKHYANGTKLLGYEIKVSTKLLIKFAQGYELSRRERNQLRRTMGDVFRLIPFSAFLIIPFAELFLPFALKLFPNLLPSTYESGKDKQAKRNKLIEIRKKTSEFLHETLEESNLITYNTIENAEKKQKFLNFFRKLYSAKEGKIMTFQHDEISAIAQMFKNDSVLDNLSRPQLAAMSKFMSLRPFGNDNMLRYQIRSKLKDIMNDDKTIDYEGVESLSQEELYQACVSRGMKAYGVSKEDLVDNLKVWLELRLRQKIPSVLMVLSSTFTFGGLPKENYSKAFSPLAEKKETKSKYDDLLDLYYDGILQVLSSIPDPVYNVAKLDVSESKSSAAETEAEKQVAEKKIKTEEKPEETAIPKEEATAKESVIATTASAVTPKLVVVNEKAETAKTEEISQEKENAEPTDSAEATEAEEKKTSDDNEFKLNVLKEQEELIKKEEEEAKQRASREHVPDDINLDEEEEAKSVPPIPADQAAKTFVIKKD", "length": 573, "molWeight": 65005, "crc64": "5F34453EC009F311", "md5": "1F265C2AD4A176055A79614D36A41F9B"}}
{"primaryAccession": "Q08230", "text": "This is Succinate dehydrogenase assembly factor 2, mitochondrial protein, from Baker's yeast, contains 162 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08230", "organism_name": "Baker's yeast", "protein_name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "length": 162, "firstPublicDate": "2005-08-16", "FUNCTION": "Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol, Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDH1 of the SDH catalytic dimer, It is unclear whether it participates in the chemistry of FAD attachment (enzymatic function) or acts as a chaperone that maintains SDH1 in a conformation that is susceptible to autocatalytic FAD attachment (PubMed:19628817), Does not bind FAD or FADH(2) in vitro (PubMed:23062074), Involved in sporulation (PubMed:12432101), Required for the full activation of the early meiotic inducer IME1 (PubMed:12586695)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the SDHAF2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MHNMFPALTKTLSLQGYKIINSQTGSAAWSCGRRWFSSDKDDHDDVVTRIKIAPIKRTNEPLDKKRARLIYQSRKRGILETDLLLSGFAAKYLKKMNEEELEEYDSLLNELDWDIYYWATKNFKTSPLPDKWANSKLLKQLQEFSENKEKEILSMPDLSKYQ", "length": 162, "molWeight": 19042, "crc64": "8CDF8E943D46A12D", "md5": "DB4E6AC365A7A04E2C92F5021EA51151"}}
{"primaryAccession": "Q08235", "text": "This is Ribosome biogenesis protein BRX1 protein, from Baker's yeast, contains 291 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08235", "organism_name": "Baker's yeast", "protein_name": "Ribosome biogenesis protein BRX1", "length": 291, "firstPublicDate": "2003-05-09", "FUNCTION": "Required for biogenesis of the 60S ribosomal subunit", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the BRX1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSIYKALAGKSKDNKSEKKQGNVKQFMNKQRTLLISSRGVNYRHRHLIQDLSGLLPHSRKEPKLDTKKDLQQLNEIAELYNCNNVLFFEARKHQDLYLWLSKPPNGPTIKFYIQNLHTMDELNFTGNCLKGSRPVLSFDQRFESSPHYQLIKELLVHNFGVPPNARKSKPFIDHVMSFSIVDDKIWVRTYEISHSTKNKEEYEDGEEDISLVEIGPRFVMTVILILEGSFGGPKIYENKQYVSPNVVRAQIKQQAAEEAKSRAEAAVERKIKRRENVLAADPLSNDALFK", "length": 291, "molWeight": 33531, "crc64": "31466853EF0E7301", "md5": "730877B9E77B452A91E0DC54CB5AA72C"}}
{"primaryAccession": "Q08278", "text": "This is Mediator of RNA polymerase II transcription subunit 7 protein, from Baker's yeast, contains 222 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08278", "organism_name": "Baker's yeast", "protein_name": "Mediator of RNA polymerase II transcription subunit 7", "length": 222, "firstPublicDate": "2003-02-28", "FUNCTION": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes, Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors, The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II, The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Mediator complex subunit 7 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSNDPGNEVSSLYPPPPPYVKFFTQSNLEKLPKYKEKKAASAKQTAPNNSNGGSEEEITCALDYLIPPPMPKNQQYRAFGSIWQVKDQLPDLESMGLTQLYKKSTENESTNYQYKIQELRKLLKSLLLNYLELIGVLSINPDMYERKVENIRTILVNIHHLLNEYRPHQSRESLIMLLEEQLEYKRGEIREIEQVCKQVHDKLTSIQDTLRTGSQSPPSSSQ", "length": 222, "molWeight": 25585, "crc64": "A88301E4EF3223C9", "md5": "79AE56D58C9A640055497DB9E37F20C6"}}
{"primaryAccession": "Q08288", "text": "This is Cell growth-regulating nucleolar protein protein, from Mouse, contains 388 amino acids, has 2 C2HC LYAR-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [1, 26], "description": "C2HC LYAR-type", "keyword_description": "Zinc finger", "textural_description": "C2HC LYAR-type Zinc finger"}, {"location": [28, 52], "description": "C2HC LYAR-type", "keyword_description": "Zinc finger", "textural_description": "C2HC LYAR-type Zinc finger"}], "meta_data": {"primaryAccession": "Q08288", "organism_name": "Mouse", "protein_name": "Cell growth-regulating nucleolar protein", "length": 388, "firstPublicDate": "1997-11-01", "FUNCTION": "Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (By similarity), Also acts at the level of transcription regulation, Along with PRMT5, binds embryonic globin promoter (By similarity), Represses the expression of embryonic globin Hbb-y gene (PubMed:25092918), In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and that encoding the small nucleolar RNA SNORD41 (By similarity), Preferentially binds to a DNA motif containing 5'-GGTTAT-3' (By similarity), Negatively regulates the antiviral innate immune response by targeting IRF3 and impairing its DNA-binding activity (By similarity), In addition, inhibits NF-kappa-B-mediated expression of pro-inflammatory cytokines (By similarity), Stimulates phagocytosis of photoreceptor outer segments by retinal pigment epithelial cells (PubMed:25735755), Prevents NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal (PubMed:19489080)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2HC LYAR-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVFFTCNACGESVKKIQVEKHVSNCRNCECLSCIDCGKDFWGDDYKSHVKCISEGQKYGGKGYEAKTHKGDAKQQAWIQKINELIKKPNVSPKVRELLQQISAFDNVPRKKAKFQNWMKNSLKVHSDSVLEQVWDIFSEASSSEQDQQQPPSHTAKPHAEMPITKVPSAKTNGTTEEQTEAKKNKRERKEERQKNRKKEKKELKLENHQENLRGQKPKKRKKNQEAGHEAAGEEAAEASGPPEKKKAQGGQASEEGADRNGGPGEDAAEGQTKTAAGKRKRPKHSGAESGYKKKKMKLPEQPEEGEAKDHEAPSKGKFNWKGTIKAVLKQAPDNEISVKKLKKKVIAQYHAVMNDHHTSEEELLAIFNRKISRNPTFKVLKDRVKLLK", "length": 388, "molWeight": 43736, "crc64": "D39A0CDC2257BE8C", "md5": "F8649EBF315B2BC5ED72DDBAEAEA2D70"}}
{"primaryAccession": "Q08412", "text": "This is Ubiquitin-binding protein CUE5 protein, from Baker's yeast, contains 411 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08412", "organism_name": "Baker's yeast", "protein_name": "Ubiquitin-binding protein CUE5", "length": 411, "firstPublicDate": "2007-01-09", "FUNCTION": "Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 adapter and thus mediating autophagic clearance of ubiquitin conjugates under starvation conditions, The CUE5-dependent selective autophagy pathway plays an important role in clearance of cytotoxic protein aggregates, Not required for cytoplasmic to vacuole pathway (cvt), mitophagy, pexophagy, or ribophagy", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEEKEGIKDSSLLEKSNVPESINEDISKTTDVDLNSDGKKDNDTSAKDGTPKVEEKVNKSSGIDEDEVVTPAEDAKEEEEEHPPLPARRKSEEEPSKENPILQELKDAFPNLEEKYIKAVIIASQGVLSPAFNALLFLSDPESGKDIELPTQPVRKNPEAPARRRQTQLEQDELLARQLDEQFNSSHSRRRNRDRATRSMHEQRRRRHNPNEREQHHEDSEEEDSWSQFVEKDLPELTDRAGRSLQDTANKVSNWISDAYRRNFASGNEQNDNQHGHQDQQEWEPEIVDLSQGGKNSRPQQPERRRFNSFGVQVGDDSLESHGITLHNEDGFEDDEDVPPQLPTRTKSGESTGKVVAETTYIDTPDTETKKKWQPLPPEPLDTTPTKVNAVSRNKKNPDEDEFLINSDDEM", "length": 411, "molWeight": 46870, "crc64": "0D455F9AD637AC8D", "md5": "A4101E46D0FCA93841475990910902E7"}}
{"primaryAccession": "Q08465", "text": "This is Protein YNG1 protein, from Baker's yeast, contains 219 amino acids, has 1 PHD-type; degenerate Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [155, 204], "description": "PHD-type; degenerate", "keyword_description": "Zinc finger", "textural_description": "PHD-type; degenerate Zinc finger"}], "meta_data": {"primaryAccession": "Q08465", "organism_name": "Baker's yeast", "protein_name": "Protein YNG1", "length": 219, "firstPublicDate": "2006-06-13", "FUNCTION": "Histone-binding component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3, Recruitment of NuA3 to nucleosomes requires methylated histone H3, In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation, YNG1 is required for the HAT activity of NuA3 but not for its integrity, Mediates the interaction of SAS3 with nucleosomes", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ING family", "domain_description": {"PHD-type; degenerate Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEHLANENSDSDIRYSFLSTLDHLPCELIRSLRLMQTIDLFKNEEDEPGMERACRDLLLVATYINDLVDDQIHFLKQHKKELEIQKSVTKNFNSSLENIKSKLTLEEPGAYKEPKLLLKINLKKAKSRERKESITSPTIGINQGDVTEGNNNQEEVYCFCRNVSYGPMVACDNPACPFEWFHYGCVGLKQAPKGKWYCSKDCKEIANQRSKSKRQKRRK", "length": 219, "molWeight": 25350, "crc64": "5232A71839E2FDA4", "md5": "C524801913A23AFF61FCE9E3305F73B1"}}
{"primaryAccession": "Q08605", "text": "This is Transcription factor GAGA protein, from Fruit fly, contains 581 amino acids, has 1 C2H2-type; degenerate Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [343, 366], "description": "C2H2-type; degenerate", "keyword_description": "Zinc finger", "textural_description": "C2H2-type; degenerate Zinc finger"}], "meta_data": {"primaryAccession": "Q08605", "organism_name": "Fruit fly", "protein_name": "Transcription factor GAGA", "length": 581, "firstPublicDate": "1995-02-01", "FUNCTION": "Transcriptional activator that functions by regulating chromatin structure, Overcomes the repressive effects of chromatin by promoting the open chromatin conformation in promoter gene regions, thereby allowing access to other transcription factors, Binds to DNA Polycomb response elements (PREs) at the bithorax complex and to the proximal region of the engrailed promoter, and positively regulates transcription of many genes including homeotic ones, Binds to the DNA sequence (GA)n, with optimal binding to the pentamer 5'-GAGAG-3', Binds DNA as an oligomer, May also act as a transcriptional repressor, maintaining the repressed state of genes including lolal, and down-regulating its own transcription, Required for dosage compensation in males and may be involved in oogenesis, Also has a role in nuclear division", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type; degenerate Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSLPMNSLYSLTWGDYGTSLVSAIQLLRCHGDLVDCTLAAGGRSFPAHKIVLCAASPFLLDLLKNTPCKHPVVMLAGVNANDLEALLEFVYRGEVSVDHAQLPSLLQAAQCLNIQGLAPQTVTKDDYTTHSIQLQHMIPQHHDQDQLIATIATAPQQTVHAQVVEDIHHQGQILQATTQTNAAGQQQTIVTTDAAKHDQAVIQAFLPARKRKPRVKKMSPTAPKISKVEGMDTIMGTPTSSHGSGSVQQVLGENGAEGQLLSSTPIIKSEGQKVETIVTMDPNNMIPVTSANAATGEITPAQGATGSSGGNTSGVLSTPKAKRAKHPPGTEKPRSRSQSEQPATCPICYAVIRQSRNLRRHLELRHFAKPGVKKEKKTTSGKKSSSGSSGSGSGALSSSGSVPQVQTVQSLHTLQGVQVKKDPDAQQQQQQQQQQQQQQQQAMTVSGATGGQVQQQVQQVQQQVQQQQQQQQQQQQQLQHHQIIDSSGNITTATTSAQAAAAAQQQAAGQQQQLVAQSDGSESGAPLSIAQVQTLQGHQIIGNLNQVNMTDFQQQQPQQQQQQQQQQQQQQQQQQQTQQTL", "length": 581, "molWeight": 62489, "crc64": "04826A1B630E3320", "md5": "CE132A4ADE79E56E9867A5C2CE171FF7"}}
{"primaryAccession": "Q08881", "text": "This is Tyrosine-protein kinase ITK/TSK protein, from Human, contains 620 amino acids, has 1 Btk-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [113, 149], "description": "Btk-type", "keyword_description": "Zinc finger", "textural_description": "Btk-type Zinc finger"}], "meta_data": {"primaryAccession": "Q08881", "organism_name": "Human", "protein_name": "Tyrosine-protein kinase ITK/TSK", "length": 620, "firstPublicDate": "1994-10-01", "FUNCTION": "Tyrosine kinase that plays an essential role in regulation of the adaptive immune response, Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells, When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation lead to the recruitment of ITK to the cell membrane, in the vicinity of the stimulated TCR receptor, where it is phosphorylated by LCK, Phosphorylation leads to ITK autophosphorylation and full activation, Once activated, phosphorylates PLCG1, leading to the activation of this lipase and subsequent cleavage of its substrates, In turn, the endoplasmic reticulum releases calcium in the cytoplasm and the nuclear activator of activated T-cells (NFAT) translocates into the nucleus to perform its transcriptional duty, Phosphorylates 2 essential adapter proteins: the linker for activation of T-cells/LAT protein and LCP2, Then, a large number of signaling molecules such as VAV1 are recruited and ultimately lead to lymphokine production, T-cell proliferation and differentiation (PubMed:12186560, PubMed:12682224, PubMed:21725281), Required for TCR-mediated calcium response in gamma-delta T-cells, may also be involved in the modulation of the transcriptomic signature in the Vgamma2-positive subset of immature gamma-delta T-cells (By similarity), Phosphorylates TBX21 at 'Tyr-530' and mediates its interaction with GATA3 (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, Tyr protein kinase family, TEC subfamily", "domain_description": {"Btk-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRIKCVEIVKSDISIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETRNNNSLVPKYHPNFWMDGKWRCCSQLEKLATGCAQYDPTKNASKKPLPPTPEDNRRPLWEPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTAGTYTVSVFTKAVVSENNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPVTAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESGL", "length": 620, "molWeight": 71831, "crc64": "DAE396BD2309319D", "md5": "BC739105238EB6E59A00EF883D06430B"}}
{"primaryAccession": "Q08960", "text": "This is S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase protein, from Baker's yeast, contains 810 amino acids, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08960", "organism_name": "Baker's yeast", "protein_name": "S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase", "length": 810, "firstPublicDate": "1997-11-01", "FUNCTION": "Component of the wybutosine biosynthesis pathway, Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA, Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the TYW1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDGFRVAGALVVGALTAAYLYFGGRFSIALVIIVGYGIYCNEASGGSQDSQEKLDLNKQQKKPCCSDKKIADGGKKTGGCCSDKKNGGGKGGGCCSSKGGKKGGCCSSKGGKKGGCCSSKKNIGDNENTATEVEKAVNYPVTVDFTEVFRKPTKKRSSTPKVFSKNSSSNSRVGKKLSVSKKIGPDGLIKSALTISNETLLSSQIYVLYSSLQGAASKAAKSVYDKLKELDELTNEPKLLNLDDLSDFDDYFINVPVENALYVLVLPSYDIDCPLDYFLQTLEENANDFRVDSFPLRKLVGYTVLGLGDSESWPEKFCYQAKRADHWISRLGGRRIFPLGKVCMKTGGSAKIDEWTSLLAETLKDDEPIIYEYDENADSEEDEEEGNGSDELGDVEDIGGKGSNGKFSGADEIKQMVAKDSPTYKNLTKQGYKVIGSHSGVKICRWTKNELRGKGSCYKKSLFNIASSRCMELTPSLACSSKCVFCWRHGTNPVSKNWRWEVDEPEYILENALKGHYSMIKQMRGVPGVIAERFAKAFEVRHCALSLVGEPILYPHINKFIQLLHQKGITSFLVCNAQHPEALRNIVKVTQLYVSIDAPTKTELKKVDRPLYKDFWERMVECLEILKTVQNHQRTVFRLTLVKGFNMGDVSAYADLVQRGLPGFIEVKGATFSGSSDGNGNPLTMQNIPFYEECVKFVKAFTTELQRRGLHYDLAAEHAHSNCLLIADTKFKINGEWHTHIDFDKFFVLLNSGKDFTYMDYLEKTPEWALFGNGGFAPGNTRVYRKDKKKQNKENQETTTRETPLPPIPA", "length": 810, "molWeight": 89805, "crc64": "C6A18C949B6E5F8B", "md5": "35A3D647DF09054D91163B66813CB206"}}
{"primaryAccession": "Q08968", "text": "This is Protein adenylyltransferase SelO, mitochondrial protein, from Baker's yeast, contains 688 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08968", "organism_name": "Baker's yeast", "protein_name": "Protein adenylyltransferase SelO, mitochondrial", "length": 688, "firstPublicDate": "1998-07-15", "FUNCTION": "Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Tyr residues of target mitochondrial proteins (AMPylation) (PubMed:30270044), Involved in redox homeostasis by regulating the cellular response to oxidative stress (PubMed:30270044), Regulates protein S-glutathionylation levels possibly by AMPylation of deglutathionylation enzymes such as glutaredoxins (PubMed:30270044)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the SELO family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGEKRTIIKALKNSAASHFIKKLTADTSLSSIQEAINVVQQYNATDPVRLKLFHTPRMVSQGAHFAFCLPTKKPHYKPLLLSQNALDEFNLVQDQDLEKILSGEKVYYSDSIFPYSTVYSGFQFGSFAAQLGDGRVVNLFDLKDKCSGQWQTFQLKGAGMTPFSRFADGKAVLRSSIREFIMSEALHSIGIPSTRAMQLTLLPGTKAQRRNQEPCAVVCRFAPSWIRLGNFNLFRWRHDLKGLIQLSDYCIEELFAGGTQFEGKPDFNIFKRDFFPDTETKIDEQVEKDETEVSTMTGDNISTLSKYDEFFRHVVSLNANTVAHWQAYGFANGVLNTDNTSIMGLTIDYGPFAFLDKFEPSFTPNHDDTAKRYSFANQPSIIWWNLQQFAKDLACLLGPEARDLELLLKGELNSVDDALEKTMIERVQKLVELSANEYKYVFTTRYAQIMSQRLGVDLDLEKCMSSTNLKDIEHAAEKAKEFCDVIVEPLLDILQATKVDYNNFFIHLQNYKGPFFIKDKSDTATLFGAFDEEYLGMFFNSKQLQQMAETEEAFAAGEKVFDANGELRLLNEKLQEIRNWTQDYLTLVPPTETAARASLAKKANPLFVPRSWVLEEVVDDLMYSQRDGLQDPSSELDTSALKKLYLMSVNPYDRTKWDVTLRPELETKWADLSHQDDAKFMMQASCSS", "length": 688, "molWeight": 78313, "crc64": "7C56CD503ED24B1E", "md5": "431BFF1D038DD0C3A4D874C2138BEFBA"}}
{"primaryAccession": "Q09175", "text": "This is Dibasic-processing endoprotease protein, from Fission yeast, contains 709 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09175", "organism_name": "Fission yeast", "protein_name": "Dibasic-processing endoprotease", "length": 709, "firstPublicDate": "1995-11-01", "FUNCTION": "Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins, Essential for cell viability, Cleaves substrate on the C-terminal side of dibasic residues", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the peptidase S8 family, Furin subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MHPALLCGPILAIFLQFLVSSCSPLENDDLFLVQVEPEVDPVVAAEAIGAKYVRPLLNLKYHHLIKLHKGSDDSVQSSIRKRGIDAGILELERQTPRWRYKRDASESDELLNEFSNHFGISDPLFYGQWHIFNSNNPGHDLNLREVWDAGYFGENVTVAFVDDGIDFKHPDLQAAYTSLGSWDFNDNIADPLPKLSDDQHGTRCAGEVAAAWNDVCGVGIAPRAKVAGLRILSAPITDAVESEALNYGFQTNHIYSCSWGPADDGRAMDAPNTATRRALMNGVLNGRNGLGSIFVFASGNGGHYHDNCNFDGYTNSIFSATIGAVDAEHKIPFYSEVCAAQLVSAYSSGSHLSILTTNPEGTCTRSHGGTSAAAPLASAVYALALSIRPDLSWRDIQHITVYSASPFDSPSQNAEWQKTPAGFQFSHHFGFGKLDASKFVEVAKDWQVVNPQTWLIAPEINVNKSFGSVNNETITEMVSEFTVTKDMIEKSNFKRLEHVTVRVCIPFNRRGALEILLESPSGIRSILASERPYDENSKGFLDWTFMTVQHWAEPPEGVWKLLVNDRSGGKHEGTFENWQLALWGESENPSNTAPLPYDTLELPKEMVLGIYSEPNSDLTNSSTLLSPTSTSFTSYTVSATATPTSTSHIPIPTVLPPTQPVLEPSYREIVAFITFFLLFAFIFVAVIWTWISAFWKAKAPPPLSQQEIA", "length": 709, "molWeight": 78127, "crc64": "414FE9B89CBE0840", "md5": "4B333D28C6E30C78C1BC30223A11231C"}}
{"primaryAccession": "Q09685", "text": "This is Pre-mRNA-splicing factor dre4 protein, from Fission yeast, contains 411 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09685", "organism_name": "Fission yeast", "protein_name": "Pre-mRNA-splicing factor dre4", "length": 411, "firstPublicDate": "1995-11-01", "FUNCTION": "Component of the spliceosome involved in mRNA processing", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSQPLPPGWTEHKAPSGIPYYWNAELKKSTYQRPSFIEKNHSSSVTASQASLAFNTSEKLFVNENAEERKNSRDLRKQLPDRPKFKKRIPNNDSWVVVFTKKNRYFFHNLKSHESYWEPPLEISKDLKILRLPIRKQISKDSSQSQNVDSGKTNHEEIHESRHLQTEIEEPSGLEESSEESVLYSEEFYEKSDEEEDEEKSHSAEELEFGEEDIMYQLQQLDDETVSYDIQEQATNLSTDDARRVFTELLKDKNIGAYQPWELVYPKLLDDDRFYVLDSGERRKEVFEEYCKSVVSTKKITRRKNTLSDFWTLLHSLPSTLLWPQFKRKYRKSSTLQIPGYSERDFEKLFREFQILRKQPMQDKLLNFKKLCKSKTVDPKNPDEFTESILNDTRYAVLTREELDSLACSSN", "length": 411, "molWeight": 48519, "crc64": "7A89C5F7397B8AAF", "md5": "539306D81511FE12E89885F6130A9EF7"}}
{"primaryAccession": "Q09808", "text": "This is SMN complex subunit smn1 protein, from Fission yeast, contains 152 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09808", "organism_name": "Fission yeast", "protein_name": "SMN complex subunit smn1", "length": 152, "firstPublicDate": "1995-11-01", "FUNCTION": "The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs (PubMed:20400941, PubMed:33754639, PubMed:10749974), Most spliceosomal snRNPs contain a common set of Sm proteins smb1, smd1, smd2, smd3, sme1, smf1 and smg1 that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core) (By similarity), In the cytosol, the Sm proteins smd1, smd2, sme1, smf1 and smg1 (5Sm) are trapped in an inactive 6S pICln-Sm complex by the chaperone saf5 that controls the assembly of the core snRNP (By similarity), To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from saf5 forming an intermediate (By similarity), Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of smd3 and smb1 to complete assembly of the core snRNP (By similarity), Within the SMN complex, smn1 acts as a structural backbone and together with yip11/gem2 it gathers the Sm complex subunits (PubMed:33754639)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SMN family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDQSQKEVWDDSELRNAFETALHEFKKYHSIEAKGGVSDPDSRLDGEKLISAARTEESISKLEEGEQMINQQTETTLEGDTHIQQFADNKGLSDEKPETRAAETHQEFMEVPPPIRGLTYDETYKKLIMSWYYAGYYTGLAEGLAKSEQRKD", "length": 152, "molWeight": 17385, "crc64": "CC64455AFC2CFEE6", "md5": "09E39F308E2C62E48D65B21FF3D75EC1"}}
{"primaryAccession": "Q0E7J7", "text": "This is Protein stn1 protein, from Fission yeast, contains 325 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0E7J7", "organism_name": "Fission yeast", "protein_name": "Protein stn1", "length": 325, "firstPublicDate": "2007-12-04", "FUNCTION": "Required for telomere maintenance", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLENENQLTHQFPTLSRWNPMFISDVHKISFHPHLQRYIGFWMGFPIRWIQIVGYIAAIDIYEGKHVLTVDDCSGMVLRVVFIIQDDFSMSKRAISMSPGNVVCVFGKINSFRSEVELIAQSFEELRDPNDEWKAWQKRMRYKKNLTKISKNHHSIIRTPKKSYFPKDHAKELLKCIRQMCKLNVQAGFTIEELIIYLKAKELHLPLVHIFNVENEIVENCDGNHILALNFSLQTLLQHGRIVRKSNSVYMLVTSKDIIRFVIPLMASGLLEAHKVQSIVRDSNPMFITLPLSAIAKHICQFLLRTKGKWRQAKKYTWVRDNQFV", "length": 325, "molWeight": 37995, "crc64": "9664D09FC59ADE1B", "md5": "EF3450B29A8FD14741330C1FCEF5428C"}}
{"primaryAccession": "Q0MW30", "text": "This is E3 ubiquitin-protein ligase NEURL1B protein, from Mouse, contains 546 amino acids, has 1 RING-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [494, 534], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q0MW30", "organism_name": "Mouse", "protein_name": "E3 ubiquitin-protein ligase NEURL1B", "length": 546, "firstPublicDate": "2008-09-02", "FUNCTION": "E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGNTVHRTLPDSSPPARLLATRPCYGPGPERRAVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESTFADTLTPLRLGQARLSACPPPGSHDAANFDNNELENNQVVAKLGHLALGRPDAAVPCVARERPRPASSPALLDAELRFHATRGPDVSLSADRRLACAPRPDGGRTLVFSERPLRPGESLCVEVGRPGLAAPAAVAFGITSCDPGALRPSELPADPAALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLAVNGRPRGRLLCVDTSQALWAFFAVRGGVAGQLRLLGTLQSSSETMTPSGSFSGSQDDSDSDMTFGVNQSSSASESSLVTAPSSPLSPPVSPAFSAPEPTGSRNGECTVCFDSEVDTVIYTCGHMCLCHGCGLRLRRQARACCPICRRPIKDVIKIYRP", "length": 546, "molWeight": 58527, "crc64": "7201090850E88DD1", "md5": "4BC4944A19C71DA36977B941D437ABAE"}}
{"primaryAccession": "Q0V8E7", "text": "This is Receptor for retinol uptake STRA6 protein, from Bovine, contains 668 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0V8E7", "organism_name": "Bovine", "protein_name": "Receptor for retinol uptake STRA6", "length": 668, "firstPublicDate": "2007-11-13", "FUNCTION": "Functions as retinol transporter, Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1 (PubMed:17255476, PubMed:18419130), Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A, Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin, Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid, STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency, Does not transport retinoic acid (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSTQAAGNQTSSGATDSEDSYDSWYIDEPQGGQELQPEGLVPSCQPNVPPSLYHTCLAVLSILVLFLLAMLVRRRQLWPRCGHGRPGLPSPVDFLTGDRPRTVPAAVFMVLFSSLCLLLPTEDPLPFLSLASPPGRDGEAETSRGPWKILALLYYPALYYPLAACATVRHGAAHLLGSLLSWAHLGVQVWQRAECPESPKIYKYYSLLASLPLLLGLGFLSLWYPVQLVRSFGHGAATGSKGLQSSYSEEYLRTLLCQKKLKSSSHTCKRGFASQAWMYFRHSVYIPQRGFRLPLKLVLSVTLTGTAIYQVALLLLVGVVPTIQKVRAGITTDVSYLLAGFGIVLSEDRQEVVELVKHHLWALEVCYISALVLSCLLTFLMLVHSLVTHRTNLRALHRGGALDIGPLTQSPRPSRQAIFCWMSFTAYQTAFTCLGLLVQQILFFLGTLTLAFLVFMPMLHGRNLLLLHYLKSSWPFWLTLALAVTLQNAAAHWAFLDTHHGRPGLTNRRALYAATFLLFPVNVLVGTMVAAWRVLLSALYNAVHLGRMDLSLLPLRAATLDPGYHTYCNFLRMEASQSHPAATAFCALLLRTQRPKPRATPQDGLRLGEEEEGIQLLQTKDLVAKGAGPRARQGRARWGLAYTLLHNPALQAFRKTALPGARPNGAQP", "length": 668, "molWeight": 73762, "crc64": "72084B0D39DC8B6F", "md5": "5EE937181BC178D69C5337C629C8DA08"}}
{"primaryAccession": "Q0VAK6", "text": "This is Leiomodin-3 protein, from Human, contains 560 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0VAK6", "organism_name": "Human", "protein_name": "Leiomodin-3", "length": 560, "firstPublicDate": "2006-11-28", "FUNCTION": "Essential for the organization of sarcomeric actin thin filaments in skeletal muscle (PubMed:25250574), Increases the rate of actin polymerization (PubMed:25250574)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the tropomodulin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSEHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQQQLKEQKKLIAMLENGLGLPPGMWELLGGPKPDSRMQEFFQPPPPRPPNPQNVPFSQRSEMMKKPSQAPKYRTDPDSFRVVKLKRIQRKSRMPEAREPPEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSSVAYLKPVQLPKELA", "length": 560, "molWeight": 64914, "crc64": "762412021EDEDE08", "md5": "4937A78269B881ED475F337B5D6289EE"}}
{"primaryAccession": "Q0WNX9", "text": "This is Cyclin-dependent kinase inhibitor 6 protein, from Mouse-ear cress, contains 196 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0WNX9", "organism_name": "Mouse-ear cress", "protein_name": "Cyclin-dependent kinase inhibitor 6", "length": 196, "firstPublicDate": "2007-07-10", "FUNCTION": "Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity, Regulates cell division which is crucial for plant growth, development and morphogenesis, May inhibit CDK kinases specifically involved in the G1/S phase transition", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CDI family, ICK/KRP subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSERKRELAEEASSTSFSPLKKTKLNDSSDSSPDSHDVIVFAVSSSSVASSAALASDECSVTIGGEESDQSSSISSGCFTSESKEIAKNSSSFGVDLEDHQIETETETSTFITSNFRKETSPVSEGLGETTTEMESSSATKRKQPGVRKTPTAAEIEDLFSELESQDDKKKQFIEKYNFDIVNDEPLEGRYKWDRL", "length": 196, "molWeight": 21454, "crc64": "AC543304CE6B92C4", "md5": "1FCCDD77214DAF0E7D6348FE454F040D"}}
{"primaryAccession": "Q0WP36", "text": "This is Molybdate transporter 2 protein, from Mouse-ear cress, contains 464 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0WP36", "organism_name": "Mouse-ear cress", "protein_name": "Molybdate transporter 2", "length": 464, "firstPublicDate": "2012-05-16", "FUNCTION": "Molybdate transporter required for vacuolar molybdate export during senescence", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the SLC26A/SulP transporter (TC 2,A,53) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "METTTTPLLPGDRSRCGWLRRRLRLKNPLSSELSGAVGDLGTFIPIVLTLTLVSNLDLSTTLIFTGFYNIATGLLFDIPMPVQPMKSIAAVAVSESPHLTPSQIAAAGASTAATLLLLGATGAMSFLYNIIPLPVVRGVQLSQGLQFAFTAIKYVRFNYDTATLKPSSSPRIWLGLDGLILALAALLFIILSTGSGNDREAEDGDLAETSSNESQSRRRRLRLLSSIPSALIVFALGLVLCFIRDPSIFKDLKFGPSKFHILRISWDDWKIGFLRAAIPQIPLSVLNSVIAVCKLSNDLFDKELSATTVSISVGVMNLIGCWFGAMPVCHGAGGLAGQYRFGARSGLSVIFLGIGKLIVGLVFGNSFVRILSQFPIGILGVLLLFAGIELAMASKDMNSKEDSFIMLVCAAVSMTGSSAALGFGCGVVLYLLLKLRTLDCSSVTLFSRSSDESQVDSEAAPRDV", "length": 464, "molWeight": 49551, "crc64": "7C8AC36E8580C312", "md5": "4738C10FDC0000BB93C6FA4F0F29D0FB"}}
{"primaryAccession": "Q0WQE7", "text": "This is AUGMIN subunit 3 protein, from Mouse-ear cress, contains 617 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0WQE7", "organism_name": "Mouse-ear cress", "protein_name": "AUGMIN subunit 3", "length": 617, "firstPublicDate": "2015-10-14", "FUNCTION": "Involved in microtubules reorganization during spindle and phragmoplast development, Required for gamma-tubulin localization during mitosis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the HAUS3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSARLCSLVAELGYEGAGKLDPDSFEWPFQYDDARPILDWICSSLRPSNVLSLAELSLYEQFQRDGKLLEGDDLDQAYDSISAFSSRRNNQEAVFGAEESIKEVRDATLAHKAEALELQRQLRRLQTQYDLLTGQSSALIQGRRARVAATSAVSGQITAIEDSLSARNLQMNGVLGRLASTSQELAHYHSGEEDGIYLAYSDFHAYLAGDSACTKELNQWFAKQLDTGPYRLVAEEGKSKCSWVSLDDTSNMLRDLEKSQHQRVAELQRLRSIFGTSERQWIEAQVENAKQQAILLTLKSQVTSVEAHIHFDLHSLRRKHADLVEEISTLYQKEEKLLSETIPELCWELAQLQDTYILQGDYDLKVMRQELYISKQKVFINHLVNQLARHQFLKLACQLEKKNMLGAFSLLKVIESELQGYLSATRSRVGRCSALIQAASDVQEQGAVDDRDSFLHGVRDLLSIHSNTQAGLSTYVSAPAIIQQIVALQSDLSSLQSDLENSLPDDRNRCINELCTHIQNLQQLLFASSTTAQPILTPWPLMKELDEMGKINSKLSTAVEEVTLEHRNKREIVKHHAKDVELQRRVFVDFFCNPERLRNQVRELNALVRARQASSS", "length": 617, "molWeight": 69725, "crc64": "7ED2EECDF6D57C3F", "md5": "09C10DA4D372F3C0CCF1D18F4E0C443A"}}
{"primaryAccession": "Q0WRY5", "text": "This is Probable serine/threonine-protein kinase PBL7 protein, from Mouse-ear cress, contains 378 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0WRY5", "organism_name": "Mouse-ear cress", "protein_name": "Probable serine/threonine-protein kinase PBL7", "length": 378, "firstPublicDate": "2014-11-26", "FUNCTION": "Serine/threonine-protein kinase involved in the positive regulation of brassinosteroid (BR) signaling and plant growth, Phosphorylates both BSU1 and BSL1 in vitro", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGWIPCSGKSSGRNKTRRNGDHKLDRKSSDCSVSTSEKSRAKSSLSESKSKGSDHIVAQTFTFSELATATRNFRKECLIGEGGFGRVYKGYLASTSQTAAIKQLDHNGLQGNREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEYMPLGSLEDHLHDISPGKQPLDWNTRMKIAAGAAKGLEYLHDKTMPPVIYRDLKCSNILLDDDYFPKLSDFGLAKLGPVGDKSHVSTRVMGTYGYCAPEYAMTGQLTLKSDVYSFGVVLLEIITGRKAIDSSRSTGEQNLVAWARPLFKDRRKFSQMADPMLQGQYPPRGLYQALAVAAMCVQEQPNLRPLIADVVTALSYLASQKFDPLAQPVQGSLFAPGTPPRSKRV", "length": 378, "molWeight": 41672, "crc64": "D34A25EAFA097608", "md5": "03711D063EACDD2E96A57305F1FB85E2"}}
{"primaryAccession": "Q0WUA3", "text": "This is 2-carboxy-1,4-naphthoquinone phytyltransferase, chloroplastic protein, from Mouse-ear cress, contains 382 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0WUA3", "organism_name": "Mouse-ear cress", "protein_name": "2-carboxy-1,4-naphthoquinone phytyltransferase, chloroplastic", "length": 382, "firstPublicDate": "2011-04-05", "FUNCTION": "Involved in the synthesis of phylloquinone (vitamin K1), Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4-naphthoquinone", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the MenA family, Type 2 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVNFVSLCDIKYGFVPKNSTDLFVKRKIHKLPSRGDVITRLPVFGSNARENLNAKPRRNLRVRPIFCKSYGDAAKVYQEEEIPRAKLIWRAIKLPMYSVALVPLTVGASAAYLETGLFLARRYVTLLLSSILIITWLNLSNDVYDFDTGADKNKMESVVNLVGSRTGTLAAAITSLALGVSGLVWTSLNASNIRAILLLASAILCGYVYQCPPFRLSYQGLGEPLCFAAFGPFATTAFYLLLGSSSEMRHLPLSGRVLSSSVLVGFTTSLILFCSHFHQVDGDLAVGKYSPLVRLGTEKGAFVVRWTIRLLYSMLLVLGLTRILPLPCTLMCFLTLPVGNLVSSYVEKHHKDNGKIFMAKYYCVRLHALLGAALSLGLVIAR", "length": 382, "molWeight": 42037, "crc64": "B8E51B6C43BE601B", "md5": "E0E7DBFE030B47FDE9D1327781D06E9A"}}
{"primaryAccession": "Q0WX00", "text": "This is Putative E3 ubiquitin-protein ligase RING1b protein, from Mouse-ear cress, contains 460 amino acids, has 1 RING-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [103, 143], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q0WX00", "organism_name": "Mouse-ear cress", "protein_name": "Putative E3 ubiquitin-protein ligase RING1b", "length": 460, "firstPublicDate": "2010-08-10", "FUNCTION": "As part of the PRC1-like complex, repress class I KNOX gene expression, PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development, PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPSLKSFSAAEEEDDQLGRNSEAERFNPEAVEKEEDPDKMDEKDESGDEEDDVKRDQVEAEDEEALGEEEDSKERSQSSSAGELSESEYMVVDLADICKDVQCSICLGIIRKTRTVMECLHRFCRECIDKSMRLGNNECPTCRKHCASRRSLRDDPNFDALIAALFKNIDKFEEEELNFRQDDEARNKQIQASIAQVSQRQSKALVKRKSVGKGTAILSRSRRSGGGSRRRRNCRNIEQDTSEANDDDDQNKRGKDSSSDEPCERQRKKRSATQPSSSNANNNDNCAGNGTEQTHQRDSRVISPVLVWNSELIAWGRGGTRSNTRQGNNNQGAISKRNARLKRLVEYLGSLEGNSVELDIHLKLVSLDTEGLLNLHEPYLCFRPTLLVKQLREYVARHLKLKAEEVELLVSKDGDTVIGNKTSTEKMQSLQDDETVAKLKVDCISSNGYMIVVYRRKQIA", "length": 460, "molWeight": 51975, "crc64": "A6713D9E8D34A66F", "md5": "A78AA0675DABE6E89D5C83A4B5445432"}}
{"primaryAccession": "Q10109", "text": "This is Lap-Emerin-Man domain protein 2 protein, from Fission yeast, contains 688 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10109", "organism_name": "Fission yeast", "protein_name": "Lap-Emerin-Man domain protein 2", "length": 688, "firstPublicDate": "1996-02-01", "FUNCTION": "Nucleus inner membrane protein involved in meiosis (PubMed:20404563), Plays a role in regulating nuclear envelope (NE) morphology and nuclear integrity, particularly during spindle pole body (SPB) extrusion or insertion through the NE, and perhaps during karyokinesis (PubMed:28242692)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDNWEDPNFELRNLRVIDLKKILHESGVSFPVNARKIEYIRMVDRIRKNKLSSGPQHLLSHLQKEENSNTSKASSSEDEIAPKYLYPSSPSKSTKKPHNETEPLLSPQFIDKPSNIETPVKIESPHVSQNNTFQSYSELSPNVETSLTMKTPPAHASTPKFRSHKSHRVAVPMSFMDSSALHTSPAFSERLKLLSSSNNFSPQLRSPKISHRLQTSATSSPLQHKRPFTNVPERVSRDIEFAPLDSARPSESSSPYSEVDSAEEDDELFQNYVLQQTRKESKLWSFIKKVFHDIKYANYRLLHNLRAFPGISAISSSYLVHIFMILLGVVAAIFLALLREKMFTAGFCDSGASGSSASILGISFPSLCRTCPPNAICPSPNYVECKPGYVLYEPWYSSLGFWPSKYCVSDTSREESVNIFREECLSVLRSWNAILHCSNNSSDLLERNMSYNAHPYVADNLNISSDHISFPSKPFALGLLHDTLLERKSPTLGLEMFEDLFKASLAVLSETNEVVMDSKLICYDSWAGIPLRCRLKQQLIKFVWRNKVFLFGILALSGVIFKLINFFRTRSIVAKYLPSASRFCVESLKRQKANYQMSRSQEPVIPLIEMHDILFHGNGPLEQIHMTKATARTLWEAIVERVEQVGSVRTRESEVDGEWTRVWEWVGTNTLDFQTDRSFINTTSPLRE", "length": 688, "molWeight": 78179, "crc64": "3CB29ED7B7A5DEA2", "md5": "2D8530FE12145594B4DE77F339FCC9D4"}}
{"primaryAccession": "Q10146", "text": "This is Exosome complex exonuclease rrp6 protein, from Fission yeast, contains 777 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10146", "organism_name": "Fission yeast", "protein_name": "Exosome complex exonuclease rrp6", "length": 777, "firstPublicDate": "1996-10-01", "FUNCTION": "Nuclear-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events, In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm, The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes, RRP6 has 3'-5' exonuclease activity which is not modulated upon association with Exo-9 suggesting that the complex inner RNA-binding path is not used to access its active site (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the exosome component 10/RRP6 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDESELFKGLMNSTAYCSELAKVDIPFYKSIDTEFNENIKSVSSRFMRLIELLLSKVDRSRAEDIVDVEDIDNRWAEVSDTLDILFEKADYSIDKAQGLLKKPAIETHASTSDVANKKPKKEKLPYKVIHAAHLTKPQLRFRVQPNNSREFVWSWKLTEKPHSLVPLEKIIAQVKLDPSLKNSLPHPYEPEIQNSVYPPWVSEMSNPIDTGSVDETEPIWVSTESQLSDMLKELQNSKEIAVDLEHHDYRSFRGFVCLMQISNREKDWIVDTLELREELEALNVVFTNPNIIKVFHGATMDIIWLQRDFGLYVVNLFDTYYATKVLGFEGHGLAFLLQKYCDYDADKRYQMADWRIRPLPREMLKYAQSDTHYLLYIWDHLRNELISKSAERKENLMQSVFNSSKQISLRKYELEPYDPIYGLGTDGWRNVLTKFGSSKIIGREALMIYRALHDWRDSVARKEDESVRYVLPNRLLIAIAASKPVEAADVFSISKQLTPIARMYVEDIVKVVQEAEKLYNEQVDREKSQFKEVEKQNQPLAVFSESNTLGDYKVDSSVFEISKQNRSKLKTLLANGSAFWIEGQSQDDLRKARKERLFIVNQNIPFSLTLPCTQGHVESELNVKQSTVTEAANPSLNGEKKQEPIVIRDLGLNKQKRDSSKLNHKEPSNPIEERNEDIEPSEASTSVSKKRKQKKKKKNSGKLTIEAEHVSNDSPIINEAPFDYKNQKNFIADLDSDVGKNKFGKRGFNPLNKVSLPKRNTRELKKRKVSDGKSTSY", "length": 777, "molWeight": 89560, "crc64": "DB1FAC172BFB14A2", "md5": "99A4400BDF8B44F98A513646E79753E5"}}
{"primaryAccession": "Q10425", "text": "This is Eukaryotic translation initiation factor 3 subunit B protein, from Fission yeast, contains 725 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10425", "organism_name": "Fission yeast", "protein_name": "Eukaryotic translation initiation factor 3 subunit B", "length": 725, "firstPublicDate": "1996-10-01", "FUNCTION": "RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome, The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eIF-3 subunit B family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSEILIEEIKDQIVVKDEEIDVSELEVKLNVTKPVGYDTVVVIEGAPVVEEAKQQDFFRFLSSKVLAKIGKVKENGFYMPFEEKNGKKMSLGLVFADFENVDGADLCVQELDGKQILKNHTFVVRKLNQLEKAFSTPDEFSFEEREFKEREHLRSWLTDYYGRDQFISYYGNRVSVNWNRKSDVPEQIVDRENWTETYVQWSPMGTYLVSLHLRGIQLWGGESWGMCARFLHPYVKFVDFSPNEKYLVSWSYEPVRLPPIGHPARETMPFTDDDEGKHCFVWDIASGRILRSFKIPPQPEGSKDGKKVIWPIFKWSADDKYLARVTVGQSISVYETPSLALVDKKTIKIDGVQNFEWCPVSDALGRDSKEQLLAYWTPEITNQPARVALISIPSKSTIRTKNLFNVSDCKLYWQSNGDYLCVKVDRHTKTKKSTFSNLEIFRIREKNIPVEVVDLKDVVLNFAWEPKSDRFAIISANDQVLNSTNVKTNLSFYGFEQKKNTPSTFRHIITFDKKTCNSLFMAPKGRFMVAATLGSSTQYDLEFYDLDFDTEKKEPDALANVQQIGSAEHFGMTELEWDPSGRYVTTSSTIWRHKLENGYRLCDFRGTLLREEMIGEFKQFIWRPRPPSPLTKEDMKKIRKKLKDYNRLFDEEDIAEQSSANRELAARRRQLISEWQKYRDEVIARVAEERAITGQPAITVPAEEEEIIQETVEEVISEEIEPVED", "length": 725, "molWeight": 84035, "crc64": "D4725583F7F9EE34", "md5": "6F88EB4992C5B3FB990354CB28FD6F29"}}
{"primaryAccession": "Q10916", "text": "This is Sphingomyelin phosphodiesterase 1 protein, from Caenorhabditis elegans, contains 564 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10916", "organism_name": "Caenorhabditis elegans", "protein_name": "Sphingomyelin phosphodiesterase 1", "length": 564, "firstPublicDate": "2003-07-19", "FUNCTION": "Sphingomyelin phosphodiesterase (sphingomyelinase) that converts sphingomyelin to ceramide (N-acyl-sphingoid base) and phosphocholine at acidic pH, Displays its enzymatic activity when secreted, May play distinct roles in signaling", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the acid sphingomyelinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRIIYLISTVLLIYTNATVLRTKESIQNKVTYDKYGFQPLCISCTGLISVASFFLKFDVSEPVILEFATIVCKLFAKQPWAVCDGISSQFRDEFFYVFRRLANESPSQICGIILPDCADPTDPSESGWMVALPPKPKRTRISKKKVQKKPNMSMSQNLNVLQLTDLHVDFEYKYPSEANCDDPVCCRVSVSEPKKAAGYWGSVGKCDIPFWTVENMLSHINKTHMIDMVIMTGDYINHVDWEYSIEEHLSVLRKLHRLVQNTFPSTPIYWALGNHEGVPVNSFAPHSVDERFWPTWLYKEFQTMSGPWLSEGAKDSLLKRGSYSTQVMDGLKLITLNTGFCEVTNFFLYLNQSDPDSSMSWFVKELFESEKKGEQVYVLAHIPPGDSECLEGWAFNYYRVIQRFSSTIAAQFFGHDHLDYFTVFYEDMHNVSSKPISVGYASPSVTTFEYQNPAYRIYEIDPYNKFKIVDFTTYYADLEKATEDKKPVWEKLYSARQAHGMDDLSPLSWNKVIQKLFTSEKKREKFYQYAFRNFSPQCDSTCQMQLMCNLRMGHHNSTLYCPTF", "length": 564, "molWeight": 65201, "crc64": "EE3C424B5D905159", "md5": "CB150C2D8734F22AAD70B3A383BD0563"}}
{"primaryAccession": "Q10R09", "text": "This is Protein BIG GRAIN 1 protein, from Rice, contains 310 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10R09", "organism_name": "Rice", "protein_name": "Protein BIG GRAIN 1", "length": 310, "firstPublicDate": "2015-10-14", "FUNCTION": "Involved in auxin transport, Positive regulator of the auxin signaling pathway involved in gravitropism, plant growth and grain development", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the BIG GRAIN 1 (BG1) plant protein family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MERWAAPKVTAGSARRYVADQPSFSSTLLDAIYKSMDEQPGHGGGATGVEAVAAAAKKQHEAALHYGNYYKPSLAGSYRARAPGPHATTSSSSECSSYGGFSSSEAESSHHRRLRPIRTTVPGGAPGPAPEKKAKKPGASIRAKLRDLRKPASPGARLAGFLNSIFAGKRAPATPPSATAGAESACSTASSYSRSCLSKTPSTRGQAKRTVRFLDSDTESLASSTVVDRRRVPVEAVQQMLLQRMEMESDEDDDESSDASSDLFELENFAAIAPAGAAYRDELPVYETTRVALNRAIGHGYGHGRSARVV", "length": 310, "molWeight": 32803, "crc64": "D6BF628FF554C4E3", "md5": "E0CCD3FCA7684F9CC6556C503A6ECCDA"}}
{"primaryAccession": "Q12046", "text": "This is Pre-mRNA-splicing factor CWC2 protein, from Baker's yeast, contains 339 amino acids, has 1 C3H1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [67, 94], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "Q12046", "organism_name": "Baker's yeast", "protein_name": "Pre-mRNA-splicing factor CWC2", "length": 339, "firstPublicDate": "2002-03-05", "FUNCTION": "Involved in the first step of pre-mRNA splicing, Required for cell growth and cell cycle control, Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex, May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA, Associates predominantly with U6 snRNAs in assembled active spliceosomes, Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle, Binds also to U1, U4, U5 and U6 snRNAs and to pre-mRNAs, in vitro, Is not required for the Prp2-mediated remodeling of the activated spliceosome", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RRM CWC2 family", "domain_description": {"C3H1-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTSWRDKSAKVQVKESELPSSIPAQTGLTFNIWYNKWSQGFAGNTRFVSPFALQPQLHSGKTRGDNDGQLFFCLFFAKGMCCLGPKCEYLHHIPDEEDIGKLALRTEVLDCFGREKFADYREDMGGIGSFRKKNKTLYVGGIDGALNSKHLKPAQIESRIRFVFSRLGDIDRIRYVESKNCGFVKFKYQANAEFAKEAMSNQTLLLPSDKEWDDRREGTGLLVKWANEDPDPAAQKRLQEELKLESLNMMVHLINNNTNSAGTEVNNKNNERLDRTFPEASVDNVKKRLLPLDNGMESDDFIEKLKKVKKNISRENISSKPSVGKLGGPLLDYLSSDED", "length": 339, "molWeight": 38431, "crc64": "371734A11DFDB339", "md5": "536CAD9A27F0AA6250FD3EDCAC6A3FEC"}}
{"primaryAccession": "Q12050", "text": "This is Telomere length regulation protein ELG1 protein, from Baker's yeast, contains 791 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12050", "organism_name": "Baker's yeast", "protein_name": "Telomere length regulation protein ELG1", "length": 791, "firstPublicDate": "2005-02-01", "FUNCTION": "Involved in the negative control of telomere length and in telomeric silencing through a replication-mediated pathway, May have a role in Okazaki fragment maturation, Required for S-phase progression, Component of the RFC-like ELG1-RFC complex which appears to have a role in DNA replication, replication fork re-start, recombination and repair", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ELG1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKRHVSLSDILTGNKRKVRRQDALQITIDDENDTESGTFDARTAKHDDSSVIFLNHSVVKPIEAVSTNHKSAKEFLMTKRTKEKCDDDDDDLIVISDKSPKSETNCSKIALSQEHEDDISIISTSRIKSSLLNERASKIKNFLKHETTDTFKRLNSISKLNEIEPPLPLHQSIFPVGDKELSDRSVDIPLPFRTIPPLNHNFLPSDYESLKDKNSASCIPVRYQAPVLLGTNIKRNTTLTWPQLFKPVTLKQVLIEPKLKLRIKNWIETSFHTLEKPTLRNRLLNRINPNKQQGSGDELANFIVPDLEEDENLRPDFYRNGEANSSLSEFVPLMILHGNSIGKKTLIQTIMREIAGDDNSYQIYEVNSNMNRSKKDLLDILLDFTTTHYVKDSSKRKSDYGLVLFNDVDVLFKEHDRGYWAMISKLCEFSRRPLVLTCKDLSLVPSELIALASEQNSLFHTKKISTSTVYAFLTKYLKSLEIEVCDDWLRDVVKQNNADIRKCLMHLQFWCVDTEADLISSKNRLPVLTSTLGSSVKDISQLTDLLSINDVIGQATLNRSMVRQEIDSTTMTPEKVNTFQDQNLDDEMKLKFDYVIDYKLHLNDPNRQPLLPFELNIYQHIQEQLEARYSYVREANHRLDNEYLVNRFKKMTESTLNFLASRIPKYDHLQSARRTRNSKKISDILNQFKGIYNDETLNENAEIDLLSATTQQIKAEINPFVFEIAKSDANVKNENKQIFELHSENVSERRYKDLVYQLSQEGVLKNVWFNADPSIVVRKWEHLHSGFSKNK", "length": 791, "molWeight": 91262, "crc64": "2BF86887238F83FE", "md5": "D6C8A8BF9E38C05A2A265779260DF464"}}
{"primaryAccession": "Q12052", "text": "This is Trimethylguanosine synthase protein, from Baker's yeast, contains 315 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12052", "organism_name": "Baker's yeast", "protein_name": "Trimethylguanosine synthase", "length": 315, "firstPublicDate": "2007-01-09", "FUNCTION": "Catalyzes the two serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure, The enzyme is specific for guanine, and N7 methylation must precede N2 methylation, Hypermethylates the m3G cap on TLC1 telomerase which affects telomere silencing and telomere length regulation, Required for pre-mRNA splicing, pre-rRNA processing and small ribosomal subunit synthesis, Involved in nucleolar structural organization", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the methyltransferase superfamily, Trimethylguanosine synthase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGRTFIHASKIKHAARKRKHHSNFRTLIKLLNNDAYKIESSKPLKNGKLFKYWKNRRRLFSKIDSASIYMTDELWFSVTPERIACFLANFVKACMPNAERILDVFCGGGGNTIQFAMQFPYVYGVDYSIEHIYCTAKNAQSYGVDDRIWLKRGSWKKLVSKQKLSKIKYDCVFGSPPWGGPEYLRNDVYDLEQHLKPMGITKMLKSFLKLSPNVIMFLPRNSDLNQLSRATRKVLGPFAKCKVLYVKENGYMKGIFCMWGECFFNYEPASTENSRRESSEKEELSSENEELSKRKKHESTTTTKDNTVDIYDVNG", "length": 315, "molWeight": 36527, "crc64": "A7E0ABBE915D6CD4", "md5": "652767C807044F0CBE72C772FF093DE4"}}
{"primaryAccession": "Q12118", "text": "This is Small glutamine-rich tetratricopeptide repeat-containing protein 2 protein, from Baker's yeast, contains 346 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12118", "organism_name": "Baker's yeast", "protein_name": "Small glutamine-rich tetratricopeptide repeat-containing protein 2", "length": 346, "firstPublicDate": "2005-11-22", "FUNCTION": "Co-chaperone that binds to the molecular chaperone Hsp70 (SSA1 and SSA2), Regulates Hsp70 ATPase activity (By similarity), Required for recovery from heat shock", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the SGT family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSASKEEIAALIVNYFSSIVEKKEISEDGADSLNVAMDCISEAFGFEREAVSGILGKSEFKGQHLADILNSASRVPESNKKDDAENVEINIPEDDAETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNATEAMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDASQGASAGGLPDLGSLLGGGLGGLMNNPQLMQAAQKMMSNPGAMQNIQKMMQDPSIRQMAEGFASGGGTPNLSDLMNNPALRNMAGNLFGGAGAQSTDETPDNENKQ", "length": 346, "molWeight": 37218, "crc64": "33539B74F742BD3C", "md5": "95E8C0913037EDB11298E1CFC6D9ACA1"}}
{"primaryAccession": "Q12146", "text": "This is DNA replication complex GINS protein PSF3 protein, from Baker's yeast, contains 194 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12146", "organism_name": "Baker's yeast", "protein_name": "DNA replication complex GINS protein PSF3", "length": 194, "firstPublicDate": "2005-03-15", "FUNCTION": "Functions as part of the GINS complex which plays an essential role in the initiation of DNA replication by binding to DNA replication origins and facilitating the assembly of the DNA replication machinery", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the GINS3/PSF3 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGYYDIDDVLADGTEFPCKFQYDIPGLGYLENNPGRPITKNTKLSLPLWLARILAIVGGDEALVDEEPVPFVELLPPDMFSTKVMNAIKTDPVALDLHSINSHFFSLAIKWIMLFSEKELANVVSELLLQRAQELNHHASSLSIDLNADSTGKNSANTNIATSTFLLKLEEMEKEIYKKSHESYKDTKRWMFKK", "length": 194, "molWeight": 21952, "crc64": "3E8B60DFCE16391D", "md5": "B00E4BCF1AF024709FA041E8E50E744B"}}
{"primaryAccession": "Q12168", "text": "This is Glucan endo-1,3-beta-D-glucosidase 2 protein, from Baker's yeast, contains 779 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12168", "organism_name": "Baker's yeast", "protein_name": "Glucan endo-1,3-beta-D-glucosidase 2", "length": 779, "firstPublicDate": "2006-02-07", "FUNCTION": "Cleaves internal linkages in 1,3-beta-glucan", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the glycosyl hydrolase 81 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MCYSRQAIPPPVPNRPGGTTNRGPPPLPPRANVQPPVCSSENSSKPRENRVAGESLRTPSSSNPLADSQVNSDNIFQSPVLSNLKAPPSVFNKVQHPVPKPNIDDQSVDPLETNKFYTNMLLDDNTQPIWTHPYSIWFSRDPELFGLAANHTLASQRVFDTTTNPPRFYFNPTNIKSFVFKAREFVSSNDIKLEFRDMKHMSMCLLMSLSSSQFIEFPLVQGMGFVTAIYHDLGFELRSAVGFRSLERISVNERYGKYNIQLENNRNWILYLTSPDYSFPQDFQISLLDSNTIISSHKINGLICQLSADSVPSIDMAAGCYPVYCDLSGQTVDEHFTNYRFNYTVAGYSQSGTTLMYALPHHKAAFTPEMQEREIASSLDSTVKGLMTGYLTNSFDMQVQVPQELGFEPVALSLNKKADYSQEKLSKIREAAVQEVQLSDPQQESNIDSMYFSGKILAKYAWILYVTHYILHDENLTKELLSKLTIAMERFISNQQVLPLNYDVSWKGIISSGSSSQDFGNSYYNDHHFHYSYHVITAAIISLVDSDLSGVTNNSWLENNRDWVECLIRDYSGVDNDDPYFPQFRSFDWFNGHSWAKGLFPSGDGKDEESTSEDVNSCYAIKLWGLVTGNSKLTDIANLQLGIMRNVFQSYFLYESNNTVQPKEFIGNKVSGILFENKIDHATYFGMEPQYIHMIHAIPITSASSWVRTPNFVKEEWEEKMQPIIDQVNDGWKGIIMLNMALLDPKFSYDFFSQPDFNRNFLDNGQSLTWSLAYSGAFS", "length": 779, "molWeight": 88403, "crc64": "8BCC24DF96414FA7", "md5": "F9D9B17922BEFEC5AA7FA619A1D7894F"}}
{"primaryAccession": "Q12188", "text": "This is Meiotic recombination protein REC8 protein, from Baker's yeast, contains 680 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12188", "organism_name": "Baker's yeast", "protein_name": "Meiotic recombination protein REC8", "length": 680, "firstPublicDate": "2006-12-12", "FUNCTION": "Replaces the SCC1 mitosis-specific cohesin to ensure sister chromatid cohesion during meiosis (PubMed:10412984, PubMed:10691741, PubMed:11081626, PubMed:11163190, PubMed:12101124, PubMed:12663816, PubMed:12665553, PubMed:12717442, PubMed:15062096, PubMed:15120066, PubMed:15819623, PubMed:16027219, PubMed:9784122), Is cleaved by ESP1 shortly before the first meiotic division, and dissociates from chromatin, allowing sister chromatids to segregate (PubMed:11081626), Is protected from cleavage by SPO13 (PubMed:15620644), Promotes localization of the LINC complex subunit MPS3 on nuclear envelope in mitotic cells (PubMed:30417519)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the rad21 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAPLSLNFKDDKKYKGLTTVWLLSALGNSIVKESNNYYSNKSNSTGNISSSTVKKKDIVNISIPKTCDEIQNFENDFSLRYISNLLYGVTICYNKKTEYVLNDLNHLLVQLQKNDVYAFKAKNKSTRINGLNSNNSIIGNKNNNYTWEECVFFDDDPLYDITKVPALEFLNTTLQDNVSFIEEAKSIRRQDYINELSNSNRFELHGDMTNSDAQSNLGSNVRNSFPLDEIPVDVDFNLDLDDIVSHQGTPLGSHSSSQKDGNDFKFNYQGDELVLNFENDNENNSNGGEDTSVENEGPVANLKDYELGLEAQASEEENDLQQKLNTRMQRGHRADVGGQFSKVQFDAKTSYPNEVLKFNHGNYSHLMEKNRIRKLTGQNFLTSNISSLVRSCGEEEFFSTNWLSIFNDFSNIKTSEWDLYPQGFSSVERGRKRAHSLVSTQSSSSTRSHEYGRKSFRNNKNDNYSSDMENDNLLLNLEQINEDLEDGHYIEENSQGNILDFNLNLPPSSFGRSHTRNSTRSSGFNEDIVGALRRRVGPSEQNFAEEDDSSNSCFSDGSQQNLQQDKTNFQDVILDYQTKKFYDYIKERSIVVGRTTRSNPPFKRKMLLVDIIPSRMGEAQTGANFDDVERGVSRQIAASAFLSLLNLATKGMVKLNEYPVADAVTKDLKLRREDEIIVYA", "length": 680, "molWeight": 77202, "crc64": "DCA8F2029724B1B6", "md5": "AFB1C0C53829D34CCB7D88BEBE9AB8F1"}}
{"primaryAccession": "Q12361", "text": "This is G protein-coupled receptor GPR1 protein, from Baker's yeast, contains 961 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12361", "organism_name": "Baker's yeast", "protein_name": "G protein-coupled receptor GPR1", "length": 961, "firstPublicDate": "2002-12-06", "FUNCTION": "Seems to associate with GPA2 and act as G protein-coupled receptor that senses glucose and controls filamentous growth, It acts upstream of adenylate cyclase and is required for glucose activation of cAMP synthesis in concert with a glucose phosphorylation-dependent mechanism", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor GPR1/git3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MITEGFPPNLNALKGSSLLEKRVDSLRQLNTTTVNQLLGLPGMTSTFTAPQLLQLRIIAITASAVSLIAGCLGMFFLSKMDKRRKVFRHDLIAFLIICDFLKAFILMIYPMIILINNSVYATPAFFNTLGWFTAFAIEGADMAIMIFAIHFAILIFKPNWKWRNKRSGNMEGGLYKKRSYIWPITALVPAILASLAFINYNKLNDDSDTTIILDNNNYNFPDSPRQGGYKPWSAWCYLPPKPYWYKIVLSWGPRYFIIIFIFAVYLSIYIFITSESKRIKAQIGDFNHNVLEEEKEKKKLFGLGHWGKAKWYFRSYFKLPLLHLLRNLKNFFTISFIDPNEETDDSGSSNGTFNFGESSNEIPTLFRKTNTGSDENVSASGGVRLLDYNSAKPLDMSKYAMSEQPDLERNNPFDCENDITLNPSELVSKQKEHKVTFSVENEGLDTRKSSMLGHQTFSCQNSLESPLAMYDNKNDNSDITSNIKEKGGIINNNSNNDDDDNNNNNDNDNDNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNIKNNVDNNNTNPADNIPTLSNEAFTPSQQFSQERVNNNADRCENSSFTNVQQHFQAQTYKQMKKRRAQIQKNLRAIFIYPLSYIGIWLFPIIADALQYNHEIKHGPTMWVTYIDTCVRPLSCLVDVIVYLFKEKPWNYSWAKTESKYLIEKYILKGELGEKEILKFCHSNWGKRGWYYRGKWKKRKCWKYSTNPLKRILWFVERFFKQLFELKLHFSFYDNCDDFEYWENYYSAKDSNDNKRTESDETKTNSSDRSLPSNSLELQAMLNNITAEEVEVPLFWRIIHHIPMLGGIDLDELNRLLKIRYNNDHFSLPGLKFALNQNKSHDKHQDVSTNSMVKSSFFSSNIVTNDDENSIEEDKNLRYSDASASENYLVKPTIPGTTPDPIIEAQNDNDSSDSSGIDLIAFLRNGPL", "length": 961, "molWeight": 110709, "crc64": "9889D857872A4209", "md5": "274EADDB52D4B6232F04203EFECA71B7"}}
{"primaryAccession": "Q12373", "text": "This is HAT1-interacting factor 1 protein, from Baker's yeast, contains 385 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12373", "organism_name": "Baker's yeast", "protein_name": "HAT1-interacting factor 1", "length": 385, "firstPublicDate": "2006-03-21", "FUNCTION": "Histone H3 and H4 specific chaperone component of the nuclear histone acetyltransferase B (HAT-B) complex, Involved in chromatin assembly and telomere silencing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the NASP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKLRAEDVLANGTSRHKVQIDMERQVQIAKDLLAQKKFLEAAKRCQQTLDSLPKDGLLPDPELFTIFAQAVYNMEVQNSGNLFGDALLAGDDGSGSESESEPESDVSNGEEGNENGQTEIPNSRMFQFDQEEEDLTGDVDSGDSEDSGEGSEEEEENVEKEEERLALHELANFSPANEHDDEIEDVSQLRKSGFHIYFENDLYENALDLLAQALMLLGRPTADGQSLTENSRLRIGDVYILMGDIEREAEMFSRAIHHYLKALGYYKTLKPAEQVTEKVIQAEFLVCDALRWVDQVPAKDKLKRFKHAKALLEKHMTTRPKDSELQQARLAQIQDDIDEVQENQQHGSKRPLSQPTTSIGFPALEKPLGDFNDLSQLVKKKPRRH", "length": 385, "molWeight": 43428, "crc64": "B280CFCCB6896506", "md5": "5A7DFF754FBE493974C58A1929A5EE3E"}}
{"primaryAccession": "Q12429", "text": "This is Diphthine--ammonia ligase protein, from Baker's yeast, contains 685 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12429", "organism_name": "Baker's yeast", "protein_name": "Diphthine--ammonia ligase", "length": 685, "firstPublicDate": "2006-11-28", "FUNCTION": "Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP, Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor eEF-2 (EFT1 or EFT2) to diphthamide", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "In the N-terminal section; belongs to the Diphthine--ammonia ligase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFIALISGGKDSFYNIFHCLKNNHELIALGNIYPKESEEQELDSFMFQTVGHDLIDYYSKCIGVPLFRRSILRNTSNNVELNYTATQDDEIEELFELLRTVKDKIPDLEAVSVGAILSSYQRTRVENVCSRLGLVVLSYLWQRDQAELMGEMCLMSKDVNNVENDTNSGNKFDARIIKVAAIGLNEKHLGMSLPMMQPVLQKLNQLYQVHICGEGGEFETMVLDAPFFQHGYLELIDIVKCSDGEVHNARLKVKFQPRNLSKSFLLNQLDQLPVPSIFGNNWQDLTQNLPKQQAKTGEQRFENHMSNALPQTTINKTNDKLYISNLQSRKSETVEKQSEDIFTELADILHSNQIPRNHILSASLLIRDMSNFGKINKIYNEFLDLSKYGPLPPSRACVGSKCLPEDCHVQLSVVVDVKNTGKEKINKNKGGLHVQGRSYWAPCNIGPYSQSTWLNDDANQVSFISGQIGLVPQSMEILGTPLTDQIVLALQHFDTLCETIGAQEKLLMTCYISDESVLDSVIKTWAFYCSNMNHRSDLWMDKSDDVEKCLVLVKISELPRGAVAEFGGVTCKRLIVDDNDSDKKEREENDDVSTVFQKLNLNIEGFHNTTVSAFGYNRNFITGFVDSREELELILEKTPKSAQITLYYNPKEIITFHHHIGYYPVEKLFDYRGKEHRFGLHIRS", "length": 685, "molWeight": 77941, "crc64": "E3AA0C948A57ADC2", "md5": "A08D7C387281739DA50CBC940D72DAF6"}}
{"primaryAccession": "Q12462", "text": "This is Peroxisomal membrane protein PMP27 protein, from Baker's yeast, contains 236 amino acids, is membrane-bound, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12462", "organism_name": "Baker's yeast", "protein_name": "Peroxisomal membrane protein PMP27", "length": 236, "firstPublicDate": "1997-11-01", "FUNCTION": "Involved in peroxisomal proliferation, Promotes peroxisome division and biogenesis", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the peroxin-11 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVCDTLVYHPSVTRFVKFLDGSAGREKVLRLLQYLARFLAVQNSSLLARQLQAQFTTVRKFLRFLKPLNHLQAAAKFYDNKLASDNVVRVCNVLKNIFFAAYLSLDQVNLLRILKVIPVTVLTGKKIPRWSNWCWLFGLLSGLAMDLRKIQTSHAQIAAFVKAKSQSQGDEHEDHKKVLGKAYQDRYTALRRLFWDAADSFIVLNNLGYLSSNEEYVALSGVVTSILGMQDMWKAT", "length": 236, "molWeight": 26875, "crc64": "26B95896D57018DD", "md5": "0C21B83A9C1CF82C2B0940F7B2BB4513"}}
{"primaryAccession": "Q12488", "text": "This is DNA replication complex GINS protein PSF1 protein, from Baker's yeast, contains 208 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12488", "organism_name": "Baker's yeast", "protein_name": "DNA replication complex GINS protein PSF1", "length": 208, "firstPublicDate": "2000-05-30", "FUNCTION": "Required for DNA replication, Functions as part of the GINS complex which plays an essential role in the initiation of DNA replication by binding to DNA replication origins and facilitating the assembly of the DNA replication machinery, Required for the chromatin binding of CDC45", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the GINS1/PSF1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MYGDLGNKLVLEAKRTKQLYARSNQDVNLPMYHEDIIRNILKEVSNLRKNTEYLKEQQQLGMLDDKVAKCQYFVTLLCMERNKRCLLAYQRLRTDILDSMAWNNNGLDLMSSITFSQQDTNNLSHQEQEYLKEYCDLITDLKSGDLVDIDLSGSLVPPSDVFIDVRVLKDAGEIQTEYGVFNLIKDSQFFVRQSDVERLIQQGYLQKI", "length": 208, "molWeight": 24204, "crc64": "4667D8152C1AB5B4", "md5": "7A8739A3884AD3AD6F4EDC3420926719"}}
{"primaryAccession": "Q12524", "text": "This is Peroxisomal coenzyme A diphosphatase 1, peroxisomal protein, from Baker's yeast, contains 340 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12524", "organism_name": "Baker's yeast", "protein_name": "Peroxisomal coenzyme A diphosphatase 1, peroxisomal", "length": 340, "firstPublicDate": "1997-11-01", "FUNCTION": "Diphosphatase (pyrophosphatase) with specificity for coenzyme A and CoA derivatives, Catalyzes the hydrolysis of the diphosphate linkage in CoA to give 3',5'-ADP and 4'-phosphopantetheine, Prefers oxidized CoA disulfide (CoASSCoA) over CoA as a substrate, May be required to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids (PubMed:10922370), Can also hydrolyze 8-oxo-dGTP and 2-OH-dATP in vitro; therefore it may function as a sanitizing enzyme for oxidized nucleotides and may contribute to prevention of spontaneous mutagenesis due to the misincorporation of these oxidized nucleotides during DNA synthesis (PubMed:15475388), Shows moderate activity in vitro with several short chain acyl-CoA esters and very low activity on 3'-dephospho-CoA while is not active with (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di- or monophosphates, diadenosine polyphosphates, nucleoside 5'-diphosphosugars, cytidine 5'-diphosphoalcohols, NAD(+), NADH, or FAD (PubMed:10922370)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the Nudix hydrolase family, PCD1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MILSQRRMLSSKQLIENLIRYKFHKTPYTRSSIWPFKRNSAVIILLFIGMKGELRVLLTKRSRTLRSFSGDVSFPGGKADYFQETFESVARREAEEEIGLPHDPEVLHKEFGMKLDNLVMDMPCYLSRTFLSVKPMVCFLYKDKLEKHEDKYKVPLDIRKFFGKLNPGETSSLFSVPLNDLVIHLLPEADEDVKSYQAEYFERKEYKLNWGGIKWLIMHYHFHVANNNEMPWLQTIEDLSSSDEDGVDGGIFRFRDLWGLTCKILFDVSCIANGLMDEKLKGELGHEDLIVGLHDYGNQMQPNGRSEWEIGMINGDRNLKYSDVIPEYYMKHLLECRSLW", "length": 340, "molWeight": 39755, "crc64": "A8900907266564BE", "md5": "63536D90517D52EA507D40EB740D842E"}}
{"primaryAccession": "Q12692", "text": "This is Histone H2A.Z protein, from Baker's yeast, contains 134 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12692", "organism_name": "Baker's yeast", "protein_name": "Histone H2A.Z", "length": 134, "firstPublicDate": "1997-11-01", "FUNCTION": "Variant histone H2A which can replace H2A in some nucleosomes, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received (PubMed:11000274, PubMed:11081628, PubMed:11090616, PubMed:11509669, PubMed:12628191, PubMed:14645854, PubMed:14690608, PubMed:15045029, PubMed:16239142, PubMed:16344463, PubMed:16543223), Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins (PubMed:16543222), Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes (PubMed:11509669), Involved in chromosome stability (PubMed:15353583), Required to target MPS3 to the inner membrane of the nuclear envelope (PubMed:21518795)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGKAHGGKGKSGAKDSGSLRSQSSSARAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDDELDSLIRATIASGGVLPHINKALLLKVEKKGSKK", "length": 134, "molWeight": 14283, "crc64": "1D8FCEE3C8A504E7", "md5": "8D734F032BF737B6EF91CC026208AF62"}}
{"primaryAccession": "Q12706", "text": "This is Serine/threonine-protein kinase psk1 protein, from Fission yeast, contains 436 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12706", "organism_name": "Fission yeast", "protein_name": "Serine/threonine-protein kinase psk1", "length": 436, "firstPublicDate": "2005-02-01", "FUNCTION": "AGC kinase which plays a role in TOR complex 1 (TORC1) signaling pathway which mediates temporal control of cell growth in response to nutrients, Required for phosphorylation of ribosomal protein S6 (rps601/rps602) at 'Ser-235' and 'Ser-236'", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPVFMFDEHDNLNENYNSHLSSDDEIAEEGYDFEELEASASTITSSSDLKDGKNAKDEKGTVEFKVAAHGDFISSKGDNYVPSGKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADCRSFVGTEEYCAPEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPFYVTSDARDIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPCITNPEAAENFSVEFTKLPLSTTPILHEEFGNLTIGSHSSAFQGFTYVASPNFLNCEFLSNNAVSNH", "length": 436, "molWeight": 49321, "crc64": "3498C4BE214530BC", "md5": "89DD730A1BC102B045CA00988EEA8071"}}
{"primaryAccession": "Q12800", "text": "This is Alpha-globin transcription factor CP2 protein, from Human, contains 502 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12800", "organism_name": "Human", "protein_name": "Alpha-globin transcription factor CP2", "length": 502, "firstPublicDate": "2006-03-21", "FUNCTION": "Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters, Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity), Functions as part of the SSP (stage selector protein) complex, Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells, Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the grh/CP2 family, CP2 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAWALKLPLADEVIESGLVQDFDASLSGIGQELGAGAYSMSDVLALPIFKQEESSLPPDNENKILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKLGELPEINGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGIIDPRANPTQLNTVEFLWDPAKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTPHEKEKYQPSYETTILTECSPWPEITYVNNSPSPGFNSSHSSFSLGEGNGSPNHQPEPPPPVTDNLLPTTTPQEAQQWLHRNRFSTFTRLFTNFSGADLLKLTRDDVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESLQLREQQQQQQQQQQKHEDGDSNGTFFVYHAIYLEELTAVELTEKIAQLFSISPCQISQIYKQGPTGIHVLISDEMIQNFQEEACFILDTMKAETNDSYHIILK", "length": 502, "molWeight": 57256, "crc64": "B93825C2687F89FF", "md5": "0E9B490BDD35BE4D5CD42EF8D62124AE"}}
{"primaryAccession": "Q12933", "text": "This is TNF receptor-associated factor 2 protein, from Human, contains 501 amino acids, has 1 RING-type Zinc finger, has 2 TRAF-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [34, 73], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [124, 180], "description": "TRAF-type", "keyword_description": "Zinc finger", "textural_description": "TRAF-type Zinc finger"}, {"location": [177, 233], "description": "TRAF-type", "keyword_description": "Zinc finger", "textural_description": "TRAF-type Zinc finger"}], "meta_data": {"primaryAccession": "Q12933", "organism_name": "Human", "protein_name": "TNF receptor-associated factor 2", "length": 501, "firstPublicDate": "2000-05-30", "FUNCTION": "Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis (PubMed:22212761), Required for normal antibody isotype switching from IgM to IgG, Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1, Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases, Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation; this does not depend on the TRAF2 RING-type zinc finger domain, Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR, In complex with BIRC2 or BIRC3, promotes ubiquitination of IKBKE", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TNF receptor-associated factor family, A subfamily", "domain_description": {"RING-type Zinc finger": 1, "TRAF-type Zinc finger": 2}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL", "length": 501, "molWeight": 55859, "crc64": "C508BE185B783B20", "md5": "3112349E6EB9F0CA7F019C9AE9720195"}}
{"primaryAccession": "Q13148", "text": "This is TAR DNA-binding protein 43 protein, from Human, contains 414 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q13148", "organism_name": "Human", "protein_name": "TAR DNA-binding protein 43", "length": 414, "firstPublicDate": "2002-03-27", "FUNCTION": "RNA-binding protein that is involved in various steps of RNA biogenesis and processing (PubMed:23519609), Preferentially binds, via its two RNA recognition motifs RRM1 and RRM2, to GU-repeats on RNA molecules predominantly localized within long introns and in the 3'UTR of mRNAs (PubMed:23519609, PubMed:24240615, PubMed:24464995), In turn, regulates the splicing of many non-coding and protein-coding RNAs including proteins involved in neuronal survival, as well as mRNAs that encode proteins relevant for neurodegenerative diseases (PubMed:21358640, PubMed:29438978), Plays a role in maintaining mitochondrial homeostasis by regulating the processing of mitochondrial transcripts (PubMed:28794432), Regulates also mRNA stability by recruiting CNOT7/CAF1 deadenylase on mRNA 3'UTR leading to poly(A) tail deadenylation and thus shortening (PubMed:30520513), In response to oxidative insult, associates with stalled ribosomes localized to stress granules (SGs) and contributes to cell survival (PubMed:23398327, PubMed:19765185), Participates also in the normal skeletal muscle formation and regeneration, forming cytoplasmic myo-granules and binding mRNAs that encode sarcomeric proteins (PubMed:30464263), Plays a role in the maintenance of the circadian clock periodicity via stabilization of the CRY1 and CRY2 proteins in a FBXL3-dependent manner (PubMed:27123980), Negatively regulates the expression of CDK6 (PubMed:19760257), Regulates the expression of HDAC6, ATG7 and VCP in a PPIA/CYPA-dependent manner (PubMed:25678563)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQREPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM", "length": 414, "molWeight": 44740, "crc64": "8E09A1206FB4EF4A", "md5": "D21783F4E4F170AA5D52741BC444BF07"}}
{"primaryAccession": "Q13191", "text": "This is E3 ubiquitin-protein ligase CBL-B protein, from Human, contains 982 amino acids, has 1 RING-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [373, 412], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q13191", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase CBL-B", "length": 982, "firstPublicDate": "2000-12-01", "FUNCTION": "E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome, Negatively regulates TCR (T-cell receptor), BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways, In naive T-cells, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production, Also acts by promoting PIK3R1/p85 ubiquitination, which impairs its recruitment to the TCR and subsequent activation, In activated T-cells, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy, In B-cells, acts by ubiquitinating SYK and promoting its proteasomal degradation, Slightly promotes SRC ubiquitination, May be involved in EGFR ubiquitination and internalization, May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3, In association with CBL, required for proper feedback inhibition of ciliary platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway via ubiquitination and internalization of PDGFRA (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPPERPPPIPPDNRLSRHIHHVESVPSRDPPMPLEAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSNVNGRHSRVGSDPVLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFVDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNVEVARSILREFAFPPPVSPRLNL", "length": 982, "molWeight": 109450, "crc64": "B4E307D31B9F0779", "md5": "C7019C29606A0093B008639B481C51C6"}}
{"primaryAccession": "Q13324", "text": "This is Corticotropin-releasing factor receptor 2 protein, from Human, contains 411 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q13324", "organism_name": "Human", "protein_name": "Corticotropin-releasing factor receptor 2", "length": 411, "firstPublicDate": "1997-11-01", "FUNCTION": "G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3, Has high affinity for UCN, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase, Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV", "length": 411, "molWeight": 47688, "crc64": "96B99A93594CF07F", "md5": "99BF0607EF9F0FCA0AADAF0DFDFA73CC"}}
{"primaryAccession": "Q13495", "text": "This is Mastermind-like domain-containing protein 1 protein, from Human, contains 774 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q13495", "organism_name": "Human", "protein_name": "Mastermind-like domain-containing protein 1", "length": 774, "firstPublicDate": "1997-11-01", "FUNCTION": "Transactivates the HES3 promoter independently of NOTCH proteins, HES3 is a non-canonical NOTCH target gene which lacks binding sites for RBPJ", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the mastermind family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTVKRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPAAMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELLEELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFASSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQWHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPFSPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQFGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLIRSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFGNTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQQQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQHGNSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSFAHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP", "length": 774, "molWeight": 83231, "crc64": "F8CDD865CBD86AF7", "md5": "7257D4D51C2ACBA5A420BDFB5BC1931C"}}
{"primaryAccession": "Q14149", "text": "This is MORC family CW-type zinc finger protein 3 protein, from Human, contains 939 amino acids, has 1 CW-type Zinc finger, is soluble, locates in Nucleus.", "functionDomainRange": [{"location": [404, 454], "description": "CW-type", "keyword_description": "Zinc finger", "textural_description": "CW-type Zinc finger"}], "meta_data": {"primaryAccession": "Q14149", "organism_name": "Human", "protein_name": "MORC family CW-type zinc finger protein 3", "length": 939, "firstPublicDate": "1997-11-01", "FUNCTION": "(Microbial infection) May be required for influenza A transcription during viral infection (PubMed:26202233)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"CW-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST", "length": 939, "molWeight": 107113, "crc64": "7DF0EC31936BF5FF", "md5": "4F1A544315CCA59957034C2D207A19BD"}}
{"primaryAccession": "Q14197", "text": "This is Large ribosomal subunit protein mL62 protein, from Human, contains 206 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q14197", "organism_name": "Human", "protein_name": "Large ribosomal subunit protein mL62", "length": 206, "firstPublicDate": "1999-07-15", "FUNCTION": "Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit, Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation, May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the prokaryotic/mitochondrial release factor family, Mitochondrion-specific ribosomal protein mL62 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAATRCLRWGLSRAGVWLLPPPARCPRRALHKQKDGTEFKSIYSLDKLYPESQGSDTAWRVPNGAKQADSDIPLDRLTISYCRSSGPGGQNVNKVNSKAEVRFHLATAEWIAEPVRQKIAITHKNKINRLGELILTSESSRYQFRNLADCLQKIRDMITEASQTPKEPTKEDVKLHRIRIENMNRERLRQKRIHSAVKTSRRVDMD", "length": 206, "molWeight": 23630, "crc64": "663BF52443D41540", "md5": "B00817F76E3DC878A23843781D8AA639"}}
{"primaryAccession": "Q14258", "text": "This is E3 ubiquitin/ISG15 ligase TRIM25 protein, from Human, contains 630 amino acids, has 1 RING-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [13, 54], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q14258", "organism_name": "Human", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "length": 630, "firstPublicDate": "2001-01-24", "FUNCTION": "Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase (PubMed:16352599), Involved in innate immune defense against viruses by mediating ubiquitination of RIGI and IFIH1 (PubMed:17392790, PubMed:30193849, PubMed:33849980, PubMed:29357390, PubMed:31710640), Mediates 'Lys-63'-linked polyubiquitination of the RIGI N-terminal CARD-like region and may play a role in signal transduction that leads to the production of interferons in response to viral infection (PubMed:17392790, PubMed:23950712), Mediates 'Lys-63'-linked polyubiquitination of IFIH1 (PubMed:30193849), Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway (PubMed:16352599, PubMed:17069755), Mediates estrogen action in various target organs (PubMed:22452784), Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784), Plays a role in promoting the restart of stalled replication forks via interaction with the KHDC3L-OOEP scaffold and subsequent ubiquitination of BLM, resulting in the recruitment and retainment of BLM at DNA replication forks (By similarity), Plays an essential role in the antiviral activity of ZAP/ZC3HAV1; an antiviral protein which inhibits the replication of certain viruses, Mechanistically, mediates 'Lys-63'-linked polyubiquitination of ZAP/ZC3HAV1 that is required for its optimal binding to target mRNA (PubMed:28202764, PubMed:28060952), Mediates also the ubiquitination of various substrates implicated in stress granule formation, nonsense-mediated mRNA decay, nucleoside synthesis and mRNA translation and stability (PubMed:36067236)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSICSPK", "length": 630, "molWeight": 70973, "crc64": "EB0AB353F0AD4C80", "md5": "36DC3659BE1AAA4E37AA2E32F691AD4E"}}
{"primaryAccession": "Q14508", "text": "This is WAP four-disulfide core domain protein 2 protein, from Human, contains 124 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q14508", "organism_name": "Human", "protein_name": "WAP four-disulfide core domain protein 2", "length": 124, "firstPublicDate": "1998-07-15", "FUNCTION": "Broad range protease inhibitor", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPACRLGPLAAALLLSLLLFGFTLVSGTGAEKTGVCPELQADQNCTQECVSDSECADNLKCCSAGCATFCSLPNDKEGSCPQVNINFPQLGLCRDQCQVDSQCPGQMKCCRNGCGKVSCVTPNF", "length": 124, "molWeight": 12993, "crc64": "9536B00B385259AD", "md5": "BA2DC62E7E931387975509DA80B7BE28"}}
{"primaryAccession": "Q14680", "text": "This is Maternal embryonic leucine zipper kinase protein, from Human, contains 651 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q14680", "organism_name": "Human", "protein_name": "Maternal embryonic leucine zipper kinase", "length": 651, "firstPublicDate": "2004-07-19", "FUNCTION": "Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation, Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622, Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1, Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis, Plays a key role in cell proliferation and carcinogenesis, Required for proliferation of embryonic and postnatal multipotent neural progenitors, Phosphorylates and inhibits BCL2L14, possibly leading to affect mammary carcinogenesis by mediating inhibition of the pro-apoptotic function of BCL2L14, Also involved in the inhibition of spliceosome assembly during mitosis by phosphorylating ZNF622, thereby contributing to its redirection to the nucleus, May also play a role in primitive hematopoiesis", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLRLSSFSCGQASATPFTDIKSNNWSLEDVTASDKNYVAGLIDYDWCEDDLSTGAATPRTSQFTKYWTESNGVESKSLTPALCRTPANKLKNKENVYTPKSAVKNEEYFMFPEPKTPVNKNQHKREILTTPNRYTTPSKARNQCLKETPIKIPVNSTGTDKLMTGVISPERRCRSVELDLNQAHMEETPKRKGAKVFGSLERGLDKVITVLTRSKRKGSARDGPRRLKLHYNVTTTRLVNPDQLLNEIMSILPKKHVDFVQKGYTLKCQTQSDFGKVTMQFELEVCQLQKPDVVGIRRQRLKGDAWVYKRLVEDILSSCKV", "length": 651, "molWeight": 74642, "crc64": "57F05CDC6122E570", "md5": "6B8130CBABD4A6CF226098056D1E81C3"}}
{"primaryAccession": "Q14832", "text": "This is Metabotropic glutamate receptor 3 protein, from Human, contains 879 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q14832", "organism_name": "Human", "protein_name": "Metabotropic glutamate receptor 3", "length": 879, "firstPublicDate": "1997-11-01", "FUNCTION": "G-protein coupled receptor for glutamate, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, Signaling inhibits adenylate cyclase activity", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKMLTRLQVLTLALFSKGFLLSLGDHNFLRREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAASRANASFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQCSLQNKRNHRRVCDKHLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGHWAETLSLDVNSIHWSRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLADEFTCMDCGSGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVVTVFIKHNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRETVILKCNVKDSSMLISLTYDVILVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNVVTHRLHLNRFSVSGTGTTYSQSSASTYVPTVCNGREVLDSTTSSL", "length": 879, "molWeight": 98879, "crc64": "7EB84521676E8304", "md5": "93450475C12B0A00016C89FFF6801EFC"}}
{"primaryAccession": "Q14833", "text": "This is Metabotropic glutamate receptor 4 protein, from Human, contains 912 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q14833", "organism_name": "Human", "protein_name": "Metabotropic glutamate receptor 4", "length": 912, "firstPublicDate": "1997-11-01", "FUNCTION": "G-protein coupled receptor for glutamate, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, Signaling inhibits adenylate cyclase activity", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI", "length": 912, "molWeight": 101868, "crc64": "4A2F36E63A2EAF5A", "md5": "A44869569B55CA54E415B11B3C4DFA86"}}
{"primaryAccession": "Q14CX7", "text": "This is N-alpha-acetyltransferase 25, NatB auxiliary subunit protein, from Human, contains 972 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q14CX7", "organism_name": "Human", "protein_name": "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "length": 972, "firstPublicDate": "2007-07-10", "FUNCTION": "Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln, May play a role in normal cell-cycle progression", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the MDM20/NAA25 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATRGHVQDPNDRRLRPIYDYLDNGNNKMAIQQADKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQSISAQDENLSKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRLLLKNSDDWQFYLTYFDSVFRLIEEAWSPPAEGEHSLEGEVHYSAEKAVKFIEDRITEESKSSRHLRGPHLAKLELIRRLRSQGCNDEYKLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPATQCTKFINQLLGVVPLSTPTEDKLALPADIRALQQHLCVVQLTRLLGLYHTMDKNQKLSVVRELMLRYQHGLEFGKTCLKTELQFSDYYCLLAVHALIDVWRETGDETTVWQALTLLEEGLTHSPSNAQFKLLLVRIYCMLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAESLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTSLAESIKSMNLRPEEDDIPWEDLRDNRDLNVFFSWDPKDRDVSEEHKKLSLEEETLWLRIRSLTLRLISGLPSLNHPVEPKNSEKTAENGVSSRIDILRLLLQQLEATLETGKRFIEKDIQYPFLGPVPTRMGGFFNSGCSQCQISSFYLVNDIYELDTSGLEDTMEIQERIENSFKSLLDQLKDVFSKCKGDLLEVKDGNLKTHPTLLENLVFFVETISVILWVSSYCESVLRPYKLNLQKKKKKKKETSIIMPPVFTSFQDYVTGLQTLISNVVDHIKGLETHLIALKLEELILEDTSLSPEERKFSKTVQGKVQSSYLHSLLEMGELLKKRLETTKKLKI", "length": 972, "molWeight": 112292, "crc64": "232B8FD14447DDD6", "md5": "97CAC68AF3C497E63EC08023746987EB"}}
{"primaryAccession": "Q15042", "text": "This is Rab3 GTPase-activating protein catalytic subunit protein, from Human, contains 981 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q15042", "organism_name": "Human", "protein_name": "Rab3 GTPase-activating protein catalytic subunit", "length": 981, "firstPublicDate": "2005-04-12", "FUNCTION": "Catalytic subunit of the Rab3 GTPase-activating (Rab3GAP) complex composed of RAB3GAP1 and RAB3GAP2, which has GTPase-activating protein (GAP) activity towards various Rab3 subfamily members (RAB3A, RAB3B, RAB3C and RAB3D), RAB5A and RAB43, and guanine nucleotide exchange factor (GEF) activity towards RAB18 (PubMed:9030515, PubMed:10859313, PubMed:24891604), As part of the Rab3GAP complex, acts as a GAP for Rab3 proteins by converting active RAB3-GTP to the inactive form RAB3-GDP (PubMed:10859313), Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones (PubMed:15696165), The Rab3GAP complex, acts as a GEF for RAB18 by promoting the conversion of inactive RAB18-GDP to the active form RAB18-GTP (PubMed:24891604), Required for recruiting and activating RAB18 at the endoplasmic reticulum (ER) membrane where it maintains proper ER structure (PubMed:24891604), Required for normal eye and brain development (PubMed:15696165, PubMed:23420520), May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters (PubMed:9030515, PubMed:9852129)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the Rab3-GAP catalytic subunit family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKGIFTSGTWEEKSDEISFADFKFSVTHHYLVQESTDKEGKDELLEDVVPQSMQDLLGMNNDFPPRAHCLVRWYGLREFVVIAPAAHSDAVLSESKCNLLLSSVSIALGNTGCQVPLFVQIHHKWRRMYVGECQGPGVRTDFEMVHLRKVPNQYTHLSGLLDIFKSKIGCPLTPLPPVSIAIRFTYVLQDWQQYFWPQQPPDIDALVGGEVGGLEFGKLPFGACEDPISELHLATTWPHLTEGIIVDNDVYSDLDPIQAPHWSVRVRKAENPQCLLGDFVTEFFKICRRKESTDEILGRSAFEEEGKETADITHALSKLTEPASVPIHKLSVSNMVHTAKKKIRKHRGVEESPLNNDVLNTILLFLFPDAVSEKPLDGTTSTDNNNPPSESEDYNLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGPPDLRCCLLHQKLQMLNCCIERKKARDEGKKTSASDVTNIYPGDAGKAGDQLVPDNLKETDKEKGEVGKSWDSWSDSEEEFFECLSDTEELKGNGQESGKKGGPKEMANLRPEGRLYQHGKLTLLHNGEPLYIPVTQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMESFKAANPGCSLEDFVRWYSPRDYIEEEVIDEKGNVVLKGELSARMKIPSNMWVEAWETAKPIPARRQRRLFDDTREAEKVLHYLAIQKPADLARHLLPCVIHAAVLKVKEEESLENISSVKKIIKQIISHSSKVLHFPNPEDKKLEEIIHQITNVEALIARARSLKAKFGTEKCEQEEEKEDLERFVSCLLEQPEVLVTGAGRGHAGRIIHKLFVNAQRAAAMTPPEEELKRMGSPEERRQNSVSDFPPPAGREFILRTTVPRPAPYSKALPQRMYSVLTKEDFRLAGAFSSDTSFF", "length": 981, "molWeight": 110524, "crc64": "0673611C5C49641C", "md5": "888AC39111FEC778A68B3A73306242FD"}}
{"primaryAccession": "Q15070", "text": "This is Mitochondrial inner membrane protein OXA1L protein, from Human, contains 435 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q15070", "organism_name": "Human", "protein_name": "Mitochondrial inner membrane protein OXA1L", "length": 435, "firstPublicDate": "2001-02-21", "FUNCTION": "Required for the insertion of integral membrane proteins into the mitochondrial inner membrane, Essential for the activity and assembly of cytochrome oxidase, Required for the correct biogenesis of ATP synthase and complex I in mitochondria", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the OXA1/ALB3/YidC family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAMGLMCGRRELLRLLQSGRRVHSVAGPSQWLGKPLTTRLLFPVAPCCCRPHYLFLAASGPRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGETADVVQTAAEQSFAELGLGSYTPVGLIQNLLEFMHVDLGLPWWGAIAACTVFARCLIFPLIVTGQREAARIHNHLPEIQKFSSRIREAKLAGDHIEYYKASSEMALYQKKHGIKLYKPLILPVTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYILPLAVTATMWAVLELGAETGVQSSDLQWMRNVIRMMPLITLPITMHFPTAVFMYWLSSNLFSLVQVSCLRIPAVRTVLKIPQRVVHDLDKLPPREGFLESFKKGWKNAEMTRQLREREQRMRNQLELAARGPLRQTFTHNPLLQPGKDNPPNIPSSSSKPKSKYPWHDTLG", "length": 435, "molWeight": 48548, "crc64": "CE959F07BCC56041", "md5": "8C23A4AD4E92F6ACD8AC1C221E8BA498"}}
{"primaryAccession": "Q15582", "text": "This is Transforming growth factor-beta-induced protein ig-h3 protein, from Human, contains 683 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q15582", "organism_name": "Human", "protein_name": "Transforming growth factor-beta-induced protein ig-h3", "length": 683, "firstPublicDate": "1997-11-01", "FUNCTION": "Plays a role in cell adhesion (PubMed:8024701), May play a role in cell-collagen interactions (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRKYFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQLYTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTITNNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVFKDGTPPIDAHTRNLLRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCIAAHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVFAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQASAFSRASQRSVRLAPVYQKLLERMKH", "length": 683, "molWeight": 74681, "crc64": "40FDC8A71EBB3D00", "md5": "25482E2E7E165833A423CD22BE36DE6B"}}
{"primaryAccession": "Q16719", "text": "This is Kynureninase protein, from Human, contains 465 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q16719", "organism_name": "Human", "protein_name": "Kynureninase", "length": 465, "firstPublicDate": "1998-12-15", "FUNCTION": "Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively, Has a preference for the L-3-hydroxy form, Also has cysteine-conjugate-beta-lyase activity", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the kynureninase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEKRGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN", "length": 465, "molWeight": 52352, "crc64": "BDD136BE18C79EBB", "md5": "578C0AAB604F3AC23388EE0A1659D606"}}
{"primaryAccession": "Q16740", "text": "This is ATP-dependent Clp protease proteolytic subunit, mitochondrial protein, from Human, contains 277 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q16740", "organism_name": "Human", "protein_name": "ATP-dependent Clp protease proteolytic subunit, mitochondrial", "length": 277, "firstPublicDate": "1998-07-15", "FUNCTION": "Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process, Has low peptidase activity in the absence of CLPX, The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates (PubMed:11923310, PubMed:15522782), Cleaves PINK1 in the mitochondrion (PubMed:22354088)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the peptidase S14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MWPGILVGGARVASCRYPALGPRLAAHFPAQRPPQRTLQNGLALQRCLHATATRALPLIPIVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPNSRIMIHQPSGGARGQATDIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQDGEDEPTLVQKEPVEAAPAAEPVPAST", "length": 277, "molWeight": 30180, "crc64": "B03AAC5D50F7880E", "md5": "101F80DC03E70D83A453345204B6EC30"}}
{"primaryAccession": "Q16853", "text": "This is Membrane primary amine oxidase protein, from Human, contains 763 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q16853", "organism_name": "Human", "protein_name": "Membrane primary amine oxidase", "length": 763, "firstPublicDate": "1997-11-01", "FUNCTION": "Cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion, Has semicarbazide-sensitive (SSAO) monoamine oxidase activity, May play a role in adipogenesis", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the copper/topaquinone oxidase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDIDQMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSWSLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN", "length": 763, "molWeight": 84622, "crc64": "58AD55605EC9D228", "md5": "77E2DAA9322949B2296D0EC339960D1E"}}
{"primaryAccession": "Q16891", "text": "This is MICOS complex subunit MIC60 protein, from Human, contains 758 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q16891", "organism_name": "Human", "protein_name": "MICOS complex subunit MIC60", "length": 758, "firstPublicDate": "2003-03-28", "FUNCTION": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane, Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MICOS complex subunit Mic60 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRACQLSGVTAAAQSCLCGKFVLRPLRPCRRYSTSGSSGLTTGKIAGAGLLFVGGGIGGTILYAKWDSHFRESVEKTIPYSDKLFEMVLGPAAYNVPLPKKSIQSGPLKISSVSEVMKESKQPASQLQKQKGDTPASATAPTEAAQIISAAGDTLSVPAPAVQPEESLKTDHPEIGEGKPTPALSEEASSSSIRERPPEEVAARLAQQEKQEQVKIESLAKSLEDALRQTASVTLQAIAAQNAAVQAVNAHSNILKAAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKSVIENAKKKEVAGAKPHITAAEGKLHNMIVDLDNVVKKVQAAQSEAKVVSQYHELVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVEAIKANCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQLKPPPELCPEDINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGTTQVQPE", "length": 758, "molWeight": 83678, "crc64": "357F25DCABB02E50", "md5": "4DD011F0D70E4075AFFCF468396716FD"}}
{"primaryAccession": "Q18685", "text": "This is Protein unc-112 protein, from Caenorhabditis elegans, contains 720 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q18685", "organism_name": "Caenorhabditis elegans", "protein_name": "Protein unc-112", "length": 720, "firstPublicDate": "2004-01-16", "FUNCTION": "Component of an integrin containing attachment complex, which is required for muscle development and maintenance (PubMed:22253611), Probable regulator of cell-extracellular matrix adhesion (PubMed:10893272), Required during initial muscle assembly to form dense bodies and M-lines (PubMed:10893272)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the kindlin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAHLVEGTSIIDGKWQLPILVTDLNIQRSISVLGNLNVGGLMLELVSECDVERDWSDHALWWPEKRRWLQHTRSTLDQNGITAETQLEFTPMHKEARIQLPDMQMIDARVDFSVNSFKATKKLCRDLGIRYSEELSLKRYIPPEDLRRGTSDADNMNGPLSMRPGEESVGPMTLRKAAPIFASQSNLDMRRRGQSPALSQSGHIFNAHEMGTLPRHGTLPRGVSPSPGAYNDTMRRTPIMPSISFSEGLENEQFDDALIHSPRLAPSRDTPVFRPQNYVEKAAINRGWLDSSRSLMEQGIFEGDIILLRFKFMNFFDLNPKYDPVRINQLYEQAKWSILLDEFDHTEEEATLFAALQLQATLQRDSPEPEENNKDDVDILLDELEQNLDAAALNRRSDLTQVPELADYLKYMKPKKLAAFKGFKRAFFSFRDLYLSYHQSSSDVNSAPLGHFSLKGCEVSQDVSVGQQKYHIKLLLPTAEGMIDFILKCDSEHQYARWMAACRLASRGKSMADSSYQQEVESIKNLLKMQSGNGNENGNSNTASRKAAAVKLPNDFNVDEYISSKYVRRARSKQQIQQRVSDAHGNVRQLTATEAKLQYIRAWQALPEHGIHYFIVRFRNARKAELVAVAVNRLAKLNMDNGESLKTWRFANMKKWHVNWEIRHLKIQFEDEDIEFKPLSADCKVVHEFIGGYIFLSMRSKEHSQNLDEELFHKLTGGWA", "length": 720, "molWeight": 82355, "crc64": "663CB0E9891C1A12", "md5": "94EAC89419A1A1B5CAFA79934FE73EBB"}}
{"primaryAccession": "Q1EHB4", "text": "This is Sodium-coupled monocarboxylate transporter 2 protein, from Human, contains 618 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q1EHB4", "organism_name": "Human", "protein_name": "Sodium-coupled monocarboxylate transporter 2", "length": 618, "firstPublicDate": "2008-05-20", "FUNCTION": "Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter (PubMed:17692818), Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate (By similarity), May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine, May play also a role in monocarboxylates transport in the retina (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the sodium:solute symporter (SSF) (TC 2,A,21) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEVKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGCIVAGVIISLITGRQRGEDIQPLLIRPVCNLFCFWSKKYKTLCWCGVQHDSGTEQENLENGSARKQGAESVLQNGLRRESLVHVPGYDPKDKSYNNMAFETTHF", "length": 618, "molWeight": 67647, "crc64": "01D5F954BD28EF6F", "md5": "A9E7FCE25E81C30675C9A3E08CCC4701"}}
{"primaryAccession": "Q1G3I2", "text": "This is B-box domain protein 30 protein, from Mouse-ear cress, contains 117 amino acids, has 1 B box-type; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [27, 73], "description": "B box-type; atypical", "keyword_description": "Zinc finger", "textural_description": "B box-type; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q1G3I2", "organism_name": "Mouse-ear cress", "protein_name": "B-box domain protein 30", "length": 117, "firstPublicDate": "2016-06-08", "FUNCTION": "Developmental regulator acting by forming heterodimeric complexes, that sequester CO and CO-like (COL) proteins into non-functional complexes, Engages CO and the transcriptional repressor TPL in a tripartite complex, Involved in the CO-mediated long-day flowering-promotion pathway", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"B box-type; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MCRGFEKEEERRSDNGGCQRLCTESHKAPVSCELCGENATVYCEADAAFLCRKCDRWVHSANFLARRHLRRVICTTCRKLTRRCLVGDNFNVVLPEIRMIARIEEHSSDHKIPFVFL", "length": 117, "molWeight": 13562, "crc64": "18C42029A49AFCE7", "md5": "A782000D9C8618662226C82976EEA047"}}
{"primaryAccession": "Q1HG44", "text": "This is Dual oxidase maturation factor 2 protein, from Human, contains 320 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q1HG44", "organism_name": "Human", "protein_name": "Dual oxidase maturation factor 2", "length": 320, "firstPublicDate": "2006-12-12", "FUNCTION": "Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2, May play a role in thyroid hormone synthesis", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DUOXA family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTLWNGVLPFYPQPRHAAGFSVPLLIVILVFLALAASFLLILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSAEWFVGTVNTNTSYKAFSAARVTARVRLLVGLEGINITLTGTPVHQLNETIDYNEQFTWRLKENYAAEYANALEKGLPDPVLYLAEKFTPSSPCGLYHQYHLAGHYASATLWVAFCFWLLSNVLLSTPAPLYGGLALLTTGAFALFGVFALASISSVPLCPLRLGSSALTTQYGAAFWVTLATGVLCLFLGGAVVSLQYVRPSALRTLLDQSAKDCSQERGGSPLILGDPLHKQAALPDLKCITTNL", "length": 320, "molWeight": 34787, "crc64": "5B2F58E575A30E72", "md5": "A94E9C69612928D613FB6DA901624ECA"}}
{"primaryAccession": "Q1MX22", "text": "This is FMRFamide-related peptides protein, from Silk moth, contains 177 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q1MX22", "organism_name": "Silk moth", "protein_name": "FMRFamide-related peptides", "length": 177, "firstPublicDate": "2010-04-20", "FUNCTION": "Regulates ecdysteroidogenesis by direct innervation of the prothoracic gland by reducing cAMP production via the receptor for myosuppressin, The neurons that innervate the prothoracic gland during the fifth instar are most active during days 0-4, after which they reduce and then peak again on day 6, Expression suppresses the biosynthesis of steroid hormones called ecdysteroids that elicit molting and metamorphosis", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the FARP (FMRFamide related peptide) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNHPRSIAMLAALWLVVSVTSTPVRRSPDLEARRRSAIDRSMIRFGRSTLPVVPPAQPSFLQRYSAPQPAALTADDLMTFLRAYEEDYSSPVSKKSASFVRFGRDPSFIRFGRSVDEENSGYQAETNTYPQRRHRARNHFIRLGRDNELSESNDEDRYEVESERTKRSVVDPCNDCA", "length": 177, "molWeight": 20258, "crc64": "5656A5CA1B3F712C", "md5": "FD158720A8128677CCDAB77EB9A53A7E"}}
{"primaryAccession": "Q20748", "text": "This is ATPase family AAA domain-containing protein 3 protein, from Caenorhabditis elegans, contains 595 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q20748", "organism_name": "Caenorhabditis elegans", "protein_name": "ATPase family AAA domain-containing protein 3", "length": 595, "firstPublicDate": "2012-10-03", "FUNCTION": "Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level (PubMed:19888333), Important during development for the up-regulation of mitochondrial activity during the transition to higher larval stages (PubMed:19888333), Regulates mitochondrial iron homeostasis (PubMed:26427876), May play an important role in mitochondrial protein synthesis (By similarity), May also participate in mitochondrial DNA replication (By similarity), May bind to mitochondrial DNA D-loops and contribute to nucleoid stability (By similarity), Plays a role in regulating the production of reactive oxygen species in response to heat stress (PubMed:22245785)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the AAA ATPase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSWLFGVQKNATPQIPDDFQAGAAPGGPQQPGQGQRQEGNSKMAYSFDSTALERAAKAARDLEKFPNAKEALELSRMQEVTRQKEVENETKKIEAQLANMKSEHIRVAEEERRKTLGEETKHAHSRAEYQDQLARKRAEEELAMKARMQEESLRKQEESVKKQEQLRKQTIEHELALKHKYELEKIDAETRARAKAARDNRDVNLEQMKLHEEENRKTVIEKIKTSGELIGSGLNQFLNDKTKIAAAVGGLTALAVGWYTAKRGTGVTARYIESRLGKPSLVRETSRITPLEVLKHPIKSVQMMTRQKKDPLNGVVLPPALERRLRDIAITTSNTKRNNGLFRNVMFYGPPGTGKTLFAKSLAQHSGLDYAVLTGGDIAPLGRDGVSAIHKVFDWASKSRKGLIVFIDEADAFLQKRSKNGMSEDTRAALNAFLFRTGEQSRKFMLVVASNQPEQFDWAVNDRFDQLVEFTLPGMEERERILLQYFNEHIVTPATSGSRSQRLKLDNFDWVAKCNEVAKKTSGMSGRELSKLVIGWQASAYASETGVLTEAIVDRNTADAMVQHEHKMEWLEKEQLKARNQEVKFGTTLKRETAV", "length": 595, "molWeight": 67147, "crc64": "5A7A2B44F46C4D23", "md5": "5F9C931F9DB97B5C21ACEA1ABE504537"}}
{"primaryAccession": "Q22866", "text": "This is Tropomyosin isoforms a/b/d/f protein, from Caenorhabditis elegans, contains 284 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q22866", "organism_name": "Caenorhabditis elegans", "protein_name": "Tropomyosin isoforms a/b/d/f", "length": 284, "firstPublicDate": "2004-02-16", "FUNCTION": "Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction (PubMed:9113409, PubMed:11901171), Involved in muscle actin filament organization and muscle arm extension and morphology (PubMed:15930100), Protects actin filaments from depolymerization by unc-60 in vitro (PubMed:17684058), Also has a role in male mating behavior by regulating the copulatory spicules (PubMed:16399684), Binds to F-actin (PubMed:11901171)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the tropomyosin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDAIKKKMQAMKIEKDNALDRADAAEEKVRQITEKLERVEEELRDTQKKMTQTGDDLDKAQEDLSAATSKLEEKEKTVQEAEAEVASLNRRMTLLEEELERAEERLKIATEKLEEATHNVDESERVRKVMENRSLQDEERANTVEAQLKEAQLLAEEADRKYDEVARKLAMVEADLERAEERAEAGENKIVELEEELRVVGNNLKSLEVSEEKALQREDSYEEQIRTVSSRLKEAETRAEFAERSVQKLQKEVDRLEDELVHEKERYKTISEELDSTFQELSGY", "length": 284, "molWeight": 33004, "crc64": "02271C870E23D2AB", "md5": "C5812C1B2C2FF53BDC19697817E028DF"}}
{"primaryAccession": "Q23255", "text": "This is Double-strand break repair protein mre-11 protein, from Caenorhabditis elegans, contains 728 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q23255", "organism_name": "Caenorhabditis elegans", "protein_name": "Double-strand break repair protein mre-11", "length": 728, "firstPublicDate": "2003-09-19", "FUNCTION": "Required for meiotic crossing over and chiasma formation, Pachytene morphology and homolog pairing are normal, Vital in long term for maintenance of reproductive capacity of subsequent generations", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MRE11/RAD32 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MCGSDDSFDDFVPDSQEPASSRTRNQDHLDDDEVPCSQRPDAANDTMVEDLDEGDEPAHDESEDIIKILVATDIHCGYGENKANIHMDAVNTFEEVLQIATEQKVDMILLGGDLFHENNPSREVQHRVTQLLRQYCLNGNPIALEFLSDASVNFNQSVFGHVNYYDQNLNVGLPIFTIHGNHDDLSGKGLTALDLLHESGLVNLFGKHSNIQEFIVSPILLRKGETRLALYGIGSQRDDRLVRAFKNNSISFLRPNAGAEDWFNLFVLHQNRPRRAMHRSTGNFLPESLIPQFFDLLIWGHEHECKPDPQYVASSEAVGDGFYILQPGSTVATSLTPEEALQKNAFLIKIKGRKFASKPIPLQTVRPMVCDELLLDKIPPGSRPILKTDRPKHTDGRYIDEIAIEAKINEMITTAKAKRRPRQPELPLIRLKVIYDGDWLNITPANAKRIGLRYENVVANAVDMVFIKKNNKPKEGKLQTENEKNITEMADEMGQVSATNLQTIINDYFINQPLVDQMTVLKPIGIGRALEQYSAIEEGGLATSANRNFDSCLMHQIDVVRKTLKKMPLPPINDPSDLDKFRDLITKDLYDMKKADSERFKNPVADVEMEEDEDDPQYYMPPQSTSRTNYASGSEDEVANSDEEMGSSISRHSKQPTTRGRGRGARGAGASRETTRGRSNKVVSTRQIDSDGFEIINDSPSPPPASRSTRGKARGKSAPSKKRDLSFF", "length": 728, "molWeight": 81559, "crc64": "E86C5BEF81216DC9", "md5": "797E1A5AF5C26F6E64F967152EC9362D"}}
{"primaryAccession": "Q23498", "text": "This is Sphingomyelin phosphodiesterase 2 protein, from Caenorhabditis elegans, contains 618 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q23498", "organism_name": "Caenorhabditis elegans", "protein_name": "Sphingomyelin phosphodiesterase 2", "length": 618, "firstPublicDate": "2003-07-19", "FUNCTION": "Sphingomyelin phosphodiesterase (sphingomyelinase) that converts sphingomyelin (N-acyl-sphingoid-1-phosphocholine) to ceramide (N-acyl-sphingoid base) and phosphocholine at acidic pH, Displays its enzymatic activity when secreted, May play distinct roles in signaling", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the acid sphingomyelinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQQPLIILGIGIVLALVSNVESGVLRKPVDEHEYEKWTNARGNEAAVPPPKYKMLRYAKKAINEPENRKMSCLFCTFAVDGVQALIAQNSTDNEIAAFLVNLCDLFDVEQPHVCKNIIYAFKDEVVFVLERSVFTPEEICGAFIANCGHSDKPLTHMWNITIPGGKPPIKPWPKIPDNKPTFKVLHLSDIHIDHQYVVGTEAYCQLDSALGTYAMCCRDYSQDSQGAPTNLKDKPIYVPAGPWGMPYLCDLPYQTFESAMKHISKTFKDLDYIIITGDFEAHDSWDYTEDLTRENMNNMTNVFLEYFPGVPVYVSIGNHEGVPQDAMAPHTMPEYDTRGPQWLYKIMSEMWSHWIPQEALDTVQYRASYAVYPKPGLKLISLNTIYCSEFNFYLYVNEVDPDATLEWLIEELQDSENKGELVHIISHIPPGDNYCLKGWSWNFFEIVKRYENTIAQMFYGHTHYDQFMVYYDMDDPNRRPFHFNWISPSLTTYDWLNPAYRIYEIDGGYEGATYTVKDAKTYFANVTEANMKNKEPEWVLSYDTREHYQMADFSPQSWSDLSDKLWTNTTLFRDYVRLYYRNHYNNECYTDYKCRYTFVCDIKKGRSYDESFCDHLTK", "length": 618, "molWeight": 71925, "crc64": "CF24C82DC09BA115", "md5": "855AD357F53DF9254F4C36E31C4B4B28"}}
{"primaryAccession": "Q23917", "text": "This is 3',5'-cyclic-nucleotide phosphodiesterase regA protein, from Social amoeba, contains 793 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q23917", "organism_name": "Social amoeba", "protein_name": "3',5'-cyclic-nucleotide phosphodiesterase regA", "length": 793, "firstPublicDate": "1998-07-15", "FUNCTION": "Phosphodiesterase specific for cAMP, Involved in the degradation of intracellular cAMP, Morphological suppressor of tagB, Phosphorelay protein that accepts phosphate from rdeA or supplies phosphate from regA; depending on the relative concentration of the phosphodonor proteins", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the cyclic nucleotide phosphodiesterase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNNKQEEIDQFLSSTSTSPSPSSSSSPSNNDSTSLKSMISGIENLNVHSKGNDNKNNNNNNNNNNSNNNEKQKDIVSLENNSSSNNTTTTTTTTTTSNHNSNNNSNNNNNNINNNNINNNNYEPLVNGHNNGFGDKLNDQPSPSSHRVSDFSDEYSPSKVRILVADDDDVQRKILNNLLKKFHYNVTLVPNGEIAWEYINKGQQKYDLVLTDVMMPHITGFDLLQRINDHPVHRHIPVILMSGTAVDYKYANDTIKIGGQDFLTKPIAKELLKKKIDTVLQSIWQRRKEEEYKATLAQEREKGNKLAKEMELKEHEIEELTKKVSKMSSISKEAMESPLVSVTRNIEELLKQSSWSHYESEIKEKLSSILKELGSSNIYRPSFEKLIKNDSVDPVTKSFLVSEFSSTTSRRNSIPTFPQTTYNRDTKEVIKGWEFDVFKYSEDDLMPLLVDMFENFQLPEIFKIPIEKLQRFIMTVNALYRKNNRYHNFTHAFDVTQTVYTFLTSFNAAQYLTHLDIFALLISCMCHDLNHPGFNNTFQVNAQTELSLEYNDISVLENHHAMLTFKILRNSECNILEGLNEDQYKELRRSVVQLILATDMQNHFEHTNKFQHHLNNLPFDRNKKEDRQMILNFLIKCGDISNIARPWHLNFEWSLRVSDEFFQQSHYETICGYPVTPFMDKTKTTRARIAADFIDFVASPLFQSMAKFLKESQFLLKVISKNRENWQAYMELQKEGKCNDDDLQFMEDPTILVKSKLPKIDEEENRDKVSSSSSSSTAPLTSTSSSNNETSSS", "length": 793, "molWeight": 91176, "crc64": "6E065A96620F8C27", "md5": "2F806DA375FFC6C9066DBE5883759BC3"}}
{"primaryAccession": "Q24142", "text": "This is Nuclear hormone receptor HR78 protein, from Fruit fly, contains 601 amino acids, has 2 NR C4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [52, 72], "description": "NR C4-type", "keyword_description": "Zinc finger", "textural_description": "NR C4-type Zinc finger"}, {"location": [88, 107], "description": "NR C4-type", "keyword_description": "Zinc finger", "textural_description": "NR C4-type Zinc finger"}], "meta_data": {"primaryAccession": "Q24142", "organism_name": "Fruit fly", "protein_name": "Nuclear hormone receptor HR78", "length": 601, "firstPublicDate": "1997-11-01", "FUNCTION": "Binds to direct repeats of the sequence 5'-AGGTCA-3', Inhibits the ecdysone response, Plays an essential role in regulating molting of the tracheal cuticle during larval development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the nuclear hormone receptor family, NR2 subfamily", "domain_description": {"NR C4-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDGVKVETFIKSEENRAMPLIGGGSASGGTPLPGGGVGMGAGASATLSVELCLVCGDRASGRHYGAISCEGCKGFFKRSIRKQLGYQCRGAMNCEVTKHHRNRCQFCRLQKCLASGMRSDSVQHERKPIVDRKEGIIAAAGSSSTSGGGNGSSTYLSGKSGYQQGRGKGHSVKAESAATPPVHSAPATAFNLNENIFPMGLNFAELTQTLMFATQQQQQQQQQHQQSGSYSPDIPKADPEDDEDDSMDNSSTLCLQLLANSASNNNSQHLNFNAGEVPTALPTTSTMGLIQSSLDMRVIHKGLQILQPIQNQLERNGNLSVKPECDSEAEDSGTEDAVDAELEHMELDFECGGNRSGGSDFAINEAVFEQDLLTDVQCAFHVQPPTLVHSYLNIHYVCETGSRIIFLTIHTLRKVPVFEQLEAHTQVKLLRGVWPALMAIALAQCQGQLSVPTIIGQFIQSTRQLADIDKIEPLKISKMANLTRTLHDFVQELQSLDVTDMEFGLLRLILLFNPTLLQQRKERSLRGYVRRVQLYALSSLRRQGGIGGGEERFNVLVARLLPLSSLDAEAMEELFFANLVGQMQMDALIPFILMTSNTSGL", "length": 601, "molWeight": 65393, "crc64": "82C48A2885EEAA0C", "md5": "AD1438DFA48AE0F44560FDB147887A16"}}
{"primaryAccession": "Q27249", "text": "This is Tropomyosin isoforms c/e protein, from Caenorhabditis elegans, contains 256 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q27249", "organism_name": "Caenorhabditis elegans", "protein_name": "Tropomyosin isoforms c/e", "length": 256, "firstPublicDate": "2004-02-16", "FUNCTION": "Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction, Involved in muscle actin filament organization and muscle arm extension and morphology, Also has a role in male mating behavior by regulating the copulatory spicules, Binds to F-actin", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the tropomyosin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSKVNKEGAQQTSLLDVLKKKMRQAREEAEAAKDEADEVKRQLEEERKKREDAEAEVAALNRRIVLVEEDLERTEDRLKTATSKLEQATKAADEADRARKSMETRSQQDEERANFLETQVDEAKVIAEDADRKYEEVARKLAMVEADLERAEERAEAGENKIVELEEELRVVGNNLKSLEVSEEKALQREDSYEEQIRTVSSRLKEAETRAEFAERSVQKLQKEVDRLEDELLLEKERVRNLTEEIEQTVQEIQGS", "length": 256, "molWeight": 29632, "crc64": "84144312558238C5", "md5": "FCC70D7D7BF38D850CB8F1D2C8A85634"}}
{"primaryAccession": "Q27511", "text": "This is Histone H2A.V protein, from Caenorhabditis elegans, contains 140 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q27511", "organism_name": "Caenorhabditis elegans", "protein_name": "Histone H2A.V", "length": 140, "firstPublicDate": "2006-05-30", "FUNCTION": "Variant histone H2A which replaces conventional H2A in a subset of nucleosomes, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity), Required to maintain non-distal tip cell (DTC) fate of somatic gonadal cells through the repression of transcription factor ceh-22 (PubMed:24346701)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGGKGKAGKDSGKSKSKVVSRSARAGLQFPVGRIHRFLKQRTTSSGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLHLAIRGDEELDTLIKATIAGGGVIPHIHRYLMNKKGAPVPGKPGAPGQGPQ", "length": 140, "molWeight": 14669, "crc64": "3E3435A8FAE6D821", "md5": "73E91C4B0EC39E1C49FF83C91E4409B4"}}
{"primaryAccession": "Q27908", "text": "This is Nacrein protein, from Akoya pearl oyster, contains 447 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q27908", "organism_name": "Akoya pearl oyster", "protein_name": "Nacrein", "length": 447, "firstPublicDate": "2009-07-28", "FUNCTION": "Acts as a negative regulator for calcification in the shells of mollusks, May function both as a calcium concentrator and as a carbonic anhydrase required for production of carbonate ions, which are assembled to CaCO(3) at mineralization sites, Is important for shell formation in both the calcitic prismatic layer and the aragonitic nacreous layer", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the alpha-carbonic anhydrase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MYLHLTALCVVIPLCYGASMFKHDHYMDNGVRYPNGDGICKQLNETKCDAGFSYDRSICEGPHYWHTISKCFIACGIGQRQSPINIVSYDAKFRQRLPKLKFKPHMEKLKTEVTNHQNRAPEFEPEDGENLYVKLNNLVDGHYKFHNLHVHNGRTRRKGSEHSVNGRFTPMEAHLVFHHDDQTHFEPTRTKLGGAFPGHNDFVVVGVFLEVGDDGFGDEPDDEECKHILKGHHPDNNENGNGDNGNNGYNGDNGNNGDNGNNSYNGDNGNNGVNGNNGYNGDNGNNGDNGNNGYNGDNGNNGDNGNNGENGNNGENGNNGENGHKHGCRVKKAKHLSRILECAYRNDKVREFKKVGEEEGLDVHLTPEMALPPLKYRHYYTYEGSLTTPPCTESVLWVVQKCHVQVSRRVLHALRNVEGYKDGTTLRKYGTRRPTQKNKVTVYKSFK", "length": 447, "molWeight": 50114, "crc64": "334191045E91AB8C", "md5": "B8CB205DB2F6EF311DE985E6448DDBB3"}}
{"primaryAccession": "Q2M2Z5", "text": "This is Centrosomal protein kizuna protein, from Human, contains 673 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q2M2Z5", "organism_name": "Human", "protein_name": "Centrosomal protein kizuna", "length": 673, "firstPublicDate": "2007-09-11", "FUNCTION": "Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation, Required for stabilizing the expanded pericentriolar material around the centriole", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the kizuna family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSRTLASAVPLSSPDYYERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD", "length": 673, "molWeight": 75111, "crc64": "3B6BDE3A479B5933", "md5": "9C8F126A525E06A13300CADB4C7E2E4C"}}
{"primaryAccession": "Q2TAA5", "text": "This is GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase protein, from Human, contains 492 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q2TAA5", "organism_name": "Human", "protein_name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "length": 492, "firstPublicDate": "2007-07-24", "FUNCTION": "Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum, Catalyzes the addition of the 4th and 5th mannose residues to the dolichol-linked oligosaccharide chain", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyltransferase group 1 family, Glycosyltransferase 4 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAGERSWCLCKLLRFFYSLFFPGLIVCGTLCVCLVIVLWGIRLLLQRKKKLVSTSKNGKNQMVIAFFHPYCNAGGGGERVLWCALRALQKKYPEAVYVVYTGDVNVNGQQILEGAFRRFNIRLIHPVQFVFLRKRYLVEDSLYPHFTLLGQSLGSIFLGWEALMQCVPDVYIDSMGYAFTLPLFKYIGGCQVGSYVHYPTISTDMLSVVKNQNIGFNNAAFITRNPFLSKVKLIYYYLFAFIYGLVGSCSDVVMVNSSWTLNHILSLWKVGNCTNIVYPPCDVQTFLDIPLHEKKMTPGHLLVSVGQFRPEKNHPLQIRAFAKLLNKKMVESPPSLKLVLIGGCRNKDDELRVNQLRRLSEDLGVQEYVEFKINIPFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVVPHEGDITGFLAESEEDYAETIAHILSMSAEKRLQIRKSARASVSRFSDQEFEVTFLSSVEKLFK", "length": 492, "molWeight": 55651, "crc64": "1B3B0789030777FC", "md5": "096BE5A6144A32B740D5AA0D23125F39"}}
{"primaryAccession": "Q2U1F3", "text": "This is Leucine aminopeptidase A protein, from Yellow koji mold, contains 377 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q2U1F3", "organism_name": "Yellow koji mold", "protein_name": "Leucine aminopeptidase A", "length": 377, "firstPublicDate": "2011-09-21", "FUNCTION": "Extracellular aminopeptidase that allows assimilation of proteinaceous substrates", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M28 family, M28E subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRFLPCIATLAATASALAIGDHVRSDDQYVLELAPGQTKVVTEAEKWALRAEGKRFFDITERASSLELASNKKQKLAVTYPDSVQHNETVQNLIKSLDKKNFETVLQPFSEFHNRYYKSDNGKKSSEWLQGKIQEIISASGAKGVTVEPFKHSFPQSSLIAKIPGKSDKTIVLGAHQDSINLDSPSEGRAPGADDDGSGVVTILEAFRVLLTDEKVAAGEAPNTVEFHFYAGEEGGLLGSQDIFEQYSQKSRDVKAMLQQDMTGYTKGTTDAGKPESIGIITDNVDENLTKFLKVIVDAYCTIPTVDSKCGYGCSDHASATKYGYPAAFAFESAFGDDSPYIHSADDTIETVNFDHVLQHGRLTLGFAYELAFADSL", "length": 377, "molWeight": 41105, "crc64": "FC46EBEF3195CA76", "md5": "2FB8A8EA8F9AD1F73FBE86998E944122"}}
{"primaryAccession": "Q2ULM2", "text": "This is probable leucine aminopeptidase 2 protein, from Yellow koji mold, contains 496 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q2ULM2", "organism_name": "Yellow koji mold", "protein_name": "probable leucine aminopeptidase 2", "length": 496, "firstPublicDate": "2010-10-05", "FUNCTION": "Extracellular aminopeptidase that releases a wide variety of amino acids from natural peptides", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M28 family, M28A subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRSLLWASLLSGVLAGRALVSPDEFPEDIQLEDLLEGSQQLEDFAYAYPERNRVFGGKAHDDTVNYLYEELKKTGYYDVYKQPQVHLWSNADQTLKVGDEEIEAKTMTYSPSVEVTADVAVVKNLGCSEADYPSDVEGKVALIKRGECPFGDKSVLAAKAKAAASIVYNNVAGSMAGTLGAAQSDKGPYSAIVGISLEDGQKLIKLAEAGSVSVDLWVDSKQENRTTYNVVAQTKGGDPNNVVALGGHTDSVEAGPGINDDGSGIISNLVIAKALTQYSVKNAVRFLFWTAEEFGLLGSNYYVSHLNATELNKIRLYLNFDMIASPNYALMIYDGDGSAFNQSGPAGSAQIEKLFEDYYDSIDLPHIPTQFDGRSDYEAFILNGIPSGGLFTGAEGIMSEENASRWGGQAGVAYDANYHAAGDNMTNLNHEAFLINSKATAFAVATYANDLSSIPKRNTTSSLHRRARTMRPFGKRAPKTHAHVSGSGCWHSQVEA", "length": 496, "molWeight": 53557, "crc64": "266767E9527E399E", "md5": "73E9FA751A9D9539D0F25B6985B168D3"}}
{"primaryAccession": "Q38819", "text": "This is Cyclin-A2-3 protein, from Mouse-ear cress, contains 450 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q38819", "organism_name": "Mouse-ear cress", "protein_name": "Cyclin-A2-3", "length": 450, "firstPublicDate": "2007-05-15", "FUNCTION": "Negatively regulates endocycles and acts as a regulator of ploidy levels in endoreduplication (PubMed:16415207), Promotes divisions in the guard cells (GCs) after the guard mother cells (GMC) symmetric division (PubMed:24687979)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the cyclin family, Cyclin AB subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGKENAVSRPFTRSLASALRASEVTSTTQNQQRVNTKRPALEDTRATGPNKRKKRAVLGEITNVNSNTAILEAKNSKQIKKGRGHGLASTSQLATSVTSEVTDLQSRTDAKVEVASNTAGNLSVSKGTDNTADNCIEIWNSRLPPRPLGRSASTAEKSAVIGSSTVPDIPKFVDIDSDDKDPLLCCLYAPEIHYNLRVSELKRRPLPDFMERIQKDVTQSMRGILVDWLVEVSEEYTLASDTLYLTVYLIDWFLHGNYVQRQQLQLLGITCMLIASKYEEISAPRIEEFCFITDNTYTRDQVLEMENQVLKHFSFQIYTPTPKTFLRRFLRAAQASRLSPSLEVEFLASYLTELTLIDYHFLKFLPSVVAASAVFLAKWTMDQSNHPWNPTLEHYTTYKASDLKASVHALQDLQLNTKGCPLSAIRMKYRQEKYKSVAVLTSPKLLDTLF", "length": 450, "molWeight": 50642, "crc64": "8EF3B638843CD478", "md5": "15998B19F0F69885DCBA24C073C16588"}}
{"primaryAccession": "Q38898", "text": "This is Potassium channel AKT2/3 protein, from Mouse-ear cress, contains 802 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q38898", "organism_name": "Mouse-ear cress", "protein_name": "Potassium channel AKT2/3", "length": 802, "firstPublicDate": "2004-03-01", "FUNCTION": "Highly selective and weak inward-rectifying potassium channel, Plays a role in both loading and unloading potassium into/from the phloem sap, Seems to control sugar loading into phloem via a voltage-dependent process, Blocked by physiological concentrations of external calcium and by external acidification, May interact with the cytoskeleton or with regulatory proteins, Dephosphorylation by PP2CA not only leads to the inhibition of potassium currents but also to an increase of the voltage-dependence of the channel, Regulated by the CBL4/CIPK6 calcium sensor/protein kinase complex via a kinase interaction-dependent but phosphorylation-independent translocation of the channel to the plasma membrane", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the potassium channel family, Plant (TC 1,A,1,4) subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDLKYSASHCNLSSDMKLRRFHQHRGKGREEEYDASSLSLNNLSKLILPPLGVASYNQNHIRSSGWIISPMDSRYRCWEFYMVLLVAYSAWVYPFEVAFLNSSPKRNLCIADNIVDLFFAVDIVLTFFVAYIDERTQLLVREPKQIAVRYLSTWFLMDVASTIPFDAIGYLITGTSTLNITCNLLGLLRFWRLRRVKHLFTRLEKDIRYSYFWIRCFRLLSVTLFLVHCAGCSYYLIADRYPHQGKTWTDAIPNFTETSLSIRYIAAIYWSITTMTTVGYGDLHASNTIEMVFITVYMLFNLGLTAYLIGNMTNLVVEGTRRTMEFRNSIEAASNFVNRNRLPPRLKDQILAYMCLRFKAESLNQQHLIDQLPKSIYKSICQHLFLPSVEKVYLFKGVSREILLLLVSKMKAEYIPPREDVIMQNEAPDDVYIIVSGEVEIIDSEMERESVLGTLRCGDIFGEVGALCCRPQSYTFQTKSLSQLLRLKTSFLIETMQIKQQDNATMLKNFLQHHKKLSNLDIGDLKAQQNGENTDVVPPNIASNLIAVVTTGNAALLDELLKAKLSPDITDSKGKTPLHVAASRGYEDCVLVLLKHGCNIHIRDVNGNSALWEAIISKHYEIFRILYHFAAISDPHIAGDLLCEAAKQNNVEVMKALLKQGLNVDTEDHHGVTALQVAMAEDQMDMVNLLATNGADVVCVNTHNEFTPLEKLRVVEEEEEEERGRVSIYRGHPLERRERSCNEAGKLILLPPSLDDLKKIAGEKFGFDGSETMVTNEDGAEIDSIEVIRDNDKLYFVVNKII", "length": 802, "molWeight": 91308, "crc64": "6F138F9149ED3CD7", "md5": "8F54D95486082FCCF02D29218576543F"}}
{"primaryAccession": "Q38998", "text": "This is Potassium channel AKT1 protein, from Mouse-ear cress, contains 857 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q38998", "organism_name": "Mouse-ear cress", "protein_name": "Potassium channel AKT1", "length": 857, "firstPublicDate": "2004-03-01", "FUNCTION": "Highly selective inward-rectifying potassium channel that mediate potassium uptake by plant roots in response to low K(+) conditions, by a calcium-, CBL-, and CIPK-dependent pathway, Positively regulated by phosphorylation by CIPK23, Negatively regulated by a kinase-independent regulatory mechanism involving a competing direct binding of CBL10, Involved in the stomatal regulation by monitoring the turgor pressure in guard cells, Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by hyperpolarization, May interact with the cytoskeleton or with regulatory proteins (PubMed:12678562, PubMed:16814720, PubMed:16895985, PubMed:17898163, PubMed:9572739), Is essential with POT5/HAK5 for high-affinity potassium uptake in roots during seedling establishment and postgermination growth under low potassium conditions (PubMed:20413648)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the potassium channel family, Plant (TC 1,A,1,4) subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRGGALLCGQVQDEIEQLSRESSHFSLSTGILPSLGARSNRRVKLRRFVVSPYDHKYRIWEAFLVVLVVYTAWVSPFEFGFLRKPRPPLSITDNIVNAFFAIDIIMTFFVGYLDKSTYLIVDDRKQIAFKYLRSWFLLDLVSTIPSEAAMRISSQSYGLFNMLRLWRLRRVGALFARLEKDRNFNYFWVRCAKLVCVTLFAVHCAACFYYLIAARNSNPAKTWIGANVANFLEESLWMRYVTSMYWSITTLTTVGYGDLHPVNTKEMIFDIFYMLFNLGLTAYLIGNMTNLVVHGTSRTRNFRDTIQAASNFAHRNHLPPRLQDQMLAHLCLKYRTDSEGLQQQETLDALPKAIRSSISHFLFYSLMDKVYLFRGVSNDLLFQLVSEMKAEYFPPKEDVILQNEAPTDFYILVNGTADLVDVDTGTESIVREVKAGDIIGEIGVLCYRPQLFTVRTKRLCQLLRMNRTTFLNIIQANVGDGTIIMNNLLQHLKEMNDPVMTNVLLEIENMLARGKMDLPLNLCFAAIREDDLLLHQLLKRGLDPNESDNNGRTPLHIAASKGTLNCVLLLLEYHADPNCRDAEGSVPLWEAMVEGHEKVVKVLLEHGSTIDAGDVGHFACTAAEQGNLKLLKEIVLHGGDVTRPRATGTSALHTAVCEENIEMVKYLLEQGADVNKQDMHGWTPRDLAEQQGHEDIKALFREKLHERRVHIETSSSVPILKTGIRFLGRFTSEPNIRPASREVSFRIRETRARRKTNNFDNSLFGILANQSVPKNGLATVDEGRTGNPVRVTISCAEKDDIAGKLVLLPGSFKELLELGSNKFGIVATKVMNKDNNAEIDDVDVIRDGDHLIFATDS", "length": 857, "molWeight": 96990, "crc64": "28E1622BA3505F4C", "md5": "CAA803A49E8812B1CBE32315BB0157E5"}}
{"primaryAccession": "Q39044", "text": "This is Vacuolar-processing enzyme beta-isozyme protein, from Mouse-ear cress, contains 486 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q39044", "organism_name": "Mouse-ear cress", "protein_name": "Vacuolar-processing enzyme beta-isozyme", "length": 486, "firstPublicDate": "2002-07-11", "FUNCTION": "Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms (By similarity), Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds (PubMed:12417707, PubMed:14688293)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the peptidase C13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAKSCYFRPALLLLLVLLVHAESRGRFEPKILMPTEEANPADQDEDGVGTRWAVLVAGSSGYGNYRHQADVCHAYQILRKGGLKEENIVVLMYDDIANHPLNPRPGTLINHPDGDDVYAGVPKDYTGSSVTAANFYAVLLGDQKAVKGGSGKVIASKPNDHIFVYYADHGGPGVLGMPNTPHIYAADFIETLKKKHASGTYKEMVIYVEACESGSIFEGIMPKDLNIYVTTASNAQESSYGTYCPGMNPSPPSEYITCLGDLYSVAWMEDSETHNLKKETIKQQYHTVKMRTSNYNTYSGGSHVMEYGNNSIKSEKLYLYQGFDPATVNLPLNELPVKSKIGVVNQRDADLLFLWHMYRTSEDGSRKKDDTLKELTETTRHRKHLDASVELIATILFGPTMNVLNLVREPGLPLVDDWECLKSMVRVFEEHCGSLTQYGMKHMRAFANVCNNGVSKELMEEASTAACGGYSEARYTVHPSILGYSA", "length": 486, "molWeight": 53828, "crc64": "8B3EFD53CDAEC9C3", "md5": "A7BAC138E9F5936E6DD28755C6B8E523"}}
{"primaryAccession": "Q39119", "text": "This is Vacuolar-processing enzyme gamma-isozyme protein, from Mouse-ear cress, contains 494 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q39119", "organism_name": "Mouse-ear cress", "protein_name": "Vacuolar-processing enzyme gamma-isozyme", "length": 494, "firstPublicDate": "2001-07-11", "FUNCTION": "Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms (PubMed:10417725), Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds (PubMed:14688293)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the peptidase C13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATTMTRVSVGVVLFVLLVSLVAVSAARSGPDDVIKLPSQASRFFRPAENDDDSNSGTRWAVLVAGSSGYWNYRHQADICHAYQLLRKGGLKEENIVVFMYDDIANNYENPRPGTIINSPHGKDVYQGVPKDYTGDDVNVDNLFAVILGDKTAVKGGSGKVVDSGPNDHIFIFYSDHGGPGVLGMPTSPYLYANDLNDVLKKKHALGTYKSLVFYLEACESGSIFEGLLPEGLNIYATTASNAEESSWGTYCPGEEPSPPPEYETCLGDLYSVAWMEDSGMHNLQTETLHQQYELVKRRTAPVGYSYGSHVMQYGDVGISKDNLDLYMGTNPANDNFTFADANSLKPPSRVTNQRDADLVHFWEKYRKAPEGSARKTEAQKQVLEAMSHRLHIDNSVILVGKILFGISRGPEVLNKVRSAGQPLVDDWNCLKNQVRAFERHCGSLSQYGIKHMRSFANICNAGIQMEQMEEAASQACTTLPTGPWSSLNRGFSA", "length": 494, "molWeight": 54336, "crc64": "9C8C47E644490984", "md5": "1A12F5120C4875D97139E3C90D6E7B5E"}}
{"primaryAccession": "Q39238", "text": "This is Serine/threonine-protein kinase TOUSLED protein, from Mouse-ear cress, contains 688 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q39238", "organism_name": "Mouse-ear cress", "protein_name": "Serine/threonine-protein kinase TOUSLED", "length": 688, "firstPublicDate": "2007-01-09", "FUNCTION": "Required for correct initiation of floral organ primordia and for proper development of organ primordia, Phosphorylates in vitro ASF1B/SGA1, the C-terminal part of TKI1 and histone H3", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSDDMVLHFSSNSSNQSDHSLPDKIAKLEARLTGKTPSSAKPPQQQQQQQQQVSLWSSASAAVKVVTSTPPGLSETSISDSDDENTGDFLIRANTKKRQKVQESNNFSVVDHVEPQEAAYDGRKNDAESKTGLDVSKKKQGRGRASSTGRGRGSKTNNDVTKSQFVVAPVSAASQLDASDQKDFRPDGQLRNGECSLQDEDLKSLRAKIAMLEEELRKSRQDSSEYHHLVRNLENEVKDLKDQEQQGKQKTTKVISDLLISVSKTERQEARTKVRNESLRLGSVGVLRTGTIIAETWEDGQMLKDLNAQLRQLLETKEAIERQRKLLKKRQNGDKNDGTDTESGAQEEDIIPDEVYKSRLTSIKREEEAVLRERERYTLEKGLLMREMKRIRDEDGSRFNHFPVLNSRYALLNLLGKGGFSEVYKAYDLVDHRYVACKLHGLNAQWSEEKKQSYIRHANRECEIHKSLVHHHIVRLWDKFHIDMHTFCTVLEYCSGKDLDAVLKATSNLPEKEARIIIVQIVQGLVYLNKKSQKIIHYDLKPGNVLFDEFGVAKVTDFGLSKIVEDNVGSQGMELTSQGAGTYWYLPPECFELNKTPMISSKVDVWSVGVLFYQMLFGKRPFGHDQSQERILREDTIIKAKKVEFPVTRPAISNEAKDLIRRCLTYNQEDRPDVLTMAQDPYLAYSKK", "length": 688, "molWeight": 78149, "crc64": "2B14F0E677D78C9B", "md5": "1F171A557F40CE621EB4D30A250E61CF"}}
{"primaryAccession": "Q39250", "text": "This is Actin-depolymerizing factor 1 protein, from Mouse-ear cress, contains 139 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q39250", "organism_name": "Mouse-ear cress", "protein_name": "Actin-depolymerizing factor 1", "length": 139, "firstPublicDate": "2001-11-02", "FUNCTION": "Actin-depolymerizing protein, Stimulates F-actin depolymerization, Involved in plant development, cell organ expansion and flowering by controlling breakdown of thick actin cables (PubMed:11402164), Severs actin filaments or bundles and promotes actin cytoskeleton disassembly (PubMed:21570971), Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin (PubMed:17538023)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the actin-binding proteins ADF family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MANAASGMAVHDDCKLRFLELKAKRTHRFIVYKIEEKQKQVVVEKVGQPIQTYEEFAACLPADECRYAIYDFDFVTAENCQKSKIFFIAWCPDIAKVRSKMIYASSKDRFKRELDGIQVELQATDPTEMDLDVFRSRAN", "length": 139, "molWeight": 16113, "crc64": "E9429E0FE23A944F", "md5": "6514238DFF6D76B84FE80DBC540B796D"}}
{"primaryAccession": "Q3E754", "text": "This is Small ribosomal subunit protein eS21B protein, from Baker's yeast, contains 87 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3E754", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS21B", "length": 87, "firstPublicDate": "2005-12-20", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102), eS21 is required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits, Has a physiological role leading to 18S rRNA stability (PubMed:14627813)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS21 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MENDKGQLVELYVPRKCSATNRIIKADDHASVQINVAKVDEEGRAIPGEYITYALSGYVRSRGESDDSLNRLAQNDGLLKNVWSYSR", "length": 87, "molWeight": 9760, "crc64": "52E1C247575A7410", "md5": "E0A0345E837FC30EA6F5E993F21558F2"}}
{"primaryAccession": "Q3E792", "text": "This is Small ribosomal subunit protein eS25A protein, from Baker's yeast, contains 108 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3E792", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS25A", "length": 108, "firstPublicDate": "1988-04-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS25 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPPKQQLSKAAKAAAALAGGKKSKKKWSKKSMKDRAQHAVILDQEKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYTRATASE", "length": 108, "molWeight": 12039, "crc64": "C52D0328DEA125B5", "md5": "9DB1F09D860E4597977C95AB9586C433"}}
{"primaryAccession": "Q3E7B6", "text": "This is V-type proton ATPase subunit e protein, from Baker's yeast, contains 73 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3E7B6", "organism_name": "Baker's yeast", "protein_name": "V-type proton ATPase subunit e", "length": 73, "firstPublicDate": "2006-01-10", "FUNCTION": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:14594803), V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:14594803)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the V-ATPase e1/e2 subunit family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSFYTVVGVFIVVSAMSVLFWIMAPKNNQAVWRSTVILTLAMMFLMWAITFLCQLHPLVAPRRSDLRPEFAE", "length": 73, "molWeight": 8381, "crc64": "B1440E10D0D34818", "md5": "9A818F086C865E4B065D0EC11A69074F"}}
{"primaryAccession": "Q3E7X9", "text": "This is Small ribosomal subunit protein eS28A protein, from Baker's yeast, contains 67 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3E7X9", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS28A", "length": 67, "firstPublicDate": "1986-07-21", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS28 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDNKTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR", "length": 67, "molWeight": 7592, "crc64": "BA145824DEE8A641", "md5": "CAE424C69EDE593F6A29DC2D91A241FD"}}
{"primaryAccession": "Q3EBR6", "text": "This is Phospholipase A1-Igamma2, chloroplastic protein, from Mouse-ear cress, contains 529 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3EBR6", "organism_name": "Mouse-ear cress", "protein_name": "Phospholipase A1-Igamma2, chloroplastic", "length": 529, "firstPublicDate": "2010-10-05", "FUNCTION": "Acylhydrolase with broad specificity (PubMed:19527719), Catalyzes the hydrolysis of phosphatidylcholine at the sn-1 position (PubMed:19527719), Possesses moderate activity toward phosphatidylcholine (PC), monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG) and triacylglycerol (TAG) (PubMed:19527719)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAIPSHNNLLTINHKNSITGSSSLNTNFSEINFPAKFRVATRALSRTDESSLSAVISRLERERRERQGLLIEEAEGAGELWMTAEDIRRRDKKTEEERRLRDTWRKIQGEDDWAGLMDPMDPILRSELIRYGEMAQACYDAFDFDPASKYCGTSRFTRLEFFDSLGMIDSGYEVARYLYATSNINLPNFFSKSRWSKVWSKNANWMGYVAVSDDETSRNRLGRRDIAIAWRGTVTKLEWIADLKDYLKPVTENKIRCPDPAVKVESGFLDLYTDKDTTCKFARFSAREQILTEVKRLVEEHGDDDDSDLSITVTGHSLGGALAILSAYDIAEMRLNRSKKGKVIPVTVLTYGGPRVGNVRFRERMEELGVKVMRVVNVHDVVPKSPGLFLNESRPHALMKIAEGLPWCYSHVGEELALDHQNSPFLKPSVDVSTAHNLEAMLHLLDGYHGKGERFVLSSGRDHALVNKASDFLKEHLQIPPFWRQDANKGMVRNSEGRWIQAERLRFEDHHSPDIHHHLSQLRLDHPC", "length": 529, "molWeight": 60402, "crc64": "2F02B3C51953B020", "md5": "B97FA75131C3851DF859B0F06B2D702B"}}
{"primaryAccession": "Q3EDG5", "text": "This is Protein-tyrosine sulfotransferase protein, from Mouse-ear cress, contains 500 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3EDG5", "organism_name": "Mouse-ear cress", "protein_name": "Protein-tyrosine sulfotransferase", "length": 500, "firstPublicDate": "2009-10-13", "FUNCTION": "Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQMNSVWKLSLGLLLLSSVIGSFAELDFGHCETLVKKWADSSSSREEHVNKDKRSLKDLLFFLHVPRTGGRTYFHCFLRKLYDSSEECPRSYDKLHFNPRKEKCKLLATHDDYSLMAKLPRERTSVMTIVRDPIARVLSTYEFSVEVAARFLVHPNLTSASRMSSRIRKSNVISTLDIWPWKYLVPWMREDLFARRDARKLKEVVIIEDDNPYDMEEMLMPLHKYLDAPTAHDIIHNGATFQIAGLTNNSHLSEAHEVRHCVQKFKSLGESVLQVAKRRLDSMLYVGLTEEHRESASLFANVVGSQVLSQVVPSNATAKIKALKSEASVTISETGSDKSNIQNGTSEVTLNKAEAKSGNMTVKTLMEVYEGCITHLRKSQGTRRVNSLKRITPANFTRGTRTRVPKEVIQQIKSLNNLDVELYKYAKVIFAKEHELVSNKLISSSKRSIVDLPSELKSVLGEMGEEKLWKFVPVALMLLLIVLFFLFVNAKRRRTSKVKI", "length": 500, "molWeight": 56989, "crc64": "06B1B2EBE2F07CCC", "md5": "5B10204867CE511F2BD8F31D915FED39"}}
{"primaryAccession": "Q3MIR4", "text": "This is Cell cycle control protein 50B protein, from Human, contains 351 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3MIR4", "organism_name": "Human", "protein_name": "Cell cycle control protein 50B", "length": 351, "firstPublicDate": "2006-06-27", "FUNCTION": "Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids, Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules, The beta subunit may assist in binding of the phospholipid substrate (Probable), Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the CDC50/LEM3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTWSATARGAHQPDNTAFTQQRLPAWQPLLSASIALPLFFCAGLAFIGLGLGLYYSSNGIKELEYDYTGDPGTGNCSVCAAAGQGRALPPPCSCAWYFSLPELFQGPVYLYYELTNFYQNNRRYGVSRDDAQLSGLPSALRHPVNECAPYQRSAAGLPIAPCGAIANSLFNDSFSLWHQRQPGGPYVEVPLDRSGIAWWTDYHVKFRNPPLVNGSLALAFQGTAPPPNWRRPVYELSPDPNNTGFINQDFVVWMRTAALPTFRKLYARIRQGNYSAGLPRGAYRVNITYNYPVRAFGGHKLLIFSSISWMGGKNPFLGIAYLVVGSLCILTGFVMLVVYIRYQDQDDDDEE", "length": 351, "molWeight": 38941, "crc64": "B68C91A784E33A44", "md5": "9D19265D04AC364F0B4361301375D9A5"}}
{"primaryAccession": "Q3SY69", "text": "This is Mitochondrial 10-formyltetrahydrofolate dehydrogenase protein, from Human, contains 923 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3SY69", "organism_name": "Human", "protein_name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "length": 923, "firstPublicDate": "2008-01-15", "FUNCTION": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "In the C-terminal section; belongs to the aldehyde dehydrogenase family, ALDH1L subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRRGSQALRRFSTGRVYFKNKLKLALIGQSLFGQEVYSHLRKEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEINGQMVTFYGSTLLNSSVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFEDGKMIPASQYFSTGETSVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKCGGLQLQNEDVYMATKFEGFIQKVVRKLRGEDQEVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY", "length": 923, "molWeight": 101746, "crc64": "C5DD74506F08AAFE", "md5": "2758610B62F8C9CEF0A2715CAF2F775F"}}
{"primaryAccession": "Q3TTA7", "text": "This is E3 ubiquitin-protein ligase CBL-B protein, from Mouse, contains 982 amino acids, has 1 RING-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [373, 412], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q3TTA7", "organism_name": "Mouse", "protein_name": "E3 ubiquitin-protein ligase CBL-B", "length": 982, "firstPublicDate": "2006-02-07", "FUNCTION": "E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome, Negatively regulates TCR (T-cell receptor), BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways, In naive T-cells, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production, Also acts by promoting PIK3R1/p85 ubiquitination, which impairs its recruitment to the TCR and subsequent activation, In activated T-cells, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy, In B-cells, acts by ubiquitinating SYK and promoting its proteasomal degradation, Slightly promotes SRC ubiquitination, May be involved in EGFR ubiquitination and internalization, May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3, In association with CBL, required for proper feedback inhibition of ciliary platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway via ubiquitination and internalization of PDGFRA (PubMed:29237719)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPFDPRDEGSRCCSIIDPFSIPMLDLDDDDDREESLMMNRLASVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPERPPPIPPDNRLSRHFHHGESVPSRDQPMPLEAWCPRDAFGTNQVMGCRILGDGSPKPGVTANSSLNGRHSRMGSEQVLMRKHRRHDLPSEGAKVFSNGHLATEEYDVPPRLSPPPPVTTLLPSIKCTGPLANCLSEKTRDTVEDDDDEYKIPSSHPVSLNSQPSHCHNVKAPVRSCDNGHCILNGTHGAPSEMKKSNIPDLGIYLKGGGSDSASDPVPLPPARPPPRDSPKHGSSVNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFFDPTSGQVPLPPARRAAGDSGKANRASQDYDQLPSSSDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNVEVARSILREFAFPPPVSPRLNL", "length": 982, "molWeight": 109092, "crc64": "14B55C4106F84A86", "md5": "04E6C46F9EEBE871FD290F4D700CA46B"}}
{"primaryAccession": "Q3TYA6", "text": "This is M-phase phosphoprotein 8 protein, from Mouse, contains 858 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3TYA6", "organism_name": "Mouse", "protein_name": "M-phase phosphoprotein 8", "length": 858, "firstPublicDate": "2012-03-21", "FUNCTION": "Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression, Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2, Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene, Mediates down-regulation of CDH1 expression, Also represses L1 retrotransposons in collaboration with MORC2 and, probably, SETDB1, the silencing is dependent of repressive epigenetic modifications, such as H3K9me3 mark, Silencing events often occur within introns of transcriptionally active genes, and lead to the down-regulation of host gene expression, The HUSH complex is also involved in the silencing of unintegrated retroviral DNA by being recruited by ZNF638: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAAAEEGMSAAALVMSVPDSIGRSPESEGVGAGDEEKDAATKGTVAVGDSEEDGEDVFEVERILDMKCEGGKNLYKVRWKGYTSEDDTWEPEVHLEDCKEVLLEFRKKLAENKAKAVRKDIQRLSLNNDIFEADSDSDQQSDTKEDISPRKKKKKIKCKEETSPEDLRKKRTKMGKLKDKFKTELESTSEIIGFDVKTKKRIWEVKEELKDSKKPKKDEIKETKELKKANKRAEVRDLKIKIREDVKENRKTKKERYIESPLESESPNDSLILEDDSEDFISDNREENQNVRSVRDKTAQETVQEGIFEKHLDDLISIEEDAGTRVRRKKTKPRKFEEPKEIKKLESTNAFLERRAIPKKQRNQDKGISNLELNKLPSPVFAQTLKSSRLSGEEKSLKSPDLAEEEKEKKNEPKGKYQKRYDLDKEEKARKEPKVLKSFKEIRNAFDLFKKTTEEKNDVLENNSKREEISLDSKIMNDNKTKDKCSLKEKRNTRDETDTWAYIAAEGDQEVSDSVCQTDETSDGRQPVLSLGMDLQLEWMKLEDFQKHLDGEDEPFITTNRIPNNLLRDAVKNGDYIAVKVALNSNEEYNLDQEDSTGMTLVMLAAAGGQDDLLRLLITKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAFVNVQQSNGETALMKACKRGNSDIVRLVIECGADCNILSKHQNSALYFAKQCNNVLVYELLKSHLETLSRVAEETIRDYFESRLALLEPVFPIACHRLCEGPDFSTDFNYMPPQNMPEGSGVLLFIFHANFLGKDVIARLCGPCSVQAVVLNDKFQLPVFLDSHFVYSFSPVAGPNKLFIRLTEAPFAKVKLLIGAYRVQLQ", "length": 858, "molWeight": 97467, "crc64": "17C90A836A416964", "md5": "A9F22287A0AB10A9F56EB7849EB7AAF6"}}
{"primaryAccession": "Q3U1F9", "text": "This is Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 protein, from Mouse, contains 429 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3U1F9", "organism_name": "Mouse", "protein_name": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "length": 429, "firstPublicDate": "2005-12-20", "FUNCTION": "Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells, Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition, Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins, May be involved in cell adhesion signaling", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGPAGSVLSSGQMQMQMVLWGSLAAVAMFFLITFLVLLCSTCDREKKPRQHSGDHENLMNVPSDKDMFSHSATSLTTDALASSEQNGVLTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKAKCHQSRELPRIPPENAVDEILTARAADTELGPGVEGPYEVLKDSSSQENMVEDCLYETVKEIKEVADKGQGGKSKSTSALKELQGAPMEGKADFAEYASVDRNKKCRHSANAESILGTCSDLDEESPPPVPVKLLDENANLPQEGGGQAEEQAAEGTGGHSKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQSAHKPGPCMKGPESACHSMKGLPQRSSSSCNDLYATVKDFEKTPNSISTLPPARRPSEEPEPDYEAIQTLNREDEKVPLETNGHHVPKESDYESIGDLQQCRDVTRL", "length": 429, "molWeight": 46549, "crc64": "F5A95257B4C4DADC", "md5": "3823AA27F9EEC89A59F82009A0662924"}}
{"primaryAccession": "Q3UMU9", "text": "This is Hepatoma-derived growth factor-related protein 2 protein, from Mouse, contains 669 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3UMU9", "organism_name": "Mouse", "protein_name": "Hepatoma-derived growth factor-related protein 2", "length": 669, "firstPublicDate": "2008-02-05", "FUNCTION": "Binds to non-condensed chromatin in the presence of HDGF", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the HDGF family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEADLGCGSDVDKDKESRRVMTVTAVTTTATSDRMESDSDSDKSSDHSGLKRKTPVLKVSVSKRARRASSDLDQASVSPSEEDSESPSESEKTSDQDFTPEKKTAARPPRRGPLGGRKKKKVPSASDSDSKADSDGAKEEPVVTAQPSPSSSSSSSSSSSSDSDVSVKKPPRGRKPAEKPPPKPRGRRPKPERPPSTSSSDSDSDSGEVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEREEKERRKERAERGGSSGEELEDEEPVKKRSRKARGRGTPSSSDSEPEGELGKEGKKLAKKSQLPGSESARKPGQKEKRGRPDEKPRARPVKVERTRKRSEGLSLERKGEKKKEPSVEERLQKLHSEIKFALKVDNPDVRKCLSALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMAKAAEVYTRLKSRVLGPKVEALQKVNKAGAEKERADNEKLEEQPGEQAPRELAEDEPSTDRSAPVNGEATSQKGENMEDRAQEDGQDSEDGPRGGSSEELHDSPRDNSDPAKPGNERQDHERTRLASESANDDNEDS", "length": 669, "molWeight": 74291, "crc64": "01228985D4616848", "md5": "8B6FB72F6F83896CCA3C15B5BF5D5ED7"}}
{"primaryAccession": "Q3UNX5", "text": "This is Acyl-coenzyme A synthetase ACSM3, mitochondrial protein, from Mouse, contains 580 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3UNX5", "organism_name": "Mouse", "protein_name": "Acyl-coenzyme A synthetase ACSM3, mitochondrial", "length": 580, "firstPublicDate": "2007-10-02", "FUNCTION": "Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (PubMed:11470804), Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms (PubMed:11470804)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the ATP-dependent AMP-binding enzyme family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVMLLRARCFQRLAIPDPMRVLYKDYRTATPQNFSNYESMKQDFKIEIPEYFNFAKDVLDQWTNMEKAGKRLSNPAFWWIDGNGEELRWSFEELGLLSRKFANILTEACSLQRGDRVMVILPKIPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKAKCIITDDTLAPAVDAVAAKCENLHSKLIVSQHSREGWGNLKEMMKYASDSHTCVDTKHDEMMAIYFTSGTTGPPKMIGHTHSSFGLGLSVNGRFWLDLIASDVMWNTSDTGWAKSAWSSVFSPWTQGACVFAHYLPRFESTSILQTLSKFPITVFCSAPTAYRMLVQNDMSSYKFNSLKHCVSAGEPINPEVMEQWRKKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKILDENGATLPPGQEGDIALQVLPERPFGLFTHYVDNPSKTASTLRGSFYITGDRGYMDEDGYFWFVARSDDIILSSGYRIGPFEVESALIEHPSIAESAVVSSPDPIRGEVVKAFIVLNPDYKSHDQEQLKKEIQEHVKKTTAPYKYPRKVEFIEELPKTVSGKVKRNELRKKEWVTT", "length": 580, "molWeight": 65623, "crc64": "CAF3D06A0B4A2778", "md5": "92082E2B4471A331DF809E6C0470C46C"}}
{"primaryAccession": "Q3UPP8", "text": "This is Centrosomal protein of 63 kDa protein, from Mouse, contains 700 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3UPP8", "organism_name": "Mouse", "protein_name": "Centrosomal protein of 63 kDa", "length": 700, "firstPublicDate": "2009-09-01", "FUNCTION": "Required for normal spindle assembly (PubMed:24240477), Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity), Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned (By similarity), Also recruits CDK1 to centrosomes (By similarity), Plays a role in DNA damage response (By similarity), Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (By similarity), Promotes stabilization of FXR1 protein by inhibiting FXR1 ubiquitination (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CEP63 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKALRSQLDMKHKEVGILHQQIEEHEKTKQEMAMEYKEELLKLQEELSRLKRSYEKLQKKQLREFRGNTKSFREDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLANRKQKLESVELSSQSEIQHLNSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQDHRQKEEKLRESEKLLEALQEEQKELKASLQSQETFILEAKMQEKLQTTLKAVGTQQSVERPLEDCQKERKYSSPGQGVLDNVLSQLDFSHSSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVEHKEILSQLESLKLENHRLSETVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMSTKSELEHATNMCKKKDGEIFNPAHSRAAGFKNAELKPIHGQHRHDGIKTEQYKTGHHSPRGQTLDSIDPVARGPSPLSSHISPGSSTVSLPSNFLFEAHSLPSVLDINDVNFSDSLSDCMNDQEEFVSSGSLPTSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVRQFTALV", "length": 700, "molWeight": 80449, "crc64": "DAF54534FF243E08", "md5": "E071D66EE8ADCD91058453E97F92D1BB"}}
{"primaryAccession": "Q41739", "text": "This is Thiamine thiazole synthase 2, chloroplastic protein, from Maize, contains 354 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q41739", "organism_name": "Maize", "protein_name": "Thiamine thiazole synthase 2, chloroplastic", "length": 354, "firstPublicDate": "1997-11-01", "FUNCTION": "Involved in biosynthesis of the thiamine precursor thiazole, Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate, The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate, The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme, May have additional roles in adaptation to various stress conditions and in DNA damage tolerance", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the THI4 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATTAASSLLKSSFAGSRLPSATRTTTPSSVAVATPRAGGGPIRASISSPNPPYDLTSFRFSPIKESIVSREMTRRYMTDMITHADTDVVIVGAGSAGLSCAYELSKDPTVSVAIVEQSVSPGGGAWLGGQLFSAMVVRRPAHLFLDELGVGYDEAEDYVVVKHAALFTSTVMSRLLARPNVKLFNAVAVEDLIVRRGRVGGVVTNWALVSMNHDTQSCMDPNVMEAKVVVSSCGHDGPFGATGVKRLQDIGMISAVPGMKALDMNAAEDEIVRLTREVVPGMIVTGMEVAEIDGAPRMGPTFGAMMISGQKAAHLALKALGRPNAVDGTIPEVSPALREEFVIASKDDEVVDA", "length": 354, "molWeight": 37234, "crc64": "452E905B46B6AF13", "md5": "00AD7062B98990AEDD61F14203C8A241"}}
{"primaryAccession": "Q42290", "text": "This is Probable mitochondrial-processing peptidase subunit beta, mitochondrial protein, from Mouse-ear cress, contains 531 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q42290", "organism_name": "Mouse-ear cress", "protein_name": "Probable mitochondrial-processing peptidase subunit beta, mitochondrial", "length": 531, "firstPublicDate": "2006-01-24", "FUNCTION": "Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation, The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase, The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol, In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the peptidase M16 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAMKNLLSLARRSQRRLFLTQATRSSSSFSAIDSVPASASPTALSPPPPHLMPYDHAAEIIKNKIKKLENPDKRFLKYASPHPILASHNHILSAPETRVTTLPNGLRVATESNLSAKTATVGVWIDAGSRFESDETNGTAHFLEHMIFKGTDRRTVRALEEEIEDIGGHLNAYTSREQTTYYAKVLDSNVNQALDVLADILQNSKFEEQRINRERDVILREMQEVEGQTDEVVLDHLHATAFQYTPLGRTILGPAQNVKSITREDLQNYIKTHYTASRMVIAAAGAVKHEEVVEQVKKLFTKLSSDPTTTSQLVANEPASFTGSEVRMIDDDLPLAQFAVAFEGASWTDPDSVALMVMQTMLGSWNKNVGGGKHVGSDLTQRVAINEIAESIMAFNTNYKDTGLFGVYAVAKADCLDDLSYAIMYEVTKLAYRVSDADVTRARNQLKSSLLLHMDGTSPIAEDIGRQLLTYGRRIPTAELFARIDAVDASTVKRVANKYIYDKDIAISAIGPIQDLPDYNKFRRRTYWNRY", "length": 531, "molWeight": 59160, "crc64": "08A3953AD192E6B5", "md5": "DD1B0D7D18997BB9FCA6F356312B5F56"}}
{"primaryAccession": "Q42342", "text": "This is Cytochrome b5 isoform E protein, from Mouse-ear cress, contains 134 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q42342", "organism_name": "Mouse-ear cress", "protein_name": "Cytochrome b5 isoform E", "length": 134, "firstPublicDate": "2001-01-11", "FUNCTION": "Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases, including fatty acid desaturases", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the cytochrome b5 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSDRKVLSFEEVSKHNKTKDCWLIISGKVYDVTPFMDDHPGGDEVLLSSTGKDATNDFEDVGHSDTARDMMDKYFIGEIDSSSVPATRTYVAPQQPAYNQDKTPEFIIKILQFLVPILILGLALVVRHYTKKD", "length": 134, "molWeight": 15084, "crc64": "9CC01C60F7C873FD", "md5": "3E65802210AAF0E49676641EADFBE314"}}
{"primaryAccession": "Q42512", "text": "This is Protein COLD-REGULATED 15A, chloroplastic protein, from Mouse-ear cress, contains 139 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q42512", "organism_name": "Mouse-ear cress", "protein_name": "Protein COLD-REGULATED 15A, chloroplastic", "length": 139, "firstPublicDate": "2015-04-01", "FUNCTION": "Exhibits cryoprotective activity toward stromal substrates (e,g, LDH and rubisco) in chloroplasts and in protoplasts and confers freezing tolerance to plants in a CBF-dependent manner (PubMed:1567390, PubMed:11038526, PubMed:9826741, PubMed:17384167, PubMed:18540080, PubMed:19563440), Protectant against various stresses (e,g, cold, drought and heat stress) by preventing protein aggregation (e,g, LDH) and attenuating enzyme inactivation (PubMed:18540080), Influences the intrinsic curvature of the inner membrane of the chloroplast envelope, and modulates the freeze-induced lamellar-to-hexagonal II phase transitions that occur in regions where the plasma membrane is brought into close apposition with the chloroplast envelope during freeze-induced osmotic contraction (PubMed:9826741), Mediates a shift in the melting curves of phospholipids-containing membranes to lower temperatures (PubMed:20510170), Involved in the regulation of leaf senescence by abscisic acid (ABA) in a VNI2-dependent manner (PubMed:21673078)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the COR15 protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAMSFSGAVLTGMASSFHSGAKQSSFGAVRVGQKTQFVVVSQRKKSLIYAAKGDGNILDDLNEATKKASDFVTDKTKEALADGEKAKDYVVEKNSETADTLGKEAEKAAAYVEEKGKEAANKAAEFAEGKAGEAKDATK", "length": 139, "molWeight": 14605, "crc64": "64EB38CACAD2990B", "md5": "23FDA9B314478322C09D447F41CCCF26"}}
{"primaryAccession": "Q43386", "text": "This is HMG-Y-related protein A protein, from Mouse-ear cress, contains 204 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q43386", "organism_name": "Mouse-ear cress", "protein_name": "HMG-Y-related protein A", "length": 204, "firstPublicDate": "2015-11-11", "FUNCTION": "Binds A/T-rich DNA with a highly dynamic distribution into the nucleus", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the HMGA family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAFDLHHGSASDTHSSELPSFSLPPYPQMIMEAIESLNDKNGCNKTTIAKHIESTQQTLPPSHMTLLSYHLNQMKKTGQLIMVKNNYMKPDPDAPPKRGRGRPPKQKTQAESDAAAAAVVAATVVSTDPPRSRGRPPKPKDPSEPPQEKVITGSGRPRGRPPKRPRTDSETVAAPEPAAQATGERRGRGRPPKVKPTVVAPVGC", "length": 204, "molWeight": 22011, "crc64": "687C24CB6A9AA437", "md5": "F3D57E2783C9FE928B149F57BDB34BE0"}}
{"primaryAccession": "Q43725", "text": "This is Cysteine synthase, mitochondrial protein, from Mouse-ear cress, contains 430 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q43725", "organism_name": "Mouse-ear cress", "protein_name": "Cysteine synthase, mitochondrial", "length": 430, "firstPublicDate": "1997-11-01", "FUNCTION": "Acts as a cysteine synthase, Plays a role in the sulfide detoxification in mitochondria", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the cysteine synthase/cystathionine beta-synthase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVAMIMASRFNREAKLASQILSTLLGNRSCYTSMAATSSSALLLNPLTSSSSSSTLRRFRCSPEISSLSFSSASDFSLAMKRQSRSFADGSERDPSVVCEAVKRETGPDGLNIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERYLSTPLFQSIREEVEKMQPEV", "length": 430, "molWeight": 45815, "crc64": "9DDEB1B8E314E143", "md5": "15146CDE4C7A20B6E1C72407C06EF409"}}
{"primaryAccession": "Q49B93", "text": "This is Sodium-coupled monocarboxylate transporter 2 protein, from Mouse, contains 619 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q49B93", "organism_name": "Mouse", "protein_name": "Sodium-coupled monocarboxylate transporter 2", "length": 619, "firstPublicDate": "2008-05-20", "FUNCTION": "Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter, Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate, May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine, May play also a role in monocarboxylates transport in the retina, Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the sodium:solute symporter (SSF) (TC 2,A,21) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRVKNFEAWDYVVFAGLFVISSGIGVFFAIKERKKTTSREFLVGGRQMSFGPVALSLTASFMSAVTVLGTPAEVYRFGASFFLFLISYVFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYIVQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSNHVGGFNNVLEKAGNGSRLHIVDFDVDPLRRHTFWTITIGGTFTWLGVYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVACAVFSGLIMYSHFKDCDPWTSGVISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPHLSDKLSTWISKGLCILFGIMCTSMAVVASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGALGGLLTGITLSFWVAIGSFIYPAPESKTLPLPLSTEHCVELNITTTVAPQISSRPVLADTWYSLSYLYFSAVGCLGCIAAGIIISFLTGKQRGKDIDPLLIRPVCNLFCFWSKKYKTLCWCGVQHDRETEQDYLDSGSAWKQGVESGLQNGLKQDTLAQIPGYNPKEKSYSNSVPEKTTYF", "length": 619, "molWeight": 67951, "crc64": "B1C36211590A511A", "md5": "E85733BD6DC06FFBC48FF8F47522D1CD"}}
{"primaryAccession": "Q4JL84", "text": "This is Transcription factor MYB59 protein, from Mouse-ear cress, contains 235 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q4JL84", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor MYB59", "length": 235, "firstPublicDate": "2006-05-16", "FUNCTION": "Transcription factor", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKLVQEEYRKGPWTEQEDILLVNFVHLFGDRRWDFVAKVSGLNRTGKSCRLRWVNYLHPGLKRGKMTPQEERLVLELHAKWGNRWSKIARKLPGRTDNEIKNYWRTHMRKKAQEKKRPMSPTSSSSNCCSSSMTTTTSQDTGGSNGKMNQECEDGYYSMDDIWREIDQSGANVIKPVKDNYYSEQSCYLNFPPLASPTWESSLESIWNMDADESKMSSFAIDQFPLSFEHGSGRL", "length": 235, "molWeight": 27237, "crc64": "35DB85B37C7CFC66", "md5": "4C9378AA105D4CD48BD194B2B4CCB77E"}}
{"primaryAccession": "Q4R1C4", "text": "This is Exo-beta-D-glucosaminidase protein, from Trichoderma reesei, contains 892 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q4R1C4", "organism_name": "Trichoderma reesei", "protein_name": "Exo-beta-D-glucosaminidase", "length": 892, "firstPublicDate": "2010-10-05", "FUNCTION": "Hydrolyzes chitosan and chitooligosaccharides with retention of anomeric configuration, Has no activity against beta-D-galactoside, beta-D-glucuronide, beta-D-mannoside, chitin, glycol chitosan, cellulose, N,N'-diacetylchitibiose and pNP-GlcNAc", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLANAIAALLLGSGIASAAGHGSPLTSKAGHRAVIPDWDLKSSSDVSKDLGGLSKPGVDTSSWYHAGTSRCTIMGCLINAGVYNDEELWYSDNLNHVNWGQFSVPWVYRHEFALSPAKGKHFLLQTNGITSKADLFFNGKQIADKEYQSGAYAGRTYDITNLAAKKNALLVQVYPTDYLYDFALGYVDWNPYPSDNGSGIWRDITIKETGSVSMGPVSVLVDIDVPVEKNPARVTVRAEAQNLESHAVEFNAAAVISGNSCSGEALKQTIKLAPGEKKLVQFTQTIKTPSIWWPKQWGDQPLYTAEVTFSVKGAVSDTAQTKFGVRKVTSFVNQFNDTQYSVNGHPFQVIGGGYGADMFLRWDSERFTRIVEYMLDMHQNTIRLEGKMEHPELYEICDEYGLMVMPGWECCDKWEAWAYNDELAIFPPPVWDANDYETANYSMIHEAAMMQPHPSVLTFLVGSDFWPNDEAVVLYANALKNAGWQTPIIASASKRGFPALLGPGGMKMDGPYDWVPPNYWYDVEPSEDRLGAAFGFGSELGAGVGTPELSSLRRFLNQSDLDDLWKNPNKNLFHMSTNASSFYNRKIYNQGLWKRYGAPTSLDDYLLKAQMMDYEATRAQYEGFGALWTASRPATGVIYWMLNNAWPSLHWNQFDYYLHPAGSYFGTKVGSRIEHVAYNYQKKEIWVINHSLYQTGSRNIKVELIDMNGKQIAKKLVQVRTKANSGFKAMDISSDINKLSSVAFLRLVLSDEKGSVLSRNVYWVTKTIDELNWDESTWYYTPVSKFVDYTPLNTLATAQVSVTTSGGKHLPGIPGSQTRTVTLENKSSVPAVFIRLTLVDSKGNDVNPVSWSDNYVTLWPHEKLQLEVGGWDGSGDKIQISGKNIKATTVKL", "length": 892, "molWeight": 99428, "crc64": "AA91240261C26570", "md5": "2ACD4D9816F316BF5814011D12A73518"}}
{"primaryAccession": "Q4W6B5", "text": "This is Mitochondrial-processing peptidase subunit beta protein, from Social amoeba, contains 469 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q4W6B5", "organism_name": "Social amoeba", "protein_name": "Mitochondrial-processing peptidase subunit beta", "length": 469, "firstPublicDate": "2010-01-19", "FUNCTION": "Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable), Preferentially, cleaves after an arginine at position P2 (By similarity), Plays an essential role in mitochondrial biogenesis (PubMed:18603769)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the peptidase M16 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSNITKLFVKSTKNFSRSFSRKTVDPSYLKISPETKITTLSNGIRVATEQTYGEVASVGVWVDSGSVYETDKNNGVAHFLEHMIFKGTAKRPTPQSIETEIENMGGSLNAFTSREHSAYYMKVLKDNVPNAVDILSDILQNSKFETSLIEQERDTILSENDYIQSKEDEVVFDQLHAAAFQGSALGRTILGPVENIKSITREQIQEFINENYTGDRLVISAAGAVNHEQLVEQVKEKFANVKMSQVSKDVKRAAITNDFIGSELRVRDDEQPLIHFAVAVRALPWTDPDYFVLELIQTMIGNWNRGIAAGKNIASNLGEIVATEDLAESYSTFFTCYQDTGLFGNYGVCQPERVDDLVAEMLKEWQRIATSCNKNEVERNKQKLLATTLMQYDGTSKVCEGIGRQILTLGRRLSPFEVYTRINEITVADVQRVASTLLRDVSPAVTAIGPIANYPDYNFVKGWTYWNRL", "length": 469, "molWeight": 52626, "crc64": "404154C4C47DF92D", "md5": "A5AE13649E949BC1CA6769C39AA6AC5F"}}
{"primaryAccession": "Q4ZJN1", "text": "This is Complement C1q and tumor necrosis factor-related protein 9 protein, from Mouse, contains 333 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q4ZJN1", "organism_name": "Mouse", "protein_name": "Complement C1q and tumor necrosis factor-related protein 9", "length": 333, "firstPublicDate": "2007-06-26", "FUNCTION": "Probable adipokine, Activates AMPK, AKT, and p44/42 MAPK signaling pathways", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRIWWLLLVMGACTRSVFSQDTCRQGHSGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGHPGGPGKDGIRGEKGEPGADGRVEAKGIKGDPGSRGSPGKHGPKGSIGPTGEQGLPGETGPQGQKGDKGEVGPTGPEGLMGSTGPLGPKGLPGPMGPIGKPGPRGEAGPMGPQGEPGVRGMRGWKGDRGEKGKVGEAPLVPKSAFTVGLTVISKFPPPDAPIKFDKILYNELNHYNVATGKFTCHVAGVYYFTYHITVFSRNVQVSLVKNGVKVLHTKDSYMSSEDQASGGIVQELKLGDEVWMQVTGGERFNGLFADEDDDTTFTGFLLFSSS", "length": 333, "molWeight": 34566, "crc64": "7F68661C0A6841F3", "md5": "7D9B22C7A4DF21C703694490C1334C06"}}
{"primaryAccession": "Q501B2", "text": "This is bZIP transcription factor 16 protein, from Mouse-ear cress, contains 409 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q501B2", "organism_name": "Mouse-ear cress", "protein_name": "bZIP transcription factor 16", "length": 409, "firstPublicDate": "2016-02-17", "FUNCTION": "Transcriptional activator that binds to the G-box motif (5'-CACGTG-3') and other cis-acting elements with 5'-ACGT-3' core, such as Hex, C-box and as-1 motifs, Possesses high binding affinity to G-box, much lower affinity to Hex and C-box, and little affinity to as-1 element (PubMed:18315949), G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control (Probable), Binds to the G-box motif 5'-CACGTG-3' of LHCB2,4 (At3g27690) promoter, May act as transcriptional repressor in light-regulated expression of LHCB2,4, Binds DNA as monomer, DNA-binding activity is redox-dependent (PubMed:22718771)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASNEMEKSSKEKEPKTPPPSSTAPPSSQEPSSAVSAGMATPDWSGFQAYSPMPPPHGYVASSPQPHPYMWGVQHMMPPYGTPPHPYVAMYPPGGMYAHPSMPPGSYPYSPYAMPSPNGMTEVSGNTTGGTDGDAKQSEVKEKLPIKRSRGSLGSLNMITGKNNEPGKNSGASANGAYSKSGESASDGSSEGSDGNSQNDSGSGLDGKDAEAASENGGSANGPQNGSAGTPILPVSQTVPIMPMTAAGVPGPPTNLNIGMDYWGAPTSAGIPGMHGKVSTPVPGVVAPGSRDGGHSQPWLQDDRELKRQRRKQSNRESARRSRLRKQAECDELAQRAEVLNEENTNLRAEINKLKSQCEELTTENTSLKDQLSLFPPLEGISMDNDHQEPDTNQTGAAERKVDSYKDST", "length": 409, "molWeight": 43109, "crc64": "5C687D6938077C67", "md5": "42CC1B792605A58F9FECDE3E85FD1006"}}
{"primaryAccession": "Q53EK2", "text": "This is Non-structural maintenance of chromosomes element 1 protein, from Fission yeast, contains 232 amino acids, has 1 RING-type; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [181, 222], "description": "RING-type; atypical", "keyword_description": "Zinc finger", "textural_description": "RING-type; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q53EK2", "organism_name": "Fission yeast", "protein_name": "Non-structural maintenance of chromosomes element 1", "length": 232, "firstPublicDate": "2005-10-25", "FUNCTION": "Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage, Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks, Plays a critical role in meiosis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the NSE1 family", "domain_description": {"RING-type; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEKERQDGLSDKHKFILQYIMCRTAGVDNEQVRELVQEQYGETATVEDVINELNNSLHNFDFKIKRVQDQLDGRLTLHFQNLSGDPVSQMATPYPPVQIELMRKIIEWIMKCDDYQYSLTTLQIQKLSRKEMGLAPSVIESHLHTFERDGWLRQREGIWTFTNHALAELDAYLHNEYESNLYECNACREIVIAGYVCDCGYCLHVYCCKHLAHVNCINCNTPWANATVIGRW", "length": 232, "molWeight": 27052, "crc64": "9255E146B354CEA8", "md5": "8913086A63D09011227287DE3993864A"}}
{"primaryAccession": "Q53HC0", "text": "This is Coiled-coil domain-containing protein 92 protein, from Human, contains 331 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q53HC0", "organism_name": "Human", "protein_name": "Coiled-coil domain-containing protein 92", "length": 331, "firstPublicDate": "2007-02-06", "FUNCTION": "Interferon-stimulated protein that plays a role in innate immunity, Strongly inhibits ebolavirus transcription and replication, Forms a complex with viral RNA-bound nucleocapsid NP and thereby prevents the transport of NP to the cell surface", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTSPHFSSYDEGPLDVSMAATNLENQLHSAQKNLLFLQREHASTLKGLHSEIRRLQQHCTDLTYELTVKSSEQTGDGTSKSSELKKRCEELEAQLKVKENENAELLKELEQKNAMITVLENTIKEREKKYLEELKAKSHKLTLLSSELEQRASTIAYLTSQLHAAKKKLMSSSGTSDASPSGSPVLASYKPAPPKDKLPETPRRRMKKSLSAPLHPEFEEVYRFGAESRKLLLREPVDAMPDPTPFLLARESAEVHLIKERPLVIPPIASDRSGEQHSPAREKPHKAHVGVAHRIHHATPPQAQPEVKTLAVDQVNGGKVVRKHSGTDRTV", "length": 331, "molWeight": 36961, "crc64": "840D062480338500", "md5": "CC69EBE1F3867EA1A156872501F4891D"}}
{"primaryAccession": "Q53R12", "text": "This is Transmembrane 4 L6 family member 20 protein, from Human, contains 229 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q53R12", "organism_name": "Human", "protein_name": "Transmembrane 4 L6 family member 20", "length": 229, "firstPublicDate": "2006-10-03", "FUNCTION": "Polytopic transmembrane protein that inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthesis (PubMed:25310401, PubMed:27499293), In response to ceramide, which alters TM4SF20 membrane topology, stimulates RIP activation of CREB3L1 (PubMed:27499293), Ceramide reverses the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20, this mechanism is called 'regulated alternative translocation' (RAT) and regulates the function of the transmembrane protein (PubMed:27499293)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the L6 tetraspanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTCCEGWTSCNGFSLLVLLLLGVVLNAIPLIVSLVEEDQFSQNPISCFEWWFPGIIGAGLMAIPATTMSLTARKRACCNNRTGMFLSSLFSVITVIGALYCMLISIQALLKGPLMCNSPSNSNANCEFSLKNISDIHPESFNLQWFFNDSCAPPTGFNKPTSNDTMASGWRASSFHFDSEENKHRLIHFSVFLGLLLVGILEVLFGLSQIVIGFLGCLCGVSKRRSQIV", "length": 229, "molWeight": 25075, "crc64": "1718E0594997A1A1", "md5": "A03BED3565D68A2E3554BF9746C853D8"}}
{"primaryAccession": "Q53R41", "text": "This is FAST kinase domain-containing protein 1, mitochondrial protein, from Human, contains 847 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q53R41", "organism_name": "Human", "protein_name": "FAST kinase domain-containing protein 1, mitochondrial", "length": 847, "firstPublicDate": "2007-04-17", "FUNCTION": "Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the FAST kinase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKKTPVFLESLVTNMLRLRAICPFSWRVFQFRPISCEPLIIQMNKCTDEEQMFGFIERNKAILSEKQVGCAFDMLWKLQKQKTSLLKNAEYVRDHPQFLTLHNLATNKFKLMNDDTLVNVLYVTQQFAGEAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQHLYFSPLMGKIADIVHRNLETTQDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNVRYRYQPLLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPLCNHPASFVKLFVALGPIAGPEEKKQLKSTMLLMSEDLTGEQALAVLGAMGDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQELTFLHFQRKEFFAKLRELLLSYLKNSFIPTEVSVLVRAISLLPSPHLDEVGISRIEAVLPQCDLNNLSSFATSVLRWIQHDHMYLDNMTAKQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSLKGNTFPESLLEEMIATLQHFMDDINYINVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIPAIIRPFSVLNYDPPQRDEFLGTCVQHLNSYLGILDPFILVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQFHLMELNRSVCLECPEFQIPWFHDRFCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKASVLTPYYHKVDFECILDKRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALEFLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRECIFGEVKSCL", "length": 847, "molWeight": 97411, "crc64": "5026A635048EB0B3", "md5": "2941022A2BC2F387FAA7BECB239126E2"}}
{"primaryAccession": "Q54ER9", "text": "This is Basic-leucine zipper transcription factor B protein, from Social amoeba, contains 602 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q54ER9", "organism_name": "Social amoeba", "protein_name": "Basic-leucine zipper transcription factor B", "length": 602, "firstPublicDate": "2009-09-22", "FUNCTION": "Transcriptional regulator involved in DIF-1 signaling, DIF-1 (Differentiation Inducing Factor-1) is a signal molecule involved in the differentiation of pstO (prestalk-O) cells (By similarity), May be a direct activator of ecmA", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNQFYQSTTGGQQNNNNGNQFQQYQPQQQQQFQQYSPSNANNNNTTTTTTTSTSKKGKNKDNQSKQQQIQQQQIQQQQQQQQQQQQQIQQQSVDTPSSYNGDGSDDGSDTERENKKNRNRVNQNLASRNYRQRKKEYIKEIEEKLAVLALENDQLKKENINLKKGGGVEIMKPDPAFITMMMEAKQIIIQLDVAIKKNDERSLIYLLQLFHLSIEKRHTIVEREVEKMVHPYTQAKLAAMGYVPSLENPMISSISGPSSDGWWTMYISEAQITEEQAKAIKQLRSNHWKADIELRNEREKLDRSIKEFYLNRVMVFPTNERLNKSFATNLSLSDGPNPTSPNSSSVTQSTLVRPSPGLTLLNNLNEENNNSNNSSNSSNNNTTTNNNNNNSLTPTPNQNNNISNIAVNGTISVVNELGFSPINGNIDISEILEFTRKLEALKKNFVKQRTLMEDTHSALSSILTPKQEAMLLVRVHSSTRYDFANMEMLKNVWGSVIAKDTTSYPQPPTFSQQTQQLQQAQLQLQNQTKQQQQQLQNNNNNNNNNNNNNNSFNNSNNNNVQNNSSNPSTPGGNNDQQNIYYTSSPSIPSSPYNHHQQQPSRQ", "length": 602, "molWeight": 68452, "crc64": "421BB044C02B5D16", "md5": "28D8AE1C285386A44EBD3CD770BFC9DC"}}
{"primaryAccession": "Q54JH4", "text": "This is P2X receptor E protein, from Social amoeba, contains 388 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q54JH4", "organism_name": "Social amoeba", "protein_name": "P2X receptor E", "length": 388, "firstPublicDate": "2009-12-15", "FUNCTION": "P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling, Not required for the purinergic response to extracellular nucleotides, Not essential for osmoregulation, Inward currents evoked by intracellular ATP, ATP analog beta, gamma-imido-ATP is a weak partial agonist of p2xE, Exclusively selective for ATP over other nucleotides, Insensitive to copper and P2 receptor antagonists PPADS and suramin but strongly inhibited by sodium ions, More permeable to ammonium than either sodium or potassium ions and less permeable to choline, Permeable to calcium ions, but not chloride", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the P2X receptor family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNFRNIDWDSLFSYSTIKIVRIRDKRLGILHFAFLIGIILYIIVGTIFLQKKYLVLESPIGSIRTSLMAPSVKPTDLPYCLKNGTDTSYDGYPNKPCQYWDEYLVLYPPSEESSMFITTRCTQETQSTVNGCNLSEPTCVYNTTSSSDFYIANVENFTILLDHTLSAPSLGIQYNGAQLNGQLLDTDGNPMSLPPPNIVGVKGSPDIMSLQGVLTAAGVESLDSQGLANKSRTIRDDGILILCFITYSNTYTYNTGNYHYTYQFKLVQNTKYKIVEPVFTKDVEDRYIFDRHGVRIIFIQTGQLGQFDFQTMLLTFVSGIGLVTAASLIVDIIATRIMPQRSRYQELKFQDSSINNTQKTPTNDHTPLLKDNEDTINENSYQNNSYEK", "length": 388, "molWeight": 43829, "crc64": "8EB448F9E0A4D256", "md5": "ECB28ABAE026CDAC97AA98E6B87CA5B7"}}
{"primaryAccession": "Q54NL4", "text": "This is Vacuole membrane protein 1 homolog protein, from Social amoeba, contains 403 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q54NL4", "organism_name": "Social amoeba", "protein_name": "Vacuole membrane protein 1 homolog", "length": 403, "firstPublicDate": "2008-04-08", "FUNCTION": "Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes (By similarity), Required for autophagosome formation: participates in early stages of autophagosome biogenesis at the endoplasmic reticulum (ER) membrane by reequilibrating the leaflets of the ER as lipids are extracted (By similarity), In addition to autophagy, involved in other processes in which phospholipid scramblase activity is required (PubMed:18550798)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the VMP1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGKSNTIVLSNEKDIQLRIQQLEERKEKRKNVKLLFSPIKTTKYFLYILKDTLVSGIRYFQTRPFLLFFIALFASLTFIAVYVPGEHQKYMGKYSDLISDCIWWVGLGVLSSIGLGTGLHTFVLYLGPHIAKVTLAATEWNSVNFNVYGANSFIQPATAMIGGVSFWMILQKVQWAALFWGAGTAIGELPPYFVARTARLKGLKLEQEKKLKEQQEKPIDEKDQPKKGLLERLSEKVPALIGNLGFFGILAFASIPNPLFDLAGITCGHFLVPFWKFFGATFIGKAVVKAHIQACFVILAFNMETLTMVISFIEDKIPFLKNKIQPILEKERQKLNSTVSANSPKSLVGLAWDCVLFLMISYFLMSIVDSSVQEYLIEKDNKKIELLKSKLEKQQPKETKKTK", "length": 403, "molWeight": 45612, "crc64": "2B2CE6159AC8105A", "md5": "44DFF987D3DDA3C5A4E150E4D987C14C"}}
{"primaryAccession": "Q54QR9", "text": "This is Protein phosphatase 2A scaffold subunit protein, from Social amoeba, contains 584 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q54QR9", "organism_name": "Social amoeba", "protein_name": "Protein phosphatase 2A scaffold subunit", "length": 584, "firstPublicDate": "2009-03-24", "FUNCTION": "Scaffolding molecule which may coordinate the assembly of the catalytic subunit and a variable regulatory B subunit (PubMed:20493808), Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay (PubMed:20493808), The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway (PubMed:20493808)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the phosphatase 2A regulatory subunit A family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASINTESDDYHPIVILIDELKNEDIQLRLNSIKKLQSIAKALGPERTRTELIPYLQDSVLEDEDEVLVVLSEELGNLIEFVGGAEHAVCLLPPLQILAGAEELVVREKAVESLCKIAKEIPTSSFEESFLPLLFSLSKADWFTSRTSACGLFTVSYPRANAEMKKSLRKTFGGLCHDDTPMVKRAAATNLGSFAKQIEKESVKSEILPLFQSLSTDEQDSVRLLGVENCALLGSMLTNEENIQFILPTIKASSLDKSWRVRYMVARLLKELCESMGTEITKTELIGAFVKLLKDTEAEVRTEASLRIADVCSLLTKEMNIKTILPCVKDLVSDSSQHVRAALAQVIMSLAPIYGKEDTLTHLLELFLHLLKDDFPDVRLNIISKLDQVSKVIGIEMLSQSLLPAIVELAEDHQWRVRLAIIDYIPLLASQLGVEFFDEKLGNLCMTWLGDPVFSIREAATNNLKKLTEVFGVDWAKNNIIPKVLSLHSHPNYLYRMTTLFSISTLSTVVGGDVISSSMVPLLAKMVSDKVPNIRFNVAKTFQTIIPLLDSTIVQSRVKPLLVKLHEDTDKDVKFYASQALQLC", "length": 584, "molWeight": 65076, "crc64": "74A4AB12F62A359F", "md5": "D57C8D15829843046ECB97E9CCEF75D9"}}
{"primaryAccession": "Q54RP0", "text": "This is UDP-galactose:fucoside alpha-3-galactosyltransferase protein, from Social amoeba, contains 648 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q54RP0", "organism_name": "Social amoeba", "protein_name": "UDP-galactose:fucoside alpha-3-galactosyltransferase", "length": 648, "firstPublicDate": "2008-04-08", "FUNCTION": "Specifically catalyzes the transfer of a galactosyl residue to the hydroxyproline-linked saccharide on Skp1 protein (fpaA/fpaB), Catalyzes the formation of a Gal-alpha-1,3-Fuc linkage, leading to Gal-Fuc-Gal-GlcNAc-HyPro143-Skp1", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the glycosyltransferase 77 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEKKVEYIKENDKIVLMCNYGFRDMTLNLLKCFEKLSIDKSRYILYCMDDKAYQFFAEFKGIECQRFSRDDIINSSTSSTQLFHDNNTNDNKGIYSENAESYGDIGFRAICNEKPLVVLDVLKKGYNVLWTDTDIVWKRDPFIHFYQDINQENQFTNDDDIDLYVQQDDDDICAGFYFIRSNQRTIKFIQDSINFLNPCIDDQIAMRLFLKSQGINIKSKNILLSLSENDKKDKIRYRLLDKKLFPNGTNYFNLKITQRDNITPFIIHNNCIIGHRSKKDRFIEYGLWYINDDEIDINSNINNDDENNKEIKLFKNVLKNHTDIITSINSSDDGKLFTTSIDKSIKIWKFENTSGNDTDNGIFKVLKSKYIHKRGGIWSTFIFSSNNNNNNDYGFENLLTSSHDKTIQYWDNNLQVIQTFIGHTGIINQLIVIPNSSYFFTCSDDNTIRQFDLNNINFKRVFIGHNGWVSSIAINKNLNTLYSCSNDGTIRFWDINSGRCLNIIKGNQGGWIRKIIYNDNLNQLISGGNDGTIKIWSCDNLNNFNDNQYLLKINTNENSSINDLQFDSDTNLIYCAFENGSLKSFKLTSNNNNNNNNNNNNNNNTINYSLDKVYQGHLNSSINCIHISKSLNLLFSGGFDKQIKSWDL", "length": 648, "molWeight": 75244, "crc64": "1A92113B7C48E9D4", "md5": "BF6B51551525084CD5B90E3881DCD1F6"}}
{"primaryAccession": "Q54RR8", "text": "This is Phosphorelay intermediate protein rdeA protein, from Social amoeba, contains 254 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q54RR8", "organism_name": "Social amoeba", "protein_name": "Phosphorelay intermediate protein rdeA", "length": 254, "firstPublicDate": "2009-06-16", "FUNCTION": "Phosphorelay protein that supplies phosphate to regA or accepts phosphate from regA; depending on the relative concentration of the phosphodonor proteins, In vitro, acts as a substrate for cheA (bacterial kinase), Plays a role in the development, ypd1 (yeast) can complement rdeA defect", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MISDYEGPTPTKKFDQDILFDYSEGEKEFTFELLDSYISSVEEHLPELLNSFEAKDLKGAVLHSHDIKGSSSYIGCEAVRYVSGKIEAYCKNDELEKAESFYPELKKEVEEVFKILSDFKKNWDKNHGEGGSDDGGDDNESEPTENNNNDGSSVNNNDSSSGGGGKDIENKNTDENTGKNLNERSKSPVPLQTTLKPVTIETPKTASDKIATETPTSLANNTNSSSNNNSKNENGLNSKQPQTSSNSPTKIQTK", "length": 254, "molWeight": 27893, "crc64": "E90310BE26924E76", "md5": "D4DA51FAE8E989D8093ECF1585799193"}}
{"primaryAccession": "Q553Y1", "text": "This is P2X receptor B protein, from Social amoeba, contains 369 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q553Y1", "organism_name": "Social amoeba", "protein_name": "P2X receptor B", "length": 369, "firstPublicDate": "2009-12-15", "FUNCTION": "P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling, Not required for the purinergic response to extracellular nucleotides, Not essential for osmoregulation, Inward currents are evoked by intracellular ATP and ATP analogs, Insensitive to the P2 receptor antagonists PPADS and suramin, and also copper ions, Inhibited by sodium ions, Permeable to chloride ions", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the P2X receptor family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTIDWDSILSYNTIKVVRIRDRRLGILHLCFLIVIVLYVVVYSAIIKKGYVTTEEPVGSIRTSLLAPDELKSNQAYCKNNTEPYPYEKLDCVYYDEKLALFPIGDDVGFTASTRMRISDQTVNCSLMNPSCKFYTNTSMNVYLADIESFTVLIDHTMYAPSSQIQFNGDDLSGYVLDQNGNEIQLNESVNTIGVQGKPDILQLGKLLEFAGVDLDGPSLVNSSNSIRYDGCVLFVFIEYSNTFSYDLKKIKYVYSIKKVDDTAYDVPEVIILNNENSRLYYKRHAIRLIFIQTGVIGSFNFQSLLLTLVSGLGLLTVSTLIVDQLAIRFLPQRKSYSSLKFQTTESFRMKKKIVNDDGEDKLYHNIEAL", "length": 369, "molWeight": 41871, "crc64": "52C76B9970D4C483", "md5": "F836C7942DB7057A73C4EE254BDF3553"}}
{"primaryAccession": "Q55P57", "text": "This is Laccase-1 protein, from Filobasidiella neoformans, contains 624 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q55P57", "organism_name": "Filobasidiella neoformans", "protein_name": "Laccase-1", "length": 624, "firstPublicDate": "2016-04-13", "FUNCTION": "Laccase that catalyzes the oxidation of certain aromatic compounds, including L-dopa, to quinones, which then polymerize to melanin (PubMed:1100669, PubMed:6807845, PubMed:6804444, PubMed:8760791), Able to oxidize a wide variety of aromatic diphenol and diamino groups in the ortho, meta, and para positions but not monophenolic groups such as in phenol, tyramine, or tyrosine (PubMed:8300520), Plays an important role in virulence (PubMed:8760791), Plays a role in dissemination to extrapulmonary sites but is not involved in pulmonary growth or in elicitation of cellular immune responses in the lung (PubMed:14977977)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the multicopper oxidase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGLAKLFFLSCSFVSLVSSEKTDESPTAVSDNYMPKATATIDPSVFALSNDFEITDVPTTREYTFDIAKAFASPDGYEREVYVVNNMFPGPVIEANTGDTIIVHVNNHLDEGQSLHWHGLRQLGTAFMDGVPGITQCPIPPGGSFTYNFTVSHQSGTYWWHSHYSNSMADGIWGPLIVHSPNEPLQRGRDYDEDRIVFITDWMHDNSEIIIAALATPEGYKGNIAPPQGDAILINGRGQTNCTATGSSSCFYPPPPEIQVPVNCRVRLRFISATAHPMYRISIDNHPMEVVEADGTAVYGPTVHEISVAPGERYSAIINTNEGKEGDAFWLRTSVALSCMFGAVSQEGLAVVRYTGNGMVSTEEPQTSAWSDLAGVTVPCTGLDQTYTLSPRDSLSAPREPLQSHFFNSERGAFVNVLGNTFQGYGFNNISYQNQIFNPLLSIVQRGGSCENTLVSSRTFPDFGPGNIIINNLDTVIDHPYHLHGNEFQVIGRGTGALSIDNLTNIDFTLDNPVRKDTLWIQGGSWAVLRITADNPGVWALHCHIGWHLTEGKLAVIVVQPSAIGHMESPESWTNLCANTDPNAFGPAKRSSSPSIQSSKTSSFQYLREVKGKVVKRRGAREA", "length": 624, "molWeight": 68270, "crc64": "A675C03F8940224B", "md5": "38AC8BDDBE12E1F78F622F622B301EA3"}}
{"primaryAccession": "Q569K4", "text": "This is Zinc finger protein 385B protein, from Human, contains 471 amino acids, has 4 Matrin-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [34, 64], "description": "Matrin-type", "keyword_description": "Zinc finger", "textural_description": "Matrin-type Zinc finger"}, {"location": [157, 187], "description": "Matrin-type", "keyword_description": "Zinc finger", "textural_description": "Matrin-type Zinc finger"}, {"location": [282, 316], "description": "Matrin-type", "keyword_description": "Zinc finger", "textural_description": "Matrin-type Zinc finger"}, {"location": [348, 378], "description": "Matrin-type", "keyword_description": "Zinc finger", "textural_description": "Matrin-type Zinc finger"}], "meta_data": {"primaryAccession": "Q569K4", "organism_name": "Human", "protein_name": "Zinc finger protein 385B", "length": 471, "firstPublicDate": "2005-10-25", "FUNCTION": "May play a role in p53/TP53-mediated apoptosis", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"Matrin-type Zinc finger": 4}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNMANFLRGFEEKGIKNDRPEDQLSKEKKKILFSFCEVCNIQLNSAAQAQVHSNGKSHRKRVKQLSDGQPPPPAQASPSSNSSTGSTCHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALDATKNKPKMVPSKDSAKANPSCSITPITGNNSDKSEDKGKLKASSSSQPSSSESGSFLLKSGTTPLPPGAATSPSKSTNGAPGTVVESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDMMKPLAPAFLSSPLAAAAAVSSALSLPPRPSASLFQAPAIPPALLRPGHGPIRATPASILFAPY", "length": 471, "molWeight": 50407, "crc64": "052813B99B908515", "md5": "873AE8B722833C4670BE03915D1894BB"}}
{"primaryAccession": "Q569Z6", "text": "This is Thyroid hormone receptor-associated protein 3 protein, from Mouse, contains 951 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q569Z6", "organism_name": "Mouse", "protein_name": "Thyroid hormone receptor-associated protein 3", "length": 951, "firstPublicDate": "2006-05-16", "FUNCTION": "Involved in pre-mRNA splicing, Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC), Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC) recognition, May be involved in nuclear mRNA decay, Involved in regulation of signal-induced alternative splicing, During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells, Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA, Involved in response to DNA damage, Is excluced from DNA damage sites in a manner that parallels transcription inhibition; the function may involve the SNARP complex, Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex; however, it is not regarded as a stable Mediator complex subunit, Cooperatively with HELZ2, enhances the transcriptional activation mediated by PPARG, maybe through the stabilization of the PPARG binding to DNA in presence of ligand, May play a role in the terminal stage of adipocyte differentiation, Plays a role in the positive regulation of the circadian clock, Acts as a coactivator of the CLOCK-BMAL1 heterodimer and promotes its transcriptional activator activity and binding to circadian target genes (PubMed:24043798)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the BCLAF1/THRAP3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSVSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSTKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDIKGSESSKPWPDATTYGAGSASRASVSDLSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSNASQMGSSMSGGAGYQSGAHQGQFDHGSGSLSPSKKSPVGKSPPATGSAYGSSQKEESAASGGAAYSKRYLEEQKTENGKDKEQKQTNADKEKLKEKGGFSDADVKMKSDPFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEELDEHDKDKSKGRKEPEFDDEPKFMSKVIAGASKNQEEEKSGKWESLHTGKEKQRKAEEMEDEPFTERSRKEERGGSKRSESGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGSKGDFSSGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGNEQEAAKNKKSPEIHRRIDISPSTFRKHGLTHEELKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSTEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYPEEAEEREESTSGFDKSRLGTKDFVGPNERGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRSREEEWDPEYTPKSKKYYLHDDREGEGSDKWMGRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDSLQPSAE", "length": 951, "molWeight": 108178, "crc64": "40DF483027363B4E", "md5": "8E22806C0266C7B1A45363CBB214EA59"}}
{"primaryAccession": "Q56WN1", "text": "This is Glutamine synthetase cytosolic isozyme 1-1 protein, from Mouse-ear cress, contains 356 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q56WN1", "organism_name": "Mouse-ear cress", "protein_name": "Glutamine synthetase cytosolic isozyme 1-1", "length": 356, "firstPublicDate": "2006-06-13", "FUNCTION": "High-affinity glutamine synthetase which catalyzes the synthesis of glutamine from ammonium and glutamate (PubMed:14757761), May contribute to the homeostatic control of glutamine synthesis in roots", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the glutamine synthetase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSLVSDLINLNLSDSTDKIIAEYIWVGGSGMDMRSKARTLPGPVTDPSQLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRRGNNILVMCDAYTPAGEPIPTNKRHAAAKVFSNPDVAAEVPWYGIEQEYTLLQKDVKWPVGWPIGGYPGPQGPYYCGIGADKSFGRDVVDSHYKACLYAGINISGINGEVMPGQWEFQVGPAVGISAADEIWVARYILERITEIAGVVVSFDPKPIPGDWNGAGAHCNYSTKSMREEGGYEIIKKAIDKLGLRHKEHIAAYGEGNERRLTGHHETADINTFLWGVANRGASIRVGRDTEKEGKGYFEDRRPASNMDPYIVTSMIAETTILWNP", "length": 356, "molWeight": 39115, "crc64": "AE54FB88287CFE9D", "md5": "B099AB6FAAAAE584C52CAEA7661A0D0C"}}
{"primaryAccession": "Q56X52", "text": "This is Ubiquinol oxidase 4, chloroplastic/chromoplastic protein, from Mouse-ear cress, contains 351 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q56X52", "organism_name": "Mouse-ear cress", "protein_name": "Ubiquinol oxidase 4, chloroplastic/chromoplastic", "length": 351, "firstPublicDate": "2006-01-10", "FUNCTION": "Acts early in chloroplast biogenesis as a component of a redox chain responsible for phytoene desaturation, Prevents the generation of toxic oxygen radicals and photooxidation of the nascent photosynthetic apparatus, Involved in the differentiation of multiple plastid types, including chloroplasts, amyloplasts, and etioplasts, Might participate in the chloroplast respiratory chain", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the alternative oxidase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAISGISSGTLTISRPLVTLRRSRAAVSYSSSHRLLHHLPLSSRRLLLRNNHRVQATILQDDEEKVVVEESFKAETSTGTEPLEEPNMSSSSTSAFETWIIKLEQGVNVFLTDSVIKILDTLYRDRTYARFFVLETIARVPYFAFMSVLHMYETFGWWRRADYLKVHFAESWNEMHHLLIMEELGGNSWWFDRFLAQHIATFYYFMTVFLYILSPRMAYHFSECVESHAYETYDKFLKASGEELKNMPAPDIAVKYYTGGDLYLFDEFQTSRTPNTRRPVIENLYDVFVNIRDDEAEHCKTMRACQTLGSLRSPHSILEDDDTEEESGCVVPEEAHCEGIVDCLKKSITS", "length": 351, "molWeight": 40574, "crc64": "D8A38C9A4EC0EF69", "md5": "F4231B63E42AE3085FBB10E8EABA7713"}}
{"primaryAccession": "Q582G4", "text": "This is Protein arginine N-methyltransferase 7 protein, from Trypanosoma brucei brucei (strain 927/4 GUTat10.1), contains 390 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q582G4", "organism_name": "Trypanosoma brucei brucei (strain 927/4 GUTat10.1)", "protein_name": "Protein arginine N-methyltransferase 7", "length": 390, "firstPublicDate": "2009-05-05", "FUNCTION": "Arginine methyltransferase that specifically catalyzes the formation of omega-N monomethylarginine (MMA), Has activity toward multiple substrates in vitro, Able to mediate the arginine methylation of histones and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family, PRMT7 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPPKQHRHQKKDKNDNALQNTIGFVPPGATLASVSGYRPPDAFVNRIDRNIPVPARLRHTPVSLIEAVNDFHYAMMNDEERNNFYYEVLKKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELKSKHLPEPPDVLLSEIFGTMMLGESALDYVVDVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAKHYGIRMNSVNFRRLSDPIELFRVDFSSSNRNDIPRRKHFDVVAKESGTAHAMLFYWKVTDDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLPTPVVFTEGKNYNFECNFSGDRVILHMQLCPESGNGEMTECEGKTT", "length": 390, "molWeight": 44026, "crc64": "32C2C7EEF1EB45B1", "md5": "12169DA58482670D1602E2F48E505660"}}
{"primaryAccession": "Q58A45", "text": "This is PAN2-PAN3 deadenylation complex subunit PAN3 protein, from Human, contains 887 amino acids, has 1 C3H1-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [43, 71], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "Q58A45", "organism_name": "Human", "protein_name": "PAN2-PAN3 deadenylation complex subunit PAN3", "length": 887, "firstPublicDate": "2007-03-20", "FUNCTION": "Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover, PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP), PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex, Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1, PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, PAN3 family", "domain_description": {"C3H1-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNSGGGLPPPSAAASPSSSSLAAAVAVVAPPGVGGVPGGAAVGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLALAGAPVAGFPPGAVAGGGAGPPPGPKKPDLGDPGTGAAAGGGGSSGGLDGPRLAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKYPLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSKARKAKNPIGCLADRCKSGVPINMVWWNRVTENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPGMSLSAGSSPLHSPKITPHTSPAPRRRSHTPNPASYMVPSSASTSVNNPVSQTPSSGQVIQKETVGGTTYFYTDTTPAPLTGMVFPNYHIYPPTAPHVAYMQPKANAPSFFMADELRQELINRHLITMAQIDQADMPAVPTEVDSYHSLFPLEPLPPPNRIQKSSNFGYITSCYKAVNSKDDLPYCLRRIHGFRLVNTKCMVLVDMWKKIQHSNIVTLREVFTTKAFAEPSLVFAYDFHAGGETMMSRHFNDPNADAYFTKRKWGQHEGPLPRQHAGLLPESLIWAYIVQLSSALRTIHTAGLACRVMDPTKILITGKTRLRVNCVGVFDVLTFDNSQNNNPLALMAQYQQADLISLGKVVLALACNSLAGIQRENLQKAMELVTINYSSDLKNLILYLLTDQNRMRSVNDIMPMIGARFYTQLDAAQMRNDVIEEDLAKEVQNGRLFRLLAKLGTINERPEFQKDPTWSETGDRYLLKLFRDHLFHQVTEAGAPWIDLSHIISCLNKLDAGVPEKISLISRDEKSVLVVTYSDLKRCFENTFQELIAAANGQL", "length": 887, "molWeight": 95613, "crc64": "4883F859D2A642D2", "md5": "EB2E465E479A6471E3F24473439453F1"}}
{"primaryAccession": "Q58FA4", "text": "This is Transcription factor E2F8 protein, from Mouse, contains 860 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q58FA4", "organism_name": "Mouse", "protein_name": "Transcription factor E2F8", "length": 860, "firstPublicDate": "2007-08-21", "FUNCTION": "Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells, Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3', Directly represses transcription of classical E2F transcription factors such as E2F1: component of a feedback loop in S phase by repressing the expression of E2F1, thereby preventing p53/TP53-dependent apoptosis, Plays a key role in polyploidization of cells in placenta and liver by regulating the endocycle, probably by repressing genes promoting cytokinesis and antagonizing action of classical E2F proteins (E2F1, E2F2 and/or E2F3), Required for placental development by promoting polyploidization of trophoblast giant cells, Acts as a promoter of sprouting angiogenesis, possibly by acting as a transcription activator: associates with HIF1A, recognizes and binds the VEGFA promoter, which is different from canonical E2 recognition site, and activates expression of the VEGFA gene", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the E2F/DP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MENQKENLFSEPHKRGLMKSPLHPSSKANMVLAEIQPDLGPLTTPTKPKEVSQGEPWTPTANLKMLISAVSPEIRSRDQKRGLSDNRSALPEARDCLHEHLSGDEFEKSQPSRKEKSLGLLCHKFLARYPKYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLTKTLGTLKSVGEENKYAEQIMMIKRKEYEQEFDFIKSCGIEDHVIKSHTGQNGHSDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEIAAKILIGEDHVEDLDKSKYKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNNSGSSPIMPLPASLEAEQSAKENCAKNLFSTRGKPSFTRHPSLIKLVKSIENDRRKISSAPSSPVKSNKAESSQNSPPVPNKMAQLAAICKMQLEEQSSEPRKKVKVNLARSGHYKPLAPLDPTVNTELELLTPSLIQPLGVVPLIPSPLSSAVPVILPQAPSGPSYAIYLQPAQAQMLTPPPGLSPTVCPTQPSNATGSKDPTDAPAEKTATDAATTGSLQPAPERHGAKHRSKETTGDRGTKRMITAEDSGPSSVKKPKEDLKALENVPTPTPLFPSGYLIPLTQCSSLGPDSVLSNTENSGTPSPNHRIYGSPIAGVIPVASSELTAVNFPPFHVTPLKLMVSPTSMAAVPVGNSPALNSGHPAPAQNPSSAIVNFTLQHLGLISPGVQMSASPGPGAGTVPVSPRVEADNLSSRQRRATNHDSPVLGQSQLNGQPVAGTGAQQPVPVTPKGSQLVAENFFRTPGGPTKPTSSPYTDFDGANKTSFGTLFVPQRKLEVSTEDIH", "length": 860, "molWeight": 93276, "crc64": "792E3DDCA299ACE7", "md5": "A62E054E6B28C935932C90C79CB9476A"}}
{"primaryAccession": "Q58WW2", "text": "This is DDB1- and CUL4-associated factor 6 protein, from Human, contains 860 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q58WW2", "organism_name": "Human", "protein_name": "DDB1- and CUL4-associated factor 6", "length": 860, "firstPublicDate": "2007-09-11", "FUNCTION": "Ligand-dependent coactivator of nuclear receptors, Enhance transcriptional activity of the nuclear receptors NR3C1 and AR, May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRGGSYPHLLWDVRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDDTKLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTRIKTSCTKEDCKDDILINCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGMVARFIPSHLNNKSCRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDTARELKTPSAEERREELRQPPVKRLRLRGDWSDTGPRARPESERERDGEQSPNVSLMQRMSDMLSRWFEEASEVAQSNRGRGRSRPRGGTSQSDISTLPTVPSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEETSTRDSALQDTDDSDDDPVLIPGARYRAGPGDRRSAVARIQEFFRRRKERKEMEELDTLNIRRPLVKMVYKGHRNSRTMIKEANFWGANFVMSGSDCGHIFIWDRHTAEHLMLLEADNHVVNCLQPHPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLRMLASLNHIRADRLEGDRSEGSGQENENEDEE", "length": 860, "molWeight": 96292, "crc64": "8C7602D635DAF124", "md5": "0607FEF3D12C42A33B07C9AC0342DBCC"}}
{"primaryAccession": "Q59E36", "text": "This is REST corepressor protein, from Fruit fly, contains 590 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q59E36", "organism_name": "Fruit fly", "protein_name": "REST corepressor", "length": 590, "firstPublicDate": "2006-03-07", "FUNCTION": "Essential component of a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells, The BHC complex is recruited by Ttk88 and probably acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier, May serve as a molecular beacon for the recruitment of molecular machinery that imposes silencing across a chromosomal interval", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CoREST family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVLAERNTTDVVRNGRRSRGPSPNTHTTGGVTNSASLVGSGNNSGHSGNANANEKTTTAVPGAGTPESSDDDNSTKRNGKSKAKQSEYEEKIRVGRDYQAVCPPLVPEAERRPEQMNERALLVWSPTKEIPDLKLEEYISVAKEKYGYNGEQALGMLFWHKHDLERAVMDLANFTPFPDEWTIEDKVLFEQAFQFHGKSFHRIRQMLPDKSIASLVKYYYSWKKTRHRSSAMDRQEKAIKAVVKDGSENGSEVGSNEESDNDDKIQKNRQVMEQLDKECETINVDDVLSKPAAANTESAQPRISARWLPDEIQVALLAIREYGKNFPTIAKVVATKTEAHVRTFYLNNRRRYNLDQIVKEYEAGKSEESGAEEQTEPAVDAAAAGAATASAPSAADSTSAASATADRKQSTENSNNGVETMQESLPKKEDPKKPELAAAVLKIGVAEAADAVATVASSTASGVIGAATSASKPSTSATITIIDESDTATNSSSDVVTTGLATSTGSSALSSTTSAPASKTQTSSEELSAQKSNPASGIAAIGAATGGGQTANSSGSKRDSSVLPVAEQPPAKKIALSTGGGSSVAEFLAN", "length": 590, "molWeight": 62696, "crc64": "17B010081DB57AD7", "md5": "7A0E13F72D5E9A171552265CDB90DA19"}}
{"primaryAccession": "Q59SF7", "text": "This is Cell wall mannoprotein PIR1 protein, from Yeast, contains 385 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q59SF7", "organism_name": "Yeast", "protein_name": "Cell wall mannoprotein PIR1", "length": 385, "firstPublicDate": "2014-04-16", "FUNCTION": "Component of the outer cell wall layer required for stability of the cell wall and specifically for cell wall rigidity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the PIR protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKYSTLVSIAAFISTSLAATVPDEHYSTLSPSAKIPSGASTDFSGTFGIQVVTVESASALSTDTATSTLTRNDNKKEATPVAQITDGQVQHQTTGGVSAIKQISDGQVQHQTNAAQPIAQISDGQIQHQTTAKATATPVQQINDGQIQHQTTVQPVAQISDGQIQHQTAKATATPVQQIGDGQIQHQTTVQPVAQISDGQIQHQTVKASATPVQQIGDGQIQHQTTAAAATTASAVKQINDGQIQHQTTTAENVAKAQSDGQAIATGSPSSNSTLSDDDDLSSTIPKACSSANNLEMTLHDSVLKDTHERWGAIVANHQFQFDGPIPQAGTIYSAGWSIKDGYLYLGDSNIFYQCLSGDFYNLYDENVAKQCSAVKLSVIEFVNC", "length": 385, "molWeight": 40621, "crc64": "2A24722AFC101884", "md5": "F5B852BA16F4A0534CAF631FCF6BA161"}}
{"primaryAccession": "Q59WG7", "text": "This is Protein BIG1 protein, from Yeast, contains 322 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q59WG7", "organism_name": "Yeast", "protein_name": "Protein BIG1", "length": 322, "firstPublicDate": "2007-02-20", "FUNCTION": "Required for normal beta-1,6-glucan synthesis, for hyphal morphogenesis, adhesion and virulence", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the BIG1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRLFVLLAYIIPFILCQLTPVLVASHKLVRGLKEEINPSNTLPHNVTSVTNMLKKLITECSSDAYLLINQPGLTYADLTTEKKDNWPFLRNYLYMSSTIVGLPRVENPIDLDFLEQYIISNCDAETINVWHDSEDEVVDYYDIRKRVIRIDLSPLSISNHDDRVKEIFEHDQLIRKILRKLPSAHYTIILTSLEPGIIHPVPRFLMEETPASFEIFDDIINDPFHNREIEKNDRFHKVEPNWNPIRDSNDRYYRNKKKDEIHLFDYELWEKNEKLITTIFVMVLSLFMMKIISFFNYLKQKIIQKKQQKSKRGIIADDKKLD", "length": 322, "molWeight": 38099, "crc64": "A5ED46A402EEB3DC", "md5": "2C8661F88ACA78C68DEA21EB82AEAEB9"}}
{"primaryAccession": "Q5A960", "text": "This is Histone deacetylase HDA1 protein, from Yeast, contains 833 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5A960", "organism_name": "Yeast", "protein_name": "Histone deacetylase HDA1", "length": 833, "firstPublicDate": "2013-06-26", "FUNCTION": "Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events, Histone deacetylases act via the formation of large multiprotein complexes, Deacetylates the YNG2 subunit of NuA4 histone acetyltransferase (HAT) module, leading to the reduction of YNG2 and NuA4 HAT at the promoters of hypha-specific genes, Plays a key role in the regulation of filamentous growth and virulence, Involved in the switch between two heritable states, the white and opaque states, These two cell types differ in many characteristics, including cell structure, mating competence, and virulence, Each state is heritable for many generations, and switching between states occurs stochastically at low frequency", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone deacetylase family, HD type 2 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSTGQEEHLDSKLENQISEEENQSQNQNFPTAIEDSIQASIEKLDEVDDEINPIEVKDEFPTTIGTTYDILHPREPFPKRIKLEETETEPDSNGIADNDQTMVVVPPKKPQLFYTPLKTGLVYDVRMRYHAKVFTSYSEYIDPHPEDPRRIYRIYKKLVEAGIVLDPSLAGINEIGPFMLKIPIREATSEEILQVHSEDHLKFIQSTEDMSRDQLLKETETGDSIYVNNDSYLSAKLSCGGTIEACKAVIEGRVKNSLAIVRPPGHHAEPNTPAGFCLFSNVAVAAKNMLKNYPESVRRIVIVDWDIHHGNGTQKAFYNDPRVLYISLHRFENGKFYPGTKYGDLNQVGEGPGEGFTINIPWRSSGMHDGDYVYAFNKIIQPVISEFDPDLIIVSSGFDAADGDVIGACHVTPAGYGYMTHTLKGIARGKLAVILEGGYNLDSISKSALAVAKVLVGEPPENTITLRPQAEAIEVVDEVIKIQSKYFKSLRNGIPNGIFEDVYDLADVEKSNYKLVNIADPIRSHQVEKLFNEKEFINIPIISSPSNGEKPPFTTDLPDQLEDLIVASPDIYNCTTIILTIHDPPEIWANINPTNGVIETNSTMVLEHPLVQIMDKIQKEKDPENQEKFGYLDINIPSFQLPIPGTTSESSTYNPIIFAQEVLLYIWDNYIAYFQQLKNLVMVGFGDSYQSIVNLYGKRPSNEIKDLIKGTVAFLNRTTLKPLIPVMDESMVDWYYQNSIIFTSNFNTCWTGGSGAGNGNGNGNGNNGNSSNGGGNKSADSNGHDDFSKRPRKKFGRVIKAKTDGLCDVIQEKFDEGVDFILDSIEDYSSSED", "length": 833, "molWeight": 92913, "crc64": "AB2ACF03720A926F", "md5": "3E4047F5B39FCF97E77DD8A20CAC1AB5"}}
{"primaryAccession": "Q5ABZ2", "text": "This is Transcription factor RBF1 protein, from Yeast, contains 534 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5ABZ2", "organism_name": "Yeast", "protein_name": "Transcription factor RBF1", "length": 534, "firstPublicDate": "2014-03-19", "FUNCTION": "Transcriptional activator that binds to the RPG box and to telomeres, Involved in the regulation of the transition between yeast and filamentous forms and plays a role in virulence, Induces expression of HWP1, a major hyphal cell protein and virulence factor", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RBF1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSNKNQSDLNIPTNSASLKQKQRQQLGIKSEIGASTSDVYDPQVASYLSAGDSPSQFANTALHHSNSVSYSASAAAAAAELQHRAELQRRQQQLQQQELQHQQEQLQQYRQAQAQAQAQAQAQAQAQREHQQLQHAYQQQQQLHQLGQLSQQLAQPHLSQHEHVRDALTTDEFDTNEDLRSRYIENEIVKTFNSKAELVHFVKNELGPEERCKIVINSSKPKAVYFQCERSGSFRTTVKDATKRQRIAYTKRNKCAYRLVANLYPNEKDQKRKNKPDEPGHNEENSRISEMWVLRMINPQHNHAPDPINKKKRQKTSRTLVEKPINKPHHHHLLQQEQQQQQQQQQQQQQQQQQQQQQQHNANSQAQQQAAQLQQQMQQQLQASGLPTTPNYSELLGQLGQLSQQQSQQQQLHHIPQQRQRTQSQQSQQQPQQTPHGLDQPDAAVIAAIEASAAAAVASQGSPNVTAAAVAALQHTQGNEHDAQQQQDRGGNNGGAIDSNVDPSLDPNVDPNVQAHDHSHGLRNSYGKRSGFL", "length": 534, "molWeight": 60280, "crc64": "BA7AD268BDE052C8", "md5": "3E3117B0CB7398E5AF0A68766AD5E990"}}
{"primaryAccession": "Q5CPU3", "text": "This is Diamine acetyltransferase protein, from Cryptosporidium parvum (strain Iowa II), contains 152 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5CPU3", "organism_name": "Cryptosporidium parvum (strain Iowa II)", "protein_name": "Diamine acetyltransferase", "length": 152, "firstPublicDate": "2014-09-03", "FUNCTION": "Enzyme which catalyzes the acetylation of polyamines, Displays higher substrate specificity for spermine than for spermidine, May function to acetylate host-derived polyamines, thus alleviating the necessity for de novo synthesis of these molecules", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the acetyltransferase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MISSFEVRKATIDDYFELRNLICDVTRCTETLSREQAEERFRYNTYHPYCLVDTENGRIVGYAGFYIIPHLGRKNDSRIEHVIISKEYRNRGLGRLLCKQIIEDAKNKFNCGRIDLTVESHIAKKLYSSLEFEKVNTEVMRNSFLDLTPKSD", "length": 152, "molWeight": 17837, "crc64": "93DC5867C9B654B2", "md5": "436299DF8EC76BC4CC8BAFA78396D751"}}
{"primaryAccession": "Q5EU90", "text": "This is Trans-2-enoyl-CoA reductase protein, from Euglena gracilis, contains 539 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5EU90", "organism_name": "Euglena gracilis", "protein_name": "Trans-2-enoyl-CoA reductase", "length": 539, "firstPublicDate": "2005-03-29", "FUNCTION": "Catalyzes reduction of trans-2-enoyl-CoA to acyl-CoA, an important step in the fatty acid biosynthesis pathway, which is performed in mitochondria under anaerobiosis, Preferably catalyzes the reduction of short chain length substrates such as crotonyl-CoA ((2E)-butenoyl-CoA) and (2E)-hexenoyl-CoA, Can use both NADH and NADPH as electron donor, with 2-3-fold higher specific activities for NADH relative to NADPH, Originally thought to contribute to wax ester production under anaerobic conditions (PubMed:15569691), Later shown to be dispensable for wax ester production under anaerobic conditions, but involved in the greening process (chlorophyll synthesis and/or chloroplast development) (PubMed:30650145)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the TER reductase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSCPASPSAAVVSAGALCLCVATVLLATGSNPTALSTASTRSPTSLVRGVDRGLMRPTTAAALTTMREVPQMAEGFSGEATSAWAAAGPQWAAPLVAAASSALALWWWAARRSVRRPLAALAELPTAVTHLAPPMAMFTTTAKVIQPKIRGFICTTTHPIGCEKRVQEEIAYARAHPPTSPGPKRVLVIGCSTGYGLSTRITAAFGYQAATLGVFLAGPPTKGRPAAAGWYNTVAFEKAALEAGLYARSLNGDAFDSTTKARTVEAIKRDLGTVDLVVYSIAAPKRTDPATGVLHKACLKPIGATYTNRTVNTDKAEVTDVSIEPASPEEIADTVKVMGGEDWELWIQALSEAGVLAEGAKTVAYSYIGPEMTWPVYWSGTIGEAKKDVEKAAKRITQQYGCPAYPVVAKALVTQASSAIPVVPLYICLLYRVMKEKGTHEGCIEQMVRLLTTKLYPENGAPIVDEAGRVRVDDWEMAEDVQQAVKDLWSQVSTANLKDISDFAGYQTEFLRLFGFGIDGVDYDQPVDVEADLPSAAQQ", "length": 539, "molWeight": 57303, "crc64": "A52C244AC61E2CDF", "md5": "875DE1B0B84005B09CC39DF96259A0C7"}}
{"primaryAccession": "Q5FW60", "text": "This is Major urinary protein 20 protein, from Mouse, contains 181 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5FW60", "organism_name": "Mouse", "protein_name": "Major urinary protein 20", "length": 181, "firstPublicDate": "2010-10-05", "FUNCTION": "Male pheromone which stimulates female sexual attraction to male urinary scent and promotes a strong learned attraction to the airborne urinary odor of an individual male (PubMed:20525243, PubMed:31996852), Promotes spatial learning by rapidly conditioning preference for its remembered location among females and competitor males so that animals prefer to spend time in the site even when scent is absent (PubMed:23239735), In addition to promoting a rapid attraction response, also elicits ultrasonic vocalizations and urinary scent marking in females which do not occur immediately after exposure (PubMed:31996852), Stimulates hippocampal neurogenesis and cell proliferation in the subventricular zone in females (PubMed:25972792), Promotes male aggressive behavior (PubMed:18064011), Response to Mup20 is mediated by a neural circuit extending from the accessory olfactory bulb to a subset of nitric oxidase synthase-expressing neurons in the medial amygdala (PubMed:31996852), As well as acting as a pheromone itself, binds most of the male pheromone, 2-sec-butyl-4,5-dihydrothiazole, in urine and is responsible for its slow release from scent marks (PubMed:15934926, PubMed:25279835)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the calycin superfamily, Lipocalin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLLVLLLCLGLTLVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE", "length": 181, "molWeight": 20930, "crc64": "CBAF1D33E1B03074", "md5": "384655C0000E9F7E3086C3984D2270C3"}}
{"primaryAccession": "Q5FW85", "text": "This is Extracellular matrix protein 2 protein, from Mouse, contains 670 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5FW85", "organism_name": "Mouse", "protein_name": "Extracellular matrix protein 2", "length": 670, "firstPublicDate": "2007-05-15", "FUNCTION": "Promotes matrix assembly and cell adhesiveness", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the small leucine-rich proteoglycan (SLRP) family, SLRP class I subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLAVLFCFILLIVLQTDCERGTRRQRRRMHQRRLRKSSSFHLRANRQLEVQQTTAAPDARLPTANSDYSVEENIESLLSNLGVESSYSVLPGKKGYCFVKGMIMYNKAVWSPEPCTTCLCSNGRVLCDETECHPKACPYTIKPEGECCPICSDAEQESINKLHKQVPPPQMEMDQVAIKEALQSEEDEEIAEGHKEHKKETSVPTKIHGDGERTERKLRPEKEGRSAHQPLYHGRREEEESKEETEREGEEEEEEEEEEEEDAIRGDVFRMSSRVIPGTPRGRPRLPRSCSLSYRTISCVHADFTEIPPITAPEVTNLELVGNSIISIPDEAFNGLPNLERLDLSRNNITSSGIGPKAFKSLKKLMRLNMDGNNLVHIPSDLPSTLEELKINDNNLQAIDEKSLSDLNQLVTLELEGNNLSEINVDPLAFQSLESLSYLRLGRNKFRIIPQGLPASTEELYLENNQIEEITEICFNHTRKITMIILRYNKIEESRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLIGNQIDRIPGYVFGHMQPGLEYLYLSFNRLSDDGVDLVSFYGAYHSLRELFLDHNDFKSIPPGIQDMKALHFLRLNNNKIRNIHPEQICNAEEDEDSALEHLHLENNYIRTREISSYAFSCIRLYSSIVLKPQHIK", "length": 670, "molWeight": 76676, "crc64": "025BE9522417F5E3", "md5": "0905D234B47C4AC0F3D85DAA611366AA"}}
{"primaryAccession": "Q5FWF5", "text": "This is N-acetyltransferase ESCO1 protein, from Human, contains 840 amino acids, has 1 CCHH-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [617, 641], "description": "CCHH-type", "keyword_description": "Zinc finger", "textural_description": "CCHH-type Zinc finger"}], "meta_data": {"primaryAccession": "Q5FWF5", "organism_name": "Human", "protein_name": "N-acetyltransferase ESCO1", "length": 840, "firstPublicDate": "2005-06-07", "FUNCTION": "Acetyltransferase required for the establishment of sister chromatid cohesion (PubMed:15958495, PubMed:18614053), Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together, In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase, Acts by mediating the acetylation of cohesin component SMC3 (PubMed:18614053)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the acetyltransferase family, ECO subfamily", "domain_description": {"CCHH-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST", "length": 840, "molWeight": 94983, "crc64": "A36BE0EC1BE3EDF2", "md5": "4A419D4C2BDAC6A9ED4F01A41202B459"}}
{"primaryAccession": "Q5FWY4", "text": "This is Maternal DNA replication licensing factor mcm6 protein, from African clawed frog, contains 821 amino acids, has 1 C4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [160, 187], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "Q5FWY4", "organism_name": "African clawed frog", "protein_name": "Maternal DNA replication licensing factor mcm6", "length": 821, "firstPublicDate": "2006-05-16", "FUNCTION": "Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells, The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit, The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity, The existence of maternal and zygotic forms of mcm3 and mcm6 suggests that specific forms of mcm2-7 complexes may be used during different stages of development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCM family", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MELGGPAAAGDTDIAGQQLFKDELSDKCQKLFLEFLEECKGKDGSNLYVSAAEELIRPERNTLAVNFTDIEYYNQQLATTIQEEYYRVYPHLCRAVRSFARQMGNIPANKEFYIAFSDFPARQKIRELSSAKIGTLLRISGQVVRTHPVHPELVSGTFLCMDCQSIVKDVEQQFRYTQPTICKNPVCANRRRFTLDTNKSRFVDFQKVRIQETQAELPRGAIPRSVEIILRAEAVESAMAGDRCDFTGTLIVVPDVSALAAGDARMETGAKVTGGEGFNSEGVQGLKALGVRDLSYRLAFLACYVGATNPRFGGKDLREEDQTAESIKNQMTVQEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEIKRGVLLMLFGGVPKTTMEGTSLRGDINVCIVGDPSTSKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVKDEESHEFVIEAGALMLADNGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVGGRYERSKSLKHNVNLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHARNEESIERVYSIEDIQRYLLFARQFQPKITKEAEEFIVEQYRRLRQRDGSGVAKSSWRITVRQLESLIRLSESMARMHCSDEVQPKHVKEAFRLLSKSIIRVDTPDVSFDQGEDEKNIEGENNGNLNNGEEAMETNQDEPINEKPSSNAGLKMSFAEYKQISNLLVLYMQKMEETEEECHLTTTDLVNWYLKEMEAEIETETELILKKRLIEKVIHRLIYYDHILIELNKSELKTMDDTKETGEDAAEDRILVVNPNYMLED", "length": 821, "molWeight": 92639, "crc64": "68916B7363974731", "md5": "5DA1A8AC8B95FF1B1A8C449BC25846E2"}}
{"primaryAccession": "Q5HYJ3", "text": "This is Protein FAM76B protein, from Human, contains 339 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5HYJ3", "organism_name": "Human", "protein_name": "Protein FAM76B", "length": 339, "firstPublicDate": "2006-07-11", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the FAM76 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAASALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHPKHHHHHHHHHHRHSSSHHKISNLSPEEEQGLWKQSHKSSATIQNETPKKKPKLESKPSNGDSSSINQSADSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHKETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP", "length": 339, "molWeight": 38708, "crc64": "4ED7FEE05F23790C", "md5": "414050760AD89D20AE533E952D0F2E8A"}}
{"primaryAccession": "Q5HZG4", "text": "This is Transcription initiation factor TFIID subunit 3 protein, from Mouse, contains 932 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [867, 917], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "Q5HZG4", "organism_name": "Mouse", "protein_name": "Transcription initiation factor TFIID subunit 3", "length": 932, "firstPublicDate": "2006-07-11", "FUNCTION": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (By similarity), TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (By similarity), The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (By similarity), The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C (By similarity), TAF3 forms the TFIID-A module together with TAF5 and TBP (By similarity), Required in complex with TBPL2 for the differentiation of myoblasts into myocytes (PubMed:17704303), The TAF3-TBPL2 complex replaces TFIID at specific promoters at an early stage in the differentiation process (PubMed:17704303)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TAF3 family", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVNLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKDYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDEMEEEEVINDENFLGKRPLDSPEVEEMPSMKRPRLLSTKGDSLDVVLLEAREPLSSINPQKTPPVLSPVRVQDRADLAPPSPQPPMLAPFAKSQLPIAKPLETKSFTPKTKTKASSPGQKTKSPKAALSPARLGSPIRSPKTIPKEKKSPGRSKSPKSPKSPKIVAHVPQTPVRPETPNRTPSAMVVEKTVKETIPVMKPTQTPPEVVKLNIEMQPKKPVVTDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGDTFTSPKRISGSECATPKASTSSNNFTKSLATPLPLSSGTSSSDNSWTMDASIDEVVRKAKLGAPSNMPPTFPYISSPSISPPTPEPLHKGYEEKAKLPSSVDVKKKLKKELKTKLKKKEKQRDRERERERNKERSKEKDKMREREKEKEAGKELKYPWRELMKDEDSDPYKFKIKEFEDIDAAKVRLKDGIVRREREKHKDKKKDRERSKREKDKRERERLKEKNREDKIKAPPTQLVLPPKEMALPLFSPSAVRVPAMLPAFSPMLPEKLFEEKEKPKEKERKKDKKEKKKKKEKEKEKEKKEREREKERREREKREKEKEKHKHEKIKVEPVIPAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSLNRPKTPPPAPVPIPVRVSPTPLQPPLLTQAAVCPALMPSPAPALSGIGSAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMAAPPEEMQWFCPKCANKIKKDKKHKKRKHRAH", "length": 932, "molWeight": 105115, "crc64": "8061D8E599A650EE", "md5": "46641CBF6D8C02FA7045EE56C0F29263"}}
{"primaryAccession": "Q5JTZ9", "text": "This is Alanine--tRNA ligase, mitochondrial protein, from Human, contains 985 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5JTZ9", "organism_name": "Human", "protein_name": "Alanine--tRNA ligase, mitochondrial", "length": 985, "firstPublicDate": "2006-10-03", "FUNCTION": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala), Also edits incorrectly charged tRNA(Ala) via its editing domain", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the class-II aminoacyl-tRNA synthetase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAASVAAAARRLRRAIRRSPAWRGLSHRPLSSEPPAAKASAVRAAFLNFFRDRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVANSQKCVRAGGHHNDLEDVGRDLSHHTFFEMLGNWAFGGEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDPKAGLDPDLETRDIWLSLGVPASRVLSFGPQENFWEMGDTGPCGPCTEIHYDLAGGVGAPQLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGLERLVAVLQGKHSTYDTDLFSPLLNAIQQGCRAPPYLGRVGVADEGRTDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRRILRRAVRFSMEILKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLRTLGPSDMFPAEVAWSLSLCGDLGLPLDMVELMLEEKGVQLDSAGLERLAQEEAQHRARQAEPVQKQGLWLDVHALGELQRQGVPPTDDSPKYNYSLRPSGSYEFGTCEAQVLQLYTEDGTAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVRAGQEDVLFPVARAQVCGGFILHEAVAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQTPLTPEQLRAVENTVQEAVGQDEAVYMEEVPLALTAQVPGLRSLDEVYPDPVRVVSVGVPVAHALDPASQAALQTSVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRLLAVTGEQAQQARELGQSLAQEVKAATERLSLGSRDVAEALRLSKDIGRLIEAVETAVMPQWQRRELLATVKMLQRRANTAIRKLQMGQAAKKTQELLERHSKGPLIVDTVSAESLSVLVKVVRQLCEQAPSTSVLLLSPQPMGKVLCACQVAQGAMPTFTAEAWALAVCSHMGGKAWGSRVVAQGTGSTTDLEAALSIAQTYALSQL", "length": 985, "molWeight": 107340, "crc64": "721368BD05474F86", "md5": "A1A854388733E00CD27C0BB1EB41BAB0"}}
{"primaryAccession": "Q5JVL4", "text": "This is EF-hand domain-containing protein 1 protein, from Human, contains 640 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5JVL4", "organism_name": "Human", "protein_name": "EF-hand domain-containing protein 1", "length": 640, "firstPublicDate": "2005-10-25", "FUNCTION": "Microtubule-associated protein which regulates cell division and neuronal migration during cortical development, Necessary for mitotic spindle organization (PubMed:19734894, PubMed:28370826), Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration (PubMed:22926142), May enhance calcium influx through CACNA1E and stimulate programmed cell death (PubMed:15258581), Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVSNPVHGLPFLPGTSFKDSTKTAFHRSQTLSYRNGYAIVRRPTVGIGGDRLQFNQLSQAELDELASKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIRQVNIYYYLEDDSMSVIEPVVENSGILQGKLIKRQRLAKNDRGDHYHWKDLNRGINITIYGKTFRVVDCDQFTQVFLESQGIELNPPEKMALDPYTELRKQPLRKYVTPSDFDQLKQFLTFDKQVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGRDPFPLLMNRQRVPKVLVENAKNFPQCVLEISDQEVLEWYTAKDFIVGKSLTILGRTFFIYDCDPFTRRYYKEKFGITDLPRIDVSKREPPPVKQELPPYNGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDNKVLRYLAVLESPIPEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTVDNPVYYGPSDFFIGAVIEVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREAPAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAFSN", "length": 640, "molWeight": 73990, "crc64": "08F9E8BFEC42FCF3", "md5": "84E5404E73D120A10D4B892B902A675C"}}
{"primaryAccession": "Q5K4E3", "text": "This is Polyserase-2 protein, from Human, contains 855 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5K4E3", "organism_name": "Human", "protein_name": "Polyserase-2", "length": 855, "firstPublicDate": "2005-03-15", "FUNCTION": "Serine protease, Hydrolyzes the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln-Gly-Arg-AMC and, to a lesser extent, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Val-Leu-Lys-AMC, Has a preference for substrates with an Arg instead of a Lys residue in position P1", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MARHLLLPLVMLVISPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQHENASWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGRGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLRPRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGASCWVLGWKEPQDRVPVAAAVSILTQRICDCLYQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQGSRELFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGGSNLCPPELAKASGSPHAVYFLLLLTLLIQS", "length": 855, "molWeight": 91955, "crc64": "D1AF7888311FB871", "md5": "0CD4D4BAD5563DD2EE27A03C5FC5C1E6"}}
{"primaryAccession": "Q5MPP0", "text": "This is Fatty acid 2-hydroxylase protein, from Mouse, contains 372 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5MPP0", "organism_name": "Mouse", "protein_name": "Fatty acid 2-hydroxylase", "length": 372, "firstPublicDate": "2007-12-04", "FUNCTION": "Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis (PubMed:15658937, PubMed:16998236, PubMed:22517924), FA2H is stereospecific for the production of (R)-2-hydroxy fatty acids (PubMed:22517924), Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath (PubMed:15658937, PubMed:18815260), Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier (By similarity), Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis (PubMed:21628453), Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins (PubMed:22517924)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the sterol desaturase family, SCS7 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPAPPPAASFTPAEVQRRLAAGACWVRRGASLYDLTSFVRHHPGGEQLLLARAGQDISADLDGPPHRHSDNARRWLEQYYVGELRADPQDPTENGAVASAETQKTDPALEPQFKVVDWDKDLVDWQKPLLWQVGHLGEKYDEWVHQPVARPIRLFHSDLIEAFSKTVWYSVPIIWVPLVLYLSWSYYRTLTQDNIRLFASLTREYSMMMPESVFIGLFVLGMLFWTFVEYVIHRFLFHMKPPSNSHYLIMLHFVMHGQHHKAPFDGSRLVFPPVPASLVIAFFYVFLRLILPETVGGIIFAGGLLGYVLYDMTHYYLHFGSPHKGSYLYNMKAHHVKHHFEYQKSGFGISTKLWDYFFHTLIPEEAHPKMQ", "length": 372, "molWeight": 42981, "crc64": "8E3311FE6491F088", "md5": "24C437265F92D1C5302F018CBDF9B19F"}}
{"primaryAccession": "Q5RJM1", "text": "This is Polyprenol reductase protein, from Rat, contains 330 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5RJM1", "organism_name": "Rat", "protein_name": "Polyprenol reductase", "length": 330, "firstPublicDate": "2010-10-05", "FUNCTION": "Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol (PubMed:8486680), Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation (PubMed:8486680), Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (PubMed:8486680), Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT) (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the steroid 5-alpha reductase family, Polyprenol reductase subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAGWAGAELSVLNPLRALWLLLAAAFLLALLLQLAPARLLPSCALFQDLIRYGKTKQSGSRRPAVCRAFDVPKRYFSHFYVVSVLWNGSLLWFLSQSLFLGAPFPSWLWALLRTLGVTQFQALGMESKASRIQGKKLALSTFLVLVFLWVHSLRRLFECFYVSVFSNTAIHVVQYCFGLVYYVLVGLTVLSQVPMNDKNVYALGKNLLLQARWFHILGMMMFFWSSAHQYKCHVILSNLRRNKKGVVIHCQHRIPFGDWFEYVSSANYLAELMIYISMAVTFGLHNVTWWLVVTYVFFSQALSAFFNHRFYKSTFVSYPKHRKAFLPFLF", "length": 330, "molWeight": 38092, "crc64": "EC97594D66A76543", "md5": "1DDD11E909B6593F568BCEB9236E6AE4"}}
{"primaryAccession": "Q5SML5", "text": "This is Two-component response regulator ORR22 protein, from Rice, contains 696 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5SML5", "organism_name": "Rice", "protein_name": "Two-component response regulator ORR22", "length": 696, "firstPublicDate": "2015-09-16", "FUNCTION": "Transcriptional activator that binds specific DNA sequence, Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system, Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes, May directly activate some type-A response regulators in response to cytokinins (By similarity), Functions as a response regulator in response to cytokinins (PubMed:22383541)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ARR family, Type-B subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLLGALRMEERKGLMGRERDQFPVGMRVLAVDDDPVCLKVLETLLRRCQYHVTSTNQAITALKLLRENRDMFDLVISDVHMPDMDGFKLLELVGLEMDLPVIMLSVNGETKTVMKGITHGACDYLLKPVRIEELRNIWQHVVRRKFGNRERNNLDFSKECNKPQSADTDHGPYQPTCGSSDQNGRSSRKRKELHGEDDDEGDDNDYQENDEPSAAKKPRVVWSVELHRKFVAAVNQLGIDKAVPKRILELMNVEKLTRENVASHLQKYRLYLKRLGAVASQQASIVAAFGGRDPSFLHIGAFEGLQSYQPFAPSAALPSFNPHGLLTRTSAAAAFGLQELAAPSSTIQTSTGNVTVGHCLEENQQANLAQGLTAAIGQPQLQQNWIHQEGNGLSDVFSGSSLTNTLSSTLQRVPSSSLPPQELLECKQAKVSMPPSIRIPPSSSALLERTLGVSTNLGDSSISQQGALPIDGGFSADRLPLHSSFDGAVATKLDTSLAASQREIGQQGKFSVSMLVSPSDNLALAKNAKTGASSSGSTIILPLDTARHSDYLQFGGASNSLQKMDGQKQDHIQSSNIIWSSMPSTQLPSDTQIHNTQNQRLDSGSFNHNIGAHLADQTNASASILPQMKFDTRISEEKMKQKNTYDLGSSKLQGGFNSSGCNFDGLLNSIIKVEKDDLPFMDNELGCDLFPLGACI", "length": 696, "molWeight": 75950, "crc64": "86F8F72741FA624C", "md5": "D6874D20380D49354E224C4E227A4D86"}}
{"primaryAccession": "Q5SUE7", "text": "This is Adenosine deaminase domain-containing protein 1 protein, from Mouse, contains 619 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5SUE7", "organism_name": "Mouse", "protein_name": "Adenosine deaminase domain-containing protein 1", "length": 619, "firstPublicDate": "2007-11-13", "FUNCTION": "Required for male fertility and normal male germ cell differentiation (PubMed:32665638), Plays a role in spermatogenesis (PubMed:15649457), Binds to RNA but not to DNA (PubMed:15649457)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ADAD family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATAGGSRRAPVPGPRLGLPLAAHLPASLGGEGAKDSVGGEKTSGNNDWFQSSRVPSFAQMLKKNLPVQPSAQTVTLPTGYSSESCSLSNMASKVTQVTGNFPEPLLSKGLSSISNPVLPPKKLPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRVLEPAGPPPIPAEPVVTPEAAYVSKVQYEGRQVQYAKISQLVKETFGQLISNHSQYLKCSSSLAAFIIERAGHHEVVAIGTGEYNYSQCIKPNGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPASNLLTLKQNINLYLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELSLHVAVEGKIYLTVYCSADGVNRVNSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILVGDGNCNDTRGLEIAINQRVDDALTSKLPMFYLVNRPHISLVPTAYPLQINLDHKSLSLNWAQGDNSLEIVDGLNGKITESSPFKSGLSMASRLCKAAMLSRFNLLAKEAKTDDLLEARTYHAAKCMSGPYQEAKALLKAYLQQHGYGSWIVKSPCIEQFSM", "length": 619, "molWeight": 67840, "crc64": "168EC0352B1B70A7", "md5": "F0A8D270A12126D8E0D6DA75D79D111C"}}
{"primaryAccession": "Q5SWZ9", "text": "This is Mitochondrial cardiolipin hydrolase protein, from Mouse, contains 221 amino acids, has 1 C3H1-type; atypical Zinc finger, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [{"location": [44, 75], "description": "C3H1-type; atypical", "keyword_description": "Zinc finger", "textural_description": "C3H1-type; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q5SWZ9", "organism_name": "Mouse", "protein_name": "Mitochondrial cardiolipin hydrolase", "length": 221, "firstPublicDate": "2008-03-18", "FUNCTION": "Presents phospholipase and nuclease activities, depending on the different physiological conditions, Interaction with Mitoguardin (MIGA1 or MIGA2) affects the dimer conformation, facilitating the lipase activity over the nuclease activity, Plays a key role in mitochondrial fusion and fission via its phospholipase activity, In its phospholipase role, it uses the mitochondrial lipid cardiolipin as substrate to generate phosphatidate (PA or 1,2-diacyl-sn-glycero-3-phosphate), a second messenger signaling lipid, Production of PA facilitates Mitofusin-mediated fusion, whereas the cleavage of PA by the Lipin family of phosphatases produces diacylgycerol (DAG) which promotes mitochondrial fission, Both Lipin and DAG regulate mitochondrial dynamics and membrane fusion/fission, important processes for adapting mitochondrial metabolism to changes in cell physiology, Mitochondrial fusion enables cells to cope with the increased nucleotide demand during DNA synthesis (By similarity), Mitochondrial function and dynamics are closely associated with biological processes such as cell growth, proliferation, and differentiation (PubMed:21397848), Mediator of MYC activity, promotes mitochondrial fusion and activates AMPK which in turn inhibits YAP/TAZ, thereby inducing cell growth and proliferation (PubMed:26678338), The endonuclease activity plays a critical role in PIWI-interacting RNA (piRNA) biogenesis during spermatogenesis (PubMed:21397847, PubMed:21397848), Implicated in spermatogenesis and sperm fertility in testicular germ cells, its single strand-specific nuclease activity is critical for the biogenesis/maturation of PIWI-interacting RNA (piRNA) (PubMed:21397847, PubMed:23064230, PubMed:23064227), MOV10L1 selectively binds to piRNA precursors and funnels them to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins (PubMed:25762440), Cleaves either DNA or RNA substrates with similar affinity, producing a 5' phosphate end, in this way it participates in the processing of primary piRNA transcripts, piRNAs provide essential protection against the activity of mobile genetic elements, piRNA-mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation (PubMed:23064230, PubMed:23064227), PA may act as signaling molecule in the recognition/transport of the precursor RNAs of primary piRNAs (PubMed:21397847), Interacts with tesmin in testes, suggesting a role in spermatogenesis via association with its interacting partner (PubMed:33783608)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the phospholipase D family, MitoPLD/Zucchini subfamily", "domain_description": {"C3H1-type; atypical Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGRSSWRLVFAAGAGLALALEALPWLMRWLLAGRRPRREVLFFPSQVTCTEALLQAPGLPPGPSGCPCSLPHSESSLSRLLRALLAARSSLELCLFAFSSPQLGRAVQLLHQRGVRVRVITDCDYMALNGSQIGLLRKAGIQVRHDQDLGYMHHKFAIVDKKVLITGSLNWTTQAIQNNRENVLIMEDTEYVRLFLEEFERIWEEFDPTKYSFFPQKHRGH", "length": 221, "molWeight": 25041, "crc64": "A7A2E813281B924E", "md5": "A292E702A0CD04981C542EFA529E174B"}}
{"primaryAccession": "Q5T7N3", "text": "This is KN motif and ankyrin repeat domain-containing protein 4 protein, from Human, contains 995 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5T7N3", "organism_name": "Human", "protein_name": "KN motif and ankyrin repeat domain-containing protein 4", "length": 995, "firstPublicDate": "2006-06-27", "FUNCTION": "May be involved in the control of cytoskeleton formation by regulating actin polymerization", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEKTDAKDQSSQGDEEKDPPKSHPYSVETPYGFHLDLDFLKYVDDIEKGNTIKRIPIHRRAKQAKFSTLPRNFSLPDSGARPPAAPPLQNWSPVVPREASLGTQEQNQSPPLGNAPQASTSRSEVSYHRKALLAEATRQLEAAEPEDAELTFGSGRPQLLRASSMPATLLHSRASEEPGLSLGPPAPPALPPLQGEGSVCDGTFEPAEGLAGFHSSSPRASTRIPELVQEGAEPPEGVVKVPNHLPLPGPPFSFQNVLVVLEDKEDEHNAREAEVLFTPGSPTPSPPPLPSPIPENELLLEEIELNISEIPPPPPVEVDMRSIGIRVTEESLGLARVDPGSISSLKQQVSALEGELSGRTEELAQVRTALQQQEEEIKAREQRIRELEFTVAQLEGQFHQENAKDTQGQTDVMVNTDPVHGLLTRESCDKGIEVNLLGSMESESWGHRGEENGLLWGPDGHKQGNQSPAERVLLPQLSLPQGPEQVLTSSVHSFLSTELRIEEAGTEQEGGPQGGTRGAGGFLWGSDRKTPPAGREETSSNLPGKEHPGRPPSSPTDATIGQYVKKIQELLQEQWNCLEHGYPELASAIKQPASKLSSIQSQLLSSLNLLLSAYSAQAHPPKEPPASSSSPPVEISPSTSLKSIMKKKDYGFRAGGNGTKKNLQFVGVNGGYETTSSEETSGEDSTPEDLSDSEAEKKCDGPDHKHVKDAHLTCEAGQGIPEGTCHAAQESGPGEEVPHSKAERYKPSEEFLNACRALSQHLPETGTTTDQLLRQSLNTISQEWFRVSSRKSSSPAVVASYLHEVQPHSPHFLKLLVNLADHNGNTALHYSVSHSNFSIVKLLLETGVCNVDHQNKAGYTAVMITPLASAETNEDMAVVWKLLREGNVNIQATQGGQTALMLGVSHDREDMVQALLSCQADVNLQDHDGSSALMVACHHGNVDLVRLLLAHPACDSSLTDKAGRTALSIALKSPTHMEIAGLLRAHAEQGRSLGL", "length": 995, "molWeight": 107342, "crc64": "25379EB22B44C760", "md5": "4C99E83193A505DED93E1F1EA37C231B"}}
{"primaryAccession": "Q5T9A4", "text": "This is ATPase family AAA domain-containing protein 3B protein, from Human, contains 648 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5T9A4", "organism_name": "Human", "protein_name": "ATPase family AAA domain-containing protein 3B", "length": 648, "firstPublicDate": "2005-09-13", "FUNCTION": "May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network, may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the AAA ATPase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSWLFGVNKGPKGEGAGPPPPLPPAQPGAEGGGDRGLGDRPAPKDKWSNFDPTGLERAAKAARELEHSRYAKEALNLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRAQAEERRKTLSEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAMRRATVEREMELRHKNEMLRVETEARARAKAERENADIIREQIRLKASEHRQTVLESIRTAGTLFGEGFRAFVTDRDKVTATVAGLTLLAVGVYSAKNATAVTGRFIEARLGKPSLVRETSRITVLEALRHPIQVSRRLLSRPQDVLEGVVLSPSLEARVRDIAIATRNTKKNRGLYRHILLYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTSRRGLLLFMDEADAFLRKRATEEISKDLRATLNAFLYHMGQHSNKFMLVLASNLPEQFDCAINSRIDVMVHFDLPQQEERERLVRLHFDNCVLKPATEGKRRLKLAQFDYGRKCSEVARLTEGMSGREIAQLAVSWQATAYASKDGVLTEAMMDACVQDAVQQYRQKMRWLKAEGPGRGVEHPLSGVQGETLTSWSLATDPSYPCLAGPCTFRICSWMGTGLCPGPLSPRMSCGGGRPFCPPGHPLL", "length": 648, "molWeight": 72573, "crc64": "5133DB55E3415707", "md5": "5AB087F66CF84DAC5283B035513807C7"}}
{"primaryAccession": "Q5TB30", "text": "This is DEP domain-containing protein 1A protein, from Human, contains 811 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5TB30", "organism_name": "Human", "protein_name": "DEP domain-containing protein 1A", "length": 811, "firstPublicDate": "2007-04-17", "FUNCTION": "May be involved in transcriptional regulation as a transcriptional corepressor, The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYPELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDRSSGIHKIQDDPQSSKFLHLNNLNSFKSTECLLLSLLHREKNKEESDSTERLQISNPGFQERCAKKMQLVNLRNRRVSANDIMGGSCHNLIGLSNMHDLSSNSKPRCCSLEGIVDVPGNSSKEASSVFHQSFPNIEGQNNKLFLESKPKQEFLLNLHSEENIQKPFSAGFKRTSTLTVQDQEELCNGKCKSKQLCRSQSLLLRSSTRRNSYINTPVAEIIMKPNVGQGSTSVQTAMESELGESSATINKRLCKSTIELSENSLLPASSMLTGTQSLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQKEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR", "length": 811, "molWeight": 92960, "crc64": "F694E10FB79AF3B0", "md5": "32491E0E9BE32DB85C913DFA24A24510"}}
{"primaryAccession": "Q5TEU4", "text": "This is Arginine-hydroxylase NDUFAF5, mitochondrial protein, from Human, contains 345 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5TEU4", "organism_name": "Human", "protein_name": "Arginine-hydroxylase NDUFAF5, mitochondrial", "length": 345, "firstPublicDate": "2007-10-23", "FUNCTION": "Arginine hydroxylase involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages (PubMed:18940309, PubMed:27226634), Acts by mediating hydroxylation of 'Arg-111' of NDUFS7 (PubMed:27226634), May also have methyltransferase activity (Probable)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the methyltransferase superfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRPAGLWRLCRRPWAARVPAENLGRREVTSGVSPRGSTSPRTLNIFDRDLKRKQKNWAARQPEPTKFDYLKEEVGSRIADRVYDIPRNFPLALDLGCGRGYIAQYLNKETIGKFFQADIAENALKNSSETEIPTVSVLADEEFLPFKENTFDLVVSSLSLHWVNDLPRALEQIHYILKPDGVFIGAMFGGDTLYELRCSLQLAETEREGGFSPHISPFTAVNDLGHLLGRAGFNTLTVDTDEIQVNYPGMFELMEDLQGMGESNCAWNRKALLHRDTMLAAAAVYREMYRNEDGSVPATYQIYYMIGWKYHESQARPAERGSATVSFGELGKINNLMPPGKKSQ", "length": 345, "molWeight": 38918, "crc64": "96E1D29B91980026", "md5": "05D5DD226E5F693F96889D806DC8DE59"}}
{"primaryAccession": "Q5TGU0", "text": "This is Translocator protein 2 protein, from Human, contains 170 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5TGU0", "organism_name": "Human", "protein_name": "Translocator protein 2", "length": 170, "firstPublicDate": "2007-06-26", "FUNCTION": "Cholesterol-binding protein involved in the redistribution of cholesterol from lipid droplets to the endoplasmic reticulum (PubMed:19729679), Required to meet cholesterol demands during erythropoietic differentiation (PubMed:19729679), May play a role in transport processes at the plasma membrane of erythrocytes, including regulating VDAC-mediated ATP export, and import of the heme precursors protoporphyrin IX and 5-aminolevulinic acid (PubMed:27641616, PubMed:30061676, PubMed:31989647)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the TspO/BZRP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRLQGAIFVLLPHLGPILVWLFTRDHMSGWCEGPRMLSWCPFYKVLLLVQTAIYSVVGYASYLVWKDLGGGLGWPLALPLGLYAVQLTISWTVLVLFFTVHNPGLALLHLLLLYGLVVSTALIWHPINKLAALLLLPYLAWLTVTSALTYHLWRDSLCPVHQPQPTEKSD", "length": 170, "molWeight": 19129, "crc64": "8B705EFA0E2E1ABB", "md5": "6CD054C493D1280B0F685EA26BCBBEFC"}}
{"primaryAccession": "Q5TGZ0", "text": "This is MICOS complex subunit MIC10 protein, from Human, contains 78 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5TGZ0", "organism_name": "Human", "protein_name": "MICOS complex subunit MIC10", "length": 78, "firstPublicDate": "2006-10-03", "FUNCTION": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MICOS complex subunit Mic10 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSESELGRKWDRCLADAVVKIGTGFGLGIVFSLTFFKRRMWPLAFGSGMGLGMAYSNCQHDFQAPYLLHGKYVKEQEQ", "length": 78, "molWeight": 8808, "crc64": "6E4F618F07E969BE", "md5": "FF7B23BF7AA81A7F68E09AE6567865F1"}}
{"primaryAccession": "Q5U4F6", "text": "This is Cytoplasmic dynein 2 intermediate chain 2 protein, from Mouse, contains 537 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5U4F6", "organism_name": "Mouse", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "length": 537, "firstPublicDate": "2006-02-21", "FUNCTION": "Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways, Inhibits the MAP3K7-induced NF-kappa-B activation pathway, Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the dynein light intermediate chain family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAMCASPRPFRRVGSAGAAALAAGGAGGAERRGRPAPLQDETLGVASVPSQWRSVQGIRGETKSCQTAGIATAESSAQARTHADAQVQTEAPEEPAAMAPVSQYDTLRLEAFLRRVEAMVIRELNNNWQSHAFDGYEVNWTEQQQTVSCLHTLVYPLAQGQGLHVTGISWNSTGSVLACAYGRLDDGDWSTLKSYVCTWNLDRQGLNPQQPSVVVEVPSAVMCLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSAATDGKVLLWRGSGAGQLRLTKGFALAVQQLPRSTKLKKPPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLASEVAALTRMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMVKVWQLSTAFTEQGPREVEDLDQLEAEITT", "length": 537, "molWeight": 58174, "crc64": "5F73AA6DB7E536F6", "md5": "285DE619C647885676A010B25930F97E"}}
{"primaryAccession": "Q5U5X0", "text": "This is Complex III assembly factor LYRM7 protein, from Human, contains 104 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5U5X0", "organism_name": "Human", "protein_name": "Complex III assembly factor LYRM7", "length": 104, "firstPublicDate": "2006-10-03", "FUNCTION": "Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex, Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the complex I LYR family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGRAVKVLQLFKTLHRTRQQVFKNDARALEAARIKINEEFKNNKSETSSKKIEELMKIGSDVELLLRTSVIQGIHTDHNTLKLVPRKDLLVENVPYCDAPTQKQ", "length": 104, "molWeight": 11955, "crc64": "D112A2F54EFC7BCD", "md5": "97982CE1D8BC2A0E446B6349A76A09B0"}}
{"primaryAccession": "Q5VT66", "text": "This is Mitochondrial amidoxime-reducing component 1 protein, from Human, contains 337 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5VT66", "organism_name": "Human", "protein_name": "Mitochondrial amidoxime-reducing component 1", "length": 337, "firstPublicDate": "2007-01-23", "FUNCTION": "Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles (PubMed:19053771, PubMed:21029045, PubMed:30397129), As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability (PubMed:19053771), May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis (PubMed:21029045), Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction (PubMed:21029045, PubMed:19053771)", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGAAGSSALARFVLLAQSRPGWLGVAALGLTAVALGAVAWRRAWPTRRRRLLQQVGTVAQLWIYPVKSCKGVPVSEAECTAMGLRSGNLRDRFWLVINQEGNMVTARQEPRLVLISLTCDGDTLTLSAAYTKDLLLPIKTPTTNAVHKCRVHGLEIEGRDCGEATAQWITSFLKSQPYRLVHFEPHMRPRRPHQIADLFRPKDQIAYSDTSPFLILSEASLADLNSRLEKKVKATNFRPNIVISGCDVYAEDSWDELLIGDVELKRVMACSRCILTTVDPDTGVMSRKEPLETLKSYRQCDPSERKLYGKSPLFGQYFVLENPGTIKVGDPVYLLGQ", "length": 337, "molWeight": 37499, "crc64": "F983AB08F3D646C4", "md5": "1262C9DC1AF0749DA7B5EF73FC677DA0"}}
{"primaryAccession": "Q5VTD9", "text": "This is Zinc finger protein Gfi-1b protein, from Human, contains 330 amino acids, has 6 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [163, 186], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [192, 214], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [220, 242], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [248, 270], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [276, 298], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [304, 327], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q5VTD9", "organism_name": "Human", "protein_name": "Zinc finger protein Gfi-1b", "length": 330, "firstPublicDate": "2007-10-02", "FUNCTION": "Essential proto-oncogenic transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages, Component of a RCOR-GFI-KDM1A-HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation, Transcriptional repressor or activator depending on both promoter and cell type context; represses promoter activity of SOCS1 and SOCS3 and thus, may regulate cytokine signaling pathways, Cooperates with GATA1 to repress target gene transcription, such as the apoptosis regulator BCL2L1; GFI1B silencing in leukemic cell lines markedly increase apoptosis rate, Inhibits down-regulation of MYC and MYB as well as the cyclin-dependent kinase inhibitor CDKN1A/P21WAF1 in IL6-treated myelomonocytic cells, Represses expression of GATA3 in T-cell lymphomas and inhibits GATA1-mediated transcription; as GATA1 also mediates erythroid GFI1B transcription, both GATA1 and GFI1B participate in a feedback regulatory pathway controlling the expression of GFI1B gene in erythroid cells, Suppresses GATA1-mediated stimulation of GFI1B promoter through protein interaction, Binds to gamma-satellite DNA and to its own promoter, auto-repressing its own expression, Alters histone methylation by recruiting histone methyltransferase to target genes promoters, Plays a role in heterochromatin formation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 6}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPRSFLVKSKKAHTYHQPRVQEDEPLWPPALTPVPRDQAPSNSPVLSTLFPNQCLDWTNLKREPELEQDQNLARMAPAPEGPIVLSRPQDGDSPLSDSPPFYKPSFSWDTLATTYGHSYRQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSLRYSPGMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHNLK", "length": 330, "molWeight": 37492, "crc64": "947DD9C34B5BD962", "md5": "EDAF3F96D097FC491F71BFD1909AF6A5"}}
{"primaryAccession": "Q5VWG9", "text": "This is Transcription initiation factor TFIID subunit 3 protein, from Human, contains 929 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [865, 915], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "Q5VWG9", "organism_name": "Human", "protein_name": "Transcription initiation factor TFIID subunit 3", "length": 929, "firstPublicDate": "2006-07-11", "FUNCTION": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473), TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473), The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473), The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C (PubMed:33795473), TAF3 forms the TFIID-A module together with TAF5 and TBP (PubMed:33795473), Required in complex with TBPL2 for the differentiation of myoblasts into myocytes (PubMed:11438666), The TAF3-TBPL2 complex replaces TFIID at specific promoters at an early stage in the differentiation process (PubMed:11438666)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TAF3 family", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVSLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEELPAMKRPRLLSTKGDTLDVVLLEAREPLSSINTQKIPPMLSPVHVQDSTDLAPPSPEPPMLAPVAKSQMPTAKPLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTVSKEKKSPGRSKSPKSPKSPKVTTHIPQTPVRPETPNRTPSATLSEKISKETIQVKQIQTPPDAGKLNSENQPKKAVVADKTIEASIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGPECTTPKASTSANNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPNFPYISSPSVSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEPVALAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSQNRPKTPPPAPAPAPGPMLVSPAPVPLPLLAQAAAGPALLPSPGPAASGASAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMTAPPEEMQWFCPKCANKKKDKKHKKRKHRAH", "length": 929, "molWeight": 103582, "crc64": "C951754B5B532E72", "md5": "92CB35CE30ECB36BD65CF88EBD52DC1E"}}
{"primaryAccession": "Q5VWK5", "text": "This is Interleukin-23 receptor protein, from Human, contains 629 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5VWK5", "organism_name": "Human", "protein_name": "Interleukin-23 receptor", "length": 629, "firstPublicDate": "2006-12-12", "FUNCTION": "Associates with IL12RB1 to form the interleukin-23 receptor, Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade, IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues, IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the type I cytokine receptor family, Type 2 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQPRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMNNNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDLNTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSLSNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGIVNEELPSINTYFPQNILESHFNRISLLEK", "length": 629, "molWeight": 71722, "crc64": "AC63C89E81AABF05", "md5": "4406B981C8FFF63DA43F0FA6FC57CF21"}}
{"primaryAccession": "Q5W7F2", "text": "This is ADP-ribosylation factor GTPase-activating protein AGD3 protein, from Mouse-ear cress, contains 827 amino acids, has 1 C4-type Zinc finger, locates in Golgi apparatus.", "functionDomainRange": [{"location": [516, 539], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "Q5W7F2", "organism_name": "Mouse-ear cress", "protein_name": "ADP-ribosylation factor GTPase-activating protein AGD3", "length": 827, "firstPublicDate": "2008-04-29", "FUNCTION": "GTPase-activating protein (GAP) for ADP ribosylation factor (ARF), Involved in the spatial control of provascular differentiation, Required for the formation of the normal pattern of continuous secondary veins, Involved in auxin signaling but not in polar auxin transport or in auxin responses, Required for PIN1 internalization in roots", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MHFTKLDDSPMFRKQLQSMEESAEILRERSLKFYKGCRKYTEGLGEAYDGDIAFASALETFGGGHNDPISVAFGGPVMTKFTIALREIGTYKEVLRSQVEHILNDRLLQFANMDLHEVKEARKRFDKASLTYDQAREKFLSLRKGTKSDVAAALEQELHTSRSMFEQARFNLVTALSNVEAKKRFEFLEAVSGTMDAHLRYFKQGYELLHQMEPYINQVLTYAQQSRERSNYEQAALNEKMQEYKRQVDRESRWGSNGSNGSPNGDGIQAIGRSSHKMIDAVMQSAARGKVQTIRQGYLSKRSSNLRGDWKRRFFVLDSRGMLYYYRKQCSKPSGSGSQLSGQRNSSELGSGLLSRWLSSNNHGHGGVHDEKSVARHTVNLLTSTIKVDADQSDLRFCFRIISPTKNYTLQAESALDQMDWIEKITGVIASLLSSQVPEQRLPGSPMGSGHHRSASESSSYESSEYDHPTTEEFVCERSFLGYNERPSRSFQPQRSIRKGEKPIDALRKVCGNDKCADCGAPEPDWASLNLGVLVCIECSGVHRNLGVHISKVRSLTLDVKVWEPSVISLFQALGNTFANTVWEELLHSRSAIHFDPGLTVSDKSRVMVTGKPSYADMISIKEKYIQAKYAEKLFVRRSRDSDFPQSAAQQMWDAVSGNDKKAVYRLIVNGDADVNYVYDQTSSSSLTLSRVILVPERPKREDVLLRLRNELLDRTGSSSNISPEGSGGSSLLHCACEKADLGMVELLLQYGANVNASDSSGQTPLHCCLLRGKVTIARLLLTRGADPEAMNREGKTALDIAAESNFTDPEVLALLSDTNGYNHRQC", "length": 827, "molWeight": 92524, "crc64": "59FF5BAA10584DD7", "md5": "59EBB988508B7A5FB9A4FB2856B1818B"}}
{"primaryAccession": "Q5XM24", "text": "This is Autocrine proliferation repressor protein A protein, from Social amoeba, contains 494 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5XM24", "organism_name": "Social amoeba", "protein_name": "Autocrine proliferation repressor protein A", "length": 494, "firstPublicDate": "2008-04-08", "FUNCTION": "Inhibitor that slows proliferation of secreting cells (also known as chalone), May function by binding to cell surface receptors, Requires cfaD for activity, Overexpression slows proliferation", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the pqaA family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSKLLILLLLSLVASIFSTPLDDYVNAPDDTYKWTLNNTIEYETFTGYILELTSQTWMAEKSDWPVWKHWVSICVPKGVTTTTTFIYVDGGSNDNWKVPGSMDQTIEIVCLSSGSVSVGLTQIPNQPIIFNNDGVQRFEDDLVAYTWRQFLGNTSEPLWLARLPMTKAVVKCMDAVQEFGKTIGYNSENFVIAGASKRGWTTWLAGVVDPRIIAIVPIVMPILNMIPNMGHQFYAYGEWSFALNDYTGQGVMDYLNGPQMVELAAIVDPFSYRDRYTMPIYAIASSDDEFFLPDSPQFFWNNLTATPEKHLRIVPNAEHSLMGHQIDIILSIVTFVRLLITNQPRPTFTWDITYSEDLNSGTIVLTVPEGGIIPYKVKVWTAVTESTTRRDFRIITCMDITKCIQFIIWDPSDITPTSTGVYSITLSKPDAGWRAFFLEAEYLYAKNSIDDEYTLKFTSEVAIVPNTLPFGSCSEYNACGDGSQGDSASSTATL", "length": 494, "molWeight": 55402, "crc64": "CEBB6B6520FFA6F8", "md5": "3F728AF5A4507C12D852D5E8B8E966FB"}}
{"primaryAccession": "Q5YGP7", "text": "This is AP2-like ethylene-responsive transcription factor PLT2 protein, from Mouse-ear cress, contains 568 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5YGP7", "organism_name": "Mouse-ear cress", "protein_name": "AP2-like ethylene-responsive transcription factor PLT2", "length": 568, "firstPublicDate": "2007-08-21", "FUNCTION": "Probably acts as a transcriptional activator, Binds to the GCC-box pathogenesis-related promoter element, May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity), Master regulator of basal/root fate, Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis, Modulates the root polar auxin transport by regulating the distribution of PIN genes, Essential role in respecifying pattern and polarity in damaged roots, Direct target of the transcriptional corepressor TPL, Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the AP2/ERF transcription factor family, AP2 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNSNNWLAFPLSPTHSSLPPHIHSSQNSHFNLGLVNDNIDNPFQNQGWNMINPHGGGGEGGEVPKVADFLGVSKSGDHHTDHNLVPYNDIHQTNASDYYFQTNSLLPTVVTCASNAPNNYELQESAHNLQSLTLSMGSTGAAAAEVATVKASPAETSADNSSSTTNTSGGAIVEATPRRTLETFGQRTSIYRGVTRHRWTGRYEAHLWDNSCRREGQSRKGRQVYLGGYDKEEKAARAYDLAALKYWGPSTTTNFPITNYEKEVEEMKNMTRQEFVASIRRKSSGFSRGASMYRGVTRHHQHGRWQARIGRVAGNKDLYLGTFSTEEEAAEAYDIAAIKFRGLNAVTNFEINRYDVKAILESNTLPIGGGAAKRLKEAQALESSRKREEMIALGSNFHQYGAASGSSSVASSSRLQLQPYPLSIQQPFEHLHHHQPLLTLQNNNDISQYHDSFSYIQTQLHLHQQQTNNYLQSSSHTSQLYNAYLQSNPGLLHGFVSDNNNTSGFLGNNGIGIGSSSTVGSSAEEEFPAVKVDYDMPPSGGATGYGGWNSGESAQGSNPGGVFTMWNE", "length": 568, "molWeight": 62233, "crc64": "7C93903C46BE9029", "md5": "2E6074648BD16ACB0206C4A066DCE583"}}
{"primaryAccession": "Q5ZLF4", "text": "This is Proton-coupled zinc antiporter SLC30A5 protein, from Chicken, contains 770 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5ZLF4", "organism_name": "Chicken", "protein_name": "Proton-coupled zinc antiporter SLC30A5", "length": 770, "firstPublicDate": "2008-01-15", "FUNCTION": "Together with SLC30A6 forms a functional proton-coupled zinc ion antiporter mediating zinc entry into the lumen of organelles along the secretory pathway (PubMed:15525635), By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis (PubMed:15525635)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the cation diffusion facilitator (CDF) transporter (TC 2,A,4) family, SLC30A subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEEKYSSQALAGGGVLGPVDVPSARLTRYIVLLCFAKFLKAVGLFESYDLLKAVHLVQFIFIVKLGSAFFMVLFQKPFSSGKVVTKHQWIKIFKHAVVGCIISLLWFFGLTLCGPLRTLLLFEHSDVVVLSLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKIAEHPEGHHDSALTHVLYTVIAFLGVADHKGGVLLLVLALCCKVGFHMASRKLSVDVGGAKRLQALSHLVSVLLLCPWVIVLSLTTESKVESWSSLIMPFITVIFFVVILDFYVESICSVKMESSKCARYGSFLIFISALLFGNFWTHPITDQLRAMNKPAHHESTEHVLSGGVVVSAVFFILSANILSSPSRKGQKGTLIGYSPEGTPLYNFMGDAIQQSSQSLPRFIKESLKQILEEYDSRQIFYFLCLNLAFTFVELFYGVWTNSLGLISDGFHMLFDCSALVMGLFAALMTRWKATRIFSYGYGRVEILSGFINGLFLMVIAFFVFMESVARLVDPPDIDTNMLTPVSVGGLIVNLVGICAFSHAHSHGASRGGCHSHEHSHSYHGHSHSHGHGHSHNDHGHSHGHSHVSSGGGMNTNMRGVFLHVLADTLGSVGVIVSTTFIQQFGWLIADPLCSLFIATLIFLSVIPLLKDACQVLLLRIPPEQEKDLHAALEKIQKIDGVISYRDPHFWCHSASVVAGTIHVQVVSDVMEQRIVQQVTAILKDAGVNNLTVQVEKEAYFQHMSGLSTGFQDVLAMTQHLESMKYYKDGTYIM", "length": 770, "molWeight": 84777, "crc64": "34B4A35CEE781EF3", "md5": "F0720994EB43516C9B3E3E25F29278F1"}}
{"primaryAccession": "Q60848", "text": "This is Lymphocyte-specific helicase protein, from Mouse, contains 821 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q60848", "organism_name": "Mouse", "protein_name": "Lymphocyte-specific helicase", "length": 821, "firstPublicDate": "2006-11-28", "FUNCTION": "Plays an essential role in normal development and survival, Involved in regulation of the expansion or survival of lymphoid cells, Required for de novo or maintenance DNA methylation, May control silencing of the imprinted CDKN1C gene through DNA methylation, May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SNF2/RAD54 helicase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAEQTEPAVITPAMLEEEEQLEAAGLEKERKMLEEAQKSWDRESTEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLEKKKRSLKLTEGKSLVDGNGEKPVMKKKRGREDESYNISEVMSKEEILSVAKKHKDNEDESSSTTSLCVEDIQKNKDSNSMIKDRLSQTVRQNSKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPEIPTLLYHGTREDRRKLVKNIHKRQGTLQIHPVVVTSFEIAMRDQNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLCNKQEIFYTAIVNRTIANMFGSCEKETVELSPTGRPKRRSRKSINYSELDQFPSELEKLISQIQPEVNRERTVVEGNIPIESEVNLKLRNIMMLLRKCCNHPYMIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLVFSQMTSMLDILMDYCHLRNFIFSRLDGSMSYSEREKNIYSFNTDPDVFLFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLSQSKNFLDAKELMELLKSRDYEREVKGSREKVISDEDLELLLDRSDLIDQMKASRPIKGKTGIFKILENSEDSSAECLF", "length": 821, "molWeight": 95126, "crc64": "8DEC2F2EEFBBD2F5", "md5": "FE0872CFF2C56A850482D2A5B8155351"}}
{"primaryAccession": "Q60954", "text": "This is Homeobox protein Meis1 protein, from Mouse, contains 390 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q60954", "organism_name": "Mouse", "protein_name": "Homeobox protein Meis1", "length": 390, "firstPublicDate": "1997-11-01", "FUNCTION": "Acts as a transcriptional regulator of PAX6, Also acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2, Required for hematopoiesis, megakaryocyte lineage development and vascular patterning, May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TALE/MEIS homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDVTRSANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM", "length": 390, "molWeight": 43002, "crc64": "E0C32B5CE25E1E2C", "md5": "9F1EAF474DAB71B247C8DC82DA3D5086"}}
{"primaryAccession": "Q61048", "text": "This is WW domain-binding protein 4 protein, from Mouse, contains 376 amino acids, has 1 Matrin-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [11, 42], "description": "Matrin-type", "keyword_description": "Zinc finger", "textural_description": "Matrin-type Zinc finger"}], "meta_data": {"primaryAccession": "Q61048", "organism_name": "Mouse", "protein_name": "WW domain-binding protein 4", "length": 376, "firstPublicDate": "2005-06-07", "FUNCTION": "Involved in pre-mRNA splicing as a component of the spliceosome, May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"Matrin-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVARRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLPLPSDISEPTVSPVISTVQPTPTSNQQKEKKKKKKKKEASKGGWVEGVTADGHCYYYDLITGASQWEKPEGFQGNLKKTAAKAVWVEGLSEDGYTYYYNTETGESKWEKPEDFIPHGGDVLSSKDSGKLPDTLEDAKSSDSHSDSEGEQKKAGEASTETKKLIIKFKEKNKSTEKRIGPEIQKEKSTPKQNPSNTNEEKPKTLKKSTNPYGEWQEIKQEAESQEEVDLELPSTEGECLSTSEAGVGEIKVVFKEKTVSSLGVAADGVAPVFKKRRLENGKSRNLRQRGDDE", "length": 376, "molWeight": 42137, "crc64": "ECA7288FC94F3F83", "md5": "B6729D604F24AD12305DE6300F90BE2F"}}
{"primaryAccession": "Q61074", "text": "This is Protein phosphatase 1G protein, from Mouse, contains 542 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q61074", "organism_name": "Mouse", "protein_name": "Protein phosphatase 1G", "length": 542, "firstPublicDate": "1998-07-15", "FUNCTION": "May be involved in regulation of cell cycle", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the PP2C family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDNETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALQDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDDKDKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCQKVPPHTKSGIGTGDEPGPQGLNGEAGPEDPSRETPSQENGPTAKGHTGFSSNSEHGTEAGQISEPGTATGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEVEEEEDDSEECSEDEDGYSSEEAENEEDEDDTEEAEEDDDEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPQEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTVELQAESGKRKLEEALSTEGAEDTGNSDKKKAKRD", "length": 542, "molWeight": 58728, "crc64": "1DC72E7A66E71453", "md5": "A15E818A81CB74B1997F365C294656D7"}}
{"primaryAccession": "Q61112", "text": "This is 45 kDa calcium-binding protein protein, from Mouse, contains 361 amino acids, is soluble, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q61112", "organism_name": "Mouse", "protein_name": "45 kDa calcium-binding protein", "length": 361, "firstPublicDate": "1997-11-01", "FUNCTION": "May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the CREC family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVWLVAMTPRQSSLCGLAAHGLWFLGLVLLMDATARPANHSSTRERAANREENEIMPPDHLNGVKLEMDGHLNKDFHQEVFLGKDMDGFDEDSEPRRSRRKLMVIFSKVDVNTDRRISAKEMQHWIMEKTAEHFQEAVKENKLHFRAVDPDGDGHVSWDEYKVKFLASKGHNEREIAEAIKNHEELKVDEETQEVLGNLRDRWYQADNPPADLLLTEDEFLSFLHPEHSRGMLKFMVKEIFRDLDQDGDKQLSLPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTMEELENYMDPMNEYNALNEAKQMIAIADENQNHHLEPEEILKYSEFFTGSKLMDYARNVHEEF", "length": 361, "molWeight": 42064, "crc64": "2599E99F5F81A913", "md5": "FDA542FB7228DFD3FEED662C7421AE7D"}}
{"primaryAccession": "Q61477", "text": "This is Neuroblastoma suppressor of tumorigenicity 1 protein, from Mouse, contains 178 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q61477", "organism_name": "Mouse", "protein_name": "Neuroblastoma suppressor of tumorigenicity 1", "length": 178, "firstPublicDate": "1997-11-01", "FUNCTION": "Possible candidate as a tumor suppressor gene of neuroblastoma, May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the DAN family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLWVLVGAVLPVMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKIVHCSCQACGKEPSHEGLNVYVQGEDSPGSQPGPHSHAHPHPGGQTPEPEEPPGAPQVEEEGAED", "length": 178, "molWeight": 19107, "crc64": "C51D74C82ED904DD", "md5": "7944ACB2549AA64280DDCA07C091FB10"}}
{"primaryAccession": "Q61606", "text": "This is Glucagon receptor protein, from Mouse, contains 485 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q61606", "organism_name": "Mouse", "protein_name": "Glucagon receptor", "length": 485, "firstPublicDate": "1997-11-01", "FUNCTION": "G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis, Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis, Plays an important role in mediating the responses to fasting, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase, Promotes activation of adenylate cyclase, Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPLTQLHCPHLLLLLLVLSCLPEAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQPWRNASQCQLDDEEIEVQKGVAKMYSSQQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAMAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSLATFSERSFFSLYLGIGWGAPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVFLALLINFFIFVHIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSTKLFFDLFLSSFQGLLVAVLYCFLNKEVQAELMRRWRQWQEGKALQEERLASSHGSHMAPAGPCHGDPCEKLQLMSAGSSSGTGCVPSMETSLASSLPRLADSPT", "length": 485, "molWeight": 54929, "crc64": "578EB30BF281E67A", "md5": "405DD5E5B8B0A9AD92A682B28C7838BD"}}
{"primaryAccession": "Q62233", "text": "This is Homeobox protein SIX3 protein, from Mouse, contains 333 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q62233", "organism_name": "Mouse", "protein_name": "Homeobox protein SIX3", "length": 333, "firstPublicDate": "1997-11-01", "FUNCTION": "Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes, During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon (PubMed:18094027), Acts as a direct upstream activator of SHH expression in the rostral diencephalon ventral midline and that in turn SHH maintains its expression (PubMed:18775421), In addition, Six3 activity is required for the formation of the telencephalon, During postnatal stages of brain development is necessary for ependymal cell maturation by promoting the maturation of radial glia into ependymal cells through regulation of neuroblast proliferation and migration (PubMed:22071110), Acts on the proliferation and differentiation of neural progenitor cells through activating transcription of CCND1 AND CCND2 (PubMed:17576749), During early lens formation plays a role in lens induction and specification by activating directly PAX6 in the presumptive lens ectoderm (PubMed:17066077), In turn PAX6 activates SIX3 resulting in activation of PDGFRA and CCND1 promoting cell proliferation (PubMed:12072567), Also is required for the neuroretina development by directly suppressing WNT8B expression in the anterior neural plate territory (PubMed:20890044), Its action during retina development and lens morphogenesis is TLE5 and TLE4-dependent manner, Furthermore, during eye development regulates several genes expression, Before and during early lens development represses the CRYGF promoter by binding a SIX repressor element (PubMed:11139622), Directly activates RHO transcription, or cooperates with CRX or NRL (PubMed:17666527), Six3 functions also in the formation of the proximodistal axis of the optic cup (PubMed:12163408), and promotes the formation of optic vesicles-like structures (PubMed:11458394), During pituitary development, acts in parallel or alternatively with HESX1 to control cell proliferation through Wnt/beta-catenin pathway (PubMed:18694563), Plays a role in eye development by suppressing WNT1 expression and in dorsal-ventral patterning by repressing BMP signaling pathway (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SIX/Sine oculis homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVFRSPLDLYSSHFLLPNFADSHHCSLLLASSGGGSGASGGGGGAGGGGGGNRAGGGGAGGAGGGSGGGGSRAPPEELSMFQLPTLNFSPEQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGNFRDLYHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIGPSGMRSLAEPGCPTHGSAESPSTAASPTTSVSSLTERADTGTSILSVTSSDSECDV", "length": 333, "molWeight": 35593, "crc64": "1AD7D3C4388043B9", "md5": "24415084B49C4BF344146FE3CE7080AD"}}
{"primaryAccession": "Q62414", "text": "This is Neurogenic differentiation factor 2 protein, from Mouse, contains 383 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q62414", "organism_name": "Mouse", "protein_name": "Neurogenic differentiation factor 2", "length": 383, "firstPublicDate": "1997-11-01", "FUNCTION": "Transcriptional regulator implicated in neuronal determination, Mediates calcium-dependent transcription activation by binding to E box-containing promoter, Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons, Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression, Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex, Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis, Associates with chromatin to the DPYSL3 E box-containing promoter", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLTRLFSEPGLLSDVPKFASWGDGDDDEPRSDKGDAPPQPPPAPGSGAPGPARAAKPVSLRGGEEIPEPTLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPYPYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDYNSSEYEGPLSPPLCLNGNFSLKQDSSPDHEKSYHYSMHYSALPGSRPTGHGLVFGSSAVRGGVHSENLLSYDMHLHHDRGPMYEELNAFFHN", "length": 383, "molWeight": 41493, "crc64": "68342005219829B1", "md5": "25CC940943D86669817AA81E1259107C"}}
{"primaryAccession": "Q63089", "text": "This is Solute carrier family 22 member 1 protein, from Rat, contains 556 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q63089", "organism_name": "Rat", "protein_name": "Solute carrier family 22 member 1", "length": 556, "firstPublicDate": "2008-05-20", "FUNCTION": "Functional isoform capable of transporting TEA", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPTVDDVLEQVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPGHYCQNPGVAELSQRCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLVANRSQLPLGPCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSVSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQMAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTRAVRIMEQIAQKNGKVPPADLKMLCLEEDASEKRSPSFADLFRTPNLRKHTVILMYLWFSCAVLYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVTGAACLLMIFIPHELHWLNVTLACLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLMEVWQALPLILFGVLGLTAGAMTLLLPETKGVALPETIEEAENLGRRKSKAKENTIYLQVQTGKSSST", "length": 556, "molWeight": 61541, "crc64": "9F42131CCCEC0920", "md5": "ED208209AAA25A1CFDA0F9FFA66E0BA1"}}
{"primaryAccession": "Q63262", "text": "This is POU domain, class 3, transcription factor 3 protein, from Rat, contains 497 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q63262", "organism_name": "Rat", "protein_name": "POU domain, class 3, transcription factor 3", "length": 497, "firstPublicDate": "1998-07-15", "FUNCTION": "Transcription factor that acts synergistically with SOX11 and SOX4, Plays a role in neuronal development, Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the POU transcription factor family, Class-3 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATAASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPRPPPPPPQGPDVKGGVGREDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGAGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSADTPPPHHGLQTSVQ", "length": 497, "molWeight": 50226, "crc64": "00640505E343ABC2", "md5": "901BEC083C74B1FBF216A87105DE91EC"}}
{"primaryAccession": "Q63520", "text": "This is Synaptonemal complex protein 3 protein, from Rat, contains 257 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q63520", "organism_name": "Rat", "protein_name": "Synaptonemal complex protein 3", "length": 257, "firstPublicDate": "1998-07-15", "FUNCTION": "Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:8289794, PubMed:9933407), Required for centromere pairing during meiosis in male germ cells, Required for normal meiosis during spermatogenesis and male fertility, Plays a lesser role in female fertility, Required for efficient phosphorylation of HORMAD1 and HORMAD2", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the XLR/SYCP3 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRGCGEVGAVDCSPEQLNKHLKMVPGGRKHSGKSGKPPLIDQPKKAFDFEKEDKDLSGSEEDAVDEKTQVFDKHGKKRSAGIIEDVGGEVQNMLEKFGADINKALLAKKKRIEMYTKASFKASNQKIEQIWKTQQEEIQKLNNEYSQQFLSVLQQWELDMQKFEEQGEKLTNLFRQQQKIFQQTRIVQSQRMKAIKQLHEQFIKSLEDVEKNNDNLFTGTQSELKKEMAMLQKKVMMETQQQEMANVRKSLQSMLF", "length": 257, "molWeight": 29733, "crc64": "97C709F56918AF32", "md5": "801A17D9F2D5DB3965FC712A87BD7B80"}}
{"primaryAccession": "Q63707", "text": "This is Dihydroorotate dehydrogenase (quinone), mitochondrial protein, from Rat, contains 395 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q63707", "organism_name": "Rat", "protein_name": "Dihydroorotate dehydrogenase (quinone), mitochondrial", "length": 395, "firstPublicDate": "1997-11-01", "FUNCTION": "Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor, Required for UMP biosynthesis via de novo pathway", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the dihydroorotate dehydrogenase family, Type 2 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAWRQLRKRALDAVIILGGGGLLFTSYLTATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR", "length": 395, "molWeight": 42663, "crc64": "4C7E1A9C5E5E60EB", "md5": "436079B91A10A03A0F8C418E33929BF7"}}
{"primaryAccession": "Q640Q5", "text": "This is PAN2-PAN3 deadenylation complex subunit Pan3 protein, from Mouse, contains 837 amino acids, has 1 C3H1-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [49, 77], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "Q640Q5", "organism_name": "Mouse", "protein_name": "PAN2-PAN3 deadenylation complex subunit Pan3", "length": 837, "firstPublicDate": "2007-03-20", "FUNCTION": "Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover, PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP), PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex, Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenylation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1, PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, PAN3 family", "domain_description": {"C3H1-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNSGGGGGLPPPSAAASPSSSSLAAAVAVAVAASSGVGGVPGGPAAAAGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLALAAAAGAAFPPGALPGGGAGPPAGPKKPELGVPGAATAGGGLDGPRVAIPGMDGGALTDASLTESYFSTSFIGVNGFGSPVETKYPLMQRMTSSSSSPSLLNDSAKPYTGHDLLTSSASSLFNDFGALNISQRRKTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPGMSLSAGSSPLHSPKITPHTSPAPRRRSHTPNPASFMVPPSASTPANNPAPQPPSSGQVIQKETVGGTTYFYTDTTPAPLTGMVFPNYHIYPPTAPHVAYMQPKANAPSFFMADELRQELINRHLITMAQIDQADMPAVPTEVDSYHSLFPLEPLPPPNRIQKSSNFGYITSCYKAVNSKDDLPYCLRRIHGFRLVNTKCMVLVDMWKKIQHSNIVTLREVFTTKAFAEPSLVFAYDFHAGGETMMSRHFNDPNSDAYFTKRKWGQHDGPLPRQHAGLLPESLIWAYIVQLSSALRTIHTAGLACRVMDPTKILITSKTRLRVNCVGVFDVLTFDNSQNNNPLALMAQYQQADLISLGKVVLALACNSLAGIQRENLQKAMELVTINYSSDLKNLILYLLTDQNRMRSVNDIMPMIGARFYTQLDAAQMRNDVIEEDLAKEVQNGRLFRLLAKLGTINERPEFQKDPTWSETGDRYLLKLFRDHLFHQVTEAGAPWIDLSHIISCLNKLDAGVPEKISLISRDEKSVLVVTYSDLKRCFENTFQELIAAANGNDRNSN", "length": 837, "molWeight": 89745, "crc64": "323CACB0F32E745A", "md5": "CABED4291BACB026E65459417D97B0F1"}}
{"primaryAccession": "Q642G2", "text": "This is Sclerostin domain-containing protein 1 protein, from Rat, contains 206 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q642G2", "organism_name": "Rat", "protein_name": "Sclerostin domain-containing protein 1", "length": 206, "firstPublicDate": "2005-03-29", "FUNCTION": "Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner (By similarity), May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction, Enhances Wnt signaling and inhibits TGF-beta signaling", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the sclerostin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLPPAIHLSLIPLLCILMKNCLAFKNDATEILYSHVVKPVSAHPSSNSTLNQARNGGRHFSSTGLDRNSRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESVSPAKPAQHHRERKRASKSSKHSLS", "length": 206, "molWeight": 23136, "crc64": "52BD602431C6DD15", "md5": "FF942821634BA22B8597D10D851AED9A"}}
{"primaryAccession": "Q64368", "text": "This is Deleted in azoospermia-like protein, from Mouse, contains 298 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q64368", "organism_name": "Mouse", "protein_name": "Deleted in azoospermia-like", "length": 298, "firstPublicDate": "2003-01-17", "FUNCTION": "RNA-binding protein, which is essential for gametogenesis in both males and females, Plays a central role during spermatogenesis, Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the RRM DAZ family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSATTSEAPNSAVSREASTQSSSATTSQGYVLPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFYNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCTYHVQPRPLIFNPPPPPQFQSVWSSPNAETYMQPPTMMNPITQYVQAYPPYPSSPVQVITGYQLPVYNYQMPPQWPAGEQRSYVIPPAYTTVNYHCSEVDPGADILPNECSVHDAAPASGNGPQKKSVDRSIQTVVSCLFNPENRLRNSLVTQDDYFKDKRVHHFRRSRAVLKSDHLC", "length": 298, "molWeight": 33313, "crc64": "FBF457BC388DB974", "md5": "88595AE7D2432FBEAE33C9183D30C4AC"}}
{"primaryAccession": "Q66K79", "text": "This is Carboxypeptidase Z protein, from Human, contains 652 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q66K79", "organism_name": "Human", "protein_name": "Carboxypeptidase Z", "length": 652, "firstPublicDate": "2006-10-17", "FUNCTION": "Cleaves substrates with C-terminal arginine residues, Probably modulates the Wnt signaling pathway, by cleaving some undefined protein, May play a role in cleavage during prohormone processing", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPPPLPLLLLTVLVVAAARPGCEFERNPAGECHRPPAADSATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPPTFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYILWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGPHDPLGGASSLGEATEPDPLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY", "length": 652, "molWeight": 73655, "crc64": "BFA1EA7753E63F98", "md5": "0A0E8DAC1911C93803DAFCCCBCD30D20"}}
{"primaryAccession": "Q67Y93", "text": "This is Cyclin-dependent kinase inhibitor 1 protein, from Mouse-ear cress, contains 191 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q67Y93", "organism_name": "Mouse-ear cress", "protein_name": "Cyclin-dependent kinase inhibitor 1", "length": 191, "firstPublicDate": "2007-07-10", "FUNCTION": "Binds and inhibits CYCD2-1/CDKA-1 kinase complex activity, Regulates cell division which is crucial for plant growth, development and morphogenesis, Functions in turning cells from a mitotic to an endoreplicating cell cycle mode, Acts cell- and non-cell-autonomously to regulate endoreduplication by allowing S phase progression, but blocking entry into mitosis, Keeps on the one hand the plant cell cycle locally controlled, and on the other hand provides a possibility of linking cell cycle control in single cells with the supracellular organization of a tissue or an organ, May target specifically CDKA-1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CDI family, ICK/KRP subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVRKYRKAKGIVEAGVSSTYMQLRSRRIVYVRSEKSSSVSVVGDNGVSSSCSGSNEYKKKELIHLEEEDKDGDTETSTYRRGTKRKLFENLREEEKEELSKSMENYSSEFESAVKESLDCCCSGRKTMEETVTAEEEEKAKLMTEMPTESEIEDFFVEAEKQLKEKFKKKYNFDFEKEKPLEGRYEWVKLE", "length": 191, "molWeight": 22283, "crc64": "0477A91E277C46B2", "md5": "6B9436255E6295ADCAFFF4E09D7CAC03"}}
{"primaryAccession": "Q680Q4", "text": "This is E3 SUMO-protein ligase SIZ1 protein, from Mouse-ear cress, contains 884 amino acids, has 1 PHD-type Zinc finger, has 1 SP-RING-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [112, 168], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}, {"location": [346, 429], "description": "SP-RING-type", "keyword_description": "Zinc finger", "textural_description": "SP-RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q680Q4", "organism_name": "Mouse-ear cress", "protein_name": "E3 SUMO-protein ligase SIZ1", "length": 884, "firstPublicDate": "2005-08-30", "FUNCTION": "E3 SUMO protein ligase involved in regulation processes, Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses (PubMed:15894620), Functions as an upstream negative regulator of salicylic acid (SA) accumulation and subsequent SA-mediated systemic acquired resistance (SAR) signaling, Probably not involved in jasmonic acid (JA)-mediated defense response, Participates in abiotic stress-induced sumoylation, Controls heat shock-induced SUMO1 and SUMO2 conjugation and facilitates basal thermotolerance, Involved in freezing tolerance by mediating sumoylation of ICE1, a transcription activator of the cold signaling regulator CBF3/DREB1A, Acts as positive regulator of drought stress tolerance, Acts as floral repressor that promotes FLC expression by repressing FLD activity through sumoylation, Acts as negative regulator of abscisic acid (ABA) signaling through ABI5 sumoylation, Mediates sumoylation of SCE1, GTE3 and GTE5, Functions as negative regulator of SnRK1 signaling through sumoylation of several components of the SnRK1 complex (PubMed:26662259)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the PIAS family", "domain_description": {"PHD-type Zinc finger": 1, "SP-RING-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDLEANCKEKLSYFRIKELKDVLTQLGLSKQGKKQELVDRILTLLSDEQAARLLSKKNTVAKEAVAKLVDDTYRKMQVSGASDLASKGQVSSDTSNLKVKGEPEDPFQPEIKVRCVCGNSLETDSMIQCEDPRCHVWQHVGCVILPDKPMDGNPPLPESFYCEICRLTRADPFWVTVAHPLSPVRLTATTIPNDGASTMQSVERTFQITRADKDLLAKPEYDVQAWCMLLNDKVLFRMQWPQYADLQVNGVPVRAINRPGGQLLGVNGRDDGPIITSCIRDGVNRISLSGGDVRIFCFGVRLVKRRTLQQVLNLIPEEGKGETFEDALARVRRCIGGGGGDDNADSDSDIEVVADFFGVNLRCPMSGSRIKVAGRFLPCVHMGCFDLDVFVELNQRSRKWQCPICLKNYSVEHVIVDPYFNRITSKMKHCDEEVTEIEVKPDGSWRVKFKRESERRELGELSQWHAPDGSLCPSAVDIKRKMEMLPVKQEGYSDGPAPLKLGIRKNRNGIWEVSKPNTNGLSSSNRQEKVGYQEKNIIPMSSSATGSGRDGDDASVNQDAIGTFDFVANGMELDSISMNVDSGYNFPDRNQSGEGGNNEVIVLSDSDDENDLVITPGPAYSGCQTDGGLTFPLNPPGIINSYNEDPHSIAGGSSGLGLFNDDDEFDTPLWSFPSETPEAPGFQLFRSDADVSGGLVGLHHHSPLNCSPEINGGYTMAPETSMASVPVVPGSTGRSEANDGLVDNPLAFGRDDPSLQIFLPTKPDASAQSGFKNQADMSNGLRSEDWISLRLGDSASGNHGDPATTNGINSSHQMSTREGSMDTTTETASLLLGMNDSRQDKAKKQRSDNPFSFPRQKRSNNEQDHQTRHRSLNKICIILCAGKN", "length": 884, "molWeight": 97034, "crc64": "5E44EA57FE896113", "md5": "1FDC76DE9AD3D16392124DCDF7DFDB31"}}
{"primaryAccession": "Q681K7", "text": "This is Protein GAMETE EXPRESSED 1 protein, from Mouse-ear cress, contains 593 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q681K7", "organism_name": "Mouse-ear cress", "protein_name": "Protein GAMETE EXPRESSED 1", "length": 593, "firstPublicDate": "2012-04-18", "FUNCTION": "Has a dual function during gametophyte development and early embryogenesis, Required for correct pollen maturation", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDRFSRKCLLFLLLIILLDSPLTCHSWGWFSSSSSSAEDPYSSSFSRSRKSNPDFSMEVFSDQKAVQVLENKLVGLTSCWQNAYSYLLAGCKETIATEEKRKRFAWYLSDCFIKDSGRPAFPTCKDESVMMSCLKKLDDHEHKIYLDFLLETNTICQQLQSNAFKNEIERLVNELKNTAQYTEDKLDILESKSDALIQTSSMIHDSLGSLDVRVQNVASVTNTLETSVSGLSQQTVEISQEQKNIAESQLALRDGQVKMKETLKDGMDMFLDAYTNIQEGVDKLKSDTEQIEVEISVLGNNLSTKMIDLQSTTDDIGTKTRSSLDKQQKLLDGQTVALDGIQFLTRFQSEALQESRNTLQRLKEFSQEQQEDLAKRQEKLQEVHDHLFENSKSMLEAQVAFEAKQANMFVALDKLFALHNAMLLESRVIKAFVIYFLSIFVIYMFTSTKQTYIIRPRLYIGLCVTLALEVASLRYVNDTERQAWMINLIRSLFALLASAQLLHAALSYRDYEVLNHQILLRLVDKVNDMQSKKELSYDEDTESEVDWTSWVDTDLTDDDDNLADPDYKIPLLIKDNPVTTSSLTRRLYNFRPR", "length": 593, "molWeight": 67963, "crc64": "C45A1E305703223B", "md5": "1768F6E88C4B6A42F6090829D9F5CD79"}}
{"primaryAccession": "Q68CQ4", "text": "This is U3 small nucleolar RNA-associated protein 25 homolog protein, from Human, contains 756 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q68CQ4", "organism_name": "Human", "protein_name": "U3 small nucleolar RNA-associated protein 25 homolog", "length": 756, "firstPublicDate": "2006-10-31", "FUNCTION": "Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (By similarity), Essential for embryonic development in part through the regulation of p53 pathway, Controls the expansion growth of digestive organs and liver (PubMed:25007945, PubMed:27657329, PubMed:23357851), Also involved in the sympathetic neuronal development (By similarity), Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53 (PubMed:23357851, PubMed:27657329)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the UTP25 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGKRGSRSQSQLLNTLTKKQKKHLRDFGEEHPFYDRVSRKEAKPQICQLSESSDSSDSESDSESEPQQVSGYHRLLATLKNVSEEEEEDEEEEEEEDSIVDDAEMNDEDGGSDVSVEEEMAAESTESPENVALSADPEGKEDGEEPPGTSQTSPEEFTDAKHESLFSLETNFLEEESGDNSSLKASQDPFLQHVNKELKEKAIQAVATNPKTTHELKWPILGQLFFSSKFQKLETFKPPKDIDLKSLHLQKPLESTWTKTNSQFLSGPQKSSSPFTPLQKELFLIMNSYRDLFYPERTALKNGEEIRHVYCLHVINHILKANAQVLGNNSRRRSQKFGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEGDSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKYCVNMQGQVAVRNVPMTGSISHVLVQLPHVFQRMEAENLASVIDARFNFFVNKILPQYRDAVMSHTLIYIPSYFDFVRLRNYFKKEELNFTHICEYTQKSGVSRARHFFLQGEKQFLLFTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEICNMLRATNRGEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSNKNVHLFITGEK", "length": 756, "molWeight": 87055, "crc64": "A8821B0AC4BF4067", "md5": "CAA20FEA668C3D933BDD7D9727F25525"}}
{"primaryAccession": "Q68CZ6", "text": "This is HAUS augmin-like complex subunit 3 protein, from Human, contains 603 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q68CZ6", "organism_name": "Human", "protein_name": "HAUS augmin-like complex subunit 3", "length": 603, "firstPublicDate": "2007-09-11", "FUNCTION": "Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the HAUS3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSCGNEFVETLKKIGYPKADNLNGEDFDWLFEGVEDESFLKWFCGNVNEQNVLSERELEAFSILQKSGKPILEGAALDEALKTCKTSDLKTPRLDDKELEKLEDEVQTLLKLKNLKIQRRNKCQLMASVTSHKSLRLNAKEEEATKKLKQSQGILNAMITKISNELQALTDEVTQLMMFFRHSNLGQGTNPLVFLSQFSLEKYLSQEEQSTAALTLYTKKQFFQGIHEVVESSNEDNFQLLDIQTPSICDNQEILEERRLEMARLQLAYICAQHQLIHLKASNSSMKSSIKWAEESLHSLTSKAVDKENLDAKISSLTSEIMKLEKEVTQIKDRSLPAVVRENAQLLNMPVVKGDFDLQIAKQDYYTARQELVLNQLIKQKASFELLQLSYEIELRKHRDIYRQLENLVQELSQSNMMLYKQLEMLTDPSVSQQINPRNTIDTKDYSTHRLYQVLEGENKKKELFLTHGNLEEVAEKLKQNISLVQDQLAVSAQEHSFFLSKRNKDVDMLCDTLYQGGNQLLLSDQELTEQFHKVESQLNKLNHLLTDILADVKTKRKTLANNKLHQMEREFYVYFLKDEDYLKDIVENLETQSKIKAVSLED", "length": 603, "molWeight": 69650, "crc64": "C65B80CC58F326E9", "md5": "223EFCEC72B414BF134A1EC4A67C21CF"}}
{"primaryAccession": "Q69YI7", "text": "This is Nuclear apoptosis-inducing factor 1 protein, from Human, contains 327 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q69YI7", "organism_name": "Human", "protein_name": "Nuclear apoptosis-inducing factor 1", "length": 327, "firstPublicDate": "2005-07-05", "FUNCTION": "Induces apoptosis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the NAIF1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAVPAKKRKMNFSEREVEIIVEELELKKHLLVNHFNAGVPLAAKSAAWHGILRRVNAVATCRRELPEVKKKWSDLKTEVRRKVAQVRAAVEGGEAPGPTEEDGAGGPGTGGGSGGGGPAVAPVLLTPMQQRICNLLGEATIISLPSTTEIHPVALGPSATAAAATVTLTQIPTETTYHTLEEGVVEYCTAEAPPPLPPETPVDMMAQHADTSVKPQALKSRIALNSAKLIQEQRVTNLHVKEIAQHLEQQNDLLQMIRRSQEVQACAQERQAQAMEGTQAALSVLIQVLRPMIKDFRRYLQSNTANPAPASDPGQVAQNGQPDSIIQ", "length": 327, "molWeight": 35164, "crc64": "52FC0BAB88BC0EAA", "md5": "A9ADF10CE7834C22248C2D41DAC4073C"}}
{"primaryAccession": "Q6DJT9", "text": "This is Zinc finger protein PLAG1 protein, from Human, contains 500 amino acids, has 7 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [34, 56], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [62, 86], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [92, 114], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [121, 143], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [150, 172], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [185, 207], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [213, 236], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q6DJT9", "organism_name": "Human", "protein_name": "Zinc finger protein PLAG1", "length": 500, "firstPublicDate": "2007-07-10", "FUNCTION": "Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed, Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction, Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas, Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood, Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 7}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ", "length": 500, "molWeight": 55909, "crc64": "CF022A132A1BFD43", "md5": "BC9019B5E0DA9B1CD442D3348058552A"}}
{"primaryAccession": "Q6E434", "text": "This is Telomeric DNA-binding factor trf1 protein, from Fission yeast, contains 485 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6E434", "organism_name": "Fission yeast", "protein_name": "Telomeric DNA-binding factor trf1", "length": 485, "firstPublicDate": "2007-06-12", "FUNCTION": "Binds the telomeric double-stranded TTACAGG repeat and regulates telomere length", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSKRSLDPSDDFKGQKRLAIDPESTALEQDRQMLQQLSEQNSELEPQNVAPNAEIPLGFDLSGIQFNMTPDFYLRMNQGMDYAFNQPNPIATPQQLLRTSLIPTLGNLSNIILSILGKPVQEASAIVTNPASEMGMAFTKVMNMFRMVKDIYTEESFIYSSAIGMRTPSQRSTTRRANLAIFLAAVYGALQIGFFHLNENFLEVFAPDESNILTNQGTLYMELKTQAYISAMAQAERPKGDILNDLFPSDMAHRFLIRRNAKLDDKLTYVEKQIIEKCTARKERLANFSPQEALNEVYPWGKFLSEIACYIHNNYSSISAIPIPANSFKRRSKKNGLRFKAGEAESSPSESGSDLTDSLAFGIPSSTFDGSSETQNVSSVVLYDQVRHMTNNNLNNKRTRRVANRRSWTKEEEEALLDGLDLVKGPRWSQILELYGPGGKKSEVLKYRNQVQLKDKARNMKLFFLKSGQVVPAALQCVTGDLRRD", "length": 485, "molWeight": 54604, "crc64": "DF3DA46B4BB2C4A5", "md5": "4EAD1CF27CD2FF67CC46C92574A8E970"}}
{"primaryAccession": "Q6IWZ0", "text": "This is L-amino-acid oxidase protein, from California sea hare, contains 535 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6IWZ0", "organism_name": "California sea hare", "protein_name": "L-amino-acid oxidase", "length": 535, "firstPublicDate": "2011-10-19", "FUNCTION": "Catalyzes the oxidative deamination of positively charged L-amino acids L-Lys and L-Arg and, much less efficiently, of amino acids L-His and L-Tyr, Has antimicrobial activity, Inhibits growth of Gram-negative bacteria E,coli strain MC4100 (MIC=0,62 ug/ml), E,coli strain C921-b2, S,typhimurium strain AA 140 (MIC=0,62 ug/ml), P,aeruginosa strain PAO1 (MIC=0,31 ug/ml) and V,harveyi strain BB170 (MIC=0,25 ug/ml), Inhibits growth of Gram-positive bacteria S,aureus strain 6835 (MIC=0,31 ug/ml), S,pyogenes strain NZ131 (MIC=0,62 ug/ml), B,subtilis strain 168 (MIC=2,50 ug/ml) and B,subtilis strain WB600 (MIC=2,50 ug/ml), The antibacterial effect can be bacteriostatic, mediated mostly by H(2)O(2), as well as bactericidal, The latter appears to be due to unstable intermediates generated from alpha-keto-epsilon-aminocaproic acid, an intermediate of escapin-deaminated L-Lys, and H(2)O(2), The bactericidal effect is stronger at lower pH levels, Intermediates generated from L-Arg have no bactericidal effect, Inhibits growth of yeast species S,cerevisiae strain BY4761 (MIC=5,0 ug/ml) and C,krusei (MIC=5,0 ug/ml), Inhibits growth of C,sphaerospermum in a lysine-dependent manner, As components of ink, products from escapin's enzymatic activity may play a role in deterring eukaryotic predators", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the flavin monoamine oxidase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSAFLLLACALVISVHADGVCRNRRQCNKEVCGSSYDVAIVGAGPGGANSAYMLRESGLDIAVFEYSDRVGGRLFTYQLPNTPDVNLEIGGMRFIEGAMHRLWKVISELGLTPKVFKEGFGKEGRQRFYLRGQSLTKKQVKSGDVPYDLSPEEKANQGRLVEYYLEKLTGLQLNGGPLKREVALKLTVPDGRFLYDLTFDEALDLVASPEGKEFARDTHVFTSEVTLDASAISIFDDHLGEDYYGSEIYTLEEGMSSVPQGLLQTFLDAAKSNEFFPNNHLKALRRRTNGQYVLYFEPTTSKDGQTTINYLEPLKVVCAQRVILAMPVYALRQLDWSQLRNDRATQAYRAVRPMPASKVFMTFDQPWWLQNERKSWVTKSDALFSQMYDWQKSEASGDYILIASYADGLKAQYLRELKNQGEDIPGSDPGYNQVTVPLKDAILEHLTEAYGVERDSIPEPVTAASQFWTDYPFGCGWITWRAGYHFDDVISTMRRPSLKDEVYVVGSDYSWGLISSWIEGALETSENVINDYFL", "length": 535, "molWeight": 60300, "crc64": "4F288F95F9B423FC", "md5": "BA4E0071BA444BA248571F676793F6C5"}}
{"primaryAccession": "Q6J9Q2", "text": "This is Ethylene-responsive transcription factor ERF086 protein, from Mouse-ear cress, contains 348 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6J9Q2", "organism_name": "Mouse-ear cress", "protein_name": "Ethylene-responsive transcription factor ERF086", "length": 348, "firstPublicDate": "2007-06-12", "FUNCTION": "Probably acts as a transcriptional activator, May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity), Involved in the control of cell division patterns during the early lateral root primordium development, Acts downstream of auxin signaling (PubMed:17630277), Regulated by ARF7 and ARF19 in response to auxin, Co-acts with LBD16 and LBD18 to control lateral root development (PubMed:23749813), Involved in the determination of floral meristem identity and suppression of bract growth, Required for proper conversion of secondary inflorescences to flowers, Acts together with NPR5/BOP2 and NPR6/BOP1 to promote expression of LFY and AP1, two central regulators of floral meristem identity (PubMed:19482972)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the AP2/ERF transcription factor family, ERF subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSTSKTLDHNKPFETSQTQMGFALIHQNTSANTTTTTTTGERRGRRSKQAEPGRFLGVRRRPWGRYAAEIRDPTTKERHWLGTFDTAHEAALAYDRAALSMRGTQARTNFVYTPTDVHTILTNPNLHSLIVSPYNNNQSFLPNSSPQFVIDHHPHYQNYHQPQQPKHTLPQTVLPAASFKTPVRHQSVDIQAFGNSPQNSSSNGSLSSSLDEENNFFFSLTSEEHNKSNNNSGYLDCIVPNHCLKPPPEATTTQNQAGASFTTPVASKASEPYGGFSNSYFEDGEMMMMNHHEFGSCDLSAMITNYGAAAASMSMEDYGMMEPQDLSSSSIAAFGDVVADTTGFYSVF", "length": 348, "molWeight": 38455, "crc64": "D9017FC0932CE4BC", "md5": "FB220BF741034A2682BB98F70E9F2F7B"}}
{"primaryAccession": "Q6KCM7", "text": "This is Mitochondrial adenyl nucleotide antiporter SLC25A25 protein, from Human, contains 469 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6KCM7", "organism_name": "Human", "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A25", "length": 469, "firstPublicDate": "2008-02-05", "FUNCTION": "Electroneutral antiporter that most probably mediates the transport of adenyl nucleotides through the inner mitochondrial membrane, Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it could have a broader specificity for adenyl nucleotides, By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR", "length": 469, "molWeight": 52663, "crc64": "A50825AA95DBD4BE", "md5": "6BFC17A2E793ADB4358C95CB05489187"}}
{"primaryAccession": "Q6L9W6", "text": "This is Beta-1,4-N-acetylgalactosaminyltransferase 3 protein, from Human, contains 998 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6L9W6", "organism_name": "Human", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase 3", "length": 998, "firstPublicDate": "2006-10-17", "FUNCTION": "Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans, Mediates the N,N'-diacetyllactosediamine formation on gastric mucosa", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the chondroitin N-acetylgalactosaminyltransferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGSPRAARPPLLLRPVKLLRRRFRLLLALAVVSVGLWTLYLELVASAQVGGNPLNRRYGSWRELAKALASRNIPAVDPHLQFYHPQRLSLEDHDIDQGVSSNSSYLKWNKPVPWLSEFRGRANLHVFEDWCGSSIQQLRRNLHFPLYPHIRTTLRKLAVSPKWTNYGLRIFGYLHPFTDGKIQFAIAADDNAEFWLSLDDQVSGLQLLASVGKTGKEWTAPGEFGKFRSQISKPVSLSASHRYYFEVLHKQNEEGTDHVEVAWRRNDPGAKFTIIDSLSLSLFTNETFLQMDEVGHIPQTAASHVDSSNALPRDEQPPADMLRPDPRDTLYRVPLIPKSHLRHVLPDCPYKPSYLVDGLPLQRYQGLRFVHLSFVYPNDYTRLSHMETHNKCFYQENAYYQDRFSFQEYIKIDQPEKQGLEQPGFEENLLEESQYGEVAEETPASNNQNARMLEGRQTPASTLEQDATDYRLRSLRKLLAQPREGLLAPFSKRNSTASFPGRTSHIPVQQPEKRKQKPSPEPSQDSPHSDKWPPGHPVKNLPQMRGPRPRPAGDSPRKTQWLNQVESYIAEQRRGDRMRPQAPGRGWHGEEEVVAAAGQEGQVEGEEEGEEEEEEEDMSEVFEYVPVFDPVVNWDQTFSARNLDFQALRTDWIDLSCNTSGNLLLPEQEALEVTRVFLKKLNQRSRGRYQLQRIVNVEKRQDQLRGGRYLLELELLEQGQRVVRLSEYVSARGWQGIDPAGGEEVEARNLQGLVWDPHNRRRQVLNTRAQEPKLCWPQGFSWSHRAVVHFVVPVKNQARWVQQFIKDMENLFQVTGDPHFNIVITDYSSEDMDVEMALKRSKLRSYQYVKLSGNFERSAGLQAGIDLVKDPHSIIFLCDLHIHFPAGVIDAIRKHCVEGKMAFAPMVMRLHCGATPQWPEGYWEVNGFGLLGIYKSDLDRIGGMNTKEFRDRWGGEDWELLDRILQAGLDVERLSLRNFFHHFHSKRGMWSRRQMKTL", "length": 998, "molWeight": 114975, "crc64": "1FDA8490C8FA1D0B", "md5": "CE7725ED2C5E0F323C2F3B605BFD69C8"}}
{"primaryAccession": "Q6NLW5", "text": "This is Protein XRI1 protein, from Mouse-ear cress, contains 300 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6NLW5", "organism_name": "Mouse-ear cress", "protein_name": "Protein XRI1", "length": 300, "firstPublicDate": "2009-06-16", "FUNCTION": "Required for mitotic division of the generative cell nucleus and the development of mature tricellular pollen grains, and for male and female meiosis", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDYGDDDRSSSWNWQVDNYNHQPQSHFSDVPDCTMTEVTLNQEDHSYMFDDENTPVKACSELGYHVTTEDTNRKMEVHSETRSALKRRRMLQFEDQPETSLFSSESFSAILKSSARDDTFDELLPEGSQLIEGFSEDASASSFEGLDLYAEEWYADCLNDAETPMLPDDLNFGSPDVQVDISEYLNVPPETETREVQRPVTRSSPNVIFKGRKSFSRPVSKLPSSIIYPFAFIKPCGVHGGMTLKDINQKIRNPPAKPKAHIEEPAVIQTSAFSGKPVVGKTKIRTEGGKGSITIMRTRG", "length": 300, "molWeight": 33719, "crc64": "23B32F668BDB6FEA", "md5": "A5AB88EEA6BE8023C8DEA6F4DBF87E1B"}}
{"primaryAccession": "Q6NPM8", "text": "This is Bifunctional phosphatase IMPL2, chloroplastic protein, from Mouse-ear cress, contains 346 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6NPM8", "organism_name": "Mouse-ear cress", "protein_name": "Bifunctional phosphatase IMPL2, chloroplastic", "length": 346, "firstPublicDate": "2009-09-22", "FUNCTION": "Phosphatase required for histidine production, Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the inositol monophosphatase superfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLAQSHFFSKSFDLIPPQSPALRSANPSLRISSSYSNSRLSFLSSSAIAVPVSRRRFCLTMASNSKRPNISNESPSELSDTELDRFAAVGNALADASGEVIRKYFRKKFDIVDKDDMSPVTIADQMAEEAMVSIIFQNLPSHAIYGEEKGWRCKEESADYVWVLDPIDGTKSFITGKPVFGTLIALLYKGKPILGLIDQPILKERWIGMNGRRTKLNGEDISTRSCPKLSQAYLYTTSPHLFSEEAEKAYSRVRDKVKVPLYGCDCYAYALLASGFVDLVIESGLKPYDFLALVPVIEGAGGTITDWTGKRFLWEASSSAVATSFNVVAAGDSDIHQQALESLEWH", "length": 346, "molWeight": 38235, "crc64": "2DA4939BB947517E", "md5": "1B4897A5816A7102170481EFFF229DC5"}}
{"primaryAccession": "Q6NQ88", "text": "This is Protein DAMAGED DNA-BINDING 2 protein, from Mouse-ear cress, contains 557 amino acids, has 1 CCHC-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [100, 117], "description": "CCHC-type", "keyword_description": "Zinc finger", "textural_description": "CCHC-type Zinc finger"}], "meta_data": {"primaryAccession": "Q6NQ88", "organism_name": "Mouse-ear cress", "protein_name": "Protein DAMAGED DNA-BINDING 2", "length": 557, "firstPublicDate": "2008-02-26", "FUNCTION": "May function as the substrate recognition module for a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex including DDB1A and CUL4 (By similarity), Required for DNA repair, Binds to DDB1A to form the UV-damaged DNA-binding protein complex (the UV-DDB complex), The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair (PubMed:18551167), Involved in UV-B tolerance and genome integrity, In association with ATCSA-1, is necessary for repair of UV-B-induced DNA lesions (PubMed:20128879)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WD repeat DDB2/WDR76 family", "domain_description": {"CCHC-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSTRSRRKRDPEIVIARDTDSELSSSEEEEEEEDNYPFSESEEEDEAVKNGGKIELEKNKAKGKAPITVKLIKKVCKVCKQPGHEAGFKGATYIDCPMKPCFLCKMPGHTTMSCPHRVVTDHGILPTSHRNTKNPIDFVFKRQLQPRIPPIKPKYVIPDQVHCAVIRYHSRRVTCLEFHPTKNNILLSGDKKGQIGVWDFGKVYEKNVYGNIHSVQVNNMRFSPTNDDMVYSASSDGTIGYTDLETGTSSTLLNLNPDGWQGANSWKMLYGMDINSEKGVVLAADNFGFLHMIDHRTNNSTGEPILIHKQGSKVCGLDCNPVQPELLLSCGNDHFARIWDMRKLQPKASLHDLAHKRVVNSAYFSPSSGTKILTTCQDNRIRIWDSIFGNLDLPSREIVHSNDFNRHLTPFKAEWDPKDTSESLIVIGRYISENYNGTALHPIDFIDASNGQLVAEVMDPNITTITPVNKLHPRDDVLASGSSRSLFIWRPQDNTEMVEEKKDKKIIICYGDSKKKGKKQKRGSDDEDDEDDIFSSKGKNIKVNKYQAKTTKKTKT", "length": 557, "molWeight": 62829, "crc64": "5C4C32E25166D7C0", "md5": "09D0316A15A8CF870708FF9A1A9F3E4E"}}
{"primaryAccession": "Q6NQ99", "text": "This is Protein POLAR LOCALIZATION DURING ASYMMETRIC DIVISION AND REDISTRIBUTION protein, from Mouse-ear cress, contains 344 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6NQ99", "organism_name": "Mouse-ear cress", "protein_name": "Protein POLAR LOCALIZATION DURING ASYMMETRIC DIVISION AND REDISTRIBUTION", "length": 344, "firstPublicDate": "2014-06-11", "FUNCTION": "Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells (PubMed:21963668), Acts as a stomatal lineage scaffold which regulates subcellular localization and transient polarization of kinases (e,g, ASK7/BIN2 and ASK3/SK12) involved in ACD in a BASL-dependent manner (PubMed:30429609), Promotes the differentiation of both pavement cells and stomata (PubMed:30429609)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEGSRRRRGDGCTIVQCYTPRRFVGRWLSGLRSSKGKRDAGEEQEDDTRRYQLAPIRCSTSLNQLVMQDNKQNCRLNKSKEPETNTFESQSRESPLEVGIGSFLLYLVVASKTELDKMTNLRMQMEMFLLNAKEQLQKKDTPMSSNEASGFQFSPQEFSNLASSIFQESSSSVLQEEYTEFEVSEPEDYRRGTDCNSKLQAEVGRLPLGEKAEDRQTKHQIQRQCKLKDNEVTKSHIPEMVVSDERYGVCPYELDKKLHELLETRQQEELVKLETALNRVERRLQEKETEVSWWKDAARLLAQRVPESSRSGLEWCNPDSSTCSERSVPRSYEACSIHRTSFSR", "length": 344, "molWeight": 39765, "crc64": "B1302BDD737465B1", "md5": "1FBC2B81FDB9027A34BA09A60B287AD8"}}
{"primaryAccession": "Q6NSW7", "text": "This is Homeobox protein NANOGP8 protein, from Human, contains 305 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6NSW7", "organism_name": "Human", "protein_name": "Homeobox protein NANOGP8", "length": 305, "firstPublicDate": "2006-11-28", "FUNCTION": "May act as a transcription regulator (By similarity), When overexpressed, promotes entry of cells into S phase and cell proliferation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Nanog homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVDPACPQSLPCFEESDCKESSPMPVICGPEENYPSLQMSSAEMPHTETVSPLPSSMDLLIQDSPDSSTSPKGKQPTSAENSVAKKEDKVPVKKQKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRWQKNNWPKNSNGVTQKASAPTYPSLYSSYHQGCLVNPTGNLPMWSNQTWNNSTWSNQTQNIQSWSNHSWNTQTWCTQSWNNQAWNSPFYNCGEESLQSCMHFQPNSPASDLEAALEAAGEGLNVIQQTTRYFSTPQTMDLFLNYSMNMQPEDV", "length": 305, "molWeight": 34673, "crc64": "C59ECF476A600EB0", "md5": "C9CECAA95C62FA5643C321DB0BB5D0FA"}}
{"primaryAccession": "Q6NUK1", "text": "This is Mitochondrial adenyl nucleotide antiporter SLC25A24 protein, from Human, contains 477 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6NUK1", "organism_name": "Human", "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "length": 477, "firstPublicDate": "2008-02-05", "FUNCTION": "Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane, Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter, By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways (PubMed:15123600, PubMed:22015608), In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides (PubMed:15123600), May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates (PubMed:22015608, PubMed:29100093)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRWLRDFVLPTAACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK", "length": 477, "molWeight": 53354, "crc64": "F533D47B2457123F", "md5": "80F3BF7F99CF71FFBA3027DE669CF07D"}}
{"primaryAccession": "Q6NVG5", "text": "This is Melanoregulin protein, from Mouse, contains 214 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6NVG5", "organism_name": "Mouse", "protein_name": "Melanoregulin", "length": 214, "firstPublicDate": "2007-06-26", "FUNCTION": "Probably functions as cargo-recognition protein that couples cytoplasmic vesicles to the transport machinery (PubMed:22940130, PubMed:22275436, PubMed:30174147), Plays a role in hair pigmentation, a process that involves shedding of melanosome-containing vesicles from melanocytes, followed by phagocytosis of the melanosome-containing vesicles by keratinocytes (PubMed:15550542, PubMed:3410303, PubMed:22753477), Functions on melanosomes as receptor for RILP and the complex formed by RILP and DCTN1, and thereby contributes to retrograde melanosome transport from the cell periphery to the center (PubMed:22940130, PubMed:22275436), Overexpression causes accumulation of late endosomes and/or lysosomes at the microtubule organising center (MTOC) at the center of the cell (PubMed:19240024, PubMed:30174147), Probably binds cholesterol and requires the presence of cholesterol in membranes to function in microtubule-mediated retrograde organelle transport (PubMed:30174147), Binds phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate and phosphatidylinositol 3,5-bisphosphate, but not phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 4,5-bisphosphate (PubMed:19240024), Required for normal phagosome clearing and normal activation of lysosomal enzymes in lysosomes from retinal pigment epithelium cells (PubMed:19240024), Required for normal degradation of the lipofuscin component N-retinylidene-N-retinylethanolamine (A2E) in the eye (PubMed:19240024), May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (Probable)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the melanoregulin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGLRRWLRSACCCCPCRCLEEPARPEKEPLVSGNNPYSSFGATLERDDEKNLWSMPHDVSHTEADDDRILYNLIVIRNQQTKDSEEWQRLNYDIYTLRQIRREVRNRWRRILEDLGFQREADSLLSVTKLSTMSDSKNTRKAREMLLKLAEETSIFPASWELSERYLLVVDRLIALDAAEDFFKIASQMYPKKPGVPCLVDGQRKLHCLPFPSP", "length": 214, "molWeight": 25010, "crc64": "07537592C78CF050", "md5": "AC6BB4F90521E15DBA9D128046E513B1"}}
{"primaryAccession": "Q6NWY9", "text": "This is Pre-mRNA-processing factor 40 homolog B protein, from Human, contains 871 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6NWY9", "organism_name": "Human", "protein_name": "Pre-mRNA-processing factor 40 homolog B", "length": 871, "firstPublicDate": "2007-11-13", "FUNCTION": "May be involved in pre-mRNA splicing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the PRPF40 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMPPPFMPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQLDDHQ", "length": 871, "molWeight": 99358, "crc64": "BB62C95BEFB9D23A", "md5": "2C919B8A393F3D005C599A0E680689C3"}}
{"primaryAccession": "Q6P050", "text": "This is F-box and leucine-rich protein 22 protein, from Human, contains 247 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6P050", "organism_name": "Human", "protein_name": "F-box and leucine-rich protein 22", "length": 247, "firstPublicDate": "2006-07-25", "FUNCTION": "Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, Promotes ubiquitination of sarcomeric proteins alpha-actinin-2 (ACTN2) and filamin-C (FLNC)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MWPLLTMHITQLNRECLLHLFSFLDKDSRKSLARTCSQLHDVFEDPALWSLLHFRSLTELQKDNFLLGPALRSLSICWHSSRVQVCSIEDWLKSAFQRSICSRHESLVNDFLLRVCDRLSAVRSPRRREAPAPSSGTPIAVGPKSPRWGGPDHSEFADLRSGVTGARAAARRGLGSLRAERPSETPPAPGVSWGPPPPGAPVVISVKQEEGKQGRTGRRSHRAAPPCGFARTRVCPPTFPGADAFPQ", "length": 247, "molWeight": 27269, "crc64": "9966D98688B8FF26", "md5": "470E2A81984CE2D5DC29C72DB1C5AC70"}}
{"primaryAccession": "Q6PEH4", "text": "This is U3 small nucleolar RNA-associated protein 25 homolog protein, from Zebrafish, contains 753 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6PEH4", "organism_name": "Zebrafish", "protein_name": "U3 small nucleolar RNA-associated protein 25 homolog", "length": 753, "firstPublicDate": "2006-10-31", "FUNCTION": "Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (PubMed:28263972), Essential for embryonic development in part through the regulation of p53 pathway, Required for the expansion growth of intestine, liver and exocrine pancreas, but not endocrine pancreas, May not play a major role during the early stage of endodermal organogenesis, Also involved in the sympathetic neuronal development (PubMed:28263972), Triggers the degradation of p53/TP53 and Delta113p53 isoform in a ubiquitination pathway independent way (PubMed:23357851), Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53 (PubMed:23357851, PubMed:27657329)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the UTP25 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGKRRRGKQEIDNLTKKQKKHLKEFGEQHPFHDKVVERPEKTQILRLPDSPQRPEPDSEDDSDAEQPSAYQKLLSTMIQGDEDDVESEDEESEEEDNEEEAEVEGDSEEEVEDTDEEDGNDAEEVLEDKVEETSDKLQKKHPEKTNGDVEENEEAEMEGEFTDKKNEAAFCLETNMPAEGEENTAQQEQDEDMFVKHQEIELSEEEVGRISQGSKVKTQVKWAKLGVLQCMCPLERFPAIGQASSAPLPPIHKTLEANWHLLNLPFGAATDVTELQKEMLGLMGTYRDLYLANLSPLKEAKEVRSAYCLHALNHVLKANSRVLRNNAKLKESKNGDEDFRDQGLTRPKVLILVPFRDGALRVVQTFMTLLEPKGKKTDASNKKRFKEEYGEETDEKPPNLQRPDDYHAVFSGNIDDHFRIGMSILRHSMRLYAPFYSSDIIIASPLGLRTVLGAEGEKKRDHDFLSSIELLIVDQADVFLMQNWEHLLHVLEHLNLQPLDSHGVDFSRVRMWNLNNWAAYYRQTLVFSAIQEPQITNILTKHCHNYRGQVCSKTIPKIGSICQVLVQLPHVFQMFHSDSFMDQDARFQFFVDKILPQYRDSVMSHTFIYVPSYFDFVRLRNYLKKEDVSFANISEYSQRSEVSRARHYFQKGEKQFLLFSERFHFYKRYTIKGIHNLIFYGLPTYPHFYSEVCNMLQAGVREGGASVSFTCTALYSRYDVHRLAAITGADRAAQMLQSKKTTHLFITGEEKST", "length": 753, "molWeight": 86802, "crc64": "9B71909685860B10", "md5": "7AABADE9FEFF0BFDB1A79986D76918A6"}}
{"primaryAccession": "Q6PGG6", "text": "This is Guanine nucleotide-binding protein-like 3-like protein protein, from Mouse, contains 577 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6PGG6", "organism_name": "Mouse", "protein_name": "Guanine nucleotide-binding protein-like 3-like protein", "length": 577, "firstPublicDate": "2007-04-17", "FUNCTION": "Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML, Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation, Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase, Required for cell proliferation, By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition, Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation, By acting on MDM2, may affect TP53 activity, Required for normal processing of ribosomal pre-rRNA, Binds GTP (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TRAFAC class YlqF/YawG GTPase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMKIRHKNKKPGKGSKGCKKPARQNGKKVTSRPSSAPQIVHGNDHASREAELKKKRVEEMREKQQVAREQERQRHRTMESYCQDVLKRQQEFEQKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEETVLRAEGNKKLVLVLNKIDLVPKEIVEKWLEYLLNELPTVAFKASTQHHQVKNLTRCKVPVDQASESLLKSRACFGAENLMRVLGNYCRLGEVRGHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGVTKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCIHVQKLADPVTPVETILQRCNLEEISSYYGVSGFQTTEHFLTAVAHRLGKKKKGGVYSQEQAAKAVLADWVSGKISFYTLPPPTHTLPTHLSAEIVKEMTEVFDIEDTEHANEDTMECLAVGESDELLGDMDPQEMEVRWLHSPLVKIADAIENRSTVYKIGNLTGYCTKPNRNQMGWPKRNVDHHCPQNNRVVEVSSVDRRPMLQRILETDPLQQGQALASALKNKKKLQKRSDKIATKLSDSMMSMLDLSGNSDDCAGD", "length": 577, "molWeight": 65195, "crc64": "C2F6E1FE5EED9815", "md5": "BB2575AFC26B6ACA65EE7A3E1DFA8FC0"}}
{"primaryAccession": "Q6PHR2", "text": "This is Serine/threonine-protein kinase ULK3 protein, from Human, contains 472 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6PHR2", "organism_name": "Human", "protein_name": "Serine/threonine-protein kinase ULK3", "length": 472, "firstPublicDate": "2006-09-19", "FUNCTION": "Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy, Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3), Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation, Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently, Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAGPGWGPPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAHPWVDLEHMPSGESLGRATALVVQAVKKDQEGDSAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNQALLRQGTSARDLLREMARDKPRLLAALEVASAAMAKEEAAGGEQDALDLYQHSLGELLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKMRESRWEADTLDKEGLSESVRSSCTLQ", "length": 472, "molWeight": 53444, "crc64": "11D03E311AF36162", "md5": "D173F13ECC581085B0AE5D8128BA1603"}}
{"primaryAccession": "Q6PIW4", "text": "This is Fidgetin-like protein 1 protein, from Human, contains 674 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6PIW4", "organism_name": "Human", "protein_name": "Fidgetin-like protein 1", "length": 674, "firstPublicDate": "2007-09-11", "FUNCTION": "Involved in DNA double-strand break (DBS) repair via homologous recombination (HR), Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner, May regulate osteoblast proliferation and differentiation (PubMed:23754376), May play a role in the control of male meiosis dynamic (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the AAA ATPase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQTSSSRSVHLSEWQKNYFAITSGICTGPKADAYRAQILRIQYAWANSEISQVCATKLFKKYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQAGKKFKDSLLEPALASVVIHKEATVFDLPKFSVCGSSQESDSLPNSAHDRDRTQDFPESNRLKLLQNAQPPMVTNTARTCPTFSAPVGESATAKFHVTPLFGNVKKENHSSAKENIGLNVFLSNQSCFPAACENPQRKSFYGSGTIDALSNPILNKACSKTEDNGPKEDSSLPTFKTAKEQLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKPYGAGPTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK", "length": 674, "molWeight": 74077, "crc64": "2EB812B407495BF2", "md5": "F4BC046E8A24D63514BAEF66BE98FB54"}}
{"primaryAccession": "Q6PIZ9", "text": "This is T-cell receptor-associated transmembrane adapter 1 protein, from Human, contains 186 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6PIZ9", "organism_name": "Human", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "length": 186, "firstPublicDate": "2005-12-20", "FUNCTION": "Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSGISGCPFFLWGLLALLGLALVISLIFNISHYVEKQRQDKMYSYSSDHTRVDEYYIEDTPIYGNLDDMISEPMDENCYEQMKARPEKSVNKMQEATPSAQATNETQMCYASLDHSVKGKRRKPRKQNTHFSDKDGDEQLHAIDASVSKTTLVDSFSPESQAVEENIHDDPIRLFGLIRAKREPIN", "length": 186, "molWeight": 21211, "crc64": "236A4BEFF427EA3E", "md5": "664948AEFD85C0DB633689D9DAF23860"}}
{"primaryAccession": "Q6PQK2", "text": "This is Nitrophorin-7 protein, from Triatomid bug, contains 205 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6PQK2", "organism_name": "Triatomid bug", "protein_name": "Nitrophorin-7", "length": 205, "firstPublicDate": "2009-10-13", "FUNCTION": "Converts nitrite as the sole substrate to form nitric oxide gas (NO), NO(2-) serves both as an electron donor and as an electron acceptor, Binds to negatively charged cell surfaces of activated platelets; binds to L-a-phosphatidyl-L-serine (PS)-bearing phospholipid membranes, Once bound on an activated platelet, NP7 releases its stored nitric oxide gas (NO) into the victim's tissues while feeding, resulting in vasodilation and inhibition of platelet aggregation, Also acts as an anticoagulant by blocking coagulation-factor binding sites, Has antihistamine activity; binds histamine with high affinity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the calycin superfamily, Nitrophorin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MELYTALLAVTILSPSSIVGLPGECSVNVIPKKNLDKAKFFSGTWYETHYLDMDPQATEKFCFSFAPRESGGTVKEALYHFNVDSKVSFYNTGTGPLESNGAKYTAKFNTVDKKGKEIKPADEKYSYTVTVIEAAKQSALIHICLQEDGKDIGDLYSVLNRNKNALPNKKIKKALNKVSLVLTKFVVTKDLDCKYDDKFLSSWQK", "length": 205, "molWeight": 22901, "crc64": "8846C9FB8141F2D2", "md5": "ABF22780F49A9D365F5BF247439293F0"}}
{"primaryAccession": "Q6R567", "text": "This is E3 ubiquitin-protein ligase RMA1H1 protein, from Capsicum pepper, contains 252 amino acids, has 1 RING-type Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [41, 90], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q6R567", "organism_name": "Capsicum pepper", "protein_name": "E3 ubiquitin-protein ligase RMA1H1", "length": 252, "firstPublicDate": "2010-07-13", "FUNCTION": "E3 ubiquitin-protein ligase required for aquaporin levels regulation", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNQDMALEQLDTTFNKHDTPLGKWKSMNDEVEENISGGFDCNICLDCVHEPVITLCGHLYCWPCIYKWIYFQSVSSENSDQQQPQCPVCKAEVSEKTLIPLYGRGGQSTKPSEGKAPNLGIVIPQRPPSPRCGGHFLLPTTDSNPSQLLQRRGYQQQSQTRQPAYQGSYMSSPMLSPGGATANMLQHSMIGEVAYARIFGNSSTTMYTYPNSYNLAISSSPRMRRQLSQADRSLGRICFFLFCCFVTCLILF", "length": 252, "molWeight": 28211, "crc64": "D05AE7113CEBAE49", "md5": "25EF447AE99EBA058067F43A6C5B352E"}}
{"primaryAccession": "Q6SJQ0", "text": "This is CMRF35-like molecule 8 protein, from Mouse, contains 318 amino acids, has 1 Ig-like V-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [28, 129], "description": "Ig-like V-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like V-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "Q6SJQ0", "organism_name": "Mouse", "protein_name": "CMRF35-like molecule 8", "length": 318, "firstPublicDate": "2008-02-26", "FUNCTION": "Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:12874256, PubMed:12893283, PubMed:16339535), Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the CD300 family", "domain_description": {"Ig-like V-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTQLASAVWLPTLLLLLLLFWLPGCVPLHGPSTMSGSVGESLSVSCRYEEKFKTKDKYWCRVSLKILCKDIVKTSSSEEARSGRVTIRDHPDNLTFTVTYESLTLEDADTYMCAVDISLFDGSLGFDKYFKIELSVVPSEDPVSSPGPTLETPVVSTSLPTKGPALGSNTEGHREHDYSQGLRLPALLSVLALLLFLLVGTSLLAWRMFQKRLVKADRHPELSQNLRQASEQNECQYVNLQLHTWSLREEPVLPSQVEVVEYSTLALPQEELHYSSVAFNSQRQDSHANGDSLHQPQDQKAEYSEIQKPRKGLSDLYL", "length": 318, "molWeight": 35629, "crc64": "490EDBD46AF0A7C6", "md5": "AC132E23134C6D6B726E315C8E17941A"}}
{"primaryAccession": "Q6STE5", "text": "This is SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 protein, from Human, contains 483 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6STE5", "organism_name": "Human", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "length": 483, "firstPublicDate": "2005-01-04", "FUNCTION": "Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology), Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner, Stimulates nuclear receptor mediated transcription, Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex), During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state, The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes, As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF), The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells, The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SMARCD family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAADEVAGGARKATKSKLFEFLVHGVRPGMPSGARMPHQGAPMGPPGSPYMGSPAVRPGLAPAGMEPARKRAAPPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIASWELRVEGKLLDDPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT", "length": 483, "molWeight": 55016, "crc64": "B7B28DD11DCD0B5C", "md5": "8A9EAFA6009DF3B68C2802A87B9FD7AE"}}
{"primaryAccession": "Q6UPR8", "text": "This is Endoplasmic reticulum metallopeptidase 1 protein, from Rat, contains 898 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6UPR8", "organism_name": "Rat", "protein_name": "Endoplasmic reticulum metallopeptidase 1", "length": 898, "firstPublicDate": "2006-10-31", "FUNCTION": "Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the peptidase M28 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEWSSESAAVRRHRGTAERREGQAAASHPQREASAQEDARGGGRMRGRTESGGESRGAKTALSEARTALALALYLLALRALVQLSLQRLVLSRTSGLQGEFDARQARVYLEHITAIGPRTTGSAENEILTVQYLLEQITLIEEQSNSLHRISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPQDGAKYAVLANCHFDSVANSPGASDDAVSCAVMLEVLRVMAASPEPLQHAVVFLFNGAEENVLQASHGFITQHPWASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILIDSIQRAGDNILAVLKYLATSDMLASSSEYRHGSMVFFDVLGLLVIAYPSRVGSIINYMVVMAVVLYLGRKLLRPNHSNSNYVRDFLCGLGITFISWFTSLVTVLIIAVFVSLIGQSLSWYNYFYIAVCLYGTATVAKIILIHTLAKRFYYVNASDLYLGELFFDTSLFVHCGFLVALTAQGFCSAFMSAVWVAFPLLTKLCVYKDFKKHGAKGRFIALYLLGMFIPYLYGLYLIWAVFEMFTPILGRSGSEIPPDVVLASILAVCVMILSSYFITFIYLVNSTKKTILTLILVCAVTFLLVCSGAFFPYSSNPDSPKPKRVFLQHVSRTFHNLEGSVVKRDSGIWINGFDYTGMSHVTPHIPEINDTIRAHCEENAPLCGFPWYLPVHFLIRKNWYLPAPEISPRNPAHFRLVSKEKMPWDSIKLTFEATGPSHMSFYVRTHKGSTLSQWSLGNGIPVTSRGGDYFVFYSHGLQASAWQFWIEVQVSEEQPEGMVTVAIAAHYLSGENKRSSQLDALKEKFPDWSFPSAWVSTYSLFVF", "length": 898, "molWeight": 99897, "crc64": "EF1E574C8BFAD1F3", "md5": "C8548BA8D1179DDEC853970400096BFB"}}
{"primaryAccession": "Q6UW78", "text": "This is Ubiquinol-cytochrome-c reductase complex assembly factor 3 protein, from Human, contains 93 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6UW78", "organism_name": "Human", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "length": 93, "firstPublicDate": "2004-11-23", "FUNCTION": "Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex, Thereby, plays an important role in ATP production by mitochondria, Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the UQCC3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDSLRKMLISVAMLGAGAGVGYALLVIVTPGERRKQEMLKEMPLQDPRSREEAARTQQLLLATLQEAATTQENVAWRKNWMVGGEGGAGGRSP", "length": 93, "molWeight": 10081, "crc64": "7E65D81280196F93", "md5": "89AC08C7C8F62C47A211B14D15454D13"}}
{"primaryAccession": "Q6UXZ4", "text": "This is Netrin receptor UNC5D protein, from Human, contains 953 amino acids, has 1 Ig-like Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [54, 151], "description": "Ig-like", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like Immunoglobulin domain"}, {"location": [153, 244], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "Q6UXZ4", "organism_name": "Human", "protein_name": "Netrin receptor UNC5D", "length": 953, "firstPublicDate": "2004-10-11", "FUNCTION": "Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity), Plays a role in cell-cell adhesion and cell guidance, Receptor for netrin involved in cell migration, Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity), May play a role in apoptosis in response to DNA damage (PubMed:24691657), It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:24519068), Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the unc-5 family", "domain_description": {"Ig-like Immunoglobulin domain": 1, "Ig-like C2-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGRAAATAGGGGGARRWLPWLGLCFWAAGTAAARGTDNGEALPESIPSAPGTLPHFIEEPDDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQSIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSQSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNSAMQPDLTVSRTYSGPICLQDPLDKELMTESSLFNPLSDIKVKVQSSFMVSLGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSEVLLSPEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQHDGDLDSLACALEEIGRTHTKLSNISESQLDEADFNYSRQNGL", "length": 953, "molWeight": 105880, "crc64": "5F893B9DF746F731", "md5": "0BA9717760B57171D9C958B97617E83A"}}
{"primaryAccession": "Q6X4U4", "text": "This is Sclerostin domain-containing protein 1 protein, from Human, contains 206 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6X4U4", "organism_name": "Human", "protein_name": "Sclerostin domain-containing protein 1", "length": 206, "firstPublicDate": "2005-03-29", "FUNCTION": "May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity), Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the sclerostin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLPPAIHFYLLPLACILMKSCLAFKNDATEILYSHVVKPVPAHPSSNSTLNQARNGGRHFSNTGLDRNTRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESMSPAKPVQHHRERKRASKSSKHSMS", "length": 206, "molWeight": 23307, "crc64": "9FB3CC41E4B53834", "md5": "98C5A84EF7AAEADD042E45432BE2C6E5"}}
{"primaryAccession": "Q6XE24", "text": "This is RNA-binding motif, single-stranded-interacting protein 3 protein, from Human, contains 437 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6XE24", "organism_name": "Human", "protein_name": "RNA-binding motif, single-stranded-interacting protein 3", "length": 437, "firstPublicDate": "2007-02-06", "FUNCTION": "Binds poly(A) and poly(U) oligoribonucleotides", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGKRLDQPQMYPQYTYYYPHYLQTKQSYAPAPHPMAPPSPSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAAIQNGFYSSPYSIATNRMIPQTSITPFIAASPVSTYQVQSTSWMPHPPYVMQPTGAVITPTMDHPMSMQPANMMGPLTQQMNHLSLGTTGTIQSQDRIMILHQLLCQYMTAAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDTSGQQQQIAVDTSNEHAPAYSYQQSKP", "length": 437, "molWeight": 47840, "crc64": "7EFC2ECFE24E323C", "md5": "F7BD8F333EC51B26F20893816976ACC2"}}
{"primaryAccession": "Q6ZP29", "text": "This is Lysosomal amino acid transporter 1 homolog protein, from Human, contains 291 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6ZP29", "organism_name": "Human", "protein_name": "Lysosomal amino acid transporter 1 homolog", "length": 291, "firstPublicDate": "2007-04-03", "FUNCTION": "Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the laat-1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVWKKLGSRNFSSCPSGSIQWIWDVLGECAQDGWDEASVGLGLISILCFAASTFPQFIKAYKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRPSLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSEGSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS", "length": 291, "molWeight": 31947, "crc64": "B544D3BFA5458920", "md5": "053794D3B846850D20849E37FB97330F"}}
{"primaryAccession": "Q6ZWS8", "text": "This is Speckle-type POZ protein protein, from Mouse, contains 374 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6ZWS8", "organism_name": "Mouse", "protein_name": "Speckle-type POZ protein", "length": 374, "firstPublicDate": "2004-09-27", "FUNCTION": "Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation, The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL (By similarity), In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3, In complex with CUL3, involved in ubiquitination of MACROH2A1 and BMI1; this does not lead to their proteasomal degradation, Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation, Involved in the regulation of bromodomain and extra-terminal motif (BET) proteins BRD2, BRD3, BRD4 stability (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Tdpoz family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS", "length": 374, "molWeight": 42132, "crc64": "EE5F4C5CF6FD09DC", "md5": "26AD33307E9D9E0F62E843DC946CBA41"}}
{"primaryAccession": "Q715S9", "text": "This is Thioredoxin domain-containing protein 3 protein, from Rat, contains 587 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q715S9", "organism_name": "Rat", "protein_name": "Thioredoxin domain-containing protein 3", "length": 587, "firstPublicDate": "2005-07-05", "FUNCTION": "Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs, May be involved in the reduction of disulfide bonds within the sperm FS components, In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "In the C-terminal section; belongs to the NDK family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASKKREVQLQSVVNSQNLWDEMLLNKGLTVIDVYQAWCGPCKAVQALFRKLKNELNEDELLHFVVAEADSIVTLQPFRDKCEPVFLFSLNGKIIAKIQGANAPLINRKVIALIDEEKKIAAGEMARPQYVEIPLVDSLDEEYGEVHYESNVEVYNMAVINPDAVLMRKNLEIKEKITKEGFIIEIQENMLLPEEVAREFYNHMIDEPDFEEFVYSMTNRLSCVLIISQGEDTEVIEEEALPQSDDEEEPDPLEEPHVRFAPMLVKKKRDSLQEYMDRQHMSDYCHVEDDAVKVSKFIDILFPDFKTMKSTNVQRTLGLLYPEVCEEEKDNVLDIIQNEGFTILMQRQVVLSEEEARAVCHVHEDEDYFDNLIGYMCSNNSYILVLMREHSVERWKELIGPKTVEEAYASHPDSLCVRFASGNFPVNQFYGSSSKAAAETEIEHFFPPQSTLALIKPHVSHKERMEILKAIRDARFELTQMKEMHLTPEHASKVYFKITGKDFYKNVLDVLSSGMSVVMILTKWNAVGEWRRMMGPVDPEEAKLLSPNSLRARYGIDVLRNAVHGASNMSEAATAISNVFTESNFEN", "length": 587, "molWeight": 67312, "crc64": "7FC3D94DFCE19F4B", "md5": "64DDC55B7411DAA20ECC4F7E961C6D03"}}
{"primaryAccession": "Q715T0", "text": "This is Thioredoxin domain-containing protein 3 protein, from Mouse, contains 586 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q715T0", "organism_name": "Mouse", "protein_name": "Thioredoxin domain-containing protein 3", "length": 586, "firstPublicDate": "2005-07-05", "FUNCTION": "Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs, May be involved in the reduction of disulfide bonds within the sperm FS components, In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "In the C-terminal section; belongs to the NDK family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASKKREVQLQSVVNSQNLWDEMLLNKGLTVIDVYQAWCGPCKAVQSLFRKLKNELNEDEILHFVVAEADNIVTLQPFRDKCEPVFLFSLNGKIIAKIQGANAPLINRKVITLIDEERKIVAGEMDRPQYVEIPLVDAIDEEYGEVQYESAAEVYNMAIIKPDAVLMRKNIEVREKIAKEGFVIEIQENLILPEEVVREFYTHIADQPDFEEFVVSMTNGLSCVLIVSQEDSEVIQEETLPQTDTEEEPGVLEEPHVRFAPVMIKKKRDSLQEYMDRQHMSDYCDVEDDAVKVSKLIDILFPDFKTMKSTNVQTTLALLHPDICEEEKDDVLNVIHNEGFTILMQRQIVLSEEEARTVCKIHENEEYFDNLIGHMTSNHSYVLALRRENGVEYWKTLIGPKTIEEAYASHPQSLCVQFASGNFPTNQFYGSSSKAAAEKEIAHFFPPQSTLALIKPHVTHKERMEILKTIKEAGFELTLMKEMHLTPEHANKIYFKITGKDFYKNVLEVLSLGMSLVMVLTKWNAVAEWRRMVGPVDPEEAKLLSPESLRAKYGLDILRNAVHGASNFSEASEIISNVFTEGNPEN", "length": 586, "molWeight": 66857, "crc64": "5679ED17A63F1991", "md5": "31CC15910808B447238C8CBE9FCA5B67"}}
{"primaryAccession": "Q76EJ3", "text": "This is UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter protein, from Human, contains 337 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q76EJ3", "organism_name": "Human", "protein_name": "UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter", "length": 337, "firstPublicDate": "2008-01-15", "FUNCTION": "Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars), May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the TPT transporter family, SLC35D subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTAGGQAEAEGAGGEPGAARLPSRVARLLSALFYGTCSFLIVLVNKALLTTYGFPSPIFLGIGQMAATIMILYVSKLNKIIHFPDFDKKIPVKLFPLPLLYVGNHISGLSSTSKLSLPMFTVLRKFTIPLTLLLETIILGKQYSLNIILSVFAIILGAFIAAGSDLAFNLEGYIFVFLNDIFTAANGVYTKQKMDPKELGKYGVLFYNACFMIIPTLIISVSTGDLQQATEFNQWKNVVFILQFLLSCFLGFLLMYSTVLCSYYNSALTTAVVGAIKNVSVAYIGILIGGDYIFSLLNFVGLNICMAGGLRYSFLTLSSQLKPKPVGEENICLDLKS", "length": 337, "molWeight": 36673, "crc64": "7895A9153A82BE5A", "md5": "DE58DC99660B90119DE6A0BCCF342599"}}
{"primaryAccession": "Q76MX4", "text": "This is Transcription factor MafG protein, from Rat, contains 189 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q76MX4", "organism_name": "Rat", "protein_name": "Transcription factor MafG", "length": 189, "firstPublicDate": "2009-04-14", "FUNCTION": "Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (By similarity), However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to specific DNA-binding sites (By similarity), Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor (By similarity), Transcription factor, component of erythroid-specific transcription factor NFE2L2 (By similarity), Activates globin gene expression when associated with NFE2L2 (By similarity), May be involved in signal transduction of extracellular H(+) (PubMed:11583919)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family, Maf subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTTPNKGNKALKVSGEAGLGVCWAGHSYSALTPCAVPLQVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIIQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQNFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS", "length": 189, "molWeight": 20533, "crc64": "65F5CF89284DC9D4", "md5": "3E9534C5B2F18B65FD53D07EF8719EDE"}}
{"primaryAccession": "Q7K1V5", "text": "This is Protein jagunal protein, from Fruit fly, contains 197 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7K1V5", "organism_name": "Fruit fly", "protein_name": "Protein jagunal", "length": 197, "firstPublicDate": "2008-01-15", "FUNCTION": "Required for endoplasmic reticulum organization and proper vesicular traffic during vitellogenesis, Required for oocyte and bristle growth", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the jagunal family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATRGGPMVAGTDGNDFEFRQRVAGTYQISLLNKSRLKYCIFFHALLFFVMLAKLTSDILDHLDIFVLEIEELEVPPPLWWEYVWAASLLTSFLGLSAARGNKVREMQKYMVAILLFAILPLFYCFAYYFSDVWEFATLDKSVELDETDIFVWRGYPYGVFWYAFCFVGFQVHGFTLYFAYNLVKAWKARTATRKFQ", "length": 197, "molWeight": 23036, "crc64": "0B4DF7CF8DA49B6C", "md5": "14B0E904991911EF8FADD62C3DBF6269"}}
{"primaryAccession": "Q7KRI2", "text": "This is Longitudinals lacking protein-like protein, from Fruit fly, contains 127 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7KRI2", "organism_name": "Fruit fly", "protein_name": "Longitudinals lacking protein-like", "length": 127, "firstPublicDate": "2005-08-16", "FUNCTION": "Required, together with Trl, for maintaining the repressed state of target genes including homeotic genes Scr and Ubx, May also be involved in the activation of homeotic genes, Binds to a DNA Polycomb response element (PRE) at the bithorax complex, Also binds to polytene chromosomes at several hundred sites, many of which are shared with Trl and ph-p, Required during embryonic development", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMSSDQQFFLKWNDFQTNMVTSFRHLRDEKSFTDVTLACEGQTCKAHKMVLSACSPYFKALLEENPSKHPIIILKDVSYIHLQAILEFMYAGEVNVSQEQLPAFLKTADRLKVKGLAETPSSIKREG", "length": 127, "molWeight": 14489, "crc64": "3D5DE2C4E2E06B2D", "md5": "75E9586F7FC981AAFD410D31CC7958D3"}}
{"primaryAccession": "Q7KRW1", "text": "This is Protein TRC8 homolog protein, from Fruit fly, contains 809 amino acids, has 1 RING-type; atypical Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [621, 659], "description": "RING-type; atypical", "keyword_description": "Zinc finger", "textural_description": "RING-type; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q7KRW1", "organism_name": "Fruit fly", "protein_name": "Protein TRC8 homolog", "length": 809, "firstPublicDate": "2005-12-06", "FUNCTION": "Plays a role in growth inhibition that is dependent upon COP9 signalosome subunits CSN5 and CSN6, May modulate signalosome levels or compartmentalization, Probably functions in the same or a related pathway to VHL during early midline development", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {"RING-type; atypical Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSVRTKVLGLVDVMMRVPPVMVIDEILKMDMGMQSWLYPDKDKASGALATPTEAPAVPSGQDPFTSIKELFSHMTTSAQSVLEQSIEKASEAAKTHGMLSSGFNSLMNELSKDQTLADVLSTTTVKFVLCVFAFLSAACIFMLWTRHLVMVYMFLTSLGLTFLSYWSNVSALALTERSPSMVEDLMSLNTTRLLDSGGVVMSLAPHLMAQWFMGMLFAYIHLGPRFEHVQRSMPIIFASPILLAMLPLPAKVVQHLPVVAVFTPIILTKITLMQSAMEASRTVYNGYQYAMNFVSNFGLSALIENEWQRLNVPNVLRVFWTIRLIQGGYALATTESDEPLDLMTATQKLLVDGCETMTAVLGMTGVISMFCHYIGRGFQWYLLTYDDEEKSLGTVSAVLFYILALQTGLTSLSPDKRFIRLCRNLCLLMTALLHFLHNIVSPILMSLSAARNPSRKRHVRALSVCAFLVVLSVSLLYHLWSQQSISTWLLAVTAFSVEVVVKVLVSLATYTLFLLDARRQFFWEKLDDYLYYVRAFGNSVEFCFGILLFINGAWILIFESAQNATGGGIRAIMMCIHAYFNIWCEARAGWSVFMKRRSAVHKISALPEATPAQLQAFDDVCAICYQEMYSAKITRCRHFFHGVCLRKWLYVQDRCPLCHEIMMYTDKADENAPEAEPAPAAQAEQPMRIYPRDDANNAAAQRRSPERAPVEASEQAPATSSSSAAATIGAEAVSAIVESAAAVGEARSLVSVASSSSATHRISASGSSDSSYMTASAQSPPPTATSAAAVATAAASNTTHMFRMSQDQQ", "length": 809, "molWeight": 89235, "crc64": "B61E172E80D05317", "md5": "3BDEBE4F2CD8B95FB7AF5E87D83E47BE"}}
{"primaryAccession": "Q7L0Y3", "text": "This is tRNA methyltransferase 10 homolog C protein, from Human, contains 403 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7L0Y3", "organism_name": "Human", "protein_name": "tRNA methyltransferase 10 homolog C", "length": 403, "firstPublicDate": "2007-11-13", "FUNCTION": "Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation (PubMed:18984158, PubMed:21593607, PubMed:23042678, PubMed:27132592), Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends (PubMed:18984158), Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity (PubMed:23042678, PubMed:29040705), The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; TRMT10C/MRPP1 acting as the catalytic N(1)-methyltransferase subunit (PubMed:23042678), The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3'-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme (PubMed:29040705), In addition to tRNA N(1)-methyltransferase activity, TRMT10C/MRPP1 also acts as a mRNA N(1)-methyltransferase by mediating methylation of adenosine residues at the N(1) position of MT-ND5 mRNA (PubMed:29072297), Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the class IV-like SAM-binding methyltransferase superfamily, TRM10 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAFLKMSVSVNFFRPFTRFLVPFTLHRKRNNLTILQRYMSSKIPAVTYPKNESTPPSEELELDKWKTTMKSSVQEECVSTISSSKDEDPLAATREFIEMWRLLGREVPEHITEEELKTLMECVSNTAKKKYLKYLYTKEKVKKARQIKKEMKAAAREEAKNIKLLETTEEDKQKNFLFLRLWDRNMDIAMGWKGAQAMQFGQPLVFDMAYENYMKRKELQNTVSQLLESEGWNRRNVDPFHIYFCNLKIDGALHRELVKRYQEKWDKLLLTSTEKSHVDLFPKDSIIYLTADSPNVMTTFRHDKVYVIGSFVDKSMQPGTSLAKAKRLNLATECLPLDKYLQWEIGNKNLTLDQMIRILLCLKNNGNWQEALQFVPKRKHTGFLEISQHSQEFINRLKKAKT", "length": 403, "molWeight": 47347, "crc64": "28CBD97B4114819F", "md5": "0F59BE088F63092B666D34FB64F23806"}}
{"primaryAccession": "Q7L266", "text": "This is Isoaspartyl peptidase/L-asparaginase protein, from Human, contains 308 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7L266", "organism_name": "Human", "protein_name": "Isoaspartyl peptidase/L-asparaginase", "length": 308, "firstPublicDate": "2007-10-02", "FUNCTION": "Has both L-asparaginase and beta-aspartyl peptidase activity, May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions, Is highly active with L-Asp beta-methyl ester, Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys, Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn, Likewise, has no activity toward glutamine", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the Ntn-hydrolase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNPIVVVHGGGAGPISKDRKERVHQGMVRAATVGYGILREGGSAVDAVEGAVVALEDDPEFNAGCGSVLNTNGEVEMDASIMDGKDLSAGAVSAVQCIANPIKLARLVMEKTPHCFLTDQGAAQFAAAMGVPEIPGEKLVTERNKKRLEKEKHEKGAQKTDCQKNLGTVGAVALDCKGNVAYATSTGGIVNKMVGRVGDSPCLGAGGYADNDIGAVSTTGHGESILKVNLARLTLFHIEQGKTVEEAADLSLGYMKSRVKGLGGLIVVSKTGDWVAKWTSTSMPWAAAKDGKLHFGIDPDDTTITDLP", "length": 308, "molWeight": 32055, "crc64": "84E3D6C2D1555B32", "md5": "9F40FB957737F700B629135B67B56F9E"}}
{"primaryAccession": "Q7L513", "text": "This is Fc receptor-like A protein, from Human, contains 359 amino acids, has 2 Ig-like C2-type Immunoglobulin domain, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [70, 159], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}, {"location": [170, 257], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "Q7L513", "organism_name": "Human", "protein_name": "Fc receptor-like A", "length": 359, "firstPublicDate": "2006-03-21", "FUNCTION": "May be implicated in B-cell differentiation and lymphomagenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"Ig-like C2-type Immunoglobulin domain": 2}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLGCVLMAWALYLSLGVLWVAQMLLAASFETLQCEGPVCTEESSCHTEDDLTDAREAGFQVKAYTFSEPFHLIVSYDWLILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRDGSALGPPGPNREFSITVVQKADSGHYHCSGIFQSPGPGIPETASVVAITVQELFPAPILRAVPSAEPQAGSPMTLSCQTKLPLQRSAARLLFSFYKDGRIVQSRGLSSEFQIPTASEDHSGSYWCEAATEDNQVWKQSPQLEIRVQGASSSAAPPTLNPAPQKSAAPGTAPEEAPGPLPPPPTPSSEDPGFSSPLGMPDPHLYHQMGLLLKHMQDVRVLLGHLLMELRELSGHRKPGTTKATAE", "length": 359, "molWeight": 38927, "crc64": "76821DADB121499F", "md5": "8E590FA0B5E29938FDFE998450515DAE"}}
{"primaryAccession": "Q7L5A8", "text": "This is Fatty acid 2-hydroxylase protein, from Human, contains 372 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7L5A8", "organism_name": "Human", "protein_name": "Fatty acid 2-hydroxylase", "length": 372, "firstPublicDate": "2007-12-04", "FUNCTION": "Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis (PubMed:15337768, PubMed:15863841, PubMed:17355976, PubMed:22517924), FA2H is stereospecific for the production of (R)-2-hydroxy fatty acids (PubMed:22517924), Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath (By similarity), Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier (PubMed:17355976), Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis (By similarity), Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the sterol desaturase family, SCS7 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPAPPPAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHSANARRWLEQYYVGELRGEQQGSMENEPVALEETQKTDPAMEPRFKVVDWDKDLVDWRKPLLWQVGHLGEKYDEWVHQPVTRPIRLFHSDLIEGLSKTVWYSVPIIWVPLVLYLSWSYYRTFAQGNVRLFTSFTTEYTVAVPKSMFPGLFMLGTFLWSLIEYLIHRFLFHMKPPSDSYYLIMLHFVMHGQHHKAPFDGSRLVFPPVPASLVIGVFYLCMQLILPEAVGGTVFAGGLLGYVLYDMTHYYLHFGSPHKGSYLYSLKAHHVKHHFAHQKSGFGISTKLWDYCFHTLTPEKPHLKTQ", "length": 372, "molWeight": 42791, "crc64": "3F56B4C689B317BE", "md5": "1EF16D966D3E1BE8E7639D8C1C600FE8"}}
{"primaryAccession": "Q7M6Y5", "text": "This is Deuterosome assembly protein 1 protein, from Mouse, contains 601 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7M6Y5", "organism_name": "Mouse", "protein_name": "Deuterosome assembly protein 1", "length": 601, "firstPublicDate": "2007-08-21", "FUNCTION": "Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells, Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles, Probably sufficient for the specification and formation of the deuterosome inner core, Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CEP63 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MENQAHTTAGASPCEAELQELMEQIDIMVSNKKLDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLVMTQNYEGQLQTLKAQFSKLTSNFEKLRLHQMKQNQIHRKESSSKEELPFELSSLNQKLEEFRAKSREWDKQEVLYQTHLVSLDAQQKLLSEKCSQFQKQAQNYQTQLNGKKQCAEDSSSEIPRLVCESDPGCEATQRDEFIIEKLKSAVSEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKSELQSRDDLLRIIEMERLHLHRELLRMGEVQTAQDNRKRVESSYSPSPKEAERKRKELFPMVSDQPNHEKELSKMRSQLYQEEGLCSEQERLRSEISELTQELHQKEVTIATVMKKAALLERQLKIELEIKERMLAKQQVSDRRYKAVRTENTHLKGMMGDLDPARYLAVDLSNKKHSQCTSINKLEYENERLRSDLAKLHGNGKAAWPNQSSYGEAGAYVFQSQLKTETSGDRISQDCELNRSPTPLSPLPFQTKEMASPLVGDNEVLALSPPDISFRASLAAQHFLMEEERRAKELEKLLNTHIDELQRHTEFTLNKYTKLKQSRHI", "length": 601, "molWeight": 69678, "crc64": "66D8F0BC32D07A39", "md5": "BA6E1F4226110DE0B5F033691BD04D80"}}
{"primaryAccession": "Q7T3L1", "text": "This is Kininogen-1a protein, from Giant fire-bellied toad, contains 294 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7T3L1", "organism_name": "Giant fire-bellied toad", "protein_name": "Kininogen-1a", "length": 294, "firstPublicDate": "2005-01-04", "FUNCTION": "Plays a role in the control of feeding by the brain; intracerebroventricular administration of the peptide induced significant decrease in food intake in rats, Inhibits the bradykinin-induced in vitro relaxation of rat arterial smooth muscle, May target bradykinin receptors (BDKRB)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the bradykinin-related peptide family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRLWFCLSFFIVLCLEHFTGTLADERNVPESEEKTEQFLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDMYEIKQYKTAHGRPPICAPGEQCPIWVGK", "length": 294, "molWeight": 33857, "crc64": "7C87B4D88482C530", "md5": "86F6364114C29783F46D2F6A759B6773"}}
{"primaryAccession": "Q7TMA4", "text": "This is Free fatty acid receptor 4 protein, from Mouse, contains 361 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7TMA4", "organism_name": "Mouse", "protein_name": "Free fatty acid receptor 4", "length": 361, "firstPublicDate": "2005-05-10", "FUNCTION": "G-protein-coupled receptor for long-chain fatty acids (LCFAs) with a major role in adipogenesis, energy metabolism and inflammation, Signals via G-protein and beta-arrestin pathways (PubMed:27852822, PubMed:26873857), LCFAs sensing initiates activation of phosphoinositidase C-linked G proteins GNAQ and GNA11 (G(q)/G(11)), inducing a variety of cellular responses via second messenger pathways such as intracellular calcium mobilization, modulation of cyclic adenosine monophosphate (cAMP) production, and mitogen-activated protein kinases (MAPKs) (PubMed:27852822, PubMed:26873857), After LCFAs binding, associates with beta-arrestin ARRB2 that acts as an adapter protein coupling the receptor to specific downstream signaling pathways, as well as mediating receptor endocytosis (PubMed:27852822, PubMed:26873857), In response to dietary fats, plays an important role in the regulation of adipocyte proliferation and differentiation (PubMed:17250804, PubMed:22343897, PubMed:27853148, PubMed:29343498, PubMed:31761534), Acts as a receptor for omega-3 polyunsaturated fatty acids (PUFAs) at primary cilium of perivascular preadipocytes, initiating an adipogenic program via cAMP and CTCF-dependent chromatin remodeling that ultimately results in transcriptional activation of adipogenic genes and cell cycle entry (PubMed:31761534), Induces differentiation of brown and beige adipocytes probably via autocrine and endocrine functions of FGF21 hormone (PubMed:27853148, PubMed:29343498), Contributes to the thermogenic activation of brown adipose tissue and the browning of white adipose tissue (PubMed:27853148, PubMed:29343498), Activates brown adipocytes by initiating intracellular calcium signaling leading to mitochondrial depolarization and fission, and overall increased mitochondrial respiration (PubMed:29343498), Consequently stimulates fatty acid uptake and oxidation in mitochondria together with UCP1-mediated thermogenic respiration, eventually reducing fat mass (PubMed:29343498), Regulates bi-potential differentiation of bone marrow mesenchymal stem cells toward osteoblasts or adipocytes likely by up-regulating distinct integrins (PubMed:26365922), In response to dietary fats regulates hormone secretion and appetite (PubMed:15619630, PubMed:25535828, PubMed:24742677, PubMed:24663807, PubMed:24222669), Stimulates GIP and GLP1 secretion from enteroendocrine cells as well as GCG secretion in pancreatic alpha cells, thereby playing a role in the regulation of blood glucose levels (PubMed:15619630, PubMed:25535828, PubMed:24742677), Negatively regulates glucose-induced SST secretion in pancreatic delta cells (PubMed:24663807), Mediates LCFAs inhibition of GHRL secretion, an appetite-controlling hormone (PubMed:24222669), In taste buds, contributes to sensing of dietary fatty acids by the gustatory system (PubMed:20573884), During the inflammatory response, promotes anti-inflammatory M2 macrophage differentiation in adipose tissue (PubMed:20813258), Mediates the anti-inflammatory effects of omega-3 PUFAs via inhibition of NLRP3 inflammasome activation (By similarity), In this pathway, interacts with adapter protein ARRB2 and inhibits the priming step triggered by Toll-like receptors (TLRs) at the level of TAK1 and TAB1 (PubMed:20813258), Further inhibits the activation step when ARRB2 directly associates with NLRP3, leading to inhibition of pro-inflammatory cytokine release (By similarity), Mediates LCFAs anti-apoptotic effects (PubMed:15774482)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSPECAQTTGPGPSHTLDQVNRTHFPFFSDVKGDHRLVLSVVETTVLGLIFVVSLLGNVCALVLVARRRRRGATASLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTMSGSVTILTLAAVSLERMVCIVRLRRGLSGPGRRTQAALLAFIWGYSALAALPLCILFRVVPQRLPGGDQEIPICTLDWPNRIGEISWDVFFVTLNFLVPGLVIVISYSKILQITKASRKRLTLSLAYSESHQIRVSQQDYRLFRTLFLLMVSFFIMWSPIIITILLILIQNFRQDLVIWPSLFFWVVAFTFANSALNPILYNMSLFRNEWRKIFCCFFFPEKGAIFTDTSVRRNDLSVISS", "length": 361, "molWeight": 40813, "crc64": "D3A3F0BEB55F7B7B", "md5": "D781F40A9F1693023A300CA89D4D460A"}}
{"primaryAccession": "Q7TN78", "text": "This is Acyl-coenzyme A synthetase ACSM4, mitochondrial protein, from Rat, contains 580 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7TN78", "organism_name": "Rat", "protein_name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "length": 580, "firstPublicDate": "2007-10-02", "FUNCTION": "Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (PubMed:12709059), Capable of activating medium-chain fatty acids with a preference for C6-12 fatty acids (PubMed:12709059)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the ATP-dependent AMP-binding enzyme family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKVLLRCQRLRFIWLAKPAGRHFHRDPQLWAPLTLDDFEAINRCEKPLPKNFNFAADVLDQWSLKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQLTRKDILYRLQASKAKCIVASEEVAPAVDSIASECPNLKTKLLVSPHRWDGWLSFQELLQSASEEHNCVQTGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFSTWLRGACVFVHRMAQFNTDTFLDTLTSYPITTLCSAPTVYRMLVQQDLKRYQFKRLRHCLTGGEPLNPEVLEQWKAQTGLELYEGYGQTEVGIICANRKGEEIKPGSMGKGVVPYDVQIIDEHGNILPSGKEGEIALRLGSDRPFCFFSEYVDNPEKTDATIRRNFYITGDRGVMDDDGYLWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPFKSSNREKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWGRA", "length": 580, "molWeight": 65317, "crc64": "D9556CB46AAAB7C0", "md5": "FD2E553E51033E7145231D895106D3C8"}}
{"primaryAccession": "Q7X8R0", "text": "This is Transcription factor EAT1 protein, from Rice, contains 464 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7X8R0", "organism_name": "Rice", "protein_name": "Transcription factor EAT1", "length": 464, "firstPublicDate": "2016-06-08", "FUNCTION": "Transcription factor involved in the regulation of tapetum programmed cell death (PCD) and degradation during male reproductive development (PubMed:23519457, PubMed:23385589), Interacts with TDR and promote tapetal PCD by regulating the expression of RTS, and the two lipid-transfer proteins C4 and C6, which function in microspore development (PubMed:23519457), Acts downstream from and interacts with TDR in the regulation of tapetal PCD, Regulates directly the aspartic protease AP25 and AP37 during tapetal PCD (PubMed:23385589), May not target the cysteine protease CP1 (PubMed:23519457, PubMed:23385589)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bHLH protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIVGAGYFEDSHDQSLMAGSLIHDSNQAPASSENTSIDLQKFKVHPYSTEALSNTANLAEAARAINHLQHQLEIDLEQEVPPVETANWDPAICTIPDHIINHQFSEDPQNILVEQQIQQYDSALYPNGVYTPAPDLLNLMQCTMAPAFPATTSVFGDTTLNGTNYLDLNGELTGVAAVPDSGSGLMFASDSALQLGYHGTQSHLIKDICHSLPQNYGLFPSEDERDVIIGVGSGDLFQEIDDRQFDSVLECRRGKGEFGKGKGKANFATERERREQLNVKFRTLRMLFPNPTKNDRASIVGDAIEYIDELNRTVKELKILVEQKRHGNNRRKVLKLDQEAAADGESSSMRPVRDDQDNQLHGAIRSSWVQRRSKECHVDVRIVDDEVNIKLTEKKKANSLLHAAKVLDEFQLELIHVVGGIIGDHHIFMFNTKVSEGSAVYACAVAKKLLQAVDVQHQALDIFN", "length": 464, "molWeight": 51522, "crc64": "7C657E0A53A431C3", "md5": "91E02F5633156D74C79200A9D303FF33"}}
{"primaryAccession": "Q7Y1W1", "text": "This is Protein TIC 56, chloroplastic protein, from Mouse-ear cress, contains 527 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7Y1W1", "organism_name": "Mouse-ear cress", "protein_name": "Protein TIC 56, chloroplastic", "length": 527, "firstPublicDate": "2015-01-07", "FUNCTION": "Involved in protein precursor import into chloroplasts, May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSMNFNPFQNWFEKPPNPVPSINFVSLADSFFPKSQSPNFASIGLPKFSKKSPKPETAGTDEPGPYKQIAEQFLWECENIPDYRHTPEVDKLLNEDPVFEKKENPSTEEIEAEQKWWESFRASPVVQFMTRAEEIADDMNKMELEDNDTPYRKEDKDYWRAIPHVPGFDGRPMPRKAIKSKEESDDKFWDFMKQFLFGLWGFRQRPYPPGRPIDVAQAIGYKRLEKRYYDFIMKTGGWWYKDRLGRSRGPCEIITLKTAYGAGIIDRDTFIWGEDMDEWAPIHMVYGLEPAIATWEVRLGAAATAFLHKLQKGIPPWVPLKGREPKTYKQLQKEAIESKKRDMAVLEANGGVWPGVRTPSHALFLWASGSELTTVLESDHMPNKFIPKQLRLELAKVIPGLRPWEVISIEQAMDQISYGGEWYREPLGTYTTGPPYIREWNRSVMRLFRIFYNLSVRVGQKLERTVPGFDTIMDKVQKDYDKRIARRMKRREEELREEDLKHYSGRTDEDEEEEEEEDDDSNSKKD", "length": 527, "molWeight": 61625, "crc64": "2288A8B688D0E79E", "md5": "771278A003E2C547496591C7A5EF8BC1"}}
{"primaryAccession": "Q7Z7L1", "text": "This is Schlafen family member 11 protein, from Human, contains 901 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7Z7L1", "organism_name": "Human", "protein_name": "Schlafen family member 11", "length": 901, "firstPublicDate": "2007-04-03", "FUNCTION": "Inhibitor of DNA replication that promotes cell death in response to DNA damage (PubMed:22927417, PubMed:26658330, PubMed:29395061), Acts as a guardian of the genome by killing cells with defective replication (PubMed:29395061), Persistently blocks stressed replication forks by opening chromatin across replication initiation sites at stressed replication forks, possibly leading to unwind DNA ahead of the MCM helicase and block fork progression, ultimately leading to cell death (PubMed:29395061), Acts independently of ATR (PubMed:29395061), Also acts as an interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis (PubMed:23000900), Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner (PubMed:23000900), Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides (PubMed:23000900), The exact inhibition mechanism is unclear: may either sequester tRNAs, prevent their maturation via post-transcriptional processing or may accelerate their deacylation (PubMed:23000900), Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA (PubMed:23000900)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Schlafen family, Subgroup III subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEANQCPLVVEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGVIRMAKKVEHPVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPRLCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPKILEEGPFHKIHKGVYQELPNSDPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFANTGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIVNVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQLSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLWRDLISEHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKTFLRENFEHIQHIVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCSGLPPLSDQYPREELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGVQGTLRIKKYLTVEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKKRVVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHLYIFPWGGH", "length": 901, "molWeight": 102836, "crc64": "514FD89CB7C12E8D", "md5": "328E9AAA3597D216388EF087DEBE796C"}}
{"primaryAccession": "Q7ZVT3", "text": "This is Spindle assembly abnormal protein 6 homolog protein, from Zebrafish, contains 627 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7ZVT3", "organism_name": "Zebrafish", "protein_name": "Spindle assembly abnormal protein 6 homolog", "length": 627, "firstPublicDate": "2005-04-12", "FUNCTION": "Central scaffolding component of the centrioles ensuring their 9-fold symmetry (PubMed:21273447), Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTELLFNKRLQVLVKSKDTDERRSVIRVSIELQLPSSPVHRKDLVVRLTDDTDLYFLYNLIISEEDFQSLKVQQGLLIDFTSFPQKFIDLLEQCICEQDKESPRFLLQLSSSSSAFDHSPSNLNIVETNAFKHLTHLSLKLLPGSDTDIKKYLASCLSSVKEEKQQLQQKLRKTEEDLTRQLNYAQQTLSEKSRELDKLRSEWTSQTTSLSSRHMQDLTAEREKALETQSRLQQQNEQLRQELESSHHRSTQQLQTKVSELETANRELIDKKYKSDSTIRDLKAKLTSLEEECQRSKQQVLSLRRENSALDSECHEKERLLNQLQTRVAVLEQEIKDKDQLVLRTKEVLEATQQQKNSVEGNAESKQLQISKLESTVKSLSEELIKANGIIKKLQADLKALLGKIKVKNSVTVPQEKILQETSDKLQRQQRELQDTQQRLSLKEEEAAKLKEQLEATVQKLDESREVLKTNENVITWLNKQLNENQLSRKQETVAMFETPAAALRSAAVPHNMAFPITSTINSKYPLALSCVSSGSRSVLTSSNGPKVQFNPMSVKPSAAEVSPAAFSQPANKENSEPVGLDSKYFERRDDSIPLRGLLPSMHLNREVPKPLNTAAAKATPSAFFPG", "length": 627, "molWeight": 71315, "crc64": "068636706A28E4E7", "md5": "B19585CA8DC7BDC225BDFB3454358139"}}
{"primaryAccession": "Q804Q5", "text": "This is Fez family zinc finger protein 2 protein, from Zebrafish, contains 430 amino acids, has 6 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [249, 271], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [277, 299], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [305, 327], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [333, 355], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [361, 383], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [389, 412], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q804Q5", "organism_name": "Zebrafish", "protein_name": "Fez family zinc finger protein 2", "length": 430, "firstPublicDate": "2007-07-10", "FUNCTION": "Transcription repressor, Component of the regulatory cascade that controls the development of dopaminergic (DA) and serotonergic (5HT) neurons", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 6}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASSLPLETVMSCPRLDDRSGATAAPKSLAFSIDRIMSKTSEPKAAAAEERSEGKKTVGLCSPIPCMIPIQPFSYDLQAKALMNYSEFWKVNFRGALCTSAAMCKTNCGVCSKADAGIKHSVLPGTRVIKPQVIHQALAMPANGSLCYFNYLDSAYQSELLSGHLFSSAIANSQAQAISAHQKLLLLENAKLACVSPEKFPTPQYPHKEHLPGQLDQIVRESHNLTEKNGVKAHSKTNNCSSDGKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCSICSKAFHQIYNLTFHMHTHNDKKPFTCGTCGKGFCRNFDLKKHIRKLHDNANCLSGGNDSSRGHQN", "length": 430, "molWeight": 47541, "crc64": "BF144ECE87F38F0E", "md5": "BC77EDE4A1CC8A741C29BA769C077018"}}
{"primaryAccession": "Q80US8", "text": "This is Max dimerization protein 3 protein, from Mouse, contains 206 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q80US8", "organism_name": "Mouse", "protein_name": "Max dimerization protein 3", "length": 206, "firstPublicDate": "2006-10-17", "FUNCTION": "Transcriptional repressor, Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3', Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEPVASNIQVLLQAAEFLERREREAEHGYASLCPHHSPGTVCRRRKPPLQAPGALNSGRSVHNELEKRRRAQLKRCLEQLRQQMPLGVDCTRYTTLSLLRRARVHIQKLEEQEQQARRLKEKLRSKQQSLQQQLEQLQGLPGARERERLRADSLDSSGLSSERSDSDQEDLEVDVESLVFGTETELLQSFSAGREHSYSHSTCAWL", "length": 206, "molWeight": 23635, "crc64": "17E1149064907085", "md5": "C22DA0F00ABB34778DCE2195DA79E39E"}}
{"primaryAccession": "Q80WW9", "text": "This is DDRGK domain-containing protein 1 protein, from Mouse, contains 315 amino acids, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q80WW9", "organism_name": "Mouse", "protein_name": "DDRGK domain-containing protein 1", "length": 315, "firstPublicDate": "2003-09-26", "FUNCTION": "Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, which plays a key role in reticulophagy (also called ER-phagy) (By similarity), In response to endoplasmic reticulum stress, promotes recruitment of the E3 UFM1-protein ligase UFL1 to the endoplasmic reticulum membrane: in turn, UFL1 mediates ufmylation of proteins such as RPN1 and RPL26/uL24, promoting reticulophagy of endoplasmic reticulum sheets (By similarity), Ufmylation-dependent reticulophagy inhibits the unfolded protein response (UPR) by regulating ERN1/IRE1-alpha stability (PubMed:28128204), Ufmylation in response to endoplasmic reticulum stress is essential for processes such as hematopoiesis or inflammatory response (PubMed:30701081), Required for TRIP4 ufmylation, thereby regulating nuclear receptors-mediated transcription (PubMed:28263186), May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B (PubMed:28263186), Plays a role in cartilage development through SOX9, inhibiting the ubiquitin-mediated proteasomal degradation of this transcriptional regulator (PubMed:28263186)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DDRGK1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVGPWVYLVAAVLLIGLILFLTRSRGRAAAADGEPLHNEEERAGAGQVGRSLPQESEEQRTGSRPRRRRDLGSRLQAQRRAQRVAWEDGDENVGQTVIPAQEEEGIEKPAEVHPTGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLKEEQKEEEERKAQEEQARREHEEYLKLKEAFVVEEEGVSETMTEEQSHSFLTEFINYIKKSKVVLLEDLAFQMGLRTQDAINRIQDLLTEGTLTGVIDDRGKFIYITPEELAAVANFIRQRGRVSITELAQASNSLISWGQDLPAQASA", "length": 315, "molWeight": 35977, "crc64": "D973B9AFBE265562", "md5": "0128D369D33601FB60E7E2E02C4C3D92"}}
{"primaryAccession": "Q80Z64", "text": "This is Homeobox protein NANOG protein, from Mouse, contains 305 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q80Z64", "organism_name": "Mouse", "protein_name": "Homeobox protein NANOG", "length": 305, "firstPublicDate": "2006-11-28", "FUNCTION": "Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal (PubMed:25825768), Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes, Acts as a transcriptional activator or repressor, Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3', Binds to the POU5F1/OCT4 promoter (By similarity), Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression, When overexpressed, promotes cells to enter into S phase and proliferation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Nanog homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVGLPGPHSLPSSEEASNSGNASSMPAVFHPENYSCLQGSATEMLCTEAASPRPSSEDLPLQGSPDSSTSPKQKLSSPEADKGPEEEENKVLARKQKMRTVFSQAQLCALKDRFQKQKYLSLQQMQELSSILNLSYKQVKTWFQNQRMKCKRWQKNQWLKTSNGLIQKGSAPVEYPSIHCSYPQGYLVNASGSLSMWGSQTWTNPTWSSQTWTNPTWNNQTWTNPTWSSQAWTAQSWNGQPWNAAPLHNFGEDFLQPYVQLQQNFSASDLEVNLEATRESHAHFSTPQALELFLNYSVTPPGEI", "length": 305, "molWeight": 34240, "crc64": "4EF96408B767C79F", "md5": "1A63D76C8117F2E16744CE9B0ED4AF86"}}
{"primaryAccession": "Q84JH7", "text": "This is Sirohydrochlorin ferrochelatase, chloroplastic protein, from Mouse-ear cress, contains 225 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84JH7", "organism_name": "Mouse-ear cress", "protein_name": "Sirohydrochlorin ferrochelatase, chloroplastic", "length": 225, "firstPublicDate": "2016-02-17", "FUNCTION": "Chelates iron to the siroheme precursor, Catalyzes the last step of the siroheme biosynthesis, Unlike its counterparts in bacteria, contains an [Fe-S] cluster which is not involved directly in the enzymatic reaction, but may play regulatory role in iron, sulfur and tetrapyrrole metabolism (PubMed:15545265, PubMed:22414210), The [Fe-S] cluster is required for normal plant growth (PubMed:22414210)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the CbiX family, SirB subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTTQSQFLVNLSYGGLASQSNLRANNRVSPSSCQITRTNRSWALPVSFKVEKFQLQRGRRRRGSPCFGESEGLVKNGIGDADGIIIVDHGSRRRESNLMLEEFVKMFKEKTGYPIVEPAHMELAEPSIKDAFSLCVQQGAKRVVVSPFFLFPGRHWHTDIPSLTADAAKEFSGISYLITAPLGPHNLLLDVVNDRIQHCLSHVEGDADECLVCAGTNKCKLYNSS", "length": 225, "molWeight": 24925, "crc64": "B0B64F1303184827", "md5": "E303049189D16C22A4233345E93A2A9F"}}
{"primaryAccession": "Q84K00", "text": "This is NAC domain-containing protein 78 protein, from Mouse-ear cress, contains 567 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84K00", "organism_name": "Mouse-ear cress", "protein_name": "NAC domain-containing protein 78", "length": 567, "firstPublicDate": "2004-08-16", "FUNCTION": "Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity), Transcripition activator associated with the induction of genes related to flavonoid biosynthesis and required for the accumulation of anthocyanins in response to high light stress (PubMed:19887540), Plays a role in the regulation of 20S and 26S proteasomes in response to high light stress (PubMed:21889048)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGRGSVTSLAPGFRFHPTDEELVRYYLKRKVCNKPFKFDAISVTDIYKSEPWDLPDKSKLKSRDLEWYFFSMLDKKYSNGSKTNRATEKGYWKTTGKDREIRNGSRVVGMKKTLVYHKGRAPRGERTNWVMHEYRLSDEDLKKAGVPQEAYVLCRIFQKSGTGPKNGEQYGAPYLEEEWEEDGMTYVPAQDAFSEGLALNDDVYVDIDDIDEKPENLVVYDAVPILPNYCHGESSNNVESGNYSDSGNYIQPGNNVVDSGGYFEQPIETFEEDRKPIIREGSIQPCSLFPEEQIGCGVQDENVVNLESSNNNVFVADTCYSDIPIDHNYLPDEPFMDPNNNLPLNDGLYLETNDLSCAQQDDFNFEDYLSFFDDEGLTFDDSLLMGPEDFLPNQEALDQKPAPKELEKEVAGGKEAVEEKESGEGSSSKQDTDFKDFDSAPKYPFLKKTSHMLGAIPTPSSFASQFQTKDAMRLHAAQSSGSVHVTAGMMRISNMTLAADSGMGWSYDKNGNLNVVLSFGVVQQDDAMTASGSKTGITATRAMLVFMCLWVLLLSVSFKIVTMVSAR", "length": 567, "molWeight": 63511, "crc64": "05EB16AB22AEDFDE", "md5": "1DEE9093168F7A851A96515D42D7F872"}}
{"primaryAccession": "Q84LH8", "text": "This is Transcription factor PIF5 protein, from Mouse-ear cress, contains 444 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84LH8", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor PIF5", "length": 444, "firstPublicDate": "2008-04-08", "FUNCTION": "Transcription factor acting negatively in the phytochrome B signaling pathway to promote the shade-avoidance response, Regulates PHYB abundance at the post-transcriptional level, possibly via the ubiquitin-proteasome pathway, Promotes ethylene activity in the dark, May regulate the expression of a subset of genes by binding to the G-box motif, Might be involved in the integration of light-signals to control both circadian and photomorphogenic processes, Activated by CRY1 and CRY2 in response to low blue light (LBL) by direct binding at chromatin on E-box variant 5'-CA[CT]GTG-3' to stimulate specific gene expression to adapt global physiology (e,g, hypocotyl elongation in low blue light) (PubMed:26724867)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEQVFADWNFEDNFHMSTNKRSIRPEDELVELLWRDGQVVLQSQARREPSVQVQTHKQETLRKPNNIFLDNQETVQKPNYAALDDQETVSWIQYPPDDVIDPFESEFSSHFFSSIDHLGGPEKPRTIEETVKHEAQAMAPPKFRSSVITVGPSHCGSNQSTNIHQATTLPVSMSDRSKNVEERLDTSSGGSSGCSYGRNNKETVSGTSVTIDRKRKHVMDADQESVSQSDIGLTSTDDQTMGNKSSQRSGSTRRSRAAEVHNLSERRRRDRINERMKALQELIPHCSRTDKASILDEAIDYLKSLQMQLQVMWMGSGMAAAAAAAASPMMFPGVQSSPYINQMAMQSQMQLSQFPVMNRSAPQNHPGLVCQNPVQLQLQAQNQILSEQLARYMGGIPQMPPAGNQMQTVQQQPADMLGFGSPAGPQSQLSAPATTDSLHMGKIG", "length": 444, "molWeight": 49302, "crc64": "593D72C1F2ED86C7", "md5": "3D31B647C0849616E136482CE0458FDF"}}
{"primaryAccession": "Q84LM2", "text": "This is Vacuolar-processing enzyme beta-isozyme 1 protein, from Rice, contains 497 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84LM2", "organism_name": "Rice", "protein_name": "Vacuolar-processing enzyme beta-isozyme 1", "length": 497, "firstPublicDate": "2015-03-04", "FUNCTION": "Asparagine-specific endopeptidase that may be involved in processing of proteins targeted to vacuoles, Cysteine protease required for post-translational proteolysis of seed storage proteins in the protein storage vacuole (PSV) of developing seeds, by processing of proglutelin precursor to mature glutelin subunits, thus contributing to the formation of protein crystalline structures in PSV (Ref,1, PubMed:19154227, PubMed:19933265)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the peptidase C13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAARCWVWGFVVALLAVAAAADGEEEEGKWEPLIRMPTEEGDDAEAAAPAPAPAAADYGGTRWAVLVAGSSGYGNYRHQADVCHAYQILQKGGVKEENIVVFMYDDIAHNILNPRPGTIINHPKGGDVYAGVPKDYTGHQVTTENFFAVLLGNKTAVTGGSGKVIDSKPEDHIFIYYSDHGGPGVLGMPNLPYLYAGDFIKVLQKKHASNSYSKMVIYVEACESGSIFEGLMPENLNIYVTTASNAVENSWGTYCPGEEPSPPPEYITCLGDMYSVAWMEDSETHNLKKETIEDQYELVKKRTSNANKLNEGSHVMEYGDKTFKDEKLFLYQGFNPANGNITNELIWPVPKATVNQRDADLLFMWKRYEQLNGVSEDKLRALREIEDTIAHRKHLDSSIDFIGKLVFGFENGPLALEAARSSGQPLVDNWDCLKKMVRIFESQCGSLTQYGMKYMRAFANICNNGVSEAKMMEASINACGRYNSARWSPMTEGGHSA", "length": 497, "molWeight": 54886, "crc64": "763ADC8F30380A6D", "md5": "377342F728AC23C4DA231FA1B260C0EB"}}
{"primaryAccession": "Q84TH4", "text": "This is Serine/arginine-rich splicing factor SR45a protein, from Mouse-ear cress, contains 382 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84TH4", "organism_name": "Mouse-ear cress", "protein_name": "Serine/arginine-rich splicing factor SR45a", "length": 382, "firstPublicDate": "2014-07-09", "FUNCTION": "Probable splicing factor involved in constitutive and/or alternative splicing events, May bridge the 5' and 3' components of the spliceosome", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the splicing factor SR family, SR45 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGKREIHFTPVGRQVQRVLEYPLRLENRSPMSYSRRSRYSPSLSPYDKRRGRSVSRSLSRSPTRSVSSDAENPGNSLYVTGLSHRVTERDLEDHFAKEGKVTDVHLVLDPWTRESRGFGFISMKSVGDANRCIRSLDHSVLQGRVITVEKARRRRGRTPTPGKYLGLRTARGRHKSPSYSPRRSVSCSRSRSRSYSSDRGRSYSPSYGRRGRSSSYSPFYRRRRFYSPSRSPSPDDRYNRRRDRSYSPYYRRRDRSRSYSRNCRARDRSPYYMRRYRSRSRSYSPRYRARDRSCSPYYRGRDRSYSPHYQGRDRSYSPESRYYRRHRSVSGSVSPGGRSMSRSISPRKGRKESRSKSRRHDRQSSMCHSRSARSSTSRSVSP", "length": 382, "molWeight": 44978, "crc64": "FFD7E9C734D89D19", "md5": "8024250956C9D4EE24504AD9A4B28976"}}
{"primaryAccession": "Q84VQ4", "text": "This is NAD(P)H-quinone oxidoreductase subunit U, chloroplastic protein, from Mouse-ear cress, contains 218 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84VQ4", "organism_name": "Mouse-ear cress", "protein_name": "NAD(P)H-quinone oxidoreductase subunit U, chloroplastic", "length": 218, "firstPublicDate": "2015-02-04", "FUNCTION": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain, The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone, Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASLSTITQPSLVHIPGESVLHHVPSTCSFPWKPTINTKRIICSPARNSSEVSAEAETEGGSSTAVDEAPKESPSLISALNVERALRGLPITDVDHYGRLGIFRNCSYDQVTIGYKERVKELKEQGLDEEQLKTKMDLIKESYTILSTVEERRMYDWSLARSEKAERYVWPFEVDIMEPSREEPPPQEPEDVGPTRILGYFIGAWLVLGVALSVAFNR", "length": 218, "molWeight": 24438, "crc64": "FA29630525BC222B", "md5": "0EB94C5C926D380888B7970AD582DCE8"}}
{"primaryAccession": "Q86B79", "text": "This is RING finger protein unkempt protein, from Fruit fly, contains 599 amino acids, has 5 C3H1-type Zinc finger, has 1 RING-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [71, 100], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [111, 141], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [194, 220], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [230, 264], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [272, 300], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [556, 591], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q86B79", "organism_name": "Fruit fly", "protein_name": "RING finger protein unkempt", "length": 599, "firstPublicDate": "2003-08-29", "FUNCTION": "Essential for late larval/early pupal development", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the unkempt family", "domain_description": {"C3H1-type Zinc finger": 5, "RING-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLANETNKLLLSSQQEKPNHYTYLKEFRVEQCQSFLQHKCNQHRPFVCFNWHFQNQRRRRPVRKRDGTFNYSADNYCTKYDETTGICPEGDECPYLHRTAGDTERRYHLRYYKTCMCVHDTDSRGYCVKNGLHCAFAHGMQDQRPPVYDIKELETLQNAESTLDSTNALNALDKERNLMNEDPKWQDTNYVLANYKTEPCKRPPRLCRQGYACPQYHNSKDKRRSPRKYKYRSTPCPNVKHGEEWGEPGNCEAGDNCQYCHTRTEQQFHPEIYKSTKCNDVQQAGYCPRSVFCAFAHVEPCSMDDPRENSLSASLANTSLLTRSSAPINIPNTTLSNSINDFNSGSFAVNIPSSSLTYSPTNHANLFNVDAFNYGGSNKLSNSLSATQNDSSLFFPSRIISPGFGDGLSISPSVRISELNTIRDDINSSSVGNSLFENTLNTAKNAFSLQSLQSQNNSDLGRITNELLTKNAQIHKLNGRFEDMACKLKIAELHRDKAKQEAQEWKERYDLAQIQLNLPAELRDLSIQKLKQLQSKLRTDLEEVDKVLYLENAKKCMKCEENNRTVTLEPCNHLSICNTCAESVTECPYCQVPVITTHT", "length": 599, "molWeight": 68442, "crc64": "4BCBD702FF6C9846", "md5": "FC5D40F110287451441AA9BC96714D20"}}
{"primaryAccession": "Q86DA5", "text": "This is NAD(+) hydrolase tir-1 protein, from Caenorhabditis elegans, contains 981 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86DA5", "organism_name": "Caenorhabditis elegans", "protein_name": "NAD(+) hydrolase tir-1", "length": 981, "firstPublicDate": "2005-05-10", "FUNCTION": "Regulates expression of antimicrobial peptide nlp-29 in response to fungal infection or physical injury", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the SARM1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLPNRKPPRPSPSFQSLNNNNQRFPLRRSLKIAQAHSLPTVPSEDAKDDDLITPELSTDFDFREIQHRYLMALQNEQDGETTSTDDAFFELDDDDDLSSPSVPGSPVDPPSISVPLPPKSAPPCPTQPAPLTNGDLYPTILSNGTPIPNGRITPALSTVSVSLIHEARLQQSLSTPCNGSEEEMHNGQVRKESEYRRFKSEGSTAGASLPAAEKTHMDELSPVDQRSTSGTARFLIQQDSVVNPSTKMSNTEQVAMMHTLKTKLSKYQAMMDKAFEEIAKVEDANIIEGCTIVRKLMRKVWNTPKVSADLANALCDYLRDRDYFDKLIKMFISPNTAACDQVRMECGKVLEECTSSANLEYIVNKSYTKKIMIVAMKLNKTPDQQRLSLSLIGNLFKHSNAVSLSLIETDVIDHIILTFKRAPECPDILRHAALALANILLYTCFEGKKKIIQKKIPEWLFFLASQADDVTRYYACIAVCTIVSVKEFEPLVRKSDTMKLVEPFLQVHDPATFARDYHKYAQGNTKEWLERLLPMLQPSRRREARSVAAFHFTLEATIKKEQNKLDVFQEIGAIQALKEVASSPDEVAAKFASEALTVIGEEVPYKLAQQVPGWTCADVQYWVKKIGFEEYVEKFAKQMVDGDLLLQLTENDLKHDVGMISGLHRKRFLRELQTLKVAADYSSVDESNLDNFLMGLSPELSVYTYQMLTNGVNRSLLSSLTDEMMQNACGITNPIHRLKLTQAFETAKHPDDVEVAMLSKQIDVFISYRRSTGNQLASLIKVLLQLRGYRVFIDVDKLYAGKFDSSLLKNIQAAKHFILVLTPNSLDRLLNDDNCEDWVHKELKCAFEHQKNIIPIFDTAFEFPTKEDQIPNDIRMITKYNGVKWVHDYQDACMAKVVRFITGELNRTTPTTKEMPSISRKTTQQRWQTTNTVSRTGPSRSIGGPRMEPPTPTFTPTGSQERATSTRRKIQPSASTTSDRN", "length": 981, "molWeight": 110556, "crc64": "B114E320A3FF6CCA", "md5": "FCD090C2BDB8C69C601330DC63DDFE89"}}
{"primaryAccession": "Q86IV5", "text": "This is Countin-1 protein, from Social amoeba, contains 258 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86IV5", "organism_name": "Social amoeba", "protein_name": "Countin-1", "length": 258, "firstPublicDate": "2008-04-08", "FUNCTION": "Cell-counting factor that limits the maximum size of the multicellular structure, May down-regulate the expression of gp24, which mediates cell adhesion", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the countin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNKLFSLILALFLVNSAVVSSLDSCSICVDFVGNSLNDLLNIILNSGVIGTCGDLCSAVPGGQIVDTVCDLLCDYVGVDEFIKLISDVDPDPIYICEKISVCKTNDNAAASLDLVQINPQNGTVGGTFTLSIAYTVTNTIATGQLAFNIIDPTGNAFGDAVLLVQQSPEQYTQQFQFQATPSEQESFPNGLYTVQALVCEGSCGSPHPNTYTLANGTTTFTISGADSSSMSGAGSFSGSSQSTQTGAASGSGSGFALF", "length": 258, "molWeight": 26659, "crc64": "725F37870E78356A", "md5": "7B2676407A82DA7054C5C75CCDD84F6D"}}
{"primaryAccession": "Q86JM7", "text": "This is P2X receptor A protein, from Social amoeba, contains 378 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86JM7", "organism_name": "Social amoeba", "protein_name": "P2X receptor A", "length": 378, "firstPublicDate": "2009-12-15", "FUNCTION": "P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling, Not required for the purinergic response to extracellular nucleotides, Inward currents evoked by intracellular ATP and ATP analogs, Exclusively selective for ATP over other nucleotides, Insensitive to P2 receptor antagonists PPADS, suramin and 2',3'-O-(2,4,6-trinitrophenyl)-ATP but inhibited by nanomolar concentrations of copper and sodium ion, More permeable to ammonium than either sodium or potassium ions and less permeable to choline, It has been reported that p2xA is not essential for osmoregulation (PubMed:19833731), however this information is in contradiction with another source (PubMed:17625565) which indicates that p2xA is required for osmoregulation, Found to be permeable to chloride ions, Inhibited by copper and sodium ions", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the P2X receptor family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGFSFDWDDIFQYSTVKIVRIRDRRLGILHLSFLVGIVAYIVVYSAIIKKGYLFTEVPIGSVRTSLKGPNTFASNLTYCSNQQHNGSTYPFTPLECNYWDEQLALFPVGQDSTFTCTTRVRLSKQEANCNFTDPTCKFVDEPGSAKNIYIADIESFTILIDHTMYASSSGSQFNAVDLHGYILNQDGDEVQIDANGTSIGVSGKPDIMTIGQLLSFGGVSLDQASPVDSNVSIRYDGVVLFVFITYSNTYTYSTSDFKYVYSVQQIANTIYDVPETIILESIHSRLLYKRHGIRVIFIQTGTIGSFHFQTLLLTLVSGLGLLAVATTVVDQLAIRLLPQRKSYSSLKFQVTESMSNPMKKRITTDEGEDVLYTRIEGL", "length": 378, "molWeight": 42186, "crc64": "1DCBD07B25093094", "md5": "4B6A3961B383AE61655119438CCB1F76"}}
{"primaryAccession": "Q86LE5", "text": "This is Antimicrobial peptide microplusin protein, from Cattle tick, contains 110 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86LE5", "organism_name": "Cattle tick", "protein_name": "Antimicrobial peptide microplusin", "length": 110, "firstPublicDate": "2010-03-23", "FUNCTION": "Has bacteriostatic activity against the Gram-positive bacterium M,luteus, but not against Gram-negative bacterium E,coli SBS363, Has fungistatic activity against C,neoformans, but not C,albicans, Binds and sequesters copper and iron ions, Copper-chelating is crucial for antimicrobial activity against M,luteus", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKAIFVSALLVVALVASTSAHHQELCTKGDDALVTELECIRLRISPETNAAFDNAVQQLNCLNRACAYRKMCATNNLEQAMSVYFTNEQIKEIHDAATACDPEAHHEHDH", "length": 110, "molWeight": 12182, "crc64": "42B815904D9B0D98", "md5": "42CCC532A3B46DADFAB3A918E6D45828"}}
{"primaryAccession": "Q86T26", "text": "This is Transmembrane protease serine 11B protein, from Human, contains 416 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86T26", "organism_name": "Human", "protein_name": "Transmembrane protease serine 11B", "length": 416, "firstPublicDate": "2007-09-11", "FUNCTION": "Serine protease", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MYRHGISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVEKTYYYQGDFHISGVTYNDNCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKFKFPPAEGVSMRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTGL", "length": 416, "molWeight": 46337, "crc64": "0A9C369EA6F348A3", "md5": "A876380D958FD4CDBF93BB4B458F18D9"}}
{"primaryAccession": "Q86UN3", "text": "This is Reticulon-4 receptor-like 2 protein, from Human, contains 420 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86UN3", "organism_name": "Human", "protein_name": "Reticulon-4 receptor-like 2", "length": 420, "firstPublicDate": "2006-02-07", "FUNCTION": "Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity), Plays a functionally redundant role in postnatal brain development, Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum, Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system, Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (By similarity), Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed:22325200), Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed:22325200)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Nogo receptor family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLPGLRRLLQAPASACLLLMLLALPLAAPSCPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLIRTLRPGTFGSNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAWFQRARVSSSDVTCATPPERQGRDLRALREADFQACPPAAPTRPGSRARGNSSSNHLYGVAEAGAPPADPSTLYRDLPAEDSRGRQGGDAPTEDDYWGGYGGEDQRGEQMCPGAACQAPPDSRGPALSAGLPSPLLCLLLLVPHHL", "length": 420, "molWeight": 46106, "crc64": "09B9E875BC88A0E8", "md5": "2EE418F9C1032C16DDBA897487390D15"}}
{"primaryAccession": "Q86VD7", "text": "This is Mitochondrial coenzyme A transporter SLC25A42 protein, from Human, contains 318 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86VD7", "organism_name": "Human", "protein_name": "Mitochondrial coenzyme A transporter SLC25A42", "length": 318, "firstPublicDate": "2007-06-26", "FUNCTION": "Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGNGVKEGPVRLHEDAEAVLSSSVSSKRDHRQVLSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQILLRHLQS", "length": 318, "molWeight": 35409, "crc64": "D42F26C200D3EACF", "md5": "E1978D92609CC8BDEBCFE5086B1F60EA"}}
{"primaryAccession": "Q86VD9", "text": "This is GPI mannosyltransferase 4 protein, from Human, contains 579 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86VD9", "organism_name": "Human", "protein_name": "GPI mannosyltransferase 4", "length": 579, "firstPublicDate": "2006-07-25", "FUNCTION": "Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis, Transfers a fourth mannose to some trimannosyl-GPIs during GPI precursor assembly, The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyltransferase 22 family, PIGZ subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQICGSSVASVAAGTSFQVLGPVCWQQLDLKMAVRVLWGGLSLLRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVLFPLLISGSTFWLLRLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPMGADRWNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSWLLGGIVAAGFFNRPTFLAFAVVPLYLWGTRGATNPGLKSLTREALVLLPGAALTAAVFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVLLCSPQTQPVPWKGTVVLFNALGALLFGCLHQGGLVPGLEYLEQVVHAPVLPSTPTHYTLLFTHTYMPPRHLLHLPGLGAPVEVVDMGGTEDWALCQTLKSFTRQPACQVAGGPWLCRLFVVTPGTTRRAVEKCSFPFKNETLLFPHLTLEDPPALSSLLSGAWRDHLSLHIVELGEET", "length": 579, "molWeight": 63471, "crc64": "684FD8293BD09909", "md5": "F21353E6BCAC2E2ED9F295F0C2073813"}}
{"primaryAccession": "Q86VW1", "text": "This is Solute carrier family 22 member 16 protein, from Human, contains 577 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86VW1", "organism_name": "Human", "protein_name": "Solute carrier family 22 member 16", "length": 577, "firstPublicDate": "2008-02-26", "FUNCTION": "High affinity carnitine transporter; the uptake is partially sodium-ion dependent, Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa, Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin, The uptake of TEA is inhibited by various organic cations, The uptake of doxorubicin is sodium-independent", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGSRHFEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWSLEDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESENESKSSKLLLTTNNSGLEKTEAITPRDSGLGE", "length": 577, "molWeight": 64614, "crc64": "EA4ABBED0AE99632", "md5": "9444ABE62F2B20E3F3316989DB967BA2"}}
{"primaryAccession": "Q86WV5", "text": "This is CST complex subunit TEN1 protein, from Human, contains 123 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86WV5", "organism_name": "Human", "protein_name": "CST complex subunit TEN1", "length": 123, "firstPublicDate": "2008-05-20", "FUNCTION": "Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex, The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves, Initially the CST complex has been proposed to protect telomeres from DNA degradation (PubMed:19854130), However, the CST complex has been shown to be involved in several aspects of telomere replication, The CST complex inhibits telomerase and is involved in telomere length homeostasis; it is proposed to bind to newly telomerase-synthesized 3' overhangs and to terminate telomerase action implicating the association with the ACD:POT1 complex thus interfering with its telomerase stimulation activity, The CST complex is also proposed to be involved in fill-in synthesis of the telomeric C-strand probably implicating recruitment and activation of DNA polymerase alpha (PubMed:22763445), The CST complex facilitates recovery from many forms of exogenous DNA damage; seems to be involved in the re-initiation of DNA replication at repaired forks and/or dormant origins (PubMed:25483097)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TEN1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMLPKPGTYYLPWEVSAGQVPDGSTLRTFGRLCLYDMIQSRVTLMAQHGSDQHQVLVCTKLVEPFHAQVGSLYIVLGELQHQQDRGSVVKARVLTCVEGMNLPLLEQAIREQRLYKQERGGSQ", "length": 123, "molWeight": 13856, "crc64": "C713E9B40C2A5E34", "md5": "4D116F386B5233C03B687623751C0458"}}
{"primaryAccession": "Q86Y34", "text": "This is Adhesion G protein-coupled receptor G3 protein, from Human, contains 549 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86Y34", "organism_name": "Human", "protein_name": "Adhesion G protein-coupled receptor G3", "length": 549, "firstPublicDate": "2004-07-19", "FUNCTION": "Orphan receptor that regulates migration of lymphatic endothelial cells in vitro via the small GTPases RhoA and CDC42 (PubMed:24178298), Regulates B-cell development (By similarity), Seems to signal through G-alpha(q)-proteins (PubMed:22575658)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATPRGLGALLLLLLLPTSGQEKPTEGPRNTCLGSNNMYDIFNLNDKALCFTKCRQSGSDSCNVENLQRYWLNYEAHLMKEGLTQKVNTPFLKALVQNLSTNTAEDFYFSLEPSQVPRQVMKDEDKPPDRVRLPKSLFRSLPGNRSVVRLAVTILDIGPGTLFKGPRLGLGDGSGVLNNRLVGLSVGQMHVTKLAEPLEIVFSHQRPPPNMTLTCVFWDVTKGTTGDWSSEGCSTEVRPEGTVCCCDHLTFFALLLRPTLDQSTVHILTRISQAGCGVSMIFLAFTIILYAFLRLSRERFKSEDAPKIHVALGGSLFLLNLAFLVNVGSGSKGSDAACWARGAVFHYFLLCAFTWMGLEAFHLYLLAVRVFNTYFGHYFLKLSLVGWGLPALMVIGTGSANSYGLYTIRDRENRTSLELCWFREGTTMYALYITVHGYFLITFLFGMVVLALVVWKIFTLSRATAVKERGKNRKKVLTLLGLSSLVGVTWGLAIFTPLGLSTVYIFALFNSLQGVFICCWFTILYLPSQSTTVSSSTARLDQAHSASQE", "length": 549, "molWeight": 60861, "crc64": "C9AB0D95B2F26DDA", "md5": "30E6EA5BCB8E769B6CF4050281FF597C"}}
{"primaryAccession": "Q86YI8", "text": "This is PHD finger protein 13 protein, from Human, contains 300 amino acids, has 1 PHD-type Zinc finger, is soluble, locates in Nucleus.", "functionDomainRange": [{"location": [232, 280], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "Q86YI8", "organism_name": "Human", "protein_name": "PHD finger protein 13", "length": 300, "firstPublicDate": "2003-08-15", "FUNCTION": "Modulates chromatin structure, Required for normal chromosome condensation during the early stages of mitosis, Required for normal chromosome separation during mitosis", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDSDSCAAAFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDAGFSDIASSVPLPVSDRCFSHLQPTLLQRAKPSNFLLDRKKTDKLKKKKKRKRRDSDAPGKEGYRGGLLKLEAADPYVETPTSPTLQDIPQAPSDPCSGWDSDTPSSGSCATVSPDQVKEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRTGSRKLFLD", "length": 300, "molWeight": 33582, "crc64": "197663A113B995F2", "md5": "7B69F5EECC791A72F4864DA7D0057BF1"}}
{"primaryAccession": "Q86Z20", "text": "This is Coiled-coil domain-containing protein 125 protein, from Human, contains 511 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86Z20", "organism_name": "Human", "protein_name": "Coiled-coil domain-containing protein 125", "length": 511, "firstPublicDate": "2007-05-29", "FUNCTION": "May be involved in the regulation of cell migration", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSKVARSSSESDVQLWETEEDDMTEGDLGYGLGRKPGGIYEIEFSHRSRKRSDGKNFSPPPFPRKGEERNEASFQYSKHKSQQDTFPQVSRISNYRRQSSTVDSNSELSNEELRQCLNETLEEVEMLKTELEASQRQLRGKEEALKILQSMAILGKATSHTQAVLQKTMEQNRSLEKEINALQWEIEFDHNRFKNIEESWIQKYDRLNCENAVLKENLKVKTEEIKMLKSDNAVLNQRYLEALAMLDIKQQKMAQENMCCDKSGFAEASGLELAVLGACLCHGPGGNPCSCARMAASTRKLLLQLKQELEILQKSKEEAYVMADAFRIAFEQQLMRKNDQALQLTQMDKMHKKATKWMNWKHLKEDGFPSPRSKKTFGQRLLGMLPSENSSKRMEDQDSPQEVLKMLIDLLNDKEEALAHQRKVSYMLARALEDKDTASNENKEKNPIKENFPFNNPWRKTSEFSVLGDPIHSSVCILNSVGCICSIQHSQIDPNYRTLKRSHSLPSSIIF", "length": 511, "molWeight": 58629, "crc64": "B6174A2DDA1CE2DA", "md5": "5AC800FED27C8D35F280ABCDF473349D"}}
{"primaryAccession": "Q8BG60", "text": "This is Thioredoxin-interacting protein protein, from Mouse, contains 397 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BG60", "organism_name": "Mouse", "protein_name": "Thioredoxin-interacting protein", "length": 397, "firstPublicDate": "2006-10-03", "FUNCTION": "May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability, Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm, Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) (By similarity), Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest, Required for the maturation of natural killer cells, Acts as a suppressor of tumor cell growth", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the arrestin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGSQQCKQTLDYLRYEDTLLLEEQPTAGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRPSQPTQEAKKNFEVMDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKGFCEGDDISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVFTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILKVEYSLLIYVSVPGSKKVILDLPLVIGSRSGLSSRTSSMASRTSSEMSWIDLNIPDTPEAPPCYMDIIPEDHRLESPTTPLLDDVDDSQDSPIFMYAPEFQFMPPPTYTEVDPCVLNNNNNNNNVQ", "length": 397, "molWeight": 44363, "crc64": "C160781B207C99A6", "md5": "08FC28C336339944B5B0191EC39792FD"}}
{"primaryAccession": "Q8BGV8", "text": "This is Mitochondrial dynamics protein MID51 protein, from Mouse, contains 463 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BGV8", "organism_name": "Mouse", "protein_name": "Mitochondrial dynamics protein MID51", "length": 463, "firstPublicDate": "2007-11-13", "FUNCTION": "Mitochondrial outer membrane protein which regulates mitochondrial fission, Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins, Regulates DNM1L GTPase activity and DNM1L oligomerization, Binds ADP and can also bind GDP, although with lower affinity, Does not bind CDP, UDP, ATP, AMP or GTP, Inhibits DNM1L GTPase activity in the absence of bound ADP, Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP, Does not require ADP for its function in recruiting DNM1L", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MID49/MID51 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSPTRLSHSGKRSWEEPNWMGSPRLLNKDMKAGLSRSLQTLPTDSSAFDTDTFCPPRPKPLARRGQVDLKKSRLRMSLQEKLLSYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEVQYEKDKHLVIDFLPSVTLGDTVLVARPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPQEIDELGYTLYCSLSEPEVLLQT", "length": 463, "molWeight": 51184, "crc64": "69C8869807974024", "md5": "EB77CD0BD7DEF373AF88C2CBBA4A0FE3"}}
{"primaryAccession": "Q8BHP7", "text": "This is Olfactomedin-like protein 2A protein, from Mouse, contains 681 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BHP7", "organism_name": "Mouse", "protein_name": "Olfactomedin-like protein 2A", "length": 681, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEAAAVLPRYLQLRLLLVLLLLVLLRAGPVWPDSKVFSDLDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETVSSGADCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKLQSMVDLLEGALYSMDLMKVHAYIQKVASQMNTLEESIKANLSLENKVVKDSVHHLSEQLKSYENQSAIMMSIKKELSSLGLQLLQRDAAAVPATAPASSPDSKAQDTAGGQGRDLNKYGSIQKSFSDKGLAKPPKEKLLKVEKLRKESIKGRIPQPTARPRALAQQQAVIRGFTYYKAGRQEARQEARQEAPKAAADSTLKGTSWLEKLPPKIEAKLPEPNSAKHDDVRLQASEGGNLTPDITTTTTSTSSSTTTTTGTTSTTSTTSTTSTTTPSPITTPWPTEPPLHPEVPSQGREDSCEGTLRAVDPPVKHHSYGRHEGAWMKDPAALDDRIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAVDEHDETQHEVIVLSRLDPADLSVHRETTWKTRLRRNSYGNCFLVCGILYTVDTYNQHEGQVAYAFDTHTGTDAHPQLPFLNEYSYTTQVDYNPKERVLYAWDNGHQLTYTLHFVV", "length": 681, "molWeight": 76547, "crc64": "89B22A48BECC66BD", "md5": "2948A536C84B910EF3DFD4361EC32998"}}
{"primaryAccession": "Q8BL65", "text": "This is Actin-binding LIM protein 2 protein, from Mouse, contains 612 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BL65", "organism_name": "Mouse", "protein_name": "Actin-binding LIM protein 2", "length": 612, "firstPublicDate": "2004-12-07", "FUNCTION": "May act as scaffold protein, May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSAVSQPQAAHAPLEKPASTAILCNTCGNVCKGEVLRVQNKYFHIRCFVCKACGCDLAEGGFFVRQGEHICTRDYQRLYGTRCFSCDRFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSPPTLLGNSAHVAQGLRSCGGCGLEIKNGQALVALDKHWHLGCFKCKTCGKLLNAEYISKDGLPYCEADYHSKFGIRCDGCEKYITGRVLEAGEKHYHPSCALCVRCGQMFSEGEEMYLQGSSIWHPACRQAARTEDKSKETRTSSESIVSVPASSTSGSPSRVIYAKLGDEILDYRDLAALPKNKAIYNIDRPDMISYSPYISHSAVGDRQSYGEGDQDDRSYKQCRTSSPSSAGSVSLGHYTPTSRSPQHYSRPGSESGRSTPSLSVHSDSRPPSSTYQQAPRHFHVPDTGVKDNIYRKPPIYKQHAARRLDVEDSSFDQDSRKKTTWLLLKGDADTRTNSPDLDSQSLSLSSGTDQEPLQRMAGDSLYSRFPYSKPDTLPGPRKDGLDLRNANLAPCGADPDASWGTREYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF", "length": 612, "molWeight": 68107, "crc64": "97FE5A9C049AD455", "md5": "BEAC0A99403FC061E3FB1B8314DE0EB3"}}
{"primaryAccession": "Q8BSF4", "text": "This is Phosphatidylserine decarboxylase proenzyme, mitochondrial protein, from Mouse, contains 406 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BSF4", "organism_name": "Mouse", "protein_name": "Phosphatidylserine decarboxylase proenzyme, mitochondrial", "length": 406, "firstPublicDate": "2003-05-30", "FUNCTION": "Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer), Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine, May be involved in lipid droplet biogenesis at the endoplasmic reticulum membrane (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the phosphatidylserine decarboxylase family, PSD-B subfamily, Eukaryotic type I sub-subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAASGGRACVRSLRGGVLWRSSPCHYESTATRHFLGTLQKLPLQAGVRNFHTAPVRSLFLLRPVPILLATGGGYAGYRQYEKYRERKLEKLGLEIPPKLASHWEVSLYKSVPTRLLSRACGRLNQVELPYWLRRPVYSLYIWTFGVNMTEAAVEDLHHYRNLSEFFRRKLKPQARPVCGLHCVTSPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGPRANTEDLPFPPASSSDSFRNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDRDLHTNSPRYSKGSYNDLSFVTHANKEGIPMRKGEPLGEFNLGSTIVLIFEAPKDFNFRLKAGQKIRFGEALGSL", "length": 406, "molWeight": 45927, "crc64": "6614312FA8BA9704", "md5": "F7A13CA918524B3F0BC847109C59ECA7"}}
{"primaryAccession": "Q8BZQ2", "text": "This is Cysteine-rich secretory protein LCCL domain-containing 2 protein, from Mouse, contains 495 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BZQ2", "organism_name": "Mouse", "protein_name": "Cysteine-rich secretory protein LCCL domain-containing 2", "length": 495, "firstPublicDate": "2009-02-10", "FUNCTION": "Promotes matrix assembly", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSCLLNNMVLMGLALLVCGVQAFFLPNTTSLEKLLSKYQHAEPHSRVRRAIPMSDRQEILMLHNKLRGQVYPPASNMEHMTWDEELERSAAAWAHRCLWEHGPAGLLRSIGQNLAVHWGRYRSPGFHVQSWYDEVKDYTYPYPHECTPRCRERCSGPMCTHYTQMVWATTNKIGCAVHTCRNMNVWGDTWENAVYLVCNYSPKGNWIGEAPYKHGRPCSECPSSYGGGCLNNLCHRAEKPHKHKPEVDMMNEVESPPAPEETHVWVQPRVIKTKKTPVINFMTQVVHCDTKMKDSCKGSTCNRYQCPAGCLSNKAKVFGSLFYESSSSICRAAIHYGVIDDRGGLVDVTRNGMVPFFVKSQKNGMESLSKYKPSSSFTVSKVTETAVDCHATVAQLCPFEKPATHCPRIQCPARCGEEPSYWAPVYGTNIYADTSSICKAAVHAGVIVDEVGGYADVMPVDKKKSYVGSLRNGVQSESLNTPQNGNAFRIFAVRQ", "length": 495, "molWeight": 55432, "crc64": "7F6D25DDC489610C", "md5": "C600B24C1DB80F4D261389B201994491"}}
{"primaryAccession": "Q8C0D7", "text": "This is Inhibitor of growth protein 4 protein, from Mouse, contains 249 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [196, 245], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8C0D7", "organism_name": "Mouse", "protein_name": "Inhibitor of growth protein 4", "length": 249, "firstPublicDate": "2005-01-04", "FUNCTION": "Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4, Through chromatin acetylation it may function in DNA replication, May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation, Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA, May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC, Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1) (By similarity), Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (PubMed:11888890)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ING family", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLRQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKAAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK", "length": 249, "molWeight": 28528, "crc64": "6C5C5582A249E412", "md5": "3287AFDCD635C7F34A29383DF0B9D4DA"}}
{"primaryAccession": "Q8C0V1", "text": "This is Telomere repeats-binding bouquet formation protein 1 protein, from Mouse, contains 768 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8C0V1", "organism_name": "Mouse", "protein_name": "Telomere repeats-binding bouquet formation protein 1", "length": 768, "firstPublicDate": "2008-02-26", "FUNCTION": "Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis (PubMed:24885367, PubMed:24413433, PubMed:26548954), Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex, During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA (PubMed:26548954), In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment' (PubMed:26548954), Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex (PubMed:24885367, PubMed:24413433), Also recruits cohesin to telomeres to develop structural rigidity (PubMed:24413433)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TERB1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MESEKPKKTQEMKTDLKLLLECLKYHMGNPLSQKEVLITIHSVCKQNSDAGIYFREIGGLMFIINLAKSSEQSLVKEAALYTLGSIAEENVYCQQSLCTSELFQDLTGLLTNDDSNTNLKRMSVYVLLVLVSNNRNGQTLVREVGCIEVLSQMFRTVLSNYELNLSDNSVFQSYLLWSSVCSTLCVCVNNPQNDENQMLCCSLFPCVNEWLMNCMRPEVIRPICSFIGLTLANNTHAQNCFVSSGGLDVLCQVLVQLESDSHNTLSSAKLAVIVTKTMDACITDNSAAFTVVLSKYHIVSTLLALLLHESLDSREKFSIILAIGHCTEDCEKNQYELLKNNGLPLMIQALTEFKNEDLSKAATYVLHNCKKITGKLSLSLGQNSFGENEIELKDISEKETLREHWKAAKEILCRIKQFEKGGKEEKQQNRSGHYKDNTPSMKVNIQTNLKRLCADSTGGTRAEDKDINQSRELRSYKPSEIMSKACANENQLTTRKKNTNPVHPFCKEKGQSKIVHETTPSCAQNLDKEKTFDQKDSVSQSSDQVLKHLPHTVKNRKQVPETDPFTLCLDIIDREVGIQATDSCSRMLKYTCSGCIVARKLLNSRNFSKFLHSCAYQCVHHKVIMEAEDKYKNELRKTFICAKKILLTPCRRRQLCKESTASEELKIVHQKPDSKKLPGLEAQALNTSIPEAMERRSPVPGQSGLHKKRRIRKDFTKEEVNYLFHGVKTMGNHWNSILWSFPFQKGRRAVDLAHKYHRLIKGPSCAAL", "length": 768, "molWeight": 86835, "crc64": "EEA1F16E6258BFA6", "md5": "3714DD3AB6300457691BCC88B5F84BCE"}}
{"primaryAccession": "Q8C1E7", "text": "This is Ion channel TACAN protein, from Mouse, contains 343 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8C1E7", "organism_name": "Mouse", "protein_name": "Ion channel TACAN", "length": 343, "firstPublicDate": "2007-11-13", "FUNCTION": "Ion channel involved in sensing mechanical pain (PubMed:32084332), Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli (PubMed:32084332), May also be required for efficient adipogenesis (PubMed:26024229)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TMEM120 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQSPPPDPLGDCLRNWEDLQQDFQGIQETHRLYRLKLEELTKLQANCTNSITRQKKRLQELALVLKKCRPSLPSESMEAAQELENQMKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILIVISFTCRFLLNSRVTDAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLFNALTLFNLARDPECKEWQVLMCGFPFLLLFLGNFFTTLRVVHQKFHSQQHGNKKD", "length": 343, "molWeight": 40751, "crc64": "7AC1BE2A31E0A6C1", "md5": "682D7ECF711ED29C08B246325EA557B6"}}
{"primaryAccession": "Q8C1Q4", "text": "This is Meteorin protein, from Mouse, contains 291 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8C1Q4", "organism_name": "Mouse", "protein_name": "Meteorin", "length": 291, "firstPublicDate": "2004-07-19", "FUNCTION": "Involved in both glial cell differentiation and axonal network formation during neurogenesis, Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia, Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the meteorin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLVATLLCALCCGLLAASAHAGYSEDRCSWRGSGLTQEPGSVGQLTLDCTEGAIEWLYPAGALRLTLGGPDPGTRPSIVCLRPERPFAGAQVFAERMTGNLELLLAEGPDLAGGRCMRWGPRERRALFLQATPHRDISRRVAAFRFELHEDQRAEMSPQAQGLGVDGACRPCSDAELLLAACTSDFVIHGTIHGVAHDTELQESVITVVVARVIRQTLPLFKEGSSEGQGRASIRTLLRCGVRPGPGSFLFMGWSRFGEAWLGCAPRFQEFSRVYSAALTTHLNPCEMALD", "length": 291, "molWeight": 31469, "crc64": "643B933B7D127973", "md5": "D94D232922414097227D54FF49E56BD2"}}
{"primaryAccession": "Q8CCK0", "text": "This is Core histone macro-H2A.2 protein, from Mouse, contains 372 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8CCK0", "organism_name": "Mouse", "protein_name": "Core histone macro-H2A.2", "length": 372, "firstPublicDate": "2006-03-21", "FUNCTION": "Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, May be involved in stable X chromosome inactivation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEILELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGTKGKSETILSPPPEKRGRKAASGKKGGKKSKATKPRTSKKSKAKDSDKEGTSNSTSEDGPGDGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEEIGKALEKAGGKEFLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSSSSLKNVYFLLFDSESIGIYVQEMAKLDTK", "length": 372, "molWeight": 40092, "crc64": "471E3CDCE28F4A1D", "md5": "A53CCD7591BC050ABBDB82B902331E21"}}
{"primaryAccession": "Q8CD91", "text": "This is SPARC-related modular calcium-binding protein 2 protein, from Mouse, contains 447 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8CD91", "organism_name": "Mouse", "protein_name": "SPARC-related modular calcium-binding protein 2", "length": 447, "firstPublicDate": "2003-10-31", "FUNCTION": "Can stimulate endothelial cell proliferation, migration, as well as angiogenesis (By similarity), Promotes matrix assembly and cell adhesiveness", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLPPQLCWLPLLAALLPPVPAQKFSALTFLRVDQDKDRDCSLDCPSSPQKPLCASDGRTFLSRCEFQRAKCKDPQLEIAHRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRCPGSINEKVPQREGAGKADDAAAPALETQPQGDEEDIASRYPTLWTEQVKSRQNKTNKNSASSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKNRPLQGCPGAKKHEFLTSVLDALSTDMVHAVSDPSSSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDMNNDKSITVQELMGCLGVTREEGKANTRKRHTPRGNAESSSSNRQPRKQG", "length": 447, "molWeight": 49891, "crc64": "26AB802F9D13A00C", "md5": "1F24D59271EF39A262D70CD2A4E2C3E9"}}
{"primaryAccession": "Q8CFH6", "text": "This is Serine/threonine-protein kinase SIK2 protein, from Mouse, contains 931 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8CFH6", "organism_name": "Mouse", "protein_name": "Serine/threonine-protein kinase SIK2", "length": 931, "firstPublicDate": "2005-02-15", "FUNCTION": "Serine/threonine-protein kinase that plays a role in many biological processes such as fatty acid oxidation, autophagy, immune response or glucose metabolism (PubMed:12624099, PubMed:16817901, PubMed:29211348), Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction (PubMed:12624099), Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators (PubMed:16817901), Phosphorylates EP300 and thus inhibits its histone acetyltransferase activity, In turn, regulates the DNA-binding ability of several transcription factors such as PPARA or MLXIPL (By similarity), Also plays a role in thymic T-cell development (PubMed:34732767)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLSIAQIKEHKWMLIEVPVQRPILYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKTVESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTIAEQTVAKAQTVGLPVTLHPPNVRLMRSTLLPQASNVEAFSFPTSSCQAEAAFMEEECVDTPKVNGCLLDPVPPVLVRKGCQSLPSSMMETSIDEGLETEGEAEEDPSQAFEAFQATRSGQRRHTLSEVTNQLVVMPGAGKMFSMSDNPSLESVDSEYDMGSAQRDLNFLEDSPSLKDIMLANQPSPRMTSPFISLRPANPAMQALSSQKREAHNRSPVSFREGRRASDTSLTQGIVAFRQHLQNLARTKGILELNKVQLLYEQMGSNADPTLTSTAPQLQDLSSSCPQEEISQQQESVSSLSASMHPQLSPQQSLETQYLQHRLQKPNLLPKAQSPCPVYCKEPPRSLEQQLQEHRLQQKRLFLQKQSQLQAYFNQMQIAESSYPGPSQQLALPHQETPLTSQQPPSFSLTQALSPVLEPSSEQMQFSSFLSQYPEMQLQPLPSTPGPRAPPPLPSQLQQHQQPPPPPPPPPPQQPGAAPTSLQFSYQTCELPSTTSSVPNYPASCHYPVDGAQQSNLTGADCPRSSGLQDTASSYDPLALSELPGLFDCEMVEAVDPQHNGVVSCLARET", "length": 931, "molWeight": 104198, "crc64": "5CF2FB8DCDC689F4", "md5": "10C70FDD6CA86F23269206EDB38F505B"}}
{"primaryAccession": "Q8CFP6", "text": "This is DnaJ homolog subfamily C member 27 protein, from Mouse, contains 273 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8CFP6", "organism_name": "Mouse", "protein_name": "DnaJ homolog subfamily C member 27", "length": 273, "firstPublicDate": "2008-05-20", "FUNCTION": "GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed, May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the small GTPase superfamily, Rab family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "METNVPKRKEPAKSLRIKVISMGNAEVGKSCIIKRYCEKRFVSKYLATIGIDYGVTKVQVRDREIKVNIFDMAGHPFFFEVRNEFYKDTQGVILVYDVGQKDSFDALDSWLAEMKQELGPHGNMDNIVFVVCANKIDCSKHRCIDESEGRLWAESKGFLYFETSAQTGEGINEMFQTFYLSIVDLCENGGKRPTASSSASFTKEQADTIRRIRNSKDSWEMLGVRPGASREEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTALLKNIK", "length": 273, "molWeight": 30831, "crc64": "805523789CECC329", "md5": "53EC8371C69CC94951D34C45D6F5999D"}}
{"primaryAccession": "Q8CFZ5", "text": "This is Solute carrier family 22 member 12 protein, from Mouse, contains 553 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8CFZ5", "organism_name": "Mouse", "protein_name": "Solute carrier family 22 member 12", "length": 553, "firstPublicDate": "2007-10-23", "FUNCTION": "Electroneutral antiporter that translocates urate across the apical membrane of proximal tubular cells in exchange for monovalent organic or inorganic anions (PubMed:14747372), Involved in renal reabsorption of urate and helps maintaining blood levels of uric acid (PubMed:14747372), Mediates urate uptake by an exchange with organic anions such as (S)-lactate and nicotinate, and inorganic anion Cl(-) (PubMed:14747372), Other inorganic anions such as Br(-), I(-) and NO3(-) may also act as counteranions that exchange for urate (By similarity), Also mediates orotate tubular uptake coupled with nicotinate efflux and to a lesser extent with lactate efflux, therefore displaying a potential role in orotate renal reabsorption, Orotate transport is Cl(-)-dependent (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFPELLDRVGGLGRFQLFQTVALVTPILWVTTQNMLENFSAAVPHHRCWVPLLDNSTSQASIPGDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAATEPCEDGWVYDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTLNALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRRKAEGDTLTMEVLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISMLCWFAFGFTFYGLALDLQALGSNIFLLQALIGIVDFPVKTGSLLLISRLGRRFCQVSFLVLPGLCILSNILVPHGMGVLRSALAVLGLGCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVLSGLAALLLPETKNLPLPDTIQDIQKQSVKKVTHDTPDGSILMSTRL", "length": 553, "molWeight": 60194, "crc64": "D331583A8D54DBBF", "md5": "25A7E3B69B51016E88DA7F30F87F6FD3"}}
{"primaryAccession": "Q8CIG3", "text": "This is Lysine-specific histone demethylase 1B protein, from Mouse, contains 826 amino acids, has 1 CW-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [133, 193], "description": "CW-type", "keyword_description": "Zinc finger", "textural_description": "CW-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8CIG3", "organism_name": "Mouse", "protein_name": "Lysine-specific histone demethylase 1B", "length": 826, "firstPublicDate": "2006-07-25", "FUNCTION": "Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor, Required for de novo DNA methylation of a subset of imprinted genes during oogenesis, Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed, Demethylates both mono- and di-methylated 'Lys-4' of histone H3, Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4 (PubMed:19407342, PubMed:19727073), Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of GLYR1 to achieve such activity, they form a multifunctional enzyme complex that modifies transcribed chromatin and facilitates Pol II transcription through nucleosomes (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the flavin monoamine oxidase family", "domain_description": {"CW-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAASRGRSKKRSNLELSPDNLPLRSSGRQAKKKAVEIPDEDEDGSSEKKYRKCEKAGCTAAYPVCFASASERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYSAWKRVWTSNGKTEPSPKAFMADQQLPYWVQCTKPECGKWRQLTKEIQLTPHMARTYRCGMKPNTITKPDTPDHCSFPEDLRVLEVSNHWWYPMLIQPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTHRATVTAATTTTGSASPGEMEPSKAAPSSLVLGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLTVAAGQHLLPKHYHNKSVLVVGAGPAGLAAARQLHNFGMKVTVLEAKDRIGGRVWDDKSFKGVVVGRGPQIVNGCINNPVALMCEQLGISMRKLGERCDLIQEGGRITDPTVDKRMDFHFNALLDVVSEWRKDKTLLQDVPLGEKIEEIYRAFVKESGIQFSELEGQVLQFHLSNLEYACGSSLHQVSARSWDHNEFFAQFAGDHTLLTPGYSTIIEKLAEGLDIRLKSPVQSIDYTGDEVQVTTTDGMGHSAQKVLVTVPLAILQRGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASQRGLFAVFYDMDSQQSVLMSVITGEAVASLRTMDDKQVLQQCMGILRELFKEQEIPEPTKYFVTRWSTEPWIQMAYSFVKTFGSGEAYDIIAEEIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF", "length": 826, "molWeight": 92633, "crc64": "02FD6FE991B1C030", "md5": "9D23C5F065ED6AEFFAFEC5741B5C7AC9"}}
{"primaryAccession": "Q8CIV2", "text": "This is Membralin protein, from Mouse, contains 574 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8CIV2", "organism_name": "Mouse", "protein_name": "Membralin", "length": 574, "firstPublicDate": "2005-07-05", "FUNCTION": "May have a role in the ERAD pathway required for clearance of misfolded proteins in the endoplasmic reticulum (ER), Promotes survival of motor neurons, probably by protecting against ER stress", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the membralin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSEHAAAPGPGPNGGGGGGAAPVRGPRGPNLNPNPLINVRDRLFHALFFKMAVTYSRLFPPAFRRLFEFFVLLKALFVLFVLAYIHIVFSRSPINCLEHVRDRWPREGVLRVEVRHNSSRAPVILQFCDGGLGGLELEPGGLELEEEELTVEMFTNSSIKFELDIEPKVFKPQSGADALNDSQDFPFPETPAKVWPQDEYIVEYSLEYGFLRLSQATRQRLSIPVMVVTLDPTRDQCFGDRFSRLLLDEFLGYDDILMSSVKGLAENEENKGFLRNVVSGEHYRFVSMWMARTSYLAAFVIMVIFTLSVSMLLRYSHHQIFVFIVDLLQMLEMNMAIAFPAAPLLTVILALVGMEAIMSEFFNDTTTAFYIILTVWLADQYDAICCHTNTSKRHWLRFFYLYHFAFYAYHYRFNGQYSSLALVTSWLFIQHSMIYFFHHYELPAILQQIRIQEMLLQTPPLGPGTPTALPDDLNNNSGSPATPDPSPPLALGPSSSPAPTGGASGPGSLGAGASVSGSDLGWVAETAAIISDASFLSGLSASLLERRPTAPSTPDSSRPDPGVPLEDAPAPAGS", "length": 574, "molWeight": 63561, "crc64": "898C0EBDF9B25FD1", "md5": "AF8AA131DB488D8191C1DD30B83E0519"}}
{"primaryAccession": "Q8GUK1", "text": "This is Protein DGS1, mitochondrial protein, from Mouse-ear cress, contains 602 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GUK1", "organism_name": "Mouse-ear cress", "protein_name": "Protein DGS1, mitochondrial", "length": 602, "firstPublicDate": "2016-03-16", "FUNCTION": "Involved in galactoglycerolipid biosynthesis (PubMed:18208519), Contributes to an intracellular signal that regulates an alternative DGD1-independent galactoglycerolipid biosynthesis pathway in chloroplasts (PubMed:18208519, PubMed:20181751), Being involved in mitochondrial lipid homeostasis, modulates mitochondrion biogenesis and physiology, as well as stress responses (PubMed:31118221)", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDSQPPVNESTPSTALSNFGELVPFYSSYLWNRLASLLPTSKPIFLGKISNLYRQTVSRKRSISFPLPLPSDFPSSSTITSNVSADTARIHGVLEEIMADVLSNLHDIQKSLDFWRSRAEGSNARKAYFMIFERGPTAFVNESTKFVSKSLSEDSAMQHLCQSSSSHMTERMRVLVELRSALASFIAQLYVELDKRGEDLVKIPEKALPSLLAVINGLFSNLEGSFSHLHAVRECDSSVDGSYPMPLVFDRLPEVNEEGSQWTDCELTDAINLVHKNLEKLNSYLSVMVGKHRKPRRMTLYWVRYTCGAVGLSVFSIWLLRHSSLMGSSDIENWVHDAKEATMSFFSDHVEQPLLSIRDELFDTFRKRHKGVMETEEVQLTQDSLHRMLRNFCEQATREKVPDNASDQEMLEVVMNRYEKELVHPIHNLLSGELARGLLIQVQKLKLDIETAMLELDQILRANEINFAILAALPAFFLSIVMLTVLRTWLKKDSKAQGRGRIARIHRRLLVVEIEKRIMQYQSYIEQGRDKDAETVFGLLIYSLERLYRVVEKPARATDEWDLVKQDLIELGRPQQQTSYKLTVTQRLVTVYDCLLPTLKRQ", "length": 602, "molWeight": 68894, "crc64": "446D017974ADEAED", "md5": "0E34D677DA9DB4022C84F53A19604353"}}
{"primaryAccession": "Q8GUK7", "text": "This is E3 ubiquitin-protein ligase RMA3 protein, from Mouse-ear cress, contains 243 amino acids, has 1 RING-type Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [44, 92], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8GUK7", "organism_name": "Mouse-ear cress", "protein_name": "E3 ubiquitin-protein ligase RMA3", "length": 243, "firstPublicDate": "2010-07-13", "FUNCTION": "E3 ubiquitin-protein ligase", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEGNFFIRSDAQRAHDNGFIAKQKPNLTTAPTAGQANESGCFDCNICLDTAHDPVVTLCGHLFCWPCIYKWLHVQLSSVSVDQHQNNCPVCKSNITITSLVPLYGRGMSSPSSTFGSKKQDALSTDIPRRPAPSALRNPITSASSLNPSLQHQTLSPSFHNHQYSPRGFTTTESTDLANAVMMSFLYPVIGMFGDLVYTRIFGTFTNTIAQPYQSQRMMQREKSLNRVSIFFLCCIILCLLLF", "length": 243, "molWeight": 26984, "crc64": "707894C1C74D167B", "md5": "3933CA92402C1A8DEC9DFCC839A13D1C"}}
{"primaryAccession": "Q8GWE6", "text": "This is Enhanced ethylene response protein 5 protein, from Mouse-ear cress, contains 413 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GWE6", "organism_name": "Mouse-ear cress", "protein_name": "Enhanced ethylene response protein 5", "length": 413, "firstPublicDate": "2016-01-20", "FUNCTION": "Involved in the regulation of ethylene response (PubMed:18429939), Probable TREX-2 component required for nuclear RNA export, The TREX-2 complex (transcription and export complex 2) functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket), TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (PubMed:19843313)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAYVSMGEAHRRITEYLNRFCDAVSYQDSSTLCRLLSFSSNSPPLLSLADALNVFQDSSSLIRQSDRFSEYGEILAHVFRSLQSYRVGNLVEAYLAFDKFANAFVQEFRNWESAWALEALYVVCYEIRVLAEKADKDLTSNGKSPEKLKAAGSLLMKVFGVLAGKGPKRVGALYVTCQLFKTYFKLGTVNLCRSVIRSIETARIFDFEEFPRRDKVTYMYYTGRLEVFNENFPAADTKLSYALQNCNPKRERNIRMILKYLVPVKLSLGIIPKDELLRNYNLHEYTKIVQALRKGDLRLLRHALQEHEDRFLRSGVYLVLEKLELQVYQRLMKKIYINQKLSDPARAHQLKLEGIAKALRWLDMDMDLDEVECIMTILIYKNLVKGYLAHKSKVVVLSKQDPFPKLNGKPVSS", "length": 413, "molWeight": 47614, "crc64": "9D60990CAF1C3A76", "md5": "E0721977FE490D16355E7C9FE40294A3"}}
{"primaryAccession": "Q8GXA4", "text": "This is WPP domain-interacting protein 1 protein, from Mouse-ear cress, contains 489 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GXA4", "organism_name": "Mouse-ear cress", "protein_name": "WPP domain-interacting protein 1", "length": 489, "firstPublicDate": "2008-09-02", "FUNCTION": "Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips (PubMed:17600715, PubMed:18591351), As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDLESESSALESVDDNVLIQQSASNVCDDGRSLDNGSCSDESVKLLSTSNSVELGKPMSFDSPGDGGGAYSPVLKGQGLRKWRRIRRDLVKDTSANMENSKALKRGLSGVAHSHGKQMQFQSPEVEQESQGSVGSVNMLKSSGDGFDILGSSGYDSRFVAGVGFSAGMDLEIDDDRSSKSSTVARAPKVIRYEKPMISSGQGGNIRVENSKKHRGESVDFEKENSYSSLESDSRKQSGRMMDYNGENGETSMRKDDAGGEGGESINTDNRYSDEMDPLTEAINGFLALQDALEKEVQQFQEIGNEPMPQHHEQVSEANSPHPEIVTLVNNVEQLENMLEETRSMLEVKESHIRDLESTTNQSKHSWGGTEIVVEDIFRQKIEAEIEYLIYSRSIDNLNSQMKLIDEQESLAEEQTHETLNKLGRVQTKAANFTNRAQDLQNDCIEITGTIKKRACKITSYVLIQLVLLSTVVLLLLSQLLPEPDTVVPT", "length": 489, "molWeight": 53902, "crc64": "3DCD663768750292", "md5": "B277D44306151C1E3FD197059B76C14F"}}
{"primaryAccession": "Q8GXN9", "text": "This is G patch domain-containing protein TGH protein, from Mouse-ear cress, contains 930 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GXN9", "organism_name": "Mouse-ear cress", "protein_name": "G patch domain-containing protein TGH", "length": 930, "firstPublicDate": "2015-01-07", "FUNCTION": "Functions as component of microRNA (miRNA) and small interfering RNA (siRNA) biogenesis, May assist DCL1 and DCL4 to efficiently process and/or recruit the precursors of miRNAs and siRNAs, In the miRNA biogenesis pathway, associates with the DCL1 complex that processes primary miRNAs (pri-miRNAs) into miRNAs, Binds pri-miRNAs and precursor miRNAs (pre-miRNAs), Is required for the interaction between pri-miRNAs and DRB1 (PubMed:22802657), Required for general proper plant growth and, in particular, initiation of vascular development, Interacts genetically with AMP1, a glutamate carboxypeptidase involved in the regulation of meristem function (PubMed:16024589)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGSDEEDFVFHGTPIEREEEIASRKKKAVAGASGNLRTLPAWKQEVTDEEGRRRFHGAFTGGYSAGYYNTVGSKEGWAPQSFTSSRQNRAGARKQSISDFLDEDEKADMEGKSLSASSQFDTFGFTAAEHSRKHAEKEQHERPSAIPGPVPDELVAPVSESIGVKLLLKMGWRRGHSIKEVRASSDARREARKAFLAFYTDENTKETPDSLVSETEVETSLGEDIKISESTPVYVLNPKQDLHGLGYDPFKHAPEFREKKRSRMSANKEVGFRKPLSMKESLFGPKSGKIAPGFGIGALEELDVEDEDVYAGYDFDQTYVIEDEQPARQSNDNRLRLTSKEHDVLPGFGAAKNSDYSMERFNPPIIPKDFVARHKFSGPLEAETKPTVSAPPEVPPPADNNLKLLIEGFATFVSRCGKLYEDLSREKNQSNQLFDFLREGNGHDYYARRLWEEQQKRKDQSKLTLDVKVSPTVQKMTAETRGSLLGEKPLQRSLKETDTSASSGGSFQFPTNLSDTFTKSASSQEAADAVKPFKDDPAKQERFEQFLKEKYKGGLRTTDSNRVNSMSESARAQERLDFEAAAEAIEKGKAYKEVRRATEQPLDFLAGGLQFTSGGTEQIKDTGVVDMKSSKTYPKREEFQWRPSPLLCKRFDLPDPFMGKLPPAPRARNKMDSLVFLPDTVKAASARQVSESQVPKKETSIEEPEVEVEVENVERPVDLYKAIFSDDSEDDEDQPMNGKIQEGQEKKNEAAATTLNRLIAGDFLESLGKELGFEVPMEEEIKSRSKPEDSSDKRLDRPGLKEKVEEKTSSLTLGSEEEKSRKKREKSPGKRSGGNDLSSSESSGDERRRKRYNKKDRHRNDSESDSSSDYHSRDKQGSRSRSKRRESSREKRSSHKKHSKHRRTKKSSSSRYSSDEEQKESRREKKRRRD", "length": 930, "molWeight": 104934, "crc64": "D564A8E470F89DF9", "md5": "A6C95256FCAFEB9FACFA6593162E40A1"}}
{"primaryAccession": "Q8GXX0", "text": "This is FAD-linked sulfhydryl oxidase ERV1 protein, from Mouse-ear cress, contains 191 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GXX0", "organism_name": "Mouse-ear cress", "protein_name": "FAD-linked sulfhydryl oxidase ERV1", "length": 191, "firstPublicDate": "2010-11-30", "FUNCTION": "FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation (PubMed:14996837, PubMed:16893552), Oxidizes thioredoxin in vitro (PubMed:14996837, PubMed:16893552), Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space, Forms a redox cycle with MIA40 that involves a disulfide relay system, Important for maintaining the cysteine residues in MIA40 in an oxidized state (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGEKPWQPLLQSFEKLSNCVQTHLSNFIGIKNTPPSSQSTIQNPIISLDSSPPIATNSSSLQKLPLKDKSTGPVTKEDLGRATWTFLHTLAAQYPEKPTRQQKKDVKELMTILSRMYPCRECADHFKEILRSNPAQAGSQEEFSQWLCHVHNTVNRSLGKLVFPCERVDARWGKLECEQKSCDLHGTSMDF", "length": 191, "molWeight": 21600, "crc64": "7CC7FEA44C0D4B38", "md5": "6EE826AA4F0C4CC3488052F2E6AA4231"}}
{"primaryAccession": "Q8GYB1", "text": "This is Nudix hydrolase 15, mitochondrial protein, from Mouse-ear cress, contains 285 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GYB1", "organism_name": "Mouse-ear cress", "protein_name": "Nudix hydrolase 15, mitochondrial", "length": 285, "firstPublicDate": "2005-07-05", "FUNCTION": "Coenzyme A diphosphatase which mediates the cleavage of oxidized CoA, Can use malonyl-CoA, hexanoyl-CoA, lauroyl-CoA, myristoyl-CoA and palmitoyl-CoA as substrates, but not isobutyryl-CoA or propionyl-CoA", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the Nudix hydrolase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFLLYRRLPSFARTTTTTLLCKSMEPAITATSSSSFGGGSSRLAALAQQLRQYKPPPSSSFDDSEEMQTDQETAGKVVSQVGFQESIAPLSKDPDRFKPKRAAVLICLFEGDDGDLRVILTKRSSKLSTHSGEVSLPGGKAEEDDKDDGMTATREAEEEIGLDPSLVDVVTSLEPFLSKHLLRVIPVIGILRDKNKFNPIPNPGEVEAVFDAPLEMFLKDENRRSEEREWMGEKYLIHYFDYRTGDKDYMIWGLTAGILIRAASVTYERPPAFIEQCPKFKYPKM", "length": 285, "molWeight": 31898, "crc64": "C790D52CA9DF2AB8", "md5": "188FFF3E018F2976A7DDDBE16CEFC7F8"}}
{"primaryAccession": "Q8GYD2", "text": "This is Meiotic nuclear division protein 1 homolog protein, from Mouse-ear cress, contains 230 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GYD2", "organism_name": "Mouse-ear cress", "protein_name": "Meiotic nuclear division protein 1 homolog", "length": 230, "firstPublicDate": "2009-06-16", "FUNCTION": "Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis, Stimulates both DMC1/LIM15- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MND1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSKKRGLSLEEKREKMLQIFYESQDFFLLKELEKMGPKKGVISQSVKDVIQSLVDDDLVAKDKIGISIYFWSLPSCAGNQLRSVRQKLESDLQGSNKRLAELVDQCEALKKGREESEERTEALTQLKDIEKKHKDLKNEMVQFADNDPATLEAKRNAIEVAHQSANRWTDNIFTLRQWCSNNFPQAKEQLEHLYTEAGITEDFDYIELSSFPLSSSHEADTAKQLVQDEA", "length": 230, "molWeight": 26403, "crc64": "131BB5146D8C91ED", "md5": "E7C7CAB22022E4EE9D3822462AE93C1B"}}
{"primaryAccession": "Q8GYJ3", "text": "This is Cyclin-dependent kinase inhibitor 4 protein, from Mouse-ear cress, contains 289 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GYJ3", "organism_name": "Mouse-ear cress", "protein_name": "Cyclin-dependent kinase inhibitor 4", "length": 289, "firstPublicDate": "2007-07-10", "FUNCTION": "Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity, May target specifically CDKA-1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CDI family, ICK/KRP subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGKYIRKSKIDGAGAGAGGGGGGGGGGESSIALMDVVSPSSSSSLGVLTRAKSLALQQQQQRCLLQKPSSPSSLPPTSASPNPPSKQKMKKKQQQMNDCGSYLQLRSRRLQKKPPIVVIRSTKRRKQQRRNETCGRNPNPRSNLDSIRGDGSRSDSVSESVVFGKDKDLISEINKDPTFGQNFFDLEEEHTQSFNRTTRESTPCSLIRRPEIMTTPGSSTKLNICVSESNQREDSLSRSHRRRPTTPEMDEFFSGAEEEQQKQFIEKYNFDPVNEQPLPGRFEWTKVDD", "length": 289, "molWeight": 32068, "crc64": "BD7F524A308E11CF", "md5": "97A60FFBDA668008E5D8AACA26102D20"}}
{"primaryAccession": "Q8H191", "text": "This is Probable polyamine oxidase 4 protein, from Mouse-ear cress, contains 497 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8H191", "organism_name": "Mouse-ear cress", "protein_name": "Probable polyamine oxidase 4", "length": 497, "firstPublicDate": "2008-10-14", "FUNCTION": "Flavoenzyme involved in polyamine back-conversion (PubMed:18703589, PubMed:20532512, PubMed:21081665, PubMed:26925084), Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and spermidine (PubMed:18703589, PubMed:20532512, PubMed:21081665, PubMed:26925084), Substrate preference is spermine > spermidine (PubMed:18703589, PubMed:21081665), No activity detected when putrescine or N(1)-acetylspermine are used as substrates (PubMed:18703589), Plays an important role in the regulation of polyamine intracellular concentration (Probable)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the flavin monoamine oxidase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDKKKNSFPDNLPEGTISELMQKQNNVQPSVIVIGSGISGLAAARNLSEASFKVTVLESRDRIGGRIHTDYSFGCPVDMGASWLHGVSDENPLAPIIRRLGLTLYRTSGDDSILYDHDLESYGLFDMHGNKIPPQLVTKVGDAFKRILEETEKIRDETANDMSVLQGISIVLDRNPELRQEGMAYEVLQWYLCRMEAWFAVDANLISLKCWDQDECLSGGHGLMVQGYEPVIRTIAKDLDIRLNHRVTKVVRTSNNKVIVAVEGGTNFVADAVIITVPIGVLKANLIQFEPELPQWKTSAISGLGVGNENKIALRFDRAFWPNVEFLGMVAPTSYACGYFLNLHKATGHPVLVYMAAGNLAQDLEKLSDEATANFVMLQLKKMFPDAPDPAQYLVTRWGTDPNTLGCYAYDVVGMPEDLYPRLGEPVDNIFFGGEAVNVEHQGSAHGAFLAGVSASQNCQRYIFERLGAWEKLKLVSLMGNSDILETATVPLQISRM", "length": 497, "molWeight": 54931, "crc64": "69CEE30B841B022C", "md5": "1852CB67FF20DC0BF272BB9E39DE72D1"}}
{"primaryAccession": "Q8IN44", "text": "This is Protein Turandot A protein, from Fruit fly, contains 129 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IN44", "organism_name": "Fruit fly", "protein_name": "Protein Turandot A", "length": 129, "firstPublicDate": "2008-11-25", "FUNCTION": "A humoral factor that plays a role in stress tolerance; gives increased resistance to the lethal effects of bacterial challenge and stress, Regulated by the JAK/STAT pathway and NF-KB-like Relish pathway in the fat body, upd3 in the hemocytes and Mekk1 in response to septic injury and consequent immune response", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the Turandot family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNSSTALMCFALLLISPLCMGYSDEDREADNLRIAEIIKNAQDDDSKINSTQELLDIYRRLYPSLTPEERESIDKFVNEHTDAIIIDGVPIQGGRKARIVGKIVSPGVKGLATGFFEELGSKLAQLFTG", "length": 129, "molWeight": 14220, "crc64": "FB879758944E5754", "md5": "95261337B1636DFE244F9EFA209F447F"}}
{"primaryAccession": "Q8ISB6", "text": "This is Beta-1,3-glucan-binding protein 2 protein, from Tobacco hawkmoth, contains 482 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8ISB6", "organism_name": "Tobacco hawkmoth", "protein_name": "Beta-1,3-glucan-binding protein 2", "length": 482, "firstPublicDate": "2004-09-27", "FUNCTION": "Involved in the recognition of invading microorganisms, Binds specifically to beta-1,3-glucan and lipoteichoic acid and causes aggregation of invading microorganisms, Binding to beta-1,3-glucan activates the phenoloxidase cascade", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the insect beta-1,3-glucan binding protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MWIKSVCLFATIAGCLGQRGGPYKVPDAKLEAIYPKGLRVSVPDDGYSLFAFHGKLNEEMEGLEAGHWSRDITKAKQGRWIFRDRNAELKLGDKIYFWTYVIKDGLGYRQDNGEWTVTEFVNENGTVVDTSTAPPPVAPAVSEEDQSPGPQWRPCERSLTESLARERVCKGSLVFSEDFDGSSLADLGNWTAEVRFPGEPDYPYNLYTTDGTVGFESGSLVVRPVMTESKYHEGIIYDRLDLERCTGQLGTLECRRESSGGQIVPPVMTAKLATRRSFAFKFGRIDIKAKMPRGDWLIPELNLEPLDNIYGNQRYASGLMRVAFVRGNDVYAKKLYGGPIMSDADPFRSMLLKDKQGLANWNNDYHVYSLLWKPNGLELMVDGEVYGTIDAGDGFYQIAKNNLVSHASQWLKGTVMAPFDEKFFITLGLRVAGIHDFTDGPGKPWENKGTKAMINFWNNRFRWFPTWHDTSLKVDYVRVYAL", "length": 482, "molWeight": 54414, "crc64": "233755F7AD37E8A2", "md5": "5BE520CFA0FFFA38CE950E0D8BBCFBB7"}}
{"primaryAccession": "Q8IV08", "text": "This is 5'-3' exonuclease PLD3 protein, from Human, contains 490 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IV08", "organism_name": "Human", "protein_name": "5'-3' exonuclease PLD3", "length": 490, "firstPublicDate": "2007-03-20", "FUNCTION": "5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (PubMed:30312375), Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity), May be important in myotube formation (PubMed:22428023), Plays a role in lysosomal homeostasis (PubMed:28128235), Involved in the regulation of endosomal protein sorting (PubMed:29368044)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the phospholipase D family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKPKLMYQELKVPAEEPANELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRPAPCYDPCEAVLVESIPEGLDFPNASTGNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQGEEVLRQLQTLAPKGVNVRIAVSKPSGPQPQADLQALLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYDTRYNQETPMEICLNGTPALAYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYVAVMNYLPTLEFSHPHRFWPAIDDGLRRATYERGVKVRLLISCWGHSEPSMRAFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERATYIGTSNWSGNYFTETAGTSLLVTQNGRGGLRSQLEAIFLRDWDSPYSHDLDTSADSVGNACRLL", "length": 490, "molWeight": 54705, "crc64": "444EC4D02F5610F1", "md5": "23111F7CADB3074817BA231F27BAC754"}}
{"primaryAccession": "Q8IVM8", "text": "This is Organic anion transporter 7 protein, from Human, contains 553 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IVM8", "organism_name": "Human", "protein_name": "Organic anion transporter 7", "length": 553, "firstPublicDate": "2006-05-02", "FUNCTION": "Sodium-independent organic anion transporter, exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones such as estrone 3-sulfate (E1S) and dehydroepiandrosterone sulfate (DHEAS) (PubMed:17393504, PubMed:26239079), Can transport the statin pravastatin and may contribute to its disposition into the hepatocytes when the function of OATPs is compromised (PubMed:26239079), It is specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate (propanoate), butyrate (butanoate) and valerate (pentanoate) (PubMed:17393504), May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs, in particular butanoate, at the sinusoidal membrane of hepatocytes (PubMed:17393504)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDTGALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQDEKNERKDPREPKQEDPRVEVTQF", "length": 553, "molWeight": 62169, "crc64": "FE0A1B725FCB7617", "md5": "363E0FAE1DA65D06B3677E1D90A0570C"}}
{"primaryAccession": "Q8IVP5", "text": "This is FUN14 domain-containing protein 1 protein, from Human, contains 155 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IVP5", "organism_name": "Human", "protein_name": "FUN14 domain-containing protein 1", "length": 155, "firstPublicDate": "2007-01-09", "FUNCTION": "Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the FUN14 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATRNPPPQDYESDDDSYEVLDLTEYARRHQWWNRVFGHSSGPMVEKYSVATQIVMGGVTGWCAGFLFQKVGKLAATAVGGGFLLLQIASHSGYVQIDWKRVEKDVNKAKRQIKKRANKAAPEINNLIEEATEFIKQNIVISSGFVGGFLLGLAS", "length": 155, "molWeight": 17178, "crc64": "4E9ABF640795F0A9", "md5": "91F8035D2961CCF0D5CC8B5FCCB6E7F5"}}
{"primaryAccession": "Q8IW35", "text": "This is Centrosomal protein of 97 kDa protein, from Human, contains 865 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IW35", "organism_name": "Human", "protein_name": "Centrosomal protein of 97 kDa", "length": 865, "firstPublicDate": "2006-12-12", "FUNCTION": "Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545, PubMed:30375385), Required for recruitment of CCP110 to the centrosome (PubMed:17719545)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAVARVDAALPPGEGSVVNWSGQGLQKLGPNLPCEADIHTLILDKNQIIKLENLEKCKRLIQLSVANNRLVRMMGVAKLTLLRVLNLPHNSIGCVEGLKELVHLEWLNLAGNNLKAMEQINSCTALQHLDLSDNNISQIGDLSKLVSLKTLLLHGNIITSLRMAPAYLPRSLAILSLAENEIRDLNEISFLASLTELEQLSIMNNPCVMATPSIPGFDYRPYIVSWCLNLRVLDGYVISQKESLKAEWLYSQGKGRAYRPGQHIQLVQYLATVCPLTSTLGLQTAEDAKLEKILSKQRFHQRQLMNQSQNEELSPLVPVETRASLIPEHSSPVQDCQISQESEPVIQVNSWVGINSNDDQLFAVKNNFPASVHTTRYSRNDLHLEDIQTDEDKLNCSLLSSESTFMPVASGLSPLSPTVELRLQGINLGLEDDGVADESVKGLESQVLDKEEEQPLWAANENSVQMMRSEINTEVNEKAGLLPCPEPTIISAILKDDNHSLTFFPESTEQKQSDIKKPENTQPENKETISQATSEKLPMILTQRSVALGQDKVALQKLNDAATKLQACWRGFYARNYNPQAKDVRYEIRLRRMQEHIVCLTDEIRRLRKERDEERIKKFVQEEAFRFLWNQVRSLQVWQQTVDQRLSSWHTDVPPISSTLVPSKHPLFTQSQESSCDQNADWFIASDVAPQEKSLPEFPDSGFHSSLTEQVHSLQHSLDFEKSSTEGSESSIMGNSIDTVRYGKESDLGDVSEEHGEWNKESSNNEQDNSLLEQYLTSVQQLEDADERTNFDTETRDSKLHIACFPVQLDTLSDGASVDESHGISPPLQGEISQTQENSKLNAEVQGQQPECDSTFQLLHVGVTV", "length": 865, "molWeight": 96981, "crc64": "98B1C230DF586DF7", "md5": "C763D549851D6304A12E362B3E61D699"}}
{"primaryAccession": "Q8IWC1", "text": "This is MAP7 domain-containing protein 3 protein, from Human, contains 876 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IWC1", "organism_name": "Human", "protein_name": "MAP7 domain-containing protein 3", "length": 876, "firstPublicDate": "2007-10-02", "FUNCTION": "Promotes the assembly and stability of microtubules", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the MAP7 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMADGAAAGAGGSPSLRELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERREEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPKASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLETVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNNAKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSRPSSKRMTSHTTKTRKADETNTTSRSSAQTKSEGFHDILPKSSDTFRQ", "length": 876, "molWeight": 98429, "crc64": "C149899FB0002B39", "md5": "F6F91C9FC7BC389BC064AD268358BBD5"}}
{"primaryAccession": "Q8IWF2", "text": "This is FAD-dependent oxidoreductase domain-containing protein 2 protein, from Human, contains 684 amino acids, is soluble, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IWF2", "organism_name": "Human", "protein_name": "FAD-dependent oxidoreductase domain-containing protein 2", "length": 684, "firstPublicDate": "2008-05-20", "FUNCTION": "Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD), May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the FOXRED2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFVATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTPKFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAFGKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQLETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLPTEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAESCFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGDQEPLGSPLAPGPLAQSVDSNKEEL", "length": 684, "molWeight": 77791, "crc64": "8209FFAF6289DDAF", "md5": "03C60F88491179775A61339FB55BEA10"}}
{"primaryAccession": "Q8IWX5", "text": "This is Sphingosine-1-phosphate phosphatase 2 protein, from Human, contains 399 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IWX5", "organism_name": "Human", "protein_name": "Sphingosine-1-phosphate phosphatase 2", "length": 399, "firstPublicDate": "2003-10-10", "FUNCTION": "Has specific phosphohydrolase activity towards sphingoid base 1-phosphates, Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro (PubMed:12411432), Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway (By similarity), May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling, May play a role in pro-inflammatory signaling (PubMed:17113265), Plays a role in the regulation of pancreatic islet beta-cell endoplasmic reticulum stress and proliferation (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the type 2 lipid phosphate phosphatase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAELLRSLQDSQLVARFQRRCGLFPAPDEGPRENGADPTERAARVPGVEHLPAANGKGGEAPANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYPFVLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLVSKPAESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLP", "length": 399, "molWeight": 44741, "crc64": "7615BA231263D0B6", "md5": "DA363F6BD43206636FDCB359E0CEA719"}}
{"primaryAccession": "Q8IY49", "text": "This is Monocyte to macrophage differentiation factor 2 protein, from Human, contains 270 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IY49", "organism_name": "Human", "protein_name": "Monocyte to macrophage differentiation factor 2", "length": 270, "firstPublicDate": "2004-08-31", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the ADIPOR family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFAPRLLDFQKTKYARFMNHRVPAHKRYQPTEYEHAANCATHAFWIIPSILGSSNLYFLSDDDWETISAWIYGLGLCGLFVVSTVFHTISWKKSHLRMVEHCLHMFDRMVIYFFIAASYAPWLNLRELGPWASHMRWLVWIMASVGTIYVFFFHERTGSCVQFLRGEACPKAGTACLPARYKLVELLCYVVMGFFPALVILSMPNTEGIWELVTGGVFYCLGMVFFKSDGRIPFAHAIWHLFVAFGAGTHYYAIWRYLYLPSTLQTKVSK", "length": 270, "molWeight": 31264, "crc64": "A726231D6283A2DA", "md5": "0CD915CA0A4002D77C8964775236D3C5"}}
{"primaryAccession": "Q8IYW5", "text": "This is E3 ubiquitin-protein ligase RNF168 protein, from Human, contains 571 amino acids, has 1 RING-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [16, 55], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8IYW5", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase RNF168", "length": 571, "firstPublicDate": "2006-07-11", "FUNCTION": "E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage, Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination, Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates, This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1, Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20/C1orf86 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair, H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates, Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair, Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites, Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region, Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RNF168 family", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPKSEKKSKNKQRNTGDIQKYLTPKSQFGSASHSEAVQEVRKDSVSKDIDSSDRKSPTGQDTEIEDMPTLSPQISLGVGEQGADSSIESPMPWLCACGAEWYHEGNVKTRPSNHGKELCVLSHERPKTRVPYSKETAVMPCGRTESGCAPTSGVTQTNGNNTGETENEESCLLISKEISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEETEINFTQKLIDLEHLLFERHKQEEQDRLLALQLQKEVDKEQMVPNRQKGSPDEYHLRATSSPPDKVLNGQRKNPKDGNFKRQTHTKHPTPERGSRDKNRQVSLKMQLKQSVNRRKMPNSTRDHCKVSKSAHSLQPSISQKSVFQMFQRCTK", "length": 571, "molWeight": 65020, "crc64": "51E16DA92BA654C1", "md5": "BFD43738541101A36ECD87A29BAB7B1D"}}
{"primaryAccession": "Q8IYX3", "text": "This is Coiled-coil domain-containing protein 116 protein, from Human, contains 613 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IYX3", "organism_name": "Human", "protein_name": "Coiled-coil domain-containing protein 116", "length": 613, "firstPublicDate": "2006-10-31", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MARCRHHSGYLADDEASHSMCSARVQLPKKPLVPEMRPACKPGRVPHPPSTCGSSALQGQRRNKRHPQPFGHFLDFLTESQVLDSLETVVEKATERMAAMKTEAGVPLVEVQDPVEVPSGGRRAHARPSLSTVHRHRVRPTLCTGHPNNYPSSSSSMSNCHSSLMAGCLGSHSRDSDLGAQGSLPPVRDKLLLEKNLKRLLQLEREGKGLSQSCSQRDSLLWDSLGSQTSFQWTQEQPLSWFSGLLGSSSGVPEASEPRPGEQEPIFRKREFNKEIKSLLSQLESLDLPGYCPLREPHRTLNFLADHRLFPALQSVVSQAVDKLRGAHCRDGRPLFPTSLEPTSDLPPLGSEPAKPTNGGQPYASPRPTVSSPKMLQRKRKDRGGSPSMSSAQVATRFKLKSPCSSSRFTKKKPLPSISSKSSMSHFSNRLYEELADFLTQQAASLVIRKYEFEKDLSKQLGFFSFPITHVLRDLSLGLKKVKGSRIHLSSETHRSCLLRKLEESKRARQASRLSTSHCSTETPSVQQEPATHTAQDQATEPCRSLYTNLPASRQLSPLEPKLYMSACTGMGSSPPKSKDMDNEGRDKAEIEDEDEDEFKDEDQDEDKDEDGV", "length": 613, "molWeight": 67946, "crc64": "DB4396CBD001BA19", "md5": "B27DAC87ED25702A87D5134429631EA2"}}
{"primaryAccession": "Q8IYY4", "text": "This is Cilium assembly protein DZIP1L protein, from Human, contains 767 amino acids, has 1 C2H2-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [166, 189], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8IYY4", "organism_name": "Human", "protein_name": "Cilium assembly protein DZIP1L", "length": 767, "firstPublicDate": "2008-04-29", "FUNCTION": "Involved in primary cilium formation (PubMed:19852954, PubMed:28530676), Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane (PubMed:28530676)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the DZIP C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQSPAATAEGLSGPLFGAYTFPTFKFQPRHDSMDWRRISTLDVDRVARELDVATLQENIAGITFCNLDREVCSRCGQPVDPALLKVLRLAQLIIEYLLHCQDCLSASVAQLEARLQTSLGQQQRGQQELGRQADELKGVREESRRRRKMISTLQQLLMQTGTHSYHTCHLCDKTFMNATFLRGHIQRRHAGVAEGGKQKKQEQPVEEVLEELRAKLKWTQGELEAQREAERQRQLQEAELIHQREIEAKKEFDKWKEQEWTKLYGEIDKLKKLFWDEFKNVAKQNSTLEEKLRALQSHSVMESKLGSLRDEESEEWLRQARELQALREKTEIQKTEWKRKVKELHEEHMAEKKELQEENQRLQASLSQDQKKAAAQSQCQISTLRAQLQEQARIIASQEEMIQSLSLRKVEGIHKVPKAVDTEEDSPEEEMEDSQDEQHKVLAALRRNPTLLKHFRPILEDTLEEKLESMGIRKDAKGISIQTLRHLESLLRVQREQKARKFSEFLSLRGKLVKEVTSRAKERQENGAVVSQPDGQPSVKSQQSTLVTREAQPKTRTLQVALPSTPAEPPPPTRQSHGSHGSSLTQVSAPAPRPGLHGPSSTPPSSGPGMSTPPFSSEEDSEGDRVQRVSLQPPKVPSRMVPRPKDDWDWSDTETSEENAQPPGQGSGTLVQSMVKNLEKQLEAPAKKPAGGVSLFFMPNAGPQRAATPGRKPQLSEDESDLEISSLEDLPLDLDQREKPKPLSRSKLPEKFGTGPQSSGQPRVPAW", "length": 767, "molWeight": 86848, "crc64": "B491D287A667CCB9", "md5": "40A70558AC20E203D0E6A4CE0D94D3E0"}}
{"primaryAccession": "Q8IZJ1", "text": "This is Netrin receptor UNC5B protein, from Human, contains 945 amino acids, has 1 Ig-like Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [48, 145], "description": "Ig-like", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like Immunoglobulin domain"}, {"location": [147, 242], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "Q8IZJ1", "organism_name": "Human", "protein_name": "Netrin receptor UNC5B", "length": 945, "firstPublicDate": "2004-10-11", "FUNCTION": "Receptor for netrin required for axon guidance, Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding, Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion (By similarity), Functions as netrin receptor that negatively regulates vascular branching during angiogenesis, Mediates retraction of tip cell filopodia on endothelial growth cones in response to netrin (By similarity), It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:12598906), Mediates apoptosis by activating DAPK1, In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the unc-5 family", "domain_description": {"Ig-like Immunoglobulin domain": 1, "Ig-like C2-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGARSGARGALLLALLLCWDPRLSQAGTDSGSEVLPDSFPSAPAEPLPYFLQEPQDAYIVKNKPVELRCRAFPATQIYFKCNGEWVSQNDHVTQEGLDEATGLRVREVQIEVSRQQVEELFGLEDYWCQCVAWSSAGTTKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTICPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQNKKTLSDPNSHLLEASGDAALYAGLVVAIFVVVAILMAVGVVVYRRNCRDFDTDITDSSAALTGGFHPVNFKTARPSNPQLLHPSVPPDLTASAGIYRGPVYALQDSTDKIPMTNSPLLDPLPSLKVKVYSSSTTGSGPGLADGADLLGVLPPGTYPSDFARDTHFLHLRSASLGSQQLLGLPRDPGSSVSGTFGCLGGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTVLSPSVTCGPTGLLLCRPVILTMPHCAEVSARDWIFQLKTQAHQGHWEEVVTLDEETLNTPCYCQLEPRACHILLDQLGTYVFTGESYSRSAVKRLQLAVFAPALCTSLEYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLMFKDSYHNLRLSLHDLPHAHWRSKLLAKYQEIPFYHIWSGSQKALHCTFTLERHSLASTELTCKICVRQVEGEGQIFQLHTTLAETPAGSLDTLCSAPGSTVTTQLGPYAFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFATKASPTGVILDLWEALQQDDGDLNSLASALEEMGKSEMLVAVATDGDC", "length": 945, "molWeight": 103638, "crc64": "56064E335F323447", "md5": "7663229522C0404DA18280355E1AED1D"}}
{"primaryAccession": "Q8IZU0", "text": "This is Protein FAM9B protein, from Human, contains 186 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IZU0", "organism_name": "Human", "protein_name": "Protein FAM9B", "length": 186, "firstPublicDate": "2003-03-25", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the FAM9 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSELDN", "length": 186, "molWeight": 22438, "crc64": "234509A205433927", "md5": "7075CE51876D61023DEBF85B249F0F0F"}}
{"primaryAccession": "Q8J025", "text": "This is Protein APCDD1 protein, from Human, contains 514 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8J025", "organism_name": "Human", "protein_name": "Protein APCDD1", "length": 514, "firstPublicDate": "2006-03-07", "FUNCTION": "Negative regulator of the Wnt signaling pathway, Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin, May act via its interaction with Wnt and LRP proteins, May play a role in colorectal tumorigenesis", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the APCDD1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSWPRRLLLRYLFPALLLHGLGEGSALLHPDSRSHPRSLEKSAWRAFKESQCHHMLKHLHNGARITVQMPPTIEGHWVSTGCEVRSGPEFITRSYRFYHNNTFKAYQFYYGSNRCTNPTYTLIIRGKIRLRQASWIIRGGTEADYQLHNVQVICHTEAVAEKLGQQVNRTCPGFLADGGPWVQDVAYDLWREENGCECTKAVNFAMHELQLIRVEKQYLHHNLDHLVEELFLGDIHTDATQRMFYRPSSYQPPLQNAKNHDHACIACRIIYRSDEHHPPILPPKADLTIGLHGEWVSQRCEVRPEVLFLTRHFIFHDNNNTWEGHYYHYSDPVCKHPTFSIYARGRYSRGVLSSRVMGGTEFVFKVNHMKVTPMDAATASLLNVFNGNECGAEGSWQVGIQQDVTHTNGCVALGIKLPHTEYEIFKMEQDARGRYLLFNGQRPSDGSSPDRPEKRATSYQMPLVQCASSSPRAEDLAEDSGSSLYGRAPGRHTWSLLLAALACLVPLLHWNIRR", "length": 514, "molWeight": 58797, "crc64": "75DA7B8B38E3FFE5", "md5": "738B6E8D94EE7B11DB06DE49EBAC0169"}}
{"primaryAccession": "Q8JZL0", "text": "This is Zinc finger protein 467 protein, from Mouse, contains 594 amino acids, has 12 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [160, 182], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [188, 210], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [216, 238], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [244, 266], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [272, 294], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [300, 322], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [355, 377], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [430, 452], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [458, 480], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [486, 508], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [514, 536], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [542, 564], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8JZL0", "organism_name": "Mouse", "protein_name": "Zinc finger protein 467", "length": 594, "firstPublicDate": "2006-07-25", "FUNCTION": "Transcription factor that promotes adipocyte differentiation and suppresses osteoblast differentiation in the bone marrow, Enhances the osteoclast-supporting ability of stromal cells, Binds with STAT3 the consensus sequence 5'-CTTCTGGGAAGA-3' of the acute phase response element (APRE), Transactivates several promoters including FOS, OSM and PPARG, Recruits a histone deacetylase complex", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 12}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRETLEALNSLGFSVGQPEMAPQSEPRDGFSNAQEKMSSRGESTLHSCSGHETPGQKEGIHTEQAEAPCMGSQASTPQKAEPAGSVPGEEWMIRKVKVEDEDQEAEEEVEWPQHLSFLPSPFPTPDLGQLAVTYKLEPGTPGALGGIALSGWAPIPEKPYGCEECERRFRDQLTLRLHQRLHRGEGPCACPDCGRSFTQRAHMLLHQRSHRGERPFPCSECDKRFSKKAHLTRHLRTHTGERPYPCAECGKRFSQKIHLGSHQKTHTGERPFPCTECEKRFRKKTHLIRHQRIHTGERPYQCTQCTRSFTHKQHLVRHQRVHDAASRTRSSPDIPVAPHSPTASLTPSPPGPKPFACSHCGQSFGWKKNLATHQSLHLTEGRPFGCDECALGTNVDPAAEPSACTPHAPDCGPGSGPAAPQRTTSSERSFFCPDCGRGFAHGQHLARHRRVHTGERPFACAQCGRRFGSRPNLVAHSRAHSGARPFACAQCGRRFSRKSHLGRHQAVHTGSRPHACAVCARCFSSKTNLVRHQAIHTGSRPFSCPQCAKSFSRKTHLVRHQRIHGDAALPAPASNLSAPAWSNPSEVVPPPIFF", "length": 594, "molWeight": 65633, "crc64": "E11EA6416C4A5C6C", "md5": "3CC351953C1DFD110CDFB8C77F32B729"}}
{"primaryAccession": "Q8K0T4", "text": "This is Katanin p60 ATPase-containing subunit A-like 1 protein, from Mouse, contains 488 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8K0T4", "organism_name": "Mouse", "protein_name": "Katanin p60 ATPase-containing subunit A-like 1", "length": 488, "firstPublicDate": "2005-03-01", "FUNCTION": "Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility, Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (PubMed:22654668), Has microtubule-severing activity in vitro (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the AAA ATPase family, Katanin p60 subunit A1 subfamily, A-like 1 sub-subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNLAEICENAKKGREYALLGNYDSSMVYYQGVIQQIQRHCQSLRDPATKAKWQQVRQELLEEYEQVKSIVSTLESFKMDKPPDFPVSCRDEPFRDPAVWPPPVPAEHRAPPQIRRPNREVRPLRKDVGAGARGLVGRAHQISKSDKPASRDKDYRARGRDDKARKNVQDGASDSEIPKFDGAGYDKDLVEALERDIVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPTAKGRAELLKISLREVELDPDVHLEDIADKTEGYSGADITNICRDASLMAMRRRINGLSPEEIRALSKEELQMPVTRGDLELALKKIAKSVSAADLEKYEKWMVEFGSA", "length": 488, "molWeight": 55165, "crc64": "A9BFF34DF2F44BAC", "md5": "54CB730FC706778EF74736B239889D58"}}
{"primaryAccession": "Q8K1M4", "text": "This is Zinc finger protein GLIS1 protein, from Mouse, contains 789 amino acids, has 4 C2H2-type Zinc finger, has 1 C2H2-type 2; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [366, 391], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [400, 427], "description": "C2H2-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 2; atypical Zinc finger"}, {"location": [433, 457], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [463, 487], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [493, 517], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8K1M4", "organism_name": "Mouse", "protein_name": "Zinc finger protein GLIS1", "length": 789, "firstPublicDate": "2004-12-21", "FUNCTION": "Acts as both a repressor and activator of transcription (PubMed:12042312, PubMed:12385751, PubMed:21654807), Binds to the consensus sequence 5'-GACCACCCAC-3' (PubMed:12042312), By controlling the expression of genes involved in cell differentiation inhibits the lineage commitment of multipotent cells (PubMed:21654807, PubMed:30544251), Prevents, for instance, the differentiation of multipotent mesenchymal cells into adipocyte and osteoblast (PubMed:30544251)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the GLI C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 4, "C2H2-type 2; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MHCEVAEALSDKRPKEAPGAPGQGRGPVSLGAHMAFRIAVSGGGCGDGNPLDLLPRLPVPPPRAHDLLRPRSPRDYGVSKTGSGKVNGSYGHSSEKSLLDLDLAEGPSPSCHQGLFLPAGTPPPRGHPPVCEKLLHFPHPNRSPRPQATFVNGSLPAAQHIKQEALPDYQAMVSAHTPLPTHCRAPSSMGLPSDLDFPDRGLTNPAPSCYLLGNEPISDLGPQPEAHLPEGSLKRCCLLGLPPTSSASSSPCASSDINPVIHSSQTALVSCVNGLRSPPLPGDLGGPPKRSRPGPASSDGQEGSLQLEACRKSGFLKQEPMDEFSELFAPHHQGLPPPYPLPQLPTGPGLGGLGLGLAGRMVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHTGADPEADVLSECLSLQQLQASTLLPASRGKGSQTLSQELLPGVYPGSVTPQNGLASGILSPSHDVPSRHHPLEVPTGSHHHLSPLPTAESTRDGLGPSLLSPMVSPLKGLGPPPLPPASQSQSPGGQSFSTVPSKPTYPSFQSPPPLPSPQGYQGSFHSIQNCFPYADCYRATEPAASRDGLVGDAHGFNPLRPSTYSSLSTPLSAPGYETLAETPCPPALQPQPAEDLVPSGPEDCGFFPNGAFDHCLSHIPSIYTDT", "length": 789, "molWeight": 84172, "crc64": "98D87D9EA20D38FD", "md5": "04FAE15B344E24DDBB2462DA24544EC7"}}
{"primaryAccession": "Q8K1S2", "text": "This is Netrin receptor UNC5D protein, from Mouse, contains 956 amino acids, has 1 Ig-like Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [52, 149], "description": "Ig-like", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like Immunoglobulin domain"}, {"location": [151, 242], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "Q8K1S2", "organism_name": "Mouse", "protein_name": "Netrin receptor UNC5D", "length": 956, "firstPublicDate": "2004-10-11", "FUNCTION": "Receptor for the netrin NTN4 that promotes neuronal cell survival (PubMed:21216843), Plays a role in cell-cell adhesion and cell guidance, Receptor for netrin involved in cell migration (By similarity), Plays a role in the regulation of neuronal cell migration in the developing brain via its interaction with FLRT2 (PubMed:21673655), Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (PubMed:21673655), May play a role in apoptosis in response to DNA damage, It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity), Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (PubMed:26235030)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the unc-5 family", "domain_description": {"Ig-like Immunoglobulin domain": 1, "Ig-like C2-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGTGAADGSRGARRWLPWLGLFFWAAGAAAARGADGSEILPDSIPSAPGTLPHFIEEPEDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEESLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTALCPVDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQRWSRRGIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSHSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNPAMQPDLTVSRTYSGPICLQDPLDKELMTESSLFNPLSDIKVKVQSSFMVSLGVSERAEYHGKNHSGTFPHGNNRGFSTIHPRNKTPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSEVLLSPEVTCGPPDMLVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVISDERHQGGQLLEEPKLLHFKGNTFSLQVSVLDIPPFLWRIKPFTACQEVPFSRVWSSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQQDGDLDSLACALEEIGRTHTKLSNITEPQIDDADFNYSRQNGL", "length": 956, "molWeight": 106352, "crc64": "DFDF07839C10C68D", "md5": "3F0DC6AAE10BB28A0541A478F13BCD47"}}
{"primaryAccession": "Q8K1S3", "text": "This is Netrin receptor UNC5B protein, from Mouse, contains 945 amino acids, has 1 Ig-like Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [48, 145], "description": "Ig-like", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like Immunoglobulin domain"}, {"location": [153, 242], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "Q8K1S3", "organism_name": "Mouse", "protein_name": "Netrin receptor UNC5B", "length": 945, "firstPublicDate": "2004-10-11", "FUNCTION": "Receptor for netrin required for axon guidance, Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding, Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion (By similarity), Functions as netrin receptor that negatively regulates vascular branching during angiogenesis (PubMed:15510105), Mediates retraction of tip cell filopodia on endothelial growth cones in response to netrin (PubMed:15510105), It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand, Mediates apoptosis by activating DAPK1, In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the unc-5 family", "domain_description": {"Ig-like Immunoglobulin domain": 1, "Ig-like C2-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRARSGVRSALLLALLLCWDPTPSLAGVDSAGQVLPDSYPSAPAEQLPYFLLEPQDAYIVKNKPVELHCRAFPATQIYFKCNGEWVSQNDHVTQESLDEATGLRVREVQIEVSRQQVEELFGLEDYWCQCVAWSSSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTVCPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCVLNQRTLNDPKSHPLETSGDVALYAGLVVAVFVVVAVLMAVGVIVYRRNCRDFDTDITDSSAALTGGFHPVNFKTARPNNPQLLHPSAPPDLTASAGIYRGPVYALQDSADKIPMTNSPLLDPLPSLKIKVYNSSTIGSGSGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLSLPGTGVSLLVPNGAIPQGKFYDLYLHINKAESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIAGDWIFQLKTQAHQGHWEEVVTLDEETLNTPCYCQLEAKSCHILLDQLGTYVFMGESYSRSAVKRLQLAIFAPALCTSLEYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQRALHCTFTLERHSLASTEFTCKVCVRQVEGEGQIFQLHTTLAETPAGSLDALCSAPGNAITTQLGPYAFKIPLSIRQKICSSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMATDGDC", "length": 945, "molWeight": 103739, "crc64": "80E896F0F0E06012", "md5": "BE5763AE6482BAD76874BA32D907F43D"}}
{"primaryAccession": "Q8K1T0", "text": "This is Transmembrane protease serine 3 protein, from Mouse, contains 453 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8K1T0", "organism_name": "Mouse", "protein_name": "Transmembrane protease serine 3", "length": 453, "firstPublicDate": "2003-05-30", "FUNCTION": "Probable serine protease that plays a role in hearing, Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival, Activates ENaC (in vitro)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGENDPPAAEAPFSFRSLFGLDDLKISPVAPDGDAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCHSSFKCIELTARCDGVSDCKNAEDEYRCVRVSGQRAALQVFTAAAWRTMCSDDWKSHYAKIACAQLGFPSYVSSDHLRVDALEEQFQGDFVSINHLLSDDKVTALHHSVYMREGCTSGHVVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHLCGGSIITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERDLKT", "length": 453, "molWeight": 49506, "crc64": "1EE7ECD6CB3DD894", "md5": "23264D5A3CEEEBC512A663E49286E7B7"}}
{"primaryAccession": "Q8K203", "text": "This is Endonuclease 8-like 3 protein, from Mouse, contains 606 amino acids, has 1 FPG-type Zinc finger, has 1 RanBP2-type Zinc finger, has 2 GRF-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [248, 282], "description": "FPG-type", "keyword_description": "Zinc finger", "textural_description": "FPG-type Zinc finger"}, {"location": [318, 347], "description": "RanBP2-type", "keyword_description": "Zinc finger", "textural_description": "RanBP2-type Zinc finger"}, {"location": [508, 551], "description": "GRF-type", "keyword_description": "Zinc finger", "textural_description": "GRF-type Zinc finger"}, {"location": [555, 597], "description": "GRF-type", "keyword_description": "Zinc finger", "textural_description": "GRF-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8K203", "organism_name": "Mouse", "protein_name": "Endonuclease 8-like 3", "length": 606, "firstPublicDate": "2004-12-07", "FUNCTION": "DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA) (PubMed:20185759, PubMed:22065741, PubMed:22569481, PubMed:22959434, PubMed:23305905, PubMed:23313161), Mediates interstrand cross-link repair in response to replication stress: acts by mediating DNA glycosylase activity, cleaving one of the two N-glycosyl bonds comprising the interstrand cross-link, which avoids the formation of a double-strand break but generates an abasic site that is bypassed by translesion synthesis polymerases (By similarity), In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA (PubMed:20185759, PubMed:22065741, PubMed:22569481, PubMed:22959434, PubMed:23305905, PubMed:23313161), No activity on 8-oxoG detected (PubMed:20185759, PubMed:22065741, PubMed:22569481, PubMed:22959434, PubMed:23305905, PubMed:23313161), Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity (PubMed:20185759, PubMed:22065741, PubMed:22569481, PubMed:22959434, PubMed:23305905, PubMed:23313161), In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues (PubMed:20185759, PubMed:22065741, PubMed:22569481, PubMed:22959434, PubMed:23305905, PubMed:23313161)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the FPG family", "domain_description": {"FPG-type Zinc finger": 1, "RanBP2-type Zinc finger": 1, "GRF-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVEGPGCTLNGEKIRARVLPGQAVTGVRGTALQSLLGPAMSPAASLADVATSAAPMNAKDSGWKLLRLFNGYVYSGVETLGKELFMYFGPRALRIHFGMKGSILINPREGENRAGASPALAVQLTRDLICFYDSSVELRNSVESQQRVRVMEELDICSPKFSFSRAESEVKKQGDRMLCDVLLDQRVLPGVGNIIKNEALFDSGLHPAVKVCQLSDKQACHLVKMTRDFSILFYRCCKAGSAISKHCKVYKRPNCDQCHSKITVCRFGENSRMTYFCPHCQKENPQCVQVCQLPTRNTEISWTPRGEDCFTDSVARKSEEQWSCVVCTLINRPSAKACDACLTTRPLDSVLKNRENSIAFNNLVKYPCNNFENTHTEVKINRKTAFGNTTLVLTDLSNKSSALARKKRANHTIDGESQMFLPTDIGFSDSQHPSKEGINYITQPSNKVNISPTVCAQSKLFSSAHKKFKPAHTSATELKSYNSGLSNSELQTNRTRGHHSKSDGSPLCKMHHRRCVLRVVRKDGENKGRQFYACSLPRGAQCGFFEWADLSFPFCRHGKRSIMKTVLKIGPNNGKNFFVCPLEKKKQCNFFQWAENGPGMEIVPGC", "length": 606, "molWeight": 67416, "crc64": "941C38FA8538BAA8", "md5": "C4942939B315F4C91A619918F1DA713D"}}
{"primaryAccession": "Q8K3P6", "text": "This is Mitochondrial adenyl nucleotide antiporter SLC25A25 protein, from Rat, contains 469 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8K3P6", "organism_name": "Rat", "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A25", "length": 469, "firstPublicDate": "2008-02-05", "FUNCTION": "Electroneutral antiporter that most probably mediates the transport of adenyl nucleotides through the inner mitochondrial membrane, Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it could have a broader specificity for adenyl nucleotides, By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLCLCLYVPIAGEAQTEFQYFESKGLPTELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIIGGFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCAKRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR", "length": 469, "molWeight": 52695, "crc64": "95E5DA46B9942992", "md5": "CF0717A81DA4696B32B88FE3CBFAEC9F"}}
{"primaryAccession": "Q8K3Q3", "text": "This is Forkhead box protein N4 protein, from Mouse, contains 521 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8K3Q3", "organism_name": "Mouse", "protein_name": "Forkhead box protein N4", "length": 521, "firstPublicDate": "2003-01-27", "FUNCTION": "Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively, Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3', During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling, Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis, In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIESGIWSRMSEMIRSSGHSHHCSPQEYRFLPPVGDDDLPGDLQSLSWLTAVDVPRLQQMANGRIDLGSSGVTHPHPGALAGTADLHVGAAPRPLLRRSQTAVVPRGVLGLSPIGNHRASAEQMNQFPAGGQASSGLQEMPQLYSPATQIPFPLPLGSQQCPPAGLYGSPFSARPSYPQAHGAMHASQEPHPKHYPKPIYSYSCLIAMALKNSKTGSLPVSEIYSFMKEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVETKSSGSSRKGCLWALNLARIDKMEEEMHKWKRKDLAAIHRSMANPEELDKLISDRPESCRRPGKRGEPKAPMLTHATTVAMAHSCLAISQLPPKPLMTLSLQSVPLHHQLQPQAHLAPDSPAPAQTPPLHALPSLSPGPLPQPAMGRVPGDFLNINSDMNTEVDALDPSIMDFALQGNLWEEMKEDSFSLDTLEAFGDSPLGCDLGAPSLTPVSGNSDQSFPDVQVTGLYAAYSTAADGVAPSAANSAQYLGTPGNKPIALL", "length": 521, "molWeight": 56121, "crc64": "A5B895C7ED9B2834", "md5": "914BD63F80D784E45CE3E070FD9341CD"}}
{"primaryAccession": "Q8K4G5", "text": "This is Actin-binding LIM protein 1 protein, from Mouse, contains 861 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8K4G5", "organism_name": "Mouse", "protein_name": "Actin-binding LIM protein 1", "length": 861, "firstPublicDate": "2004-12-07", "FUNCTION": "May act as scaffold protein (By similarity), May play a role in the development of the retina, Has been suggested to play a role in axon guidance", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPSLLGLKCLGKLCSSEIGKVPSPERASLRNSHRRLLIEDLSVPETPDPAHRRRGTVIHLVYLYSAGCGPPELRFSSYDPSVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEASCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPPNIPRSSSDFFYPKSLIRRTGRSPALQLLSPPCLTNSNKNPRQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYEDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPELLSPGVHRWSPLRTSSFSSTHSDSRPNPPFRHHFLPHVKGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAVGTDPRRRSSGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERASLASRYDSPLHSASHAPSSKTSSLPGYGKNGLHRPVSTDFAQYNSYGDISGGVRDYQTLPDGHMPAVRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF", "length": 861, "molWeight": 96805, "crc64": "5E045F7CEF1D91EF", "md5": "B532C0857573871E9E547C01F577FCFD"}}
{"primaryAccession": "Q8K4S7", "text": "This is E3 ubiquitin-protein ligase CBL-B protein, from Rat, contains 938 amino acids, has 1 RING-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [373, 412], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8K4S7", "organism_name": "Rat", "protein_name": "E3 ubiquitin-protein ligase CBL-B", "length": 938, "firstPublicDate": "2006-02-07", "FUNCTION": "E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome, Negatively regulates TCR (T-cell receptor), BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways, In naive T-cells, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production, Also acts by promoting PIK3R1/p85 ubiquitination, which impairs its recruitment to the TCR and subsequent activation, In activated T-cells, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy, In B-cells, acts by ubiquitinating SYK and promoting its proteasomal degradation, Slightly promotes SRC ubiquitination, May be involved in EGFR ubiquitination and internalization, May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3, In association with CBL, required for proper feedback inhibition of ciliary platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway via ubiquitination and internalization of PDGFRA (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPFDPRDEGSRCCSIIDPFSIPMLDLDDDDDREESLMMNRLASVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPERPPPIPPDSRLSRHFHHGESVPSRDQPMPLEAWCPRDAFGTNQVMGCRILGDGSPKPGVTANSNLNGRHSRMGSDQVLMRKHRRHDLPSEGAKVFSNGHLAPEEYDVPPRLSPPPPVTALLPSIKCTGPIANCLSEKTRDTVEEDDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHCILNGTHGTPSEMKKSNIPDLGIYLKGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFFDPASGQVPLPPARRAPGDGVKSNRASQDYDQLPSSSDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNLEVARSILREFAFPPPVSPRLNL", "length": 938, "molWeight": 104652, "crc64": "8316D0E7F7252EC6", "md5": "92CAD262E33880A9588283B2CC04E7FB"}}
{"primaryAccession": "Q8K4Z6", "text": "This is G-protein coupled receptor family C group 6 member A protein, from Mouse, contains 928 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8K4Z6", "organism_name": "Mouse", "protein_name": "G-protein coupled receptor family C group 6 member A", "length": 928, "firstPublicDate": "2005-12-06", "FUNCTION": "Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids, The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+), Activated by extracellular calcium and osteocalcin, Seems to act through a G(q)/G(11) and G(i)-coupled pathway, Mediates the non-genomic effects of androgens in multiple tissue, May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MALLITVVTCFMIILDTSQSCHTPDDFVAITSPGHIMIGGLFAIHEKMLSSDDHPRRPQIQKCAGFEISVFLQTLAMIHSIEMINNSTLLSGVKLGYEIYDTCTEVTAAMAATLRFLSKFNCSRETVVFQCDYSSYMPRVKAVIGAGYSETSIAVSRMLNLQLMPQVSYESTAEILSDKIRFPSFLRTVPSDFYQTKAMAHLIRQSGWNWIGAITTDDDYGRLALNTFAIQAAENNVCIAFKEVLPAFLSDNTIEVRINQTLEKIIAEAQVNVIVVFLRKFHVFNLFTKAIERKISKIWIASDNWSTATKIITIPNVKKLGKVVGFAFRRGNTSSFHSFLQTLHMYPNDNNKPLHEFAMLVSACKYIKDGDLSQCISNYSQATLTYDTTKTIENHLFKRNDFLWHYTEPGLIYSIQLAVFALGHAIRDLCQARDCKKPNAFQPWELLAVLKNVTFTDGRNSFHFDAHGDLNTGYDVVLWKETNGLMTVTKMAEYDLQRDVFITTNQETKHEFRKLKQILSKCSKECSPGQMKKATGSQHSCCYECVSCPENHYSNETDMDHCLLCNNETHWAPVRSTTCFEKEVEYLDWDDSLALLLIALSLLGIAFVLAIGIIFTRNLKTPVVKSSGGLVVCYVMLICHALNFASTGFFIGEPQDFACKTRQTLFGVSFTLCVSCILTKSLKILLAFSFDPKLTMFLKCLYRPVPIVLTCTGIQVVICTLWLVLAAPSVEENISLPRVIILECEEGSALAFGTMLGYITVLAFICFVFAFKGRKLPENYNEAKFLTFGMLIYFIAWITFIPVYTTTFGKYLPAVEIIVILISNYGILCCIFFPKCYIILCKQKTNTKSAFLQMVYNYSAHSVDSLALSHVSLDSTSYDTATTNQSPGNKMTACQNDNHLPAQVLPHTGTAKTIKASKTLRQKRSSSI", "length": 928, "molWeight": 104213, "crc64": "D670E3FEC700BD9B", "md5": "150B66115ED1A409815D4134AF0C3F54"}}
{"primaryAccession": "Q8K596", "text": "This is Sodium/calcium exchanger 2 protein, from Mouse, contains 921 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8K596", "organism_name": "Mouse", "protein_name": "Sodium/calcium exchanger 2", "length": 921, "firstPublicDate": "2015-12-09", "FUNCTION": "Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:12818181), Contributes to cellular Ca(2+) homeostasis in excitable cells (PubMed:12818181), Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory (PubMed:12818181), Plays a role in regulating urinary Ca(2+) and Na(+) excretion (PubMed:25498502)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2,A,19) family, SLC8 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPLALMGVVLLLGVPHCLGEATPTPSLPPPTANDSDASPEGCQGSYRCQPGVLLPVWEPEDPSLGDKVARAVVYFVAMVYMFLGVSIIADRFMASIEVITSKEKEITITKANGETSVGTVRIWNETVSNLTLMALGSSAPEILLTVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVCVYVIPAGESRKIKHLRVFFVTASWSIFAYVWLYLILAVFSPGVVQVWEALLTLIFFPVCVVFAWMADKRLLFYKYVYKRYRTDPRSGIIIGAEGDPPKSIELDGTFVGTEVPGELGALGTGPAEARELDASRREVIQILKDLKQKHPDKDLEQLMGIAKYYALLHQQKSRAFYRIQATRLMTGAGNVLRRHAADAARRPGATDGAPDDEDDGASRIFFEPSLYHCLENCGSVLLSVACQGGEGNSTFYVDYRTEDGSAKAGSDYEYSEGTLVFKPGETQKDLRIGIIDDDIFEEDEHFFVRLLNLRVGDAQGMFEPDGGGRPKGRLVAPLLATVTILDDDHAGIFSFQDRLLHVSECMGTVDVRVVRSSGARGTVRLPYRTVDGTARGGGVHYEDACGELEFGDDETMKTLQVKIVDDEEYEKKDNFFIELGQPQWLKRGISALLLNQGNGDKKITAEQEEAQRIAEMGKPVLGENNRLEVIIEESYDFKNTVDKLIKKTNLALVIGTHSWREQFIEAVTVSAGDEEEDEDGPREERLPSCFDYVMHFLTVFWKVLFACVPPTEYCNGWACFGVCILVIGVLTALIGDLASHFGCTVGLKDSVNAVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAAVYWAVQGRPFEVRAGTLAFSVTLFTVFAFVCIAVLLYRRRPQIGGELGGPRGPKLATTALFLGLWFLYILFSSLEAYCHIRGF", "length": 921, "molWeight": 100711, "crc64": "5F5A378FF982073D", "md5": "783DC219DB12C6E795D2B2488541C07E"}}
{"primaryAccession": "Q8L5W8", "text": "This is Transcription factor PIL1 protein, from Mouse-ear cress, contains 416 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8L5W8", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor PIL1", "length": 416, "firstPublicDate": "2008-12-16", "FUNCTION": "Transcription factor, Involved in responses to transient and long-term shade, Required for the light-mediated inhibition of hypocotyl elongation, Necessary for rapid light-induced expression of the photomorphogenesis- and circadian-related gene APRR9, Seems to play a role in multiple PHYB responses, such as flowering transition and petiole elongation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEAKPLASSSSEPNMISPSSNIKPKLKDEDYMELVCENGQILAKIRRPKNNGSFQKQRRQSLLDLYETEYSEGFKKNIKILGDTQVVPVSQSKPQQDKETNEQMNNNKKKLKSSKIEFERNVSKSNKCVESSTLIDVSAKGPKNVEVTTAPPDEQSAAVGRSTELYFASSSKFSRGTSRDLSCCSLKRKYGDIEEEESTYLSNNSDDESDDAKTQVHARTRKPVTKRKRSTEVHKLYERKRRDEFNKKMRALQDLLPNCYKDDKASLLDEAIKYMRTLQLQVQMMSMGNGLIRPPTMLPMGHYSPMGLGMHMGAAATPTSIPQFLPMNVQATGFPGMNNAPPQMLSFLNHPSGLIPNTPIFSPLENCSQPFVVPSCVSQTQATSFTQFPKSASASNLEDAMQYRGSNGFSYYRSPN", "length": 416, "molWeight": 46580, "crc64": "69B86687CC1901CF", "md5": "6C7F64C60653432BA624A100B0B5667B"}}
{"primaryAccession": "Q8L607", "text": "This is Short integuments 2, mitochondrial protein, from Mouse-ear cress, contains 386 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8L607", "organism_name": "Mouse-ear cress", "protein_name": "Short integuments 2, mitochondrial", "length": 386, "firstPublicDate": "2015-04-01", "FUNCTION": "GTPase that may function in mitochondrial ribosome assembly (Probable), Involved in a variety of growth processes during vegetative development and promotes growth and cell division in the developing integuments (PubMed:10835408, PubMed:16849600)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the TRAFAC class YlqF/YawG GTPase family, MTG1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVMMLKKTVKKGLIGGMSFAKDAGKINWFPGHMAAATRAIRNRLKLSDLVIEVRDARIPLSSANEDLQSQMSAKRRIIALNKKDLANPNVLNKWTRHFESSKQDCIAINAHSRSSVMKLLDLVELKLKEVIAREPTLLVMVVGVPNVGKSALINSIHQIAAARFPVQERLKRATVGPLPGVTQDIAGFKIAHRPSIYVLDSPGVLVPSIPDIETGLKLALSGSVKDSVVGEERIAQYFLAILNIRGTPLHWKYLVEGINEGPHADCIDKPSYNLKDLRHQRTKQPDSSALHYVGDMISEVQRSLYITLSEFDGDTEDENDLECLIEQQFEVLQKALKIPHKASEARLMVSKKFLTLFRTGRLGPFILDDVPETETDHPNSKRVVVL", "length": 386, "molWeight": 42984, "crc64": "8E14E12CE24A922F", "md5": "446FBEF8DF9E77F680213615FDF7D749"}}
{"primaryAccession": "Q8L7F7", "text": "This is Nuclear pore complex protein NUP62 protein, from Mouse-ear cress, contains 739 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8L7F7", "organism_name": "Mouse-ear cress", "protein_name": "Nuclear pore complex protein NUP62", "length": 739, "firstPublicDate": "2014-11-26", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the nucleoporin NSP1/NUP62 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGFPFGQSNSVGGFSFGSSSATNSSSASSTTSPLSFSFNQSSNPSSTGFGFGSSVSSTPASSTTPSFGFGASSTPSFGFGSSASSSTPSFGFGSSASVTPASTTPSFGFGTAASSSAPAPSLFGSSTTNASSAAPGSSPFGFVTSSASSTATPSSSLFGAPASSAATPSSSPFGAAPASGSTPLFGSSPSLFSAPSSASASNSSLFGASSSAATSTSPLFGAPSSATGATPSFSVASSAPGSSSSIFGATGSSPSFSVASSASGSSPSIFGATGSSPFFGSSSSAGSTPSLFASSSSGATTSSPSPFGVSTFNSSSTSNTSNASASPFSASTGFSFLKSTASSTTSSTTPSAPPQTASSSSSFSFGTSANSGFNLSTGSSAAPASSTSGAVFSIATTTTTSSSTPAATSAPASSAPASTMAFPSFGVTSSATNTTPASSAATFSTTGFGLASSTPATGSTNSFTGFAVPKTSTPASSSQPQTTSPAFSFSLPSSTSTTAPATSSATTTQTTLVVPSSSGTSTAVAPVAGSPKLPSEITGKTVEEIIKEWNTELQERTGRFRKQANAIAEWDKRILQNRDVLLRLEIEVAKVVETQSSLERQLELIETHQQEVDKALQSMEEEAERIYNDERKSLLDDEAASTRDAMYEQSELVERELEHMTEQIRSIIQSVNANQGGELEAIDGMSPLDVVVRILNNQLSSLMWIDEKAEEFSSRIQKIALQGSGGDRELMAPKHWMS", "length": 739, "molWeight": 73482, "crc64": "CD4DEADB5C786357", "md5": "DEBD674645D31604ACB58CA4FB8D40FB"}}
{"primaryAccession": "Q8L7M0", "text": "This is UDP-glycosyltransferase TURAN protein, from Mouse-ear cress, contains 465 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8L7M0", "organism_name": "Mouse-ear cress", "protein_name": "UDP-glycosyltransferase TURAN", "length": 465, "firstPublicDate": "2015-09-16", "FUNCTION": "Required for pollen tube (PT) growth and integrity by affecting the stability of the pollen-specific ANX1 and ANX2 proteins, Involved in protein N-glycosylation in the endoplasmic reticulum (ER), especially in the female gametophyte, Mediates PT reception in synergids through protein glycosylation", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyltransferase group 1 family, Glycosyltransferase 33 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGKRGRACVVVLGDLGRSPRMQYHALSLARQASFQVDIVAYGGSIPHEAVLNHPSIHIHTMAQPRFIQYFPKILYPVTLLLKAFIQFTMLLWFLFVKVPAPDIFLVQNPPSVPTLIAVKWASSWRRAAFVVDWHNFGYTLLALSLGRNNLLVSLYRWSENHYGKMATGSLCVTKAMQHELDQNWGVRAKVLYDQPPEFFRPALLEERHELFCRVRKDLCHPIGVYDFISRELENQELNETLFTTKFNADISLKQNRPALVVSSTSWTPDENFGILLEAAVMYDRRVAARSKGSETAEISEEQHHYPNLLFIITGKGPEKEMYEEKIKRLNLRHVAFRTMWLAAEDYPLLLGSADLGVCLHTSSSGLDLPMKVVDMFGCGLPVCSVSYSCIQELVKDGKNGLLFSSSSELADQLLILFKGFPGNCDALMSLKAGAMETGSSGRWATEWEDCAKPLITQVVSQIADS", "length": 465, "molWeight": 52321, "crc64": "A507B7E5B6DD971A", "md5": "C1B7A4E11B7CE87204DD61C4A3BFB0AA"}}
{"primaryAccession": "Q8L7W8", "text": "This is Alpha-L-fucosidase 2 protein, from Mouse-ear cress, contains 843 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8L7W8", "organism_name": "Mouse-ear cress", "protein_name": "Alpha-L-fucosidase 2", "length": 843, "firstPublicDate": "2007-05-29", "FUNCTION": "Hydrolyzes alpha-1,2-linked fucose, Also active on fucosylated xyloglucan oligosaccharides, No activity with 3-fucosyllactose, p-nitrophenyl-alpha-I-fucopyranoside, lacto-N-fucopentaose II, lacto-N-fucopentaose III or alpha 1,6-fucosylated chitopentaose, Involved in apoplastic xyloglucan metabolism", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 95 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAEKSSFFVHFSCLLLLLTIIITCGEGVRNPVRPRSSERRALMDGQDLSRPLKLTFGGPSRNWTDAIPIGNGRLGATIWGGVSSEILNINEDTIWTGVPADYTNQKAPEALAEVRRLVDERNYAEATSEAVKLSGQPSDVYQIVGDLNLEFDSSHRKYTQASYRRELDLETAVAKVSYSVGAVDFSREFFASNPDQVIIAKIYASKPGSLSFKVSFDSELHHHSETNPKANQILMRGSCRPKRLPVNLKKSINATNIPYDDHKGLQFASILEVRVSNGGSVSSLGGKKLSVEKADWAVLLLAASSNFDGPFTMPVDSKIDPAKECVNRISSVQKYSYSDLYARHLGDYQKLFNRVSLHLSGSSTNETVQQATSTAERVRSFKTDQDPSLVELLFQYGRYLLISSSRPGTQVANLQGIWNRDIQPPWDGAPHLNINLQMNYWHSLPGNIRECQEPLFDYMSALAINGRKTAQVNYGASGWVAHQVSDIWAKTSPDRGEAVWALWPMGGAWLCTHAWEHYTYTMDKEFLKKKGYPLLEGCTSFLLDWLIKGKDGFLQTNPSTSPEHMFTAPIGKPASVSYSSTMDIAIIKEVFADIVSASEILGKTNDTLIGKVIAAQAKLPPTRISKDGSIREWAEDFEDPEVHHRHVSHLFGLFPGHTITVEKSPELAKAVEATLKKRGEEGPGWSTTWKAALWARLHNSEHAYRMVTHIFDLVDPLNERNYEGGLYSNMFTAHPPFQIDANFGFAAAVAEMLVQSTTKDLYLLPALPADKWPNGIVNGLRARGGVTVSIKWMEGNLVEFGLWSEQIVSTRIVYRGISAAAELLPGKVFTFDKDLRCIRTDKL", "length": 843, "molWeight": 93725, "crc64": "2EF1315DF98A1365", "md5": "542F29D0C5E5005FF63B4BB1076466C4"}}
{"primaryAccession": "Q8L856", "text": "This is Transmembrane ascorbate ferrireductase 1 protein, from Mouse-ear cress, contains 239 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8L856", "organism_name": "Mouse-ear cress", "protein_name": "Transmembrane ascorbate ferrireductase 1", "length": 239, "firstPublicDate": "2011-09-21", "FUNCTION": "Two-heme-containing cytochrome, Catalyzes ascorbate-dependent trans-membrane ferric-chelate reduction, Able to use dihydrolipoic acid (DHLA) as an alternative substrate to ascorbate", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAVRINAMAVTFVAHALAVIAAIMVLVWSISYRGGLAWEATNKNLIFNLHPVLMLIGFIILGGEAIISYKSLPLEKPVKKLIHLILHAIALALGIFGICAAFKNHNESHIPNLYSLHSWIGIGVISLYGFQWVYSFIVFFFPGGSTNLKSGLLPWHAMLGLFVYILAVGNAALGFLEKLTFLENGGLDKYGSEAFLINFTAIITILFGAFVVLTASAESPSPSPSVSNDDSVDFSYSAI", "length": 239, "molWeight": 25865, "crc64": "889543868B994A13", "md5": "6C88526DE38978226D2F820D23D98EB9"}}
{"primaryAccession": "Q8L9A0", "text": "This is Large ribosomal subunit protein bL21m protein, from Mouse-ear cress, contains 270 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8L9A0", "organism_name": "Mouse-ear cress", "protein_name": "Large ribosomal subunit protein bL21m", "length": 270, "firstPublicDate": "2003-04-11", "FUNCTION": "This protein binds to 23S ribosomal RNA in the presence of protein L20 (By similarity), Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus, and during double fertilization of the egg cell and the central cell (PubMed:16698901)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL21 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASLRCFRELSRRATTVFSINQTRSISSFHGIEFSGTSISHGTVIPNRSLTRNLPWYSHWYRSQDRCFSSNTKDTDEDEESSEGEDDDEEEGEDFEDSADMEVEREYSPAEKVEEAEEIGYKVMGPLKPSERLFKPYEPVFAIVQIGSHQFKVSNGDSIFTEKLKFCDINDKLELTKVLLLGSASQTIIGRPILPDATVHAVVEEHALDEKVLIFKKKRRKNYRRTRGHRQELTKLRITDIQGIEKPEPKIVHKPSKEAVTEQTKAELVA", "length": 270, "molWeight": 30908, "crc64": "C83E96E95666ABF9", "md5": "5A386DE3F2DB2F64B72686ED110C9503"}}
{"primaryAccession": "Q8LB10", "text": "This is ATP-dependent Clp protease proteolytic subunit-related protein 4, chloroplastic protein, from Mouse-ear cress, contains 305 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LB10", "organism_name": "Mouse-ear cress", "protein_name": "ATP-dependent Clp protease proteolytic subunit-related protein 4, chloroplastic", "length": 305, "firstPublicDate": "2007-11-13", "FUNCTION": "Involved in plastid protein homeostasis", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the peptidase S14 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEVAAATATSFTTLRARTSAIIPSSTRNLRSKPRFSSSSSLRASLSNGFLSPYTGGSISSDLCGAKLRAESLNPLNFSSSKPKRGVVTMVIPFSKGSAHEQPPPDLASYLFKNRIVYLGMSLVPSVTELILAEFLYLQYEDEEKPIYLYINSTGTTKNGEKLGYDTEAFAIYDVMGYVKPPIFTLCVGNAWGEAALLLTAGAKGNRSALPSSTIMIKQPIARFQGQATDVEIARKEIKHIKTEMVKLYSKHIGKSPEQIEADMKRPKYFSPTEAVEYGIIDKVVYNERGSQDRGVVSDLKKAQLI", "length": 305, "molWeight": 33440, "crc64": "7902D9ECF220B92F", "md5": "CB48D4008D38D6C9F01C3267AA9FA83A"}}
{"primaryAccession": "Q8LBP4", "text": "This is Inner membrane protein ALBINO3, chloroplastic protein, from Mouse-ear cress, contains 462 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LBP4", "organism_name": "Mouse-ear cress", "protein_name": "Inner membrane protein ALBINO3, chloroplastic", "length": 462, "firstPublicDate": "2003-11-14", "FUNCTION": "Required for the insertion of some light harvesting chlorophyll-binding proteins (LHCP) into the chloroplast thylakoid membrane, Required for the insertion of LHCB1, LHCB4,1 and LHCB5 proteins into thylakoid membrane, while it is not required for insertion of proteins PsbX, PsbW and PsbY", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the OXA1/ALB3/YidC (TC 2,A,9,2) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MARVLVSSPSSFFGSPLIKPSSSLRHSGVGGGGTAQFLPYRSNNNKLFTTSTTVRFSLNEIPPFHGLDSSVDIGAIFTRAESLLYTIADAAVVGADSVVTTDSSAVQKSGGWFGFISDAMELVLKILKDGLSAVHVPYAYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPVWIGLYQALSNVANEGLFTEGFFWIPSLGGPTSIAARQSGSGISWLFPFVDGHPPLGWYDTVAYLVLPVLLIASQYVSMEIMKPPQTDDPAQKNTLLVFKFLPLMIGYFALSVPSGLSIYWLTNNVLSTAQQVYLRKLGGAKPNMDENASKIISAGRAKRSIAQPDDAGERFRQLKEQEKRSKKNKAVAKDTVELVEESQSESEEGSDDEEEEAREGALASSTTSKPLPEVGQRRSKRSKRKRTV", "length": 462, "molWeight": 50245, "crc64": "2BBF7AF5BA2E6DDE", "md5": "C35C384D70CD65559FF13EAAFF8737F4"}}
{"primaryAccession": "Q8LD38", "text": "This is Mitochondrial pyruvate carrier 3 protein, from Mouse-ear cress, contains 108 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LD38", "organism_name": "Mouse-ear cress", "protein_name": "Mitochondrial pyruvate carrier 3", "length": 108, "firstPublicDate": "2015-01-07", "FUNCTION": "Mediates the uptake of pyruvate into mitochondria, Negatively regulates ABA-induced guard cell signaling and mediates drought stress responses", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2,A,105) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATSKLQALWNHPAGPKTIHFWAPTFKWGISIANIADFQKPPETLSYPQQIVITGTGLVWSRYSTVITPKNWNLFSVSLGMAVTGIYQLTRKIKHDYVYEANSIVAKE", "length": 108, "molWeight": 12181, "crc64": "59C1805098CFBFA8", "md5": "407ACA51E9B93E2ED1C85D51BE9A8AC8"}}
{"primaryAccession": "Q8LDF9", "text": "This is High mobility group B protein 7 protein, from Mouse-ear cress, contains 241 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LDF9", "organism_name": "Mouse-ear cress", "protein_name": "High mobility group B protein 7", "length": 241, "firstPublicDate": "2010-11-02", "FUNCTION": "Binds preferentially double-stranded supercoiled DNA (PubMed:14756567), Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus (PubMed:16698901)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the HMGB family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGPSTTSNAPKQRKRVEAETSSNTSTTLRRAKDGSAFALCEGCNKSVAVALISMHNCSLDAKIRVNLEAQVVETQAEAKKKPAEKKKTTSDGPKPKRLKKTNDEKKSSSTSNKPKRPLTAFFIFMSDFRKTFKSEHNGSLAKDAAKIGGEKWKSLTEEEKKVYLDKAAELKAEYNKSLESNDADEEEEDEEKQSDDVDDAEEKQVDDDDEVEEKEVENTDDDKKEAEGKEEEEEEILDDY", "length": 241, "molWeight": 26982, "crc64": "C7CE66A84F203855", "md5": "948A6E352D211CB359467F70CE87E2AE"}}
{"primaryAccession": "Q8LDL0", "text": "This is Protein HHL1, chloroplastic protein, from Mouse-ear cress, contains 231 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LDL0", "organism_name": "Mouse-ear cress", "protein_name": "Protein HHL1, chloroplastic", "length": 231, "firstPublicDate": "2015-03-04", "FUNCTION": "Involved in photoprotection, Forms a complex with LQY1 that is involved in the repair and reassembly cycle of the PSII-LHCII supercomplex under high-light conditions, May function in guiding the release of psbC from PSII core monomers", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEVSMSLNALTRLPLKNTGRFEEVGLARHSLFSSRTACRETAVQQRRMVFVVEAKGKKGMAARQYQRTPPPMPKIEDDGNPRFVIFIRMANVYLWYPLSIIAGGTTAKIMVAAKDNLLGKYIYKDTIARNIAAVIYRDEKEIQKTAIKQHRVLRTATEFRYGYKLVENGNMRAALSTSDVIELPTQDQLKTVFDKVKDYFGDAKESFGKLSSLNPGSDEKTEETSDEKAKA", "length": 231, "molWeight": 26081, "crc64": "99271FD460AD5994", "md5": "A3431B874E38B86B1ED11D71F93B79D1"}}
{"primaryAccession": "Q8LE52", "text": "This is Glutathione S-transferase DHAR3, chloroplastic protein, from Mouse-ear cress, contains 258 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LE52", "organism_name": "Mouse-ear cress", "protein_name": "Glutathione S-transferase DHAR3, chloroplastic", "length": 258, "firstPublicDate": "2010-07-13", "FUNCTION": "Displays a dual function, As a soluble protein, exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities (PubMed:12077129), Key component of the ascorbate recycling system, Involved in the redox homeostasis, especially in scavenging of ROS under oxidative stresses (By similarity)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the GST superfamily, DHAR family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MISLRFQPSTTAGVLSASVSRAGFIKRCGSTKPGRVGRFVTMATAASPLEICVKASITTPNKLGDCPFCQKVLLTMEEKNVPYDMKMVDLSNKPEWFLKISPEGKVPVVKFDEKWVPDSDVITQALEEKYPEPPLATPPEKASVGSKIFSTFVGFLKSKDSGDGTEQVLLDELTTFNDYIKDNGPFINGEKISAADLSLAPKLYHMKIALGHYKNWSVPDSLPFVKSYMENVFSRESFTNTRAETEDVIAGWRPKVMG", "length": 258, "molWeight": 28514, "crc64": "35AC1A8EFDD3E77C", "md5": "05F848160B8555956E0F0B8D634CD53A"}}
{"primaryAccession": "Q8LG50", "text": "This is 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 protein, from Mouse-ear cress, contains 389 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LG50", "organism_name": "Mouse-ear cress", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase 2", "length": 389, "firstPublicDate": "2005-05-10", "FUNCTION": "Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position, Has preference for C-18-CoA substrates compared to C-16-CoA substrates, Required for female but not male gametophyte development", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVIAAAVIVPLGLLFFISGLAVNLFQAVCYVLIRPLSKNTYRKINRVVAETLWLELVWIVDWWAGVKIQVFADNETFNRMGKEHALVVCNHRSDIDWLVGWILAQRSGCLGSALAVMKKSSKFLPVIGWSMWFSEYLFLERNWAKDESTLKSGLQRLSDFPRPFWLALFVEGTRFTEAKLKAAQEYAASSELPIPRNVLIPRTKGFVSAVSNMRSFVPAIYDMTVTIPKTSPPPTMLRLFKGQPSVVHVHIKCHSMKDLPESDDAIAQWCRDQFVAKDALLDKHIAADTFPGQQEQNIGRPIKSLAVVLSWACVLTLGAIKFLHWAQLFSSWKGITISALGLGIITLCMQILIRSSQSERSTPAKVVPAKPKDNHHPESSSQTETEKEK", "length": 389, "molWeight": 43676, "crc64": "FA9B7A6F2B786823", "md5": "378C4B25466AE0E8F80C5B2958D6511C"}}
{"primaryAccession": "Q8LGU6", "text": "This is Cell division cycle protein 27 homolog B protein, from Mouse-ear cress, contains 744 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LGU6", "organism_name": "Mouse-ear cress", "protein_name": "Cell division cycle protein 27 homolog B", "length": 744, "firstPublicDate": "2010-08-10", "FUNCTION": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle, The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins, The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation, Involved in the control of endoreduplication, Functionally redundant with CDC27A in the control of gametophyte development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the APC3/CDC27 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEAMLVDCVNNSLRHFVYKNAIFMCERLCAEFPSEVNLQLLATSYLQNNQAYSAYHLLKGTQMAQSRYLFALSCFQMDLLNEAESALCPVNEPGAEIPNGAAGHYLLGLIYKYTDRRKNAAQQFKQSLTIDPLLWAAYEELCILGAAEEATAVFGETAALSIQKQYMQQLSTSLGLNTYNEERNSTSTKNTSSEDYSPRQSKHTQSHGLKDISGNFHSHGVNGGVSNMSFYNTPSPVAAQLSGIAPPPLFRNFQPAVANPNSLITDSSPKSTVNSTLQAPRRKFVDEGKLRKISGRLFSDSGPRRSSRLSADSGANINSSVATVSGNVNNASKYLGGSKLSSLALRSVTLRKGHSWANENMDEGVRGEPFDDSRPNTASTTGSMASNDQEDETMSIGGIAMSSQTITIGVSEILNLLRTLGEGCRLSYMYRCQEALDTYMKLPHKHYNTGWVLSQVGKAYFELIDYLEAEKAFRLARLASPYCLEGMDIYSTVLYHLKEDMKLSYLAQELISTDRLAPQSWCAMGNCYSLQKDHETALKNFLRAVQLNPRFAYAHTLCGHEYTTLEDFENGMKSYQNALRVDTRHYNAWYGLGMIYLRQEKLEFSEHHFRMAFLINPSSSVIMSYLGTSLHALKRSEEALEIMEQAIVADRKNPLPMYQKANILVCLERLDEALEVLEELKEYAPSESSVYALMGRIYKRRNMHDKAMLHFGLALDMKPPATDVAAIKAAMEKLHVPDEIDESP", "length": 744, "molWeight": 83068, "crc64": "1CB1719C75469861", "md5": "7EFA8411E570B1ADC9C7344B70807E5F"}}
{"primaryAccession": "Q8LK61", "text": "This is NADP-dependent glyceraldehyde-3-phosphate dehydrogenase protein, from Wheat, contains 496 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LK61", "organism_name": "Wheat", "protein_name": "NADP-dependent glyceraldehyde-3-phosphate dehydrogenase", "length": 496, "firstPublicDate": "2007-06-26", "FUNCTION": "Important as a means of generating NADPH for biosynthetic reactions", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the aldehyde dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAGTGVFADVLDGEVYKYYADGEWRASASGKTVAIVNPTTRQTQYRVQACTQEEVNKVMDAAKVAQKSWARTPLWKRAELLHKAAAILKEHKTPIAESLVKEIAKPAKDAVSEVVRSGDLVSYTAEEGVRILGEGKLLVSDSFPGNERNKYCLSSKVPLGVVLAIPPFNYPVNLAVSKIGPALIAGNSLVLKPPTQGAVAALHMVHCFHLAGFPKGLISCVTGKGSEIGDFLTMHPGVNCISFTGGDTGIAISKKAGMVPLQMELGGKDACIVLEDADLDLVAANIVKGGFSYSGQRCTAVKVVLIMEAVADTVVEKVNAKLAKLKVGPPEDDSDITPVVTESSANFIEGLVMDAKEKGATFCQEYRREGNLIWPLLLDHVRPDMRIAWEEPFGPVLPVIRINSVEEGIHHCNASNFGLQGCVFTRDINKAIMISDAMESGTVQINSAPARGPDHFPFQGLKDSGIGSQGITNSINMMTKVKSTVINLPSPSYTMG", "length": 496, "molWeight": 53047, "crc64": "F37AB38E8561A287", "md5": "CB55821808BA4223F74279B44217CB66"}}
{"primaryAccession": "Q8LPQ9", "text": "This is Flowering time control protein FPA protein, from Mouse-ear cress, contains 901 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LPQ9", "organism_name": "Mouse-ear cress", "protein_name": "Flowering time control protein FPA", "length": 901, "firstPublicDate": "2010-03-02", "FUNCTION": "Plays a role in the regulation of flowering time in the autonomous flowering pathway by decreasing FLOWERING LOCUS C mRNA levels, Required for RNA-mediated chromatin silencing of a range of loci in the genome, Cotranscriptionally recognizes aberrant RNA and marks it for silencing, Controls alternative cleavage and polyadenylation on pre-mRNAs and antisense RNAs, Acts redundantly with FCA to prevent the expression of distally polyadenylated antisense RNAs at the FLC locus", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RRM Spen family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALSMKPFRADDSGFQSNNLWVGSLTPETTESDLTELFGRYGDIDRITVYSSRGFAFIYYRHVEEAVAAKEALQGANLNGSQIKIEYARPAKPCKSLWVGGIGPNVSKDDLEEEFSKFGKIEDFRFLRERKTAFIDYYEMDDALQAKSMNGKPMGGSFLRVDFLRSQAPKKEQWAGSYDNRNGNMNHKPQYPHSYEDFKGDVQPSKVLWIGFPPTATQCNDEQILHNAMILFGEIERVKSYPSRNFALVEFRSAEEARQCKEGLQGRLFNNPRIKIMYSNDELPPEQDDTSFYSGMKRSRTDMFNNDPSFVSSPHSTGIPGSMRPLRGTNERSYNGAEYNDVVGKEPNWRRPSANGTGILPSPTGPGILPSPAQGTRRPMRSNPDSWEGYDPAQLVRESKRTRRDGSVDGFTPMGVDERSFGRGSVAARPIRGPPDSDHIWRGMIAKGGTPVCCARCVPMGKGIETKLPEVVNCSARTDLNMLAKHYAVAIGCEIVFFVPDREEDFASYTEFLRYLSSKDRAGVAKLDDGTTLFLVPPSDFLTDVLQVTRQERLYGVVLKLPPPAVPVTASYRQESQSNPLHYMDQARDSPANASHSLYPPRENYIRGAPEHLTAASKPSVSEPLRIPNNAAPQAGVSLTPELLATLASILPATSQPAAPESHQPMSGPSTVVSTAHQSNGLYNGEAPSQAWKRGPQTVHDASNQSFQQYGNQYTPAGQLPPPPSRYPPASNNPNYTSGMVHGNMQYQSQSVNMPQLSPLPNMPHNNYSMYTQGSSNHPVSQPMVQQYQPEASMPNQNYGPIPSYQQANFHGVTTNQAQNLNPSQFQAAMQPPADKANLEPQNQALRLQPMISGDGQGTTDGEVDKNQRYQSTLQFAANLLLQIQQKQQQQSSGTPAGQGP", "length": 901, "molWeight": 99598, "crc64": "39E880D9D8FFF355", "md5": "8F88907F4D6B0F6128BBD918A041425C"}}
{"primaryAccession": "Q8MLZ3", "text": "This is cGMP-dependent 3',5'-cGMP phosphodiesterase A protein, from Social amoeba, contains 867 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8MLZ3", "organism_name": "Social amoeba", "protein_name": "cGMP-dependent 3',5'-cGMP phosphodiesterase A", "length": 867, "firstPublicDate": "2008-11-25", "FUNCTION": "Phosphodiesterase specific for cGMP, which is activated by cGMP but not by cAMP (PubMed:12429832, PubMed:12429831) (Probable), Involved in the degradation of intracellular cGMP, contributes to the control of cGMP signals (PubMed:12198158, PubMed:12429832)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the metallo-beta-lactamase superfamily, cNMP phosphodiesterase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMFSKRKSIRFNPEGDYTELPRGGYVVPSKLGGIQFGVPPETIKDSMALKIDVPTIYVFPEELWDRKTGINAAEAEFPAYFNYFILKRKVSFVCTKEQEQRIRIVFQETLLGPPEFNTGIIINSSSSTTDTSKTSPIKKQTSSSSPPLSPQQQQPPPPLVKQPSQQQLEELATMDTCHYHHHHHHQEVNDNDNNNNTTTNNNNIEILEQQQQQQQQQQQQQDEDSTDVDEEFQKEFSSTFPRSEIPNLEKECKYLRTFNSVDELFDFILFDDNGIAKLSDDVEIHFQEDQSLFKVLQFEETGKGNKVQTLVATIPSKILFPDMINSISTINDNKIFDPPTFGITIIGSSHGFDPKKSTTGFVLWINKRGIMVDPPLNSSSFLQSQGVPTRMVDHIILTHCHADHDSGTFQKLLEEYQITVVTTPTILGSFLRKYGALSNLSTDLLRRLFIFRPVMIGEPMIISGAEFRFFYTIHTIPTISFEVFYGGKSIFYSGDTCYDPNRIKDMNKRGIMKTSRMKFFLRPWNHTVVLHEAGVPPIHTPVSVLRALPDEVKNRLYLVHISEHTLPAGSGLKIAKEGVAHTLSLDVMKSSHSEAVDILKLVESVDIFRSIPLTQACEILQTATKRKYSQGSVIIARDTEPDAFYVVASGVVCVNIGELKKNLIVGDYFGEMSLVMGGLRSANVQAVTDVEVLSFNKEDFLSITRNSTESIQFITRLWEMRNEKSWETMSLNSVFSRCTNSQKTAIQSILVRELIKKDETLWCKGEEALFGCLVAEGSFVFKEDDSLESFSQGSFLGDINAMTTQPPSIHKTTVVAKEESVIYKVLSQDLIKFFSNNPGIQLAFLDTIFVDALRDQVQQLVNSKLTY", "length": 867, "molWeight": 97992, "crc64": "E203EED614E6F386", "md5": "716EA61367D119DB3C0B68A786287BED"}}
{"primaryAccession": "Q8MQ70", "text": "This is Homeodomain-interacting protein kinase 1 protein, from Caenorhabditis elegans, contains 846 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8MQ70", "organism_name": "Caenorhabditis elegans", "protein_name": "Homeodomain-interacting protein kinase 1", "length": 846, "firstPublicDate": "2015-04-29", "FUNCTION": "Serine/threonine-protein kinase required in the somatic gonadal cells to regulate germline proliferation during larval development and in adulthood (PubMed:23904186), Plays a role in the development/differentiation of gonadal distal tip cells (PubMed:23904186), Required for normal lifespan in a pha-4 and mxl-2-dependent manner (PubMed:26791749, PubMed:29036198, PubMed:36173858), Also contributes to survival following heat or oxidative stress (PubMed:26791749), Prevents sumoylation and inactivation of heat shock transcription factor hsf-1 which enhances hsf-1-dependent transcriptional induction of chaperones in response to heat shock (PubMed:29036198), Also required for hormetic extension of longevity in response to heat stress (PubMed:29036198), Provides protection against polyglutamine aggregate formation and associated locomotory toxicity (PubMed:29036198), Also contributes to longevity by promoting autophagy under nutrient stress conditions through induction of autophagosome formation and autophagy gene expression (PubMed:29036198)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, HIPK subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPKRKNSGQSTDLNSRSPKTIDEALRILAPPQALLVQSQLNLTAPANPFSIQKAPGTSSDNEQRAPKRRADEEAVNAVPKNLLTTSSTFARAVIPAAPAISSANNKMAPQSVTATAKTTTNRGKVSGEGEYQLIKNEVLCSPYGNQYEVLEFLGKGTFGQVVKAWKKGTSEIVAIKILKKHPSYARQGQIEVSILSRLSNENSEEFNFVRAFECFNHKSHTCLVFEMLEQNLYDFLKQNKFMPLPLNAIRPILFQVLTALLKLKSLGLIHADLKPENIMLVDPQQQPYRVKVIDFGSASHRSKAVTNTYLQSRYYRAPEIILGLPFNESIDMWSLGCVIAELFLGWPLYPGSSEYDQIRFIIQTQGLPPTSMLESASKLHRFFKEVKSESPNHTNVGGSYYRLKTVEEYEASSSTAKSKETRKYIFNVIDDISRVCYGFESDPVEHLCDRIDRQEFVDVLKKMLVLNPDFRITPAEGLESKFVTMTHINGYNFANYVHEAHKRMEICRKPGPAMATPYRAANVATPITPVEKPPAPKLQQPMIAVLPQLNQIAATNIPPVPTQPDLTNLMHHYSQMAAATGSAATAAQFFYQPLPPAPLFQYAQLHHPFAARPPHFLSLATPSHMVPQFVPVPIMDPSMLQGQWPPGAAQQFAVLANDIMRVPAPQGINQMFASTPQTFSLPQFLSSSIPSATTAFNGNAPNIPFPEENSSWALGTAAQQQQQQAQRAQSMINGNVKVKPLAAQPKKNSPAPSVITLSSDEDSNGAGSSNSGSTTRTGAVNPVRNDTLPMGNTIKTEDILVPPTTFDGQLPNLQYFPGSHLFDPKTVAGLLPNPFLDTSHIPRAFN", "length": 846, "molWeight": 93228, "crc64": "946D937A5F568951", "md5": "396386BEB4896341624B386AED9A284B"}}
{"primaryAccession": "Q8MU95", "text": "This is Beta-1,3-glucan-binding protein protein, from Indianmeal moth, contains 488 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8MU95", "organism_name": "Indianmeal moth", "protein_name": "Beta-1,3-glucan-binding protein", "length": 488, "firstPublicDate": "2004-09-27", "FUNCTION": "Involved in the recognition of invading microorganisms causing their aggregation (PubMed:12770576, PubMed:15084591), Activates the phenoloxidase cascade (PubMed:12770576, PubMed:15084591, PubMed:23237493), Binds specifically to beta-1,3-glucan (PubMed:12770576, PubMed:15084591, PubMed:21697086, PubMed:23237493), Binds to curdlan, a linear water-insoluble beta-1,3-glucan polysaccharide, and to laminarin, a water-soluble beta-1,3-glucan polysaccharide containing beta-1,6 branches (PubMed:15084591, PubMed:21697086, PubMed:23237493), Binds also to lipopolysaccharide and lipoteichoic acid (PubMed:15084591)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the insect beta-1,3-glucan binding protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFVTFICFLACLTCSYGQPRAQQYVVPSAKLEAIYPKGLRVSIPDDGFSLFAFHGKLNEEMDGLEAGHWARDITKPKEGRWTFRDRNVKLKLGDKIYFWTYVIKDGLGYRQDNGEWTVTEFVNEDGTPADTSLEPTTAPTPVRPDQPNQPIPTHRPDPPCTVSATMVDGRKSVCQGTLLFSEEFEKANLKDLANWEAEVKFPEEPDYPFNVYMVDGTLELEDGSLVLTPKLLESRFHAGILNDALDLTNRCSGQVDTTECRRQASGAQILPPVMTGKITTKNKFTFKFGRVEVRAKLPAGNWLLPEINLEPKDNVFGSRRYESGLMRVAFAKGNAVFAKKLNGGPVLADTEPFRSLLMKEKIGIDNWNRDYHNYTLIWKQDGIDMLVDGEKYGSISPGEGFYALGREHAVPHAAHWLRGSVMAPLDQYFFLSLGLRVGGVHDFADSPDKPWKNRSNKAVLNFWNDRDNWFPTWFDANLKVDYVRVYAL", "length": 488, "molWeight": 55213, "crc64": "38E21D6C94D446F5", "md5": "3B54318F42E6865341C0F2582AAE37F3"}}
{"primaryAccession": "Q8N1Q8", "text": "This is Acyl-coenzyme A thioesterase THEM5 protein, from Human, contains 247 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N1Q8", "organism_name": "Human", "protein_name": "Acyl-coenzyme A thioesterase THEM5", "length": 247, "firstPublicDate": "2007-04-17", "FUNCTION": "Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleoyl-CoA and other unsaturated long-chain fatty acid-CoA esters (PubMed:22586271), Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin (PubMed:22586271), Required for normal mitochondrial function (PubMed:22586271)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the THEM4/THEM5 thioesterase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIRRCFQVAARLGHHRGLLEAPRILPRLNPASAFGSSTDSMFSRFLPEKTDLKDYALPNASWCSDMLSLYQEFLEKTKSSGWIKLPSFKSNRDHIRGLKLPSGLAVSSDKGDCRIFTRCIQVEGQGFEYVIFFQPTQKKSVCLFQPGSYLEGPPGFAHGGSLAAMMDETFSKTAFLAGEGLFTLSLNIRFKNLIPVDSLVVMDVELDKIEDQKLYMSCIAHSRDQQTVYAKSSGVFLQLQLEEESPQ", "length": 247, "molWeight": 27677, "crc64": "55117AE70FFC183F", "md5": "56BC9FB8371FD5D32EE614BA12BF4F23"}}
{"primaryAccession": "Q8N2A8", "text": "This is Mitochondrial cardiolipin hydrolase protein, from Human, contains 252 amino acids, has 1 C3H1-type; atypical Zinc finger, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [{"location": [45, 78], "description": "C3H1-type; atypical", "keyword_description": "Zinc finger", "textural_description": "C3H1-type; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q8N2A8", "organism_name": "Human", "protein_name": "Mitochondrial cardiolipin hydrolase", "length": 252, "firstPublicDate": "2008-03-18", "FUNCTION": "Presents phospholipase and nuclease activities, depending on the different physiological conditions (PubMed:17028579, PubMed:21397847, PubMed:28063496), Interaction with Mitoguardin (MIGA1 or MIGA2) affects the dimer conformation, facilitating the lipase activity over the nuclease activity (PubMed:26711011), Plays a key role in mitochondrial fusion and fission via its phospholipase activity (PubMed:17028579, PubMed:24599962, PubMed:26678338), In its phospholipase role, it uses the mitochondrial lipid cardiolipin as substrate to generate phosphatidate (PA or 1,2-diacyl-sn-glycero-3-phosphate), a second messenger signaling lipid (PubMed:17028579, PubMed:26711011), Production of PA facilitates Mitofusin-mediated fusion, whereas the cleavage of PA by the Lipin family of phosphatases produces diacylgycerol (DAG) which promotes mitochondrial fission (PubMed:24599962), Both Lipin and DAG regulate mitochondrial dynamics and membrane fusion/fission, important processes for adapting mitochondrial metabolism to changes in cell physiology, Mitochondrial fusion enables cells to cope with the increased nucleotide demand during DNA synthesis (PubMed:26678338), Mitochondrial function and dynamics are closely associated with biological processes such as cell growth, proliferation, and differentiation (PubMed:21397848), Mediator of MYC activity, promotes mitochondrial fusion and activates AMPK which in turn inhibits YAP/TAZ, thereby inducing cell growth and proliferation (PubMed:26678338), The endonuclease activity plays a critical role in PIWI-interacting RNA (piRNA) biogenesis during spermatogenesis (PubMed:21397847, PubMed:21397848), Implicated in spermatogenesis and sperm fertility in testicular germ cells, its single strand-specific nuclease activity is critical for the biogenesis/maturation of PIWI-interacting RNA (piRNA), MOV10L1 selectively binds to piRNA precursors and funnels them to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins, Cleaves either DNA or RNA substrates with similar affinity, producing a 5' phosphate end, in this way it participates in the processing of primary piRNA transcripts, piRNAs provide essential protection against the activity of mobile genetic elements, piRNA-mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation (By similarity), PA may act as signaling molecule in the recognition/transport of the precursor RNAs of primary piRNAs (PubMed:21397847), Interacts with tesmin in testes, suggesting a role in spermatogenesis via association with its interacting partner (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the phospholipase D family, MitoPLD/Zucchini subfamily", "domain_description": {"C3H1-type; atypical Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGRLSWQVAAAAAVGLALTLEALPWVLRWLRSRRRRPRREALFFPSQVTCTEALLRAPGAELAELPEGCPCGLPHGESALSRLLRALLAARASLDLCLFAFSSPQLGRAVQLLHQRGVRVRVVTDCDYMALNGSQIGLLRKAGIQVRHDQDPGYMHHKFAIVDKRVLITGSLNWTTQAIQNNRENVLITEDDEYVRLFLEEFERIWEQFNPTKYTFFPPKKSHGSCAPPVSRAGGRLLSWHRTCGTSSESQT", "length": 252, "molWeight": 28273, "crc64": "CE3A205C1D42B497", "md5": "28B925A9823FFD3B721B8B6106249DE4"}}
{"primaryAccession": "Q8N2F6", "text": "This is Armadillo repeat-containing protein 10 protein, from Human, contains 343 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N2F6", "organism_name": "Human", "protein_name": "Armadillo repeat-containing protein 10", "length": 343, "firstPublicDate": "2007-08-21", "FUNCTION": "May play a role in cell survival and cell growth, May suppress the transcriptional activity of p53/TP53", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSSKSAGALEEGTSEGQLCGRSARPQTGGTWESQWSKTSQPEDLTDGSYDDVLNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDHQHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVDHHDAEVKEKVVTIIPKI", "length": 343, "molWeight": 37540, "crc64": "8DCA090DF3BBE759", "md5": "3E05897594B004B5A0EB7DA503FBE576"}}
{"primaryAccession": "Q8N2Z9", "text": "This is Centromere protein S protein, from Human, contains 138 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N2Z9", "organism_name": "Human", "protein_name": "Centromere protein S", "length": 138, "firstPublicDate": "2006-09-19", "FUNCTION": "DNA-binding component of the Fanconi anemia (FA) core complex, Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage (PubMed:20347428, PubMed:20347429), In complex with CENPX (MHF heterodimer), crucial cofactor for FANCM in both binding and ATP-dependent remodeling of DNA, Stabilizes FANCM (PubMed:20347428, PubMed:20347429), In complex with CENPX and FANCM (but not other FANC proteins), rapidly recruited to blocked forks and promotes gene conversion at blocked replication forks (PubMed:20347428), In complex with CENPT, CENPW and CENPX (CENP-T-W-S-X heterotetramer), involved in the formation of a functional kinetochore outer plate, which is essential for kinetochore-microtubule attachment and faithful mitotic progression (PubMed:19620631), As a component of MHF and CENP-T-W-S-X complexes, binds DNA and bends it to form a nucleosome-like structure (PubMed:20347428, PubMed:22304917), DNA-binding function is fulfilled in the presence of CENPX, with the following preference for DNA substates: Holliday junction > double-stranded > splay arm > single-stranded, Does not bind DNA on its own (PubMed:20347428, PubMed:20347429)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TAF9 family, CENP-S/MHF1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEEEAETEEQQRFSYQQRLKAAVHYTVGCLCEEVALDKEMQFSKQTIAAISELTFRQCENFAKDLEMFARHAKRTTINTEDVKLLARRSNSLLKYITDKSEEIAQINLERKAQKKKKSEDGSKNSRQPAEAGVVESEN", "length": 138, "molWeight": 15893, "crc64": "CBCD22CDDE213D87", "md5": "C38777C600011495279A1864779DC9DF"}}
{"primaryAccession": "Q8N3G9", "text": "This is Transmembrane protein 130 protein, from Human, contains 435 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N3G9", "organism_name": "Human", "protein_name": "Transmembrane protein 130", "length": 435, "firstPublicDate": "2007-02-20", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAQAVWSRLGRILWLACLLPWAPAGVAAGLYELNLTTDSPATTGAVVTISASLVAKDNGSLALPADAHLYRFHWIHTPLVLTGKMEKGLSSTIRVVGHVPGEFPVSVWVTAADCWMCQPVARGFVVLPITEFLVGDLVVTQNTSLPWPSSYLTKTVLKVSFLLHDPSNFLKTALFLYSWDFGDGTQMVTEDSVVYYNYSIIGTFTVKLKVVAEWEEVEPDATRAVKQKTGDFSASLKLQETLRGIQVLGPTLIQTFQKMTVTLNFLGSPPLTVCWRLKPECLPLEEGECHPVSVASTAYNLTHTFRDPGDYCFSIRAENIISKTHQYHKIQVWPSRIQPAVFAFPCATLITVMLAFIMYMTLRNATQQKDMVEVADFDFSPMSDKNPEPPSGVRCCCQMCCGPFLLETPSEYLEIVRENHGLLPPLYKSVKTYTV", "length": 435, "molWeight": 48329, "crc64": "737509A3F8263A4F", "md5": "21C90F39927789F7197DD300A950267C"}}
{"primaryAccession": "Q8N427", "text": "This is Thioredoxin domain-containing protein 3 protein, from Human, contains 588 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N427", "organism_name": "Human", "protein_name": "Thioredoxin domain-containing protein 3", "length": 588, "firstPublicDate": "2005-07-05", "FUNCTION": "Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs, May be involved in the reduction of disulfide bonds within the sperm FS components, In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "In the C-terminal section; belongs to the NDK family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASKKREVQLQTVINNQSLWDEMLQNKGLTVIDVYQAWCGPCRAMQPLFRKLKNELNEDEILHFAVAEADNIVTLQPFRDKCEPVFLFSVNGKIIEKIQGANAPLVNKKVINLIDEERKIAAGEMARPQYPEIPLVDSDSEVSEESPCESVQELYSIAIIKPDAVISKKVLEIKRKITKAGFIIEAEHKTVLTEEQVVNFYSRIADQCDFEEFVSFMTSGLSYILVVSQGSKHNPPSEETEPQTDTEPNERSEDQPEVEAQVTPGMMKNKQDSLQEYLERQHLAQLCDIEEDAANVAKFMDAFFPDFKKMKSMKLEKTLALLRPNLFHERKDDVLRIIKDEDFKILEQRQVVLSEKEAQALCKEYENEDYFNKLIENMTSGPSLALVLLRDNGLQYWKQLLGPRTVEEAIEYFPESLCAQFAMDSLPVNQLYGSDSLETAEREIQHFFPLQSTLGLIKPHATSEQREQILKIVKEAGFDLTQVKKMFLTPEQIEKIYPKVTGKDFYKDLLEMLSVGPSMVMILTKWNAVAEWRRLMGPTDPEEAKLLSPDSIRAQFGISKLKNIVHGASNAYEAKEVVNRLFEDPEEN", "length": 588, "molWeight": 67270, "crc64": "161A5101E06EE5A7", "md5": "8F93D3965D41927EFF46C7F6E4F565FE"}}
{"primaryAccession": "Q8N4T0", "text": "This is Carboxypeptidase A6 protein, from Human, contains 437 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N4T0", "organism_name": "Human", "protein_name": "Carboxypeptidase A6", "length": 437, "firstPublicDate": "2003-11-07", "FUNCTION": "May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas, May convert inactive angiotensin I into the biologically active angiotensin II (PubMed:18178555), Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine (PubMed:20855895)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKKCP", "length": 437, "molWeight": 51008, "crc64": "9C21780D4B7D0A98", "md5": "26E167111F28BD788CA7786E5AAD1D7A"}}
{"primaryAccession": "Q8N4X5", "text": "This is Actin filament-associated protein 1-like 2 protein, from Human, contains 818 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N4X5", "organism_name": "Human", "protein_name": "Actin filament-associated protein 1-like 2", "length": 818, "firstPublicDate": "2005-06-21", "FUNCTION": "May play a role in a signaling cascade by enhancing the kinase activity of SRC, Contributes to SRC-regulated transcription activation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKVTINKQQNAESQGKAPEEQGLLPNGEPSQHSSAPQKSLPDLPPPKMIPERKQLAIPKTESPEGYYEEAEPYDTSLNEDGEAVSSSYESYDEEDGSKGKSAPYQWPSPEAGIELMRDARICAFLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLKITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEKYLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQDRQEELYDDVDLSELTAAVEPTEEATPVADDPNERESDRVYLDLTPVKSFLHGPSSAQAQASSPTLSCLDNATEALPADSGPGPTPDEPCIKCPENLGEQQLESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVTSAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLENVSPRPKAVTPASAPDCTPVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS", "length": 818, "molWeight": 91300, "crc64": "36040D6D09491DA8", "md5": "8E4D9272DA289BE8F3D103D6DF4469F3"}}
{"primaryAccession": "Q8N556", "text": "This is Actin filament-associated protein 1 protein, from Human, contains 730 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N556", "organism_name": "Human", "protein_name": "Actin filament-associated protein 1", "length": 730, "firstPublicDate": "2008-02-05", "FUNCTION": "Can cross-link actin filaments into both network and bundle structures (By similarity), May modulate changes in actin filament integrity and induce lamellipodia formation, May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton, Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKAELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSLKGKKPPVASNGVTGKGKTLSSQPKKADPAAVVKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKALAGGVTLGLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDTEGPVPVNSAAVLKKSQAAPGSSPCRGHVLRKAKEWELKNGT", "length": 730, "molWeight": 80725, "crc64": "4E916BB4F82F5547", "md5": "9A92C117A5AC7AB5B7832C77C09AC0E3"}}
{"primaryAccession": "Q8N573", "text": "This is Oxidation resistance protein 1 protein, from Human, contains 874 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N573", "organism_name": "Human", "protein_name": "Oxidation resistance protein 1", "length": 874, "firstPublicDate": "2006-04-04", "FUNCTION": "May be involved in protection from oxidative damage", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the OXR1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTKDKNSPGLKKKSQSVDINAPGFNPLAGAGKQTPQASKPPAPKTPIIEEEQNNAANTQKHPSRRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEVVSVAEYHRRIDALNTEELRTLCRRLQITTREDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE", "length": 874, "molWeight": 97970, "crc64": "4231D07369CE2D36", "md5": "9721D365A40877A1FF7654B802658E76"}}
{"primaryAccession": "Q8N5M9", "text": "This is Protein jagunal homolog 1 protein, from Human, contains 183 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N5M9", "organism_name": "Human", "protein_name": "Protein jagunal homolog 1", "length": 183, "firstPublicDate": "2008-01-15", "FUNCTION": "Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function, Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport, Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway; possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the jagunal family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKMSVGHLRLLSHDQVAMPYQWEYPYLLSILPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKAYRFLFGFSAVSIMYLVLVLAVQVHAWQLYYSKKLLDSWFTSTQEKKHK", "length": 183, "molWeight": 21125, "crc64": "5F203B99E670D7A7", "md5": "B474937B0D649C75C035C55355D0626C"}}
{"primaryAccession": "Q8N5Z5", "text": "This is BTB/POZ domain-containing protein KCTD17 protein, from Human, contains 321 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N5Z5", "organism_name": "Human", "protein_name": "BTB/POZ domain-containing protein KCTD17", "length": 321, "firstPublicDate": "2006-07-25", "FUNCTION": "Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension, It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598), May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQTPRPAMRMEAGEAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRMEEKDYTVTQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSSYNYGSEDQAEFLCVVSKELHSTPNGLSSESSRKTKSTEEQLEEQQQQEEEVEEVEVEQVQVEADAQEKAQSSQDPANLFSLPPLPPPPLPAGGSRPHPLRPEAELAVRASPRPLARPQSCHPCCYKPEAPGCEAPDHLQGLGVPI", "length": 321, "molWeight": 35670, "crc64": "DB80D4B4BD8CB7E7", "md5": "25FAC8262F7DBF04A66F4612CC5D9855"}}
{"primaryAccession": "Q8N695", "text": "This is Sodium-coupled monocarboxylate transporter 1 protein, from Human, contains 610 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N695", "organism_name": "Human", "protein_name": "Sodium-coupled monocarboxylate transporter 1", "length": 610, "firstPublicDate": "2008-05-20", "FUNCTION": "Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1 (PubMed:14966140, PubMed:15090606, PubMed:17178845, PubMed:16805814, PubMed:16729224, PubMed:17526579, PubMed:17245649, PubMed:20211600, PubMed:30604288), Catalyzes passive carrier mediated diffusion of iodide (PubMed:12107270), Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane (PubMed:12107270), May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract (PubMed:17245649), Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines (PubMed:12829793, PubMed:15867356, PubMed:18037591), May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons (PubMed:16805814), Mediates sodium-coupled electrogenic transport of pyroglutamate (5-oxo-L-proline) (PubMed:20211600), Can mediate the transport of chloride, bromide, iodide and nitrate ions when the external concentration of sodium ions is reduced (PubMed:19864324)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the sodium:solute symporter (SSF) (TC 2,A,21) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDTPRGIGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFNKCVRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIGAQIYPPLPERTLPLHLDIQGCNSTYNETNLMTTTEMPFTTSVFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVGILVSLSTGGRKQNLDPRYILTKEDFLSNFDIFKKKKHVLSYKSHPVEDGGTDNPAFNHIELNSDQSGKSNGTRL", "length": 610, "molWeight": 66578, "crc64": "47FF410B895DB692", "md5": "209E8F11489DBD9577825BBC3A6CD021"}}
{"primaryAccession": "Q8N6S4", "text": "This is Ankyrin repeat domain-containing protein 13C protein, from Human, contains 541 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N6S4", "organism_name": "Human", "protein_name": "Ankyrin repeat domain-containing protein 13C", "length": 541, "firstPublicDate": "2006-06-27", "FUNCTION": "Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTGEKIRSLRRDHKPSKEEGDLLEPGDEEAAAALGGTFTRSRIGKGGKACHKIFSNHHHRLQLKAAPASSNPPGAPALPLHNSSVTANSQSPALLAGTNPVAVVADGGSCPAHYPVHECVFKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVGNFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGNIMEQNFEPIRRQSLTPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFKATIAMSQEFPLGIELLLNVLEVVAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRYDEFDGSIFTIPDDYKEDPSRFPDL", "length": 541, "molWeight": 60818, "crc64": "0215707FDFB92046", "md5": "DCC34E8B39A106F1C31963FA5D3B54A9"}}
{"primaryAccession": "Q8N7H5", "text": "This is RNA polymerase II-associated factor 1 homolog protein, from Human, contains 531 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N7H5", "organism_name": "Human", "protein_name": "RNA polymerase II-associated factor 1 homolog", "length": 531, "firstPublicDate": "2008-04-08", "FUNCTION": "Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency, PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1, PAF1C is required for transcription of Hox and Wnt target genes, PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL, PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3), PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription, PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors, In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription, Connects PAF1C with the RNF20/40 E3 ubiquitin-protein ligase complex, Involved in polyadenylation of mRNA precursors, Has oncogenic activity in vivo and in vitro", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the PAF1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQYKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKRSQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIEKTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEMMSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD", "length": 531, "molWeight": 59976, "crc64": "756F800AA64255D6", "md5": "84A895D9F0418B11F3BCE18ACDA866E1"}}
{"primaryAccession": "Q8N7J2", "text": "This is APC membrane recruitment protein 2 protein, from Human, contains 671 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N7J2", "organism_name": "Human", "protein_name": "APC membrane recruitment protein 2", "length": 671, "firstPublicDate": "2007-04-03", "FUNCTION": "Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning, Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Amer family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "METSRSRGGGGAVSERGGAGASVGVCRRKAEAGAGTGTLAADMDLHCDCAAETPAAEPPSGKINKAAFKLFKKRKSGGTMPSIFGVKNKGDGKSSGPTGLVRSRTHDGLAEVLVLESGRKEEPRGGGDSGGGGGGRPNPGPPRAAGPGGGSLASSSVAKSHSFFSLLKKNGRSENGKGEPVDASKAGGKQKRGLRGLFSGMRWHRKDKRAKAEAAEGRAPGGGLILPGSLTASLECVKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGARGEDAAGHRRAEPGPGEVRTAEDASRTGAVPVKTVPLVDSEGGSGRAPAAPDPASVDPPSDPSADRICLMFSDVTSLKSFDSLTGCGDIIADQEEEAGPSCDKHVPGPGKPALSKKNPGVVAYQGGGEEMASPDEVDDTYLQEFWDMLSQTEEQGPEPQEGAAKVAAALETKVVPETPKDTRCVEAAKDASSVKRRRLNRIPIEPHPKEEPKHPEKEQQEGVPNSDEGYWDSTTPGPEEDSSSSGKKAGIPRDSYSGDALYDLYADPDGSPATLPGGKDNEETSSLSRLKPVSPGTITCPLRTPGSLLKDSKIPISIKHLTNLPSSHPVVHQQPSRSEMPRTKIPVSKVLVRRVSNRGLAGTTIRATACHDSAKKL", "length": 671, "molWeight": 69507, "crc64": "0640CCCCD03E0334", "md5": "247E5F9BAE6E6398108841A926432208"}}
{"primaryAccession": "Q8N8N0", "text": "This is E3 ubiquitin-protein ligase RNF152 protein, from Human, contains 203 amino acids, has 1 RING-type Zinc finger, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [{"location": [12, 55], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8N8N0", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase RNF152", "length": 203, "firstPublicDate": "2004-01-16", "FUNCTION": "E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation, Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability (PubMed:25936802), Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation, Induces apoptosis when overexpressed (PubMed:21203937)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the RNF152 family", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKLPPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCRLLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLVFLLGIVLHNMSCISKRFTVISCG", "length": 203, "molWeight": 22357, "crc64": "0DFA570D00744BFA", "md5": "78B20A73C525FE171F635D464207FACF"}}
{"primaryAccession": "Q8N8Q8", "text": "This is Cytochrome c oxidase assembly protein COX18, mitochondrial protein, from Human, contains 333 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N8Q8", "organism_name": "Human", "protein_name": "Cytochrome c oxidase assembly protein COX18, mitochondrial", "length": 333, "firstPublicDate": "2003-11-14", "FUNCTION": "Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT-CO2/COX2) across the mitochondrial inner membrane, Plays a role in MT-CO2/COX2 maturation following the COX20-mediated stabilization of newly synthesized MT-CO2/COX2 protein and before the action of the metallochaperones SCO1/2, Essential for the assembly and stability of the mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the OXA1/ALB3/YidC family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLCRLGGRWLRPLPALQLWARDLPLAPVPTSGAKRPTLPVWAVAPVSAVHANGWYEALAASSPVRVAEEVLLGVHAATGLPWWGSILLSTVALRGAVTLPLAAYQHYILAKVENLQPEIKTIARHLNQEVAVRANQLGWSKRDARLTYLKNMRRLISELYVRDNCHPFKATVLVWIQLPMWIFMSFALRNLSTGAAHSEGFSVQEQLATGGILWFPDLTAPDSTWILPISVGVINLLIVEICALQKIGMSRFQTYITYFVRAMSVLMIPIAATVPSSIVLYWLCSSFVGLSQNLLLRSPGFRQLCRIPSTKSDSETPYKDIFAAFNTKFISRK", "length": 333, "molWeight": 37063, "crc64": "4F2C18C7E78C08EE", "md5": "C383425F8C03B1E809AB1BC17DC5DAAE"}}
{"primaryAccession": "Q8N983", "text": "This is Large ribosomal subunit protein mL43 protein, from Human, contains 215 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N983", "organism_name": "Human", "protein_name": "Large ribosomal subunit protein mL43", "length": 215, "firstPublicDate": "2004-07-19", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mL43 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTARGTPSRFLASVLHNGLGRYVQQLQRLSFSVSRDGASSRGAREFVEREVIDFARRNPGVVIYVNSRPCCVPRVVAEYLNGAVREESIHCKSVEEISTLVQKLADQSGLDVIRIRKPFHTDNPSIQGQWHPFTNKPTTFRGLRPREVQDPAPAQDTGLRLSAVAPQILLPGWPDPPDLPTVDPISSSLTSAPAPMLSAVSCLPIVPALTTVCSA", "length": 215, "molWeight": 23431, "crc64": "059C6E36FEB0D235", "md5": "2867960EF339BBBBC51C280C7CDA00DC"}}
{"primaryAccession": "Q8N9N8", "text": "This is Probable RNA-binding protein EIF1AD protein, from Human, contains 165 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N9N8", "organism_name": "Human", "protein_name": "Probable RNA-binding protein EIF1AD", "length": 165, "firstPublicDate": "2008-01-15", "FUNCTION": "Plays a role into cellular response to oxidative stress, Decreases cell proliferation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the EIF1AD family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSQATKRKHVVKEVLGEHIVPSDQQQIVRVLRTPGNNLHEVETAQGQRFLVSMPSKYRKNIWIKRGDFLIVDPIEEGEKVKAEISFVLCKDHVRSLQKEGFWPEAFSEVAEKHNNRNRQTQPELPAEPQLSGEESSSEDDSDLFVNTNRRQYHESEEESEEEEAA", "length": 165, "molWeight": 19053, "crc64": "33FB5ACB777084B2", "md5": "ACEA85581A64394C5E3723A7C0301A47"}}
{"primaryAccession": "Q8N9W6", "text": "This is Protein boule-like protein, from Human, contains 283 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N9W6", "organism_name": "Human", "protein_name": "Protein boule-like", "length": 283, "firstPublicDate": "2004-03-01", "FUNCTION": "Probable RNA-binding protein, which may be required during spermatogenesis, May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the RRM DAZ family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQTDSLSPSPNPVSPVPLNNPTSAPRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKGYGFVTFETQEDAQKILQEAEKLNYKDKKLNIGPAIRKQQVGIPRSSIMPAAGTMYLTTSTGYPYTYHNGVAYFHTPEVTSVPPPWPSRSVCSSPVMVAQPIYQQPAYHYQATTQYLPGQWQWSVPQPSASSAPFLYLQPSEVIYQPVEIAQDGGCVPPPLSLMETSVPEPYSDHGVQATYHQVYAPSAITMPAPVMQPEPIKTVWSIHY", "length": 283, "molWeight": 31301, "crc64": "7E28E99C116DAA16", "md5": "09966E4957842A44622400D7C79CC987"}}
{"primaryAccession": "Q8NAT1", "text": "This is Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 protein, from Human, contains 580 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8NAT1", "organism_name": "Human", "protein_name": "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "length": 580, "firstPublicDate": "2006-09-05", "FUNCTION": "O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein, Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyltransferase 61 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQILMEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLSTVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKITTWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLILNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGATVVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGLYPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILALQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT", "length": 580, "molWeight": 66615, "crc64": "57D7FD168373FD9D", "md5": "238CE5DB9BB9F51C6FBF8B7379C04DBE"}}
{"primaryAccession": "Q8NBI6", "text": "This is Xyloside xylosyltransferase 1 protein, from Human, contains 393 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8NBI6", "organism_name": "Human", "protein_name": "Xyloside xylosyltransferase 1", "length": 393, "firstPublicDate": "2006-05-16", "FUNCTION": "Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose (PubMed:22117070, PubMed:8982869), Known targets include Notch proteins and coagulation factors, such as F9 (PubMed:22117070, PubMed:8982869)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyltransferase 8 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGLLRGGLPCARAMARLGAVRSHYCALLLAAALAVCAFYYLGSGRETFSSATKRLKEARAGAPAAPSPPALELARGSVAPAPGAKAKSLEGGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDKLFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRHTFWQFRHENPQTRVGGPPPEGLPGFNSGVMLLNLEAMRQSPLYSRLLEPAQVQQLADKYHFRGHLGDQDFFTMIGMEHPKLFHVLDCTWNRQLCTWWRDHGYSDVFEAYFRCEGHVKIYHGNCNTPIPED", "length": 393, "molWeight": 43807, "crc64": "3C788AFDF933A23D", "md5": "D3EE2C84C7521A41E55DF34DD369D96B"}}
{"primaryAccession": "Q8NCE2", "text": "This is Myotubularin-related protein 14 protein, from Human, contains 650 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8NCE2", "organism_name": "Human", "protein_name": "Myotubularin-related protein 14", "length": 650, "firstPublicDate": "2006-11-28", "FUNCTION": "Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVERIEKRCLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRSKMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEEDCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYADFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQCWDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRKSHSSSPQSVLWNRPQPSEDRLPSQQGLAEARSSSSSSSNHSDNFFRMGSSPLEVPKPRSVDHPLPGSSLSTDYGSWQMVTGCGSIQERAVLHTDSSLPFSFPDELPNSCLLAALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL", "length": 650, "molWeight": 72203, "crc64": "C1B70E5140EF0716", "md5": "1C4C107534958B440062F26D3E7A42FA"}}
{"primaryAccession": "Q8NDT2", "text": "This is Putative RNA-binding protein 15B protein, from Human, contains 890 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8NDT2", "organism_name": "Human", "protein_name": "Putative RNA-binding protein 15B", "length": 890, "firstPublicDate": "2005-03-01", "FUNCTION": "RNA-binding protein that acts as a key regulator of N6-methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as alternative splicing of mRNAs and X chromosome inactivation mediated by Xist RNA (PubMed:16129689, PubMed:27602518), Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:27602518), Plays a key role in m6A methylation, possibly by binding target RNAs and recruiting the WMM complex (PubMed:27602518), Involved in random X inactivation mediated by Xist RNA: acts by binding Xist RNA and recruiting the WMM complex, which mediates m6A methylation, leading to target YTHDC1 reader on Xist RNA and promoting transcription repression activity of Xist (PubMed:27602518), Functions in the regulation of alternative or illicit splicing, possibly by regulating m6A methylation (PubMed:16129689), Inhibits pre-mRNA splicing (PubMed:21044963), Also functions as a mRNA export factor by acting as a cofactor for the nuclear export receptor NXF1 (PubMed:19586903)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RRM Spen family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGMSPRASPLPPPPPPPGAEPACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGLGTEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "length": 890, "molWeight": 97205, "crc64": "276C94252F036C83", "md5": "938137A1442D059E21072468763F7DED"}}
{"primaryAccession": "Q8NDX5", "text": "This is Polyhomeotic-like protein 3 protein, from Human, contains 983 amino acids, has 1 FCS-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [776, 810], "description": "FCS-type", "keyword_description": "Zinc finger", "textural_description": "FCS-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8NDX5", "organism_name": "Human", "protein_name": "Polyhomeotic-like protein 3", "length": 983, "firstPublicDate": "2005-12-20", "FUNCTION": "Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development, PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"FCS-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPDGAAREHILRQLPITYPSAEEDLASHEDSVPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARINSLKES", "length": 983, "molWeight": 106162, "crc64": "05819632A1675049", "md5": "1172A896C162BAD9071D97B6E031C7C2"}}
{"primaryAccession": "Q8NEW0", "text": "This is Zinc transporter 7 protein, from Human, contains 376 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8NEW0", "organism_name": "Human", "protein_name": "Zinc transporter 7", "length": 376, "firstPublicDate": "2008-01-15", "FUNCTION": "Zinc ion transporter mediating zinc entry from the cytosol into the lumen of organelles along the secretory pathway (PubMed:15525635, PubMed:15994300), By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases (PubMed:15525635, PubMed:15994300)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the cation diffusion facilitator (CDF) transporter (TC 2,A,4) family, SLC30A subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM", "length": 376, "molWeight": 41626, "crc64": "8E4230C4B9EC5848", "md5": "2B3FC4430E1179CDDB071A2EF1E4EE67"}}
{"primaryAccession": "Q8NF64", "text": "This is Zinc finger MIZ domain-containing protein 2 protein, from Human, contains 920 amino acids, has 1 SP-RING-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [585, 671], "description": "SP-RING-type", "keyword_description": "Zinc finger", "textural_description": "SP-RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8NF64", "organism_name": "Human", "protein_name": "Zinc finger MIZ domain-containing protein 2", "length": 920, "firstPublicDate": "2004-12-07", "FUNCTION": "Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"SP-RING-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNSMNPMKPALPPAPHGDGSFAYESVPWQQSATQPAGSLSVVTTVWGVGNATQSQVLGNPMGPAGSPSGSSMMPGVAGGSSALTSPQCLGQQAFAEGGANKGYVQQGVYSRGGYPGAPGFTTGYAGGPGGLGLPSHAARPSTDFTQAAAAAAVAAAAATATATATATVAALQEKQSQELSQYGAMGAGQSFNSQFLQHGGPRGPSVPAGMNPTGIGGVMGPSGLSPLAMNPTRAAGMTPLYAGQRLPQHGYPGPPQAQPLPRQGVKRTYSEVYPGQQYLQGGQYAPSTAQFAPSPGQPPAPSPSYPGHRLPLQQGMTQSLSVPGPTGLHYKPTEQFNGQGASFNGGSVSYSQPGLSGPTRSIPGYPSSPLPGNPTPPMTPSSSVPYMSPNQEVKSPFLPDLKPNLNSLHSSPSGSGPCDELRLTFPVRDGVVLEPFRLQHNLAVSNHVFQLRDSVYKTLIMRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLYLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSGTIPGTPGPNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMLGILIYIQNSDYEEITIDPTCSWKPVPVKPDMHIKEEPDGPALKRCRTVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSVPAPSDYPGQGSSFLGPGTFPESFPPTTPSTPTLAEFTPGPPPISYQSDIPSSLLTSEKSTACLPSQMAPAGHLDPTHNPGTPGLHTSNLGAPPGPQLHHSNPPPASRQSLGQASLGPTGELAFSPATGVMGPPSMSGAGEAPEPALDLLPELTNPDELLSYLGPPDLPTNNNDDLLSLFENN", "length": 920, "molWeight": 96537, "crc64": "C9CE99D0B0798B9F", "md5": "F7A417DC823C99B57068C20329E9739B"}}
{"primaryAccession": "Q8NFJ6", "text": "This is Prokineticin receptor 2 protein, from Human, contains 384 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8NFJ6", "organism_name": "Human", "protein_name": "Prokineticin receptor 2", "length": 384, "firstPublicDate": "2003-07-19", "FUNCTION": "Receptor for prokineticin 2, Exclusively coupled to the G(q) subclass of heteromeric G proteins, Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIALAGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSILIAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSKSSADLDLRTNGVPTTEEVDCIRLK", "length": 384, "molWeight": 43996, "crc64": "2D5BFA3655347B5E", "md5": "E0711360561C1EE2633D2FAAAB7163FE"}}
{"primaryAccession": "Q8NFW8", "text": "This is N-acylneuraminate cytidylyltransferase protein, from Human, contains 434 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8NFW8", "organism_name": "Human", "protein_name": "N-acylneuraminate cytidylyltransferase", "length": 434, "firstPublicDate": "2005-02-01", "FUNCTION": "Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid, Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CMP-NeuNAc synthase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDSVEKGAATSVSNPRGRPSRGRPPKLQRNSRGGQGRGVEKPPHLAALILARGGSKGIPLKNIKHLAGVPLIGWVLRAALDSGAFQSVWVSTDHDEIENVAKQFGAQVHRRSSEVSKDSSTSLDAIIEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHQFRWSEIQKGVREVTEPLNLNPAKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEMRAEHSVDIDVDIDWPIAEQRVLRYGYFGKEKLKEIKLLVCNIDGCLTNGHIYVSGDQKEIISYDVKDAIGISLLKKSGIEVRLISERACSKQTLSSLKLDCKMEVSVSDKLAVVDEWRKEMGLCWKEVAYLGNEVSDEECLKRVGLSGAPADACSTAQKAVGYICKCNGGRGAIREFAEHICLLMEKVNNSCQK", "length": 434, "molWeight": 48379, "crc64": "B303B6647EF81A3A", "md5": "2EE58F4E0D5DCED3969994E4CD8C44C7"}}
{"primaryAccession": "Q8NHJ6", "text": "This is Leukocyte immunoglobulin-like receptor subfamily B member 4 protein, from Human, contains 448 amino acids, has 2 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [27, 118], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}, {"location": [124, 218], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "Q8NHJ6", "organism_name": "Human", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 4", "length": 448, "firstPublicDate": "2003-10-03", "FUNCTION": "Inhibitory receptor involved in the down-regulation of the immune response and the development of immune tolerance (PubMed:11875462), Receptor for FN1 (PubMed:34089617), Receptor for apolipoprotein APOE (PubMed:30333625), Receptor for ALCAM/CD166 (PubMed:29263213), Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (PubMed:9151699), Inhibits FCGR1A/CD64-mediated monocyte activation by inducing phosphatase-mediated down-regulation of the phosphorylation of multiple proteins including LCK, SYK, LAT and ERK, leading to a reduction in TNF production (PubMed:19833736), This inhibition of monocyte activation occurs at least in part via binding to FN1 (PubMed:34089617), Inhibits T cell proliferation, inducing anergy, suppressing the differentiation of IFNG-producing CD8+ cytoxic T cells and enhancing the generation of CD8+ T suppressor cells (PubMed:16493035, PubMed:19833736, PubMed:29263213), Induces up-regulation of CD86 on dendritic cells (PubMed:19860908), Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation (PubMed:11875462)", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {"Ig-like C2-type Immunoglobulin domain": 2}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MIPTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLMPTGSVPHSGLRRHWEVLIGVLVVSILLLSLLLFLLLQHWRQGKHRTLAQRQADFQRPPGAAEPEPKDGGLQRRSSPAADVQGENFCAAVKNTQPEDGVEMDTRQSPHDEDPQAVTYAKVKHSRPRREMASPPSPLSGEFLDTKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSFTLRQKATEPPPSQEGASPAEPSVYATLAIH", "length": 448, "molWeight": 49356, "crc64": "C18C21694F283FBB", "md5": "BA1289D70B1A20201BA27FDF704C8944"}}
{"primaryAccession": "Q8NHS3", "text": "This is Major facilitator superfamily domain-containing protein 8 protein, from Human, contains 518 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8NHS3", "organism_name": "Human", "protein_name": "Major facilitator superfamily domain-containing protein 8", "length": 518, "firstPublicDate": "2007-11-13", "FUNCTION": "May be a carrier that transport small solutes by using chemiosmotic ion gradients", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the major facilitator superfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAGLRNESEQEPLLGDTPGSREWDILETEEHYKSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKIDPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPRKEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSAFLGILNIILILAILREHRVDDSGRQCKSINFEEASTDEAQVPQGNIDQVAVVAINVLFFVTLFIFALFETIITPLTMDMYAWTQEQAVLYNGIILAALGVEAVVIFLGVKLLSKKIGERAILLGGLIVVWVGFFILLPWGNQFPKIQWEDLHNNSIPNTTFGEIIIGLWKSPMEDDNERPTGCSIEQAWCLYTPVIHLAQFLTSAVLIGLGYPVCNLMSYTLYSKILGPKPQGVYMGWLTASGSGARILGPMFISQVYAHWGPRWAFSLVCGIIVLTITLLGVVYKRLIALSVRYGRIQE", "length": 518, "molWeight": 57628, "crc64": "105A5F6A35B2291F", "md5": "323DCD012BCB0D835DD36AAA03BC13D4"}}
{"primaryAccession": "Q8R0W1", "text": "This is CLOCK-interacting pacemaker protein, from Mouse, contains 432 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8R0W1", "organism_name": "Mouse", "protein_name": "CLOCK-interacting pacemaker", "length": 432, "firstPublicDate": "2006-10-31", "FUNCTION": "Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-BMAL1 transcriptional activity in the circadian-clock mechanism, May stimulate BMAL1-dependent phosphorylation of CLOCK (PubMed:17310242, PubMed:19414601), However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock (PubMed:25862660)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRLLTRRAGHGAATLALRVIHMQRVPVLRLPAILDMERKIPSRESPRRLSAKPGRGTEMKKLARPLGVVAADSDKDSGFSDGSSECLSSAEQMESEDMLSALGCKREDKRRQPSKAADTALPTLPPMVVMKSVLVKQGSSSSQLQSWTVQPSFEVISAQPQLFVLHPPVPSPVSSCQTGEKKSESRNYLPILNSYTKIAPHPGKRGLNSEDRGTSGVSKKLCTERPGPSLSSSEPAKTGRVLSSPSTPAPPSSKLTEDSTLQGVPSLGAGGSPQTLQPVSSSHVAKAPSLTLASPASPVCASDSTLHGLESSSPLSPLSASYTSPLWAAEHLCRSPDIFSEQRQNKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQAELDQLKEQTQMFIEATKSRAPQAWAKLQASLTSGSSHSGSDLDTLSDHPDV", "length": 432, "molWeight": 46320, "crc64": "E304D1F0D8D70D9A", "md5": "ADA75E5010DE3C07759D0B851D7DA4E4"}}
{"primaryAccession": "Q8R2Y0", "text": "This is Monoacylglycerol lipase ABHD6 protein, from Mouse, contains 336 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8R2Y0", "organism_name": "Mouse", "protein_name": "Monoacylglycerol lipase ABHD6", "length": 336, "firstPublicDate": "2007-03-20", "FUNCTION": "Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol (PubMed:18096503, PubMed:20657592), Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways (PubMed:18096503, PubMed:20657592), Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (PubMed:24095738), Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism (PubMed:26491015), BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting (PubMed:26491015)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the AB hydrolase superfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYAHHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGHVAGVYAAYYPSDVCSLSLVCPAGLQYSTDNPFVQRLKELEESAAIQKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNSFYRKLFLEIVNEKSRYSLHENMDKIKVPTQIIWGKQDQVLDVSGADILAKSISNSQVEVLENCGHSVVMERPRKTAKLIVDFLASVHNTDNKKLN", "length": 336, "molWeight": 38205, "crc64": "4C207C66DBE41FE4", "md5": "2637572A5B2E42FF26B2B34D8D17E25E"}}
{"primaryAccession": "Q8R2Z5", "text": "This is von Willebrand factor A domain-containing protein 1 protein, from Mouse, contains 415 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8R2Z5", "organism_name": "Mouse", "protein_name": "von Willebrand factor A domain-containing protein 1", "length": 415, "firstPublicDate": "2007-10-23", "FUNCTION": "Promotes matrix assembly (PubMed:18757743), Involved in the organization of skeletal muscles and in the formation of neuromuscular junctions (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLFWTAFSMALSLRLALARSSIERGSTASDPQGDLLFLLDSSASVSHYEFSRVREFVGQLVATMSFGPGALRASLVHVGSQPHTEFTFDQYSSGQAIQDAIRVAPQRMGDTNTGLALAYAKEQLFAEEAGARPGVPKVLVWVTDGGSSDPVGPPMQELKDLGVTIFIVSTGRGNLLELLAAASAPAEKHLHFVDVDDLPIIARELRGSITDAMQPQQLHASEVLSSGFRLSWPPLLTADSGYYVLELVPSGKLATTRRQQLPGNATSWTWTDLDPDTDYEVSLLPESNVHLLRPQHVRVRTLQEEAGPERIVISHARPRSLRVSWAPALGPDSALGYHVQLGPLQGGSLERVEVPAGQNSTTVQGLTPCTTYLVTVTAAFRSGRQRALSAKACTASGARTRAPQSMRPEAGPREP", "length": 415, "molWeight": 44709, "crc64": "C3887963B2E334FE", "md5": "49488F86FFEDDF747A1C32EE2952EB26"}}
{"primaryAccession": "Q8R366", "text": "This is Immunoglobulin superfamily member 8 protein, from Mouse, contains 611 amino acids, has 4 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [26, 143], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}, {"location": [160, 284], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}, {"location": [301, 422], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}, {"location": [429, 554], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "Q8R366", "organism_name": "Mouse", "protein_name": "Immunoglobulin superfamily member 8", "length": 611, "firstPublicDate": "2006-03-07", "FUNCTION": "May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function, May regulate proliferation and differentiation of keratinocytes, May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers, May also play a role on integrin-dependent morphology and motility functions, May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {"Ig-like C2-type Immunoglobulin domain": 4}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGVPSPTPLSSLLLLLLILGTRCYARQVHVPRGPLYRVAGTAVSISCNVSDYEGPAQQDFEWFMYRPEAPATSLGIVSTKDSQFSYAVFGPRVASGDLQVQRLKGDSVVLKIARLQAQDSGFYECYTPSTDTQYLGNYSAKVELRVLPDELQVSAAPPGPRGRQAATSPSRLTVHEGQELALGCLAQTKTKKHTHLSVSFGRAIPEAPVGRATLQEVVGLRSDMAVEAGAPYAERLASGELRLSKEGTDRYRMVVGGAQAGDSGTYHCTAAEWIQDPDGSWVQVAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPPGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGIGSLGPGYEDRHIAMEKVASRTYRLRLEAARPADAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVRGGPPGLRLAASWWVERPEEGELSSGPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSHRLRLHGLGPEDEGIYHCAPSAWVQHADYSWYQAGSARSGPVTVYPYTHAVDTLFVPLLVGTGVALVTGASVLATITCCFMKRMRKR", "length": 611, "molWeight": 65011, "crc64": "B5581BE0DF01565A", "md5": "AB541E8F6A481EF68EFD7366BF634102"}}
{"primaryAccession": "Q8R3H7", "text": "This is Heparan sulfate 2-O-sulfotransferase 1 protein, from Mouse, contains 356 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8R3H7", "organism_name": "Mouse", "protein_name": "Heparan sulfate 2-O-sulfotransferase 1", "length": 356, "firstPublicDate": "2005-06-07", "FUNCTION": "Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS), 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes, Required for metanephric development of kidney formation, suggesting that 2-O-sulfation within HS is essential for signaling between ureteric bud and metanephric mesenchyme, Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the sulfotransferase 3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRAKLERAIARHEVREIEQRHTMDGPRQDATLDEEEDIIIIYNRVPKTASTSFTNIAYDLCAKNRYHVLHINTTKNNPVMSLQDQVRFVKNITTWNEMKPGFYHGHISYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKSNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATDLYRTGKKSHLRKTTEKKLPTKQTIAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEKIYPKSN", "length": 356, "molWeight": 41813, "crc64": "E83D315141E57475", "md5": "5649073611AEA002B23190D44AA07009"}}
{"primaryAccession": "Q8R507", "text": "This is Ribitol-5-phosphate transferase FKTN protein, from Mouse, contains 461 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8R507", "organism_name": "Mouse", "protein_name": "Ribitol-5-phosphate transferase FKTN", "length": 461, "firstPublicDate": "2004-04-13", "FUNCTION": "Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:12471058), This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-beta-1 (By similarity), Required for normal location of POMGNT1 in Golgi membranes, and for normal POMGNT1 activity (PubMed:19017726), May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes (PubMed:19017726, PubMed:22922256), Could be involved in brain development (Probable)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the LicD transferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSRINKNVVLALLTLTSSAFLLFQLYYYKHYLSARNGPGSSKSKGNRVGFDSTQWRAVKKFIMLTSSQNVPVFLIDPWILESINKNFEQVKNASQGPASECRFFCVPRDFTAFALQYHLWKNEDGWFRIAENMGFQCLKTESKDPRLDGIDSLSGTEIPLHYVCKLTTHAIHLVVFHERSGNYLWHGHLRLKGHMDRKFVPFRKLQFGRYPGAFDRPELQQVTVDGLDMLIPKDPGRFLEEVPHSRFIECRYKEARAFLQQYIDDNTVDAMVFRKRAKELLQLAAKTLKDLGVPFWLSSGTCLGWYRQCGIIPYSKDVDLGIFIQDYKPDIILAFQEAGLPLKHKFGKVEDSLELSFQGKNDVKLDIFFFYEEADHLWNGGTQARTGKKFKYLFPKFTLCWTEFVDIKVHVPCETVDYIEANYGKTWKIPIKTWDWKSSPPNVQPNGIWPISEWDEVIQLY", "length": 461, "molWeight": 53579, "crc64": "1E1E0C5F187FCC39", "md5": "C514B8C14CD093CDB4EE3A00584CA25D"}}
{"primaryAccession": "Q8RWV0", "text": "This is Transketolase-1, chloroplastic protein, from Mouse-ear cress, contains 741 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8RWV0", "organism_name": "Mouse-ear cress", "protein_name": "Transketolase-1, chloroplastic", "length": 741, "firstPublicDate": "2013-03-06", "FUNCTION": "Catalyzes the reversible transfer of a two-carbon ketol group from fructose-6-phosphate or sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to yield xylulose-5-phosphate and erythrose-4-phosphate or ribose-5-phosphate, respectively (By similarity), Could act as a stress sensor involved in adaptation process", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the transketolase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASTSSLALSQALLARAISHHGSDQRGSLPAFSGLKSTGSRASASSRRRIAQSMTKNRSLRPLVRAAAVETVEPTTDSSIVDKSVNSIRFLAIDAVEKAKSGHPGLPMGCAPMAHILYDEVMRYNPKNPYWFNRDRFVLSAGHGCMLLYALLHLAGYDSVQEEDLKQFRQWGSKTPGHPENFETPGIEVTTGPLGQGIANAVGLALAEKHLAARFNKPDAEVVDHYTYAILGDGCQMEGISNEACSLAGHWGLGKLIAFYDDNHISIDGDTEIAFTENVDQRFEALGWHVIWVKNGNTGYDEIRAAIKEAKTVTDKPTLIKVTTTIGYGSPNKANSYSVHGAALGEKEVEATRNNLGWPYEPFQVPDDVKSHWSRHTPEGATLESDWSAKFAAYEKKYPEEASELKSIITGELPAGWEKALPTYTPESPGDATRNLSQQCLNALAKVVPGFLGGSADLASSNMTLLKAFGDFQKATPEERNLRFGVREHGMGAICNGIALHSPGLIPYCATFFVFTDYMRGAMRISALSEAGVIYVMTHDSIGLGEDGPTHQPIEHIASFRAMPNTLMFRPADGNETAGAYKIAVTKRKTPSILALSRQKLPHLPGTSIEGVEKGGYTISDDSSGNKPDVILIGTGSELEIAAQAAEVLRKDGKTVRVVSFVCWELFDEQSDEYKESVLPSDVSARVSIEAASTFGWGKIVGGKGKSIGINSFGASAPAPLLYKEFGITVEAVVDAAKSFF", "length": 741, "molWeight": 79968, "crc64": "5886543FBA70E79C", "md5": "770DB7F449C52A1EF57EB76DD5B33871"}}
{"primaryAccession": "Q8RWV3", "text": "This is Cyclin-L1-1 protein, from Mouse-ear cress, contains 416 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8RWV3", "organism_name": "Mouse-ear cress", "protein_name": "Cyclin-L1-1", "length": 416, "firstPublicDate": "2007-05-15", "FUNCTION": "Cognate cyclin for CDKG1, Required for synapsis and male meiosis, and for the proper splicing of specific resistance (R) genes, Involved in regulation of DNA methylation and transcriptional silencing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the cyclin family, Cyclin L subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIYTAIDNFYLSDEQLKASPSRKDGIDETTEISLRIYGCDLIQEGGILLKLPQAVMATGQVLFQRFYCKKSLAKFDVKIVAASCVWLASKLEENPKKARQVIIVFHRMECRRENLPLEHLDMYAKKFSELKVELSRTERHILKEMGFVCHVEHPHKFISNYLATLETPPELRQEAWNLANDSLRTTLCVRFRSEVVACGVVYAAARRFQVPLPENPPWWKAFDADKSSIDEVCRVLAHLYSLPKAQYISVCKDGKPFTFSSRSGNSQGQSATKDLLPGAGEAVDTKCTAGSANNDLKDGMVTTPHEKATDSKKSGTESNSQPIVGDSSYERSKVGDRERESDREKERGRERDRGRSHRGRDSDRDSDRERDKLKDRSHHRSRDRLKDSGGHSDKSRHHSSRDRDYRDSSKDRRRHH", "length": 416, "molWeight": 47555, "crc64": "098209EA635598C5", "md5": "FD79FFFCDFD4BD525B49E78D02BB6B19"}}
{"primaryAccession": "Q8RX88", "text": "This is CAAX prenyl protease 1 homolog protein, from Mouse-ear cress, contains 424 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8RX88", "organism_name": "Mouse-ear cress", "protein_name": "CAAX prenyl protease 1 homolog", "length": 424, "firstPublicDate": "2008-12-16", "FUNCTION": "Proteolytically removes the C-terminal three residues of farnesylated proteins, The substrate specificity is only partially overlapping with that of FACE2", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the peptidase M48A family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAIPFMETVVGFMIVMYIFETYLDLRQLTALKLPTLPKTLVGVISQEKFEKSRAYSLDKSYFHFVHEFVTILMDSAILFFGILPWFWKMSGAVLPRLGLDPENEILHTLSFLAGVMTWSQITDLPFSLYSTFVIESRHGFNKQTIWMFIRDMIKGTFLSVILGPPIVAAIIFIVQKGGPYLAIYLWAFMFILSLVMMTIYPVLIAPLFNKFTPLPDGDLREKIEKLASSLKFPLKKLFVVDGSTRSSHSNAYMYGFFKNKRIVLYDTLIQQCKNEDEIVAVIAHELGHWKLNHTTYSFIAVQILAFLQFGGYTLVRNSTDLFRSFGFDTQPVLIGLIIFQHTVIPLQHLVSFGLNLVSRAFEFQADAFAVKLGYAKDLRPALVKLQEENLSAMNTDPLYSAYHYSHPPLVERLRAIDGEDKKTD", "length": 424, "molWeight": 48482, "crc64": "B894AE17C8044857", "md5": "95F22494A72344FCCDD3A45A75F9248C"}}
{"primaryAccession": "Q8RXN0", "text": "This is ABC transporter G family member 11 protein, from Mouse-ear cress, contains 703 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8RXN0", "organism_name": "Mouse-ear cress", "protein_name": "ABC transporter G family member 11", "length": 703, "firstPublicDate": "2006-06-27", "FUNCTION": "Required for the cuticle, root suberin and pollen coat development by controlling cutin and maybe wax transport to the extracellular matrix (PubMed:24112720, PubMed:20035035), Involved in developmental plasticity and stress responses, Together with ABCG9 and ABCG14, required for vascular development by regulating lipid/sterol homeostasis (PubMed:24112720), May be a transporter of lignin precursors during tracheary element differentiation (PubMed:28921082)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the ABC transporter superfamily, ABCG family, Eye pigment precursor importer (TC 3,A,1,204) subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEIEASRQQTTVPVSVGGGNFPVGGLSPLSEAIWREKAPTEFVGDVSARLTWQDLTVMVTMGDGETQNVLEGLTGYAEPGSLTALMGPSGSGKSTMLDALASRLAANAFLSGTVLLNGRKTKLSFGTAAYVTQDDNLIGTLTVRETIWYSARVRLPDKMLRSEKRALVERTIIEMGLQDCADTVIGNWHLRGISGGEKRRVSIALEILMRPRLLFLDEPTSGLDSASAFFVTQTLRALSRDGRTVIASIHQPSSEVFELFDRLYLLSGGKTVYFGQASDAYEFFAQAGFPCPALRNPSDHFLRCINSDFDKVRATLKGSMKLRFEASDDPLEKITTAEAIRLLVDYYHTSDYYYTAKAKVEEISQFKGTILDSGGSQASFLLQTYTLTKRSFINMSRDFGYYWLRLLIYILVTVCIGTIYLNVGTSYSAILARGSCASFVFGFVTFMSIGGFPSFVEDMKVFQRERLNGHYGVAAFVIANTLSATPFLIMITFISGTICYFMVGLHPGFTHYLFFVLCLYASVTVVESLMMAIASIVPNFLMGIIIGAGIQGIFMLVSGFFRLPNDIPKPFWRYPMSYISFHFWALQGQYQNDLRGLTFDSQGSAFKIPGEYVLENVFQIDLHRSKWINLSVILSMIIIYRIIFFIMIKTNEDVTPWVRGYIARRRMKQKNGTQNTTVAPDGLTQSPSLRNYIATRTDGARRW", "length": 703, "molWeight": 78413, "crc64": "8D85EE940AC39003", "md5": "4DFCB6C14F77BD2C62DC02CD78308880"}}
{"primaryAccession": "Q8S1D9", "text": "This is Phospholipase A1 EG1, chloroplastic/mitochondrial protein, from Rice, contains 435 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8S1D9", "organism_name": "Rice", "protein_name": "Phospholipase A1 EG1, chloroplastic/mitochondrial", "length": 435, "firstPublicDate": "2015-12-09", "FUNCTION": "Phospholipase that releases free fatty acids from phospholipids, Catalyzes the initial step of jasmonate (JA) biosynthesis, Required for the biosynthesis of endogenous JA in seedling, inflorescence and spikelets, Not essential for JA biosynthesis after wounding (PubMed:24647160), Mediates spikelet development and specification of empty-glume identity (PubMed:18980657, PubMed:24647160), Functions in a high temperature-dependent manner to maintain floral developmental robustness under heat stress conditions, Functions by safeguarding the expression of several floral identity genes, such as MADS1, MADS6 and G1 (PubMed:27367609)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTLPRQCAAACRTGGGGGGVVRCRAVAAAGGAVAVRDAVVAPVARRGAARKTAETVAGMWREVQGCGDWEGMLEPAPHPVLRGEVARYGELVGACYKAFDLDPASRRYLNCKYGRERMLEEVGMGGAGYEVTRYIYAAADVSVPTMEPSTSGRGRWIGYVAVSTDEMSRRLGRRDVLVSFRGTVTPAEWMANLMSSLEAARLDPCDPRPDVKVESGFLSLYTSADKTCRFGGAGSCREQLLREVSRLVAAYSGGGEDVSVTLAGHSMGSALALLSAYDLAELGLNRAAPVTVFSFGGPRVGNAAFKARCDELGVKALRVTNVHDPITKLPGVFLNEATAGVLRPWRHSCYTHVGVELPLDFFKVGDLASVHDLATYISLLRGADKKQPAAAAADAGGVLAKVMDFVGRRRGGGALPWHDAAMIQMGGLVQTLGLI", "length": 435, "molWeight": 46011, "crc64": "658FB5E4F3F2BC9B", "md5": "07E72C87AE15021AD669C07D50400072"}}
{"primaryAccession": "Q8S4F6", "text": "This is Sulfoquinovosyl transferase SQD2 protein, from Mouse-ear cress, contains 510 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8S4F6", "organism_name": "Mouse-ear cress", "protein_name": "Sulfoquinovosyl transferase SQD2", "length": 510, "firstPublicDate": "2015-04-01", "FUNCTION": "Catalyzes the transfer of the sulfoquinovose moiety from UDP-sulfoquinovose to diacylglycerol during sulfolipid biosynthesis (PubMed:11960029), Sulfolipid contributes to maintaining a negatively charged lipid-water interface, a requirement for proper function of photosynthetic membranes (PubMed:11960029), Sulfolipid may also function as a substitute of anionic phospholipids under phosphate-limited growth conditions (PubMed:11960029)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the glycosyltransferase group 1 family, Glycosyltransferase 4 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTTLSSINLSIPPHLLPSTTNTCSSSSATSCSPPRSSSFVLHSPLSFGHRRLPISKKSKLRFCGVITKEAVSGSNDMTITQVREDDESEIDAPLLDPESLSKPRRIALFVEPSPFAYVSGYKNRFQNFIRYLREMGDEVIVVTTHEGVPEEFYGARVIGSRSFPCPYYQKVPLSLALSPRIISEIARFKPDIIHASSPGVMVFGALAIAKMLSVPIVMSYHTHVPVYIPRYTFSWLVKPMWSIIRFLHRAADLTLVPSAAIGKDLIAAGATAANQLRLWNKGVDSESFNPRFRSQEMRIRLSNGEPEKPLVIHVGRIGVEKSLELLKSVMDKLPEARIAFIGDGPYKEDLEKLFTGMPAVFTGTLQGDELSQAYASGDVFVMPSESETLGLVVLEAMSSGLPVVAARAGGIPDIIPEDQEGKTGFLFNPGDVEDCVTKLRTLLHDRETREIIGKAAREETEKYDWRAATTKIRNEQYSAAIWFWRKKKVHVLGPINWLIKRLFPVPEGNV", "length": 510, "molWeight": 56630, "crc64": "20E57D318D6BED68", "md5": "B9E16E9DC3DBDBB6BF09702924180B1D"}}
{"primaryAccession": "Q8S8P5", "text": "This is Probable WRKY transcription factor 33 protein, from Mouse-ear cress, contains 519 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8S8P5", "organism_name": "Mouse-ear cress", "protein_name": "Probable WRKY transcription factor 33", "length": 519, "firstPublicDate": "2003-04-11", "FUNCTION": "Transcription factor, Interacts specifically with the W box (5'-TTGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element, Involved in defense responses, Required for resistance to the necrotrophic fungal pathogen B,cinerea (PubMed:17059405, PubMed:21990940), Regulates the antagonistic relationship between defense pathways mediating responses to the bacterial pathogen P, syringae and the necrotrophic pathogen B,cinerea (PubMed:17059405), Required for the phytoalexin camalexin synthesis following infection with B,cinerea, Acts as positive regulator of the camalexin biosynthetic genes PAD3 (CYP71B15) and CYP71A13 by binding to their promoters (PubMed:21498677, PubMed:22392279), Acts downstream of MPK3 and MPK6 in reprogramming the expression of camalexin biosynthetic genes, which drives the metabolic flow to camalexin production (PubMed:21498677), Functions with WRKY25 as positive regulator of salt stress response and abscisic acid (ABA) signaling (PubMed:18839316), Functions with WRKY25 and WRKY26 as positive regulator of plant thermotolerance by partially participating in ethylene-response signal transduction pathway (PubMed:21336597), The DNA-binding activity of WRKY33 is increased by SIB1 and SIB2 (PubMed:21990940)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WRKY group I family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAASFLTMDNSRTRQNMNGSANWSQQSGRTSTSSLEDLEIPKFRSFAPSSISISPSLVSPSTCFSPSLFLDSPAFVSSSANVLASPTTGALITNVTNQKGINEGDKSNNNNFNLFDFSFHTQSSGVSAPTTTTTTTTTTTTTNSSIFQSQEQQKKNQSEQWSQTETRPNNQAVSYNGREQRKGEDGYNWRKYGQKQVKGSENPRSYYKCTFPNCPTKKKVERSLEGQITEIVYKGSHNHPKPQSTRRSSSSSSTFHSAVYNASLDHNRQASSDQPNSNNSFHQSDSFGMQQEDNTTSDSVGDDEFEQGSSIVSRDEEDCGSEPEAKRWKGDNETNGGNGGGSKTVREPRIVVQTTSDIDILDDGYRWRKYGQKVVKGNPNPRSYYKCTTIGCPVRKHVERASHDMRAVITTYEGKHNHDVPAARGSGYATNRAPQDSSSVPIRPAAIAGHSNYTTSSQAPYTLQMLHNNNTNTGPFGYAMNNNNNNSNLQTQQNFVGGGFSRAKEEPNEETSFFDSFMP", "length": 519, "molWeight": 57179, "crc64": "A90A6A8A2DF56DB1", "md5": "24C4CA59DBDC5A9232DEA3768C33EE37"}}
{"primaryAccession": "Q8T6B9", "text": "This is Poly(U)-binding-splicing factor half pint protein, from Fruit fly, contains 637 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8T6B9", "organism_name": "Fruit fly", "protein_name": "Poly(U)-binding-splicing factor half pint", "length": 637, "firstPublicDate": "2004-02-02", "FUNCTION": "Splicing factor that regulates oogenesis and controls both mitosis and mRNA localization in the germline by regulating mRNA splicing of a subset of genes within the ovary, Probably acts by regulating the alternative splice site selection of the otu transcript, Also regulates the alternative splicing of eIF4E1 and grk, while it is not involved in the splicing of par-1, sqd and psq", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RRM half pint family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGSNDRASRSPRSDDQREISDMPATKRTRSDSGKSTDSKIPYLSQPLYDLKQTGDVKFGPGTRSALLGLLGGALPKLSSEQHDLVSKAKKYAMEQSIKMVLMKQTLAHQQQQLATQRTQVQRQQALALMCRVYVGSISFELKEDTIRVAFTPFGPIKSINMSWDPITQKHKGFAFVEYEIPEGAQLALEQMNGALMGGRNIKVGRPSNMPQAQQVIDEVQEEAKSFNRIYVASIHPDLSEEDIKSVFEAFGPILYCKLAQGTSLHTHKGYGFIEYANKQAMDEAIASMNLFDLGGQLLRVGRSITPPNALACPTTNSTMPTAAAVAAAAATAKIQALDAVASNAVLGLSQNTPVMAAGAVVTKVGAMPVVSAATSAAALHPALAQAAPALLPPGIFQAPTPVAPSLLGVPAGLQPLQAVVPTLPPPALLATPTLPMTVGGVGVGLVPTVATLAGAEASKGAAAAAALSAAANNAAVTAANLSENIKKAHEKQQEELQKKLMDEGDVQTLQQQENMSIKGQSARQLVMQRLMRPVDSRVIILRNMVGPEDVDETLQEEIQEECSKFGTVSRVIIFNEKQTENEDDDEAEIIVKIFVEFSAGAEAMRGKEALDGRFFGGRRVVAELYDQGIFDQGDLSG", "length": 637, "molWeight": 67940, "crc64": "F0AD184D9EEF145F", "md5": "85F3626BEA15F95DAC29EA00B3F6F147"}}
{"primaryAccession": "Q8TAD4", "text": "This is Proton-coupled zinc antiporter SLC30A5 protein, from Human, contains 765 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8TAD4", "organism_name": "Human", "protein_name": "Proton-coupled zinc antiporter SLC30A5", "length": 765, "firstPublicDate": "2008-01-15", "FUNCTION": "Zinc ion:proton antiporter mediating influx and efflux of zinc at the plasma membrane", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the cation diffusion facilitator (CDF) transporter (TC 2,A,4) family, SLC30A subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEEKYGGDVLAGPGGGGGLGPVDVPSARLTKYIVLLCFTKFLKAVGLFESYDLLKAVHIVQFIFILKLGTAFFMVLFQKPFSSGKTITKHQWIKIFKHAVAGCIISLLWFFGLTLCGPLRTLLLFEHSDIVVISLLSVLFTSSGGGPAKTRGAAFFIIAVICLLLFDNDDLMAKMAEHPEGHHDSALTHMLYTAIAFLGVADHKGGVLLLVLALCCKVGFHTASRKLSVDVGGAKRLQALSHLVSVLLLCPWVIVLSVTTESKVESWFSLIMPFATVIFFVMILDFYVDSICSVKMEVSKCARYGSFPIFISALLFGNFWTHPITDQLRAMNKAAHQESTEHVLSGGVVVSAIFFILSANILSSPSKRGQKGTLIGYSPEGTPLYNFMGDAFQHSSQSIPRFIKESLKQILEESDSRQIFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIFSYGYGRIEILSGFINGLFLIVIAFFVFMESVARLIDPPELDTHMLTPVSVGGLIVNLIGICAFSHAHSHAHGASQGSCHSSDHSHSHHMHGHSDHGHGHSHGSAGGGMNANMRGVFLHVLADTLGSIGVIVSTVLIEQFGWFIADPLCSLFIAILIFLSVVPLIKDACQVLLLRLPPEYEKELHIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQVTSDVLEQRIVQQVTGILKDAGVNNLTIQVEKEAYFQHMSGLSTGFHDVLAMTKQMESMKYCKDGTYIM", "length": 765, "molWeight": 84047, "crc64": "CD96BB6D710DF42D", "md5": "A6534B6D741F1839F070BF0D49BE272F"}}
{"primaryAccession": "Q8TAT5", "text": "This is Endonuclease 8-like 3 protein, from Human, contains 605 amino acids, has 1 FPG-type Zinc finger, has 1 RanBP2-type Zinc finger, has 2 GRF-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [247, 281], "description": "FPG-type", "keyword_description": "Zinc finger", "textural_description": "FPG-type Zinc finger"}, {"location": [317, 346], "description": "RanBP2-type", "keyword_description": "Zinc finger", "textural_description": "RanBP2-type Zinc finger"}, {"location": [507, 550], "description": "GRF-type", "keyword_description": "Zinc finger", "textural_description": "GRF-type Zinc finger"}, {"location": [554, 596], "description": "GRF-type", "keyword_description": "Zinc finger", "textural_description": "GRF-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8TAT5", "organism_name": "Human", "protein_name": "Endonuclease 8-like 3", "length": 605, "firstPublicDate": "2004-12-07", "FUNCTION": "DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA) (PubMed:12433996, PubMed:19170771, PubMed:22569481, PubMed:23755964), Mediates interstrand cross-link repair in response to replication stress: acts by mediating DNA glycosylase activity, cleaving one of the two N-glycosyl bonds comprising the interstrand cross-link, which avoids the formation of a double-strand break but generates an abasic site that is bypassed by translesion synthesis polymerases (By similarity), In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA (PubMed:12433996, PubMed:19170771, PubMed:22569481, PubMed:23755964), No activity on 8-oxoG detected (PubMed:12433996, PubMed:19170771, PubMed:22569481, PubMed:23755964), Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity (PubMed:12433996, PubMed:19170771, PubMed:22569481, PubMed:23755964), In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues (PubMed:12433996, PubMed:19170771, PubMed:22569481, PubMed:23755964)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the FPG family", "domain_description": {"FPG-type Zinc finger": 1, "RanBP2-type Zinc finger": 1, "GRF-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVEGPGCTLNGEKIRARVLPGQAVTGVRGSALRSLQGRALRLAASTVVVSPQAAALNNDSSQNVLSLFNGYVYSGVETLGKELFMYFGPKALRIHFGMKGFIMINPLEYKYKNGASPVLEVQLTKDLICFFDSSVELRNSMESQQRIRMMKELDVCSPEFSFLRAESEVKKQKGRMLGDVLMDQNVLPGVGNIIKNEALFDSGLHPAVKVCQLTDEQIHHLMKMIRDFSILFYRCRKAGLALSKHYKVYKRPNCGQCHCRITVCRFGDNNRMTYFCPHCQKENPQHVDICKLPTRNTIISWTSSRVDHVMDSVARKSEEHWTCVVCTLINKPSSKACDACLTSRPIDSVLKSEENSTVFSHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLERKTKQNQILDEEFQNSPPASVCLNDIQHPSKKTTNDITQPSSKVNISPTISSESKLFSPAHKKPKTAQYSSPELKSCNPGYSNSELQINMTDGPRTLNPDSPRCSKHNRLCILRVVGKDGENKGRQFYACPLPREAQCGFFEWADLSFPFCNHGKRSTMKTVLKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC", "length": 605, "molWeight": 67769, "crc64": "528B17873ABC9D89", "md5": "47D3BE36CFB1B1EA1916527B417D6B44"}}
{"primaryAccession": "Q8TBK2", "text": "This is N-lysine methyltransferase SETD6 protein, from Human, contains 473 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8TBK2", "organism_name": "Human", "protein_name": "N-lysine methyltransferase SETD6", "length": 473, "firstPublicDate": "2007-04-03", "FUNCTION": "Protein-lysine N-methyltransferase, Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulation of NF-kappa-B transcription factor activity (PubMed:21131967, PubMed:30189201, PubMed:21515635), Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (PubMed:23324626), Required for the maintenance of embryonic stem cell self-renewal (By similarity), Methylates PAK4", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, SETD6 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVSERAGGRRTRGGARAALTSPPAQVAVSRQGTVAGYGMVARESVQAGELLFVVPRAALLSQHTCSIGGLLERERVALQSQSGWVPLLLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIRSEYQSIVLPFMEAHPDLFSLRVRSLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPVMVPAADILNHLANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGSLTITNIPKLKASWRQLLQNSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS", "length": 473, "molWeight": 53189, "crc64": "3BFC08F0FACEAACC", "md5": "3B9053C413091A24570B55D438AFABBA"}}
{"primaryAccession": "Q8TDR4", "text": "This is T-complex protein 10A homolog 1 protein, from Human, contains 215 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8TDR4", "organism_name": "Human", "protein_name": "T-complex protein 10A homolog 1", "length": 215, "firstPublicDate": "2002-10-10", "FUNCTION": "May be involved in transcriptional regulation, Has in vitro transcription inhibition activity, Acts as a tumor suppressor in hepatocellular carcinoma (HCC) cells", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TCP10 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQELGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTLALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKTPPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV", "length": 215, "molWeight": 23863, "crc64": "CF3F74AB520F55FE", "md5": "D3D7EB195A7ACF1B31AC2A9390958F46"}}
{"primaryAccession": "Q8TDY4", "text": "This is Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 protein, from Human, contains 903 amino acids, has 1 C4-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [441, 464], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8TDY4", "organism_name": "Human", "protein_name": "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3", "length": 903, "firstPublicDate": "2006-04-18", "FUNCTION": "Promotes cell proliferation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPEQFSVAEFLAVTAEDLSSPAGAAAFAAKMPRYRGAALAREEILEGDQAILQRIKKAVRAIHSSGLGHVENEEQYREAVESLGNSHLSQNSHELSTGFLNLAVFTREVAALFKNLIQNLNNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAKMAKLEKERDRARVTGGIPGEVAQDMQRERRIFQLHMCEYLLKAGESQMKQGPDFLQSLIKFFHAQHNFFQDGWKAAQSLFPFIEKLAASVHALHQAQEDELQKLTQLRDSLRGTLQLESREEHLSRKNSGCGYSIHQHQGNKQFGTEKVGFLYKKSDGIRRVWQKRKCGVKYGCLTISHSTINRPPVKLTLLTCQVRPNPEEKKCFDLVTHNRTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTPEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQAQAGTFAFPLHVDYSWVISTEPGSDSEEDEEEKRCLLKLPAQAHWASGRLDISNKTYETVASLGAATPQGESEDCPPPLPVKNSSRTLVQGCARHASGDRSEVSSLSSEAPETPESLGSPASSSSLMSPLEPGDPSQAPPNSEEGLREPPGTSRPSLTSGTTPSEMYLPVRFSSESTRSYRRGARSPEDGPSARQPLPRRNVPVGITEGDGSRTGSLPASSVQLLQD", "length": 903, "molWeight": 99155, "crc64": "D5E89518AFC86656", "md5": "4EF5FCACD5C352CC477EFEE4DDBA8DEC"}}
{"primaryAccession": "Q8TGH6", "text": "This is Guanosine-diphosphatase protein, from Yeast, contains 599 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8TGH6", "organism_name": "Yeast", "protein_name": "Guanosine-diphosphatase", "length": 599, "firstPublicDate": "2004-04-13", "FUNCTION": "Has a role in cell wall morphogenesis during the transition of budding growth into hyphal growth, a process known as dimorphism", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GDA1/CD39 NTPase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MINPRNLRLIIAVIGLVGIFAFFASSQHSLVDRTALQVNKPAADSPHVPPPAAAAAPVSPPPPSQQQKQQEGSQKQLNDENSDEKNTLQGTSYSGTKPPYEKVDGKSNKILADKLDTTKNSKPNQQQQQNTQKGASEEKSAQNKITTPEEVSMDNGKCNDIDYVVMIDAGSTGSRVHVYEFNTCVKPPQLLSEEFEMLKPGLSSFDTDTVGAAKSLDPLLEVALKKVPKNKQSCTPVAVKATAGLRLLGETKSKAILDEVRSHLEKDYPFAVVSEDGISIMDGKDEGVYAWVTANYLLGNIGGKEKLPTAAVFDLGGGSTQIVFEPDYKVDEVPVDGETKYHFTFGDNQYTLYQFSHLGYGLMQGRNKVNQLVLKNKLSELNLQKYTKKEVKGAKATVDVSNPCIPPGVVAKDVQVELGEDEFYVVNMKGPSSKDSTVAGGSQCRYLAEKVLNKDAECTSKPCSFNGVHQPSLTRTFNKNSDMYVFSYFYDRTNPIGMPSSFSVEELKDLSKLVCQGETFWKDILLDDHVKNLNEEPQWCLDLSFITAMLHTGYDIPLHRELKTAKTIDNNELGWCLGASLPLLDKNNAKWTCRIDKTD", "length": 599, "molWeight": 65953, "crc64": "D5BC3A4F6E1B646A", "md5": "C37993BCDDDEDA192F6ACC6826ACC56C"}}
{"primaryAccession": "Q8VBV9", "text": "This is Olfactory receptor 51E2 protein, from Mouse, contains 320 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VBV9", "organism_name": "Mouse", "protein_name": "Olfactory receptor 51E2", "length": 320, "firstPublicDate": "2014-09-03", "FUNCTION": "Olfactory receptor, The activity of this receptor is probably mediated by G-proteins wich induce elevation of intracellular Ca(2+), cAMP and activation of phosphorylation of the protein kinases PKA and MAPK3/MAPK1, Activation of OR51E2 may affect melanocyte proliferation, differentiation, and melanogenesis and may increase proliferation and migration of primary retinal pigment epithelial (RPE) cells (By similarity), Activated by the short chain fatty acids (SCFA), acetate and propionate (PubMed:23401498), In response to SCFA, may positively regulate renin secretion and increase blood pressure (PubMed:23401498), May also be activated by steroid hormones and regulate cell proliferation (By similarity), Activated by L-lactate in glomus cells (PubMed:26560302, PubMed:30258151)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSCNFTHATFLLIGIPGLEEAHFWFGFPLLSMYAVALFGNCIVVFIVRTERSLHAPMYLFLCMLAAIDLALSTSTMPKILALFWFDSREITFDACLAQMFFIHTLSAIESTILLAMAFDRYVAICHPLRHAAVLNNTVTVQIGMVALVRGSLFFFPLPLLIKRLAFCHSNVLSHSYCVHQDVMKLAYTDTLPNVVYGLTAILLVMGVDVMFISLSYFLIIRTVLQLPSKSERAKAFGTCVSHISVVLAFYVPLIGLSVVHRFGNSLDPIVHVLMGDVYLLLPPVINPIIYGAKTKQIRTRVLAMFKISCDKDIEAGGNT", "length": 320, "molWeight": 35578, "crc64": "7161ACA8F4328959", "md5": "F2F41BAB53595E3FC69A536B14DDF2B2"}}
{"primaryAccession": "Q8VC69", "text": "This is Solute carrier family 22 member 6 protein, from Mouse, contains 545 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VC69", "organism_name": "Mouse", "protein_name": "Solute carrier family 22 member 6", "length": 545, "firstPublicDate": "2008-03-18", "FUNCTION": "Involved in the renal elimination of endogenous and exogenous organic anions, Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc), Mediates the transport of prostaglandin E2 (PGE2) and prostaglandin F2-alpha (PGF2-alpha) and may be involved in their renal excretion (By similarity), May contribute to the transport of organic compounds in testes across the blood-testis-barrier (By similarity), Also mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) and edaravone sulfate (By similarity), Mediates the sodium-independent uptake of p-aminohippurate (PAH), PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, bumetamide, losartan, probenecid, phenol red, urate, glutarate and alpha-ketoglutarate (By similarity), PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), indomethacin, sulindac, diclofenac, carprofen, okadaic acid and PKC activators", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPAHHCRPPANANLSKDGGLEAWLPLDKQGRPESCLRFPFPHNGTEANGTGVTEPCLDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLFMVGVLLGAMMFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCIFRLLSGMSLASIAINCMTLNMEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLAVSVPFFVAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLQTSLQKELTLNKGQASAMELLRCPTLRRLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQLASLLLAGICILVNGIIPRGHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTAEFYPSIPLFIFGAVPVAASAVTALLPETLGQPLPDTVQDLKSRSRGKQKQQQLEQQKQMIPLQVSTQEKNGL", "length": 545, "molWeight": 60013, "crc64": "827782E115705C77", "md5": "D979C40053E9F996BBD3DE0EA7569172"}}
{"primaryAccession": "Q8VDW4", "text": "This is Ubiquitin-conjugating enzyme E2 W protein, from Mouse, contains 151 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VDW4", "organism_name": "Mouse", "protein_name": "Ubiquitin-conjugating enzyme E2 W", "length": 151, "firstPublicDate": "2006-04-18", "FUNCTION": "Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, Specifically monoubiquitinates the N-terminus of various substrates, including ATXN3, MAPT/TAU, POLR2H/RPB8 and STUB1/CHIP, by recognizing backbone atoms of disordered N-termini (PubMed:21855799, PubMed:21229326), Involved in degradation of misfolded chaperone substrates by mediating monoubiquitination of STUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length of ubiquitin chain attached to STUB1/CHIP substrates by ATXN3 (PubMed:21855799), After UV irradiation, but not after mitomycin-C (MMC) treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway (PubMed:21229326), In vitro catalyzes 'Lys-11'-linked polyubiquitination, UBE2W-catalyzed ubiquitination occurs also in the presence of inactive RING/U-box type E3s, i,e, lacking the active site cysteine residues to form thioester bonds with ubiquitin, or even in the absence of E3, albeit at a slower rate (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ubiquitin-conjugating enzyme family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASMQKRLQKELLALQNDPPPGMTLNEKSVQNSITQWIVDMEGAPGTLYEGEKFQLLFKFSSRYPFDSPQVMFTGENIPIHPHVYSNGHICLSILTEDWSPALSVQSVCLSIISMLSSCKEKRRPPDNSFYVRTCNKNPKKTKWWYHDDTC", "length": 151, "molWeight": 17345, "crc64": "FCC840E01F4CEB63", "md5": "12219F5115C2DABEA4AAE2F4450C2B7B"}}
{"primaryAccession": "Q8VE43", "text": "This is Meteorin-like protein protein, from Mouse, contains 311 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VE43", "organism_name": "Mouse", "protein_name": "Meteorin-like protein", "length": 311, "firstPublicDate": "2007-05-29", "FUNCTION": "Hormone induced following exercise or cold exposure that promotes energy expenditure, Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation, Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance, Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions, Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat, Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the meteorin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGAVWAARRRAGQQWPRSPGPGPGPPPPPPLLLLLLLLLGGASAQYSSDLCSWKGSGLTREARSKEVEQVYLRCSAGSVEWMYPTGALIVNLRPNTFSPAQNLTVCIKPFRDSSGANIYLEKTGELRLLVRDIRGEPGQVQCFSLEQGGLFVEATPQQDISRRTTGFQYELMSGQRGLDLHVLSAPCRPCSDTEVLLAICTSDFVVRGFIEDVTHVPEQQVSVIYLRVNRLHRQKSRVFQPAPEDSGHWLGHVTTLLQCGVRPGHGEFLFTGHVHFGEAQLGCAPRFSDFQRMYRKAEEMGINPCEINME", "length": 311, "molWeight": 34530, "crc64": "C8062688E2B6DFA0", "md5": "5E6F4DC7BF5FAD700DE23DBCA1F0BFF6"}}
{"primaryAccession": "Q8VEN2", "text": "This is Placenta-expressed transcript 1 protein protein, from Mouse, contains 237 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VEN2", "organism_name": "Mouse", "protein_name": "Placenta-expressed transcript 1 protein", "length": 237, "firstPublicDate": "2008-02-26", "FUNCTION": "Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair, May play a role during trichilemmal differentiation of the hair follicle", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLSLRSLLPHLGLFLCLALHLSPSLSASDNGSCVVLDNIYTSDILEISTMANVSGGDVTYTVTVPVNDSVSAVILKAVKEDDSPVGTWSGTYEKCNDSSVYYNLTSQSQSVFQTNWTVPTSEDVTKVNLQVLIVVNRTASKSSVKMEQVQPSASTPIPESSETSQTINTTPTVNTAKTTAKDTANTTAVTTANTTANTTAVTTAKTTAKSLAIRTLGSPLAGALHILLVFLISKLLF", "length": 237, "molWeight": 25006, "crc64": "CF6E144B6D9C902B", "md5": "362B585434335A6AA8958ED6B9DB74E8"}}
{"primaryAccession": "Q8VYF7", "text": "This is Single-stranded DNA-binding protein WHY2, mitochondrial protein, from Mouse-ear cress, contains 238 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VYF7", "organism_name": "Mouse-ear cress", "protein_name": "Single-stranded DNA-binding protein WHY2, mitochondrial", "length": 238, "firstPublicDate": "2012-11-28", "FUNCTION": "Single-stranded DNA-binding protein that associates with mitochondrial DNA and may play a role in the regulation of the gene expression machinery, Seems also to be required to prevent break-induced DNA rearrangements in the mitochondrial genome, Can bind to melt double-stranded DNA in vivo", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the Whirly family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMKQARSLLSRSLCDQSKSLFEASTLRGFASWSNSSTPGRGFPGKDAAKPSGRLFAPYSIFKGKAALSVEPVLPSFTEIDSGNLRIDRRGSLMMTFMPAIGERKYDWEKKQKFALSPTEVGSLISMGSKDSSEFFHDPSMKSSNAGQVRKSLSVKPHADGSGYFISLSVNNSILKTNDYFVVPVTKAEFAVMKTAFSFALPHIMGWNRLTGHVNTEALPSRNVSHLKTEPQLELEWDK", "length": 238, "molWeight": 26295, "crc64": "F5586CABDABF4E02", "md5": "4E887D8AC79662608C9758F88051DA9E"}}
{"primaryAccession": "Q8VZ20", "text": "This is Trihelix transcription factor ASR3 protein, from Mouse-ear cress, contains 314 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VZ20", "organism_name": "Mouse-ear cress", "protein_name": "Trihelix transcription factor ASR3", "length": 314, "firstPublicDate": "2015-09-16", "FUNCTION": "Transcriptional repressor that binds DNA and plays a negative role in regulating microbe-associated molecular patterns-(MAMPs, e,g, flg22, elf18, chitin, and LPS) triggered immunity (PTI) by negatively regulating immune gene expression", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALEQLGLGVSAVDGGENSSAPSNDGGDDGVKTARLPRWTRQEILVLIQGKRVAENRVRRGRAAGMALGSGQMEPKWASVSSYCKRHGVNRGPVQCRKRWSNLAGDYKKIKEWESQIKEETESYWVMRNDVRREKKLPGFFDKEVYDIVDGGVIPPAVPVLSLGLAPASDEGLLSDLDRRESPEKLNSTPVAKSVTDVIDKEKQEACVADQGRVKEKQPEAANVEGGSTSQEERKRKRTSFGEKEEEEEEGETKKMQNQLIEILERNGQLLAAQLEVQNLNLKLDREQRKDHGDSLVAVLNKLADAVAKIADKM", "length": 314, "molWeight": 34861, "crc64": "4F08D028F187B413", "md5": "390B4B99ADFEAD89807CA0361E3CBAD6"}}
{"primaryAccession": "Q8W2F3", "text": "This is Transcription factor PIF4 protein, from Mouse-ear cress, contains 430 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8W2F3", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor PIF4", "length": 430, "firstPublicDate": "2003-02-01", "FUNCTION": "Transcription factor acting negatively in the phytochrome B signaling pathway, May regulate the expression of a subset of genes involved in cell expansion by binding to the G-box motif (By similarity), Activated by CRY1 and CRY2 in response to low blue light (LBL) by direct binding at chromatin on E-box variant 5'-CA[CT]GTG-3' to stimulate specific gene expression to adapt global physiology (e,g, hypocotyl elongation in low blue light) (PubMed:26724867)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bHLH protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEHQGWSFEENYSLSTNRRSIRPQDELVELLWRDGQVVLQSQTHREQTQTQKQDHHEEALRSSTFLEDQETVSWIQYPPDEDPFEPDDFSSHFFSTMDPLQRPTSETVKPKSSPEPPQVMVKPKACPDPPPQVMPPPKFRLTNSSSGIRETEMEQYSVTTVGPSHCGSNPSQNDLDVSMSHDRSKNIEEKLNPNASSSSGGSSGCSFGKDIKEMASGRCITTDRKRKRINHTDESVSLSDAIGNKSNQRSGSNRRSRAAEVHNLSERRRRDRINERMKALQELIPHCSKTDKASILDEAIDYLKSLQLQLQVMWMGSGMAAAAASAPMMFPGVQPQQFIRQIQSPVQLPRFPVMDQSAIQNNPGLVCQNPVQNQIISDRFARYIGGFPHMQAATQMQPMEMLRFSSPAGQQSQQPSSVPTKTTDGSRLDH", "length": 430, "molWeight": 48363, "crc64": "B4C081D0BF907C26", "md5": "FE07A7F0961F031F2AD3284E1DD07DA6"}}
{"primaryAccession": "Q8W4D0", "text": "This is Peptidyl-prolyl cis-trans isomerase CYP71 protein, from Mouse-ear cress, contains 631 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8W4D0", "organism_name": "Mouse-ear cress", "protein_name": "Peptidyl-prolyl cis-trans isomerase CYP71", "length": 631, "firstPublicDate": "2014-07-09", "FUNCTION": "PPIases accelerate the folding of proteins (Probable), It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:33098102), Histone proline isomerase that increases the rate of cis-trans isomerization of the synthetic histone H3 peptides H3P30 (RKSAP30F-p-nitroanilide) and H3P30K27me3 (RKme3-SAP30F-p-nitroanilide) in the histone H3 N-terminal tail, in vitro (PubMed:33098102), Histone remodeling factor involved in chromatin-based gene silencing (PubMed:17704213), Reinforces H3K27 methylation (PubMed:17704213), Involved in fundamental processes of chromatin assembly and histone modification by mediating the targeting of FAS1 and LHP1 on the chromatin (PubMed:21596687), Required for the formation and development of leaves, for normal phyllotaxy and for the formation, maintenance and activity of root and shoot apical meristems (PubMed:17704213)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the cyclophilin-type PPIase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEEESKNGGTTIPTEELAVVAVPPVVEEEEPMVGPGPAPRGKRKRPLQFEQAYLDSLPSANMYEKSYMHRDVVTHVAVSAAEFFISGSMDGHLKFWKKKGVGIEFAKHFRSHLGPIEGLAVSIDGLLCCTISNDHAVKIYDVVNYDMMAMIRLPYIPGAVEWVYKQGDVKAKLAVSDRDSLFVHIYDPRSGSNEPIASKEIHMNPIKVMKYNPVSDTMISGDTKGIIEYWSATTLQFPEDEVNFKLKSDTNLFEIIKCKTTISAIEVSPDGKQFSITAPDRRIRVFWFRTGKLRRVYDESLVVAQDLQRSDAPLYRLEAIDFGRRMAVEKELEKTESAPQPNAVFDESSNFLIYATFLGIKVINLHTNTVARILGKVESNERYLRVALYQGDQGGKKVRKIPAAAANVNESKEPLTDPTILCCAFKKHRIYMFSRREPEEPEDASQGRDVFNEKPAADELMSVSDIGNSATTSLPENVIMHTTLGDIHMKLYPEECPKTVENFTTHCRNGYYDNHLFHRVIRGFMIQTGDPLGDGTGGQSIWGREFEDEFHKSLRHDRPFTLSMANAGPNTNGSQFFITTVATPWLDNKHTVFGRVVKGMDVVQGIEKVKTDKNDRPYQDVKILNVTVPKS", "length": 631, "molWeight": 70984, "crc64": "15CCAD94C2EA09D4", "md5": "F6BF3190FDD49EDA79CED4CA5A844E53"}}
{"primaryAccession": "Q8W4D8", "text": "This is FHA domain-containing protein DDL protein, from Mouse-ear cress, contains 314 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8W4D8", "organism_name": "Mouse-ear cress", "protein_name": "FHA domain-containing protein DDL", "length": 314, "firstPublicDate": "2010-03-02", "FUNCTION": "Involved in the microRNA (miRNA) and short interfering RNA (siRNA) biogenesis, May facilitate DCL1 to access or recognize primary miRNAs, Binds RNA non-specifically", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAPSSRSPSPRTKRLRRARGEKEIGRSREREDDGREREKRNSRERDRDIGRDRDRERKGEGERDREVGDKRRRSGREDTEKRRRTRTDDERYSRGRHERSTSPSDRSHRSSRRSPERAIASRHDEGSNARGGSEEPNVEEDSVARMRAVEEALAAKKKEEPSFELSGKLAEETNRYRGITLLFNEPPEARKPSERWRLYVFKDGEPLNEPLCLHRQSCYLFGRERRIADIPTDHPSCSKQHAVIQYREMEKEKPDGMMGKQVKPYIMDLGSTNKTYINESPIEPQRYYELFEKDTIKFGNSSREYVLLHENSAE", "length": 314, "molWeight": 36953, "crc64": "42F3A7C9DFF14B68", "md5": "7BCD8E8752501EBDDC5EE555395C27DF"}}
{"primaryAccession": "Q8W4P8", "text": "This is Membrane protein of ER body 1 protein, from Mouse-ear cress, contains 611 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8W4P8", "organism_name": "Mouse-ear cress", "protein_name": "Membrane protein of ER body 1", "length": 611, "firstPublicDate": "2014-10-01", "FUNCTION": "May sequester excess cytosolic iron and manganese into endoplasmic reticulum to reduce metal ion toxicity, Not essential for the accumulation of ER body components, including PYK10", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the CCC1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDPTMNPTPTPSSAGNSVCTDELTNLPPEDSPLDSEKDDSVDFSQEQGSESNEAIDTENGSRSVDKNQYSETEVVVRAKDLQTEPDSLDDDVEIVIKNQHKYYIYCPCCGEDITKTVKLVKISDPKHTKDHDKAVDSDTENGSKSKDKNTKVPSWFSDFIQPLFSSEDRGKKGVVDSELLGTYEDLGIIGEEPSIDVSNEKDRPSFPKWYLDVFAWLFLCIIIALSVLSTSPPPFIQPHLQLPSMPTLRMPSASVLLLLPTSAVLLLFIISMRSRFTPRYHKEKGEVVPKSTDSKSHDDQAANTDQDFDKKTDNKRNRLTPIYPSSLEKPSKQTVNKETQNHDKEAADPDQDVDKETENQKSHLTPIYPSPLEQPSKQIINKETQTEPMLPPNAQSEIPNSVEPRKGGNKVEILKSIVYGGLTESITSLCTVTSAAASGASTLNVLALGVANLSSGLLLTVHSLQELINEKPRKQTNTDDSPEEGEGEEDRYEEVLGRREYSRIHRVIAISSFVIFGLIPPLVYGFSFRKKMEKRQEYKVLAVYAVSLLCIVLLSIAKAYVSKKRDYVKTLFRYTTTATTASGFSQFVGYLVSQWLEKSGFYDDSPETQRV", "length": 611, "molWeight": 68170, "crc64": "7E154E953D9DCFCD", "md5": "FE93FC811F9D05994C764769E61441A3"}}
{"primaryAccession": "Q8WN93", "text": "This is Calcitonin gene-related peptide type 1 receptor protein, from Pig, contains 462 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WN93", "organism_name": "Pig", "protein_name": "Calcitonin gene-related peptide type 1 receptor", "length": 462, "firstPublicDate": "2009-05-05", "FUNCTION": "Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3, The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEKKYILYFLFLLPFFMILVIAETEEENPDDLIQLTVTRNKIMTAQYECYQKIMQDPIQQTEGIYCNRTWDGWLCWNDVAAGTESMQHCPDYFQDFDPSEKVTKICDQDGNWFRHPESNRTWTNYTQCNINTHEKVQTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSIVTIIHLTAVANNQALVATNPVSCKVFQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAVARRLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILVHYQGLLVSTIYCFFNGEVQAILRRNWNQYKIQFGNSFSHSDALRSASYTVSTISDGAGYSHDYPSEHLNGKSIHDMENIVIKPEKLYD", "length": 462, "molWeight": 53656, "crc64": "4585B314015B43AC", "md5": "EE55AC19E5071BAA4B2775CCE2C258F6"}}
{"primaryAccession": "Q8WQL7", "text": "This is Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1 protein, from Caenorhabditis elegans, contains 882 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WQL7", "organism_name": "Caenorhabditis elegans", "protein_name": "Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1", "length": 882, "firstPublicDate": "2010-01-19", "FUNCTION": "Possible role in the function of olfactory neurons", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNTADVPDNLQSWGQQPSSSYSNTQQHSQMTNLPPINHNNLCDTEPMNEDFQLQDVQADELQKQQKQQEQQHIQQQNAQRFIAQSRQPHSNILRFPQPPITSIKTNSHAFYPQQEVTQVRPKKHRVSMTNAEAALTPGMPPEKQAAKKRNIGQFSTDTVPAGIGMIGIPFESTSKPLQIQQFRNPQDAPVRKLTSDLIKTYKAINESFYLRKQVRRDRHKSQDAGKPKGSKDGSGASLTDTFSIHNAIPITSSDNHYQQDAHQNAPPLLDTNAPPTSTMVVPMRTETDLQQQQRQKSSRGGPYNNGYDDQNYDYILKNGEIFDKRYVILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNTSFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMHTGEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSVEDYSKFKDLIKRMLQFDPKQRISPYYVVRHPFLKQKEERVPSQPPVSHSNLQQQQQLYIQQPSSQMSQVMESPSVGSVYVEDNGMYRQAPGSSANPISVTSSFDEGDAMEVDAGRRRFSAHQQNYHNPNYQYSQPQQQQQQQYQQTQRTQLEQQQKQAQLQQQLQQQQMQQQQQQQQQRQHMPQAQSSSQQHLQSRARPRQQDQNEWRNQFELDDTFQQKQRKVDDSVSNQISRNQFNPQQVSMTHGNVNANNREMEKLDYPNNKL", "length": 882, "molWeight": 101244, "crc64": "DD5C9DD354DA7098", "md5": "2ABCE09B53055E609E9B18FC3C334BCC"}}
{"primaryAccession": "Q8WUQ7", "text": "This is Splicing factor Cactin protein, from Human, contains 758 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WUQ7", "organism_name": "Human", "protein_name": "Splicing factor Cactin", "length": 758, "firstPublicDate": "2006-04-04", "FUNCTION": "Plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (PubMed:28062851), Required for the splicing of CDCA5/Sororin, a regulator of sister chromatid cohesion (PubMed:28062851), Involved in the regulation of innate immune response (PubMed:20829348), Acts as negative regulator of Toll-like receptor, interferon-regulatory factor (IRF) and canonical NF-kappa-B signaling pathways (PubMed:20829348, PubMed:26363554), Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (PubMed:20829348, PubMed:26363554)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CACTIN family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGRDTRSRSRSAGRRGRRRQSQSGSRSRSRSHGRRNRRRREDEGRRRRRRRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELMKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGPNLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYSPRLLTAHELPLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR", "length": 758, "molWeight": 88702, "crc64": "F540F151EB96BEFB", "md5": "BF93E1AB9FBC93900F24015BAB62F11F"}}
{"primaryAccession": "Q8WUU5", "text": "This is GATA zinc finger domain-containing protein 1 protein, from Human, contains 269 amino acids, has 1 GATA-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [9, 33], "description": "GATA-type", "keyword_description": "Zinc finger", "textural_description": "GATA-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8WUU5", "organism_name": "Human", "protein_name": "GATA zinc finger domain-containing protein 1", "length": 269, "firstPublicDate": "2007-05-29", "FUNCTION": "Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"GATA-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPLGLKPTCSVCKTTSSSMWKKGAQGEILCHHCTGRGGAGSGGAGSGAAGGTGGSGGGGFGAATFASTSATPPQSNGGGGGKQSKQEIHRRSARLRNTKYKSAPAAEKKVSTKGKGRRHIFKLKNPIKAPESVSTIITAESIFYKGVYYQIGDVVSVIDEQDGKPYYAQIRGFIQDQYCEKSAALTWLIPTLSSPRDQFDPASYIIGPEEDLPRKMEYLEFVCHAPSEYFKSRSSPFPTVPTRPEKGYIWTHVGPTPAITIKESVANHL", "length": 269, "molWeight": 28690, "crc64": "7DFA569A731D9003", "md5": "1F6E747D7D4656C1141010B8D1F8EC25"}}
{"primaryAccession": "Q8WV22", "text": "This is Non-structural maintenance of chromosomes element 1 homolog protein, from Human, contains 266 amino acids, has 1 RING-type; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [191, 232], "description": "RING-type; atypical", "keyword_description": "Zinc finger", "textural_description": "RING-type; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q8WV22", "organism_name": "Human", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "length": 266, "firstPublicDate": "2007-01-09", "FUNCTION": "RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate, Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex, Involved in maintenance of genome integrity, DNA damage response and DNA repair (PubMed:29225034, PubMed:20864041), NSMCE3/MAGEG1 and NSMCE1 ubiquitin ligase are components of SMC5-SMC6 complex and may positively regulate homologous recombination-mediated DNA repair (PubMed:18086888), MAGEF1-NSMCE1 ubiquitin ligase promotes proteasomal degradation of MMS19, a key component of the cytosolic iron-sulfur protein assembly (CIA) machinery, Down-regulation of MMS19 impairs the activity of several DNA repair and metabolism enzymes such as ERCC2/XPD, FANCJ, RTEL1 and POLD1 that require iron-sulfur clusters as cofactors (PubMed:29225034)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the NSE1 family", "domain_description": {"RING-type; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQGSTRRMGVMTDVHRRFLQLLMTHGVLEEWDVKRLQTHCYKVHDRNATVDKLEDFINNINSVLESLYIEIKRGVTEDDGRPIYALVNLATTSISKMATDFAENELDLFRKALELIIDSETGFASSTNILNLVDQLKGKKMRKKEAEQVLQKFVQNKWLIEKEGEFTLHGRAILEMEQYIRETYPDAVKICNICHSLLIQGQSCETCGIRMHLPCVAKYFQSNAEPRCPHCNDYWPHEIPKVFDPEKERESGVLKSNKKSLRSRQH", "length": 266, "molWeight": 30855, "crc64": "58A3C2AF70FC8F39", "md5": "A97D57A64F75C21FE5E67CF01F38086A"}}
{"primaryAccession": "Q8WVX9", "text": "This is Fatty acyl-CoA reductase 1 protein, from Human, contains 515 amino acids, is membrane-bound, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WVX9", "organism_name": "Human", "protein_name": "Fatty acyl-CoA reductase 1", "length": 515, "firstPublicDate": "2006-11-28", "FUNCTION": "Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols (PubMed:15220348, PubMed:24108123), It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols (PubMed:20071337, PubMed:24108123, PubMed:33239752), In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis (By similarity)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the fatty acyl-CoA reductase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVSIPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSGKLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNENLRDAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILRTIRASNNALADLVPVDVVVNMSLAAAWYSGVNRPRNIMVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDIYLRMTGRSPRMMKTITRLHKAMVFLEYFTSNSWVWNTENVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCLGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYFVVSLCYKFLSYFRASSTMRY", "length": 515, "molWeight": 59357, "crc64": "EF5CF7CDD161BCD3", "md5": "EA10D0883DC375DCEDD51E8F6CC0760A"}}
{"primaryAccession": "Q8WW12", "text": "This is PEST proteolytic signal-containing nuclear protein protein, from Human, contains 178 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WW12", "organism_name": "Human", "protein_name": "PEST proteolytic signal-containing nuclear protein", "length": 178, "firstPublicDate": "2005-06-07", "FUNCTION": "May be involved in cell cycle regulation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MADGKAGDEKPEKSQRAGAAGGPEEEAEKPVKTKTVSSSNGGESSSRSAEKRSAEEEAADLPTKPTKISKFGFAIGSQTTKKASAISIKLGSSKPKETVPTLAPKTLSVAAAFNEDEDSEPEEMPPEAKMRMKNIGRDTPTSAGPNSFNKGKHGFSDNQKLWERNIKSHLGNVHDQDN", "length": 178, "molWeight": 18925, "crc64": "B79D49B362892AE1", "md5": "FD930C3B3CD73C42FFF1FA0281C011F3"}}
{"primaryAccession": "Q8WWF5", "text": "This is E3 ubiquitin-protein ligase ZNRF4 protein, from Human, contains 429 amino acids, has 1 RING-type; atypical Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [309, 352], "description": "RING-type; atypical", "keyword_description": "Zinc finger", "textural_description": "RING-type; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q8WWF5", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase ZNRF4", "length": 429, "firstPublicDate": "2007-02-20", "FUNCTION": "E3 ubiquitin-protein ligase that acts as a negative regulator of NOD2 signaling by mediating ubiquitination and degradation of RIPK2 (PubMed:28656966), Also catalyzes ubiquitination and proteasomal degradation of CANX within the endoplasmic reticulum (PubMed:21205830), Could have a role in spermatogenesis (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {"RING-type; atypical Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPLCRPEHLMPRASRVPVAASLPLSHAVIPTQLPSRPGHRPPGRPRRCPKASCLPPPVGPSSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALFGVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGAIVLIRRYDCTFDLKVLNAQRAGFEAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDDPPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVRTFTWHNDLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSVAATEDSFDSTTYSFRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSLEAEYTTVSSAPPEAPGQ", "length": 429, "molWeight": 46958, "crc64": "9924ED37BC00644D", "md5": "48801939D9C11A9AAA0A72254FB85588"}}
{"primaryAccession": "Q8WWQ2", "text": "This is Inactive heparanase-2 protein, from Human, contains 592 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WWQ2", "organism_name": "Human", "protein_name": "Inactive heparanase-2", "length": 592, "firstPublicDate": "2005-10-25", "FUNCTION": "Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity, Inhibits HPSE, possibly by competing for its substrates (in vitro)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 79 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQAGDRRPLPVDRAAGLKEKTLILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREKAAQMHLVLLKEQFSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR", "length": 592, "molWeight": 66596, "crc64": "95C384AD9A6C868E", "md5": "B6CBA0C66D337EC7C9AE37136C41C91D"}}
{"primaryAccession": "Q8WWZ8", "text": "This is Oncoprotein-induced transcript 3 protein protein, from Human, contains 545 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WWZ8", "organism_name": "Human", "protein_name": "Oncoprotein-induced transcript 3 protein", "length": 545, "firstPublicDate": "2007-08-21", "FUNCTION": "May be involved in hepatocellular function and development", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPPFLLLTCLFITGTSVSPVALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWYHFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVSNGTHVNILFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESLVESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQTLTGGPIRIDWED", "length": 545, "molWeight": 60022, "crc64": "E4BDE126213484B0", "md5": "DB14D63A8DB404FE086330D807F6E5CC"}}
{"primaryAccession": "Q8WXF8", "text": "This is DNA-binding death effector domain-containing protein 2 protein, from Human, contains 326 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WXF8", "organism_name": "Human", "protein_name": "DNA-binding death effector domain-containing protein 2", "length": 326, "firstPublicDate": "2004-05-10", "FUNCTION": "May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus, May regulate degradation of intermediate filaments during apoptosis, May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALSGSTPAPCWEEDECLDYYGMLSLHRMFEVVGGQLTECELELLAFLLDEAPGAAGGLARARSGLELLLELERRGQCDESNLRLLGQLLRVLARHDLLPHLARKRRRPVSPERYSYGTSSSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGRPSGGARRRRRGAPAAPQQQSEPARPSSEGKVTCDIRLRVRAEYCEHGPALEQGVASRRPQALARQLDVFGQATAVLRSRDLGSVVCDIKFSELSYLDAFWGDYLSGALLQALRGVFLTEALREAVGREAVRLLVSVDEADYEAGRRRLLLMEEEGGRRPTEAS", "length": 326, "molWeight": 36179, "crc64": "3F7B0B307CC870CD", "md5": "2280491F936714D98EC6D6406D44502E"}}
{"primaryAccession": "Q8WYH8", "text": "This is Inhibitor of growth protein 5 protein, from Human, contains 240 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [186, 235], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8WYH8", "organism_name": "Human", "protein_name": "Inhibitor of growth protein 5", "length": 240, "firstPublicDate": "2005-01-04", "FUNCTION": "Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4 (PubMed:24065767), Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:16387653), Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator (PubMed:12750254, PubMed:16387653), Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner (PubMed:21750715)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ING family", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQRVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDKMEGSDFESSGGRGLKKGRGQKEKRGSRGRGRRTSEEDTPKKKKHKGGSEFTDTILSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCPRCVQEKRKKK", "length": 240, "molWeight": 27751, "crc64": "B66DA23209EE9B9E", "md5": "BB446C9C18CBA25DCA58F50C727AB704"}}
{"primaryAccession": "Q8WYQ3", "text": "This is Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial protein, from Human, contains 142 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WYQ3", "organism_name": "Human", "protein_name": "Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial", "length": 142, "firstPublicDate": "2006-10-31", "FUNCTION": "May be involved in the maintenance of mitochondrial organization and mitochondrial cristae structure", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPRGSRSAASRPASRPAAPSAHPPAHPPPSAAAPAPAPSGQPGLMAQMATTAAGVAVGSAVGHVMGSALTGAFSGGSSEPSQPAVQQAPTPAAPQPLQMGPCAYEIRQFLDCSTTQSDLSLCEGFSEALKQCKYYHGLSSLP", "length": 142, "molWeight": 14149, "crc64": "A3AA3894CBEC0137", "md5": "34C91C5FED7644ACCADC899544394C44"}}
{"primaryAccession": "Q8X150", "text": "This is Manganese lipoxygenase protein, from Wheat and barley take-all root rot fungus, contains 618 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8X150", "organism_name": "Wheat and barley take-all root rot fungus", "protein_name": "Manganese lipoxygenase", "length": 618, "firstPublicDate": "2016-05-11", "FUNCTION": "Lipoxygenase that metabolizes linoleic and alpha-linolenic acids to 11S- and 13R-hydroperoxy fatty acids, At the end of lipoxygenation, the intermediate product 11S-HPODE from linoleic acid is then transformed into 13R-HPODE as the final product, It also acts on alpha-linolenic acid producing 11S-HPOTrE and 13R-HPOTrE with subsequent transformation of 11S-HPOTrE to 13R-HPOTrE as the final product, Gamma-linolenic acid is a poor substrate, Oleate and arachidonate are not substrates", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the lipoxygenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRSRILAIVFAARHVAALPLAAEDAAATLSLTSSASSTTVLPSPTQYTLPNNDPNQGARNASIARKRELFLYGPSTLGQTTFYPTGELGNNISARDVLLWRQDAANQTATAYREANETFADITSRGGFKTLDDFALLYNGHWKESVPEGISKGMLSNYTSDLLFSMERLSSNPYVLKRLHPTKDKLPFSVESKVVKKLTATTLEALHKGGRLFLVDHSYQKKYTPQPGRYAAACQGLFYLDARSNQFLPLAIKTNVGADLTYTPLDDKNDWLLAKIMFNNNDLFYSQMYHVLFHTIPEIVHEAAFRTLSDRHPVMGVLNRLMYQAYAIRPVGGAVLFNPGGFWDQNFGLPASAAIDFPGSVYAQGGGGFQAGYLEKDLRSRGLVGEDSGPRLPHFPFYEDAHRLIGAIRRFMQAFVDSTYGADDGDDGALLRDYELQNWIAEANGPAQVRDFPAAPLRRRAQLVDVLTHVAWVTGGAHHVMNQGSPVKFSGVVPLHPAALYAPIPTTKGATGNGTRAGLLAWLPNERQAVEQVSLLARFNRAQVGDRKQTVRDAFAAPDLLAGNGPGYAAANARFVEDTGRISREMAGRGFDGKGLSQGMPFVWTALNPAVNPFFLSV", "length": 618, "molWeight": 67620, "crc64": "ABC5229CA8F86F37", "md5": "5593D86B0342C191D4CE0655F455C7B6"}}
{"primaryAccession": "Q8X151", "text": "This is Manganese lipoxygenase protein, from Oat take-all root rot fungus, contains 618 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8X151", "organism_name": "Oat take-all root rot fungus", "protein_name": "Manganese lipoxygenase", "length": 618, "firstPublicDate": "2014-10-01", "FUNCTION": "Lipoxygenase that metabolizes linoleic and alpha-linolenic acids to 11S- and 13R-hydroperoxy fatty acids, At the end of lipoxygenation, the intermediate product 11S-HPODE from linoleic acid is then transformed into 13R-HPODE as the final product, It also acts on alpha-linolenic acid producing 11S-HPOTrE and 13R-HPOTrE with subsequent transformation of 11S-HPOTrE to 13R-HPOTrE as final product", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the lipoxygenase family, Manganese lipoxygenase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRSRILAIVFAARHVAALPLAAEDAAATLSLTSSASSTTVLPSPTQYTLPNNDPNQGARNASIARKRELFLYGPSTLGQTTFYPTGELGNNISARDVLLWRQDAANQTATAYREANETFADITSRGGFKTLDDFALLYNGHWKESVPEGISKGMLSNCTSDLLFSMERLSSNPYVLKRLHPTKDKLPFSVESKVVKKLTATTLEALHKGGRLFLVDHSYQKKYTPQPGRYAAACQGLFYLDARSNQFLPLAIKTNVGVDLTYTPLDDKDDWLLAKIMFNNNDLFYSQMYHVLFHTIPEIVHEAAFRTLSDRHPVMGVLNRLMYQAYAIRPVGGAVLFNPGGFWDQNFGLPASAAIDFPGSVYAQGGGGFQAGYLEKDLRSRGLIGEDSGPRLPHFPFYEDAHRLIGAIRRFMQAFVDSTYGADDGDDGALLRDYELQNWIAEANGPAQVRDFPAAPLRRRAQLVDVLTHVAWITGGAHHVMNQGSPVKFSGVLPLHPAALYAPIPTAKGATGNGTRAGLLAWLPNERQAVEQVSLLARFNRAQVGDRKQTVRDAFAAPDLLAGNGPGYAAANARFVEDTGRISREIAGRGFDGKGLSQGMPFVWTALNPAVNPFFLSV", "length": 618, "molWeight": 67583, "crc64": "466CFB2801B1D6F2", "md5": "5F023996C105775288420837417858F2"}}
{"primaryAccession": "Q90738", "text": "This is Actin filament-associated protein 1 protein, from Chicken, contains 729 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q90738", "organism_name": "Chicken", "protein_name": "Actin filament-associated protein 1", "length": 729, "firstPublicDate": "2008-02-05", "FUNCTION": "Functions as an adapter molecule that links other proteins to the actin cytoskeleton, May function in facilitating interactions between SRC and actin filaments, May modulate changes in actin filament integrity and induce lamellipodia formation, Can cross-link actin filaments into both network and bundle structures", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFEIKEHVQKPEVANSLPAPPQMPLPEIPQQWLPPDNGPPPLPTSSLPEGYYEEAVPVSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKMRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKENKLLCYKSSKDQQPQMELLLNDCSITYIPKDSKKKKHELKISHQGADALVLAVQSKEQAEQWLKVIKDVCSNCTGTVDSDGPLSSSPVHKTELEKKLSSERPSSDGEGAVENGITTVCNGKEQVKRKKSSKTEAKGTVTKVTGKKITKIIGLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNNRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGMLLAETGSSTDPGALHYDYIDVEMTASVIQAAKQTFCFMNRRVISTNPYRGSTANGYACPSGMALHYDDVPCINGSFKGKKPPATANGITGKVRTLNSQPKKPESVSCVKRTASNAEQYKYGKNRVEAVAKRLQSKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKTQVILEDKLKKLEEECKTKEAERVNLELELTEVKESLKKALAGGITLGLAIEPKSGTSSPQSPIFKHRTLENSPISSCDTSDTECSIPVNSAAALKRPPSSNNSPCRGHVLRKAKEWEMKNGT", "length": 729, "molWeight": 81160, "crc64": "4735A746E665890B", "md5": "443F5E0C3C4F5F1B014150D8A24027EC"}}
{"primaryAccession": "Q90WZ1", "text": "This is Kininogen-1b protein, from Giant fire-bellied toad, contains 208 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q90WZ1", "organism_name": "Giant fire-bellied toad", "protein_name": "Kininogen-1b", "length": 208, "firstPublicDate": "2005-01-04", "FUNCTION": "In vitro, produces constriction of guinea pig ileum smooth muscle, May target bradykinin receptors (BDKRB)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the bradykinin-related peptide family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRLWFCLSFFIVLCLEHFPETLADERNVPESEEKTEQYLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSLRDLPKINRKGPRPPGFSPFRGKFHSQSHV", "length": 208, "molWeight": 24104, "crc64": "4EA9A7773E22711D", "md5": "E84DE849D23823C765FE7A7351C25139"}}
{"primaryAccession": "Q90X64", "text": "This is Vang-like protein 2-A protein, from African clawed frog, contains 521 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q90X64", "organism_name": "African clawed frog", "protein_name": "Vang-like protein 2-A", "length": 521, "firstPublicDate": "2007-04-03", "FUNCTION": "Has a role in non-canonical Wnt/planar cell polarity (PCP) signaling; can recruit dvl/dsh and prickle from the cytoplasm to the plasma membrane, Acts in a PCP complex to regulate the polarized assembly of fibronectrin on the surface of the mesoderm during gastrulation, Regulates convergent extension cell movements in both dorsal mesoderm and neural tissue during gastrulation, without affecting cell fate, Regulates neural fold closure during neurulation (PubMed:11867525, PubMed:11780127, PubMed:12421719), May be required for cell surface localization of fzd3 and fzd6 in the inner ear (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Vang family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDNDSQYSGYSYKSGHSRSSRKHRDRRERHRSKSREGSRGDKSVTIQAPGEPLLDNESTRGEDRDDNWGETTTVVTGTSEHSISHDDITRITKDMEDSAKLDCSRHLGVVIGGALALLSFLTPIAFMLLPQILWREDLEQCGTACEGLFISVAFKLLILLLGSWALFFRRPKAFFPRVFVFRALLMVLVFLLVVSYWLFYGVRILESRDKNYQGIVQYAVSLVDALLFVHYLAVVLLELRQLQPQFTIKVVRSTDGASRFYNIGHLSIQRVAVWILENYYHDFPVYNPALLNLPKSILSKKMSGFKVYSLGEENTTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRKARLVVAVEEAFTHIKRLQDEDQKNPREIMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILHHLEFCITHDMTPKAFLERYLGPGPTIQYHKDRWLAKQWTLVSEEPVTNGLKDGVVFVLKRQDFSLVVSTKKIPFFKLSEEFVDPKSHKFVMRLQSETSV", "length": 521, "molWeight": 60097, "crc64": "49D0BC3EDADB77DA", "md5": "9C660BCFE3BBF553FD2FC229A3B39A12"}}
{"primaryAccession": "Q90YK5", "text": "This is Heparanase protein, from Chicken, contains 523 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q90YK5", "organism_name": "Chicken", "protein_name": "Heparanase", "length": 523, "firstPublicDate": "2005-10-11", "FUNCTION": "Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans, Participates in extracellular matrix (ECM) degradation and remodeling, Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group, Can also cleave the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying a 2-O-sulfo group, but not linkages between a glucuronic acid unit and a 2-O-sulfated iduronic acid moiety (By similarity), Increases cell adhesion to the extracellular matrix (ECM), independent of its enzymatic activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 79 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLVLLLLVLLLAVPPRRTAELQLGLREPIGAVSPAFLSLTLDASLARDPRFVALLRHPKLHTLASGLSPGFLRFGGTSTDFLIFNPNKDSTWEEKVLSEFQAKDVCEAWPSFAVVPKLLLTQWPLQEKLLLAEHSWKKHKNTTITRSTLDILHTFASSSGFRLVFGLNALLRRAGLQWDSSNAKQLLGYCAQRSYNISWELGNEPNSFRKKSGICIDGFQLGRDFVHLRQLLSQHPLYRHAELYGLDVGQPRKHTQHLLRSFMKSGGKAIDSVTWHHYYVNGRSATREDFLSPEVLDSFATAIHDVLGIVEATVPGKKVWLGETGSAYGGGAPQLSNTYVAGFMWLDKLGLAARRGIDVVMRQVSFGAGSYHLVDAGFKPLPDYWLSLLYKRLVGTRVLQASVEQADARRPRVYLHCTNPRHPKYREGDVTLFALNLSNVTQSLQLPKQLWSKSVDQYLLLPHGKDSILSREVQLNGRLLQMVDDETLPALHEMALAPGSTLGLPAFSYGFYVIRNAKAIACI", "length": 523, "molWeight": 58386, "crc64": "8EB0B7B18C9BF881", "md5": "06097725529D62AFA4BBEB7919271DEA"}}
{"primaryAccession": "Q91620", "text": "This is Nodal homolog 2-A protein, from African clawed frog, contains 405 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91620", "organism_name": "African clawed frog", "protein_name": "Nodal homolog 2-A", "length": 405, "firstPublicDate": "2007-02-06", "FUNCTION": "Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos, Essential for mesoderm formation and axial patterning during embryonic development, Activates the activin-like signaling pathway to induce dorsal and ventral mesoderm in animal cap ectoderm, In addition, also dorsalizes ventral marginal zone (VMZ) tissues during gastrulation, Induces muscle actin, Appears to act as both a short-range and long-range morphogen, The unprocessed protein inhibits bmp- and wnt-signaling", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the TGF-beta family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASLGVILFFVIASLIHGKPIHSERKAAKIPLEGSNLGYKKPNNIYGSRLSQGMRYPPSMMQLYQTLILGNDTDLSILEYPVLQESDAVLSLIAKSCVVVGNRWTLSFDMSSISSSNELKLAELRIRLPSFERSQDVTVEIYHTKEGQENLFMGSFKTNPSVAMGSSWKIFNLTRMLQYYLHQGEPFTNVEYIEVKNMHERAKPHVIKRGVRAEVEEGLQRNKDNTPASSFPTERVVLVVFTRDKPTASHFGSPSLIHTVESSKYVMSENTVRVTDTRRPRRNQKTKNTIVMNTIPSRSVGKTLCRRVDMIVDFEKIEWGDRIVYPKRFNAYRCEGACPIPLNETFKPTNHAYIKSLVKLYDQEKVECSSCVPVKMSPLSMLLYEDGEVVLKHHEDMIVDECGCN", "length": 405, "molWeight": 46067, "crc64": "8D852DF28AF23C88", "md5": "6311A7D2C2A71C214C1EEE6A1E45B9C4"}}
{"primaryAccession": "Q91821", "text": "This is Maternal embryonic leucine zipper kinase protein, from African clawed frog, contains 651 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91821", "organism_name": "African clawed frog", "protein_name": "Maternal embryonic leucine zipper kinase", "length": 651, "firstPublicDate": "2011-10-19", "FUNCTION": "Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation, Also plays a role in primitive hematopoiesis, possibly by affecting the expression of genes critical for hematopoiesis (By similarity), Plays a role in cytokinesis during early development", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAVDDYEELLKYYELHETVGTGGFAKVKLASHLITGEKVAIKIMDKESLGDDLPRVKTEIDAMKNLSHQHVCRLYHVIETPKKIFMVLEYCPGGELFDYIIAKDRLTEEEARVFFRQIVSAVAYIHSQGYAHRDLKPENLLIDEDQNLKLIDFGLCAKPKGGLDYHLMTCCGSPAYAAPELIQGKAYIGSEADIWSMGVLMYALMCGYLPFDDDNVMVLYKKIMRGKYEIPKWLSPGSVLLLSQMMQVDPKKRITVKHLLNHPWLMHGYSCPVEWQSKYPLGYIDEDCVTELSVFYKYSRTSTTRLISEWSYDHITASYLLLHSKKSHGKAVRLKHPLAVGDQAVTSFKELRPKSKLDFEEPNGEIAYVFGSMDFSDEELFSEDFTYSSFEPHTPKEYVKGRLEFNSVDSAPATPVVQRNARHKNEDKENSNTAVARDENVFLHPAPWTPTPRRKQNEKKGILTTPNKNTQTKEKNQSKETPTKKPIGTGEEFANVISPERRCRSVELDLNQAHIDSAQKKKGAKVFGSLERGLDKMITMLTPSKRKGYTREGPRKLRAHYNVTTTNIVNPEQLLNQIVRVLPSKNVDYVQKGYTLKCKTQSDFGKVTMQFELEVCQLSKSEVVGIRRQRLKGDAWVYKRLVEDILSSCKV", "length": 651, "molWeight": 74307, "crc64": "A21B397D0F1A9C9A", "md5": "5A66A4DC9A7427A6A524080C777713FA"}}
{"primaryAccession": "Q91876", "text": "This is DNA replication licensing factor mcm7-A protein, from African clawed frog, contains 720 amino acids, has 1 C4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [183, 210], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "Q91876", "organism_name": "African clawed frog", "protein_name": "DNA replication licensing factor mcm7-A", "length": 720, "firstPublicDate": "1997-11-01", "FUNCTION": "Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells, The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit, The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity, The existence of maternal and zygotic forms of mcm3 and mcm6 suggests that specific forms of mcm2-7 complexes may be used during different stages of development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCM family", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPRDYQTEKEKCKTFLQEFYKDDEIGKKHFKYGVQLANIAHREQVALYIDLDDLAEEDPELVDAICENTRRYTNLFADAVQELLPQYKEREVVHKDALDVYIEHRLMMEQRGRDPNEMRDSQNQYPPELMRRFELYFKAPSSSKARVVRDVKADSIGKLVNIRGIVTRVTEVKPMMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSRECQTNRSGGRLYLQTRGSKFIKFQELKIQEHSDQVPVGNIPRCMSVYVRGENTRLAQPGDHVGITGVFLPMLRTGFRQVVQGLLSETYLECHRLVKMNKSEDDELGTEELSEEELRQITEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDNSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVMKDPVTGEMTLEGGALVLADQGVCCIDEFDKMMDTDRTAIHEVMEQQTISIAKAGIMTTLNARCSILAAANPAYGRYNPKKTVEQNIQLPAALLSRFDVLWLIQDKPDRDNDLRLAQHITYVHQHSKQPPSQFQPLDMKLMRRYITMCKRKQPAIPEALADYLTAAYVEMRKEARTNKDMTFTSARTLLSVLRLSTALARLRLEDVVEKEDVNEAMRLMEMSKDSLLGDKGHTSRTQRPADVIFSTIREMVPEKGARSVKYSEAEQRCVSKGFTPAQFEAALEEYEELNVWLVNQARTKITFV", "length": 720, "molWeight": 81879, "crc64": "AD623D73B501647E", "md5": "885ED2F6D2D4C7A9302F49F0041235EE"}}
{"primaryAccession": "Q91V79", "text": "This is Fat storage-inducing transmembrane protein 1 protein, from Mouse, contains 292 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91V79", "organism_name": "Mouse", "protein_name": "Fat storage-inducing transmembrane protein 1", "length": 292, "firstPublicDate": "2008-02-26", "FUNCTION": "Plays an important role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (PubMed:18160536, PubMed:22106267) (By similarity), Directly binds to diacylglycerol (DAGs) and triacylglycerol (PubMed:22106267) (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the FIT family, FIT1 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MERGPTVGAGLGAGTRVRALLGCLVKVLLWVASALLYFGSEQAARLLGSPCLRRLYHAWLAAVVIFGPLLQFHVNSRTIFASHGNFFNIKFVNSAWGWTCTFLGGFVLLVVFLATRRVAVTARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLPQGLLLHELPDRKSCLAAGHQWRGYTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAPLRLVFLLNVLLLGLWNFLLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQPWSPGIPGHGLFPRSRSMRKHN", "length": 292, "molWeight": 32280, "crc64": "786133E48C9B227A", "md5": "E96FCA35E4CEC0C6F6A5033BDA5283BB"}}
{"primaryAccession": "Q91V88", "text": "This is Nephronectin protein, from Mouse, contains 561 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91V88", "organism_name": "Mouse", "protein_name": "Nephronectin", "length": 561, "firstPublicDate": "2007-07-24", "FUNCTION": "Functional ligand of integrin alpha-8/beta-1 in kidney development, Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development, May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the nephronectin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAVLLAAVLASSLYLQVAADFDGRWPRQIVSSIGLCRYGGRIDCCWGWARQSWGQCQPVCQPQCKHGECVGPNKCKCHPGFAGKTCNQDLNECGLKPRPCKHRCMNTFGSYKCYCLNGYMLLPDGSCSSALSCSMANCQYGCDVVKGQVRCQCPSPGLQLAPDGRTCVDIDECATGRVSCPRFRQCVNTFGSYICKCHTGFDLMYIGGKYQCHDIDECSLGQHQCSSYARCYNIHGSYKCQCRDGYEGDGLNCVYIPKVMIEPSGPIHMPERNGTISKGDGGHANRIPDAGSTRWPLKTPYIPPVITNRPTSKPTTRPTPNPTPQPTPPPPPPLPTEPRTTPLPPTPERPSTRPTTIAPATSTTTRVITVDNRIQTDPQKPRGDVFIPRQPTNDLFEIFEIERGVSADEEVKDDPGILIHSCNFDHGLCGWIREKDSDLHWETARDPAGGQYLTVSAAKAPGGKAARLVLRLGHLMHSGDLCLSFRHKVTGLHSGTLQVFVRKHGTHGAALWGRNGGHGWRQTQITLRGADVKSVIFKGEKRRGHTGEIGLDDVSLKRGRC", "length": 561, "molWeight": 61490, "crc64": "69E7ACAA0EE3F506", "md5": "CBC3F91BC7524938B0264BAB8B5047FB"}}
{"primaryAccession": "Q91WC0", "text": "This is Actin-histidine N-methyltransferase protein, from Mouse, contains 594 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91WC0", "organism_name": "Mouse", "protein_name": "Actin-histidine N-methyltransferase", "length": 594, "firstPublicDate": "2006-10-31", "FUNCTION": "Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73' (PubMed:30626964), Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PubMed:30626964), Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (PubMed:30626964)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the class V-like SAM-binding methyltransferase superfamily, SETD3 actin-histidine methyltransferase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPSPGKEWEEYTQIRALVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEEEVRCLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKESFTYEDYRWAVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFQAGDQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHSTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNAEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKIVLKNPDLSVRATMAIKLRLGEKEILEKAVKSAAVNREYYRKHMEERAPLPRYEESDLGLLEGGVGDSRLPLVLRKLEEEAGVQESLSLTETVSKVKAAENGLVNGENLIPNGTRSENESLSPEESENVTGEESSGSMAKVKERL", "length": 594, "molWeight": 67176, "crc64": "67DA47889A5C9F55", "md5": "85E50405139808C8043E9328F2A726C5"}}
{"primaryAccession": "Q91XJ0", "text": "This is Calcium-responsive transcription coactivator protein, from Rat, contains 401 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91XJ0", "organism_name": "Rat", "protein_name": "Calcium-responsive transcription coactivator", "length": 401, "firstPublicDate": "2010-02-09", "FUNCTION": "Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons, Recruits CREB-binding protein (CREBBP) to nuclear bodies, Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex, In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex, Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex, At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation, The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SS18 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILDYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNMNLGPGALSQSGSSQGLHPQGSLSDTVSTGLPPASLMQGQIGNGPNHVSMQQTAQSTLPTTSMSMSGSGHGTGPGYSHSGPTSQSVPMQGQGAISNYVSRTNINMQSNPVSMMHQQAARPTTTQRRVEASITRARRPLHDGPGWQGGSMMGQRPMAPYRPSQQGSSQQYLGQEEYYSEQYSHSQGSAEPMSQQYYPDGHSDYAYQQSSYTEQSYDRSFEDPTQHYYEGGNSQYSQQQAGYQQGTAQQQTYSQQQYPNQQSYPGQQQGYGPAQGAPSQYSGYQQGQGQQYGSYRTSQTGPSAQQQRPYGYEQGQYGNYQQ", "length": 401, "molWeight": 43999, "crc64": "2B1805EC74EEC12F", "md5": "10F0B087DE488B459B6CE5959DF21A99"}}
{"primaryAccession": "Q91YR1", "text": "This is Twinfilin-1 protein, from Mouse, contains 350 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91YR1", "organism_name": "Mouse", "protein_name": "Twinfilin-1", "length": 350, "firstPublicDate": "2004-02-02", "FUNCTION": "Actin-binding protein involved in motile and morphological processes, Inhibits actin polymerization, likely by sequestering G-actin, By capping the barbed ends of filaments, it also regulates motility, Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the actin-binding proteins ADF family, Twinfilin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVVGSCSPPSDSWEQDYDSFVLPLLEDKQPCYVLFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDEVFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINEVQTDVSVDTKHQTLQGVAFPISRDAFQALEKLSKKQLNYVQLEIDIKNETIILANTENTELRDLPKRIPKDSARYHFFLYKHSHEGDYLESVVFIYSMPGYTCSIRERMLYSSCKSPLLEIVERQLQMDVIRKIEIDNGDELTADFLYDEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAEAEATTD", "length": 350, "molWeight": 40079, "crc64": "643CBBA18D38D4E0", "md5": "690BA26EC77951F8EFFA0ECA6D4B65E4"}}
{"primaryAccession": "Q91ZD4", "text": "This is Vang-like protein 2 protein, from Mouse, contains 521 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91ZD4", "organism_name": "Mouse", "protein_name": "Vang-like protein 2", "length": 521, "firstPublicDate": "2003-10-31", "FUNCTION": "Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate, Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea, Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process, Required for cell surface localization of FZD3 and FZD6 in the inner ear (PubMed:16495441)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Vang family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDTESQYSGYSYKSGHSRSSRKHRDRRDRHRSKSRDGSRGDKSVTIQAPGEPLLDNESTRGDERDDNWGETTTVVTGTSEHSISHDDLTRIAKDMEDSVPLDCSRHLGVAAGAILALLSFLTPLAFLLLPPLLWREELEPCGTACEGLFISVAFKLLILLLGSWALFFRRPKASLPRVFVLRALLMVLVFLLVISYWLFYGVRILDARERSYQGVVQFAVSLVDALLFVHYLAVVLLELRQLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLAKKVSGFKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRRARLVVAVEEAFTHIKRLQEEEQKNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLAAGPTIQYHKERWLAKQWTLVSEEPVTNGLKDGIVFLLKRQDFSLVVSTKKVPFFKLSEEFVDPKSHKFVMRLQSETSV", "length": 521, "molWeight": 59771, "crc64": "94ECEF3EE63DF5BC", "md5": "2D561067D868AC19D65660D5063A882E"}}
{"primaryAccession": "Q92484", "text": "This is Acid sphingomyelinase-like phosphodiesterase 3a protein, from Human, contains 453 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q92484", "organism_name": "Human", "protein_name": "Acid sphingomyelinase-like phosphodiesterase 3a", "length": 453, "firstPublicDate": "2001-08-29", "FUNCTION": "Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:25288789, PubMed:26783088), Has in vitro activity with p-nitrophenyl-TMP (PubMed:25288789), Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (PubMed:25288789, PubMed:26783088), Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine, Has in vitro activity with CDP-ethanolamine (PubMed:26783088), Does not have sphingomyelin phosphodiesterase activity (PubMed:25288789, PubMed:26783088)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the acid sphingomyelinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALVRALVCCLLTAWHCRSGLGLPVAPAGGRNPPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAIMNLDNISYADCLKQLYIKHNY", "length": 453, "molWeight": 51260, "crc64": "2EFE762BF663984B", "md5": "0D9AD5FF7570194760F877CED6870DB8"}}
{"primaryAccession": "Q92506", "text": "This is (3R)-3-hydroxyacyl-CoA dehydrogenase protein, from Human, contains 261 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q92506", "organism_name": "Human", "protein_name": "(3R)-3-hydroxyacyl-CoA dehydrogenase", "length": 261, "firstPublicDate": "2000-05-30", "FUNCTION": "Required for the solubility and assembly of the heterotetramer 3-ketoacyl-[acyl carrier protein] (ACP) reductase functional complex (KAR or KAR1) that forms part of the mitochondrial fatty acid synthase (mtFAS), Alpha-subunit of the KAR complex that acts as a scaffold protein required for the stability of carbonyl reductase type-4 (CBR4, beta-subunit of the KAR complex) and for its 3-ketoacyl-ACP reductase activity, thereby participating in mitochondrial fatty acid biosynthesis, Catalyzes the NAD-dependent conversion of (3R)-3-hydroxyacyl-CoA into 3-ketoacyl-CoA (3-oxoacyl-CoA) with no chain length preference; this enzymatic activity is not needed for the KAR function (PubMed:19571038, PubMed:25203508, PubMed:30508570), Prefers (3R)-3-hydroxyacyl-CoA over (3S)-3-hydroxyacyl-CoA and displays enzymatic activity only in the presence of NAD(+) (PubMed:19571038), Cooperates with enoyl-CoA hydratase 1 in mitochondria, together they constitute an alternative route to the auxiliary enzyme pathways for the breakdown of Z-PUFA (cis polyunsaturated fatty acid) enoyl-esters (Probable) (PubMed:30508570), NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol (17beta-estradiol or E2), Has very low activity towards testosterone and dihydrotestosterone (17beta-hydroxy-5alpha-androstan-3-one), Primarily an oxidative enzyme, it can switch to a reductive mode determined in the appropriate physiologic milieu and catalyze the reduction of estrone (E1) to form biologically active 17beta-estradiol (PubMed:17978863)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the short-chain dehydrogenases/reductases (SDR) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM", "length": 261, "molWeight": 26974, "crc64": "8B8B2D7131714D71", "md5": "A6C7935675941058EFCC413220BA7571"}}
{"primaryAccession": "Q92521", "text": "This is GPI mannosyltransferase 3 protein, from Human, contains 554 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q92521", "organism_name": "Human", "protein_name": "GPI mannosyltransferase 3", "length": 554, "firstPublicDate": "2006-07-25", "FUNCTION": "Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis, Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyltransferase 22 family, PIGB subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRRPLSKCGMEPGGGDASLTLHGLQNRSHGKIKLRKRKSTLYFNTQEKSARRRGDLLGENIYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVFYLNPLNWLHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHTHLPEGRIGSHIYVYERKLKGKFNMKMKF", "length": 554, "molWeight": 65056, "crc64": "B2AF87D13ADF90B3", "md5": "EDD5F15382134A92398F00A386622F61"}}
{"primaryAccession": "Q92643", "text": "This is GPI-anchor transamidase protein, from Human, contains 395 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q92643", "organism_name": "Human", "protein_name": "GPI-anchor transamidase", "length": 395, "firstPublicDate": "2002-07-11", "FUNCTION": "Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI, During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the peptidase C13 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQMDEKLMEPLKYAEQLPVAQIIHQKPKLKDWHPPGGFILGLWALIIMVFFKTYGIKHMKFIF", "length": 395, "molWeight": 45252, "crc64": "AF706DDDAD13EFB2", "md5": "4D760327BF99F62E80DCABC6AD2F47F0"}}
{"primaryAccession": "Q92754", "text": "This is Transcription factor AP-2 gamma protein, from Human, contains 450 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q92754", "organism_name": "Human", "protein_name": "Transcription factor AP-2 gamma", "length": 450, "firstPublicDate": "2001-01-24", "FUNCTION": "Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes, AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development, They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC, Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the AP-2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLWKITDNVKYEEDCEDRHDGSSNGNPRVPHLSSAGQHLYSPAPPLSHTGVAEYQPPPYFPPPYQQLAYSQSADPYSHLGEAYAAAINPLHQPAPTGSQQQAWPGRQSQEGAGLPSHHGRPAGLLPHLSGLEAGAVSARRDAYRRSDLLLPHAHALDAAGLAENLGLHDMPHQMDEVQNVDDQHLLLHDQTVIRKGPISMTKNPLNLPCQKELVGAVMNPTEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAHVTLLTSLVEGEAVHLARDFAYVCEAEFPSKPVAEYLTRPHLGGRNEMAARKNMLLAAQQLCKEFTELLSQDRTPHGTSRLAPVLETNIQNCLSHFSLITHGFGSQAICAAVSALQNYIKEALIVIDKSYMNPGDQSPADSNKTLEKMEKHRK", "length": 450, "molWeight": 49177, "crc64": "2D4F5FBC269A34A8", "md5": "E43EF512684D08B17ACFFD44DBCAB8EF"}}
{"primaryAccession": "Q92791", "text": "This is Endoplasmic reticulum protein SC65 protein, from Human, contains 437 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q92791", "organism_name": "Human", "protein_name": "Endoplasmic reticulum protein SC65", "length": 437, "firstPublicDate": "1998-07-15", "FUNCTION": "Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils, Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the leprecan family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MARVAWGLLWLLLGSAGAQYEKYSFRGFPPEDLMPLAAAYGHALEQYEGESWRESARYLEAALRLHRLLRDSEAFCHANCSGPAPAAKPDPDGGRADEWACELRLFGRVLERAACLRRCKRTLPAFQVPYPPRQLLRDFQSRLPYQYLHYALFKANRLEKAVAAAYTFLQRNPKHELTAKYLNYYQGMLDVADESLTDLEAQPYEAVFLRAVKLYNSGDFRSSTEDMERALSEYLAVFARCLAGCEGAHEQVDFKDFYPAIADLFAESLQCKVDCEANLTPNVGGYFVDKFVATMYHYLQFAYYKLNDVRQAARSAASYMLFDPKDSVMQQNLVYYRFHRARWGLEEEDFQPREEAMLYHNQTAELRELLEFTHMYLQSDDEMELEETEPPLEPEDALSDAEFEGEGDYEEGMYADWWQEPDAKGDEAEAEPEPELA", "length": 437, "molWeight": 50381, "crc64": "50C82FCE9BB7274A", "md5": "C9C88009AC38C0B9B444FD188CCB78B3"}}
{"primaryAccession": "Q93373", "text": "This is Leucine-rich repeat-containing protein let-4 protein, from Caenorhabditis elegans, contains 773 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q93373", "organism_name": "Caenorhabditis elegans", "protein_name": "Leucine-rich repeat-containing protein let-4", "length": 773, "firstPublicDate": "2013-05-29", "FUNCTION": "Required for apical extracellular matrix organization and epithelial junction maintenance", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRLLLCLLLFSTLLINSTNACPGVITQACFCSEVHSGIVLDCSNSSASGILQIIRTNQAQVGLIQSLTMNQAELVELPPNFFSGLFIRRLDLSQNKIKKIDDAAFAGINPVLEEVVLNHNLIEKVPAAALAGLPNLLRLDLSNNSIVEIQEQEIFPNLNKLYDINLGSNKIFSIHTSTFQNVKNSIQTINLGHNNMTAVPSSAIRGLKQLQSLHLHKNRIEQLDALNFLNLPVLNLLNLAGNQIHELNRQAFLNVPSLRYLYLSGNKITKLTAYQFQTFEQLEMLDLTNNEIGAIPANSLSGLKQLRQLYLAHNKISNISSNAFTNSSIVVLVLSSNELKTLTAGIISGLPNLQQVSFRDNQIKTINRNAFYDAASLVMLDLAKNQLTEIAPTTFLAQLNLLLVDLSENKLPKTPYSAFNSRVGTVLLKENPLVCTENLHMLQQGTGVYVRDSPDIICGRKPTPKPEPVLVPIVTDSLISTQRPALVQIPKMQIHRNVHTTTGDQAPQIPSGAFQQIDLGKSRSLPRGHSRFILDKPSTREQSVEPTEELTPIQPIILPSREDEIRQSSMEAGTSQESVEATSQKIPSTTDIIDRPNVVLPFPVPFLKRGPNLSESKKVESTDMPSTSQVFHTLPPSILIEPGSTPKVAQPSTEANIKSEHIDEFALASSNSNEPTLQPRLEKSFFTTTIIFICVGTAVIVLVVVIAGLCISKHRQLQFENTYSDSSAARTSEYISTQYRQNSLRGTGGRVGRFEESPAWIYNPGSSYCNYYK", "length": 773, "molWeight": 85297, "crc64": "5B1CF58516E91F78", "md5": "1B253BFC9AFA8C0FC69FB22DD3C8D566"}}
{"primaryAccession": "Q93833", "text": "This is Intraflagellar transport protein che-13 protein, from Caenorhabditis elegans, contains 412 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q93833", "organism_name": "Caenorhabditis elegans", "protein_name": "Intraflagellar transport protein che-13", "length": 412, "firstPublicDate": "2008-04-08", "FUNCTION": "Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium (PubMed:12651157, PubMed:28479320), May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility (PubMed:28479320), Required for the formation of chemosensory cilia that detect chemosensory cues (PubMed:12651157)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the IFT57 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEEEHEEESHLSQSDTVGSAIVEDGPGKEYEIYIKNEELVDKLKLLNYEDGFLKLGVVYKPILKHYFVKSKNVGEQFFLFTSLAAWLIKKSGDESYNMPQEFDDPNSTLANIMAAAKNKGIATDFTAAKLKSGAGENVIFILNSLADASLVHVGFQWQKMIPPKEEDEDTAVDEQDEDDDNDDIVEEPMNFLDDDDDDNVIEIDLKAQGLATESKNPLQSVLQSNTDAITWKQEVERVAPQLKITLKQDAKDWRLHLEQMNSMHKNVEQKVGNVGPYLDNMSKDIAKALERIASREKSLNSQLASMMSKFRRATDTRAELREKYKAASVGVSSRTETLDRISDDIEQLKQQIEEQGAKSSDGAPLVKIKQAVSKLEEELQTMNVQIGVFEQSILNTYLRDHFNFSANLLNIM", "length": 412, "molWeight": 46504, "crc64": "715BA9E68C14A446", "md5": "E38A5B02C8543BBFDCEB902C9509A3C5"}}
{"primaryAccession": "Q93VJ2", "text": "This is Serine/threonine-protein kinase/endoribonuclease IRE1b protein, from Mouse-ear cress, contains 881 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q93VJ2", "organism_name": "Mouse-ear cress", "protein_name": "Serine/threonine-protein kinase/endoribonuclease IRE1b", "length": 881, "firstPublicDate": "2013-05-01", "FUNCTION": "Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation, The active endoribonuclease domain splices bZIP60 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator which then induces transcription of UPR target genes, Involved in organ growth regulation, Plays a role in plant immunity and abiotic stress responses, Required for ER stress-induced autophagy", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRGSALLDLILFLLVSPLAHSFKGSEISKFYDKSISNQISQSDRESGYVLVSTVDGSISLVDMSSQKLDWTFHTNEPIYSSYQAPHYHYTTDEERSSVLGDDFYMDCDKDWRLYNSSVRKGKRVNEIVDASEFIGTLPYTSTDRIVLGKKDTSVFLLDWKTGKLVKRYRMDELYSNTVVENDKEKAIVLSKEAPLLFGSGFKKSEDFPELVYIERKDFKIQCISKFGDVLWSVSYAKMEAKLQNHESVQFISGLSSSVGKNQFPLSYTTSVPMVQLRNVKYETLFPRLGFLDEALYLPFQDRKPNQLAIGDGNQLTLPGNKEAEEVLSLPLPETVISQITDIIDGSTKQAGFASKFSGLIVLIFGFCVTMLSVCGLFFYRLRQSIRIKEPYVSEVPIATPKKKKSKKNGTTKAVHKKENGFISGGNKDPSHEENEKRLLTAFPGLNNSSAEGYRVGKLFVSNKEIAKGSNGTVVLEGSYEGRLVAVKRLVQSHHDVAQKEILNLMASDKHSNIVRWYGVDQDEHFIYISLELCACSLNDLIYASSALLESPMASSSIHSIQINPIFENGKGVELWKENGHPSPVLLKLMRDIVAGLVHLHDIGIVHRDLKPQNVLIVKNSSLCAKLSDMGISKRLPADTSALTRNSTGLGSGSSGWQAPEQLRNERQTRAVDLFSLGCVLFFCMTGGKHPYGDNYERDVNVLNDQKDLFLIESLPEAVHLLTGLLNPDPNLRPRAQDVMHHPLFWNSDMRLSFLRDASDRVELENREEGSQLLAALESTAAVTLNGRWDEKLDSIFLDNIGRYRRYKFDSIRDLLRVIRNKLNHYRELPKELQELLGSVPEGFERYFSSRFPKLLIQVYTVLFDYCNNEEFFFKYSKTTVF", "length": 881, "molWeight": 99616, "crc64": "AECD3585336081F8", "md5": "4C58D2ADC7E6FCFE39670E280E7B0B8C"}}
{"primaryAccession": "Q93VQ0", "text": "This is Protein VACUOLELESS1 protein, from Mouse-ear cress, contains 858 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q93VQ0", "organism_name": "Mouse-ear cress", "protein_name": "Protein VACUOLELESS1", "length": 858, "firstPublicDate": "2014-03-19", "FUNCTION": "Required for vacuole biogenesis and vacuole enlargment in dividing and expanding cells, Involved in the docking or fusion of prevacuolar vesicles, Important for the function of both male and female gametophytes, but is not essential for the germination and development of pollen", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the VPS16 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MANVSVAAEWQLLYDRYYRKPEIYQMKWKHVDLSRNKVACASFGGPIAVIRDDSKIVQLYAESALRKLRIFNSAGILLSETVWKHPGGRLIGMSWSDDQTLICIVQDGTIYRYNIHAELIEPNMSMGQECFEQNVVECVFWGNGVVCLTEGGQLICIFDFKTMKPSKLPDVPGLAEDDLLQPICLTVREPKYTMSGIAEVLVAVGDDIFVVEEDMVQTIRFDEPSVDDSEMQNDDSGNLIGVVQKMIVSPNGKFLTLFTHDGRIVVVDMETKQIAIDYSCESALPPQQMAWCGMDSVLLYWDEDLMMVGPVGDPVHYFYDEPIILIPECDGVRILSNTNLEFLQRVPDSTESIFKIGSTSPAALLYDALDHFDRRSAKADENLRLIRSSLSEAVESCIDAAGHEFDVTRQRALLRAASYGQAFCSNFQRERVQETCRTLRVLNAVRDPAIGIPLSIQQYKLLTPVVLISRLINANCHLLALRISEYLDMNKEVVIMHWACAKITASPSTPDSHLLEILLDKLQLCKGISYAAVATHADNCGRRKLAAMLVEHEPRSTKQVPLLLSIGEEDTALVKATESGDTDLVYLVIFHIWQKRPPLEFFAMIQGRVLARDLFVAYARCHKHEFLKDFFLSTGQIHEVAFLLWKESWDMGKNPMASKGSPLHGPRIKLIEKARNLFSQTKEHTFESKAAEEHAKLLKIQHELEASTKQAIFVDSSINDTIRTCIVLGNNRAAIKVKTEFKVSDKRWYWLKAFALATIKDWAALEKFSKEKRPPMGFRPFVEACIDADEKAEALKYIPKLSDLVERGEAYARIGMAKEAADCAAQANDGGELLERFRKTFVQNAIFDTLLMPFQGAS", "length": 858, "molWeight": 96632, "crc64": "94D8658581CA7023", "md5": "E925818B099E1E0A1982FAAC1CDF358E"}}
{"primaryAccession": "Q93VY3", "text": "This is NAC domain-containing protein 72 protein, from Mouse-ear cress, contains 297 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q93VY3", "organism_name": "Mouse-ear cress", "protein_name": "NAC domain-containing protein 72", "length": 297, "firstPublicDate": "2009-05-26", "FUNCTION": "Transcription factors that bind specifically to the 5'-CATGTG-3' motif and with bipartite regions with 5'-CGTr-3' and 5'-YACG-3' as cores (PubMed:15319476, PubMed:29659022), Involved in the regulation of metabolic reprogramming during senescence by promoting the chloroplast protein degradation and the catabolism of lysine, phytol and free fatty acids via the induction of CV, LKR/SDH and PES1 expression (PubMed:29659022), Triggers also the degradation of starch and the accumulation of mono- and disaccharides during senescence by enhancing the expression of AMY1, SFP1 and SWEET15 (PubMed:29659022)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGVREKDPLAQLSLPPGFRFYPTDEELLVQYLCRKVAGYHFSLQVIGDIDLYKFDPWDLPSKALFGEKEWYFFSPRDRKYPNGSRPNRVAGSGYWKATGTDKIITADGRRVGIKKALVFYAGKAPKGTKTNWIMHEYRLIEHSRSHGSSKLDDWVLCRIYKKTSGSQRQAVTPVQACREEHSTNGSSSSSSSQLDDVLDSFPEIKDQSFNLPRMNSLRTILNGNFDWASLAGLNPIPELAPTNGLPSYGGYDAFRAAEGEAESGHVNRQQNSSGLTQSFGYSSSGFGVSGQTFEFRQ", "length": 297, "molWeight": 33177, "crc64": "7618A68331407370", "md5": "ABDF14E03DD429B8EC6C3A7153846C4D"}}
{"primaryAccession": "Q93WX6", "text": "This is Cysteine desulfurase 1, chloroplastic protein, from Mouse-ear cress, contains 463 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q93WX6", "organism_name": "Mouse-ear cress", "protein_name": "Cysteine desulfurase 1, chloroplastic", "length": 463, "firstPublicDate": "2006-10-03", "FUNCTION": "Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine (PubMed:12033984, PubMed:16455656), Supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters (PubMed:15480755, PubMed:17372218), Required for the maturation of all plastidic Fe-S proteins and, thus, essential for plant growth (PubMed:17372218)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEGVAMKLPSFPNAISIGHRSFSRVRCSSSLSVCSAAAASSATISTDSESVSLGHRVRKDFRILHQEVNGSKLVYLDSAATSQKPAAVLDALQNYYEFYNSNVHRGIHYLSAKATDEFELARKKVARFINASDSREIVFTRNATEAINLVAYSWGLSNLKPGDEVILTVAEHHSCIVPWQIVSQKTGAVLKFVTLNEDEVPDINKLRELISPKTKLVAVHHVSNVLASSLPIEEIVVWAHDVGAKVLVDACQSVPHMVVDVQKLNADFLVASSHKMCGPTGIGFLYGKSDLLHSMPPFLGGGEMISDVFLDHSTYAEPPSRFEAGTPAIGEAIALGAAVDYLSGIGMPKIHEYEVEIGKYLYEKLSSLPDVRIYGPRPSESVHRGALCSFNVEGLHPTDLATFLDQQHGVAIRSGHHCAQPLHRYLGVNASARASLYFYNTKDDVDAFIVALADTVSFFNSFK", "length": 463, "molWeight": 50485, "crc64": "7A00460377E01067", "md5": "8974A6B11D5E2C5953BC458023D6561D"}}
{"primaryAccession": "Q93YP7", "text": "This is 4-hydroxybenzoate polyprenyltransferase, mitochondrial protein, from Mouse-ear cress, contains 407 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q93YP7", "organism_name": "Mouse-ear cress", "protein_name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "length": 407, "firstPublicDate": "2011-03-08", "FUNCTION": "Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group, Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate, Required for embryo development", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the UbiA prenyltransferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFFGLSRVSRRLLKSSVSVTPSSSSALLQSQHKSLSNPVTTHYTNPFTKCYPSWNDNYQVWSKGRELHQEKFFGVGWNYRLICGMSSSSSVLEGKPKKDDKEKSDGVVVKEASWIDLYLPEEVRGYAKLARLDKPIGTWLLAWPCMWSIALAADPGSLPSFKYMALFGCGALLLRGAGCTINDLLDQDIDTKVDRTKLRPIASGLLTPFQGIGFLGLQLLLGLGILLQLNNYSRVLGASSLLLVFSYPLMKRFTFWPQAFLGLTINWGALLGWTAVKGSIAPSIVLPLYLSGVCWTLVYDTIYAHQDKEDDVKVGVKSTALRFGDNTKLWLTGFGTASIGFLALSGFSADLGWQYYASLAAASGQLGWQIGTADLSSGADCSRKFVSNKWFGAIIFSGVVLGRSFQ", "length": 407, "molWeight": 44604, "crc64": "3A4E4941A1413A9C", "md5": "04A215C4DF0F0FD1677A379A553A7E22"}}
{"primaryAccession": "Q93ZM9", "text": "This is Protein TIFY 9 protein, from Mouse-ear cress, contains 197 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q93ZM9", "organism_name": "Mouse-ear cress", "protein_name": "Protein TIFY 9", "length": 197, "firstPublicDate": "2007-09-11", "FUNCTION": "Repressor of jasmonate (JA) responses (PubMed:19151223), Interacts with and suppresses RHD6 and RSL1 transcription factor activities to negatively regulate jasmonate-stimulated root hair development (PubMed:31988260)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TIFY/JAZ family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSKATIELDFLGLEKKQTNNAPKPKFQKFLDRRRSFRDIQGAISKIDPEIIKSLLASTGNNSDSSAKSRSVPSTPREDQPQIPISPVHASLARSSTELVSGTVPMTIFYNGSVSVFQVSRNKAGEIMKVANEAASKKDESSMETDLSVILPTTLRPKLFGQNLEGDLPIARRKSLQRFLEKRKERLVSTSPYYPTSA", "length": 197, "molWeight": 21813, "crc64": "475DADBCEDC540E1", "md5": "C25B17A6AE7FD88A9E93F5C2E524D767"}}
{"primaryAccession": "Q941F1", "text": "This is Phospholipase A1-Igamma1, chloroplastic protein, from Mouse-ear cress, contains 515 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q941F1", "organism_name": "Mouse-ear cress", "protein_name": "Phospholipase A1-Igamma1, chloroplastic", "length": 515, "firstPublicDate": "2010-10-05", "FUNCTION": "Acylhydrolase with a broad specificity, Catalyzes the hydrolysis of phosphatidylcholine at the sn-1 position, Moderate activity toward phosphatidylcholine (PC), monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG) and triacylglycerol (TAG), May display dual sn-1/sn-2 substrate specificity, Could be involved in early wound response", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATIPSHNLRPHTTNQRTQYSLSFRPHFSRSTLITFPARSSPARAMSRTDEEASISTRLEQESYGLTTAEDIRRRDGEAKESKRLRDTWRKIQGEDDWAGLMDPMDPVLRSELIRYGEMAQACYDAFDFDPFSRYCGSCRFTRRHLFDSLGIIDSGYEVARYLYATSNINLPNFFSKSRWSKVWSKNANWMGYVAVSDDNEATRCRLGRRDIAIAWRGTVTRLEWIADLKDFLKPVSGNGFRCPDPAVKAESGFLDLYTDKDTSCNFSKFSAREQVLTEVKRLVERYGDEEGEELSITVTGHSLGGALAVLSAYDVAEMGVNRTRKGKVIPVTAFTYGGPRVGNIRFKERIEKLGVKVLRVVNEHDVVAKSPGLFLNERAPQALMKLAGGLPWCYSHVGEMLPLDHQKSPFLKPTVDLSTAHNLEALLHLLDGYHGKGQRFVLSSGRDPALVNKASDFLKDHFMVPPYWRQDANKGMVRNTDGRWIQPDRIRADDQHAPDIHQLLTQLHHPSQLL", "length": 515, "molWeight": 58445, "crc64": "DD59442CB9166451", "md5": "863968F8170EAC235873D6834DBF2DF1"}}
{"primaryAccession": "Q945K7", "text": "This is Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial protein, from Mouse-ear cress, contains 374 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q945K7", "organism_name": "Mouse-ear cress", "protein_name": "Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial", "length": 374, "firstPublicDate": "2007-01-09", "FUNCTION": "Performs an essential role in the oxidative function of the citric acid cycle", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTMAANLARRLIGNRSTQILGAVNSSSGAASSVARAFCSSTTPITATLFPGDGIGPEIAESVKKVFTTAGVPIEWEEHYVGTEIDPRTQSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVDLITIRENTEGEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFLYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEITYEEVVIDNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLVGGLGLTPSCNIGEDGVALAEAVHGSAPDIAGKNLANPTALLLSGVMMLRHLKFNEQAEQIHSAIINTIAEGKYRTADLGGSSTTTEFTKAICDHL", "length": 374, "molWeight": 40625, "crc64": "723D0150C360F7A1", "md5": "E7F584AA97CA6EADF929CDC555A144AC"}}
{"primaryAccession": "Q946J8", "text": "This is Chromo domain-containing protein LHP1 protein, from Mouse-ear cress, contains 445 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q946J8", "organism_name": "Mouse-ear cress", "protein_name": "Chromo domain-containing protein LHP1", "length": 445, "firstPublicDate": "2006-07-25", "FUNCTION": "Structural component of heterochromatin involved in gene repression, including several floral homeotic genes and FLT that regulates flowering time (PubMed:9611176), Required for maintenance of vernalization-induced repression of FLC, As part of the PRC1-like complex, recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me), leading to epigenetic repression, PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development, PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility, Transcriptional repressor that binds DNA on GAGA-like motif and 5'-(A/G/T)AACCCTA(A/G)-3' consensus motif in the promoters of target genes, Recognizes and binds histone H3 tails methylated at 'Lys-27' (H3K27me) but depleted in active histone marks such as H3K4me, leading to epigenetic repression, When in complex with LHP1, recognizes and binds histone H3 tails methylated at 'Lys-4' (H3K4me) and 'Lys-27' (H3K27me), mostly corresponding to stress-responsive genes (PubMed:27495811)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKGASGAVKKKPQVLNEAGEAETAVETVGESRKISGDGGFGSDDGGGGGGGGSGESILREIGDDRPTEDGDEEEEEDEDEDDGGDEEDEEGEGEGGQEERPKLDEGFYEIEAIRRKRVRKGKVQYLIKWRGWPETANTWEPLENLQSIADVIDAFEGSLKPGKPGRKRKRKYAGPHSQMKKKQRLTSTSHDATEKSDSSTSLNNSSLPDIPDPLDLSGSSLLNRDVEAKNAYVSNQVEANSGSVGMARQVRLIDNEKEYDPTLNELRGPVNNSNGAGCSQGGGIGSEGDNVRPNGLLKVYPKELDKNSRFIGAKRRKSGSVKRFKQDGSTSNNHTAPTDQNLTPDLTTLDSFGRIARMGNEYPGVMENCNLSQKTKIEELDITKILKPMSFTASVSDNVQEVLVTFLALRSDGKEALVDNRFLKAHNPHLLIEFYEQHLKYNRTP", "length": 445, "molWeight": 48644, "crc64": "FE68BD510376D622", "md5": "BDBD714B0FF5D37740EC3E6471778A2E"}}
{"primaryAccession": "Q948R1", "text": "This is Phospholipase A(1) DAD1, chloroplastic protein, from Mouse-ear cress, contains 447 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q948R1", "organism_name": "Mouse-ear cress", "protein_name": "Phospholipase A(1) DAD1, chloroplastic", "length": 447, "firstPublicDate": "2010-10-05", "FUNCTION": "Sn-1-specific phospholipase that releases free fatty acids from phospholipids, Low activity on galactolipids and triacylglycerols, Catalyzes the initial step of jasmonic acid biosynthesis, Not essential for jasmonate biosynthesis after wounding or upon pathogen infection", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRFSLSPVRPHSVVVPSLPKQDVVSYISGTTSNRQCRCVLTLPSPSVSTSRPPVLPKPETWESLLLNHDQIPGEFSPTGSSIPVKLGRRWMEYQGLQNWDGLLDPLDDNLRREILRYGQFVESAYQAFDFDPSSPTYGTCRFPRSTLLERSGLPNSGYRLTKNLRATSGINLPRWIEKAPSWMATQSSWIGYVAVCQDKEEISRLGRRDVVISFRGTATCLEWLENLRATLTHLPNGPTGANLNGSNSGPMVESGFLSLYTSGVHSLRDMVREEIARLLQSYGDEPLSVTITGHSLGAAIATLAAYDIKTTFKRAPMVTVISFGGPRVGNRCFRKLLEKQGTKVLRIVNSDDVITKVPGVVLENREQDNVKMTASIMPSWIQRRVEETPWVYAEIGKELRLSSRDSPHLSSINVATCHELKTYLHLVDGFVSSTCPFRETARRVLHR", "length": 447, "molWeight": 49960, "crc64": "0EA3ABFD6545B5A1", "md5": "5B781D5B502481920CD0341CCD9AD790"}}
{"primaryAccession": "Q948T9", "text": "This is Respiratory burst oxidase homolog protein B protein, from Potato, contains 867 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q948T9", "organism_name": "Potato", "protein_name": "Respiratory burst oxidase homolog protein B", "length": 867, "firstPublicDate": "2008-01-15", "FUNCTION": "Calcium-dependent NADPH oxidase that generates superoxide, Involved in the massive phase II oxidative burst induced by pathogen infection", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the RBOH (TC 5,B,1,3) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEIENTRDSDSMRGSRVGFSGSLVSGKKSARFKDDESYVEITLDVRDDSVSVQNIKGADHEAALLASRLEKRPNNTLGSQLSFHLRQVSKELKRMTSSNKFQKIDRSKSGAARALRGLQFMNKNVGTEGWSEVESRFDQLAVNGMLTKSLFGQCIGMKESSEFAEELFDALARKRCITSPAVTKDELREFWEQITDTSFDARLQTFFDMVDKDADGRITQEEVKEIISLSASANKLSKIQDNSDEYAALIMEELDPGNVGYIELYNLETLLLQAPSHSMNLSTNSRVLSRMLSQKLKPTKERNPFKRCKRRLDYFIEDNWKRIWVMALWLSICAGLFTWKFIQYKRRAVFDVMGYCVSVAKGGAETTKFNMALVLLPVCRNTITWLRSRTKLGKIIPFDDNINFHKVIAFGIAVGVGLHAISHLTCDFPRLLHATDEEYEPMKPFFGDERPNNYWWFVKGTEGWTGVVMVVLMIIAYVLAQPWFRRNRLNLPSTIKKLTGFNAFWYSHHLFVIVYVLFIIHGYFLYLSKKWYKKTTWMYIAVPMILYACERLLRAFRSGYKAVKILKVAVYPGNVMAVHMSKPQGFKYTSGQYIFVNCSDVSSFQWHPFTISSAPGDDYLSMHIRTLGDWTSQLKTLFSKVCEPPTGDQSGLLRADVAKADYKPRLPKLLIDGPYGAPAQDYKKYDVVLLVGLGIGATPLISIVKDVLNNIKQQKNIEDGTKGSKRSPFATKRAYFYWVTREQGSFEWFKGVMDEVSENDQEGLIELHNYCTSVYEEGDARSALITMLQSIQQAKSGVDIVSGTRVKTHFARPNWRQVFKRVTINHPDQRIGVFYCGPQGLVGELRHLSQDFSHKTGTKFEFHKENF", "length": 867, "molWeight": 99051, "crc64": "F1D64A8DC6AC6E78", "md5": "80CBD059FF2B16963F8C24D5F0004D7B"}}
{"primaryAccession": "Q94981", "text": "This is E3 ubiquitin-protein ligase ariadne-1 protein, from Fruit fly, contains 503 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [133, 183], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [203, 264], "description": "IBR-type", "keyword_description": "Zinc finger", "textural_description": "IBR-type Zinc finger"}, {"location": [291, 322], "description": "RING-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "RING-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q94981", "organism_name": "Fruit fly", "protein_name": "E3 ubiquitin-protein ligase ariadne-1", "length": 503, "firstPublicDate": "2001-09-26", "FUNCTION": "Atypical E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 Ubc10 (PubMed:10880484, PubMed:21900267, PubMed:29689197), Controls the subcellular localization and morphology of muscle nuclei (myonuclei) by regulating the protein levels and distribution of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex (PubMed:29689197), Functions by mediating the monoubiquitination of the LINC complex subunit koi leading to its subsequent proteasomal degradation (PubMed:29689197), Appears to function, at least partially redundantly, with the RBR E3 ligase family member park in nuclear localization and morphology (PubMed:29689197), Likely to function in metamorphosis by regulating the proteins levels of EcR isoform A (ECR-A) and its heterodimeric partner usp, via the ubiquitination and subsequent degradation of ECR-A (PubMed:21900267)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the RBR family, Ariadne subfamily", "domain_description": {"RING-type Zinc finger": 1, "IBR-type Zinc finger": 1, "RING-type 2; atypical Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDSDNDNDFCDNVDSGNVSSGDDGDDDFGMEVDLPSSADRQMDQDDYQYKVLTTDEIVQHQREIIDEANLLLKLPTPTTRILLNHFKWDKEKLLEKYFDDNTDEFFKCAHVINPFNATEAIKQKTSRSQCEECEICFSQLPPDSMAGLECGHRFCMPCWHEYLSTKIVAEGLGQTISCAAHGCDILVDDVTVANLVTDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVKVPYAEPRRVHCKCGHVFCFACGENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKDGGCNHMVCKNQNCKNEFCWVCLGSWEPHGSSWYNCNRYDEDEAKTARDAQEKLRSSLARYLHYYNRYMNHMQSMKFENKLYASVKQKMEEMQQHNMSWIEVQFLKKAVDILCQCRQTLMYTYVFAYYLKKNNQSMIFEDNQKDLESATEMLSEYLERDITSENLADIKQKVQDKYRYCEKRCSVLLKHVHEGYDKEWWEYTE", "length": 503, "molWeight": 58932, "crc64": "0AECCE256CF5EC00", "md5": "80D72AF78F6AF31F0EECCE18649954EF"}}
{"primaryAccession": "Q949Q5", "text": "This is Photosystem I subunit O protein, from Mouse-ear cress, contains 140 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q949Q5", "organism_name": "Mouse-ear cress", "protein_name": "Photosystem I subunit O", "length": 140, "firstPublicDate": "2014-09-03", "FUNCTION": "Involved in the balancing of excitation energy between the two photosystems I (PSI) and II (PSII)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the PSAO family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAATFATPSTVIGLGGSSITTKPFSSSFLKPTLSAKNPLRLAGASGGRVTCFERNWLRRDLNVVGFGLIGWLAPSSIPAINGKSLTGLFFDSIGTELAHFPTPPALTSQFWLWLVTWHLGLFLCLTFGQIGFKGRTEDYF", "length": 140, "molWeight": 15144, "crc64": "4BBDFCB2A4D3EA90", "md5": "6F6E35129E0C2727883F8FC3FAE61286"}}
{"primaryAccession": "Q949S9", "text": "This is Pre-mRNA-splicing factor SPF27 homolog protein, from Mouse-ear cress, contains 253 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q949S9", "organism_name": "Mouse-ear cress", "protein_name": "Pre-mRNA-splicing factor SPF27 homolog", "length": 253, "firstPublicDate": "2010-02-09", "FUNCTION": "Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity, Involved in mRNA splicing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SPF27 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATNNGDVLMLEATPEAARPWASAANAEVIDALPYIDDDYGNPLIKSEVDRLVEEEMRRSSKKPADFLKDLPPLPKFDFKNCPVLGKEYERVRAGKPPVRIDFESRYKLEMPPANKRNDDAAWKQYLQKNQRSLQQKLIELENLELMSKLGPELWRQNNHRLEVFLTRMQRLAQEQNEEIEKVNRERKYHQQTTSYELNALSQEWRQLCVKNMEIQSACAMLETQIDSFKKEAAERGWNLEEKLENVEPLQMQ", "length": 253, "molWeight": 29680, "crc64": "04323FBBFD7F92FD", "md5": "6381F9DF64E1AEB6829E95A8FCACA84C"}}
{"primaryAccession": "Q94AP3", "text": "This is Protein WALLS ARE THIN 1 protein, from Mouse-ear cress, contains 389 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94AP3", "organism_name": "Mouse-ear cress", "protein_name": "Protein WALLS ARE THIN 1", "length": 389, "firstPublicDate": "2013-03-06", "FUNCTION": "Required for secondary wall formation in fibers, especially in short days conditions, Promotes indole metabolism and transport (e,g, tryptophan, neoglucobrassicin and auxin (indole-3-acetic acid)), May prevent salicylic-acid (SA) accumulation", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the drug/metabolite transporter (DMT) superfamily, Plant drug/metabolite exporter (P-DME) (TC 2,A,7,4) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MADNTDNRRSLWGVPEKLQLHIAMLTLQFGYAGFHVVSRAALNMGISKLVFPVYRNIIALLLLLPFAYFLEKKERPAITLNFLIQFFFLALIGITANQGFYLLGLDNTSPTFASSMQNSVPAITFLMAALLRIEKVRINRRDGISKILGTALCVAGASVITLYKGPTIYTPASHLHAHLLTTNSAVLAPLGNAAPKNWTLGCIYLIGHCLSWSGWLVFQAPVLKSYPARLSVTSYTCFFGIIQFLIIAAFCERDSQAWVFHSGWELFTILYAGIVASGIAFAVQIWCIDRGGPVFVAVYQPVQTLVVAIMASIALGEEFYLGGIIGAVLIIAGLYFVLYGKSEERKFAALEKAAIQSSAEHGIERAPVSRNSIKSSITTPLLHQSTDNV", "length": 389, "molWeight": 42571, "crc64": "19D964BF4198A01E", "md5": "E8AD0CB905E41DC0B1D2079FCD846197"}}
{"primaryAccession": "Q94BP7", "text": "This is AUGMIN subunit 6 protein, from Mouse-ear cress, contains 741 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94BP7", "organism_name": "Mouse-ear cress", "protein_name": "AUGMIN subunit 6", "length": 741, "firstPublicDate": "2015-10-14", "FUNCTION": "Contributes to the assembly of the acentrosomal spindle and phragmoplast microtubule arrays as part of the augmin complex", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the HAUS6 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTMDREKERELELESAMYTNCLLLGLDPNVIGLGASNGTPRVGLFRHSNPKLGEQLLYFILSSLRGPAQSSKDFDKVWPIFDSAQSRDFRKVVQAIISELESQGALPRSNSRVSSLATCCGPRFVELLWQLSLHALREVHRRTFPADVASNPLPSSLTDVSFSHAATLLPVTKARIVLERRRFLKNAETAVQRQAMWSNLAHEMTAEFRGLCAEEAYLQQELEKLNDLRNKVKQEGEVWDDLVSSSSQNSHLVSKATRLWDSIMARKGQHEVLASGPIEDLIAHREHRYRISGSALLAAMDQSSQVPRAELLSAHSDDSASLADDKELSDGSYTNMHDHSLVDSFETASSQASDETLSRVDDRGGKINQTVDVAEVIRRWTHALQRIHKQSLLLAKANDGDGPDILRTASDGGTSGHVESLAATLTEHQQHLASFQVLINQLKEVSPAIQKSISECTEMVNSLPPTLPPVTRSNGQASSLLQSQGSGRIMEGVSNDVAELTSTMSNVQLEKVSASPTLKLPQLFSSTPTSSGKGGNGQKRQTMASQVNKMESLSEKNSTDQALSNARPDNLPTDTSSSFVHNLKKSVREAALLIPSSAGSSRDSQSDEGSEHYFVPLSATGFSRFPSETKALPLRGSRALTSLSEPSFLEPNVPDSFAPSKYSDIPDTYDDLDSFKDYDNGNGFLSVAGSNSVASDAQQSFYDIDDQVFSPPLLMDSSLLSDAYEDLLAPLSETEAALMEH", "length": 741, "molWeight": 80935, "crc64": "EF2E940CA79D28F3", "md5": "75D590FACA196006C42CD276ABA86433"}}
{"primaryAccession": "Q94ID1", "text": "This is Adenylate isopentenyltransferase 7, mitochondrial protein, from Mouse-ear cress, contains 329 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94ID1", "organism_name": "Mouse-ear cress", "protein_name": "Adenylate isopentenyltransferase 7, mitochondrial", "length": 329, "firstPublicDate": "2010-02-09", "FUNCTION": "Involved in cytokinin biosynthesis, Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the IPP transferase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKFSISSLKQVQPILCFKNKLSKVNVNSFLHPKEKVIFVMGATGSGKSRLAIDLATRFQGEIINSDKIQLYKGLDVLTNKVTPKECRGVPHHLLGVFDSEAGNLTATQYSRLASQAISKLSANNKLPIVAGGSNSYIEALVNHSSGFLLNNYDCCFIWVDVSLPVLNSFVSKRVDRMMEAGLLEEVREVFNPKANYSVGIRRAIGVPELHEYLRNESLVDRATKSKMLDVAVKNIKKNTEILACRQLKKIQRLHKKWKMSMHRVDATEVFLKRNVEEQDEAWENLVARPSERIVDKFYNNNNQLKNDDVEHCLAASYGGGSGSRAHNMI", "length": 329, "molWeight": 36980, "crc64": "66AFA61D3DE49AF8", "md5": "239FC2632473370E58B8C98C41057856"}}
{"primaryAccession": "Q94ID2", "text": "This is Adenylate isopentenyltransferase 5, chloroplastic protein, from Mouse-ear cress, contains 330 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94ID2", "organism_name": "Mouse-ear cress", "protein_name": "Adenylate isopentenyltransferase 5, chloroplastic", "length": 330, "firstPublicDate": "2010-02-09", "FUNCTION": "Involved in cytokinin biosynthesis, Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the IPP transferase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKPCMTALRQVIQPLSLNFQGNMVDVPFFRRKDKVVFVMGATGTGKSRLAIDLATRFPAEIVNSDKIQVYKGLDIVTNKVTPEESLGVPHHLLGTVHDTYEDFTAEDFQREAIRAVESIVQRDRVPIIAGGSNSYIEALVNDCVDFRLRYNCCFLWVDVSRPVLHSFVSERVDKMVDMGLVDEVRRIFDPSSSDYSAGIRRAIGVPELDEFLRSEMRNYPAETTERLLETAIEKIKENTCLLACRQLQKIQRLYKQWKWNMHRVDATEVFLRRGEEADEAWDNSVAHPSALAVEKFLSYSDDHHLEGANILLPEISAVPPLPAAVAAISR", "length": 330, "molWeight": 37395, "crc64": "145E0000E226CD03", "md5": "9D86C8389B769E2412B212D3D2BF4A04"}}
{"primaryAccession": "Q94ID3", "text": "This is Adenylate isopentenyltransferase 1, chloroplastic protein, from Mouse-ear cress, contains 357 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94ID3", "organism_name": "Mouse-ear cress", "protein_name": "Adenylate isopentenyltransferase 1, chloroplastic", "length": 357, "firstPublicDate": "2010-02-09", "FUNCTION": "Involved in cytokinin biosynthesis, Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP, ADP and AMP, Adenine, adenosine, isopentenylpyrophosphate and 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBDP) are not used as substrates", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the IPP transferase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTELNFHLLPIISDRFTTTTTTSPSFSSHSSSSSSLLSFTKRRRKHQPLVSSIRMEQSRSRNRKDKVVVILGATGAGKSRLSVDLATRFPSEIINSDKIQVYEGLEITTNQITLQDRRGVPHHLLGVINPEHGELTAGEFRSAASNVVKEITSRQKVPIIAGGSNSFVHALLAQRFDPKFDPFSSGSCLISSDLRYECCFIWVDVSETVLYEYLLRRVDEMMDSGMFEELSRFYDPVKSGLETRFGIRKAIGVPEFDGYFKEYPPEKKMIKWDALRKAAYDKAVDDIKRNTWTLAKRQVKKIEMLKDAGWEIERVDATASFKAVMMKSSSEKKWRENWEEQVLEPSVKIVKRHLVQN", "length": 357, "molWeight": 40765, "crc64": "8F37C63A3BE3ED2D", "md5": "473255AED867590CF6749B08D1AF4ABC"}}
{"primaryAccession": "Q94KI8", "text": "This is Two pore calcium channel protein 1 protein, from Mouse-ear cress, contains 733 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94KI8", "organism_name": "Mouse-ear cress", "protein_name": "Two pore calcium channel protein 1", "length": 733, "firstPublicDate": "2008-07-01", "FUNCTION": "Functions as a voltage-gated inward-rectifying Ca(2+) channel (VDCC) across the vacuole membrane, Is one of the essential components of the slow vacuolar (SV) channel, Acts as the major ROS-responsive Ca(2+) channel and is the possible target of Al-dependent inhibition, Involved in the regulation of germination and stomatal movement", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the calcium channel alpha-1 subunit (TC 1,A,1,11) family, Two pore calcium channel subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEDPLIGRDSLGGGGTDRVRRSEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYLSPLAFDFLPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFEDTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPDENTFFSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAGSKSRSQRVDTLLHHMLGDELSKPECSTSDT", "length": 733, "molWeight": 84873, "crc64": "1CA978D6B8BFF445", "md5": "3D1EE60FC3E991E439BF8E912E010996"}}
{"primaryAccession": "Q95M12", "text": "This is Legumain protein, from Bovine, contains 433 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q95M12", "organism_name": "Bovine", "protein_name": "Legumain", "length": 433, "firstPublicDate": "2006-10-31", "FUNCTION": "Has a strict specificity for hydrolysis of asparaginyl bonds, Can also cleave aspartyl bonds slowly, especially under acidic conditions, Required for normal degradation of internalized EGFR, Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity), Required for normal lysosomal protein degradation in renal proximal tubules, May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the peptidase C13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIWEFTVLLSLVLGTGAVPLEDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIVHRNGIPDEQIIVMMYDDIANSEDNPTPGIVINRPNGSDVYQGVLKDYTGEDVTPKNFLAVLRGDAEAVKGVGSGKVLKSGPRDHVFVYFTDHGATGILVFPNEDLHVKDLNETIRYMYEHKMYQKMVFYIEACESGSMMNHLPPDINVYATTAANPRESSYACYYDEQRSTFLGDWYSVNWMEDSDVEDLTKETLHKQYQLVKSHTNTSHVMQYGNKSISAMKLMQFQGLKHQASSPISLPAVSRLDLTPSPEVPLSIMKRKLMSTNDLQESRRLVQKIDRHLEARNIIEKSVRKIVTLVSGSAAEVDRLLSQRAPLTEHACYQTAVSHFRSHCFNWHNPTYEYALRHLYVLVNLCENPYPIDRIKLSMNKVCHGYY", "length": 433, "molWeight": 49284, "crc64": "48B2CF9844206AB4", "md5": "6BBC864569B9CB091CA453CFECAEFF48"}}
{"primaryAccession": "Q95XZ6", "text": "This is Lysosomal amino acid transporter 1 protein, from Caenorhabditis elegans, contains 311 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q95XZ6", "organism_name": "Caenorhabditis elegans", "protein_name": "Lysosomal amino acid transporter 1", "length": 311, "firstPublicDate": "2012-10-03", "FUNCTION": "Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes (PubMed:22822152), May play a role in the degradation of autophagic substrates in autolysosomes by regulating lysosome function (PubMed:25124690)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the laat-1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKTGGLSDFADFGEEDANCTQGIQWIKDVFTDCVDTDLKLLGFIIGLISLALWLIPLFPQLWQNYKTKKCEGLSLAFLFFWLVGDTCNMLGAILTNQQPIQKIIGVYYIIQDLVLWTQYGYYLKIYNRPTTSSARSNTIVVPVLALASVGSFFVFESALPPVGDHRVKRSFLESLNHQEGLPLEGILKMWPIFTSYTDMLGYIIGSMAAVCYFGGRIPQIIKNYRHSSCEGLSLTMFYIIVAANFTYGISVLLATTSWLYLLRHLPWLAGSLGCCCFDAVIISQYYLYRPKTPLAEDTERAGLLNSQDDSD", "length": 311, "molWeight": 34960, "crc64": "6A144B5210237353", "md5": "C215393CE514F84DEC11336D15A0F53E"}}
{"primaryAccession": "Q96285", "text": "This is L-type lectin-domain containing receptor kinase V.5 protein, from Mouse-ear cress, contains 661 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96285", "organism_name": "Mouse-ear cress", "protein_name": "L-type lectin-domain containing receptor kinase V.5", "length": 661, "firstPublicDate": "2011-01-11", "FUNCTION": "Confers resistance to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici, but confers susceptibility to the pathogenic bacteria Pseudomonas syringae", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "In the N-terminal section; belongs to the leguminous lectin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSRELIILCQPILVLFLTLFYNSHGYFVSQGSVGIGFNGYFTLTNTTKHTFGQAFENEHVEIKNSSTGVISSFSVNFFFAIVPEHNQQGSHGMTFVISPTRGLPGASSDQYLGIFNKTNNGKASNNVIAIELDIHKDEEFGDIDDNHVGININGLRSVASASAGYYDDKDGSFKKLSLISREVMRLSIVYSQPDQQLNVTLFPAEIPVPPLKPLLSLNRDLSPYLLEKMYLGFTASTGSVGAIHYLMGWLVNGVIEYPRLELSIPVLPPYPKKTSNRTKTVLAVCLTVSVFAAFVASWIGFVFYLRHKKVKEVLEEWEIQYGPHRFAYKELFNATKGFKEKQLLGKGGFGQVYKGTLPGSDAEIAVKRTSHDSRQGMSEFLAEISTIGRLRHPNLVRLLGYCRHKENLYLVYDYMPNGSLDKYLNRSENQERLTWEQRFRIIKDVATALLHLHQEWVQVIIHRDIKPANVLIDNEMNARLGDFGLAKLYDQGFDPETSKVAGTFGYIAPEFLRTGRATTSTDVYAFGLVMLEVVCGRRIIERRAAENEEYLVDWILELWENGKIFDAAEESIRQEQNRGQVELVLKLGVLCSHQAASIRPAMSVVMRILNGVSQLPDNLLDVVRAEKFREWPETSMELLLLDVNTSSSLELTDSSFVSHGR", "length": 661, "molWeight": 74436, "crc64": "C4833F3001314E38", "md5": "9CF23F8699B96E0549682C47F780037E"}}
{"primaryAccession": "Q96288", "text": "This is B-box zinc finger protein 24 protein, from Mouse-ear cress, contains 248 amino acids, has 1 B box-type 1; atypical Zinc finger, has 1 B box-type 2; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [5, 47], "description": "B box-type 1; atypical", "keyword_description": "Zinc finger", "textural_description": "B box-type 1; atypical Zinc finger"}, {"location": [57, 99], "description": "B box-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "B box-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q96288", "organism_name": "Mouse-ear cress", "protein_name": "B-box zinc finger protein 24", "length": 248, "firstPublicDate": "2001-12-05", "FUNCTION": "Acts as negative regulator of seedling photomorphogenesis and light-regulated inhibition of hypocotyl elongation (PubMed:17605755, PubMed:18540109, PubMed:21685177), BBX24/STO and BBX25/STH function as transcriptional corepressors of HY5 activity, leading to the down-regulation of BBX22 expression, BBX24/STO acts additively with BBX25/STH during de-etiolation and the hypocotyl shade avoidance response (PubMed:23624715), Functions as negative regulator of photomorphogenic UV-B responses by interacting with both COP1 and HY5 (PubMed:22410790), May act as a transcription factor in the salt-stress response (PubMed:12909688)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"B box-type 1; atypical Zinc finger": 1, "B box-type 2; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKIQCDVCEKAPATVICCADEAALCPQCDIEIHAANKLASKHQRLHLNSLSTKFPRCDICQEKAAFIFCVEDRALLCRDCDESIHVANSRSANHQRFLATGIKVALTSTICSKEIEKNQPEPSNNQQKANQIPAKSTSQQQQQPSSATPLPWAVDDFFHFSDIESTDKKGQLDLGAGELDWFSDMGFFGDQINDKALPAAEVPELSVSHLGHVHSYKPMKSNVSHKKPRFETRYDDDDEEHFIVPDLG", "length": 248, "molWeight": 27641, "crc64": "4E7A960D56741B0A", "md5": "07DDBA316063A77B0ACBE4428E5CDC42"}}
{"primaryAccession": "Q969D9", "text": "This is Thymic stromal lymphopoietin protein, from Human, contains 159 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q969D9", "organism_name": "Human", "protein_name": "Thymic stromal lymphopoietin", "length": 159, "firstPublicDate": "2007-09-11", "FUNCTION": "May act as an antimicrobial peptide in the oral cavity and on the skin", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFPFALLYVLSVSFRKIFILQLVGLVLTYDFTNCDFEKIKAAYLSTISKDLITYMSGTKSTEFNNTVSCSNRPHCLTEIQSLTFNPTAGCASLAKEMFAMKTKAALAIWCPGYSETQINATQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQQ", "length": 159, "molWeight": 18141, "crc64": "FE158129406E3963", "md5": "6D56ACAA2CB039F4073868E1262FBB34"}}
{"primaryAccession": "Q969J2", "text": "This is Zinc finger protein with KRAB and SCAN domains 4 protein, from Human, contains 545 amino acids, has 7 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [320, 342], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [348, 370], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [376, 398], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [404, 426], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [432, 454], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [487, 509], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [515, 537], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q969J2", "organism_name": "Human", "protein_name": "Zinc finger protein with KRAB and SCAN domains 4", "length": 545, "firstPublicDate": "2002-09-19", "FUNCTION": "May be involved in the transcriptional activation of MDM2 and EP300 genes", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 7}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAREPRKNAALDAQSAEDQTGLLTVKVEKEEASALTAEVRAPCSPARGPERSRQRFRGFRYPEAAGPREALSRLRELCGQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHPESGEEVVVLLEYLERQLDEPAPQVPVGDQGQELLCCKMALLTQTQGSQSSQCQPMKALFKHESLGSQPLHDRVLQVPGLAQGGCCREDAMVASRLTPGSQGLLKMEDVALTLTPGWTQLDSSQVNLYRDEKQENHSSLVSLGGEIQTKSRDLPPVKKLPEKEHGKICHLREDIAQIPTHAEAGEQEGRLQRKQKNAIGSRRHYCHECGKSFAQSSGLTKHRRIHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYECDDCGKTFSQSCSLLEHHKIHTGEKPYQCNMCGKAFRRNSHLLRHQRIHGDKNVQNPEHGESWESQGRTESQWENTEAPVSYKCNECERSFTRNRSLIEHQKIHTGEKPYQCDTCGKGFTRTSYLVQHQRSHVGKKTLSQ", "length": 545, "molWeight": 61579, "crc64": "CCFB6B5D976926ED", "md5": "2CCB7D98679A8725A9C6FC9B87C7FACC"}}
{"primaryAccession": "Q969V3", "text": "This is BOS complex subunit NCLN protein, from Human, contains 563 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q969V3", "organism_name": "Human", "protein_name": "BOS complex subunit NCLN", "length": 563, "firstPublicDate": "2005-06-21", "FUNCTION": "Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:36261522, PubMed:32820719), The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (PubMed:36261522), May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NOMO (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the nicastrin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLEEAGEVLENMLKASCLPLGFIVFLPAVLLLVAPPLPAADAAHEFTVYRMQQYDLQGQPYGTRNAVLNTEARTMAAEVLSRRCVLMRLLDFSYEQYQKALRQSAGAVVIILPRAMAAVPQDVVRQFMEIEPEMLAMETAVPVYFAVEDEALLSIYKQTQAASASQGSASAAEVLLRTATANGFQMVTSGVQSKAVSDWLIASVEGRLTGLGGEDLPTIVIVAHYDAFGVAPWLSLGADSNGSGVSVLLELARLFSRLYTYKRTHAAYNLLFFASGGGKFNYQGTKRWLEDNLDHTDSSLLQDNVAFVLCLDTVGRGSSLHLHVSKPPREGTLQHAFLRELETVAAHQFPEVRFSMVHKRINLAEDVLAWEHERFAIRRLPAFTLSHLESHRDGQRSSIMDVRSRVDSKTLTRNTRIIAEALTRVIYNLTEKGTPPDMPVFTEQMQIQQEQLDSVMDWLTNQPRAAQLVDKDSTFLSTLEHHLSRYLKDVKQHHVKADKRDPEFVFYDQLKQVMNAYRVKPAVFDLLLAVGIAAYLGMAYVAVQHFSLLYKTVQRLLVKAKTQ", "length": 563, "molWeight": 62974, "crc64": "5E74EDF6ABA6F44F", "md5": "CE9020A2D31063578EC8BB817D491F1C"}}
{"primaryAccession": "Q969X6", "text": "This is U3 small nucleolar RNA-associated protein 4 homolog protein, from Human, contains 686 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q969X6", "organism_name": "Human", "protein_name": "U3 small nucleolar RNA-associated protein 4 homolog", "length": 686, "firstPublicDate": "2004-01-16", "FUNCTION": "(Microbial infection) Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5'-GGGACTTTCC-3' found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGEFKVHRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYFQEKFFPGHESRATEALCWAEGQRLFSAGLNGEIMEYDLQALNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSVKLFQITPDKIQFERNFDRQKSRILSLSWHPSGTHIAAGSIDYISVFDVKSGSAVHKMIVDRQYMGVSKRKCIVWGVAFLSDGTIISVDSAGKVQFWDSATGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVTSNSSEKQWVRTKPFQHHTHDVRTVAHSPTALISGGTDTHLVFRPLMEKVEVKNYDAALRKITFPHRCLISCSKKRQLLLFQFAHHLELWRLGSTVATGKNGDTLPLSKNADHLLHLKTKGPENIICSCISPCGSWIAYSTVSRFFLYRLNYEHDNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGALHIVQLSGGSFKHLHAFQPQSGTVEAMCLLAVSPDGNWLAASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMAIAPNTNNLVIAHSDQQVFEYSIPDKQYTDWSRTVQKQGFHHLWLQRDTPITHISFHPKRPMHILLHDAYMFCIIDKSLPLPNDKTLLYNPFPPTNESDVIRRRTAHAFKISKIYKPLLFMDLLDERTLVAVERPLDDIIAQLPPPIKKKKFGT", "length": 686, "molWeight": 76890, "crc64": "595D8B2F47C03299", "md5": "AC404F57D1981566D51AC12843A53D41"}}
{"primaryAccession": "Q96AG3", "text": "This is Mitochondrial outer membrane protein SLC25A46 protein, from Human, contains 418 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96AG3", "organism_name": "Human", "protein_name": "Mitochondrial outer membrane protein SLC25A46", "length": 418, "firstPublicDate": "2007-06-26", "FUNCTION": "Transmembrane protein of the mitochondrial outer membrane that controls mitochondrial organization (PubMed:26168012, PubMed:27543974, PubMed:27390132), May regulate the assembly of the MICOS (mitochondrial contact site and cristae organizing system) complex which is essential to the biogenesis and dynamics of mitochondrial cristae, the inwards folds of the inner mitochondrial membrane (PubMed:27390132), Through its interaction with the EMC (endoplasmic reticulum membrane protein complex), could regulate mitochondrial lipid homeostasis and thereby mitochondrial fission (PubMed:27390132)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MHPRRPDGFDGLGYRGGARDEQGFGGAFPARSFSTGSDLGHWVTTPPDIPGSRNLHWGEKSPPYGVPTTSTPYEGPTEEPFSSGGGGSVQGQSSEQLNRFAGFGIGLASLFTENVLAHPCIVLRRQCQVNYHAQHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGIISEFTPLPREVLHKWSPKQIGEHLLLKSLTYVVAMPFYSASLIETVQSEIIRDNTGILECVKEGIGRVIGMGVPHSKRLLPLLSLIFPTVLHGVLHYIISSVIQKFVLLILKRKTYNSHLAESTSPVQSMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVLPINTQYEGMRDCINTIRQEEGVFGFYKGFGAVIIQYTLHAAVLQITKIIYSTLLQNNI", "length": 418, "molWeight": 46174, "crc64": "97341574207816AB", "md5": "0E3E424CFD889D7B774ECFE2BDEF15AF"}}
{"primaryAccession": "Q96AY2", "text": "This is Crossover junction endonuclease EME1 protein, from Human, contains 570 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96AY2", "organism_name": "Human", "protein_name": "Crossover junction endonuclease EME1", "length": 570, "firstPublicDate": "2006-02-21", "FUNCTION": "Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick, Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions, May be required in mitosis for the processing of stalled or collapsed replication forks", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the EME1/MMS4 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDISDCEASCPPAPELFSPPVPEIAETVTQTQPVRLLSSESEDEEEFIPLAQRLTCKFLTHKQLSPEDSSSPVKSVLDHQNNEGASCDWKKPFPKIPEVPLHDTPERSAADNKDLILDPCCQLPAYLSTCPGQSSSLAVTKTNSDILPPQKKTKPSQKVQGRGSHGCRQQRQARQKESTLRRQERKNAALVTRMKAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIEAQAVPCSVTWRRRAGPSEDREDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTDITAKTAGKALSLVIVDQEKCFSAQNPPRRGKQGANKQTKKQQQRQPEASIGSMVSRVDAEEALVDLQLHTEAQAQIVQSWKELADFTCAFTKAVAEAPFKKLRDETTFSFCLESDWAGGVKVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYQQCFSDKERQNLLADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQPHLSLDSAD", "length": 570, "molWeight": 63252, "crc64": "BA08F5655761AF85", "md5": "7B157D24BD4D3E4935B98662E14BB647"}}
{"primaryAccession": "Q96B02", "text": "This is Ubiquitin-conjugating enzyme E2 W protein, from Human, contains 151 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96B02", "organism_name": "Human", "protein_name": "Ubiquitin-conjugating enzyme E2 W", "length": 151, "firstPublicDate": "2006-04-18", "FUNCTION": "Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:20061386, PubMed:21229326), Specifically monoubiquitinates the N-terminus of various substrates, including ATXN3, MAPT/TAU, POLR2H/RPB8 and STUB1/CHIP, by recognizing backbone atoms of disordered N-termini (PubMed:23560854, PubMed:23696636, PubMed:25436519), Involved in degradation of misfolded chaperone substrates by mediating monoubiquitination of STUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length of ubiquitin chain attached to STUB1/CHIP substrates by ATXN3, After UV irradiation, but not after mitomycin-C (MMC) treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway (PubMed:19111657, PubMed:21229326), In vitro catalyzes 'Lys-11'-linked polyubiquitination, UBE2W-catalyzed ubiquitination occurs also in the presence of inactive RING/U-box type E3s, i,e, lacking the active site cysteine residues to form thioester bonds with ubiquitin, or even in the absence of E3, albeit at a slower rate (PubMed:25436519)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ubiquitin-conjugating enzyme family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASMQKRLQKELLALQNDPPPGMTLNEKSVQNSITQWIVDMEGAPGTLYEGEKFQLLFKFSSRYPFDSPQVMFTGENIPVHPHVYSNGHICLSILTEDWSPALSVQSVCLSIISMLSSCKEKRRPPDNSFYVRTCNKNPKKTKWWYHDDTC", "length": 151, "molWeight": 17331, "crc64": "276B585BBC4CEB71", "md5": "1205359A83DF1F9FD7BD2C187E2B179F"}}
{"primaryAccession": "Q96BF6", "text": "This is Nucleus accumbens-associated protein 2 protein, from Human, contains 587 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96BF6", "organism_name": "Human", "protein_name": "Nucleus accumbens-associated protein 2", "length": 587, "firstPublicDate": "2006-12-12", "FUNCTION": "Functions as a transcriptional repressor through its association with the NuRD complex, Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAMELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRTVMGSAAASVPLDPEFPPAAAQVFEQRIYAERRGDAATIVALRTDAVNVDLSAAANPAFDAGEEVDGAGSVIQEVAAPEPLPADGQSPPQPFEQGGGGPSRPQTPAAAARRPEGTYAGTL", "length": 587, "molWeight": 62837, "crc64": "BE1EF06B210EEDBA", "md5": "4BCC9ABA32DEEF4C4241F7EB1CE00242"}}
{"primaryAccession": "Q96BN2", "text": "This is Transcriptional adapter 1 protein, from Human, contains 335 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96BN2", "organism_name": "Human", "protein_name": "Transcriptional adapter 1", "length": 335, "firstPublicDate": "2008-02-05", "FUNCTION": "Probably involved in transcriptional regulation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TADA1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPDGAGSLPWPGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIITKLWHPNHEELQQDKVHRQRLAAKEGLLLC", "length": 335, "molWeight": 37382, "crc64": "1B07D4613107A584", "md5": "FBFB07D880E5DF4541E8B46AFBA2AA13"}}
{"primaryAccession": "Q96BP3", "text": "This is Peptidylprolyl isomerase domain and WD repeat-containing protein 1 protein, from Human, contains 646 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96BP3", "organism_name": "Human", "protein_name": "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "length": 646, "firstPublicDate": "2006-06-13", "FUNCTION": "PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357), May be involved in pre-mRNA splicing (PubMed:11991638)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the cyclophilin-type PPIase family, PPIL1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAESGSDFQQRRRRRRDPEEPEKTELSERELAVAVAVSQENDEENEERWVGPLPVEATLAKKRKVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGSDRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIVCTSFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMAATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK", "length": 646, "molWeight": 73575, "crc64": "4DEFA1C78F914430", "md5": "080660001680A0F5BFFD5E80694D2069"}}
{"primaryAccession": "Q96BY9", "text": "This is Store-operated calcium entry-associated regulatory factor protein, from Human, contains 339 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96BY9", "organism_name": "Human", "protein_name": "Store-operated calcium entry-associated regulatory factor", "length": 339, "firstPublicDate": "2006-01-10", "FUNCTION": "Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling, In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the SARAF family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAACGPGAAGYCLLLGLHLFLLTAGPALGWNDPDRMLLRDVKALTLHYDRYTTSRRLDPIPQLKCVGGTAGCDSYTPKVIQCQNKGWDGYDVQWECKTDLDIAYKFGKTVVSCEGYESSEDQYVLRGSCGLEYNLDYTELGLQKLKESGKQHGFASFSDYYYKWSSADSCNMSGLITIVVLLGIAFVVYKLFLSDGQYSPPPYSEYPPFSHRYQRFTNSAGPPPPGFKSEFTGPQNTGHGATSGFGSAFTGQQGYENSGPGFWTGLGTGGILGYLFGSNRAATPFSDSWYYPSYPPSYPGTWNRAYSPLHGGSGSYSVCSNSDTKTRTASGYGGTRRR", "length": 339, "molWeight": 36975, "crc64": "83CC0517AB635FE9", "md5": "CAD052FD79C66742D1E014643C2D1169"}}
{"primaryAccession": "Q96C03", "text": "This is Mitochondrial dynamics protein MID49 protein, from Human, contains 454 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96C03", "organism_name": "Human", "protein_name": "Mitochondrial dynamics protein MID49", "length": 454, "firstPublicDate": "2007-11-13", "FUNCTION": "Mitochondrial outer membrane protein involved in the regulation of mitochondrial organization (PubMed:29361167), It is required for mitochondrial fission and promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins, Regulates DNM1L GTPase activity", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MID49/MID51 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIATLAVKRFIDRATSPRDEDDTKADSWKELSLLKATPHLQPRPPPAALSQPVLPLAPSSSAPEGPAETDPEVTPQLSSPAPLCLTLQERLLAFERDRVTIPAAQVALAKQLAGDIALELQAYFRSKFPELPFGAFVPGGPLYDGLQAGAADHVRLLVPLVLEPGLWSLVPGVDTVARDPRCWAVRRTQLEFCPRGSSPWDRFLVGGYLSSRVLLELLRKALAASVNWPAIGSLLGCLIRPSMASEELLLEVQHERLELTVAVLVAVPGVDADDRLLLAWPLEGLAGNLWLQDLYPVEAARLRALDDHDAGTRRRLLLLLCAVCRGCSALGQLGRGHLTQVVLRLGEDNVDWTEEALGERFLQALELLIGSLEQASLPCHFNPSVNLFSSLREEEIDDIGYALYSGLQEPEGLL", "length": 454, "molWeight": 49269, "crc64": "CEE9A444C0F8BC04", "md5": "80AD0C381AE4AC9F3E600D56E18318D8"}}
{"primaryAccession": "Q96C10", "text": "This is ATP-dependent RNA helicase DHX58 protein, from Human, contains 678 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96C10", "organism_name": "Human", "protein_name": "ATP-dependent RNA helicase DHX58", "length": 678, "firstPublicDate": "2004-07-19", "FUNCTION": "Acts as a regulator of RIGI and IFIH1/MDA5 mediated antiviral signaling, Cannot initiate antiviral signaling as it lacks the CARD domain required for activating MAVS/IPS1-dependent signaling events, Can have both negative and positive regulatory functions related to RIGI and IFIH1/MDA5 signaling and this role in regulating signaling may be complex and could probably depend on characteristics of the infecting virus or target cells, or both, Its inhibitory action on RIG-I signaling may involve the following mechanisms: competition with RIGI for binding to the viral RNA, binding to RIGI and inhibiting its dimerization and interaction with MAVS/IPS1, competing with IKBKE in its binding to MAVS/IPS1 thereby inhibiting activation of interferon regulatory factor 3 (IRF3), Its positive regulatory role may involve unwinding or stripping nucleoproteins of viral RNA thereby facilitating their recognition by RIGI and IFIH1/MDA5, Involved in the innate immune response to various RNA viruses and some DNA viruses such as poxviruses and coronavirus SARS-CoV-2, and also to the bacterial pathogen Listeria monocytogenes (PubMed:31256877), Can bind both ssRNA and dsRNA, with a higher affinity for dsRNA, Shows a preference to 5'-triphosphorylated RNA, although it can recognize RNA lacking a 5'-triphosphate", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the helicase family, RLR subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLVTQHGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEHVELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTASPGTGGASKLDGAINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKKLMDQIHDHLEMPELSRKFGTQMYEQQVVKLSEAAALAGLQEQRVYALHLRRYNDALLIHDTVRAVDALAALQDFYHREHVTKTQILCAERRLLALFDDRKNELAHLATHGPENPKLEMLEKILQRQFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQQEVIQKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYAFVATEGSRELKRELINEALETLMEQAVAAVQKMDQAEYQAKIRDLQQAALTKRAAQAAQRENQRQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKVFKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVPDFDFLQHCAENLSDLSLD", "length": 678, "molWeight": 76613, "crc64": "859E1749C7313D06", "md5": "69937E623769C7B8BBD033DE6D5FF8CC"}}
{"primaryAccession": "Q96CJ1", "text": "This is ELL-associated factor 2 protein, from Human, contains 260 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96CJ1", "organism_name": "Human", "protein_name": "ELL-associated factor 2", "length": 260, "firstPublicDate": "2005-08-30", "FUNCTION": "Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity), Acts as a transcriptional transactivator of ELL and ELL2 elongation activities, Potent inducer of apoptosis in prostatic and non-prostatic cell lines, Inhibits prostate tumor growth in vivo", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the EAF family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNSAAGFSHLDRRERVLKLGESFEKQPRCAFHTVRYDFKPASIDTSSEGYLEVGEGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKTRVEGSSKIQYRKEQQQQQMWNSARTPNLVKHSPSEDKMSPASPIDDIERELKAEASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEDEDCKSSTSDTGNCVSGHPTMTQYRIPDIDASHNRFRDNSGLLMNTLRNDLQLSESGSDSDD", "length": 260, "molWeight": 28792, "crc64": "2CDCE96FA387C799", "md5": "7A0419B1F2A5796E7447E2DD2F3C45E8"}}
{"primaryAccession": "Q96CN5", "text": "This is Leucine-rich repeat-containing protein 45 protein, from Human, contains 670 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96CN5", "organism_name": "Human", "protein_name": "Leucine-rich repeat-containing protein 45", "length": 670, "firstPublicDate": "2006-02-21", "FUNCTION": "Component of the proteinaceous fiber-like linker between two centrioles, required for centrosome cohesion", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEEFRRSYSRLCRESGAEPQEAVLQQLHQLPRGRLDLATQSLTVETCRALGKLLPRETLCTELVLSDCMLSEEGATLLLRGLCANTVLRFLDLKGNNLRAAGAEALGKLLQQNKSIQSLTLEWNSLGTWDDAFATFCGGLAANGALQRLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNVGLLGGRALMNCLPSNRTLWRLDLAGNNIPGDVLRAVEQAMGHSQDRLTTFQENQARTHVLSKEVQHLREEKSKQFLDLMETIDKQREEMAKSSRASAARVGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLATAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQEQLFQTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAALERQLKVMASDHREALLDRESENASLREKLRLREAEIARIRDEEAQRASFLQNAVLAYVQASPVRTLSPPK", "length": 670, "molWeight": 75951, "crc64": "27F5D210721459FB", "md5": "181F9B55E34149E4ECF77534249E0C59"}}
{"primaryAccession": "Q96DI7", "text": "This is U5 small nuclear ribonucleoprotein 40 kDa protein protein, from Human, contains 357 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96DI7", "organism_name": "Human", "protein_name": "U5 small nuclear ribonucleoprotein 40 kDa protein", "length": 357, "firstPublicDate": "2005-06-07", "FUNCTION": "Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346, PubMed:30315277, PubMed:29360106, PubMed:29301961, PubMed:30705154), Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome (PubMed:9774689, PubMed:16723661, PubMed:26912367), As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ", "length": 357, "molWeight": 39311, "crc64": "DE8CADEB098E560C", "md5": "D11C710A973118587545C72708887FE2"}}
{"primaryAccession": "Q96DZ1", "text": "This is Endoplasmic reticulum lectin 1 protein, from Human, contains 483 amino acids, is soluble, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96DZ1", "organism_name": "Human", "protein_name": "Endoplasmic reticulum lectin 1", "length": 483, "firstPublicDate": "2005-09-27", "FUNCTION": "Probable lectin that binds selectively to improperly folded lumenal proteins, May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEEGGGGVRSLVPGGPVLLVLCGLLEASGGGRALPQLSDDIPFRVNWPGTEFSLPTTGVLYKEDNYVIMTTAHKEKYKCILPLVTSGDEEEEKDYKGPNPRELLEPLFKQSSCSYRIESYWTYEVCHGKHIRQYHEEKETGQKINIHEYYLGNMLAKNLLFEKEREAEEKEKSNEIPTKNIEGQMTPYYPVGMGNGTPCSLKQNRPRSSTVMYICHPESKHEILSVAEVTTCEYEVVILTPLLCSHPKYRFRASPVNDIFCQSLPGSPFKPLTLRQLEQQEEILRVPFRRNKEEDLQSTKEERFPAIHKSIAIGSQPVLTVGTTHISKLTDDQLIKEFLSGSYCFRGGVGWWKYEFCYGKHVHQYHEDKDSGKTSVVVGTWNQEEHIEWAKKNTARAYHLQDDGTQTVRMVSHFYGNGDICDITDKPRQVTVKLKCKESDSPHAVTVYMLEPHSCQYILGVESPVICKILDTADENGLLSLPN", "length": 483, "molWeight": 54858, "crc64": "35F78A1468457468", "md5": "92384DCFD92113DAC611CB02FC35DFA7"}}
{"primaryAccession": "Q96E29", "text": "This is Transcription termination factor 3, mitochondrial protein, from Human, contains 417 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96E29", "organism_name": "Human", "protein_name": "Transcription termination factor 3, mitochondrial", "length": 417, "firstPublicDate": "2006-10-31", "FUNCTION": "Binds promoter DNA and regulates initiation of transcription (PubMed:17662942), Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes, Required for normal mitochondrial function (By similarity), Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mTERF family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALSAQQIPRWFNSVKLRSLINAAQLTKRFTRPARTLLHGFSAQPQISSDNCFLQWGFKTYRTSSLWNSSQSTSSSSQENNSAQSSLLPSMNEQSQKTQNISSFDSELFLEELDELPPLSPMQPISEEEAIQIIADPPLPPASFTLRDYVDHSETLQKLVLLGVDLSKIEKHPEAANLLLRLDFEKDIKQMLLFLKDVGIEDNQLGAFLTKNHAIFSEDLENLKTRVAYLHSKNFSKADVAQMVRKAPFLLNFSVERLDNRLGFFQKELELSVKKTRDLVVRLPRLLTGSLEPVKENMKVYRLELGFKHNEIQHMITRIPKMLTANKMKLTETFDFVHNVMSIPHHIIVKFPQVFNTRLFKVKERHLFLTYLGRAQYDPAKPNYISLDKLVSIPDEIFCEEIAKASVQDFEKFLKTL", "length": 417, "molWeight": 47971, "crc64": "2062EFE902584696", "md5": "BE1D77ADF39DD12EEFC394E7D0702CF7"}}
{"primaryAccession": "Q96EG1", "text": "This is Arylsulfatase G protein, from Human, contains 525 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96EG1", "organism_name": "Human", "protein_name": "Arylsulfatase G", "length": 525, "firstPublicDate": "2005-10-11", "FUNCTION": "Displays arylsulfatase activity at acidic pH towards artificial substrates, such as p-nitrocatechol sulfate and also, but with a lower activity towards p-nitrophenyl sulfate and 4-methylumbelliferyl sulfate (PubMed:18283100, PubMed:29300381), Catalyzes the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin (PubMed:22689975)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the sulfatase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGWLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRCQAA", "length": 525, "molWeight": 57061, "crc64": "ADAB673A02B25754", "md5": "922131D07F3B751C5F96C8ACABC301FD"}}
{"primaryAccession": "Q96EP1", "text": "This is E3 ubiquitin-protein ligase CHFR protein, from Human, contains 664 amino acids, has 1 RING-type Zinc finger, has 1 PBZ-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [304, 343], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [633, 655], "description": "PBZ-type", "keyword_description": "Zinc finger", "textural_description": "PBZ-type Zinc finger"}], "meta_data": {"primaryAccession": "Q96EP1", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase CHFR", "length": 664, "firstPublicDate": "2004-02-02", "FUNCTION": "E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons, Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus, Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome, Promotes the ubiquitination and subsequent degradation of AURKA and PLK1, Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation, May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer, Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CHFR family", "domain_description": {"RING-type Zinc finger": 1, "PBZ-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MERPEEGKQSPPPQPWGRLLRLGAEEGEPHVLLRKREWTIGRRRGCDLSFPSNKLVSGDHCRIVVDEKSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYESLSEKQGMTQESFEANKENVFHGTKDTSGAGAGRGADPRVPPSSPATQVCFEEPQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVASDEVSSFASALPDRKTASFSSLEPQDQEDLEPVKKKMRGDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYVVCRQCPEYRRQAAQPPHCPAPEGEPGAPQALGDAPSTSVSLTTAVQDYVCPLQGSHALCTCCFQPMPDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLCYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN", "length": 664, "molWeight": 73386, "crc64": "141A1E7FEFAE36A2", "md5": "14BFCC4F1EE952C4F03191834C0CE45E"}}
{"primaryAccession": "Q96EX3", "text": "This is Cytoplasmic dynein 2 intermediate chain 2 protein, from Human, contains 536 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96EX3", "organism_name": "Human", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "length": 536, "firstPublicDate": "2004-03-15", "FUNCTION": "Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways, Inhibits the MAP3K7-induced NF-kappa-B activation pathway, Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the dynein light intermediate chain family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATRAQPGPLSQAGSAGVAALATVGVASGPGPGRPGPLQDETLGVASVPSQWRAVQGIRWETKSCQTASIATASASAQARNHVDAQVQTEAPVPVSVQPPSQYDIPRLAAFLRRVEAMVIRELNKNWQSHAFDGFEVNWTEQQQMVSCLYTLGYPPAQAQGLHVTSISWNSTGSVVACAYGRLDHGDWSTLKSFVCAWNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWRTGLTDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPSSVPLRAPAQFTFSPHGGPIYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLTSLQLSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESPVYCLEFNSQQTQLLAAGDAQGTVKVWQLSTEFTEQGPREAEDLDCLAAEVAA", "length": 536, "molWeight": 57801, "crc64": "D23C2E0055120A4C", "md5": "107CA2685769882B3C12296ED7D1A9CD"}}
{"primaryAccession": "Q96G97", "text": "This is Seipin protein, from Human, contains 398 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96G97", "organism_name": "Human", "protein_name": "Seipin", "length": 398, "firstPublicDate": "2005-04-26", "FUNCTION": "Plays a crucial role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (PubMed:19278620, PubMed:21533227, PubMed:31708432, PubMed:30293840), In association with LDAF1, defines the sites of LD formation in the ER (PubMed:31708432), Also required for growth and maturation of small nascent LDs into larger mature LDs (PubMed:27564575), Mediates the formation and/or stabilization of endoplasmic reticulum-lipid droplets (ER-LD) contacts, facilitating protein and lipid delivery from the ER into growing LDs (PubMed:31178403, PubMed:27879284), Regulates the maturation of ZFYVE1-positive nascent LDs and the function of the RAB18-ZFYVE1 complex in mediating the formation of ER-LD contacts (PubMed:30970241), Binds anionic phospholipids including phosphatidic acid (PubMed:30293840), Plays an important role in the differentiation and development of adipocytes (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the seipin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLEVELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVASNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS", "length": 398, "molWeight": 44392, "crc64": "9FB1B37E72493DB9", "md5": "6E5B629C3034F8EE9264E2F932A4ECF9"}}
{"primaryAccession": "Q96GG9", "text": "This is DCN1-like protein 1 protein, from Human, contains 259 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96GG9", "organism_name": "Human", "protein_name": "DCN1-like protein 1", "length": 259, "firstPublicDate": "2005-08-30", "FUNCTION": "Part of an E3 ubiquitin ligase complex for neddylation (PubMed:18826954), Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes (PubMed:26906416, PubMed:23201271, PubMed:19617556, PubMed:23401859), Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates, Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity (PubMed:25349211, PubMed:28581483), Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV", "length": 259, "molWeight": 30124, "crc64": "F3709235E0610C54", "md5": "B78DB427A9E754BE5DA5AD0EA24FEB68"}}
{"primaryAccession": "Q96GM5", "text": "This is SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 protein, from Human, contains 515 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96GM5", "organism_name": "Human", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "length": 515, "firstPublicDate": "2003-01-17", "FUNCTION": "Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology), Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:8804307, PubMed:29374058), Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex), During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state, The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes, As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF), The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells, The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity), Has a strong influence on vitamin D-mediated transcriptional activity from an enhancer vitamin D receptor element (VDRE), May be a link between mammalian SWI-SNF-like chromatin remodeling complexes and the vitamin D receptor (VDR) heterodimer (PubMed:14698202), Mediates critical interactions between nuclear receptors and the BRG1/SMARCA4 chromatin-remodeling complex for transactivation (PubMed:12917342), Interacts with AKIRIN2 (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SMARCD family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPRPGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRNHNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT", "length": 515, "molWeight": 58233, "crc64": "E683AA1E345DA400", "md5": "CA6A397F043B1CCBBAB7B313E45C9F3F"}}
{"primaryAccession": "Q96GX9", "text": "This is Methylthioribulose-1-phosphate dehydratase protein, from Human, contains 242 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96GX9", "organism_name": "Human", "protein_name": "Methylthioribulose-1-phosphate dehydratase", "length": 242, "firstPublicDate": "2006-05-30", "FUNCTION": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P), Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation, May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the aldolase class II family, MtnB subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSGCDAREGDCCSRRCGAQDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATLLFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV", "length": 242, "molWeight": 27125, "crc64": "9B8D5D1435D6775A", "md5": "2A87A71E9F52C2A60EA24B124FAF6334"}}
{"primaryAccession": "Q96HY6", "text": "This is DDRGK domain-containing protein 1 protein, from Human, contains 314 amino acids, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96HY6", "organism_name": "Human", "protein_name": "DDRGK domain-containing protein 1", "length": 314, "firstPublicDate": "2003-09-26", "FUNCTION": "Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, which plays a key role in reticulophagy (also called ER-phagy) (PubMed:32160526), In response to endoplasmic reticulum stress, promotes recruitment of the E3 UFM1-protein ligase UFL1 to the endoplasmic reticulum membrane: in turn, UFL1 mediates ufmylation of proteins such as RPN1 and RPL26/uL24, promoting reticulophagy of endoplasmic reticulum sheets (PubMed:32160526), Ufmylation-dependent reticulophagy inhibits the unfolded protein response (UPR) by regulating ERN1/IRE1-alpha stability (PubMed:28128204, PubMed:32160526), Ufmylation in response to endoplasmic reticulum stress is essential for processes such as hematopoiesis or inflammatory response (By similarity), Required for TRIP4 ufmylation, thereby regulating nuclear receptors-mediated, transcription (PubMed:25219498), May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B (PubMed:23675531), Plays a role in cartilage development through SOX9, inhibiting the ubiquitin-mediated proteasomal degradation of this transcriptional regulator (PubMed:28263186)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DDRGK1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVAPVWYLVAAALLVGFILFLTRSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNSLIAWGRESPAQAPA", "length": 314, "molWeight": 35611, "crc64": "2190D30B0D6D674A", "md5": "F4292AF4D6571B315CEEE37E72EC3621"}}
{"primaryAccession": "Q96HY7", "text": "This is 2-oxoadipate dehydrogenase complex component E1 protein, from Human, contains 919 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96HY7", "organism_name": "Human", "protein_name": "2-oxoadipate dehydrogenase complex component E1", "length": 919, "firstPublicDate": "2007-10-23", "FUNCTION": "2-oxoadipate dehydrogenase (E1a) component of the 2-oxoadipate dehydrogenase complex (OADHC) (PubMed:29191460, PubMed:29752936, PubMed:32303640, PubMed:32633484, PubMed:32695416), Participates in the first step, rate limiting for the overall conversion of 2-oxoadipate (alpha-ketoadipate) to glutaryl-CoA and CO(2) catalyzed by the whole OADHC (PubMed:29191460, PubMed:32695416), Catalyzes the irreversible decarboxylation of 2-oxoadipate via the thiamine diphosphate (ThDP) cofactor and subsequent transfer of the decarboxylated acyl intermediate on an oxidized dihydrolipoyl group that is covalently amidated to the E2 enzyme (dihydrolipoyllysine-residue succinyltransferase or DLST) (Probable) (PubMed:29752936, PubMed:32303640, PubMed:32633484), Can catalyze the decarboxylation of 2-oxoglutarate in vitro, but at a much lower rate than 2-oxoadipate (PubMed:29191460, PubMed:29752936, PubMed:32633484, PubMed:32695416), Responsible for the last step of L-lysine, L-hydroxylysine and L-tryptophan catabolism with the common product being 2-oxoadipate (Probable)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the alpha-ketoglutarate dehydrogenase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASATAAAARRGLGRALPLFWRGYQTERGVYGYRPRKPESREPQGALERPPVDHGLARLVTVYCEHGHKAAKINPLFTGQALLENVPEIQALVQTLQGPFHTAGLLNMGKEEASLEEVLVYLNQIYCGQISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVDLYFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDNSAQPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALNLQAHWQGLAQPEAQITTWSTGVPLDLLRFVGMKSVEVPRELQMHSHLLKTHVQSRMEKMMDGIKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAIVVCQETDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNMFVVHPTTPAQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVDPKKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDHIWSQEEPQNMGPWSFVSPRFEKQLACKLRLVGRPPLPVPAVGIGTVHLHQHEDILAKTFA", "length": 919, "molWeight": 103077, "crc64": "CD1E437F919324B6", "md5": "BFFD386012F38304089EB777F44AC022"}}
{"primaryAccession": "Q96I25", "text": "This is Splicing factor 45 protein, from Human, contains 401 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96I25", "organism_name": "Human", "protein_name": "Splicing factor 45", "length": 401, "firstPublicDate": "2003-09-19", "FUNCTION": "Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step, Involved in the regulation of alternative splicing and the utilization of cryptic splice sites, Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene, The resulting frameshift leads to sickle cell anemia", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRGGSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKIIVGDATEKDASKKSDSNPLTEILKCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAEQV", "length": 401, "molWeight": 44962, "crc64": "99FA8C5E5E998554", "md5": "97B654171F43A84F1E22B114A3DF601D"}}
{"primaryAccession": "Q96JC9", "text": "This is ELL-associated factor 1 protein, from Human, contains 268 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96JC9", "organism_name": "Human", "protein_name": "ELL-associated factor 1", "length": 268, "firstPublicDate": "2005-08-30", "FUNCTION": "Acts as a transcriptional transactivator of ELL and ELL2 elongation activities", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the EAF family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNGTANPLLDREEHCLRLGESFEKRPRASFHTIRYDFKPASIDTSCEGELQVGKGDEVTITLPHIPGSTPPMTVFKGNKRPYQKDCVLIINHDTGEYVLEKLSSSIQVKKTRAEGSSKIQARMEQQPTRPPQTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRAEVDIIEQMSSSSGSSSSDSESSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNSRPAVANGTSRPQGSNQLMNTLRNDLQLSESGSDSDD", "length": 268, "molWeight": 29042, "crc64": "0D78B586AABB0FA4", "md5": "7A72DF74A7E03DADBEDE2024D173F1F8"}}
{"primaryAccession": "Q96JW4", "text": "This is Solute carrier family 41 member 2 protein, from Human, contains 573 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96JW4", "organism_name": "Human", "protein_name": "Solute carrier family 41 member 2", "length": 573, "firstPublicDate": "2007-07-10", "FUNCTION": "Acts as a plasma-membrane magnesium transporter (PubMed:16984228), Can also mediate the transport of other divalent metal cations in an order of Ba(2+) > Ni(2+) > Co(2+) > Fe(2+) > Mn(2+) (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the SLC41A transporter family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTNSKGRSITDKTSGGPSSGGGFVDWTLRLNTIQSDKFLNLLLSMVPVIYQKNQEDRHKKANGIWQDGLSTAVQTFSNRSEQHMEYHSFSEQSFHANNGHASSSCSQKYDDYANYNYCDGRETSETTAMLQDEDISSDGDEDAIVEVTPKLPKESSGIMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFRKVTEVFILVPALLGLKGNLEMTLASRLSTAVNIGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLDHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVGVFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPDEPKGCYYPFRTFFGPGVNNKSAQVLLLLVIPGHLIFLYTIHLMKSGHTSLTIIFIVVYLFGAVLQVFTLLWIADWMVHHFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGDRDGDVGD", "length": 573, "molWeight": 62473, "crc64": "1BD0FF32AF91DA02", "md5": "51D5C691F559B10EC2E5CB59932B16B5"}}
{"primaryAccession": "Q96M02", "text": "This is (E2-independent) E3 ubiquitin-conjugating enzyme FATS protein, from Human, contains 699 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96M02", "organism_name": "Human", "protein_name": "(E2-independent) E3 ubiquitin-conjugating enzyme FATS", "length": 699, "firstPublicDate": "2007-03-06", "FUNCTION": "Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage, Acts as a p53/TP53 activator by inhibiting MDM2 binding to p53/TP53 and stimulating non-proteolytic polyubiquitination of p53/TP53, Exhibits ubiquitin ligase (E3) activity and assemble ubiquitin polymers through 'Lys-11'- (K11-), 'Lys-29'- (K29-) and 'Lys-63'- (K63)-linkages, independently of the ubiquitin-conjugating enzyme (E2), Promotes p53/TP53-dependent transcription of CDKN1A/p21, leading to robust checkpoint response, Mediates CDKN1A/p21 protein stability in a ubiquitin-independent manner, Interacts with HDAC1 and prevents binding of HDAC1 to CDKN1A/p21 and facilitates the acetylation and stabilization of CDKN1A/p21 (By similarity), May have a role in the assembly of primary cilia (Probable)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLKLSGEGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLANRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPALANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDKSLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGACPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFLPIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDPTTPEPSPAAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYDNLPEVKKKKEEQRKRVILQSNRLRAEVFKKQLLDQLLQRNAV", "length": 699, "molWeight": 77910, "crc64": "099E8CEF3C910F1E", "md5": "7AF20AFAB17A9BC6954CBBB2E5E937CE"}}
{"primaryAccession": "Q96M11", "text": "This is Centriolar and ciliogenesis-associated protein HYLS1 protein, from Human, contains 299 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96M11", "organism_name": "Human", "protein_name": "Centriolar and ciliogenesis-associated protein HYLS1", "length": 299, "firstPublicDate": "2007-05-01", "FUNCTION": "Plays a role in ciliogenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the HYLS1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEELLPDGQIWANMDPEERMLAAATAFTHICAGQGEGDVRREAQSIQYDPYSKASVAPGKRPALPVQLQYPHVESNVPSETVSEASQRLRKPVMKRKVLRRKPDGEVLVTDESIISESESGTENDQDLWDLRQRLMNVQFQEDKESSFDVSQKFNLPHEYQGISQDQLICSLQREGMGSPAYEQDLIVASRPKSFILPKLDQLSRNRGKTDRVARYFEYKRDWDSIRLPGEDHRKELRWGVREQMLCRAEPQSKPQHIYVPNNYLVPTEKKRSALRWGVRCDLANGVIPRKLPFPLSPS", "length": 299, "molWeight": 34359, "crc64": "D1EAF5F7D638802D", "md5": "56500FB13E058BEECAC85B9EFAA2D184"}}
{"primaryAccession": "Q96M32", "text": "This is Adenylate kinase 7 protein, from Human, contains 723 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96M32", "organism_name": "Human", "protein_name": "Adenylate kinase 7", "length": 723, "firstPublicDate": "2003-10-03", "FUNCTION": "Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates, Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP, Also displays broad nucleoside diphosphate kinase activity, Involved in maintaining ciliary structure and function", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "In the C-terminal section; belongs to the dpy-30 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAEEEETAALTEKVIRTQRVFINLLDSYSSGNIGKFLSNCVVGASLEEITEEEEEEDENKSAMLEASSTKVKEGTFQIVGTLSKPDSPRPDFAVETYSAISREDLLMRLLECDVIIYNITESSQQMEEAIWAVSALSEEVSHFEKRKLFILLSTVMTWARSKALDPEDSEVPFTEEDYRRRKSHPNFLDHINAEKMVLKFGKKARKFAAYVVAAGLQYGAEGGMLHTFFKMAWLGEIPALPVFGDGTNVIPTIHVLDLAGVIQNVIDHVPKPHYLVAVDESVHTLEDIVKCISKNTGPGKIQKIPRENAYLTKDLTQDCLDHLLVNLRMEALFVKENFNIRWAAQTGFVENINTILKEYKQSRGLMPIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVEEEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKTYDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVINLPESIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERELLEAQSIPLRNYLMTYVMPTLIQGLNECCNVRPEDPVDFLAEYLFKNNPEAQ", "length": 723, "molWeight": 82658, "crc64": "7A9E2BF11A4CEEF8", "md5": "D9A242FA932231860230416C6725116B"}}
{"primaryAccession": "Q96MT8", "text": "This is Centrosomal protein of 63 kDa protein, from Human, contains 703 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96MT8", "organism_name": "Human", "protein_name": "Centrosomal protein of 63 kDa", "length": 703, "firstPublicDate": "2004-12-21", "FUNCTION": "Required for normal spindle assembly (PubMed:21406398, PubMed:21983783, PubMed:26297806, PubMed:35793002), Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:21983783, PubMed:26297806), Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned (PubMed:21983783, PubMed:26297806), Also recruits CDK1 to centrosomes (PubMed:21406398), Plays a role in DNA damage response (PubMed:21406398), Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (PubMed:21406398), Promotes stabilization of FXR1 protein by inhibiting FXR1 ubiquitination (PubMed:35989368)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CEP63 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEALLEGIQNRGHGGGFLTSCEAELQELMKQIDIMVAHKKSEWEGRTHALETCLKIREQELKSLRSQLDVTHKEVGMLHQQVEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAVEAIRPREESLAEKKYTSQGQGDLDSVLSQLNFTHTSEDLLQAEVTCLEGSLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQSYSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRLRAEMQKAEDKAVEHKEILDQLESLKLENRHLSEMVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMNTKSQLEISTQMCKKQNDRIFKPTHSRTTEFKNTEFKPTHGQHRHDGIKTEHYKTDLHSPRGQASDSINPMSRVLSPLSPQISPCSSTRSLTSYSLCKTHSLPSALDTNEANFSDTMSESMNDQEEFISSCSLPVSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVRQFTALK", "length": 703, "molWeight": 81344, "crc64": "D5406B75BB19B5D0", "md5": "9763FF5A7845F7DDF34D50FC3C44D593"}}
{"primaryAccession": "Q96MU7", "text": "This is YTH domain-containing protein 1 protein, from Human, contains 727 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96MU7", "organism_name": "Human", "protein_name": "YTH domain-containing protein 1", "length": 727, "firstPublicDate": "2003-02-12", "FUNCTION": "Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs (PubMed:25242552, PubMed:26318451, PubMed:26876937, PubMed:28984244), M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:25242552, PubMed:26318451), Acts as a key regulator of exon-inclusion or exon-skipping during alternative splicing via interaction with mRNA splicing factors SRSF3 and SRSF10 (PubMed:26876937), Specifically binds m6A-containing mRNAs and promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing (PubMed:26876937), In contrast, interaction with SRSF3 prevents interaction with SRSF10, a splicing factor that promotes exon skipping: this prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing (PubMed:26876937), May also regulate alternative splice site selection (PubMed:20167602), Also involved in nuclear export of m6A-containing mRNAs via interaction with SRSF3: interaction with SRSF3 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export (PubMed:28984244), Involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts, probably by binding m6A-containing MAT2A mRNAs (By similarity), Also recognizes and binds m6A on other RNA molecules (PubMed:27602518), Involved in random X inactivation mediated by Xist RNA: recognizes and binds m6A-containing Xist and promotes transcription repression activity of Xist (PubMed:27602518), Also recognizes and binds m6A-containing single-stranded DNA (PubMed:32663306), Involved in germline development: required for spermatogonial development in males and oocyte growth and maturation in females, probably via its role in alternative splicing (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDYDIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDRRFSGVRRDVFLNGSYNDYVREFHNMGPPPPWQGMPPYPGMEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR", "length": 727, "molWeight": 84700, "crc64": "536032FD44582EAF", "md5": "CA36A0A4506361FCE7FE347D39188A9D"}}
{"primaryAccession": "Q96MW5", "text": "This is Conserved oligomeric Golgi complex subunit 8 protein, from Human, contains 612 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96MW5", "organism_name": "Human", "protein_name": "Conserved oligomeric Golgi complex subunit 8", "length": 612, "firstPublicDate": "2002-08-30", "FUNCTION": "Required for normal Golgi function", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the COG8 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATAATIPSVATATAAALGEVEDEGLLASLFRDRFPEAQWRERPDVGRYLRELSGSGLERLRREPERLAEERAQLLQQTRDLAFANYKTFIRGAECTERIHRLFGDVEASLGRLLDRLPSFQQSCRNFVKEAEEISSNRRMNSLTLNRHTEILEILEIPQLMDTCVRNSYYEEALELAAYVRRLERKYSSIPVIQGIVNEVRQSMQLMLSQLIQQLRTNIQLPACLRVIGYLRRMDVFTEAELRVKFLQARDAWLRSILTAIPNDDPYFHITKTIEASRVHLFDIITQYRAIFSDEDPLLPPAMGEHTVNESAIFHGWVLQKVSQFLQVLETDLYRGIGGHLDSLLGQCMYFGLSFSRVGADFRGQLAPVFQRVAISTFQKAIQETVEKFQEEMNSYMLISAPAILGTSNMPAAVPATQPGTLQPPMVLLDFPPLACFLNNILVAFNDLRLCCPVALAQDVTGALEDALAKVTKIILAFHRAEEAAFSSGEQELFVQFCTVFLEDLVPYLNRCLQVLFPPAQIAQTLGIPPTQLSKYGNLGHVNIGAIQEPLAFILPKRETLFTLDDQALGPELTAPAPEPPAEEPRLEPAGPACPEGGRAETQAEPPSVGP", "length": 612, "molWeight": 68424, "crc64": "2780349A5B037E55", "md5": "24D6FF752682FB55A3CC36097D7FF36A"}}
{"primaryAccession": "Q96N77", "text": "This is Zinc finger protein 641 protein, from Human, contains 438 amino acids, has 5 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [264, 286], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [292, 314], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [320, 342], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [372, 394], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [400, 422], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q96N77", "organism_name": "Human", "protein_name": "Zinc finger protein 641", "length": 438, "firstPublicDate": "2007-05-01", "FUNCTION": "Transcriptional activator, Activates transcriptional activities of SRE and AP-1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 5}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQAEDRSQFGSAAEMLSEQTAALGTGWESMNVQLDGAEPQVERGSQEERPWRTVPGPLEHLCCDLEEEPQSLQEKAQSAPWVPAIPQEGNTGDWEMAAALLAAGSQGLVTIKDVSLCFSQEEWRSLDPSQTDFYGEYVMQENCGIVVSLRFPIPKLDMLSQLEGGEEQWVPDPQDLEERDILRVTYTGDGSEHEGDTPELEAEPPRMLSSVSEDTVLWNPEHDESWDSMPSSSRGMLLGPPFLQEDSFSNLLCSTEMDSLLRPHTCPQCGKQFVWGSHLARHQQTHTGERPYSCLKCEKTFGRRHHLIRHQKTHLHDKTSRCSECGKNFRCNSHLASHQRVHAEGKSCKGQEVGESPGTRKRQRAPPVPKCHVCTECGKSFGRRHHLVRHWLTHTGEKPFQCPRCEKSFGRKHHLDRHLLTHQGQSPRNSWDRGTSVF", "length": 438, "molWeight": 49528, "crc64": "E3873D1A84CF395D", "md5": "5116E7F2DB3610E35EBB385CE5F7379E"}}
{"primaryAccession": "Q96NL6", "text": "This is Sodium channel and clathrin linker 1 protein, from Human, contains 688 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96NL6", "organism_name": "Human", "protein_name": "Sodium channel and clathrin linker 1", "length": 688, "firstPublicDate": "2008-02-05", "FUNCTION": "Adapter protein that links SCN10A to clathrin, Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAEIDFLREQNRRLNEDFRRYQMESFSKYSSVQKAVCQGEGDDTFENLVFDQSFLAPLVTEYDKHLGELNGQLKYYQKQVGEMKLQLENVIKENERLHSELKDAVEKKLEAFPLGTEVGTDIYADDETVRNLQEQLQLANQEKTQAVELWQTVSQELDRLHKLYQEHMTEAQIHVFESQKQKDQLFDFQQLTKQLHVTNENMEVTNQQFLKTVTEQSVIIEQLRKKLRQAKLELRVAVAKVEELTNVTEDLQGQMKKKEKDVVSAHGREEASDRRLQQLQSSIKQLEIRLCVTIQEANQLRTENTHLEKQTRELQAKCNELENERYEAIVRARNSMQLLEEANLQKSQALLEEKQKEEDIEKMKETVSRFVQDATIRTKKEVANTKKQCNIQISRLTEELSALQMECAEKQGQIERVIKEKKAVEEELEKIYREGRGNESDYRKLEEMHQRFLVSERSKDDLQLRLTRAENRIKQLETDSSEEISRYQEMIQKLQNVLESERENCGLVSEQRLKLQQENKQLRKETESLRKIALEAQKKAKVKISTMEHEFSIKERGFEVQLREMEDSNRNSIVELRHLLATQQKAANRWKEETKKLTESAEIRINNLKSELSRQKLHTQELLSQLEMANEKVAENEKLILEHQEKANRLQRRLSQAEERAASASQQLSVITVQRRKAASLMNLENI", "length": 688, "molWeight": 80910, "crc64": "9432F258529C47D3", "md5": "0876CDE9CCCE6B06E08F561F8559653B"}}
{"primaryAccession": "Q96NY9", "text": "This is Crossover junction endonuclease MUS81 protein, from Human, contains 551 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96NY9", "organism_name": "Human", "protein_name": "Crossover junction endonuclease MUS81", "length": 551, "firstPublicDate": "2004-04-13", "FUNCTION": "Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick, Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions, Plays an essential role in mitosis for the processing of stalled or collapsed replication forks (PubMed:28575661)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the XPF family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAPVRLGRKRPLPACPNPLFVRWLTEWRDEATRSRRRTRFVFQKALRSLRRYPLPLRSGKEAKILQHFGDGLCRMLDERLQRHRTSGGDHAPDSPSGENSPAPQGRLAEVQDSSMPVPAQPKAGGSGSYWPARHSGARVILLVLYREHLNPNGHHFLTKEELLQRCAQKSPRVAPGSARPWPALRSLLHRNLVLRTHQPARYSLTPEGLELAQKLAESEGLSLLNVGIGPKEPPGEETAVPGAASAELASEAGVQQQPLELRPGEYRVLLCVDIGETRGGGHRPELLRELQRLHVTHTVRKLHVGDFVWVAQETNPRDPANPGELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKRCGLERRVYLVEEHGSVHNLSLPESTLLQAVTNTQVIDGFFVKRTADIKESAAYLALLTRGLQRLYQGHTLRSRPWGTPGNPESGAMTSPNPLCSLLTFSDFNAGAIKNKAQSVREVFARQLMQVRGVSGEKAAALVDRYSTPASLLAAYDACATPKEQETLLSTIKCGRLQRNLGPALSRTLSQLYCSYGPLT", "length": 551, "molWeight": 61173, "crc64": "D0F331CC2269D847", "md5": "3FE709D5426F70B6C62C80C36E6CAE1A"}}
{"primaryAccession": "Q96PU5", "text": "This is E3 ubiquitin-protein ligase NEDD4-like protein, from Human, contains 975 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96PU5", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase NEDD4-like", "length": 975, "firstPublicDate": "2005-08-30", "FUNCTION": "E3 ubiquitin-protein ligase that mediates the polyubiquitination of lysine and cysteine residues on target proteins and is thereby implicated in the regulation of various signaling pathways including autophagy, innate immunity or DNA repair (PubMed:31959741, PubMed:33608556, PubMed:20064473), Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation (PubMed:15496141), Downregulates autophagy and cell growth by ubiquitinating and reducing cellular ULK1 or ASCT2 levels (PubMed:28820317, PubMed:31959741), Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, SCN2A/Nav1,2, SCN3A/Nav1,3, SCN5A/Nav1,5, SCN9A/Nav1,7, SCN10A/Nav1,8, KCNA3/Kv1,3, KCNH2, EAAT1, KCNQ2/Kv7,2, KCNQ3/Kv7,3 or CLC5 (PubMed:26363003, PubMed:27445338), Promotes ubiquitination and degradation of SGK1 and TNK2, Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (PubMed:25631046), Plays a role in dendrite formation by melanocytes (PubMed:23999003), Involved in the regulation of TOR signaling (PubMed:27694961), Ubiquitinates and regulates protein levels of NTRK1 once this one is activated by NGF (PubMed:27445338), Plays a role in antiviral innate immunity by catalyzing 'Lys-29'-linked cysteine ubiquitination of TRAF3, resulting in enhanced 'Lys-48' and 'Lys-63'-linked ubiquitination of TRAF3 (PubMed:33608556)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATGLGEPVYGLSEDEGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQFSSLIQREPSSRLRSCSVTDAVAEQGHLPPPSAPAGRARSSTVTGGEEPTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILENDPTELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD", "length": 975, "molWeight": 111932, "crc64": "2C958625B4A1AB3F", "md5": "253D984E62B5B95EDB213B357B63206D"}}
{"primaryAccession": "Q96Q11", "text": "This is CCA tRNA nucleotidyltransferase 1, mitochondrial protein, from Human, contains 434 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96Q11", "organism_name": "Human", "protein_name": "CCA tRNA nucleotidyltransferase 1, mitochondrial", "length": 434, "firstPublicDate": "2003-10-03", "FUNCTION": "Adds 2 C residues (CC-) to the 3' terminus of tRNA molecules instead of a complete CCA end as isoform 1 does (in vitro)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRCLYHWHRPVLNRRWSRLCLPKQYLFTMKLQSPEFQSLFTEGLKSLTELFVKENHELRIAGGAVRDLLNGVKPQDIDFATTATPTQMKEMFQSAGIRMINNRGEKHGTITARLHEENFEITTLRIDVTTDGRHAEVEFTTDWQKDAERRDLTINSMFLGFDGTLFDYFNGYEDLKNKKVRFVGHAKQRIQEDYLRILRYFRFYGRIVDKPGDHDPETLEAIAENAKGLAGISGERIWVELKKILVGNHVNHLIHLIYDLDVAPYIGLPANASLEEFDKVSKNVDGFSPKPVTLLASLFKVQDDVTKLDLRLKIAKEEKNLGLFIVKNRKDLIKATDSSDPLKPYQDFIIDSREPDATTRVCELLKYQGEHCLLKEMQQWSIPPFPVSGHDIRKVGISSGKEIGALLQQLREQWKKSGYQMEKDELLSYIKKT", "length": 434, "molWeight": 50128, "crc64": "60B7387E203A53D0", "md5": "A8244162E23C66D5FA32E036CCDE6115"}}
{"primaryAccession": "Q96QG7", "text": "This is Myotubularin-related protein 9 protein, from Human, contains 549 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96QG7", "organism_name": "Human", "protein_name": "Myotubularin-related protein 9", "length": 549, "firstPublicDate": "2003-07-19", "FUNCTION": "Acts as an adapter for myotubularin-related phosphatases (PubMed:19038970, PubMed:22647598), Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5-bisphosphate and MTMR6 binding affinity for phosphorylated phosphatidylinositols (PubMed:19038970, PubMed:22647598), Positively regulates lipid phosphatase MTMR7 catalytic activity (By similarity), Increases MTMR8 catalytic activity towards phosphatidylinositol 3-phosphate (PubMed:22647598), The formation of the MTMR6-MTMR9 complex, stabilizes both MTMR6 and MTMR9 protein levels (PubMed:19038970), Stabilizes MTMR8 protein levels (PubMed:22647598), Plays a role in the late stages of macropinocytosis possibly by regulating MTMR6-mediated dephosphorylation of phosphatidylinositol 3-phosphate in membrane ruffles (PubMed:24591580), Negatively regulates autophagy, in part via its association with MTMR8 (PubMed:22647598), Negatively regulates DNA damage-induced apoptosis, in part via its association with MTMR6 (PubMed:19038970, PubMed:22647598), Does not bind mono-, di- and tri-phosphorylated phosphatidylinositols, phosphatidic acid and phosphatidylserine (PubMed:19038970)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRSLNVAQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACNDQTHNMDRWLSKLEASNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLFEANNLVIWPSVAPQSLPLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETEDGMQESP", "length": 549, "molWeight": 63462, "crc64": "910F7D2907F9707E", "md5": "68B7852560CC118F7DEE25546323A2BD"}}
{"primaryAccession": "Q96S37", "text": "This is Solute carrier family 22 member 12 protein, from Human, contains 553 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96S37", "organism_name": "Human", "protein_name": "Solute carrier family 22 member 12", "length": 553, "firstPublicDate": "2007-10-23", "FUNCTION": "Electroneutral antiporter that translocates urate across the apical membrane of proximal tubular cells in exchange for monovalent organic or inorganic anions (PubMed:12024214, PubMed:22194875, PubMed:35144162, PubMed:35462902), Involved in renal reabsorption of urate and helps maintaining blood levels of uric acid (PubMed:12024214, PubMed:22194875), Mediates urate uptake by an exchange with organic anions such as (S)-lactate and nicotinate, and inorganic anion Cl(-) (PubMed:12024214), Other inorganic anions such as Br(-), I(-) and NO3(-) may also act as counteranions that exchange for urate (PubMed:12024214), Also mediates orotate tubular uptake coupled with nicotinate efflux and to a lesser extent with lactate efflux, therefore displaying a potential role in orotate renal reabsorption (PubMed:21350910), Orotate transport is Cl(-)-dependent (PubMed:21350910)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAPLLDNSTAQASILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF", "length": 553, "molWeight": 59630, "crc64": "E3F29F38129BAD61", "md5": "1FCF70A3F561CE8B7F99B6DF313B81A9"}}
{"primaryAccession": "Q96S94", "text": "This is Cyclin-L2 protein, from Human, contains 520 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96S94", "organism_name": "Human", "protein_name": "Cyclin-L2", "length": 520, "firstPublicDate": "2005-11-08", "FUNCTION": "Involved in pre-mRNA splicing, May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the cyclin family, Cyclin L subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYARKKVDLTHLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHRR", "length": 520, "molWeight": 58147, "crc64": "4341E55D03D7B0E0", "md5": "8AE857B7641A9DC785B2732BB6127BF4"}}
{"primaryAccession": "Q96T37", "text": "This is RNA-binding protein 15 protein, from Human, contains 977 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96T37", "organism_name": "Human", "protein_name": "RNA-binding protein 15", "length": 977, "firstPublicDate": "2002-03-27", "FUNCTION": "RNA-binding protein that acts as a key regulator of N6-methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as hematopoietic cell homeostasis, alternative splicing of mRNAs and X chromosome inactivation mediated by Xist RNA (PubMed:27602518), Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (By similarity), Plays a key role in m6A methylation, possibly by binding target RNAs and recruiting the WMM complex (PubMed:27602518), Involved in random X inactivation mediated by Xist RNA: acts by binding Xist RNA and recruiting the WMM complex, which mediates m6A methylation, leading to target YTHDC1 reader on Xist RNA and promoting transcription repression activity of Xist (PubMed:27602518), Required for the development of multiple tissues, such as the maintenance of the homeostasis of long-term hematopoietic stem cells and for megakaryocyte (MK) and B-cell differentiation (By similarity), Regulates megakaryocyte differentiation by regulating alternative splicing of genes important for megakaryocyte differentiation; probably regulates alternative splicing via m6A regulation (PubMed:26575292), Required for placental vascular branching morphogenesis and embryonic development of the heart and spleen (By similarity), Acts as a regulator of thrombopoietin response in hematopoietic stem cells by regulating alternative splicing of MPL (By similarity), May also function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing (PubMed:17001072, PubMed:19786495), High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing (PubMed:17001072, PubMed:19786495), May be implicated in HOX gene regulation (PubMed:11344311)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RRM Spen family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRTAGRDPVPRRSPRWRRAVPLCETSAGRRVTQLRGDDLRRPATMKGKERSPVKAKRSRGGEDSTSRGERSKKLGGSGGSNGSSSGKTDSGGGSRRSLHLDKSSSRGGSREYDTGGGSSSSRLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGAEYKTLKISELGSQLSDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLYDRPLKIEAVYVSRRRSRSPLDKDTYPPSASVVGASVGGHRHPPGGGGGQRSLSPGGAALGYRDYRLQQLALGRLPPPPPPPLPRDLERERDYPFYERVRPAYSLEPRVGAGAGAAPFREVDEISPEDDQRANRTLFLGNLDITVTESDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKFENLDMSHRAKLAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTIRTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPLPLTHYELVTDAFGHRAPDPLRGARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSTRTAATSVPAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDRPRKRHCAPSPDRSPELSSSRDRYNSDNDRSSRLLLERPSPIRDRRGSLEKSQGDKRDRKNSASAERDRKHRTTAPTEGKSPLKKEDRSDGSAPSTSTASSKLKSPSQKQDGGTAPVASASPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQPKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSAASDTATSTQRPLRNLVSYLKQKQAAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVRGFGFQIGVRYENKKRENLALTLL", "length": 977, "molWeight": 107189, "crc64": "FB26AFE246E40282", "md5": "7FA24D20CEB3FD34BF6AE25CEB0CD334"}}
{"primaryAccession": "Q96TA2", "text": "This is ATP-dependent zinc metalloprotease YME1L1 protein, from Human, contains 773 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96TA2", "organism_name": "Human", "protein_name": "ATP-dependent zinc metalloprotease YME1L1", "length": 773, "firstPublicDate": "2004-04-13", "FUNCTION": "ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region (PubMed:26923599, PubMed:27786171), Plays an important role in regulating mitochondrial morphology and function by cleaving OPA1 at position S2, giving rise to a form of OPA1 that promotes maintenance of normal mitochondrial structure and mitochondrial protein metabolism (PubMed:18076378, PubMed:26923599, PubMed:27495975), Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins (PubMed:22262461), Required for normal, constitutive degradation of PRELID1 (PubMed:27495975), Catalyzes the degradation of OMA1 in response to membrane depolarization (PubMed:26923599), Required to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1) (PubMed:22262461)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "In the C-terminal section; belongs to the peptidase M41 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFSDFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRDLGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSCLYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFLLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR", "length": 773, "molWeight": 86455, "crc64": "FB77990F4D7B3A58", "md5": "30C51D4B0F74B73140F21395DDF683CF"}}
{"primaryAccession": "Q96VH5", "text": "This is MICOS complex subunit MIC10 protein, from Baker's yeast, contains 97 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96VH5", "organism_name": "Baker's yeast", "protein_name": "MICOS complex subunit MIC10", "length": 97, "firstPublicDate": "2004-08-31", "FUNCTION": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MICOS complex subunit Mic10 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSEQAQTQQPAKSTPSKDSNKNGSSVSTILDTKWDIVLSNMLVKTAMGFGVGVFTSVLFFKRRAFPVWLGIGFGVGRGYAEGDAIFRSSAGLRSSKV", "length": 97, "molWeight": 10408, "crc64": "D6C214612BD35E26", "md5": "48573B3E8024080BC0B286B9269328DA"}}
{"primaryAccession": "Q99109", "text": "This is Repellent protein 1 protein, from Corn smut fungus, contains 652 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99109", "organism_name": "Corn smut fungus", "protein_name": "Repellent protein 1", "length": 652, "firstPublicDate": "2005-06-21", "FUNCTION": "Water-repellent structural protein required for surface hydrophobicity and formation of aerial hyphae during filamentous growth", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPSKIALSISVLTAALGMVSAAPHYEYKSYNAGHNVESVVENKLVDASDLTLGVDILKRTDYSACKKYVSSYNAGYNVYSINENKLIDLSDATVKLSLLTNNGRPVKTWNKAPRYCLEYIKSYNGGHNVIIDNENKLIDLSGLNLGIDILKRKAPEFSYYNPGHNVKSTTENKLVDASDLLANVNILSKRGDKYSYYNGGYNVESDTENKLIDLSGLLANIDILKKRTGSQYSYYNGGHNVESTNENKLVDASDLLANVDILKKRGDKYTYYNGGHNIESTNENKLIDLSDLTANVGVLDDVHVNIGLLDKRTDKYSYYDGGHNIELTNENKLIDLSDLLANVDVLKKRTDKFSYYNGGHNVESDTQNKLIDVSHLTAIVNALSKRTDKYSYYNGGHNVESTNENKLIDLSDLTALVNVLSKRSLKGYGSKIHARDISEELYRRTNADEDCTCVKKSKPTPPKQTVTKPSADCDAPPAVTPKPKPSTKPSPSPTTPPPSKDTSKPTTKPEPKPQPSDKPEPKPSDKPEPKPSDKPEPKPSDKPEPTPSPKPTPPKVTCGTDEVYVDEGHNVVSKNSNKLLDLSNISINIGILDGLFGGKKSKEVAADSTCTSKQGCCVSKSVYYYNGGNNVQSSNENSGIDLSGLNLGLDIL", "length": 652, "molWeight": 71374, "crc64": "07B96277A2E496AB", "md5": "961F5E70EA1A6A1B4E21D91A36CEA9C6"}}
{"primaryAccession": "Q99549", "text": "This is M-phase phosphoprotein 8 protein, from Human, contains 860 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99549", "organism_name": "Human", "protein_name": "M-phase phosphoprotein 8", "length": 860, "firstPublicDate": "2000-05-30", "FUNCTION": "Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression (PubMed:20871592, PubMed:26022416), Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2 (PubMed:26022416, PubMed:28581500), Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene (PubMed:20871592), Mediates down-regulation of CDH1 expression (PubMed:20871592), Also represses L1 retrotransposons in collaboration with MORC2 and, probably, SETDB1, the silencing is dependent of repressive epigenetic modifications, such as H3K9me3 mark, Silencing events often occur within introns of transcriptionally active genes, and lead to the down-regulation of host gene expression (PubMed:29211708), The HUSH complex is also involved in the silencing of unintegrated retroviral DNA by being recruited by ZNF638: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed (PubMed:30487602)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEQVAEGARVTAVPVSAADSTEELAEVEEGVGVVGEDNDAAARGAEAFGDSEEDGEDVFEVEKILDMKTEGGKVLYKVRWKGYTSDDDTWEPEIHLEDCKEVLLEFRKKIAENKAKAVRKDIQRLSLNNDIFEANSDSDQQSETKEDTSPKKKKKKLRQREEKSPDDLKKKKAKAGKLKDKSKPDLESSLESLVFDLRTKKRISEAKEELKESKKPKKDEVKETKELKKVKKGEIRDLKTKTREDPKENRKTKKEKFVESQVESESSVLNDSPFPEDDSEGLHSDSREEKQNTKSARERAGQDMGLEHGFEKPLDSAMSAEEDTDVRGRRKKKTPRKAEDTRENRKLENKNAFLEKKTVPKKQRNQDRSKSAAELEKLMPVSAQTPKGRRLSGEERGLWSTDSAEEDKETKRNESKEKYQKRHDSDKEEKGRKEPKGLKTLKEIRNAFDLFKLTPEEKNDVSENNRKREEIPLDFKTIDDHKTKENKQSLKERRNTRDETDTWAYIAAEGDQEVLDSVCQADENSDGRQQILSLGMDLQLEWMKLEDFQKHLDGKDENFAATDAIPSNVLRDAVKNGDYITVKVALNSNEEYNLDQEDSSGMTLVMLAAAGGQDDLLRLLITKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAFVNVQQSNGETALMKACKRGNSDIVRLVIECGADCNILSKHQNSALHFAKQSNNVLVYDLLKNHLETLSRVAEETIKDYFEARLALLEPVFPIACHRLCEGPDFSTDFNYKPPQNIPEGSGILLFIFHANFLGKEVIARLCGPCSVQAVVLNDKFQLPVFLDSHFVYSFSPVAGPNKLFIRLTEAPSAKVKLLIGAYRVQLQ", "length": 860, "molWeight": 97182, "crc64": "DD75D14C3DBF5E95", "md5": "E26E1CAE69E3B129D97C7231BA0C5587"}}
{"primaryAccession": "Q99638", "text": "This is Cell cycle checkpoint control protein RAD9A protein, from Human, contains 391 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99638", "organism_name": "Human", "protein_name": "Cell cycle checkpoint control protein RAD9A", "length": 391, "firstPublicDate": "2006-03-07", "FUNCTION": "Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair, The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex, Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER), The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates, The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase, RAD9A possesses 3'->5' double stranded DNA exonuclease activity, Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the rad9 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKCLVTGGNVKVLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQYQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQPVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSEEEDEAEPSTVPGTPPPKKFRSLFFGSILAPVRSPQGPSPVLAEDSEGEG", "length": 391, "molWeight": 42547, "crc64": "4D4D6D4C6E1057D3", "md5": "57B7390F7B5B0FF8F0B61B95FD9CB31E"}}
{"primaryAccession": "Q99714", "text": "This is 3-hydroxyacyl-CoA dehydrogenase type-2 protein, from Human, contains 261 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99714", "organism_name": "Human", "protein_name": "3-hydroxyacyl-CoA dehydrogenase type-2", "length": 261, "firstPublicDate": "1997-11-01", "FUNCTION": "In addition to mitochondrial dehydrogenase activity, moonlights as a component of mitochondrial ribonuclease P, a complex that cleaves tRNA molecules in their 5'-ends (PubMed:18984158, PubMed:24549042, PubMed:25925575, PubMed:26950678, PubMed:28888424), Together with TRMT10C/MRPP1, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity (PubMed:23042678, PubMed:29040705), The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; HSD17B10/MRPP2 acting as a non-catalytic subunit (PubMed:23042678, PubMed:25925575, PubMed:28888424), The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3'-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme (PubMed:29040705), Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the short-chain dehydrogenases/reductases (SDR) family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLDGAIRMQP", "length": 261, "molWeight": 26923, "crc64": "9E74F242E3E6FEF1", "md5": "79DCF3868AEAD47E25C51B914768FD40"}}
{"primaryAccession": "Q99732", "text": "This is Lipopolysaccharide-induced tumor necrosis factor-alpha factor protein, from Human, contains 161 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99732", "organism_name": "Human", "protein_name": "Lipopolysaccharide-induced tumor necrosis factor-alpha factor", "length": 161, "firstPublicDate": "2000-05-30", "FUNCTION": "Plays a role in endosomal protein trafficking and in targeting proteins for lysosomal degradation (PubMed:23166352), Plays a role in targeting endocytosed EGFR and ERGG3 for lysosomal degradation, and thereby helps down-regulate downstream signaling cascades (PubMed:23166352), Helps recruit the ESCRT complex components TSG101, HGS and STAM to cytoplasmic membranes (PubMed:23166352), Probably plays a role in regulating protein degradation via its interaction with NEDD4 (PubMed:15776429), May also contribute to the regulation of gene expression in the nucleus (PubMed:10200294, PubMed:15793005), Binds DNA (in vitro) and may play a synergistic role with STAT6 in the nucleus in regulating the expression of various cytokines (PubMed:15793005), May regulate the expression of numerous cytokines, such as TNF, CCL2, CCL5, CXCL1, IL1A and IL10 (PubMed:10200294, PubMed:15793005)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the CDIP1/LITAF family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSVPGPYQAATGPSSAPSAPPSYEETVAVNSYYPTPPAPMPGPTTGLVTGPDGKGMNPPSYYTQPAPIPNNNPITVQTVYVQHPITFLDRPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLGCIAGCCFIPFCVDALQDVDHYCPNCRALLGTYKRL", "length": 161, "molWeight": 17107, "crc64": "08D15BF1FDCA16F0", "md5": "81A1AF29718BF54DE61FDEE58F22DA5F"}}
{"primaryAccession": "Q99788", "text": "This is Chemerin-like receptor 1 protein, from Human, contains 373 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99788", "organism_name": "Human", "protein_name": "Chemerin-like receptor 1", "length": 373, "firstPublicDate": "1998-07-15", "FUNCTION": "(Microbial infection) Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the chemokine-like receptor (CMKLR) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRMEDEDYNTSISYGDEYPDYLDSIVVLEDLSPLEARVTRIFLVVVYSIVCFLGILGNGLVIIIATFKMKKTVNMVWFLNLAVADFLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTIISSDRCISVLLPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHGKISCFNNFSLSTPGSSSWPTHSQMDPVGYSRHMVVTVTRFLCGFLVPVLIITACYLTIVCKLQRNRLAKTKKPFKIIVTIIITFFLCWCPYHTLNLLELHHTAMPGSVFSLGLPLATALAIANSCMNPILYVFMGQDFKKFKVALFSRLVNALSEDTGHSSYPSHRSFTKMSSMNERTSMNERETGML", "length": 373, "molWeight": 42322, "crc64": "5244B9738EC93834", "md5": "247DDC27C78E8F69FA6D97744DAC8F16"}}
{"primaryAccession": "Q99871", "text": "This is HAUS augmin-like complex subunit 7 protein, from Human, contains 358 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99871", "organism_name": "Human", "protein_name": "HAUS augmin-like complex subunit 7", "length": 358, "firstPublicDate": "1997-11-01", "FUNCTION": "Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the HAUS7 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAGQDAGCGRGGDDYSEDEGDSSVSRAAVEVFGKLKDLNCPFLEGLYITEPKTIQELLCSPSEYRLEILEWMCTRVWPSLQDRFSSLKGVPTEVKIQEMTKLGHELMLCAPDDQELLKGCACAQKQLHFMDQLLDTIRSLTIGCSSCSSLMEHFEDTREKNEALLGELFSSPHLQMLLNPECDPWPLDMQPLLNKQSDDWQWASASAKSEEEEKLAELARQLQESAAKLHALRTEYFAQHEQGAAAGAADISTLDQKLRLVTSDFHQLILAFLQVYDDELGECCQRPGPDLHPCGPIIQATHQNLTSYSQLLQVVMAVADTSAKAVETVKKQQGEQICWGGSSSVMSLATKMNELMEK", "length": 358, "molWeight": 39794, "crc64": "EFD0264BD6608F0F", "md5": "CAECF05EB83AE330ED99394AEAD25220"}}
{"primaryAccession": "Q99J87", "text": "This is ATP-dependent RNA helicase DHX58 protein, from Mouse, contains 678 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99J87", "organism_name": "Mouse", "protein_name": "ATP-dependent RNA helicase DHX58", "length": 678, "firstPublicDate": "2004-07-19", "FUNCTION": "Acts as a regulator of RIGI and IFIH1/MDA5 mediated antiviral signaling, Cannot initiate antiviral signaling as it lacks the CARD domain required for activating MAVS/IPS1-dependent signaling events, Can have both negative and positive regulatory functions related to RIGI and IFIH1/MDA5 signaling and this role in regulating signaling may be complex and could probably depend on characteristics of the infecting virus or target cells, or both, Its inhibitory action on RIG-I signaling may involve the following mechanisms: competition with RIGI for binding to the viral RNA, binding to RIGI and inhibiting its dimerization and interaction with MAVS/IPS1, competing with IKBKE in its binding to MAVS/IPS1 thereby inhibiting activation of interferon regulatory factor 3 (IRF3), Its positive regulatory role may involve unwinding or stripping nucleoproteins of viral RNA thereby facilitating their recognition by RIGI and IFIH1/MDA5, Involved in the innate immune response to various RNA viruses and some DNA viruses such as poxviruses, and also to the bacterial pathogen Listeria monocytogenes, Can bind both ssRNA and dsRNA, with a higher affinity for dsRNA, Shows a preference to 5'-triphosphorylated RNA, although it can recognize RNA lacking a 5'-triphosphate", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the helicase family, RLR subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MELRPYQWEVILPALEGKNIIIWLPTGAGKTRAAAFVAKRHLETVDRGKVVVLVNRVHLVSQHAEEFRRMLDKHWTVTTLSGDMGSRAGFGLMARSHDLLICTAELLQLALNSSEEDEHVELREFSLIVVDECHHTHKDTVYNTILSRYLEQKLKKAEPLPQVLGLTASPGTGGATKLQGAIDHILQLCANLDTCHIMSPKNCYSQLLMHNPKPCKQYDLCQRRAQDPFGDLIKKLMNQIHQQLEMPDLKQQFGTQMYEQQVVQLCKDAAEAGLQEQRVYALHLRRYNDALFIHDTVRARDALDMLQDFYDRERTTKTQMVRAESWLLKLFDDHKNVLGQLAARGPENPKLEMLERILLKQFGSPGHTRGIIFTRTRQTASSLLLWLRQQPCLQTVGIKPQMLIGAGNTSQSTHMTQKDQQEVIQEFRDGILSLLVATSVAEEGLDIAQCNVVVRYGLLTNEISMVQARGRARAGQSVYSFLATEGSREMKRELTNEALEVLMEKAVAAVQKMDPDEFKAKIRDLQQASLVKRAARAAHREIQQGQFLPEHVQLLCINCMVAVGYGSDLRKVEGTHHVNVNPNFSVYYTTSQNPVVINKVFKDWRPGGTIRCSNCGEVWGFQMIYKSVTLPVLKIGSILLETPRGKIQAKKWSRVPFSIPVFDILQDCTQSLSELSLD", "length": 678, "molWeight": 76709, "crc64": "D907A30E3AD376A8", "md5": "FE15DCEE37CBA5EC4ACEB17C9D0ADAA3"}}
{"primaryAccession": "Q99JX3", "text": "This is Golgi reassembly-stacking protein 2 protein, from Mouse, contains 451 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99JX3", "organism_name": "Mouse", "protein_name": "Golgi reassembly-stacking protein 2", "length": 451, "firstPublicDate": "2004-08-16", "FUNCTION": "Key structural protein of the Golgi apparatus (PubMed:32573693), The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon (PubMed:32573693), Acting in concert with GORASP1/GRASP65, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks (PubMed:32573693), However, other studies suggest that GORASP2 plays a role in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis (By similarity), May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA (By similarity), Required for normal acrosome formation during spermiogenesis and normal male fertility, probably by promoting colocalization of JAM2 and JAM3 at contact sites between germ cells and Sertoli cells (PubMed:28617811), Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane (By similarity)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GORASP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGSSQSVEIPGGGTEGYHVLRVQENSPGHRAGLEPFFDFIVSINGSRLNKDNDTLKDLLKANVEKPVKMLIYSSKTLELREASVTPSNLWGGQGLLGVSIRFCSFDGANENVWHVLEVESNSPAALAGLRPHSDYIIGADTVMNESEDLFSLIETHEAKPLKLYVYNTDTDNCREVIITPNSAWGGEGSLGCGIGYGYLHRIPTRPFEEGKKISLPGQMTGTPITPLKDGFTEVQLSSVSPPSLSPPGTTGVEQSLSGLSISSAPPAVSNVLSTGVPTVPLLPPQVNQSLASMPPMNPATTLPSLMPLSAGLPSLPNLPSLSNFNLPAPHIMPGVGLPELGSPGLPPLPSLPPRNLPGIAPLPMLSDFLPSFPLVPEGSSAASAGEPLSSLPAMGPPSDPVMTTAKADASSLTVDVTSPASKVPTTVEDRVSDCTPAVEKPVSDADASEPS", "length": 451, "molWeight": 47038, "crc64": "7E37234E827B459A", "md5": "E56170C9C61EDE13BB2DDC9BA2E4105C"}}
{"primaryAccession": "Q99K48", "text": "This is Non-POU domain-containing octamer-binding protein protein, from Mouse, contains 473 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99K48", "organism_name": "Mouse", "protein_name": "Non-POU domain-containing octamer-binding protein", "length": 473, "firstPublicDate": "2005-06-07", "FUNCTION": "DNA- and RNA binding protein, involved in several nuclear processes, Binds the conventional octamer sequence in double-stranded DNA (PubMed:8355702), Also binds single-stranded DNA and RNA at a site independent of the duplex site (By similarity), Involved in pre-mRNA splicing, probably as a heterodimer with SFPQ (By similarity), Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b (By similarity), Together with PSPC1, required for the formation of nuclear paraspeckles (By similarity), The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs (By similarity), The SFPQ-NONO heteromer may be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1 (By similarity), The SFPQ-NONO heteromer may be involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination and may stabilize paired DNA ends (By similarity), In vitro, the complex strongly stimulates DNA end joining, binds directly to the DNA substrates and cooperates with the Ku70/G22P1-Ku80/XRCC5 (Ku) dimer to establish a functional preligation complex (By similarity), NONO is involved in transcriptional regulation (By similarity), The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity (By similarity), NONO binds to an enhancer element in long terminal repeats of endogenous intracisternal A particles (IAPs) and activates transcription (PubMed:9001221), Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer (PubMed:22966205), Important for the functional organization of GABAergic synapses (PubMed:26571461), Plays a specific and important role in the regulation of synaptic RNAs and GPHN/gephyrin scaffold structure, through the regulation of GABRA2 transcript (PubMed:26571461), Plays a key role during neuronal differentiation by recruiting TET1 to genomic loci and thereby regulating 5-hydroxymethylcytosine levels (PubMed:32286661), Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQSNKAFNLEKQNHTPRKHHQHHHQQHHQQQQQQQQQQPPPPIPANGQQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPPGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRPAPGAEFAPNKRRRY", "length": 473, "molWeight": 54541, "crc64": "F65E6AE25D471A38", "md5": "6ED419ECA99427A13F0BC1D5501382A0"}}
{"primaryAccession": "Q99KK2", "text": "This is N-acylneuraminate cytidylyltransferase protein, from Mouse, contains 432 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99KK2", "organism_name": "Mouse", "protein_name": "N-acylneuraminate cytidylyltransferase", "length": 432, "firstPublicDate": "2005-02-01", "FUNCTION": "Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid, Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CMP-NeuNAc synthase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDALEKGAVTSGPAPRGRPSRGRPPKLQRSRGAGRGLEKPPHLAALVLARGGSKGIPLKNIKRLAGVPLIGWVLRAALDAGVFQSVWVSTDHDEIENVAKQFGAQVHRRSSETSKDSSTSLDAIVEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHQFRWSEIQKGVREVTEPLNLNPAKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEMRAEHSVDIDVDIDWPIAEQRVLRFGYFGKEKLKEIKLLVCNIDGCLTNGHIYVSGDQKEIISYDVKDAIGISLLKKSGIEVRLISERACSKQTLSALKLDCKTEVSVSDKLATVDEWRKEMGLCWKEVAYLGNEVSDEECLKRVGLSAVPADACSGAQKAVGYICKCSGGRGAIREFAEHIFLLIEKVNNSCQK", "length": 432, "molWeight": 48058, "crc64": "BF7295535E7F6CE5", "md5": "9A310F2BB3A7BC6A8776AC84EEA8F14E"}}
{"primaryAccession": "Q99LQ4", "text": "This is Small vasohibin-binding protein protein, from Mouse, contains 66 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99LQ4", "organism_name": "Mouse", "protein_name": "Small vasohibin-binding protein", "length": 66, "firstPublicDate": "2006-05-02", "FUNCTION": "Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin (PubMed:29146868, PubMed:31363758, PubMed:35482892), Also required to enhance the solubility and secretion of VASH1 and VASH2 (By similarity), Plays a role in axon and excitatory synapse formation (PubMed:31235911)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the SVBP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDPPARKEKSKVKEPAFRVEKAKQKSAQQELKQRQRAEIYALNRVMTELEQQQFDEFCKQMQPPGE", "length": 66, "molWeight": 7836, "crc64": "9C0F238316F33CC8", "md5": "61CBECF86DC30B103AC9B1561A5AE9DA"}}
{"primaryAccession": "Q99ML8", "text": "This is Urocortin-2 protein, from Mouse, contains 113 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99ML8", "organism_name": "Mouse", "protein_name": "Urocortin-2", "length": 113, "firstPublicDate": "2002-05-10", "FUNCTION": "Suppresses food intake, delays gastric emptying and decreases heat-induced edema, Might represent an endogenous ligand for maintaining homeostasis after stress (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMTRWALVVFVVLMLDRILFVPGTPIPTFQLLPQNSLETTPSSVTSESSSGTTTGPSASWSNSKASPYLDTRVILSLDVPIGLLRILLEQARYKAARNQAATNAQILAHVGRR", "length": 113, "molWeight": 12310, "crc64": "9C55EB416C7D5B25", "md5": "C9B054469B6298731A35DDE3E3C70B4E"}}
{"primaryAccession": "Q99MQ1", "text": "This is Protein bicaudal C homolog 1 protein, from Mouse, contains 977 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99MQ1", "organism_name": "Mouse", "protein_name": "Protein bicaudal C homolog 1", "length": 977, "firstPublicDate": "2006-12-12", "FUNCTION": "Putative RNA-binding protein, May be involved in regulating gene expression during embryonic development", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the BicC family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASQSEPGYLAAAQSDPGSNSERSTDSPVAGSEDDLVAAAPLLHSPEWSEERFRVDRKKLEAMLQAAAEGKGRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEDTGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARARIRELLPLVLMFELPIAGILQPVPDPNTPSIQHISQTYSVSVSFKQRSRMYGATVTVRGSQNNTNAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNVKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEDIEVDPQVIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVSIATSLSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSATPNSLLNALNTSVSPLQSSSSGTPSPTLWAPPIANTASATGFSTIPHLMLPSTAQATLTNILLSGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKNISASINGHVQPANMKYGPLSTSSLGEKVLSSNHGDPSMQTAGPEQASPKSNSVEGCNDAFVEVGMPRSPSHSGNAGDLKQMLGASKVSCAKRQTVELLQGTKNSHLHGTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQKSERARLASQPTYVHMQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTAYEGSSLSLSRSSSREHLASGSESDNWRDRNGIGPMGHSEFSAPIGSPKRKQNKSREHYLSSSNYMDCISSLTGSNGCNLNSCFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELSKNRRKLFEPPNASCTSFLEGGASGRLPRQYHSDIASVSGRW", "length": 977, "molWeight": 105037, "crc64": "3A5A7B7F2CA84918", "md5": "3D36A10FAEE667208272D7B0BB566D25"}}
{"primaryAccession": "Q99MS4", "text": "This is Serine protease 29 protein, from Mouse, contains 279 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99MS4", "organism_name": "Mouse", "protein_name": "Serine protease 29", "length": 279, "firstPublicDate": "2008-09-02", "FUNCTION": "Involved in embryo hatching and implantation", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLIQLCLTLFFLGCSIAGTPAPGPEDVLMGIVGGHSAPQGKWPWQVSLRIYRYYWAFWVHNCGGSIIHPQWVLTAAHCIRERDADPSVFRIRVGEAYLYGGKELLSVSRVIIHPDFVHAGLGSDVALLQLAVSVQSFPNVKPVKLPSESLEVTKKDVCWVTGWGAVSTHRSLPPPYRLQQVQVKIIDNSLCEEMYHNATRHRNRGQKLILKDMLCAGNQGQDSCYGDSGGPLVCNVTGSWTLVGVVSWGYGCALRDFPGVYARVQSFLPWITQQMQRFS", "length": 279, "molWeight": 30986, "crc64": "81C43A59935244D7", "md5": "90BAD7FCB5870C70D6F1216DE2496261"}}
{"primaryAccession": "Q99MV2", "text": "This is Testis-expressed protein 19.1 protein, from Mouse, contains 351 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99MV2", "organism_name": "Mouse", "protein_name": "Testis-expressed protein 19.1", "length": 351, "firstPublicDate": "2008-03-18", "FUNCTION": "Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and preventing their mobilization (PubMed:18802469, PubMed:21103378, PubMed:23364048, PubMed:23674551, PubMed:28254886), With its paralog, Tex19,2, collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins, Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements (PubMed:28254886), Also during spermatogenesis, promotes, with UBR2, SPO11-dependent meiotic recombination (PubMed:28708824), Interacts with LINE-1 retrotransposon encoded LIRE1, stimulates LIRE1 polyubiquitination, mediated by UBR2, and degradation, inhibiting LINE-1 retrotransposon mobilization (PubMed:28806172)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MCPPVSVRHGARGMSCLYEAWLYHLVHGEQTKICFACFKAAFLLNKLYLEMGDWQEEEEEEEEEDADLLEYLSESESESEQEPGPEQDAWRGLGSLYVPQSVSEGSGVLLPTPVWTQGILFSIFVPTELFPQEAVPLDLGPEDAEWTQALPWRLDGLFPCSHQLIPPLTWWDIFDVMPSPGQPVLLELRCHWPLDQTVAQSWLQDQKFVLLLDSVQSRCHLLSMRVRWVVRTQVQHWQVLLDPGEMWVAHFRKEVGQHGLYHQSLNPWRLSILTASELGMELLPATCYLWNKGFWVGSFLPWHINMPETWSWEPGERLFITDATICGTDYHLAQSFLDSHPTPHPLLTLTP", "length": 351, "molWeight": 40401, "crc64": "0DD9C083F70573C1", "md5": "0A31DC2D3605350E27FB7BB8BD39EB52"}}
{"primaryAccession": "Q99NB1", "text": "This is Acetyl-coenzyme A synthetase 2-like, mitochondrial protein, from Mouse, contains 682 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99NB1", "organism_name": "Mouse", "protein_name": "Acetyl-coenzyme A synthetase 2-like, mitochondrial", "length": 682, "firstPublicDate": "2003-04-23", "FUNCTION": "Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids (PubMed:11150295, PubMed:16790548), Acetate is the preferred substrate (PubMed:11150295, PubMed:16790548), Can also utilize propionate with a much lower affinity (PubMed:11150295), Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (PubMed:11150295), Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (PubMed:19187775)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the ATP-dependent AMP-binding enzyme family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAARSLGSGVGRLLRGLQGRSGQSGWSLSVSRSTATRLPGCVPAAAQPGSYPALSAQAAQEPAAFWGPLARDTLVWDTPYHTVWDCDFRTGKIGWFLGGQLNVSVNCLDQHVQKSPETIALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAIHTVVFAGFSAESLAGRINDAKCKAVITFNQGLRGGRVVELKKIVDEAVKSCPTVQHVLVAHRTDTKVPMGSLDIPLEQEMAKEAPVCTPESMSSEDMLFMLYTSGSTGTPKGLVHTQAGYLLYAAMTHKLVFDYQPGDVFGCVADIGWITGHSYVVYGPLCNGATTVLFESTPVYPDAGRYWETVQRLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINHEAWEWLHKVVGDGRCTLVDTWWQTETGGICIAPRPSEDGAEILPGMAMRPFFGIVPVLMDEKGNVLEGGDVSGALCISQAWPGMARTIYGDHQRFVDAYFRAYPGYYFTGDGAHRTEGGYYQITGRMDDVINISGHRLGTAEIEDAMADHPAVPETAVIGYPHDIKGEAAFAFIVLKDNISDENMVVNELKLSVATKIAKYAVPDQILVVKRLPKTRSGKVMRRLLRKIITSRGQDLGDTTTLEDPSVITEILSAFQKYEEQRAATN", "length": 682, "molWeight": 74623, "crc64": "1B21981D29F9C8E7", "md5": "D39EF1861F9D838626033086959C2DA9"}}
{"primaryAccession": "Q99P30", "text": "This is Peroxisomal coenzyme A diphosphatase NUDT7 protein, from Mouse, contains 236 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99P30", "organism_name": "Mouse", "protein_name": "Peroxisomal coenzyme A diphosphatase NUDT7", "length": 236, "firstPublicDate": "2005-07-19", "FUNCTION": "Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (PubMed:11415433, PubMed:18799520, PubMed:29378847), Cleaves CoA, CoA esters and oxidized CoA with similar efficiencies (PubMed:11415433), Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs (PubMed:18799520), Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester (PubMed:18799520), May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand (PubMed:18799520), Does not play a role in U8 snoRNA decapping activity (PubMed:21070968), Binds U8 snoRNA (PubMed:21070968), Exhibits decapping activity towards dpCoA-capped RNAs in vitro (PubMed:32432673)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the Nudix hydrolase family, PCD1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRPCGLPEPVRNNLIDDAKARLRKSDVGTRYSHLSSNKFSVLVPLLARGGKLYLMFTVRSDKLKREPGEVCFPGGKRDPVDTDDTATALREAQEEVGLHPHQVEVVSHLVPYVFDNDALVTPVVGFLDHNFQAQPNADEVKEVFFVPLDYFLHPQVYYQKQITQSGRDFIMHCFEYKDPETGVNYLIQGMTSKLAVLVALIILEQSPAFKIDFDLHDLIPSCERTFLWRYSLSKL", "length": 236, "molWeight": 26857, "crc64": "37A22A9135F8F9ED", "md5": "105267C5269401B3525C7238ABC3C4B0"}}
{"primaryAccession": "Q99PQ1", "text": "This is Tripartite motif-containing protein 12A protein, from Mouse, contains 284 amino acids, has 1 RING-type Zinc finger, has 1 B box-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [15, 59], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [91, 132], "description": "B box-type", "keyword_description": "Zinc finger", "textural_description": "B box-type Zinc finger"}], "meta_data": {"primaryAccession": "Q99PQ1", "organism_name": "Mouse", "protein_name": "Tripartite motif-containing protein 12A", "length": 284, "firstPublicDate": "2004-12-07", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TRIM/RBCC family", "domain_description": {"RING-type Zinc finger": 1, "B box-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASQFMKNLKEEVTCPVCLNLMVKPVSADCGHTFCQGCITLYFESIKCDKKVFICPVCRISYQFSNLRPNRNVANIVERLKMFKPSPEEEQKVFNCARHGKKLQLFCRKDMMAICWLCERSQEHRGHKTALIEEVAQEYKEQLQVVLQRLMADKKKFENWKDDLQKDRTYWENQIQKDVQNVRSEFKRMRDIMDSEEKKELQKLRQEKEDILNNLAESESEHAQQSKLLEDFISDVEHQLQCSDIEILQVRLQDVPGSESQKAWKPLPFLSAAVVFLVMTVSSS", "length": 284, "molWeight": 33320, "crc64": "B551B4C4D9CFF527", "md5": "16DC088D3E41BC1B5ED53235A35B2E7F"}}
{"primaryAccession": "Q9BQ83", "text": "This is Structure-specific endonuclease subunit SLX1 protein, from Human, contains 275 amino acids, has 1 SLX1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [186, 238], "description": "SLX1-type", "keyword_description": "Zinc finger", "textural_description": "SLX1-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9BQ83", "organism_name": "Human", "protein_name": "Structure-specific endonuclease subunit SLX1", "length": 275, "firstPublicDate": "2008-04-29", "FUNCTION": "Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA, Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs), Resolves HJs by generating two pairs of ligatable, nicked duplex products", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SLX1 family", "domain_description": {"SLX1-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGPAGVAARPGRFFGVYLLYCLNPRYRGRVYVGFTVNTARRVQQHNGGRKKGGAWRTSGRGPWEMVLVVHGFPSSVAALRFEWAWQHPHASRRLAHVGPRLRGETAFAFHLRVLAHMLRAPPWARLPLTLRWVRPDLRQDLCLPPPPHVPLAFGPPPPQAPAPRRRAGPFDDAEPEPDQGDPGACCSLCAQTIQDEEGPLCCPHPGCLLRAHVICLAEEFLQEEPGQLLPLEGQCPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET", "length": 275, "molWeight": 30771, "crc64": "57DF055F2E59CF70", "md5": "6609542CF965F7B383C921F4A306AECA"}}
{"primaryAccession": "Q9BQA5", "text": "This is Histone H4 transcription factor protein, from Human, contains 517 amino acids, has 8 C2H2-type Zinc finger, has 1 C2H2-type 4; degenerate Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [15, 39], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [129, 153], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [169, 193], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [199, 221], "description": "C2H2-type 4; degenerate", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 4; degenerate Zinc finger"}, {"location": [229, 251], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [255, 278], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [284, 306], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [312, 337], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [345, 368], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9BQA5", "organism_name": "Human", "protein_name": "Histone H4 transcription factor", "length": 517, "firstPublicDate": "2004-07-19", "FUNCTION": "Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter, Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT, Also activates transcription of the ATM and PRKDC genes, Autoregulates its expression by associating with its own promoter", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 8, "C2H2-type 4; degenerate Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPPPGKVPRKENLWLQCEWGSCSFVCSTMEKFFEHVTQHLQQHLHGSGEEEEEEEEDDPLEEEFSCLWQECGFCSLDSSADLIRHVYFHCYHTKLKQWGLQALQSQADLGPCILDFQSRNVIPDIPDHFLCLWEHCENSFDNPEWFYRHVEAHSLCCEYEAVGKDNPVVLCGWKGCTCTFKDRSKLREHLRSHTQEKVVACPTCGGMFANNTKFLDHIRRQTSLDQQHFQCSHCSKRFATERLLRDHMRNHVNHYKCPLCDMTCPLPSSLRNHMRFRHSEDRPFKCDCCDYSCKNLIDLQKHLDTHSEEPAYRCDFENCTFSARSLCSIKSHYRKVHEGDSEPRYKCHVCDKCFTRGNNLTVHLRKKHQFKWPSGHPRFRYKEHEDGYMRLQLVRYESVELTQQLLRQPQEGSGLGTSLNESSLQGIILETVPGEPGRKEEEEEGKGSEGTALSASQDNPSSVIHVVNQTNAQGQQEIVYYVLSEAPGEPPPAPEPPSGGIMEKLQGIAEEPEIQMV", "length": 517, "molWeight": 59678, "crc64": "2CE1910737B0B6EB", "md5": "37F010B002D38D31877104C5BF1BEEEE"}}
{"primaryAccession": "Q9BQB4", "text": "This is Sclerostin protein, from Human, contains 213 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BQB4", "organism_name": "Human", "protein_name": "Sclerostin", "length": 213, "firstPublicDate": "2002-03-05", "FUNCTION": "Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the sclerostin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQLPLALCLVCLLVHTAFRVVEGQGWQAFKNDATEIIPELGEYPEPPPELENNKTMNRAENGGRPPHHPFETKDVSEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGEAPRARKVRLVASCKCKRLTRFHNQSELKDFGTEAARPQKGRKPRPRARSAKANQAELENAY", "length": 213, "molWeight": 24031, "crc64": "30DBD55CE73D5BB2", "md5": "69CC8BA01D40E02CF7D88B00AAC276C0"}}
{"primaryAccession": "Q9BQQ3", "text": "This is Golgi reassembly-stacking protein 1 protein, from Human, contains 440 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BQQ3", "organism_name": "Human", "protein_name": "Golgi reassembly-stacking protein 1", "length": 440, "firstPublicDate": "2004-08-16", "FUNCTION": "Key structural protein of the Golgi apparatus (PubMed:33301566), The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon (PubMed:33301566), Acting in concert with GORASP2/GRASP55, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks (PubMed:33301566), However, other studies suggest that GORASP1 plays an important role in assembly and membrane stacking of the cisternae, and in the reassembly of Golgi stacks after breakdown during mitosis (By similarity), Caspase-mediated cleavage of GORASP1 is required for fragmentation of the Golgi during apoptosis (By similarity), Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes (PubMed:16489344), Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane (PubMed:21884936)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GORASP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGLGVSAEQPAGGAEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVVPSNMWGGQGLLGASVRFCSFRRASEQVWHVLDVEPSSPAALAGLRPYTDYVVGSDQILQESEDFFTLIESHEGKPLKLMVYNSKSDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPPSYHKKPPGTPPPSALPLGAPPPDALPPGPTPEDSPSLETGSRQSDYMEALLQAPGSSMEDPLPGPGSPSHSAPDPDGLPHFMETPLQPPPPVQRVMDPGFLDVSGISLLDNSNASVWPSLPSSTELTTTAVSTSGPEDICSSSSSHERGGEATWSGSEFEVSFLDSPGAQAQADHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPASTEGLDTGTEAEGLDSQAQISTTE", "length": 440, "molWeight": 46482, "crc64": "1187C0356E16CE00", "md5": "171B90C7CE6439EE904C763DC6B2AF22"}}
{"primaryAccession": "Q9BR76", "text": "This is Coronin-1B protein, from Human, contains 489 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BR76", "organism_name": "Human", "protein_name": "Coronin-1B", "length": 489, "firstPublicDate": "2002-05-27", "FUNCTION": "Regulates leading edge dynamics and cell motility in fibroblasts, May be involved in cytokinesis and signal transduction (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the WD repeat coronin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGRMENGDA", "length": 489, "molWeight": 54235, "crc64": "A6012FDA683ECB59", "md5": "3A79A1E3F0631C9282F7B314941A314D"}}
{"primaryAccession": "Q9BTP7", "text": "This is Fanconi anemia core complex-associated protein 24 protein, from Human, contains 215 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BTP7", "organism_name": "Human", "protein_name": "Fanconi anemia core complex-associated protein 24", "length": 215, "firstPublicDate": "2007-01-09", "FUNCTION": "Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA, Regulates FANCD2 monoubiquitination upon DNA damage, Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed, Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEKNPPDDTGPVHVPLGHIVANEKWRGSQLAQEMQGKIKLIFEDGLTPDFYLSNRCCILYVTEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQPR", "length": 215, "molWeight": 23897, "crc64": "2CADEFE1A4536D4E", "md5": "375AA6C458BD16CE0A75B20EF0F9080B"}}
{"primaryAccession": "Q9BUL9", "text": "This is Ribonuclease P protein subunit p25 protein, from Human, contains 199 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BUL9", "organism_name": "Human", "protein_name": "Ribonuclease P protein subunit p25", "length": 199, "firstPublicDate": "2006-05-30", "FUNCTION": "Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:12003489, PubMed:16723659, PubMed:30454648), Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone-like Alba family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MENFRKVRSEEAPAGCGAEGGGPGSGPFADLAPGAVHMRVKEGSKIRNLMAFATASMAQPATRAIVFSGCGRATTKTVTCAEILKRRLAGLHQVTRLRYRSVREVWQSLPPGPTQGQTPGEPAASLSVLKNVPGLAILLSKDALDPRQPGYQPPNPHPGPSSPPAAPASKRSLGEPAAGEGSAKRSQPEPGVADEDQTA", "length": 199, "molWeight": 20632, "crc64": "9A4494F0297B2A81", "md5": "1A9F496E00E2A35CC8D726BA2B66766A"}}
{"primaryAccession": "Q9BV35", "text": "This is Mitochondrial adenyl nucleotide antiporter SLC25A23 protein, from Human, contains 468 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BV35", "organism_name": "Human", "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A23", "length": 468, "firstPublicDate": "2008-02-05", "FUNCTION": "Electroneutral antiporter that mediates the transport of adenine nucleotides through the inner mitochondrial membrane, Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter, By regulating the mitochondrial matrix adenine nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenine nucleotide-dependent metabolic pathways (PubMed:15123600), Also acts as a regulator of mitochondrial calcium uptake and can probably transport trace amounts of other divalent metal cations in complex with ATP (PubMed:24430870, PubMed:28695448), In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides (PubMed:15123600)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRGSPGDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDADPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR", "length": 468, "molWeight": 52378, "crc64": "B2D66A4665C27174", "md5": "D28E303FFB7CE77CB0A818BD4B3D6881"}}
{"primaryAccession": "Q9BVJ6", "text": "This is U3 small nucleolar RNA-associated protein 14 homolog A protein, from Human, contains 771 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BVJ6", "organism_name": "Human", "protein_name": "U3 small nucleolar RNA-associated protein 14 homolog A", "length": 771, "firstPublicDate": "2005-07-05", "FUNCTION": "May be required for ribosome biogenesis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the UTP14 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTANRLAESLLALSQQEELADLPKDYLLSESEDEGDNDGERKHQKLLEAISSLDGKNRRKLAERSEASLKVSEFNVSSEGSGEKLVLADLLEPVKTSSSLATVKKQLSRVKSKKTVELPLNKEEIERIHREVAFNKTAQVLSKWDPVVLKNRQAEQLVFPLEKEEPAIAPIEHVLSGWKARTPLEQEIFNLLHKNKQPVTDPLLTPVEKASLRAMSLEEAKMRRAELQRARALQSYYEAKARREKKIKSKKYHKVVKKGKAKKALKEFEQLRKVNPAAALEELEKIEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLSKNKELTQKLQVASESEEEEGGTEDVEELLVPDVVNEVQMNADGPNPWMLRSCTSDTKEAATQEDPEQLPELEAHGVSESEGEERPVAEEEILLREFEERRSLRKRSELSQDAEPAGSQETKDSGSQEVLSELRVLSQKLKENHQSRKQKASSEGTIPQVQREEPAPEEEEPLLLQRPERVQTLEELEELGKEECFQNKELPRPVLEGQQSERTPNNRPDAPKEKKKKEQMIDLQNLLTTQSPSVKSLAVPTIEELEDEEERNHRQMIKEAFAGDDVIRDFLKEKREAVEASKPKDVDLTLPGWGEWGGVGLKPSAKKRRRFLIKAPEGPPRKDKNLPNVIINEKRNIHAAAHQVRVLPYPFTHHWQFERTIQTPIGSTWNTQRAFQKLTTPKVVTKPGHIINPIKAEDVGYRSSSRSDLSVIQRNPKRITTRHKKQLKKCSVD", "length": 771, "molWeight": 87978, "crc64": "DF82C264BA6486FE", "md5": "1A0712582B8BD5ABA9CDC5B6BA74D4BB"}}
{"primaryAccession": "Q9BVK8", "text": "This is BOS complex subunit TMEM147 protein, from Human, contains 224 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BVK8", "organism_name": "Human", "protein_name": "BOS complex subunit TMEM147", "length": 224, "firstPublicDate": "2007-01-09", "FUNCTION": "Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:32820719, PubMed:36261522), The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (PubMed:36261522), Also acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (PubMed:21056967), Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (PubMed:21056967), Regulates LBR localization to the nucleus inner membrane (PubMed:32694168)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the TMEM147 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTLFHFGNCFALAYFPYFITYKCSGLSEYNAFWKCVQAGVTYLFVQLCKMLFLATFFPTWEGGIYDFIGEFMKASVDVADLIGLNLVMSRNAGKGEYKIMVAALGWATAELIMSRCIPLWVGARGIEFDWKYIQMSIDSNISLVHYIVASAQVWMITRYDLYHTFRPAVLLLMFLSVYKAFVMETFVHLCSLGSWAALLARAVVTGLLALSTLALYVAVVNVHS", "length": 224, "molWeight": 25261, "crc64": "90122F32C34F16AE", "md5": "E227CC3F4D067845323F460DBF9179E5"}}
{"primaryAccession": "Q9BW62", "text": "This is Katanin p60 ATPase-containing subunit A-like 1 protein, from Human, contains 490 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BW62", "organism_name": "Human", "protein_name": "Katanin p60 ATPase-containing subunit A-like 1", "length": 490, "firstPublicDate": "2005-03-01", "FUNCTION": "Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility, Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity), Has microtubule-severing activity in vitro (PubMed:26929214)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the AAA ATPase family, Katanin p60 subunit A1 subfamily, A-like 1 sub-subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNLAEICDNAKKGREYALLGNYDSSMVYYQGVMQQIQRHCQSVRDPAIKGKWQQVRQELLEEYEQVKSIVSTLESFKIDKPPDFPVSCQDEPFRDPAVWPPPVPAEHRAPPQIRRPNREVRPLRKEMAGVGARGPVGRAHPISKSEKPSTSRDKDYRARGRDDKGRKNMQDGASDGEMPKFDGAGYDKDLVEALERDIVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAADLEKYEKWMVEFGSA", "length": 490, "molWeight": 55392, "crc64": "CB8E51A77E5CB487", "md5": "7291A75A3952303CE16676248906375E"}}
{"primaryAccession": "Q9BWW7", "text": "This is Transcriptional repressor scratch 1 protein, from Human, contains 348 amino acids, has 4 C2H2-type Zinc finger, has 1 C2H2-type 5; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [191, 213], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [222, 244], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [248, 270], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [276, 298], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [304, 327], "description": "C2H2-type 5; atypical", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 5; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9BWW7", "organism_name": "Human", "protein_name": "Transcriptional repressor scratch 1", "length": 348, "firstPublicDate": "2004-04-13", "FUNCTION": "Transcriptional repressor that binds E-box motif CAGGTG, Can modulate the action of basic helix-loop-helix (bHLH) transcription factors, critical for neuronal differentiation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the snail C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 4, "C2H2-type 5; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPRSFLVKKVKLDAFSSADLESAYGRARSDLGAPLHDKGYLSDYVGPSSVYDGDAEAALLKGPSPEPMYAAAVRGELGPAAAGSAPPPTPRPELATAAGGYINGDAAVSEGYAADAFFITDGRSRRKASNAGAAAAPSTASAAAPDGDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEARAGPGAAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLTHDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYESACFKGGAGGPAAPAPPQLSPVQA", "length": 348, "molWeight": 35554, "crc64": "D3BB51709C7795DA", "md5": "B38720F7B5F67AC69D3F249FB7256842"}}
{"primaryAccession": "Q9BX95", "text": "This is Sphingosine-1-phosphate phosphatase 1 protein, from Human, contains 441 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BX95", "organism_name": "Human", "protein_name": "Sphingosine-1-phosphate phosphatase 1", "length": 441, "firstPublicDate": "2003-10-10", "FUNCTION": "Specifically dephosphorylates sphingosine 1-phosphate (S1P), dihydro-S1P, and phyto-S1P, Does not act on ceramide 1-phosphate, lysophosphatidic acid or phosphatidic acid (PubMed:16782891), Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway (PubMed:12815058, PubMed:11756451, PubMed:16782891), Regulates the intracellular levels of the bioactive sphingolipid metabolite S1P that regulates diverse biological processes acting both as an extracellular receptor ligand or as an intracellular second messenger (PubMed:11756451, PubMed:12815058, PubMed:16782891), Involved in efficient ceramide synthesis from exogenous sphingoid bases, Converts S1P to sphingosine, which is readily metabolized to ceramide via ceramide synthase, In concert with sphingosine kinase 2 (SphK2), recycles sphingosine into ceramide through a phosphorylation/dephosphorylation cycle (By similarity), Regulates endoplasmic-to-Golgi trafficking of ceramides, resulting in the regulation of ceramide levels in the endoplasmic reticulum, preferentially long-chain ceramide species, and influences the anterograde membrane transport of both ceramide and proteins from the endoplasmic reticulum to the Golgi apparatus (PubMed:16782891), The modulation of intracellular ceramide levels in turn regulates apoptosis (By similarity), Via S1P levels, modulates resting tone, intracellular Ca(2+) and myogenic vasoconstriction in resistance arteries (PubMed:18583713), Also involved in unfolded protein response (UPR) and ER stress-induced autophagy via regulation of intracellular S1P levels (PubMed:20798685, PubMed:18583713), Involved in the regulation of epidermal homeostasis and keratinocyte differentiation (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the type 2 lipid phosphate phosphatase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSLRQRLAQLVGRLQDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSNWPLYCLFCFGTELGNELFYILFFPFWIWNLDPLVGRRLVVIWVLVMYLGQCTKDIIRWPRPASPPVVKLEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPCWCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHLALGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAGPPITVTLFGKAILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQHMEVELPYRYITYGMVGFSITFFVPYIFFFIGIS", "length": 441, "molWeight": 49108, "crc64": "86A018DDDA3A3019", "md5": "F84BC6A5FFB437B014456131C75DBC65"}}
{"primaryAccession": "Q9BXB5", "text": "This is Oxysterol-binding protein-related protein 10 protein, from Human, contains 764 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BXB5", "organism_name": "Human", "protein_name": "Oxysterol-binding protein-related protein 10", "length": 764, "firstPublicDate": "2002-02-11", "FUNCTION": "Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane, Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (PubMed:23934110) (Probable), Plays a role in negative regulation of lipid biosynthesis (PubMed:19554302), Negatively regulates APOB secretion from hepatocytes (PubMed:19554302, PubMed:22906437), Binds cholesterol and acidic phospholipids (PubMed:22906437), Also binds 25-hydroxycholesterol (PubMed:17428193), Binds phosphatidylserine (PubMed:23934110)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the OSBP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MERAVQGTDGGGGSNSSSRSSSRATSAGSSPSCSLAGRGVSSRSAAAGLGGGGSRSSPGSVAASPSGGGGRRREPALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACAKYHMEMNSKSAPSSRSRSLTLLPHGTPNSASPCSQRHLSVGAPGVVTITHHKSPAAARRAKSQYSGQLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLNLLQQSVHQAGQPSQKPGASENILGWHGSKSHSTEQLKNGTLGSLPSASANITWAILPNSAEDEQTSQPEPEPNSGSELVLSEDEKSDNEDKEETELGVMEDQRSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILTIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTTLPVYPKKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLWKAH", "length": 764, "molWeight": 83970, "crc64": "62B1DF599C7C15FC", "md5": "3C96C62368AC81720293722043B6BEE7"}}
{"primaryAccession": "Q9BXS1", "text": "This is Isopentenyl-diphosphate delta-isomerase 2 protein, from Human, contains 227 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BXS1", "organism_name": "Human", "protein_name": "Isopentenyl-diphosphate delta-isomerase 2", "length": 227, "firstPublicDate": "2002-05-15", "FUNCTION": "Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the IPP isomerase type 1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSDINLDWVDRRQLQRLEEMLIVVDENDKVIGADTKRNCHLNENIEKGLLHRAFSVVLFNTKNRILIQQRSDTKVTFPGYFTDSCSSHPLYNPAELEEKDAIGVRRAAQRRLQAELGIPGEQISPEDIVFMTIYHHKAKSDRIWGEHEICYLLLVRKNVTLNPDPSETKSILYLSQEELWELLEREARGEVKVTPWLRTIAERFLYRWWPHLDDVTPFVELHKIHRV", "length": 227, "molWeight": 26753, "crc64": "2FD79B076D94A7D0", "md5": "F3F05211C794CEEAF417BDEA6ACBB5C2"}}
{"primaryAccession": "Q9BYG8", "text": "This is Gasdermin-C protein, from Human, contains 508 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BYG8", "organism_name": "Human", "protein_name": "Gasdermin-C", "length": 508, "firstPublicDate": "2005-07-19", "FUNCTION": "Pore-forming protein that causes membrane permeabilization and pyroptosis (PubMed:27281216), Released upon cleavage and binds to membrane inner leaflet lipids, Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis (By similarity), The functional mechanisms and physiological proteases that cleave and activate this pore-forming protein are unknown (Probable)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the gasdermin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPSMLERISKNLVKEIGSKDLTPVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVEFSLNDILEPSSSVLETVVTGPFHFSDIMIQKHKADMGVNVGIEVSVSGEASVDHGCSLEFQIVTIPSPNLEDFQKRKLLDPEPSFLKECRRRGDNLYVVTEAVELINNTVLYDSSSVNILGKIALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRKQLVIKEKAILISDDDEQRTFQDEYEISEMVGYCAARSEGLLPSFHTISPTLFNASSNDMKLKPELFLTQQFLSGHLPKYEQVHILPVGRIEEPFWQNFKHLQEEVFQKIKTLAQLSKDVQDVMFYSILAMLRDRGALQDLMNMLELDSSGHLDGPGGAILKKLQQDSNHAWFNPKDPILYLLEAIMVLSDFQHDLLACSMEKRILLQQQELVRSILEPNFRYPWSIPFTLKPELLAPLQSEGLAITYGLLEECGLRMELDNPRSTWDVEAKMPLSALYGTLSLLQQLAEA", "length": 508, "molWeight": 57692, "crc64": "9CB6054AFA1ED88C", "md5": "6C05370D0B244F2BF5B6482B3E3682AD"}}
{"primaryAccession": "Q9C0E8", "text": "This is Endoplasmic reticulum junction formation protein lunapark protein, from Human, contains 428 amino acids, has 1 C4-type; plays a role in ER morphology Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [276, 301], "description": "C4-type; plays a role in ER morphology", "keyword_description": "Zinc finger", "textural_description": "C4-type; plays a role in ER morphology Zinc finger"}], "meta_data": {"primaryAccession": "Q9C0E8", "organism_name": "Human", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "length": 428, "firstPublicDate": "2006-09-05", "FUNCTION": "Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology (PubMed:30032983), Involved in the stabilization of nascent three-way ER tubular junctions within the ER network (PubMed:24223779, PubMed:25404289, PubMed:25548161, PubMed:27619977), May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network (PubMed:25404289), May be involved in limb development (By similarity), Is involved in central nervous system development (PubMed:30032983)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the lunapark family", "domain_description": {"C4-type; plays a role in ER morphology Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGGLFSRWRTKPSTVEVLESIDKEIQALEEFREKNQRLQKLWVGRLILYSSVLYLFTCLIVYLWYLPDEFTARLAMTLPFFAFPLIIWSIRTVIIFFFSKRTERNNEALDDLKSQRKKILEEVMEKETYKTAKLILERFDPDSKKAKECEPPSAGAAVTARPGQEIRQRTAAQRNLSPTPASPNQGPPPQVPVSPGPPKDSSAPGGPPERTVTPALSSNVLPRHLGSPATSVPGMGLHPPGPPLARPILPRERGALDRIVEYLVGDGPQNRYALICQQCFSHNGMALKEEFEYIAFRCAYCFFLNPARKTRPQAPRLPEFSFEKRQVVEGSSSVGPLPSGSVLSSDNQFNEESLEHDVLDDNTEQTDDKIPATEQTNQVIEKASDSEEPEEKQETENEEASVIETNSTVPGADSIPDPELSGESLTAE", "length": 428, "molWeight": 47740, "crc64": "F5BBA4186C2691BF", "md5": "FC89C91B3DCEAABF40FCD3F0F361B9E6"}}
{"primaryAccession": "Q9C4Z7", "text": "This is Cell division topological specificity factor homolog, chloroplastic protein, from Mouse-ear cress, contains 229 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C4Z7", "organism_name": "Mouse-ear cress", "protein_name": "Cell division topological specificity factor homolog, chloroplastic", "length": 229, "firstPublicDate": "2011-04-05", "FUNCTION": "Acts as a topological specificity factor during plastid division and specify plastid constriction sites (such as the Z-ring) in a MCD1-dependent manner (PubMed:29967285, PubMed:23936263), Especially involved in epidermal plastids division in a FTSZ1-dependent manner (PubMed:26500667), Required for the proper formation of FtsZ rings at the division site in nongreen plastids (e,g, etioplasts) (PubMed:23936263), May contribute to gravitropism in stems and hypocotyls, Stimulates MIND1 ATPase activity, In cooperation with MIND1, prevents FtsZ ring formation anywhere outside of the mid-plastids", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the MinE family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAMSSGTLRISATLVSPYHHHHRNRLSLPSSSSKVDFTGFISNGVNSLETQKCTPGLAISRENTRGQVKVLARNTGDYELSPSPAEQEIESFLYNAINMGFFDRLNLAWKIIFPSHASRRSSNARIAKQRLKMILFSDRCDVSDEAKRKIVNNIIHALSDFVEIESEEKVQLNVSTDGDLGTIYSVTVPVRRVKPEYQDVDEAGTITNVEYKDTRDGSVDVRFDFYVPE", "length": 229, "molWeight": 25748, "crc64": "FC307A9E3C4DE123", "md5": "721E661FC0311B5B7706374AB5F505AE"}}
{"primaryAccession": "Q9C5P4", "text": "This is Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH3 protein, from Mouse-ear cress, contains 669 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C5P4", "organism_name": "Mouse-ear cress", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH3", "length": 669, "firstPublicDate": "2003-05-09", "FUNCTION": "Histone methyltransferase, Methylates 'Lys-9' of histone H3, H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, Suvar3-9 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQGVPGFNTVPNPNHYDKSIVLDIKPLRSLKPVFPNGNQGPPFVGCPPFGPSSSEYSSFFPFGAQQPTHDTPDLNQTQNTPIPSFVPPLRSYRTPTKTNGPSSSSGTKRGVGRPKGTTSVKKKEKKTVANEPNLDVQVVKKFSSDFDSGISAAEREDGNAYLVSSVLMRFDAVRRRLSQVEFTKSATSKAAGTLMSNGVRTNMKKRVGTVPGIEVGDIFFSRIEMCLVGLHMQTMAGIDYIISKAGSDEESLATSIVSSGRYEGEAQDPESLIYSGQGGNADKNRQASDQKLERGNLALENSLRKGNGVRVVRGEEDAASKTGKIYIYDGLYSISESWVEKGKSGCNTFKYKLVRQPGQPPAFGFWKSVQKWKEGLTTRPGLILPDLTSGAESKPVSLVNDVDEDKGPAYFTYTSSLKYSETFKLTQPVIGCSCSGSCSPGNHNCSCIRKNDGDLPYLNGVILVSRRPVIYECGPTCPCHASCKNRVIQTGLKSRLEVFKTRNRGWGLRSWDSLRAGSFICEYAGEVKDNGNLRGNQEEDAYVFDTSRVFNSFKWNYEPELVDEDPSTEVPEEFNLPSPLLISAKKFGNVARFMNHSCSPNVFWQPVIREGNGESVIHIAFFAMRHIPPMAELTYDYGISPTSEARDESLLHGQRTCLCGSEQCRGSFG", "length": 669, "molWeight": 73439, "crc64": "8878E000747FD1AB", "md5": "547130CB2C34FBA72D18E0B4FD25CA86"}}
{"primaryAccession": "Q9C5S1", "text": "This is Protein-tyrosine-phosphatase MKP1 protein, from Mouse-ear cress, contains 784 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C5S1", "organism_name": "Mouse-ear cress", "protein_name": "Protein-tyrosine-phosphatase MKP1", "length": 784, "firstPublicDate": "2012-05-16", "FUNCTION": "Protein-tyrosine-phosphatase that acts as a negative regulator of MPK6 and MPK3 signaling by dephosphorylating and repressing MPK6 and MPK3, Modulates defense response by repressing salicylic acid (SA) production, camalexin biosynthesis and SNC1-mediated responses, Acts as a negative regulator of MPK6-mediated pathogen-associated molecular pattern (PAMP) responses, including MPK6 and MPK3 activation, accumulation of extracellular reactive oxygen species and inhibition of seedling growth, Involved in UV-B stress tolerance, May be involved in salt and genotoxic stress responses", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVGREDAMGNDEAPPGSKKMFWRSASWSASRTASQVPEGDEQSLNIPCAISSGPSRRCPAAPLTPRSHHNSKARACLPPLQPLAISRRSLDEWPKAGSDDVGEWPHPPTPSGNKTGERLKLDLSSTQQRVTDKSSGLAKREKIAFFDKECSKVADHIYVGGDAVAKDKSILKNNGITHILNCVGFICPEYFKSDFCYRSLWLQDSPSEDITSILYDVFDYFEDVREQSGRIFVHCCQGVSRSTSLVIAYLMWREGQSFDDAFQYVKSARGIADPNMGFACQLLQCQKRVHAFPLSPTSLLRMYKMSPHSPYDPLHLVPKLLNDPCPGSLDSRGAFIIQLPSAIYIWVGRQCETIMEKDAKAAVCQIARYEKVEAPIMVVREGDEPVYYWDAFASILPMIGGSVIKVQPGDRKVDAYNLDFEIFQKAIEGGFVPTLASSNNEHETHLPARENSWSSLKCKFASRFDKGFRYVSKTPLSRVYSDSMMIVHSSGSPSSTTSSSSTASPPFLSPDSVCSTNSGNSLKSFSQSSGRSSLRPSIPPSLTLPKFSSLSLLPSQTSPKESRGVNTFLQPSPNRKASPSLAERRGSLKGSLKLPGLADSNRGTPAFTLHPDDSNDIVFNLEGIRNGDLYPPSDCKGTSVDSDLPEKEIISLISCSKSDRHKSGGDTDSSGQPLACRWPSMEMITKLSRAYLDSESVIAIPLPSDAVGETGSRNLYIWIGKSFSLDNNCSLVDSNKAADTVENVDWVQIGESILCQMDLPKDTPIKIVRESEDQTELLALLSAL", "length": 784, "molWeight": 85964, "crc64": "DF14442F304BD1ED", "md5": "84B489CC7C9D1873047CB4BA68C470C6"}}
{"primaryAccession": "Q9C5S2", "text": "This is Serine/threonine-protein kinase/endoribonuclease IRE1a protein, from Mouse-ear cress, contains 841 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C5S2", "organism_name": "Mouse-ear cress", "protein_name": "Serine/threonine-protein kinase/endoribonuclease IRE1a", "length": 841, "firstPublicDate": "2013-05-01", "FUNCTION": "Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation, The active endoribonuclease domain splices bZIP60 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator which then induces transcription of UPR target genes, Involved in organ growth regulation, Plays a role in plant immunity and abiotic stress responses", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPPRCPFLRHLFFLLLLLSPWIMSPCGGAADDVTYPIVPSSPGRRSILQIRREPPTEPNTKLVVDRDGKVFLKQQPKETPYWSFSTGSPMHSLYQAPANNNTENATEITRPHIIVEYLNNSKAATTVDGYHNWTVQEFFRQKPLVTDDGVTLGSETTSAYLVDGRSGRLIHVYKSTGDTKITNALVKPASTEDFVNEPLLIRRTDSKLEHFSKTTGKLVWNLTVSHFRAALLCDPVFNSGYDLGPKLQTGIYMPLLCGSQIDVRGPEIVIRVLHDQPMNVKMLPSPSLNHFESENSIMPFGKARESRKLQEQHKQKYTYLFGQWSPVKLLAPLVLLGVVVSVFIKKFSSRGSDVSLKAGPSKKKKNRKSAKDTNRQSVPRGQDQFELIEGGQMLLGFNNFQSGATDGRKIGKLFLSSKEIAKGSNGTVVFEGIYEGRPVAVKRLVRSHHEVAFKEIQNLIASDQHTNIIRWYGVEYDQDFVYLSLERCTCSLDDLIKSYLEFSMTKVLENNDSTEGVAAYKIQLDSLEGVIKGNNFWKVGGHPSPLMLKLMRDIVCGIVHLHELGIVHRDLKPQNVLISKDMTLSAKLSDMGISKRMSRDMSSLGHLATGSGSSGWQAPEQLLQGRQTRAVDMFSLGCVIFYTITGCKHPFGDDLERDVNIVKNKVDLFLVEHVPEASDLISRLLNPDPDLRPSATEVLLHPMFWNSEMRLSFLRDASDRVELENREADSEILKAMESTAPVAIGGKWDEKLEPVFITNIGRYRRYKYDSIRDLLRVIRNKLNHHRELPPEIQELVGTVPEGFDEYFAVRFPKLLIEVYRVISLHCREEEVFRKYFKCDII", "length": 841, "molWeight": 95138, "crc64": "B3662AB218C31013", "md5": "87319E86D6FB012F733FD2C1B9F18A0B"}}
{"primaryAccession": "Q9C658", "text": "This is Protein decapping 5 protein, from Mouse-ear cress, contains 611 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C658", "organism_name": "Mouse-ear cress", "protein_name": "Protein decapping 5", "length": 611, "firstPublicDate": "2012-07-11", "FUNCTION": "As a component of the decapping complex, involved in the degradation of mRNAs, Promotes P-body formation, Translational repressor", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the LSM14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAADNTGSKSSSAADSYVGSLISLTSKSEIRYEGILYNINTDESSIGLQNVRSFGTEGRKKDGPQVPPSDKVYEYILFRGTDIKDLQVKASPPVQPPASTINNDPAIIQSHYPSPMPTSGSLPSTASGSLPDISSHNGQPGQHGMGFQNAMPLYQPGGNLGSWGASPQPPMYWQGFYTPPPNGLPQLHQQSLIRPPHGLPMPNSLQQPLQYPNFNTPPPPTGSSSLQGSSLPEAPSSLFPFSTSSQMLAPSSLPFPGLPPVTLSSSLQSTLQSAPSPSLASEMAPPLLSNKAPITAPPTLPQDTNLLSFSLSTTRATEASTGLPLSNKPSVVTGPISPPQTTPLTSAPVAGVSSSISQDKPKPLLVTPGQLLQSGSSAVSLSPPSTNADKDVEVVQVSSSAGLEQSVPVTSEAQPPILPLPSSARPTQKPNGHSFPNHNGYRGRGRGRGRGAGRSHQVMKFTEDFDFTAMNEKFNKDEVWGHLGKSTTLDGDEDDDSPTVDEAELPKIEAKPVYNKDDFFDSLSSNTIDRESQNSRPRFSEQRKLDTETFGEFSRFRGGRGGRGGYGRNNGYSRGGYGGRGYGGYGGRGGGGGGYGYGGRGQGRGVSNRTT", "length": 611, "molWeight": 64370, "crc64": "2BB81ABEFAB33E12", "md5": "63C95C0AF4DC523258C2946D98CBC815"}}
{"primaryAccession": "Q9C8J6", "text": "This is Phospholipase A1-Igamma3, chloroplastic protein, from Mouse-ear cress, contains 527 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C8J6", "organism_name": "Mouse-ear cress", "protein_name": "Phospholipase A1-Igamma3, chloroplastic", "length": 527, "firstPublicDate": "2010-10-05", "FUNCTION": "Acylhydrolase that catalyzes the hydrolysis of phosphatidylcholine at the sn-1 position, Moderate activity toward phosphatidylcholine (PC), monogalactosyldiacylglycerol (MGDG), digalactosyldiacylglycerol (DGDG) and triacylglycerol (TAG)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASLSLPITLKNPRFFSSSPQNIFKTQPQTLVLTTKFKTCSIICSSSCTSISSSTTQQKQSNKQTHVSDNKREEKAEEEEEEKEVSLREIWREVQGCNNWEGQLDPMNNHLRREIIRYGEFAQACYDSFDFDPHSKYCGSCKYHPSDFFLNLDLHLHKGYTITRYLYATSNINLPNFFQKSKLSSIWSQHANWMGFVAVATDEEEVSRLGRRDIVIAWRGTVTYLEWIYDLKDILCSANFGDDPSIKIELGFHDLYTKKEDSCKFSSFSAREQVLAEVKRLIEYYGTEEEGHKTSITVTGHSLGASLALVSAYDIAELNLNHVPENNYKIPITVFSFSGPRVGNLRFKERCDELGVKVLRVVNVHDKVPSVPGIFTNEKFQFQKYVEEKTSFPWSYAHVGVELALDHKKSPFLKPTKDLGCAHNLEALLHLVDGYHGKDEEAEKRFCLVTKRDIALVNKSCDFLRGEYHVPPCWRQDENKGMVKNGDGQWVLPDRPLLEPHGPEDIAHHLQQVLGKVNDDNFKPTTT", "length": 527, "molWeight": 60321, "crc64": "2161452F6CF71A92", "md5": "48B7ABB1AA589650B6884E0C67B2EBE1"}}
{"primaryAccession": "Q9C8M5", "text": "This is Serine/threonine-protein kinase WAG1 protein, from Mouse-ear cress, contains 476 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C8M5", "organism_name": "Mouse-ear cress", "protein_name": "Serine/threonine-protein kinase WAG1", "length": 476, "firstPublicDate": "2014-02-19", "FUNCTION": "Serine/threonine-protein kinase involved in the regulation of auxin signaling, Acts as a positive regulator of cellular auxin efflux and regulates organ development by enhancing PIN-mediated polar auxin transport, Phosphorylates conserved serine residues in the PIN auxin efflux carriers, Phosphorylation of PIN proteins is required and sufficient for apical-basal PIN polarity that enables directional intercellular auxin fluxes, which mediate differential growth, tissue patterning and organogenesis, Acts as suppressors of root waving", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEDDGYYLDTDLDLSFTSTATDRTFTSSSARSSLARSSLTLSFNDRLSTATTPSTTTSSAATTLHHRRYDPHWTSIRAATTLSSDGRLHLRHFKLVRHLGTGNLGRVFLCHLRDCPNPTGFALKVIDRDVLTAKKISHVETEAEILSLLDHPFLPTLYARIDASHYTCLLIDYCPNGDLHSLLRKQPNNRLPISPVRFFAAEVLVALEYLHALGIVYRDLKPENILIREDGHIMLSDFDLCFKADVVPTFRSRRFRRTSSSPRKTRRGGGCFSTEVEYEREEIVAEFAAEPVTAFSKSCVGTHEYLAPELVAGNGHGSGVDWWAFGIFLYEMLYGTTPFKGGTKEQTLRNIVSNDDVAFTLEEEGMVEAKDLIEKLLVKDPRKRLGCARGAQDIKRHEFFEGIKWPLIRNYKPPEIRGLVKKTKAHAGHVTAAVTPRRNKWLWWALSHLLRSKSLSKSSSKIQSNNNYYHYVGKKL", "length": 476, "molWeight": 53820, "crc64": "743D0B8D46DC0247", "md5": "E5DAAB8DE5C50097308F47DECE7AD261"}}
{"primaryAccession": "Q9C8N5", "text": "This is Protein SENSITIVE TO PROTON RHIZOTOXICITY 1 protein, from Mouse-ear cress, contains 499 amino acids, has 1 C2H2-type Zinc finger, has 1 C2H2-type 2; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [244, 266], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [354, 385], "description": "C2H2-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9C8N5", "organism_name": "Mouse-ear cress", "protein_name": "Protein SENSITIVE TO PROTON RHIZOTOXICITY 1", "length": 499, "firstPublicDate": "2009-07-28", "FUNCTION": "Probable transcription factor, Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+), Required for the expression of genes in response to acidic stress (e,g, ALMT1 and MATE), and Al-activated citrate exudation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 1, "C2H2-type 2; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "METEDDLCNTNWGSSSSKSREPGSSDCGNSTFAGFTSQQKWEDASILDYEMGVEPGLQESIQANVDFLQGVRAQAWDPRTMLSNLSFMEQKIHQLQDLVHLLVGRGGQLQGRQDELAAQQQQLITTDLTSIIIQLISTAGSLLPSVKHNMSTAPGPFTGQPGSAVFPYVREANNVASQSQNNNNCGAREFDLPKPVLVDEREGHVVEEHEMKDEDDVEEGENLPPGSYEILQLEKEEILAPHTHFCTICGKGFKRDANLRMHMRGHGDEYKTAAALAKPNKESVPGSEPMLIKRYSCPFLGCKRNKEHKKFQPLKTILCVKNHYKRTHCDKSFTCSRCHTKKFSVIADLKTHEKHCGKNKWLCSCGTTFSRKDKLFGHIALFQGHTPAIPLEETKPSASTSTQRGSSEGGNNNQGMVGFNLGSASNANQETTQPGMTDGRICFEESFSPMNFDTCNFGGFHEFPRLMFDDSESSFQMLIANACGFSPRNVGESVSDTSL", "length": 499, "molWeight": 55207, "crc64": "A997994F205740C5", "md5": "9717C9A0255D3F45B0B415DAB41186C8"}}
{"primaryAccession": "Q9C9X7", "text": "This is Protein indeterminate-domain 14 protein, from Mouse-ear cress, contains 419 amino acids, has 3 C2H2-type Zinc finger, has 1 CCHC-type 2; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [70, 92], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [112, 142], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [148, 175], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [175, 198], "description": "CCHC-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "CCHC-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9C9X7", "organism_name": "Mouse-ear cress", "protein_name": "Protein indeterminate-domain 14", "length": 419, "firstPublicDate": "2015-01-07", "FUNCTION": "Transcription factor regulating starch metabolism by binding directly to the promoter of QQS (PubMed:21556057), The IDD14beta isoform attenuates the transcription factor activity by competitively forming heterodimers with reduced DNA-binding capacity(PubMed:21556057), Regulates lateral organ morphogenesis and gravitropic responses (PubMed:24039602), Has a redundant role with IDD16 in directing leaf and floral organ morphogenesis (PubMed:24039602), Involved in the establishment of auxin gradients through the regulation of auxin biosynthesis and transport (PubMed:24039602)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 3, "CCHC-type 2; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIDYERSNTTKNINTHHHNPPPSSSSSDLLPDGNGTAVTQKRKRRPAGTPDPEAEVVSLSPRTLLESDRYVCEICNQGFQRDQNLQMHRRRHKVPWKLLKRETNEEVRKRVYVCPEPTCLHHNPCHALGDLVGIKKHFRRKHSNHKQWICERCSKGYAVQSDYKAHLKTCGTRGHSCDCGRVFSRVESFIEHQDTCTVRRSQPSNHRLHEQQQHTTNATQTASTAENNENGDLSIGPILPGHPLQRRQSPPSEQQPSTLLYPFVTNGSIELQLLPSRNCADETSLSLSIGTMDQKTMSEVEKKSYEKGETSLEREEARRETKRQIEIAELEFAEAKRIRQHARAELHKAHLFREEASRRISATMMQITCHNCKQHFQAPAALVPPPPQTHCTDESTSLAVSYMSSATTEGEKASDRASS", "length": 419, "molWeight": 47558, "crc64": "A9EE78F7391EA840", "md5": "3498C41CFF4BB68B45E703454DA7105A"}}
{"primaryAccession": "Q9CAC5", "text": "This is NAD(P)H-quinone oxidoreductase subunit L, chloroplastic protein, from Mouse-ear cress, contains 191 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CAC5", "organism_name": "Mouse-ear cress", "protein_name": "NAD(P)H-quinone oxidoreductase subunit L, chloroplastic", "length": 191, "firstPublicDate": "2015-02-04", "FUNCTION": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain, The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone, Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the NDH complex subunit L family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSRCGSLGLYAPNALPSLSLKPRSVKSPFCITSHTKPNDTLLHNVNKMRAKACDILGAKKTILAAQLGAVLATIDHPALAITGVNNQQELSSVVLDIGIISVWYFLVMPPIIMNWLRVRWYRRKFFEMYLQFMFVFMFFPGLLLWAPFLNFRKFPRDPNMKNPWDKPTDPDSIKNVYLKYPYATPEDYDLD", "length": 191, "molWeight": 21963, "crc64": "E813C727C7580E94", "md5": "969A3BF61DE9EA2EA7E871D79A50FF77"}}
{"primaryAccession": "Q9CAE4", "text": "This is U11/U12 small nuclear ribonucleoprotein 31 kDa protein protein, from Mouse-ear cress, contains 261 amino acids, has 1 CCHC-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [153, 169], "description": "CCHC-type", "keyword_description": "Zinc finger", "textural_description": "CCHC-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9CAE4", "organism_name": "Mouse-ear cress", "protein_name": "U11/U12 small nuclear ribonucleoprotein 31 kDa protein", "length": 261, "firstPublicDate": "2014-07-09", "FUNCTION": "RNA chaperone required for proper U12 intron splicing and for normal growth and development of plants, Mainly responsible for meristem activity, Plays a role in regulating cell division", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"CCHC-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKKRKIHHSDDEEDDTFYYRYSSVAAPPPSNPKHQPSSSAKSSAPGGGSGGLAPSKSTLYVSNLDFSLTNSDIHTLFSTFGKVARVTVLKDRHTRQSRGVAFVLYVSREDAAKAARSMDAKILNGRKLTVSIAADNGRASEFIKKRVYKDKSRCYECGDEGHLSYECPKNQLGPRERPPPPKKRGRRKEEEGEAEEISWSAAAPSLAVAEEEFEEENWASVVDNEAGERLRKREAEEEEERRMKRKEKKVSYFSDESDDED", "length": 261, "molWeight": 29367, "crc64": "4A37767C92819D22", "md5": "8C134F1B58B6248DA0CB46CCB9DFFE20"}}
{"primaryAccession": "Q9CAL8", "text": "This is Proline-rich receptor-like protein kinase PERK13 protein, from Mouse-ear cress, contains 710 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CAL8", "organism_name": "Mouse-ear cress", "protein_name": "Proline-rich receptor-like protein kinase PERK13", "length": 710, "firstPublicDate": "2010-11-02", "FUNCTION": "Regulates negatively root hairs elongation", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSDSPTSSPPAPSADSAPPPDTSSDGSAAPPPTDSAPPPSPPADSSPPPALPSLPPAVFSPPPTVSSPPPPPLDSSPPPPPDLTPPPSSPPPPDAPPPIPIVFPPPIDSPPPESTNSPPPPEVFEPPPPPADEDESPPAPPPPEQLPPPASSPQGGPKKPKKHHPGPATSPPAPSAPATSPPAPPNAPPRNSSHALPPKSTAAGGPLTSPSRGVPSSGNSVPPPANSGGGYQGKTMAGFAIAGFAVIALMAVVFLVRRKKKRNIDAYSDSQYLPPSNFSIKSDGFLYGQNPTKGYSGPGGYNSQQQSNSGNSFGSQRGGGGYTRSGSAPDSAVMGSGQTHFTYEELTDITEGFSKHNILGEGGFGCVYKGKLNDGKLVAVKQLKVGSGQGDREFKAEVEIISRVHHRHLVSLVGYCIADSERLLIYEYVPNQTLEHHLHGKGRPVLEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLAKLNDSTQTHVSTRVMGTFGYLAPEYAQSGKLTDRSDVFSFGVVLLELITGRKPVDQYQPLGEESLVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGPKRPRMVQVVRALDSEGDMGDISNGNKVGQSSAYDSGQYNNDTMKFRKMAFGFDDSSDSGMYSGDYSVQDSRKGSNGASSEFTRNETENRNFNNRRY", "length": 710, "molWeight": 75372, "crc64": "8B4420A8DD8F3AA6", "md5": "4DAC760028367BB7195871D800E66059"}}
{"primaryAccession": "Q9CQ45", "text": "This is Neudesin protein, from Mouse, contains 171 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CQ45", "organism_name": "Mouse", "protein_name": "Neudesin", "length": 171, "firstPublicDate": "2004-04-26", "FUNCTION": "Acts as a neurotrophic factor in postnatal mature neurons, enhancing neuronal survival (PubMed:15605373, PubMed:31536960), Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocytes (PubMed:16547973), Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways (PubMed:15605373, PubMed:16547973), Neurotrophic activity is enhanced by binding to heme (PubMed:18056703), Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (PubMed:23576617)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the cytochrome b5 family, MAPR subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MARPAPWWRLRLLAALVLALALVPVPSAWAGQTPRPAERGPPVRLFTEEELARYGGEEEDQPIYLAVKGVVFDVTSGKEFYGRGAPYNALAGKDSSRGVAKMSLDPADLTHDTTGLTAKELEALDDVFSKVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF", "length": 171, "molWeight": 18904, "crc64": "C90C835FE2C7B3E2", "md5": "B48C5BFA4EEEFBD9BA36C93891FC963A"}}
{"primaryAccession": "Q9CQN4", "text": "This is Sclerostin domain-containing protein 1 protein, from Mouse, contains 206 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CQN4", "organism_name": "Mouse", "protein_name": "Sclerostin domain-containing protein 1", "length": 206, "firstPublicDate": "2005-03-29", "FUNCTION": "May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction, Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity), Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the sclerostin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLPPAIHLSLIPLLCILMRNCLAFKNDATEILYSHVVKPVPAHPSSNSTLNQARNGGRHFSSTGLDRNSRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESVSPAKPAQHHRERKRASKSSKHSLS", "length": 206, "molWeight": 23174, "crc64": "70D24819EB06CBC9", "md5": "2B9C422FD275077FDA28003442178FB6"}}
{"primaryAccession": "Q9CRZ8", "text": "This is Translocator protein 2 protein, from Mouse, contains 162 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CRZ8", "organism_name": "Mouse", "protein_name": "Translocator protein 2", "length": 162, "firstPublicDate": "2007-06-26", "FUNCTION": "Cholesterol-binding protein involved in the redistribution of cholesterol from lipid droplets to the endoplasmic reticulum (PubMed:19729679, PubMed:32358067), Required to meet cholesterol demands during erythropoietic differentiation (PubMed:19729679, PubMed:32358067), May play a role in transport processes at the plasma membrane of erythrocytes, including regulating VDAC-mediated ATP export, and import of the heme precursors protoporphyrin IX and 5-aminolevulinic acid (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the TspO/BZRP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQLQGPVFVGVPLLGPILICMLIHQPSSRCEDERKLPWCPPHKVILLVWVTIYSVMGYASYLVWKELGGGFRWPLALPLGLYSFQLALSWTFLVLFLAADSPGLALLDLLLLYGLVASLVFIWQPINKLAALLLLPYLAWLTVTTAITYRLWRDSLCPTYQP", "length": 162, "molWeight": 18286, "crc64": "E18816C6B98B64E3", "md5": "13B95033B26F859BC9F20B2656953786"}}
{"primaryAccession": "Q9CWH0", "text": "This is Developmental pluripotency-associated protein 2 protein, from Mouse, contains 301 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CWH0", "organism_name": "Mouse", "protein_name": "Developmental pluripotency-associated protein 2", "length": 301, "firstPublicDate": "2006-05-30", "FUNCTION": "Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSYFGLETFNENQSEENLDEESVILTLVPFKEEEEPNTDYATQSNVSSSTLDHTPPARSLVRHAGIKHPTRTIPSTCPPPSLPPIRDVSRNTLREWCRYHNLSTDGKKVEVYLRLRRHSYSKQECYIPNTSREARMKQGPKKSKIVFRGIGPPSGCQRKKEESGVLEILTSPKESTFAAWARIAMRAAQSMSKNRCPLPSNVEAFLPQATGSRWCVVHGRQLPADKKGWVRLQFLAGQTWVPDTPQRMNFLFLLPACIIPEPGVEDNLLCPECVHSNKKILRNFKIRSRAKKNALPPNMPP", "length": 301, "molWeight": 34116, "crc64": "3DAC9C0EE94984E8", "md5": "99FDC36D65FB4E9900214ED749076560"}}
{"primaryAccession": "Q9CZ16", "text": "This is Transmembrane protein 178A protein, from Mouse, contains 297 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CZ16", "organism_name": "Mouse", "protein_name": "Transmembrane protein 178A", "length": 297, "firstPublicDate": "2007-05-15", "FUNCTION": "Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1 (PubMed:26644563)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the TMEM178 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEPRALVTALSLGLSLCSLGLLVTAIFTDHWYETDPRRHKESCERSRAGADPPDQKNRLMPLSHLPLRDSPPLGRRLLPGGPGRSDPESWRSLLGLGGLDAECGRPLFATYSGLWRKCYFLGIDRDIDTLILKGIAQRCTAIKYHFSQPIRLRNIPFNLTKTIQQDEWHLLHLRRITAGFLGMAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASVSYDLNRVPKLIYSLPHDVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAHLKSGRDSTV", "length": 297, "molWeight": 33082, "crc64": "E455E4544E48AE80", "md5": "14E9F145F292CF5ECC64739ED11B0A8A"}}
{"primaryAccession": "Q9D198", "text": "This is Pre-mRNA-splicing factor SYF2 protein, from Mouse, contains 242 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9D198", "organism_name": "Mouse", "protein_name": "Pre-mRNA-splicing factor SYF2", "length": 242, "firstPublicDate": "2006-09-19", "FUNCTION": "Involved in pre-mRNA splicing as component of the spliceosome", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SYF2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAVTEVVVPADGAEARPLAAEELAAQKREQRLRKFRELHLKRNEARKLNHQEVVEEDKRLKLPANWEAKKARLEWELQEEEKKKECAARGEDYEKVKLLEISAEDAERWERRKKKKNPDLGFSDYAAAQLRQYHRLTKQIKPDMESYERQREKHGEDFFPTSNSLLHGTHVPSSEEIDRMVLDLEKQIEKRDKYSRRRPYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTAV", "length": 242, "molWeight": 28712, "crc64": "FFCC25142541B847", "md5": "FDC4518850EA91820A2282B32E2EE8FD"}}
{"primaryAccession": "Q9D1T0", "text": "This is Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 protein, from Mouse, contains 614 amino acids, has 1 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [405, 507], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "Q9D1T0", "organism_name": "Mouse", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1", "length": 614, "firstPublicDate": "2008-04-08", "FUNCTION": "Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors, Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity), Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {"Ig-like C2-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLAGGMRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIGTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESAFHSVGNLETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCATPEFVQGKEFKDFPDVLLPNYFTCRRAHIRDRKAQQVFVDEGHTVQFVCRADGDPPPAILWLSPRKHLVSAKSNGRLTVFPDGTLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHVRSYSPDWPHQPNKTFAFISNQPGEGEANSTRATVPFPFDIKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNTKHNIEIEYVPRKSDAGISSADAPRKFNMKMI", "length": 614, "molWeight": 69101, "crc64": "41CFF40C21335681", "md5": "13B85449CD237352BF02F6B368C1FA05"}}
{"primaryAccession": "Q9D6Z6", "text": "This is Interleukin-36 beta protein, from Mouse, contains 183 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9D6Z6", "organism_name": "Mouse", "protein_name": "Interleukin-36 beta", "length": 183, "firstPublicDate": "2002-11-08", "FUNCTION": "Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response, Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP, Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes, Induces expression of a number of antimicrobial peptides including beta-defensin 4 and beta-defensin 103 as well as a number of matrix metalloproteases (By similarity), Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation, Induces the production of pro-inflammatory cytokines in bone marrow-derived dendritic cells (BMDCs), including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23, and activates p38 MAPK phosphorylation in BMDCs, Involved in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II, Induces the production of IFN-gamma, IL-4 and IL-17 by T-helper 1 (Th1) cells, cultured CD4(+) T-cells and splenocytes", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the IL-1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMAFPPQSCVHVLPPKSIQMWEPNHNTMHGSSQSPRNYRVHDSQQMVWVLTGNTLTAVPASNNVKPVILSLIACRDTEFQDVKKGNLVFLGIKNRNLCFCCVEMEGKPTLQLKEVDIMNLYKERKAQKAFLFYHGIEGSTSVFQSVLYPGWFIATSSIERQTIILTHQRGKLVNTNFYIESEK", "length": 183, "molWeight": 20878, "crc64": "A3ACE339FB96F02F", "md5": "80DE7121D7DA829DCD424B1AA4C719EF"}}
{"primaryAccession": "Q9EQ14", "text": "This is Interleukin-23 subunit alpha protein, from Mouse, contains 196 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9EQ14", "organism_name": "Mouse", "protein_name": "Interleukin-23 subunit alpha", "length": 196, "firstPublicDate": "2006-10-31", "FUNCTION": "Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity (PubMed:11114383, PubMed:11390512, PubMed:16670770), Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4 (By similarity), This process leads to activation of several pathways including p38 MAPK or NF-kappa-B and promotes the production of pro-inflammatory cytokines such as interleukin-17A/IL17A (PubMed:19900478), In turn, participates in the early and effective intracellular bacterial clearance (PubMed:16157683), Promotes the expansion and survival of T-helper 17 cells, a CD4-positive helper T-cell subset that produces IL-17, as well as other IL-17-producing cells (PubMed:16648837)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the IL-6 superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLDCRAVIMLWLLPWVTQGLAVPRSSSPDWAQCQQLSRNLCMLAWNAHAPAGHMNLLREEEDEETKNNVPRIQCEDGCDPQGLKDNSQFCLQRIRQGLAFYKHLLDSDIFKGEPALLPDSPMEQLHTSLLGLSQLLQPEDHPRETQQMPSLSSSQQWQRPLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA", "length": 196, "molWeight": 22071, "crc64": "DAF4A318A2DD3B7C", "md5": "C456392FA81C142FAB3E68FE651D8BCA"}}
{"primaryAccession": "Q9EQJ4", "text": "This is Zinc finger protein 384 protein, from Rat, contains 579 amino acids, has 8 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [229, 251], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [257, 279], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [285, 307], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [318, 340], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [346, 368], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [374, 398], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [404, 426], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [434, 456], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9EQJ4", "organism_name": "Rat", "protein_name": "Zinc finger protein 384", "length": 579, "firstPublicDate": "2003-02-28", "FUNCTION": "Transcription factor that binds the consensus DNA sequence [GC]AAAAA, Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 8}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQNITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPGLVITSPSGSLVTTASSAQTFPISTPMIVSALPPGSQALQVVPDLSKKVASTLTEEGGGGGGGGGTVAPPKPPRGRKKKRMLESGLPEMNDPYVLAPGDDDDHQKDGKTYRCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNFCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQAQAQAQASQASQQQQQQQPPPPQPPHFQSPGAAPQGGGGGDSNQNPPPQCSFDLTPYKPAEHHKDICLTVTTSTIQVEHLASS", "length": 579, "molWeight": 63139, "crc64": "FBC242E0D1050C45", "md5": "064D84142E583E1F2A7AD5C177CA2DA9"}}
{"primaryAccession": "Q9EQR5", "text": "This is Lck-interacting transmembrane adapter 1 protein, from Mouse, contains 269 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9EQR5", "organism_name": "Mouse", "protein_name": "Lck-interacting transmembrane adapter 1", "length": 269, "firstPublicDate": "2005-12-20", "FUNCTION": "Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T-cell signaling in T-cells, In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation, Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRPPVPSAPLALWVLGCFSLLLWLWALCTACHRKRAQRQQTGLQDSLVPVEMPLLRQTHLCSLSKSDTRLHELHRGPRSSIAPRPASMDLLHPRWLEMSRGSTRSQVPNSAFPPRQLPRAPPAAPATAPSTSSEATYSNVGLAAIPRASLAASPVVWAGTQLTISCARLGPGAEYACIQKHKGTEQGCQELQQKAKVIPATQMDVLYSRVCKPKRRDPRPVTDQLNLQDGRTSLPLGSDVEYEAINLRGQDMKQGPLENVYESIKEMGL", "length": 269, "molWeight": 29551, "crc64": "B37A1059EB723FBF", "md5": "3E64DABF8734EA363432729FD4F59699"}}
{"primaryAccession": "Q9ERP3", "text": "This is Tripartite motif-containing protein 54 protein, from Mouse, contains 366 amino acids, has 1 RING-type Zinc finger, has 1 B box-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [26, 82], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [121, 163], "description": "B box-type", "keyword_description": "Zinc finger", "textural_description": "B box-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9ERP3", "organism_name": "Mouse", "protein_name": "Tripartite motif-containing protein 54", "length": 366, "firstPublicDate": "2005-11-08", "FUNCTION": "May bind and stabilize microtubules during myotubes formation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"RING-type Zinc finger": 1, "B box-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNFTVGFKPLLGDAHNMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHAKAEQHLMCEEHEDEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFETLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGDHLEGSSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFSVSVEHVAEMLRTIDFQPGAAGDEEDDDMALDGEEGNAGLEEERLDVPEGSGLH", "length": 366, "molWeight": 41131, "crc64": "6CD3429162D5BEFA", "md5": "E0C72FA5C786D385B1D208D07AF83470"}}
{"primaryAccession": "Q9ESP5", "text": "This is Fez family zinc finger protein 2 protein, from Mouse, contains 455 amino acids, has 6 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [272, 294], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [300, 322], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [328, 350], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [356, 378], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [384, 406], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [412, 435], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9ESP5", "organism_name": "Mouse", "protein_name": "Fez family zinc finger protein 2", "length": 455, "firstPublicDate": "2007-07-10", "FUNCTION": "Transcription repressor, Required for the specification of corticospinal motor neurons and other subcerebral projection neurons, May play a role in layer and neuronal subtype-specific patterning of subcortical projections and axonal fasciculation, Controls the development of dendritic arborization and spines of large layer V pyramidal neurons, Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 6}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASSASLETMVPPACPRAGASPATSKTLAFSIERIMAKTSEPRAPFEPRPAALEADSSQSKKLLNLCSPLPCMIPLQPLGYEVPSKTLLSYSEFWKSSLRAGGGGGGGSGGGAPVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVINQAVGLPASGSLYYFNYLDSTAYPPSELLGGHLFPSGLLNAQAPTSLAAHPKLFLLENAKLASLAADKFPHPASYPHKERLHAPLEQVLKENSALTAERGGVKSHSKLPGGSTDSKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRKLHDSVGPTATPSAKDLARTVQS", "length": 455, "molWeight": 48931, "crc64": "506C648982A0345B", "md5": "D5A7C92A63BECC5BE655479CB3F82206"}}
{"primaryAccession": "Q9FE22", "text": "This is Transcription factor HFR1 protein, from Mouse-ear cress, contains 292 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FE22", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor HFR1", "length": 292, "firstPublicDate": "2002-05-10", "FUNCTION": "Atypical bHLH transcription factor that regulates photomorphogenesis through modulation of phytochrome (e,g, PHYA) and cryptochrome signalings (Ref,4, PubMed:11090209, PubMed:10995393, PubMed:19482971), Suppresses the transcriptional regulation activity of PIF4 by forming non-DNA-binding heterodimer", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSNNQAFMELGWRNDVGSLAVKDQGMMSERARSDEDRLINGLKWGYGYFDHDQTDNYLQIVPEIHKEVENAKEDLLVVVPDEHSETDDHHHIKDFSERSDHRFYLRNKHENPKKRRIQVLSSDDESEEFTREVPSVTRKGSKRRRRDEKMSNKMRKLQQLVPNCHKTDKVSVLDKTIEYMKNLQLQLQMMSTVGVNPYFLPATLGFGMHNHMLTAMASAHGLNPANHMMPSPLIPALNWPLPPFTNISFPHSSSQSLFLTTSSPASSPQSLHGLVPYFPSFLDFSSHAMRRL", "length": 292, "molWeight": 33615, "crc64": "BC75C5EB26E10A20", "md5": "05CCD90FA3F2DF795CAF2B47A6B55F1F"}}
{"primaryAccession": "Q9FEE2", "text": "This is Probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2 protein, from Mouse-ear cress, contains 480 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FEE2", "organism_name": "Mouse-ear cress", "protein_name": "Probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2", "length": 480, "firstPublicDate": "2013-02-06", "FUNCTION": "Probable regulatory subunit of type 2A protein phosphatase involved in the control of the dynamic organization of the cortical cytoskeleton, Plays an important role in the organization of interphase microtubule arrays in part through the regulation of nucleation geometry, Required for the reorganization of cortical arrays in response to light", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MYSGSSDGESHDTSTQRKIPPASSMLWVRNLRRYIGSGAGLGSEALMELETKRILLEIFKEKQQKSQEAGTIPSFYKKKPEEGSISQRVQKLAKYRFLKKQSDLLLNADDLAAMWVCLRENCVIDDATGAEKMNYEDFCHIASVCTEQIGPKCRRFFSPSNFMKFEKDEAGRIAILPFYLYVMRTVSLTQARIDMSELDEDSDGFLHSDEMESYIGGLIPNLAQLRDMPPAFNQMYCRIASQKFFFFCDPHRRGRACIKKILLSNCLQELMELHQESEEEVTDTEQAENWFSLTSAQRICDMFLALDKDMSGSLCKQELKEYADGTLTEIFIERVFDEHVRRGKIVAGNSREMDFDSFLDFVLALENKDTPEGLTYLFRCLDLQGRGFLTTADIHSLFRDVHQKWIEGGNYELCIEDVRDEIWDMVKPSDPLKITLGDLLGCKQGGTVASMLIDVRGFWAHDNRENLLQEEEEPPEEESQ", "length": 480, "molWeight": 55070, "crc64": "2568ABC3E898574A", "md5": "069C4F357D194C4A02343646B306A04C"}}
{"primaryAccession": "Q9FEN9", "text": "This is Chromatin remodeling protein SHL protein, from Mouse-ear cress, contains 228 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [139, 190], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9FEN9", "organism_name": "Mouse-ear cress", "protein_name": "Chromatin remodeling protein SHL", "length": 228, "firstPublicDate": "2015-12-09", "FUNCTION": "Chromatin remodeling factor that binds to methylated histone (e,g, H3K4me2/3) to prevent their acetylation (e,g, H3K9K14Ac), likely by recruiting histone deacetylase (HDAC) complexes, and thus regulate the transcription of target genes (PubMed:25281686), Required during development and for fertility, probably by modulating developmental gene expression (PubMed:11129039, PubMed:15082927, PubMed:25281686), Promotes development speed, but at fitness cost (PubMed:11129039), Involved in the chromatin-mediated repression of floral initiation and controls genes regulating flowering, Negatively regulates the expression of the floral integrator SOC1, by preventing high levels of H3 acetylation, thus maintaining an inactive chromatin conformation (PubMed:25281686)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SHL1/EBS protein family", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPKQKAPRKQLKSYKLKHINKSIQEGDAVLMRSSEPGKPSYVARVEAIETDARGSHAKVRVRWYYRPEESIGGRRQFHGAKEVFLSDHFDFQSADTIEGKCKVHSFSSYTKLDSVGNDDFFCRFEYNSTTGAFDPDRVTVFCKCEMPYNPDDLMVQCEECSEWFHPSCIGTTIEEAKKPDNFYCEECSPQQQNLHNSNSTSNNRDAKVNGKRSLEVTKSKNKHTKRPG", "length": 228, "molWeight": 26122, "crc64": "A800BC81E5B8390A", "md5": "84098CE9F52C70C8510980B90B710073"}}
{"primaryAccession": "Q9FFD9", "text": "This is Seipin-1 protein, from Mouse-ear cress, contains 368 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FFD9", "organism_name": "Mouse-ear cress", "protein_name": "Seipin-1", "length": 368, "firstPublicDate": "2015-12-09", "FUNCTION": "Involved in lipid metabolism and lipid droplet (LD) morphology, number, and size, Facilitates the formation of large-sized LDs and modulates triacylglycerol accumulation, Induces probably a reorganization of the endoplasmic reticulum into LD-forming domains", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the seipin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRILQNKTMKEQDNQLKIPEPLRADWFMVLVTIQADLIYNALVVLSSPFFLLYRSYRRAVVTVSAAEKAVKRAPAQIAGGAGRVVRRTWFGILGACHVSMVMVLALILAVVIGVGIVSLYVEKPVVVRDRLFFDYTEENPSAVFSFDKKKRSFSVPVGHSVHVSLVLWMPESEINRRIGVFQLKVELLSLKGETIARSSQPCMLRFRSKPIRLARTFVMSVPLIAGIANEAQTMRIDALKHQEKMPRTKAVRATLIPRAQTRTLPQLYEAEIVINSKPPWIKRMAYNWKWTLCVWTSMYLYVAILTALLWCFRPVLFPYTSSRTISESENLEIEVVEEEQEQVMERRRRERRNQPRRRNFATTQKSYT", "length": 368, "molWeight": 42479, "crc64": "5F303998BF779C7A", "md5": "5E50DAB9D7FA30C1DE49D8AE8392794C"}}
{"primaryAccession": "Q9FFH3", "text": "This is Zinc finger protein NUTCRACKER protein, from Mouse-ear cress, contains 466 amino acids, has 2 C2H2-type Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, has 1 CCHC-type 2; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [66, 88], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [107, 137], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [142, 165], "description": "C2H2-type 2; degenerate", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 2; degenerate Zinc finger"}, {"location": [169, 192], "description": "CCHC-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "CCHC-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9FFH3", "organism_name": "Mouse-ear cress", "protein_name": "Zinc finger protein NUTCRACKER", "length": 466, "firstPublicDate": "2008-06-10", "FUNCTION": "Transcription activator that binds to the DNA sequence 5'-CTTTTGTCC-3' (PubMed:21265895, PubMed:25929516), Regulates photoperiodic flowering by modulating sugar transport and metabolism (PubMed:21265895, PubMed:25929516), Regulates SUS1 and SUS4 (PubMed:21265895), Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:25829440), Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:25829440)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 2, "C2H2-type 2; degenerate Zinc finger": 1, "CCHC-type 2; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTSEVLQTISSGSGFAQPQSSSTLDHDESLINPPLVKKKRNLPGNPDPEAEVIALSPTTLMATNRFLCEVCGKGFQRDQNLQLHRRGHNLPWKLKQRTSKEVRKRVYVCPEKTCVHHHSSRALGDLTGIKKHFCRKHGEKKWTCEKCAKRYAVQSDWKAHSKTCGTREYRCDCGTIFSRRDSFITHRAFCDALAEETAKINAVSHLNGLAAAGAPGSVNLNYQYLMGTFIPPLQPFVPQPQTNPNHHHQHFQPPTSSSLSLWMGQDIAPPQPQPDYDWVFGNAKAASACIDNNNTHDEQITQNANASLTTTTTLSAPSLFSSDQPQNANANSNVNMSATALLQKAAEIGATSTTTAATNDPSTFLQSFPLKSTDQTTSYDSGEKFFALFGSNNNIGLMSRSHDHQEIENARNDVTVASALDELQNYPWKRRRVDGGGEVGGGGQTRDFLGVGVQTLCHPSSINGWI", "length": 466, "molWeight": 51189, "crc64": "4B8C618EA9CFE666", "md5": "1B55A20A03C6CC216534C411644DCEBA"}}
{"primaryAccession": "Q9FFK6", "text": "This is Nuclear pore complex protein NUP88 protein, from Mouse-ear cress, contains 810 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FFK6", "organism_name": "Mouse-ear cress", "protein_name": "Nuclear pore complex protein NUP88", "length": 810, "firstPublicDate": "2014-11-26", "FUNCTION": "Involved in the regulation of exportin-mediated nuclear protein export, Required for resistance mediated by multiple R proteins and for the appropriate nuclear accumulation of SNC1 and of the downstream defense signaling components EDS1 and NPR1, Not involved in salt tolerance, ethylene and auxin responses, but required for systemic acquired resistance", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKFNFNETEDAPDSRRSPTPKEPVRWVPLQSHPVFASLPSSQDEPAVSQLFPRNFMAWDGDSRVYYWDSRRYLLHRLSLRLGEPEPSSVLAAVPSKVMQPDLQVTFSVSKISINKSGSAVLLAGSDGICVMYLFGRASVIEDNVICRVVSIGSEIYTSSDSAITLLQASWHPDSDTHLGILSSDAVFRLFDLSSDTELPEQEYYLQPGEPGRSRTASSIYPADFSFGGDHLWDRFTVFILFTDGSIYILCPVVPFGSVYKWESVMEIYNDANMYGVKSSNSLAVSNSSLAIEWLEATFPDLTEQGTRGENILVVKAQPYALLDASLALQGPLYKASSGDGDEDFAVREAECKGRAVSLLYNLVSKDSILVTAWSAGQLQVDALVDEIQPVWISGNSSRLRMNSHNKIQGVAMICESNISELPVATSNLPLDHTVWLGHPPPLLRLAMVDLALPKMREGGSLVTLFADSLLPERIYSLHDGGIDSTVLHSLPFTSQASGKDEALKTPSVHTVLSTCQEESAVSPLLGFVPLSDSFGYSWIVAVLSSGECIVAEMKTWDLLLPIHVSTDKTVSSSAIEKKEQENSCIISKELLAGPKIRIAPHALPNQRSTPANSVEGRSILLDYVKLFHENYIEYAHKVHFELQHHAPNLKRIIDDQHQRLAEANEKISKVEKNQSFLEKRIDKAIERHDSLEQCLQRLRSLPGTHKKPLTRAELDFKSELDQYAGVEVDALQSSIETLRARVKKSTQKSHKGTVVAASQKKQYSKKNLIQDTQMSQLQSTLAKLSLMNSDNSKKVKIVESALKSQESSFM", "length": 810, "molWeight": 89731, "crc64": "79E20A5E4B8DF069", "md5": "22A0EC8683C26D47B8FC617A90AC1986"}}
{"primaryAccession": "Q9FG00", "text": "This is Sucrose transport protein SUC9 protein, from Mouse-ear cress, contains 491 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FG00", "organism_name": "Mouse-ear cress", "protein_name": "Sucrose transport protein SUC9", "length": 491, "firstPublicDate": "2005-12-06", "FUNCTION": "High-affinity sucrose transporter, Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system), Can also transport a wide range of glucosides, such as helicin, salicin, arbutin, maltose, fraxin, esculin, uranose, alpha-methylglucoside, alpha-phenylglucoside and beta-phenylglucoside, Plays a role in flowering time transition delay", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2,A,2,4) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSDIQAKEDAAPVDRQSSSSVVVPDEPSPLRKMISVASIAAGIQFGWALQLSLLTPYVQLLGVPHKWSSFIWLCGPISGLLVQPTVGYFSDRCKSRFGRRRPFIATGALLVALAVILIGFAADFGHTMGDKLDEAVKIRAVGFFVVGFWILDVANNTLQGPCRAFLGDLAAGDAKKTRTANAIFSFFMAVGNVLGYAAGSYTNLHKIFPFTVTKACDIYCANLKSCFIISITLLIVLTIIALWYVEDKQWSPNADSDNEKTPFFGEIFGAFKVMKRPMWMLLAVTALNWIAWFPFLLYDTDWMGREVYGGDSAGDDKMKKLYNHGIQVGSLGLMLNSIVLGVMSLVIGVISKKIGAKRLWGAVNIILAVCLAMTVLVTKKAEEHRKIAGRMALPTNAIRDGALSLFAILGIPLAITFSIPFALASIISSSSGAGQGLSLGVLNMAIVIPQMIVSFGVGPIDALFGGGNLPGFVVGAIAALISSVVALTVLP", "length": 491, "molWeight": 52578, "crc64": "AA89091CB7146352", "md5": "0771BF74014CF014AE3AAF2417DE2B5F"}}
{"primaryAccession": "Q9FH18", "text": "This is WPP domain-interacting protein 2 protein, from Mouse-ear cress, contains 509 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FH18", "organism_name": "Mouse-ear cress", "protein_name": "WPP domain-interacting protein 2", "length": 509, "firstPublicDate": "2008-09-02", "FUNCTION": "Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips (PubMed:17600715), As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDLESESSVLESVEDNNGLIGDLDKELNSPVETSPLISKGFGLRKWKRRLRRDLVKDDTSVSMENSKALKRVLSGLVDPNAKQMHLPGPEVRQDSVGSVGSVNSVVGFVMGGESYGNGLAFAAGVDSDNSEDRSSTMSHSWDKHRGKVSGGKSVISSGDSSQQRKSSVEKSNKLRGERIKIEKENSHSSMESADSRSSNFVFMQGASYSLSSREQGGRRMMDYDDENSDHDAHTSKRKDNVEEEEEETEDYSQGDCVEESQIKSNGSSDNLDPLIVAVNSFQTLQEALQKELQKFQELGKEEPITSLHDGGESSSCIHAGHEGASEASSSYRFGSEKMGEMELTSLDSEILNLVNNVEHLEIKLEEAKRILEVKETQIRELESTINVSETCNGGTEIGIEDIFQQKVEAEIEYIIFSRSVGNLKRRIKLIEEEKTLGLSKLDKAETKAENLKNQAQDLQNHCVEITEIQEVECLKKRAFKTTRCLLLQLGLLFILYYSLLPEPEIAVPT", "length": 509, "molWeight": 56514, "crc64": "28500632BE3A4EBB", "md5": "F668BC26EB02DDA5FE261C82E2F2597F"}}
{"primaryAccession": "Q9FHM5", "text": "This is AT-hook motif nuclear-localized protein 4 protein, from Mouse-ear cress, contains 419 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FHM5", "organism_name": "Mouse-ear cress", "protein_name": "AT-hook motif nuclear-localized protein 4", "length": 419, "firstPublicDate": "2015-03-04", "FUNCTION": "Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity), Acts redundantly with AHL3 to regulate the formation of tissue boundary between the xylem and procambium in the root meristem, Cell-to-cell movement of AHL4 from the procambium to the xylem is critical for its function in root vascular patterning (PubMed:23335615)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEEREGTNINNIPTSFGLKQHETPLPPPGYPPRSENPNLFPVGQSSTSSAAAAVKPSENVAPPFSLTMPVENSSSELKKKRGRPRKYNPDGSLAVTLSPMPISSSVPLTSEFGSRKRGRGRGRGRGRGRGRGQGQGSREPNNNNNDNNWLKNPQMFEFNNNTPTSGGGGPAEIVSPSFTPHVLTVNAGEDVTMKIMTFSQQGSRAICILSANGPISNVTLRQSMTSGGTLTYEGHFEILSLTGSFIPSESGGTRSRAGGMSVSLAGQDGRVFGGGLAGLFIAAGPVQVMVGSFIAGQEESQQQQQQIKKQRRERLGIPTTTQASNISFGGSAEDPKARYGLNKPVVIQPPPVSAPPVSFSHEPSTNTVHGYYANNTANHIKDLFSSLPGEDREEDEDDLEGEDDEEFGGHSESDTEVPS", "length": 419, "molWeight": 44594, "crc64": "BDB62A87D187EBF0", "md5": "1DB279D063983B48949BEA158A42ADB9"}}
{"primaryAccession": "Q9FHW2", "text": "This is SWR1 complex subunit 6 protein, from Mouse-ear cress, contains 171 amino acids, has 1 HIT-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [134, 166], "description": "HIT-type", "keyword_description": "Zinc finger", "textural_description": "HIT-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9FHW2", "organism_name": "Mouse-ear cress", "protein_name": "SWR1 complex subunit 6", "length": 171, "firstPublicDate": "2013-10-16", "FUNCTION": "Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A,F/Z leading to transcriptional regulation of selected genes (e,g, FLC) by chromatin remodeling, Coodinates SWR1-C, FRI-C (FLC transcription activator complex), histone methyltransferase and general transcription factors, Represses flowering by positively regulating FLC and MAF4, Binds to the promoter region of FLC chromatin", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ZNHIT1 family", "domain_description": {"HIT-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEEEMSNRRVSNRTRKVATKMAAALTSNDNRTQAAIARLEALENDNGAIEVIDLNDDEEASLDEDDDLGYLQKKQHKGSKRKTRQAKALEARKAPKSFLELLQEANLESLPSHVPTYLKAAVGPPSSSSRRYFCSVCGYIAGYNCCLCGMRFCSIRCQNIHKDTRCQKFVA", "length": 171, "molWeight": 19137, "crc64": "250F42A946949E41", "md5": "2241ADAE7DD20E9EFC254E362FBC6FF1"}}
{"primaryAccession": "Q9FJV0", "text": "This is Mitogen-activated protein kinase kinase 6 protein, from Mouse-ear cress, contains 356 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FJV0", "organism_name": "Mouse-ear cress", "protein_name": "Mitogen-activated protein kinase kinase 6", "length": 356, "firstPublicDate": "2006-07-11", "FUNCTION": "The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis, MKK6-MPK13 module positively regulates lateral root formation, Phosphorylates and activates MPK4, Activates MPK5 and MPK13 in vitro", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVKIKSNLKQLKLSVPAQESPISSFLTASGTFHDGDFLLNQKGLRLTSDEKQSRQSDSKELDFEITAEDLETVKVIGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQEEIRKQIVQELKINQASSQCPHVVVCYHSFYHNGAFSLVLEYMDRGSLADVIRQVKTILEPYLAVVCKQVLLGLVYLHNERHVIHRDIKPSNLLVNHKGEVKISDFGVSASLASSMGQRDTFVGTYNYMSPERISGSTYDYSSDIWSLGMSVLECAIGRFPYLESEDQQNPPSFYELLAAIVENPPPTAPSDQFSPEFCSFVSACIQKDPPARASSLDLLSHPFIKKFEDKDIDLGILVGTLEPPVNYLR", "length": 356, "molWeight": 39837, "crc64": "C95016C1DAE69CED", "md5": "AB00ADD3953F2F7FFBA262AB40C37C2B"}}
{"primaryAccession": "Q9FKW0", "text": "This is Putative E3 ubiquitin-protein ligase RING1a protein, from Mouse-ear cress, contains 522 amino acids, has 1 RING-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [136, 176], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9FKW0", "organism_name": "Mouse-ear cress", "protein_name": "Putative E3 ubiquitin-protein ligase RING1a", "length": 522, "firstPublicDate": "2010-08-10", "FUNCTION": "As part of the PRC1-like complex, repress class I KNOX gene expression, PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development, PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVKNNSFSSAEIPDVADQPRDRFNPEATQDLQEKDETKEEKEGDEEVKHDEAEEDQEVVKPNDAEEDDDGDDAEEDEEEEVEAEEDEEAEEEEEEEEEEEEEEEDSKERSPSSISGDQSEFMEIDLGEIRKDVQCPICLGIIKKTRTVMECLHRFCRECIDKSMRLGNNECPACRKHCASRRSLRDDPKFDALIAALFTNIDSYEEEELAFHEDEMARNKQIQASIAQISQRQSEALVKRRSLGKEAAVLMRSPRIASGSRRRRNSRNMEQQNASEAHEDDDNDDNNNRGRDKDSSSDERGTEVRQKKRRKRSTSRSTQHPSSSGANKNNGNCADNDTEVYRDTKGISPGLVWNPEILAWGRGGTRSNTRHGNNTSGGSSKSVRNARVNKLVEYLRSSVDGSSVELDIHVKLVSLDTKCIPDLPQPYLCCRPTLLVKQLREFVALQIHLKTEEVELLVTRRRVGEDAAIENLPAVTPASAAASKDEMLSLEDNETLSRLKIDFISSHEQHLIIAYRKKQTE", "length": 522, "molWeight": 59198, "crc64": "BFC30DE83876D712", "md5": "C6BBA961CA1B40CF8C0964CF0A782C51"}}
{"primaryAccession": "Q9FLV9", "text": "This is S-type anion channel SLAH3 protein, from Mouse-ear cress, contains 635 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FLV9", "organism_name": "Mouse-ear cress", "protein_name": "S-type anion channel SLAH3", "length": 635, "firstPublicDate": "2011-02-08", "FUNCTION": "Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis (PubMed:18305482), Binds to the highly selective inward-rectifying potassium channel KAT1 and inhibits its activity, Functions as an essential negative regulator of inward potassium channels in guard cells, Essential for the efficient stomatal closure and opening in guard cells (PubMed:27002025)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the SLAC1 S-type anion channel family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEEKPNYVIQVEEELPTLLRKATTEEMVGFDNYKENGHPFPHSISRFHPSHASTTTLNGQETSRSIDTMEAHHHNYNETTPWTHQRKPSISMPTSPNVLMISDPTTSLSSENHKNSGSTGKSVKFLSQPMTKVSSLYIESGNGDDDRRQSHDNHHHHLHRQHQSGHHQNQNQAANKLKDNRYNSFKTWSGKLERQFTRKPASVEPEAPNRNNQNLNTNEAMPVDRYYDALEGPELETLRPQEEIVLPNDKKWPFLLRYPISTFGMCLGVSSQAIMWKTLATAEPTKFLHVPLWINQGLWFISVALILTIATIYLLKIILFFEAVRREYYHPIRINFFFAPFISLLFLALGVPPSIITDLPHFLWYLLMFPFICLELKIYGQWMSGGQRRLSRVANPTNHLSVVGNFVGALLGASMGLREGPIFFYAVGMAHYLVLFVTLYQRLPTNETLPKDLHPVFFLFVAAPSVASMAWAKVTGSFDYGSKVCYFIAIFLYFSLAVRINFFRGIKFSLSWWAYTFPMTGAAIATIRYATVVKSTMTQIMCVVLCAIATLVVFALLVTTIIHAFVLRDLFPNDLAIAISNRPRPKQNSQHRWLDQLRNVSSENIENYLKFTDSDSSQSNDVEACNGKTQESDSS", "length": 635, "molWeight": 72339, "crc64": "3C3C59B25D860C35", "md5": "2013B458A019B177FE17433AD3F7AB5B"}}
{"primaryAccession": "Q9FN48", "text": "This is Calcium sensing receptor, chloroplastic protein, from Mouse-ear cress, contains 387 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FN48", "organism_name": "Mouse-ear cress", "protein_name": "Calcium sensing receptor, chloroplastic", "length": 387, "firstPublicDate": "2010-11-30", "FUNCTION": "Modulates cytoplasmic Ca(2+) concentration and is crucial for proper stomatal regulation in response to elevated levels of external Ca(2+), May function by regulating concentrations of inositol 1,4,5-trisphosphate (IP3), which in turn triggers release of Ca(2+) from internal stores, May play a role in de-etiolation", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAMAEMATKSSLSAKLTLPSSSTKKTLSLRQVSVSLPTSTSISLLSLFASPPHEAKAAVSIPKDQIVSSLTEVEKTINQVQETGSSVFDATQRVFQVVGDALKPALDTALPIAKQAGEEAMKLASPAFSEASKKAQEAMQSSGFDSEPVFNAAKTVTDVAQQTSKAIEDAKPIASSTMDTISSADPSVIVVAAGAAFLAYLLLPPVFSAISFNFRGYKGDLTPAQTLDLLCTKNYLMVDIRSEKDKEKAGIPRLPSNAKNRVISIPLEELPNKVKGIVRNSKRVEAEIAALKISYLKKINKGSNIIILDSYTDSAKIVAKTLKVLGYKNCYIVTDGFSGGRGWLQSRLGTDSYNFSFAQVLSPSRIIPAASRSFGTRSGTKFLPSSD", "length": 387, "molWeight": 41285, "crc64": "81A99499D582A107", "md5": "C4BB5CF4962D3DB7E8914B3540F313EB"}}
{"primaryAccession": "Q9FNF2", "text": "This is Starch synthase 1, chloroplastic/amyloplastic protein, from Mouse-ear cress, contains 652 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FNF2", "organism_name": "Mouse-ear cress", "protein_name": "Starch synthase 1, chloroplastic/amyloplastic", "length": 652, "firstPublicDate": "2003-03-25", "FUNCTION": "Involved in the synthesis of short glycan chains within amylopectin in leaves, Is required to generate chains up to about a degree of polymerization of 10 (DP10)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the glycosyltransferase 1 family, Bacterial/plant glycogen synthase subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASLQISGSVKFEPFVGFNRIRHFRPIASLGFPRFRRRFSIGRSLLLRRSSSFSGDSRESDEERFITDAERDGSGSVLGFQLTPPGDQQTVSTSTGEITHHEEKKEAIDQIVMADFGVPGNRAVEEGAAEVGIPSGKAEVVNNLVFVTSEAAPYSKTGGLGDVCGSLPIALAGRGHRVMVISPRYLNGTAADKNYARAKDLGIRVTVNCFGGSQEVSFYHEYRDGVDWVFVDHKSYHRPGNPYGDSKGAFGDNQFRFTLLCHAACEAPLVLPLGGFTYGEKSLFLVNDWHAGLVPILLAAKYRPYGVYKDARSILIIHNLAHQGVEPAATYTNLGLPSEWYGAVGWVFPTWARTHALDTGEAVNVLKGAIVTSDRIITVSQGYAWEITTVEGGYGLQDLLSSRKSVINGITNGINVDEWNPSTDEHIPFHYSADDVSEKIKCKMALQKELGLPIRPECPMIGFIGRLDYQKGIDLIQTAGPDLMVDDIQFVMLGSGDPKYESWMRSMEETYRDKFRGWVGFNVPISHRITAGCDILLMPSRFEPCGLNQLYAMRYGTIPVVHGTGGLRDTVENFNPYAEGGAGTGTGWVFTPLSKDSMVSALRLAAATYREYKQSWEGLMRRGMTRNYSWENAAVQYEQVFQWVFMDPPYVS", "length": 652, "molWeight": 72099, "crc64": "91E5069DCD1B2B5B", "md5": "A1DD326DAC66429F774C116AAF446119"}}
{"primaryAccession": "Q9FNZ4", "text": "This is Protein NIM1-INTERACTING 3 protein, from Mouse-ear cress, contains 112 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FNZ4", "organism_name": "Mouse-ear cress", "protein_name": "Protein NIM1-INTERACTING 3", "length": 112, "firstPublicDate": "2011-05-03", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the NPR1-interactor family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDRDRKRVKMEKEDDEEEKMEKLYTVLKNAREMRKYVNSSMEKKRQEEEERARVRRFPSFQPEDFIFMNKAEANNIEKAANESSSASNEYDGSKEKQEGSETNVCLDLNLSL", "length": 112, "molWeight": 13294, "crc64": "18048FD42FBC53C9", "md5": "D1124C2CC609EE520190B12B8F92CDA1"}}
{"primaryAccession": "Q9FQ24", "text": "This is Protein TONNEAU 1b protein, from Mouse-ear cress, contains 257 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FQ24", "organism_name": "Mouse-ear cress", "protein_name": "Protein TONNEAU 1b", "length": 257, "firstPublicDate": "2013-02-06", "FUNCTION": "Involved in the control of the dynamic organization of the cortical cytoskeleton, May play a role in the organization of microtubule arrays at the centrosome through interaction with centrin 1 (CEN1)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDDYTREMMDLKTLVTRTLEKKGVLAKIRAELRASVFEAIEEEDRVIENNEGLPPALLGSCNDRARQLHASPSGRLLSALICEYLDWAQLNHTLKVYQPECNSAKDSWKSEIRDFSINNGYELNRNEDSRPLLLDVLEGFLKFENMTQVMGGSSRRESETESSLSLDTRNPPRRSSASDSLPHQRRSVSASQASGAATSGYRKDESNWRYDTEDMPEEVMRASTALENLQLDRKTRNLTSSWRNVKDGTSEEEEGKD", "length": 257, "molWeight": 29185, "crc64": "8A80992626A20F35", "md5": "1091CF9E82418486B64CC1068E3A05DB"}}
{"primaryAccession": "Q9FQ25", "text": "This is Protein TONNEAU 1a protein, from Mouse-ear cress, contains 260 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FQ25", "organism_name": "Mouse-ear cress", "protein_name": "Protein TONNEAU 1a", "length": 260, "firstPublicDate": "2013-02-06", "FUNCTION": "Involved in the control of the dynamic organization of the cortical cytoskeleton, May play a role in the organization of microtubule arrays at the centrosome through interaction with centrin 1 (CEN1)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDDYTREMMDLKTLVTRTLEKKGVLAKIRAELRASVFEAIEEEDRVIENNEGPPPALLGSCNDRARKLHASPSGRLLSALICEYLDWAQLNHTLIVYQPESNLPKDSWKSELRDFNSNNGFELNRNGDSGPLLLDVLEGFLKFESMTQGMGSSSRRDSETESSSSLESRNPPRRSSASDSLPPQRRPVSASQASDRRAGLSTSGYRKDEFNWRQGNQDTHEEVTRASAALENLQLDRKTRNLTSSWRNVRDGTNEEEGRD", "length": 260, "molWeight": 29334, "crc64": "AECBE26FDEE6540D", "md5": "B6E672815EF1D367199EBB3A9C597BB2"}}
{"primaryAccession": "Q9FVC1", "text": "This is MADS-box protein SVP protein, from Mouse-ear cress, contains 240 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FVC1", "organism_name": "Mouse-ear cress", "protein_name": "MADS-box protein SVP", "length": 240, "firstPublicDate": "2001-12-05", "FUNCTION": "Transcription repressor that inhibit floral transition in the autonomous flowering pathway, independent of photoperiod and temperature, Acts in a dosage-dependent manner, Together with AGL24 and AP1, controls the identity of the floral meristem and regulates expression of class B, C and E genes, Promotes EFM expression to suppress flowering (PubMed:25132385)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAREKIQIRKIDNATARQVTFSKRRRGLFKKAEELSVLCDADVALIIFSSTGKLFEFCSSSMKEVLERHNLQSKNLEKLDQPSLELQLVENSDHARMSKEIADKSHRLRQMRGEELQGLDIEELQQLEKALETGLTRVIETKSDKIMSEISELQKKGMQLMDENKRLRQQGTQLTEENERLGMQICNNVHAHGGAESENAAVYEEGQSSESITNAGNSTGAPVDSESSDTSLRLGLPYGG", "length": 240, "molWeight": 26896, "crc64": "C14F3B6A259DF26E", "md5": "71022481C8F73D6B3907A4B0F732BB89"}}
{"primaryAccession": "Q9FX32", "text": "This is Sucrose synthase 6 protein, from Mouse-ear cress, contains 942 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FX32", "organism_name": "Mouse-ear cress", "protein_name": "Sucrose synthase 6", "length": 942, "firstPublicDate": "2012-09-05", "FUNCTION": "Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways, Functions in callose synthesis at the site of phloem sieve elements", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyltransferase 1 family, Plant sucrose synthase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSSSQAMLQKSDSIAEKMPDALKQSRYHMKRCFASFVGGGKKLMKREHLMNEIEKCIEDSRERSKILEGLFGYILTCTQEAAVVPPFVALAARPNPGFWEYVKVNSGDLTVDEITATDYLKLKESVFDESWSKDENALEIDFGAIDFTSPRLSLSSSIGKGADYISKFISSKLGGKSDKLEPLLNYLLRLNHHGENLMINDDLNTVAKLQKSLMLAVIVVSTYSKHTPYETFAQRLKEMGFEKGWGDTAERVKETMIILSEVLEAPDNGKLDLLFSRLPTVFNVVIFSVHGYFGQQDVLGLPDTGGQVVYILDQVRALEEELLIRINQQGLGFKPQILVVTRLIPEARGTKCDQELEAIEGTKHSHILRVPFVTNKGVLRQWVSRFDIYPYLERFTQDATSKILQRLDCKPDLIIGNYTDGNLVASLMATKLGVTQGTIAHALEKTKYEDSDAKWKELDPKYHFSCQFTADLIAMNVTDFIITSTYQEIAGSKDRPGQYESHTAFTMPGLCRVVSGIDVFDPKFNIAAPGADQSVYFPYTEKDKRFTKFHPSIQELLYNEKDNAEHMGYLADREKPIIFSMARLDTVKNITGLVEWYGKDKRLREMANLVVVAGFFDMSKSNDREEKAEIKKMHDLIEKYKLKGKFRWIAAQTDRYRNSELYRCIADTKGVFVQPALYEAFGLTVIEAMNCGLPTFATNQGGPAEIIVDGVSGFHIDPNNGDESVTKIGDFFSKCRSDGLYWDNISKGGLKRIYECYTWKIYAEKLLKMGSLYGFWRQVNEDQKKAKKRYIEMLYNLQFKQLTKKVTIPEDKPLPLRLASLRNLLPKKTTNLGAGSKQKEVTETEKTKQKSKDGQEQHDVKVGEREVREGLLAADASERVKKVLESSEEKQKLEKMKIAYGQQHSQGASPVRNLFWSVVVCLYICYILKQRFFGANSAQEY", "length": 942, "molWeight": 106876, "crc64": "0AA4A92EC48815EA", "md5": "5959B45FD56CEC609BBCA1FD86792B4A"}}
{"primaryAccession": "Q9FX53", "text": "This is Trihelix transcription factor GT-1 protein, from Mouse-ear cress, contains 406 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FX53", "organism_name": "Mouse-ear cress", "protein_name": "Trihelix transcription factor GT-1", "length": 406, "firstPublicDate": "2010-11-30", "FUNCTION": "Probable transcription factor that binds specifically to the core DNA sequence 5'-GGTTAA-3', May act as a molecular switch in response to light signals", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFISDKSRPTDFYKDDHHNSSTTSTTRDMMIDVLTTTNESVDLQSHHHHNHHNHHLHQSQPQQQILLGESSGEDHEVKAPKKRAETWVQDETRSLIMFRRGMDGLFNTSKSNKHLWEQISSKMREKGFDRSPTMCTDKWRNLLKEFKKAKHHDRGNGSAKMSYYKEIEDILRERSKKVTPPQYNKSPNTPPTSAKVDSFMQFTDKGFDDTSISFGSVEANGRPALNLERRLDHDGHPLAITTAVDAVAANGVTPWNWRETPGNGDDSHGQPFGGRVITVKFGDYTRRIGVDGSAEAIKEVIRSAFGLRTRRAFWLEDEDQIIRCLDRDMPLGNYLLRLDDGLAIRVCHYDESNQLPVHSEEKIFYTEEDYREFLARQGWSSLQVDGFRNIENMDDLQPGAVYRGVR", "length": 406, "molWeight": 46676, "crc64": "0075E3A61B1CDE16", "md5": "33D42F88ED86902336DA6C4DA56790DE"}}
{"primaryAccession": "Q9FXH7", "text": "This is Protein SHI RELATED SEQUENCE 7 protein, from Mouse-ear cress, contains 345 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FXH7", "organism_name": "Mouse-ear cress", "protein_name": "Protein SHI RELATED SEQUENCE 7", "length": 345, "firstPublicDate": "2013-12-11", "FUNCTION": "Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e,g, YUC genes), as well as genes affecting stamen development, cell expansion and timing of flowering, Synergistically with other SHI-related proteins, regulates gynoecium, stamen and leaf development in a dose-dependent manner, controlling apical-basal patterning, Promotes style and stigma formation, and influences vascular development during gynoecium development, May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM), Regulates anther dehiscence and floral development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SHI protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGLFYLGGRDHNKQDHHQEKDHNEDKSNNYLYLYKDEIYNNNKGFEIFPPQYFQQQQQQNHAAAPTNLYSFGMVPSGGNINNNRSTNRSLYFNVVSDHEPVRSSTGGFTVTRQGNMNCQDCGNQAKKDCPHMRCRTCCKSRGFDCQTHVKSTWVSAAKRRERQAQLAVLPAKRIRDANSRGGGDDDDDDKEDEKNDSCGGGSALACTRVVNASSSGLETSHLPPEISSPAVFRCMRVSSIDDEDEEYAYQTAVSIGGHVFKGILYDQGPSSDHHRYSSSLNGETSHQHHLNLMDSTPSAATTNAVTAVNTNNGSIDPSSLYTAVATPFNAFVAGGTPFFASSRC", "length": 345, "molWeight": 37928, "crc64": "B783F9408126A696", "md5": "291E8663439A0AC4EDE4A55E6846DFE7"}}
{"primaryAccession": "Q9FYS5", "text": "This is HMG-Y-related protein A protein, from Maize, contains 193 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FYS5", "organism_name": "Maize", "protein_name": "HMG-Y-related protein A", "length": 193, "firstPublicDate": "2015-11-11", "FUNCTION": "Binds A/T-rich DNA (e,g, present in the storage gamma-zein gene promoter) with a highly dynamic distribution into the nucleus (PubMed:19781672, PubMed:10864924), Probably involved in endosperm development, during cells shift from a mitotic cycle to endoreduplication leading to massive synthesis of storage proteins (zeins) and starch (PubMed:10864924)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H1/H5 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATDEATKPSPIPPYPEMILAAIEGLDDKSGSNKSAISKYIEGKYGSLPPAHASLLTAHLARMKESGELVFLKNNYFRAGAPDAPPKRGRGRPPKARDPNAPAPAPKSPSSTGRGRGRPPKAKSPLEAAVKQATAGMPKPRGRPPKKAKTDGAASPSPSPAPAPAGDGSTPGKRGRGRPPKVRPAVPSETAAA", "length": 193, "molWeight": 19825, "crc64": "1AC4FBA24F5569E4", "md5": "A3C49A80E4645E028EB2E1F63CD443D9"}}
{"primaryAccession": "Q9FZ33", "text": "This is Protein AUXIN RESPONSE 4 protein, from Mouse-ear cress, contains 473 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FZ33", "organism_name": "Mouse-ear cress", "protein_name": "Protein AUXIN RESPONSE 4", "length": 473, "firstPublicDate": "2007-09-11", "FUNCTION": "Required for the auxin influx facilitator AUX1 polar trafficking and its asymmetric localization within the plasma membrane, Not involved in the PIN proteins localization", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAIITEEEEDPKTLNPPKNKPKDSDFTKSESTMKNPKPQSQNPFPFWFYFTVVVSLATIIFISLSLFSSQNDPRSWFLSLPPALRQHYSNGRTIKVQVNSNESPIEVFVAESGSIHTETVVIVHGLGLSSFAFKEMIQSLGSKGIHSVAIDLPGNGFSDKSMVVIGGDREIGFVARVKEVYGLIQEKGVFWAFDQMIETGDLPYEEIIKLQNSKRRSFKAIELGSEETARVLGQVIDTLGLAPVHLVLHDSALGLASNWVSENWQSVRSVTLIDSSISPALPLWVLNVPGIREILLAFSFGFEKLVSFRCSKEMTLSDIDAHRILLKGRNGREAVVASLNKLNHSFDIAQWGNSDGINGIPMQVIWSSEASKEWSDEGQRVAKALPKAKFVTHSGSRWPQESKSGELADYISEFVSLLPKSIRRVAEEPIPEEVQKVLEEAKAGDDHDHHHGHGHAHAGYSDAYGLGEEWTTT", "length": 473, "molWeight": 52419, "crc64": "D09124A11565BB23", "md5": "F2A4B7411B864CAC4CFF2B0D2E109ADC"}}
{"primaryAccession": "Q9GKK3", "text": "This is Beta-casein protein, from Horse, contains 241 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9GKK3", "organism_name": "Horse", "protein_name": "Beta-casein", "length": 241, "firstPublicDate": "2005-08-16", "FUNCTION": "Important role in determination of the surface properties of the casein micelles", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the beta-casein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKILILACLVALALAREKEELNVSSETVESLSSNEPDSSSEESITHINKEKLQKFKHEGQQQREVERQDKISRFVQPQPVVYPYAEPVPYAVVPQSILPLAQPPILPFLQPEIMEVSQAKETILPKRKVMPFLKSPIVPFSERQILNPTNGENLRLPVHLIQPFMHQVPQSLLQTLMLPSQPVLSPPQSKVAPFPQPVVPYPQRDTPVQAFLLYQDPRLGPTGELDPATQPIVAVHNPVIV", "length": 241, "molWeight": 27049, "crc64": "140B6EBF3D2323C0", "md5": "C9803B68F1462F3285B9B9128752BE27"}}
{"primaryAccession": "Q9GZN4", "text": "This is Brain-specific serine protease 4 protein, from Human, contains 317 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9GZN4", "organism_name": "Human", "protein_name": "Brain-specific serine protease 4", "length": 317, "firstPublicDate": "2001-10-18", "FUNCTION": "Preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQGSGAAARS", "length": 317, "molWeight": 33732, "crc64": "E2A123BC86E79935", "md5": "D77F039083B111CD39227B1F34A31E87"}}
{"primaryAccession": "Q9GZN7", "text": "This is Protein rogdi homolog protein, from Human, contains 287 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9GZN7", "organism_name": "Human", "protein_name": "Protein rogdi homolog", "length": 287, "firstPublicDate": "2008-01-15", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the rogdi family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATVMAATAAERAVLEEEFRWLLHDEVHAVLKQLQDILKEASLRFTLPGSGTEGPAKQENFILGSCGTDQVKGVLTLQGDALSQADVNLKMPRNNQLLHFAFREDKQWKLQQIQDARNHVSQAIYLLTSRDQSYQFKTGAEVLKLMDAVMLQLTRARNRLTTPATLTLPEIAASGLTRMFAPALPSDLLVNVYINLNKLCLTVYQLHALQPNSTKNFRPAGGAVLHSPGAMFEWGSQRLEVSHVHKVECVIPWLNDALVYFTVSLQLCQQLKDKISVFSSYWSYRPF", "length": 287, "molWeight": 32254, "crc64": "E14BB4043E01A5D4", "md5": "359CE058573D9E7B82E32C772E04B5A0"}}
{"primaryAccession": "Q9GZP0", "text": "This is Platelet-derived growth factor D protein, from Human, contains 370 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9GZP0", "organism_name": "Human", "protein_name": "Platelet-derived growth factor D", "length": 370, "firstPublicDate": "2006-09-19", "FUNCTION": "Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis, Potent mitogen for cells of mesenchymal origin, Plays an important role in wound healing, Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis, Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the PDGF/VEGF growth factor family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRDESNHLTDLYRRDETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASETNWESVTSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMYLDTPRYRGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCICSSRPPR", "length": 370, "molWeight": 42848, "crc64": "D387F485E7BB7674", "md5": "10CD5CD706E0CDE017D9E56738D9EB49"}}
{"primaryAccession": "Q9GZV9", "text": "This is Fibroblast growth factor 23 protein, from Human, contains 251 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9GZV9", "organism_name": "Human", "protein_name": "Fibroblast growth factor 23", "length": 251, "firstPublicDate": "2001-04-27", "FUNCTION": "Regulator of phosphate homeostasis (PubMed:11062477), Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (PubMed:11409890), Up-regulates EGR1 expression in the presence of KL (By similarity), Acts directly on the parathyroid to decrease PTH secretion (By similarity), Regulator of vitamin-D metabolism (PubMed:15040831), Negatively regulates osteoblast differentiation and matrix mineralization (PubMed:18282132)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the heparin-binding growth factors family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLGARLRLWVCALCSVCSMSVLRAYPNASPLLGSSWGGLIHLYTATARNSYHLQIHKNGHVDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPENCRFQHQTLENGYDVYHSPQYHFLVSLGRAKRAFLPGMNPPPYSQFLSRRNEIPLIHFNTPIPRRHTRSAEDDSERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVRGGRVNTHAGGTGPEGCRPFAKFI", "length": 251, "molWeight": 27954, "crc64": "6093BD0CC50C2489", "md5": "FD174922C1009908925ABFCB61384A75"}}
{"primaryAccession": "Q9H160", "text": "This is Inhibitor of growth protein 2 protein, from Human, contains 280 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [212, 261], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9H160", "organism_name": "Human", "protein_name": "Inhibitor of growth protein 2", "length": 280, "firstPublicDate": "2005-02-15", "FUNCTION": "Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53, Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones, ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ING family", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLGQQQQQLYSSAALLTGERSRLLTCYVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKYKKEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAKMDSSQPERSSRRPRRQRTSESRDLCHMANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR", "length": 280, "molWeight": 32808, "crc64": "DC85A6ECAF7A5D81", "md5": "48DFAAEA7862A33B75FAFBC2CEFC87EF"}}
{"primaryAccession": "Q9H161", "text": "This is Homeobox protein aristaless-like 4 protein, from Human, contains 411 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H161", "organism_name": "Human", "protein_name": "Homeobox protein aristaless-like 4", "length": 411, "firstPublicDate": "2001-04-27", "FUNCTION": "Transcription factor involved in skull and limb development, Plays an essential role in craniofacial development, skin and hair follicle development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the paired homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNAETCVSYCESPAAAMDAYYSPVSQSREGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDAKSRARYGAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT", "length": 411, "molWeight": 44241, "crc64": "D41780B230C7E55C", "md5": "ECDACCD8C90EE78039A8EC15F2F2170F"}}
{"primaryAccession": "Q9H173", "text": "This is Nucleotide exchange factor SIL1 protein, from Human, contains 461 amino acids, is soluble, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H173", "organism_name": "Human", "protein_name": "Nucleotide exchange factor SIL1", "length": 461, "firstPublicDate": "2006-02-21", "FUNCTION": "Required for protein translocation and folding in the endoplasmic reticulum (ER), Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the SIL1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGRTLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR", "length": 461, "molWeight": 52085, "crc64": "C4DD7E880A610880", "md5": "C5F40E9663AF68586A80CFC2128E8B46"}}
{"primaryAccession": "Q9H255", "text": "This is Olfactory receptor 51E2 protein, from Human, contains 320 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H255", "organism_name": "Human", "protein_name": "Olfactory receptor 51E2", "length": 320, "firstPublicDate": "2001-08-29", "FUNCTION": "Olfactory receptor (PubMed:29249973, PubMed:27226631), Activated by the odorant, beta-ionone, a synthetic terpenoid (PubMed:29249973, PubMed:27226631, PubMed:19389702), The activity of this receptor is probably mediated by G-proteins leading to the elevation of intracellular Ca(2+), cAMP and activation of the protein kinases PKA and MAPK3/MAPK1 (PubMed:27226631, PubMed:29249973), Stimulation of OR51E2 by beta-ionone affects melanocyte proliferation, differentiation, and melanogenesis (PubMed:27226631), Activation of OR51E2 by beta-ionone increases proliferation and migration of primary retinal pigment epithelial (RPE) cells (PubMed:29249973), Activated also by the short-chain fatty acids (SCFA) acetate and propionate, In response to SCFA, may positively regulate renin secretion and increase blood pressure (PubMed:23401498), May also be activated by steroid hormones and regulate cell proliferation (PubMed:19389702), Activated by L-lactate in glomus cells (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSCNFTHATFVLIGIPGLEKAHFWVGFPLLSMYVVAMFGNCIVVFIVRTERSLHAPMYLFLCMLAAIDLALSTSTMPKILALFWFDSREISFEACLTQMFFIHALSAIESTILLAMAFDRYVAICHPLRHAAVLNNTVTAQIGIVAVVRGSLFFFPLPLLIKRLAFCHSNVLSHSYCVHQDVMKLAYADTLPNVVYGLTAILLVMGVDVMFISLSYFLIIRTVLQLPSKSERAKAFGTCVSHIGVVLAFYVPLIGLSVVHRFGNSLHPIVRVVMGDIYLLLPPVINPIIYGAKTKQIRTRVLAMFKISCDKDLQAVGGK", "length": 320, "molWeight": 35493, "crc64": "03582CC2AAB6E2C6", "md5": "3771D99D7704F8A8C9E0E3296073E2E1"}}
{"primaryAccession": "Q9H2W2", "text": "This is Homeobox protein MIXL1 protein, from Human, contains 232 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H2W2", "organism_name": "Human", "protein_name": "Homeobox protein MIXL1", "length": 232, "firstPublicDate": "2007-11-13", "FUNCTION": "Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation, Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages, Also involved in the morphogenesis of the heart and the gut during embryogenesis, Acts as a negative regulator of brachyury expression (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the paired homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATAESRALQFAEGAAFPAYRAPHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDPGPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVDVNCLPEPNGVGGGISDSSSQGQNFETCSPLSEDIGSKLDSWEEHIFSAFGNF", "length": 232, "molWeight": 24659, "crc64": "2E8A6A811799A8F0", "md5": "B8284BE58687E675C4AE822B403A275A"}}
{"primaryAccession": "Q9H3J6", "text": "This is Mitochondrial translation release factor in rescue protein, from Human, contains 166 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H3J6", "organism_name": "Human", "protein_name": "Mitochondrial translation release factor in rescue", "length": 166, "firstPublicDate": "2007-12-04", "FUNCTION": "Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation (PubMed:33243891), As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes, Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue (PubMed:33243891)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the prokaryotic/mitochondrial release factor family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSTVGLFHFPTPLTRICPAPWGLRLWEKLTLLSPGIAVTPVQMAGKKDYPALLSLDENELEEQFVKGHGPGGQATNKTSNCVVLKHIPSGIVVKCHQTRSVDQNRKLARKILQEKVDVFYNGENSPVHKEKREAAKKKQERKKRAKETLEKKKLLKELWESSKKVH", "length": 166, "molWeight": 18828, "crc64": "CB9B74E0CC7E920C", "md5": "C81F6896838D51E6B61D946D1E906A6E"}}
{"primaryAccession": "Q9H400", "text": "This is Lck-interacting transmembrane adapter 1 protein, from Human, contains 295 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H400", "organism_name": "Human", "protein_name": "Lck-interacting transmembrane adapter 1", "length": 295, "firstPublicDate": "2005-12-20", "FUNCTION": "Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T-cell signaling in T-cells, In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation, Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGLPVSWAPPALWVLGCCALLLSLWALCTACRRPEDAVAPRKRARRQRARLQGSATAAEASLLRRTHLCSLSKSDTRLHELHRGPRSSRALRPASMDLLRPHWLEVSRDITGPQAAPSAFPHQELPRALPAAAATAGCAGLEATYSNVGLAALPGVSLAASPVVAEYARVQKRKGTHRSPQEPQQGKTEVTPAAQVDVLYSRVCKPKRRDPGPTTDPLDPKGQGAILALAGDLAYQTLPLRALDVDSGPLENVYESIRELGDPAGRSSTCGAGTPPASSCPSLGRGWRPLPASLP", "length": 295, "molWeight": 31288, "crc64": "D85ACE978F2DC99E", "md5": "FA17BF0EDCD21AB5D287A128DA9D6365"}}
{"primaryAccession": "Q9H4F8", "text": "This is SPARC-related modular calcium-binding protein 1 protein, from Human, contains 434 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H4F8", "organism_name": "Human", "protein_name": "SPARC-related modular calcium-binding protein 1", "length": 434, "firstPublicDate": "2003-10-31", "FUNCTION": "Plays essential roles in both eye and limb development, Probable regulator of osteoblast differentiation", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEGRLV", "length": 434, "molWeight": 48163, "crc64": "2CB639212BA42478", "md5": "E7087B8520EF6784AE5E3B1907DD2FF1"}}
{"primaryAccession": "Q9H6H4", "text": "This is Receptor expression-enhancing protein 4 protein, from Human, contains 257 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H6H4", "organism_name": "Human", "protein_name": "Receptor expression-enhancing protein 4", "length": 257, "firstPublicDate": "2005-12-20", "FUNCTION": "Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis, Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DP1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVSWMICRLVVLVFGMLCPAYASYKAVKTKNIREYVRWMMYWIVFALFMAAEIVTDIFISWFPFYYEIKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDAYIVQAKERSYETVLSFGKRGLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSISDAPAPAYHDPLYLEDQVSHRRPPIGYRAGGLQDSDTEDECWSDTEAVPRAPARPREKPLIRSQSLRVVKRKPPVREGTSRSLKVRTRKKTVPSDVDS", "length": 257, "molWeight": 29395, "crc64": "EA7AB1B9EDB3DB1A", "md5": "5A67ADCBA67CC0DD5B318379943B3DFA"}}
{"primaryAccession": "Q9H867", "text": "This is Protein N-lysine methyltransferase METTL21D protein, from Human, contains 229 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H867", "organism_name": "Human", "protein_name": "Protein N-lysine methyltransferase METTL21D", "length": 229, "firstPublicDate": "2003-11-07", "FUNCTION": "Protein N-lysine methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the methyltransferase superfamily, METTL21 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MADTLESSLEDPLRSFVRVLEKRDGTVLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFPS", "length": 229, "molWeight": 25807, "crc64": "73B22FC1D14F12C7", "md5": "FF4F1D96687D870ACFACCB5E49CD2CD3"}}
{"primaryAccession": "Q9H8L6", "text": "This is Multimerin-2 protein, from Human, contains 949 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H8L6", "organism_name": "Human", "protein_name": "Multimerin-2", "length": 949, "firstPublicDate": "2003-10-03", "FUNCTION": "Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it down-regulates KDR activation by binding VEGFA", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MILSLLFSLGGPLGWGLLGAWAQASSTSLSDLQSSRTPGVWKAEAEDTGKDPVGRNWCPYPMSKLVTLLALCKTEKFLIHSQQPCPQGAPDCQKVKVMYRMAHKPVYQVKQKVLTSLAWRCCPGYTGPNCEHHDSMAIPEPADPGDSHQEPQDGPVSFKPGHLAAVINEVEVQQEQQEHLLGDLQNDVHRVADSLPGLWKALPGNLTAAVMEANQTGHEFPDRSLEQVLLPHVDTFLQVHFSPIWRSFNQSLHSLTQAIRNLSLDVEANRQAISRVQDSAVARADFQELGAKFEAKVQENTQRVGQLRQDVEDRLHAQHFTLHRSISELQADVDTKLKRLHKAQEAPGTNGSLVLATPGAGARPEPDSLQARLGQLQRNLSELHMTTARREEELQYTLEDMRATLTRHVDEIKELYSESDETFDQISKVERQVEELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHADLIKYVKDCNCQKLYLDLDVIREGQRDATRALEETQVSLDERRQLDGSSLQALQNAVDAVSLAVDAHKAEGERARAATSRLRSQVQALDDEVGALKAAAAEARHEVRQLHSAFAALLEDALRHEAVLAALFGEEVLEEMSEQTPGPLPLSYEQIRVALQDAASGLQEQALGWDELAARVTALEQASEPPRPAEHLEPSHDAGREEAATTALAGLARELQSLSNDVKNVGRCCEAEAGAGAASLNASLHGLHNALFATQRSLEQHQRLFHSLFGNFQGLMEANVSLDLGKLQTMLSRKGKKQQKDLEAPRKRDKKEAEPLVDIRVTGPVPGALGAALWEAGSPVAFYASFSEGTAALQTVKFNTTYINIGSSYFPEHGYFRAPERGVYLFAVSVEFGPGPGTGQLVFGGHHRTPVCTTGQGSGSTATVFAMAELQKGERVWFELTQGSITKRSLSGTAFGGFLMFKT", "length": 949, "molWeight": 104409, "crc64": "E4F173CF6A01FA08", "md5": "E2E9062C2F600D1A1FFD5F82847AE182"}}
{"primaryAccession": "Q9H9P8", "text": "This is L-2-hydroxyglutarate dehydrogenase, mitochondrial protein, from Human, contains 463 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H9P8", "organism_name": "Human", "protein_name": "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "length": 463, "firstPublicDate": "2006-03-21", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the L2HGDH family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVPALRYLVGACGRARGLFAGGSPGACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVGLASARALILRHPSLSIGVLEKEKDLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALLYEYCQQKGISYKQCGKLIVAVEQEEIPRLQALYEKGLQNGVPGLRLIQQEDIKKKEPYCRGLMAIDCPHTGIVDYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPIVIKNTKGEEIRCQYVVTCAGLYSDRISELSGCTPDPRIVPFRGDYLLLKPEKCYLVKGNIYPVPDSRFPFLGVHFTPRMDGSIWLGPNAVLAFKREGYRPFDFSATDVMDIIINSGLIKLASQNFSYGVTEMYKACFLGATVKYLQKFIPEITISDILRGPAGVRAQALDRDGNLVEDFVFDAGVGDIGNRILHVRNAPSPAATSSIAISGMIADEVQQRFEL", "length": 463, "molWeight": 50316, "crc64": "1B6BC0C88543B7FF", "md5": "5D6E5F9694804AB40BF069F0DD43A3FF"}}
{"primaryAccession": "Q9H9S0", "text": "This is Homeobox protein NANOG protein, from Human, contains 305 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H9S0", "organism_name": "Human", "protein_name": "Homeobox protein NANOG", "length": 305, "firstPublicDate": "2006-11-28", "FUNCTION": "Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal, Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes, Acts as a transcriptional activator or repressor, Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3', Binds to the POU5F1/OCT4 promoter (PubMed:25825768), Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression, When overexpressed, promotes cells to enter into S phase and proliferation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Nanog homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVDPACPQSLPCFEASDCKESSPMPVICGPEENYPSLQMSSAEMPHTETVSPLPSSMDLLIQDSPDSSTSPKGKQPTSAEKSVAKKEDKVPVKKQKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRWQKNNWPKNSNGVTQKASAPTYPSLYSSYHQGCLVNPTGNLPMWSNQTWNNSTWSNQTQNIQSWSNHSWNTQTWCTQSWNNQAWNSPFYNCGEESLQSCMQFQPNSPASDLEAALEAAGEGLNVIQQTTRYFSTPQTMDLFLNYSMNMQPEDV", "length": 305, "molWeight": 34620, "crc64": "AC3B2E067C591773", "md5": "40D6B007D4C2D6F89EA61EC7741A17DA"}}
{"primaryAccession": "Q9HAC7", "text": "This is Succinate--hydroxymethylglutarate CoA-transferase protein, from Human, contains 445 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HAC7", "organism_name": "Human", "protein_name": "Succinate--hydroxymethylglutarate CoA-transferase", "length": 445, "firstPublicDate": "2005-07-19", "FUNCTION": "Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA, Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the CoA-transferase III family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPSETHAMLATLARVAALRRTCLFSGRGGGRGLWTGRPQSDMNNIKPLEGVKILDLTRVLAGPFATMNLGDLGAEVIKVERPGAGDDTRTWGPPFVGTESTYYLSVNRNKKSIAVNIKDPKGVKIIKELAAVCDVFVENYVPGKLSAMGLGYEDIDEIAPHIIYCSITGYGQTGPISQRAGYDAVASAVSGLMHITGPENGDPVRPGVAMTDLATGLYAYGAIMAGLIQKYKTGKGLFIDCNLLSSQVACLSHIAANYLIGQKEAKRWGTAHGSIVPYQAFKTKDGYIVVGAGNNQQFATVCKILDLPELIDNSKYKTNHLRVHNRKELIKILSERFEEELTSKWLYLFEGSGVPYGPINNMKNVFAEPQVLHNGLVMEMEHPTVGKISVPGPAVRYSKFKMSEARPPPLLGQHTTHILKEVLRYDDRAIGELLSAGVVDQHETH", "length": 445, "molWeight": 48462, "crc64": "D1FE42D75787692A", "md5": "A319CE690F23A2B4D0B3AEC0D0F04502"}}
{"primaryAccession": "Q9HAF1", "text": "This is Chromatin modification-related protein MEAF6 protein, from Human, contains 191 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HAF1", "organism_name": "Human", "protein_name": "Chromatin modification-related protein MEAF6", "length": 191, "firstPublicDate": "2007-01-23", "FUNCTION": "Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A (PubMed:14966270), This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription (PubMed:14966270), Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4 (PubMed:16387653, PubMed:24065767), Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:18794358)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the EAF6 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAMHNKAAPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQMYGNIIRGWDRYLTNQKNSNSKNDRRNRKFKEAERLFSKSSVTSAAAVSALAGVQDQLIEKREPGSGTESDTSPDFHNQENEPSQEDPEDLDGSVQGVKPQKAASSTSSGSHHSSHKKRKNKNRHRIDLKLNKKPRADY", "length": 191, "molWeight": 21635, "crc64": "C0FBC7566BAAF1F7", "md5": "DE0C59E9CEDE2ACBBFF41DE3B18D5EFF"}}
{"primaryAccession": "Q9HAJ7", "text": "This is Histone deacetylase complex subunit SAP30L protein, from Human, contains 183 amino acids, has 1 Atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [29, 77], "description": "Atypical", "keyword_description": "Zinc finger", "textural_description": "Atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9HAJ7", "organism_name": "Human", "protein_name": "Histone deacetylase complex subunit SAP30L", "length": 183, "firstPublicDate": "2007-11-13", "FUNCTION": "Functions as transcription repressor; its activity is marginally lower than that of isoform 1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SAP30 family", "domain_description": {"Atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNGFSTEEDSREGPPAAPAAAAPGYGQSCCLIEDGERCVRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGDSPEHDTDIPEVDLFQLQVNTLRRYKRHYKLQTRPGFNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNKSRLDQKSEGGKQLE", "length": 183, "molWeight": 20877, "crc64": "EB19E448C6A1FA45", "md5": "667CC1A05CAB64DB3000C9A75AED7B33"}}
{"primaryAccession": "Q9HCC0", "text": "This is Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial protein, from Human, contains 563 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HCC0", "organism_name": "Human", "protein_name": "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "length": 563, "firstPublicDate": "2002-03-05", "FUNCTION": "Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the AccD/PCCB family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MWAVLRLALRPCARASPAGPRAYHGDSVASLGTQPDLGSALYQENYKQMKALVNQLHERVEHIKLGGGEKARALHISRGKLLPRERIDNLIDPGSPFLELSQFAGYQLYDNEEVPGGGIITGIGRVSGVECMIIANDATVKGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGAYLPRQADVFPDRDHFGRTFYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGFARIFGYPVGIVGNNGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAVACAQVPKITLIIGGSYGAGNYGMCGRAYSPRFLYIWPNARISVMGGEQAANVLATITKDQRAREGKQFSSADEAALKEPIIKKFEEEGNPYYSSARVWDDGIIDPADTRLVLGLSFSAALNAPIEKTDFGIFRM", "length": 563, "molWeight": 61333, "crc64": "8E3D401AF52DC7D2", "md5": "E1658D5269780CF79D8FECB29E533D57"}}
{"primaryAccession": "Q9HCY8", "text": "This is Protein S100-A14 protein, from Human, contains 104 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HCY8", "organism_name": "Human", "protein_name": "Protein S100-A14", "length": 104, "firstPublicDate": "2002-04-16", "FUNCTION": "Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis, Depending on the context, it can promote cell proliferation or apoptosis, Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53, Does not bind calcium", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the S-100 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGQCRSANAEDAQEFSDVERAIETLIKNFHQYSVEGGKETLTPSELRDLVTQQLPHLMPSNCGLEEKIANLGSCNDSKLEFRSFWELIGEAAKSVKLERPVRGH", "length": 104, "molWeight": 11662, "crc64": "97EF31A46B388E79", "md5": "8F307FAABC3D6DDC027A67B5B3C489A7"}}
{"primaryAccession": "Q9I7I0", "text": "This is G2/mitotic-specific cyclin-B3 protein, from Fruit fly, contains 575 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9I7I0", "organism_name": "Fruit fly", "protein_name": "G2/mitotic-specific cyclin-B3", "length": 575, "firstPublicDate": "2004-06-07", "FUNCTION": "Cyclins are positive regulatory subunits of the cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division, Probably functions redundantly with other cyclins in regulation of cell cycle, Its presence may be required to delay a deadline for completing cytokinesis that is ordinary imposed by nuclear envelope reformation, Degradation of CycB and CycB3 promote cytokinesis furrow initiation and ingression, Required with CycB for female fertility", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the cyclin family, Cyclin AB subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAPTKATTRAAITSGHHQLQQAVNPILGALGAATRKGLTRRAAATGNIDPNVENMQTRAKRKADHSPIKNDKIKRSALGNLTNNVKIMTLHPAQDEEQSGVGKKPTAQQLQALMDAKKQENLSVNVFGASKMTTRASSKVEDSVENCHKVLDKLEEALARPKPRPKAVPAAKKTVLGEVQLPAMPNPMQIPVLLPPTHNLAAPQVAAVKPVRRISNDFNKTEDSLYMSALEDVSSCDSMRLSGNFEAARRRSAKLQQKTEQQPQPLLLTLPETAPSQVVPIPPVPEEVEDFDRKNWDDPFQVSHYAMDIFNYLKVREAEFPIADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLYLAVKIVDLYLCREVINKEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERETLRVIKYDLGIPLSYRFLRRYARCAKVPMPTLTLARYILELSLMDYANISFSDSQMASAALFMALRMHGGPGQLDKQTWTSTLIYYTGYQLADFAEIVTALNAGLHRKPRATIKTIRNKYSHKIFHEVAKVPLLTNQELFQGNLDLNESNLS", "length": 575, "molWeight": 64772, "crc64": "20426777DC9C9E22", "md5": "732BB97524D1FA1FD1484D8FFE16E75A"}}
{"primaryAccession": "Q9I9E1", "text": "This is Forkhead box protein H1 protein, from Zebrafish, contains 472 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9I9E1", "organism_name": "Zebrafish", "protein_name": "Forkhead box protein H1", "length": 472, "firstPublicDate": "2001-08-14", "FUNCTION": "Transcriptional activator, Activates an activin response element (ARE), Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3', Modulator of nodal signaling required for organizer formation, Also required for the development of dorsal axial structures and left-right symmetry", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTKHWGGPGLLAPPVITVGEGAQRDHHLDCRIGYSSSKRSCHRSSNPLLELGGRLDKSTGMAQDSCYRAKATNQGPWELQDGNSSGGKKKNYQRYPKPPYSYLAMIAMVIQNSPEKKLTLSEILKEISTLFPFFKGNYKGWRDSVRHNLSSYDCFVKVLKDPGKPQGKGNFWTVEVNRIPLELLKRQNTAVSRQDETIFAQDLAPYIFQGYSQPNKSKPLPPESSLPPVPTRQSPPPSEDPYRPKLDSTFAIDSLLHSLRPASSAGEGLRERESWGVGPPPHTRSTTPPRPCNASYNGSSSASSVSPASDFSDEDWRGVTVVGKRSGDRGITSDAYSDSCPPPNKSSKRGNTPPWELPTSYAKYTPPNAVAPPSMRFNGNPFMPLGGIPFYGYGGAHVTTSHLIGHPYWPILPSGPVSIQAPPLLMDLDSMLQSVPPNKSVFDALGSNNQTVHPSPNQYALQNGPSLCKYSL", "length": 472, "molWeight": 51620, "crc64": "EC6285F1BFA970CA", "md5": "0A8863C6644340CF25CAF35E90384AFA"}}
{"primaryAccession": "Q9JHH6", "text": "This is Carboxypeptidase B2 protein, from Mouse, contains 422 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JHH6", "organism_name": "Mouse", "protein_name": "Carboxypeptidase B2", "length": 422, "firstPublicDate": "2005-04-26", "FUNCTION": "Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities, Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLHGLGILVAIILYEQHGFAFQSGQVLSALPRTSRQVQLLQNLTTTYEVVLWQPVTAEFIEKKKEVHFFVNASDVDSVKAHLNVSRIPFNVLMNNVEDLIEQQTFNDTVSPRASASYYEQYHSLNEIYSWIEVITEQHPDMLQKIYIGSSFEKYPLYVLKVSGKEQRIKNAIWIDCGIHAREWISPAFCLWFIGYVTQFHGKENLYTRLLRHVDFYIMPVMNVDGYDYTWKKNRMWRKNRSAHKNNRCVGTDLNRNFASKHWCEKGASSSSCSETYCGLYPESEPEVKAVADFLRRNIDHIKAYISMHSYSQQILFPYSYNRSKSKDHEELSLVASEAVRAIESINKNTRYTHGSGSESLYLAPGGSDDWIYDLGIKYSFTIELRDTGRYGFLLPERYIKPTCAEALAAISKIVWHVIRNT", "length": 422, "molWeight": 48871, "crc64": "99113755669D55CB", "md5": "B6FBBA6E654A4E71A03109119FB1EEFE"}}
{"primaryAccession": "Q9JHW9", "text": "This is Retinaldehyde dehydrogenase 3 protein, from Mouse, contains 512 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JHW9", "organism_name": "Mouse", "protein_name": "Retinaldehyde dehydrogenase 3", "length": 512, "firstPublicDate": "2004-09-27", "FUNCTION": "Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively (PubMed:11013254, PubMed:11044606, PubMed:14623956, PubMed:15911617), High specificity for all-trans-retinal as substrate, can also accept acetaldehyde as substrate in vitro but with lower affinity (By similarity), Required for the biosynthesis of normal levels of retinoate in the embryonic ocular and nasal regions; a critical lipid in the embryonic development of the eye and the nasal region (PubMed:14623956)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the aldehyde dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATTNGAVENGQPDGKPPALPRPIRNLEVKFTKIFINNDWHESKSGRKFATYNPSTLEKICEVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLVERDRAILATLETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVREAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRPVGDPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDRGLFIKPTVFSDVTDNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLAAALESGTVWINCYNAFYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLEEKNP", "length": 512, "molWeight": 56157, "crc64": "5BBC6DEE41E58CFE", "md5": "10B00626B9C7A84D870FBD3CB9B24B90"}}
{"primaryAccession": "Q9JIE6", "text": "This is Thymic stromal lymphopoietin protein, from Mouse, contains 140 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JIE6", "organism_name": "Mouse", "protein_name": "Thymic stromal lymphopoietin", "length": 140, "firstPublicDate": "2007-09-11", "FUNCTION": "Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells, Can induce allergic inflammation by directly activating mast cells (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVLLRSLFILQVLVRMGLTYNFSNCNFTSITKIYCNIIFHDLTGDLKGAKFEQIEDCESKPACLLKIEYYTLNPIPGCPSLPDKTFARRTREALNDHCPGYPETERNDGTQEMAQEVQNICLNQTSQILRLWYSFMQSPE", "length": 140, "molWeight": 16152, "crc64": "5B6D3196E73BAA8B", "md5": "B2159AAA2B8219797560C983EE83C958"}}
{"primaryAccession": "Q9JJK1", "text": "This is Neuronal membrane glycoprotein M6-b protein, from Rat, contains 265 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JJK1", "organism_name": "Rat", "protein_name": "Neuronal membrane glycoprotein M6-b", "length": 265, "firstPublicDate": "2012-06-13", "FUNCTION": "May be involved in neural development, Involved in regulation of osteoblast function and bone formation, Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton, May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the myelin proteolipid protein family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKPAMETAAEENTEQSQERKGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNTSDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQSNGTSGVEQICVDVRQYGIIPWNAFPGKICGSALENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCPKF", "length": 265, "molWeight": 28973, "crc64": "81BA7690D70C1333", "md5": "AD9A94628D6C8FE66EA840B91F7F24D3"}}
{"primaryAccession": "Q9JJW5", "text": "This is Myozenin-2 protein, from Mouse, contains 264 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JJW5", "organism_name": "Mouse", "protein_name": "Myozenin-2", "length": 264, "firstPublicDate": "2005-11-22", "FUNCTION": "Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere, Plays an important role in the modulation of calcineurin signaling, May play a role in myofibrillogenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the myozenin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLSHSAMVKQRKQQASAITKEIHGHDVDGMDLGKKVSIPRDIMIEELSHFSNRGARLFKMRQRRSDKYTFENFQYESRAQINHNIAMQNGRVDGSNLEGGSQQGPSTPPNTPDPRSPPNPENIAPGYSGPLKEIPPERFNTTAVPKYYRSPWEQAIGSDPELLEALYPKLFKPEGKAELRDYRSFNRVATPFGGFEKASKMVKFKVPDFELLLLTDPRFLAFANPLSGRRCFNRAPKGWVSENIPVVITTEPTEDATVPESDDL", "length": 264, "molWeight": 29762, "crc64": "2DCDC6A30B0704FD", "md5": "D1C6ED21ADC603722CACBBEF3E76BD90"}}
{"primaryAccession": "Q9JJZ5", "text": "This is Epidermal growth factor-like protein 6 protein, from Mouse, contains 550 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JJZ5", "organism_name": "Mouse", "protein_name": "Epidermal growth factor-like protein 6", "length": 550, "firstPublicDate": "2007-07-24", "FUNCTION": "May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis, Promotes matrix assembly", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the nephronectin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQPPWGLALPLLLPWVTGGVGTSPWDYGLSALAHQPGVCQYGTKMACCYGWKRNNKGVCEAMCEPRCKFGECVGPNKCRCFPGYTGKTCTQDVNECGVKPRPCQHRCVNTHGSYKCFCLSGHMLLPDATCSNSRTCARLNCQYGCEDTEEGPRCVCPSSGLRLGPNGRVCLDIDECASSKAVCPSNRRCVNTFGSYYCKCHIGFELKYIGRRYDCVDINECALNTHPCSPHANCLNTRGSFKCKCKQGYRGNGLQCSVIPEHSVKEILTAPGTIKDRIKKLLAHKRTMKKKVKLKMVTPRPASTRVPKVNLPYSSEEGVSRGRNYDGEQKKKEEGKRERLEEEKGEKTLRNEVEQERTLRGDVFSPKVNEAEDLDLVYVQRKELNSKLKHKDLNISVDCSFDLGVCDWKQDREDDFDWHPADRDNDVGYYMAVPALAGHKKNIGRLKLLLPNLTPQSNFCLLFDYRLAGDKVGKLRVFVKNSNNALAWEETKNEDGRWRTGKIQLYQGIDTTKSVIFEAERGKGKTGEIAVDGVLLVSGLCPDDFLSVEG", "length": 550, "molWeight": 61520, "crc64": "DEF936325C9F31B3", "md5": "7E25AB64542C6D614F21E851476855F1"}}
{"primaryAccession": "Q9JKA9", "text": "This is Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 protein, from Rat, contains 863 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JKA9", "organism_name": "Rat", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "length": 863, "firstPublicDate": "2003-02-28", "FUNCTION": "Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions, Contributes to the native pacemaker currents in heart (If) and in neurons (Ih), Can also transport ammonium in the distal nephron, Produces a large instantaneous current", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the potassium channel HCN family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDARGGGGRPGDSPGTTPAPGPPPPPPPPAPLQLQPPPAPPPNPTTPSHPESADEPGPRSRLCSRDSSCTPGAAKGGANGECGRGEPQCSPEGPARGPKVSFSCRGAASGPAAAEEAGSEEAGPAGEPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGFFPPPPPRQVRSAIATLQQAVAMSFCPQVARPLVGPLALGSPRLVRRAPPGPLPPAASPGPPAASPPAAPSSPRAPRTSPYGVPGSPATRVGPALPARRLSRASRPLSASQPSLPHGAPAPSPAASARPASSSTPRLGPAPTTRTAAPSPDRRDSASPGAASGLDPLDSARSRLSSNL", "length": 863, "molWeight": 94920, "crc64": "4EF55435C2384A26", "md5": "70E4A7F407DB0BAA9BBF523765B83704"}}
{"primaryAccession": "Q9JKN1", "text": "This is Zinc transporter 7 protein, from Mouse, contains 378 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JKN1", "organism_name": "Mouse", "protein_name": "Zinc transporter 7", "length": 378, "firstPublicDate": "2008-01-15", "FUNCTION": "Zinc ion transporter mediating zinc entry from the cytosol into the lumen of organelles along the secretory pathway (PubMed:12446736, PubMed:17954933), By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases (By similarity)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the cation diffusion facilitator (CDF) transporter (TC 2,A,4) family, SLC30A subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLVGIFVFNHGGHGHSHGSGHGHSHSLFNGALDHSHGHEDHCHSHEAKHGAAHSHDHDHAHGHGHLHSHDGPSFKATAGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPSLENTLPQCYQRVQQLQGVYNLQEQHFWTLCSDVYVGTLKLVVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM", "length": 378, "molWeight": 41790, "crc64": "B98AC19C9A045006", "md5": "067EDC46AA199C90BEE8AB6CC16BE717"}}
{"primaryAccession": "Q9JL61", "text": "This is DNA-binding protein Rfx5 protein, from Mouse, contains 658 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JL61", "organism_name": "Mouse", "protein_name": "DNA-binding protein Rfx5", "length": 658, "firstPublicDate": "2012-10-03", "FUNCTION": "Activates transcription from class II MHC promoters, Recognizes X-boxes, Mediates cooperative binding between RFX and NF-Y, RFX binds the X1 box of MHC-II promoters", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RFX family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAEDKPDAKSPKTGARPQGGADAGEPTTLLQRLRGTISKAVQNKVEGILQEVQKFSDNDKLYLYLQLPSGPSVGEKSSEPSLLSNEEYMYAYRWIRNHLEEHMDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDLKGSESPEMGPEVSPAPRDELVEAACALTCDWAERILKRSFSSIVQVARYLLQQHLISARSAHAHVLKAGGLAEEDERAPRERSLCKSKNVVESLEGGGPKKPERPAQPPKEQEARAGTDLPGRAERKKSVIDSSVPAASKPQVNALVARLPVLLPRAPRSLITPISGTLKVATLPLPTRVGGPQTAVPIINMILPPVPTLSGAGPGPGPGLGPRFGPGPGLGPGPGPGLGAGLGPGLGPGLGAGPGPGLGAGLGAGLGLGPGRVPPRAPILPRGAENREVGISSDPRPHDKGIKRTAEVPLSEASGQDPPVKEMKHETQDTTVSEAKRKRGRPRKKPGGSGERNATPEKSAAIVNSPRSPRLLWETWGSKRENNFIGRPEGPGPGGEAERETVLVQGQQDGAVSKGERSLSSQEAKEAEDKIPPVTSKVSVIKGRIQKEALQLVKGEADAATQGNKGLKGRVLQSSLTPEHKDPKATPP", "length": 658, "molWeight": 69735, "crc64": "E1807134D8FC4A19", "md5": "1C7D129F502D46648FE0AC5E0840F90B"}}
{"primaryAccession": "Q9JM73", "text": "This is Serum response factor protein, from Mouse, contains 504 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JM73", "organism_name": "Mouse", "protein_name": "Serum response factor", "length": 504, "firstPublicDate": "2006-07-11", "FUNCTION": "SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) (PubMed:24732378), Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration (PubMed:12732141, PubMed:19350017, PubMed:24732378), The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics (PubMed:24732378), Required for cardiac differentiation and maturation (PubMed:15169892)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLPSQAGAAAALGRGSALGGNLNRTPTGRPGGGGGTRGANGGRVPGNGAGLGQSRLEREAAAAAAPTAGALYSGSEGDSESGEEEELGAERRGLKRSLSEMELGVVVGGPEAAAAAAGGYGPVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDPTTDQRMSATGFEEPDLTYQVSESDSSGETKDTLKPAFTVTNLPGTTSTIQTAPSTSTTMQVSSGPSFPITNYLAPVSASVSPSAVSSANGTVLKSTGSGPVSSGGLMQLPTSFTLMPGGAVAQQVPVQAIHVHQAPQQASPSRDSSTDLTQTSSSGTVTLPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLADGSLTVLNAFSQAPSTMQVSHSQVQEPGGVPQVFLTAPSGTVQIPVSAVQLHQMAVIGQQAGSSSNLTELQVVNLDATHSTKSE", "length": 504, "molWeight": 51247, "crc64": "26353F18A2B46F6B", "md5": "264A4D2B4E670AFB330F7CD21C9D79A9"}}
{"primaryAccession": "Q9JM80", "text": "This is Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 protein, from Rat, contains 424 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JM80", "organism_name": "Rat", "protein_name": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "length": 424, "firstPublicDate": "2005-12-20", "FUNCTION": "Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells, Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition, Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins, May be involved in cell adhesion signaling", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGPAGSALSSGQMQMQMVLWGSLAAVAMFFLITFLILLCSSCDRDKKPRQHSGDHESLMNVPSDKEMFSHSATSLTTDALASSEQNGVLTNGDILSEDSTMTCMQHYEEVQTSASDLLDSQDSTGKAKCHQSRELPRIPPENAVDAMLTARAADGDSGPGVEGPYEVLKDSSSQENMVEDCLYETVKEIKEVADKSQGGKSKSTSALKELQGAHAEGKADFAEYASVDRNKKCRHSTNAESILGTSSDLDEETPPPVPVKLLDENANLPEKGEHGAEEQAPEAPSGHSKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQSAHKPGPESTCQCPQGPPQRSSSSCNDLYATVKDFEKTPNSISMLPPARRPGEEPEPDYEAIQTLNREDDKVPLGTNGHLVPKENDYESIGDLQQGRDVTRL", "length": 424, "molWeight": 45915, "crc64": "49ED52D44B3FB154", "md5": "6007CF2A35B2B6A489F9542B212772D6"}}
{"primaryAccession": "Q9LD83", "text": "This is Guard cell S-type anion channel SLAC1 protein, from Mouse-ear cress, contains 556 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LD83", "organism_name": "Mouse-ear cress", "protein_name": "Guard cell S-type anion channel SLAC1", "length": 556, "firstPublicDate": "2011-02-08", "FUNCTION": "Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis, Cl(-) efflux through SLAC1 causes membrane depolarization, which activates outward-rectifying K1 channels, leading to KCl and water efflux to reduce turgor further and cause stomatal closure, that reduces water loss and promotes leaf turgor, Essential for stomatal closure in response to CO(2), abscisic acid (ABA), ozone O(3), light/dark transitions, humidity change, calcium ions, hydrogen peroxide H(2)O(2), reactive oxygen species (ROS), and nitric oxide, Binds to the highly selective inward-rectifying potassium channels KAT1 and AKT2, and inhibits their activities, Functions as an essential negative regulator of inward potassium channels in guard cells, Essential for the efficient stomatal closure and opening in guard cells (PubMed:27002025), Involved in the local and/or systemic stomatal responses (e,g, stomatal closure) to light stress (PubMed:29463779)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the SLAC1 S-type anion channel family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MERKQSNAHSTFADINEVEDEAEQELQQQENNNNKRFSGNRGPNRGKQRPFRGFSRQVSLETGFSVLNRESRERDDKKSLPRSGRSFGGFESGGIINGGDGRKTDFSMFRTKSTLSKQKSLLPSIIRERDIENSLRTEDGETKDDSINENVSAGRYFAALRGPELDEVKDNEDILLPKEEQWPFLLRFPIGCFGICLGLSSQAVLWLALAKSPATNFLHITPLINLVVWLFSLVVLVSVSFTYILKCIFYFEAVKREYFHPVRVNFFFAPWVVCMFLAISVPPMFSPNRKYLHPAIWCVFMGPYFFLELKIYGQWLSGGKRRLCKVANPSSHLSVVGNFVGAILASKVGWDEVAKFLWAVGFAHYLVVFVTLYQRLPTSEALPKELHPVYSMFIAAPSAASIAWNTIYGQFDGCSRTCFFIALFLYISLVARINFFTGFKFSVAWWSYTFPMTTASVATIKYAEAVPGYPSRALALTLSFISTAMVCVLFVSTLLHAFVWQTLFPNDLAIAITKRKLTREKKPFKRAYDLKRWTKQALAKKISAEKDFEAEEESHH", "length": 556, "molWeight": 63235, "crc64": "E2E310F026EE0C01", "md5": "9179CFBD2A61389569F442237CD9022B"}}
{"primaryAccession": "Q9LES2", "text": "This is UBP1-associated protein 2A protein, from Mouse-ear cress, contains 478 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LES2", "organism_name": "Mouse-ear cress", "protein_name": "UBP1-associated protein 2A", "length": 478, "firstPublicDate": "2014-02-19", "FUNCTION": "Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as component of a complex regulating the turnover of mRNAs in the nucleus, Binds with high affinity to RNA molecules that contain U-rich sequences in 3'-UTRs, May function in complex with UBP1 and contribute to the stabilization of mRNAs in the nucleus, However, unlike UBP1, UBA2A does not stimulate pre-mRNA splicing", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTKKRKLEGEESNEAEEPSQKLKQTPEEEQQLVIKNQDNQGDVEEVEYEEVEEEQEEEVEDDDDEDDGDENEDQTDGNRIEAAATSGSGNQEDDDDEPIQDLLEPFSKEQVLSLLKEAAEKHVDVANRIREVADEDPVHRKIFVHGLGWDTKTETLIEAFKQYGEIEDCKAVFDKISGKSKGYGFILYKSRSGARNALKQPQKKIGSRMTACQLASKGPVFGGAPIAAAAVSAPAQHSNSEHTQKKIYVSNVGAELDPQKLLMFFSKFGEIEEGPLGLDKYTGRPKGFCLFVYKSSESAKRALEEPHKTFEGHILHCQKAIDGPKPGKQQQHHHNPHAYNNPRYQRNDNNGYGPPGGHGHLMAGNPAGMGGPTAQVINPAIGQALTALLASQGAGLAFNPAIGQALLGSLGTAAGVNPGNGVGMPTGYGTQAMAPGTMPGYGTQPGLQGGYQTPQPGQGGTSRGQHGVGPYGTPYMGH", "length": 478, "molWeight": 51439, "crc64": "0CD3653669BE2DA4", "md5": "80C18AA955BE4E1EECCF74616C274B62"}}
{"primaryAccession": "Q9LFU9", "text": "This is Glucosamine 6-phosphate N-acetyltransferase protein, from Mouse-ear cress, contains 149 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LFU9", "organism_name": "Mouse-ear cress", "protein_name": "Glucosamine 6-phosphate N-acetyltransferase", "length": 149, "firstPublicDate": "2013-02-06", "FUNCTION": "Acetyltransferase involved in UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis, UDP-GlcNAc is an essential metabolite that serves as an initial sugar donor for N-glycan synthesis and thus plays an important role in protein and lipid glycosylation", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the acetyltransferase family, GNA1 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAETFKIRKLEISDKRKGFIELLGQLTVTGSVTDEEFDRRFEEIRSYGDDHVICVIEEETSGKIAATGSVMIEKKFLRNCGKAGHIEDVVVDSRFRGKQLGKKVVEFLMDHCKSMGCYKVILDCSVENKVFYEKCGMSNKSIQMSKYFD", "length": 149, "molWeight": 17028, "crc64": "209AF6CB83DCC857", "md5": "7953A305CE5C2F19B7D07749B17A732A"}}
{"primaryAccession": "Q9LG05", "text": "This is Probable WRKY transcription factor 10 protein, from Mouse-ear cress, contains 485 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LG05", "organism_name": "Mouse-ear cress", "protein_name": "Probable WRKY transcription factor 10", "length": 485, "firstPublicDate": "2003-04-11", "FUNCTION": "Transcription factor, Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity), Modulates seed size by negatively regulating the cellularization of syncytial endosperm (PubMed:16293693)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WRKY group I family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSDFDENFIEMTSYWAPPSSPSPRTILAMLEQTDNGLNPISEIFPQESLPRDHTDQSGQRSGLRERLAARVGFNLPTLNTEENMSPLDAFFRSSNVPNSPVVAISPGFSPSALLHTPNMVSDSSQIIPPSSATNYGPLEMVETSGEDNAAMMMFNNDLPYQPYNVDLPSLEVFDDIATEESFYIPSYEPHVDPIGTPLVTSFESELVDDAHTDIISIEDSESEDGNKDDDDEDFQYEDEDEDQYDQDQDVDEDEEEEKDEDNVALDDPQPPPPKRRRYEVSNMIGATRTSKTQRIILQMESDEDNPNDGYRWRKYGQKVVKGNPNPRSYFKCTNIECRVKKHVERGADNIKLVVTTYDGIHNHPSPPARRSNSSSRNRSAGATIPQNQNDRTSRLGRAPPTPTPPTPPPSSYTPEEMRPFSSLATEIDLTEVYMTGISMLPNIPVYENSGFMYQNDEPTMNAMPDGSDVYDGIMERLYFKFGVDM", "length": 485, "molWeight": 54552, "crc64": "3D96CE29CC9BFAC0", "md5": "5B1D5AAC18BC286B3A1922BD8F3A8C77"}}
{"primaryAccession": "Q9LIB2", "text": "This is Alpha-glucan phosphorylase 1 protein, from Mouse-ear cress, contains 962 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LIB2", "organism_name": "Mouse-ear cress", "protein_name": "Alpha-glucan phosphorylase 1", "length": 962, "firstPublicDate": "2013-01-09", "FUNCTION": "Phosphorylase is an important allosteric enzyme in carbohydrate metabolism, Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates, However, all known phosphorylases share catalytic and structural properties (By similarity), May be not required for the degradation of starch, but the phosphorolysis of starch may play an important role in water stress tolerance", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the glycogen phosphorylase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDTMRISGVSTGAEVLIQCNSLSSLVSRRCDDGKWRTRMFPARNRDLRPSPTRRSFLSVKSISSEPKAKVTDAVLDSEQEVFISSMNPFAPDAASVASSIKYHAEFTPLFSPEKFELPKAFFATAQSVRDALIMNWNATYEYYNRVNVKQAYYLSMEFLQGRALSNAVGNLGLNSAYGDALKRLGFDLESVASQEPDPALGNGGLGRLASCFLDSMATLNYPAWGYGLRYKYGLFKQRITKDGQEEAAEDWLELSNPWEIVRNDVSYPIKFYGKVVFGSDGKKRWIGGEDIVAVAYDVPIPGYKTKTTINLRLWSTKAPSEDFDLSSYNSGKHTEAAEALFNAEKICFVLYPGDESTEGKALRLKQQYTLCSASLQDIVARFETRSGGNVNWEEFPEKVAVQMNDTHPTLCIPELMRILMDLKGLSWEDAWKITQRTVAYTNHTVLPEALEKWSLELMEKLLPRHVEIIEKIDEELVRTIVSEYGTADPDLLEEKLKAMRILENVELPSAFADVIVKPVNKPVTAKDAQNGVKTEQEEEKTAGEEEEDEVIPEPTVEPPKMVRMANLAVVGGHAVNGVAEIHSEIVKQDVFNDFVQLWPEKFQNKTNGVTPRRWIRFCNPYLSDIITNWIGTEDWVLNTEKVAELRKFADNEDLQSEWRAAKKKNKLKVVSLIKERTGYTVSPDAMFDIQIKRIHEYKRQLLNILGIVYRYKKMKEMSASEREKAFVPRVCIFGGKAFATYVQAKRIVKFITDVASTINHDPEIGDLLKVIFVPDYNVSVAELLIPASELSQHISTAGMEASGTSNMKFSMNGCVLIGTLDGANVEIREEVGEENFFLFGAKADQIVNLRKERAEGKFVPDPTFEEVKKFVGSGVFGSNSYDELIGSLEGNEGFGRADYFLVGKDFPSYIECQEKVDEAYRDQKRWTRMSIMNTAGSFKFSSDRTIHEYAKDIWNIKQVELP", "length": 962, "molWeight": 108585, "crc64": "54B3C4BBB076CFA5", "md5": "2AB3870FE13EBD8A66DC96EAA3755023"}}
{"primaryAccession": "Q9LIQ6", "text": "This is PHD finger protein ING1 protein, from Mouse-ear cress, contains 234 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [178, 227], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9LIQ6", "organism_name": "Mouse-ear cress", "protein_name": "PHD finger protein ING1", "length": 234, "firstPublicDate": "2011-10-19", "FUNCTION": "Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ING family", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSFAEEFEANLVSLAHVLQKKYALLRDLDKSLQENQRQNEQRCEKEIEDIRRGRAGNITPNTSLTKFSEEALDEQKHSVRIADEKVTLAMQAYDLVDMHVQQLDQYMKKSDEVIRKEKEAAAATLELENNGKAGNAGEGGRGGRKKTRLATAASTAAASTGMTSSNMDLDLPVDPNEPTYCICNQVSFGEMVACDNNACKIEWFHFGCVGLKEQPKGKWYCPECATVKKSRKGR", "length": 234, "molWeight": 26098, "crc64": "B24DADAA6FE12549", "md5": "286F744F448AB0B7A6DD1EAE9539A072"}}
{"primaryAccession": "Q9LJL4", "text": "This is Adenylate isopentenyltransferase 8, chloroplastic protein, from Mouse-ear cress, contains 330 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LJL4", "organism_name": "Mouse-ear cress", "protein_name": "Adenylate isopentenyltransferase 8, chloroplastic", "length": 330, "firstPublicDate": "2010-02-09", "FUNCTION": "Involved in cytokinin biosynthesis, Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the IPP transferase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQNLTSTFVSPSMIPITSPRLRLPPPRSVVPMTTVCMEQSYKQKVVVIMGATGSGKSCLSIDLATRFSGEIVNSDKIQFYDGLKVTTNQMSILERCGVPHHLLGELPPDDSELTTSEFRSLASRSISEITARGNLPIIAGGSNSFIHALLVDRFDPKTYPFSSETSISSGLRYECCFLWVDVSVSVLFEYLSKRVDQMMESGMFEELAGFYDPRYSGSAIRAHGIHKTIGIPEFDRYFSLYPPERKQKMSEWDQARKGAYDEAVQEIKENTWRLAKKQIERIMKLKSSGWDIQRLDATPSFGRSSREIWDNTVLDESIKVVKRFLVKDKV", "length": 330, "molWeight": 37322, "crc64": "4FEAD7F679317391", "md5": "A1E032FADA79C5A7E110689C4AE6C5FF"}}
{"primaryAccession": "Q9LPP4", "text": "This is Cyclin-dependent protein kinase inhibitor SMR1 protein, from Mouse-ear cress, contains 128 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LPP4", "organism_name": "Mouse-ear cress", "protein_name": "Cyclin-dependent protein kinase inhibitor SMR1", "length": 128, "firstPublicDate": "2012-07-11", "FUNCTION": "Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle (PubMed:17098811, PubMed:26546445), Cooperates with SIM and SMR2 to promote endoreplication during leaf development (PubMed:26546445), Specifically regulates endoreduplication in epidermal pavement cells to produce the cell size pattern (PubMed:20485493), Is necessary for giant cell formation (PubMed:20485493), Positive regulator of effector-triggered immunity (ETI) (PubMed:25455564)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDLELLQDLSKFNFPTPIKIRSKTSKTKKDEGDDDEDDLRCSTPTSQEHKIPAVVDSPPPPPRKPRPPPSAPSATAALMIRSCKRKLLVSTCEIIMNREEIDRFFSSVYNETSTTAKRRRSYPYCSRR", "length": 128, "molWeight": 14614, "crc64": "BF272EEE4EB97134", "md5": "B2C67BB66F04D968A191674AD2F23160"}}
{"primaryAccession": "Q9LRH6", "text": "This is GATA transcription factor 25 protein, from Mouse-ear cress, contains 309 amino acids, has 1 GATA-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [208, 267], "description": "GATA-type", "keyword_description": "Zinc finger", "textural_description": "GATA-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9LRH6", "organism_name": "Mouse-ear cress", "protein_name": "GATA transcription factor 25", "length": 309, "firstPublicDate": "2005-05-10", "FUNCTION": "Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the type IV zinc-finger family, Class C subfamily", "domain_description": {"GATA-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFGRHSIIPNNQIGTASASAGEDHVSASATSGHIPYDDMEEIPHPDSIYGAASDLIPDGSQLVAHRSDGSELLVSRPPEGANQLTISFRGQVYVFDAVGADKVDAVLSLLGGSTELAPGPQVMELAQQQNHMPVVEYQSRCSLPQRAQSLDRFRKKRNARCFEKKVRYGVRQEVALRMARNKGQFTSSKMTDGAYNSGTDQDSAQDDAHPEISCTHCGISSKCTPMMRRGPSGPRTLCNACGLFWANRGTLRDLSKKTEENQLALMKPDDGGSVADAANNLNTEAASVEEHTSMVSLANGDNSNLLGDH", "length": 309, "molWeight": 33261, "crc64": "DA80FFC90A6AACB5", "md5": "4BB55C80369FD55673179B6B16A939E4"}}
{"primaryAccession": "Q9LS90", "text": "This is Armadillo repeat-containing protein LFR protein, from Mouse-ear cress, contains 460 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LS90", "organism_name": "Mouse-ear cress", "protein_name": "Armadillo repeat-containing protein LFR", "length": 460, "firstPublicDate": "2014-11-26", "FUNCTION": "Involved in leaf and flower development (PubMed:18846319), Plays roles in leaf development partly by associating with AS2 and repressing KNAT1/BP transcription (PubMed:29775508), Required for the formation of anther cell layers and normal expression of genes that regulates anther development (PubMed:22461668)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQKRELGKSGGNSGGSSGPPAKRGRPFGSTSANSAAAAAAAAAADAMSPSALLGPSLLVHNSFVEQNNRRIVLALQSGLKSEVTWALNTLTLLSFKEKEDIRRDVMPLAKIAGLLDALLLIIDDWRDIALPKDLTRGTRVRTLGTNASVTGFGNEYDALASIQPPGSGIGSSAAEALGKKSTGKHQSSQWWMEEDGLFNLDDEGRSEKQMCAIAASNVIRNFSFMPDNEVVMAQHRHCLETVFQCIHDHMTEDEELVTNSLETIVNLAHLMDLRIFSSLKQSYININEKKAVQAVVGILNSSVKAWNCAAAELLGRLIINPDNEPFISPLIPQIHKRLIDLLSIQAVDAQAAAVGALYNLVEVNMDCRLKLASERWAVDRLLKVIKTPHPVPEVCRKAAMILENLVSEPQNRGLLLAYENAFAELLFQEGKYSDSFARILYELTARSNSRVASARGIWGM", "length": 460, "molWeight": 50112, "crc64": "81C85F88B2A4055A", "md5": "5BC5A80F6852BE1E52808D81CE96BEE7"}}
{"primaryAccession": "Q9LSP8", "text": "This is Calmodulin-binding transcription activator 6 protein, from Mouse-ear cress, contains 838 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LSP8", "organism_name": "Mouse-ear cress", "protein_name": "Calmodulin-binding transcription activator 6", "length": 838, "firstPublicDate": "2006-01-24", "FUNCTION": "Transcription activator that binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065), Binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3' (By similarity), Regulates transcriptional activity in response to calcium signals (Probable)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CAMTA family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDGDGLGRLIGSEIHGFHTLQDLDVQTMLEEAKSRWLRPNEIHAILCGRIILFDRKMLRNFRKDGHNWKKKKDGRTVKEAHEHLKVGNEERIHVYYAHGEDNTTFVRRCYWLLDKARENIVLVHYRDTQEAATTSGDSISSPISVSEQTFPNRVAAEDIDTVVRNHDISLHDINTLDWDELLVPTDLNNQSAPTVDNLSYFTEPLQNAANGTAEHGNATVADGSLDALLNDGPQSRESFGRWMNSFISESNGSLEDPSFEPMVMPRQDPLAPQAVFHSHSNIPEQVFNITDVSPAWAYSSEKTKILVTGFLHDSYQHLERSNLYCVCGDFCVPAEYLQAGVYRCIIPPHSPGMVNLYLSADGHKPISQCFRFEHRAVPVLDKTVPEDNQDSKWEEFEFQVRLSHLLFTSSNKLNVLSSKISPHNLRDAKKLASKTNHLLNSWAYLVKSIQGNKVSFDQAKDHLFELSLKNRLKEWLMEKVLEGRNTLDYDSKGLGVIHLCASLGYTWSVQLFSLSGLSLNFRDKQGWTALHWAAYYGREKMVAALLSAGARPNLVTDSTKDNLGGCMAADLAQQNGYDGLAAYLAEKCLVAQFRDMKIAGNITGDLEACKAEMLNQGTLPEDEQSLKDALAAYRTAAEAAARIQGAFREKALKAARSSVIQFANKEEEAKSIIAAMKIQNAFRKYDTRRKIEAAYRIQCRFQTWKIRREYLNMRRQAIRIQAAFRGLQARRQYKKILWSVGVLEKAVLRWRQKRKGFRGLQVAAEEDSPGEAQEDFYKTSQRQAEERLERSVVRVQAMFRSKKAQQDYRRMKLTHEEAQVNHLTFLNLSFGKKNSNRR", "length": 838, "molWeight": 95382, "crc64": "A5DE9C698E633900", "md5": "A230E6BD4929899695BAB142337EDC79"}}
{"primaryAccession": "Q9LSR8", "text": "This is L-type lectin-domain containing receptor kinase I.9 protein, from Mouse-ear cress, contains 766 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LSR8", "organism_name": "Mouse-ear cress", "protein_name": "L-type lectin-domain containing receptor kinase I.9", "length": 766, "firstPublicDate": "2011-01-11", "FUNCTION": "Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "In the N-terminal section; belongs to the leguminous lectin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MARWLLQILIISSLHLSSVSSQQETSFVYESFLDRQNLYLDKSAIVLPSGLLQLTNASEHQMGHAFHKKPIEFSSSGPLSFSTHFVCALVPKPGFEGGHGIVFVLSPSMDFTHAESTRYLGIFNASTNGSSSYHVLAVELDTIWNPDFKDIDHNHVGIDVNSPISVAIASASYYSDMKGSNESINLLSGNPIQVWVDYEGTLLNVSVAPLEVQKPTRPLLSHPINLTELFPNRSSLFAGFSAATGTAISDQYILWWSFSIDRGSLQRLDISKLPEVPHPRAPHKKVSTLIILLPVCLAILVLAVLAGLYFRRRRKYSEVSETWEKEFDAHRFSYRSLFKATKGFSKDEFLGKGGFGEVYRGNLPQGREIAVKRVSHNGDEGVKQFVAEVVSMRCLKHRNLVPLFGYCRRKRELLLVSEYMPNGSLDEHLFDDQKPVLSWSQRLVVVKGIASALWYLHTGADQVVLHRDVKASNIMLDAEFHGRLGDFGMARFHEHGGNAATTAAVGTVGYMAPELITMGASTGTDVYAFGVFMLEVTCGRRPVEPQLQVEKRHMIKWVCECWKKDSLLDATDPRLGGKFVAEEVEMVMKLGLLCSNIVPESRPTMEQVVLYLNKNLPLPDFSPYTLGIGTFAPVLVDASSLVVSSASWSLSGPSMSSSSPNHSPYAWQSTDQPWGQTIDTKNSLHIVAEPEKPSPAVKMVTLPAEDPQSNHSSISSQRVQPVKREKRRLHQILVAFPWINKQYFKLGLPKHIVHVSLFFFLQLARL", "length": 766, "molWeight": 85319, "crc64": "F47912152E08F505", "md5": "8867482D1BD4E8942B6B18C1281F25AA"}}
{"primaryAccession": "Q9LSZ9", "text": "This is Long chain base biosynthesis protein 2a protein, from Mouse-ear cress, contains 489 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LSZ9", "organism_name": "Mouse-ear cress", "protein_name": "Long chain base biosynthesis protein 2a", "length": 489, "firstPublicDate": "2012-10-03", "FUNCTION": "Serine palmitoyltransferase (SPT), The heterodimer formed with LCB1 constitutes the catalytic core, Involved in the regulation of the programmed cell death (PCD) signaling pathway, Plays an important role during male gametogenesis and embryogenesis", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MITIPYLTAVSTYFSYGLLFAFGQLRDFFRRFIDWWFTSNLQGYAPICLGHEDFYIRRLYHRIQDCFERPISSAPDAWFDVVERYSNDNNKTLKRTTKTSRCLNLGSYNYLGFGSFDEYCTPRVIESLKKFSASTCSSRVDAGTTSVHAELEECVTRFVGKPAAVVFGMGYATNSAIIPVLIGKGGLIISDSLNHSSIVNGARGSGATIRVFQHNTPSHLERVLREQIAEGQPRTHRPWKKIIVVVEGIYSMEGEICHLPEVVAICKKYKAYVYLDEAHSIGAIGKTGKGICELLGVDTADVDVMMGTFTKSFGSCGGYIAGSKELIQYLKHQCPAHLYATSIPTPSAQQIISAIKVILGEDGSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMPIMLYNPAKIPAFSRECLRQKVAVVVVGFPATPLLLARARICISASHSREDLIRALKVISKVGDLSGIKYFPAEPKKIEQSKNDIKLD", "length": 489, "molWeight": 54290, "crc64": "00B396BB47D2E048", "md5": "4983A4ABBAF5CC0E414823B02F737D48"}}
{"primaryAccession": "Q9LU10", "text": "This is Protease Do-like 8, chloroplastic protein, from Mouse-ear cress, contains 448 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LU10", "organism_name": "Mouse-ear cress", "protein_name": "Protease Do-like 8, chloroplastic", "length": 448, "firstPublicDate": "2001-10-18", "FUNCTION": "Probable serine protease", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the peptidase S1C family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQVIASFCSKPNENEFVGRRQLLSSVCSKISQGDVVSHPPVSSVKVTQDWKSNLHELAVKSVPSTTRRILLTSLFMNLCFNPSRYLSALALGDPSVATVEDVSPTVFPAGPLFPTEGRIVQLFEKNTYSVVNIFDVTLRPQLKMTGVVEIPEGNGSGVVWDGQGYIVTNYHVIGNALSRNPSPGDVVGRVNILASDGVQKNFEGKLVGADRAKDLAVLKVDAPETLLKPIKVGQSNSLKVGQQCLAIGNPFGFDHTLTVGVISGLNRDIFSQTGVTIGGGIQTDAAINPGNSGGPLLDSKGNLIGINTAIFTQTGTSAGVGFAIPSSTVLKIVPQLIQFSKVLRAGINIELAPDPVANQLNVRNGALVLQVPGKSLAEKAGLHPTSRGFAGNIVLGDIIVAVDDKPVKNKAELMKILDEYSVGDKVTLKIKRGNEDLELKISLEEKSS", "length": 448, "molWeight": 47493, "crc64": "A986FC1387670AFF", "md5": "C9D218638EE3B69D67918D4E168EC6CB"}}
{"primaryAccession": "Q9LUT2", "text": "This is S-adenosylmethionine synthase 4 protein, from Mouse-ear cress, contains 393 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LUT2", "organism_name": "Mouse-ear cress", "protein_name": "S-adenosylmethionine synthase 4", "length": 393, "firstPublicDate": "2009-02-10", "FUNCTION": "Catalyzes the formation of S-adenosylmethionine from methionine and ATP, The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the AdoMet synthase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MESFLFTSESVNEGHPDKLCDQISDAILDACLEQDPESKVACETCTKTNMVMVFGEITTKANVDYEQIVRKTCREIGFVSADVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKKPEEVGAGDQGHMFGYATDETPELMPLTHVLATKLGAKLTEVRKNGTCPWLRPDGKTQVTIEYINESGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASGLARRVIVQVSYAIGVPEPLSVFVDSYGTGKIPDKEILEIVKESFDFRPGMISINLDLKRGGNGRFLKTAAYGHFGRDDADFTWEVVKPLKSNKVQA", "length": 393, "molWeight": 42796, "crc64": "70034EC2B5E81867", "md5": "AAA74175E4746FE41AF861BF92D33000"}}
{"primaryAccession": "Q9LVA0", "text": "This is BAG family molecular chaperone regulator 7 protein, from Mouse-ear cress, contains 446 amino acids, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LVA0", "organism_name": "Mouse-ear cress", "protein_name": "BAG family molecular chaperone regulator 7", "length": 446, "firstPublicDate": "2012-02-22", "FUNCTION": "Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses, Necessary for the proper maintenance of the unfolded protein response (UPR) during heat and cold tolerance", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTLFHRLDLIDPYTCTPLIVRETSIVEPSSLFLGFPSFIDEDIEDLFEFSSPNPLDLFETVTDLVKIKKSPSSCKYKVIRRRLEPEYPLKYLCDRVSDLESKFDRLVSPKSDRKYTLTKEIKGSGERKYKWEAEIQGPLERKYKLEAEIEGSGERKYRWTTEIKGGKKDEEGLKLAALKKEKAKAKAIAAAEAEKKKNKNKKKSYNWTTEVKSERENGEVSHTYIIKATTGGEKKKKHEEKEKKEKIETKSKKKEKTRVVVIEEEEEEDDESSEHGAIVLRKAFSRRNGAVRTKKGKNKEMPPEYAAVMIQRAFKAYLIRRSKSLRALRDLAIAKTKLKELRASFHNFSYRRLIARDGEERQKFSEKIIVLLLTVDAIEGVDVMVRGAKRSMVDELEAMLDVVDPQPQGKSLSMRRRTFDMPDSLIRKEIAEGVTQIVQMLETEEE", "length": 446, "molWeight": 51567, "crc64": "95E3125F4CCC67F8", "md5": "832DA1CA35B206325BA2651001B5C97E"}}
{"primaryAccession": "Q9LVI9", "text": "This is Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic protein, from Mouse-ear cress, contains 426 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LVI9", "organism_name": "Mouse-ear cress", "protein_name": "Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic", "length": 426, "firstPublicDate": "2015-04-01", "FUNCTION": "Involved in pyrimidine base degradation, Catalyzes the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate and the reduction of thymine to 5,6-dihydrothymine (DHT), Involved in the recycling of nitrogen from nucleobases to general nitrogen metabolism", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the dihydropyrimidine dehydrogenase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASMSFALNRFSGLSSKTTLSADFDPSSRRSFLPPTRVGLKISSAAESEPDLSVTVNGLKMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVIAKTVSLDASKVINVTPRYARLRTGSNGSAKTDVIGWQNIELISDRPLETMLKEFERLKKEYPDRILIASVMEEYNKTAWEELIDRVEQTGVDALEINFSCPHGMPERRMGAAVGQDCALLDEVCGWINAKATVPVWAKMTPNITDITEPARVSLKSGCEGIAAINTIMSVMGIDMKTLRPEPCVEGYSTPGGYSYKAVRPIALAKVMNIAKMMKSEFSEDRSLSGIGGVETGYDAAEFILLGSNTVQVCTGVMMHGYGHVKTLCAELKDFMKQHNFSTIEEFRGHSLQYFTTHTDLVKRQKEAVEQRKAEKRGLKSDKDWTGDGFVKETESMVSN", "length": 426, "molWeight": 46847, "crc64": "0DA1BAEE08F90A18", "md5": "B7DC6E5483C41B487DA448B42BF2B594"}}
{"primaryAccession": "Q9LXU0", "text": "This is CLAVATA3/ESR (CLE)-related protein 40 protein, from Mouse-ear cress, contains 80 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LXU0", "organism_name": "Mouse-ear cress", "protein_name": "CLAVATA3/ESR (CLE)-related protein 40", "length": 80, "firstPublicDate": "2010-11-30", "FUNCTION": "Extracellular signal peptide secreted by differentiated root cells that regulates root cell fate, Acts with ACR4 as a ligand-receptor pair in a signal transduction pathway, coordinating movement of the root tip and organization of cell divisions in the root meristem, Promotes cell differentiation in the distal root meristem in a dose-dependent manner, especially the transition from columella stem cells (CSC) daughters into columella cells (CCs), Induces ACR4 expression in root quiescent center (QC), Involved in WUX5 QC-specific expression pattern regulation, Regulates the transition of protophloem cells from proliferation to differentiation, thus impinging on postembryonic growth capacity of the root meristem; this signaling pathway requires CRN and CLV2 (PubMed:28607033)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the CLV3/ESR signal peptide family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAMKYKGSVFIILVILLLSSSLLAHSSSTKSFFWLGETQDTKAMKKEKKIDGGTANEVEERQVPTGSDPLHHKHIPFTP", "length": 80, "molWeight": 8856, "crc64": "907BC07E42C7EA09", "md5": "7CD4D86F7305D0D2E66126C515D6A48D"}}
{"primaryAccession": "Q9LY62", "text": "This is Glycosylinositol phosphorylceramide mannosyl transferase 1 protein, from Mouse-ear cress, contains 334 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LY62", "organism_name": "Mouse-ear cress", "protein_name": "Glycosylinositol phosphorylceramide mannosyl transferase 1", "length": 334, "firstPublicDate": "2014-10-29", "FUNCTION": "Mannosyl transferase (ManT) required for the biosynthesis of mannose-carrying glycosylinositol phosphorylceramides (GIPCs) (PubMed:27895225), Maybe involved in cell-cell adhesion that maintains the integrity of organs by providing mechanical strength and facilitating the movement of metabolites throughout the plant during development (PubMed:16045474), Prevents abscisic acid- (ABA-) mediated effects on development (e,g, cell size, flowering time, senescence), Probably implicated in beta-(1,4)-galactan biosynthesis thus being a cell-wall synthesis-related (CWSR) protein (PubMed:17426055, PubMed:20687615)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the glycosyltransferase 64 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGGGEVSKEMGACSLAYRRGDQKLRKFVTARSTKFLLFCCIAFVLVTIVCRSSRPWVNSSIAVADRISGSRKGYTLLMNTWKRYDLLKKSVSHYASCSRLDSIHIVWSEPNPPSESLKEYLHNVLKKKTRDGHEVELRFDINKEDSLNNRFKEIKDLKTDAVFSIDDDIIFPCHTVDFAFNVWESAPDTMVGFVPRVHWPEKSNDKANYYTYSGWWSVWWSGTYSMVLSKAAFFHKKYLSLYTNSMPASIREFTTKNRNCEDIAMSFLIANATNAPAIWVKGKIYEIGSTGISSIGGHTEKRTHCVNRFVAEFGKMPLVYTSMKAVDSRNLWFW", "length": 334, "molWeight": 38300, "crc64": "2E41E5600D36B5B9", "md5": "31BE5C024902E83829C9D1A2CA711856"}}
{"primaryAccession": "Q9LYT1", "text": "This is Polyamine oxidase 3 protein, from Mouse-ear cress, contains 488 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LYT1", "organism_name": "Mouse-ear cress", "protein_name": "Polyamine oxidase 3", "length": 488, "firstPublicDate": "2008-10-14", "FUNCTION": "Flavoenzyme involved in polyamine back-conversion (PubMed:18583528, PubMed:20532512, PubMed:21081665), Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine, spermidine and their acetyl derivatives (PubMed:18583528, PubMed:20532512, PubMed:21081665), Substrate preference is spermidine > spermine > N(1)-acetylspermidine > N(1)-acetylspermine (PubMed:18583528), Plays an important role in the regulation of polyamine intracellular concentration (Probable), Involved in the production of hydrogen peroxide during pollen tube growth (PubMed:20626657), Hydrogen peroxide triggers the opening of the hyperpolarization-activated calcium permeable channels in pollen, and thus regulates pollen tube growth (PubMed:20626657)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the flavin monoamine oxidase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MESGGKTNRQLRKAICVSTDEKMKKKRSPSVIVIGGGMAGISAARTLQDASFQVVVLESRDRIGGRVHTDYSFGFPVDLGASWLHGVCKENPLAAVIGRLGLPLYRTSGDNSVLYDHDLESYALFDKAGNQVSQELVTKVGENFEHILEEICKVRDEQDEDMSIAQAFSIVFKRNPELRLEGLAHNVLQWYLCRMEGWFAADAETISAKCWDQEELLPGGHGLMVRGYRPVINTLSKGLDIRLSHRITKISRRYSGVKVTTEKGDTFVADAAVIALPLGVLKSGMITFEPKLPQWKQEAINDLGVGIENKIILNFDNVFWPNVEFLGVVAETSYGCSYFLNLHKATSHPVLVYMPAGQLARDIEKKSDEAAANFAFSQLQKILPDASSPINYLVSRWGSDINSLGSYSYDIVNKPHDLYERLRVPLDNLFFAGEATSSSYPGSVHGAYSTGVLAAEDCRMRVLERYGELEHEMEEEAPASVPLLISRM", "length": 488, "molWeight": 54132, "crc64": "1EC37D18794A2BD4", "md5": "73B5E34A55E716F276FA1C8EAA05D3E8"}}
{"primaryAccession": "Q9LZ78", "text": "This is Cyclin-dependent protein kinase inhibitor SIM protein, from Mouse-ear cress, contains 127 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LZ78", "organism_name": "Mouse-ear cress", "protein_name": "Cyclin-dependent protein kinase inhibitor SIM", "length": 127, "firstPublicDate": "2012-07-11", "FUNCTION": "Cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle (PubMed:10952891, PubMed:11882294, PubMed:17098811, PubMed:17764505, PubMed:19717615, PubMed:20194967), Inhibits the kinase activity of CYCD3-1/CDKA-1, CYCD2-1/CDKA-1 and CYCB1-1/CDKB1-1 complexes in a dose dependent manner (PubMed:26546445), Cooperates with SMR1 and SMR2 to promote endoreplication during leaf development (PubMed:26546445), Required for normal trichome endoreplicating cell cycles (PubMed:10952891, PubMed:11882294, PubMed:17098811, PubMed:17764505, PubMed:19717615, PubMed:20194967), Positive regulator of effector-triggered immunity (ETI) (PubMed:25455564)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDLDLIQDLPILNFPPAIKIRANTNRDDDGGGCTTPTSSDHKIPPTTATTPPPPPQKPRPPSTPSSLGIRSCKRKLMTSLSKYEIIVNKDEIERFFSSVYNQTMASSTTTAITVAKRRRSFRSCSRR", "length": 127, "molWeight": 14091, "crc64": "3CD095F760CBE781", "md5": "38915B26D6EA4B60309EA9853A03D344"}}
{"primaryAccession": "Q9LZS3", "text": "This is 1,4-alpha-glucan-branching enzyme 2-2, chloroplastic/amyloplastic protein, from Mouse-ear cress, contains 805 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LZS3", "organism_name": "Mouse-ear cress", "protein_name": "1,4-alpha-glucan-branching enzyme 2-2, chloroplastic/amyloplastic", "length": 805, "firstPublicDate": "2012-01-25", "FUNCTION": "Catalyzes the formation of the alpha-1,6-glucosidic linkages in starch by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the glycosyl hydrolase 13 family, GlgB subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVVIHGVSLTPRFTLPSRPLNTGFNAGNSTLSFFFKKHPLSRKIFAGKQSAEFDSSSQAISASEKVLVPDNLDDDPRGFSQIFDLESQTMEYTEAVRTEDQTMNVVKERGVKPRIVPPPGDGKKIYEIDPMLRTYNNHLDYRYGQYKRLREEIDKYEGGLEAFSRGYEKLGFSRSDAGITYREWAPGAKAASLIGDFNNWNSNADIMTRNEFGVWEIFLPNNTDGSPAIPHGSRVKIRMDTPSGIKDSIPAWIKFSVQAPGEIPFNGIYYDPPEEEKYVFKHPQPKRPKSLRIYEAHVGMSSTEPMVNTYANFRDDVLPRIKKLGYNAVQIMAIQEHSYYASFGYHVTNFFAPSSRCGTPEELKSLIDRAHELGLVVLMDIVHSHASKNTLDGLNMFDGTDAHYFHSGPRGYHWMWDSRLFNYGSWEVLRYLLSNARWWLEEYKFDGFRFDGVTSMMYTHHGLSVGFTGNYTEYFGLETDVDAVNYLMLVNDMIHGLYPEAITVGEDVSGMPTFCIPVQDGGVGFDYRLHMAIADKWIEMLKKRDEDWQMGDIIYTLTNRRWSEKCISYAESHDQALVGDKTIAFWLMDKDMYDFMAVDRPSTPLIDRGIALHKMIRLITMGLGGEGYLNFMGNEFGHPEWIDFPRGEQRLSDGSVIPGNNFSYDKCRRRFDLGDADYLRYRGLQEFDQAMQHLEENYGFMTSEHQFISRKDEADRVIVFERGDLVFVFNFHWTSSYFDYRIGCSKPGKYKIVLDSDDPLFGGFNRLDRKAEYFTYDGLYDERPCSFMVYAPCRTAVVYALANHD", "length": 805, "molWeight": 92591, "crc64": "7CE130BD9C4941D0", "md5": "BE823D18FEA3AFEC0EC5FF396322FE47"}}
{"primaryAccession": "Q9M021", "text": "This is L-type lectin-domain containing receptor kinase VI.2 protein, from Mouse-ear cress, contains 682 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M021", "organism_name": "Mouse-ear cress", "protein_name": "L-type lectin-domain containing receptor kinase VI.2", "length": 682, "firstPublicDate": "2009-02-10", "FUNCTION": "Involved in resistance response to the pathogenic bacteria Pseudomonas syringae", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "In the N-terminal section; belongs to the leguminous lectin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGTQRSMFIVSFLFKLFLFLSVHVRAQRTTTNFAFRGFNGNQSKIRIEGAAMIKPDGLLRLTDRKSNVTGTAFYHKPVRLLNRNSTNVTIRSFSTSFVFVIIPSSSSNKGFGFTFTLSPTPYRLNAGSAQYLGVFNKENNGDPRNHVFAVEFDTVQGSRDDNTDRIGNDIGLNYNSRTSDLQEPVVYYNNDDHNKKEDFQLESGNPIQALLEYDGATQMLNVTVYPARLGFKPTKPLISQHVPKLLEIVQEEMYVGFTASTGKGQSSAHYVMGWSFSSGGERPIADVLILSELPPPPPNKAKKEGLNSQVIVMIVALSAVMLVMLVLLFFFVMYKKRLGQEETLEDWEIDHPRRLRYRDLYVATDGFKKTGIIGTGGFGTVFKGKLPNSDPIAVKKIIPSSRQGVREFVAEIESLGKLRHKNLVNLQGWCKHKNDLLLIYDYIPNGSLDSLLYTVPRRSGAVLSWNARFQIAKGIASGLLYLHEEWEKIVIHRDVKPSNVLIDSKMNPRLGDFGLARLYERGTLSETTALVGTIGYMAPELSRNGNPSSASDVFAFGVLLLEIVCGRKPTDSGTFFLVDWVMELHANGEILSAIDPRLGSGYDGGEARLALAVGLLCCHQKPASRPSMRIVLRYLNGEENVPEIDDEWGYSKSSRSEFGSKLVGYVSSTSITRVSSTSRISQ", "length": 682, "molWeight": 75868, "crc64": "C19750EC2E8E470F", "md5": "57B85982CCE95DBB3B5F7479011B03D3"}}
{"primaryAccession": "Q9M1S3", "text": "This is Probable RNA-binding protein ARP1 protein, from Mouse-ear cress, contains 261 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M1S3", "organism_name": "Mouse-ear cress", "protein_name": "Probable RNA-binding protein ARP1", "length": 261, "firstPublicDate": "2015-05-27", "FUNCTION": "Probable RNA-binding protein involved in the regulation of abscisic acid (ABA) response during seed germination, May regulate transcript levels of several germination-responsive genes under ABA", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTTSNNVNGCFGDTKLTKVFVGGLAWDTHKEAMYDHFIKYGDILEAVIISDKLTRRSKGYGFVTFKDAKAATRACEDSTPIINGRRANCNLASLGGRLRKSPTMTSPQQGPKNGNRATPPHVGNHSQWYYPSGFTNQQHQQQNHQAVPFYGYPSAYVAPNMTFNQKVGYVGGTYMNGYYAQMQPQPQSQPQPQYYHHHMYGGGRVMVGAASPMVPFYTVYPYHQSQAIGFPQPSFSKPLSFSTPPISGTVGGESIQKKAIH", "length": 261, "molWeight": 28857, "crc64": "337ED1608927B169", "md5": "6D14BFC5D8DBF03F52D82574BB42EB0D"}}
{"primaryAccession": "Q9M3D8", "text": "This is L-type lectin-domain containing receptor kinase I.3 protein, from Mouse-ear cress, contains 664 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M3D8", "organism_name": "Mouse-ear cress", "protein_name": "L-type lectin-domain containing receptor kinase I.3", "length": 664, "firstPublicDate": "2011-01-11", "FUNCTION": "Involved in resistance response to the pathogenic fungus Alternaria brassicicola", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "In the N-terminal section; belongs to the leguminous lectin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MACRLYLALIFSCVYLICLSSQQETGFVYNGFEQADLFIDGIAKILPDGLLQLTNTTELQMGHAFFKKPFDFDPSSSLSFYTHFVCALVPPKLGADGGHGIVFVVSPSIDLSHAYATQYLGVFSNLTNGTSSSHLLAIELDTVKTVEFNELEKPHVGIDLNSPISVESALPSYFSNALGKNISINLLSGEPIQVWVDYDGSFLNVTLAPIEIKKPNQPLISRAINLSEIFQEKMYVGFSSSTGNLLSNHYILGWSFSRRKEQLQSLNLSTLPRVPLPKEEKKKLSPLLIGLVILLVIPVVMVLGGVYWYRRKKYAEVKEWWEKEYGPHRFSYKSLYKATNGFRKDCRVGKGGFGEVYKGTLPGGRHIAVKRLSHDAEQGMKQFVAEVVTMGNLQHRNLVPLLGYCRRKCELLLVSEYMPNGSLDQYLFHEGNPSPSWYQRISILKDIASALSYLHTGTKQVVLHRDIKASNVMLDSEFNGRLGDFGMAKFHDRGTNLSATAAVGTIGYMAPELITMGTSMKTDVYAFGAFLLEVICGRRPVEPELPVGKQYLVKWVYECWKEACLFKTRDPRLGVEFLPEEVEMVLKLGLLCTNAMPESRPAMEQVVQYLNQDLPLPIFSPSTPGIGAFMPVSMEALSAIGVSSVRNSSVSMFVTHTILDGHGR", "length": 664, "molWeight": 73910, "crc64": "29A6D323710F1FF0", "md5": "1A03527A0B35B4B8EE4F543B68F9B016"}}
{"primaryAccession": "Q9M4A1", "text": "This is Meiotic recombination protein SPO11-2 protein, from Mouse-ear cress, contains 383 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M4A1", "organism_name": "Mouse-ear cress", "protein_name": "Meiotic recombination protein SPO11-2", "length": 383, "firstPublicDate": "2008-09-02", "FUNCTION": "Component of a topoisomerase 6 complex specifically required for meiotic recombination (PubMed:17018031, PubMed:17965269, PubMed:26917763), Together with MTOPVIB, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (PubMed:26917763, PubMed:19763177), The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles (PubMed:17018031, PubMed:17965269, PubMed:26917763)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TOP6A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEESSGLSSMKFFSDQHLSYADILLPHEARARIEVSVLNLLRILNSPDPAISDLSLINRKRSNSCINKGILTDVSYIFLSTSFTKSSLTNAKTAKAFVRVWKVMEICFQILLQEKRVTQRELFYKLLCDSPDYFSSQIEVNRSVQDVVALLRCSRYSLGIMASSRGLVAGRLFLQEPGKEAVDCSACGSSGFAITGDLNLLDNTIMRTDARYIIIVEKHAIFHRLVEDRVFNHIPCVFITAKGYPDIATRFFLHRMSTTFPDLPILVLVDWNPAGLAILCTFKFGSIGMGLEAYRYACNVKWIGLRGDDLNLIPEESLVPLKPKDSQIAKSLLSSKILQENYIEELSLMVQTGKRAEIEALYCHGYNYLGKYIATKIVQGKYI", "length": 383, "molWeight": 43126, "crc64": "08AB5FA102A1F189", "md5": "841784299C52FA492A8EB0E6897D1867"}}
{"primaryAccession": "Q9M670", "text": "This is Protein RESTRICTED TEV MOVEMENT 2 protein, from Mouse-ear cress, contains 366 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M670", "organism_name": "Mouse-ear cress", "protein_name": "Protein RESTRICTED TEV MOVEMENT 2", "length": 366, "firstPublicDate": "2014-05-14", "FUNCTION": "Required for the restriction of long-distance movement of the pathogenic tobacco etch virus (TEV) without causing a hypersensitive response or inducing systemic acquired resistance, Seems to not be involved in heat resistance", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the small heat shock protein (HSP20) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAARQQQKGTGFGVQYEDFVPKSEWKDQPEATILNIDLTGFAKEQMKVTYVHSSKMIRVTGERPLANRKWSRFNEVFTVPQNCLVDKIHGSFKNNVLTITMPKETITKVAYLPETSRTEAAALEKAAKLEEKRLLEESRRKEKEEEEAKQMKKQLLEEKEALIRKLQEEAKAKEEAEMRKLQEEAKAKEEAAAKKLQEEIEAKEKLEERKLEERRLEERKLEDMKLAEEAKLKKIQERKSVDESGEKEKILKPEVVYTKSGHVATPKPESGSGLKSGFGGVGEVVKSAEEKLGNLVEKEKKMGKGIMEKIRRKEITSEEKKLMMNVGVAALVIFALGAYVSYTFCSSSSSSSSSSPSSSSSSTKPE", "length": 366, "molWeight": 41340, "crc64": "5AECACE58D7E18FF", "md5": "BF9E2DBB66F46586EABE4B3F56E7EC0F"}}
{"primaryAccession": "Q9M7X9", "text": "This is Thioredoxin-like protein CITRX, chloroplastic protein, from Mouse-ear cress, contains 183 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M7X9", "organism_name": "Mouse-ear cress", "protein_name": "Thioredoxin-like protein CITRX, chloroplastic", "length": 183, "firstPublicDate": "2010-06-15", "FUNCTION": "Thiol-disulfide oxidoreductase that plays a role in proper chloroplast development, most likely through regulating plastid-encoded polymerase (PEP) dependent chloroplast transcription, Acts as a component of the transcriptionally active plastid chromosome that is required for plastid gene expression", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the thioredoxin family, Plant CITRX-type subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALVQSRTFPHLNTPLSPILSSLHAPSSLFIRREIRPVAAPFSSSTAGNLPFSPLTRPRKLLCPPPRGKFVREDYLVKKLSAQELQELVKGDRKVPLIVDFYATWCGPCILMAQELEMLAVEYESNAIIVKVDTDDEYEFARDMQVRGLPTLFFISPDPSKDAIRTEGLIPLQMMHDIIDNEM", "length": 183, "molWeight": 20670, "crc64": "1A1152A76B5DE8D7", "md5": "81BB32378F27190F1AC990DE5572DEFF"}}
{"primaryAccession": "Q9M8S2", "text": "This is Receptor-like kinase LIP2 protein, from Mouse-ear cress, contains 558 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M8S2", "organism_name": "Mouse-ear cress", "protein_name": "Receptor-like kinase LIP2", "length": 558, "firstPublicDate": "2016-06-08", "FUNCTION": "Involved in pollen tube guidance into micropyle, Participates in perception of the ovule-secreted peptide signal LURE1", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MHCFPCFSSPKNKKSSTTNETNDNNEPKPDDRRRAEETEEIEQSEGTSLKIFTFRELATATKNFRQECLLGEGGFGRVYKGTLKSTGQVVAVKQLDKHGLHGNKEFQAEVLSLGQLDHPNLVKLIGYCADGDQRLLVYDYISGGSLQDHLHEPKADSDPMDWTTRMQIAYAAAQGLDYLHDKANPPVIYRDLKASNILLDDDFSPKLSDFGLHKLGPGTGDKMMALSSRVMGTYGYSAPEYTRGGNLTLKSDVYSFGVVLLELITGRRALDTTRPNDEQNLVSWAQPIFRDPKRYPDMADPVLENKFSERGLNQAVAIASMCVQEEASARPLISDVMVALSFLSMPTEDGIPTTVPILSFKDKSMSIALSRHDSNLVSPPPELATEDDKSSTSSGEESSLESEKESVSKNEYKKKHEEEDSSMESDDESDSNSEHEKDQPPKPIDEKNQAQSLKIKYRYSWEDIDVNDERLSSKSSQKSNDESTSSRYDSDRDQDEKGKEEEEEEEAEEKHTHIEHIDSSKTDDDQSVYFDNDDDSGDDNGGSLHRIKSDVAIDSIKE", "length": 558, "molWeight": 62402, "crc64": "D6E8DB2A957432DB", "md5": "245112FF2EE6AD150DD087AB6C56B75A"}}
{"primaryAccession": "Q9M9E0", "text": "This is L-type lectin-domain containing receptor kinase S.1 protein, from Mouse-ear cress, contains 656 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M9E0", "organism_name": "Mouse-ear cress", "protein_name": "L-type lectin-domain containing receptor kinase S.1", "length": 656, "firstPublicDate": "2011-01-11", "FUNCTION": "Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici and to the pathogenic bacteria Pseudomonas syringae", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "In the N-terminal section; belongs to the leguminous lectin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSWQWRRRQWPSPLLLILIVLHLVSSSSAIDFLYNSFSSVTNRTDVILIEDSRVESTVISLINDSDPLSFGRVFYPQKLTIIPDPTRNPTRLSSFSTSFVFSILPDISTSPGFGLCFVLSNSTSPPNAISSQYFGLFTNATVRFNAPLLAVEFDTGRNSEVNDIDDNHVGIDLNNIESTTSVTAGYYDSVNGSFVRFNMRNGNNVRAWIDFDGPNFQINVSVAPVGVLRPRRPTLTFRDPVIANYVSADMYAGFSASKTNWNEARRILAWSLSDTGALREINTTNLPVFFLENSSSSLSTGAIAGIVIGCVVFVALIGFGGYLIWKKLMREEEEEEIEEWELEFWPHRFSYEELAAATEVFSNDRLLGSGGFGKVYRGILSNNSEIAVKCVNHDSKQGLREFMAEISSMGRLQHKNLVQMRGWCRRKNELMLVYDYMPNGSLNQWIFDNPKEPMPWRRRRQVINDVAEGLNYLHHGWDQVVIHRDIKSSNILLDSEMRGRLGDFGLAKLYEHGGAPNTTRVVGTLGYLAPELASASAPTEASDVYSFGVVVLEVVSGRRPIEYAEEEDMVLVDWVRDLYGGGRVVDAADERVRSECETMEEVELLLKLGLACCHPDPAKRPNMREIVSLLLGSPQEDLLTGLTPAAAAADSTAAHA", "length": 656, "molWeight": 73146, "crc64": "AE5779A21D8D9EE2", "md5": "794845E9360621797A3CFF0056529834"}}
{"primaryAccession": "Q9M9F0", "text": "This is VQ motif-containing protein 9 protein, from Mouse-ear cress, contains 311 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M9F0", "organism_name": "Mouse-ear cress", "protein_name": "VQ motif-containing protein 9", "length": 311, "firstPublicDate": "2015-03-04", "FUNCTION": "Functions as a negative regulator of salt stress response, Functions as repressor of WRKY8 transcription factor by decreasing the DNA-binding activity of WRKY8 and acts antagonistically with WRKY8 to regulate sodium and potassium homeostasis under salt stress", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDKSCNSSGDSSAVSASATSSTGNNTTNRDHYLRQLNKLSHKISKPTNSSSSVSVANREIDLPPPPPLQINQGNLHQHQPPVYNINKNDFRDVVQKLTGSPAHERISAPPQQPIHHPKPQQSSRLHRIRPPPLVHVINRPPGLLNDALIPQGSHHMNQNWTGVGFNLRPTAPLSPLPPLPPVHAAAESPVSSYMRYLQNSMFAIDSNRKEFSGLSPLAPLVSPRWYQQQENAPPSQHNSFPPPHPPPPSSAVSQTVPTSIPAPPLFGCSSSPKSPYGLLSPSILLSPSSGQLGFPVSPTTVPLPSPKYKGH", "length": 311, "molWeight": 33577, "crc64": "B32D409EA21EF6C2", "md5": "85998B49B2A3D90204772344202DFB7E"}}
{"primaryAccession": "Q9MAQ0", "text": "This is Granule-bound starch synthase 1, chloroplastic/amyloplastic protein, from Mouse-ear cress, contains 610 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9MAQ0", "organism_name": "Mouse-ear cress", "protein_name": "Granule-bound starch synthase 1, chloroplastic/amyloplastic", "length": 610, "firstPublicDate": "2003-03-25", "FUNCTION": "Required for the synthesis of amylose (PubMed:25710501), Destroyed as it is released from the starch granules during the night (PubMed:15347792), The circadian expression is controlled by CCA1 and LHY transcription factors (PubMed:12777053)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the glycosyltransferase 1 family, Bacterial/plant glycogen synthase subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATVTASSNFVSRTSLFNNHGASSCSDVAQITLKGQSLTHCGLRSFNMVDNLQRRSQAKPVSAKSSKRSSKVKTAGKIVCEKGMSVIFIGAEVGPWSKTGGLGDVLGGLPPALAARGHRVMTICPRYDQYKDAWDTCVVVQIKVGDKVENVRFFHCYKRGVDRVFVDHPIFLAKVVGKTGSKIYGPITGVDYNDNQLRFSLLCQAALEAPQVLNLNSSKYFSGPYGEDVVFVANDWHTALLPCYLKSMYQSRGVYMNAKVVFCIHNIAYQGRFAFDDYSLLNLPISFKSSFDFMDGYEKPVKGRKINWMKAAILEAHRVLTVSPYYAQELISGVDRGVELHKYLRMKTVSGIINGMDVQEWNPSTDKYIDIKYDITTVTDAKPLIKEALQAAVGLPVDRDVPVIGFIGRLEEQKGSDILVEAISKFMGLNVQMVILGTGKKKMEAQILELEEKFPGKAVGVAKFNVPLAHMITAGADFIIVPSRFEPCGLIQLHAMRYGTVPIVASTGGLVDTVKDGYTGFHIGRFNVKCEVVDPDDVIATAKAVTRAVAVYGTSAMQEMVKNCMDQDFSWKGPARLWEKVLLSLNVAGSEAGTEGEEIAPLAKENVATP", "length": 610, "molWeight": 66879, "crc64": "CF17F25BE12220DF", "md5": "BB7D6A4178491670F99A181335D1CF87"}}
{"primaryAccession": "Q9MBA2", "text": "This is Septum site-determining protein minD homolog, chloroplastic protein, from Mouse-ear cress, contains 326 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9MBA2", "organism_name": "Mouse-ear cress", "protein_name": "Septum site-determining protein minD homolog, chloroplastic", "length": 326, "firstPublicDate": "2011-04-05", "FUNCTION": "Together with ARC3 and MCD1, regulates FtsZ ring positioning in chloroplasts in an ARC6-dependent manner (PubMed:29967285, PubMed:28984364, PubMed:23936263), Calcium-dependent ATPase required for the correct placement of the plastid division site, Inhibits FtsZ filament and ring formation in the plastid, Mediates inhibition of plastid division (PubMed:28984364), In cooperation with MINE1, prevents FtsZ ring formation anywhere outside of the mid-plastids", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the ParA family, MinD subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASLRLFSTNHQSLLLPSSLSQKTLISSPRFVNNPSRRSPIRSVLQFNRKPELAGETPRIVVITSGKGGVGKTTTTANVGLSLARYGFSVVAIDADLGLRNLDLLLGLENRVNYTCVEVINGDCRLDQALVRDKRWSNFELLCISKPRSKLPMGFGGKALEWLVDALKTRPEGSPDFIIIDCPAGIDAGFITAITPANEAVLVTTPDITALRDADRVTGLLECDGIRDIKMIVNRVRTDMIKGEDMMSVLDVQEMLGLSLLGVIPEDSEVIRSTNRGFPLVLNKPPTLAGLAFEQAAWRLVEQDSMKAVMVEEEPKKRGFFSFFGG", "length": 326, "molWeight": 35690, "crc64": "BE7AEF4307167825", "md5": "BC73890BFFAEA49F2A6B57142ADC2B52"}}
{"primaryAccession": "Q9NH52", "text": "This is Histone-lysine N-methyltransferase mes-4 protein, from Caenorhabditis elegans, contains 898 amino acids, has 2 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [126, 214], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}, {"location": [303, 355], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9NH52", "organism_name": "Caenorhabditis elegans", "protein_name": "Histone-lysine N-methyltransferase mes-4", "length": 898, "firstPublicDate": "2003-03-28", "FUNCTION": "Histone methyltransferase, Dimethylates 'Lys-36' of histone H3, a specific tag for epigenetic transcriptional activation, Plays a central role in early development and is responsible for all H3 'Lys-36' dimethylation until about the 40-cell stage, Indirectly involved in the global inactivation of the X chromosomes in germline cells, possibly by excluding the mes-2-mes-3-mes-6 repressive Polycomb complex from the autosomes (PubMed:12077420, PubMed:16968818), Not related to transcription elongation (PubMed:12077420, PubMed:16968818), Required for small-RNA-induced H3K27 trimethylation (PubMed:26365259), May suppress sensitivity to RNAi (PubMed:16507136), May regulate the expression of genes required for vulval development (PubMed:16507136, PubMed:16710447)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, SET2 subfamily", "domain_description": {"PHD-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLPSSGDSSKENCAPQDGIVEKEGPNKPFKKKNVKQRNATPQGAGSETSSNAEDKQEEAPILTNAPKDIISMQIQETKAFLSEYEEFVDTDYPKTTFTHVPRKFLSVSPFTPIEADAEGEFLPDADSKCVICHEEKDKTGKSDLITCHGYINGEMDDGKRLLGNIPMFPCRSKFHASCMINYNSGGFHFQYAARLECQARLLCPLHCCNSCNLDHHKQSAYVGDIAECALCLRAFHLTSCYPSGGRDLNVSITIGGKVEKFEMIICPAHYLPGADVQFYNKHKKRKNAVTVVPKADVTMKSHIKACCVIGCEKSSNSKTIMCKTCCRSFHSGCREVETLNGKPIPDDQCESCVCGDPIPQNTLILAKWTDNSFWLALTLDWYKYPTGNRGNINFERLGYTVVQWLIPQENDKEKQPLMSIVPVSDIARLTKNYFSLAKNSTLRNLWEEKYEEQADTALKRCPYVCKTVFGRLRTSVYYKCEPKLEEYHNNEVCNCEGADRCTKLSCQYLADDYECPPSCSKKGVCHNRQVSMGIVSEKIKLAATLCKGYGVFAKGQIEKDEYICEYVGEIIDKAEKKRRLDSVSISRDFQANHYMMELHKGLTVDAARYGNISRYINHSCDPNAASFVTKVFVKKTKEGSLYDTRSYIRAIRTIDDGDEITFSYNMNNEENLPDCECGAENCMGTMGKAKREKPEVADSSEKAAKKNKSSKKKSVKNQNRKSQEAGKNGTASKKSEISPSKPSTSSASSTSFVQQASWPISQNKKNLKKNSNQPVADTGSTLSTSTELNFHEKPQELLSPVSSRSRAASSSTPRAQKSKSRRDDVESEAPPVKRATPSLQTIQETGKAIEFPATKSAITKARALSTQSVPSPHTVEVKVRAISTRGRVQKETKRFEPI", "length": 898, "molWeight": 100065, "crc64": "0FA6BC754FC9E295", "md5": "29CF009A3C54650945DB0A60B0344F73"}}
{"primaryAccession": "Q9NHB0", "text": "This is Gram-negative bacteria-binding protein 1 protein, from Fruit fly, contains 494 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NHB0", "organism_name": "Fruit fly", "protein_name": "Gram-negative bacteria-binding protein 1", "length": 494, "firstPublicDate": "2004-09-27", "FUNCTION": "Plays a key role in innate immunity by acting as a pattern recognition receptor for beta-1,3-glucan from fungi and lipopolysaccharide from Gram-negative bacteria (PubMed:10827089), Upon recognition of invading microorganism-derived products, acts upstream of protease spz processing enzyme SPE to activate the Toll pathway and to induce the expression of antimicrobial peptides drosomycin, cecropin and attacin (PubMed:10827089, PubMed:16399077)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the insect beta-1,3-glucan binding protein family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPGLCIGILLLIGFGCTTAYKIPTPTVELLETGFSVSIPDEEGVKVVAFNVNRNRNFTSFINEGQYNVRLTEPQNGRWTTNFSSVPLRSQDVLYLWTSVQHQKAVYQDLAQPLPVCNLGGEYRPRGCSPGDDDFTDDNQLSTEDSALEPTAPSVCEPSESQVSPQIGVSICKGQLLFEETFDQLNESLWIHDVRLPLDSKDAEFVLYDGKAKVHDGNLVIEPLLWSSYRPDLSIANSRLDLSERCTGTHNRIKECILHSTGSGPSGIMPPIVTPRISTKETFAFQYGRIEIRAKLPKGDWIVPLLLLEPLTEWYGQSGYESGQLRVALARGNSVLRMPRGKLVDGRSLYGGPVLSTDAHQREDLWLSKRKISHFGDDFHTYSLDWSSNRLLFSVDGQVYGEMLNGFTELDENPRWKQGGPMAPFDKMFYISLGVSVGGFGDFVDHLRTATYEKPWANYHPQAKLQFHQAQDQWLPTWKQPALKIDYVRVFATDN", "length": 494, "molWeight": 55531, "crc64": "95172030E5E61FAB", "md5": "F7A0D979FBF2195D14A81550D860D4EF"}}
{"primaryAccession": "Q9NJ98", "text": "This is Beta-1,3-glucan-binding protein 1 protein, from Tobacco hawkmoth, contains 487 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NJ98", "organism_name": "Tobacco hawkmoth", "protein_name": "Beta-1,3-glucan-binding protein 1", "length": 487, "firstPublicDate": "2004-09-27", "FUNCTION": "Involved in the recognition of invading microorganisms, Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade, Causes aggregation of invading microorganisms", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the insect beta-1,3-glucan binding protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLKSVFVLFLVNYLNSVRCLEVPDAKLEAIYPKGLRVSIPDDGYTLFAFHGKLNEEMEGLEAGHWSRDITKAKNGRWIFRDRNAKLKIGDKIYFWTYILKDGLGYRQDNGEWTVTGYVNEDGEPLDANFEPRSTASTAAPPQAGAGQAPGPSYPCELSVSEVSVPGFVCKGQMLFEDNFNKPLADGRIWTPEIMFPGEPDYPFNVYMKETDNLHVGNGNLVIKPMPLVTAFGEDAIWKTLDLSDRCTGLLGTAQCKRDPSDAIIVPPIVTAKINTKKTFAFKYGRVEISAKMPRGDWLVPLIQLEPVNKNYGIRNYVSGLLRVACVKGNTEYIKTLVGGPIMSEAEPYRTANLKEFISNEPWTNEFHNYTLEWSPDAITMAVDGIVYGRVTAPAGGFYKEANEQNVEAAARWIQGSNIAPFDDMFYISLGMDVGGVHEFPDEAINKPWKNTATKAMVNFWNARSQWNPTWLESEKALLVDYVRVYAL", "length": 487, "molWeight": 54567, "crc64": "3BA4869C5ADE934A", "md5": "9E0D6514130F7DB6E3FB3F4A25EDCFE2"}}
{"primaryAccession": "Q9NP55", "text": "This is BPI fold-containing family A member 1 protein, from Human, contains 256 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NP55", "organism_name": "Human", "protein_name": "BPI fold-containing family A member 1", "length": 256, "firstPublicDate": "2001-10-18", "FUNCTION": "Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC) (PubMed:25223608), Plays a role in the innate immune responses of the upper airways (PubMed:23499554, PubMed:23132494), Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P,aeruginosa and K,pneumoniae (PubMed:23499554, PubMed:23132494, PubMed:27145151), Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus (PubMed:24124190, PubMed:24043776), Plays a role in the airway inflammatory response after exposure to irritants (PubMed:11425234), May attract macrophages and neutrophils (PubMed:23132494)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the BPI/LBP/Plunc superfamily, Plunc family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFQTGGLIVFYGLLAQTMAQFGGLPVPLDQTLPLNVNPALPLSPTGLAGSLTNALSNGLLSGGLLGILENLPLLDILKPGGGTSGGLLGGLLGKVTSVIPGLNNIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDGLGPLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVIKV", "length": 256, "molWeight": 26713, "crc64": "EDF152FBC35315BC", "md5": "E34EC0F398281E829E9F5AEE6A0983E2"}}
{"primaryAccession": "Q9NP59", "text": "This is Solute carrier family 40 member 1 protein, from Human, contains 571 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NP59", "organism_name": "Human", "protein_name": "Solute carrier family 40 member 1", "length": 571, "firstPublicDate": "2004-06-07", "FUNCTION": "Transports Fe(2+) from the inside of a cell to the outside of the cell, playing a key role for maintaining systemic iron homeostasis (PubMed:15692071, PubMed:24304836, PubMed:22178646, PubMed:29599243, PubMed:30247984, PubMed:22682227, PubMed:29237594), Transports iron from intestinal, splenic, hepatic cells, macrophages and erythrocytes into the blood to provide iron to other tissues (By similarity), Controls therefore dietary iron uptake, iron recycling by macrophages and erythrocytes, and release of iron stores in hepatocytes (By similarity), When iron is in excess in serum, circulating HAMP/hepcidin levels increase resulting in a degradation of SLC40A1, thus limiting the iron efflux to plasma (PubMed:22682227, PubMed:29237594, PubMed:32814342)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the ferroportin (FP) (TC 2,A,100) family, SLC40A subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKLFACGPDAKEVRKENQANTSVV", "length": 571, "molWeight": 62542, "crc64": "E4D6B5594C904959", "md5": "8B6F9F9C6D31710BF735BBC549104103"}}
{"primaryAccession": "Q9NP95", "text": "This is Fibroblast growth factor 20 protein, from Human, contains 211 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NP95", "organism_name": "Human", "protein_name": "Fibroblast growth factor 20", "length": 211, "firstPublicDate": "2001-04-27", "FUNCTION": "Neurotrophic factor that regulates central nervous development and function", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the heparin-binding growth factors family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAPLAEVGGFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPERVPELYKDLLMYT", "length": 211, "molWeight": 23499, "crc64": "AB04608C16060CC1", "md5": "78BC69172791072E5939DA9E40F67314"}}
{"primaryAccession": "Q9NPF7", "text": "This is Interleukin-23 subunit alpha protein, from Human, contains 189 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NPF7", "organism_name": "Human", "protein_name": "Interleukin-23 subunit alpha", "length": 189, "firstPublicDate": "2006-10-31", "FUNCTION": "Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity (PubMed:11114383), Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4 (PubMed:32474165, PubMed:29287995, PubMed:33606986), This process leads to activation of several pathways including p38 MAPK or NF-kappa-B and promotes the production of pro-inflammatory cytokines such as interleukin-17A/IL17A (PubMed:12023369), In turn, participates in the early and effective intracellular bacterial clearance (PubMed:32474165), Promotes the expansion and survival of T-helper 17 cells, a CD4-positive helper T-cell subset that produces IL-17, as well as other IL-17-producing cells (PubMed:17676044)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the IL-6 superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLGSRAVMLLLLLPWTAQGRAVPGGSSPAWTQCQQLSQKLCTLAWSAHPLVGHMDLREEGDEETTNDVPHIQCGDGCDPQGLRDNSQFCLQRIHQGLIFYEKLLGSDIFTGEPSLLPDSPVGQLHASLLGLSQLLQPEGHHWETQQIPSLSPSQPWQRLLLRFKILRSLQAFVAVAARVFAHGAATLSP", "length": 189, "molWeight": 20730, "crc64": "51B5C0F188EC1B9F", "md5": "1BB2574987987CDF5B818F8BC99CA293"}}
{"primaryAccession": "Q9NPI8", "text": "This is Fanconi anemia group F protein protein, from Human, contains 374 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NPI8", "organism_name": "Human", "protein_name": "Fanconi anemia group F protein", "length": 374, "firstPublicDate": "2002-10-10", "FUNCTION": "DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function, May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MESLLQHLDRFSELLAVSSTTYVSTWDPATVRRALQWARYLRHIHRRFGRHGPIRTALERRLHNQWRQEGGFGRGPVPGLANFQALGHCDVLLSLRLLENRALGDAARYHLVQQLFPGPGVRDADEETLQESLARLARRRSAVHMLRFNGYRENPNLQEDSLMKTQAELLLERLQEVGKAEAERPARFLSSLWERLPQNNFLKVIAVALLQPPLSRRPQEELEPGIHKSPGEGSQVLVHWLLGNSEVFAAFCRALPAGLLTLVTSRHPALSPVYLGLLTDWGQRLHYDLQKGIWVGTESQDVPWEELHNRFQSLCQAPPPLKDKVLTALETCKAQDGDFEVPGLSIWTDLLLALRSGAFRKRQVLGLSAGLSSV", "length": 374, "molWeight": 42254, "crc64": "1F295CD1FBE6ED7D", "md5": "699102E232998FA050690CF7A29F4F7C"}}
{"primaryAccession": "Q9NQ79", "text": "This is Cartilage acidic protein 1 protein, from Human, contains 661 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NQ79", "organism_name": "Human", "protein_name": "Cartilage acidic protein 1", "length": 661, "firstPublicDate": "2004-07-19", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAPSADPGMSRMLPFLLLLWFLPITEGSQRAEPMFTAVTNSVLPPDYDSNPTQLNYGVAVTDVDHDGDFEIVVAGYNGPNLVLKYDRAQKRLVNIAVDERSSPYYALRDRQGNAIGVTACDIDGDGREEIYFLNTNNAFSGVATYTDKLFKFRNNRWEDILSDEVNVARGVASLFAGRSVACVDRKGSGRYSIYIANYAYGNVGPDALIEMDPEASDLSRGILALRDVAAEAGVSKYTGGRGVSVGPILSSSASDIFCDNENGPNFLFHNRGDGTFVDAAASAGVDDPHQHGRGVALADFNRDGKVDIVYGNWNGPHRLYLQMSTHGKVRFRDIASPKFSMPSPVRTVITADFDNDQELEIFFNNIAYRSSSANRLFRVIRREHGDPLIEELNPGDALEPEGRGTGGVVTDFDGDGMLDLILSHGESMAQPLSVFRGNQGFNNNWLRVVPRTRFGAFARGAKVVLYTKKSGAHLRIIDGGSGYLCEMEPVAHFGLGKDEASSVEVTWPDGKMVSRNVASGEMNSVLEILYPRDEDTLQDPAPLECGQGFSQQENGHCMDTNECIQFPFVCPRDKPVCVNTYGSYRCRTNKKCSRGYEPNEDGTACVGTLGQSPGPRPTTPTAAAATAAAAAAAGAATAAPVLVDGDLNLGSVVKESCEPSC", "length": 661, "molWeight": 71421, "crc64": "2EF75321817F0D01", "md5": "87C89B3768826144A688DBFF47E36252"}}
{"primaryAccession": "Q9NQ92", "text": "This is Coordinator of PRMT5 and differentiation stimulator protein, from Human, contains 184 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NQ92", "organism_name": "Human", "protein_name": "Coordinator of PRMT5 and differentiation stimulator", "length": 184, "firstPublicDate": "2008-05-20", "FUNCTION": "Histone-binding protein required for histone H4 methyltransferase activity of PRMT5, Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5, Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5, Involved in CCNE1 promoter repression, Plays a role in muscle cell differentiation by modulating the recruitment of PRMT5 to the promoter of genes involved in the coordination between cell cycle exit and muscle differentiation (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDLQAAGAQAQGAAEPSRGPPLPSARGAPPSPEAGFATADHSSQERETEKAMDRLARGTQSIPNDSPARGEGTHSEEEGFAMDEEDSDGELNTWELSEGTNCPPKEQPGDLFNEDWDSELKADQGNPYDADDIQESISQELKPWVCCAPQGDMIYDPSWHHPPPLIPYYSKMVFETGQFDDAED", "length": 184, "molWeight": 20066, "crc64": "38D3E94C34C48745", "md5": "B210A4AFC4E1439EA227451B32F1BC79"}}
{"primaryAccession": "Q9NQG5", "text": "This is Regulation of nuclear pre-mRNA domain-containing protein 1B protein, from Human, contains 326 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NQG5", "organism_name": "Human", "protein_name": "Regulation of nuclear pre-mRNA domain-containing protein 1B", "length": 326, "firstPublicDate": "2002-10-10", "FUNCTION": "Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2, Transcriptional regulator which enhances expression of CCND1, Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site, Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop, Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A, Promotes cell proliferation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the UPF0400 (RTT103) family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD", "length": 326, "molWeight": 36900, "crc64": "9057EEF6F3D18215", "md5": "89BC1450987EE9C7817B8426447C1C8E"}}
{"primaryAccession": "Q9NQG6", "text": "This is Mitochondrial dynamics protein MIEF1 protein, from Human, contains 463 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NQG6", "organism_name": "Human", "protein_name": "Mitochondrial dynamics protein MIEF1", "length": 463, "firstPublicDate": "2007-11-13", "FUNCTION": "Mitochondrial outer membrane protein which regulates mitochondrial fission, Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins, Regulates DNM1L GTPase activity and DNM1L oligomerization, Binds ADP and can also bind GDP, although with lower affinity, Does not bind CDP, UDP, ATP, AMP or GTP, Inhibits DNM1L GTPase activity in the absence of bound ADP, Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP, Does not require ADP for its function in recruiting DNM1L", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the SMCR7 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSPTRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEVQYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT", "length": 463, "molWeight": 51293, "crc64": "0824AD44305C234D", "md5": "C2C444132DC74D7F49C7EFBB1EF08F96"}}
{"primaryAccession": "Q9NRX1", "text": "This is RNA-binding protein PNO1 protein, from Human, contains 252 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NRX1", "organism_name": "Human", "protein_name": "RNA-binding protein PNO1", "length": 252, "firstPublicDate": "2007-01-09", "FUNCTION": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit, During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797), Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA (PubMed:25851604)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the PNO1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MESEMETQSARAEEGFTQVTRKGGRRAKKRQAEQLSAAGEGGDAGRMDTEEARPAKRPVFPPLCGDGLLSGKEETRKIPVPANRYTPLKENWMKIFTPIVEHLGLQIRFNLKSRNVEIRTCKETKDVSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEITDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADVKVHILGSFQNIKMARTAICNLILGNPPSKVYGNIRAVASRSADRF", "length": 252, "molWeight": 27924, "crc64": "DDF2285D95D3D232", "md5": "74EAAFEBCDB12A29BCFA0A7B38A9DD10"}}
{"primaryAccession": "Q9NSA0", "text": "This is Solute carrier family 22 member 11 protein, from Human, contains 550 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NSA0", "organism_name": "Human", "protein_name": "Solute carrier family 22 member 11", "length": 550, "firstPublicDate": "2006-05-16", "FUNCTION": "Antiporter that mediates the transport of conjugated steroids and other specific organic anions at the basal membrane of syncytiotrophoblast and at the apical membrane of proximal tubule epithelial cells, in exchange for anionic compounds (PubMed:10660625, PubMed:11907186, PubMed:15291761, PubMed:15037815, PubMed:15102942, PubMed:15576633, PubMed:17229912, PubMed:18501590, PubMed:26277985, PubMed:28027879), May be responsible for placental absorption of fetal-derived steroid sulfates such as estrone sulfate (E1S) and the steroid hormone precursor dehydroepiandrosterone sulfate (DHEA-S), as well as clearing waste products and xenobiotics from the fetus (PubMed:12409283), Maybe also be involved in placental urate homeostasis (PubMed:17229912), Facilitates the renal reabsorption of organic anions such as urate and derived steroid sulfates (PubMed:15037815, PubMed:17229912), Organic anion glutarate acts as conteranion for E1S renal uptake (PubMed:15037815, PubMed:17229912), Possible transport mode may also include DHEA-S/E1S exchange (PubMed:28027879), Also interacts with inorganic anions such as chloride and hydroxyl ions, therefore possible transport modes may include E1S/Cl(-), E1S/OH(-), urate/Cl(-) and urate/OH(-) (PubMed:17229912), Also mediates the transport of prostaglandin E2 (PGE2) and prostaglandin F2-alpha (PGF2-alpha) and may be involved in their renal excretion (PubMed:11907186), Also able to uptake anionic drugs, diuretics, bile salts and ochratoxin A (PubMed:10660625, PubMed:26277985), Mediates the unidirectional efflux of glutamate and aspartate (PubMed:28027879), Glutamate efflux down its transmembrane gradient may drive SLC22A11/OAT4-mediated placental uptake of E1S (PubMed:26277985)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFSKLLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQKSTAAQGNRQEAVTVESTSL", "length": 550, "molWeight": 59972, "crc64": "233BE6C4A520E58A", "md5": "1D829DF88B4D4B517F2A0BEB55A2F6ED"}}
{"primaryAccession": "Q9NT62", "text": "This is Ubiquitin-like-conjugating enzyme ATG3 protein, from Human, contains 314 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NT62", "organism_name": "Human", "protein_name": "Ubiquitin-like-conjugating enzyme ATG3", "length": 314, "firstPublicDate": "2005-03-15", "FUNCTION": "E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis, Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A), The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE), This step is required for the membrane association of ATG8-like proteins, The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt), Preferred substrate is MAP1LC3A, Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy, ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3, Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ATG3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGITGITEAVKEITLENKDNIRLQDCSALCEEEEDEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM", "length": 314, "molWeight": 35864, "crc64": "40EFE88DB5FE3EAB", "md5": "60AA39BF6D8E71A5336043C86E558CDB"}}
{"primaryAccession": "Q9NUB1", "text": "This is Acetyl-coenzyme A synthetase 2-like, mitochondrial protein, from Human, contains 689 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NUB1", "organism_name": "Human", "protein_name": "Acetyl-coenzyme A synthetase 2-like, mitochondrial", "length": 689, "firstPublicDate": "2003-04-23", "FUNCTION": "Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids (PubMed:16788062), Acetate is the preferred substrate (PubMed:16788062), Can also utilize propionate with a much lower affinity (By similarity), Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (By similarity), Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the ATP-dependent AMP-binding enzyme family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTVWDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINCEAWEWLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPDEILVVKRLPKTRSGKVMRRLLRKIITSEAQELGDTTTLEDPSIIAEILSVYQKCKDKQAAAK", "length": 689, "molWeight": 74857, "crc64": "66E84E39302AD08B", "md5": "A02274359DE7B8FA8B4ED28991531520"}}
{"primaryAccession": "Q9NUX5", "text": "This is Protection of telomeres protein 1 protein, from Human, contains 634 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NUX5", "organism_name": "Human", "protein_name": "Protection of telomeres protein 1", "length": 634, "firstPublicDate": "2004-07-19", "FUNCTION": "Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini, Is a component of the double-stranded telomeric DNA-binding TRF1 complex which is involved in the regulation of telomere length by cis-inhibition of telomerase, Also acts as a single-stranded telomeric DNA-binding protein and thus may act as a downstream effector of the TRF1 complex and may transduce information about telomere maintenance and/or length to the telomere terminus, Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection, Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways, Binds to two or more telomeric single-stranded 5'-TTAGGG-3' repeats (G-strand) and with high specificity to a minimal telomeric single-stranded 5'-TAGGGTTAG-3' sequence, Binds telomeric single-stranded sequences internally or at proximity of a 3'-end, Its activity is TERT dependent but it does not increase TERT activity by itself, In contrast, the ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the telombin family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSLVPATNYIYTPLNQLKGGTIVNVYGVVKFFKPPYLSKGTDYCSVVTIVDQTNVKLTCLLFSGNYEALPIIYKNGDIVRFHRLKIQVYKKETQGITSSGFASLTFEGTLGAPIIPRTSSKYFNFTTEDHKMVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPFPSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSMNSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLTANQHSDVICQSEPDDSFPSSGSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKPRRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKGRKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAPFLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDGTGVLEAYLMDSDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYNVTNGTDNQICYQIFDTTVAEDVI", "length": 634, "molWeight": 71442, "crc64": "123A12CABE708C91", "md5": "4CA0C09D48A975FE8AB06B23614D575A"}}
{"primaryAccession": "Q9NV88", "text": "This is Integrator complex subunit 9 protein, from Human, contains 658 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NV88", "organism_name": "Human", "protein_name": "Integrator complex subunit 9", "length": 658, "firstPublicDate": "2006-10-31", "FUNCTION": "Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable), Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, INTS9 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWSLKDGNAFLDKELKECSGHVFVDSVPEFCLPETELIDLSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTVQIGRLLMEELVNFIERVPKAQSASLWKNKDIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLVLTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSSVPLYFISPVANSSLEFSQIFAEWLCHNKQSKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFRQPCVVFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHLLQPPPRPAQPTSGKKRKRVSDDVPDCKVLKPLLSGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEMLRVRLRDLVLKFLQKF", "length": 658, "molWeight": 73814, "crc64": "81F1A24B99704684", "md5": "4DFE63E0C536B9C274164EAC64DB9347"}}
{"primaryAccession": "Q9NVH0", "text": "This is Exonuclease 3'-5' domain-containing protein 2 protein, from Human, contains 621 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NVH0", "organism_name": "Human", "protein_name": "Exonuclease 3'-5' domain-containing protein 2", "length": 621, "firstPublicDate": "2003-10-24", "FUNCTION": "Exonuclease that has both 3'-5' exoribonuclease and exodeoxyribonuclease activities, depending on the divalent metal cation used as cofactor (PubMed:29335528, PubMed:31127291), In presence of Mg(2+), only shows 3'-5' exoribonuclease activity, while it shows both exoribonuclease and exodeoxyribonuclease activities in presence of Mn(2+) (PubMed:29335528, PubMed:31127291), Acts as an exoribonuclease in mitochondrion, possibly by regulating ATP production and mitochondrial translation (PubMed:29335528), Also involved in the response to DNA damage (PubMed:26807646, PubMed:31255466), Acts as 3'-5' exodeoxyribonuclease for double-strand breaks resection and efficient homologous recombination (PubMed:20603073, PubMed:26807646), Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks (PubMed:26807646), Also involved in response to replicative stress: recruited to stalled forks and is required to stabilize and restart stalled replication forks by restraining excessive fork regression, thereby suppressing their degradation (PubMed:31255466)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the EXD2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRQNLVALTVTTLLGVAVGGFVLWKGIQRRRRSKTSPVTQQPQQKVLGSRELPPPEDDQLHSSAPRSSWKERILKAKVVTVSQEAEWDQIEPLLRSELEDFPVLGIDCEWVNLEGKASPLSLLQMASPSGLCVLVRLPKLICGGKTLPRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRGCLDLRYLAMRQRNNLLCNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVIYAARDAQISVALFLHLLGYPFSRNSPGEKNDDHSSWRKVLEKCQGVVDIPFRSKGMSRLGEEVNGEATESQQKPRNKKSKMDGMVPGNHQGRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCDRRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYLMVKENLCVVCGKRDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDPERRQVRSGARALLNAESLPTQRKEELLQALREFYNTDVVTEEMLQEAASLETRISNENYVPHGLKVVQCHSQGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNHQKLLRKFGEDLPIQLS", "length": 621, "molWeight": 70353, "crc64": "CD66A3E68A40C7FF", "md5": "B9C1D5543B62377E0C90CF24CBE95444"}}
{"primaryAccession": "Q9NVH2", "text": "This is Integrator complex subunit 7 protein, from Human, contains 962 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NVH2", "organism_name": "Human", "protein_name": "Integrator complex subunit 7", "length": 962, "firstPublicDate": "2006-10-31", "FUNCTION": "Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable), Plays a role in DNA damage response (DDR) signaling during the S phase (PubMed:21659603), May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex (PubMed:23904267)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Integrator subunit 7 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRIFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCECALQTPYDSLKLGMLSVLSTLSGTIAIKHYFSIVPGNVSSSPRSSDLVKLAQECCYHNNRGIAAHGVRVLTNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLAKGRPHLSQSVVETLLTQLHSAQDAARILMCHCLAAIAMQLPVLGDGMLGDLMELYKVIGRSATDKQQELLVSLATVIFVASQKALSVESKAVIKQQLESVSNGWTVYRIARQASRMGNHDMAKELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEENYSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYGDLYQASFDADSATLRNVELQQQSCLLISHAIEALILDPESASFQEYGSTGTAHADSEYERRMMSVYNHVLEEVESLNRKYTPVSYMHTACLCNAIIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRKIQSVCLNVSSTLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFAILGTHNITVESSVKDANGIVWKTGPRTTIFVKSLEDPYSQQIRLQQQQAQQPLQQQQQRNAYTRF", "length": 962, "molWeight": 106834, "crc64": "45253FE31FD5B96D", "md5": "6344BA455B4F69F92E1043A4F34E2EA3"}}
{"primaryAccession": "Q9NVH6", "text": "This is Trimethyllysine dioxygenase, mitochondrial protein, from Human, contains 421 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NVH6", "organism_name": "Human", "protein_name": "Trimethyllysine dioxygenase, mitochondrial", "length": 421, "firstPublicDate": "2002-06-20", "FUNCTION": "Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML) (PubMed:11431483, PubMed:23092983)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the gamma-BBH/TMLD family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MWYHRLSHLHSRLQDLLKGGVIYPALPQPNFKSLLPLAVHWHHTASKSLTCAWQQHEDHFELKYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTIRLDETTLFFTWPDGHVTKYDLNWLVKNSYEGQKQKVIQPRILWNAEIYQQAQVPSVDCQSFLETNEGLKKFLQNFLLYGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDVGECHNHMIGIGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDVVHRWYTAHRTLTIELRRPENEFWVKLKPGRVLFIDNWRVLHGRECFTGYRQLCGCYLTRDDVLNTARLLGLQA", "length": 421, "molWeight": 49518, "crc64": "4E55DF349B866B43", "md5": "3069A1D925FC6A47DFBF6FD31444520E"}}
{"primaryAccession": "Q9NVN8", "text": "This is Guanine nucleotide-binding protein-like 3-like protein protein, from Human, contains 582 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NVN8", "organism_name": "Human", "protein_name": "Guanine nucleotide-binding protein-like 3-like protein", "length": 582, "firstPublicDate": "2007-04-17", "FUNCTION": "Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML, Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation, Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase, Required for cell proliferation, By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition, Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation, By acting on MDM2, may affect TP53 activity, Required for normal processing of ribosomal pre-rRNA, Binds GTP", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TRAFAC class YlqF/YawG GTPase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQALASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD", "length": 582, "molWeight": 65573, "crc64": "B65EE072424F54BC", "md5": "25FBAE2442FFA217C00DD24D8858E842"}}
{"primaryAccession": "Q9NWQ8", "text": "This is Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 protein, from Human, contains 432 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NWQ8", "organism_name": "Human", "protein_name": "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1", "length": 432, "firstPublicDate": "2005-12-20", "FUNCTION": "Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells, Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition, Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins, May be involved in cell adhesion signaling", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESISDLQQGRDITRL", "length": 432, "molWeight": 46981, "crc64": "E86272A0B7E3328C", "md5": "8B93D1FA630876061434D712FFB435A8"}}
{"primaryAccession": "Q9NWS8", "text": "This is Required for meiotic nuclear division protein 1 homolog protein, from Human, contains 449 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NWS8", "organism_name": "Human", "protein_name": "Required for meiotic nuclear division protein 1 homolog", "length": 449, "firstPublicDate": "2006-04-04", "FUNCTION": "Required for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome (PubMed:23022098, PubMed:25604853)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the RMD1/sif2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPATLLRAVARSHHILSKAHQCRRIGHLMLKPLKEFENTTCSTLTIRQSLDLFLPDKTASGLNKSQILEMNQKKSDTSMLSPLNAARCQDEKAHLPTMKSFGTHRRVTHKPNLLGSKWFIKILKRHFSSVSTETFVPKQDFPQVKRPLKASRTRQPSRTNLPVLSVNEDLMHCTAFATADEYHLGNLSQDLASHGYVEVTSLPRDAANILVMGVENSAKEGDPGTIFFFREGAAVFWNVKDKTMKHVMKVLEKHEIQPYEIALVHWENEELNYIKIEGQSKLHRGEIKLNSELDLDDAILEKFAFSNALCLSVKLAIWEASLDKFIESIQSIPEALKAGKKVKLSHEEVMQKIGELFALRHRINLSSDFLITPDFYWDRENLEGLYDKTCQFLSIGRRVKVMNEKLQHCMELTDLMRNHLNEKRALRLEWMIVILITIEVMFELGRVFF", "length": 449, "molWeight": 51604, "crc64": "C4A7B8F6A397B385", "md5": "2354ADA4F23B29AA004189862704D743"}}
{"primaryAccession": "Q9NX18", "text": "This is Succinate dehydrogenase assembly factor 2, mitochondrial protein, from Human, contains 166 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NX18", "organism_name": "Human", "protein_name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "length": 166, "firstPublicDate": "2007-07-10", "FUNCTION": "Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol, Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the SDHAF2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAVSTVFSTSSLMLALSRHSLLSPLLSVTSFRRFYRGDSPTDSQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEHLQHMTEKQLNLYDRLINEPSNDWDIYYWATEAKPAPEIFENEVMALLRDFAKNKNKEQRLRAPDLEYLFEKPR", "length": 166, "molWeight": 19599, "crc64": "AB31FD150E1B6ECA", "md5": "1EDB72AA7530BD315D1BECDFF97FC209"}}
{"primaryAccession": "Q9NX58", "text": "This is Cell growth-regulating nucleolar protein protein, from Human, contains 379 amino acids, has 2 C2HC LYAR-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [1, 26], "description": "C2HC LYAR-type", "keyword_description": "Zinc finger", "textural_description": "C2HC LYAR-type Zinc finger"}, {"location": [28, 52], "description": "C2HC LYAR-type", "keyword_description": "Zinc finger", "textural_description": "C2HC LYAR-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9NX58", "organism_name": "Human", "protein_name": "Cell growth-regulating nucleolar protein", "length": 379, "firstPublicDate": "2005-07-19", "FUNCTION": "Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (PubMed:24495227), Also acts at the level of transcription regulation, Along with PRMT5, binds the gamma-globin (HBG1/HBG2) promoter and represses its expression (PubMed:25092918), In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and SNORD41 that encodes a small nucleolar RNA (PubMed:28686580), Preferentially binds to a DNA motif containing 5'-GGTTAT-3' (PubMed:25092918), Negatively regulates the antiviral innate immune response by targeting IRF3 and impairing its DNA-binding activity (PubMed:31413131), In addition, inhibits NF-kappa-B-mediated expression of pro-inflammatory cytokines (PubMed:31413131), Stimulates phagocytosis of photoreceptor outer segments by retinal pigment epithelial cells (By similarity), Prevents nucleolin/NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2HC LYAR-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVFFTCNACGESVKKIQVEKHVSVCRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEGKTHKGDIKQQAWIQKISELIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSLKVHNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIKAILKQAPDNEITIKKLRKKVLAQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVKLVK", "length": 379, "molWeight": 43634, "crc64": "AF159483CF93ECB6", "md5": "072EE785C66897CF5474996BE7DAFFF7"}}
{"primaryAccession": "Q9NZC9", "text": "This is SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 protein, from Human, contains 954 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NZC9", "organism_name": "Human", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1", "length": 954, "firstPublicDate": "2005-03-01", "FUNCTION": "ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA, Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA), Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA, May play an important role in DNA damage response by acting at stalled replication forks", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SNF2/RAD54 helicase family, SMARCAL1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSLPLTEEQRKKIEENRQKALARRAEKLLAEQHQRTSSGTSIAGNPFQAKQGPSQNFPRESCKPVSHGVIFKQQNLSSSSNADQRPHDSHSFQAKGIWKKPEEMPTACPGHSPRSQMALTGISPPLAQSPPEVPKQQLLSYELGQGHAQASPEIRFTPFANPTHKPLAKPKSSQETPAHSSGQPPRDAKLEAKTAKASPSGQNISYIHSSSESVTPRTEGRLQQKSGSSVQKGVNSQKGKCVRNGDRFQVLIGYNAELIAVFKTLPSKNYDPDTKTWNFSMNDYSALMKAAQSLPTVNLQPLEWAYGSSESPSTSSEGQAGLPSAPSLSFVKGRCMLISRAYFEADISYSQDLIALFKQMDSRRYDVKTRKWSFLLEEHSKLIAKVRCLPQVQLDPLPTTLTLAFASQLKKTSLSLTPDVPEADLSEVDPKLVSNLMPFQRAGVNFAIAKGGRLLLADDMGLGKTIQAICIAAFYRKEWPLLVVVPSSVRFTWEQAFLRWLPSLSPDCINVVVTGKDRLTAGLINIVSFDLLSKLEKQLKTPFKVVIIDESHFLKNSRTARCRAAMPVLKVAKRVILLSGTPAMSRPAELYTQIIAVKPTFFPQFHAFGLRYCDAKRMPWGWDYSGSSNLGELKLLLEEAVMLRRLKSDVLSQLPAKQRKIVVIAPGRINARTRAALDAAAKEMTTKDKTKQQQKDALILFFNRTAEAKIPSVIEYILDLLESGREKFLVFAHHKVVLDAITQELERKHVQHIRIDGSTSSAEREDLCQQFQLSERHAVAVLSITAANMGLTFSSADLVVFAELFWNPGVLIQAEDRVHRIGQTSSVGIHYLVAKGTADDYLWPLIQEKIKVLAEAGLSETNFSEMTESTDYLYKDPKQQKIYDLFQKSFEKEGSDMELLEAAESFDPGSASGTSGSSSQNMGDTLDESSLTASPQKKRRFEFFDNWDSFTSPL", "length": 954, "molWeight": 105938, "crc64": "C5C762C24A2FDD3A", "md5": "5A0776012619DE7CDB9E3C8A983A907E"}}
{"primaryAccession": "Q9NZD4", "text": "This is Alpha-hemoglobin-stabilizing protein protein, from Human, contains 102 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NZD4", "organism_name": "Human", "protein_name": "Alpha-hemoglobin-stabilizing protein", "length": 102, "firstPublicDate": "2002-10-10", "FUNCTION": "Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development, Specifically protects free alpha-hemoglobin from precipitation, It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the AHSP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALLKANKDLISAGLKEFSVLLNQQVFNDPLVSEEDMVTVVEDWMNFYINYYRQQVTGEPQERDKALQELRQELNTLANPFLAKYRDFLKSHELPSHPPPSS", "length": 102, "molWeight": 11840, "crc64": "275DDF8BC670EF20", "md5": "434BAD1342CA60887D362989C60741B4"}}
{"primaryAccession": "Q9NZH8", "text": "This is Interleukin-36 gamma protein, from Human, contains 169 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NZH8", "organism_name": "Human", "protein_name": "Interleukin-36 gamma", "length": 169, "firstPublicDate": "2002-11-08", "FUNCTION": "Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells, Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP, Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation, In cultured keratinocytes induces the expression of macrophage, T-cell, and neutrophil chemokines, such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CL20, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20 and CXCL1; also stimulates its own expression and that of the prototypic cutaneous pro-inflammatory parameters TNF-alpha, S100A7/psoriasin and inducible NOS, May play a role in pro-inflammatory responses during particular neutrophilic airway inflammation: activates mitogen-activated protein kinases and NF-kappa B in primary lung fibroblasts, and stimulates the expression of IL-8 and CXCL3 and Th17 chemokine CCL20 in lung fibroblasts, May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the IL-1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGTPGDADGGGRAVYQSMCKPITGTINDLNQQVWTLQGQNLVAVPRSDSVTPVTVAVITCKYPEALEQGRGDPIYLGIQNPEMCLYCEKVGEQPTLQLKEQKIMDLYGQPEPVKPFLFYRAKTGRTSTLESVAFPDWFIASSKRDQPIILTSELGKSYNTAFELNIND", "length": 169, "molWeight": 18721, "crc64": "F00A9243706F4154", "md5": "84D198ACDCC40B61022DCA6EA24A0321"}}
{"primaryAccession": "Q9NZI6", "text": "This is Transcription factor CP2-like protein 1 protein, from Human, contains 479 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NZI6", "organism_name": "Human", "protein_name": "Transcription factor CP2-like protein 1", "length": 479, "firstPublicDate": "2006-03-21", "FUNCTION": "Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs) (PubMed:25215486, PubMed:26906118), With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity), Required for normal duct development in the salivary gland and kidney (By similarity), Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (By similarity), Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (By similarity), Regulates also the expression of JAG1 and subsequent notch signaling in the collecting duct (By similarity), JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (By similarity), Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (By similarity), Modulates the placental expression of CYP11A1 (PubMed:10644752)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the grh/CP2 family, CP2 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFHDRRLQYTEHQQLEGWRWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAQEKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFGLGEGNASPTHPVEALPVGSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRDDLVQICGPADGIRLFNAIKGRNVRPKMTIYVCQELEQNRVPLQQKRDGSGDSNLSVYHAIFLEELTTLELIEKIANLYSISPQHIHRVYRQGPTGIHVVVSNEMVQNFQDESCFVLSTIKAESNDGYHIILKCGL", "length": 479, "molWeight": 54627, "crc64": "C2D0B56D0705AE75", "md5": "D0C00AD25160D63C8DCCFDE741C8AB88"}}
{"primaryAccession": "Q9NZI7", "text": "This is Upstream-binding protein 1 protein, from Human, contains 540 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NZI7", "organism_name": "Human", "protein_name": "Upstream-binding protein 1", "length": 540, "firstPublicDate": "2006-03-21", "FUNCTION": "Functions as a transcriptional activator in a promoter context-dependent manner, Modulates the placental expression of CYP11A1, Involved in regulation of the alpha-globin gene in erythroid cells, Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity), Involved in regulation of the alpha-globin gene in erythroid cells, Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box, Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the grh/CP2 family, CP2 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDGETEHPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDMPEINGKLVKSIIRVVFHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADYGDSLAKRGSCSPWPDAPTAYVNNSPSPAPTFTSPQQSTCSVPDSNSSSPNHQGDGASQTSGEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLVQICGAADGIRLYNSLKSRSVRPRLTIYVCREQPSSTVLQGQQQAASSASENGSGAPYVYHAIYLEEMIASEVARKLALVFNIPLHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAESSDGIHIILK", "length": 540, "molWeight": 60491, "crc64": "CD95819AA86A7F39", "md5": "1638B2ECA5B569123DC731A7E3DBDC17"}}
{"primaryAccession": "Q9NZP8", "text": "This is Complement C1r subcomponent-like protein protein, from Human, contains 487 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NZP8", "organism_name": "Human", "protein_name": "Complement C1r subcomponent-like protein", "length": 487, "firstPublicDate": "2008-02-26", "FUNCTION": "Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPGPRVWGKYLWRSPHSKGCPGAMWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVFQDFDLEPSQDCAGDSVTISFVGSDPSQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQPSSENKTAHLHKGFLALYQTVAVNYSQPISEASRGSEAINAPGDNPAKVQNHCQEPYYQAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQNQTTLGSSRAKLGNFPWQAFTSIHGRGGGALLGDRWILTAAHTIYPKDSVSLRKNQSVNVFLGHTAIDEMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPLGPNVLPVCLPDNETLYRSGLLGYVSGFGMEMGWLTTELKYSRLPVAPREACNAWLQKRQRPEVFSDNMFCVGDETQRHSVCQGDSGSVYVVWDNHAHHWVATGIVSWGIGCGEGYDFYTKVLSYVDWIKGVMNGKN", "length": 487, "molWeight": 53498, "crc64": "6DE7CE9EA08C7990", "md5": "61C727F4729365A60ECA9D9BC40F1904"}}
{"primaryAccession": "Q9NZS9", "text": "This is Bifunctional apoptosis regulator protein, from Human, contains 450 amino acids, has 1 RING-type Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [34, 74], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9NZS9", "organism_name": "Human", "protein_name": "Bifunctional apoptosis regulator", "length": 450, "firstPublicDate": "2005-12-20", "FUNCTION": "Apoptosis regulator, Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEEPQKSYVNTMDLERDEPLKSTGPQISVSEFSCHCCYDILVNPTTLNCGHSFCRHCLALWWASSKKTECPECREKWEGFPKVSILLRDAIEKLFPDAIRLRFEDIQQNNDIVQSLAAFQKYGNDQIPLAPNTGRANQQMGGGFFSGVLTALTGVAVVLLVYHWSSRESEHDLLVHKAVAKWTAEEVVLWLEQLGPWASLYRERFLSERVNGRLLLTLTEEEFSKTPYTIENSSHRRAILMELERVKALGVKPPQNLWEYKAVNPGRSLFLLYALKSSPRLSLLYLYLFDYTDTFLPFIHTICPLQEDSSGEDIVTKLLDLKEPTWKQWREFLVKYSFLPYQLIAEFAWDWLEVHYWTSRFLIINAMLLSVLELFSFWRIWSRSELKTVPQRMWSHFWKVSTQGLFVAMFWPLIPQFVCNCLFYWALYFNPIINIDLVVKELRRLETQVL", "length": 450, "molWeight": 52738, "crc64": "A662454FC2806CE6", "md5": "B26F5737CADEA9A7A3E8E27376E5B8B5"}}
{"primaryAccession": "Q9P013", "text": "This is Spliceosome-associated protein CWC15 homolog protein, from Human, contains 229 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P013", "organism_name": "Human", "protein_name": "Spliceosome-associated protein CWC15 homolog", "length": 229, "firstPublicDate": "2007-06-26", "FUNCTION": "Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:28076346), Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing, As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CWC15 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKYIK", "length": 229, "molWeight": 26624, "crc64": "B21E6EEF46C4427C", "md5": "009571B00164E8A294F9D4119136582A"}}
{"primaryAccession": "Q9P0G3", "text": "This is Kallikrein-14 protein, from Human, contains 267 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P0G3", "organism_name": "Human", "protein_name": "Kallikrein-14", "length": 267, "firstPublicDate": "2001-01-11", "FUNCTION": "Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity, May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11, May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3, May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface, May be involved in several aspects of tumor progression including growth, invasion and angiogenesis", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Kallikrein subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSLRVLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMRDK", "length": 267, "molWeight": 29122, "crc64": "0CE085DA7BD1D92B", "md5": "C688054866DE8511D575068080E32F2A"}}
{"primaryAccession": "Q9P0M6", "text": "This is Core histone macro-H2A.2 protein, from Human, contains 372 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P0M6", "organism_name": "Human", "protein_name": "Core histone macro-H2A.2", "length": 372, "firstPublicDate": "2001-01-24", "FUNCTION": "Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, May be involved in stable X chromosome inactivation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEILELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGTKGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPGDGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKEFLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIGIYVQEMAKLDAK", "length": 372, "molWeight": 40058, "crc64": "C4B35CD156031AF1", "md5": "4884F9FE2E26026BE0B62231A0846292"}}
{"primaryAccession": "Q9P1Q0", "text": "This is Vacuolar protein sorting-associated protein 54 protein, from Human, contains 977 amino acids, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P1Q0", "organism_name": "Human", "protein_name": "Vacuolar protein sorting-associated protein 54", "length": 977, "firstPublicDate": "2005-05-10", "FUNCTION": "Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN), The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:18367545), Within the GARP complex, required to tether the complex to the TGN, Not involved in endocytic recycling (PubMed:25799061)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the VPS54 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASSHSSSPVPQGSSSDVFFKIEVDPSKHIRPVPSLPDVCPKEPTGDSHSLYVAPSLVTDQHRWTVYHSKVNLPAALNDPRLAKRESDFFTKTWGLDFVDTEVIPSFYLPQISKEHFTVYQQEISQREKIHERCKNICPPKDTFERTLLHTHDKSRTDLEQVPKIFMKPDFALDDSLTFNSVLPWSHFNTAGGKGNRDAASSKLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHELQDYLRKTSQAVKMLRDKIAQIDKVMCEGSLHILRLALTRNNCVKVYNKLKLMATVHQTQPTVQVLLSTSEFVGALDLIATTQEVLQQELQGIHSFRHLGSQLCELEKLIDKMMIAEFSTYSHSDLNRPLEDDCQVLEEERLISLVFGLLKQRKLNFLEIYGEKMVITAKNIIKQCVINKVSQTEEIDTDVVVKLADQMRMLNFPQWFDLLKDIFSKFTIFLQRVKATLNIIHSVVLSVLDKNQRTRELEEISQQKNAAKDNSLDTEVAYLIHEGMFISDAFGEGELTPIAVDTTSQRNASPNSEPCSSDSVSEPECTTDSSSSKEHTSSSAIPGGVDIMVSEDMKLTDSELGKLANNIQELLYSASDICHDRAVKFLMSRAKDGFLEKLNSMEFITLSRLMETFILDTEQICGRKSTSLLGALQSQAIKFVNRFHEERKTKLSLLLDNERWKQADVPAEFQDLVDSLSDGKIALPEKKSGATEERKPAEVLIVEGQQYAVVGTVLLLIRIILEYCQCVDNIPSVTTDMLTRLSDLLKYFNSRSCQLVLGAGALQVVGLKTITTKNLALSSRCLQLIVHYIPVIRAHFEARLPPKQYSMLRHFDHITKDYHDHIAEISAKLVAIMDSLFDKLLSKYEVKAPVPSACFRNICKQMTKMHEAIFDLLPEEQTQMLFLRINASYKLHLKKQLSHLNVINDGGPQNGLVTADVAFYTGNLQALKGLKDLDLNMAEIWEQKR", "length": 977, "molWeight": 110589, "crc64": "3290160E3460C836", "md5": "BCF57FF81B09F76857C8145A7F5D5D14"}}
{"primaryAccession": "Q9P2E8", "text": "This is E3 ubiquitin-protein ligase MARCHF4 protein, from Human, contains 410 amino acids, has 1 RING-CH-type Zinc finger, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [{"location": [155, 215], "description": "RING-CH-type", "keyword_description": "Zinc finger", "textural_description": "RING-CH-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9P2E8", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase MARCHF4", "length": 410, "firstPublicDate": "2005-02-15", "FUNCTION": "E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies, E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {"RING-CH-type Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLMPLCGLLWWWWCCCSGWYCYGLCAPAPQMLRHQGLLKCRCRMLFNDLKVFLLRRPPQAPLPMHGDPQPPGLAANNTLPALGAGGWAGWRGPREVVGREPPPVPPPPPLPPSSVEDDWGGPATEPPASLLSSASSDDFCKEKTEDRYSLGSSLDSGMRTPLCRICFQGPEQGELLSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAISTKNPLQWQAISLTVIEKVQVAAAILGSLFLIASISWLIWSTFSPSARWQRQDLLFQICYGMYGFMDVVCIGLIIHEGPSVYRIFKRWQAVNQQWKVLNYDKTKDLEDQKAGGRTNPRTSSSTQANIPSSEEETAGTPAPEQGPAQAAGHPSGPLSHHHCAYTILHILSHLRPHEQRSPPGSSRELVMRVTTV", "length": 410, "molWeight": 45528, "crc64": "BC812496FCCC2930", "md5": "2D89FD49F05DC553625403B9F45D5FA4"}}
{"primaryAccession": "Q9P2M4", "text": "This is TBC1 domain family member 14 protein, from Human, contains 693 amino acids, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P2M4", "organism_name": "Human", "protein_name": "TBC1 domain family member 14", "length": 693, "firstPublicDate": "2004-06-21", "FUNCTION": "Plays a role in the regulation of starvation-induced autophagosome formation (PubMed:22613832), Together with the TRAPPIII complex, regulates a constitutive trafficking step from peripheral recycling endosomes to the early Golgi, maintaining the cycling pool of ATG9 required for initiation of autophagy", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHSLQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTEREQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDLVVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFARNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH", "length": 693, "molWeight": 78137, "crc64": "6E1332D236DE45BD", "md5": "36CC7975C754526E870EB31AAEC627D8"}}
{"primaryAccession": "Q9P2N6", "text": "This is KAT8 regulatory NSL complex subunit 3 protein, from Human, contains 904 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P2N6", "organism_name": "Human", "protein_name": "KAT8 regulatory NSL complex subunit 3", "length": 904, "firstPublicDate": "2007-05-15", "FUNCTION": "As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAHRGGERDFQTSARRMGTSLLFQLSVHERELDLVFLDHSYAKPWSAHPDASSARPTRMLFVTPRRQHESTIESDVPIDVETVTSTPMPLYDNQKARSVMNECERHVIFARTDADAPPPPEDWEEHVNRTGWTMAQNKLFNKILKALQSDRLARLANEGACNEPVLRRVAVDKCARRVRQALASVSWDTKLIQWLHTTLVETLSLPMLAAYLDALQTLKGKIPTLIDRMLVSSNTKTGAAGAEALSLLLKRPWDPAVGVLSHNKPSKLPGSPLILIASSGPSSSVFPTSRRHRFWQSQLSCLGKVIPVATHLLNNGSGVGVLQCLEHMIGAVRSKVLEIHSHFPHKPIILIGWNTGALVACHVSVMEYVTAVVCLGFPLLTVDGPRGDVDDPLLDMKTPVLFVIGQNSLQCHPEAMEDFREKIRAENSLVVVGGADDNLRISKAKKKSEGLTQSMVDRCIQDEIVDFLTGVLTRAEGHMGSEPRDQDAEKKKKPRDVARRDLAFEVPERGSRPASPAAKLPASPSGSEDLSSVSSSPTSSPKTKVTTVTSAQKSSQIGSSQLLKRHVQRTEAVLTHKQAQAQFAAFLKQNMLVRKALPPGTSSCLFVPISSEPPEEGEKEDLRVQLKRHHPSSPLPGSKTSKRPKIKVSLISQGDTAGGPCAPSQGSAPEAAGGKPITMTLGQASAGAKELTGLLTTAKSSSSEGGVSASPVPSVVSSSTAPSALHTLQSRLVATSPGSSLPGATSASSLLQGLSFSLQDISSKTSGLPANPSPGPAPQATSVKLPTPMQSLGAITTGTSTIVRTIPVATTLSSLGATPGGKPTAIHQLLTNGGLAKLASSLPGLAQISNQASGLKVPTTITLTLRGQPSRITTLSPMGSGAAPSEESSSQVLPSSSQRLPPAP", "length": 904, "molWeight": 95992, "crc64": "698DD46EC443B5DD", "md5": "7D10361D77EFAC0E0FB1FC1BAFBA2E33"}}
{"primaryAccession": "Q9P6M1", "text": "This is Glutathione S-transferase 3 protein, from Fission yeast, contains 242 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P6M1", "organism_name": "Fission yeast", "protein_name": "Glutathione S-transferase 3", "length": 242, "firstPublicDate": "2002-12-06", "FUNCTION": "May have a role in the detoxification of various heavy metals", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the GST superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIVLHHLKNSRSTRIVWMLEELKVPYEIKVYDRVDGRAPPAYTKLSPLGKSPIVVDDGVTYIESAAILEHLVRKYGPSFKPSEEDVAELEKYELWMHFSEASLMPFIWASHVLDLSVNMTPIFFRYIVRQFVNGIKSKYLSKETFLNLDYIDNHLASNEYFAGEQFTAADPQMCFPIFAAQRDYLSQKPYKNIKRWMRVVSDRPACRIAAEKVEDNTLTLFSDVERYSHPPTPPPEQVRSDE", "length": 242, "molWeight": 28113, "crc64": "42324A6B9B672938", "md5": "F643BA1C8A59CAC2785C25DE4924894A"}}
{"primaryAccession": "Q9P6R1", "text": "This is Verprolin protein, from Fission yeast, contains 309 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P6R1", "organism_name": "Fission yeast", "protein_name": "Verprolin", "length": 309, "firstPublicDate": "2009-02-10", "FUNCTION": "Involved in cytoskeletal organization and cellular growth, May exert its effects on the cytoskeleton directly, or indirectly via proline-binding proteins such as profilin or proteins possessing SH3 domains, Plays a role in actin patch assembly by enhancing the ability of myo1 to stimulate actin polymerization by the Arp2/3 complex", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the verprolin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAPAPPPPPPAPAPAAAAPAPPLMTGDRSALLNSIQKGKKLKKATTNDRSAPVVGGGVVGERKSNTPKSFAAPPVPTGAPSLPTSSNNTQQAEERPSMPALGGLFAGGMPKLRHIGKSSASAAPPSAPAPPTPQSELRPPTSAPPRPSIPPPSPASAPPIPSKAPPIPSSLPPPAQPAAPVKSPPSAPSLPSAVPPMPPKVPPPPLSQAPVANTSSRPSSFAPPAGHAPNVTSESPKFPNRGPSIPSASVPPVPPSSYVLQQRPNRVDDHGRFHFKDDSYLPIPHPFLGVPKVYRGGSGTTVPLNLSSF", "length": 309, "molWeight": 31225, "crc64": "47B68086BD93B7D5", "md5": "93A94789E94D1D2CBB6D2F3777D28015"}}
{"primaryAccession": "Q9P7M3", "text": "This is Structure-specific endonuclease subunit slx1 protein, from Fission yeast, contains 271 amino acids, has 1 SLX1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [180, 231], "description": "SLX1-type", "keyword_description": "Zinc finger", "textural_description": "SLX1-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9P7M3", "organism_name": "Fission yeast", "protein_name": "Structure-specific endonuclease subunit slx1", "length": 271, "firstPublicDate": "2008-09-02", "FUNCTION": "Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA, Has a preference for stem-loop (SL) and splayed arm Y structures, Introduces a single-strand cut in duplex DNA on the 3' side of a double-strand/single-strand junction with respect to the single-strand moving 3' to 5' away from the junction, Plays a critical role in maintaining the integrity of the ribosomal DNA (rDNA) loci, where it has a role in re-starting stalled replication forks, The complex initiates homologous recombination (HR) events, used to maintain rDNA copy number, in the rDNA repeats that are processed by a mechanism that requires rad22, but not rhp51, It is also required for suppression of methyl methanesulfonate (MMS) and UV-C irradiation hypersensitivity of the structural maintenance of chromosome (SMC) protein mutant, smc6-74, by overexpression of brc1, Has Holliday junction resolvase activity in vitro", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SLX1 family", "domain_description": {"SLX1-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDLCNFYCCYLLKSNRTQSSGAVYIGSTPDPPRRLRQHNGEIVGGASKTKHGRPWSISCLVYGFPNKVSALKFEWNWQNLGISRYTKDCDFRSKKQKTIMYCLKGLKHLVDSDTWRRWPLNITFLNKTAFSKWNQLGKTYGNINVYFDEEWLNGFHEKVIQKTYDHKLCLRKTISEPVKCNLCYECIESDELRANCPFTDCNSINHLTCLASSFLTEECQVLPIEGMCTKCKRVLRWREFLSTVFTTSLETDERDFESENRIEIIDLELEK", "length": 271, "molWeight": 31701, "crc64": "A7B363ACC0FC7EF9", "md5": "92A4E356CBF19007E9C1D9E5D9608BFF"}}
{"primaryAccession": "Q9PT51", "text": "This is Beta-fibrinogenase brevinase protein, from Mamushi, contains 233 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9PT51", "organism_name": "Mamushi", "protein_name": "Beta-fibrinogenase brevinase", "length": 233, "firstPublicDate": "2007-07-10", "FUNCTION": "Snake venom serine protease that has fibrinogenolytic activities, Preferentially cleaves the Bbeta-chain (FGB) and more slowly the Aa-chain (FGA) of fibrinogen, but does not affect the gamma-chain, Has also fibrinolytic activity, May play a role in antithrombotic reaction as well as thrombolytic reaction", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Snake venom subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "VIGGDECNINEHRFLALLYSERFQCGGTLINEEWVLTAAHCDMGNMYIYLGVHNVSVQYDDEQRRYPKKKYFCLSSRNYNQWDNDIMLIRLNRPVRNSAHIAPLSLPSGPPSVGSVCRVMGWGTITSPNETYPDVPHCANINILDYEVCRAAYAGLPATSRTLCAGILEGGKDSCRGDSGGPLICNGEIQGIVSWGGNICAQPREPGLYTKVFDYIDWIQSIIAGNTTVNCPP", "length": 233, "molWeight": 25725, "crc64": "1676DC5AF0AB5A42", "md5": "3B606E3488F906556B9CD7E740B17884"}}
{"primaryAccession": "Q9PTT2", "text": "This is Jeltraxin protein, from Budgett's frog, contains 225 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9PTT2", "organism_name": "Budgett's frog", "protein_name": "Jeltraxin", "length": 225, "firstPublicDate": "2004-11-09", "FUNCTION": "Calcium-dependent beta-galactose specific lectin", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the pentraxin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKGLVIFFCLFYGCHVAGATGKTIMLFPQKTDTDYVTLKPTERVLNQITVCLKSYTELIKEHSLFSLAMQGSGKDNTLLIYPYPPNNISISIHNEDIYFKVDPEVLQWKRTCVTWDSKTGLLQLWINGKLYPRRITKSRSPIGPQISVILGQEQDSYGGSFDINQAFVGEMSDVNVWDYVLPPENIKAYFSDDYTLDGNFYSWDGGNYTINGLIVVLRNQFIPKL", "length": 225, "molWeight": 25618, "crc64": "68F3CB645AC503EC", "md5": "4D32FC5965C91EB51239C228A2322F1E"}}
{"primaryAccession": "Q9QY02", "text": "This is YTH domain-containing protein 1 protein, from Rat, contains 738 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9QY02", "organism_name": "Rat", "protein_name": "YTH domain-containing protein 1", "length": 738, "firstPublicDate": "2003-02-12", "FUNCTION": "Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs (PubMed:25389274), M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:25389274), Acts as a key regulator of exon-inclusion or exon-skipping during alternative splicing via interaction with mRNA splicing factors SRSF3 and SRSF10 (By similarity), Specifically binds m6A-containing mRNAs and promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing (By similarity), In contrast, interaction with SRSF3 prevents interaction with SRSF10, a splicing factor that promotes exon skipping: this prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing (By similarity), May also regulate alternative splice site selection (PubMed:10564280, PubMed:9473574), Also involved in nuclear export of m6A-containing mRNAs via interaction with SRSF3: interaction with SRSF3 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export (By similarity), Involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts, probably by binding m6A-containing MAT2A mRNAs (By similarity), Also recognizes and binds m6A on other RNA molecules (By similarity), Involved in random X inactivation mediated by Xist RNA: recognizes and binds m6A-containing Xist and promotes transcription repression activity of Xist (By similarity), Also recognizes and binds m6A-containing single-stranded DNA (By similarity), Involved in germline development: required for spermatogonial development in males and oocyte growth and maturation in females, probably via its role in alternative splicing (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSERMESIDTKRQKPSIHSRQLISKPLSSSVSNNKRIVSTKGKSVTEYKNEEYQRSERNKRLDADRKIRLSSSSSREPYKSQPEKPCLRKRDSERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEGNSEEYGSDHETGSSASSEQGNNTENEEEGGEEDVEEDEEVDEDGDDDEEVDEDAEEEEDEEEDEEEEDEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQLIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDYDIHNSRKKPRIDYPPEFHQRPGYLKDPRYQEVDSFTNLIPNRRFSGVRRDVFLNGSYNDYVREFHNMGPPPPWQGMPPYPGIEQPPHHPYYQHHAPPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGRDRERERERICDRDRDRGERGRYRR", "length": 738, "molWeight": 85902, "crc64": "9FC68314E029FA98", "md5": "1CE0EB6D82DF11D16E1F2B221A330D1C"}}
{"primaryAccession": "Q9QY93", "text": "This is dCTP pyrophosphatase 1 protein, from Mouse, contains 170 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9QY93", "organism_name": "Mouse", "protein_name": "dCTP pyrophosphatase 1", "length": 170, "firstPublicDate": "2007-06-26", "FUNCTION": "Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates, Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency, May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSTAGDGERGTVGQEDSAAARPFRFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLALVGEVGELAELFQWKSDTEPGPQAWPPKERAALQEELSDVLIYLVALAARCHVDLPQAVISKMDTNRQRYPVHLSRGSACKYTDLPRGTISENQAVGAGDPASELRDQAST", "length": 170, "molWeight": 18795, "crc64": "A20ECDA7857446A3", "md5": "B7C6E14948ED38FA007796FB63CCF9ED"}}
{"primaryAccession": "Q9QYJ6", "text": "This is cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A protein, from Rat, contains 794 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9QYJ6", "organism_name": "Rat", "protein_name": "cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A", "length": 794, "firstPublicDate": "2008-12-16", "FUNCTION": "Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides, Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the cyclic nucleotide phosphodiesterase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEDGPSNNASCFRRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKAEDEPSPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKADGFALYFLGECNNSLCVFTPPGMKEGQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMHFNLPARICRDIELFHFDIGPFENMWPGIFVYMIHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETAMWISGPATSKSTSEKPTRKVDD", "length": 794, "molWeight": 90161, "crc64": "A36C4678B385846E", "md5": "312FD3CCD35BC2D609227A1B213082E7"}}
{"primaryAccession": "Q9QZQ8", "text": "This is Core histone macro-H2A.1 protein, from Mouse, contains 369 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9QZQ8", "organism_name": "Mouse", "protein_name": "Core histone macro-H2A.1", "length": 369, "firstPublicDate": "2006-03-21", "FUNCTION": "In contrast to isoform 1, does not bind poly-ADP-ribose (By similarity), Represses SOD3 gene expression (PubMed:23022728)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKKQGEVSKAASADSTTEGTPTDGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFYTGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAISAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFMLFDSESIGIYVQEMAKLDAN", "length": 369, "molWeight": 39290, "crc64": "33F123DE5C9C46EC", "md5": "4A9FAEADE31834FDDE31CA253757D32E"}}
{"primaryAccession": "Q9R064", "text": "This is Golgi reassembly-stacking protein 2 protein, from Rat, contains 454 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9R064", "organism_name": "Rat", "protein_name": "Golgi reassembly-stacking protein 2", "length": 454, "firstPublicDate": "2004-08-16", "FUNCTION": "Key structural protein of the Golgi apparatus (By similarity), The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon (By similarity), Acting in concert with GORASP1/GRASP65, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks (By similarity), However, other studies suggest that GORASP2 plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis (PubMed:10487747, PubMed:23940043), May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA (By similarity), Required for normal acrosome formation during spermiogenesis and normal male fertility, probably by promoting colocalization of JAM2 and JAM3 at contact sites between germ cells and Sertoli cells (By similarity), Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane (By similarity)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GORASP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGSSQSVEIPGGGTEGYHVLRVQENSPGHRAGLEPFFDFIVSISGSRLNKDNDTLKDLLKANVEKPVKMLIYSSKTLELREASVTPSNLWGGQGLLGVSIRFCSFDGANENVWHVLEVESNSPAALAGLRPHSDYIIGADTVMNESEDLFSLIETHEAKPLKLYVYNTDTDNCREVIITPNSAWGGEGSLGCGIGYGYLHRIPTRPFEEGKKISLPGQMTGTPITPLKDGFTQVQLSSVSPPSLSPPGTAGVEQSLSGLSISSAPPAVSNVLSTGVPTVPLLPPQVNQSLASVPPMNPAATLPSLMPLSAGLPNLPNLPSLSNFNLPAPHIMPGVGLPELGKPGLPPLPSLPPRNVPGIAPLPMPSDFLPSFPLVPEGSSAASAGEPLSSLPAMGPPSDPVMTTAKADTSSLTVDVMSPASKVPTTVEDRVSDCTPAMEKPVSAVTDANASGAS", "length": 454, "molWeight": 47221, "crc64": "BB6898C85CB6221C", "md5": "253249DD18A0E0DF70138C780F98AA5E"}}
{"primaryAccession": "Q9R0E0", "text": "This is Ceramide glucosyltransferase protein, from Rat, contains 394 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9R0E0", "organism_name": "Rat", "protein_name": "Ceramide glucosyltransferase", "length": 394, "firstPublicDate": "2003-11-07", "FUNCTION": "Participates in the initial step of the glucosylceramide-based glycosphingolipid/GSL synthetic pathway at the cytosolic surface of the Golgi, Catalyzes the transfer of glucose from UDP-glucose to ceramide to produce glucosylceramide/GlcCer (such as beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine) (PubMed:10393098, PubMed:1532799), Glucosylceramide is the core component of glycosphingolipids/GSLs, amphipathic molecules consisting of a ceramide lipid moiety embedded in the outer leaflet of the membrane, linked to one of hundreds of different externally oriented oligosaccharide structures (By similarity), Glycosphingolipids are essential components of membrane microdomains that mediate membrane trafficking and signal transduction (By similarity), They are implicated in many fundamental cellular processes, including growth, differentiation, migration, morphogenesis, cell-to-cell and cell-to-matrix interactions (By similarity), They are required for instance in the proper development and functioning of the nervous system, As an example of their role in signal transduction, they regulate the leptin receptor/LEPR in the leptin-mediated signaling pathway (By similarity), They also play an important role in the establishment of the skin barrier regulating keratinocyte differentiation and the proper assembly of the cornified envelope (By similarity), The biosynthesis of GSLs is also required for the proper intestinal endocytic uptake of nutritional lipids (By similarity), Catalyzes the synthesis of xylosylceramide/XylCer (such as beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine) using UDP-Xyl as xylose donor (By similarity)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the glycosyltransferase 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MALLDLAQEGMALFGFVLFVVLWLMHFMSIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIEVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPAYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTERVGLVHGLPYVADRQGFAATLEQVYFGTSHPRSYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWKFSMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRAGRYRLRCGGTAEEILDV", "length": 394, "molWeight": 44823, "crc64": "214581C0B8D9152C", "md5": "76E5738081D41907E1D82F365AFBB848"}}
{"primaryAccession": "Q9R0J8", "text": "This is Legumain protein, from Rat, contains 435 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9R0J8", "organism_name": "Rat", "protein_name": "Legumain", "length": 435, "firstPublicDate": "2002-07-11", "FUNCTION": "Has a strict specificity for hydrolysis of asparaginyl bonds, Can also cleave aspartyl bonds slowly, especially under acidic conditions, Required for normal lysosomal protein degradation in renal proximal tubules, Required for normal degradation of internalized EGFR, Plays a role in the regulation of cell proliferation via its role in EGFR degradation, May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system (By similarity)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the peptidase C13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTWRVAVLLSLVLGAGAVHIGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANNEENPTPGVVINRPNGTDVYKGVPKDYTGEDVTPENFLAVLRGDEEAVKGKGSGKVLKSGPRDHVFVYFTDHGATGILVFPNEDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDIDVYATTAANPNESSYACYYDEERSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPPVTHLDLTPSPDVPLTILKRKLLRTNNMKESQVLVGQIQHLLDARHIIEKSVQKIVSLLAGFGETAQKHLSERAMLTAHDCHQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEKPYPIDRIKMAMDKVCLSHY", "length": 435, "molWeight": 49466, "crc64": "E835F21C13F17A98", "md5": "5C06C0E9FB64C6403425CBB3F1CA6FA9"}}
{"primaryAccession": "Q9R0U0", "text": "This is Serine/arginine-rich splicing factor 10 protein, from Mouse, contains 262 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9R0U0", "organism_name": "Mouse", "protein_name": "Serine/arginine-rich splicing factor 10", "length": 262, "firstPublicDate": "2004-05-24", "FUNCTION": "Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing, Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70, Required for splicing repression in M-phase cells and after heat shock, Also acts as a splicing factor that specifically promotes exon skipping during alternative splicing, Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing (By similarity), May be involved in regulation of alternative splicing in neurons (PubMed:10583508)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the splicing factor SR family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH", "length": 262, "molWeight": 31301, "crc64": "205F95D36CBBFAB4", "md5": "5F0096D4A985FB5DE7F3386A6262F9B5"}}
{"primaryAccession": "Q9R2C1", "text": "This is Stress-associated endoplasmic reticulum protein 1 protein, from Rat, contains 66 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9R2C1", "organism_name": "Rat", "protein_name": "Stress-associated endoplasmic reticulum protein 1", "length": 66, "firstPublicDate": "2007-02-06", "FUNCTION": "Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum, Protects unfolded target proteins against degradation during ER stress, May facilitate glycosylation of target proteins after termination of ER stress, May modulate the use of N-glycosylation sites on target proteins", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the RAMP4 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPEEKASVGPWLLALFIFVVCGSAIFQIIQSIRMGM", "length": 66, "molWeight": 7374, "crc64": "DC15C0143AAE0D91", "md5": "2F86ADF66712AEA3501C7B47CF06A82E"}}
{"primaryAccession": "Q9S757", "text": "This is Bifunctional L-3-cyanoalanine synthase/cysteine synthase C1, mitochondrial protein, from Mouse-ear cress, contains 368 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9S757", "organism_name": "Mouse-ear cress", "protein_name": "Bifunctional L-3-cyanoalanine synthase/cysteine synthase C1, mitochondrial", "length": 368, "firstPublicDate": "2012-09-05", "FUNCTION": "Acts as a major beta-cyanoalanine synthase, The cyanoalanine synthesis reaction is more efficient than the cysteine synthase activity, Probably unable to interact with SAT and to form the decameric Cys synthase complex (CSC) and is therefore not an enzymatically true OASTL protein, Probably involved in the detoxification of cyanide that arises from ethylene biosynthesis, Maintains a low level of cyanide for proper root hair development", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the cysteine synthase/cystathionine beta-synthase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASVSRRLLRRETIPCFSHTVRKLFSTVGSPSFAQRLRDLPKDFPSTNAKRDASLLIGKTPLVFLNKVTEGCEAYVAAKQEHFQPTCSIKDRPAIAMIADAEKKKLIIPGKTTLIEPTSGNMGISLAFMAAMKGYRIIMTMPSYTSLERRVTMRSFGAELVLTDPAKGMGGTVKKAYDLLDSTPDAFMCQQFANPANTQIHFDTTGPEIWEDTLGNVDIFVMGIGSGGTVSGVGRYLKSKNPNVKIYGVEPAESNILNGGKPGPHAITGNGVGFKPEILDMDVMESVLEVSSEDAIKMARELALKEGLMVGISSGANTVAAIRLAKMPENKGKLIVTIHASFGERYLSSVLFDELRKEAEEMKPVSVD", "length": 368, "molWeight": 39927, "crc64": "CFDE474F4E404184", "md5": "78DA377B52A388514C923710B69D2C96"}}
{"primaryAccession": "Q9S7H8", "text": "This is Isochorismate synthase 1, chloroplastic protein, from Mouse-ear cress, contains 569 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9S7H8", "organism_name": "Mouse-ear cress", "protein_name": "Isochorismate synthase 1, chloroplastic", "length": 569, "firstPublicDate": "2002-03-05", "FUNCTION": "Isochorismate synthase involved in the synthesis of salicylic acid (SA) required for both local and systemic acquired resistance (LAR and SAR) while SA synthesized through the phenylalanine ammonium lyase (PAL) pathway seems to potentiate plant cell death, Also involved in phylloquinone (vitamin K1) synthesis, Has no isochorismate pyruvate lyase (IPL) activity", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the isochorismate synthase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASLQFSSQFLGSNTKTHSSIISISRSYSPTPFTRFSRKKYESCSMSMNGCDGDFKTPLGTVETRTMTAVLSPAAATERLISAVSELKSQPPSFSSGVVRLQVPIDQQIGAIDWLQAQNEIQPRCFFSRRSDVGRPDLLLDLANENGNGNGNGTVSSDRNLVSVAGIGSAVFFRDLDPFSHDDWRSIRRFLSSTSPLIRAYGGMRFDPNGKIAVEWEPFGAFYFSVPQVEFNEFGGSSMLAATIAWDDELSWTLENAIEALQETMLQVSSVVMKLRNRSLGVSVLSKNHVPTKGAYFPAVEKALEMINQKSSPLNKVVLARNSRIITDTDIDPIAWLAQLQREGHDAYQFCLQPPGAPAFIGNTPERLFQRTQLGVCSEALAATRPRAASSARDMEIERDLLTSPKDDLEFSIVRENIREKLNGICDRVVVKPQKTVRKLARVQHLYSQLAGRLTKEDDEYKILAALHPTPAVCGLPAEEARLLIKEIESFDRGMYAGPIGFFGGEESEFAVGIRSALVEKGLGALIYAGTGIVAGSDPSSEWNELDLKISQFTKSIEYEATTSLQAIN", "length": 569, "molWeight": 62575, "crc64": "E60963196FBBB81C", "md5": "AE69FA9032F318C5DBC87ADB51B9F425"}}
{"primaryAccession": "Q9S834", "text": "This is ATP-dependent Clp protease proteolytic subunit 5, chloroplastic protein, from Mouse-ear cress, contains 298 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9S834", "organism_name": "Mouse-ear cress", "protein_name": "ATP-dependent Clp protease proteolytic subunit 5, chloroplastic", "length": 298, "firstPublicDate": "2007-11-13", "FUNCTION": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis, Has a chymotrypsin-like activity, Plays a major role in the degradation of misfolded proteins (By similarity)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the peptidase S14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAHACVSTSASSLRFTAGFVSASPNGSSFDSPKLSLPFEPLRSRKTNKLVSDRKNWKNSTPKAVYSGNLWTPEIPSPQGVWSIRDDLQVPSSPYFPAYAQGQGPPPMVQERFQSIISQLFQYRIIRCGGAVDDDMANIIVAQLLYLDAVDPTKDIVMYVNSPGGSVTAGMAIFDTMRHIRPDVSTVCVGLAASMGAFLLSAGTKGKRYSLPNSRIMIHQPLGGAQGGQTDIDIQANEMLHHKANLNGYLAYHTGQSLEKINQDTDRDFFMSAKEAKEYGLIDGVIMNPLKALQPLAAA", "length": 298, "molWeight": 32356, "crc64": "0B550019A2F6A33C", "md5": "27DC0514B02DA4AE93804F1FF092FD05"}}
{"primaryAccession": "Q9S841", "text": "This is Oxygen-evolving enhancer protein 1-2, chloroplastic protein, from Mouse-ear cress, contains 331 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9S841", "organism_name": "Mouse-ear cress", "protein_name": "Oxygen-evolving enhancer protein 1-2, chloroplastic", "length": 331, "firstPublicDate": "2000-12-01", "FUNCTION": "Stabilizes the manganese cluster which is the primary site of water splitting, Regulates dephosphorylation and turnover of the PSII reaction center D1 protein", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the PsbO family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATSLQAAATFLQPAKIAASPSRNVHLRSNQTVGKSFGLDSSQARLTCSLHSDLKDFAGKCSDAAKIAGFALATSALVVSGAGAEGAPKRLTYDEIQSKTYMEVKGTGTANQCPTIDGGSETFSFKAGKYTGKKFCFEPTSFTVKADSVSKNAPPDFQNTKLMTRLTYTLDEIEGPFEVGSDGSVKFKEEDGIDYAAVTVQLPGGERVPFLFTVKQLEASGKPESFSGKFLVPSYRGSSFLDPKGRGGSTGYDNAVALPAGGRGDEEELSKENVKNTAASVGEITLKITKSKPETGEVIGVFESLQPSDTDLGAKVPKDVKIQGVWYGQIE", "length": 331, "molWeight": 35019, "crc64": "08F837E651B1C2E7", "md5": "40F9D2D689A5CBA344AFD6FFDE5B2BC2"}}
{"primaryAccession": "Q9S850", "text": "This is Sulfite oxidase protein, from Mouse-ear cress, contains 393 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9S850", "organism_name": "Mouse-ear cress", "protein_name": "Sulfite oxidase", "length": 393, "firstPublicDate": "2005-04-26", "FUNCTION": "Probably involved in sulfite oxidative detoxification", "SUBCELLULAR LOCATION": "Peroxisome", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPGIRGPSEYSQEPPRHPSLKVNAKEPFNAEPPRSALVSSYVTPVDLFYKRNHGPIPIVDHLQSYSVTLTGLIQNPRKLFIKDIRSLPKYNVTATLQCAGNRRTAMSKVRNVRGVGWDVSAIGNAVWGGAKLADVLELVGIPKLTASTNLGARHVEFVSVDRCKEENGGPYKASITLSQATNPEADVLLAYEMNGETLNRDHGFPLRVVVPGVIGARSVKWLDSINVIAEESQGFFMQKDYKMFPPSVNWDNINWSSRRPQMDFPVQSAICSVEDVQMVKPGKVSIKGYAVSGGGRGIERVDISLDGGKNWVEASRTQEPGKQYISEHSSSDKWAWVLFEATIDVSQTTEVIAKAVDSAANVQPENVESVWNLRGVLNTSWHRVLLRLGHSNL", "length": 393, "molWeight": 43329, "crc64": "00B4AC49E92C5DD2", "md5": "AF85B417CDCFC31851A76873A60B25B3"}}
{"primaryAccession": "Q9SA96", "text": "This is Arogenate dehydratase/prephenate dehydratase 1, chloroplastic protein, from Mouse-ear cress, contains 392 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SA96", "organism_name": "Mouse-ear cress", "protein_name": "Arogenate dehydratase/prephenate dehydratase 1, chloroplastic", "length": 392, "firstPublicDate": "2009-05-05", "FUNCTION": "Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine (PubMed:17726025), Dehydratase that uses arogenate and prephenate as substrates (PubMed:17726025), Utilzes more efficiently arogenate than prephenate (PubMed:17726025)", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALRCFPIWVCPQTTHHRSPLMGLAEFDADKRRRFCLWECSSSASQRAVTAIEGEIPFSRELKKSSDELGLTQETQSLSFHRDLSMLPKPLTANSLYSSDGDDSKVRISFQGIPGAYSETAALKAFPNCETVPCEQFEAAFQAVELWLVDKAVLPIENSVGGSIHRNYDLLLRHRLHIVQEVHLPVNHCLLGVPGVKKEDIKCVLSHPQALDQCVNSLNNLGIQRISAKDTATAAQTVSSSGKIDVGAIASVRAANIYGLDILAENIQDDVNNVTRFLILAREPMIPRTDRPYKTSIVFSLEEGPGVLFKALAVFALRSINLSKIESRPQRRRPLRVVDGSNNGSAKYFDYLFYIDFEASMADTRAQHALGHLQEFASFIRILGCYPMDLVR", "length": 392, "molWeight": 43605, "crc64": "1B1468660C420BCE", "md5": "DFAD87193174E93504AF3A174B5B42B9"}}
{"primaryAccession": "Q9SAA2", "text": "This is ATP-dependent Clp protease proteolytic subunit 6, chloroplastic protein, from Mouse-ear cress, contains 271 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SAA2", "organism_name": "Mouse-ear cress", "protein_name": "ATP-dependent Clp protease proteolytic subunit 6, chloroplastic", "length": 271, "firstPublicDate": "2007-11-13", "FUNCTION": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis, Has a chymotrypsin-like activity, Plays a major role in the degradation of misfolded proteins (By similarity), Essential protein required for chloroplast development and integrity", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the peptidase S14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAGLAISPPLGLSFSSRTRNPKPTSFLSHNQRNPIRRIVSALQSPYGDSLKAGLSSNVSGSPIKIDNKAPRFGVIEAKKGNPPVMPSVMTPGGPLDLSSVLFRNRIIFIGQPINAQVAQRVISQLVTLASIDDKSDILMYLNCPGGSTYSVLAIYDCMSWIKPKVGTVAFGVAASQGALLLAGGEKGMRYAMPNTRVMIHQPQTGCGGHVEDVRRQVNEAIEARQKIDRMYAAFTGQPLEKVQQYTERDRFLSASEALEFGLIDGLLETEY", "length": 271, "molWeight": 29382, "crc64": "5565ADB698D0C776", "md5": "E35D0D54D5D209033484E31AFC0FF009"}}
{"primaryAccession": "Q9SAK4", "text": "This is Succinate-semialdehyde dehydrogenase, mitochondrial protein, from Mouse-ear cress, contains 528 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SAK4", "organism_name": "Mouse-ear cress", "protein_name": "Succinate-semialdehyde dehydrogenase, mitochondrial", "length": 528, "firstPublicDate": "2006-10-31", "FUNCTION": "Oxidizes specifically succinate semialdehyde, Involved in plant response to environmental stress by preventing the accumulation of reactive oxygen species, probably by regulating proline, gamma-hydroxybutyrate (GHB) and gamma-aminobutyrate (GABA) levels (PubMed:15642352), Required for the maintenance of the shoot apical meristem (SAM) structure and subsequent adaxial-abaxial axis-dependent development of cotyledons and leaves (PubMed:21690177, PubMed:25840087)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the aldehyde dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVIGAAARVAIGGCRKLISSHTSLLLVSSQCRQMSMDAQSVSEKLRSSGLLRTQGLIGGKWLDSYDNKTIKVNNPATGEIIADVACMGTKETNDAIASSYEAFTSWSRLTAGERSKVLRRWYDLLIAHKEELGQLITLEQGKPLKEAIGEVAYGASFIEYYAEEAKRVYGDIIPPNLSDRRLLVLKQPVGVVGAITPWNFPLAMITRKVGPALASGCTVVVKPSELTPLTALAAAELALQAGVPPGALNVVMGNAPEIGDALLTSPQVRKITFTGSTAVGKKLMAAAAPTVKKVSLELGGNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKFAEAFSEAVQKLEVGDGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGGKRHSLGMTFYEPTVIRDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIAGLAAYIFTNSVQRSWRVFEALEYGLVGVNEGLISTEVAPFGGVKQSGLGREGSKYGMDEYLEIKYVCLGDMNRH", "length": 528, "molWeight": 56559, "crc64": "A0DA95A3A592B5B9", "md5": "64A861E2CC971997C0066CD426E2D600"}}
{"primaryAccession": "Q9SAK5", "text": "This is Myb family transcription factor APL protein, from Mouse-ear cress, contains 358 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SAK5", "organism_name": "Mouse-ear cress", "protein_name": "Myb family transcription factor APL", "length": 358, "firstPublicDate": "2009-03-24", "FUNCTION": "Transcription factor required for phloem identity, Has a dual role both in promoting phloem differentiation and in repressing xylem differentiation during vascular development, Regulates the expression of the transcription factor NAC045 (AC A4VCM0), May activate the transcription of specific genes involved in phosphate uptake or assimilation (PubMed:15592750), Promotes flowering through transcriptional activation of both FT and its transport machinery component, FTIP1 (PubMed:26239308)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MYB-CC family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFHAKKPSSMNGSYENRAMCVQGDSGLVLTTDPKPRLRWTVELHERFVDAVAQLGGPDKATPKTIMRVMGVKGLTLYHLKSHLQKFRLGKQPHKEYGDHSTKEGSRASAMDIQRNVASSSGMMSRNMNEMQMEVQRRLHEQLEVQRHLQLRIEAQGKYMQSILERACQTLAGENMAAATAAAAVGGGYKGNLGSSSLSAAVGPPPHPLSFPPFQDLNIYGNTTDQVLDHHNFHHQNIENHFTGNNAADTNIYLGKKRPNPNFGNDVRKGLLMWSDQDHDLSANQSIDDEHRIQIQMATHVSTDLDSLSEIYERKSGLSGDEGNNGGKLLERPSPRRSPLSPMMNPNGGLIQGRNSPFG", "length": 358, "molWeight": 39598, "crc64": "F92EABC974F8BF9F", "md5": "11D822C432E5B66D98A45C3E8B23C182"}}
{"primaryAccession": "Q9SB31", "text": "This is AT-hook motif nuclear-localized protein 3 protein, from Mouse-ear cress, contains 404 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SB31", "organism_name": "Mouse-ear cress", "protein_name": "AT-hook motif nuclear-localized protein 3", "length": 404, "firstPublicDate": "2015-03-04", "FUNCTION": "Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity), Acts redundantly with AHL4 to regulate the formation of tissue boundary between the xylem and procambium in the root meristem (PubMed:23335615)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEEREGTNINNNITSSFGLKQQHEAAASDGGYSMDPPPRPENPNPFLVPPTTVPAAATVAAAVTENAATPFSLTMPTENTSAEQLKKKRGRPRKYNPDGTLVVTLSPMPISSSVPLTSEFPPRKRGRGRGKSNRWLKKSQMFQFDRSPVDTNLAGVGTADFVGANFTPHVLIVNAGEDVTMKIMTFSQQGSRAICILSANGPISNVTLRQSMTSGGTLTYEGRFEILSLTGSFMQNDSGGTRSRAGGMSVCLAGPDGRVFGGGLAGLFLAAGPVQVMVGTFIAGQEQSQLELAKERRLRFGAQPSSISFNISAEERKARFERLNKSVAIPAPTTSYTHVNTTNAVHSYYTNSVNHVKDPFSSIPVGGGGGGEVGEEEGEEDDDELEGEDEEFGGDSQSDNEIPS", "length": 404, "molWeight": 43014, "crc64": "FD0E81CDA7740F01", "md5": "73B780D2E0CBD3CF871E039220C77E0A"}}
{"primaryAccession": "Q9SB60", "text": "This is Adenylate isopentenyltransferase 4 protein, from Mouse-ear cress, contains 318 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SB60", "organism_name": "Mouse-ear cress", "protein_name": "Adenylate isopentenyltransferase 4", "length": 318, "firstPublicDate": "2010-02-09", "FUNCTION": "Involved in cytokinin biosynthesis, Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP, but not to AMP, Has no DMAPP:tRNA isopentenyltransferase activity", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the IPP transferase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKCNDKMVVIMGATGSGKSSLSVDLALHFKAEIINSDKMQFYDGLKITTNQSTIEDRRGVPHHLLGELNPEAGEVTAAEFRVMAAEAISEITQRKKLPILAGGSNSYIHALLAKSYDPENYPFSDHKGSICSELKYDCCFIWIDVDQSVLFEYLSLRLDLMMKSGMFEEIAEFHRSKKAPKEPLGIWKAIGVQEFDDYLKMYKWDNDMDKWDPMRKEAYEKAVRAIKENTFQLTKDQITKINKLRNAGWDIKKVDATASFREAIRAAKEGEGVAEMQRKIWNKEVLEPCVKIVRSHLDQPINYYYYYFYLLKRFLSLN", "length": 318, "molWeight": 36674, "crc64": "BE8BD9FF52E20F08", "md5": "3E247F22994E30910D1116B1CA2AEF82"}}
{"primaryAccession": "Q9SCR2", "text": "This is Cyclin-dependent kinase inhibitor 2 protein, from Mouse-ear cress, contains 209 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SCR2", "organism_name": "Mouse-ear cress", "protein_name": "Cyclin-dependent kinase inhibitor 2", "length": 209, "firstPublicDate": "2007-07-10", "FUNCTION": "Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity, Regulates cell division which is crucial for plant growth, development and morphogenesis, May regulate early lateral root initiation by blocking the G1/S phase transition, Controls the mitosis-to-endocycle transition and the onset of the endoreduplication cycle during leaf development through inhibition of mitotic CDKA-1 kinase complexes, Specifically targets CDKA-1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CDI family, ICK/KRP subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAVRRRERDVVEENGVTTTTVKRRKMEEEVDLVESRIILSPCVQATNRGGIVARNSAGASETSVVIVRRRDSPPVEEQCQIEEEDSSVSCCSTSEEKSKRRIEFVDLEENNGDDRETETSWIYDDLNKSEESMNMDSSSVAVEDVESRRRLRKSLHETVKEAELEDFFQVAEKDLRNKLLECSMKYNFDFEKDEPLGGGRYEWVKLNP", "length": 209, "molWeight": 24037, "crc64": "0E5EEFE9ED256B53", "md5": "FA6DF3F1BA3BFE11F308CFE45F7D43FC"}}
{"primaryAccession": "Q9SCY2", "text": "This is Peptidyl-prolyl cis-trans isomerase FKBP13, chloroplastic protein, from Mouse-ear cress, contains 208 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SCY2", "organism_name": "Mouse-ear cress", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP13, chloroplastic", "length": 208, "firstPublicDate": "2002-06-20", "FUNCTION": "PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides, Responsive of the major PPIase activity in the chloroplast thylakoid lumen, Regulates the accumulation of Rieske protein, an essential component of the photosynthetic electron transport chain", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the FKBP-type PPIase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSLGFSVGTCSPPSEKRKCRFLVNNSLNKAEAINLRNKQKVSSDPELSFAQLSSCGRREAIIGFGFSIGLLDNVSALAETTSCEFSVSPSGLAFCDKVVGYGPEAVKGQLIKAHYVGKLENGKVFDSSYNRGKPLTFRIGVGEVIKGWDQGILGSDGIPPMLTGGKRTLRIPPELAYGDRGAGCKGGSCLIPPASVLLFDIEYIGKA", "length": 208, "molWeight": 22039, "crc64": "4E6640FE7955A48F", "md5": "284AAED2789BFCC0BF7ED8FF35F5A233"}}
{"primaryAccession": "Q9SCY3", "text": "This is Photosynthetic NDH subunit of lumenal location 4, chloroplastic protein, from Mouse-ear cress, contains 217 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SCY3", "organism_name": "Mouse-ear cress", "protein_name": "Photosynthetic NDH subunit of lumenal location 4, chloroplastic", "length": 217, "firstPublicDate": "2006-02-07", "FUNCTION": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain, The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone, Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (Probable), PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity), Seems to be essential for stabilizing the NDH subcomplex A (PubMed:19903870)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the FKBP-type PPIase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAISTLTLTQSLYTRSFRPTIFFSSSSSSSFSCLCSSSSDCEPKLSVKKRVFGVGLGFLASSILSLTPLDADATRIDYYATVGDPLCEYSYAKSGLGFCDLDVGFGDEAPRGVLVNIHYTARFADGTLFDSSYKRARPLTMRIGVGKVIRGLDQGILGGEGVPPMRVGGKRKLQIPPKLAYGPEPAGCFSGDCNIPGNATLLYDINFVEIYPGSNTR", "length": 217, "molWeight": 23260, "crc64": "1122EE1BAFD20E19", "md5": "776D3916EA438C0AA9FBCD70E279F365"}}
{"primaryAccession": "Q9SDW0", "text": "This is Trihelix transcription factor GT-3a protein, from Mouse-ear cress, contains 323 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SDW0", "organism_name": "Mouse-ear cress", "protein_name": "Trihelix transcription factor GT-3a", "length": 323, "firstPublicDate": "2010-11-30", "FUNCTION": "Probable transcription factor that binds specifically to the core DNA sequence 5'-GTTAC-3'", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDRRNPFQHHHHHHQLHHHLIQQQQLPPPPLSTTATMDPGGGGGGGERIPQWSIEETKELLAIREELDQTFMETKRNKLLWEVVAAKMADKGFVRSAEQCKSKWKNLVTRYKACETTEPDAIRQQFPFYNEIQSIFEARMQRMLWSEATEPSTSSKRKHHQFSSDDEEEEVDEPNQDINEELLSLVETQKRETEVITTSTSTNPRKRAKKGKGVASGTKAETAGNTLKDILEEFMRQTVKMEKEWRDAWEMKEIEREKREKEWRRRMAELEEERAATERRWMEREEERRLREEARAQKRDSLIDALLNRLNRDHNDDHHNQGF", "length": 323, "molWeight": 38273, "crc64": "7A359042B5B6E10C", "md5": "71001BE660347A33017DE8A26D7E63FF"}}
{"primaryAccession": "Q9SEL7", "text": "This is Protease Do-like 5, chloroplastic protein, from Mouse-ear cress, contains 323 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SEL7", "organism_name": "Mouse-ear cress", "protein_name": "Protease Do-like 5, chloroplastic", "length": 323, "firstPublicDate": "2001-08-14", "FUNCTION": "Probable serine protease", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the peptidase S1C family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTMALASSKAFSSIFNTLSPINQSKFVLACSGSNHVDVIDRRRRIMIFGSSLALTSSLLGSNQQRLPMESAIALEQFKEKEEELEEEEERNVNLFQKTSPSVVYIEAIELPKTSSGDILTDEENGKIEGTGSGFVWDKLGHIVTNYHVIAKLATDQFGLQRCKVSLVDAKGTRFSKEGKIVGLDPDNDLAVLKIETEGRELNPVVLGTSNDLRVGQSCFAIGNPYGYENTLTIGVVSGLGREIPSPNGKSISEAIQTDADINSGNSGGPLLDSYGHTIGVNTATFTRKGSGMSSGVNFAIPIDTVVRTVPYLIVYGTAYRDRF", "length": 323, "molWeight": 34923, "crc64": "D1F929C721E53422", "md5": "02149CCBE66E3730C61A72969439C668"}}
{"primaryAccession": "Q9SEX2", "text": "This is Katanin p60 ATPase-containing subunit A1 protein, from Mouse-ear cress, contains 523 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SEX2", "organism_name": "Mouse-ear cress", "protein_name": "Katanin p60 ATPase-containing subunit A1", "length": 523, "firstPublicDate": "2005-03-01", "FUNCTION": "Severs microtubules in vitro in an ATP-dependent manner, Required for oligomerization of functional KTN80-KTN1 complexes that catalyze microtubule severing (PubMed:28978669), This activity may promote rapid reorganization of cellular microtubule arrays, May be required for reorientation of cortical microtubule arrays during cellular elongation, Failure to correctly orient these arrays drastically compromises fiber length, cell wall thickness and mechanical strength, May also be required for the spatial organization of developmental cues within the root", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the AAA ATPase family, Katanin p60 subunit A1 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVGSSNSLAGLQDHLKLAREYALEGSYDTSVIFFDGAIAQINKHLNTLDDPLARTKWMNVKKAIMEETEVVKQLDAERRAFKEAPTGRRAASPPINTKSSFVFQPLDEYPTSSGGGPMDDPDVWRPPTRDVTSRRPARAGQTGTRKSPQDGAWARGPTTRTGPASRGGRGGATSKSTAGARSSTAGKKGAASKSNKAESMNGDAEDGKSKRGLYEGPDEDLAAMLERDVLDSTPGVRWDDVAGLSEAKRLLEEAVVLPLWMPEYFQGIRRPWKGVLMFGPPGTGKTLLAKAVATECGTTFFNVSSATLASKWRGESERMVRCLFDLARAYAPSTIFIDEIDSLCNSRGGSGEHESSRRVKSELLVQVDGVSNTATNEDGSRKIVMVLAATNFPWDIDEALRRRLEKRIYIPLPDFESRKALININLRTVEVASDVNIEDVARRTEGYSGDDLTNVCRDASMNGMRRKIAGKTRDEIKNMSKDDISNDPVAMCDFEEAIRKVQPSVSSSDIEKHEKWLSEFGSA", "length": 523, "molWeight": 57236, "crc64": "2AE8813109DC972B", "md5": "D1C03C702B2C3BF91D7739460E71B19C"}}
{"primaryAccession": "Q9SGS2", "text": "This is High mobility group B protein 9 protein, from Mouse-ear cress, contains 338 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SGS2", "organism_name": "Mouse-ear cress", "protein_name": "High mobility group B protein 9", "length": 338, "firstPublicDate": "2010-11-02", "FUNCTION": "Binds preferentially DNA with A/T-rich content (PubMed:19053246), Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus (PubMed:16698901)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSDNESTPSQATVEMMATSPAKIKEYPEPLALHEVVVKDSSVFWDTLRRFHSIMSTKFMIPVIGGKELDLHVLYVEVTRRGGYEKVVVEKKWREVGGVFRFSATTTSASFVLRKHYLNLLFHYEQVHLFTARGPLLHPIATFHANPSTSKEMALVEYTPPSIRYHNTHPPSQGSSSFTAIGTIEGKFDCGYLVKVKLGSEILNGVLYHSAQPGPSSSPTAVLNNAVVPYVETGRRRRRLGKRRRSRRREDPNYPKPNRSGYNFFFAEKHCKLKSLYPNKEREFTKLIGESWSNLSTEERMVYQDIGLKDKERYQRELNEYRETLRLRDGDMTNGKAF", "length": 338, "molWeight": 38774, "crc64": "EA54C0EC7AD39070", "md5": "84B3D1626A38BB82023DC25586578A27"}}
{"primaryAccession": "Q9SHJ5", "text": "This is Glycerol-3-phosphate acyltransferase 1 protein, from Mouse-ear cress, contains 585 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SHJ5", "organism_name": "Mouse-ear cress", "protein_name": "Glycerol-3-phosphate acyltransferase 1", "length": 585, "firstPublicDate": "2005-05-10", "FUNCTION": "Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis, Involved in pollen development, by being required for tapetum differentiation and male fertility, In addition to the sporophytic effect, it also exerts a gametophytic effect on pollen performance", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the GPAT/DAPAT family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVLPELLVILAEWVLYRLLAKSCYRAARKLRGYGFQLKNLLSLSKTQSLHNNSQHHLHNHHQQNHPNQTLQDSLDPLFPSLTKYQELLLDKNRACSVSSDHYRDTFFCDIDGVLLRQHSSKHFHTFFPYFMLVAFEGGSIIRAILLLLSCSFLWTLQQETKLRVLSFITFSGLRVKDMDNVSRSVLPKFFLENLNIQVYDIWARTEYSKVVFTSLPQVLVERFLREHLNADDVIGTKLQEIKVMGRKFYTGLASGSGFVLKHKSAEDYFFDSKKKPALGIGSSSSPQDHIFISICKEAYFWNEEESMSKNNALPRERYPKPLIFHDGRLAFLPTPLATLAMFIWLPIGFLLAVFRISVGVFLPYHVANFLASMSGVRITFKTHNLNNGRPEKGNSGVLYVCNHRTLLDPVFLTTSLGKPLTAVTYSLSKFSEFIAPLKTVSLKRDRKKDGEAMQRLLSKGDLVVCPEGTTCREPYLLRFSPLFAELTEDIVPVAVDARVSMFYGTTASGLKCLDPIFFLMNPRPVYCLEILKKLPKEMTCAGGKSSFEVANFIQGELARVLGFECTNLTRRDKYLVLAGNEGIVR", "length": 585, "molWeight": 66514, "crc64": "3F7FDCE161C28EAF", "md5": "8F3469C250019EFAD1605C235C012A67"}}
{"primaryAccession": "Q9SIC4", "text": "This is Endonuclease III homolog 1, chloroplastic protein, from Mouse-ear cress, contains 379 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SIC4", "organism_name": "Mouse-ear cress", "protein_name": "Endonuclease III homolog 1, chloroplastic", "length": 379, "firstPublicDate": "2014-04-16", "FUNCTION": "Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage, The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site, The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, Primarily recognizes and repairs oxidative base damage of pyrimidines", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the Nth/MutY family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MILLVNGGAATSIHPNAARFYRIGTMSRQIHGAVSSSKHISLKTQHPLSDSNSELAYGASGSETRVYTRKKRLKQEPFEPLEKYSGKGVNTHKLCGLPDIEDFAYKKTIGSPSSSRSTETSITVTSVKTAGYPPENWVEVLEGIRQMRSSEDAPVDSMGCDKAGSFLPPTERRFAVLLGALLSSQTKDQVNNAAIHRLHQNGLLTPEAVDKADESTIKELIYPVGFYTRKATYMKKIARICLVKYDGDIPSSLDDLLSLPGIGPKMAHLILHIAWNDVQGICVDTHVHRICNRLGWVSRPGTKQKTTSPEETRVALQQWLPKEEWVAINPLLVGFGQMICTPIRPRCEACSVSKLCPAAFKETSSPSSKLKKSNRSKEP", "length": 379, "molWeight": 41728, "crc64": "18EF0C9D4DE70A9A", "md5": "66825C6FF68FFF442588639AB34681F9"}}
{"primaryAccession": "Q9SID1", "text": "This is B-box zinc finger protein 25 protein, from Mouse-ear cress, contains 238 amino acids, has 1 B box-type 1; atypical Zinc finger, has 1 B box-type 2; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [5, 47], "description": "B box-type 1; atypical", "keyword_description": "Zinc finger", "textural_description": "B box-type 1; atypical Zinc finger"}, {"location": [57, 99], "description": "B box-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "B box-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9SID1", "organism_name": "Mouse-ear cress", "protein_name": "B-box zinc finger protein 25", "length": 238, "firstPublicDate": "2001-12-05", "FUNCTION": "Acts as negative regulator of seedling photomorphogenesis (PubMed:18540109), BBX25/STH and BBX24/STO function as transcriptional corepressors of HY5 activity, leading to the down-regulation of BBX22 expression, BBX25/STH acts additively with BBX24/STO during de-etiolation and the hypocotyl shade avoidance response (PubMed:23624715)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"B box-type 1; atypical Zinc finger": 1, "B box-type 2; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKIQCDVCEKAPATLICCADEAALCAKCDVEVHAANKLASKHQRLFLDSLSTKFPPCDICLEKAAFIFCVEDRALLCRDCDEATHAPNTRSANHQRFLATGIRVALSSTSCNQEVEKNHFDPSNQQSLSKPPTQQPAAPSPLWATDEFFSYSDLDCSNKEKEQLDLGELDWLAEMGLFGDQPDQEALPVAEVPELSFSHLAHAHSYNRPMKSNVPNKKQRLEYRYDDEEEHFLVPDLG", "length": 238, "molWeight": 26657, "crc64": "1088617F55A003AF", "md5": "558B49004417B17DC7F55D5CCA126C83"}}
{"primaryAccession": "Q9SIM9", "text": "This is F-box protein MAX2 protein, from Mouse-ear cress, contains 693 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SIM9", "organism_name": "Mouse-ear cress", "protein_name": "F-box protein MAX2", "length": 693, "firstPublicDate": "2007-01-23", "FUNCTION": "Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins, Promotes the senescence, Is necessary for responses to strigolactones and karrikins, Contributes to the selective repression of axillary shoots and moderates the branching by regulating negatively the auxin transport in primary stems, in an AXR1-independent manner (PubMed:11487692, PubMed:11874909, PubMed:15737939, PubMed:16546078, PubMed:22357928, PubMed:9351240), Required for the progression of leaf senescence mediated by methyl jasmonate (PubMed:26507893), Required at each node to suppress axillary bud growth (PubMed:17346265)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASTTLSDLPDVILSTISSLVSDSRARNSLSLVSHKFLALERSTRSHLTIRGNARDLSLVPDCFRSISHLDLSFLSPWGHTLLASLPIDHQNLLALRLKFCFPFVESLNVYTRSPSSLELLLPQWPRIRHIKLLRWHQRASQIPTGGDFVPIFEHCGGFLESLDLSNFYHWTEDLPPVLLRYADVAARLTRLDLLTASFTEGYKSSEIVSITKSCPNLKTFRVACTFDPRYFEFVGDETLSAVATSSPKLTLLHMVDTASLANPRAIPGTEAGDSAVTAGTLIEVFSGLPNLEELVLDVGKDVKHSGVALEALNSKCKKLRVLKLGQFQGVCSATEWRRLDGVALCGGLQSLSIKNSGDLTDMGLVAIGRGCCKLTTFEIQGCENVTVDGLRTMVSLRSKTLTDVRISCCKNLDTAASLKAIEPICDRIKRLHIDCVWSGSEDEEVEGRVETSEADHEEEDDGYERSQKRCKYSFEEEHCSTSDVNGFCSEDRVWEKLEYLSLWINVGEFLTPLPMTGLDDCPNLEEIRIKIEGDCRGKRRPAEPEFGLSCLALYPKLSKMQLDCGDTIGFALTAPPMQMDLSLWERFFLTGIGSLSLSELDYWPPQDRDVNQRSLSLPGAGLLQECLTLRKLFIHGTAHEHFMNFLLRIPNLRDVQLRADYYPAPENDMSTEMRVGSCSRFEDQLNSRNIID", "length": 693, "molWeight": 77415, "crc64": "F25B70B219F48CC6", "md5": "03F0E82142D780B54D29C8ABE8A3F8B8"}}
{"primaryAccession": "Q9SIW2", "text": "This is Protein CHROMATIN REMODELING 35 protein, from Mouse-ear cress, contains 888 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SIW2", "organism_name": "Mouse-ear cress", "protein_name": "Protein CHROMATIN REMODELING 35", "length": 888, "firstPublicDate": "2015-09-16", "FUNCTION": "Subunit of the chromatin-remodeling complex (DDR complex) that mediates RNA polymerases IV and V (Pol IV and Pol V) recruitment to chromatin (PubMed:19013275, PubMed:22864289), Cooperates with Pol IV and Pol V to regulates RNA- and RNAi- (RNA interference) directed non-CpG de novo DNA methylation on cytosine of genes targeted for silencing and enhancers, also known as siRNA-directed DNA methylation (RdDM), thus leading to epigenetic modification of the genome and promoting/maintaining heterochromatin (PubMed:15120073, PubMed:15947783, PubMed:15924141, PubMed:16724114, PubMed:16741558, PubMed:19204117, PubMed:19825647, PubMed:22647529, PubMed:18425128), In collaboration with Pol V, mediates/maintains, in cis, methylation-associated self-silencing of exogenous transgene transcribing inverted-repeat (exo-IR) silencer (exo-Pdsi) to restrain exo-IR dsRNA accumulation and subsequent inappropriate silencing of active protein-coding genes (e,g, PDS) by exo-IR-derivating 24-nt siRNAs (PubMed:21771120), Also required to mediate loss of CpG methylation when the silencing inducer is withdrawn (PubMed:15947783), Required for the maintenance of retrotransposon large terminal repeats (LTRs) and transposable elements (TE) edges silencing mediated by cytosine methylation (PubMed:16724114, PubMed:23540698), Required for transcriptional repression of specific classes of pericentromeric 180-bp repeats by promoting condensation and histone H3 lysine 9 dimethylation (H3K9me2) at chromocenters (PubMed:19825650), Required for basal resistance against the necrotrophic fungal pathogen Plectosphaerella cucumerina (PubMed:22242006)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the helicase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGFVYIVMTGYYKNVHKRKQNQVDDGPEAKRVKSSAKVIDYSNPFAVSNMLEALDSGKFGSVSKELEEIADMRMDLVKRSIWLYPSLAYTVFEAEKTMDNQQVVEGVINLDDDDDDDTDVEKKALCVVPSSSEIVLLDSDDEDNERQRPMYQFQSTLVQHQKNQGDVTPLIPQCSFEEVDLGRGKEMPSAIKAIVEGQTSRGKVLPIENGVVNEKGVYVGVEEDDSDNESEAADEDLGNIWNEMALSIECSKDVARETSHKEKADVVEDCEHSFILKDDMGYVCRVCGVIEKSILEIIDVQFTKAKRNTRTYASETRTKRFGESDNELKFSEEGLMIGGLAAHPTHAAEMKPHQIEGFQFLCSNLVADDPGGCIMAHAPGSGKTFMIISFMQSFLAKYPQAKPLVVLPKGILPTWKKEFVRWQVEDIPLLDFYSAKAENRAQQLSILKQWMEKKSILFLGYQQFSTIVCDDTTDSLSCQEILLKVPSILILDEGHTPRNEDTNLLQSLAQVQTPRKVVLSGTLYQNHVKEVFNILNLVRPKFLKLDTSKSAVKRILAYTPCDVRGRLTGSNSDMASMFNETVEHTLQKSEDFTVKIKVIQDLREMTKKVLHYYKGDFLDELPGLADFTVVLNLSPKQLNEVKKLRREKRKFKVSAVGSAIYLHPKLKVFSDKSDDVSDTTMDEMVEKLDLNEGVKAKFFLNLINLCDSAGEKLLVFSQYLIPLKFLERLAALAKGWKLGKEVFVLTGNTSSEQREWSMETFNSSPDAKIFFGSIKACGEGISLVGASRILILDVPLNPSVTRQAIGRAFRPGQKKMVHAYRLIAGSSPEEEDHNTCFKKEVISKMWFEWNEYCGYQNFEVETIDVDEAGDTFLESPALREDIRVLYKR", "length": 888, "molWeight": 100229, "crc64": "D304DE3D5E593430", "md5": "371B9DA97BEAB36115D2EC7E75077CC6"}}
{"primaryAccession": "Q9SJU5", "text": "This is B-box zinc finger protein 18 protein, from Mouse-ear cress, contains 172 amino acids, has 1 B box-type 1; atypical Zinc finger, has 1 B box-type 2; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [5, 47], "description": "B box-type 1; atypical", "keyword_description": "Zinc finger", "textural_description": "B box-type 1; atypical Zinc finger"}, {"location": [56, 96], "description": "B box-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "B box-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9SJU5", "organism_name": "Mouse-ear cress", "protein_name": "B-box zinc finger protein 18", "length": 172, "firstPublicDate": "2014-10-29", "FUNCTION": "Acts as negative regulator of seedling photomorphogenesis (PubMed:18540109), Acts as a negative regulator of blue light-mediated inhibition of hypocotyl elongation through increase of bioactive gibberellin levels (PubMed:20872270), Acts as a repressor of thermotolerance by modulating expression of a set of heat shock-responsive genes (PubMed:23238922)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"B box-type 1; atypical Zinc finger": 1, "B box-type 2; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRILCDACESAAAIVFCAADEAALCCSCDEKVHKCNKLASRHLRVGLADPSNAPSCDICENAPAFFYCEIDGSSLCLQCDMVVHVGGKRTHRRFLLLRQRIEFPGDKPNHADQLGLRCQKASSGRGQESNGNGDHDHNMIDLNSNPQRVHEPGSHNQEEGIDVNNANNHEHE", "length": 172, "molWeight": 18891, "crc64": "90774B714E352633", "md5": "F798295D27EC3DA5D3E9EE085F1A201F"}}
{"primaryAccession": "Q9SJW3", "text": "This is Protein SPIRAL1 protein, from Mouse-ear cress, contains 119 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SJW3", "organism_name": "Mouse-ear cress", "protein_name": "Protein SPIRAL1", "length": 119, "firstPublicDate": "2012-06-13", "FUNCTION": "Required for directional control of cell elongation, Stabilizes growing ends of cortical microtubules and influences their dynamic properties, Acts redundantly with SP1Ls in maintaining the cortical microtubules organization essential for anisotropic cell growth, Plays a key role in salt stress-induced microtubules disassembly", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the SPIRAL1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGRGNSCGGGQSSLDYLFGGDAPAPKPVPAPRPAPTESNNGPAPPVTAVTATALTTATTSVEPAELNKQIPAGIKTPVNNYARAEGQNTGNFLTDRPSTKVHAAPGGGSSLDYLFTGGK", "length": 119, "molWeight": 11920, "crc64": "5D2281B17D942FD6", "md5": "6879553B4FE9F5E23289625F5EF587C0"}}
{"primaryAccession": "Q9SKX1", "text": "This is Transcription factor IBH1 protein, from Mouse-ear cress, contains 156 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SKX1", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor IBH1", "length": 156, "firstPublicDate": "2014-05-14", "FUNCTION": "Atypical and probable non DNA-binding bHLH transcription factor that acts as transcriptional repressor that negatively regulates cell and organ elongation in response to gibberellin (GA) and brassinosteroid (BR) signaling, Is able to form heterodimer with BHLH49, thus inhibiting DNA binding of BHLH49, which is a transcriptional activator that regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif, Binds and inhibits HBI1, a positive regulator of cell elongation that directly binds to the promoters and activated the two expansin genes EXPA1 and EXPA8, encoding cell wall loosening enzymes, The ability of IBH1 to inhibit BHLH49 and HBI1 is counteracted by binding to the antagonist bHLH transcription factor PRE1, restoring the transcriptional activity of BHLH49 and HBI1 and resulting in induction of cell elongation, Functions redundantly with IBL1/BHLH159 in a regulation node known as the incoherent feed-forward loop (FFL) (PubMed:24505057)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bHLH protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASADKLINTDVPEKDVFAFHFLQSLSNLRKQNPFDTPDQKNYRVRKIKKAAYVSMARAAGGSSRLWSRALLRRADKDDNKIVRFSRRKWKISSKRRRSNQRAPVVEEAAERLRNLVPGGGGMETSKLMEETAHYIKCLSMQVKVMQCLVDGLSPK", "length": 156, "molWeight": 17825, "crc64": "7D8C75BE4047A48A", "md5": "C87806A2105021A99E9C19EF64EFF65C"}}
{"primaryAccession": "Q9SKX5", "text": "This is Polyamine oxidase 2 protein, from Mouse-ear cress, contains 490 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SKX5", "organism_name": "Mouse-ear cress", "protein_name": "Polyamine oxidase 2", "length": 490, "firstPublicDate": "2008-10-14", "FUNCTION": "Flavoenzyme involved in polyamine back-conversion (PubMed:20532512, PubMed:21081665), Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine, spermidine and their acetyl derivatives (PubMed:20532512, PubMed:21081665), Substrate preference is N(1)-acetylspermine > spermine > spermidine (PubMed:21081665), Plays an important role in the regulation of polyamine intracellular concentration (Probable), Involved in abscisic acid-mediated developmental processes (PubMed:26310141), May contribute to nitric oxide-mediated effects on root growth (PubMed:26310141)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the flavin monoamine oxidase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MESRKNSDRQMRRANCFSAGERMKTRSPSVIVIGGGFGGISAARTLQDASFQVMVLESRDRIGGRVHTDYSFGFPVDLGASWLHGVCKENPLAPVIGRLGLPLYRTSGDNSVLYDHDLESYALFDMDGNQVPQELVTQIGVTFERILEEINKVRDEQDADISISQAFSIVFSRKPELRLEGLAHNVLQWYVCRMEGWFAADAETISAKCWDQEELLPGGHGLMVRGYRPVINTLAKGLDIRVGHRVTKIVRRYNGVKVTTENGQTFVADAAVIAVPLGVLKSGTIKFEPKLPEWKQEAINDLGVGIENKIILHFEKVFWPKVEFLGVVAETSYGCSYFLNLHKATGHPVLVYMPAGQLAKDIEKMSDEAAANFAVLQLQRILPDALPPVQYLVSRWGSDVNSMGSYSYDIVGKPHDLYERLRVPVDNLFFAGEATSSSFPGSVHGAYSTGLMAAEDCRMRVLERYGELDLFQPVMGEEGPASVPLLISRL", "length": 490, "molWeight": 54321, "crc64": "48E8EBD38AEC1E8E", "md5": "93F3986262178D3A9FACDE57ABAB61EB"}}
{"primaryAccession": "Q9SMR2", "text": "This is Tubulin-folding cofactor C protein, from Mouse-ear cress, contains 345 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SMR2", "organism_name": "Mouse-ear cress", "protein_name": "Tubulin-folding cofactor C", "length": 345, "firstPublicDate": "2012-11-28", "FUNCTION": "Essential tubulin-folding protein involved in the final step of the tubulin folding pathway, Required for continuous microtubule cytoskeleton organization, mitotic division, cytokinesis, and to couple cell cycle progression to cell division in embryos and endosperms, Not essential for cell viability, Binds probably to the multimeric supercomplex, stimulating GTP hydrolysis by the bound beta-tubulin and the release of the alpha-/beta-tubulin heterodimer", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TBCC family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEDDGQSSVAETLDPALQKKHHDMLERLSARHQARKSDSPDSSSSSSSTLESTSSFLAKFSDSKRSIESRIAESRLASSSTDSSKLKSDLAEISVAIDNLEKLLAENSYFLPSYEVRSSLKIVSDLKQSLDILSGELVPKKKFSFKSKSTTKKPESKLPEIQKPDVVLPPKLVPVRDSPGLRNKHGETLVKSFEGSSIGEFTLSDLDSCQVKLTGTVNALFLHRLKKCSVYTGPVIGSILIDDVEDCVLVLASHQIRIHCARKSDFYLRVRSRPIIEDSNGVRFAPYCLDYKGIDEDLKTAGLEEETNNWANVDDFRWLRAVQSPNWSLLPEEERVSLLTISGDS", "length": 345, "molWeight": 38309, "crc64": "74C9A612473FF295", "md5": "74E065B3E9DD84CAB42C12E3A7DB4234"}}
{"primaryAccession": "Q9SMX3", "text": "This is Mitochondrial outer membrane protein porin 3 protein, from Mouse-ear cress, contains 274 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SMX3", "organism_name": "Mouse-ear cress", "protein_name": "Mitochondrial outer membrane protein porin 3", "length": 274, "firstPublicDate": "2002-11-15", "FUNCTION": "Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules, The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the eukaryotic mitochondrial porin (TC 1,B,8,1) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVKGPGLYTEIGKKARDLLYRDYQGDQKFSVTTYSSTGVAITTTGTNKGSLFLGDVATQVKNNNFTADVKVSTDSSLLTTLTFDEPAPGLKVIVQAKLPDHKSGKAEVQYFHDYAGISTSVGFTATPIVNFSGVVGTNGLSLGTDVAYNTESGNFKHFNAGFNFTKDDLTASLILNDKGEKLNASYYQIVSPSTVVGAEISHNFTTKENAITVGTQHALDPLTTVKARVNNAGVANALIQHEWRPKSFFTVSGEVDSKAIDKSAKVGIALALKP", "length": 274, "molWeight": 29211, "crc64": "938E671BEB454275", "md5": "D352F65D4868A15669995A1A3C82AA61"}}
{"primaryAccession": "Q9SNC3", "text": "This is Fasciclin-like arabinogalactan protein 4 protein, from Mouse-ear cress, contains 420 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SNC3", "organism_name": "Mouse-ear cress", "protein_name": "Fasciclin-like arabinogalactan protein 4", "length": 420, "firstPublicDate": "2006-10-03", "FUNCTION": "May be a cell surface adhesion protein that is required for normal cell expansion", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the fasciclin-like AGP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MANVISISHFTLLALPYLLLLLSSTAAAINVTAVLSSFPNLSSFSNLLVSSGIAAELSGRNSLTLLAVPNSQFSSASLDLTRRLPPSALADLLRFHVLLQFLSDSDLRRIPPSGSAVTTLYEASGRTFFGSGSVNVTRDPASGSVTIGSPATKNVTVLKLLETKPPNITVLTVDSLIVPTGIDITASETLTPPPTSTSLSPPPAGINLTQILINGHNFNVALSLLVASGVITEFENDERGAGITVFVPTDSAFSDLPSNVNLQSLPAEQKAFVLKFHVLHSYYTLGSLESITNPVQPTLATEEMGAGSYTLNISRVNGSIVTINSGVVLAVVTQTAFDQNPVSVFGVSKVLLPKELFPKSGQPVATAPPQEISLSPESSSEQPSRLVSPPREIVSSGAVKRPLGFLVLWCWCIAFCYVLV", "length": 420, "molWeight": 44239, "crc64": "449C626DA86A3A57", "md5": "ABAA30119F51C364308585C2BB275273"}}
{"primaryAccession": "Q9SPG2", "text": "This is Transcription factor MYB28 protein, from Mouse-ear cress, contains 366 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SPG2", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor MYB28", "length": 366, "firstPublicDate": "2012-02-22", "FUNCTION": "Major regulator of short-chained aliphatic glucosinolates (GLSs) biosynthesis, Together with MYB29/HAG3 and MYB76/HAG2, promotes aliphatic glucosinolate biosynthesis but represses indolic glucosinolate biosynthesis, Prevents insect performance (e,g, lepidopteran insect Mamestra brassicae and Spodoptera exigua) by promoting glucosinolates", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRKPCCVGEGLKKGAWTTEEDKKLISYIHDHGEGGWRDIPQKAGLKRCGKSCRLRWTNYLKPEIKRGEFSSEEEQIIIMLHASRGNKWSVIARHLPRRTDNEIKNYWNTHLKKRLMEQGIDPVTHKPLASSSNPTVDENLNSPNASSSDKQYSRSSSMPFLSRPPPSSCNMVSKVSELSSNDGTPIQGSSLSCKKRFKKSSSTSRLLNKVAAKATSIKDILSASMEGSLSATTISHASFFNGFTEQIRNEEDSSNTSLTNTLAEFDPFSPSSLYPEHEINATSDLNMDQDYDFSQFFEKFGGDNHNEENSMNDLLMSDVSQEVSSTSVDDQDNMVGNFEGWSNYLLDHTNFMYDTDSDSLEKHFI", "length": 366, "molWeight": 41134, "crc64": "DD7533DCB1857D0B", "md5": "129F7EE0482B927D5D1FCC55333B9EC0"}}
{"primaryAccession": "Q9SPG9", "text": "This is Transcription factor MYB24 protein, from Mouse-ear cress, contains 214 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SPG9", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor MYB24", "length": 214, "firstPublicDate": "2013-12-11", "FUNCTION": "Transcription factor acting redundantly with MYB21 and MYB57 to control stamen filament elongation in the late developed flowers, Contributes with MYB21 to induction of MYB108 by jasmonate, Repressed at the transcript levels by DELLA proteins", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEKRESSGGSGSGDAEVRKGPWTMEEDLILINYIANHGEGVWNSLAKSAGLKRTGKSCRLRWLNYLRPDVRRGNITPEEQLTIMELHAKWGNRWSKIAKHLPGRTDNEIKNFWRTKIQKYIIKSGETTTVGSQSSEFINHHATTSHVMNDTQETMDMYSPTTSYQHASNINQQLNYGNYVPESGSIMMPLSVDQSEQNYWSVDDLWPMNIYNGN", "length": 214, "molWeight": 24459, "crc64": "B5DAE2471F75673F", "md5": "DC044BAF4D9E5149F3B936EB51DC6E1D"}}
{"primaryAccession": "Q9SPM5", "text": "This is Apyrase 2 protein, from Mouse-ear cress, contains 472 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SPM5", "organism_name": "Mouse-ear cress", "protein_name": "Apyrase 2", "length": 472, "firstPublicDate": "2012-10-31", "FUNCTION": "Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates, Substrate preference is ATP > ADP, Functions with APY1 to reduce extracellular ATP level which is essential for pollen germination and normal plant development, Plays a role in the regulation of stomatal function by modulating extracellular ATP levels in guard cells", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GDA1/CD39 NTPase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTAKRGIGRHESLADKIQRHRGIILVISVPIVLIGLVLLLMPGRSISDSVVEEYSVHNRKGGPNSRGPKNYAVIFDAGSSGSRVHVYCFDQNLDLIPLGNELELFLQLKPGLSAYPTDPRQAANSLVSLLDKAEASVPRELRPKTHVRVGATAGLRTLGHDASENILQAVRELLRDRSMLKTEANAVTVLDGTQEGSYQWVTINYLLRNLGKPYSDTVGVVDLGGGSVQMAYAISEEDAASAPKPLEGEDSYVREMYLKGRKYFLYVHSYLHYGLLAARAEILKVSEDSENPCIVAGYDGMYKYGGKEFKAPASQSGASLDECRRITINALKVNDTLCTHMKCTFGGVWNGGRGGGQKNMFVASFFFDRAAEAGFVDPKQPVATVRPMDFEKAAKKACSMKLEEGKSTFPLVEEENLPYLCMDLVYQYTLLIDGFGLEPSQTITLVKKVKYGDQAVEAAWPLGSAIEAVSSP", "length": 472, "molWeight": 51599, "crc64": "FA0C280456D51224", "md5": "ED8901B390E1C4ABFDBB44225EFFDE62"}}
{"primaryAccession": "Q9SQG2", "text": "This is Apyrase 1 protein, from Mouse-ear cress, contains 471 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SQG2", "organism_name": "Mouse-ear cress", "protein_name": "Apyrase 1", "length": 471, "firstPublicDate": "2012-10-31", "FUNCTION": "Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates, Substrate preference is ATP > ADP, Functions with APY2 to reduce extracellular ATP level which is essential for pollen germination and normal plant development, Plays a role in the regulation of stomatal function by modulating extracellular ATP levels in guard cells", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GDA1/CD39 NTPase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTAKRAIGRHESLADKVHRHRGLLLVISIPIVLIALVLLLMPGTSTSVSVIEYTMKNHEGGSNSRGPKNYAVIFDAGSSGSRVHVYCFDQNLDLVPLENELELFLQLKPGLSAYPNDPRQSANSLVTLLDKAEASVPRELRPKTPVRVGATAGLRALGHQASENILQAVRELLKGRSRLKTEANAVTVLDGTQEGSYQWVTINYLLRTLGKPYSDTVGVVDLGGGSVQMAYAIPEEDAATAPKPVEGEDSYVREMYLKGRKYFLYVHSYLHYGLLAARAEILKVSEDSNNPCIATGYAGTYKYGGKAFKAAASPSGASLDECRRVAINALKVNNSLCTHMKCTFGGVWNGGGGGGQKKMFVASFFFDRAAEAGFVDPNQPVAEVRPLDFEKAANKACNMRMEEGKSKFPRVEEDNLPYLCLDLVYQYTLLVDGFGLKPSQTITLVKKVKYGDYAVEAAWPLGSAIEAVSSP", "length": 471, "molWeight": 51194, "crc64": "6EF17A73207ECDA2", "md5": "92FAE2ABC2A4AA73D9C029FD998138BF"}}
{"primaryAccession": "Q9SRH5", "text": "This is Mitochondrial outer membrane protein porin 1 protein, from Mouse-ear cress, contains 276 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SRH5", "organism_name": "Mouse-ear cress", "protein_name": "Mitochondrial outer membrane protein porin 1", "length": 276, "firstPublicDate": "2002-05-02", "FUNCTION": "Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules, The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity), Involved in plant development at reproductive stage, is important for pollen development and may regulate hydrogen peroxide generation during disease resistance", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the eukaryotic mitochondrial porin (TC 1,B,8,1) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVKGPGLYTEIGKKARDLLYKDHNSDQKFSITTFSPAGVAITSTGTKKGDLLLGDVAFQSRRKNITTDLKVCTDSTFLITATVDEAAPGLRSIFSFKVPDQNSGKVELQYLHEYAGISTSMGLTQNPTVNFSGVIGSNVLAVGTDVSFDTKSGNFTKINAGLSFTKEDLIASLTVNDKGDLLNASYYHIVNPLFNTAVGAEVSHKLSSKDSTITVGTQHSLDPLTSVKARVNSAGIASALIQHEWKPKSFFTISGEVDTKSIDKSAKVGLALALKP", "length": 276, "molWeight": 29425, "crc64": "7F33F53E56E9765C", "md5": "E7A47C52D5BD922EE10F96AD7AFAF30F"}}
{"primaryAccession": "Q9SSA5", "text": "This is Peptidyl-prolyl cis-trans isomerase CYP38, chloroplastic protein, from Mouse-ear cress, contains 437 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SSA5", "organism_name": "Mouse-ear cress", "protein_name": "Peptidyl-prolyl cis-trans isomerase CYP38, chloroplastic", "length": 437, "firstPublicDate": "2008-07-01", "FUNCTION": "Required for the assembly and stabilization of PSII, but has no PPIases activity", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAAFASLPTFSVVNSSRFPRRRIGFSCSKKPLEVRCSSGNTRYTKQRGAFTSLKECAISLALSVGLMVSVPSIALPPNAHAVANPVIPDVSVLISGPPIKDPEALLRYALPIDNKAIREVQKPLEDITDSLKIAGVKALDSVERNVRQASRTLQQGKSIIVAGFAESKKDHGNEMIEKLEAGMQDMLKIVEDRKRDAVAPKQKEILKYVGGIEEDMVDGFPYEVPEEYRNMPLLKGRASVDMKVKIKDNPNIEDCVFRIVLDGYNAPVTAGNFVDLVERHFYDGMEIQRSDGFVVQTGDPEGPAEGFIDPSTEKTRTVPLEIMVTGEKTPFYGSTLEELGLYKAQVVIPFNAFGTMAMAREEFENDSGSSQVFWLLKESELTPSNSNILDGRYAVFGYVTDNEDFLADLKVGDVIESIQVVSGLENLANPSYKIAG", "length": 437, "molWeight": 47982, "crc64": "7239C7ADE83953E0", "md5": "4CF1059EE765189044134AA76219A0E9"}}
{"primaryAccession": "Q9SSD1", "text": "This is Protein TOO MANY MOUTHS protein, from Mouse-ear cress, contains 496 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SSD1", "organism_name": "Mouse-ear cress", "protein_name": "Protein TOO MANY MOUTHS", "length": 496, "firstPublicDate": "2002-08-02", "FUNCTION": "Promotes cell fate progression in stomatal development, In leaves, needed to correctly orient spacing divisions, to limit the number of asymmetric divisions in neighbor cells, and to promote the asymmetric (amplifying) divisions of meristemoids, In stems, promotes the conversion of meristemoids into guard mother cells (GMC) (PubMed:11090210, PubMed:12040198, PubMed:18979118), Positively regulates CAPRICE (CPC) expression in differentiating stomaless-forming cell files (PubMed:19513241), Forms constitutive complexes with ERECTA and ERL1 involved in the recognition of the stomatal regulatory peptides EPF1, EPF2 and EPFL9/STOMAGEN (PubMed:28536146), Modulates the activity of the ligand-receptor pairs EPF2-ERECTA and EPF1-ERL1 in stomatal development (PubMed:16002616, PubMed:22241782), Functions in a combinatorial specific manner with the ERECTA-family (ERf) receptor kinases in the regulation of the immune response (PubMed:27446127)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the RLP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MARYEFFRQIFIVLSIVSPLVRSFTVITSDSTAPSALIDGPQTGFTMTNDGARTEPDEQDAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDPQRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDNSLTGPVPFERDTVWRMRRKLRLYNNAGLCVNRDSDLDDAFGSKSGSTVRLCDAETSRPAPSGTVQHLSREEDGALPDGATDVSSTSKSLGFSYLSAFFLVFPNFIFMLISS", "length": 496, "molWeight": 54505, "crc64": "BC4A7958FD3153F2", "md5": "216D43DA095812EE5E369157BFA25A6F"}}
{"primaryAccession": "Q9SSE7", "text": "This is Arogenate dehydratase/prephenate dehydratase 2, chloroplastic protein, from Mouse-ear cress, contains 381 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SSE7", "organism_name": "Mouse-ear cress", "protein_name": "Arogenate dehydratase/prephenate dehydratase 2, chloroplastic", "length": 381, "firstPublicDate": "2009-05-05", "FUNCTION": "Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine (PubMed:17726025), Dehydratase that uses arogenate and prephenate as substrates (PubMed:17726025), Utilzes more efficiently arogenate than prephenate (PubMed:17726025), Required for chloroplast division prior to ARC5, but in an ARC3- and ARC6-dependent manner, especially involved in the Z-ring formation (PubMed:30252596)", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAMHTVRLSPATQLHGGISSNLSPPNRKPNNSIVRYGCGSSKRFRIVTVLASLRENDANGRDNSVRAMEVKKIFEDSPLLPKPLSSNQLTESVSNGSRVRVAYQGVRGAYSESAAEKAYPNCEAVPCEEFDTAFEAVERWLVDRAVLPIENSLGGSIHRNYDLLLRHNLHIVGEVKLAVRHCLLANHGVNIEDLRRVLSHPQALAQCENTLTKLGLVREAVDDTAGAAKQIAFENLNDAAAVASEKAAKIYGLNIVAKDIQDDCDNVTRFLMLAREPIIPGTNRLFKTSIVFSLEEGPGVLFKALAVFALRQINLTKIESRPLRKHPLRASGGLKYFDYLFYVDFEASMADEVAQNALRHLEEFATFLRVLGSYPVDTTML", "length": 381, "molWeight": 42115, "crc64": "04AC7EB3988B0AF7", "md5": "EF66E82588F13FF721231DB16867DF5E"}}
{"primaryAccession": "Q9SSS9", "text": "This is ATP synthase subunit delta, chloroplastic protein, from Mouse-ear cress, contains 234 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SSS9", "organism_name": "Mouse-ear cress", "protein_name": "ATP synthase subunit delta, chloroplastic", "length": 234, "firstPublicDate": "2015-03-04", "FUNCTION": "This protein is part of the stalk that links CF(0) to CF(1), It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the ATPase delta chain family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASLQQTLFSLQSKLPPSSFQIARSLPLRKTFPIRINNGGNAAGARMSATAASSYAMALADVAKRNDTMELTVTDIEKLEQVFSDPQVLNFFANPTITVEKKRQVIDDIVKSSSLQSHTSNFLNVLVDANRINIVTEIVKEFELVYNKLTDTQLAEVRSVVKLEAPQLAQIAKQVQKLTGAKNVRVKTVIDASLVAGFTIRYGESGSKLIDMSVKKQLEDIASQLELGEIQLAT", "length": 234, "molWeight": 25669, "crc64": "78473309D02727DC", "md5": "9C4B1ED4BF1329996F7928BBCAAF987E"}}
{"primaryAccession": "Q9SUC5", "text": "This is Dihydroceramide fatty acyl 2-hydroxylase FAH2 protein, from Mouse-ear cress, contains 237 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SUC5", "organism_name": "Mouse-ear cress", "protein_name": "Dihydroceramide fatty acyl 2-hydroxylase FAH2", "length": 237, "firstPublicDate": "2012-10-03", "FUNCTION": "Fatty acid 2-hydroxylase involved in the alpha-hydroxylation of the long-chain fatty acid (LCFA) palmitic acid, Probably involved in the resistance response to oxidative stress", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the sterol desaturase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVAERYTVDLNKPLVFQVGHLGEEYQEWIHQPIVCVEGPRFFESDFWEFLTRTVWWAIPTIWLPVVCYVLSISASKGLTFPQIGLIVAFGVLTWTLLEYTLHRFLFHIQTKSYWANTAHYLLHGCHHKHPQDGLRLVFPPTATAILLVPLWKLLHLLATPATAPAILGGILFGYVMYDITHYYLHHGQPKEPTFKHLKKYHLNHHFRIQDKGYGITSSLWDKVFGTLPGIKAAAKKS", "length": 237, "molWeight": 27311, "crc64": "B89B31208E5AE87C", "md5": "556E03A15A592EEB4990E0FC4E427445"}}
{"primaryAccession": "Q9SV55", "text": "This is AFP homolog 2 protein, from Mouse-ear cress, contains 425 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SV55", "organism_name": "Mouse-ear cress", "protein_name": "AFP homolog 2", "length": 425, "firstPublicDate": "2009-04-14", "FUNCTION": "Acts as a transcriptional repressor, Negative regulator of jasmonate responses, Connects the JAZ proteins and the non-JAZ protein TIFY8 with the TOPLESS corepressors", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Ninja family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDDDNGLELSLGLSCGGSTGKAKGNNNNNAGSSSENYRAEGGDRSAKVIDDFKNFLHPTSQRPAEPSSGSQRSDSGQQPPQNFFNDLSKAPTTEAEASTKPLWVEDESRKEAGNKRKFGFPGMNDDKKKEKDSSHVDMHEKKTKASHVSTATDEGSTAENEDVAESEVGGGSSSNHAKEVVRPPTDTNIVDNLTGQRRSNHGGSGTEEFTMRNMSYTVPFTVHPQNVVTSMPYSLPTKESGQHAAATSLLQPNANAGNLPIMFGYSPVQLPMLDKDGSGGIVALSQSPFAGRVPSNSATAKGEGKQPVAEEGSSEDASERPTGDNSNLNTAFSFDFSAIKPGMAADVKFGGSGARPNLPWVSTTGSGPHGRTISGVTYRYNANQIKIVCACHGSHMSPEEFVRHASEEYVSPESSMGMTAASAHT", "length": 425, "molWeight": 44938, "crc64": "1796FB2FAAB0FB89", "md5": "A6E7EFA3681E0278B165E28FF6754D65"}}
{"primaryAccession": "Q9SV72", "text": "This is EPIDERMAL PATTERNING FACTOR-like protein 9 protein, from Mouse-ear cress, contains 102 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SV72", "organism_name": "Mouse-ear cress", "protein_name": "EPIDERMAL PATTERNING FACTOR-like protein 9", "length": 102, "firstPublicDate": "2010-03-23", "FUNCTION": "Positively regulates stomatal density and patterning, Acts by competing with EPF2 (AC Q8LC53) for the same receptors, ERECTA (AC Q42371) and TMM (AC Q9SSD1), Not cleaved by the protease CRSP (AC Q9LNU1) (PubMed:25043023)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the plant cysteine rich small secretory peptide family, Epidermal patterning factor subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKHEMMNIKPRCITIFFLLFALLLGNYVVQASRPRSIENTVSLLPQVHLLNSRRRHMIGSTAPTCTYNECRGCRYKCRAEQVPVEGNDPINSAYHYRCVCHR", "length": 102, "molWeight": 11840, "crc64": "B0918A267783A6DA", "md5": "3E833C70CC7A6F3527C183BDBA02F22E"}}
{"primaryAccession": "Q9SW18", "text": "This is Magnesium protoporphyrin IX methyltransferase, chloroplastic protein, from Mouse-ear cress, contains 312 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SW18", "organism_name": "Mouse-ear cress", "protein_name": "Magnesium protoporphyrin IX methyltransferase, chloroplastic", "length": 312, "firstPublicDate": "2013-06-26", "FUNCTION": "Converts Mg-protoporphyrin IX to Mg-protoporphyrin IX methylester using S-adenosyl-L-methionine as a cofactor, Involved in chloroplast-to-nucleus signaling by acting as a negative effector of nuclear photosynthetic gene expression", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the class I-like SAM-binding methyltransferase superfamily, Magnesium protoporphyrin O-methyltransferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPFAPSLLSSSSSVSQFLPRFPNATRFNVTPRSRAATVVAASVTDLAGVDSTTIAVLGGGSVAALAAMVSLTDPERRRKLQAEEVGGGDKEVVREYFNSTGFERWRKIYGETDEVNRVQKDIRLGHAKTVENTMLMLTEDRSLAGVTVCDAGCGTGLLSIPLAKEGAIVSASDISAAMVAEAEMKAKAQLPSENLPKFEVNDLESLTGKYDTVVCLDVLIHYPQNKADGMIAHLASLAEKRVILSFAPKTFYYDILKRIGELFPGPSKATRAYLHSEADVERALGKVGWKISKRGLTTTQFYFSRLIEAVPM", "length": 312, "molWeight": 33796, "crc64": "81A9C8611F2683A6", "md5": "5025B937DF0238485C670DF121190C29"}}
{"primaryAccession": "Q9SWH5", "text": "This is Galactoside 2-alpha-L-fucosyltransferase protein, from Mouse-ear cress, contains 558 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SWH5", "organism_name": "Mouse-ear cress", "protein_name": "Galactoside 2-alpha-L-fucosyltransferase", "length": 558, "firstPublicDate": "2002-03-05", "FUNCTION": "Involved in cell wall biosynthesis, Is both necessary and sufficient for the addition of the terminal fucosyl residue on xyloglucan side chains, but is not involved in the fucosylation of other cell wall components (PubMed:10373113, PubMed:11743104, PubMed:11854459, PubMed:14730072), Associates with other xyloglucan-synthesizing enzymes to form multiprotein complexes for xyloglucan synthesis in the Golgi (PubMed:25392066)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the glycosyltransferase 37 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDQNSYRRRSSPIRTTTGGSKSVNFSELLQMKYLSSGTMKLTRTFTTCLIVFSVLVAFSMIFHQHPSDSNRIMGFAEARVLDAGVFPNVTNINSDKLLGGLLASGFDEDSCLSRYQSVHYRKPSPYKPSSYLISKLRNYEKLHKRCGPGTESYKKALKQLDQEHIDGDGECKYVVWISFSGLGNRILSLASVFLYALLTDRVLLVDRGKDMDDLFCEPFLGMSWLLPLDFPMTDQFDGLNQESSRCYGYMVKNQVIDTEGTLSHLYLHLVHDYGDHDKMFFCEGDQTFIGKVPWLIVKTDNYFVPSLWLIPGFDDELNKLFPQKATVFHHLGRYLFHPTNQVWGLVTRYYEAYLSHADEKIGIQVRVFDEDPGPFQHVMDQISSCTQKEKLLPEVDTLVERSRHVNTPKHKAVLVTSLNAGYAENLKSMYWEYPTSTGEIIGVHQPSQEGYQQTEKKMHNGKALAEMYLLSLTDNLVTSAWSTFGYVAQGLGGLKPWILYRPENRTTPDPSCGRAMSMEPCFHSPPFYDCKAKTGIDTGTLVPHVRHCEDISWGLKLV", "length": 558, "molWeight": 63452, "crc64": "1BF0E372231A8ADF", "md5": "D89F5F11AB4687831AC11EBDF79F8583"}}
{"primaryAccession": "Q9SXJ6", "text": "This is ATP-dependent Clp protease proteolytic subunit 3, chloroplastic protein, from Mouse-ear cress, contains 309 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SXJ6", "organism_name": "Mouse-ear cress", "protein_name": "ATP-dependent Clp protease proteolytic subunit 3, chloroplastic", "length": 309, "firstPublicDate": "2007-11-13", "FUNCTION": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis, Has a chymotrypsin-like activity, Plays a major role in the degradation of misfolded proteins (By similarity), In the absence of CLPP3, modified ClpPR core(s) could be formed, albeit at strongly reduced levels (PubMed:23548781)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the peptidase S14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEMSLRLASSSTSNPICLLNPGKNLNFPIRNHRIPKTSKPFCVRSSMSLSKPPRQTLSSNWDVSSFSIDSVAQSPSRLPSFEELDTTNMLLRQRIVFLGSQVDDMTADLVISQLLLLDAEDSERDITLFINSPGGSITAGMGIYDAMKQCKADVSTVCLGLAASMGAFLLASGSKGKRYCMPNSKVMIHQPLGTAGGKATEMSIRIREMMYHKIKLNKIFSRITGKPESEIESDTDRDNFLNPWEAKEYGLIDAVIDDGKPGLIAPIGDGTPPPKTKVWDLWKVEGTKKDNTNLPSERSMTQNGYAAIE", "length": 309, "molWeight": 33925, "crc64": "0D2D0D3D1118AA0D", "md5": "548FDD6BEC401EC58BDA3996C7B12472"}}
{"primaryAccession": "Q9T041", "text": "This is Microtubule-associated protein TORTIFOLIA1 protein, from Mouse-ear cress, contains 864 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9T041", "organism_name": "Mouse-ear cress", "protein_name": "Microtubule-associated protein TORTIFOLIA1", "length": 864, "firstPublicDate": "2005-12-06", "FUNCTION": "Plant-specific microtubule-associated protein (MAP) that regulates the orientation of cortical microtubules and the direction of organ growth (PubMed:18577573), Determines microtubule organization by modulating microtubule severing (PubMed:24055158)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSTPTTSGSAAKPTRPARSSSLATRSCSNSGSLTSFQAMVELKQKILTSISKLADRDTYQIAVEDLEKTIQSLTPETLPMFLNCLYDSCSDPKPAVKKECLHLLSYVCSLHCDSTAAHLTKIIAQIVKRLKDSDSGVRDACRDTIGALSGIYLKGKEEGTNTGSASLAVGLFVKPLFEAMGEQNKVVQSGASMCMARMVESAASPPVTSFQKLCPRICKLLSNSSFLAKASLLPVVSSLSQVGAIAPQSLESLLESIHDCLGSTDWVTRKAAAETLTALASHSSGLIKEKTDSTITVLETCRFDKIKPVRESVTEALQLWKKISGKYVDGASDDSKLSASEQLGSEKNGEKRSNLADLMKKEASDGSTLSPDSASKGKGCFPEKAVGLLKKKAPVLSDKDFNPEFFQRLERRQSVEVVVPRRCKNNDEEESGLDDLNAMGSSNRLKNTQADDKQVKGRFDGNGSQARTSGDDKAGVVNGKETPGHHAPVSNTDNQSEGSFTSNRGNWSAIQRQLLQLERQQTNLMNMLQEFIGGSHDSMVTLEGRVRGLERIVEDMARDLSISSGRRANLTAGFGKYNSFANYPTGKYNGRAPGERGSQTDGAMRGRMWNSDMADDWFIPPHAASRNGQAGPRRSPRSEQYENEHMGNGRRGWDNKASGTIRFGEGPSARSVWQASKDEATLEAIRVAGEDGAVPRPTRVAVAPEAEAMGDDDNEGQERDPIWVSWSNAMHSLRVGDIDAAYAEVLCAGDQHLVIKLMDKTGPSLDQMSNEIANEALNFISQFLLDHSLYDICLSWSQQLLELVLQDGADTFGVPMELKTEILYNLQDACSTMDPPEDWEGPAPEQLVVQLASVWEIDLQQFDK", "length": 864, "molWeight": 94004, "crc64": "4A6191A5D90E71A4", "md5": "BA1EAC04279860A559CD5AF41D84D0CA"}}
{"primaryAccession": "Q9TU31", "text": "This is Parathyroid hormone/parathyroid hormone-related peptide receptor protein, from Dog, contains 595 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9TU31", "organism_name": "Dog", "protein_name": "Parathyroid hormone/parathyroid hormone-related peptide receptor", "length": 595, "firstPublicDate": "2006-10-03", "FUNCTION": "Receptor for parathyroid hormone and for parathyroid hormone-related peptide, The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGAVRIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCQKRLKEVLQRPADIMESDKGWASASTSGKPKKEKASGKLYPESEEDKEVPTGSRHRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPTAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRAGLGLPLSPRLLPAAAATTTATTNGHPPIPGHTKPGAPTLPATPPATAAPKDDGFLNGSCSGLDEEASAPERPPALLQEEWETVM", "length": 595, "molWeight": 66309, "crc64": "09568ECF38D4D258", "md5": "99B90685776A1AB1C30FD954E0B8A8E2"}}
{"primaryAccession": "Q9TWL9", "text": "This is Conodipine-M alpha chain protein, from Magical cone, contains 77 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9TWL9", "organism_name": "Magical cone", "protein_name": "Conodipine-M alpha chain", "length": 77, "firstPublicDate": "2002-05-02", "FUNCTION": "Heterodimer: conodipine-M catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, This activity may be supported by the alpha chain, Conodipine-M inhibits the binding of isradipine (a ligand specific for L-type calcium channel) to L-type calcium channels", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the phospholipase A2 family, Group IX subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "QXPSTAELCKINSNACSVPFSXIPCQKXFLAACDRHDTCYHCGKHFGFKQDDCDDAFFRDMTALCAHGTDDEGXCPX", "length": 77, "molWeight": 8492, "crc64": "73861D7587479D8C", "md5": "2F930A17299398B0B81DAF18AA17728A"}}
{"primaryAccession": "Q9TYU9", "text": "This is Excretory canal abnormal protein 6 protein, from Caenorhabditis elegans, contains 843 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9TYU9", "organism_name": "Caenorhabditis elegans", "protein_name": "Excretory canal abnormal protein 6", "length": 843, "firstPublicDate": "2015-09-16", "FUNCTION": "Constitutively active protein required for microtubule and F-actin growth, structural maintenance and organization during excretory cell tubulogenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the formin homology family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTSDTIRQTLDELLLDKNGGSSNEARAFFLSQIIDQLKLISSQTDAERQLQKLQLKDPNDNIVKATPPPPPPPPPLISILQQAPPPPPPPPPPTLKAPPPPPILGLKTPSKSLKTPTPRPKECPTSFLPKKEKKTKTRTVQWSKINASVVQDDSVWGKLAKASNVDIDFDLLDNFFGIESLAVSGAAEVVKKSTRKDAHVELLTAKRSQNVAIMLKQFKNIDELIDDVSQNKPVAEIDALQNLFGMLPQSEEEEALRRYTGDISLLSPPSSFFYRLVQIQFYRLRIETQIFLSDFSRLMRELAPNVEILIRTSQEILTSPTLPRLLLIFVNMGNYLNGNNSQGNAFGFTLNSLWKLIDLKGNKQEFSLLHLLVTCEPDLVAHLQEELSTLKDASQISFDEIKISLKTLRDGRCKLEKQLETCSGASFTQFLELIKIDCKFELDEFGANYDKLTELQYQLADYFCENRNTFQLDECLKIFNFLMNRLQQTLKEHVTRETRKLKKEEKKETQTTRECEKTMKKPEKIDLFDALTASNGGPESPRKRAAGILDMRQKLGNVRIRKLRDVTTLESSFTPPPPPPLESPTDSTSSKENESVKPAKTSTNYEMCNDLESYITSLTRKRASHLPKAPPKEEPKLPEVLPEKSKIALKIEKIPEKIDKPPLPQAAPIIPKLPQKSIKAPSTVTTRSKVPPPTAAAAVRIVSVTTTTTPTKTAELRKPGARSPKTTVATVPKVTVVPVSRVPVAPSTPLSRRMSAPVVRKPTMTAEKKREITMKPSVSTSARPSLINTSSHPMVRSPLPKMSVLEKPKPLRITRPTVIPQSPTVTSSARPSGLRQPAKPKWV", "length": 843, "molWeight": 94062, "crc64": "75D065713C12CA50", "md5": "F80E8898A7E9A0A1E64A2A86650A04DE"}}
{"primaryAccession": "Q9U3C8", "text": "This is Defective in cullin neddylation protein 1 protein, from Caenorhabditis elegans, contains 295 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9U3C8", "organism_name": "Caenorhabditis elegans", "protein_name": "Defective in cullin neddylation protein 1", "length": 295, "firstPublicDate": "2005-08-30", "FUNCTION": "Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes, Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity, Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with rbx-1 to recruit the Nedd8-charged E2 enzyme to the cullin component of SCF-type complexes", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNRLKSDQKTKLRQFVQWTQVTEAVSLNFLAKANWNIEYAMTLYFDNPNLFAGSTPQPSVDRSNIERLFNQYVDPKDKVGEKRMGPHGINRLLTDLGYEATDRRVLVLAWKFTAQTQCEFSLDEWVKGMTALQADTVQNLRQRIDSINSGLESDKAKFHELYLFAFNYAKSAACRNLDLETAICCWDVLFGQRSTIMTQWIDFLWAQENAAASRLAQNVGASNAKQFKSVWISRDTWNLFWDFILLSKPDLSDYDDEGAWPVLIDQFVDYCRENLNYPKPGNASNDQQMETPSYY", "length": 295, "molWeight": 34133, "crc64": "F5C50912727235E4", "md5": "1BB3ED9AF2B044B0BE52C348D7FD3E6F"}}
{"primaryAccession": "Q9U6M1", "text": "This is Thymine dioxygenase JBP1 protein, from Sauroleishmania tarentolae, contains 827 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9U6M1", "organism_name": "Sauroleishmania tarentolae", "protein_name": "Thymine dioxygenase JBP1", "length": 827, "firstPublicDate": "2009-06-16", "FUNCTION": "Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU), DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation, Also specifically binds to base J-containing DNA (J-DNA), Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized DNA base J and propagating J synthesis, Thymine dioxygenase activity and J-DNA-binding are independent functions", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TET family, JBP1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEPDSKKVKLDIFNFPTTRETRTPEEVAESYAEAVKSHPFYDNVHSVVDFYDSGTIKDGRGQIIGVVLREALPKYAASMASELLTSAAVRTSLRSMMFGGEPPLSGIAGYFDYRGSPVELKSRKTSFTYEHEAAWPAVFPVVDYVSEIYRHVAPERWKAQNDAIPDLVRIHGTPFSTLTINSRFRTASHTDVGDFDAGYSCIACLDGQFKGLALSFDDFGINVLLQPRDVMIFDSHHFHSNTEVELSFSGEDWKRLTCVFYYRAALGEPASYAEYQRRLEKSKTDTRFTPVVHHVRVKENGTSVNRPSPVYPISQSPFWVPMVAHCLQHCASAAQCVHEAMTADGSRLAEMMFGESLSTSDGIPLRGEDEKVKANGDSTPRPLSRLGGFSETNLMVSTAVEKKKYLDSEFLLHCISAQLLDMWKQARARWLELVGKEWAHMLALNPERKDFLWKNQSEMNSAFFDLCEVGKQVMLGLLGKEVALPKEEQAFWIMYAVHLSAACAEELHMPEVAMSLRKLNVKLKDFNFGGTRYFKDMPPEEKKRRMERKQRIEEARRHGMPSGSHEKRANWLTNDSFDYQTEDCVIDYAQHKWVLPALHAKEVTKTVRTGELPTTERVVRVLVVIPDPQSKLENVDCKLEVPDMVGSSSEWERLMSSPAVHRVLSAAQRNLQLPDSVTHGNVQTHFAFHSTLPTDIYDFVVLQHVLSRIPDDAQASAYIRRAAALCSGCLFVVETDVQCRQYYTLKYSIRCSYDTVAPLFFQQLHRVCYGTKTARVRTKGELESLIPTVCCARYKLQGSPLNTTVHVVSPFPSCEVQNLSSALCDRA", "length": 827, "molWeight": 93403, "crc64": "5A4B502DE70A4BFE", "md5": "01692C18065FD4109BF1AE6D85C0EC57"}}
{"primaryAccession": "Q9U7C9", "text": "This is Nucleomorphin protein, from Social amoeba, contains 756 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9U7C9", "organism_name": "Social amoeba", "protein_name": "Nucleomorphin", "length": 756, "firstPublicDate": "2007-07-10", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDLDYSSDNSRLVADNQNNKTNTKNQSQLSTSSQIPQTSQSYQQQQQHNQQQQQQQQQKQNSRPSSPKTIQAKVNNNNNNNNNNNNNNNNNNNNGATISHPPTSQSNEDLSSSAEIHHDDSAQLNSNIFENLGFVIDITINLKRKMELVKIIKKNGGKSCYSCTKATHLITTKQGYLEKTQKVTQAISLGIPILVKEYVHYCAFKKELLGVENYLVSSLILNPTSTTLNSSQDLIEKPNEEEPQNGTINEQPIAMTIDNTLESNKPIETIQPSSLEKQEPKETELQTQQQPQTELKSELEPQQLQLIQEKDKNINNLSIDSNHMDTSKIEAGNNISNQTQSNIISSVVQTIEPLKECNKIDLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSNNKNKNNVDEAQEGLNINSVMDVHLTSSTSSTLSSSDNQDNELLRDEGTTPKSKKKFSQKKNHLLNLKKSYQDPEIIAHSRPRKSSGGVSLVEALSDHANYISNLDGFKYYARANKSSLNSNATTSGGNNRSIKLNEYKYDDEEEDEEDEDEEDEEEDEEEEEEEEEEEEDYDDEDLNDEESDEDDFDSDEDVSRFIKGKLLQKQQKIYKDLERFEHSRQQQHHHHQSSQVNSSKPRSRSHSRDYIESEIAKYLLNNSEKQIPLSPTKKRSLSNQFHQDGGNNTTDGNLFNNFSTNGGGNRTNIDDSIKQSILESPSSSSLKSSKSKKSKKPFLPPLSTLVHILVTFIILSAFFMSLPSN", "length": 756, "molWeight": 85404, "crc64": "C5DF0DB1A281C836", "md5": "6D946F63B48879915D33986EFC65B65F"}}
{"primaryAccession": "Q9UBC1", "text": "This is NF-kappa-B inhibitor-like protein 1 protein, from Human, contains 381 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UBC1", "organism_name": "Human", "protein_name": "NF-kappa-B inhibitor-like protein 1", "length": 381, "firstPublicDate": "2004-03-01", "FUNCTION": "Involved in the regulation of innate immune response, Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways, Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK", "length": 381, "molWeight": 43257, "crc64": "1BD72901881384EC", "md5": "E86F2FD7FA0882145C6F713D2A7936B0"}}
{"primaryAccession": "Q9UBU7", "text": "This is Protein DBF4 homolog A protein, from Human, contains 674 amino acids, has 1 DBF4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [289, 337], "description": "DBF4-type", "keyword_description": "Zinc finger", "textural_description": "DBF4-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9UBU7", "organism_name": "Human", "protein_name": "Protein DBF4 homolog A", "length": 674, "firstPublicDate": "2006-05-02", "FUNCTION": "Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation, Required for progression of S phase, The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"DBF4-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEKSKCKPLWGKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLGRISPVPSPESAYTAETTSPHPSHDGSSFKSPDTVCLSRGKLLVEKAIKDHDFIPSNSILSNALSWGVKILHIDDIRYYIEQKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDKPSSMQKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIFTHDSGLITINSSQEHLTVQAKAPFHTPPEEPNECDFKNMDSLPSGKIHRKVKIILGRNRKENLEPNAEFDKRTEFITQEENRICSSPVQSLLDLFQTSEEKSEFLGFTSYTEKSGICNVLDIWEEENSDNLLTAFFSSPSTSTFTGF", "length": 674, "molWeight": 76858, "crc64": "353FEB7E85507E5C", "md5": "FB2E12415A6E714D27CAD44DB2AEC35B"}}
{"primaryAccession": "Q9UDW3", "text": "This is Zinc finger matrin-type protein 5 protein, from Human, contains 170 amino acids, has 1 C3H1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [51, 79], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9UDW3", "organism_name": "Human", "protein_name": "Zinc finger matrin-type protein 5", "length": 170, "firstPublicDate": "2006-10-31", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C3H1-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKVWYDMFRDAAAILLDEQNKRPCRKFLLTGQCDFGSNCRFSHMSERDLQELSIQVEEERRAREWLLDAPELPEGHLEDWLEKRAKRLSSAPSSRAEPIRTTVFQYPVGWPPVQELPPSLRAPPPGGWPLQPRVQWG", "length": 170, "molWeight": 19971, "crc64": "FEBF7BD946EFA5FA", "md5": "A7695135A9E520642F987C23E728214D"}}
{"primaryAccession": "Q9UFE4", "text": "This is Coiled-coil domain-containing protein 39 protein, from Human, contains 941 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UFE4", "organism_name": "Human", "protein_name": "Coiled-coil domain-containing protein 39", "length": 941, "firstPublicDate": "2006-05-16", "FUNCTION": "Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella (PubMed:21131972), Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity), Not required for outer dynein arm complexes assembly (PubMed:21131972)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CCDC39 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSEFLAELHWEDGFAIPVANEENKLLEDQLSKLKDERASLQDELREYEERINSMTSHFKNVKQELSITQSLCKARERETESEEHFKAIAQRELGRVKDEIQRLENEMASILEKKSDKENGIFKATQKLDGLKCQMNWDQQALEAWLEESAHKDSDALTLQKYAQQDDNKIRALTLQLERLTLECNQKRKILDNELTETISAQLELDKAAQDFRKIHNERQELIKQWENTIEQMQKRDGDIDNCALELARIKQETREKENLVKEKIKFLESEIGNNTEFEKRISVADRKLLKCRTAYQDHETSRIQLKGELDSLKATVNRTSSDLEALRKNISKIKKDIHEETARLQKTKNHNEIIQTKLKEITEKTMSVEEKATNLEDMLKEEEKDVKEVDVQLNLIKGVLFKKAQELQTETMKEKAVLSEIEGTRSSLKHLNHQLQKLDFETLKQQEIMYSQDFHIQQVERRMSRLKGEINSEEKQALEAKIVELRKSLEEKKSTCGLLETQIKKLHNDLYFIKKAHSKNSDEKQSLMTKINELNLFIDRSEKELDKAKGFKQDLMIEDNLLKLEVKRTREMLHSKAEEVLSLEKRKQQLYTAMEERTEEIKVHKTMLASQIRYVDQERENISTEFRERLSKIEKLKNRYEILTVVMLPPEGEEEKTQAYYVIKAAQEKEELQREGDCLDAKINKAEKEIYALENTLQVLNSCNNNYKQSFKKVTPSSDEYELKIQLEEQKRAVDEKYRYKQRQIRELQEDIQSMENTLDVIEHLANNVKEKLSEKQAYSFQLSKETEEQKPKLERVTKQCAKLTKEIRLLKDTKDETMEEQDIKLREMKQFHKVIDEMLVDIIEENTEIRIILQTYFQQSGLELPTASTKGSRQSSRSPSHTSLSARSSRSTSTSTSQSSIKVLELKFPASSSLVGSPSRPSSASSSSSNVKSKKSSK", "length": 941, "molWeight": 109901, "crc64": "1B7DAFB1B9A30D14", "md5": "D25213699E34392528A24543978D5480"}}
{"primaryAccession": "Q9UGK3", "text": "This is Signal-transducing adaptor protein 2 protein, from Human, contains 403 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UGK3", "organism_name": "Human", "protein_name": "Signal-transducing adaptor protein 2", "length": 403, "firstPublicDate": "2005-04-12", "FUNCTION": "Substrate of protein kinase PTK6, May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHVEKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELRVPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPTAGLADMTAELQKKLEKRRALEH", "length": 403, "molWeight": 44894, "crc64": "A5E809B3F233EFD0", "md5": "E8C895A2F63166D2AC538B58A4069EEF"}}
{"primaryAccession": "Q9UHR5", "text": "This is SAP30-binding protein protein, from Human, contains 308 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UHR5", "organism_name": "Human", "protein_name": "SAP30-binding protein", "length": 308, "firstPublicDate": "2006-07-11", "FUNCTION": "(Microbial infection) Involved in transcriptional repression of HHV-1 genes TK and gC", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the HCNGP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGKKNVLSSLAVYAEDSEPESDGEAGIEAVGSAAEEKGGLVSDAYGEDDFSRLGGDEDGYEEEEDENSRQSEDDDSETEKPEADDPKDNTEAEKRDPQELVASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATSTTTTTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "length": 308, "molWeight": 33870, "crc64": "C48CEFBD73CE82BC", "md5": "E18CD69DFA06D777DD8DCAB81E9EB705"}}
{"primaryAccession": "Q9UIH9", "text": "This is Krueppel-like factor 15 protein, from Human, contains 416 amino acids, has 3 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [321, 345], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [351, 375], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [381, 403], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9UIH9", "organism_name": "Human", "protein_name": "Krueppel-like factor 15", "length": 416, "firstPublicDate": "2002-01-23", "FUNCTION": "Transcriptional regulator that binds to the GA element of the CLCNKA promoter, Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart (By similarity), Is a repressor of CCN2 expression, involved in the control of cardiac fibrosis, It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4 (By similarity), Involved in podocyte differentiation (By similarity), Inhibits MYOCD activity, Is a negative regulator of TP53 acetylation, Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Sp1 C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 3}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVDHLLPVDENFSSPKCPVGYLGDRLVGRRAYHMLPSPVSEDDSDASSPCSCSSPDSQALCSCYGGGLGTESQDSILDFLLSQATLGSGGGSGSSIGASSGPVAWGPWRRAAAPVKGEHFCLPEFPLGDPDDVPRPFQPTLEEIEEFLEENMEPGVKEVPEGNSKDLDACSQLSAGPHKSHLHPGSSGRERCSPPPGGASAGGAQGPGGGPTPDGPIPVLLQIQPVPVKQESGTGPASPGQAPENVKVAQLLVNIQGQTFALVPQVVPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGPAGLLMGQKFPKNPAAELIKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSSRSVRSVN", "length": 416, "molWeight": 43992, "crc64": "6335F85141BEB276", "md5": "141105E905BDC7FC44455274D34D45C2"}}
{"primaryAccession": "Q9UII2", "text": "This is ATPase inhibitor, mitochondrial protein, from Human, contains 106 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UII2", "organism_name": "Human", "protein_name": "ATPase inhibitor, mitochondrial", "length": 106, "firstPublicDate": "2001-01-24", "FUNCTION": "Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix, Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase, Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the ATPase inhibitor family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAVTALAARTWLGVWGVRTMQARGFGSDQSENVDRGAGSIREAGGAFGKREQAEEERYFRAQSREQLAALKKHHEEEIVHHKKEIERLQKEIERHKQKIKMLKHDD", "length": 106, "molWeight": 12249, "crc64": "A6144431125D5A86", "md5": "42534BE598228DA1FC760A06072703A4"}}
{"primaryAccession": "Q9UJA3", "text": "This is DNA helicase MCM8 protein, from Human, contains 840 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UJA3", "organism_name": "Human", "protein_name": "DNA helicase MCM8", "length": 840, "firstPublicDate": "2003-01-17", "FUNCTION": "Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR) (PubMed:23401855), Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity (PubMed:26215093), Probably by regulating the localization of the MNR complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs (PubMed:23401855), The MCM8-MCM9 complex is dispensable for DNA replication and S phase progression (PubMed:23401855), However, may play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC) (PubMed:15684404), Probably by regulating HR, plays a key role during gametogenesis (By similarity), Stabilizes MCM9 protein (PubMed:23401855, PubMed:26215093)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCM family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFISALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM", "length": 840, "molWeight": 93697, "crc64": "6349339A92FEBF88", "md5": "1179947C51F8B13CF079C98C282DBF84"}}
{"primaryAccession": "Q9UK96", "text": "This is F-box only protein 10 protein, from Human, contains 956 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UK96", "organism_name": "Human", "protein_name": "F-box only protein 10", "length": 956, "firstPublicDate": "2001-02-21", "FUNCTION": "Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, Mediates the ubiquitination and degradation of BCL2, an antiapoptotic protein, thereby playing a role in apoptosis by controlling the stability of BCL2, Targets also the receptor for advanced glycation end products RAGE for ubiquitination and subsequent lysosomal degradation (PubMed:28515150), Directly controls HGAL/GCSAM ubiquitination and degradation and thereby decreases BCR signaling (PubMed:31570756)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEAGGLPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNWPNQPDVEPESWREAFKQHYLASKTWTKNALDLESSICFSLFRRRRERRTLSVGPGREFDSLGSALAMASLYDRIVLFPGVYEEQGEIILKVPVEIVGQGKLGEVALLASIDQHCSTTRLCNLVFTPAWFSPIMYKTTSGHVQFDNCNFENGHIQVHGPGTCQVKFCTFKNTHIFLHNVPLCVLENCEFVGSENNSVTVEGHPSADKNWAYKYLLGLIKSSPTFLPTEDSDFLMSLDLESRDQAWSPKTCDIVIEGSQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSPSGEDEDEDQLMYRLSYQVQGPRPVLGGSFLGPPLPGASIQLPSCLVLNSLQQELQKDKEAMALANSVQGCLIRKCLFRDGKGGVFVCSHGRAKMEGNIFRNLTYAVRCIHNSKIIMLRNDIYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESNSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIENDIIGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQENIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKSDTWRLVNPPARPHLENSLRRPSAAHNGQKVTAMATRITARVEGGYHSNRSVFCTIL", "length": 956, "molWeight": 105195, "crc64": "3F9BDEBE0139B16F", "md5": "C01CEF5A28E84CABDC5F07305073B0DC"}}
{"primaryAccession": "Q9UK97", "text": "This is F-box only protein 9 protein, from Human, contains 447 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UK97", "organism_name": "Human", "protein_name": "F-box only protein 9", "length": 447, "firstPublicDate": "2001-02-21", "FUNCTION": "Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability (PubMed:34480022, PubMed:23263282), Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation, In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex, As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1 (PubMed:23263282), Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway (PubMed:34480022), Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPDIIWVFPPQAEAEEDCHSDTVRADDDEENESPAETDLQAQLQMFRAQWMFELAPGVSSSNLENRPCRAARGSLQKTSADTKGKQEQAKEEKARELFLKAVEEEQNGALYEAIKFYRRAMQLVPDIEFKITYTRSPDGDGVGNSYIEDNDDDSKMADLLSYFQQQLTFQESVLKLCQPELESSQIHISVLPMEVLMYIFRWVVSSDLDLRSLEQLSLVCRGFYICARDPEIWRLACLKVWGRSCIKLVPYTSWREMFLERPRVRFDGVYISKTTYIRQGEQSLDGFYRAWHQVEYYRYIRFFPDGHVMMLTTPEEPQSIVPRLRTRNTRTDAILLGHYRLSQDTDNQTKVFAVITKKKEEKPLDYKYRYFRRVPVQEADQSFHVGLQLCSSGHQRFNKLIWIHHSCHITYKSTGETAVSAFEIDKMYTPLFFARVRSYTAFSERPL", "length": 447, "molWeight": 52329, "crc64": "2A88163DAB898D69", "md5": "79CE8D4C0C9F37230E15C98D3F3A489F"}}
{"primaryAccession": "Q9UKF6", "text": "This is Cleavage and polyadenylation specificity factor subunit 3 protein, from Human, contains 684 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UKF6", "organism_name": "Human", "protein_name": "Cleavage and polyadenylation specificity factor subunit 3", "length": 684, "firstPublicDate": "2001-10-18", "FUNCTION": "Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition, Has endonuclease activity, and functions as mRNA 3'-end-processing endonuclease (PubMed:30507380), Also involved in the histone 3'-end pre-mRNA processing (PubMed:30507380), U7 snRNP-dependent protein that induces both the 3'-endoribonucleolytic cleavage of histone pre-mRNAs and acts as a 5' to 3' exonuclease for degrading the subsequent downstream cleavage product (DCP) of mature histone mRNAs, Cleavage occurs after the 5'-ACCCA-3' sequence in the histone pre-mRNA leaving a 3'hydroxyl group on the upstream fragment containing the stem loop (SL) and 5' phosphate on the downstream cleavage product (DCP) starting with CU nucleotides, The U7-dependent 5' to 3' exonuclease activity is processive and degrades the DCP RNA substrate even after complete removal of the U7-binding site, Binds to the downstream cleavage product (DCP) of histone pre-mRNAs and the cleaved DCP RNA substrate in a U7 snRNP dependent manner, Required for entering/progressing through S-phase of the cell cycle (PubMed:30507380), Required for the selective processing of microRNAs (miRNAs) during embryonic stem cell differentiation via its interaction with ISY1 (By similarity), Required for the biogenesis of all miRNAs from the pri-miR-17-92 primary transcript except miR-92a (By similarity), Only required for the biogenesis of miR-290 and miR-96 from the pri-miR-290-295 and pri-miR-96-183 primary transcripts, respectively (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSAIPAEESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNISADDMLYTETDLEESMDKIETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQININNPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMGFLADKKPEQGQRVSGILVKRNFNYHILSPCDLSNYTDLAMSTVKQTQAIPYTGPFNLLCYQLQKLTGDVEELEIQEKPALKVFKNITVIQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYSKRLEIMLQDIFGEDCVSVKDDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEALTPVH", "length": 684, "molWeight": 77486, "crc64": "F8AA24EA6FB78377", "md5": "8F63FB3B0E0B583DB9906CAEB3DB8AC1"}}
{"primaryAccession": "Q9UKV5", "text": "This is E3 ubiquitin-protein ligase AMFR protein, from Human, contains 643 amino acids, has 1 RING-type Zinc finger, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [{"location": [341, 379], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9UKV5", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase AMFR", "length": 643, "firstPublicDate": "2003-09-19", "FUNCTION": "E3 ubiquitin-protein ligase that mediates the polyubiquitination of lysine and cysteine residues on target proteins, such as CD3D, CYP3A4, CFTR, INSIG1, SOAT2/ACAT2 and APOB for proteasomal degradation (PubMed:10456327, PubMed:11724934, PubMed:12670940, PubMed:19103148, PubMed:24424410, PubMed:28604676), Component of a VCP/p97-AMFR/gp78 complex that participates in the final step of endoplasmic reticulum-associated degradation (ERAD) (PubMed:10456327, PubMed:11724934, PubMed:19103148, PubMed:24424410), The VCP/p97-AMFR/gp78 complex is involved in the sterol-accelerated ERAD degradation of HMGCR through binding to the HMGCR-INSIG1 complex at the ER membrane (PubMed:16168377, PubMed:22143767), In addition, interaction of AMFR with AUP1 facilitates interaction of AMFR with ubiquitin-conjugating enzyme UBE2G2 and ubiquitin ligase RNF139, leading to sterol-induced HMGCR ubiquitination (PubMed:23223569), The ubiquitinated HMGCR is then released from the ER into the cytosol for subsequent destruction (PubMed:16168377, PubMed:22143767, PubMed:23223569), In addition to ubiquitination on lysine residues, catalyzes ubiquitination on cysteine residues: together with INSIG1, mediates polyubiquitination of SOAT2/ACAT2 at 'Cys-277', leading to its degradation when the lipid levels are low (PubMed:28604676), Catalyzes ubiquitination and subsequent degradation of INSIG1 when cells are depleted of sterols (PubMed:17043353), Mediates polyubiquitination of INSIG2 at 'Cys-215' in some tissues, leading to its degradation (PubMed:31953408), Also regulates ERAD through the ubiquitination of UBL4A a component of the BAG6/BAT3 complex (PubMed:21636303), Also acts as a scaffold protein to assemble a complex that couples ubiquitination, retranslocation and deglycosylation (PubMed:21636303), Mediates tumor invasion and metastasis as a receptor for the GPI/autocrine motility factor (PubMed:10456327), In association with LMBR1L and UBAC2, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 (PubMed:31073040), Regulates NF-kappa-B and MAPK signaling pathways by mediating 'Lys-27'-linked polyubiquitination of TAB3 and promoting subsequent TAK1/MAP3K7 activation (PubMed:36593296)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPLLFLERFPWPSLRTYTGLSGLALLGTIISAYRALSQPEAGPGEPDQLTASLQPEPPAPARPSAGGPRARDVAQYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLLSCCGLAAVCSITGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYYTDFVMELTLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARFAVATPEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIADNNRVREEHQGENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIASWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQLTRSVEITTDNILEGRIQVPFPTQRSDSIRPALNSPVERPSSDQEEGETSAQTERVPLDLSPRLEETLDFGEVEVEPSEVEDFEARGSRFSKSADERQRMLVQRKDELLQQARKRFLNKSSEDDAASESFLPSEGASSDPVTLRRRMLAAAAERRLQKQQTS", "length": 643, "molWeight": 72996, "crc64": "8782324609C0E62A", "md5": "2D887653EDE49ABED796AD24BBB1496C"}}
{"primaryAccession": "Q9UL51", "text": "This is Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 protein, from Human, contains 889 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UL51", "organism_name": "Human", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "length": 889, "firstPublicDate": "2003-02-28", "FUNCTION": "Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions, Contributes to the native pacemaker currents in heart (If) and in neurons (Ih), Can also transport ammonium in the distal nephron, Produces a large instantaneous current, Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the potassium channel HCN family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDARGGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSEEAGPAGEPRGSQASFMQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLNSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGLFPPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAAGGLDPQDSARSRLSSNL", "length": 889, "molWeight": 96950, "crc64": "4B263E0C06C2A47D", "md5": "19163822D53EF06530F0730234FDE9A6"}}
{"primaryAccession": "Q9UL62", "text": "This is Short transient receptor potential channel 5 protein, from Human, contains 973 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UL62", "organism_name": "Human", "protein_name": "Short transient receptor potential channel 5", "length": 973, "firstPublicDate": "2000-12-01", "FUNCTION": "Thought to form a receptor-activated non-selective calcium permeant cation channel, Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors, Has also been shown to be calcium-selective (By similarity), May also be activated by intracellular calcium store depletion, Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1 (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the transient receptor (TC 1,A,4) family, STrpC subfamily, TRPC5 sub-subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGNRKHPRSFSTSSTELSQRDDNNDGSGGARAKSKSVSFNLGCKKKTCHGPPLIRTMPRSSGAQGKSKAESSSKRSFMGPSLKKLGLLFSKFNGHMSEPSSEPMYTISDGIVQQHCMWQDIRYSQMEKGKAEACSQSEINLSEVELGEVQGAAQSSECPLACSSSLHCASSICSSNSKLLDSSEDVFETWGEACDLLMHKWGDGQEEQVTTRL", "length": 973, "molWeight": 111412, "crc64": "FBC8CBF17BE42166", "md5": "BB10AE6C351D27C749C0AC9FBE1C3F60"}}
{"primaryAccession": "Q9ULC6", "text": "This is Protein-arginine deiminase type-1 protein, from Human, contains 663 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ULC6", "organism_name": "Human", "protein_name": "Protein-arginine deiminase type-1", "length": 663, "firstPublicDate": "2001-01-11", "FUNCTION": "Catalyzes the deimination of arginine residues of proteins", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein arginine deiminase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAPKRVVQLSLKMPTHAVCVVGVEAHVDIHSDVPKGANSFRVSGSSGVEVFMVYNRTRVKEPIGKARWPLDTDADMVVSVGTASKELKDFKVRVSYFGEQEDQALGRSVLYLTGVDISLEVDTGRTGKVKRSQGDKKTWRWGPEGYGAILLVNCDRDNHRSAEPDLTHSWLMSLADLQDMSPMLLSCNGPDKLFDSHKLVLNVPFSDSKRVRVFCARGGNSLSDYKQVLGPQCLSYEVERQPGEQEIKFYVEGLTFPDADFLGLVSLSVSLVDPGTLPEVTLFTDTVGFRMAPWIMTPNTQPPEELYVCRVMDTHGSNEKFLEDMSYLTLKANCKLTICPQVENRNDRWIQDEMEFGYIEAPHKSFPVVFDSPRNRGLKDFPYKRILGPDFGYVTREIPLPGPSSLDSFGNLDVSPPVTVGGTEYPLGRILIGSSFPKSGGRQMARAVRNFLKAQQVQAPVELYSDWLSVGHVDEFLTFVPTSDQKGFRLLLASPSACLKLFQEKKEEGYGEAAQFDGLKHQAKRSINEMLADRHLQRDNLHAQKCIDWNRNVLKRELGLAESDIVDIPQLFFLKNFYAEAFFPDMVNMVVLGKYLGIPKPYGPIINGRCCLEEKVQSLLEPLGLHCIFIDDYLSYHELQGEIHCGTNVRRKPFPFKWWNMVP", "length": 663, "molWeight": 74666, "crc64": "4674CEBC03A7E7CA", "md5": "6A3E23E18A7CCAFAA21262C0038AB6F6"}}
{"primaryAccession": "Q9UM63", "text": "This is Zinc finger protein PLAGL1 protein, from Human, contains 463 amino acids, has 7 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [4, 26], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [32, 56], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [62, 84], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [91, 113], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [120, 142], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [156, 178], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [184, 207], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9UM63", "organism_name": "Human", "protein_name": "Zinc finger protein PLAGL1", "length": 463, "firstPublicDate": "2001-06-20", "FUNCTION": "Acts as a transcriptional activator (PubMed:9722527), Involved in the transcriptional regulation of type 1 receptor for pituitary adenylate cyclase-activating polypeptide", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 7}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATFPCQLCGKTFLTLEKFTIHNYSHSRERPYKCVQPDCGKAFVSRYKLMRHMATHSPQKSHQCAHCEKTFNRKDHLKNHLQTHDPNKMAFGCEECGKKYNTMLGYKRHLALHAASSGDLTCGVCALELGSTEVLLDHLKAHAEEKPPSGTKEKKHQCDHCERCFYTRKDVRRHLVVHTGCKDFLCQFCAQRFGRKDHLTRHTKKTHSQELMKESLQTGDLLSTFHTISPSFQLKAAALPPFPLGASAQNGLASSLPAEVHSLTLSPPEQAAQPMQPLPESLASLHPSVSPGSPPPPLPNHKYNTTSTSYSPLASLPLKADTKGFCNISLFEDLPLQEPQSPQKLNPGFDLAKGNAGKVNLPKELPADAVNLTIPASLDLSPLLGFWQLPPPATQNTFGNSTLALGPGESLPHRLSCLGQQQQEPPLAMGTVSLGQLPLPPIPHVFSAGTGSAILPHFHHAFR", "length": 463, "molWeight": 50819, "crc64": "B10C74DA409BD4F7", "md5": "292254479ABD847EB1432786E3C60AD2"}}
{"primaryAccession": "Q9UNL4", "text": "This is Inhibitor of growth protein 4 protein, from Human, contains 249 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [196, 245], "description": "PHD-type", "keyword_description": "Zinc finger", "textural_description": "PHD-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9UNL4", "organism_name": "Human", "protein_name": "Inhibitor of growth protein 4", "length": 249, "firstPublicDate": "2005-01-04", "FUNCTION": "Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4 (PubMed:16387653), Through chromatin acetylation it may function in DNA replication (PubMed:16387653), May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation (PubMed:15251430, PubMed:15528276), Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA (PubMed:15029197), May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC (PubMed:15029197), Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1) (PubMed:15897452), Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ING family", "domain_description": {"PHD-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK", "length": 249, "molWeight": 28530, "crc64": "CE3FD9CC9F0CE949", "md5": "6F31364E54B97F398A207D77568934D7"}}
{"primaryAccession": "Q9UPW6", "text": "This is DNA-binding protein SATB2 protein, from Human, contains 733 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UPW6", "organism_name": "Human", "protein_name": "DNA-binding protein SATB2", "length": 733, "firstPublicDate": "2001-04-27", "FUNCTION": "Binds to DNA, at nuclear matrix- or scaffold-associated regions, Thought to recognize the sugar-phosphate structure of double-stranded DNA, Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling, Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers, Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression, Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex, May play an important role in palate formation, Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CUT homeobox family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMIPVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR", "length": 733, "molWeight": 82555, "crc64": "1FE1FCBD34F11E9E", "md5": "45BE26D63833DD5D312660FF2E934CCD"}}
{"primaryAccession": "Q9UQ49", "text": "This is Sialidase-3 protein, from Human, contains 428 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UQ49", "organism_name": "Human", "protein_name": "Sialidase-3", "length": 428, "firstPublicDate": "2001-11-16", "FUNCTION": "Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides, Displays high catalytic efficiency for gangliosides including alpha-(2->3)-sialylated GD1a and GM3 and alpha-(2->8)-sialylated GD3 (PubMed:11298736, PubMed:15847605, PubMed:10861246, PubMed:20511247, PubMed:28646141, PubMed:10405317, PubMed:12011038), Plays a role in the regulation of transmembrane signaling through the modulation of ganglioside content of the lipid bilayer and by direct interaction with signaling receptors, such as EGFR (PubMed:17334392, PubMed:25922362), Desialylates EGFR and activates downstream signaling in proliferating cells (PubMed:25922362), Contributes to clathrin-mediated endocytosis by regulating sorting of endocytosed receptors to early and recycling endosomes (PubMed:26251452)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glycosyl hydrolase 33 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEEVTTCSFNSPLFRQEDDRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRRGLRIGQLVQWGPLKPLMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSGRNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYTYYIPSWFFCFQLPCKTRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVLYCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSSKDAPTIQQSSPGSSLRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRPWILHCGPCGYSDLAALEEEGLFGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSPGRNPSQFKSN", "length": 428, "molWeight": 48252, "crc64": "35D1DD9359A78C98", "md5": "C8BD5FE8C447A033F3EC1EFE836BA206"}}
{"primaryAccession": "Q9UQ84", "text": "This is Exonuclease 1 protein, from Human, contains 846 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UQ84", "organism_name": "Human", "protein_name": "Exonuclease 1", "length": 846, "firstPublicDate": "2006-01-24", "FUNCTION": "5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity, Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch, Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment, Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes, Essential for male and female meiosis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the XPG/RAD2 endonuclease family, EXO1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHNAENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRVQRAIFQ", "length": 846, "molWeight": 94103, "crc64": "850BC21CA9790D08", "md5": "89997E625CB1BCDEEFD0F14D4E6B14F4"}}
{"primaryAccession": "Q9UQY9", "text": "This is Cell cycle protein kinase spo4 protein, from Fission yeast, contains 429 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UQY9", "organism_name": "Fission yeast", "protein_name": "Cell cycle protein kinase spo4", "length": 429, "firstPublicDate": "2002-12-06", "FUNCTION": "Required for the initiation of meiosis II and progression through anaphase II", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLSMLLPFGNSGVYASDVDREDRPEIAKLVQAFPTIEEDYHVVKLVGAGSFSSVFKAVDRHFDSYDNSYWISSQIEDQMPHDKTKRPKNHFVALKRIYATVLPSRIQTELEMLHELRGSDCVLNMITAVRHQDQVLIVLPFIQHAEFRDFYMKYSLPEIGAYLRDLLKGLAHIDAKGIIHRDIKPGNFAWNPYTQRGVILDFGLAQWQEADAPTENCCVDKLRKLKQEGKYYDYFPFEKTIADPPEGYLLHDPRPTKRADRAGTRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPFFRCEDDIDAIVELAHIFGRNGMSNCALLHGQIWSDNIPTLLDQKHNWLDLIASITKNDENLILETSSDYQVALAIDLLDKLLELHPSKRVKAKTALQHEFFNACGVTRSGFEAENPFRSDFPSTVEQ", "length": 429, "molWeight": 49155, "crc64": "B0E5E4EDEA2247EB", "md5": "78F34E15D72F48A984F14E514EBB8EB0"}}
{"primaryAccession": "Q9UR19", "text": "This is Versatile peroxidase VPL1 protein, from Boletus of the steppes, contains 361 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UR19", "organism_name": "Boletus of the steppes", "protein_name": "Versatile peroxidase VPL1", "length": 361, "firstPublicDate": "2007-10-23", "FUNCTION": "A versatile ligninolytic peroxidase that combines the substrate specificity characteristics of the two other ligninolytic peroxidases, manganese peroxidase and lignin peroxidase", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peroxidase family, Ligninase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSFKTLSALALALGAAVQFASAAVPLVQKRATCADGRTTANAACCVLFPILDDIQENLFDGAQCGEEVHESLRLTFHDAIGFSPTLGGGGADGSIIAFDTIETNFPANAGIDEIVSAQKPFVAKHNISAGDFIQFAGAVGVSNCPGGVRIPFFLGRPDAVAASPDHLVPEPFDSVDSILARMSDAGFSPVEVVWLLASHSIAAADKVDPSIPGTPFDSTPGVFDSQFFIETQLKGRLFPGTADNKGEAQSPLQGEIRLQSDHLLARDPQTACEWQSMVNNQPKIQNRFAATMSKMALLGQDKTKLIDCSDVIPTPPALVGAAHLPAGFSLSDVEQACAATPFPALTADPGPVTSVPPVPGS", "length": 361, "molWeight": 37596, "crc64": "5E8297DAFD971BDE", "md5": "1FC12E68AF5D89FEBE61E72FFFC57415"}}
{"primaryAccession": "Q9URT4", "text": "This is CENP-A multicopy suppressor protein 2 protein, from Fission yeast, contains 697 amino acids, has 1 GATA-type; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [351, 378], "description": "GATA-type; atypical", "keyword_description": "Zinc finger", "textural_description": "GATA-type; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9URT4", "organism_name": "Fission yeast", "protein_name": "CENP-A multicopy suppressor protein 2", "length": 697, "firstPublicDate": "2003-05-16", "FUNCTION": "Required for proper chromosome segregation via regulation of CENP-A localization to the centromere", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"GATA-type; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMEKSLNTVTSLPLRVIYCIDRASAIRCLAKSQHAVPIQVLKEVEPKKVICQVDIQHVIQTVCRCSPELSCKSQGDFSVYFLDHTEPDELFVGLGYWSSLLLSPTLNAGTSNSDTVWVNGFIVEFGIQRSIEIKLRFQSLQNSFEVGTPETHTSSKFLSSTLPPSLIFDPSSSEKSDSISGSLFDTNYTCPVNINGLSKQKSVRELKSPSRPSALAETNVEELELDSLFHASNDISCSATSFSEPYILDHQAALDHPATDPVCSASSTTVNSAVSTKKRRRESSTISPESAYVAAQLQNPSEREQVHEFIKEQVRIARGRIEKKFTNVRGKNRIEEQLTLSLQEGKIPPYCQNCGTIKTANWRNATYMNITLMLCNACGIYWTSRRSMRPRNLWSTYKAFETEKPLENDAFAQLELAVYKLSQQRKLSISIFRELENAGRHSPLNRLTSLDSTHSAPDPNHISKPSVVNQQKSRGGPRTAKLKNDLRRIQSSPIVAPTPDTSFREPLSEIGSNDSWLVLPNSLSANIQNDVLRKTDFMCTDKENVAFPLKTTTKPMPKVNKEETEPTLPVCDSEKENDDLECYFRTPPKPTTLQKQQQSPSPWRSELFLSDPDQNVLTPRHKPKFDLSKALSSVAKSNNIENSPQLPERYDFSLELGLNSQLDNEERRDIPLMTDLVMPSSPPMVPADRHLSVENTC", "length": 697, "molWeight": 78160, "crc64": "37E68D8232C1C069", "md5": "72F12569B12B901571F1701A5EE43E96"}}
{"primaryAccession": "Q9USH8", "text": "This is Glucosidase 2 subunit beta protein, from Fission yeast, contains 506 amino acids, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9USH8", "organism_name": "Fission yeast", "protein_name": "Glucosidase 2 subunit beta", "length": 506, "firstPublicDate": "2004-03-29", "FUNCTION": "Subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins in the endoplasmic reticulum (ER), Specifically required for the cleavage of the final glucose, The subunit beta retains the catalytic subunit alpha in the ER", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKFSQWYTLTAPLLISSLYTVNAANDLRGVASDKSDLYKPDAKGNWKCLGSDKLISFNQVNDDYCDCPDGSDEPGTSACHNGKFFCKNTGYISSYIPSNRVDDTVCDCCDGSDESLIKCPNTCAQKAREYLATLEEHNRLVKNGLKIREQWALESAKKTDEVKARYKEISDSLVAVSAEKTQLSEKVEKMKRSTDLGAEAVLPLDFQDLRVALLSLVDERNEMQERLDILTNLLDELTLLYETDKFDETMKEAILSFEDLKEQEIRRKVSSDDVHNYLESCNNHLSMLTGPSEDITFSSLIKDIKKILNSLVWNIKLSLINFGILSPSASSTPLTDSESYRRFEAAQRDLDAAEENEKSLEKEHTKLMHELEYHHGWDLYRAIKGMETKREIGGYTYKVVFYENVFQDSILLGNFASQEGNVLKYENGQSCWNGPHRSAIVTVECGVENEIVSVLEAQKCEYLIKMKSPAACSPDQLKQSLLNTQNSANENAVNGMEDKESSVDEL", "length": 506, "molWeight": 57075, "crc64": "F7CA7C65B4035C56", "md5": "B454AD4C07853EEC4497D0BB043C7FC8"}}
{"primaryAccession": "Q9USP8", "text": "This is Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial protein, from Fission yeast, contains 379 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9USP8", "organism_name": "Fission yeast", "protein_name": "Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial", "length": 379, "firstPublicDate": "2001-02-21", "FUNCTION": "Performs an essential role in the oxidative function of the citric acid cycle and is involved in glutamate biosynthesis (PubMed:7903653), Also binds RNA; specifically to the 5'-untranslated leaders of mitochondrial mRNAs (PubMed:10975257)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSMLSTLRTAGSLRTFSRSACYSFQRFSSTKAAAGTYEGVKNANGNYTVTMIAGDGIGPEIAQSVERIFKAAKVPIEWERVKVYPILKNGTTTIPDDAKESVRKNKVALKGPLATPIGKGHVSMNLTLRRTFGLFANVRPCVSITGYKTPYDNVNTVLIRENTEGEYSGIEHEVIPGVVQSIKLITRAASERVIRYAFQYARQTGKNNITVVHKATIMRMADGLFLECAKELAPEYPDIELREEILDNACLKIVTDPVPYNNTVMVMPNLYGDIVSDMCAGLIGGLGLTPSGNIGNQASIFEAVHGTAPDIAGKGLANPTALLLSSVMMLKHMNLNDYAKRIESAIFDTLANNPDARTKDLGGKSNNVQYTDAIISKLK", "length": 379, "molWeight": 41188, "crc64": "AE2FB477AC36D963", "md5": "4386DCB8C7466C388E6189D2BFC29D42"}}
{"primaryAccession": "Q9UT35", "text": "This is Guanosine-diphosphatase protein, from Fission yeast, contains 556 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UT35", "organism_name": "Fission yeast", "protein_name": "Guanosine-diphosphatase", "length": 556, "firstPublicDate": "2004-04-13", "FUNCTION": "After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GDA1/CD39 NTPase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTPTMKSIARRKALLIALSIFAVTFILWNGFPGSSNRPLPSSNDEFHYEDIELPSGYRSEGEVVDLLNPKDELEEPLFSEEPLFPVTTSIPTKTAVSKPKIAPTSAAKDVTFSSSIDSDDCSVAYDNSKPVRQYVLMIDAGSTGSRVHVYQFNNCNPSPKLEEEFFKMIEPGLSSFAGDPEGAAASLDPLLDYAMENVPEEYRRCSPIAVKATAGLRLTGESEAKAILKSVRQHLENDYPFPIVKDGVSILEGSMEGIYAWITINYLLGTLGGKATHSTVAVMDLGGASTQLVFEPRFASDGESLVDGDHKYVLDYNGEQYELYQHSHLGYGLKEARKLIHKFVLNNAEALKESLELLGDSTSIIHPCLHLNASLTHPDSKSEASEVVFVGPSLAHLSLQCRGIAEKALYKDKNCPVRPCSFNGVHQPKFTETFTDSPIYLISYFYDRMISLGMPSTFTIEDMKYLANSVCSGPTYWQDAFSLTDALKELKEEPEWCLDLNYMISLLSVGYEIPNNRQLHTAKKIDNKELGWCLGASLSMLSEQNNGWNCNVKEEI", "length": 556, "molWeight": 61589, "crc64": "1D811E3D6A6BBB85", "md5": "8EFEB5C90A93EABB56D2E1E89B130FF7"}}
{"primaryAccession": "Q9UTL6", "text": "This is J-type co-chaperone jac1, mitochondrial protein, from Fission yeast, contains 225 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UTL6", "organism_name": "Fission yeast", "protein_name": "J-type co-chaperone jac1, mitochondrial", "length": 225, "firstPublicDate": "2009-02-10", "FUNCTION": "Co-chaperone required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria (PubMed:26545917), Stimulates the ATPase activity of the mitochondrial Hsp70 chaperone ssc1, to mediate the transfer of iron-sulfur clusters from isu1 to grx5 (PubMed:26545917)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the HscB family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLKQAGNQSFRPFISFAQKSLFNRQITGNHWIFARFKFYPLNKIVNYNHFHSSSCQSEAKNFYKQFEGDISDPPPKGPFDIDLGALKSSYLRKMKTLHPDVAQGKDAALAQRDSAELSKAYNTLKAPLTRAEYILQLQGINPVSEDISNSDPEFLMEIMDVHENISASRDSPEKLLQLSQENQGRKVQEINEIRKAMESSNWDSALLYVNRLRYWNTIDKILHDL", "length": 225, "molWeight": 25901, "crc64": "41F3DB1FBED9C466", "md5": "C4AB590E37DBDC742889B2FF61EF209A"}}
{"primaryAccession": "Q9UU96", "text": "This is Polynucleotide 5'-hydroxyl-kinase grc3 protein, from Fission yeast, contains 736 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UU96", "organism_name": "Fission yeast", "protein_name": "Polynucleotide 5'-hydroxyl-kinase grc3", "length": 736, "firstPublicDate": "2004-03-29", "FUNCTION": "Polynucleotide 5'-kinase required for both rRNA processing and heterochromatic gene silencing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Clp1 family, NOL9/GRC3 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVKRQRIESSNVPLSAFAVRQLTLSKAARKKDNSSGKKRSVSEEESQDKYEDEMKTEGEFPSYKHTLVQVVVPGVDHRTKLHSESSKNDSEITPDINRSKVNPQEYSEFSVASPQTISPSLPLNLDDETVSENVPHSPQSSNDAIPVIKITEENSFRVKDTLYVGLHKDQKLAMVGTFIFRSVRGKFQLFGATYSSACMSWFPLNAPLAFATPVFSAIDNALPAMQISEYEEDSLNLRSFAVPSYSPKEHEYELEPKDILPNFETVIAFRENENGLSKIARVLPFAKRLFSFKNLLQDASSISNNFEITPESWCSFSNQLLFSTSKSDYVVPRLMVCGPKGSGKSSFSRYITNRLLQQYRHIAYLDLDPGQPEVVPSGHISLYYINSPLQGPVFARMLFPTYMLRLHLGDISPQKDPDHYIACVTRLFAEYKDYIFNQEISQKEIIPLIINCPGWIRGGGAELLSSIVDICQPTEVVYMSREDMKSSHREKKSIYQHKEYMPDFLSSRDEFQLTLLESTWQYLPDPNVNKVTSADNRMLGLLSYLYFNCNLQRWDFTTSLTACQPIATAFKGSSKGIDAVNIIGEPLNVNDVAKTINGTLMALYACDTASLDNSNTQRIVSSPEGIPLIINDGLPLDPNTSHCLGLIVLRTIDLKRNEFHFVGPLNLELIKDAYAKSLKIVLERGRLELPVYAMLDHRLAQYSELPYLDRNHDRVAVGAHRRRVRRNIIRRSTFVG", "length": 736, "molWeight": 83251, "crc64": "13364A669BEB8939", "md5": "D5AAAF7D71DDABD13F46CA91693B5FD8"}}
{"primaryAccession": "Q9V3J8", "text": "This is Protein will die slowly protein, from Fruit fly, contains 361 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9V3J8", "organism_name": "Fruit fly", "protein_name": "Protein will die slowly", "length": 361, "firstPublicDate": "2000-12-01", "FUNCTION": "Contributes to histone modification, May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4' (PubMed:25310983), In neurons and together with DNA N6-methyl adenine demethylase Tet, plays a role in the maintenance of transcriptional activation for specific sets of genes (PubMed:30078725)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WD repeat WDR5/wds family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVPIGAVHGGHPGVVHPPQQPLPTAPSGPNSLQPNSVGQPGATTSSNSSASNKSSLSVKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKSDT", "length": 361, "molWeight": 39041, "crc64": "B2A64127F1E0292D", "md5": "BBA31EF4EE3304320E64E714E0C768C5"}}
{"primaryAccession": "Q9V3R8", "text": "This is UbiA prenyltransferase domain-containing protein 1 homolog protein, from Fruit fly, contains 359 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9V3R8", "organism_name": "Fruit fly", "protein_name": "UbiA prenyltransferase domain-containing protein 1 homolog", "length": 359, "firstPublicDate": "2006-06-27", "FUNCTION": "Prenyltransferase that mediates the formation of menaquinone-4 (MK-4), a vitamin K2 isoform, thereby acting as a mitochondrial electron carrier, Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4, MK-4 acts as a membrane electron carrier downstream of a electron transport chain complex, improving mitochondrial oxygen consumption", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the UbiA prenyltransferase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATSSQLLPNGNLSRNGKTKTEDGEEVEAVVGARAAGADAGVALTGRLTGHPSTSGTFMKLKTYLLALRPWSLSASLVPTLLGSALAYRSQWAEEFSLATFFLTAFTVVTVHCAGNVVNTYFDFIKGIDKQKADDRTLVDHILTKDEVVSLGAILYMAGCGGFVLLAVLSPAKMEHLALIYFGGLSSSFLYTGGIGFKYIALGDLVILILFGPISVLFAFMSQTGHLDWTTMGYAIPLALNTEAILHSNNTRDADNDRRAGIVTLAILIGRTASHVLYAMLLFAPYSLFFIFGLKYSLWFLLPLVTLPQAFQIEKRFRNEQTMHLVPRQTAKLNFFFGILYVVACCCAHQLPTFGLRRN", "length": 359, "molWeight": 39216, "crc64": "7D707D1E85CE18A3", "md5": "8B88A626ACF87AF1152C12D2BA2D7CC2"}}
{"primaryAccession": "Q9V3V7", "text": "This is Kinetochore protein Spc25 protein, from Fruit fly, contains 222 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9V3V7", "organism_name": "Fruit fly", "protein_name": "Kinetochore protein Spc25", "length": 222, "firstPublicDate": "2010-03-23", "FUNCTION": "Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis (PubMed:17895365, PubMed:17333235), Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:17895365, PubMed:17333235), Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics (PubMed:17333235), The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SPC25 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAIIMTESSYERRVKALYEKQIHMEALEAKFIKKVFKFNSNLLDVKEAASRHQRKVGKLQKVLMERREELDKRVSFIEELDRELEATKLHNLAMKDWFKQQKMLAKQRKNEIMESIHTLSKTTRTYINQEALPARVKGVTVLRGDKRDQLIPFDLKATDVEGLDSLCQHLESLNVDVAQWQQLISLAMDMAMESRAPTTPPKEADNCKSIIEIDLTSPMSHT", "length": 222, "molWeight": 25742, "crc64": "55C832D4CC75DDC0", "md5": "D4050D9CE6DAC6DFC7E36EF8BBC79019"}}
{"primaryAccession": "Q9V461", "text": "This is DNA replication licensing factor Mcm6 protein, from Fruit fly, contains 817 amino acids, has 1 C4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [152, 179], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9V461", "organism_name": "Fruit fly", "protein_name": "DNA replication licensing factor Mcm6", "length": 817, "firstPublicDate": "2006-05-02", "FUNCTION": "Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells, Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built, The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit, The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity Required for DNA replication and cell proliferation, Required for mitotic cycles, endocycles, and the special S phase associated with the amplification of chorion genes; has a role in origin unwinding or fork elongation at chorion loci", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MCM family", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDVADAQVGQLRVKDEVGIRAQKLFQDFLEEFKEDGEIKYTRPAASLESPDRCTLEVSFEDVEKYDQNLATAIIEEYYHIYPFLCQSVSNYVKDRIGLKTQKDCYVAFTEVPTRHKVRDLTTSKIGTLIRISGQVVRTHPVHPELVSGVFMCLDCQTEIRNVEQQFKFTNPTICRNPVCSNRKRFMLDVEKSLFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVVPDVSVLAGVGTRAENSSRHKPGEGMDGVTGLKALGMRELNYRMAFLACSVQATTARFGGTDLPMSEVTAEDMKKQMTDAEWHKIYEMSKDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAKTTTEKTSLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIARAGVRATLNARTSILAAANPINGRYDRSKSLQQNIQLSAPIMSRFDLFFILVDECNEVVDYAIARKIVDLHSNIEESVERAYTREEVLRYVTFARQFKPVISQEAGHMLVENYGHLRQRDTGTSGRSTWRITVRQLESMIRLSEAMAKLECSNRVLERHVKEAFRLLNKSIIRVEQPDIHLDDDEGLDMDDGIQHDIDMENNGAAANVDENNGMDTSASGAVQKKKFTLSFEDYKNLSTMLVLHMRAEEARCEVEGNDTGIKRSNVVTWYLEQVADQIESEDELISRKNLIEKLIDRLIYHDQVIIPLKTSTLKPRIQVQKDFVEEDDPLLVVHPNYVVE", "length": 817, "molWeight": 92353, "crc64": "0B7921FB3D888980", "md5": "A28E8FA20C8DB71D3647F444EC1B0246"}}
{"primaryAccession": "Q9V464", "text": "This is Histone chaperone asf1 protein, from Fruit fly, contains 218 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9V464", "organism_name": "Fruit fly", "protein_name": "Histone chaperone asf1", "length": 218, "firstPublicDate": "2007-04-17", "FUNCTION": "Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (PubMed:10591219, PubMed:12381660, PubMed:14561777, PubMed:16151251, PubMed:16396992), Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly (PubMed:11533245), Plays a role in the formation of silent heterochromatin (PubMed:12381660, PubMed:28320872)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ASF1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAKVHITNVVVLDNPSSFFNPFQFELTFECIEELKEDLEWKMIYVGSAESEEHDQVLDTIYVGPVPEGRHIFVFQADPPDVSKIPEPDAVGVTIVLLTCSYRGQEFVRVGYYVNNDYADPEMRENPPTKPLFEKLTRNILASKPRVTRFKINWDYGHINGNGNGVENGHQDEMATDGPSTSEAASAVIHPEDDNSLAMPMENGIKALNENSNSLAMEC", "length": 218, "molWeight": 24409, "crc64": "0AD5CA90118BE1C4", "md5": "434EDEFFD450E6B1FCD71CBD403147F1"}}
{"primaryAccession": "Q9V5M6", "text": "This is Longitudinals lacking protein, isoforms J/P/Q/S/Z protein, from Fruit fly, contains 963 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [849, 871], "description": "C2H2-type 1; degenerate", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 1; degenerate Zinc finger"}, {"location": [878, 901], "description": "C2H2-type 2; degenerate", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 2; degenerate Zinc finger"}], "meta_data": {"primaryAccession": "Q9V5M6", "organism_name": "Fruit fly", "protein_name": "Longitudinals lacking protein, isoforms J/P/Q/S/Z", "length": 963, "firstPublicDate": "2005-08-30", "FUNCTION": "Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems, Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type 1; degenerate Zinc finger": 1, "C2H2-type 2; degenerate Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDDDQQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDKHPIFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRTGGGVAPKPESSGHHRGGKLSGAYTLEQTKRARLATGGAMDTSGDVSGSREGSSSPSRRRRKVRRRSMENDAHDNSNSSVLQAAASNQSILQQTGAGLAVSALVTTQLSSGPAAGTSSQASSTQQQQPLTSTNVTKKTESAKLTSSTAAPASGASASAAVQQAHLHQQQAQTTSDAINTENVQAQSQGGAQGVQGDDEDIDEGSAVGGPNSATGPNPASASASAVHAGVVVKQLASVVDKSSSNHKHKIKDNSVSSVGSEMVIEPKAEYDDDAHDENVEDLTLDEEDMTMEELDQTAGTSQGGEGSSQTYATWQHDRSQDELGLMAQDAQQRDPQDEAGQNEGGESRIRVRNWLMLADKSIIGKSSDEPSDKLTQSKKSLISDAKTTNKTSTPIRPKVSTTTTSTSTAAAAAAAATIAAKQAAAAIASSNINNNNSSLTQTVTQTVTRIGSIGRTTIACITPANNGNKSSSSNCNVDAASAAALAAAGVELDSIDDTMTEVIVKIENPESMPLNDDEDDAVCNEAIEDENTFDYDLKLGSPLSWTYDAVKIENEEFEDSYLMDNDDDDDDLLTTAAATQKHAKQSNEKQMAGSMVAGAGSGGAVKKIVLSAQQQQQLLEQQQHLQHLQLQPTSQSLQIKLPAIPATITTISAPKQMMSGAGTSGSLTPNNNCTLMSNKLGLPVKGQNLDLHWSHSDDNRYRVLVQNKRTRKESLEHSADMIYNADIEKPWVCRNCNRTYKWKNSLKCHLKNECGLPPRYFCSKMCGYATNVHSNLKRHLNTKCRDREKDADDEKKPGSASGNMPVVVGVGNGTAVPVSSSNNNNNGGGSSTSSTYTLVFQNDSA", "length": 963, "molWeight": 102734, "crc64": "850960B2AFDD577C", "md5": "7691EFD0E9DD227E9EF335F43F247C7D"}}
{"primaryAccession": "Q9V637", "text": "This is Proteasome inhibitor PI31 subunit protein, from Fruit fly, contains 270 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9V637", "organism_name": "Fruit fly", "protein_name": "Proteasome inhibitor PI31 subunit", "length": 270, "firstPublicDate": "2001-09-26", "FUNCTION": "Plays an important role in the control of proteasome function, Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome, Enhances 26S proteasome function by promoting its assembly through the interaction with the assembly chaperones PSMD9 and PMSD5, Functions together with ntc to control non-apoptotic caspase activation during sperm individualization, In testis, is required for proper protein degradation and germline cell cycle progression", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the proteasome inhibitor PI31 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MESGSTAKTGDFFYGWDLLYKTVKADVSKKSDLLIALVHFLLTKHYNFRCVGVGDDKTLPEEEGSELLPDSWNDDDTKYSLRYVHDKMLYLLLGHITEGSLLINLLDINTKKVSNICVEPETLVPEVKGGITTIMPSASEIVERYRRELLDPVFTGNSREVTTQTTNSPRPIGSDPDPLRIGEPRRGGSFIPSAFEPRPFGFPDVGRGDLDPLGRGGHGNLFSFPSRPNMGPGPVPRFDPFNPLNPNRPGQGGINPDHMRPPDWNPDYYM", "length": 270, "molWeight": 30088, "crc64": "F7972E7634E80555", "md5": "0A2D630828D55A9979A9B215B42D0589"}}
{"primaryAccession": "Q9V7P1", "text": "This is U3 small nucleolar RNA-associated protein 18 homolog protein, from Fruit fly, contains 506 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9V7P1", "organism_name": "Fruit fly", "protein_name": "U3 small nucleolar RNA-associated protein 18 homolog", "length": 506, "firstPublicDate": "2001-11-16", "FUNCTION": "Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA, Regulation of cell size by ribosome synthesis is an important parameter for stem cell maintenance and function", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WD repeat UTP18 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSDESSDGLEELQSLKALYGQQEQEKPAKIKRERYIPKASQAKELNYVEVPMEKVLFGDRQRLLTNLAKSVGQKLPNDDEDEQEENPGQAKPGDKRKAAWSDSDDEDLQVGDVKKATKHTGPLNHLRKDKSYKEYLTARFQRTLNQPKWAEKKVKNEDDEDVSSDEELLRTVGFIDRKARNSDLPQKTLNFKRVKDLNRATYAEGNATSIQFHPTSTAALVAGMNGLATIYAVDGQKNERLHNMRFKKFPLACSRIAPCGTRAFFGSVKPFYYSYDLLEAKESKLKLPGAMEFMHRFEVSPCGKFIVTAGKFGAIHLLTAKTNELLHSFKQEGKVKGFTWSSDSKRILVCGSTSNVSVLNLRQNLIEHIFMDDGCIHGESIQLSPNQRLLATGSQEGVVNIYDYESIFASKAPQPEKRFMNLRTAITDLQFNHSSELLAMCSSEAPNAFKLAHFPSATVYSNFPAQNEKVGFVTSMAFSPHSSFLAFATKGKQVPLFRLKYFKGY", "length": 506, "molWeight": 56947, "crc64": "9E2C4A10FA21E5B1", "md5": "5810D85E4069DB9DAFCAA34546C35C2F"}}
{"primaryAccession": "Q9VAC8", "text": "This is Spindle assembly abnormal protein 6 homolog protein, from Fruit fly, contains 472 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VAC8", "organism_name": "Fruit fly", "protein_name": "Spindle assembly abnormal protein 6 homolog", "length": 472, "firstPublicDate": "2005-04-12", "FUNCTION": "Central scaffolding component of the centrioles ensuring their 9-fold symmetry (PubMed:17412918, PubMed:17463247, PubMed:30013109), Required for centrosome biogenesis and duplication (PubMed:17412918, PubMed:17463247, PubMed:30013109, PubMed:33704067), In ciliated neurons, required for centriole assembly but not necessary for cilium basal body and cilia function (PubMed:30013109), Required for sperm cilium basal body elongation together with Cep135 and Ana2 (PubMed:30013109)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MWPPGSEDSYSAKMDYGKSVVNILPSVEMLVNFNGEMTRSSKRSCLLYAERVDFKELLQLRLTEKSDQRRMYITTVDSASFQDLKQDQSLNVSFSGFIDNVVRMLKDCQSGKLELHLTTRDQNLSSGREVHDYYLQFVEIRSFKNLVHLSLPCRSAPLNTVLFYINSMLEASHKKQYILEQSMQQMQAEINAQRAHAERLTTENTNIREALAENTRILEEKHAAEVHQYQEKLSKINEQRSNELERNRRAISGFQAQLDKASLEKAELKSAQEQAEKRCQTLSEELSCCKARVCTLKEQNDKLHGDVANIRKHERKLEYKIEDLKQHTVELQEHIQKGNKEKANIAAELEAEKKILHTKRQALEMASEEISKANQIIVKQSQELLNLKKTIAWRTEVALQQEKAVQAKESLLSLRENELREARITIEKLREEIPQQLQSMRNFAQGLEQKYSKQILILKERLAIPTGKENRR", "length": 472, "molWeight": 54769, "crc64": "F30EB92E059BDDB0", "md5": "F086A8F18D7CDB1D9090CD3CE91FF30A"}}
{"primaryAccession": "Q9VBW9", "text": "This is Protein distal antenna-related protein, from Fruit fly, contains 419 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VBW9", "organism_name": "Fruit fly", "protein_name": "Protein distal antenna-related", "length": 419, "firstPublicDate": "2008-09-23", "FUNCTION": "Probable transcription factor with a role in the retinal determination (RD) network, Regulates ato expression and is required for normal R8 induction and differentiation, Danr appears to repress Dan expression, but Dan is required for Danr expression anterior to the morphogenetic furrow (MF), Dan and Danr lie downstream of so and require dac function for highest levels of expression, Contributes to differentiation of antenna-specific characteristics; effector gene that acts downstream of homothorax (hth), Distal-less (Dll), cut (ct) and spineless (ss) genes to control differentiation of distal antennal structures", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDISAYQHMNIRMSTRGKRPLRNLTPNDKVRAIQRIHNGETKASVSRDIGVPESTLRGWCKNEQKLRFMCRQLGPDHLGLDTPPEKRAKFELQLQLPPKFVALPPNYEELGFGALPYSPADYPVQNESLLEKLSLVEFVKKNGGLHPEGALHPGQAGVMDYSNNMLHQLNLLALLNSKLTPQTADVLVDAQPKSEDNKVIDSPAASEDYSKNNYPLLSVKNWAKDPAKRVNSANQPEQVNDKNNNALEANSSAPQALVTEQAKTPMFSDTTMPLLPAPFPNPADLAPVIAPVTPANAPPTGTDNQGAALLDWCKLFNASLNFLAFAAAAASMQPGGGGPGGPSYNPNQMASGGSEPDLETYPFNEALLKRLSPLAHSEASNESYCDSEPEDLSVRSCASKASSRSHTPDKSVGSSDAEQ", "length": 419, "molWeight": 45273, "crc64": "F266E73DBDE9FE6A", "md5": "ED0DF0C63689A35C771D37523079C7E6"}}
{"primaryAccession": "Q9VDQ7", "text": "This is Phagocyte signaling-impaired protein protein, from Fruit fly, contains 948 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VDQ7", "organism_name": "Fruit fly", "protein_name": "Phagocyte signaling-impaired protein", "length": 948, "firstPublicDate": "2008-01-15", "FUNCTION": "Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of proteins beginning with Met-Asp or Met-Glu (By similarity), Has 2 roles in the larval immune response: required both for the phagocytic degradation of internalized bacteria and for the induction of Defensin in the fat body, Within the phagocytic blood cells, has a role in detection of infection and activation of the humoral immune response", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the MDM20/NAA25 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAQQQGMDSALFERRLRPVYDNLEVGNNRKALQESEKLLRKHPNLLCARALKGLSLLRLGRYDESHGCLQTVAEEKPTDDSTLQVLSFCYREMEQLDKIVELYQHAVKQNPGNEELLAHLFISHVRVEDYKAQQAVALQLYKAQPKNAYYFWSVISVVFQGIRGPESALPEKRKIYLGLAQRMVDKHIKEGKMETEQEAFLYLHILKLQNKYQEAWEFLTGELCAKLYPGAPVSMKFELLKELGNWRELNELLQQLLDADRDRWDFYKEYIQSSFELLKLTPQGVENGDKDSLARCQEFLQRIIDSSERKKRGPYLARLELHQRMRAEQLPAEKLIGDFDEMVIEYFRLFGDKSCCTHDIALFLPSISMNQRQALASKLLLESGVTSTSLPKNKEQLQKHLCALQISRMCGSHMDLPADHLLAFYTALKLHYEHGRTTFGKKLLATEMGPSDAYALLAANVMYDLSRRENKSDHLFEALCLLQYVLRNSTSNFHVKLLSLKIYHLFGCQVGAQEMYEYLDIKQIQLDSMGYVHCQLLALGGRFSGNRNVYDATLKFFTNSYKERLEYIALTYRFCTFSKMEEFMNFKERLTNSLQYVACSVEAQICDLVSCYGNITQNLSAYVAMSIEPAEDRIAWHELSDNRDLGAIIRWDPLHEVDAAEERRESFDQEVEVLQVRSLMLRLFASFIDLYHGAGLKDSPAGAETATLELLRESWTGLFQRLRVMNYKPLAQKFLVNLLPTRLHLLLDMPYERFFDDLAQLVLDLQSGSAKLAEQCKRVGDNVIATMELCVQTINESNESNGIDGLWKRRGQQQKVAASLEMLSLYAFLLSVLNDKLQVSSKTKTKKKPVENKVDGPQPISEKERSQMLQELMRQLKHKFEACDTAIRSWKAPVLPRDLSSFMSDMSLKPEVEATLIGDVSATFKDSHELMVTELRNLLKDKIRMVAK", "length": 948, "molWeight": 109110, "crc64": "799238B481ED80ED", "md5": "95F8C87E34A015C6D85A78B03ED0BFFB"}}
{"primaryAccession": "Q9VFM9", "text": "This is Twinfilin protein, from Fruit fly, contains 343 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VFM9", "organism_name": "Fruit fly", "protein_name": "Twinfilin", "length": 343, "firstPublicDate": "2007-10-23", "FUNCTION": "Actin-binding protein involved in motile and morphological processes, Inhibits actin polymerization, likely by sequestering G-actin", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the actin-binding proteins ADF family, Twinfilin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSHQTGIRANEQLAKVFGKAKNGKFRVIKVSIENEQLSCGATAETKKDWERDYDKLIGPLLEKDVPCYILYRLDAKIPLGYSWLLISWTPDTASIRQKMVYASTKATLKTEFGSAYITEELHATTLDECTLEGYRRHKQDFAAPAPLTSREEELKELRKTEVHTEINTNTRHQTLGGINCPLSEATVAAVQDLVRGKHDYLQFRIDLEEEQIHVSRAAKVELADLPKQVPEDHARYHLFLFRHTHEGDYFESYVFVYSMPGYSCSVRERMMYSSCKAPFLDELAALGVEVVKKLEIDSGSELTEAFLQDELHPKKILHRPAFAKPKGPPNRGAKRLTRPTAED", "length": 343, "molWeight": 39070, "crc64": "A6B7046EA5BC4A86", "md5": "0DAADF0F2ADC11DB46210159F9637BE7"}}
{"primaryAccession": "Q9VFP2", "text": "This is Protein roadkill protein, from Fruit fly, contains 829 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VFP2", "organism_name": "Fruit fly", "protein_name": "Protein roadkill", "length": 829, "firstPublicDate": "2007-02-06", "FUNCTION": "Involved in segment polarity, In complex with gft/CUL3, promotes ubiquitination of ci and its subsequent degradation by the proteasome, which results in hh signaling attenuation, This regulation may be important during eye formation for proper packing of ommatidia into a hexagonal array", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Tdpoz family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFEPYVKIKKKRSVNEIYENENLEQQQHHLQQQQQQPATSDNCCCENGEPQNAPEVATATVAATSVAATSAAATVATGAAASSSSSGNCSRLQQLISTPPVLLRRSSLQQQQHQQQQHHPHTPAATATPPQQQQQQQAAPSVLQQHLGHLNYESGATAAAAATAAAAAATVATSRSGSATLAQHLATPSNILQAAFGSSNLQHILTRSAPSPSSSAISSNNCSSACAGNTHYNGGNSNSGSSSSNSNHHSNSIIASRLFGAASSSSSSSSSSASASSSSVAASSSSSSHHLHSHHSALTNSITNRINQSIRRHLNQQQHHHPLSASSSSASASPSASTSSSSSYQQSSVQQQHYNCAHPAQQQQHHHHHHSSSSSSSSSSSSSHHHHNSSSSSNSNNQQQPQQSPLCLVLLVKCPNSKEFCNAAANFCDKRLPVNECQASQTARVTSNLHASSSTMAVSRVPSPPLPEVNTPVAENWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSAGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCNKSEVRAKFKFSILNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPEDKLTIFCEVSVVADSVNISGQSNIVQFKVPECKLSEDLGNLFDNEKFSDVTLSVGGREFQAHKAILAARSDVFAAMFEHEMEERKLNRVAITDVDHEVLKEMLRFIYTGKAPNLEKMADDLLAAADKYALEKLKVMCEEALCVNLSVETAAETLILADLHSADQLKAQTIDFINTHATDVMETSGWQNMITTHSHLIAEAFRALATQQIPPIGPPRKRVKMS", "length": 829, "molWeight": 89667, "crc64": "608D32B45859280E", "md5": "C5A783D48277F6492157812D4639151C"}}
{"primaryAccession": "Q9VH19", "text": "This is Leishmanolysin-like peptidase protein, from Fruit fly, contains 683 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VH19", "organism_name": "Fruit fly", "protein_name": "Leishmanolysin-like peptidase", "length": 683, "firstPublicDate": "2007-09-11", "FUNCTION": "Essential for the coordination of mitotic progression, and also plays a role in cell migration", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the peptidase M8 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAKTPPLRPHGNMAKFLAALGICSWLLVSATAHNCQHQHPKAHEVVHGVRIQLADSEDDSAGDPARHSVRRRSVAAEQPLRILLVYDESVYRLEEEKFNLINDTVLPEAVQFWEQALMVRETKGVIRLNRKCDSTQVYVKNGHTHCIDHCKATTMCGEVQVPDAHLDVCRVCNATGQNCRIDSNTQPGEGIENADFVFYVSARQTQRCFKGLTVAYAAHCQQEAALDRPIAGHANLCPESISTKPQELQTLISTVKHEILHALGFSVSLYAFFRDDDGKPRTPRKLDTGKPYLNEKLQIHQWSNETIRKVVRENWSVRGGHVNKVVDMMVTPRVIAEVRAHFNCNKLEGAELEDQGGEGTALTHWEKRILENEAMTGTHTQSPVFSRITLALMEDSGWYRANYSMATPLTWGKGLGCAFAMRSCKDWIQYNHARGRSIHPFCSKVKQDPLQTECTDDRNSVALCNLIRHEFELPKGYQNFDSLNHVKDGEEGFYGGSVSLADHCPYIQEFTWRSKNVIVRGSHCRFTENNPRPEKNFALESYGEGAKCFDHSESMWEERSCHQTREWQHWGSGCYKYDCFDGRLHILVGNYSYKCSFPGQKLSIRIAANGWLHKGAIMCPPCHELCGAQFAAQGKQCRPGEEPDPLNKYPRDNLACGAGSEKSRSVAIITAVLLLFGLRWGFS", "length": 683, "molWeight": 76978, "crc64": "C359D526F006CD9E", "md5": "24032E138CB15F87ECAD95D8757374ED"}}
{"primaryAccession": "Q9VIP8", "text": "This is Protein valois protein, from Fruit fly, contains 367 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VIP8", "organism_name": "Fruit fly", "protein_name": "Protein valois", "length": 367, "firstPublicDate": "2005-03-01", "FUNCTION": "Involved in specific localization of cytoplasmic proteins during the formation of pole plasm, Required for synthesis and/or stability of oskar protein (osk) and localization of tudor (tud) in both the nuage and posterior pole of the oocyte, Required for normal posterior localization of osk in later stages of oogenesis and for posterior localization of the vasa (vas) protein during the entire process of pole plasm assembly, May act by regulating the complex that contains the arginine N-methyltransferase csul", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFPQRSSELYRTPVTHQPPPALELAGNLEYPNLNIADLNARLENLSPRLHDCWDSIAINDHNHLALATNRREGRQWWGMLFGYGRDQMHHMSVDSANFKLQAEHTVNIVRYAEDDFLLVALGDTRLQAWSTYSKVRDSQSPYCLFLVGESSAHPTPISQLSVFKADPRTAVSGSADSTLNVWDLSGADMVSTYRSRSSHTDKLTGLATPAASVDKFVTCDRGGCARLWDVRAAAPSSTCLYADASHVLSFTSAAWAAASELQGDNHIYLGDYDGKVHTLDIRVPRKLAETREYFDKGHVAQLLINGPHLAAMSNLPASVKVANVQAGHEFIYTHQDTHSRLTDAVWTDDSTLITIGHGRKMVTHAIK", "length": 367, "molWeight": 40608, "crc64": "320DDF4437B99517", "md5": "B7C275B3D356B912A980B553C6DB04EF"}}
{"primaryAccession": "Q9VLJ6", "text": "This is Angiotensin-converting enzyme-related protein protein, from Fruit fly, contains 630 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VLJ6", "organism_name": "Fruit fly", "protein_name": "Angiotensin-converting enzyme-related protein", "length": 630, "firstPublicDate": "2005-08-30", "FUNCTION": "May be involved in the specific maturation or degradation of a number of bioactive peptides, May have a role in the specification of heart progenitors", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGACNITVLLLVIMLWLPHGLSMGNSCSASVLEARRFFELENEQLRRRFHEEFLSGYNYNTNVTEANRQAMIEVYARNAELNKRLAQQIKSSDYVQSEDADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNYATATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLTRKASQLNGHRSYADYWVQFYEDPDFERQLDATFKQLLPFYRQLHGYVRFRLRQHYGPDVMPAEGNIPISLLGNMWGQSWNELLDLFTPYPEKPFVDVKAEMEKQGYTVQKLFELGDQFFQSLGMRALPPSFWNLSVLTRPDDRHVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHELGHIQYYLQYEQQPAVYRGAPNPGFHEAVGDVIALSVMSAKHLKAIGLIENGRLDEKSRINQLFKQALSKIVFLPFGYAVDKYRYAVFRNELDESQWNCGFWQMRSEFGGVEPPVFRTEKDFDPPAKYHIDADVEYLRYFAAHIFQFQFHKALCRKAGQYAPNNSRLTLDNCDIFGSKAAGRSLSQFLSKGNSRHWKEVLEEFTGETEMDPAALLEYFEPLYQWLKQENSRLGVPLGWGPTDKIPSDCCGTFST", "length": 630, "molWeight": 73057, "crc64": "6D9355EB57773289", "md5": "FB696FBCB636D530ED96E91FA1A4D226"}}
{"primaryAccession": "Q9VQ79", "text": "This is Putative apoptosis-inducing factor 1, mitochondrial protein, from Fruit fly, contains 739 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VQ79", "organism_name": "Fruit fly", "protein_name": "Putative apoptosis-inducing factor 1, mitochondrial", "length": 739, "firstPublicDate": "2001-04-27", "FUNCTION": "Probable NADH oxidoreductase (By similarity), Mitochondrial effector of cell death that plays roles in developmentally regulated cell death and normal mitochondrial function", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the FAD-dependent oxidoreductase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSIWGVRCLTQRFIRQAYILANRRLLGPVPQRSPPAYAPLRPAHSSLYQMVKKRTLEARTKLQANKYPNHQVCVTKPSTTPPVEEYETAVEGAGVPAYANAQFQAHSQSEPLFKVGFADVKSVCSAKDVLKSDSAKLSTSQPVLDSCKATSPCEEFKRKRKETTCQPCDEDGTAPGGGDGGDEECECRMKDLRLKCLLGALAALLAGGFLAWFMTRDTDDSEAKKAEAEEEERKRRLVAGLATSPPSSEDLPKHVPYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELWYTPNPNEDPIKDYRFKQWTGSERSLFFEPDEFFIDPEDLDDNANGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMLRDAPPSVLEKVMVYRTPDDFDRLRKLAAEKRSITIVGNGFIGSELACSLAHYSRENNGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNASIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSLGGFVVNAELEARRNLYVAGDASCFFDPLLGRRRVEHHDHSVVSGRLAGENMTGAKKPYQHQSMFWSDLGPEIGYEGIGLVDSSLPTVGVFALPSESATRVDQLSESSDSDVPETSTSSSQSSKSDAGASQDGVTCDPDEAGNYGKGVIFYLKNDKIVGILLWNLFNRIGLARTIINQNKKYDDLNEVAKLFEIHA", "length": 739, "molWeight": 81217, "crc64": "71184B1721AB93AF", "md5": "8A7826D9DB69843BF382C69023F1788C"}}
{"primaryAccession": "Q9VR35", "text": "This is Eukaryotic translation initiation factor 4E-binding protein Mextli protein, from Fruit fly, contains 653 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VR35", "organism_name": "Fruit fly", "protein_name": "Eukaryotic translation initiation factor 4E-binding protein Mextli", "length": 653, "firstPublicDate": "2016-05-11", "FUNCTION": "Plays a role in promoting translation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAHTHLGRAVKNIEAPRPLKTQSRSSLKNSYLVIEELIQLIDNVTVGLQSCNTTPESITLLLHNLRVHGPQLEAVSKDTLDRAFVVFRNASQDERLNITTRLKLLELIELRAKSWDNDDTIAYYKSKQQISNVELPSEYQYDAGVQPGAFSTSPTFGVSGGVGGVNDGAAAAAAAVFNAASAAAAAQAAAIAAVGTSNQQHMLLPPGEVIRNSGKFPKPTKIPGKTYCKDEVVIRNADSGKVMGIKGRRVHMIEELSETIISFQRVNPGAKERLVQITGPAEDKINYAKQLMEDTIRRNASPVRLEPAPAVGGSCSSLNSSNSDDAIVQPRTPTGSSLANRLSFNSAQNFMTATAAAQQISQQMHHQTHHLQHQQQQQVAAVAAAAAAAAHAQATAAAGKVLRPNQQLLMHSYSTNDASVGEYKFTVNVGQHLIKITGDCCELVRVAKLVLDDYFSSSEFLASIEAGAAFDGTSLVTTPSTPLPGAGPPQFWLPGTDSGIGLNCVVSSSANNNGEGDDEVFAEPSNGGSSTSNQNGLARSRRSHFSRKESTPETKGAREKGDLDDLAGTNSLKSNASRVSYDIEHLLYYSMSPHSWTLPTDWQKMQETAPSILRNKDLQDESQRFDGDKYLASIKTAAKRDIVAADEVETLDE", "length": 653, "molWeight": 70148, "crc64": "E0C9D54DAA811C0C", "md5": "A7739FF148E335D397268580B1656EC8"}}
{"primaryAccession": "Q9VS24", "text": "This is Protein melted protein, from Fruit fly, contains 994 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VS24", "organism_name": "Fruit fly", "protein_name": "Protein melted", "length": 994, "firstPublicDate": "2007-08-21", "FUNCTION": "Participates in fat metabolism regulation by recruiting FOXO and the TSC1-TSC2 complex to the cell membrane, which positively regulates TOR activity and negatively regulates the expression of FOXO target genes, Involved in R8 photoreceptor subtype specification, During early embryonic development, may be required for ectodermal patterning", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the MELT/VEPH family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MHELFNKVLAKRDLSRAGDLFSVPDADIVDDITEVLSEISPIISHADYVKNNNDQSVVEICVTRVLSCIRETKTAERYCAALVDLLRTCLLWNLQPSGTTKEEPPHAKIAADIISSIFLNYDKKELMKIALPVAVQFLPKGNRELSRNLASYLSLAAIDHAGLLSPHTESVMESILSGNYGLLRVLSQVYEVAPEAVTPHAPLLMPLLPQCDPQERMAVFQLYLLIVQKSPEVLESCVPQLCGSLLDSDTSSITMQILLKLSQHSPSLLVDHFEQLRLAAKTNPGTIPLCAQIMTTAGIGSKETAQQALDFVLEHLPTQALLQQEATRLCSAYPVLFTDKVLACVRQKNAALSSQQDVGNGLANKTSGGVTIVSLNSSSPSPPLKPVPVGAPAINTTIVQPASVVSATPTPPPSSASAPIASSTPVSAATPTPQHAGYTRRVKLGDSRSTGRLHPASNTHRSVTRLNVASGSVGGLHKSMTRLSNSQINQQPGGSSNGNVVVQSGATPKTPTGLSNPPVTPVPPLSNNVVITGHNRHGIPVTSGGVTVTTSPSKVRPHSQGPSTLLNSSTVLMKYSTDALNQSVGSISIPQSAAVATLPSTQTQNAVSVHHASPALPQSASNGHAKSVMKLPVNGNSEVIVSGPTTNVAPRRSDNTSRTLLNANSVMDQRMSTFEPYQIMRDPVQQFCEKNFNSIKSYMDEVSQHLPPPTRCSIEVSNEFAERRTKKVAKLHFACQIRGPHCLYSKTCFTMRTRNPKTWIHMMFLDFQVRHFVKEKCVLSTRESGISNLKNIWQILKCENRSFTELVTSQFPQVKDREILVNELRHSGFLDVFEVSKTDKSNPNCNELEYQWGCFLCNHPDKAVGFLNGSNQPMIEGQLKEKKGKWRLFRRWRTRYFTLSGAHLSCKGSSGGESIDVNQIRSVKVSRGARNIPKAFEIFTADQTLILKPKDGKNAEEWVQCLSIVVAHSQARDNPTAKTNSLPARSIGSSKPSF", "length": 994, "molWeight": 108105, "crc64": "BE3A08490E2855E9", "md5": "4CA30AE19A2489B4045CD6E32E47AA5A"}}
{"primaryAccession": "Q9VTY6", "text": "This is Ubiquitin-conjugating enzyme E2 C protein, from Fruit fly, contains 178 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VTY6", "organism_name": "Fruit fly", "protein_name": "Ubiquitin-conjugating enzyme E2 C", "length": 178, "firstPublicDate": "2009-12-15", "FUNCTION": "Catalyzes the covalent attachment of ubiquitin to other proteins, Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis, Acts by initiating polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ubiquitin-conjugating enzyme family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAQNISPEQSGGAGGGGSKHSDDSMPVKDNHAVSKRLHKELMNLMMANERGISAFPDGENIFKWVGTIAGPRNTVYSGQTYRLSLDFPNSYPYAAPVVKFLTSCFHPNVDLQGAICLDILKDKWSALYDVRTILLSIQSLLGEPNNESPLNAQAAMMWNDQKEYKKYLDAFYEKHKDT", "length": 178, "molWeight": 19832, "crc64": "7EF04EE68FEDC7AB", "md5": "31EB731C1E26CE19717E97607251B09A"}}
{"primaryAccession": "Q9W0K7", "text": "This is Protein bric-a-brac 1 protein, from Fruit fly, contains 977 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9W0K7", "organism_name": "Fruit fly", "protein_name": "Protein bric-a-brac 1", "length": 977, "firstPublicDate": "2003-03-28", "FUNCTION": "Probably acts as a transcriptional regulator, Required for the specification of the tarsal segment, Also involved in antenna development", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASAQAETNVGLASEQGPVAQRQRKGTGSGADSPKSNRSSPTQQEEKRIKSEDRTSPTGGAKDEDKESQGHAVAGGGGSSPVSSPQGRSSSVASPSSSSQQFCLRWNNYQTNLTTIFDQLLQNECFVDVTLACDGRSMKAHKMVLSACSPYFQTLLAETPCQHPIVIMRDVNWSDLKAIVEFMYRGEINVSQDQIGPLLRIAEMLKVRGLADVTHMEAATAAAAAASSERMPSSPKESTSTSRTEHDREREAEELLAFMQPEKKLRTSDWDPAELRLSPLERQQGRNVRKRRWPSADTIFNPPAPPSPLSSLIAAERMELEQKERERQRDCSLMTPPPKPPMSSGSTVGATRRLETAIHALDMPSPAATPGPLSRSSRPHSQSPQQQQAQQQGQLPLPLPLHPHHHASPAPHPSQTAGSAHHPASPAGDSRFPLGPAAAMAAARELSGLGPGPSAEPRLPPPPPHHHGGGGVGGGGVGGGGAGGVGSGGGSSLADDLEIKPGIAEMIREEERAKMMENSHAWMGATGSTLAADSYQYQLQSMWQKCWNTNQNLMHHMRFRERGPLKSWRPETMAEAIFSVLKEGLSLSQAARKYDIPYPTFVLYANRVHNMLGPSIDGGPDLRPKGRGRPQRILLGIWPDEHIKGVIKTVVFRDTKDIKDESLAAHMPPYGRHSPAFPLQDLPLSYPGASGALAGAPSSMACPNGSGPQTGVGVAGEQHMSQETAAAVAAVAHNIRQQMQMAAVPPGLFNLPPHPGVGGGVGNVPGAAGGRASISPALSSGSGPRHAPSPCGPAGLLPNLPPSMAVALHHQQQQQAAHHHMQQLHLQQQQAHLHHHQQQQQQQQQQHHQGGHQVAHKSGFGASSSSSASSSSMGQHHAPKAKSSPLRSETPRLHSPLGDLGLDMASYKREFSPSRLFAEDLAELVGASVSSSSSSAAAATAPPERSAGAASAATGADAPSSSSSGGIKVEPITTTSE", "length": 977, "molWeight": 103324, "crc64": "A7676B72A43126C5", "md5": "0E767E0DB009E0DF9A1A85478FC6D4BE"}}
{"primaryAccession": "Q9W266", "text": "This is Protein windpipe protein, from Fruit fly, contains 677 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9W266", "organism_name": "Fruit fly", "protein_name": "Protein windpipe", "length": 677, "firstPublicDate": "2015-11-11", "FUNCTION": "Plays a role in negative regulation of the JAK/STAT pathway by binding to the receptor dome and promoting its internalization for subsequent lysosomal degradation, thereby reducing JAK/STAT signaling", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MERVHLTAWLALFLIVVANATPTPARTPTGCPADCTCSLSQHTHKPLYHLKCNSTRGLRLTEKTFQSTVPVHSIDLSHLNLTRLSHLLDKLPELTSADLSHNQLKDLGHLGKGLKRLNLKHNQLTSDKLRKLPQHLQVLNLQHNNITHLPLELTHMHQLHQLELSHNAINCSCQTLEVRNWLVERIVYMEHPVVCSYPLEFRGRSWLQLKQDEICKKEKYQWFDTEENELMMGDQPAAVSAEREDEEELGKDFLPIVGNPAATAKKVRSPQIPLPSDQVEGSGDLSETNMELKLPEETVAEPEAAESQLVDAAASPSVLEEHIVKDEDEDDEGSGSGGGLLIIPDPSKVKITSEDDIDSDGKPEESDVRPLENPENSENPDTVFSNKIGIYEGDQEEKKPVEEDNIVPVVMTNLDTGLESDVVTDGPLDSSKESEDILTAKIGKPKDDSSAIYYLLAVIGLIVVGLVLFVAIKRCKYDSNAAARDAEAQRQTELLDMDKKQLGKPLHKNGHGNGQEHSPLIGEKTKLDEAQIVKKPYENGEAKDGAGQQPLLNGNGSANGGTKEAPETGEPAAHEYYPITPRYPTPQSPRASKYAQQQQLAEQNNNEPDGAYLPSSPKSGRYSPVYSPETGRVKIKLTETPKPKTPMLVTRSKSNAGDIITTPVRPIEPTHQVINGH", "length": 677, "molWeight": 74711, "crc64": "5D65987391A11B0F", "md5": "FDCE173DD0D6FAA73F7CC770A8BE7ABD"}}
{"primaryAccession": "Q9WTN6", "text": "This is Solute carrier family 22 member 21 protein, from Mouse, contains 564 amino acids, is membrane-bound, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9WTN6", "organism_name": "Mouse", "protein_name": "Solute carrier family 22 member 21", "length": 564, "firstPublicDate": "2004-07-19", "FUNCTION": "Sodium-ion independent, medium affinity carnitine transporter, Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium, Relative uptake activity ratio of carnitine to TEA is 746", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLDYDEVTAFLGEWGTFQRLIFFLLSASIIPNGFTGLSAVFLTAIPEHRCRIPDTVNLSSAWRNHSIPMETKDGPEVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQENCLDGWEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLLVQLVPSDLHYLSTTLVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILTAIITLFFPESSGVSLPETIDEMQKVKKLKQRQSLSKKGSPKESKGNVSRTSRTSEPKGF", "length": 564, "molWeight": 63321, "crc64": "C37FDCA6395DAD01", "md5": "BA76C8F2A3E08033ED3739390FCE6546"}}
{"primaryAccession": "Q9WUB6", "text": "This is Chloride channel protein ClC-Kb protein, from Mouse, contains 687 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9WUB6", "organism_name": "Mouse", "protein_name": "Chloride channel protein ClC-Kb", "length": 687, "firstPublicDate": "2004-10-11", "FUNCTION": "Voltage-gated chloride channel, Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport, May be important in urinary concentrating mechanisms, May be the basolateral chloride channel mediating net chloride absorption in CTAL cells", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the chloride channel (TC 2,A,49) family, CLCNKB subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEELVGLREGASKKPVPLQELWGPCPRIRRNIQGGLEWLKERLFRVGEDWYFLVALGVLMALISYAMNFTIGRVVRAHKWLYREIGDGHLLRYLSWTVYPVALLSFSSGFSQSITPSSGGSGIPEVKTILTGVVLEDYLDIKNFGAKVVGLSCTLATGSTIFLGKLGPFVHLSVMIAAYLGRVRTKTVGEPESKTKEMELLAAGAAVGVATVFAAPISGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFHLLAVFNNEQETITSIYKTSFPVDIPFDLPEIFFFVALGAICGILSCGYNYSQRTFLFFLKANGFTSKLLATSKPLYSALAAVVLASITYPPGVGHFMASRLSMSEHLETLFDNNSWALMTKNSSPPWAAEPDPQKLWLEWCHPQLTVFGTLVFFLVMKFWMLILATTIPIPAGYFLPIFIYGAVIGRLFGEVLSVAFPEGIVAGGRVNPIMPGAYALAGAAAFSGAVTHTLSTALLAFEVTGQLVHALPVLMAVLAANAISQSFQPSFYDGTIIVKKLPYLPWIRGRQIGSHSVTVGHFMNCALTTLAKDMPLEQVIQVVISTDVTQYPLVETTESQTLVGVVKRTHLVQALQTEPASWAPGQQPCLQDILANGCPTQPVTLQLSLETSLHETHNLFELLNLQTLFVTSRGRAVGSVSWVELKKAISTLTNPPAPK", "length": 687, "molWeight": 75009, "crc64": "BEF5A605DB3A3025", "md5": "507EC43D3753C123D86CCF6C59FCA85D"}}
{"primaryAccession": "Q9WUI0", "text": "This is Homeobox protein MIXL1 protein, from Mouse, contains 231 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9WUI0", "organism_name": "Mouse", "protein_name": "Homeobox protein MIXL1", "length": 231, "firstPublicDate": "2007-11-13", "FUNCTION": "Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation, Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages, Also involved in the morphogenesis of the heart and the gut during embryogenesis, Acts as a negative regulator of brachyury expression", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the paired homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAAGSQQLQFAEGAAFPIFPAAHPGGQLLPAMRPASGLPAAPHDSRAPAATQCFPNRDSSPTAQTPAGLDPPGPSKGSAAPSAPQRRKRTSFSSEQLQLLELVFRQTMYPDIHLRERLAALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLSSRRGVFLHCPAPGTEARCLKPQLPLEADVNHVPDPSMTGGGVCTSGSQSFETYSSLSEDIGSKLDSWEEHIFSALGNF", "length": 231, "molWeight": 24844, "crc64": "59DA80A5E7E6EE33", "md5": "ED9AE9614D9F72516D19571E8BB7C40C"}}
{"primaryAccession": "Q9WUP1", "text": "This is Receptor activity-modifying protein 3 protein, from Mouse, contains 147 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9WUP1", "organism_name": "Mouse", "protein_name": "Receptor activity-modifying protein 3", "length": 147, "firstPublicDate": "2003-01-10", "FUNCTION": "Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner, Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane, Acts as a receptor for adrenomedullin (AM) together with CALCRL", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the RAMP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKTPAQRLHLLPLLLLLCGECAQVCGCNETGMLERLPRCGKAFADMMQKVAVWKWCNLSEFIVYYESFTNCTEMETNIMGCYWPNPLAQSFITGIHRQFFSNCTVDRTHWEDPPDEVLIPLIAVPVVLTVAMAGLVVWRSKHTDRLL", "length": 147, "molWeight": 16779, "crc64": "359EE741034C34E8", "md5": "FC7031DAF704C0EC027829EAB5A8710D"}}
{"primaryAccession": "Q9XEE9", "text": "This is GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase protein, from Mouse-ear cress, contains 463 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XEE9", "organism_name": "Mouse-ear cress", "protein_name": "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase", "length": 463, "firstPublicDate": "2011-09-21", "FUNCTION": "Required for N-linked oligosaccharide assembly, Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyltransferase 4 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAIYFILYTLLTIIFAVSLSLFLSVINARKSRKRAVGFFHPYTNDGGGGERVLWCAVKAIQEENPDLDCVIFTGDHDSSSDSLARRAVDRFGVHLQSPPKVIHLNKRKWIEESTYPHFTMIGQSLGSVYLAWEALRMFTPLYFLDTSGYAFTYPLARIFGCKVVCYTHYPTISLDMISRVRQRNSMYNNDASIAKSNWLSTCKLVYYRAFSWMYGMVGSCTHLAMVNSSWTKSHIEVLWRIPERITRVYPPCDTSGLQAFPLERSSDPPKIISVAQFRPEKAHMLQLEAFSLALEKLDADVPRPKLQFVGSCRNNSDEERLQKLKDRAVELKVDGDVQFYKNAMYRELVELLGNAVAGLHGMIDEHFGISVVEYMAAGAIPIAHNSAGPKMDIVLEEDGQKTGFLAETVEEYAEAILEIVKMNETERLKMAESARKRAARFSEQRFCEDFKTAIRPIFTGPLK", "length": 463, "molWeight": 52573, "crc64": "7092C34149CD4AE1", "md5": "49264910E49FBD84FBD213EC9DB73345"}}
{"primaryAccession": "Q9XF04", "text": "This is Protein CLAVATA 3 protein, from Mouse-ear cress, contains 96 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XF04", "organism_name": "Mouse-ear cress", "protein_name": "Protein CLAVATA 3", "length": 96, "firstPublicDate": "2001-01-24", "FUNCTION": "The secreted peptide MCLV3 activates a signal transduction cascade to restrict WUSCHEL (WUS) expression, inducing shoot and root meristem consumption as cells differentiated into other organs", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the CLV3/ESR signal peptide family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDSKSFLLLLLLFCFLFLHDASDLTQAHAHVQGLSNRKMMMMKMESEWVGANGEAEKAKTKGLGLHEELRTVPSGPDPLHHHVNPPRQPRNNFQLP", "length": 96, "molWeight": 10871, "crc64": "4F175F5CE2558DD5", "md5": "9D93F0D9CC64B40828131B1DEF5CBBB7"}}
{"primaryAccession": "Q9XGM8", "text": "This is Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase protein, from Mouse-ear cress, contains 444 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XGM8", "organism_name": "Mouse-ear cress", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "length": 444, "firstPublicDate": "2008-12-16", "FUNCTION": "Initiates complex N-linked carbohydrate formation, Essential for the conversion of high-mannose to hybrid and complex N-glycans, Required for normal root growth and morphology", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the glycosyltransferase 13 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MARISCDLRFLLIPAAFMFIYIQMRLFQTQSQYADRLSSAIESENHCTSQMRGLIDEVSIKQSRIVALEDMKNRQDEELVQLKDLIQTFEKKGIAKLTQGGQMPVAAVVVMACSRADYLERTVKSVLTYQTPVASKYPLFISQDGSDQAVKSKSLSYNQLTYMQHLDFEPVVTERPGELTAYYKIARHYKWALDQLFYKHKFSRVIILEDDMEIAPDFFDYFEAAASLMDRDKTIMAASSWNDNGQKQFVHDPYALYRSDFFPGLGWMLKRSTWDELSPKWPKAYWDDWLRLKENHKGRQFIRPEVCRTYNFGEHGSSLGQFFSQYLEPIKLNDVTVDWKAKDLGYLTEGNYTKYFSGLVRQARPIQGSDLVLKAQNIKDDVRIRYKDQVEFERIAGEFGIFEEWKDGVPRTAYKGVVVFRIQTTRRVFLVGPDSVMQLGIRNS", "length": 444, "molWeight": 51634, "crc64": "B3DDCF221C526336", "md5": "43E1C0EB5093FA85DEB5297CF399F456"}}
{"primaryAccession": "Q9XI84", "text": "This is [Fructose-bisphosphate aldolase]-lysine N-methyltransferase, chloroplastic protein, from Mouse-ear cress, contains 482 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XI84", "organism_name": "Mouse-ear cress", "protein_name": "[Fructose-bisphosphate aldolase]-lysine N-methyltransferase, chloroplastic", "length": 482, "firstPublicDate": "2001-10-24", "FUNCTION": "Protein-lysine methyltransferase methylating chloroplastic fructose 1,6-bisphosphate aldolases, Can also use with low efficiency gamma-tocopherol methyltransferase as substrate, but not a cytosolic aldolase, Able to interact with unmethylated Rubisco, but unlike in pea, the complex is catalytically unproductive", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the class V-like SAM-binding methyltransferase superfamily, Plant protein-lysine LSMT methyltransferase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSASVAVVSGFLRIPSIQKSQNPSFLFSRPKKSLVRPISASSSELPENVRNFWKWLRDQGVVSGKSVAEPAVVPEGLGLVARRDIGRNEVVLEIPKRLWINPETVTASKIGPLCGGLKPWVSVALFLIREKYEEESSWRVYLDMLPQSTDSTVFWSEEELAELKGTQLLSTTLGVKEYVENEFLKLEQEILLPNKDLFSSRITLDDFIWAFGILKSRAFSRLRGQNLVLIPLADLINHNPAIKTEDYAYEIKGAGLFSRDLLFSLKSPVYVKAGEQVYIQYDLNKSNAELALDYGFVESNPKRNSYTLTIEIPESDPFFGDKLDIAESNKMGETGYFDIVDGQTLPAGMLQYLRLVALGGPDAFLLESIFNNTIWGHLELPVSRTNEELICRVVRDACKSALSGFDTTIEEDEKLLDKGKLEPRLEMALKIRIGEKRVLQQIDQIFKDRELELDILEYYQERRLKDLGLVGEQGDIIFWETK", "length": 482, "molWeight": 54612, "crc64": "9E93472B5B14EFC6", "md5": "2B74885A9699F38E8DC14924186BD4BB"}}
{"primaryAccession": "Q9XI90", "text": "This is Probable WRKY transcription factor 4 protein, from Mouse-ear cress, contains 514 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XI90", "organism_name": "Mouse-ear cress", "protein_name": "Probable WRKY transcription factor 4", "length": 514, "firstPublicDate": "2002-05-15", "FUNCTION": "Transcription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element, Has a positive role in resistance to necrotrophic pathogens (e,g, Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e,g, Pseudomonas syringae)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSEKEEAPSTSKSTGAPSRPTLSLPPRPFSEMFFNGGVGFSPGPMTLVSNMFPDSDEFRSFSQLLAGAMSSPATAAAAAAAATASDYQRLGEGTNSSSGDVDPRFKQNRPTGLMISQSQSPSMFTVPPGLSPAMLLDSPSFLGLFSPVQGSYGMTHQQALAQVTAQAVQANANMQPQTEYPPPSQVQSFSSGQAQIPTSAPLPAQRETSDVTIIEHRSQQPLNVDKPADDGYNWRKYGQKQVKGSEFPRSYYKCTNPGCPVKKKVERSLDGQVTEIIYKGQHNHEPPQNTKRGNKDNTANINGSSINNNRGSSELGASQFQTNSSNKTKREQHEAVSQATTTEHLSEASDGEEVGNGETDVREKDENEPDPKRRSTEVRISEPAPAASHRTVTEPRIIVQTTSEVDLLDDGYRWRKYGQKVVKGNPYPRSYYKCTTPGCGVRKHVERAATDPKAVVTTYEGKHNHDLPAAKSSSHAAAAAQLRPDNRPGGLANLNQQQQQQPVARLRLKEEQTT", "length": 514, "molWeight": 55816, "crc64": "01010F8745C420C5", "md5": "7F24F9FF0AD95F529DA26E19383B7A3D"}}
{"primaryAccession": "Q9XTF3", "text": "This is Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 protein, from Caenorhabditis elegans, contains 817 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XTF3", "organism_name": "Caenorhabditis elegans", "protein_name": "Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2", "length": 817, "firstPublicDate": "2010-01-19", "FUNCTION": "Required for oocyte-to-zygote transition in which it phosphorylates oocyte proteins, including mei-1, oma-1, oma-2, mex-5, and mex-6, modifying their activity and/or stability following meiosis (PubMed:16289132, PubMed:16338136, PubMed:17869113, PubMed:18854162, PubMed:18199581, PubMed:19879842), Through phosphorylation of P granule components including meg-1, promotes the disassembly of zygotic P granules in the anterior cytoplasm during zygote polarization, and thus plays a role in P granule distribution and segregation in early stage embryos following meiosis (PubMed:25535836), Functions in both spindle positioning and in the posterior localization of cytoplasmic determinants, including pie-1, pos-1, and pgl-1, in early embryos (PubMed:14697358), Involved in the asymmetric distribution of plk-1 at the 2-cell embryonic stage (PubMed:18199581)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAALASFTRNSRSYGQQPIDVTQQGQRDRSVMSLDAQGRSVSHECPTSTTLVRQLYLPQIPQSASFAAAPTSFSGASSSSSNHHHPVYHSQNSLPPNLLGSSQNSASSNSLVQGHRNPALGSGNTLTRSYHQPSSTNSSTNNLYGPLGTISRDLKQSIRDISPPVINSSANPHLVNYVQTSSFDNGSYEFPSGQAQQQRRLGGSQQHLAPLQQTASSLYSNPQSSSSQLLGQQQAVRPNYAYQQSLPRQQHINSHQTQAFFGTVRGPTNSTNIVTPLRASKTMIDVLAPVRDTVAAQATGLPNVGTSSSNGSSNSSSGVGSGGSGSLMTQSIGGPNKHLSASHSTLNTASTHDMMHSKIPKSPSNESLSRSHTSSSGGSQGGHNSNSGSNSGFRPEDAVQTFGAKLVPFEKNEIYNYTRVFFVGSHAKKQAGVIGGANNGGYDDENGSYQLVVHDHIAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQADEEIRILDHLRRQDSDGTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLGMPPPKSLETAKRARTFITSKGYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMGDELFVDFLKRCLDWDPETRMTPAQALKHKWLRRRLPNPPRDGLESMGGLADHEKKTETLPNIDSNANILMRKKF", "length": 817, "molWeight": 89885, "crc64": "74903C85CB68C428", "md5": "B1E2A30773F949EF21D9C1B2786BA27C"}}
{"primaryAccession": "Q9XXV8", "text": "This is Myosin-K heavy chain protein, from Social amoeba, contains 858 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XXV8", "organism_name": "Social amoeba", "protein_name": "Myosin-K heavy chain", "length": 858, "firstPublicDate": "2008-04-08", "FUNCTION": "Myosins are actin-based motor molecules with ATPase activity, Involved in phagocytosis and motility, and in the maintenance and dynamics of cell cortex", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TRAFAC class myosin-kinesin ATPase superfamily, Myosin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFRLFSSGVDDLVLVSNPSNGEVTSQIGARFDRELIYTNIGEVLIAVNPYKALPITGPEFIKLYQNASGSDASPHIYALAERAYRRMVDENESQCVIISGESGAGKTVSAKLILQYVTSVSPNNSSGGGIGGSGGGNGGIPQYDGGSDDRPSPPMGRGMGMPGMVGRGGLPTRGGGPPSRGGGPPPTRGRGGPPPPIPQNRGAPPPVSNGGAPPPVARGPVAPPPTRGAPPTRGGGPANRGGRGGGPPPVSTSRGGGGYGGSSKTVDVEHIKKVILDSNPLMEAIGNAKTVRNDNSSRFGKYLEIQFDDNNAPVGGLISTFLLEKTRVTFQQKNERNFHIFYQMLGGLDQTTKSEWGLTQATDFYYLAQSKCTTVEDVDDGKDFHEVKAAMETVGISRDEQTEIFRILAAILHVGNIRFQGEAPASVIDETPLQWAASLLGCDPTFLCQSLNHRQIQSGSARHTQYQVPQNPDQSAGLRDALAKTLYERIFDFIVARVNKAMSFSGNCKVIGVLDIYGFEVFERNSFEQFCINYVNERLQQIFIDLTVRGEQREYHEEGMKWKDISFFDNKIVVDLIDGNKPPGIMRVLDDVCKTVHAVDSAAADIKFMEKLIHSIQSHPHLVISNTGSSADEFTIKHYAGEVSYSIEEFCFKNNDNLYASIVGCLQNSTYQFIVSLFPENIQDNKQAPTTSSFKIRQSSSYLVTRLSACTPHYIRCIKPNDKKQPMNFVSSRVEHQVKYLGILENIKVKRSGYAYRQLKDIFLNRFGKIMDVQPRNVQEFVEYITRTHKDINADEFEEGKTKIFVKNPETIFVMEDLLMQKIDPIGYKNRVQAYKENEKLAQMKQGKHSMKQKCLIQ", "length": 858, "molWeight": 94364, "crc64": "E459F2AFDC9C2C1E", "md5": "B031AA4A5A86DB5A3AB622165EA62440"}}
{"primaryAccession": "Q9XZS8", "text": "This is Activating transcription factor 3 protein, from Fruit fly, contains 613 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XZS8", "organism_name": "Fruit fly", "protein_name": "Activating transcription factor 3", "length": 613, "firstPublicDate": "2016-05-11", "FUNCTION": "Transcription factor which binds to the cAMP response element (CRE) (PubMed:20023169), Regulates metabolic and innate immune homeostasis, possibly by controlling appropriate expression of genes involved in peritrophic matrix composition and ensuring the normal digestive and immune function of the gut (PubMed:22851689), Required for the expression of odorant receptors Or43b and Or47b (PubMed:26848073)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family, ATF subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFNSNIPASSLLSIDSGGLLMGGHTPKTPEILNSLIAMTNPLENFSYSSAAAAAAAVSVASSSASCSAASTPVVTVRHFNGHPNGQSHSQDSSHSSCSGSPLDSPAGTATTPSVQQTCSRLIKEGLKLSIQSKRKLSTCDSSSGSEQPHSKYSRRSSNHNGHSGSSNNYSGSMSNANDLDDDCEESSDDDSETKSQPKGLTPEDEDRRRRRRERNKIAATKCRMKKRERTQNLIKESEVLDTQNVELKNQVRQLETERQKLVDMLKSHGCQRAGGCQLPSQLLQSPAQKYLSELELETVSIDGPNSGNNNQRLQSIPSMATFKYGSKTAAAMAQQLPNGYCKPSPSAQEFEHAGYQQQQQQQQQQQPQSLNPAGNNVIDQQHANPSPSLLSDYVPNCDGLTGSASNHPSHNNNNNNNNSSGASSNTSNNNSNISSHSSNATSSTTPTATSSAIEFVKNELVDSQSPYTTALSAERFLFEPSDGFPDIKHACVLPSPCGINGLNMASVVNTNGSTGNNNNSHHNNNNNNNNHLMDFHQGLQHGNIGTGVGVGVGVGVGVGVGVGVMTPYDDEQLLLLKNGCFATDLLSQLVEEGGEYVDLDSATAFMNNGSCLA", "length": 613, "molWeight": 65161, "crc64": "C321092F06C7BD7C", "md5": "C4B3FBA4BCDEBE0F89532C539BA0A3BD"}}
{"primaryAccession": "Q9Y117", "text": "This is Polypeptide N-acetylgalactosaminyltransferase 3 protein, from Fruit fly, contains 667 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y117", "organism_name": "Fruit fly", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 3", "length": 667, "firstPublicDate": "2004-08-16", "FUNCTION": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:12829714), It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties, Prefers EA2 as substrate, Has weak activity toward Muc5AC-3, -13 and -3/13 substrates (PubMed:12829714), Plays a critical role in the regulation of integrin-mediated cell adhesion during wing development by influencing, via glycosylation, the secretion and localization of the integrin ligand Tig to the basal cell layer interface (PubMed:18835818, PubMed:20371600, PubMed:20807760, PubMed:22157008), Might have a role in protein O-glycosylation in the Golgi and thereby in establishing and/or maintaining a proper secretory apparatus structure (PubMed:20807760), Together with Pgant35A, regulates integrin levels and activity-dependent integrin signaling at the synapse in neurons and muscles (PubMed:25253852)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the glycosyltransferase 2 family, GalNAc-T subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGLRFQQLKKLWLLYLFLLFFAFFMFAISINLYVASIQGGDAEMRHPKPPPKRRSLWPHKNIVAHYIGKGDIFGNMTADDYNINLFQPINGEGADGRPVVVPPRDRFRMQRFFRLNSFNLLASDRIPLNRTLKDYRTPECRDKKYASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILVDDASDRSYLKRQLESYVKVLAVPTRIFRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEPLLSRIKESRKVVICPVIDIISDDNFSYTKTFENHWGAFNWQLSFRWFSSDRKRQTAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMDDWQYFIMLYTSGLTLGAKDKVNVTERVALRERLQCKPFSWYLENIWPEHFFPAPDRFFGKIIWLDGETECAQAYSKHMKNLPGRALSREWKRAFEEIDSKAEELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQSMDMFVITPKGQIMTNDNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQCASDSSQLWTYDMDTQQISHRDTKLCLTLKAATNSRLQKVEKVVLSMECDFKDITQKWGFIPLPWRM", "length": 667, "molWeight": 76807, "crc64": "B8C6924AA8E19805", "md5": "7BFDD4DB9F17B45E4E8279DAEEDEC645"}}
{"primaryAccession": "Q9Y216", "text": "This is Myotubularin-related protein 7 protein, from Human, contains 660 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y216", "organism_name": "Human", "protein_name": "Myotubularin-related protein 7", "length": 660, "firstPublicDate": "2000-12-01", "FUNCTION": "Phosphatase that specifically dephosphorylates phosphatidylinositol 3-phosphate (PtdIns(3)P) and inositol 1,3-bisphosphate (Ins(1,3)P2)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEHIRTPKVENVRLVDRVSPKKAALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEKQATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYEELYCFSFNPMLDKEEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEERLEKIQKVQLNCTKVKSKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEAVFLTA", "length": 660, "molWeight": 75833, "crc64": "05374B19BB500580", "md5": "9031CC35EBE63B74D8431DE5A1588A47"}}
{"primaryAccession": "Q9Y241", "text": "This is HIG1 domain family member 1A, mitochondrial protein, from Human, contains 93 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y241", "organism_name": "Human", "protein_name": "HIG1 domain family member 1A, mitochondrial", "length": 93, "firstPublicDate": "2005-09-27", "FUNCTION": "Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water, May play a role in the assembly of respiratory supercomplexes", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSTDTGVSLPSYEEDQGSKLIRKAKEAPFVPVGIAGFAAIVAYGLYKLKSRGNTKMSIHLIHMRVAAQGFVVGAMTVGMGYSMYREFWAKPKP", "length": 93, "molWeight": 10143, "crc64": "9399D8D1D381B66B", "md5": "9BA4608230F32037DF66842A5AFB6424"}}
{"primaryAccession": "Q9Y294", "text": "This is Histone chaperone ASF1A protein, from Human, contains 204 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y294", "organism_name": "Human", "protein_name": "Histone chaperone ASF1A", "length": 204, "firstPublicDate": "2007-04-17", "FUNCTION": "Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (PubMed:10759893, PubMed:11897662, PubMed:12842904, PubMed:14718166, PubMed:15664198, PubMed:16151251, PubMed:21454524), Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly (PubMed:11897662, PubMed:14718166, PubMed:15664198), Promotes homologous recombination-mediated repair of double-strand breaks (DSBs) at stalled or collapsed replication forks: acts by mediating histone replacement at DSBs, leading to recruitment of the MMS22L-TONSL complex and subsequent loading of RAD51 (PubMed:29478807), Also involved in the nuclear import of the histone H3-H4 dimer together with importin-4 (IPO4): specifically recognizes and binds newly synthesized histones with the monomethylation of H3 'Lys-9' and acetylation at 'Lys-14' (H3K9me1K14ac) marks, and diacetylation at 'Lys-5' and 'Lys-12' of H4 (H4K5K12ac) marks in the cytosol (PubMed:21454524, PubMed:29408485), Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit (PubMed:15621527)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ASF1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAESEEYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCTYRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFHINWEDNTEKLEDAESSNPNLQSLLSTDALPSASKGWSTSENSLNVMLESHMDCM", "length": 204, "molWeight": 22969, "crc64": "9819D531D3A9FC68", "md5": "E6727D155E947B7FE91115F4C02993EF"}}
{"primaryAccession": "Q9Y2J8", "text": "This is Protein-arginine deiminase type-2 protein, from Human, contains 665 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y2J8", "organism_name": "Human", "protein_name": "Protein-arginine deiminase type-2", "length": 665, "firstPublicDate": "2000-05-30", "FUNCTION": "Catalyzes the deimination of arginine residues of proteins", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein arginine deiminase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLRERTVRLQYGSRVEAVYVLGTYLWTDVYSAAPAGAQTFSLKHSEHVWVEVVRDGEAEEVATNGKQRWLLSPSTTLRVTMSQASTEASSDKVTVNYYDEEGSIPIDQAGLFLTAIEISLDVDADRDGVVEKNNPKKASWTWGPEGQGAILLVNCDRETPWLPKEDCRDEKVYSKEDLKDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRRKLYHVVKYTGGSAELLFFVEGLCFPDEGFSGLVSIHVSLLEYMAQDIPLTPIFTDTVIFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYLNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPVKELLGPDFGYVTREPLFESVTSLDSFGNLEVSPPVTVNGKTYPLGRILIGSSFPLSGGRRMTKVVRDFLKAQQVQAPVELYSDWLTVGHVDEFMSFVPIPGTKKFLLLMASTSACYKLFREKQKDGHGEAIMFKGLGGMSSKRITINKILSNESLVQENLYFQRCLDWNRDILKKELGLTEQDIIDLPALFKMDEDHRARAFFPNMVNMIVLDKDLGIPKPFGPQVEEECCLEMHVRGLLEPLGLECTFIDDISAYHKFLGEVHCGTNVRRKPFTFKWWHMVP", "length": 665, "molWeight": 75564, "crc64": "8D417A87A02D6839", "md5": "23FCF218C7C7B39B8EE42F21FBDF41D1"}}
{"primaryAccession": "Q9Y2K1", "text": "This is Zinc finger and BTB domain-containing protein 1 protein, from Human, contains 713 amino acids, has 1 C2H2-type 1; atypical Zinc finger, has 1 C2H2-type 2; atypical Zinc finger, has 1 UBZ-type Zinc finger, has 5 C2H2-type Zinc finger, is soluble, locates in Nucleus.", "functionDomainRange": [{"location": [216, 242], "description": "C2H2-type 1; atypical", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 1; atypical Zinc finger"}, {"location": [448, 470], "description": "C2H2-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 2; atypical Zinc finger"}, {"location": [533, 558], "description": "UBZ-type", "keyword_description": "Zinc finger", "textural_description": "UBZ-type Zinc finger"}, {"location": [578, 600], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [606, 628], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [634, 656], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [662, 684], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [686, 709], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9Y2K1", "organism_name": "Human", "protein_name": "Zinc finger and BTB domain-containing protein 1", "length": 713, "firstPublicDate": "2003-04-30", "FUNCTION": "Acts as a transcriptional repressor (PubMed:20797634), Represses cAMP-responsive element (CRE)-mediated transcriptional activation (PubMed:21706167), In addition, has a role in translesion DNA synthesis, Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis (PubMed:24657165), Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type 1; atypical Zinc finger": 1, "C2H2-type 2; atypical Zinc finger": 1, "UBZ-type Zinc finger": 1, "C2H2-type Zinc finger": 5}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESLQLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTGSRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDELEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAENASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSAGETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT", "length": 713, "molWeight": 82016, "crc64": "4B120DD45FA14305", "md5": "0E51AEBFDF4C3AD1CB511151716BB88B"}}
{"primaryAccession": "Q9Y2M2", "text": "This is Protein SSUH2 homolog protein, from Human, contains 375 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y2M2", "organism_name": "Human", "protein_name": "Protein SSUH2 homolog", "length": 375, "firstPublicDate": "2006-11-28", "FUNCTION": "Plays a role in odontogenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDRDLNEDDSVVDLSFEAESPLAPPTELLERLPSYDWLLQGGRGQIFFPPLEAPGRPQEQRSWPSFLEHRVPAMTEEVAREALLSFVDSKCCYSSTVAGDLVIQELKRQTLCRYRLETFSESRISEWTFQPFTNHSVDGPQRGASPRLWDIKVQGPPMFQEDTRKFQVPHSSLVKECHKCHGRGRYKCSGCHGAGTVRCPSCCGAKRKAKQSRRCQLCAGSGRRRCSTCSGRGNKTCATCKGEKKLLHFIQLVIMWKNSLFEFVSEHRLNCPRELLAKAKGENLFKDENSVVYPIVDFPLRDISLASQRGIAEHSAALASRARVLQQRQTIELIPLTEVHYWYQGKTYVYYIYGTDHQVYAVDYPERYCCGCTIV", "length": 375, "molWeight": 42732, "crc64": "D5B84353A89786CC", "md5": "A51A3F9040FA14684187E74523B2E6CC"}}
{"primaryAccession": "Q9Y2R0", "text": "This is Cytochrome c oxidase assembly factor 3 homolog, mitochondrial protein, from Human, contains 106 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y2R0", "organism_name": "Human", "protein_name": "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial", "length": 106, "firstPublicDate": "2006-06-13", "FUNCTION": "Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly, MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion, Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the COA3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASSGAGDPLDSKRGEAPFAQRIDPTREKLTPEQLHSMRQAELAQWQKVLPRRRTRNIVTGLGIGALVLAIYGYTFYSISQERFLDELEDEAKAARARALARASGS", "length": 106, "molWeight": 11731, "crc64": "ED6E73527E9B6C3C", "md5": "CE0F27EDB4ED5863FBA67A5C6130C945"}}
{"primaryAccession": "Q9Y2W1", "text": "This is Thyroid hormone receptor-associated protein 3 protein, from Human, contains 955 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y2W1", "organism_name": "Human", "protein_name": "Thyroid hormone receptor-associated protein 3", "length": 955, "firstPublicDate": "2003-02-28", "FUNCTION": "Involved in pre-mRNA splicing, Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC), Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC) recognition, May be involved in nuclear mRNA decay, Involved in regulation of signal-induced alternative splicing, During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells, Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA, Involved in response to DNA damage, Is excluced from DNA damage sites in a manner that parallels transcription inhibition; the function may involve the SNARP complex, Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex; however, it is not regarded as a stable Mediator complex subunit, Cooperatively with HELZ2, enhances the transcriptional activation mediated by PPARG, maybe through the stabilization of the PPARG binding to DNA in presence of ligand, May play a role in the terminal stage of adipocyte differentiation, Plays a role in the positive regulation of the circadian clock, Acts as a coactivator of the CLOCK-BMAL1 heterodimer and promotes its transcriptional activator activity and binding to circadian target genes (PubMed:24043798)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the BCLAF1/THRAP3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDNIQPTTE", "length": 955, "molWeight": 108666, "crc64": "01131D2479B8C0F4", "md5": "362E54332494A2D4F63C03930512FF10"}}
{"primaryAccession": "Q9Y2X7", "text": "This is ARF GTPase-activating protein GIT1 protein, from Human, contains 761 amino acids, has 1 C4-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [11, 34], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9Y2X7", "organism_name": "Human", "protein_name": "ARF GTPase-activating protein GIT1", "length": 761, "firstPublicDate": "2001-10-18", "FUNCTION": "GTPase-activating protein for ADP ribosylation factor family members, including ARF1, Multidomain scaffold protein that interacts with numerous proteins and therefore participates in many cellular functions, including receptor internalization, focal adhesion remodeling, and signaling by both G protein-coupled receptors and tyrosine kinase receptors (By similarity), Through PAK1 activation, positively regulates microtubule nucleation during interphase (PubMed:27012601), Plays a role in the regulation of cytokinesis; for this function, may act in a pathway also involving ENTR1 and PTPN13 (PubMed:23108400), May promote cell motility both by regulating focal complex dynamics and by local activation of RAC1 (PubMed:10938112, PubMed:11896197), May act as scaffold for MAPK1/3 signal transduction in focal adhesions, Recruits MAPK1/3/ERK1/2 to focal adhesions after EGF stimulation via a Src-dependent pathway, hence stimulating cell migration (PubMed:15923189), Plays a role in brain development and function, Involved in the regulation of spine density and synaptic plasticity that is required for processes involved in learning (By similarity), Plays an important role in dendritic spine morphogenesis and synapse formation (PubMed:12695502, PubMed:15800193), In hippocampal neurons, recruits guanine nucleotide exchange factors (GEFs), such as ARHGEF7/beta-PIX, to the synaptic membrane, These in turn locally activate RAC1, which is an essential step for spine morphogenesis and synapse formation (PubMed:12695502), May contribute to the organization of presynaptic active zones through oligomerization and formation of a Piccolo/PCLO-based protein network, which includes ARHGEF7/beta-PIX and FAK1 (By similarity), In neurons, through its interaction with liprin-alpha family members, may be required for AMPA receptor (GRIA2/3) proper targeting to the cell membrane (By similarity), In complex with GABA(A) receptors and ARHGEF7, plays a crucial role in regulating GABA(A) receptor synaptic stability, maintaining GPHN/gephyrin scaffolds and hence GABAergic inhibitory synaptic transmission, by locally coordinating RAC1 and PAK1 downstream effector activity, leading to F-actin stabilization (PubMed:25284783), May also be important for RAC1 downstream signaling pathway through PAK3 and regulation of neuronal inhibitory transmission at presynaptic input (By similarity), Required for successful bone regeneration during fracture healing (By similarity), The function in intramembranous ossification may, at least partly, exerted by macrophages in which GIT1 is a key negative regulator of redox homeostasis, IL1B production, and glycolysis, acting through the ERK1/2/NRF2/NFE2L2 axis (By similarity), May play a role in angiogenesis during fracture healing (By similarity), In this process, may regulate activation of the canonical NF-kappa-B signal in bone mesenchymal stem cells by enhancing the interaction between NEMO and 'Lys-63'-ubiquitinated RIPK1/RIP1, eventually leading to enhanced production of VEGFA and others angiogenic factors (PubMed:31502302), Essential for VEGF signaling through the activation of phospholipase C-gamma and ERK1/2, hence may control endothelial cell proliferation and angiogenesis (PubMed:19273721)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSLRSQSDLDDQHDYDSVASDEDTDQEPLRSTGATRSNRARSMDSSDLSDGAVTLQEYLELKKALATSEAKVQQLMKVNSSLSDELRRLQREIHKLQAENLQLRQPPGPVPTPPLPSERAEHTPMAPGGSTHRRDRQAFSMYEPGSALKPFGGPPGDELTTRLQPFHSTELEDDAIYSVHVPAGLYRIRKGVSASAVPFTPSSPLLSCSQEGSRHTSKLSRHGSGADSDYENTQSGDPLLGLEGKRFLELGKEEDFHPELESLDGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRSSLRLLNASAYRLQSECRKTVPPEPGAPVDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 761, "molWeight": 84341, "crc64": "702744942A796399", "md5": "E97F00FB13B88C42370996299D0ABBD6"}}
{"primaryAccession": "Q9Y2Y4", "text": "This is Zinc finger and BTB domain-containing protein 32 protein, from Human, contains 487 amino acids, has 3 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [373, 395], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [401, 423], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [428, 450], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9Y2Y4", "organism_name": "Human", "protein_name": "Zinc finger and BTB domain-containing protein 32", "length": 487, "firstPublicDate": "2007-01-23", "FUNCTION": "DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence, May function as a transcriptional transactivator and transcriptional repressor, Probably exerts its repressor effect by preventing GATA3 from binding to DNA, May play a role in regulating the differentiation and activation of helper T-cells (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 3}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSLPPIRLPSPYGSDRLVQLAARLRPALCDTLITVGSQEFPAHSLVLAGVSQQLGRRGQWALGEGISPSTFAQLLNFVYGESVELQPGELRPLQEAARALGVQSLEEACWRARGDRAKKPDPGLKKHQEEPEKPSRNPERELGDPGEKQKPEQVSRTGGREQEMLHKHSPPRGRPEMAGATQEAQQEQTRSKEKRLQAPVGQRGADGKHGVLTWLRENPGGSEESLRKLPGPLPPAGSLQTSVTPRPSWAEAPWLVGGQPALWSILLMPPRYGIPFYHSTPTTGAWQEVWREQRIPLSLNAPKGLWSQNQLASSSPTPGSLPQGPAQLSPGEMEESDQGHTGALATCAGHEDKAGCPPRPHPPPAPPARSRPYACSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCSLCGAGCPSLASMQAHMRGHSPSQLPPGWTIRSTFLYSSSRPSRPSTSPCCPSSSTT", "length": 487, "molWeight": 52963, "crc64": "B528F3C2AFFC4838", "md5": "F857850FD79E6E2EDE88FA62B6596777"}}
{"primaryAccession": "Q9Y2Z4", "text": "This is Tyrosine--tRNA ligase, mitochondrial protein, from Human, contains 477 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y2Z4", "organism_name": "Human", "protein_name": "Tyrosine--tRNA ligase, mitochondrial", "length": 477, "firstPublicDate": "2004-07-19", "FUNCTION": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the class-I aminoacyl-tRNA synthetase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAPILRSFSWGRWSGTLNLSVLLPLGLRKAHSGAQGLLAAQKARGLFKDFFPETGTKIELPELFDRGTASFPQTIYCGFDPTADSLHVGHLLALLGLFHLQRAGHNVIALVGGATARLGDPSGRTKEREALETERVRANARALRLGLEALAANHQQLFTDGRSWGSFTVLDNSAWYQKQHLVDFLAAVGGHFRMGTLLSRQSVQLRLKSPEGMSLAEFFYQVLQAYDFYYLFQRYGCRVQLGGSDQLGNIMSGYEFINKLTGEDVFGITVPLITSTTGAKLGKSAGNAVWLNRDKTSPFELYQFFVRQPDDSVERYLKLFTFLPLPEIDHIMQLHVKEPERRGPQKRLAAEVTKLVHGREGLDSAKRCTQALYHSSIDALEVMSDQELKELFKEAPFSEFFLDPGTSVLDTCRKANAIPDGPRGYRMITEGGVSINHQQVTNPESVLIVGQHILKNGLSLLKIGKRNFYIIKWLQL", "length": 477, "molWeight": 53199, "crc64": "C513B8FE1E7A09E4", "md5": "B16B2E18A0B40DB93FC8AE61656F3AFA"}}
{"primaryAccession": "Q9Y3P8", "text": "This is Signaling threshold-regulating transmembrane adapter 1 protein, from Human, contains 196 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y3P8", "organism_name": "Human", "protein_name": "Signaling threshold-regulating transmembrane adapter 1", "length": 196, "firstPublicDate": "2005-12-20", "FUNCTION": "Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells, Involved in positive selection of T-cells", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNQADPRLRAVCLWTLTSAAMSRGDNCTDLLALGIPSITQAWGLWVLLGAVTLLFLISLAAHLSQWTRGRSRSHPGQGRSGESVEEVPLYGNLHYLQTGRLSQDPEPDQQDPTLGGPARAAEEVMCYTSLQLRPPQGRIPGPGTPVKYSEVVLDSEPKSQASGPEPELYASVCAQTRRARASFPDQAYANSQPAAS", "length": 196, "molWeight": 21126, "crc64": "2A0C48C9466F7F07", "md5": "144AC2278CFB86288D5DAA12336528C2"}}
{"primaryAccession": "Q9Y4X5", "text": "This is E3 ubiquitin-protein ligase ARIH1 protein, from Human, contains 557 amino acids, has 1 RING-type Zinc finger, has 1 IBR-type Zinc finger, has 1 RING-type 2; atypical Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [186, 236], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [256, 317], "description": "IBR-type", "keyword_description": "Zinc finger", "textural_description": "IBR-type Zinc finger"}, {"location": [344, 375], "description": "RING-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "RING-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9Y4X5", "organism_name": "Human", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "length": 557, "firstPublicDate": "2001-09-26", "FUNCTION": "E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (PubMed:15236971, PubMed:21532592, PubMed:24076655, PubMed:27565346, PubMed:23707686), Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-RING ubiquitin ligase (CRL) complexes and initiating ubiquitination of CRL substrates: associates with CRL complexes and specifically mediates addition of the first ubiquitin on CRLs targets (PubMed:27565346), The initial ubiquitin is then elongated by CDC34/UBE2R1 and UBE2R2 (PubMed:27565346), E3 ubiquitin-protein ligase activity is activated upon binding to neddylated cullin-RING ubiquitin ligase complexes (PubMed:24076655, PubMed:27565346), Plays a role in protein translation in response to DNA damage by mediating ubiquitination of EIF4E2, the consequences of EIF4E2 ubiquitination are however unclear (PubMed:25624349), According to a report, EIF4E2 ubiquitination leads to promote EIF4E2 cap-binding and protein translation arrest (PubMed:25624349), According to another report EIF4E2 ubiquitination leads to its subsequent degradation (PubMed:14623119), Acts as the ligase involved in ISGylation of EIF4E2 (PubMed:17289916), In vitro, controls the degradation of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex member SUN2 and may therefore have a role in the formation and localization of the LINC complex, and as a consequence, nuclear subcellular localization and nuclear morphology (PubMed:29689197)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the RBR family, Ariadne subfamily", "domain_description": {"RING-type Zinc finger": 1, "IBR-type Zinc finger": 1, "RING-type 2; atypical Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDSDEGYNYEFDEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED", "length": 557, "molWeight": 64118, "crc64": "DFFF8965DAB41DC8", "md5": "8DA1CC7C785CA704FA2C99756EEEC9F3"}}
{"primaryAccession": "Q9Y5J1", "text": "This is U3 small nucleolar RNA-associated protein 18 homolog protein, from Human, contains 556 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y5J1", "organism_name": "Human", "protein_name": "U3 small nucleolar RNA-associated protein 18 homolog", "length": 556, "firstPublicDate": "2001-11-16", "FUNCTION": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit, During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome, Involved in nucleolar processing of pre-18S ribosomal RNA", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WD repeat UTP18 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPPERRRRMKLDRRTGAKPKRKPGMRPDWKAGAGPGGPPQKPAPSSQRKPPARPSAAAAAIAVAAAEEERRLRQRNRLRLEEDKPAVERCLEELVFGDVENDEDALLRRLRGPRVQEHEDSGDSEVENEAKGNFPPQKKPVWVDEEDEDEEMVDMMNNRFRKDMMKNASESKLSKDNLKKRLKEEFQHAMGGVPAWAETTKRKTSSDDESEEDEDDLLQRTGNFISTSTSLPRGILKMKNCQHANAERPTVARISSVQFHPGAQIVMVAGLDNAVSLFQVDGKTNPKIQSIYLERFPIFKACFSANGEEVLATSTHSKVLYVYDMLAGKLIPVHQVRGLKEKIVRSFEVSPDGSFLLINGIAGYLHLLAMKTKELIGSMKINGRVAASTFSSDSKKVYASSGDGEVYVWDVNSRKCLNRFVDEGSLYGLSIATSRNGQYVACGSNCGVVNIYNQDSCLQETNPKPIKAIMNLVTGVTSLTFNPTTEILAIASEKMKEAVRLVHLPSCTVFSNFPVIKNKNISHVHTMDFSPRSGYFALGNEKGKALMYRLHHYSDF", "length": 556, "molWeight": 62004, "crc64": "800139F974F4EDF6", "md5": "870F633FBD7E2AF043DBDD1E24528641"}}
{"primaryAccession": "Q9Y5J6", "text": "This is Mitochondrial import inner membrane translocase subunit Tim10 B protein, from Human, contains 103 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y5J6", "organism_name": "Human", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim10 B", "length": 103, "firstPublicDate": "2001-01-11", "FUNCTION": "Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane, The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force, In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the small Tim family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MERQQQQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVQLMPALVQRRIADYEAASAVPGVAAEQPGVSPSGS", "length": 103, "molWeight": 11586, "crc64": "B76CCC81668B1F31", "md5": "BAE24D20D58F3A39665009BB19D95EC3"}}
{"primaryAccession": "Q9Y5U4", "text": "This is Insulin-induced gene 2 protein protein, from Human, contains 225 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y5U4", "organism_name": "Human", "protein_name": "Insulin-induced gene 2 protein", "length": 225, "firstPublicDate": "2007-05-15", "FUNCTION": "Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR (PubMed:12242332, PubMed:16606821, PubMed:32322062), Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2 (PubMed:32322062), Binds oxysterol, including 22-hydroxycholesterol, 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol, regulating interaction with SCAP and retention of the SCAP-SREBP complex in the endoplasmic reticulum (PubMed:26160948, PubMed:17428920, PubMed:32322062), In presence of oxysterol, interacts with SCAP, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing SCAP from escorting SREBF1/SREBP1 and SREBF2/SREBP2 to the Golgi (PubMed:32322062), Sterol deprivation or phosphorylation by PCK1 reduce oxysterol-binding, disrupting the interaction between INSIG2 and SCAP, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBF1/SREBP1 and SREBF2/SREBP2 (PubMed:32322062), Also regulates cholesterol synthesis by regulating degradation of HMGCR: initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase RNF139 (PubMed:16606821, PubMed:22143767)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the INSIG family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAEGETESPGPKKCGPYISSVTSQSVNLMIRGVVLFFIGVFLALVLNLLQIQRNVTLFPPDVIASIFSSAWWVPPCCGTASAVIGLLYPCIDRHLGEPHKFKREWSSVMRCVAVFVGINHASAKVDFDNNIQLSLTLAALSIGLWWTFDRSRSGFGLGVGIAFLATVVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE", "length": 225, "molWeight": 24778, "crc64": "13E0392F1B30F08C", "md5": "A2DD3198E2506A04B4000C58B7DD8978"}}
{"primaryAccession": "Q9Y679", "text": "This is Lipid droplet-regulating VLDL assembly factor AUP1 protein, from Human, contains 410 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y679", "organism_name": "Human", "protein_name": "Lipid droplet-regulating VLDL assembly factor AUP1", "length": 410, "firstPublicDate": "2000-12-01", "FUNCTION": "(Microbial infection) Following Dengue virus infection, required for induction of lipophagy which facilitates production of virus progeny particles", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the AUP1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MELPSGPGPERLFDSHRLPGDCFLLLVLLLYAPVGFCLLVLRLFLGIHVFLVSCALPDSVLRRFVVRTMCAVLGLVARQEDSGLRDHSVRVLISNHVTPFDHNIVNLLTTCSTPLLNSPPSFVCWSRGFMEMNGRGELVESLKRFCASTRLPPTPLLLFPEEEATNGREGLLRFSSWPFSIQDVVQPLTLQVQRPLVSVTVSDASWVSELLWSLFVPFTVYQVRWLRPVHRQLGEANEEFALRVQQLVAKELGQTGTRLTPADKAEHMKRQRHPRLRPQSAQSSFPPSPGPSPDVQLATLAQRVKEVLPHVPLGVIQRDLAKTGCVDLTITNLLEGAVAFMPEDITKGTQSLPTASASKFPSSGPVTPQPTALTFAKSSWARQESLQERKQALYEYARRRFTERRAQEAD", "length": 410, "molWeight": 45787, "crc64": "1A06476225C5DFDC", "md5": "7FB98F50D85035FA40E2B83A630F6BE6"}}
{"primaryAccession": "Q9Y694", "text": "This is Solute carrier family 22 member 7 protein, from Human, contains 548 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y694", "organism_name": "Human", "protein_name": "Solute carrier family 22 member 7", "length": 548, "firstPublicDate": "2008-02-05", "FUNCTION": "Mediates sodium-independent multispecific organic anion transport, Transport of prostaglandin E2, prostaglandin F2-alpha, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYDHSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEEMPMKQVQN", "length": 548, "molWeight": 60026, "crc64": "5BA4C3FCC3C57533", "md5": "6B0489D8B772980C2863DE53CB508527"}}
{"primaryAccession": "Q9Y6H1", "text": "This is Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 protein, from Human, contains 151 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y6H1", "organism_name": "Human", "protein_name": "Coiled-coil-helix-coiled-coil-helix domain-containing protein 2", "length": 151, "firstPublicDate": "2005-04-12", "FUNCTION": "Transcription factor, Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) (PubMed:23303788)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMATTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQEPQGTQPAQQQQPCLYEIKQFLECAQNQGDIKLCEGFNEVLKQCRLANGLA", "length": 151, "molWeight": 15513, "crc64": "5403662D8DB4FB86", "md5": "BA258C36414B74C6E9C10B8B8098D14D"}}
{"primaryAccession": "Q9Y6J9", "text": "This is TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L protein, from Human, contains 622 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y6J9", "organism_name": "Human", "protein_name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "length": 622, "firstPublicDate": "2004-04-26", "FUNCTION": "Functions as a component of the PCAF complex, The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context, The PCAF complex could be considered as the human version of the yeast SAGA complex (Probable), With TAF5L, acts as an epigenetic regulator essential for somatic reprogramming, Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state, Functions with MYC to activate target gene expression through RNA polymerase II pause release (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TAF6 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEALPMRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYHQVTRAVLGDDPQLMKVALQDLQTNSKIGALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLFRNPHLCLGPYVRCLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQHILLSLQKILADPVRPLCCHYGAVVGLHALGWKAVERVLYPHLSTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGPGGRGCRRLDDLPWDSLLFQESSSGGGAEPSFGSGLPLPPGGAGPEDPSLSVTLADIYRELYAFFGDSLATRFGTGQPAPTAPRPPGDKKEPAAAPDSVRKMPQLTASAIVSPHGDESPRGSGGGGPASASGPAASESRPLPRVHRARGAPRQQGPGTGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTSRPARRWALSDYSLYLPL", "length": 622, "molWeight": 67814, "crc64": "F294E71AF7D4C8C3", "md5": "55FB9317562E55C1EC2C822DDDC19E5D"}}
{"primaryAccession": "Q9Y7L8", "text": "This is Small ribosomal subunit protein uS2A protein, from Fission yeast, contains 292 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y7L8", "organism_name": "Fission yeast", "protein_name": "Small ribosomal subunit protein uS2A", "length": 292, "firstPublicDate": "2001-08-14", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (By similarity), uS2 is required for the assembly and/or stability of the 40S ribosomal subunit, Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (PubMed:14623272)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the universal ribosomal protein uS2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAQVGRPNILNATDEDIKQLLAANCHIGSKNLEVRMDNYVWKRRSDGVHILNLGKTWEKLVLAARVIATIENPADVCVVSTRTYGHRAVLKFAAHTGATAIAGRFTPGNFTNYITRTYREPRLIVVTDPRADAQAIKEASFVNIPVIALCDTDSILNHVDIAIPTNNKGRKSIGLIWYLLAREVLRVRGTLSRSAPWDVMPDLYFYRDPEEVEREEEAKKAAAAAAEEAQVEEAVAAAEFEITDSAAGSVDPNVLAAATAGQVGENTWEGAGDWNTTGAAQTSDWTAAAEAQ", "length": 292, "molWeight": 31760, "crc64": "CE0DB640C7D20FEF", "md5": "3B15BD2FEE7872B78C7CE08779E34204"}}
{"primaryAccession": "Q9Y7Q6", "text": "This is Histone-lysine N-methyltransferase, H3 lysine-37 specific protein, from Fission yeast, contains 147 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y7Q6", "organism_name": "Fission yeast", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-37 specific", "length": 147, "firstPublicDate": "2008-02-05", "FUNCTION": "Histone lysine methyltransferase that specifically mono-, di-, and trimethylates 'Lys-37' of histone H3 to regulate sporulation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the class V-like SAM-binding methyltransferase superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRIPVIRSPLEIRDTERKGRGVFALEPIPAQTCIEISPVLMFSKEEYEQHGQYTVLNEYTYVWSEGKQGLALGLGSMFNHDRHPNVYWKKDNRNNYISYYTLREIKTNEELCISYGDHLWFEDEASSASRISPNEENEDFPLQNISL", "length": 147, "molWeight": 17209, "crc64": "44FBC2EBC2ED3E3D", "md5": "460D4C1073C553F7A45DC9EDC05887CC"}}
{"primaryAccession": "Q9Y7Y7", "text": "This is 1,3-beta-glucanosyltransferase gas4 protein, from Fission yeast, contains 456 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y7Y7", "organism_name": "Fission yeast", "protein_name": "1,3-beta-glucanosyltransferase gas4", "length": 456, "firstPublicDate": "2008-01-15", "FUNCTION": "Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall, Involved in spore wall assembly", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glycosyl hydrolase 72 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGVANIIYALFLLGPSIFLKATAQTHPIVIKGNAFFDSKTNERFYIRGVDYQPGGSSSLVDPLASRSCKKDVEIFKKLGINTVRVYQVDNSADHDKCMNALSEAGIYVILDLNTYRHSISRAHPALSYNKVYLQHLFATIDAFKGYDNVLGFFSGNEVVNDEDTTAITWVKAVTRDVKAYIKKHSDRHIPVGYSAADVAENRLQLAHYFNCGDESERADFYAFNMYEWCGYSSMTVSGYYDRIKEFSNYSIPLFLSEFGCNTVEINDDTTPNRPFTEIEAIYSHDMTPVFSGGLVYEYSAEPNHYGLVVIDKDDERRVSRNFITLMKQYAKTPNPKGDGGYKKAGSPSKCPANSTQFNAWEKLPEMPEGAKIYMEKGAGEPLGIEGPTNMWSPFHDGDDDESTSRRPKPKNKPSNVTSTTSYTSGMTSSSESGSSKIGVAFCQALFITVLIATLSF", "length": 456, "molWeight": 50763, "crc64": "F1B4FBFE5D1A7F8B", "md5": "C178885A575A00D83C686903AA6703BA"}}
{"primaryAccession": "Q9YGW7", "text": "This is Deleted in azoospermia-like protein, from Zebrafish, contains 229 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9YGW7", "organism_name": "Zebrafish", "protein_name": "Deleted in azoospermia-like", "length": 229, "firstPublicDate": "2004-03-01", "FUNCTION": "RNA-binding protein involved in gametogenesis in both males and females (PubMed:12296827), Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and promoting the translation of key transcripts (PubMed:12296827), Establishes oocyte polarity through interaction with Bucky ball (BUC) (Probable), Interacts with Bucky ball (BUC) mRNA to mediate Balbiani body formation and oocyte polarity during early oogenesis (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the RRM DAZ family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVQGVQLPVCLICGLYSQDIQKHRQGFPSSLKLSNGYILPEGKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKGYGFVYFSEDVDIQTIVDQPISFKGKKLKLGPAIMKERSSRSVSSPMIGPSQWVNPTPYMYCSCCPPGLAPPSPVFSGGNQYMQPYSYSSPPGIMVPQVPMNYAQTTYAYQYPLPQWCGEQRTRLVNQNFVDCGVQTLLTLM", "length": 229, "molWeight": 25548, "crc64": "B38C72218F009654", "md5": "1D47527E2CE14C276CFE0298E62DB2ED"}}
{"primaryAccession": "Q9Z0E8", "text": "This is Organic cation/carnitine transporter 2 protein, from Mouse, contains 557 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Z0E8", "organism_name": "Mouse", "protein_name": "Organic cation/carnitine transporter 2", "length": 557, "firstPublicDate": "2000-12-01", "FUNCTION": "Sodium-ion dependent, high affinity carnitine transporter, Involved in the active cellular uptake of carnitine, Transports one sodium ion with one molecule of carnitine (PubMed:10454528, PubMed:20722056), Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium, Also relative uptake activity ratio of carnitine to TEA is 11,3 (PubMed:10454528), May also contribute to regulate the transport of organic compounds in testis across the blood-testis-barrier (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLSSAWRNHSIPLETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQESCLDGWEYDKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSELQDLNSTKPQLHHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFFPESFGVPLPDTIDQMLRVKGIKQWQIQSQTRMQKDGEESPTVLKSTAF", "length": 557, "molWeight": 62780, "crc64": "6093F0EE9612B204", "md5": "CFC669E20B95000F8848A83A4641C112"}}
{"primaryAccession": "Q9Z0G8", "text": "This is WAS/WASL-interacting protein family member 3 protein, from Rat, contains 485 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Z0G8", "organism_name": "Rat", "protein_name": "WAS/WASL-interacting protein family member 3", "length": 485, "firstPublicDate": "2008-06-10", "FUNCTION": "May have a role in spermatogenesis (By similarity), May be a regulator of cytoskeletal organization", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the verprolin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPVPPPPPPPLPPPPPPLGAPPPPPPPGPPISTDAPSLRKSDLKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTSKEGGAAGSNARGGSTPPALGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPTKAISGPLPAPASPRLGNASDTHSSARPVPPRPSVPAPPPPTTPPPPPPPPPPPPPPPLPPASPIKAPSVSPPVPPTKGNPSAVPAPIPCVPPLPPPPPTPPPLPPASALSEKAVRPQLAPLHLPPIPPPLPLLPPYGYPALHSEPSSPAQDVREPPAPPPPPPPPPPPPPPPLPTYASCSPRAAVAPPPPPLPGSSNSGSETPPPLPPKSPSFQTQKALPTPPGAPGPQIILQKKRRGPGAGGGKLNPPPAPPARSPTTELSSKTQQPGGQLRNGGQHVIDDFESKFTFHSMEDFPPPDEYKPGQKIYPSKVPRSRTPGSWLQAEAAGQSSDDIKTRNSQLSLKALR", "length": 485, "molWeight": 49381, "crc64": "195673E854CB37D9", "md5": "F852F709292EB3DB9ABCC38BAD25199B"}}
{"primaryAccession": "Q9Z2E9", "text": "This is Seipin protein, from Mouse, contains 383 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Z2E9", "organism_name": "Mouse", "protein_name": "Seipin", "length": 383, "firstPublicDate": "2005-04-26", "FUNCTION": "Plays a crucial role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (By similarity),In association with LDAF1, defines the sites of LD formation in the ER (By similarity), Also required for growth and maturation of small nascent LDs into larger mature LDs (By similarity), Mediates the formation and/or stabilization of endoplasmic reticulum-lipid droplets (ER-LD) contacts, facilitating protein and lipid delivery from the ER into growing LDs (By similarity), Regulates the maturation of ZFYVE1-positive nascent LDs and the function of the RAB18-ZFYVE1 complex in mediating the formation of ER-LD contacts (By similarity), Binds anionic phospholipids including phosphatidic acid (By similarity), Plays an important role in the differentiation and development of adipocytes (PubMed:18458148, PubMed:19574402, PubMed:21551454, PubMed:22269949)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the seipin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVNDPPVPALLWAQEVGHVLAGRARRLMLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFHYRTDCDSSTASLCSFPVANVSLAKSGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHYRSQLLQVLDTLLFSSLLLFGFAEQKQLLEVELYSDYRENSYVPTTGAIIEIHSKRIQMYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIVLFSYMQWVWGAVWPRHRFSLQVNIRQRDNSHHGAPRRISRHQPGQESTQQSDVTEDGESPEDPSGTEGQLSEEEKPEKRPLNGEEEQEPEASDGSWEDAALLTEANPPTSASASALAPETLGSLRQRPTCSSS", "length": 383, "molWeight": 43105, "crc64": "AB185C29BC67634E", "md5": "D1C8EB11207B6A2B6049A124B5735590"}}
{"primaryAccession": "Q9Z325", "text": "This is Dolichol phosphate-mannose biosynthesis regulatory protein protein, from Rat, contains 84 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Z325", "organism_name": "Rat", "protein_name": "Dolichol phosphate-mannose biosynthesis regulatory protein", "length": 84, "firstPublicDate": "2000-05-30", "FUNCTION": "Regulates the biosynthesis of dolichol phosphate-mannose (PubMed:9724629), Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1 (PubMed:9724629), Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis, May act by regulating the GPI-GNT complex (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DPM2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATGTDQAVGFGLVAVSLIIFTYYTTWVILLPFIDSQHVIHKYFLPRAYAVLLPLAAGLLLLLFVGLFITYVLLKSQKVTKKAQ", "length": 84, "molWeight": 9344, "crc64": "345C9AC265573300", "md5": "AC329146231866BF7D5DDB5F27FA7EFE"}}
{"primaryAccession": "Q9ZSK3", "text": "This is Actin-depolymerizing factor 4 protein, from Mouse-ear cress, contains 139 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ZSK3", "organism_name": "Mouse-ear cress", "protein_name": "Actin-depolymerizing factor 4", "length": 139, "firstPublicDate": "2001-11-02", "FUNCTION": "Actin-depolymerizing protein, Severs actin filaments (F-actin) and binds to actin monomers (PubMed:19346440, PubMed:22010035), Contributes to the stochastic dynamic turnover of actin filaments (PubMed:22010035), Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin, Involved in resistance triggered by the effector AvrPphB of Pseudomonas syringae pv tomato (Pst), May modulate the AvrPphB-RPS5-mediated defense signal transduction pathway (PubMed:19346440), During AvrPphB-triggered resistance signaling pathway, involved in the control of MPK3 and MPK6 activation, via the coordinated regulation of actin cytoskeletal dynamics and RPS5 resistance gene transcription (PubMed:23144618), During innate immune response triggered by the bacterial elf26 peptide, the inhibition of ADF4 regulates actin dynamics in order to execute key events associated with pattern-triggered immunity (PTI), such as cell wall fortification and transcriptional activation of defense gene markers (PubMed:24464292)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the actin-binding proteins ADF family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MANAASGMAVHDDCKLRFLELKAKRTHRFIVYKIEEKQKQVIVEKVGEPILTYEDFAASLPADECRYAIYDFDFVTAENCQKSKIFFIAWCPDVAKVRSKMIYASSKDRFKRELDGIQVELQATDPTEMDLDVLKSRVN", "length": 139, "molWeight": 16034, "crc64": "57F95F557F42F863", "md5": "D431F8E4996DADDF269459725F5E697C"}}
{"primaryAccession": "Q9ZUX7", "text": "This is tRNA dimethylallyltransferase 2 protein, from Mouse-ear cress, contains 466 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ZUX7", "organism_name": "Mouse-ear cress", "protein_name": "tRNA dimethylallyltransferase 2", "length": 466, "firstPublicDate": "2010-02-09", "FUNCTION": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A), Involved in the cis-type cytokinin biosynthesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the IPP transferase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMMLNPSNGGIEGEKMKKKAKVVVIMGPTGSGKSKLAVDLASHFPVEIINADAMQIYSGLDVLTNKVTVDEQKGVPHHLLGTVSSDMEFTARDFRDFTVPLIEEIVSRNHIPVLVGGTHYYIQAVVSKFLLDDAAEDTEECCADVASVVDQDMVVESVFGRDDLSHGYELLKELDPVAANRIHPNNHRKINQYLSLHASRGVLPSKLYQGKTAENWGCINASRFDYCLICMDAETAVLDRYVEQRVDAMVDAGLLDEVYDIYKPGADYTRGLRQSIGVREFEDFLKIHLSETCAGHLTSLSNDDKVMKENLRKILNFPKDDKLRIMLEEAIDRVKLNTRRLLRRQKRRVSRLETVFGWNIHYIDATEYILSKSEESWNAQVVKPASEIIRCFLETETESGRDPTSGKSIERDLWTQYVCEACGNKILRGRHEWEHHKQGRTHRKRTTRHKNSQTYKNREVQEAEVN", "length": 466, "molWeight": 53098, "crc64": "FA95EADE815FBADA", "md5": "DEF1C0B15DC479A59E8F829E8DD0CC60"}}
{"primaryAccession": "Q9ZUY3", "text": "This is Arogenate dehydratase 3, chloroplastic protein, from Mouse-ear cress, contains 424 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ZUY3", "organism_name": "Mouse-ear cress", "protein_name": "Arogenate dehydratase 3, chloroplastic", "length": 424, "firstPublicDate": "2009-05-05", "FUNCTION": "Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine (PubMed:17726025), Together with GCR1 and GPA1, required for blue light-mediated synthesis of phenylpyruvate and subsequently of phenylalanine (Phe), in etiolated seedlings (PubMed:16415218)", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRTLLPSHTPATVTTAARRRHVIHCAGKRSDSFSINSSSSDWQSSCAILSSKVNSQEQSESLSSNSNGSSSYHVSAVNGHNNGAGVSDLNLVPFNNNQSIQSKKPLSISDLSPAPMHGSNLRVAYQGVPGAYSEAAAGKAYPNCQAIPCDQFEVAFQAVELWIADRAVLPVENSLGGSIHRNYDLLLRHRLHIVGEVQLPVHHCLIALPGVRKEFLTRVISHPQGLAQCEHTLTKLGLNVAREAVDDTAGAAEFIAANNIRDTAAIASARAAEIYGLEILEDGIQDDASNVTRFVMLAREPIIPRTDRPFKTSIVFAHEKGTCVLFKVLSAFAFRNISLTKIESRPNHNVPIRLVDEANVGTAKHFEYMFYIDFEASMAESRAQNALSEVQEFTSFLRVLGSYPMDMTSWSPSSSSSSSSTFSL", "length": 424, "molWeight": 46102, "crc64": "52471CE9914FDA89", "md5": "E3F0CF524E83EC7BA46F6363D0E7293D"}}
{"primaryAccession": "Q9ZV65", "text": "This is Homeobox-leucine zipper protein HDG3 protein, from Mouse-ear cress, contains 725 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ZV65", "organism_name": "Mouse-ear cress", "protein_name": "Homeobox-leucine zipper protein HDG3", "length": 725, "firstPublicDate": "2008-04-29", "FUNCTION": "Probable transcription factor (By similarity), Seems to promote cell differentiation (PubMed:25564655)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the HD-ZIP homeobox family, Class IV subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSQSNMVPVANNGDNNNDNENNNNNNNNGGTDNTNAGNDSGDQDFDSGNTSSGNHGEGLGNNQAPRHKKKKYNRHTQLQISEMEAFFRECPHPDDKQRYDLSAQLGLDPVQIKFWFQNKRTQNKNQQERFENSELRNLNNHLRSENQRLREAIHQALCPKCGGQTAIGEMTFEEHHLRILNARLTEEIKQLSVTAEKISRLTGIPVRSHPRVSPPNPPPNFEFGMGSKGNVGNHSRETTGPADANTKPIIMELAFGAMEELLVMAQVAEPLWMGGFNGTSLALNLDEYEKTFRTGLGPRLGGFRTEASRETALVAMCPTGIVEMLMQENLWSTMFAGIVGRARTHEQIMADAAGNFNGNLQIMSAEYQVLSPLVTTRESYFVRYCKQQGEGLWAVVDISIDHLLPNINLKCRRRPSGCLIQEMHSGYSKVTWVEHVEVDDAGSYSIFEKLICTGQAFAANRWVGTLVRQCERISSILSTDFQSVDSGDHITLTNHGKMSMLKIAERIARTFFAGMTNATGSTIFSGVEGEDIRVMTMKSVNDPGKPPGVIICAATSFWLPAPPNTVFDFLREATHRHNWDVLCNGEMMHKIAEITNGIDKRNCASLLRHGHTSKSKMMIVQETSTDPTASFVLYAPVDMTSMDITLHGGGDPDFVVILPSGFAIFPDGTGKPGGKEGGSLLTISFQMLVESGPEARLSVSSVATTENLIRTTVRRIKDLFPCQTA", "length": 725, "molWeight": 80070, "crc64": "F3F524152017C2F7", "md5": "339DD380B350C2C1CF1B30CA5F5DDE3A"}}
{"primaryAccession": "Q9ZVH8", "text": "This is Transcription elongation factor TFIIS protein, from Mouse-ear cress, contains 378 amino acids, has 1 TFIIS-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [336, 376], "description": "TFIIS-type", "keyword_description": "Zinc finger", "textural_description": "TFIIS-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9ZVH8", "organism_name": "Mouse-ear cress", "protein_name": "Transcription elongation factor TFIIS", "length": 378, "firstPublicDate": "2015-04-29", "FUNCTION": "Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites (Probable), Involved in the control of seed dormancy and germination (PubMed:19150360, PubMed:21799800)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"TFIIS-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MESDLIDLFEGAKKAADAAALDGVTSSGPEVSQCIDALKQLKKFPVTYDTLVATQVGKKLRSLAKHPVEDIKSVATDLLEIWKKVVIEETAKAKKTEGTNGCKEAKVNKMDVEKPSNPAPVKVQKLQRGDSAKSIKVERKEPDNKVVTGVKIERKVPDIKVTNGTKIDYRGQAVKDEKVSKDNQSSMKAPAKAANAPPKLTAMLKCNDPVRDKIRELLVEALCRVAGEADDYERESVNASDPLRVAVSVESLMFEKLGRSTGAQKLKYRSIMFNLRDSNNPDLRRRVLTGEISPEKLITLSAEDMASDKRKQENNQIKEKALFDCERGLAAKASTDQFKCGRCGQRKCTYYQMQTRSADEPMTTYVTCVNCDNHWKFC", "length": 378, "molWeight": 41979, "crc64": "9A176DC31FA8E885", "md5": "4A0ACA04345E39B60FBB39F5FB323E81"}}
{"primaryAccession": "Q9ZWA6", "text": "This is Zinc finger protein MAGPIE protein, from Mouse-ear cress, contains 506 amino acids, has 2 C2H2-type Zinc finger, has 1 C2H2-type 2; degenerate Zinc finger, has 1 CCHC-type 2; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [70, 92], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [111, 141], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [146, 169], "description": "C2H2-type 2; degenerate", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 2; degenerate Zinc finger"}, {"location": [173, 196], "description": "CCHC-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "CCHC-type 2; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9ZWA6", "organism_name": "Mouse-ear cress", "protein_name": "Zinc finger protein MAGPIE", "length": 506, "firstPublicDate": "2008-06-10", "FUNCTION": "Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440), Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440), Interacts with the SCR and MGP promoters (PubMed:21935722), Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722), Binds DNA via its zinc fingers (PubMed:24821766), Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766), Positively involved in gibberellic acid (GA) signaling (PubMed:24821766)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 2, "C2H2-type 2; degenerate Zinc finger": 1, "CCHC-type 2; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTTEDQTISSSGGYVQSSSTTDHVDHHHHDQHESLNPPLVKKKRNLPGNPDPEAEVIALSPKTLMATNRFLCEICGKGFQRDQNLQLHRRGHNLPWKLKQRTSKEVRKRVYVCPEKSCVHHHPTRALGDLTGIKKHFCRKHGEKKWKCEKCAKRYAVQSDWKAHSKTCGTREYRCDCGTIFSRRDSFITHRAFCDALAEETARLNAASHLKSFAATAGSNLNYHYLMGTLIPSPSLPQPPSFPFGPPQPQHHHHHQFPITTNNFDHQDVMKPASTLSLWSGGNINHHQQVTIEDRMAPQPHSPQEDYNWVFGNANNHGELITTSDSLITHDNNINIVQSKENANGATSLSVPSLFSSVDQITQDANAASVAVANMSATALLQKAAQMGATSSTSPTTTITTDQSAYLQSFASKSNQIVEDGGSDRFFASFGSNSVELMSNNNNGLHEIGNPRNGVTVVSGMGELQNYPWKRRRVDIGNAGGGGQTRDFLGVGVQTICHSSSINGWI", "length": 506, "molWeight": 55826, "crc64": "C27006B44C77D1C7", "md5": "74BBAEBD6866AB44F477DAB93BC37907"}}
{"primaryAccession": "W3VKA4", "text": "This is Lipase A protein, from Pseudozyma aphidis, contains 462 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "W3VKA4", "organism_name": "Pseudozyma aphidis", "protein_name": "Lipase A", "length": 462, "firstPublicDate": "2015-05-27", "FUNCTION": "Hydrolyzes triglycerides, with a preference for substrates with short-chain lengths (C4 to C8), Has the highest activity with tributyrin (C4), followed by tricaproin (C6) and tricaprylin (C8), Can also hydrolyze vinylacetate (C2) and triolein (C18), but with lower efficiency, Has no activity with tripalmitin (C16)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRVSLRSITSLLAAATAAVLAAPATETLDRRAALPNPYDDPFYTTPSNIGTFAKGQVIQSRKVPTDIGNANNAASFQLQYRTTNTQNEAVADVATVWIPAKPASPPKIFSYQVYEDATALDCAPSYSYLTGLDQPNKVTAVLDTPIIIGWALQQGYYVVSSDHEGFKAAFIAGYEEGMAILDGIRALKNYQNLPSDSKVALEGYSGGAHATVWATSLADSYAPELNIVGASHGGTPVSAKDTFTFLNGGPFAGFALAGVSGLSLAHPDMESFIEARLNAKGQQTLKQIRGRGFCLPQVVLTYPFLNVFSLVNDTNLLNEAPIAGILKQETVVQAEASYTVSVPKFPRFIWHAIPDEIVPYQPAATYVKEQCAKGANINFSPYPIAEHLTAEIFGLVPSLWFIKQAFDGTTPKVICGTPIPAIAGITTPSADQVLGSDLANQLRSLNGKQSAFGKPFGPITPP", "length": 462, "molWeight": 49265, "crc64": "700908D4C645981B", "md5": "89753A8A9273372D23CAD71E52F6BD44"}}
{"primaryAccession": "A0AQW4", "text": "This is Transcription factor TCP12 protein, from Mouse-ear cress, contains 356 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A0AQW4", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor TCP12", "length": 356, "firstPublicDate": "2008-04-29", "FUNCTION": "Transcription factor that prevents axillary bud outgrowth, May also delay early axillary bud development, Probably involved in the auxin-induced control of apical dominance", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFPSLDTNGYDLFDPFIPHQTTMFPSFITHIQSPNSHHHYSSPSFPFSSDFLESFDESFLINQFLLQQQDVAANVVESPWKFCKKLELKKKNEKCVDGSTSQEVQWRRTVKKRDRHSKICTAQGPRDRRMRLSLQIARKFFDLQDMLGFDKASKTIEWLFSKSKTSIKQLKERVAASEGGGKDEHLQVDEKEKDETLKLRVSKRRTKTMESSFKTKESRERARKRARERTMAKMKMRLFETSETISDPHQETREIKITNGVQLLEKENKEQEWSNTNDVHMVEYQMDSVSIIEKFLGLTSDSSSSSIFGDSEECYTSLSSVRGMSTPREHNTTSIATVDEEKSPISSFSLYDYLCY", "length": 356, "molWeight": 41366, "crc64": "DD3AABE85C6D2C71", "md5": "4046500806311C6F4C1AF593FAD3596F"}}
{"primaryAccession": "A5D6W6", "text": "This is Fat storage-inducing transmembrane protein 1 protein, from Human, contains 292 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A5D6W6", "organism_name": "Human", "protein_name": "Fat storage-inducing transmembrane protein 1", "length": 292, "firstPublicDate": "2008-02-26", "FUNCTION": "Plays an important role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (PubMed:18160536) (By similarity), Directly binds to diacylglycerol (DAGs) and triacylglycerol (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the FIT family, FIT1 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MERGPVVGAGLGAGARIQALLGCLLKVLLWVASALLYFGSEQAARLLGSPCLRRLYHAWLAAVVIFGPLLQFHVNPRTIFASHGNFFNIKFVNSAWGWTCTFLGGFVLLVVFLATRRVAVTARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLPQGLLLHELPDRRSCLAAGHQWRGYTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAPLRLVFLLNVLLLGLWNFLLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQPWSPGSPGHGLFPRPHSSRKHN", "length": 292, "molWeight": 32207, "crc64": "5722083EB85EEDC8", "md5": "C25758A5FD85E146FC5F304B03989AC2"}}
{"primaryAccession": "A8IVX2", "text": "This is Dynein regulatory complex subunit 3 protein, from Chlamydomonas smithii, contains 524 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A8IVX2", "organism_name": "Chlamydomonas smithii", "protein_name": "Dynein regulatory complex subunit 3", "length": 524, "firstPublicDate": "2016-01-20", "FUNCTION": "Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (PubMed:23427265, PubMed:25411337), Required for normal flagellar waveform (PubMed:26063732)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the DRC3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPSLERLIAEVEPNVITESLTRECIQIQGGEPDTAANKKRTMPFRDVECLAFSFKNLACVDNLRGLDTLTKLQLDNNQITKIENLAHLTNLTWLDLSFNKITAISGLETLTKLVDLSLFNNQIAKIENLDTLVNLNVLSLGNNQLSQLDNVMYLRQFKQLRLVNLAGNPICKSHDYRSYVLSHIKDLIYLDYRRVNPADVQAAREQHQDEMIELQEREEQQSQEEKLNAERESHEKLMKQANLEGVETLIDDMVKEDLEWPRLSQVPSLLDPWNEIRDKFNTYTDEFKVAILEQHNKKKAEYEEWLGVVRSYLDEKDAEARKLIVEYEKAKKRTARVVVDQPLMAESQIDNLKVKLMALKDQLMAIEMEAVEVLDGLVQEFDRAYSELAEINKGQYNGYFTQVRDLQNSFFNQLTSVAMTVFEKYNQENSDIESLPEEARTLLQDKDSLMNALQASHDAHMGKIDSLEDRLVSNELRSANDLTSSNATWATKRNRDRISEIINYLERNVLELEELAGEEEGGEM", "length": 524, "molWeight": 60409, "crc64": "370669A342D6D463", "md5": "D0A37F734F522E74FD6690A09645ED77"}}
{"primaryAccession": "B0FHH8", "text": "This is MD-2-related lipid-recognition protein protein, from Tobacco hawkmoth, contains 151 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B0FHH8", "organism_name": "Tobacco hawkmoth", "protein_name": "MD-2-related lipid-recognition protein", "length": 151, "firstPublicDate": "2011-04-05", "FUNCTION": "Binds to lipopolysaccharide from a variety of Gram-negative bacteria and to lipid A", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the NPC2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAALHWLLLAALLGCTLAEEQAIFYNCEEASEAVCSVKEVRINPCNPNKKCIFKKGVNASISFDFEPNFASSKLVTTLYGPFDVEFDEMTNVDACQYTKCPTEPGKSQVLDYTLYIGKKLPQGTYTFKWKLWNPEETSQLCCFKTTIKIRK", "length": 151, "molWeight": 17102, "crc64": "25E56BE43F6E7242", "md5": "BE83B05FE7DAE54823AE729F38F79490"}}
{"primaryAccession": "B2RNN3", "text": "This is Complement C1q and tumor necrosis factor-related protein 9B protein, from Human, contains 333 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B2RNN3", "organism_name": "Human", "protein_name": "Complement C1q and tumor necrosis factor-related protein 9B", "length": 333, "firstPublicDate": "2008-09-02", "FUNCTION": "Probable adipokine, Activates AMPK, AKT, and p44/42 MAPK signaling pathways", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRIWWLLLAIEICTGNINSQDTCRQGHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGCPGSPGKDGTSGEKGERGADGKVEAKGIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGETGPQGQKGNKGDVGPTGPEGPRGNIGPLGPTGLPGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEKGKIGETLVLPKSAFTVGLTVLSKFPSSDVPIKFDKILYNEFNHYDTAVGKFTCHIAGVYYFTYHITVFSRNVQVSLVKNGVKILHTRDAYVSSEDQASGSIVLQLKLGDEMWLQVTGGERFNGLFADEDDDTTFTGFLLFSSQ", "length": 333, "molWeight": 34713, "crc64": "A15F3F7546938A70", "md5": "5F80605ED8035096C6298025C6944EB1"}}
{"primaryAccession": "B3FIV1", "text": "This is Omega-theraphotoxin-Bs2a protein, from Mexican red knee tarantula, contains 99 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3FIV1", "organism_name": "Mexican red knee tarantula", "protein_name": "Omega-theraphotoxin-Bs2a", "length": 99, "firstPublicDate": "2009-01-20", "FUNCTION": "Has minor, but significant effects on the Para/tipE insect sodium channel", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 14 (magi-1) family, 08 (Ltx-4) subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNTIQVIIFAVVLVLTVTVGQADEDSAETSLLRKLEEAEAAMFGQYLEESKNSREKRCIGESVPCDKDDPRCCREYECLKPTGYGWWYASYYCYRKKSG", "length": 99, "molWeight": 11336, "crc64": "D4323457785DAD08", "md5": "8643505FE7BB05B0F3028385C8BC5212"}}
{"primaryAccession": "B3VZU0", "text": "This is Brevinin-1CDYa protein, from Dybovsky's frog, contains 67 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3VZU0", "organism_name": "Dybovsky's frog", "protein_name": "Brevinin-1CDYa", "length": 67, "firstPublicDate": "2010-02-09", "FUNCTION": "Antimicrobial peptide, Has low activity against the Gram-positive bacterium S,aureus (MIC=12,5 uM) and the Gram-negative bacterium E,coli (MIC=25 uM), Has weak hemolytic activity against human erythrocytes", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTLKKSLLLIFFLGTINLSLCEEERNADEEERRDDLEERDVEVEKRLLSLALAALPKLFCLIFKKC", "length": 67, "molWeight": 7861, "crc64": "F288DCE240CFF2E2", "md5": "ACBFE716D48EE0D048EF0E166395F5A8"}}
{"primaryAccession": "B6RGY0", "text": "This is Peptide deformylase 1A, chloroplastic protein, from Rice, contains 260 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B6RGY0", "organism_name": "Rice", "protein_name": "Peptide deformylase 1A, chloroplastic", "length": 260, "firstPublicDate": "2009-04-14", "FUNCTION": "Removes the formyl group from the N-terminal Met of newly synthesized proteins", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the polypeptide deformylase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEAHLRPLSAAALLLSPAAPLPTAVAASARRASPGGRRWSSVRASAGGGGWLSGLLGGKGGGGAPTAMTVTPGTVKAGDPVLHEPAQDVAPGDIPSEKVQGVIDRMVAVMRKAPGVGLAAPQIGVPLKIIVLEDTQEYISYAPKKDIEAQDRRPFDLLVIINPKLKTTSKRTALFFEGCLSVDGYRALVERHLDVEVSGLDRNGRPIKVEASGWQARILQHECDHLEGTLYVDTMVPRTFRIVDNLDLPLPVGCPPIGAR", "length": 260, "molWeight": 27493, "crc64": "A0CEB3C83E884CCE", "md5": "C3F043FD8EE8FE1EA9FDDBE9CE8BDE4F"}}
{"primaryAccession": "B9V5F5", "text": "This is Centrosomal protein of 63 kDa-A protein, from African clawed frog, contains 649 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B9V5F5", "organism_name": "African clawed frog", "protein_name": "Centrosomal protein of 63 kDa-A", "length": 649, "firstPublicDate": "2009-09-01", "FUNCTION": "Required for normal spindle assembly (PubMed:19182792), Plays a key role in mother-centriole-dependent centriole duplication (PubMed:19182792), Plays a role in DNA damage response (PubMed:19182792), Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (PubMed:19182792)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CEP63 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEALLQGLQRQDRMGALQDSCEAELQELMKQIDIMLDHKRSQWEAETETMKTRLELKEQELNCALDREERLNQEVRRLRQQLIQQEEETQNKTTQYEAQLSGFKEELNRLKKSYEKVQKKHLRSEMKAKAEEERSEVSRLTRRLEEFRQRSLDWEKQRLLYQQQLAGLEAQRKTLIEQTEMYQHQSHNRKQMLEQTSLVGRSELQNLSGQLHRANDSLCAKEEELETLKIQLRCAVEGQKRAEHETELSKQAVQALKEEKAELRATLQAHTEFLQGSRVQKHELLPEGYRGSEVLRENNSIRSVEERLQEMGQVGGETEVEAIRSKLSVSRMNEHRLQAEVTCLEDSVESVTSQCQLLAKELKGKEEYFHGVKEDHQKCLSENKKLKGQLSQAELTHKSVLDGMRKEISQLTQELHQRDIRMASSAGIDWERKIKAERQRAEREAAEHRMSLNALENLRQENCRLSELLQTQEPDVAQALVNLEQANQRLQRELLQTQEKLELIAQRRESEIQNAVDSISQELLNKQEQELRIMQERLKVYEQEMQTFRSQQDAASSGSSLESIFSEVWKEQATGSPISAASVDSAIEPVEDLASSLPVPPTSPANAVASRFLQEEEQRSHELLQRLNAHIEELKQESQRTVEHFTQAR", "length": 649, "molWeight": 75463, "crc64": "601BDA3CABC091C6", "md5": "2F63F57752A99BAC31EFBB90BE6D3E2D"}}
{"primaryAccession": "C0IW58", "text": "This is Low-redox potential peroxidase protein, from Poroid brown-rot fungus, contains 330 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C0IW58", "organism_name": "Poroid brown-rot fungus", "protein_name": "Low-redox potential peroxidase", "length": 330, "firstPublicDate": "2010-03-23", "FUNCTION": "Can oxidize the lignin redox mediator veratryl alcohol to veratryl aldehyde, May be involved in oxidation of lignocellulose substrates", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peroxidase family, Ligninase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRSSTHIFVSFVVYCGVFVTSAIALSNHTNAYQCDRWSNVLNELQANLFHEGQCRSAALRASGTFGGGGADGSIIQFAHTELAYPANEGLEEMVYTLKHFADGHEVSYGDMIQFAGAVALSNCPGSPRLRFYAGRPEAIAPSPPNLLPLPTDPVEKILSRMADAGFNAGDTVALLAAHSIAVQNTIDPSIPDSPLDSTPRIFDTQFYLETLLRGTRYPGKGRGPAQSKSPIEHEFRLASDAAIARHTSTACEWQSFIDNQEGLRSAFRNAMVKLANQGHDNLVDCSFVIPVPPPWNLPVEYPSGKSRSDVEQSCSDVPFPTISLNSDVHD", "length": 330, "molWeight": 35770, "crc64": "8F7D76BACF5CE1B3", "md5": "8452365C3EC8552F0B02F9101EE1C4A3"}}
{"primaryAccession": "C5J8E3", "text": "This is Sauvatide protein, from Sauvage's leaf frog, contains 62 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C5J8E3", "organism_name": "Sauvage's leaf frog", "protein_name": "Sauvatide", "length": 62, "firstPublicDate": "2010-03-02", "FUNCTION": "Induces contraction of smooth muscle in isolated rat urinary bladder with an EC(50) value of 2,2nM", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDILKKSLFLILFLGLVSISFCDGEKRQDDDEANESEEKKEIHEVEKRLRPAILVRTKGKGK", "length": 62, "molWeight": 7145, "crc64": "8E599AA948D3FCEC", "md5": "CA7167449A76C8E40A6118A5B0DE11A1"}}
{"primaryAccession": "C5P3X6", "text": "This is Extracellular metalloprotease 1 protein, from Valley fever fungus, contains 276 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C5P3X6", "organism_name": "Valley fever fungus", "protein_name": "Extracellular metalloprotease 1", "length": 276, "firstPublicDate": "2011-04-05", "FUNCTION": "Secreted metalloproteinase that allows assimilation of proteinaceous substrates, Pays a pivotal role as a pathogenicity determinant during infections and contributes to the ability of the pathogen to persist within the mammalian host, Digests an immunodominant cell surface antigen (SOWgp) and prevents host recognition of endospores during the phase of development when these fungal cells are most vulnerable to phagocytic cell defenses", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M43B family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRVSVPVLALAFGSLAAAAPNAGRRTCGSVPPPEFFEASEKVAALEESGAFADLQAPIEVETYFHVVASSRSERDGYISDQMLSDQIRVMNEDYAPHGVHFNLRETTRTINPSWASDGNEIAMKRSLRKGGYAALNVYFLKDLGGALGYCYFPTNAAPGSTTFIRDGCSVLSSSVPGGSGAPYDLGKTATHEVGHWMGLFHTFQGGCSGQGDYVSDTPPQRSPSSGCPVGRDSCPGGGVDPIHNYMDYSVDSCMNQFTRGQGTRMSSMWRQFRAGK", "length": 276, "molWeight": 29593, "crc64": "FD14BCC1770E22B8", "md5": "7DECCBC19171997CA95F0C8DCB7D56A1"}}
{"primaryAccession": "C6Y4C9", "text": "This is Sporulation-specific protein 13 protein, from Fission yeast, contains 138 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C6Y4C9", "organism_name": "Fission yeast", "protein_name": "Sporulation-specific protein 13", "length": 138, "firstPublicDate": "2009-11-24", "FUNCTION": "Involved in sporulation, Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMSNSQISKLFSSISNKENSNENALKESTNKQLNNANTLAITHLKEQLSREVQRREELEGLLEQSQKEMEDLSVSLFTEANEMVAKARQDTEVLKRELDYLRAKEKGRIGKLRSIQTAVRTSIEARKLLSYSNESNYH", "length": 138, "molWeight": 15862, "crc64": "3F037E23F0098696", "md5": "AD878FA7DAABD41E8AEEFEC42C2E3BDA"}}
{"primaryAccession": "D4AZ24", "text": "This is Glucan endo-1,3-beta-D-glucosidase ARB_01444 protein, from Trichophyton mentagrophytes, contains 909 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4AZ24", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Glucan endo-1,3-beta-D-glucosidase ARB_01444", "length": 909, "firstPublicDate": "2015-12-09", "FUNCTION": "Cleaves internal linkages in 1,3-beta-glucan (By similarity), Probably involved in cell separation after cytokinesis (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 81 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKPYTTLPGVAVLVSLLTQSAHAAPFPSRADVVHTREQESAARPQPIVYKHERGVSNEIQYLPPDPQGHPTIIPFPTHISYVTFNSRPGAIHPPYPHLDISEASFKAEDSTCWYRGKPCEGVPHIPIVKGFDSIEKRSPAPQRHPPAPTKATAGYQFTNCTSTSNPGPTATSPTSGIPSQPSAPPATMAGQDIFQPIAKDPIPANIKSRDDHPVKANHIENPTGPISTNKFYANFFLGNQTSTTFTHPYTMIWAKGDKNASSFGMAISHVEPSQRATGEPNNKLPGNPVRYYINPVGIKSLVLSASELKESTTMSVAKPQAFSAQAILRPTGGSSESITFPLVQGMGFITAIYNNLQPAIQSAVLFRKVEPAGSPQGGIFKYKITLEDDKNWLLYVIPENGADPKLKLEGNKLISGPTGFKGVIQVAKNPSAEEGEGIYDKSAGSYATDIKISGSVGTDGTGTYKFSFEKAGKGAPLVMYALPHHVESFDDATKNTKKNMKLSTTTKGMATACVGDSWTMVEGNLPLSMDFAPWKPGSSSQVTLSEGAKNAIKAVAGNELSQDMELQTNLNSMYFSGKGLNKFAGAIYTVQELVGDKAAASGPLNSLKESFKRFVDNKQQIPLVYDNVWKGVVSSGTYEKGDTGLDFGNTLYNDHHFHYGYFILTAAILGKLDPAWLDANKAYVNMLVRDSGNSVDNDEHFPFSRAFDWYHGHSWAKGLFESSDGKDQESTSEDTMYAYAIKMWGKTSGDKSMEARGNLMLGILARTLNNYFLMKNDNVNQPKNFIGNKVTGILFENKIDHTTYFGANLEYIQGIHMLPLLPNSAYTRSAEFVKEEWEAMFASGAAAPAEKVTGGWKGVLYANLAIIDPEASWKYFAQPSLDLSSIDGGASRIWYLAYAAGEYSTYIAL", "length": 909, "molWeight": 98853, "crc64": "178F24EFAD2C7C0C", "md5": "CF07F656408D180004BFFB8E1A1C5937"}}
{"primaryAccession": "D4N4Z9", "text": "This is Poly-cysteine and histidine-tailed protein protein, from Trichina worm, contains 424 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4N4Z9", "organism_name": "Trichina worm", "protein_name": "Poly-cysteine and histidine-tailed protein", "length": 424, "firstPublicDate": "2010-08-10", "FUNCTION": "Binds iron and zinc, May bind nickel", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFSTIVVLFVAAVGFGNKISSADTCPEFGEWKPWTECLWYPMQNIYDKMTASCGLPGHRNLTNILPLPPGFTIPPPCGHCSFKTRCRTRPKKEGCYPFDGEREICHEHGDICTIAKLPGIGCGWTVLQEVVKQCLSRPDIPEYMRAGYKKLFHMLPKGHCIEKDNQCKCCCGDYEPNEDGTECVKQQDHQCAPFNEPGDWSECLWFPLADMFKKVQSHCGVEGKPEGLSPSSLAPAGFQIPEKCGFCSFRLKCQSREKKEGCFPLKVDKKSCGAEDCPTCGDVCTLDKQNNSCAFTKAMGMKFWNSFAHKAKESNLAHWRRDGYADLFKFLPYGHCKEVGDKCKCCCHPYEPNEDGTACVVKQYCKSLEEVGGKKQQKDQPESEKKAENMPETTGNASHHQHRHHHGDSSSESHEQHHHHHHH", "length": 424, "molWeight": 47739, "crc64": "7018E80DF2DE72AE", "md5": "8AF5E4BF672E0D0B6C3F3535C63D82FD"}}
{"primaryAccession": "D8QLP9", "text": "This is 4-O-methyl-glucuronoyl methylesterase protein, from Split gill fungus, contains 393 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D8QLP9", "organism_name": "Split gill fungus", "protein_name": "4-O-methyl-glucuronoyl methylesterase", "length": 393, "firstPublicDate": "2016-04-13", "FUNCTION": "Glucuronoyl esterase which may play a significant role in biomass degradation, as it is considered to disconnect hemicellulose from lignin through the hydrolysis of the ester bond between 4-O-methyl-D-glucuronic acid residues of glucuronoxylans and aromatic alcohols of lignin", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the carbohydrate esterase 15 (CE15) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLSAALLAIAAFANVASAQDCDTPATVSGYSNSALPDPFTFNDGSPVTTAEDWECRRSQILALIQGYESGAAPPEPESVTGTASGNSLSVQVSYGGKSITFNNSITYPSGTAPAEGWPVIIAYEFPSLPIPSNVATLSFQNSAMGKQDSTSSRGQGLFYDLYGSSSNASAMTAWAWGVSRIIDAIESTPDAKLNPAAVGVTGCSRNGKGALMAGALEPRVALTLPQESGSGGDACWRLSRYEEQQGSQVQTATEIVGENCWFSAGFDQYVNNLDSLPYDHHLLAALVAPRGLISYANTDYVWLSGMSSFGCMTAAHAVYEALGVPENHGFEQVGGHSHCQWPSQLDGSLNAFINKFLLGQDVSTDYFESNNQFNGVTWSESQWINWETPTLN", "length": 393, "molWeight": 41773, "crc64": "4AEFD7FE7DD53993", "md5": "5BD35CE11374798EC741CF34EDA65902"}}
{"primaryAccession": "E7EKD0", "text": "This is Temporin-HN1 protein, from Odor frog, contains 62 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "E7EKD0", "organism_name": "Odor frog", "protein_name": "Temporin-HN1", "length": 62, "firstPublicDate": "2013-09-18", "FUNCTION": "Has antimicrobial activity against some Gram-positive bacteria and fungi but has no activity against a range of Gram-negative bacteria except P,faecalis, Active against the Gram-positive bacteria S,aureus ATCC 25923 (MIC=37,5 uM), S,carnosus KHS (MIC=37,5 uM), B,licheniformis X39 (MIC=19 uM), R,rhodochrous X15 (MIC=4,8 uM), is virtually inactive against E,faecalis 981 (MIC=150 uM) and inactive against E,faecium 091299, Has some antimicrobial activity against the Gram-negative bacterium P,faecalis X29 (MIC=75 uM) and is inactive against E,coli, P,aeruginosa and S,typhi, Has antifungal activity against C,albicans ATCC 2002 (MIC=19 uM) and lower activity against the slime mold 090223 (MIC=75 uM), Has low hemolytic activity against human erythrocytes (LC(50)=75 uM)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Temporin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTLKKSLLLLLFLGTINLSLSEQERNAEEERRDDPEEMDAEVEKRAILTTLANWARKFLGK", "length": 62, "molWeight": 7223, "crc64": "D9B4C6357BD7EDF3", "md5": "D17B024EB246F318B59075AD9863873F"}}
{"primaryAccession": "E7EKD4", "text": "This is Temporin-HN2 protein, from Odor frog, contains 59 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "E7EKD4", "organism_name": "Odor frog", "protein_name": "Temporin-HN2", "length": 59, "firstPublicDate": "2013-09-18", "FUNCTION": "Has antimicrobial activity against some Gram-positive bacteria and fungi but has no activity against a range of Gram-negative bacteria except P,faecalis, Active against the Gram-positive bacteria S,aureus ATCC 25923 (MIC=4,8 uM), S,carnosus KHS (MIC=19 uM), B,licheniformis X39 (MIC=19 uM) and R,rhodochrous X15 (MIC=2,4 uM) but is inactive against E,faecium 091299 and E,faecalis 981, Has a less potent antimicrobial activity against the Gram-negative bacterium P,faecalis X29 (MIC=37,5 uM) and is inactive against E,coli, P,aeruginosa and S,typhi, Has antifungal activity against C,albicans ATCC 2002 (MIC=9,5 uM) and is also active against the slime mold 090223 (MIC=9,5 uM), Has extremely low hemolytic activity against human erythrocytes (LC(50)=300 uM)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Temporin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTLKKSLLLLLFLGTINLSLSEQERDAKEERRDEMDVEVEKRNILNTIINLAKKILGK", "length": 59, "molWeight": 6873, "crc64": "27EC9FB8894381FB", "md5": "4F0E051F12CE7F68BA0C9DEB214D7D57"}}
{"primaryAccession": "F1LW30", "text": "This is Netrin receptor UNC5D protein, from Rat, contains 956 amino acids, has 1 Ig-like Immunoglobulin domain, has 1 Ig-like C2-type Immunoglobulin domain, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [{"location": [52, 149], "description": "Ig-like", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like Immunoglobulin domain"}, {"location": [164, 242], "description": "Ig-like C2-type", "keyword_description": "Immunoglobulin domain", "textural_description": "Ig-like C2-type Immunoglobulin domain"}], "meta_data": {"primaryAccession": "F1LW30", "organism_name": "Rat", "protein_name": "Netrin receptor UNC5D", "length": 956, "firstPublicDate": "2015-11-11", "FUNCTION": "Receptor for the netrin NTN4 that promotes neuronal cell survival, Plays a role in cell-cell adhesion and cell guidance, Receptor for netrin involved in cell migration, Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding, May play a role in apoptosis in response to DNA damage, It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity), Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the unc-5 family", "domain_description": {"Ig-like Immunoglobulin domain": 1, "Ig-like C2-type Immunoglobulin domain": 1}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGTGAADRSRGARWWLPWLGLCFWAAGAEAARGADSGEVLPDSIPSAPGTLPHFIEEPEDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEESLDESSGLKVREVFINVTRQQVEDFHGPEDYWCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTALCPVDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQRWSRRGIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSHSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNPAMHPDLTVSRTYSGPICLQDPLDKELMTESSLFNPLSDIKVKVQSSFMVSLGVSERAEYHGKNHSGTFPHGNNRGFSTIHPRNKTPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSEVLLSPEVTCGPPDMLVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWSSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQQDGDLDSLACALEEIGRTHTKLSNITEPQLDDTDFNYSRQNGL", "length": 956, "molWeight": 106520, "crc64": "E389EEE963CEE79E", "md5": "8A8E72AD925729BCF7367EA87DDE0DC5"}}
{"primaryAccession": "F2Z699", "text": "This is External alternative NADH-ubiquinone oxidoreductase, mitochondrial protein, from Yeast, contains 582 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F2Z699", "organism_name": "Yeast", "protein_name": "External alternative NADH-ubiquinone oxidoreductase, mitochondrial", "length": 582, "firstPublicDate": "2012-02-22", "FUNCTION": "Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the NADH dehydrogenase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRLRPAVRAVSVARSVALTRSLHVSVAKFNKIEGTAPAGLPKEVKQTAGHQGHHQEIPKPDENHPRRKKFHFWRSLWRLTYLSAIASLGYIGYRIYVIRNPSDQLPADPSKKTLVVLGSGWGSVSFLKKLDTSNYNVIVVSPRNYFLFTPLLPSCPTGTIEHRSIMEPIRGIIRHKQAECQYLEADATKIDHEKRIVTIRSAVSENSKEEVIKEIPFDYLVVGVGAMSSTFGIPGVQENACFLKEIPDAQQIRRTLMDCIEKAQFEKDPEVRKRLLHTVVVGGGPTGVEFAAELQDFFEDDLRKWIPDIRDDFKVTLVEALPNVLPSFSKKLIDYTEKTFSDEKISILTKTMVKSVDENVIRAEQTKGDGTKETLEMPYGTLVWATGNTVRPVVRELMSKIPAQKGSRRGLLVNEYLVVEGTEGIWALGDCSATKYAPTAQVASQEGSYLANLLNGIAKTEDLNNEITNLEKQSEHTFDEQERKNIFAQLESKSRKLRRSRAMLPFEYSHQGSLAYIGSDRAVADLSFNFWGIMNWSSGGTMTYYFWRSAYVSMCFSMRNKILVCIDWMKVRVFGRDISRE", "length": 582, "molWeight": 65815, "crc64": "2BD807DD0A026562", "md5": "389BC67FDF3FDDF419DA13AF775DD320"}}
{"primaryAccession": "F4I6M4", "text": "This is TORTIFOLIA1-like protein 1 protein, from Mouse-ear cress, contains 821 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4I6M4", "organism_name": "Mouse-ear cress", "protein_name": "TORTIFOLIA1-like protein 1", "length": 821, "firstPublicDate": "2011-09-21", "FUNCTION": "Plant-specific microtubule-associated protein (MAP) that regulates the orientation of cortical microtubules and the direction of organ growth", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRSQTASKTSMKPSSNSSAFSVRSSVAVSSHSAMVELKQRILTSLSRLGDRDTYQIAVDDLEKIVVSVPDSPEILPVLLHCLFDSSSDLKAPVKRESIRLLSFLCLSYTDLSFSQLAKIISHIVKRLKDADNGVRDACRDAIGSLSAQFLKEKEVENGNYVGSSLVGLFAKPLFEAMAEQNKSLQSGAAICMGKMIDSATEPPVAAFQKLCPRISKLLNSPNYITKASLLPVVGSLSQVGAIAPQSLESLLHSIHECLGCTNWVTRKAAADVLISLAVHSSSLVADKTDSTLTALEACRFDKIKPVRESLSEALNVWKNIAGKGESGTMDDQKDVSSEQCILERNGETDSVSCEEAGLVMQGSCDGLSSSSDSISKAVLILRKKAPRLTGKDLNPEFFQKLEKRGSGDMPVEVILPSRQKNSSNSNTEDESDANTSVLRSRSNGLCRTAGVHTKQRHFGDFAREKWVDERMNGGESRLRAFDGDHTEVIQADTSENRGNWPPLQRQLLHLERQQTHIMNMLQDFMGGSHDGMISLENRVRGLERIVEEMSREMSIQSGARGKATASWRSDVDGWDSPNYGPSSRNTQTSTRKIRGTGPSEQSGNSRRAWDKSSVAIRLGEGPSARSVWQASKDEATLEAIRVAGEDCGTSRNRRVSIPEAEAMMDEDDDNRGGQQGDPIWTCWSNSVHALRVGDTDSAFAEVLSTGDDHLLVKLMDKTGPVLDQLSSDMGNEAIHSIAQFLLDHTLYDICLSWIQQLLEVSVENGADFMGIPLELKKELLLNLHEALSTTDPPEDWEGLAPDHLLVELASNWNIEIQHFDT", "length": 821, "molWeight": 89945, "crc64": "519E33C37BD0D865", "md5": "CB2D54AC8B65A51B7A917C2E9C761711"}}
{"primaryAccession": "F4I8Q7", "text": "This is Vacuole membrane protein KMS2 protein, from Mouse-ear cress, contains 416 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4I8Q7", "organism_name": "Mouse-ear cress", "protein_name": "Vacuole membrane protein KMS2", "length": 416, "firstPublicDate": "2014-11-26", "FUNCTION": "Involved in the early secretory pathway, Required for the correct export of secretory products from the endoplasmic reticulum (ER) and involved in the maintenance of ER integrity", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the VMP1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGYGNRASSKTPAISGLREKHQQDLEKLTLTSQPFKTLRLFVVAVFLYVRRWSSYLLANVGWLILFCSIFVAFAALLVTLDGPHVKHVEELSEYTRFGLWWIFLGVASSIGLGSGLHTFVLYLGPHIALFTIKVMQCGRVDLKSAIYDTIQLKRSPSWLDKPCHEFGSPVFSSGVPLSSILPQVQIEAILWGLGTALGELPPYFISRAASLSGGKMKELETCSGDDNGFIAKRVNQIKSWLLSHSQYLNFFTILILASVPNPLFDLAGIMCGQFEKPFWEFFLATLIGKAIIKTHIQTVFIICVCNNQLLDWVENELIYILSFVPGFASALPELTAKLRLMKEKYLIASPPVSSDINVKKWDLSFASVWNGVVWLMLLNFFGQIVTSTAQRYLKKQQEEELDALTNKSSLTSKKSK", "length": 416, "molWeight": 46619, "crc64": "5E9A041B844F123A", "md5": "3628CC42A17166031CC0CBD0E8C84AEC"}}
{"primaryAccession": "F4K5W8", "text": "This is Sucrose synthase 5 protein, from Mouse-ear cress, contains 836 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4K5W8", "organism_name": "Mouse-ear cress", "protein_name": "Sucrose synthase 5", "length": 836, "firstPublicDate": "2012-09-05", "FUNCTION": "Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways, Functions in callose synthesis at the site of phloem sieve elements", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyltransferase 1 family, Plant sucrose synthase subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEMTSGSLGNGIPEAMGQNRGNIKRCLEKYIENGRRVMKLNELMDEMEIVINDVTQRRRVMEGDLGKILCFTQAVVIPPNVAFAVRGTPGNWQYVKVNSSNLSVEALSSTQYLKLKEFLFDENWANDENALEVDFGALDFTLPWLSLSSSIGNGLSFVSSKLGGRLNDNPQSLVDYLLSLEHQGEKLMMNETLNTARKLEMSLILADVFLSELPKDTPFQAFELRFKECGFEKGWGESAGRVKETMRILSEILQAPDPQNIDRFFARVPRIFNVVIFSVHGYFGQTDVLGLPDTGGQVVYILDQVKALEDELLQRINSQGLNFKPQILVVTRLIPDAKKTKCNQELEPIFGTKYSNILRIPFVTENGILRRWVSRFDIYPYLERFTKDATTKILDILEGKPDLIIGNYTDGNLVASLMANKLGITQATIAHALEKTKYEDSDIKWKEFDPKYHFSSQFTADLISMNSADFIIASTYQEIAGSKERAGQYESHMSFTVPGLYRVVSGINVFDPRFNIAAPGADDSIYFPFTAQDRRFTKFYTSIDELLYSQSENDEHIGYLVDKKKPIIFSMARLDVVKNLTGLTEWYAKNKRLRDLVNLVIVGGFFDASKSKDREEISEIKKMHSLIEKYQLKGQFRWITAQTDRTRNGELYRSIADTRGAFVQPAHYEAFGLTVIEAMSCGLVTFATNQGGPAEIIVDGVSGFHIDPSNGEESSDKIADFFEKSGMDPDYWNMFSNEGLQRINECYTWKIYANKVINMGSTYSYWRHLNKDQKLAKQRYIHSFYNLQYRNLVKTIPILSDIPEPPPLPPKPLVKPSASKGSKRTQPRLSFRLFGA", "length": 836, "molWeight": 94905, "crc64": "761DC9728DFDE252", "md5": "657A2B7976AD49E06C26CF4CAD10932C"}}
{"primaryAccession": "F4K6F1", "text": "This is Xyloglucan galactosyltransferase XLT2 protein, from Mouse-ear cress, contains 517 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F4K6F1", "organism_name": "Mouse-ear cress", "protein_name": "Xyloglucan galactosyltransferase XLT2", "length": 517, "firstPublicDate": "2016-04-13", "FUNCTION": "Functions in xyloglucan synthesis by adding side chains to the xylosylated glucan backbone, Involved in galactosylating hemicellulose xyloglucan (XyG) at the second position of the XXXG motif to form XLXG (PubMed:22474179), Associates with other xyloglucan-synthesizing enzymes to form multiprotein complexes for xyloglucan synthesis in the Golgi (PubMed:25392066)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the glycosyltransferase 47 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLPVSNPSSPEHLLKKSRTPDSTTSIDRKNSFNSLHSVGNRSSYIAASRSHCTWLILSLLSLQLILFLTLRSIPFPHRHIPENFPSPAAVVTTTVTTTVISAASSNPPLSSSSSDERCDSGRVFVYDMPKIFNEVILQQCDNLNPWSSRCDALSNDGFGQEATSLSNVIPKDLVQSWFWTDQFVTEIIFHNRILNHRCRTLDPESATAFYIPFYAGLAVGQYLWSNYAAADRDRHCKMMTQWVKNQPYWNRSNGWDHFITMGRITWDFRRSKDEDWGSNCIYIPGMRNITRLLIERNSWDHFDVGVPYPTGFHPRSDSDVVNWQDFVRNRRRETLFCFAGAPRAGIVNDFRGLLLRHCEESRGKCRTVDCTVGKCSNGSSAILETFLGSDFCLQPRGDSFTRRSIFDCMLAGSIPVFFWRRSAYMQYQWFLPDKPDSYSVFIDRNEVTNGTTSIKEVLERYSKEDVRKMRERVIDLIPNLVYAKSPNGLETFKDAFDVAIDGVFRRFKEQEKWYKWR", "length": 517, "molWeight": 59645, "crc64": "5CB6115C7A4DC0BC", "md5": "72CD3A38E06ACCCCB8A3679EE54DB8BB"}}
{"primaryAccession": "I2C092", "text": "This is Beta-mannosidase B protein, from Myceliophthora thermophila, contains 855 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "I2C092", "organism_name": "Myceliophthora thermophila", "protein_name": "Beta-mannosidase B", "length": 855, "firstPublicDate": "2014-03-19", "FUNCTION": "Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of beta-mannosidic oligosaccharides of various complexity and length, Prefers mannobiose over mannotriose, Is also severely restricted by galactosyl substitutions at the +1 subsite (By similarity), Has no activity against polymeric mannan", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 2 family, Beta-mannosidase B subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAPRVVIPLDQNWEFRQADKPDSKFLPVSQFPTNVHLDLQHHGLIPDPFIGKNELLVQWVGEAQWTYRTVFAAPPVPEGARAVIAFDGLDTFATVVLNGTTILESDNMFLPHRVEVTSVLKAEGNELVITFDSAYLRGCKLVEQHPNHKWGCWNGDVSRLAVRKAQYHWGWDWGPTLLTCGPWRPVHLEIYESRLSDLYAETVVDKSLKRASVKVTAVAERRADRVRFDIALDGQQVATETAELDATSGEATVSFLIDSPALWYPVRYGKQPLYDIRATLLAGDDEVDTLSKRIGLRRAELIQRPLEGQPGTSFFFEVNNIRIYCGGSDWIPADNFIPRISRRRYYDWVRLVAEGNQFMIRVWGGGIYEEQAFYDACDELGILVWQDFMFGCGNYPAWPALLESIRREATENVKRLRHHPSIVIWAGNNEDYQYQESEGLTYDYANKDAESWLKTDFPARYIYEKILADVCADLVPSTPYHPGSPWGAGLNTHDATVGDIHQWNVWHGTQEKWQNFDRLVGRFVSEFGMQAFPAVKTIDAYLPLGRDDPDRYPQSSTVDFHNKAEGHERRIALYLVENLRYAPDPLEHFVYCTQLMQGECLASAYRLWKREWRGPGREYCGGALVWQTNDCWPVTSWSIVDYYLRPKLAYFTVKREMAPVSIGITRRTHLHPRDRHTRVNVDVKTQIEVWASNLTLEDLTVDCVLKAWDVESGEETFSETVAAALLLRENRSTEIAALDVPVRQKNVGEEGRIVVAAYLVDKEGRQMARYVNWPEPLKYVHLQKPRALRAQLTADYSAVEVSAEVPVKGVALECEDDGVRFDDNLVDIVPGEVVTIGVSGAGKDTKIETRYLGMI", "length": 855, "molWeight": 97352, "crc64": "C90A3DB3050FEC9D", "md5": "A8D8AEEE74FD9188D6A6CE4E66E47D77"}}
{"primaryAccession": "M9P2C1", "text": "This is Tachykinin-like peptide protein, from Kwangsi warty tree frog, contains 91 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "M9P2C1", "organism_name": "Kwangsi warty tree frog", "protein_name": "Tachykinin-like peptide", "length": 91, "firstPublicDate": "2013-11-13", "FUNCTION": "Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles, In vitro, induces contraction of guinea pig ileum smooth muscle in a dose-dependent manner", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the tachykinin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKILVAFAVIMLVSAQVLAAEIGLNDEPEWYSDQIQEDLPVFENFLQRIARKPSPDRFYGLMGKRNNGFGQMSRKRSAERNTIHNYERRRK", "length": 91, "molWeight": 10658, "crc64": "1BD5DAB2C18CA5A2", "md5": "3BC659BCB7C120CACAB7E787D5A5E9D1"}}
{"primaryAccession": "O04193", "text": "This is LIM domain-containing protein WLIM2a protein, from Mouse-ear cress, contains 200 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O04193", "organism_name": "Mouse-ear cress", "protein_name": "LIM domain-containing protein WLIM2a", "length": 200, "firstPublicDate": "2014-10-29", "FUNCTION": "Binds to actin filaments and promotes cross-linking into thick bundles, Has an actin-stabilizing activity, The actin regulatory activities are not regulated by pH and [Ca(2+)]", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSFTGTQQKCRACEKTVYPVELLSADGISYHKACFKCSHCKSRLQLSNYSSMEGVVYCRPHFEQLFKESGSFSKNFQSPAKPLTDKPTPELNRTPSRLAGMFSGTQDKCATCTKTVYPIEKVTVESQCYHKSCFKCSHGGCPISPSNYAALEGILYCKHHFAQLFKEKGSYNHLIKSASIKRATAAATAAAAAVAAVPES", "length": 200, "molWeight": 21901, "crc64": "81CA8471F94B21DA", "md5": "0D44F7FA93ABB272E321C2BC04C03F83"}}
{"primaryAccession": "O04203", "text": "This is Nematode resistance protein-like HSPRO2 protein, from Mouse-ear cress, contains 435 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O04203", "organism_name": "Mouse-ear cress", "protein_name": "Nematode resistance protein-like HSPRO2", "length": 435, "firstPublicDate": "2011-07-27", "FUNCTION": "Positive regulator of basal resistance", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVDMDWKRKMVSSDLPNSPKLSSKLHVTIPSPFKIVPVSSPISCSAPALCSAYELYLRLPELRKLWSSRDFPQWTSEPILKPALQALEISFRLVFAVCSDTRPYINHREWNRRLDSLITKQIQLVAAICEDEEEEGISAEAPVGGGRSSLSLLPQLATWRRSEALGKKILYTIDNEMSRCKYTLGLGEQNIAGKPNLRYDAICRPNEIYSLKDNPYADHIDNHENQTLYIIHQILESWIYASGNLLNRIVSSIEEEKFGKASNDVYLLEKIWKILAEIEDLHMLMDPEDFLKLKKQLQIKSTGKNDAFCFRSKGLVEMMKMSKDLRQKVPAVLAVEVDPTGGPRLQEAAMKLYARKTECDKIHLLQGMQAVEAAAKSFFFGYRQLVAAMMGSAEMNATASQESCDSLSQIFMEPTYFPSLDAAKTFLGEFWSHLG", "length": 435, "molWeight": 49244, "crc64": "A0121598C4C751B1", "md5": "76BEA127FA30D5B09B37D5F4DD8448D7"}}
{"primaryAccession": "O04348", "text": "This is Thylakoidal processing peptidase 1, chloroplastic protein, from Mouse-ear cress, contains 340 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O04348", "organism_name": "Mouse-ear cress", "protein_name": "Thylakoidal processing peptidase 1, chloroplastic", "length": 340, "firstPublicDate": "2007-11-13", "FUNCTION": "Cleaves the thylakoid-transfer domain from a chloroplast protein", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the peptidase S26 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAIRITFTYSTHVARNLVGTRVGPGGYCFESLVRPRFFSHKRDFDRSPRNRPASMYGSIARELIGEGSQSPLVMGLISILKSTTGHESSTMNVLGVSSFKASSIIPFLQGSKWIKNPPVIDDVDKGGTVCDDDDDKESRNGGSGWVNKLLSVCSEDAKAAFTAVTVSILFRSALAEPKSIPSTSMYPTLDKGDRVMAEKVSYFFRKPEVSDIVIFKAPPILLEYPEYGYSSNDVFIKRIVASEGDWVEVRDGKLFVNDIVQEEDFVLEPMSYEMEPMFVPKGYVFVLGDNRNKSFDSHNWGPLPIENIVGRSVFRYWPPSKVSDTIYHDQAITRGPVAVS", "length": 340, "molWeight": 37853, "crc64": "F6763EBFC1DAA2E1", "md5": "21576DE30A8B6F6762420A45F2F1F62D"}}
{"primaryAccession": "O11780", "text": "This is Transforming growth factor-beta-induced protein ig-h3 protein, from Pig, contains 683 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O11780", "organism_name": "Pig", "protein_name": "Transforming growth factor-beta-induced protein ig-h3", "length": 683, "firstPublicDate": "2000-05-30", "FUNCTION": "Plays a role in cell adhesion (By similarity), May play a role in cell-collagen interactions (PubMed:9061001)", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALLGRLLPLALALALGPAATHAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKLIGTNKKYFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAVLPLSNLYETLGVVGSTTTQLYTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVDRRVLTDELKHGMALTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTVTNNIQQIIEIEDTFETLRAAVAASGLNTLLEGDGQYTLLAPSNEAFEKIPAETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSLETLEGTTLEVGCSGDMLTINGKPIISNKDVLATNGVIHFIDELLIPDSAKTLFELAAESDVSTAVDLFRQAGLGSHLSGNERLTLLAPMNSVFKDGTPRIDARTKNLLLNHMIKDQLASKYLYHGQTLDTLGGKKLRVFVYRNSLCIENSCIAAHDKRGRYGTLFTMDRMLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVFAPTNEAFQALPLGERNKLLGNAKELANILKYHVGDEILVSGGIGALVRLKSLQGDKLEVSSKNSLVTVNKEPVAEADIMATNGVVHTINTVLRPPANKPQERGDELADSALEIFKQASAFSRATQSSVKLAPVYQRLLERMKH", "length": 683, "molWeight": 74462, "crc64": "B4033E75D1C82A77", "md5": "4B805CD89033B1D1A573477325593149"}}
{"primaryAccession": "O13701", "text": "This is Transcription initiation factor TFIID subunit 7 protein, from Fission yeast, contains 393 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13701", "organism_name": "Fission yeast", "protein_name": "Transcription initiation factor TFIID subunit 7", "length": 393, "firstPublicDate": "2002-12-06", "FUNCTION": "TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription, Also involved in the transport of mRNA from the nucleus to the cytoplasm", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TAF7 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVKLKIRAVQPPPNDSRSSTPATGPPPPIPKIKIKTREPKGPRLTKIRLKRVREPGLGYDSEASDREEDTYIEEQIILRLPPGEDCEYVRKAIENREVGRGADIWVKFKDQRRAVVHVNGHLYAAKLVDLPCIIESNKSFDKKVIFKAADICQMLIATERIEHENSVLNTQLKQADYIYPHGLTTPMHWVRQKRFRKRVSNRTIEAVENEVDRLLAMDERAESTSNELIDQAQLARDSSIALSEDTSFDGMAGLRGTSIDRDDQSVQTDMFDGMDEDDLAGQIEQGMLELSQDTRESTAEPRAAGEESASEEEEEEEEEEEEENEADDETRENKRQNRLVREFISELESSIQKRRKDADEATNPILRNRFLADVNRMVTELELKRTQLVDNPE", "length": 393, "molWeight": 45000, "crc64": "58234FBA16998B5B", "md5": "1B7F6F18317D7B20E40001F94D0400EF"}}
{"primaryAccession": "O13713", "text": "This is Nuclear polyadenylated RNA-binding protein nab2 protein, from Fission yeast, contains 307 amino acids, has 3 C3H1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [178, 202], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [217, 232], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [254, 268], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "O13713", "organism_name": "Fission yeast", "protein_name": "Nuclear polyadenylated RNA-binding protein nab2", "length": 307, "firstPublicDate": "2008-11-04", "FUNCTION": "Binds to polyadenylated RNA and single-stranded DNA, It may be involved not only in RNA processing but also in transcription regulation, Believed to associate directly with nascent RNA polymerase II transcripts and remain associated during subsequent nuclear RNA processing reactions (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the NAB2 family", "domain_description": {"C3H1-type Zinc finger": 3}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTTLLETPGYSEKLHDSIEKKLSEYGWGEEAASLADFVLVMLSNGKTQTEINEELVDLIGSDFDTSFSLWLFNQIEELEKSKNASVESVSKIDEIDFIEKESTDKSQQSFSVPETSIQPQSSQTPNITSLREEKELPTGRVGQKLKLTSQKQRFNPMAASFNYSKSVMPAAKRALTQTQEVPLCKYADKCSRANCIFAHPTPAAAPGEGMVLSSEMCASGKECKAADCVKGHPSPATVTTLPPFMSMSTIPIPCKYKPCLNPACRFIHPTKSRNMTWRPPSKTEETSLSERSFAVNESEEQLHVPSV", "length": 307, "molWeight": 33929, "crc64": "7DC0907D588F05DE", "md5": "05C4D7A5AED235E6232AFEBA9F4FC1B5"}}
{"primaryAccession": "O13846", "text": "This is Ceramide very long chain fatty acid hydroxylase scs7 protein, from Fission yeast, contains 347 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13846", "organism_name": "Fission yeast", "protein_name": "Ceramide very long chain fatty acid hydroxylase scs7", "length": 347, "firstPublicDate": "2009-02-10", "FUNCTION": "Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids, Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the sterol desaturase family, SCS7 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASVTSEKCVILSDGTEYDVTNYLVANKDAADLLRRYHRQEVADILNATSKSKHSEAVVEILKSAKVPLKNKEFSDLVDQNIGVGYGNEFIVKPTDLDKDFEKNHFLDLKKPLLPQILFGNIKKDVYLDQVHRPRHYRGSGSAPLFGNFLEPLTKTPWYMIPLIWVPCVTYGFLYACTGIPFSVAITFFIIGLFTWTLVEYTMHRFLFHLDEYTPDHPIFLTMHFAFHGCHHFLPADKYRLVMPPALFLIFATPWYHFIQLVLPHYIGVAGFSGAILGYVFYDLTHYFLHHRRMPNAYLTDLKTWHLDHHYKDYKSAYGITSWFWDRVFGTEGPLFNEQGKISTKAK", "length": 347, "molWeight": 40229, "crc64": "B713353AC6FFB251", "md5": "222003E73171998C9692413DAAD255BC"}}
{"primaryAccession": "O14104", "text": "This is Homoisocitrate dehydrogenase protein, from Fission yeast, contains 362 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14104", "organism_name": "Fission yeast", "protein_name": "Homoisocitrate dehydrogenase", "length": 362, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSATRRIVLGLIPADGIGKEVVPAARRLMENLPAKHKLKFDFIDLDAGWGTFERTGKALPERTVERLKTECNAALFGAVQSPTHKVAGYSSPIVALRKKMGLYANVRPVKSLDGAKGKPVDLVIVRENTECLYVKEERMVQNTPGKRVAEAIRRISEEASTKIGKMAFEIAKSRQKIRESGTYSIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYASINVDEQIVDSMVYRLFREPECFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGDNFVMSEPVHGSAPDIAGRGIANPVATFRSVALMLEFMGHQDAAADIYTAVDKVLTEGKVLTPDLGGKSGTNEITDAVLANIHN", "length": 362, "molWeight": 39256, "crc64": "85865AFD69BCE773", "md5": "4A1F9AD4E168A0A986C5035486A3E622"}}
{"primaryAccession": "O14154", "text": "This is Alpha-amylase mde5 protein, from Fission yeast, contains 513 amino acids, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14154", "organism_name": "Fission yeast", "protein_name": "Alpha-amylase mde5", "length": 513, "firstPublicDate": "1998-07-15", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyl hydrolase 13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKHNEVFGWTLKVLSFLLVVIPANALDKHGWRKQSIYSLLTDRFASTNPKPCNPEDREYCGGNWRGIIDKLDYIQGMGFTAIWISPIIKNIEGRTKYGEAYHGYWPQDLYTLNPHFGTEQDLIDLADALHDRGMYLMVDTVVNHMGSSDPRNIDYGIYRPFNQSSHYHPMCPIEQDKPLSLEQCWIGTEDMTLPDIDTENPQIIETLYNFIHDQVKQFKIDGLRVDATKHVRRTFWPGFCESAGVYCQGEEWTGQADLFCEWQEYMDGLHNFPVQGVAAESVIPLNDRALRKTAIAMNLVAHHCKDSTLLGLFLESQDAPRLAALNNDYTVLKNAMTLNLMSDGIPIVFYGQEQMFNGSHDPVNRPALWDQGYNTDGPLYQYTSKVNKIRRDLINSEDGEIYIRSITHAIMIGDHVMVMYKGPVITFITNYGAVDKEYLIKMPGSETMIDLLTCTLIEVEGEVMRTSIKKGEPKILYPYQLAFRDGFCQEQITLQEIDDVFMGRNEINGPDRK", "length": 513, "molWeight": 58716, "crc64": "455DD97FA428C182", "md5": "71711AB114D83475D8308B63AAA96547"}}
{"primaryAccession": "O14275", "text": "This is Pentatricopeptide repeat-containing protein 4, mitochondrial protein, from Fission yeast, contains 931 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14275", "organism_name": "Fission yeast", "protein_name": "Pentatricopeptide repeat-containing protein 4, mitochondrial", "length": 931, "firstPublicDate": "2008-02-05", "FUNCTION": "Mitochondrial RNA-binding protein that specifically activates the translation of the cox1 mRNA", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSKSFAYRHIWCFWRFNTPLLWFPQPLKYWPAFQQSHTFNSMSVFKNDNAIANQTTVNESDVKRNVEKINDIYECSNNTKSPCFPNSDSRIPLVNWKTSTNPTLQVRAYMLDLLLPFFTLDLLPFLNKVCECCNHMLLDNPKIKQDLPFAFCYLFSSYFSYKSSRQYTCSSEEISKVFRHLNRLGGSEYVLHLFAQIPKALCKELTDVRTLNHPLRSIFTFCFKNISNPPNLLKLLTKLYPRSDRANEVLYTQYLGFLTKRGDYQIAIYMFDEMYRTHHWSSFTACRLMIESLVRQNKFEEAISLYKKIIAKRPKIARDKKILNLLLYISTVSNRSPDAFKLALQSISNANQIPSFDVFSRLMSALVKYNMTEMILPLVKQYDHKFRNLYSPNIFLSIVQALVFCGDMVNIQRWYNMSRVNSELSRIKHLLNCFLNSSTVSLDVSMVLELLRDLKKKKIKVDERTLVICITIFSRRKDLFAMEKIHQYFSDQGIKTSNQAYAALLDAYIEAEDTEKIELYLGKIRRLGITEDVSINRMLMRLALDRLDWDLLEQCTKVAERKDPEGQDYLSTITMLYHVRQHELNLALRIFSGIQKPNVVHYSIAATVLGNLNQLDQLLLLEKRMESEGKAPTALSLVAFVSSYCKQGAEGLDEAKRYMSKNFQPDKRALLFNPRTANDMTYPPSLFSSLIKEYTSLGDIKEAKQVLSTYLEYFSKNITSKPDIPFAIASMRLYCSLHDTVLSRQFWDLILQVAQQNFITTDIAAVVDDKNIPSPSGVIPAYKSALNVAAETYFSFLASVNSFQELDQEWSRLEKLGFEYDDSLQNKRIIWLLYDDRLDAAIKRVYNIFLSSKRIEELIPDASSQNSIISFFLSPDSPLYFSTLKALRDKLDMAVEDDFVRISQGILVPTVKYLQTIRRDNEILFNLLAKV", "length": 931, "molWeight": 107984, "crc64": "D46AA3D7E40B46ED", "md5": "800653B845A9957F7A10B2EDDCAFC263"}}
{"primaryAccession": "O14311", "text": "This is SAGA complex subunit spt3 protein, from Fission yeast, contains 307 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14311", "organism_name": "Fission yeast", "protein_name": "SAGA complex subunit spt3", "length": 307, "firstPublicDate": "2001-01-11", "FUNCTION": "Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA, SAGA is involved in RNA polymerase II-dependent transcriptional regulation, At the promoters, SAGA is required for recruitment of the basal transcription machinery, It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (spt3, spt8 and spt20) and promoter selectivity, interaction with transcription activators (gcn5, ada2, ada3 and tra1), and chromatin modification through histone acetylation (gcn5) and deubiquitination (ubp8), SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac), SAGA interacts with DNA via upstream activating sequences (UASs), Spt3 is required for recruitment of TATA-binding protein (TBP) to SAGA-dependent promoters, During SAGA-mediated transcriptional inhibition, spt3 and spt8 prevent binding of TBP to the TATA box (By similarity), SPT factors 3, 7 and 8 are required for the initiation of Ty transcription from the delta promoter, Spt3 regulates Ty1 as well as the mating factor genes", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SPT3 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTETGRTSKYRVEIQQMMFILGEVQDPLPETTQLVEELIRGQVMEMLIQANELALRRGSRSITVEDLFFLIRHDRAKVNRLKTYLSWKEVRKKAKEQDANPADTKDLFEEVDSKTRSMNAVAMPWEVKNMFTEPVPETEEFEEDNDTMEMAYATRQRLKMADERTKKMTREEYVHWSECRQASFTYRKGKRFREWCGMSILTDTRPDNDIVDILGFLTFEIVATLTEEALAVKDRMDRIQNSSGSGGSHAAHHPKNCSLFDGLTEGRTPLQVSHVLEAFRRLQIPDKTHTAMRSFHGGLVKSRVYLI", "length": 307, "molWeight": 35633, "crc64": "AB868458D651CC04", "md5": "4C3F2D59ADD126D4DA3F91A6D6291E29"}}
{"primaryAccession": "O22160", "text": "This is Thylakoid lumenal 15 kDa protein 1, chloroplastic protein, from Mouse-ear cress, contains 224 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O22160", "organism_name": "Mouse-ear cress", "protein_name": "Thylakoid lumenal 15 kDa protein 1, chloroplastic", "length": 224, "firstPublicDate": "2001-09-26", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVILSNVSLFSCCNISQKPSLFSPSSRSSHCPIRCSQSQEGKEVVTSPLRSVVWSLGEEVSKRSLFALVSASLFFVDPALAFKGGGPYGQGVTRGQDLSGKDFSGQTLIRQDFKTSILRQANFKGAKLLGASFFDADLTGADLSEADLRGADFSLANVTKVNLTNANLEGATVTGNTSFKGSNITGADFTDVPLRDDQRVYLCKVADGVNATTGNATRDTLLCN", "length": 224, "molWeight": 23779, "crc64": "ABCECC58F04ADEE4", "md5": "DF5A7B09A9C271BCDEB52ED880CD45CA"}}
{"primaryAccession": "O22241", "text": "This is Arogenate dehydratase 4, chloroplastic protein, from Mouse-ear cress, contains 424 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O22241", "organism_name": "Mouse-ear cress", "protein_name": "Arogenate dehydratase 4, chloroplastic", "length": 424, "firstPublicDate": "2009-05-05", "FUNCTION": "Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQAATSCDLKFRSTDPTSRNKCFSHAIPKRVAVTCGYRSESFSFPNGVSVSRSDWQSSCAILSSKVASVENTGGLADKIAAVNGHTNGSVNLGLVAVESTNGKLAPAQPLTITDLSPAPLHGSSLRVAYQGVPGAYSEAAAGKAYPNCDAIPCDQFDVAFQAVELWIADRAVLPVENSLGGSIHRNYDLLLRHRLHIVGEVQIPVHHCLLALPGVRTDCVSRVISHPQALAQTEHSLDVLTPHAAREAFHDTAAAAEYISANDLHDTAAVASARAAELYNLQILADGIQDDPGNVTRFLMLAREPIIPRTDRPFKTSIVFAAQEHKGTSVLFKVLSAFAFRDISLTKIESRPHHNRPLRVVGDGSFGTSKNFEYMFYVDFEASMAEPRAQNALAEVQEYTSFLRVLGSYPMDMTPWSMTSTEEA", "length": 424, "molWeight": 45925, "crc64": "B12A05BE6C0A0D24", "md5": "A736FEFBC2A2915675DCE171E94FACC1"}}
{"primaryAccession": "O23342", "text": "This is Preprotein translocase subunit SECE1 protein, from Mouse-ear cress, contains 177 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O23342", "organism_name": "Mouse-ear cress", "protein_name": "Preprotein translocase subunit SECE1", "length": 177, "firstPublicDate": "2011-12-14", "FUNCTION": "Involved in the import/insertion pathway in the thylakoids, The signal recognition particle is not involved in the insertion of SECE1 in the thylakoid membrane", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the SecE/SEC61-gamma family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSLTAQFSPPVTGITRSLRDTKPSLSNLRVFPVYTEIRTMTTSNLRKSACFVAKAIEQRRDTAGSESESEATPSPAEESGSGEDKEVEISAIGAEIKAAMEQRKTAEEEKGKNEFLSGVAEEVKEIEWPAFQKVLGTTGVVLGVIAGSSVVLLTVNFLLAELSDRVFIGRGVQDFFS", "length": 177, "molWeight": 19121, "crc64": "31401FAB30BBA8C8", "md5": "545C72177BC0C9D95AC57D66A616F661"}}
{"primaryAccession": "O35586", "text": "This is Isopentenyl-diphosphate Delta-isomerase 1 protein, from Golden hamster, contains 227 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O35586", "organism_name": "Golden hamster", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "length": 227, "firstPublicDate": "2000-05-30", "FUNCTION": "Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the IPP isomerase type 1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPEINTSHLDEQQVQLLAEMCILIDENDNKIGADTKKNCHLNENIDKGLLHRAFSVFLFNTENKLLLQQRSDAKITFPGCFTNSCCSHPLSNPGELEENDAIGVKRAAQRRLKAELGIPLEEVDPNEMHYLTRIYYKAQSDGIWGEHEIDYILFLKKNVTLNPDPNEIKSYCYVSKEELKELVKKAASGEVKLTPWFKIIVDTFLFKWWDNLNHLSQFVDHEKIHRM", "length": 227, "molWeight": 26317, "crc64": "F500A6586385E803", "md5": "CFF05D2C7EE4E4F0BB58E16860DD2E73"}}
{"primaryAccession": "O42602", "text": "This is Corticotropin-releasing factor receptor 1 protein, from African clawed frog, contains 415 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42602", "organism_name": "African clawed frog", "protein_name": "Corticotropin-releasing factor receptor 1", "length": 415, "firstPublicDate": "1998-07-15", "FUNCTION": "G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin), Has high affinity for CRH and UCN, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase, Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLLAKTPCLLLVQVIAAGISFALTSLQDQCETLQHNSNFTGLACNASIDMIGTCWPSTAAGQMVARPCPEYFHGVQYNTTGNVYRECHLNGSWAGRGDYAQCQEILKQEKKTKVHYHIAIVINFLGHSISLCALLVAFILFLRLRSIRCLRNIIHWNLITAFILRNVTWFVMQLTLSHEAHDSNVVWCRLVTIAHNYFYVTNFFWMFGEGCYLHTAIVLTYSTDKLRKWMFICIGWCIPFPIIVAWAIGKLYYDNEKCWFGKKAGVYTDFIYQGPVILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVTPGEDEISRIVFIYFNSFLQSFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRARVARAMSIPTSPTRISFHSIKQSSAI", "length": 415, "molWeight": 47786, "crc64": "74ED24C17907B74D", "md5": "3497610C16C8F2FCEB8D7F0A78B57111"}}
{"primaryAccession": "O42955", "text": "This is Pentatricopeptide repeat-containing protein 3, mitochondrial protein, from Fission yeast, contains 687 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42955", "organism_name": "Fission yeast", "protein_name": "Pentatricopeptide repeat-containing protein 3, mitochondrial", "length": 687, "firstPublicDate": "2008-02-05", "FUNCTION": "RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts, Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the CCM1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLNKCSGSLTLLAVRRFCGPCRRLHYHKDNPNNINIAKNLLNNNIQARCSTNEASWKLAQKELDLKIREYEQKLKDVKLNDINKKSPLNIPDEVWTKFISEVNSYDKEKENHLSTGNHELRRTTPLKIGPLLLTRIGLLKSKNTASNNYSVDHIVSNLANDNTLLNRQVSTEEWNSHLRHLLNIPKCFLGVDIVEIVNFFNYLPQTVISKSSLEIWKAVEESGMKVMPDLLVLLMESTNASGDFRKTVQLYHLYQKSNAPPNGLVYQSYAIALSSLGKHKDLVALYSEQKSVSITPSKDFLNACIKAFSRTKEFTKAWEVFNFMKFTATSISPSAETYGLMIQICSSQYNPEKALDLYNEMKLRPIDPLTPTTFVINNLIHALATDVRFQTVAFSLLQDLSHYGLRPNHSTLYELIRLIAYSGKLDYMKDILDNFWVRQKLLPSILKVEQIFHFIFRALISAEVQTSSVTPDYTHFKEEVRKIIDSSKEPLIPFLKRSTLTENDLFLNAIYTFEYAKRKFPEALNSRLVTDFLNIFLERGSVQLFKEIYQLEFREMSTMEGSSMKVAKITLTYIYAIKLALLFNDFEFGYAAWQEYWHCKIHKLLPKEDASYEQKVVLLTLSLLSKNKHTSLARSLLLSHLDKGWTWNKHSLGFMRKMCSVMNDQATVYLIDSITNEIGINQRFTRK", "length": 687, "molWeight": 79293, "crc64": "59B30E970ED0F77C", "md5": "E6FE51335E246B74E30E225B489E0E81"}}
{"primaryAccession": "O42956", "text": "This is Arrestin family protein 1 protein, from Fission yeast, contains 483 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42956", "organism_name": "Fission yeast", "protein_name": "Arrestin family protein 1", "length": 483, "firstPublicDate": "2007-09-11", "FUNCTION": "Involved in cytokinesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the arrestin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTSPCTLIRQFSPLEIRPLPHLDFQAGFNGIPTSAPRLVGIVQVRSKEIHQPLALVQITLELWKIESVVIPSLGISNHLSDNKCLARQVLFPLHSEHPENNIPPNDNNYSISDLSIKSPPPSLTSDWIVDSYASDQDNPSVHTHNRTTPPIPPPHLPNASGSSVYQPPYTPFRSVSTTSSSNDTSITPFGDQTPILSSSSDPYATHRVWSMDLPFEIPFPENSEIPSTFELNRSGTICSTKYELRAHMSLLGVPDITTTVPVSLSRYDNLSSWGMYNSPTNIRQVSSDGRVVVEVSIPKLCIGPSDLVSVFVSIMPNNGSKIRVQQLSLSLVEYITFIHPSSSSPIVRKKKVLRYEEDLDDMKLTSEGLSKSLSKPFPDIDFEDANITGFTTTSDLYSVQYMLVIKVQLYRARNIEITNPIIVSPVERSRSQALLNEIQTRVLDVRQSHGGVVLEENVRIVRASDFSKNNMFAYLNDDIVLLS", "length": 483, "molWeight": 53711, "crc64": "74F8FAC7FAE1807A", "md5": "87C50E131BE37A5317FC6C2859511D0F"}}
{"primaryAccession": "O43050", "text": "This is Sterol-4-alpha-carboxylate 3-dehydrogenase erg26, decarboxylating protein, from Fission yeast, contains 340 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O43050", "organism_name": "Fission yeast", "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase erg26, decarboxylating", "length": 340, "firstPublicDate": "2008-12-16", "FUNCTION": "Sterol-4-alpha-carboxylate 3-dehydrogenase; part of the third module of ergosterol biosynthesis pathway that includes by the late steps of the pathway (By similarity), Erg26 is a catalytic component of the C-4 demethylation complex that catalyzes the oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group (By similarity), The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane, Firstly, the squalene synthase erg9 catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids, Secondly, squalene is converted into lanosterol by the consecutive action of the squalene epoxidase erg1 and the lanosterol synthase erg7, The lanosterol 14-alpha-demethylase erg11/cyp1 catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol, In the next steps, a complex process involving various demethylation, reduction and desaturation reactions catalyzed by the C-14 reductase erg24 and the C-4 demethylation complex erg25-erg26-erg27 leads to the production of zymosterol, Erg28 likely functions in the C-4 demethylation complex reaction by tethering erg26 and Erg27 to the endoplasmic reticulum or to facilitate interaction between these proteins, Then, the sterol 24-C-methyltransferase erg6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol, The C-8 sterol isomerase erg2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol, The sterol-C5-desaturases erg31 and erg32 then catalyze the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol, The C-22 sterol desaturase erg5 further converts 5-dehydroepisterol into ergosta-5,7,22,24(28)-tetraen-3beta-ol by forming the C-22(23) double bond in the sterol side chain, Finally, ergosta-5,7,22,24(28)-tetraen-3beta-ol is substrate of the C-24(28) sterol reductase erg4 to produce ergosterol (PubMed:18310029) (Probable), In the genus Schizosaccharomyces, a second route exists between lanosterol and fecosterol, via the methylation of lanosterol to eburicol by erg6, followed by C14-demethylation by erg11/cyp1 and C4-demethylation by the demethylation complex erg25-erg26-erg27 (PubMed:8586261) (Probable)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the 3-beta-HSD family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPMNSVLVIGSGFLGGHIIRQLCERENLRIAAFDLFENEKLLHELHGQFTMYTGDLTKQGDIERVFEEFHPRVVIHTASPVHNLARDIYFEVNVDGTANIIKACQKFNVDALVYTSSAGVVFNGADLINVDESQPIPEVHMDAYNESKALAEKQVLEASSESLKTAALRVAGLFGPGDRQLVPGMLSVLKNGQTKFQLGDNLNLFDFTYIENAAYAHLLAMDNLLSSNPTANGQVFFITNGQVIYFWDFARAIWAHAGHVPPYIIKFPRPVGMLLATAAEWVCYFLKKEPGFTRFRVQFSCANRYFNIQKAEDVLKYHPIVDLEEGIRRTLAWMDTEKKH", "length": 340, "molWeight": 38318, "crc64": "493ADB21D10E7B50", "md5": "135DA92D6EE5A9EFB62DB2C7D71FC3AD"}}
{"primaryAccession": "O43071", "text": "This is Pre-mRNA-processing factor 17 protein, from Fission yeast, contains 558 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O43071", "organism_name": "Fission yeast", "protein_name": "Pre-mRNA-processing factor 17", "length": 558, "firstPublicDate": "2007-02-20", "FUNCTION": "Functions in the second step of pre-mRNA splicing, Involved in splicing intron which are longer than 200 nucleotides", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLVANYSSDSEEQENSQSPNIQPLLHTENLAPAVVDNVKDDLIVSKGGNSRELARNVPVNEMVQPALGPANPFVTKEQDSIKNSITGYAEREYVPNFVFNQEYYANTHAIYGKRNFDDNEATTSTDLKRKSQKIKERREDPGDPSILEGDGAYKGPWAGYGSEQSSSPLEYSEYEEVESLDVKSEKDTESNNLGQNELLKEQLATPEVETHRSKEETILHKDRLFDYQNRSYMHVPNDVGINLSEEPGEQTCYIPKKHIFTWKGHTKGISCLRFFPISGHLLLSGSMDNQIKIWEVYHDRSLLRTFQGHARPIRDLSFSQDGRSFLSTSFDKTIKLWDTELGKCLNCFNSDRLTNCVKFQVDPDKPNEFLAGTADKRILQFDIRSPDIVQAYDHHLGGINSITFLENGKRFVTTSDDSSMRFWEYGTPVPIKFVADIAMHSMPRVALRPNGKSIACQSLDNCIYVYSAYEKYRQNKKKVFKGYSCSGYSLEVGFSPDGRFVFSGDSSGNACFWDWKTCKLMAKLPAHSGPVQSMAFHPQETSKVATSSIVDGSIKYWD", "length": 558, "molWeight": 63132, "crc64": "78859607D4460195", "md5": "A88C6EC49D96A413732BAE02B01C3585"}}
{"primaryAccession": "O46028", "text": "This is Potassium channel toxin alpha-KTx 10.1 protein, from Mexican scorpion, contains 62 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O46028", "organism_name": "Mexican scorpion", "protein_name": "Potassium channel toxin alpha-KTx 10.1", "length": 62, "firstPublicDate": "2001-12-19", "FUNCTION": "Blocks Shaker B (Sh) and voltage-gated potassium-channels Kv1,1/KCNA1, Kv1,2/KCNA2, Kv1,3/KCNA3, Also inhibits small conductance calcium-activated potassium channels (KCNN) and intermediate conductance calcium-activated potassium channel (KCa3,1/KCNN4)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 10 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEGIAKITLILLFLFVTMHTFANWNTEAAVCVYRTCDKDCKRRGYRSGKCINNACKCYPYGK", "length": 62, "molWeight": 7131, "crc64": "32CEAE093B6971A0", "md5": "4B718B0A21C489945BA05FDE805624CE"}}
{"primaryAccession": "O48845", "text": "This is Cytochrome b5 isoform B protein, from Mouse-ear cress, contains 134 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O48845", "organism_name": "Mouse-ear cress", "protein_name": "Cytochrome b5 isoform B", "length": 134, "firstPublicDate": "2001-01-11", "FUNCTION": "Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases, including fatty acid desaturases", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the cytochrome b5 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGDEAKIFTLSEVSEHNQAHDCWIVINGKVYNVTKFLEDHPGGDDVLLSSTGKDATDDFEDVGHSESAREMMEQYYVGEIDPTTIPKKVKYTPPKQPHYNQDKTSEFIIKLLQFLVPLAILGLAVGIRIYTKSG", "length": 134, "molWeight": 15016, "crc64": "B405F5430F5716C1", "md5": "FABC527A7DF774C5B276D28F3C08F6A1"}}
{"primaryAccession": "O48916", "text": "This is Dihydroceramide fatty acyl 2-hydroxylase FAH1 protein, from Mouse-ear cress, contains 237 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O48916", "organism_name": "Mouse-ear cress", "protein_name": "Dihydroceramide fatty acyl 2-hydroxylase FAH1", "length": 237, "firstPublicDate": "2012-10-03", "FUNCTION": "Fatty acid 2-hydroxylase involved in the alpha-hydroxylation of sphingolipid-associated very long-chain fatty acids (VLCFA), Probably involved in the resistance response to oxidative stress", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the sterol desaturase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVAQGFTVDLKKPLVFQVGHLGEDYEEWVHQPIATKEGPRFFQSDFWEFLTLTVWWAVPVIWLPVVVWCISRSVSMGCSLPEIVPIVVMGIFIWTFFEYVLHRFVFHIKTKSYWGNTAHYLIHGCHHKHPMDHLRLVFPPTATAILCFPFWNIAKAISTPSTAPALFGGGMLGYVMYDVTHYYLHHAQPTRPVTKNLKKYHLNHHFRIQDKGFGITSSLWDIVFGTLPTTKAPRKEQ", "length": 237, "molWeight": 27422, "crc64": "9EF58769FEBCA5C7", "md5": "DED9CFEA2690386D97206F11D2B1DAD9"}}
{"primaryAccession": "O49606", "text": "This is Actin-depolymerizing factor 9 protein, from Mouse-ear cress, contains 141 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O49606", "organism_name": "Mouse-ear cress", "protein_name": "Actin-depolymerizing factor 9", "length": 141, "firstPublicDate": "2007-02-20", "FUNCTION": "Does not display typical F-actin depolymerizing activity, Exhibits a high ability to stabilize and cross-link actin filaments, Functions as an actin bundling protein with the highest efficiency under acidic conditions (PubMed:21570971), May play a role in the modulation of levels of histone H3 lysine 4 trimethylation and H3 lysine 9 and 14 acetylation at the FLC locus (PubMed:18830798)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the actin-binding proteins ADF family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALKTATSGMWMTDDCKKSFMEMKWKKVHRYVVYKLEEKSRKVTVDKVGAAGESYDDLAASLPEDDCRYAVFDFDYVTVDNCRMSKIFFITWSPEASRIREKMMYATSKSGLRRVLDGVHYELQATDPTEMGFDKIQDRAK", "length": 141, "molWeight": 16370, "crc64": "DECC3116C8318979", "md5": "F709A5110439BF831DB68E4BCE367BAB"}}
{"primaryAccession": "O54769", "text": "This is Fibroblast growth factor 16 protein, from Rat, contains 207 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O54769", "organism_name": "Rat", "protein_name": "Fibroblast growth factor 16", "length": 207, "firstPublicDate": "1999-07-15", "FUNCTION": "Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the heparin-binding growth factors family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAEVGGVFASLDWDLQGFSSSLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELFGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPSKLPSMSRDLFRYR", "length": 207, "molWeight": 23753, "crc64": "1C7A11C8BA3164BC", "md5": "1A2C82EDD853DAA041E277DC88D997EA"}}
{"primaryAccession": "O54858", "text": "This is Carboxypeptidase Z protein, from Rat, contains 652 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O54858", "organism_name": "Rat", "protein_name": "Carboxypeptidase Z", "length": 652, "firstPublicDate": "2006-10-17", "FUNCTION": "Cleaves substrates with C-terminal arginine residues, Probably modulates the Wnt signaling pathway, by cleaving some undefined protein, May play a role in cleavage during prohormone processing (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPTTPLLLAALAALAALAVAAYPSCSPGPDPSGKCQRLASTHSATCVDLHLRTCADAAYNHTSFPTPLEHRSWEAVEASPEYTLLGVLHFLLEGQCNPDLRLLGCSVLAPRCQGGHTQRPCRRVCEGLREACQPAFDAIDMAWPYFLDCTQYFAPEEEGCYDPLEQLRGELDVEEALPSGLPPTFIRFAHHSYAQMVRVLKRTAARCSQVAKTYSIGRSFEGKDLVVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREILIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLASTRGVRTDHIPISQYYWWGKVAPETKAIMKWIQTIPFVLSASLHGGDLVVSYPFDFSKHPHEEKMFSPTPDEKMFKLLARAYADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYGLWQHNKEPLLNFLEMVHRGIKGVVTDKYGKPVKNARILVKGIRHDVTTAPDGDYWRLLPPGSHIVIAQAPGYSKVMKRVTIPLRMKRAGRVDFILQPLGTGPKNFLPGPSRALPRSLDPQGAPAQLDFEPPRARRQPASGSKPWWWAYFTSLSPHKPRWLLKY", "length": 652, "molWeight": 73082, "crc64": "BE085394B91A978C", "md5": "C22C777FEEEAAF928BB0C91FEF32E605"}}
{"primaryAccession": "O59697", "text": "This is Serine/threonine-protein kinase ppk25 protein, from Fission yeast, contains 423 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59697", "organism_name": "Fission yeast", "protein_name": "Serine/threonine-protein kinase ppk25", "length": 423, "firstPublicDate": "2006-10-31", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKPNTTNLRNECWDTFSIPKRSQNIKINQSTKHQRSISDFVGTAGPGRQVGNWIIKKTIGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTVRVQREALLGRLLRHPNICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYLHKNFIVHRDLKIENVLLTQDSRQVKLIDFGLSNFYSKDDLLRTYCGSLYFAAPELLDAKPYIGPEVDVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPSYISEDCCSLIAAMLNVNPRKRCSLEQAAKFPWLKKNSFCLYLPIPLTSIPSTPSIRSHVFKPPFNLKVLQLLHEHGLASIPELKHELYMAYIERKTTSLVCLYLLGVESLAPALRIPTALPPVYSRHQRHHSEILGAMDLTEKITAMQCPP", "length": 423, "molWeight": 47674, "crc64": "FDDDB5BF32A78E80", "md5": "97FE17DECF8358847E88D8C26B38BA0A"}}
{"primaryAccession": "O59800", "text": "This is Pre-mRNA-splicing factor cwf5 protein, from Fission yeast, contains 354 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59800", "organism_name": "Fission yeast", "protein_name": "Pre-mRNA-splicing factor cwf5", "length": 354, "firstPublicDate": "2001-08-29", "FUNCTION": "Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, Binds to RNA (By similarity), Involved in pre-mRNA splicing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RRM SLT11 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSHGPKGDINKQEWEDVEFPSICERCLGDNSYVRMTKEPLGQECKICSKPCTIFRWIKERGQKPGKTQICVGCARYKNCCQSCMLDLQFGLPIALRDAALKLVESGPTNDINREFFAQNQQRLLSNGETAYDSQEASAAARNLVKKVEKRELHSRPPKRKLDDVESKQILKEARASDASLNAERPLFPVKKIINGNVSLSINMEPPKDKKIASLFLIGVEDELADYKIRKHFEQYGPLKSVVCSHRAKCAFVNFKTRSSAEIAAAASPDGNVVIEGFRLKVQWGKPRSLGGPEGEVRNAKLADLVMRGSSHGNKTSQKSTIKNIENEDHENTKSPAVAIPIDPNQPRYRSQIPR", "length": 354, "molWeight": 39576, "crc64": "5283C11C4BD504AA", "md5": "4F8672B3EB3824B5529D35D1386FE356"}}
{"primaryAccession": "O64654", "text": "This is Thioredoxin-like 1-1, chloroplastic protein, from Mouse-ear cress, contains 275 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O64654", "organism_name": "Mouse-ear cress", "protein_name": "Thioredoxin-like 1-1, chloroplastic", "length": 275, "firstPublicDate": "2004-08-31", "FUNCTION": "Thiol-disulfide oxidoreductase that may participate in various redox reactions, Possesses insulin disulfide bonds reducing activity", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the thioredoxin family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTEVISKTSLFLGACGNHHRVDDFSFSPVSFGGFGLKKSFSCLKLKSQKPLRSVFYGKQIVFGDSQDESFRRSSAITAQTTLRIGTAQKWWEKGLKDNMREISSAQELVDSLTNAGDKLVVVDFFSPGCGGCKALHPKICQFAEMNPDVQFLQVNYEEHKSMCYSLGVHVLPFFRFYRGSQGRVCSFSCTNATIKKFRDALAKHGPDRCSLGPTKGLEEKELVALAANKELNFTYTPKPVPVEKEAATPDSNPSLPVPLPSMSSNDEKTLVSAGR", "length": 275, "molWeight": 30323, "crc64": "9FDF02EA341DC4A1", "md5": "8466A525F4F5AE341276EEDE523E19D5"}}
{"primaryAccession": "O74443", "text": "This is SWIRM domain-containing protein laf2 protein, from Fission yeast, contains 272 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74443", "organism_name": "Fission yeast", "protein_name": "SWIRM domain-containing protein laf2", "length": 272, "firstPublicDate": "2007-09-11", "FUNCTION": "Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQILKDQENLNPDGGSFVLITPPLSPPKQKSLSYTNISRRHGMRACMKGIVYEVYKNQPKLWLQQELIWLRRKRIHPIPKARRNNHVGRWANRHSNVSSSSGSRGRSSVSSRDSSPSYSGALRSAERSISSSPSTIEARRRKSARGNGLNGAIDVANLPFEELPNFCPDMSVLDNRTHPRTLKAEWKGPPLDLSDDPYRDLLHPAELHLASTLRLPCLIYLDNKKRIFAEWHHRRQQGLTFRKTDAQRASRVDVNKASRLWKAFHEVGFFDD", "length": 272, "molWeight": 31109, "crc64": "A4518C9DDD3E3184", "md5": "6E8D69FE25980E136FB99AE9B7BBD7EB"}}
{"primaryAccession": "O74462", "text": "This is Transcription initiation factor TFIID subunit 6 protein, from Fission yeast, contains 452 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74462", "organism_name": "Fission yeast", "protein_name": "Transcription initiation factor TFIID subunit 6", "length": 452, "firstPublicDate": "2009-01-20", "FUNCTION": "TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TAF6 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSLTVWNIESIKDVAEMLGIGNLADEPAAAIAMDLEYRIHQVVQEATKFMVHSKRTVLTSADISSALRTLNVEPLYGFNNSRPLEFHEAAVGAGQNSLYYLDDEEVDFEKIINAPLPKVPRNISYSAHWLAIEGVQPAIPQNPTPSDHTVGEWASKGTSGVMPGASTAAKEARNGVTSMDNVEIKPLVRHVLSKELQLYFERITSALLDETNVELRDAALSSLRDDPGLHQLLPYFIMFLSDSVTRNLGNLVVLTTLMHMAWALLDNPNLFVEPYVQQLMPSILTCLVAKRLGSDPNNHEHYALRDLAAFLLGIVCDRFGNVYYTLKPRVTRTALKAFLDNTKPYSTHYGAIKGLKTMGKEAIRVLVVPNIKVYEVLVRKTLEKGNEEEIYEANKCMDALYDALLLLRDDQLPNQRTLPPNASGLLEKNVGSLMAEKIMKENDTSLLLGLLE", "length": 452, "molWeight": 50273, "crc64": "CA3AF8DB81E7AC6D", "md5": "759D7836A803EEF439085222F0D17E01"}}
{"primaryAccession": "O74509", "text": "This is Vacuolar morphogenesis protein 7 homolog protein, from Fission yeast, contains 341 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74509", "organism_name": "Fission yeast", "protein_name": "Vacuolar morphogenesis protein 7 homolog", "length": 341, "firstPublicDate": "2008-06-10", "FUNCTION": "Essential for proper morphogenesis of the vacuole, May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure (By similarity)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALKIKIPETSQSSDEYSRWTVYHIEVAFPNGGKHVVFRRFNEFVALDAQIRPNDYNSRLCKLPSKSWVSSTVTNEKLRESRRLALQAYVQCLSETPWIKMPVVKKFLNIKDESEDETQGQFLGPTDWIQVFQDCKRNLHMYRVDLMSGKSITIGVQTKNVYAIKSLMDNLSESLDKLELANALGPGEILRRKDMLEQLGSEFLSFKRLVKNANSPVAPPSASSQLNSSNPSSPFRPLSASTDKQSNTSLNRVLGKNRMPETQTTKKLDNVGLYNMQNQTMEDQDMQAESLLPIIQRQKELSKMINQEVVEQNSMLDELSNEAYANQKKLHRTRAGLRKLG", "length": 341, "molWeight": 38848, "crc64": "9BB2A35FE2C67FB4", "md5": "58DA9B44A9B2F4AEEC15ABB4B03E6ACA"}}
{"primaryAccession": "O74761", "text": "This is DNA primase large subunit protein, from Fission yeast, contains 459 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74761", "organism_name": "Fission yeast", "protein_name": "DNA primase large subunit", "length": 459, "firstPublicDate": "2003-08-29", "FUNCTION": "Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex - primosome/replisome) which play an essential role in the initiation of DNA synthesis (By similarity), During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit pol1, an accessory subunit spb70/pol12 and two primase subunits, the catalytic subunit spp1/pri1 and the regulatory subunit spp2/pri2) is recruited to DNA at the replicative forks (By similarity), The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the eukaryotic-type primase large subunit family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFRTTKSRVVEKNQNFSSASFESLSYPTRLNFYKKPPVSEISIEEFETWAIDRLVVLGEIESAMLRNKTKNELNGIIKKILDKRLPMSSNMARTVKGNSLDEERRKDHYSHFILRLAFSRSDELRIRFLRAESTLFRFRFVNEETRERQAFIDSLDFQWESVSQEEKDVFYEKLQASSQRNIENESFFKVPFFKVPDLVERRAVFVHKGYAYVPFSEQVSLVVEEFEENLKKALESTAKSLPRLDEDDRLLPILNHLSKGFVAPESSIVAPKSGAITAGQVDSFVSHFPLCAKHLHEVLKRDKHLRHFGRLQYGLFLKDIGLSVDEALVFWRKSFTNVTEDKFNKEYRYNIRHTYGLEGNRKNYKGYNCQQILTGPQLGPGDAHGCPYRTYSVNNLVSALASMGIAPDSAGCREVVEAVKARHYHIACTRVFELTHPNVGSLEESIHHPLQYFQLSLES", "length": 459, "molWeight": 53053, "crc64": "811172102DDFC42E", "md5": "5AD74C1EDB3AAA1A7577FA27E3EA9C82"}}
{"primaryAccession": "O74890", "text": "This is Tyrosine--tRNA ligase, mitochondrial protein, from Fission yeast, contains 445 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74890", "organism_name": "Fission yeast", "protein_name": "Tyrosine--tRNA ligase, mitochondrial", "length": 445, "firstPublicDate": "2008-01-15", "FUNCTION": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the class-I aminoacyl-tRNA synthetase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSRLLACLKQLQARSLIHNTTLLQPSCNVNSVYLGADPTAASLHVGNLVALMPLVHFFLNGFPVFTVIGDATAQLGDPSGRSTSRKQMAETTRTANSNSIHNQLKDLSSSILSYAQDCNYPFSQMPSSSQWSIVRNSSWYENLKLLKFLSSVGPHVRVSQMLARDSVTTRLQSPSGLSFAELTYQLLQAYDYSYLYENHSVNLQIGGSDQWGNITAGTDLVRRTHPNANVYALTTPLLTSSSGQKLGKSAGNAIWLDPKLTDSYSLYQYFISAPDDLACKCLDMLTLLPLEQLEQIKAEHEKDPSQRIVHKYLASNVVRMVHGKKALELAQIQTKLLHGAHQAPFGFYSEAPQQGDSFPSLPEIRALFKDCKFYRTIDSSIKDQPFSRLLRTLQIYTSRKEATEHILSGAVSLGHKPILDSNYKFPDNSLFVLRAGKRTFVLDSL", "length": 445, "molWeight": 49498, "crc64": "E47BD594369C7EE2", "md5": "F29ACC6BACADA03231E6481CBADD9FA9"}}
{"primaryAccession": "O74964", "text": "This is Chromatin structure-remodeling complex subunit rsc1 protein, from Fission yeast, contains 803 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74964", "organism_name": "Fission yeast", "protein_name": "Chromatin structure-remodeling complex subunit rsc1", "length": 803, "firstPublicDate": "2005-09-13", "FUNCTION": "Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning, Controls particularly membrane and organelle development genes", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RSC1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSKIRPSADDKKLQRVLYFFLERVRAAKDVSGQLLSPLIDNASVDTASVSPSSNGRPTTLKSIQSKIDEFQYHDFSEFVSDLAYLFINVKALYEGTQTYSFVQALEEFCIQQLRTFQQQGYIPVITWPNTDSPSATTSSPISRNPEYSVSPPNGSKFVKNEDEAYDSDLYVEEEDSDVKGRSMVGRDGRYKSEDLKRRKLQPSSKPLSSLEARAKVIMRQVRRYRDGSGRQLFAPFERLPDPRMFPEYYQAIEQPMALEVIQKKLSKHRYETIEQFVDDFNLMFDNAKSFNDPSSQVYRDADFLKNYLADVLRLEAGKLDSEFFNYETDSRASPQLPKNDIQPAVSIDGTLLNVGDWVLIRNPADSSKPIVSQIYRIWKSDDDINYVTVCWYLRPEQTVHRADAVFYENEVFKTSLYRDHPVSEIVGRCFVMYITRYIRGRPKGIRSTPVFVCESRYNDDTKQFSKIKSWKACMPQEVSGSEYEMILFDRPITLTKVASPLLHLLASKSQGLPSPATTDSNTHMLPSQGSLLPPSSISETKSFSTKASTPLSTDDIATPLSSAPNPPSVMPTYARKTSSHSERSSHSSYHNSSHVPTAAFNSPIMRTSTKSTSPIPARPFYAQSGSLQSLNTTQHSHQISGGHSGRMNVPYAKLSYTSHNGRHGGSNGNISGAKTPMTNYTINSMPSLPVFPPAFIVPGTHQKLDESSPVPGIDDVTVINTETAKMLDKDEHQNVLWYTVPPLDPIPLENRNGSLTHSVEYVLYKKSKGSQVITEKARSNELSREAKFENLVASLSDALIPP", "length": 803, "molWeight": 90132, "crc64": "2C2706CB022510F7", "md5": "60B59FA293AB0E1E75F7D85962551BE5"}}
{"primaryAccession": "O75363", "text": "This is Breast carcinoma-amplified sequence 1 protein, from Human, contains 584 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O75363", "organism_name": "Human", "protein_name": "Breast carcinoma-amplified sequence 1", "length": 584, "firstPublicDate": "2001-01-24", "FUNCTION": "Required for myelination", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGNQMSVPQRVEDQENEPEAETYQDNASALNGVPVVVSTHTVQHLEEVDLGISVKTDNVATSSPETTEISAVADANGKNLGKEAKPEAPAAKSRFFLMLSRPVPGRTGDQAADSSLGSVKLDVSSNKAPANKDPSESWTLPVAAGPGQDTDKTPGHAPAQDKVLSAARDPTLLPPETGGAGGEAPSKPKDSSFFDKFFKLDKGQEKVPGDSQQEAKRAEHQDKVDEVPGLSGQSDDVPAGKDIVDGKEKEGQELGTADCSVPGDPEGLETAKDDSQAAAIAENNNSIMSFFKTLVSPNKAETKKDPEDTGAEKSPTTSADLKSDKANFTSQETQGAGKNSKGCNPSGHTQSVTTPEPAKEGTKEKSGPTSLPLGKLFWKKSVKEDSVPTGAEENVVCESPVEIIKSKEVESALQTVDLNEGDAAPEPTEAKLKREESKPRTSLMAFLRQMSVKGDGGITHSEEINGKDSSCQTSDSTEKTITPPEPEPTGAPQKGKEGSSKDKKSAAEMNKQKSNKQEAKEPAQCTEQATVDTNSLQNGDKLQKRPEKRQQSLGGFFKGLGPKRMLDAQVQTDPVSIGPVGKSK", "length": 584, "molWeight": 61709, "crc64": "22921C0B37129944", "md5": "96DE4C093B453B77D6C2B1D905210697"}}
{"primaryAccession": "O80678", "text": "This is UBP1-associated protein 2B protein, from Mouse-ear cress, contains 451 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O80678", "organism_name": "Mouse-ear cress", "protein_name": "UBP1-associated protein 2B", "length": 451, "firstPublicDate": "2014-02-19", "FUNCTION": "Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as component of a complex regulating the turnover of mRNAs in the nucleus, Binds with high affinity to RNA molecules that contain U-rich sequences in 3'-UTRs, May function in complex with UBP1 and contribute to the stabilization of mRNAs in the nucleus (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTKKRKLESESNETSEPTEKQQQQCEKEDPEIRNVDNQRDDDEQVVEQDTLKEMHEEEAKGEDNIEAETSSGSGNQGNEDDDEEEPIEDLLEPFSKDQLLILLKEAAERHRDVANRIRIVADEDLVHRKIFVHGLGWDTKADSLIDAFKQYGEIEDCKCVVDKVSGQSKGYGFILFKSRSGARNALKQPQKKIGTRMTACQLASIGPVQGNPVVAPAQHFNPENVQRKIYVSNVSADIDPQKLLEFFSRFGEIEEGPLGLDKATGRPKGFALFVYRSLESAKKALEEPHKTFEGHVLHCHKANDGPKQVKQHQHNHNSHNQNSRYQRNDNNGYGAPGGHGHFIAGNNQAVQAFNPAIGQALTALLASQGAGLGLNQAFGQALLGTLGTASPGAVGGMPSGYGTQANISPGVYPGYGAQAGYQGGYQTQQPGQGGAGRGQHGAGYGGPYMGR", "length": 451, "molWeight": 49026, "crc64": "4C6BE8A2A952D17D", "md5": "787C1EE1E4ED95AF7054153FD73E286E"}}
{"primaryAccession": "O80839", "text": "This is LIM domain-containing protein PLIM2a protein, from Mouse-ear cress, contains 226 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O80839", "organism_name": "Mouse-ear cress", "protein_name": "LIM domain-containing protein PLIM2a", "length": 226, "firstPublicDate": "2014-10-29", "FUNCTION": "Binds to actin filaments and promotes cross-linking into thick bundles, Has an actin-stabilizing activity, The actin regulatory activities are inhibited by pH > 6,8 but are [Ca(2+)] independent", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSFTGTLDKCKACDKTVYVMDLLTLEGNTYHKSCFRCTHCKGTLVISNYSSMDGVLYCKPHFEQLFKESGNYSKNFQAGKTEKPNDHLTRTPSKLSSFFSGTQDKCATCKKTVYPLEKVTMEGESYHKTCFRCTHSGCPLTHSSYASLNGVLYCKVHFNQLFLEKGSYNHVHQAAANHRRSASSGGASPPSDDHKPDDTASIPEAKEDDAAPEAAGEEEPEPVVES", "length": 226, "molWeight": 24943, "crc64": "A1017098C3E58E42", "md5": "576E5C6B6B02BCC892AD16CA35ED4333"}}
{"primaryAccession": "O81027", "text": "This is Hydroxymethylglutaryl-CoA lyase, mitochondrial protein, from Mouse-ear cress, contains 468 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O81027", "organism_name": "Mouse-ear cress", "protein_name": "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "length": 468, "firstPublicDate": "2009-12-15", "FUNCTION": "Involved in the catabolism of branched amino acids such as leucine", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the HMG-CoA lyase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQWNGVRRAHSIWCKRLTNNTHLHHPSIPVSHFFTMSSLEEPLSFDKLPSMSTMDRIQRFSSGACRPRDDVGMGHRWIEGRDCTTSNSCIDDDKSFAKESFPWRRHTRKLSEGEHMFRNISFAGRTSTVSGTLRESKSFKEQKYSTFSNENGTSHISNKISKGIPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIQRLVSSGLPVVEATSFVSPKWVPQLADAKDVMDAVNTLDGARLPVLTPNLKGFQAAVSAGAKEVAIFASASESFSLSNINCTIEESLLRYRVVATAAKEHSVPVRGYVSCVVGCPVEGPVLPSKVAYVVKELYDMGCFEISLGDTIGIGTPGSVVPMLEAVMAVVPADKLAVHFHDTYGQALANILVSLQMGISIVDSSIAGLGGCPYAKGASGNVATEDVVYMLNGLGVHTNVDLGKLIAAGDFISKHLGRPNGSKAAVALNRRITADASKI", "length": 468, "molWeight": 50577, "crc64": "C91C70DAD241AF74", "md5": "84A6F3BC36614CA85ADF10F96C072AE7"}}
{"primaryAccession": "O81796", "text": "This is Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial protein, from Mouse-ear cress, contains 368 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O81796", "organism_name": "Mouse-ear cress", "protein_name": "Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial", "length": 368, "firstPublicDate": "2007-01-09", "FUNCTION": "Performs an essential role in the oxidative function of the citric acid cycle", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MARRSVSIFNRLLANPPSPFTSLSRSITYMPRPGDGAPRTVTLIPGDGIGPLVTGAVEQVMEAMHAPVHFERYEVLGNMRKVPEEVIESVKRNKVCLKGGLATPVGGGVSSLNMQLRKELDIFASLVNCINVPGLVTRHENVDIVVIRENTEGEYSGLEHEVVPGVVESLKVITKFCSERIARYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCREVAKHYSGITYNEIIVDNCCMQLVAKPEQFDVMVTPNLYGNLIANTAAGIAGGTGVMPGGNVGAEHAIFEQGASAGNVGNDKMVEQKKANPVALLLSSAMMLRHLRFPTFADRLETAVKQVIKEGKYRTKDLGGDCTTQEVVDAVIAALE", "length": 368, "molWeight": 39957, "crc64": "28EDD697B921650D", "md5": "F32C3622E8E5B8C0C1B7CFE13DDA9EFA"}}
{"primaryAccession": "O82291", "text": "This is Probable plastid-lipid-associated protein 3, chloroplastic protein, from Mouse-ear cress, contains 376 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O82291", "organism_name": "Mouse-ear cress", "protein_name": "Probable plastid-lipid-associated protein 3, chloroplastic", "length": 376, "firstPublicDate": "2005-04-26", "FUNCTION": "Probably involved in light/cold stress-related jasmonate (JA) biosynthesis", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the PAP/fibrillin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATLFTVARPSSLLYVSSINPSKTFSPSISLKLNSLSFSFGYRPKPLRFSKIRSSLPSESESESDLDASAVTDEWGEKPGDANEPDSQPDNVTVNVITDEWGEKSGPELEESGTRFMESDPPRNEDEWGGEIGGETEADAGNGSAVSDPTWELKRCLADSVYGTELGFKAGSEVRAEVLELVNQLEALNPTPAPLENPELLDGNWVLLYTAFSELIPLLAAGSTPLLKVKSISQSIDTNNLIIDNSTTLSSPFADFSFSATASFEVRSPSRIEVSFKEGTLKPPVIKSSVDLPESVGVFGQQISLSLLKQSLNPLQDVAANISRALSGQPPLKLPFPGNRGSSWLLTTYLDKDLRISRGDGGLFVLAREGSSLLEL", "length": 376, "molWeight": 40505, "crc64": "DA958852D317F555", "md5": "6FF28BAFD24B85E5CC9162239C70D780"}}
{"primaryAccession": "O82359", "text": "This is Sphingoid long-chain bases kinase 2, mitochondrial protein, from Mouse-ear cress, contains 364 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O82359", "organism_name": "Mouse-ear cress", "protein_name": "Sphingoid long-chain bases kinase 2, mitochondrial", "length": 364, "firstPublicDate": "2013-05-01", "FUNCTION": "Involved in the production of sphingoid long-chain base (LCB), Is required for the cold-induced accumulation of phytosphingosine-phosphate, the regulation of the cold-responsive MPK6 and reduction of root growth at moderate low temperature", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRSTCCTPLCPFTAKQPSFLRKQQRITSDRFTFRGGGGGDAAAVVSSSGLRDLVFVVNPQGANGRTAKEWKKLLPHLRSRLGKDCNVSELLTSGPSHAIDITREAIRDGADAVIAVGGDGTLHEVVNGFFWEGKPVGYLSGEASRSTALGLIPLGTGSDFARTFGWNNDPCEAVERIARGMRSRIDVGVIDKEGKDLHYFINVADVHLSAKAGFYASKYKKFGNLCYVIGALQAFMGHHNQDMRIRVNGGEWEIYPQVTALCVGNAKYFGGGMKITPNAIPGNGNLEVVVLQNFKWYDFVLKLHKLYNGTHLSVNNVTSRSVQSIEVEEITDSGSIYVQSDGEHLGFLPRKFQVLPGAIDIIS", "length": 364, "molWeight": 39655, "crc64": "93B755F11A948F0E", "md5": "3CFD14029011F5BE4E255CC563451AB4"}}
{"primaryAccession": "O94251", "text": "This is Ribonucleases P/MRP protein subunit POP7 protein, from Fission yeast, contains 102 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94251", "organism_name": "Fission yeast", "protein_name": "Ribonucleases P/MRP protein subunit POP7", "length": 102, "firstPublicDate": "2007-09-11", "FUNCTION": "Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, Also a component of RNase MRP, which cleaves pre-rRNA sequences (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone-like Alba family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVERIKRAPAFRKGIIIRRKTHLIAMIRRMRKKLDIDGSILYQATGMAIPHLVELSDKYKRQGYNISMDTATVEFMDEIVDEVSIQNKNRLGNVLLLRVSR", "length": 102, "molWeight": 11843, "crc64": "4755FA5DB10B3B4A", "md5": "745CA19FDF0AFADE4C55FA1C54AAA9FB"}}
{"primaryAccession": "O94275", "text": "This is Probable E3 ubiquitin-protein ligase mug30 protein, from Fission yeast, contains 807 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94275", "organism_name": "Fission yeast", "protein_name": "Probable E3 ubiquitin-protein ligase mug30", "length": 807, "firstPublicDate": "2007-09-11", "FUNCTION": "Probable E3 ubiquitin-protein ligase, Has a role in meiosis", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSRPIEIANVSSGNRRTLPALHGSSFSSRSELDNNTNSKISRRLRELVCQRMGENPLRLRQSFHETISNDSYGNSEKLVIRPCICCNSVLRYPAQAMCFRCSLCMTVNDVYFCLSGSQIKTKASTDGSQFISVEHFVETIHQTRSALQLAKQRTGNVQAIVAAGLPLRELISLVFGSPPILNKLFSVKNGCSIQSSGLNYKLIYQLYHDITNLDILITNELLRAIESLLRRPMLYCHDPADYQYLLILLENPLLNSKSKNIVNKSSSILKRILGVLSNLNEKTHHFFISCFKKQPYNNPKFFRRKVDLINKFIGQRLMETYSRNKRKHYYNNDWQIKSAAITMALLYSANSQMRLIDRSSFYCIMADFINLYHDFELWEQKINCFCFCQYPFLLSMGAKISILQLDARRKMEIKAREAFFSSILSKMNVEPYLMIRVRRDRLLEDSLRQINDRNKDFRKALKVEFLGEEGIDAGGLKREWLLLLTRKVFSPEFGLFVNCEESSNYLWFNYSHRSKEIDYYHMSGILMGIAIHNSINLDVQMPRAFYKKLLQLPLSFNDLDDFQPSLYRGLKELLLFEGDVKNTYGLNFTINLKAVEGFRTVELKEGGSELSVDNENRKEYVLRYVDYLLNTTVKKQFSAFFDGFMKVCGGNAISLFQDNEISKLIRGSEEVIDWELLKNVCVYDFYDQNAISNSISESEPSMTASKYLCHSFVSKRKIILWFWDLISHYSLKMQKLFLIFVTGSDRIPATGAHNFQLRISVLGPDSDQLPISHTCFNHLCIWEYSSREKLKKKLDTALLETNGFNIR", "length": 807, "molWeight": 93415, "crc64": "7203EB2667E2D3AB", "md5": "2AC30BD2A47397618563074F7E08542B"}}
{"primaryAccession": "O94639", "text": "This is Zinc-regulated transporter 1 protein, from Fission yeast, contains 408 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94639", "organism_name": "Fission yeast", "protein_name": "Zinc-regulated transporter 1", "length": 408, "firstPublicDate": "2008-02-05", "FUNCTION": "High-affinity zinc transport protein, Regulates intracellular zinc levels", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the ZIP transporter (TC 2,A,5) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSLNNLSNSYNQYLAQESHQILRHLFLNKQYSPLVKRDDDSSATVTCGGDANEFNEYGHLGYRIGAIFVILATSLIGMNLPLVLSKITKNRPNVYIEYLYLFARYFGSGVILATAFIHLLAPACNKLYDPCLDDLFGGYDWAPGICLISCWFILLLEVLLNRYVEWRFGMEIGDHHGPTLGAKQHSHSHEDGAHGVHEHPVYDIEECADGVEHECVKDDLEEVKLEPYTNTDSTDLTTKEEARSFLLKQQLTAFIILESSIILHSVIIGLTTAVSGEEFKTLFPVIIFHQAFEGCGLGSRLAGMAWGPKTAWVPWVLGVIYSLVTPIGMAAGLGVREHWDPLAHGSYAAQGVLDAISSGILVYAGLVELLAHDFLFSPERERNWYKLIYLLACSMAGTGVMALLGKWA", "length": 408, "molWeight": 45272, "crc64": "0EBC0AF53CC3F0CE", "md5": "AB2BD2316B2712B2012693FCB8E05029"}}
{"primaryAccession": "O94682", "text": "This is CENP-A recruiting complex protein mis20 protein, from Fission yeast, contains 253 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94682", "organism_name": "Fission yeast", "protein_name": "CENP-A recruiting complex protein mis20", "length": 253, "firstPublicDate": "2007-09-11", "FUNCTION": "Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A (PubMed:24774534, PubMed:24789708), Seems dispensable for proper chromosome segregation (PubMed:24774534)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLEQSESHAFINNAPKEDRIQVKFEQLFESLPLPLRAEEALSKLRHDSARLMILKTSDPTLNMSTYSIEDSPMGFECLKYNLSDNNKLLSQNNYRLPDYLEEDEIVSYTFSKTGPTTSKNKHPSHSNTIRSPPYKVKKESCHTEINNVSNVSTESINVIDASRGYSPYTSVDSLSVSKNRSFISLEESASNQYDAAEAFYFNADSSSPLRKLSPIELPVTPIRRKTPTINPNSELKRLQTFGKLILHKGSRRR", "length": 253, "molWeight": 28725, "crc64": "A979AA30FADDBC8A", "md5": "D27068184D52687A77BDDC838218EA4C"}}
{"primaryAccession": "O94752", "text": "This is Enhancer of mRNA-decapping protein 3 protein, from Fission yeast, contains 454 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94752", "organism_name": "Fission yeast", "protein_name": "Enhancer of mRNA-decapping protein 3", "length": 454, "firstPublicDate": "2005-11-22", "FUNCTION": "Stimulates decapping of both stable and unstable mRNA during mRNA decay, Stimulates decapping presumably by preventing the DCP1-DCP2 decapping complex from adopting an inactive conformation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the EDC3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSVADFYGSNVEVLLNNDSKARGVITNFDSSNSILQLRLANDSTKSIVTKDIKDLRILPKNEIMPKNGTKSPSTNSTKLKSAETYSSKNKWSMDCDEEFDFAANLEKFDKKQVFAEFREKDKKDPAKLLVSHNKSPNRNYHHKQNVLGPSVKDEFVDLPSAGSQINGIDAVLSSSSNGHVTPGSKKGSRETLKKKPFVDENIPAELHTTTGDILKPITPEQLSQGIALAIAKTSTDIVVENAAQLLSQFVFSVLGGHKRLSSRNHNSQPLVCILVGSHDHASAAVAAGRRLCAIGIKVVLRLLTPFNVDNRQLLMFQAAGGYIPTENFDQFLNKLTSPIELVVDVLTGFHPSIDKNSHALIQWANDLNVLILSVDIPSGYTVQKKNTAILPKWTLALGAVTTTLAQAALVKQAAGVSVFVGNLGTGSQTWAELGILESQVTGQYLAQISCTSTN", "length": 454, "molWeight": 49219, "crc64": "F488C398D2550275", "md5": "90909491E004A672A0627685372B09B5"}}
{"primaryAccession": "O95841", "text": "This is Angiopoietin-related protein 1 protein, from Human, contains 491 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O95841", "organism_name": "Human", "protein_name": "Angiopoietin-related protein 1", "length": 491, "firstPublicDate": "2005-05-10", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKTFTWTLGVLFFLLVDTGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID", "length": 491, "molWeight": 56720, "crc64": "3C4DB8DEF6CF7E99", "md5": "E7D565506EF08A408A21ECA3C0A7310E"}}
{"primaryAccession": "P01142", "text": "This is Corticoliberin protein, from Sheep, contains 190 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P01142", "organism_name": "Sheep", "protein_name": "Corticoliberin", "length": 190, "firstPublicDate": "1986-07-21", "FUNCTION": "Hormone regulating the release of corticotropin from pituitary gland (PubMed:6267699, PubMed:6273874), Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRLPLLVSVGVLLVALLPSPPCRALLSRGPIPGARQASQHPQPLSFFQPLPQPQEPQALPTLLRVGEEYFLRLGNLDETRAAPLSPAASPLASRSSSRLSPDKVAANFFRALLQPRRPLDSPAGPAKRGTENALGSRQEAPAARKRRSQEPPISLDLTFHLLREVLEMTKADQLAQQAHSNRKLLDIAGK", "length": 190, "molWeight": 20672, "crc64": "E9599B97E85186FE", "md5": "84E06FEDB9F63475EF676A4F2B95633C"}}
{"primaryAccession": "P03872", "text": "This is Partitioning protein REP2 protein, from Baker's yeast, contains 296 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P03872", "organism_name": "Baker's yeast", "protein_name": "Partitioning protein REP2", "length": 296, "firstPublicDate": "1986-07-21", "FUNCTION": "Part of the plasmid partitioning system, which ensures the equal distribution of replicated plasmid molecules to daughter cells, The plasmids exist as well-organized plasmid foci within the nucleus that stay together throughout the cell-cycle and act as entity during segregation, effetively reducing copy number to one, Plasmid partitioning requires the proteins REP1, REP2, and a cis-acting locus STB (REP3), REP1-REP2 stably associate with CSE4-containing chromatin at STB during S-phase, marking the locus with a centromeric tag, and thereby probably catching mitotic spindle microtubules to the plasmid cluster and coupling plasmid segregation to chromosome segregation, REP1-REP2 are required to recruit the cohesin complex to the STB locus for pairing of the replicated plasmid cluster, a prerequisite for successful plasmid segregation, REP1-REP2 also negatively regulate expression of site-specific recombinase FLP and of RAF1", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDDIETAKNLTVKARTAYSVWDVCRLFIEMIAPDVDIDIESKRKSDELLFPGYVIRPMESLTTGRPYGLDSSAEDSSVSSDSSAEVILPAAKMVKERFDSIGNGMLSSQEASQAAIDLMLQNNKLLDNRKQLYKSIAIIIGRLPEKDKKRATEMLMRKMDCTQLLVPPAPTEEDVMKLVSVVTQLLTLVPPDRQAALIGDLFIPESLKDIFNSFNELAAENRLQQKKSELEGRTEVNHANTNEEVPSRRTRSRDTNARGAYKLQNTITEGPKAVPTKKRRVATRVRGRKSRNTSRV", "length": 296, "molWeight": 33196, "crc64": "FF54CBC6B90F5FAF", "md5": "8B2E3B23CE3F5DCC16F0E2C404D8BB61"}}
{"primaryAccession": "P05366", "text": "This is Serum amyloid A-1 protein protein, from Mouse, contains 122 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P05366", "organism_name": "Mouse", "protein_name": "Serum amyloid A-1 protein", "length": 122, "firstPublicDate": "1988-11-01", "FUNCTION": "Major acute phase protein", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the SAA family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLLTSLVFCSLLLGVCHGGFFSFVHEAFQGAGDMWRAYTDMKEANWKNSDKYFHARGNYDAAQRGPGGVWAAEKISDGREAFQEFFGRGHEDTIADQEANRHGRSGKDPNYYRPPGLPDKY", "length": 122, "molWeight": 13770, "crc64": "0AEF6D5F208EA4D0", "md5": "E68C5137C09A3A68EF71BB13C0EBA471"}}
{"primaryAccession": "P05747", "text": "This is Large ribosomal subunit protein eL29 protein, from Baker's yeast, contains 59 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P05747", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein eL29", "length": 59, "firstPublicDate": "1988-11-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eL29 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAKSKNHTAHNQTRKAHRNGIKKPKTYKYPSLKGVDPKFRRNHKHALHGTAKALAAAKK", "length": 59, "molWeight": 6669, "crc64": "ACED5822295F53F7", "md5": "DC17FE58671F6F5CC120C1FDDEB93569"}}
{"primaryAccession": "P07266", "text": "This is Mitochondrial RNA-splicing protein MRS1 protein, from Baker's yeast, contains 363 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P07266", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial RNA-splicing protein MRS1", "length": 363, "firstPublicDate": "1988-04-01", "FUNCTION": "Function in mitochondrial RNA splicing in the excision of mitochondrial group I introns aI5 beta from COX1 and bI3 from COB transcripts and thus would be involved in obtaining the correct structure of the intron, to allow the RNA catalyzed reactions to occur", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSPKNITRSVIPAIDLYCRKANFKTLKSLSMILGSKKEWYDTKKAPLRTFLVSRCGIFEQLRGRLVEDGKVNLFSVFLTNDSFSFCKMTVDDKFNTSLVDWQKIPFDSTFATDRRQNISLLPVDTLFATEKIISILGVSPNMTNLVSIERERSDLVDFNCKLQSNILEHLLYAKCQGVYVTSTNEKARLLAAVCNPEFIDTFWCELTPIRVSLKENPSISVPREYQMYDPVVRATIKEVVTKRLLRSAFDNDIDPLMCLHLDKGWKLKFPILSSTTGLNFSLKDCLSLDTGKDASDMTEVFLATMESSKVLRTYSNLVDIVMKDNGRLDSGVLKQFNDYVKQEKLNLQHFQAGSSKFLKGAKI", "length": 363, "molWeight": 41290, "crc64": "6270FCD7EBF8267E", "md5": "B41D496A4337AAAE2180379EF2898417"}}
{"primaryAccession": "P07665", "text": "This is Serendipity locus protein beta protein, from Fruit fly, contains 356 amino acids, has 1 C2H2-type 1; degenerate Zinc finger, has 5 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [171, 193], "description": "C2H2-type 1; degenerate", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 1; degenerate Zinc finger"}, {"location": [201, 223], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [229, 251], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [257, 279], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [286, 308], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [315, 337], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "P07665", "organism_name": "Fruit fly", "protein_name": "Serendipity locus protein beta", "length": 356, "firstPublicDate": "1988-04-01", "FUNCTION": "Binds to the consensus DNA sequence 5'-YCAGAGATGCGCA-3'", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type 1; degenerate Zinc finger": 1, "C2H2-type Zinc finger": 5}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSTRPFCFVCGKEKSVGVFQLIEGCIVPGTFKPIKDILKYFEKIINQRLELLPNSAACRDCLEYLFNYDRLVRNLSQVQRQIADALLGCRQVEGKAETKQQAAKRARVQVPAFKIVQATALKEPERQPGEEDECEEFMKEEMLDEEFQFSEPDDSMPSSEEEFFTETTEIPCHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAEAKEATVTFF", "length": 356, "molWeight": 41709, "crc64": "6B5F2206A20CE8D4", "md5": "A4B1A1124031B5E2A0E0518C5C265B1E"}}
{"primaryAccession": "P0C5W7", "text": "This is Brevinin-1DYb protein, from Dybovsky's frog, contains 66 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C5W7", "organism_name": "Dybovsky's frog", "protein_name": "Brevinin-1DYb", "length": 66, "firstPublicDate": "2007-11-13", "FUNCTION": "Antimicrobial peptide, Has low activity against the Gram-positive bacterium S,aureus and the Gram-negative bacterium E,coli (MIC<15 uM), Has a strong hemolytic activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTLKKSLLLLFFLGTISLSLCEEERNAEEERRDYPEERDVEVEKRFLSLALAALPKLFCLIFKKC", "length": 66, "molWeight": 7785, "crc64": "DED229683087C342", "md5": "030A71CA01079EA8FA7D3E6BB562D144"}}
{"primaryAccession": "P0C7L0", "text": "This is WAS/WASL-interacting protein family member 3 protein, from Mouse, contains 485 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C7L0", "organism_name": "Mouse", "protein_name": "WAS/WASL-interacting protein family member 3", "length": 485, "firstPublicDate": "2008-06-10", "FUNCTION": "May be a regulator of cytoskeletal organization (Potential), May have a role in spermatogenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPVPPPPPPPPPPPPPPPPPLGAPPPPPLGAPPPPPPPGPPVSTDTPSLRKPDLKGRSALLADIQQGTRLRKVTQINDRSAPQIEGSKGTSKEGGAAGSNARGGNTPPALGDLFAGGFPVLRPAGQRDVSGGKSGQGPGSRAPSPRLPIKAISGPLPAPASPRLGNASETHSSARPVPPRPSVPAPPPPTPPPPPPPPLPPASPIKAQLVSPPAPPTKVNPSVVPPPLPCAPPLPPPPPTPPPLPPASALSDKAVRPQLAPLHLPPIPPPLPLLPPCGYPGLHSEPNSPAQEVREPPAPPPPPPPPPPPPLPTYASCSSRTAVAPPPLPGANNSGSETPPPLPPKSPSFQTQKALPTPPGAPGPQAILQKKRRGPGTSGGKLNPPPAPPARSPTTELSSKSQQPGGQLRNGGQHAIDDFESKFTFHSMEDFPPPDEYKPCQKIYPSKVPRSRTPGSWLQAEAAGQSSDDIKSRNSQLSLKALPVR", "length": 485, "molWeight": 49453, "crc64": "1ACA37E855D40447", "md5": "5B90AA2616A993B0C078200275604946"}}
{"primaryAccession": "P0CB05", "text": "This is Centrosomal protein of 63 kDa protein, from Chicken, contains 711 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CB05", "organism_name": "Chicken", "protein_name": "Centrosomal protein of 63 kDa", "length": 711, "firstPublicDate": "2009-09-01", "FUNCTION": "Required for normal spindle assembly, Plays a key role in mother-centriole-dependent centriole duplication (PubMed:19182792), Plays a role in DNA damage response (PubMed:19182792), Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (PubMed:19182792)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CEP63 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEALLEGMQRNGQGSSGFLTSCEAELQELMKQIDIMVAHKKAEWEGQTQALEACLGVREQELSSARAALEEKHKEVGKLRQQLEDMEAAKQDLVREYEQQLKKFQEELARLRRSYEKLQKKQLREAREEATKRQGDDQCEMSRLSRKLEEFRQKSLDWEKQRLLYQQQVASLEAQRKALAEQSELIQTQLASRKQILESVELASRSEIQHLTSKLERANDTICANELEVERLNMRVDDLTENNRMILEDQQRVAEELRQSKKMLEVLQDEKMELRATLQSQEDFIDSSKLHQEQLQKELARVTETLHTKEILIRALEERLQEKQLSSPGLEHILLQLDVAQEKEQHLQAEVTHLEDSLVSSNARCVQLSEELAESIKELQSMEEHRAESKVEIKKLKEQLSQAEQIHRGELEGMRKEILRLTQELHQRDITIASAGGSTSDLEQRLRMEIERAERKAVEHRMILVQLETLKLENRHLSEMLEKVELGVLEGKDATLRALSEDYVVELNKLKSENQQLKKDLSEAREKLELTTQSQPEGTAQQLQSEEPEPRDVQHRPTQESQHKQDEQTEKIHHKPDKTTQHHQRWKIQPLPAEIPVAVIPEASVLPTQTSRKSCVESPTLAAGALQGTDSLLLVLDDSKGFPDATSRQSNHEQESVPLCPLPTSSVGSVAARYLEEEELRSQHILECLDAHIEELKKESEKIVRHFGHQE", "length": 711, "molWeight": 82000, "crc64": "C64180F51FE4E174", "md5": "682B41AACD877EC9F4DA800789D34B9F"}}
{"primaryAccession": "P0CT87", "text": "This is 4-O-methyl-glucuronoyl methylesterase 1 protein, from White-rot fungus, contains 472 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CT87", "organism_name": "White-rot fungus", "protein_name": "4-O-methyl-glucuronoyl methylesterase 1", "length": 472, "firstPublicDate": "2016-04-13", "FUNCTION": "Glucuronoyl esterase which may play a significant role in biomass degradation, as it is considered to disconnect hemicellulose from lignin through the hydrolysis of the ester bond between 4-O-methyl-D-glucuronic acid residues of glucuronoxylans and aromatic alcohols of lignin (PubMed:18854978, PubMed:19897892), Can hydrolyze benzyl glucuronic acid (BnGlcA), allyl glucuronic acid (allylGlcA) and to a lower degree methyl glucuronic acid (MeGlcA) in vitro (PubMed:28429057)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the carbohydrate esterase 15 (CE15) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKSAAYLAALAAVLPAYVNAQAQEWGQCGGIGWTGATTCVSGTVCTVLNPYYSQCLPGTATTAPPPPPPPPTSVSSSSSSSTSSAPPSGPSGTSPTCSVASTIPGFSNAALPNPFVFNDGSPVQSKADFTCRQQQILALIQGYEAGALPGPPQSVTASFSKSGSTGTLSITVTDNGKSISFAPTISIPSGTPPANGWPLVIAFEGGSIPIPAGIAKLTYSNSDMAQQTDTSSRGKGLFYNLYGSGATASAMTAWAWGVSRIIDALEKTPSAQINTQRIAVTGCSRDGKGALMAGALEPRIALTIPQESGSGGDTCWRLSKAESDQGHQVQTATEIVTENVWFSTNFNNYVNNLNVLPYDHHMLMALVAPRALVSFENTDYTWLSPMSAWGCVNAAHTVFSALGVADHHGFAQVGGHAHCAWPDSLTPSLNAFFNRFLLDQNVDTNVFTTNNQFGGATWTQSSWINWSTPTLS", "length": 472, "molWeight": 49192, "crc64": "7C3C6263A62B3980", "md5": "F7B617B96AFBC4AB77C4EE1FB905D13F"}}
{"primaryAccession": "P0CT88", "text": "This is 4-O-methyl-glucuronoyl methylesterase 2 protein, from White-rot fungus, contains 407 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CT88", "organism_name": "White-rot fungus", "protein_name": "4-O-methyl-glucuronoyl methylesterase 2", "length": 407, "firstPublicDate": "2016-04-13", "FUNCTION": "Glucuronoyl esterase which may play a significant role in biomass degradation, as it is considered to disconnect hemicellulose from lignin through the hydrolysis of the ester bond between 4-O-methyl-D-glucuronic acid residues of glucuronoxylans and aromatic alcohols of lignin", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the carbohydrate esterase 15 (CE15) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFSWLSFVLLALPVLALARPSEHEARSLFCSTPSNIPFNDDKLPDPFKFNDGSPVRSFADWDCRRQQLSALIQGYEAGTLPPRPPVVTSTFTKSGTTGNLTVTAGFPGKTITFSSPITFPTGTAPFGGWPLVIAYGGVSIPIPDGIAVLTYDNSAMAEQNDQSSRGVGLFFDVYGANATASSMTAWVWGLSRIIDSLEVTPAAHINTAKIAVTGCSRNGKGALMAGAFEERIALTIPQESGSGGDTCWRLSKFEQDSGDVVQQATEIVQENVWFSTNFDNYVFNISLLPYDHHELAALVAPRPLISYENTDFEWLSPLSGFGCMTAAHTVWEAMGIPDKHGFVQVGNHSHCDFPSSLNPTLFAFFDKFLLGKEANTSIFETNGLFNGTEWVASQWINWTTPRFTLL", "length": 407, "molWeight": 44294, "crc64": "6488B4CF722CC1C8", "md5": "44A046A8B43324173651B282D53E03F9"}}
{"primaryAccession": "P0DL36", "text": "This is Mu-scoloptoxin(03)-Ssm2a protein, from Chinese red-headed centipede, contains 112 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0DL36", "organism_name": "Chinese red-headed centipede", "protein_name": "Mu-scoloptoxin(03)-Ssm2a", "length": 112, "firstPublicDate": "2014-02-19", "FUNCTION": "Gating-modifier toxin that inhibits voltage-gated sodium channel with a preference for hNav1,7/SCN9A (IC(50)=25,4 nM) over hNav1,1/SCN1A (IC(50)=4,1 uM), hNav1,2/SCN2A (IC(50)=813 nM), and hNav1,6/SCN8A (IC(50)=15,2 uM) (PubMed:24082113), Is an effective analgesic in rodent pain models, since it is several-fold more effective than morphine in a rodent model of formalin-induced pain and is equipotent with morphine in its ability to reduce thermal and acid-induced pain (PubMed:24082113), In addition, this peptide shows a high level of resistance to proteases and a high thermal stability that may be explained by its predominant composition of alpha-helices (PubMed:24082113)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the scoloptoxin-03 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRIWSLTRILTFIVIFNFAEAGGECMKKCDSPDMIREIFTRCTMVKRDTQFSENSGHLIPKRSVVADNKCENSLRREIACGQCRDKVKTDGYFYECCTSDSTFKKCQDLLHK", "length": 112, "molWeight": 12990, "crc64": "1F1217BB64B6C916", "md5": "614D8CF7B51CD12C237DBA25B9223D66"}}
{"primaryAccession": "P11490", "text": "This is Plastocyanin minor isoform, chloroplastic protein, from Mouse-ear cress, contains 171 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P11490", "organism_name": "Mouse-ear cress", "protein_name": "Plastocyanin minor isoform, chloroplastic", "length": 171, "firstPublicDate": "1989-10-01", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I, Seems to be a minor plastocyanin in Arabidopsis", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAITSATVTIPSFTGLKLAVSSKPKTLSTISRSTSATRAPPKLALKSSLKDFGVIAVATAASIVLAGNAMAMEVLLGSDDGSLAFVPSEFTVAKGEKIVFKNNAGFPHNVVFDEDEIPSGVDASKISMDETALLNGAGETYEVTLTEPGSYGFYCAPHQGAGMVGKLTVK", "length": 171, "molWeight": 17589, "crc64": "F74CD9807ED626B2", "md5": "BAF905754B24EC5671B2E75DA054923F"}}
{"primaryAccession": "P12359", "text": "This is Oxygen-evolving enhancer protein 1, chloroplastic protein, from Spinach, contains 332 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P12359", "organism_name": "Spinach", "protein_name": "Oxygen-evolving enhancer protein 1, chloroplastic", "length": 332, "firstPublicDate": "1989-10-01", "FUNCTION": "Stabilizes the manganese cluster which is the primary site of water splitting (By similarity), Binds GTP after preillumination of photosystem II core complex, This binding is inhibited by DCMU", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the PsbO family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAASLQASTTFLQPTKVASRNTLQLRSTQNVCKAFGVESASSGGRLSLSLQSDLKELANKCVDATKLAGLALATSALIASGANAEGGKRLTYDEIQSKTYLEVKGTGTANQCPTVEGGVDSFAFKPGKYTAKKFCLEPTKFAVKAEGISKNSGPDFQNTKLMTRLTYTLDEIEGPFEVSSDGTVKFEEKDGIDYAAVTVQLPGGERVPFLFTIKQLVASGKPESFSGDFLVPSYRGSSFLDPKGRGGSTGYDNAVALPAGGRGDEEELQKENNKNVASSKGTITLSVTSSKPETGEVIGVFQSLQPSDTDLGAKVPKDVKIEGVWYAQLEQQ", "length": 332, "molWeight": 35171, "crc64": "B15507F5835117FF", "md5": "0E96CB0A466AE6DEA40298A408A38DC8"}}
{"primaryAccession": "P15478", "text": "This is Patatin-T5 protein, from Potato, contains 386 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P15478", "organism_name": "Potato", "protein_name": "Patatin-T5", "length": 386, "firstPublicDate": "1990-04-01", "FUNCTION": "Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the patatin family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATTNSFTILIFMILATTSSTFATLGEMVTVLSIDGGGIKGIIPATILEFLEGQLQEVDNNTDARLADYFDVIGGTSTGGLLTAMITTPNETNRPFAAAKDIVPFYFEHGPKIFQSSGSIFGPKYDGKYLMQVLQEKLGETRVHQALTEVAISSFDIKTNKPVIFTKSNLAKSPELDAKMYDICYSTAAAPTFFPPHYFATNTSNGDKYEFNLVDGAVATVDDPALLSISVATKLAQVDPKFASIKSLNYKQMLLLSLGTGTTSEFDKTYTAEETAKWGTARWMLVIQKMTSAASSYMTDYYLSTAFQALDSQNNYLRVQENALTGTTTELDDASEANMQLLVQVGEDLLKKSVSKDNPETYEEALKRFAKLLSDRKKLRANKASY", "length": 386, "molWeight": 42338, "crc64": "E7F7FAD1A04A1000", "md5": "C35B575BD3A137A969B434C8D085D0FF"}}
{"primaryAccession": "P16260", "text": "This is Solute carrier family 25 member 16 protein, from Human, contains 332 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P16260", "organism_name": "Human", "protein_name": "Solute carrier family 25 member 16", "length": 332, "firstPublicDate": "1990-08-01", "FUNCTION": "May be involved in the transport of coenzyme A in the mitochondrial matrix (PubMed:11158296), Very little is known about the physiological function of this carrier (PubMed:11158296)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAATAAAALAAADPPPAMPQAAGAGGPTTRRDFYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN", "length": 332, "molWeight": 36224, "crc64": "71C2C3D413F80246", "md5": "925C7B8A2BF2AF616E99EAA83B5892DA"}}
{"primaryAccession": "P19269", "text": "This is Alpha-amylase 1 protein, from Yeast, contains 512 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P19269", "organism_name": "Yeast", "protein_name": "Alpha-amylase 1", "length": 512, "firstPublicDate": "1990-11-01", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 13 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRFSTEGFTSKVVAAILAFSRLVSAQPIIFDMRDVSSSADKWKDQSIYQIVTDRFARSDGSTTADCLVSDRKYCGGSYKGIIDKLDYIQGMGFTAIWISPVVEQIPDNTAYGYAYHGYWMKNIDELNTNFGTADELKQLASELHSRSMLLMVDVVYNHYAWNGDGSSVDYSSFTPFNQQSYFHDYCLITNYNDQTNVEDCWEGDTEVSLPDLSTEDNEVIGVFQTWVSDFVQNYSIDGLRIDSAKHVDTASLTKFEDASGVYNLGEVYQGDPTYTCPYQNYMKGVTNYPLYYPVYRFFSDTSATSSELTSMISTLQSSCSDVSLLGNFIENHDQVRFPSVTSDTSLIKNDMAFIILGDGIPIIYYGQEQGLNGGSDPANREALWLSGYNTDSEYYELISKLNQIRNQAIKKDSAYSTYKSSVVSSSDHYIATRKGSDANQLISIFNNLGSNGSQDITVSNTGYSSGDKVIDIISCNSVLAGDSGSLSVSISGGMPQVYAPSSVLSGSGICNQ", "length": 512, "molWeight": 56527, "crc64": "857552B2CF60F965", "md5": "FAE13DAF8D950F228C439E965EE8A717"}}
{"primaryAccession": "P20084", "text": "This is Large ribosomal subunit protein uL30m protein, from Baker's yeast, contains 86 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P20084", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein uL30m", "length": 86, "firstPublicDate": "1991-02-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL30 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVFYKVTLSRSLIGVPHTTKSIVKSLGLGKRGSIVYKKVNPAIAGSLAKVKELVKVEVTEHELTPSQQRELRKSNPGFIVEKRTID", "length": 86, "molWeight": 9531, "crc64": "203CFC97F86E4314", "md5": "7806F93B68740EB6A5E8D27F8AE9FA78"}}
{"primaryAccession": "P21771", "text": "This is Small ribosomal subunit protein uS15m protein, from Baker's yeast, contains 286 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P21771", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein uS15m", "length": 286, "firstPublicDate": "1991-05-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uS15 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSIVGRNAILNLRISLCPLFMGKRSFVSSPVSNSAKAVKFLKAQRRKQKNEAKQATLKASTDKVDPVLGRADTPFITRIMAELKEPLVLSKGYNIEEVDKFLAAIESAKRERAELSGLNTEVVGIEDIEKLEDRREAILRILSMRNSENKNAIKMAVELARKEFERFPGDTGSSEVQAACMTVRIQNMANHIKEHRKDFANTRNLRILVQQRQAILRYLKRDNPEKYYWTIQKLGLNDAAITDEFNMDRRYMQDYEFFGDKILIRDSKKVANQKRKEIRKQKRATF", "length": 286, "molWeight": 33057, "crc64": "A3134D0896DB4CF2", "md5": "C14F1412347A7E74E2E9F7349E0236A4"}}
{"primaryAccession": "P23248", "text": "This is Small ribosomal subunit protein eS1B protein, from Baker's yeast, contains 255 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P23248", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS1B", "length": 255, "firstPublicDate": "1991-11-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAVGKNKRLSRGKKGLKKKVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKNASDALKGRVVEVCLADLQGSEDHSFRKVKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTREVQNSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGEEKGKKVSGFKDEVLETV", "length": 255, "molWeight": 28812, "crc64": "192A913E3AD5C7DE", "md5": "71349D066F701B5B0B62303BCAC711D4"}}
{"primaryAccession": "P23369", "text": "This is Large ribosomal subunit protein mL59 protein, from Baker's yeast, contains 157 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P23369", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein mL59", "length": 157, "firstPublicDate": "1991-11-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mL59 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSYKQYFDSLPLKLKSFFQRYPPSIKYSPVSTSTKAINANPFLPNKHPVTQRFHDPKYSLRRMSDVYKLALRYGVEEFLPPIENTKKLFFEEKYNKKTLMKGVLLPKGHKHELKLNEKLKKREEALKKVDELIASKKGSKYAKRVEKMKKNQSIGWF", "length": 157, "molWeight": 18587, "crc64": "DAB3B47998D6CEEB", "md5": "DCBAAB484711ED133ACD313B4724B0CE"}}
{"primaryAccession": "P23432", "text": "This is Glucan endo-1,3-beta-glucosidase protein, from Common tobacco, contains 351 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P23432", "organism_name": "Common tobacco", "protein_name": "Glucan endo-1,3-beta-glucosidase", "length": 351, "firstPublicDate": "1991-11-01", "FUNCTION": "Implicated in the defense of plants against pathogens", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 17 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALWYLFNKRSLGAAVLILVGLLMCNIQMTGAQSNIGVCYGKIANNLPSEQDVINLYKANGIRKMRIYNSDTNIFKSLNGSNIEIILDVPNQDLEALANSSIANGWVQDNIRSHFPYVKFKYISIGNEVSPSNNGQYSQFLLHAMENVYNALAAAGLQDKIKVTTATYSGLLANTYPPKDSIFREEFKSFINPIIEFLARNNLPLLANIYPYFGHIYNTVDVPLSYALFNQQGTNSTGYQNLFDALLDSIYFAVEKAGGPNVEIIVSESGWPSEGNSAATIENAQTYYRNLVNHVKGGAGTPKKPGRIVETYLFAMFDENEKNGEVTEKHFGLFYPNRTAKYQLNFMYSDT", "length": 351, "molWeight": 39186, "crc64": "5B8B82C3E8C71F39", "md5": "AC7E6859F7D78893A3B2D4EAA4018675"}}
{"primaryAccession": "P23433", "text": "This is Glucan endo-1,3-beta-glucosidase protein, from Common tobacco, contains 351 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P23433", "organism_name": "Common tobacco", "protein_name": "Glucan endo-1,3-beta-glucosidase", "length": 351, "firstPublicDate": "1991-11-01", "FUNCTION": "Implicated in the defense of plants against pathogens", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 17 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALWYLFNKRSLGAAVLILVGLLMCNIQITGAQSNIGVCYGEIANNLPSEQDVINLYKANGIRKMRIYYPDTNIFKALNGSNIEIILEVPNQDLEALANSSIANGWVQDNIRSHFPYVKFKYISIGNEVSPTNNGQYSQFLLHAMKNVYNALAAAGLQDKIKVSTATYSGLLANTYPPKDSIFREELKSFINPIIEFLARNNLPLLANIYPYFGHIYNTVDVPLSYALFNQQETNSTGYQNLFDALLDSIYFAVEKAGGPNVEIIVSESGWPSEGNSAATIENAQTYYRNLVNHVKGGAGTPKKPGRIIETYLFAMFDENEKQGEITEKHFGLFYPNRAAKYQLNFMYSDS", "length": 351, "molWeight": 39262, "crc64": "C13273CFA59A3F8E", "md5": "367CF2A24173C833D642FC44DCC9E1C9"}}
{"primaryAccession": "P23501", "text": "This is Dihydrosphingosine 1-phosphate phosphatase YSR3 protein, from Baker's yeast, contains 404 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P23501", "organism_name": "Baker's yeast", "protein_name": "Dihydrosphingosine 1-phosphate phosphatase YSR3", "length": 404, "firstPublicDate": "1991-11-01", "FUNCTION": "Dihydrosphingosine 1-phosphate phosphatase required for efficient ceramide synthesis from exogenous sphingoid bases (PubMed:10477278, PubMed:10563329, PubMed:10856228, PubMed:9353337, PubMed:9419344), Involved in endocytosis and calcium-mediated signaling (PubMed:10856228)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the type 2 lipid phosphate phosphatase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTIIQTVTELGVTEDTIKVQMAPSGGKHLLADPGNHPAEHFESQMSWLRFQTRQYLTRFTDNQSDFVHSLQKKHRTPFRDVYFKYTSLMGSHMFYVIVLPMPVWLGYRDLTRDMIYVLGYSIYLSGYLKDYWCLPRPKSPPVDRITLSEYTTKEYGAPSSHSANATAVSLLFFWRICLSDTLVWPTKLLLLSLVIFYYLTLVFGRVYCGMHGMLDLFSGAAVGAICFFIRIWVVHALRNFQIGEHLWFPLLSVAWGLFILFNHVRPIDECPCFEDSVAFIGVVSGLDCSDWLTERYGWNLVCSRYASCGSKVFLRPLVGVASVIVWKDVISKTAVYTLLIKLLRFHDDRSEKVHFHNETSEEEECLLYSGVSKVEIVGRFLIYAGIPTTVFLLCPVFFTWTNLR", "length": 404, "molWeight": 46488, "crc64": "0CDB272FBF868BF8", "md5": "D93971B9978F36F2BA36A4C1179A41CB"}}
{"primaryAccession": "P25107", "text": "This is Parathyroid hormone/parathyroid hormone-related peptide receptor protein, from North American opossum, contains 585 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25107", "organism_name": "North American opossum", "protein_name": "Parathyroid hormone/parathyroid hormone-related peptide receptor", "length": 585, "firstPublicDate": "1992-05-01", "FUNCTION": "Receptor for parathyroid hormone and for parathyroid hormone-related peptide, The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGAPRISHSLALLLCCSVLSSVYALVDADDVITKEEQIILLRNAQAQCEQRLKEVLRVPELAESAKDWMSRSAKTKKEKPAEKLYSQAEESREVSDRSRLQDGFCLPEWDNIVCWPAGVPGKVVAVPCPDYIYDFNHKGRAYRRCDSNGSWELVPGNNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFVSFMLRAVSIFIKDAVLYSGVSTDEIERITEEELRAFTEPPPADKAGFVGCRVAVTVFLYFLTTNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTLFGWGLPAVFVAVWVTVRATLANTECWDLSSGNKKWIIQVPILAAIVVNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGILWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSTYSYGPMVSHTSVTNVGPRGGLALSLSPRLAPGAGASANGHHQLPGYVKHGSISENSLPSSGPEPGTKDDGYLNGSGLYEPMVGEQPPPLLEEERETVM", "length": 585, "molWeight": 65963, "crc64": "34900384CD6DF477", "md5": "6DF3334246DD591953341F2281BBA3C5"}}
{"primaryAccession": "P25338", "text": "This is 2-hydroxy-palmitic acid dioxygenase MPO1 protein, from Baker's yeast, contains 174 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25338", "organism_name": "Baker's yeast", "protein_name": "2-hydroxy-palmitic acid dioxygenase MPO1", "length": 174, "firstPublicDate": "1992-05-01", "FUNCTION": "Dioxygenase that catalyzes the alpha-oxidation of 2-hydroxy fatty acids in an iron-dependent manner (PubMed:30530523), Involved in metabolism of phytosphingosine and is required for proper endoplasmic reticulum stress response (PubMed:25345524, PubMed:30530523)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the MPO1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGEGLLDLRSQLGFYKFYHHNPKNVLIHSIFVPTILFSGSCMLHRVKIYQSISLTAVLSVLFSIFYCLLYLPTGLLAGVLLLLLNLALIDHRVDLTFKQELGLFTIGWIFQFVGHGVFEKRRPALIDNLVQSLVLAPYFIMFEFLFKLGFMPRLKATLEHDLEIKQRNLRMQRQ", "length": 174, "molWeight": 20173, "crc64": "C6C5DF3C6EDBD3B1", "md5": "366EA85E5589964FBF50B6D274FAB923"}}
{"primaryAccession": "P25625", "text": "This is Protein PER1 protein, from Baker's yeast, contains 357 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25625", "organism_name": "Baker's yeast", "protein_name": "Protein PER1", "length": 357, "firstPublicDate": "1992-05-01", "FUNCTION": "Involved in the lipid remodeling steps of GPI-anchor maturation, Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins, Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI, Required for efficient transport of GPI-anchor proteins", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the PGAP3/PER1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRLAVVVTLLVHCFLVTCSPGDNLDEFIDCTYACEYNRRCPNSQINYIDPETNMFHDIEFFDTPPLYSKLLFWDCISDCDYQCQHIITRWRIDEEEEIYQFHGKWPFLRVLGTQEFFSTIFSIGNFIPHYKGFVKFSRIIREEGDRRRKNSRSILIWNYLYVTVAGMLAWTASSVFHCRDLIITEKLDYFFAGLTVLTGFHAIFARMTSMFLYPKIAQAFTASVAAIFALHILRLYVDWSYTYNMRFNIFFGVLQYILLIMLSCQNYHALQKQKLMGEFKKTAYSSFKRQIFKLCVIPILLVIVTTMAMSLELFDFFSYEWQIDAHALWHLCTIWPSWVLYDFFLEDYAYWGNRQLY", "length": 357, "molWeight": 42541, "crc64": "6841B84BBFAF9187", "md5": "0B668D4C088200A1424EC4FD79DD5538"}}
{"primaryAccession": "P25626", "text": "This is Large ribosomal subunit protein bL19m protein, from Baker's yeast, contains 169 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25626", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein bL19m", "length": 169, "firstPublicDate": "1992-05-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:25609543, PubMed:24675956), bL19m is essential for respiration (PubMed:8771712)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL19 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MWSRNVRLLGSWTRSYMVPATKRKTIPVYPPVQRIASSQIMKQVALSEIESLDPGAVKRKLISKKNKDRLKAGDVVRIVYDSSKCSYDTFVGYILSIDRKQLVQDASLLLRNQIAKTAVEIRVPLFSPLIERIDLLTPHVSSRQRNKHYYIRGTRLDVGDLEAGLRRKK", "length": 169, "molWeight": 19394, "crc64": "56C79944D654FA21", "md5": "547EF2388E21CF279F310B90FAED7093"}}
{"primaryAccession": "P25931", "text": "This is RYamide receptor protein, from Fruit fly, contains 464 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25931", "organism_name": "Fruit fly", "protein_name": "RYamide receptor", "length": 464, "firstPublicDate": "1992-05-01", "FUNCTION": "Receptor for the neuropeptides RYamide-1 and RYamide-2 (PubMed:21843505, PubMed:21704020), The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system (PubMed:21843505, PubMed:21704020), RYamide signaling may suppress feeding behavior (PubMed:21704020)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEHHNSHLLPGGSEKMYYIAHQQPMLRNEDDNYQEGYFIRPDPASLIYNTTALPADDEGSNYGYGSTTTLSGLQFETYNITVMMNFSCDDYDLLSEDMWSSAYFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQLLLNDEEFAHWDPLPYVWFAFHWLAMSHCCYNPIIYCYMNARFRSGFVQLMHRMPGLRRWCCLRSVGDRMNATSGTGPALPLNRMNTSTTYISARRKPRATSLRANPLSCGETSPLR", "length": 464, "molWeight": 53524, "crc64": "CA8DBC202259BBFF", "md5": "C2F66B7D6AEDDF959A1A68E2D8A06912"}}
{"primaryAccession": "P27684", "text": "This is Large ribosomal subunit protein cL37 alpha protein, from Spinach, contains 142 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P27684", "organism_name": "Spinach", "protein_name": "Large ribosomal subunit protein cL37 alpha", "length": 142, "firstPublicDate": "1992-08-01", "FUNCTION": "Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the chloroplast-specific ribosomal protein cL37 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALLSPLLSLSSVPPITSIAVSSSSFPIKLQNVSVALLPSFGQRLVAHGPVIAQKRGTVVAMVSAAAEETAGEDGDQSKVEEANISVQNLPLESKLQLKLEQKIKMKMAKKIRLRRNRLMRKRKLRKRGAWPPSKMKKLKNV", "length": 142, "molWeight": 15621, "crc64": "87425931C3E4F93F", "md5": "91B713082D5D0287AF1E947D06E1BCC5"}}
{"primaryAccession": "P27929", "text": "This is Small ribosomal subunit protein uS4m protein, from Baker's yeast, contains 486 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P27929", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein uS4m", "length": 486, "firstPublicDate": "1992-08-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uS4 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPRKANLLKSLARGRVRTSFNKYNLFNLYKKGGVDLKSKSLYQQKWTAKQETRAYHGEHLTEKRWQTVFKPKLDSVAQLDASLRGGEIKETPFLLQTFAVLEKRLDFALFRAMFASSVRQARQFILHGNVRVNGVKIKHPSYTLKPGDMFSVKPDKVLEALGAKKPSFQEALKIDKTQIVLWNKYVKEAKTEPKEVWEKKLENFEKMSDSNPKKLQFQEFLRQYNKNLESQQYNALKGCTQEGILRKLLNVEKEIGKSNNEPLSIDELKQGLPEIQDSQLLESLNNAYQEFFKSGEIRREIISKCQPDELISLATEMMNPNETTKKELSDGAKSALRSGKRIIAESVKLWTKNITDHFKTRMSDISDGSLTFDPKWAKNLKYHDPIKLSELEGDEPKARKLINLPWQKNYVYGRQDPKKPFFTPWKPRPFLSPFAILPHHLEISFKTCHAVYLRDPVARPGQSEVISPFDVPVHERAYMYYLRNGK", "length": 486, "molWeight": 56356, "crc64": "4A5CB85B354955D1", "md5": "195EC42FDE9A9D84028F04CB449F4E80"}}
{"primaryAccession": "P29786", "text": "This is Trypsin 3A1 protein, from Yellowfever mosquito, contains 254 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P29786", "organism_name": "Yellowfever mosquito", "protein_name": "Trypsin 3A1", "length": 254, "firstPublicDate": "1993-04-01", "FUNCTION": "Major function may be to aid in digestion of the blood meal", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNQFLFVSFCALLGLSQVSAATLSSGRIVGGFQIDIAEVPHQVSLQRSGRHFCGGSIISPRWVLTAAHCTTNTDPAAYTIRAGSTDRTNGGIIVKVKSVIPHPQYNGDTYNYDFSLLELDESIGFSRSIEAIALPEASETVADGAMCTVSGWGDTKNVFEMNTLLRAVNVPSYNQAECAAALVNVVPVTEQMICAGYAAGGKDSCQGDSGGPLVSGDKLVGVVSWGKGCALPNLPGVYARVSTVRQWIREVSEV", "length": 254, "molWeight": 26852, "crc64": "8127EBC9C523FAFE", "md5": "1420C5ECF99673DE2ACFFA33CDC3BB61"}}
{"primaryAccession": "P30409", "text": "This is CD9 antigen protein, from Green monkey, contains 228 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30409", "organism_name": "Green monkey", "protein_name": "CD9 antigen", "length": 228, "firstPublicDate": "1993-04-01", "FUNCTION": "Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity), Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity), In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity), In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (By similarity), Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity), Acts as a receptor for PSG17 (By similarity), Involved in platelet activation and aggregation (By similarity), Regulates paranodal junction formation (By similarity), Involved in cell adhesion, cell motility and tumor metastasis (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the tetraspanin (TM4SF) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDTYNKLKTKDEPQRETLKAIHYALDCCGLAGGVEQFISDICPKKDVLETFTIKSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRNREMV", "length": 228, "molWeight": 25431, "crc64": "FBE3298BAFAF6B7A", "md5": "CA30941B57E1EE7E36DA20E7507B68F3"}}
{"primaryAccession": "P30627", "text": "This is Globin-like protein protein, from Caenorhabditis elegans, contains 159 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30627", "organism_name": "Caenorhabditis elegans", "protein_name": "Globin-like protein", "length": 159, "firstPublicDate": "1993-04-01", "FUNCTION": "May be a globin and may play a role in oxygen transport", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the globin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSMNRQEISDLCVKSLEGRMVGTEAQNIENGNAFYRYFFTNFPDLRVYFKGAEKYTADDVKKSERFDKQGQRILLACHLLANVYTNEEVFKGYVRETINRHRIYKMDPALWMAFFTVFTGYLESVGCLNDQQKAAWMALGKEFNAESQTHLKNSNLPHV", "length": 159, "molWeight": 18501, "crc64": "0C2E473C56F59CFE", "md5": "3EB15FBCFF293A8C95C9D35A26EE27B6"}}
{"primaryAccession": "P32307", "text": "This is Vasopressin V2 receptor protein, from Pig, contains 370 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32307", "organism_name": "Pig", "protein_name": "Vasopressin V2 receptor", "length": 370, "firstPublicDate": "1993-10-01", "FUNCTION": "Receptor for arginine vasopressin, The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:8393786), Involved in renal water reabsorption (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPAERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATASSFSARDTSS", "length": 370, "molWeight": 40537, "crc64": "18079C128B689F2F", "md5": "432EEB39DFA3DDCE38D22EDD4A008253"}}
{"primaryAccession": "P32837", "text": "This is GABA-specific permease protein, from Baker's yeast, contains 571 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32837", "organism_name": "Baker's yeast", "protein_name": "GABA-specific permease", "length": 571, "firstPublicDate": "1993-10-01", "FUNCTION": "Required for high-affinity, high-specificity GABA transport, Also transports putrescine", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the amino acid-polyamine-organocation (APC) superfamily, Amino acid/choline transporter (ACT) (TC 2,A,3,4) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSMSSKNENKISVEQRISTDIGQAYQLQGLGSNLRSIRSKTGAGEVNYIDAAKSVNDNQLLAEIGYKQELKRQFSTLQVFGIAFSIMGLLPSIASVMGGGLGGGPATLVWGWFVAAFFILLVGITMAEHASSIPTAGGLYYWTYYYAPEGYKEIISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVTLTKDGNFEVTSGKLYGIFAGAVVVMCICTCVASGAIARLQTLSIFANLFIIVLLFIALPIGTKHRMGGFNDGDFIFGKYENLSDWNNGWQFCLAGFMPAVWTIGSFDSCVHQSEEAKDAKKSVPIGIISSIAVCWILGWLIIICLMACINPDIDSVLDSKYGFALAQIIYDSLGKKWAIAFMSLIAFCQFLMGASITTAVSRQVWAFSRDNGLPLSKYIKRVDSKYSVPFFAILAACVGSLILGLLCLIDDAATDALFSLAVAGNNLAWSTPTVFRLTSGRDLFRPGPFYLGKIWSPIVAWTGVAFQLFIIILVMFPSQQHGITKSTMNYACVIGPGIWILAGIYYKVYKKKYYHGPATNLSDDDYTEAVGADVIDTIMSKQEP", "length": 571, "molWeight": 61873, "crc64": "051B5828654EC784", "md5": "D4B01B5AD28E5756A8E8175C6FE6A958"}}
{"primaryAccession": "P32907", "text": "This is Ammonia transport outward protein 2 protein, from Baker's yeast, contains 282 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32907", "organism_name": "Baker's yeast", "protein_name": "Ammonia transport outward protein 2", "length": 282, "firstPublicDate": "1993-10-01", "FUNCTION": "Transporter protein required for ammonia export, Involved in acetate resistance", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the acetate uptake transporter (AceTr) (TC 2,A,96) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSDREQSSGNTAFENPKALDSSEGEFISENNDQSRHSQESICKIYTAGKNNEYIYIGRQKFLRDDLFEAFGGTLNPGLAPAPVHKFANPAPLGLSGFALTTFVLSMFNARAQGITIPNVVVGCAMFYGGLVQLIAGIWEIALENTFGGTALCSFGGFWLSFGAIYIPWFGILDAYKDKESDLGNALGFYLLGWALFTFGLSVCTMKSTIMFFALFFLLAVTFLLLSIANFTGEVGVTRAGGVLGVIVAFIAWYNAYAGIATRQNSYIMVHPFALPSNDKVFF", "length": 282, "molWeight": 30701, "crc64": "F5E20F9324CE8199", "md5": "378E73001AFFC61AF513A5DC8B3CA08A"}}
{"primaryAccession": "P33417", "text": "This is Intrastrand cross-link recognition protein protein, from Baker's yeast, contains 597 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P33417", "organism_name": "Baker's yeast", "protein_name": "Intrastrand cross-link recognition protein", "length": 597, "firstPublicDate": "1994-02-01", "FUNCTION": "Binds to platinated DNA and confers sensitivity to the anticancer drug cisplatin, Activate the expression of the COX5B gene", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNTGISPKQDDASNSNLLNIGQDHSLQYQGLEHNDSQYRDASHQTPHQYLNQFQAQPQQQQQQQQQQQQQQQQAPYQGHFQQSPQQQQQNVYYPLPPQSLTQPTSQSQQQQQQQQQQQYANSNSNSNNNVNVNALPQDFGYMQQTGSGQNYPTINQQQFSEFYNSFLSHLTQKQTNPSVTGTGASSNNNSNNNNVSSGNNSTSSNPAQLAASQLNPATAAAAAANNAAGPASYLSQLPQVQRYYPNNMNALSSLLDPSSAGNAAGNANTATHPGLLPPNLQPQLTHHQQQMQQQLQLQQQQQLQQQQQLQQQHQLQQQQQLQQQHHHLQQQQQQQQHPVVKKLSSTQSRIERRKQLKKQGPKRPSSAYFLFSMSIRNELLQQFPEAKVPELSKLASARWKELTDDQKKPFYEEFRTNWEKYRVVRDAYEKTLPPKRPSGPFIQFTQEIRPTVVKENPDKGLIEITKIIGERWRELDPAKKAEYTETYKKRLKEWESCYPDENDPNGNPTGHSHKAMNMNLNMDTKIMENQDSIEHITANAIDSVTGSNSNSTNPNTPVSPPISLQQQPLQQQQQQQQQQQHMLLADPTTNGSIIKNE", "length": 597, "molWeight": 67856, "crc64": "AF3B705AA2C5AC74", "md5": "9968CB042667F5EE8BEEADAB69ABBF0E"}}
{"primaryAccession": "P33893", "text": "This is Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial protein, from Baker's yeast, contains 541 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P33893", "organism_name": "Baker's yeast", "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "length": 541, "firstPublicDate": "1994-02-01", "FUNCTION": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria, The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the GatB/GatE family, GatB subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRLARFYSLARTKAIHSHGAPFRPEYALKCGLEIHTQLNTKNKLFSQSTNSATSLVDAPNHHTSYYDIALPGTQPVLNLEAILFAMKLSLALGSQVNSISQFDRKHYFYGDQPQGYQLTQHYRPFARGGKINLSKELDDIDESAKEIGILQLQIEQDTGKSHYTETDKDVITLVDLNRSNVPLIELVTKPDFSDIKQVRAFIKKYQNLVRHLHISSGDLETGAMRVDVNLSINEYARVELKNLPNTSSIINAIKYEYQRQVELISVGDTSSLMEPETRGWTGSSTVKLRSKETTIDYRYMPDPELPYINLAPDVISGVRGLMPQLPDDIMRILMKKPYQLSLKDAKILTYNSNQNDMYNHEALRSYYLDTFREFSKLAGERSNAKLPTNWIIHEFLGDLNKLQIPLAKAKEILPPPVFAQFLKLLHEEVISATSGKMLLFHILENFEQSNCQDLSIPDFSKLIEKFELHAINQVDPQELMDLCNDVIAQHTDDTFIRNLVTGKKKSSLKFLIGQGMRRSQGRIKANEFEKKFKEILNIQW", "length": 541, "molWeight": 61869, "crc64": "F426E82F1532B07D", "md5": "2386BE3275F1F3DB5D68431853DE0532"}}
{"primaryAccession": "P35035", "text": "This is Trypsin-1 protein, from African malaria mosquito, contains 274 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35035", "organism_name": "African malaria mosquito", "protein_name": "Trypsin-1", "length": 274, "firstPublicDate": "1994-02-01", "FUNCTION": "Major function may be to aid in digestion of the blood meal", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSNKIAILLAVLVAVVACAEAQANQRHRLVRPSPSFSPRPRYAVGQRIVGGFEIDVSDAPYQVSLQYNKRHNCGGSVLSSKWVLTAAHCTAGASPSSLTVRLGTSRHASGGTVVRVARVVQHPKYDSSSIDFDYSLLELEDELTFSDSVQPVGLPKQDETVKDGTMTTVSGWGNTQSAAESNAVLRAANVPTVNQKECNKAYSEFGGVTDRMLCAGYQQGGKDACQGDSGGPLVADGKLVGVVSWGYGCAQAGYPGVYSRVAVVRDWVRENSGV", "length": 274, "molWeight": 29057, "crc64": "7055CA51C6CEF3F8", "md5": "A7269C4E11B91BA2B2204953474B6887"}}
{"primaryAccession": "P35036", "text": "This is Trypsin-2 protein, from African malaria mosquito, contains 277 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35036", "organism_name": "African malaria mosquito", "protein_name": "Trypsin-2", "length": 277, "firstPublicDate": "1994-02-01", "FUNCTION": "Major function may be to aid in digestion of the blood meal", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSNKIAILLLAVVVAVVACAQAQPSRRHHLVHPLLPRFLPRLHRDSNGHRVVGGFQIDVSDAPYQVSLQYFNSHRCGGSVLDNKWVLTAAHCTQGLDPSSLAVRLGSSEHATGGTLVGVLRTVEHPQYDGNTIDYDFSLMELETELTFSDAVQPVELPEHEEPVEPGTMATVSGWGNTQSAVESSDFLRAANVPTVSHEDCSDAYMWFGEITDRMLCAGYQQGGKDACQGDSGGPLVADGKLVGVVSWGYGCAQPGYPGVYGRVASVRDWVRENSGV", "length": 277, "molWeight": 29822, "crc64": "7C1EAF6FA549B2E7", "md5": "C882AECD577F2A5CC82EE8C826B11EC2"}}
{"primaryAccession": "P35037", "text": "This is Trypsin-3 protein, from African malaria mosquito, contains 275 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35037", "organism_name": "African malaria mosquito", "protein_name": "Trypsin-3", "length": 275, "firstPublicDate": "1994-02-01", "FUNCTION": "Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MISNKIAILLAVLVVAVACAQARVALKHRSVQALPRFLPRPKYDVGHRIVGGFEIDVSETPYQVSLQYFNSHRCGGSVLNSKWILTAAHCTVNLQPSSLAVRLGSSRHASGGTVVRVARVLEHPNYDDSTIDYDFSLMELESELTFSDVVQPVSLPDQDEAVEDGTMTIVSGWGNTQSAAESNAILRAANVPTVNQKECTIAYSSSGGITDRMLCAGYKRGGKDACQGDSGGPLVVDGKLVGVVSWGFGCAMPGYPGVYARVAVVRDWVRENSGA", "length": 275, "molWeight": 29374, "crc64": "93D27A26AF4C5458", "md5": "4920A0F4EEF6722B4C1B771A1C0D84EC"}}
{"primaryAccession": "P35038", "text": "This is Trypsin-4 protein, from African malaria mosquito, contains 275 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35038", "organism_name": "African malaria mosquito", "protein_name": "Trypsin-4", "length": 275, "firstPublicDate": "1994-02-01", "FUNCTION": "Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSNKITILLAVLLAVVACAQAHASHQRRVPYPLPRFLPRPHHTVSNHRIVGGFEIDVAETPYQVSLQRSKRHICGGSVLSGKWILTAAHCTDGSQPASLTVRLGSSRHASGGSVIHVARIVQHPDYDQETIDYDYSLLELESVLTFSNKVQPIALPEQDEAVEDGIMTIVSGWGSTKSAIESNAILRAANVPTVNQDECNQAYHKSEGITERMLCAGYQQGGKDACQGDSGGPLVAEDKLIGVVSWGAGCAQPGYPGVYARVAVVRDWIRETCGV", "length": 275, "molWeight": 29608, "crc64": "AEFFEDA9F24F71C8", "md5": "980F7B7FB3359F9DC1791520227DD5B8"}}
{"primaryAccession": "P35039", "text": "This is Trypsin-5 protein, from African malaria mosquito, contains 274 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35039", "organism_name": "African malaria mosquito", "protein_name": "Trypsin-5", "length": 274, "firstPublicDate": "1994-02-01", "FUNCTION": "Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSIKFTTLLAVLFALLAYARAQAERRHKLTRPVHRFAPNRPYLAGKRIVGGFVINISDAPYQISLQYDDDHNCGGSILSSKWILTAAHCINDNAPSKPTVRVGSSKHASGGTVIRVARIVPHPMHGSKNNYDIALLELKNELTFSEKVQPIALPEQDEPIEEGTMGIVSGWGLTLSEADSNDVLRATNVPTVNQQECNKAYQSRYGGITDQMFCAGYKQGGQDTCRQDSGGPFVAKGKLIGVISWGHECALAGYPGVYARVASVRDWIRTTSGV", "length": 274, "molWeight": 29815, "crc64": "468AB656797AED8E", "md5": "724BAA9FF63BD2FAFFE37EF0D1228BC0"}}
{"primaryAccession": "P35040", "text": "This is Trypsin-6 protein, from African malaria mosquito, contains 273 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35040", "organism_name": "African malaria mosquito", "protein_name": "Trypsin-6", "length": 273, "firstPublicDate": "1994-02-01", "FUNCTION": "Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLSKFTAILLAVHIALFACALTQAEKRHKLTRPAFHPNAPYLAGKRIVGGFVIDISDAPYQISLQYNGKHHCGGSILNSKWILTAAHCIDLYSEVKPTVRVGSSEHAAGGTVLHLLRIVPHPGHSSGGNNYDIALLELECELTFNDNVQPVQLPEQDDPIDEGTMGIVSGWGMTMSAADLNAILRATNVPTVNQQECNQAYQSYGGVAEQMFCAGYKQGGTGTCRNDSGGPFVAEGKLIGVVSWSHECALAGYPGVYARVASVRDWIRETSGV", "length": 273, "molWeight": 29295, "crc64": "4A485528B7D679D1", "md5": "080C91F4488987816BA53E793E5864B9"}}
{"primaryAccession": "P35041", "text": "This is Trypsin-7 protein, from African malaria mosquito, contains 267 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35041", "organism_name": "African malaria mosquito", "protein_name": "Trypsin-7", "length": 267, "firstPublicDate": "1994-02-01", "FUNCTION": "Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSNKIAILLTVLIAVVACARAQPSRRHPLVQPRSPHGSGHRIVGGFEINVSDTPYQVSLQYINSHRCGGSVLNSKWVLTAAHCTDGLQAFTLTVRLGSSRHASSGTVVNVARIVEHPKYNEYNTDYDYALLELESELTFSDVVQPVALPEQDEAVDAGTMTIVSGWGSTKSATESNAILRAANVPTVDQEECREAYSHDAITDRMLCAGYQQGGKDACQGDSGGPLVADGKLIGVVSWGSGCAQPGYPGVYARVAVVRNWVREISGV", "length": 267, "molWeight": 28542, "crc64": "2C7FF0650E7E0F58", "md5": "8B7B34ACB9909AEF9D5ED708635AD5E4"}}
{"primaryAccession": "P35723", "text": "This is Endoplasmic reticulum transmembrane protein 1 protein, from Baker's yeast, contains 206 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35723", "organism_name": "Baker's yeast", "protein_name": "Endoplasmic reticulum transmembrane protein 1", "length": 206, "firstPublicDate": "1994-06-01", "FUNCTION": "May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the BCAP29/BCAP31 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSLYFTTLFLLLTVEMVMLFIFVLPLPFRIRRGIFSTYNQLTAKQQIKTIIFITGCLVGLLFIDSWKRSQIRVSLYHNDNSGSIGSSAVTPIQALASRAYNQRNMYISGFILYFSICIPTVMSIVKRLVKYQGLINEQEKQKLNKPSSNSKKDSNEADSTKLQEELRKKQISLEGLQKQVKNLEKYFDEKNQPGNVAAAEASKKGN", "length": 206, "molWeight": 23459, "crc64": "54182F0ECC81AA6F", "md5": "FC3DBD6C73C0E41AC387C2CC254815FA"}}
{"primaryAccession": "P35731", "text": "This is 3-oxoacyl-[acyl-carrier-protein] reductase protein, from Baker's yeast, contains 278 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35731", "organism_name": "Baker's yeast", "protein_name": "3-oxoacyl-[acyl-carrier-protein] reductase", "length": 278, "firstPublicDate": "1994-06-01", "FUNCTION": "Involved in biosynthesis of fatty acids in mitochondria", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the short-chain dehydrogenases/reductases (SDR) family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET", "length": 278, "molWeight": 31184, "crc64": "62FC3BC347D3E933", "md5": "575F272E569DE3B9ECCE441239C4FFC7"}}
{"primaryAccession": "P36008", "text": "This is Elongation factor 1-gamma 2 protein, from Baker's yeast, contains 412 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36008", "organism_name": "Baker's yeast", "protein_name": "Elongation factor 1-gamma 2", "length": 412, "firstPublicDate": "1994-06-01", "FUNCTION": "Subunit of the eukaryotic elongation factor 1 complex (eEF1), Probably plays a role in anchoring the complex to other cellular components (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSQGTLYINRSPRNYASEALISYFKLDVKIVDLEQSSEFASLFPLKQAPAFLGPKGLKLTEALAIQFYLANQVADEKERARLLGSDVIEKSQILRWASLANSDVMSNIARPFLSFKGLIPYNKKDVDACFVKIDNLAAVFDARLRDYTFVATENISLGDLHAAGSWAFGLATILGPEWRAKHPHLMRWFNTVAASPIVKTPFAEVKLAEKALTYTPPKKQKAEKPKAEKSKAEKKKDEAKPADDAAPAKKPKHPLEALGKSTFVLDDWKRKYSNDDTRPVALPWFWEHYNPEEYSIWKVGYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQDFAPAFDVAPDWESYEYTKLDPTKEEDKEFVNNMWAWDKPVVVNGEDKEIVDGKVLK", "length": 412, "molWeight": 46520, "crc64": "42F1B5B25EF66189", "md5": "748BAD3DDB7F25DDEDC1F01B7A52649C"}}
{"primaryAccession": "P36062", "text": "This is Vacuolar amino acid transporter 3 protein, from Baker's yeast, contains 692 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36062", "organism_name": "Baker's yeast", "protein_name": "Vacuolar amino acid transporter 3", "length": 692, "firstPublicDate": "1994-06-01", "FUNCTION": "Involved in amino acid efflux from the vacuole to the cytoplasm, Capable of transporting large neutral amino acids including tyrosine, glutamine, asparagine, isoleucine and leucine", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the amino acid/polyamine transporter 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNGKEVSSGSGRTQSNNNKKNNNGGSTGISHASGSPLTDGNGGNSNGNSRSRSRSRKSSGTTGGLLKKPPLLVNNEAVHASVPDASHTSCNNGTLEVSINNPEPHVVDAVARHLIRNPSNSLQLQGGDITRDLYKWTNDHPSSPSQYQYPSQPALSTSIPSQAPSFSNRKRSMSFSAASIASSSHLNNNSEANGNPLAAIGLAPAPMTHEEIRAPGGFRRSFIIQKRRKHNVDAPIPNFFTRNFIEFLTLYGHFAGEDLSEEEEEEEETEEEPEEEALETESTQLVSREHGRHPHKSSTVKAVLLLLKSFVGTGVLFLPKAFHNGGWGFSALCLLSCALISYGCFVSLITTKDKVGVDGYGDMGRILYGPKMKFAILSSIALSQIGFSAAYTVFTATNLQVFSENFFHLKPGSISLATYIFAQVLIFVPLSLTRNIAKLSGTALIADLFILLGLVYVYVYSIYYIAVNGVASDTMLMFNKADWSLFIGTAIFTFEGIGLLIPIQESMKHPKHFRPSLSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLNFPQDTSYTLTVQLLYALAILLSTPLQLFPAIRILENWTFPSNASGKYNPKVKWLKNYFRCAIVVLTSILAWVGANDLDKFVSLVGSFACIPLIYIYPPLLHYKASILSGTSRARLLLDLIVIVFGVAVMAYTSWQTIKMWSQ", "length": 692, "molWeight": 75459, "crc64": "379054D69094A0F5", "md5": "2A5CB155FC4B96FEAFDF5178B57F0EC5"}}
{"primaryAccession": "P36080", "text": "This is Ribosomal RNA-processing protein 14 protein, from Baker's yeast, contains 434 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36080", "organism_name": "Baker's yeast", "protein_name": "Ribosomal RNA-processing protein 14", "length": 434, "firstPublicDate": "1994-06-01", "FUNCTION": "Involved in ribosome biogenesis and cell polarity, Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in correct positioning of the mitotic spindle during mitosis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SURF6 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSNSLEERLRANSSAFDGLLALIPAKYYYDEKSQEQWKAKKKTKEQSKNDKLKKLDPEQRDDETSSTLEVMKKKEKDAKPVVLPGEKFKHMKMQKQKEATSKVEGDSDLNVEVNDPMIIAPDEDEEEEEDIKVIFDDEGNEIPLESKKDTTEPDRSVEKKSITEEEKLQRKKNLEALRSKLQAKISDMKSKRKAPGSREAILAQRKRKEELKKRKRLESEQEQDQDEIASDSDMEDIDSDLENNSKKRFKKGKKDSEINADGVMFQNIIFDDGARATSDLQRLRKAGRTKGPAKNDVKSHLKLLEAKKNKMEAKDELEQIKQKEKEKWQKAMLQAEGIKIRDDEKLLRKAIKRKEAQKRKSAIEWSERKRVVEDTISERQKRREENLRIRKDNKGKKRNKQEKMKRKYVGSAVPKKRAGFEGRLKTGKKKGGPK", "length": 434, "molWeight": 50482, "crc64": "BCEDE9F10A466E6E", "md5": "30BA91AC59ABF581192A480B30AA5318"}}
{"primaryAccession": "P36091", "text": "This is Mannan endo-1,6-alpha-mannosidase DCW1 protein, from Baker's yeast, contains 449 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36091", "organism_name": "Baker's yeast", "protein_name": "Mannan endo-1,6-alpha-mannosidase DCW1", "length": 449, "firstPublicDate": "1994-06-01", "FUNCTION": "Required for normal synthesis of the cell wall", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glycosyl hydrolase 76 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLVNKVIGLLGVLFATRFTNAVELDLDNYESLQNATSLIAYGLMDYYTGNQYGKTVGMFSDPYYWWEAGGAWGCMLDYWFFMDNDTYNDEIIAAMIHQAGDDNDYIPLNQSTTEGNDDQAFWGIAAMTAAERNFTNPPENEPQWLYLAQAVFNTMALRWDADSCGGGLRWQIFVWNSGYDYKNTVSNGALFHIAARLARYTGNQTYVDWAEKVYEWMVGVNLISNGTYKYVYDGVSIDDNCTKVTSYQWTYNQGLLLAGSAYLYNFTGSDLWHTRTKEFLNASQVFFHDGIVYEAACQGPNSCNTDQRSFKAYFARFLGVTAQLVPETRNQIMSWLNTSAIAAAKSCSGGTDGHTCGLNWFNGTWDGMYGLGEQMSALEVMVNTRALDKPAPYTAENGGSSVGDGAAGTQAQPTNLAPLNITKGSKAGAGIITAVIGISIVACALWLVF", "length": 449, "molWeight": 49565, "crc64": "DECFE9CAFD9579D5", "md5": "41A397A33218CF06080E5B840165C49C"}}
{"primaryAccession": "P36517", "text": "This is Large ribosomal subunit protein uL29m protein, from Baker's yeast, contains 319 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36517", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein uL29m", "length": 319, "firstPublicDate": "1994-06-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL29 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MWKRSFHSQGGPLRARTKFTKPKPKQPVLPKDKIRPPTQLTHHSNNLRITEPIPPTTSNLRCPDDHPLWQFFSNKKFIRSADDLPPSSHIRPWSIPELRHKSFNDLHSLWYNCLREQNVLARENHLLKNIVGSTHDEFSELSNSIRTTMWQIRHVLNERELAYSASREFLQDESERKKFLDTLANDYFLNKDIPDDEVASMLTRFQLAIFGISETIQDNTVDINFIDGIKFLANLKLQRFKDSNDLISEISQEPITDVGESFILFTSDFEPHAVQEACVAIKDLRKSPDNKVPKLDELPTVRKYLKQLIHASSVEQATA", "length": 319, "molWeight": 36965, "crc64": "2DE880E9BFE19BC9", "md5": "39105A8E395811C87FE23199A9013498"}}
{"primaryAccession": "P36533", "text": "This is Large ribosomal subunit protein bL33m protein, from Baker's yeast, contains 70 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36533", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein bL33m", "length": 70, "firstPublicDate": "1994-06-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL33 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVKVKSKNSVIKLLSTAASGYSRYISIKKGAPLVTQVRYDPVVKRHVLFKEAKKRKVAERKPLDFLRTAK", "length": 70, "molWeight": 7973, "crc64": "DE913D145279D61B", "md5": "8E4BBCEE83D1CC18EC1383805F33C324"}}
{"primaryAccession": "P36618", "text": "This is Cell division control protein 16 protein, from Fission yeast, contains 299 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36618", "organism_name": "Fission yeast", "protein_name": "Cell division control protein 16", "length": 299, "firstPublicDate": "1994-06-01", "FUNCTION": "Has a dual role in the cell cycle, In mitosis, it is involved in maintenance of cdc2 kinase activity, It is subsequently required for regulation of septum formation, Could be involved in maintenance of cdc2 kinase activity by preventing, directly or indirectly, the degradation of cyclin or the dephosphorylation of 'Thr-167' of cdc2", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the BUB2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPSIDCKRLQKLAPKSPENQSKCISRLRYMVMLDQVESDEGGNSSTRPYVWAVLLNAPPRNADEYIRYVRQGPSPMAQKIQNDVSRTLVVESQFHSRVSQSSLSRLLNAYVWKRGALYVQGMNVLASPFLYACKSENQAFQFFDRLLQNECPLYVLPNIDGVHRGAKLLDKCLEVLDHRLYTYLLSKGLTAKIYALPSILTLSACTAPLSEALTIWDFLFAYGIHLNILCVIAQMFIFREQLIDHPSPMTLLRTFPPLNAKNIMKITILLISKLPPELYNLLARHAWDSEAGVLIDRLT", "length": 299, "molWeight": 33989, "crc64": "8958846E4032766D", "md5": "0FDDA33545B90F592566B3A1CEDD9F0E"}}
{"primaryAccession": "P38064", "text": "This is Large ribosomal subunit protein uL16m protein, from Baker's yeast, contains 232 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38064", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein uL16m", "length": 232, "firstPublicDate": "1994-10-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL16 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFPYLTRMNLSIKMGGLTLKESSPNAFLNNTTIARRFKHEYAPRFKIVQKKQKGRVPVRTGGSIKGSTLQFGKYGLRLKSEGIRISAQQLKEADNAIMRYVRPLNNGHLWRRLCTNVAVCIKGNETRMGKGKGGFDHWMVRVPTGKILFEINGDDLHEKVAREAFRKAGTKLPGVYEFVSLDSLVRVGLHSFKNPKDDPVKNFYDENAKKPSKKYLNILKSQEPQYKLFRGR", "length": 232, "molWeight": 26518, "crc64": "6E0C11EADC4C156C", "md5": "061A76B7151021FB30D2EFE0D2217B1A"}}
{"primaryAccession": "P38126", "text": "This is Pachytene checkpoint protein 2 protein, from Baker's yeast, contains 564 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38126", "organism_name": "Baker's yeast", "protein_name": "Pachytene checkpoint protein 2", "length": 564, "firstPublicDate": "1994-10-01", "FUNCTION": "Required for the pachytene checkpoint, the meiotic checkpoint that prevents chromosome segregation when defects in recombination and synaptonemal complex formation occurred, Represses meiotic recombination in the rDNA, probably by excluding the meiosis-specific protein HOP1 from the nucleolar region", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the AAA ATPase family, PCH2 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSYIVDLQVRGSSLRVIKCMFREDEQISSLHSGSDSKQNSNKKLGEFLNLLKAVVKRKLESFPKDRLKTSIITGQELMREGQGSIEIKDPPTEAQQHLIRSLAKVLLHQFSSINGKVNTVNEGQDNLFLSLFVKKISIEQQSTSHVSIKLNFHEKINLGQHIDSILDSEETNESDTYHMGSVDEFIIYPFCCLEEQDELKNGSILSTEFDKIDLELDEDDGFEGETLNNCINSVGNFDIPLSKQTLNLVNISYLPGTTFEGQWESLYFGNNIKERLYSYATISLKIARFKQTGDSNQEDITTLITNNKLLLVHGPPGTGKTTLCKALCQKLSVRREFSDGSDTIDTNYKGIIIELSCARIFSKWFGESSKNISIVFKDIEELLKVNEGRGIFICLLIDEVEAIASSRTNLSSRNESTDGIRVVNTLLTQLDRLKKYHNFLALATSNLLDSLDDAFVDRADGVFYVGNPTAEGILHILKVCIEEMITSGIILFHARSTGVKFFNKYQDILRKIAIKCSTVDISGRTIRKLPLMCLSEYFRTFPVDDDEFVLALAMSARKLSAARK", "length": 564, "molWeight": 63460, "crc64": "9B40C41368672877", "md5": "683F98DE4EB6B10CAB820904D1EC3663"}}
{"primaryAccession": "P38166", "text": "This is Protein transport protein SFT2 protein, from Baker's yeast, contains 215 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38166", "organism_name": "Baker's yeast", "protein_name": "Protein transport protein SFT2", "length": 215, "firstPublicDate": "1994-10-01", "FUNCTION": "Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex, Can be partially replaced by GOT1", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the SFT2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSEEPPSDQVNSLRDSLNRWNQTRQQNSQGFNESAKTLFSSWADSLNTRAQDIYQTLPVSRQDLVQDQEPSWFQLSRTERMVLFVCFLLGATACFTLCTFLFPVLAAKPRKFGLLWTMGSLLFVLAFGVLMGPLAYLKHLTARERLPFSMFFFATCFMTIYFAAFSKNTVLTITCALLELVAVIYYAISYFPFGATGLRMLSSAGVNSARGVLRI", "length": 215, "molWeight": 24274, "crc64": "1BF971749814382C", "md5": "C9498814BFE2F04B8D376C47EC781595"}}
{"primaryAccession": "P38175", "text": "This is Small ribosomal subunit protein bS21m protein, from Baker's yeast, contains 177 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38175", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein bS21m", "length": 177, "firstPublicDate": "1994-10-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bS21 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLKSTLRLSRISLRRGFTTIDCLRQQNSDIDKIILNPIKLAQGSNSDRGQTSKSKTDNADILSMEIPVDMMQSAGRINKRELLSEAEIARSSVENAQMRFNSGKSIIVNKNNPAESFKRLNRIMFENNIPGDKRSQRFYMKPGKVAELKRSQRHRKEFMMGFKRLIEIVKDAKRKGY", "length": 177, "molWeight": 20395, "crc64": "EE6676C74827F189", "md5": "70FB93DF8776C4A1F8AAAF7B5D642B75"}}
{"primaryAccession": "P38204", "text": "This is RNA polymerase I-specific transcription initiation factor RRN10 protein, from Baker's yeast, contains 145 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38204", "organism_name": "Baker's yeast", "protein_name": "RNA polymerase I-specific transcription initiation factor RRN10", "length": 145, "firstPublicDate": "1994-10-01", "FUNCTION": "Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex, Together with SPT15/TBP UAF seems to stimulate basal transcription to a fully activated level", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDRNVYEACSNIIKEFGTHVVSADEVLAEKIDNAVPIPFKTREEIDADVEKDRNEGVFEGNIIPDIDLRVVHYYATQLCLNKYPHLINAFDETSLITLGLLIEKWVKDYLTSIQTEQGRQSKVIGKGPCEFISKHIDYRHAPGNI", "length": 145, "molWeight": 16505, "crc64": "970E552D55ECE41D", "md5": "23586126F60BA656C96984B7A8899BA3"}}
{"primaryAccession": "P38324", "text": "This is Structure-specific endonuclease subunit SLX1 protein, from Baker's yeast, contains 304 amino acids, has 1 SLX1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [218, 282], "description": "SLX1-type", "keyword_description": "Zinc finger", "textural_description": "SLX1-type Zinc finger"}], "meta_data": {"primaryAccession": "P38324", "organism_name": "Baker's yeast", "protein_name": "Structure-specific endonuclease subunit SLX1", "length": 304, "firstPublicDate": "1994-10-01", "FUNCTION": "Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA, Has a preference for simple Y, 5'-flap and replication fork-like structures, It cleaves the strand bearing the 5'-non-homologous arm at the branch site junction and generates ligatable, nicked products from the 5'-flap or replication fork substrates, Plays a critical role in maintaining the integrity of the ribosomal DNA (rDNA) loci, where it has a role in re-starting stalled replication forks, Has Holliday junction resolvase activity in vitro", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SLX1 family", "domain_description": {"SLX1-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSQKIQQHQFPDFYCCYLLQSINKRQSFYVGSTPNPVRRLRQHNGKLAVGGAYRTKRDGSRPWEMIMIVRGFPSKIAALQFEHAWQHGYQTHYIAEKDRVVKHKAGGRTLHHKVALMKLLLKHEFFQRMNLIVEVFNIKAWEVWKQDKFFIERDRFPINIQINENALEEPKEKTVDVLMDHSDENLKVVEAVYTKVIENERNIFETFEKKLTTGVVRCEICEKEIDYTSEEQNLKPFVALCNNKDCGCVNHLKCLHRYFLDDEQLMVGRRNLIPRGGKCPKCDMFCDWTTLVKFSTRMKLAHGK", "length": 304, "molWeight": 35857, "crc64": "4C676E877FDF7A7A", "md5": "A30554FA4FEDF7929FC53082EDF83DE6"}}
{"primaryAccession": "P38347", "text": "This is Protein-lysine N-methyltransferase EFM2 protein, from Baker's yeast, contains 419 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38347", "organism_name": "Baker's yeast", "protein_name": "Protein-lysine N-methyltransferase EFM2", "length": 419, "firstPublicDate": "1994-10-01", "FUNCTION": "S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 2 (EFT1/EFT2) at 'Lys-613' and methylates elongation factor 3A (YEF3)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the class I-like SAM-binding methyltransferase superfamily, METTL21 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFDPLDLYTPDDIQVEALQFNLAEREPKDPCSPQRDEILTAVDEEESDDDDTIIDNLDLPSVKYAPPEVILCILILLKPDRQVNFNQETGKNKSVLEVCKSHGLEPDLLKRLLTWYTEEWPNKRLNSLEKICNKIPMLRFTVSKELLLGYYTSVLKKYNNSCGLNEEIIQELLKELSSRISENCGRTAQPSIVRYFELRNLSTSIPLHEPSLTADNLGWKTWGSSLILSQLVVDHLDYLHTTNVNMLANSDIKQIKVLELGAGTGLVGLSWALKWKELYGTENIEIFVTDLPEIVTNLKKNVSLNNLGDFVQAEILDWTNPHDFIDKFGHENEFDVILIADPIYSPQHPEWVVNMISKFLAASGTCHLEIPLRAKYAKEREVLKLLLKESDLKVVEERHSEGVDDWGAVKYLYRQIVRN", "length": 419, "molWeight": 47977, "crc64": "E15B739CB94BE4A2", "md5": "7DD260481014945027761346ED51596A"}}
{"primaryAccession": "P38813", "text": "This is Protein BIG1 protein, from Baker's yeast, contains 335 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38813", "organism_name": "Baker's yeast", "protein_name": "Protein BIG1", "length": 335, "firstPublicDate": "1995-02-01", "FUNCTION": "Required for normal beta-1,6-glucan synthesis", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the BIG1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQTVLKYLLLIMCGSFCASEELQNQTNVPAIFFSYKLTPGILKYQEDYDRAVTLPRDTFIEAAEKFLGVCNADTYVFINQPGLRKLDFLEFETEFVSLQRYIRRSSTAIKFEKVDLLPQDLYYDLAEFVKEYCNVDQVLNLRGNNTEDFQPFIDSEKRVIIIEYPKLPEDTNERKEAFRHYDKYLRTILAQIPSPEQNVIYTSLNPGTTLAHESIIPIQIFPDIFDIKSRVGEVEQNNRVLDVPRLSFNDYTPRFSEPPSEYVSIFDSQLIENNRGLLQLIFTILVGYILIQFFFTKKTIVDEKITNKKDNVKQTSPQLLKKVQEIQKKPSQQVS", "length": 335, "molWeight": 39069, "crc64": "BA2D68E3A7B8884C", "md5": "A0F694DC2CDF3208828847BDB6C018B5"}}
{"primaryAccession": "P38877", "text": "This is Chromosome transmission fidelity protein 8 protein, from Baker's yeast, contains 133 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38877", "organism_name": "Baker's yeast", "protein_name": "Chromosome transmission fidelity protein 8", "length": 133, "firstPublicDate": "1995-02-01", "FUNCTION": "Essential for the fidelity of chromosome transmission, Required for the DNA replication block checkpoint, Component of the RFC-like complex CTF18-RFC which is required for efficient establishment of chromosome cohesion during S-phase and may load or unload POL30/PCNA, During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC, The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit, Dissociation of RFC from the clamp leaves the clamp encircling DNA", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CTF8 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPSVDIDASQWQKLTQSREKQTTVITPLGMMMLEIQGELELPKDFASLARRDSPNEGRFSEQDGETLIRFGSLQIDGERATLFVGKKQRLLGKVTKLDVPMGIMHFNSKDNKVELVDVMKYKVIFKDRPLPIM", "length": 133, "molWeight": 15169, "crc64": "D1E4A255B974D51F", "md5": "5D251D7A6469DEF105C407B00F3B43C6"}}
{"primaryAccession": "P38880", "text": "This is Mitochondrial distribution and morphology protein 31 protein, from Baker's yeast, contains 579 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38880", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial distribution and morphology protein 31", "length": 579, "firstPublicDate": "1995-02-01", "FUNCTION": "Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria, Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MDM31/MDM32 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSLFTRPFLRSPRQFSVARYVYWARSPALRSNLRIPSIAAASLRAYSNESKTGRDAPPDKKSKKLSNLKYITERDSLLVQTNNIFTKLKINIRWFLKKSTRPFNSDDISAFISWILVSNIFIFIFWTTTFVSLILYLINTVFAQEYLASKIGKFITKNESLSIVFESAIVPDWSSGKISFQKVFVSRRPKVSRGFTKGSQQDALQRAKLALSERILVNQQDFDNGNYTQFDLTIDQVDISLNFRKWINGKGILDEVTINGLRGVIDRTHVVWKKDDDPKNYLNVYQPGDFEISKFTMNDVLCTLYQPNGFRPFQVSIFNCDLPQLRKHWLFYDILNANNINGTYDNSMFTIHKKFRTDDQHQDPTLLWKQMTRFRVDNLDIDHLNAGIEGPFGWINEGRVNMIGDVLLPDDDAASDSLQLTEILTEIGDRLIKKAKRYTSSLPLVGPGFSPAVDEIDPNDYFIMDFSLRLYNVKAEVPLFTSGLTYINSALIRPIVGYINSHRTYIPIKCRIVKKKSDFEGSWTIYDSYLMRDLSAEAYDAFADYVADDEKRTLRLRRVGFWSLQLILQVILMSLGAIA", "length": 579, "molWeight": 66703, "crc64": "4BB155D6D88BB826", "md5": "5F53336C1AAF904AB19E5E1AFFA7DCF8"}}
{"primaryAccession": "P39543", "text": "This is Protein SOP4 protein, from Baker's yeast, contains 234 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P39543", "organism_name": "Baker's yeast", "protein_name": "Protein SOP4", "length": 234, "firstPublicDate": "1995-02-01", "FUNCTION": "Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the SOP4 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFSQIVLLLSAFIYVASATARRGTIKGRLDLAASNITGFVSTRTSFKLYQIGNFSTEYPYTSTTMFQDDEGNFEFANLPLNDGVNETTYYVMYPASMDFNLKPNRILIEFKNLENGTLQLNAFKNFFGREYFPSKDITYPEKLQSMKVHPYITVELLHKAPIRSYLQARNVSIFSTGIVGNILNSRWKLAGVITLIALVVFPIIVEKLDPETARAIREEAKRKQREKYAAVASK", "length": 234, "molWeight": 26598, "crc64": "A29CA99FA3741A41", "md5": "56EE467A3820CBD107E7859A67234A93"}}
{"primaryAccession": "P39735", "text": "This is Single-strand annealing weakened protein 1 protein, from Baker's yeast, contains 261 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P39735", "organism_name": "Baker's yeast", "protein_name": "Single-strand annealing weakened protein 1", "length": 261, "firstPublicDate": "1995-02-01", "FUNCTION": "Catalyzes 3'-non-homologous tail removal of RAD1/RAD10-dependent single-strand annealing recombination intermediates, Plays a key role in targeting RAD1/RAD10 complex to 3'-flap cleavage substrate in recombination, Also contributes to the integrity of ribosomal DNA arrays", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAPSIATVKIARDMVLPLRIFVNRKQILQTNDKTSNKSNATIFEAPLLSNNSIICLKSPNTRIYLSQQDKKNLCDEIKEDLLLIVYELASPEIISSVLSKIRVGHSTDFQINVLPKLFAGADTDNAVTSHIQSVTRLAKFKYKLHYKHKWELDIFINSIKKIANLRHYLMFQTLTLNGFSLNAGPKTLLARKIEKQPQVPNLLIENGDADALDTPVEEDIKPVIEFMYKPVINLGEIIDVHVLHRPRRHKVRTQSKQPQEE", "length": 261, "molWeight": 29770, "crc64": "F525EF2E5347E500", "md5": "5DBFAC7182B3CBFEADF3C9EC16B3DD59"}}
{"primaryAccession": "P40239", "text": "This is CD9 antigen protein, from Cat, contains 226 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40239", "organism_name": "Cat", "protein_name": "CD9 antigen", "length": 226, "firstPublicDate": "1995-02-01", "FUNCTION": "Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity), Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity), In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity), In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (By similarity), Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity), Acts as a receptor for PSG17 (By similarity), Involved in platelet activation and aggregation (By similarity), Regulates paranodal junction formation (By similarity), Involved in cell adhesion, cell motility and tumor metastasis (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the tetraspanin (TM4SF) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAVGLWLRFDSQTKSIFEQDSQPSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIQEVQEFYKDTYNKLKSKDEPQRDTLKAIHYALDCCGLAGGVEQFISDICPQKDILSSITVKPCPEAIKEVFHNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRSREMV", "length": 226, "molWeight": 25059, "crc64": "77689D4B0C2B50B6", "md5": "468D15243FCFA2DC190ADD1079C224C0"}}
{"primaryAccession": "P40473", "text": "This is Transcriptional activator POG1 protein, from Baker's yeast, contains 351 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40473", "organism_name": "Baker's yeast", "protein_name": "Transcriptional activator POG1", "length": 351, "firstPublicDate": "1995-02-01", "FUNCTION": "Transcriptional activator which promotes cell cycle recovery with CLN2, after pheromone induced G1 arrest, probably inhibiting the ability of STE20 to activate the pheromone response pathway, Binds the promoters of genes that function in cell cycle regulation, cytoskeletal organization, and spindle assembly, May also be involved in stress-resistance", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the POG1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKQEPHRQSEEKEKPKGPMAVEREQHTSLSSGTTVTASTGDESTNSRPVESSQTEKSLSLRIRILKQLGFDDIQELNACDTGLVEQFLNVRLINDTKELEKIRESNLAKLNQIIDKCMESDKISDSTLNKILDMSMNRDTNNDNNNHLTIPSPITTKKRKINASELASPRGHRRYRSDIPTVSEVETGVGYPQIHQQPGAYTLPMPANQWMSNPYMQPPQPQVQQIMPQYLYPPGMGPQAQLPTMSSNSESQTPVMSSQFLSLNQHGLYQQNIGAHPVMSMGPQANIYGQQHQLQPGQERDQSRKSFSHRRSQSANISMANFRSPMRNPQPASSQRPVNFLIHTPKHPPPT", "length": 351, "molWeight": 39498, "crc64": "35EE3E9F93FDCE0C", "md5": "36714517794BB262FEF4FC0841826D1F"}}
{"primaryAccession": "P40474", "text": "This is Quinidine resistance protein 2 protein, from Baker's yeast, contains 542 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40474", "organism_name": "Baker's yeast", "protein_name": "Quinidine resistance protein 2", "length": 542, "firstPublicDate": "1995-02-01", "FUNCTION": "Multidrug resistance transporter involved in resistance and adaptation to quinidine and to the herbicide barban (4-chloro-2-butynyl [3-chlorophenyl] carbamate), Implicated in potassium uptake", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator superfamily, CAR1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAGATSSIIRENDFEDELAESMQSYNRETADKLALTRTESVKPEPEITAPPHSRFSRSFKTVLIAQCAFTGFFSTIAGAIYYPVLSVIERKFDIDEELVNVTVVVYFVFQGLAPTFMGGFADSLGRRPVVLVAIVIYFGACIGLACAQTYAQIIVLRCLQAAGISPVIAINSGIMGDVTTRAERGGYVGYVAGFQVLGSAFGALIGAGLSSRWGWRAIFWFLAIGSGICFLASFLILPETKRNISGNGSVTPKSYLNRAPILVLPTVRKSLHLDNPDYETLELPTQLNLLAPFKILKAYEICILMLVAGLQFAMYTTHLTALSTALSKQYHLTVAKVGLCYLPSGICTLCSIVIAGRYLNWNYRRRLKYYQNWLGKKRSKLLEEHDNDLNLVQRIIENDPKYTFNIFKARLQPAFVTLLLSSSGFCAYGWCITVKAPLAAVLCMSGFASLFSNCILTFSTTLIVDLFPTKTSTATGCLNLFRCILSAVFIAALSKMVEKMKFGGVFTFLGALTSSSSILLFILLRKGKELAFKRKKQELGVN", "length": 542, "molWeight": 59618, "crc64": "96649B74E940F63E", "md5": "844CF37B4EB931C4EB510330531E9941"}}
{"primaryAccession": "P40475", "text": "This is Quinidine resistance protein 1 protein, from Baker's yeast, contains 563 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40475", "organism_name": "Baker's yeast", "protein_name": "Quinidine resistance protein 1", "length": 563, "firstPublicDate": "1995-02-01", "FUNCTION": "Multidrug resistance transporter involved in resistance and adaptation to quinidine and ketoconazole", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator superfamily, CAR1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTKQQTSVMRNASIAKEEREGSDNNNVDRSSSDAISDNDAERSNSHSEIDNESNFDMVPYSRFSHKQKMLLVVQCAFTGFFSTVAGSIYYPVLTIIERKFNITEELANVTIVVYFIFQGVAPSIMGGLADTFGRRPIVLWAILAYFCACIGLACAHNYAQILALRCLQAAGISPVIAINSGIMGDVTTKVERGGYVGLVAGFQVVGTAFGALIGAGLSSKWGWRAIFWFLAIGSGICLVFSTLLMPETKRTLVGNGSVTPRSFLNRSLILHVGSVKKTLHLDDPDPETLEPRTSVDFLAPLKILHIREIDILLSIAGLQFSTWTTHQTALTIVLSKKYNLSVAKIGLCFLPAGISTLTSIISAGRYLNWSYRTRKVKYNRWIKEQELQLMEKYKGDKNKVAELIHSNSHYAFNLVEARLHPAFVTLLLSSIGFTAFGWCISVKTPLAAVLCTSAFASLFSNCILTFSTTLIVDLFPSKASTATGCLNLFRCLLSAIFIAALTKMVEKMRYGGVFTFLSAITSSSSLLLFYLLKNGKQLSFDRIRANDKSAGRSVGKNSEKVST", "length": 563, "molWeight": 61759, "crc64": "5FDBA6F9F7C71C72", "md5": "92CA74F81436955E78238C9E97B2AD72"}}
{"primaryAccession": "P40486", "text": "This is Protein SHQ1 protein, from Baker's yeast, contains 507 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40486", "organism_name": "Baker's yeast", "protein_name": "Protein SHQ1", "length": 507, "firstPublicDate": "1995-02-01", "FUNCTION": "Involved in the early biogenesis steps of box H/ACA snoRNP assembly", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SHQ1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MITPRFSITQDEEFIFLKIFISNIRFSAVGLEIIIQENMIIFHLSPYYLRLRFPHELIDDERSTAQYDSKDECINVKVAKLNKNEYFEDLDLPTKLLARQGDLAGADALTENTDAKKTQKPLIQEVETDGVSNNIKDDVKTIGQMGEGFNWEIEQKMDSSTNNGILKTKYGFDNLYDTVISVSTSNGNDINELDDPEHTDANDRVIERLRKENLKFDPEYYVSEYMTHKYGNEEDLEINGIKELLKFTPSIVKQYLQWYKDSTNPNLVMPIEFTDEEQKQMQDNLPKKSYLVEDIKPLYVTILSVLFSYVFEQIENEGTHTTESAWTMGKLCPQISFLDQQLKQVNELQDGMKEISKVNKDSSLIKIAIITGIRRALSYPLHRNYDLAMKAWTFVYYILRGGKRLVIRALLDIHETFRFHDVYYVYDKVLLDDLTAWFISQGSENVIRSLALEMRKEQESLSKQDIEFECIASFNEQTGEPEWETLNIREMEILAESEYREQQQNPQ", "length": 507, "molWeight": 59151, "crc64": "15A6A66C66E70C39", "md5": "871273B721ED27B66C18DCB65F537F6D"}}
{"primaryAccession": "P40858", "text": "This is Large ribosomal subunit protein bL21m protein, from Baker's yeast, contains 161 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40858", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein bL21m", "length": 161, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL21 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLQLKFIWPVARITPIYRPFTSHPFRNLATSSSISSTKAKTTKTDTTPLKLSNELYAIFKIHNRPYLVTEGDRVILPFKLKQAEVGDILNMTDVTTLGSRNYKLVGHPINTSLYTLKATVVGKTKRAFQTREVTKRRNRRVRHAKSKGDLTILRISELSMN", "length": 161, "molWeight": 18387, "crc64": "9F1EB43739BB990C", "md5": "20FBC836D7811EAB5E5526D1ECE8C4AB"}}
{"primaryAccession": "P41057", "text": "This is Small ribosomal subunit protein uS14A protein, from Baker's yeast, contains 56 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P41057", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein uS14A", "length": 56, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the universal ribosomal protein uS14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAHENVWFSHPRRYGKGSRQCRVCSSHTGLIRKYGLNICRQCFREKANDIGFNKFR", "length": 56, "molWeight": 6661, "crc64": "F1A6900EE27748C2", "md5": "A359B7A9B8799DF3C79940C132E6F216"}}
{"primaryAccession": "P41058", "text": "This is Small ribosomal subunit protein uS14B protein, from Baker's yeast, contains 56 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P41058", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein uS14B", "length": 56, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the universal ribosomal protein uS14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAHENVWFSHPRRFGKGSRQCRVCSSHTGLVRKYDLNICRQCFREKANDIGFHKYR", "length": 56, "molWeight": 6728, "crc64": "F1AAE8CCE0E62552", "md5": "C63587C5CD521F1E1498E8CED649F110"}}
{"primaryAccession": "P41698", "text": "This is Bud site selection protein 8 protein, from Baker's yeast, contains 603 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P41698", "organism_name": "Baker's yeast", "protein_name": "Bud site selection protein 8", "length": 603, "firstPublicDate": "1995-11-01", "FUNCTION": "May be involved in positioning the distal bud pole signal", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "To yeast BUD9", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MIQSDEDNLDSSETTASTSYSGTSSVSSRLQLRTSLFFENLNGAHGNPDAETEMATVAYETTSRGQGFAVYINNERFSQIMGASTSSSSSSNSSSITQFHDTQDNNIPSNTTVRPTSLRRDNEDTVPLRNVTPSQNAAVRPERAVNSPSSQRLSCALTISTSVLMGEDVEGSPIEQEHSRVVSSLYSSLANRGNDESKNGTPPRPTSIEPNETTEHSFFSYHYDDTLEPDVEEAVRLTKNKTSNVNFISSTGSKGEGETEDEVIDQYEPVNESKFIPHKLKIPEKAGSIKSSTSDDSHSPGAPGTSARKIKIPQSPSLIGNILIPSHNSDSSNESSPKDHIGHNNEEKFSSKSTRKPSTSLEEEGPPIGLPSIPVLRSVSGPSKWTKTPLRLESGNSTKSDPFSRYEGHKTPSPLTKMNKKKNKTLPEHGQPLVLAPIKSQSSESDTGQNSIIEKPARSIRRKQQEKTDNRKEDRHDAENIDLEARMPIQHIDTASIHSFDSGQNGFRDVYSIENIIVILLCCSIVPPLFFIIGCSSRRKLVSDYRLMRLLMNKEHRAALLQGFIWDVDLRWFRMFCLILGAAETVIVMAGIAIGFGVGITRE", "length": 603, "molWeight": 66289, "crc64": "83F8843CA476E6C4", "md5": "B8CA447DB13D7AB910EC75EB3A33BFB0"}}
{"primaryAccession": "P42776", "text": "This is G-box-binding factor 3 protein, from Mouse-ear cress, contains 382 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P42776", "organism_name": "Mouse-ear cress", "protein_name": "G-box-binding factor 3", "length": 382, "firstPublicDate": "1995-11-01", "FUNCTION": "Binds to the G-box motif (5'-CCACGTGG-3') of the rbcS-1A gene promoter, G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGNSSEEPKPPTKSDKPSSPPVDQTNVHVYPDWAAMQAYYGPRVAMPPYYNSAMAASGHPPPPYMWNPQHMMSPYGAPYAAVYPHGGGVYAHPGIPMGSLPQGQKDPPLTTPGTLLSIDTPTKSTGNTDNGLMKKLKEFDGLAMSLGNGNPENGADEHKRSRNSSETDGSTDGSDGNTTGADEPKLKRSREGTPTKDGKQLVQASSFHSVSPSSGDTGVKLIQGSGAILSPGVSANSNPFMSQSLAMVPPETWLQNERELKRERRKQSNRESARRSRLRKQAETEELARKVEALTAENMALRSELNQLNEKSDKLRGANATLLDKLKCSEPEKRVPANMLSRVKNSGAGDKNKNQGDNDSNSTSKLHQLLDTKPRAKAVAAG", "length": 382, "molWeight": 41114, "crc64": "48B31762CDCD977C", "md5": "0BAC200044F7AE90DDD721CE2350E43A"}}
{"primaryAccession": "P42826", "text": "This is Xylulose kinase protein, from Baker's yeast, contains 600 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P42826", "organism_name": "Baker's yeast", "protein_name": "Xylulose kinase", "length": 600, "firstPublicDate": "1995-11-01", "FUNCTION": "Xylulose kinase necessary for growth in culture media with D-xylulose as the solecarbon source", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the FGGY kinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLCSVIQRQTREVSNTMSLDSYYLGFDLSTQQLKCLAINQDLKIVHSETVEFEKDLPHYHTKKGVYIHGDTIECPVAMWLEALDLVLSKYREAKFPLNKVMAVSGSCQQHGSVYWSSQAESLLEQLNKKPEKDLLHYVSSVAFARQTAPNWQDHSTAKQCQEFEECIGGPEKMAQLTGSRAHFRFTGPQILKIAQLEPEAYEKTKTISLVSNFLTSILVGHLVELEEADACGMNLYDIRERKFSDELLHLIDSSSKDKTIRQKLMRAPMKNLIAGTICKYFIEKYGFNTNCKVSPMTGDNLATICSLPLRKNDVLVSLGTSTTVLLVTDKYHPSPNYHLFIHPTLPNHYMGMICYCNGSLARERIRDELNKERENNYEKTNDWTLFNQAVLDDSESSENELGVYFPLGEIVPSVKAINKRVIFNPKTGMIEREVAKFKDKRHDAKNIVESQALSCRVRISPLLSDSNASSQQRLNEDTIVKFDYDESPLRDYLNKRPERTFFVGGASKNDAIVKKFAQVIGATKGNFRLETPNSCALGGCYKAMWSLLYDSNKIAVPFDKFLNDNFPWHVMESISDVDNENWDRYNSKIVPLSELEKTLI", "length": 600, "molWeight": 68321, "crc64": "29A7DC28F92AA527", "md5": "61787B5C2FAFCF2E87CB1486B9A008EC"}}
{"primaryAccession": "P42900", "text": "This is Sigma-like sequence protein 1, mitochondrial protein, from Baker's yeast, contains 643 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P42900", "organism_name": "Baker's yeast", "protein_name": "Sigma-like sequence protein 1, mitochondrial", "length": 643, "firstPublicDate": "1995-11-01", "FUNCTION": "Involved in aerobic respiration where it is required for assembly of respiratory chain enzyme complexes III and IV, Also has a role in mitochondrial gene expression, May be part of a mitochondrial membrane-associated RNA-shuttling system, delivering NAM1-associated transcripts to the translation machinery", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the SLS1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MWKFNKKLARLTYRLYSSSGPSSPLHGKKKLPQNLKFVVLNPTQSGLVKNDQKQPRHRPSKKRSHKETGDNNLDFGSKLLVFEKQNSLDSALNSIRLKKPTSASLPSLEYNALLQSLTSSYNRYQLREFISTHQPDSSSHLTHWKKSKLSQYIIEKIWNCQPISTPTTPTGIKSTSLTFQFDSPREIFLLLITQNGKILTNFNKLGLTFIISIQDNELTVKGSPSLLKYAEISLNKIWSNITHENVRMYSLMPSKDVINLIQKETHTFFEYLPDLQMYKISALSTKKISMAKVFLLNAVASNPNTTQHHHTIASPALKTELYPFNNTLENLDWLNKSQDWARLQSVVPKNCTDLMTPTENATPELTDAQVSQFESSLSKNIPSLSPSDSISQSLSITLGHSLQSASFSSIFQPLIHKSFISKLLNLPMYKESSSSAVPVPVPLDQHLITNAHQSFIQLNFTPVPPTSGSSSSPFLQIWFEIDEFDNIVTTSMRPLLKLQENSVILRTPQCQTDYKITSDYIQDLLPDFDQTNPDAWLSEQKGLQEFLLKSHWKLNKYQNLMKKINISLPDNLIQQYQLTDVLTHRVLNLRFPTNTAQDDKYIIQYSDISRGFLNNGSYRQLDFINVNPSETSLKTFINDVLSF", "length": 643, "molWeight": 73257, "crc64": "6CCD6FE80D669548", "md5": "09282AC7918606EDAF51A48D0FB99CD9"}}
{"primaryAccession": "P43554", "text": "This is SWI/SNF global transcription activator complex subunit SWP82 protein, from Baker's yeast, contains 623 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P43554", "organism_name": "Baker's yeast", "protein_name": "SWI/SNF global transcription activator complex subunit SWP82", "length": 623, "firstPublicDate": "1995-11-01", "FUNCTION": "Involved in transcriptional activation, Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes, It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RSC7/SWP82 family, SWP82 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLGEDEGNTVLEKGNNPSVKQGEVGAVFIVPKILIREHERVILKQILQILDQDELVQPPLDKFPYKKLELPKYIDELKTRDATNTSYKMIQLDAYGEKKVGSNGELFGGRHYLFNTFTFTAHMGVLLVLLQDVIKVLYQSNATHDEDEFIVQHDQILVMETSEEQTKFLAKNGVIPEESKGSFKYITARSAFVEFGASVIAGGQRIVDDYWESLAKKQNLSSHQRVFKLSTNLISKISLLRPSFQNNRISNANEISANTNNTCTISTSKFESQYPIVTEQPSAEIREAYIENFAKGEHISAIVPGQSISGTLELSAQFRVPRYHSKNSFQQALQMKAMDIPIGRHEELLAQYESQAPDGSASISLPNHIPSVNPSNKPIKRMLSSILDINVSSSKNKKSEENEMIKPMNKGQHKNNTSLNINGWKFESLPLKSAENSGKQQYYRGLPLYEKNTLLERLKQLTPNEIKELEHLHDAVFVNTGLQNVRKVRTKKWKKYWQYKAGIPIGLKRSQLDEFKNKYLKDVLAQTSVTTNFNEITNTDETITTKRVPNPNFLGNCNIKDFKPPYIYSHVNKVPQNVAGDKTAVKLDTEVKNTNANPVVATDPVAAKPDNLANFSNEVAMNN", "length": 623, "molWeight": 70276, "crc64": "A8AC00CAC8F0ED0E", "md5": "1FC35CC023DFCE2B058A56BDD36A0056"}}
{"primaryAccession": "P43596", "text": "This is ISWI one complex protein 3 protein, from Baker's yeast, contains 787 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P43596", "organism_name": "Baker's yeast", "protein_name": "ISWI one complex protein 3", "length": 787, "firstPublicDate": "1995-11-01", "FUNCTION": "Functions as component of the ISW1A complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA, The ISW1A complex represses gene expression at initiation through specific positioning of a promoter proximal dinucleosome", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDSPSNSIQNLQQEAQGSSSAQLADHDHDRVSMAMPLQTDQSVSVSQSSDNLRRSRRVPKPRTSIYDEYEEELKERANKPKRKRPAPPKKKAPSTQNSKSNDKVEKKKTTSIAKDGKPTLKTNDKKVAPKPKPAHEQVEPALIPSNWTSVIPLLTSDFKNQYSVISRLKNPNMKPVPYAGDIIKLMAFINKFSSFFHSDLQNLSFQDFEVGLDLYPGDPNGSAAGIVKGPEDTSLLLYPDFMAIKDIVYCQDKMNLLFLSLLDLTFTENFDGKSAKKKGPLTTWENLKSSSKKVFSNPLYRLRLVAREWGYPREWRQQLPSDQDISKPKTALFEQDEQTPVVDPSHPEILTPNIYTWNANEPLPLESNPLYNREMDKNGILALKPMDRVVLLRALTDWCASHSSAIHDEIYKLTHGKKDPVFGIQTQQVPRYTIEGVDNTINQFKKLCSLIQSRYEIRSKKKHFVKQLKEGKKPDLSRKLEILKEIKAELKNAVKSEKDELLFSLYDKWVPLFEGELPDQPLANPFSERLYKLRLQEFFLGRVPHIGDFYMPRLHSYGDSLEMSTFTDLRNLQALLSKFKNNEYNAFTLFENDGQSMSAQFKLFYHDTPSLAHDVARGRNTSGKVYWYELCHDSATLLEFLEFLDYKIVKPQDEKKEGNEKEKEALNNEAHILEQKSTTDNNPSINTNPLPKDAKYNTARKKLQILKEFLSDYYFILRQFEQMKVQFADMKPGKRQLRRIQRQTVNYNTEYDSEEYVDDEEDDEADIYDDNDNDSSFDDGRVKRQRT", "length": 787, "molWeight": 90897, "crc64": "1919A8A1F58B5340", "md5": "A3B6382AD3A4467F51ECC39EFDF6B172"}}
{"primaryAccession": "P46784", "text": "This is Small ribosomal subunit protein eS10B protein, from Baker's yeast, contains 105 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P46784", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein eS10B", "length": 105, "firstPublicDate": "1995-11-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102), eS10 plays a role as a positive regulator of the GCN2 kinase activity by stimulating GCN1-mediated GCN2 activation (PubMed:25437641)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS10 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLMPKQERNKIHQYLFQEGVVVAKKDFNQAKHEEIDTKNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPGTYIQERNPSQRPQRRY", "length": 105, "molWeight": 12738, "crc64": "BE50B625869963CF", "md5": "F3EDFD15C64877A08C3577D9F9C09517"}}
{"primaryAccession": "P47040", "text": "This is Protein BTN1 protein, from Baker's yeast, contains 408 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P47040", "organism_name": "Baker's yeast", "protein_name": "Protein BTN1", "length": 408, "firstPublicDate": "1996-02-01", "FUNCTION": "Plays a role in vacuolar arginine transport, Involved in pH homeostasis, May be involved in ion homeostasis together with IST2, Not necessary for mitochondrial function or ATP synthase degradation", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the battenin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSDKSHQIYCYFWLFGLINNVLYVVILSAAVDIVGPTLPKSLVLLADIFPSLAIKLCSPFFIDRIKYSYRIWSLITMSCLGMFLVSFKNLFVCLLGISFASISSGFGEVTFLQLTHYYKQISLNGWSSGTGGAGIIGGASYMFLTSIFKVPVKLTLLVFSLLPFAFLFYFKLESNDTNLTYQSLQQIDEAEDDQLVPFPVAFTHTNASQSLYSTRQHILQTVKRLRRLVFPYMVPLTTVYLFEYLINQAVAPTLLFPINGDERSKSMPFFFHKYRDIYVTYGTLYQLGVFISRSFGHLMRMRSLYILAFLQGVNLCITVLQSWFYVTHSPWAVMILIFYEGFLGGASYVNTFLNILEQEDPDETEFAMGAVSIADSFGVFLAALLGLGLEPKLCRHQIADDRPWCRME", "length": 408, "molWeight": 46383, "crc64": "BAB6891F676E80EE", "md5": "C9B09F3446847144D69AE24FC57E13B4"}}
{"primaryAccession": "P47095", "text": "This is Methylthioribulose-1-phosphate dehydratase protein, from Baker's yeast, contains 244 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P47095", "organism_name": "Baker's yeast", "protein_name": "Methylthioribulose-1-phosphate dehydratase", "length": 244, "firstPublicDate": "1996-02-01", "FUNCTION": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the aldolase class II family, MtnB subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSQDVLIHSDDPCHPANLICTLCKQFFHNNWCTGTGGGISIKDPNTNYYYLAPSGVQKEKMIPEDLFVMDAQTLEYLRSPKLYKPSACTPLFLACYQKKNAGAIIHTHSQNAVICSLLFGDEFRIANIEQIKAIPSGKVDPVTKKPMALSFFDTLKIPIIENMAHEDELIDDLHKTFKDYPDTCAVIVRRHGIFVWGPTIDKAKIFNEAIDYLMELAIKMYQMGIPPDCGIGEEKKHLKMASP", "length": 244, "molWeight": 27427, "crc64": "C41FAD142D677A00", "md5": "5ACB9006E01B0EEB61546E5EC84C167C"}}
{"primaryAccession": "P47150", "text": "This is Small ribosomal subunit protein uS7m protein, from Baker's yeast, contains 247 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P47150", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein uS7m", "length": 247, "firstPublicDate": "1996-02-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uS7 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLHCARRYMLVRPRLLWQSGTCVARFQSSVRTPASEPSAEKGVDEWLEAINELREEFSAKEYLPETSLAPPGQSKVDLLQGSQAGSKIKPTAEQLAQWEALKSVPIPPRKNATLDHITNMIMRHGKKEKAQTILSRALYLVYCQTRQDPIQALEKSLDELAPLMMTKTFNTGVAKASVIPVPLNKRQRNRIAWNWIVQSANQRVSSDFAVRLGEELTAIAKGTSSAFEKRDQIHKTAIAHRAYIQLK", "length": 247, "molWeight": 27816, "crc64": "007C8A1ACF8D9C2B", "md5": "98CE5CB8B5CE2C4042C1938EABAA5F22"}}
{"primaryAccession": "P48234", "text": "This is Ribosome biogenesis protein ENP2 protein, from Baker's yeast, contains 707 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P48234", "organism_name": "Baker's yeast", "protein_name": "Ribosome biogenesis protein ENP2", "length": 707, "firstPublicDate": "1996-02-01", "FUNCTION": "May be involved in rRNA-processing and ribosome biosynthesis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WD repeat NOL10/ENP2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVLKSTSANDVSVYQVSGTNVSRSLPDWIAKKRKRQLKNDLEYQNRVELIQDFEFSEASNKIKVSRDGQYCMATGTYKPQIHVYDFANLSLKFDRHTDAENVDFTILSDDWTKSVHLQNDRSIQFQNKGGLHYTTRIPKFGRSLVYNKVNCDLYVGASGNELYRLNLEKGRFLNPFKLDTEGVNHVSINEVNGLLAAGTETNVVEFWDPRSRSRVSKLYLENNIDNRPFQVTTTSFRNDGLTFACGTSNGYSYIYDLRTSEPSIIKDQGYGFDIKKIIWLDNVGTENKIVTCDKRIAKIWDRLDGKAYASMEPSVDINDIEHVPGTGMFFTANESIPMHTYYIPSLGPSPRWCSFLDSITEELEEKPSDTVYSNYRFITRDDVKKLNLTHLVGSRVLRAYMHGFFINTELYDKVSLIANPDAYKDEREREIRRRIEKERESRIRSSGAVQKPKIKVNKTLVDKLSQKRGDKVAGKVLTDDRFKEMFEDEEFQVDEDDYDFKQLNPVKSIKETEEGAAKRIRALTAAEESDEERIAMKDGRGHYDYEDEESDEEESDDETNQKSNKEELSEKDLRKMEKQKALIERRKKEKEQSERFMNEMKAGTSTSTQRDESAHVTFGEQVGELLEVENGKKSNESILRRNQRGEAELTFIPQRKSKKDGNYKSRRHDNSSDEEGIDENGNKKDNGRSKPRFENRRRASKNAFRGM", "length": 707, "molWeight": 81734, "crc64": "6C3DFB372C058A04", "md5": "6F47EE45BA028062627C2575A5F5A011"}}
{"primaryAccession": "P48239", "text": "This is Glutathione S-transferase omega-like 1 protein, from Baker's yeast, contains 356 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P48239", "organism_name": "Baker's yeast", "protein_name": "Glutathione S-transferase omega-like 1", "length": 356, "firstPublicDate": "1996-02-01", "FUNCTION": "Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the GST superfamily, Omega family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVSYKGTISKTHSVFKPEKGRYYIYGALGCPFTHRAILARSLKKLEPVLGLVLSHWQLDSKGARFLPAPHRPEKYKERFFTATGGIASAKLDESEELGDVNNDSARLFVDGAFDPVENISRLSELYYLNDPKYPGTKFTVPVLWDSKTRKIVNNESGDIIRILNSGVFDEFIQSEETNVIDLVPHDLIDEIDKNIKWVHPKINLGVYKVGLAENGKIYETEVKTLFENLQKMECVLKENYKRLEEQFSGNKQKILAKYFVLGQRLTEADIRLYPSIIRFDVVYVQHFKCNLKTIRDGFPYLHLWLINLYWNYAEFRFTTDFNHIKLFYIRMEVSRNKINQFGIVPLGPKPDISRL", "length": 356, "molWeight": 41301, "crc64": "B4639BD195CDF7F5", "md5": "FE5B16181D0570321DAA51CE3074A781"}}
{"primaryAccession": "P48527", "text": "This is Tyrosine--tRNA ligase, mitochondrial protein, from Baker's yeast, contains 492 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P48527", "organism_name": "Baker's yeast", "protein_name": "Tyrosine--tRNA ligase, mitochondrial", "length": 492, "firstPublicDate": "1996-02-01", "FUNCTION": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the class-I aminoacyl-tRNA synthetase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLELRSCSNLVNSSRRLVPLVTYSGLSAITLPKSRFYSQPSALEVQGTSDSRSDNILDELKQRGLVSQVSQPESFLRTKLNGNDKIKLYCGVDPTAQSLHLGNLVPLMVLLHFYVKGHDIVTVIGGATGKVGDPSGRKTERDVMENDIRQSNVASISQQLQRFFKNGLEYYRNRCALTEDVPSGKYTPRNNFNWWKDIKMLDFLADFGRHIRVQSMLARDSISSRLQTKNGLGFNEFTYQVLQAYDFYHLYKEENVTIQVGGNDQWGNITAGIDLINRIQPIKNKGLPFGITVPLLTTATGEKFGKSAGNAVFIDPSINTAYDVYQFFYNTLDADVPKFLKIFTFLNSSEIKKIVETHIKSPSLRYGQTLLAKEVTDMLYGVGSGSDSEALSNIIFGRYDGTLSAAKLVDLCKKARILQYADREIDLIKLICKLVNCSVSEARRKLSQGSVYLHHSKSKVNENISNLAPFLIDDRVLILRIGKQKCFIIEMR", "length": 492, "molWeight": 55287, "crc64": "2159116E1CB5ED2E", "md5": "E2DFE5CCBB14BEB6C08E92F0B235BFCE"}}
{"primaryAccession": "P49047", "text": "This is Vacuolar-processing enzyme alpha-isozyme protein, from Mouse-ear cress, contains 478 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P49047", "organism_name": "Mouse-ear cress", "protein_name": "Vacuolar-processing enzyme alpha-isozyme", "length": 478, "firstPublicDate": "1996-02-01", "FUNCTION": "Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms (PubMed:7579169), Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds (PubMed:14688293)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the peptidase C13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTTVVSFLALFLFLVAAVSGDVIKLPSLASKFFRPTENDDDSTKWAVLVAGSSGYWNYRHQADVCHAYQLLKKGGVKEENIVVFMYDDIAKNEENPRPGVIINSPNGEDVYNGVPKDYTGDEVNVDNLLAVILGNKTALKGGSGKVVDSGPNDHIFIYYSDHGGPGVLGMPTSPNLYANDLNDVLKKKYASGTYKSLVFYLEACESGSIFEGLLPEGLNIYATTASNAEESSWGTYCPGEDPSPPSEYETCLGDLYSVAWIEDSEKHNLQTETLHEQYELVKKRTAGSGKSYGSHVMEFGDIGLSKEKLVLFMGTNPADENFTFVNENSIRPPSRVTNQRDADLVHFWHKYQKAPEGSARKVEAQKQVLEAMSHRLHVDNSILLIGILLFGLEGHAVLNKVRPSGEPLVDDWDCLKSLVRAFERHCGSLSQYGIKHMRSIANMCNAGIQMRQMEEAAMQACPTIPTSPWSSLDRGFSA", "length": 478, "molWeight": 52670, "crc64": "D73D1F353E2FE898", "md5": "2DA26580EB8420BF8F493DBD7693E4FC"}}
{"primaryAccession": "P49406", "text": "This is Large ribosomal subunit protein bL19m protein, from Human, contains 292 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P49406", "organism_name": "Human", "protein_name": "Large ribosomal subunit protein bL19m", "length": 292, "firstPublicDate": "1996-02-01", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL19 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAACIAAGHWAAMGLGRSFQAARTLLPPPASIACRVHAGPVRQQSTGPSEPGAFQPPPKPVIVDKHRPVEPERRFLSPEFIPRRGRTDPLKFQIERKDMLERRKVLHIPEFYVGSILRVTTADPYASGKISQFLGICIQRSGRGLGATFILRNVIEGQGVEICFELYNPRVQEIQVVKLEKRLDDSLLYLRDALPEYSTFDVNMKPVVQEPNQKVPVNELKVKMKPKPWSKRWERPNFNIKGIRFDLCLTEQQMKEAQKWNQPWLEFDMMREYDTSKIEAAIWKEIEASKRS", "length": 292, "molWeight": 33535, "crc64": "4056F39694284A9F", "md5": "EA0260BCA597E0D893809319349A86C9"}}
{"primaryAccession": "P50944", "text": "This is Vacuolar amino acid transporter 4 protein, from Baker's yeast, contains 713 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P50944", "organism_name": "Baker's yeast", "protein_name": "Vacuolar amino acid transporter 4", "length": 713, "firstPublicDate": "1996-10-01", "FUNCTION": "Involved in amino acid efflux from the vacuole to the cytoplasm, Capable of transporting large neutral amino acids including tyrosine, glutamine, asparagine, isoleucine and leucine", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the amino acid/polyamine transporter 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVTNNGDGEHLGIRRNGNLRHPSNNMKIPRRAQSTVLNSNPFYSRKYSMSTLTPRDICRSVDSRVFVDMSSPNFQTLEDPHRDEIINSVRLNYLNSSKRSSVSHGNEAIPRVNPTKNSSASTIAAANVDSDDDETNLSSAGGDITHDIYKLVKAEDPKRLRRPRSMENVTPKIEHHTKLSSASGLNVPGGFRREFIVNKKRQEHQLNDSASSDFTSHESDSINQSSPSSNQDIDKVPFLTRNFLEFLYVFGHFAGESFEDDFIPDSSNMMIRGEDERSALLSRPDHMKVLPSAKGTTSTKKVFLILLKSFIGTGVLFLPNAFHNGGLFFSVSMLAFFGIYSYWCYYILVQAKSSCGVSSFGDIGLKLYGPWMRIIILFSLVITQVGFSGAYMIFTAKNLQAFLDNVFHVGVLPLSYLMVFQTIIFIPLSFIRNISKLSLPSLLANFFIMAGLVIVIIFTAKRLFFDLMGTPAMGVVYGLNADRWTLFIGTAIFAFEGIGLIIPVQDSMRNPEKFPLVLALVILTATILFISIATLGYLAYGSNVQTVILLNLPQSNIFVNLIQLFYSIAIMLSTPLQLFPAIKIIENKFFPKFTKIYVKHDDLTTRVELRPNSGKLNWKIKWLKNFIRSIIVIIVVSIAYFGSDNLDKFVSVIGSLACIPLVYIYPSMLHLRGNSLPETKGEFWRFKPMLDTILIFFGIASMLYTSYQSIFGV", "length": 713, "molWeight": 80026, "crc64": "EAB458A2FEB660FB", "md5": "AB9602C4812F54CA546F9B4CCAED4DF9"}}
{"primaryAccession": "P53070", "text": "This is Mitochondrial translation optimization protein 1 protein, from Baker's yeast, contains 669 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53070", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial translation optimization protein 1", "length": 669, "firstPublicDate": "1996-10-01", "FUNCTION": "Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MnmG family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRVTTLASSCTSFPLQVLRRRLTISSLTSFQPTTKTQVVVIGAGHAGCEAAAASSRTGAHTTLITPSLTDIGKCSCNPSIGGVGKGILVKEIDALDGLMGKVTDLAGVQFKMLNRSKGPAVWGPRAQIDRELYKKYMQRELSDKKAHPNLSLLQNKVADLILYDPGCGHKVIKGVVLDDGTQVGADQVIITTGTFLSAEIHIGDKRIAAGRIGEQPTYGISNTLQNEVGFQLGRLKTGTPARLAKESIDFSALEVQKGDALPVPMSFLNETVSVEPTKQLDCFGTHTTPQMHDFLRNNLHQSIHIQDTTIKGPRYCPSIEAKILRFPDRSSHKIWLEPEGFNSDVIYPNGISNSMPEDVQLQMMRLIPGMANVEILQPAYGVEYDYVDPRQLKPSLETKLVDGLFLAGQINGTTGYEEAAAQGIIAGINAGLLSRQEREQLVLKRSEAYIGVLIDDLINNGVIEPYRMFTSRSEFRISVRADNADFRLTPIGAQLGIISPVRLSQYSRDKHLYDETIRALQNFKLSSQKWSSLLQANIAPQAENRSAWEIFRFKDMDLHKLYECIPDLPINLLDIPMHVVTKINIQGKYEPYIVKQNQFVKAFQADENMLLPQDYDYRQLPTLSTECKLLLNRVQPLTIGQARRIQGITAAALFELYRVARKPSQPVM", "length": 669, "molWeight": 74215, "crc64": "917F22AE324F1B87", "md5": "347E3C0432A3C35CBE629BEAC6B2C324"}}
{"primaryAccession": "P53075", "text": "This is Outer spore wall assembly protein SHE10 protein, from Baker's yeast, contains 577 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53075", "organism_name": "Baker's yeast", "protein_name": "Outer spore wall assembly protein SHE10", "length": 577, "firstPublicDate": "1996-10-01", "FUNCTION": "Involved in spore wall assembly (PubMed:23966878), May be a component of the mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease involved in the cleaving RNA transcripts to generate primers for DNA replication in mitochondria (PubMed:20086051), Causes growth arrest when highly overexpressed (PubMed:7762298)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the OSW/SHE family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGKLIKLITTLTVLVSLLQYCCEFNSGSISCERTQTLCHYTNPRVWNTYFSRNCELYKNKVSPGFDIVARKYDTAVKPVIDDATVKVNKVAIQPAFKVIHSQCKKWNCGKYYQLVRSPMVKTRRFFFAKYNAFVKPNLDKFFTAEFRSHLKERILKYKNIGHYYFTITSRCIKSKYDFIVGNTEEKLMGKFKNKDTHGIHGSVTREPSSEDMVLTVSTMESDEEELTTTSTQTVVETITLDQEEASAVANHAHDDEASTDVEGSTDVNVNEQALLQEDFDMWSETILQKTQDVIQLFEKDVSKYINGKLVEEANHFKAKFQSLDDKSKKFFSKISLAINDIECVEGIDSETGKKIFFDKSGSTEISQYITRELVREYFNETRSTLDELTNAMEKDLSEITDEIEKKVNAIREENVEVFEEWGDIIVNEWSKRMAYVDVINAHMGADDDTTLDEEKAKSSVNWKKFLKGKKQIIESRDKLAHHSADLSRVNAFRQKVQKKILSFTQESGEFLYILRSKANLQFQERERKERERKEREKAAAEEFQRQQELLRQQEEEDEEDVSYTSTSTITTTITMTL", "length": 577, "molWeight": 66862, "crc64": "EF4CA95FA3157660", "md5": "96A5704932DFB99D6FCA72EB71A53155"}}
{"primaryAccession": "P53102", "text": "This is Meiotic nuclear division protein 1 protein, from Baker's yeast, contains 219 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53102", "organism_name": "Baker's yeast", "protein_name": "Meiotic nuclear division protein 1", "length": 219, "firstPublicDate": "1996-10-01", "FUNCTION": "Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis, Stimulates DMC1-dependent homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the MND1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGPKRQTVSLQEKKNRILNFFQETYTFYNIKELEKSIPKKCGISPMIVKDLVQQMIDEDGVISVEKCGNINIYWCFKNQTLQKLYDSSELIKKKIQEVKCDIATYKQELDKTLATGRRKKFTVGQKSYNREALLEKRKKIQDEIKKKSNSLQKIESIRWDAAKIQENKQQIRLKKVHLEKTTDNIEILIDYLYKKFFLKPEQIRKEFGIPEEFKEFTEV", "length": 219, "molWeight": 26083, "crc64": "C81729B2AC8018E0", "md5": "5B96608A3E0766AB1E439FF93780B279"}}
{"primaryAccession": "P53136", "text": "This is Ribosome biogenesis protein NSA1 protein, from Baker's yeast, contains 463 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53136", "organism_name": "Baker's yeast", "protein_name": "Ribosome biogenesis protein NSA1", "length": 463, "firstPublicDate": "1996-10-01", "FUNCTION": "Involved in the biogenesis of the 60S ribosomal subunit", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the NSA1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRLLVSCVDSGSIKEVLCNIGTDTSVQSALQPFHVAPHLAEGLKAYVDRMWVISEDEAILARNSGVVELVKISKHLKENEALQVDPKGESKNEKSLSDDLPKFDISEFEITSSVSDLFDDAKLESLSSKSVKRTKLVDGFVTLCPIKKDSSNNTFVAATKSGLLHIIKKGEDKKLIKLASLGLKAPVEFLQLYDLEDTDTDKYIFAYGGEENLIKLVEIDSSFQSLKQIWEAKNVKNDRLDMRVPVWPMALRFLEPSPGKTEKGKLNYQFAAITRWSHLTKYSTQHGRKPFAQIDLLPNREPLSQMEVFDAKGENVVSSLGNFQSETFNELNVITTDYKKNVFKFDGNGRMLGKVGRDDITGSSTYIHVHDGKYLLQGGLDRYVRIFDIKTNKMLVKVYVGSRINFIVMLDDVEIEMPLSPSAKAAKGKQKRKVTELEEDADELWNKLEGKVAASKASKKSKI", "length": 463, "molWeight": 51907, "crc64": "4BF4BECDBB689F1A", "md5": "EF9D646473E236A2D4C5092846999606"}}
{"primaryAccession": "P53174", "text": "This is Pheromone-regulated membrane protein 8 protein, from Baker's yeast, contains 237 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53174", "organism_name": "Baker's yeast", "protein_name": "Pheromone-regulated membrane protein 8", "length": 237, "firstPublicDate": "1996-10-01", "FUNCTION": "May be involved in endoplasmic reticulum exit trafficking of proteins", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DUP/COS family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQTPSENTNAKSDSLDEPGAYLIEENVALPKDIFHSYLSYWIYEAAHCTPVMLLSLVIGVLISIIILFHDNENCVGVSVGFLLIFSGILVIVLILRFGPQISDEDFKCKLLMEIITRKPTVKGKEWRTITYKMNQYLFDNDLWNTPYYFYRDEDCHRYFLSLIKGRTFKKQKESSASNVKDAQSNDETAGTPNEAAESSSFSAGPNFIKLLTKAAEIEQQFQKEYWRQEYPGVDEFF", "length": 237, "molWeight": 27250, "crc64": "565C4A3B5067269A", "md5": "1D4C3A4FBA570D90F5D5955A05E25DD8"}}
{"primaryAccession": "P53220", "text": "This is Mitochondrial import inner membrane translocase subunit TIM21 protein, from Baker's yeast, contains 239 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53220", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM21", "length": 239, "firstPublicDate": "1996-10-01", "FUNCTION": "Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane, Required to keep the TOM and the TIM23 complexes in close contact, At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix, In the complex, it acts as an antagonist of TIM50 by reducing preprotein accumulation at the TOM23 complex and promotes dissociation of the PAM complex from the TIM23 complex", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the TIM21 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSSLPRSLLRLGHRKPLFPRYNTFVNSSVITHTSLLRTRLYSNGTGATSGKKDDKTRNKPKPLWPQVKSASTFTFSGILVIGAVGISAIVIYLILSELFSPSGDTQLFNRAVSMVEKNKDIRSLLQCDDGITGKERLKAYGELITNDKWTRNRPIVSTKKLDKEGRTHHYMRFHVESKKKIALVHLEAKESKQNYQPDFINMYVDVPGEKRYYLIKPKLHPVSNSKGFLGIRWGPRKD", "length": 239, "molWeight": 27206, "crc64": "FC140F3034E5B5BB", "md5": "C6567A87D0D3120D2234E070BB9F7AD6"}}
{"primaryAccession": "P53258", "text": "This is GTPase-activating protein GYP2 protein, from Baker's yeast, contains 950 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53258", "organism_name": "Baker's yeast", "protein_name": "GTPase-activating protein GYP2", "length": 950, "firstPublicDate": "1996-10-01", "FUNCTION": "Stimulates specifically the GTPase activity of SEC4, YPT6 and YPT36, Inactivates YPT6 during recycling between the endosome and the Golgi compartments", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSFFDSLRQKAPFLDKLADSFTPTLTRDEKFRLKYKLPANENILEDTNAEVSFATSIKDGKGHSDRVNNKGRKTAYVYSGRLFLTPHFLVFRDAFDHSSCVLILNISTIKRVERSPSESYEFALLVTLYTGAKVLIQFIGIRYRSEQFCDKLKLNLKENIPNAKTLPAFLETSYSEFLIAKNILGKKDITVPRAGLGQHFKYPGNPTMVKEKAKLRLWFDYFRENGRNLAVVQTPMFRKLIRIGVPNRMRGEIWELCSGAMYMRYANSGEYERILNENAGKTSQAIDEIEKDLKRSLPEYSAYQTEEGIQRLRNVLTAYSWKNPDVGYCQAMNIVVAGFLIFMSEEQAFWCLCNLCDIYVPGYYSKTMYGTLLDQRVFESFVEDRMPVLWEYILQHDIQLSVVSLPWFLSLFFTSMPLEYAVRIMDIFFMNGSITLFQVALAVLKINADDILQADDDGMFIAIIKHYFQTLGQSAHPDSSDIKYRQITKFQELLVTAFKEFSVISEEMAMHARHKYEKGIFQNIETFMKRTQLRHMPKTFNLSSDDLSNIYDMFYQSIETYKISMGTGSSNMGFEVFIQFLSKFCDSCRPCEKDKDPAFRKQKRNFLQRLFDNWDSAHIGELTLNDVVTGLDKLVTVDLLQAINYFFSLYDTDGDGELHREEVLQLSEGLLLLTEPWKSGRYVDLLTKKRIEDDIAENIIKESGGEIATMNQIELPTGVTIDEEKYKVEQAERYLKAASNFLQRSFEYAKAVDLAEEVNLIDLSDDEGEEKRTVKQKQLESIKANAALDPTHPKVIDLPTFRMIILADETYELFFSNTLRSSVHVDEHVNIDNKNKVLRSMFDGILADGKRVAEQVRRRVDSVATRSSIASVESTPTAAASSITTKEEKYDDLDDFTSEHQPENEELLQSSWFEIDDANETSTKAIQERSFEPLSANSSEEKSNLIEFEA", "length": 950, "molWeight": 109259, "crc64": "888BC930C1358657", "md5": "601998948042B914367ADE3648A86BE5"}}
{"primaryAccession": "P53266", "text": "This is Cytochrome oxidase assembly protein SHY1 protein, from Baker's yeast, contains 389 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53266", "organism_name": "Baker's yeast", "protein_name": "Cytochrome oxidase assembly protein SHY1", "length": 389, "firstPublicDate": "1996-10-01", "FUNCTION": "Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane, Involved in a step that couples MSS51-COX14-dependent regulation of COX1 translation to early steps of cytochrome c oxidase assembly", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the SURF1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSLLGARSTYRWFSIAASIPTKNAIGKSTYLLASRNQQYRGIITSTVDWKPIKTGKSPNDDSRRERSFGKKIVLGLMFAMPIISFYLGTWQVRRLKWKTKLIAACETKLTYEPIPLPKSFTPDMCEDWEYRKVILTGHFLHNEEMFVGPRKKNGEKGYFLFTPFIRDDTGEKVLIERGWISEEKVAPDSRNLHHLSLPQEEHLKVVCLVRPPKKRGSLQWAKKDPNSRLWQVPDIYDMARSSGCTPIQFQALYDMKDHPIIEEHTRNEASQNNSTSSLWKFWKREPTTAVNGTQAVDNNTSKPRSRQEMPTDQTIEFDERQFIKAGVPIGRKPTIDLKNNHLQYLVTWYGLSFLSTIFLIVALRKAKRGGVVSQDQLMKEKLKHSRKYM", "length": 389, "molWeight": 45056, "crc64": "2C95E607B7507321", "md5": "1131A456277A2C5F91830D0579B7D7FD"}}
{"primaryAccession": "P53437", "text": "This is RNA polymerase I-specific transcription initiation factor RRN9 protein, from Baker's yeast, contains 365 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53437", "organism_name": "Baker's yeast", "protein_name": "RNA polymerase I-specific transcription initiation factor RRN9", "length": 365, "firstPublicDate": "1996-10-01", "FUNCTION": "Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex, Together with SPT15/TBP UAF seems to stimulate basal transcription to a fully activated level", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RRN9 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSDLDEESQIETQIDAPIEDIIRGSELTTTTADKETLKSANELLDSLEHSHRVDLSLHLYSAYLLKRLLYKANEKKHFYEVNQFVKTQIKDNWTSWPNPNTIIDPSVDKLYEDIPEGIANVSVQPGEISNRALMHASDMMRVELDAQWQKFLSKSALDHDVTLDVDELNIPNEISRNILVKLDSLFEGLHDKIAKENEFDVRQDKHSNNIRANQIDDEPMQANRRIKYTYHDLVSRGCEMNEDMTDIYMKSLELYNDIPEKYKKRKFRLPKQILKKYHQPKKTSSYLKELLSKTREDFIPVEKLLKDKRLTSKDKSKLQRLNREETEDALNKRTFFQVKGYLEDENEISDYELDDCLIELPNGNI", "length": 365, "molWeight": 42813, "crc64": "4C1E261C6FCAF850", "md5": "31155D5564BE775B8564B02E3FFB5014"}}
{"primaryAccession": "P56271", "text": "This is Acid alpha-amylase protein, from Aspergillus niger, contains 484 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P56271", "organism_name": "Aspergillus niger", "protein_name": "Acid alpha-amylase", "length": 484, "firstPublicDate": "1998-07-15", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 13 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "LSAASWRTQSIYFLLTDRFGRTDNSTTATCNTGNEIYCGGSWQGIIDHLDYIEGMGFTAIWISPITEQLPQDTADGEAYHGYWQQKIYDVNSNFGTADNLKSLSDALHARGMYLMVDVVPDHMGYAGNGNDVDYSVFDPFDSSSYFHPYCLITDWDNLTMVEDCWEGDTIVSLPDLDTTETAVRTIWYDWVADLVSNYSVDGLRIDSVLEVQPDFFPGYNKASGVYCVGEIDNGNPASDCPYQKVLDGVLNYPIYWQLLYAFESSSGSISNLYNMIKSVASDCSDPTLLGNFIENHDNPRFAKYTSDYSQAKNVLSYIFLSDGIPIVYAGEEQHYAGGKVPYNREATWLSGYDTSAELYTWIATTNAIRKLAIAADSAYITYANDAFYTDSNTIAMAKGTSGSQVITVLSNKGSSGSSYTLTLSGSGYTSGTKLIEAYTCTSVTVDSSGDIPVPMASGLPRVLLPASVVDSSSLCGGSGRLYVE", "length": 484, "molWeight": 52935, "crc64": "04D596E34680656D", "md5": "273BCA92BDCBA8CEC104FDC37A8B6A89"}}
{"primaryAccession": "P59936", "text": "This is Potassium channel toxin alpha-KTx 12.1 protein, from Brazilian scorpion, contains 62 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P59936", "organism_name": "Brazilian scorpion", "protein_name": "Potassium channel toxin alpha-KTx 12.1", "length": 62, "firstPublicDate": "2003-10-31", "FUNCTION": "Potently blocks Kv1,3/KCNA3, Kv1,2/KCNA2, and Shaker potassium channels (PubMed:24590385) and inhibits high conductance calcium-activated potassium channels (PubMed:10082164), Is potent against Kv1,3/KCNN3 (IC(50)=0,55 nM) and Kv1,2/KCNN2 (IC(50)=6,19 nM) (PubMed:24590385), It also stimulates the release of NO, IL-6 and TNF-alpha in J774,1 cells and presents a pro-inflammatory activity in mice (PubMed:21549737, PubMed:23085190)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 12 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQVFYGLLLMFILCSTIHLSEQWCSTCLDLACGASRECYDPCFKAFGRAHGKCMNNKCRCYT", "length": 62, "molWeight": 7083, "crc64": "73A73207EE885334", "md5": "29C2B80E42AAE68A3913E087C68BC0F5"}}
{"primaryAccession": "P81661", "text": "This is Thrombin-like enzyme bothrombin protein, from Jararaca, contains 232 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P81661", "organism_name": "Jararaca", "protein_name": "Thrombin-like enzyme bothrombin", "length": 232, "firstPublicDate": "2001-06-01", "FUNCTION": "Thrombin-like snake venom serine protease that clots fibrinogen by releasing fibrinopeptide A from the alpha chain of fibrinogen (FGA), induces platelet aggregation through its interaction with GPIb (GP1BA/GP1BB), and activates factor VIII (F8)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Snake venom subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "VIGGDECDINEHPFLAFMYYSPQYFCGMTLINQEWVLTAAHCDKTYMRIYLGIHTRSVANDDEVIRYPKEKFICPNKKKNVITDKDIMLIRLNRPVKNSTHIAPISLPSNPPSVGSVCRIMGWGAITTSEDTYPDVPHCANINLFNNTVCREAYNGLPAKTLCAGVLQGGIDTCGGDSGGPLICNGQFQGILSWGSDPCAEPRKPAFYTKVFDYLPWIQSIIAGNKTATCPP", "length": 232, "molWeight": 25584, "crc64": "BFCD46A729D3E8AA", "md5": "ED8797403FAEE0DD655C7ACF5777C61F"}}
{"primaryAccession": "P82413", "text": "This is Large ribosomal subunit protein bL19c protein, from Spinach, contains 233 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P82413", "organism_name": "Spinach", "protein_name": "Large ribosomal subunit protein bL19c", "length": 233, "firstPublicDate": "2006-09-05", "FUNCTION": "Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL19 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASKVLPQALLVIPSNHSLQCPPLKKQLGFPIDSNRRFSLSSNCRSNLMVSRASSNLFSSNFSSIFSFPARNSFVVRSEAEDSSDAPAESVAVVAEEELPVESEAEAEERPPRQQRVKLGDIMGILNKKAVHAAEELRPVPGIRTGDIVQIRLEVPENKRRLSVYKGIVISRQNAGIHTTIRIRRIIAGVGVEIVFPLYSPNIKEIKVVSHRKVRKARLYYLRDKLPRLSTFK", "length": 233, "molWeight": 26080, "crc64": "62CC200F4019E392", "md5": "5D897628F39EC477A39E20F33A0D8F83"}}
{"primaryAccession": "P82715", "text": "This is PsbP domain-containing protein 5, chloroplastic protein, from Mouse-ear cress, contains 297 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P82715", "organism_name": "Mouse-ear cress", "protein_name": "PsbP domain-containing protein 5, chloroplastic", "length": 297, "firstPublicDate": "2007-11-13", "FUNCTION": "Involved in strigolactone biosynthesis", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the psbP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MALLCPSLPSPNSRLFRCRSSNISSKYHGASKELMIARSGVSTRSISSEKGLSRRDLVLIGLSSPLSMFLPLSSPVTHAEEDVKMSGEELKMGTMVDDINAYSYAYPLDYPSEKLVFKWVESRKPERYSSAAPLSPDARLRIVSERVDLTDNLVISISIGPPNSRLTSKEKKTWSAKEVADSVLSDKSALRVTSSQRLEESSVLDAHASDIDGEPYWYYEYLVRKSPTKIAEASKLYRHYISSTAERDGYLYTINASTLGKQWDKMGPVLERAVGSFRLLPPTDSYVPPYKDPWRFW", "length": 297, "molWeight": 33365, "crc64": "2DB521C129A840CC", "md5": "975E087397454E52DEB7308AFEDA6F74"}}
{"primaryAccession": "P82869", "text": "This is Peptidyl-prolyl cis-trans isomerase CYP37, chloroplastic protein, from Mouse-ear cress, contains 466 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P82869", "organism_name": "Mouse-ear cress", "protein_name": "Peptidyl-prolyl cis-trans isomerase CYP37, chloroplastic", "length": 466, "firstPublicDate": "2001-08-14", "FUNCTION": "PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASPLSSSTVVSHRLFFLHPSPLNRKFLFVKPKLPFNRTNSGDFRMRLHSTSSKTGTKELIHSCNSSIDSKLNTFEAGSKNLEKLVATILIFVQVWSPLPLFGLDSAYISPAEAVLYSPDTKVPRTGELALRRAIPANPSMKIIQASLEDISYLLRIPQRKPYGTMESNVKKALKVAIDDKDKILASIPVDLKDKGSELYTTLIDGKGGLQALITSIKKQDPDKVSLGLAASLDTVADLELLQASGLSFLLPQQYLNYPRLAGRGTVEITIEKADGSTFSAEAGGDQRKSATVQIVIDGYSAPLTAGNFAKLVTSGAYDGAKLNTVNQAVITEDGSGKVESVSVPLEVMPSGQFEPLYRTPLSVQDGELPVLPLSVYGAVAMAHSENSEEYSSPYQFFFYLYDKRNSGLGGLSFDEGQFSVFGYTIAGKDILGQIKTGDIIKSAKLIEGQDRLSLPVQNNNINEST", "length": 466, "molWeight": 50483, "crc64": "F160CC1CF95D89E5", "md5": "0C7A48659EB2C626C4259C307825DF5D"}}
{"primaryAccession": "P83326", "text": "This is Pectinesterase inhibitor protein, from Kiwi, contains 185 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83326", "organism_name": "Kiwi", "protein_name": "Pectinesterase inhibitor", "length": 185, "firstPublicDate": "2002-05-02", "FUNCTION": "Inhibits pectin methylesterase; may be involved in the regulation of fruit ripening", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the PMEI family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFSYCSSSLFVSLLLVILFISPLSQRPSVKAENHLISEICPKTRNPSLCLQALESDPRSASKDLKGLGQFSIDIAQASAKQTSKIIASLTNQATDPKLKGRYETCSENYADAIDSLGQAKQFLTSGDYNSLNIYASAAFDGAGTCEDSFEGPPNIPTQLHQADLKLEDLCDIVLVISNLLPGSK", "length": 185, "molWeight": 19893, "crc64": "ED5B2BA8EFDEDCD2", "md5": "B6FF3F2C2F288557A41F135084D42B0B"}}
{"primaryAccession": "P83411", "text": "This is Spodomicin protein, from Egyptian cotton leafworm, contains 40 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83411", "organism_name": "Egyptian cotton leafworm", "protein_name": "Spodomicin", "length": 40, "firstPublicDate": "2002-11-15", "FUNCTION": "Fungicide", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the diapausin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "VHVGPCDQVCSRIDPEKDECCRAHGYRGHSSCYYGRMECY", "length": 40, "molWeight": 4611, "crc64": "0F174C2F031A37BD", "md5": "D6EA0036FF96DB386CE7C636AB8557D4"}}
{"primaryAccession": "P83456", "text": "This is Alkaline phosphatase protein, from Atlantic cod, contains 477 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83456", "organism_name": "Atlantic cod", "protein_name": "Alkaline phosphatase", "length": 477, "firstPublicDate": "2004-01-16", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the alkaline phosphatase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "AGFPEQEPEPKFWNDWAQKTLDKALSLQTLNKNKAQNLILFLGDGMGVPTVTAARILKGQLRGQPGEEGQLEMDKFPFVALSKTYNTNAQVADSAGTATAYLCGVKANEGTVGVSAAAVRSQANTTQGNEVTSILRWAKDAGKSIGIVTTTRVNHATPSAAYAHCVDRDWYSDNEMPADAVEAGCKDIARQLFENIPDIDVIMGGGRKYMYPKNTTDVEYPGQPKHSGTRKDGRNLVKEWVDRNTEKKGHYVWNKKDLLSLNPTKVDYLLGLFEPADLPYDLERNKETDPSLSEMVEVAIKILRRNPNGFYLLVEGGRIDHGHHEGKDKQAIHEAVEMDRAIGRADLMTSTSDTLTVVTADHSHLFSFGGYTPRGNEIFGLAAFISDVDQKPFTAILYGNGPGYKLVNGARENVSTVDYQDNSYLAQAAVPLSSETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHAMAYAACIGQNR", "length": 477, "molWeight": 52198, "crc64": "0637907C62188DF9", "md5": "1D097238EEF0E047C62518446AE0C56B"}}
{"primaryAccession": "P83562", "text": "This is U7-hexatoxin-Mg1a protein, from Japanese funnel web spider, contains 82 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83562", "organism_name": "Japanese funnel web spider", "protein_name": "U7-hexatoxin-Mg1a", "length": 82, "firstPublicDate": "2003-06-27", "FUNCTION": "Induces flaccid paralysis when injected into lepidopteran larvae, Intracranial injection into mice causes awkwardness of movement and laboured respiration until death", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the rTX family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRTIVFLIVSILLLSSAVLMLAEGNAASHELQEYPIEESLEEQRKCVDGSCDPYSSDAPRCCGSQICQCIFFVPCYCKYRGK", "length": 82, "molWeight": 9159, "crc64": "80D33F80A7EC6685", "md5": "E91A707D333A8B85FAFEA6036C208881"}}
{"primaryAccession": "P83636", "text": "This is Molt-inhibiting hormone protein, from Spinycheek crayfish, contains 106 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83636", "organism_name": "Spinycheek crayfish", "protein_name": "Molt-inhibiting hormone", "length": 106, "firstPublicDate": "2004-01-16", "FUNCTION": "Inhibits Y-organs where molting hormone (ecdysteroid) is secreted, A molting cycle is initiated when MIH secretion diminishes or stops", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the arthropod CHH/MIH/GIH/VIH hormone family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVNQVAQCFTVRRVWLVVVVGLLVHQTTARYVFEECPGVMGNRALHGKVTRVCEDCYNVFRDTDVLAGCRKGCFSSEMFKLCLLAMERVEEFPDFKRWIGILNAGR", "length": 106, "molWeight": 12135, "crc64": "F6254BCBEE15ED97", "md5": "21734846ADB26452FF6F437FD58B9795"}}
{"primaryAccession": "P83773", "text": "This is Acetyl-CoA hydrolase protein, from Yeast, contains 524 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83773", "organism_name": "Yeast", "protein_name": "Acetyl-CoA hydrolase", "length": 524, "firstPublicDate": "2005-01-04", "FUNCTION": "Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the acetyl-CoA hydrolase/transferase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSAILKQRVRYAPYLKKLRTGEQCIDLFKHGQYLGWSGFTGVGAPKVIPTTLVDHVEKNNLQGKLGFHLFVGASAGPEESRWAENNMILTRAPHQVGKPIAAAINDGRTQFFDKHLSMFPQDLTYGFYTKDKPNGSNLDYTIIEATAITEDGSIVPGPAVGASPEMISVSDKIIIEVNTKTPSFEGIHDIDMPVNPPFRQPYPHTSADFKIGKTAIPVDPEKVVAIVESTSGDKVPPNTPSDEQSRGIANHLIEFLEHEVKQGRLPANLHPLQSGIGNIANAVVEGLASSNFKNLTVWTEVLQDSFLDFFESGSLDYATATSIRLTNDGFKKFYDNWDTYSKKLCLRSQVVSNSPEIIRRLGVIAMNTPVEVDIYGHANSTNVMGSRMLNGLGGSADFLRNAKLSIMHTPSARPSKVDPTGLSCIVPMASHVDQTEHDLDVVVTEQGLADLRGLAPKARAKVIIDKCSHPDYKPQLQEYYDRSVFYATKKKTLHEPHILRDVFKMHLNFQENGTMKLDSWDQKF", "length": 524, "molWeight": 58005, "crc64": "199E55926290CB7A", "md5": "D25A716667EAAF8511FC5D02DBDE8D16"}}
{"primaryAccession": "P83783", "text": "This is Adenosylhomocysteinase protein, from Yeast, contains 450 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83783", "organism_name": "Yeast", "protein_name": "Adenosylhomocysteinase", "length": 450, "firstPublicDate": "2005-01-04", "FUNCTION": "Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the adenosylhomocysteinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSAPATNYKVADISLAAFGRKDIELSENEMPGLMYIRKKYGPSQPLKGARIAGCLHMTIQTAVLIETLVALGAEVTWSSCNIFSTQDHAAAAIAAAGVPVFAWKGETEEEYQWCIEQQLFAFKDGKKLNLILDDGGDLTSLVHEKYPEMLEDCYGLSEETTTGVHHLYKSLRDGKLKVPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKVAIVAGFGDVGKGCAMALHGMGARVIVTEIDPINALQAAVSGYQVAPMDEVASIGQIFVTTTGCRDIITGKHFEQMPEDAIVCNIGHFDIEIDVAWLKANAESVVNIKPQVDRYLMKNGRHVILLADGRLVNLGCATGHSSFVMSCSFSNQVLAQIALFNADNKEFREKFPEFAKTGPFDVGVHLLPKVLDETVARCHLDHLGAKLTTLTETQAEYLGIPEEGPYKADIYRY", "length": 450, "molWeight": 49072, "crc64": "85A6D18CE85517E3", "md5": "CAEB04AA6C02907A36028824FCAB4920"}}
{"primaryAccession": "P83911", "text": "This is Omega-ctenitoxin-Pr1a protein, from Brazilian Amazonian armed spider, contains 43 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83911", "organism_name": "Brazilian Amazonian armed spider", "protein_name": "Omega-ctenitoxin-Pr1a", "length": 43, "firstPublicDate": "2004-07-19", "FUNCTION": "Inhibits high-voltage activated calcium channels, Shifts the voltage-dependence for activation towards hyperpolarized membrane potentials for L- (Cav1), P/Q- (Cav2,1/CACNA1A) and R-type (Cav2,3/CACNA1E) calcium currents, Causes immediate agitation and clockwise gyration, followed by the gradual development of general flaccid paralysis when injected intracerebroventricular into mice at dose levels of 5 ug per mouse", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 02 (plectoxin) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "ACAGLYKKCGKGVNTCCENRPCKCDLAMGNCICKKKFVEFFGG", "length": 43, "molWeight": 4640, "crc64": "52293FC743EFE2D8", "md5": "5CA8620988B9FDB73BD31F22D4B70966"}}
{"primaryAccession": "P84285", "text": "This is Sterol O-acyltransferase 2 protein, from Yeast, contains 609 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P84285", "organism_name": "Yeast", "protein_name": "Sterol O-acyltransferase 2", "length": 609, "firstPublicDate": "2004-12-07", "FUNCTION": "Sterol O-acyltransferase that catalyzes the formation of stery esters", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the membrane-bound acyltransferase family, Sterol o-acyltransferase subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGRTNTSDQLNAISDKNTKRKSLALDNEYHNNSSSEDDSSKIELSYTIPDNNNIISQETTTSVEDVLSLSSAPQNELRLRKQKSNNQDSPVDLNGVIVDVSKREKIFLKRKRQIDNKHGSDKSKYLSRFNDITFKAKSSTIFESDEFYKTDFFGMYVLFWLATAFAMVNNLIHTYFENSTPILQWTVVKVFKRDLFKVGLVDLAMYLSTYFAFFVQYACKNGYLSWKKVGWWLQAAFDGLFLFFWLWIASEYCLDFPWIAKVFLVLHSLVFIMKMHSYAFYNGYLWSIYKEGLYSEKYLDKLTNGKVTLPKGHTKNETEKVLQESIAFTKYELEYQSHATTENPDDHHVFDIDQTDKSIAKLQQEGLIKFPQNITLFNYFEYSMFPTLVYTLNFPRTKRIRWSYVFGKTFGIFGLIFLMILIAENNLYPIVLRCEIARKLPVSERIPQYFFLLMDMIPPFLMVYLFTFFLIWDAILNAIAELSKFADRDFYGPWWSCTDFSEFANQWNRCVHKFLLRHVYHSSISAFDVNKQSAAIITFLLSSLVHELVMYVIFGTLRGYLLLFQMSQIPLIIMSRSKFMKDKKVLGNIICWFGFISGPSIICTLYLVF", "length": 609, "molWeight": 71347, "crc64": "884CD6EEAD9C7430", "md5": "2B3E718CC71809FE52E1ACF1D6B5EF78"}}
{"primaryAccession": "P84805", "text": "This is Cysteine-rich venom protein kaouthin-1 protein, from Monocled cobra, contains 239 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P84805", "organism_name": "Monocled cobra", "protein_name": "Cysteine-rich venom protein kaouthin-1", "length": 239, "firstPublicDate": "2006-04-04", "FUNCTION": "Inhibits calcium-activated potassium channels (KCa), voltage-gated potassium channel (Kv), and the calcium release channel/ryanodine receptor (RyR)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the CRISP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIAFSLLCLAAVLRQSFGNVDFNSESTRRKKKQKEIVDLHNSLRRRVSPTASNMLKMEWYPEAASNAERWANTCSLNHSPDNLRVLEGIQCGESIYMSSNARTWTEIIHLWHDEYKNFVYGVGANPPGSVTGHYTQIVWYQTYRAGCAVSYCPSSAWSYFYVCQYCPSGNFQGKTATPYKLGPPCGDCPSACDNGLCTNPCTIYNKLTNCDSLLKQGSCQDDWIKSNCPASCFCRNKII", "length": 239, "molWeight": 26846, "crc64": "CACB1E01F2A04554", "md5": "273BCAFE0F243A153A3A24AB2532AC83"}}
{"primaryAccession": "P85070", "text": "This is Nigrocin-2GRc protein, from Yunnanfu frog, contains 67 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P85070", "organism_name": "Yunnanfu frog", "protein_name": "Nigrocin-2GRc", "length": 67, "firstPublicDate": "2007-01-23", "FUNCTION": "Antimicrobial peptide active at least against the Gram-positive bacterium S,aureus but with otherwise unclear activity spectrum (PubMed:16487561, PubMed:16621155), Lacks hemolytic activity against rabbit or human erythrocytes (PubMed:16487561, PubMed:16621155)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTMKKSMLLLFFLGTISLSLCEQERNADEEERRDEEVAKMEEIKRGLLSGILGAGKNIVCGLSGLC", "length": 67, "molWeight": 7454, "crc64": "AE9994D55B0A48A7", "md5": "45079B63FB18234B672CF9CEF937A836"}}
{"primaryAccession": "P85071", "text": "This is Nigrocin-2GRa protein, from Yunnanfu frog, contains 66 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P85071", "organism_name": "Yunnanfu frog", "protein_name": "Nigrocin-2GRa", "length": 66, "firstPublicDate": "2007-01-23", "FUNCTION": "Antimicrobial peptide active at least against the Gram-positive bacterium S,aureus but with otherwise unclear activity spectrum (PubMed:16487561, PubMed:16621155), Lacks hemolytic activity against rabbit or human erythrocytes (PubMed:16487561, PubMed:16621155)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTLKKSQLLLFFPGTINLSLCQDETNAEEERRDEEVAKMEEIKRGLLSGILGAGKHIVCGLSGLC", "length": 66, "molWeight": 7282, "crc64": "F34AD177EB5A78CF", "md5": "D986CFA1F53235276F412CF42126F862"}}
{"primaryAccession": "P86483", "text": "This is Bombesin protein, from Palawan frog, contains 67 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86483", "organism_name": "Palawan frog", "protein_name": "Bombesin", "length": 67, "firstPublicDate": "2010-05-18", "FUNCTION": "Stimulates smooth muscle contraction in isolated rat stomach strip", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the bombesin/neuromedin-B/ranatensin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSLLPAVKVLPLGYLGIVLVFSLILRSAMVDFIQDAGKLERIDTYKREAQMIFGAPMWALGHLMGRK", "length": 67, "molWeight": 7491, "crc64": "850EAC2A8EF1CB4F", "md5": "0F0E1835696BAD3F79A926371C5A7E01"}}
{"primaryAccession": "P86718", "text": "This is Spiderine-2a protein, from Lynx spider, contains 171 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86718", "organism_name": "Lynx spider", "protein_name": "Spiderine-2a", "length": 171, "firstPublicDate": "2014-03-19", "FUNCTION": "Has antimicrobial, insecticidal, cytolytic and cytotoxic activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the spiderine family, Cationic/spiderine subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFALVLLGVCAFYLVNATGDLETELEASELQELQEALDLIAETPLESLEAEELEEARKFKLPKINWGKLASKAKDVYKKGQKLAKNKNVKKALKYGKQLAENLAAGEVHEPGTPVGNNKCWAIGTRCTDDCDCCPEHHCHCPAKSWTFGLIPCSCQVTESDKVNKCPPAE", "length": 171, "molWeight": 18821, "crc64": "F1FDED7F20B054E3", "md5": "B970CBD2264D45B073D07AA9BFCD9342"}}
{"primaryAccession": "P86937", "text": "This is Thymine dioxygenase JBP1 protein, from Trypanosoma brucei brucei, contains 839 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86937", "organism_name": "Trypanosoma brucei brucei", "protein_name": "Thymine dioxygenase JBP1", "length": 839, "firstPublicDate": "2011-07-27", "FUNCTION": "Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU), DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation, Also specifically binds to base J-containing DNA (J-DNA), Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized DNA base J and propagating J synthesis, Thymine dioxygenase activity and J-DNA-binding are independent functions", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TET family, JBP1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRRQVKKVLREKADDSMKPGWDVYQPSNDVVYAFNHYMQGSQIDAEAREKAEKAFQEAVKKHPFHNNADHAVDFHGTTVFRNAKGKVCGVLIPKALPSFATSMAADVLECAVARTSLRSALFGGVSPNSGIAGYFDYRGTPVELKCRKTSFTYEHTKEWRSVFPMIDYTSAIYKAALPDHWKAQDAAVPDVVRIHGSPFSTLTVNERFRTASHTDNGDFDNGYGVLAVLKGEYSGLSLALDDYGVCFNMQPTDVLLFDTHLFHSNTELEAKEANATWNRLSCVFYYRAALGEQPCVEEYRRRLKKAKEEKSTSLSFNHIEQKDNGENTNKPAPVYPVPLTPFSCAASAWALRGCAAAMLTRLHGLVRENASLMTELFGEPVEVADGLPRRAPEEIIPVHKHTNVQMHYLGGFSEKGDILNEAMNKRHYLDKENLQKMFGEEFVNIWTQSRTHWLQLVKKEWEHQKETNPTRTRFSWNNTSAMNFAFFDLCDVAKQLMCGAFGDREVNKKEEQSFWGMFAAHLDNACINEIGMLQGSMGMHKLNVKLKDYNFGGTRYLKDMPPEEQERRRRRRLEIEQARRRAPICNSESGDWLRNEAFDYQTEDVAVNYEREQWITPENNAKRFGFPERGVYGAEGAATGTISVLIVLPKPTNHRQKTCELPTSREADRIMKNPAAQRLLCAKPCNIGLSTSSNKSRTVLCGNIRIDKVFDGGSVGGKMYDFVIMRHLLAATTGEREPLECLVRWTSLARYCTFVVEVDLLDRHHYILKSEIGEEYSAVSEICFSALYSATYARDKVNLRTTPCLLSFIDKSGNMLESRFKFNGSPLNTVAFVVRRREK", "length": 839, "molWeight": 95230, "crc64": "72CEC5A3E3EEB342", "md5": "B693B0B3DC38FE3139BA13576421E84D"}}
{"primaryAccession": "P86994", "text": "This is Bombesin protein, from Sichuan frog, contains 67 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86994", "organism_name": "Sichuan frog", "protein_name": "Bombesin", "length": 67, "firstPublicDate": "2011-10-19", "FUNCTION": "Stimulates smooth muscle contraction in isolated rat stomach strip", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the bombesin/neuromedin-B/ranatensin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLLLSAVKTLLLAWLGIVLVFMSIIKSAMLDFLQEAGKLEGIETYKKEAQTSFMAPSWALGHLMGRK", "length": 67, "molWeight": 7441, "crc64": "E0D8C25C02D1C8F9", "md5": "DA6B83351FFDCF38489211D013AFFFE2"}}
{"primaryAccession": "P87113", "text": "This is C-8 sterol isomerase erg2 protein, from Fission yeast, contains 219 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P87113", "organism_name": "Fission yeast", "protein_name": "C-8 sterol isomerase erg2", "length": 219, "firstPublicDate": "1998-07-15", "FUNCTION": "C-8 sterol isomerase; part of the third module of ergosterol biosynthesis pathway that includes by the late steps of the pathway (PubMed:18310029), Erg2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol (By similarity), The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane, Firstly, the squalene synthase erg9 catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids, Secondly, squalene is converted into lanosterol by the consecutive action of the squalene epoxidase erg1 and the lanosterol synthase erg7, The lanosterol 14-alpha-demethylase erg11/cyp1 catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol, In the next steps, a complex process involving various demethylation, reduction and desaturation reactions catalyzed by the C-14 reductase erg24 and the C-4 demethylation complex erg25-erg26-erg27 leads to the production of zymosterol, Erg28 likely functions in the C-4 demethylation complex reaction by tethering erg26 and Erg27 to the endoplasmic reticulum or to facilitate interaction between these proteins, Then, the sterol 24-C-methyltransferase erg6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol, The C-8 sterol isomerase erg2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol, The sterol-C5-desaturases erg31 and erg32 then catalyze the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol, The C-22 sterol desaturase erg5 further converts 5-dehydroepisterol into ergosta-5,7,22,24(28)-tetraen-3beta-ol by forming the C-22(23) double bond in the sterol side chain, Finally, ergosta-5,7,22,24(28)-tetraen-3beta-ol is substrate of the C-24(28) sterol reductase erg4 to produce ergosterol (PubMed:18310029) (Probable), In the genus Schizosaccharomyces, a second route exists between lanosterol and fecosterol, via the methylation of lanosterol to eburicol by erg6, followed by C14-demethylation by erg11/cyp1 and C4-demethylation by the demethylation complex erg25-erg26-erg27 (PubMed:8586261) (Probable)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the ERG2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKLTKFLTVFIPFIAGLIYYIQKYHLRSFYQFDPAKLQELSKQSIALYANDTKALLYDLSDRLVAEYGDLITPVNQDEWVHNNAGGAMGTMFILHASFSEYLIFFGTPIGTEGHSGVHMADDYFTILRGRQLAASANDLEARVYLPGDQHVHPWGHTAQYSMPSGEPCFALELAQGWIVSMLPFGFMDGLFSTIDFGTLYKTVYFTAGRMLKSVLMGKF", "length": 219, "molWeight": 24671, "crc64": "82C5EE63E28A8375", "md5": "7301A27A39D8A8368036A38DF177C6A2"}}
{"primaryAccession": "P87323", "text": "This is Response regulator mcs4 protein, from Fission yeast, contains 522 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P87323", "organism_name": "Fission yeast", "protein_name": "Response regulator mcs4", "length": 522, "firstPublicDate": "1997-11-01", "FUNCTION": "Response regulator that coordinately controls the stress activated wak1-wis1-sty1 MAP kinase pathway and fission yeast cell cycle", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRIWFKKVPDGITSSVILSEDHLVDDLKDAIARKFPIRISQYYDAPELSIRVVAPPNASSELQSRELSPNESILFVMETYYPHGQDFNDALLVASPDTSVALRYRSSQLSSSTFESTPPVFSEYPPNIIPTPANETVPRIKQPSIALDSLESPVSAPSRHQSTYSYKGGPLNYNLRNASRTRSHQTLPSSNVNKTGVLLLPRSSRQQTLASRPSLPDLTSADKSQPSDEAESITRKNSIGMSTRSDESTAEKLAKAEVATPTNSRSISHSSLYTKQSGTAGVLPAVNADIDAANRMNPDISSQFPIADNKDPLNADTQAHLGFPSNQIDGIVGTSPVNVLTSPGIGAKAPFASLLEGVIPPINVLIVEDNIINQKILETFMKKRNISSEVAKDGLEALEKWKKKSFHLILMDIQLPTMSGIEVTQEIRRLERLNAIGVGAPKLTQPIPEKDQLNENKFQSPVIIVALTASSLMADRNEALAAGCNDFLTKPVSLVWLEKKITEWGCMQALIDWNGWCRFRGR", "length": 522, "molWeight": 57240, "crc64": "D99169D301F62460", "md5": "6A8489243722F6D09DB7A18171853F28"}}
{"primaryAccession": "P93009", "text": "This is Protein CutA, chloroplastic protein, from Mouse-ear cress, contains 182 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P93009", "organism_name": "Mouse-ear cress", "protein_name": "Protein CutA, chloroplastic", "length": 182, "firstPublicDate": "2005-08-16", "FUNCTION": "Involved in metal homeostasis, Specifically binds Cu(2+), The truncated isoform has less specificity in metal binding", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the CutA family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASSLTTRLSAVIGSRRSFPIVGAFCVLSTLSISSLSSSSPFKSGCAQSFSVVPLLRSKFSSKAFSSSIRMEESSKTVPSIVVYVTVPNREAGKKLANSIVQEKLAACVNIVPGIESVYEWEGKVQSDSEELLIIKTRQSLLEPLTEHVNANHEYDVPEVIALPITGGSDKYLEWLKNSTRN", "length": 182, "molWeight": 19771, "crc64": "CC178325DCF8439F", "md5": "5B495D3375E35D9B9B6FEB5E85EB3156"}}
{"primaryAccession": "P93032", "text": "This is Isocitrate dehydrogenase [NAD] regulatory subunit 2, mitochondrial protein, from Mouse-ear cress, contains 367 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P93032", "organism_name": "Mouse-ear cress", "protein_name": "Isocitrate dehydrogenase [NAD] regulatory subunit 2, mitochondrial", "length": 367, "firstPublicDate": "2007-01-09", "FUNCTION": "Performs an essential role in the oxidative function of the citric acid cycle", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRQSFSLLKNLRSIASGSKIQTRSVTYMPRPGDGKPRPVTLIPGDGVGPLVTNAVQQVMEAMHAPVYFEPFEVHGDMKSLPEGLLESIKKNKVCLKGGLKTPVGGGVSSLNVNLRKELDLFASLVNCFNLPGLASRHENVDIVVIRENTEGEYAGLEHEVVPGVVESLKVITKFCSERIAKYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCQEVAKKYPSIAYNEIIVDNCCMQLVARPEQFDVMVTPNLYGNLVANTAAGIAGGTGVMPGGNVGAEYAVFEQGASAGNVGKDTTEEQKNANPVALLLSSAMMLRHLQFPSFADRLETAVKRVIAEGNCRTEDLGGNSTTQEVVDAVIANLD", "length": 367, "molWeight": 39590, "crc64": "B5BC1C422AF757F7", "md5": "26EAF1DF9FDF15CADF981E7CAF74A214"}}
{"primaryAccession": "P93050", "text": "This is Probable LRR receptor-like serine/threonine-protein kinase RKF3 protein, from Mouse-ear cress, contains 617 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P93050", "organism_name": "Mouse-ear cress", "protein_name": "Probable LRR receptor-like serine/threonine-protein kinase RKF3", "length": 617, "firstPublicDate": "2009-11-03", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLFLRRIAVVFFVFTSFSAAQNSTCPLDFSVLEPFRRPKPDGATTCQYLLQGLRLLYSHHLRQTGSFLPPPESAASCWAALQSSVAGFLPRFDVRSTCGFQTPWISQGCMDITTRSQFESLIPNSSLATTAMRCNTSLESNTPCASCTQSLSAFQPYLSGPSLGNVSDCASFPSIYAAAFANSLGPTDKGTAKCLFQLDLASPTSSGANKVKVLVSSFSVLLVASVLVITAWFWYCRRKKSKLLKPRDTSLEAGTQSRLDSMSESTTLVKFSFDEIKKATNNFSRHNIIGRGGYGNVFKGALPDGTQVAFKRFKNCSAGGDANFAHEVEVIASIRHVNLLALRGYCTATTPYEGHQRIIVCDLVSNGSLHDHLFGDLEAQLAWPLRQRIALGMARGLAYLHYGAQPSIIHRDIKASNILLDERFEAKVADFGLAKFNPEGMTHMSTRVAGTMGYVAPEYALYGQLTEKSDVYSFGVVLLELLSRRKAIVTDEEGQPVSVADWAWSLVREGQTLDVVEDGMPEKGPPEVLEKYVLIAVLCSHPQLHARPTMDQVVKMLESNEFTVIAIPQRPIPLVACREEIDRSVSSSSGSGKLTSPTGYQAFSFGGDGPSGNTNTT", "length": 617, "molWeight": 67224, "crc64": "295D694B8563408A", "md5": "120206D811ABEF355D44F131DBAB538C"}}
{"primaryAccession": "P97586", "text": "This is Cell growth regulator with EF hand domain protein 1 protein, from Rat, contains 281 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P97586", "organism_name": "Rat", "protein_name": "Cell growth regulator with EF hand domain protein 1", "length": 281, "firstPublicDate": "2002-09-19", "FUNCTION": "Mediates cell-cell adhesion in a calcium-dependent manner, Able to inhibit growth in several cell lines", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSRWLMQMLMLPLLLLPLGQAAPKDGVARLDPEAQQQLTTNPFQPGPEQLRRLRDYLKGLEKMEEDPEQMNREQVLLYLFALHDFDQNGQLDGLELLSMLTAALAPGAAHFPINPVILVVDMVLETQDLDGDGLMTPAELINFPGEAPKRAESLPPALQEPQPAGSQPLLANSPLQSETQQSLGTKEEITSQVEAKRALEPEQEAGHHIETKVDALSPEGEARGQAESEGDAPGPREDAERQVESKDNEGEAKDLPAETLETQNTPNVVEAHSIQLENDEI", "length": 281, "molWeight": 30835, "crc64": "C8195BED34BB1549", "md5": "AE1E07142E4671CF2E13CD1E05243046"}}
{"primaryAccession": "P98137", "text": "This is Complement component C8 beta chain protein, from Rabbit, contains 590 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P98137", "organism_name": "Rabbit", "protein_name": "Complement component C8 beta chain", "length": 590, "firstPublicDate": "1996-02-01", "FUNCTION": "Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the complement C6/C7/C8/C9 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKKSWTWTWRVPAELLLLCAALGCLCVPGSRSERPRSLEPTVVNRSLAKSRHSRSVDATPMPIDCELSSWSSWTMCDPCQKKRYRHAYLLRPSQFNGEPCNFSDKEVEDCATSRPCRSQVRCEGFVCAQTGRCVNRRLLCNGDNDCGDQSDEANCRKIYKKCHHEMEQYWAIGSLASGINLFTNSLEGPVLDHRYYAGGCNPHYILDMRFRKPYNVESYTPQTQGKYKFALAEYESYSDFERNVMEKTYSKSTFNLGFKIPSIFEFGINTESDQLMNYISRTKRFSHTKSKFLHARSALEVAHYKLKPRNLMLHYDFLQRVQRVPLEYSYGEYRDLFRDFGHHFITEAVLGGIYEYTLIMNKEAMERADYSLNDVQACAKNDFKLGAAIEEVYVSLGVSTSKCRGILNEIKDRNKRDTMVQDLVVLVRGGASEHITALAYSDLPTADLMQEWGDAVQYNPAIIKIKVEPLYELVTATDVAYSSTVKQNMRQALEEFQGEVSPCRCAPCQGNGVPVQKGSRCDCICPVGFQGSACEITSRKNVPIDGRWSCWSRWSSCSGGQKTRRRQCNNPAPQDGGSPCSGPASETLAC", "length": 590, "molWeight": 66858, "crc64": "54ED81B15F2CCC2C", "md5": "45A320FC851E7EE8610F0AE15ED275AB"}}
{"primaryAccession": "Q00870", "text": "This is Kievitone hydratase protein, from Nectria haematococca, contains 350 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q00870", "organism_name": "Nectria haematococca", "protein_name": "Kievitone hydratase", "length": 350, "firstPublicDate": "2013-12-11", "FUNCTION": "Converts fungitoxic kievitone to the less toxic kievitone hydrate, and thereby protects the pathogenic fungus against this phytoalexin", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMISSVLVAGVVAVSAALASKHPKQYSFKPEDAETIWNGDIPVLYDFGDSQSASYSGSWWTSSYITGTNGEQYLVISHYLDTPVFTYFRASTLNLETLDYNQFITLGNNTANSTTLDVKVGDNGIQSLTADNISQQRAYANDENVTFDITFDATSRVISNAGAGVFQFGPSITYEWGLPNCRTQGSVTDTGGKNITVDPAKSFTWYDRQWGTAAVTSGNWTWFQMHIPETSYKLSVWIIDNDVTNQFSRFATIRGDNDEFQVLPLEWKPIYDRTYQSTAADILYPLDWELDISGFGVFQLSSILDDQEIVGTTAIQTAYEGFVTFNGTVHNKKVQGYGLVEVVYSNWESL", "length": 350, "molWeight": 38970, "crc64": "CE09B07A7B34C91B", "md5": "52127DAC4722EF1FBF67528702B60585"}}
{"primaryAccession": "Q00IB6", "text": "This is RNA polymerase II C-terminal domain phosphatase-like 4 protein, from Mouse-ear cress, contains 440 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q00IB6", "organism_name": "Mouse-ear cress", "protein_name": "RNA polymerase II C-terminal domain phosphatase-like 4", "length": 440, "firstPublicDate": "2009-05-26", "FUNCTION": "Processively dephosphorylates 'Ser-2' and/or 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1), This promotes the activity of RNA polymerase II (By similarity), Required for normal plant growth", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVASDSPVHSSSSSDDLAAFLDAELDSASDASSGPSEEEEAEDDVESGLKRQKLEHLEEASSSKGECEHPGSFGNMCFVCGQKLEETGVSFRYIHKEMRLNEDEISRLRDSDSRFLQRQRKLYLVLDLDHTLLNTTILRDLKPEEEYLKSHTHSLQDGCNVSGGSLFLLEFMQMMTKLRPFVHSFLKEASEMFVMYIYTMGDRNYARQMAKLLDPKGEYFGDRVISRDDGTVRHEKSLDVVLGQESAVLILDDTENAWPKHKDNLIVIERYHFFSSSCRQFDHRYKSLSELKSDESEPDGALATVLKVLKQAHALFFENVDEGISNRDVRLMLKQVRKEILKGCKIVFSRVFPTKAKPEDHPLWKMAEELGATCATEVDASVTHVVAMDVGTEKARWAVREKKYVVHRGWIDAANYLWMKQPEENFGLEQLKKQLTEEE", "length": 440, "molWeight": 50264, "crc64": "7712641DC888B82B", "md5": "C68A26648DAFCCF5442A6E617EF7FA52"}}
{"primaryAccession": "Q01117", "text": "This is Alpha-amylase 1 protein, from Yeast, contains 624 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q01117", "organism_name": "Yeast", "protein_name": "Alpha-amylase 1", "length": 624, "firstPublicDate": "2003-09-19", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 13 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLLINFFIAVLGVISLSPIVVARYILRRDCTTVTVLSSPESVTGSNHVQLASYEMCGSTLSASLYVYNDDYDKIVTLYYLTSSGTTGSTLALILPVWSNNWELWTLSAIAAGAVEITGASYVDSDTSVTYTTSLDLPLTTTSASVPTGTAANWRGRSIYQVVTDRFARTDGSITYSCDVTDRVYCGGSYRGIINMLDYIQGMGFTAIWISPIVENIPDDTGYGYAYHGYWMKDIFALNTNFGGADDLIALATELHNRGMYLMVDIVVNHFAFSGNHADVDYSEYFPYSSQDYFHSFCWITDYSNQTNVEECWLGDDSVPLVDVNTQLDTVKSEYQSWVKQLIANYSIDGLRIDTVKHVQMDFWAPFQEAAGIYTVGEVFDGDPSYTCPYQENLDGVLNYPVYYPVVSAFQRVGGSISSLVDMIDTLKSECIDTTLLGSFLENQDNPRFPSYTSDESLIKNAIAFTILSDGIPIIYYGQEQGLNGGNDPYNREALWPTGYSTTSTFYEYIASLNQIRNHAIYIDDTYLTYQNWVIYSDSTTIAMRKGFTGNQIITVLSNLGSSGSSYTLTLSNTGYTASSVVYEILTCTAVTVDLSGNLAVPMSGGLPRVFYPESQLVGSGICSM", "length": 624, "molWeight": 68877, "crc64": "87EB16534F5A9A9F", "md5": "C783596B04BF2FC7480987EAA6B4906B"}}
{"primaryAccession": "Q01163", "text": "This is Small ribosomal subunit protein mS29 protein, from Baker's yeast, contains 450 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q01163", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein mS29", "length": 450, "firstPublicDate": "1993-04-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane, mS29 binds GTP and is probably an active GTPase, GTP hydrolysis may be linked to subunit association (PubMed:25609543, PubMed:28154081), mS29 also has an extraribosomal function, being required for maintenance of mitochondrial DNA (PubMed:11017876)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mS29 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRMSTSRFIGQRLFTTARSLQAAKPAPKGKTQGFSKKSSSVSSYSSAKRVTPGSLYKNWTNTTHTAQLQQTAVPLALPIFNFDDISKTLNKVVSYSNKQYKSLHHLGSFKKSQFNELFQKPVCLVREDATNSFLKKLVSHPVKKFIITGEPGVGKTVLLSQAHAYAVDSKQIIINISYPELFLNGRNDFSYDDDLKLFIQPMYLKKLIRKILKANDPALLKSIELSKDYKFSNANPKNASVKPFVTLNKTKNTVLDLLSVMTHPHNRGKLMKAIIDELSVQSKVPIMFTVDNFSKVLTTAYSAYRNTENKQIYSLDLQMGKLMMDIISGETKFANGESSTILAISGVDRTNKTLPVALGKIPVDPYVTRYHYEPKFVELLQKGNVTEFEVPKLNKQEVNELIDYYKQSNVLLDKDITGKKWENLIDEKYFLSGNGNPRELLKSLVLSHR", "length": 450, "molWeight": 50867, "crc64": "DCE220C14D020AE2", "md5": "E74A9002D8A4A8970E832879C1165F6E"}}
{"primaryAccession": "Q02204", "text": "This is Large ribosomal subunit protein mL50 protein, from Baker's yeast, contains 264 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02204", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein mL50", "length": 264, "firstPublicDate": "1993-07-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mL50 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSLLKLHCIRPLPQRSVWLSGYKQKARCIHSSAANGDFMSWFKRKKQEEHQEPVKDTKQLIKDIEEGTNEASSQSSSNNKNRLELIPENFIGEGSRRCKRQKELKLAVSSAPFNQWLSRDKITSDNQLDDMILQATEKTLGKVDQDVQFSDLVAKFQFTKFLQSKSGYLIPDYELTTLSTPLQFKRYIKEKILPSANDPKLAYKEAEPNAIHPFSDNYASPNIYVVNDVTSKEQKSKYDTIMKEIQKLEDDATRKALETARSA", "length": 264, "molWeight": 30271, "crc64": "6418F9BD92910DDA", "md5": "360796BE3050E3624A1C150FFDE14584"}}
{"primaryAccession": "Q02648", "text": "This is tRNA (uracil-O(2)-)-methyltransferase protein, from Baker's yeast, contains 567 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02648", "organism_name": "Baker's yeast", "protein_name": "tRNA (uracil-O(2)-)-methyltransferase", "length": 567, "firstPublicDate": "2006-09-19", "FUNCTION": "tRNA (uracil-O(2)-)-methyltransferase, which catalyzes the formation of O(2)-methyluracil at position 44 (Um44) in tRNA(Ser)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TRM44 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTGDGSAHISKNNQNQHKDRFKFIVNDKSILGPQWLSLYQTDGKVTFAKSHFEQAMMNVIREPNINSTVILRADILKEINHAAEAGSEPKFDESVLKKFEIDNGNESGEEDVKKINIEDLNIRSCETSESLKLSPVHEFVRRIIPRNFYKDAIINQTCLILNSKDPNFQETSLIVYTPHINSEKDCPFYIPRTQSVGILLHQSVLSVHYIPFPEDKTAFTDESERVVRTAYRLLQTANKHSKGVMQGYEKRVNHDQVVNKVNFQNTYIVLKKKYSKFLVENWAESTDPKKHVFEDIAIAAFLIELWIKVYGPDFRSKMQFRDLGCGNGALCYILLSESIKGLGIDARKRKSWSIYPPEVQSSLKEQVIIPSILLRPHPALKRQVPHLEHNGRFFPVKVTHEVIAPATVVYSSEDLLKSPQVNTAEFPPDTFIIGNHSDELTCWIPLLGHPYMVIPCCSHNFSGQRVRFNVRKRSPRSNEIKNQNNSKSTYSGLVDHVEYISSRVGWKVEKEMLRIPSTRNAAIIGVENATLKHFPTQAVYDMIWEDGGAEGWIQNTMSLLKRNPRNH", "length": 567, "molWeight": 64855, "crc64": "5374D45014C047C0", "md5": "80EE1AE895128794AD40DF10C742C122"}}
{"primaryAccession": "Q02866", "text": "This is Protein MUK1 protein, from Baker's yeast, contains 612 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02866", "organism_name": "Baker's yeast", "protein_name": "Protein MUK1", "length": 612, "firstPublicDate": "2006-10-31", "FUNCTION": "Putative GTPase-activating protein", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MARQLFTPPITNPRFDPNQSIRESYKNTTGGMQFQQNLHEDQNDNERSSCDGDENSTTGERLENNKSPILTKQEIDEALNTVTNLPPELSKLIDIFIDDLKQPKYVRPLSVLQLSSLFQSFYIKFDKASFQHVSSANNNGYYFSGGGSSSFLAAKETLSSGLSGIFGRSRSSSGNSLMRPRRSSSLFSNESISNSTNATQMLSPEEIKKQLKINELNNMKIEKYMELCERDVFKKILIVGTSVSSPNKMKTFKPHQLQTFKVGNLFRNSVEFTEYNKLLNEKILCLSKLSTMNKINLIKFLSLNNGIDPEPKFEEIKDILYEFTYHSISPCEKIKALLKLHEIMTYSQEMSNDDYLSLLIYYIITIVPRDIFLNAEFIRLFRYKKKLVETESFALTNLEAALVFVEGLTKNDFSNELQDKLTVNESKILENSISSRVSLPSKTAIMHKNNGNNGSNLGDIVTPTIQRPDVTRSNSYDGFRTVFDSSLKNIIGKIRSYTPPHPNNTSNNNLHSSNNLNIPRSSSQLSMELSNRDTTEMSRDGSRSTSSSSRSSASLEHGNREFTGDLTVTASINGADKKEFQKSWKKYKGYKFEDLTICELRDLFEIYQKMMQ", "length": 612, "molWeight": 69538, "crc64": "C743D0436E541978", "md5": "A87ACAE778955091AC49380AFEB0D1F1"}}
{"primaryAccession": "Q03370", "text": "This is Peroxisomal membrane protein PEX29 protein, from Baker's yeast, contains 554 amino acids, is membrane-bound, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03370", "organism_name": "Baker's yeast", "protein_name": "Peroxisomal membrane protein PEX29", "length": 554, "firstPublicDate": "2006-10-03", "FUNCTION": "Involved in the regulation of peroxisome number, size and distribution", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the PEX28-32 family, PEX29 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDSVTNFFWNDTYNAGTPTRSTLKGKKVQNGIDGKSQAKKESISSGSRTSDPTRGSLPSSSGQPTSGGGFPSTSNIQKMMADTLVEKIIKMALPPSSKTAVDTIHHRMVAGKERPKLSVQITSRNFIQMNSRLGVPFMIMDELIKILNWTNPAYTVSIMFLYTLIILKPFQMLSSLPIFYLLFCVMVPQYLYIHKPNPTSYLDNNQTPAQGPPLRRPEVPKPVPELSQEFVLNLTDLQNHMLLYVKFYDFTLLILQKFAFFTNEAISSFYFIVLLIIATLNFLYMDKFIKLIPMRPVLILLGWGFFIASHPSNREYLLTKLNSEETRLKTLTISTNLESKILQHLKLIEAREHRLVMIFEIQKYLPEYKEWRPVGFSDDDYSLFSSLRIYQRRIEENSVKSLEEIEPPKDWEWEANSHWVLDLDPKEWVEDEFIQYVEIDSETKWVYDLNLDGQRGSYRRRMWTNSCVRKKLDSGISSNLGEEEVVNPLREETYRQGVHGVTKGSMSGGLTHSSDDDRADEESINGTIPNLNNIDADASYPSIEELTDTLNSTI", "length": 554, "molWeight": 63543, "crc64": "C2EB849C36FB69EB", "md5": "698FE4DAF479C5892472423E9278F122"}}
{"primaryAccession": "Q03562", "text": "This is Beta-1,4-mannosyltransferase bre-3 protein, from Caenorhabditis elegans, contains 455 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03562", "organism_name": "Caenorhabditis elegans", "protein_name": "Beta-1,4-mannosyltransferase bre-3", "length": 455, "firstPublicDate": "1994-02-01", "FUNCTION": "Glycosyltransferase with a proposed role in glycosphingolipid biosynthesis (PubMed:12944392, PubMed:10924467), Involved in susceptibility to pore-forming crystal toxins in conjunction with bre-1, bre-2, bre-4 and bre-5 (PubMed:12944392, PubMed:10924467), Involved in resistance to the nematotoxic C,cinerea galectin Cgl2 (PubMed:20062796), Has a role in determining brood size (PubMed:12944392, PubMed:10924467)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the glycosyltransferase 2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNCEVKHALHCAVLVAWIVCFAYFCGVFTEPVEGSVPESPVASYGLIWTVCLYLLRFTALLVLPQCLCNLGGLMMFNAFREKVQLKAAPLLSPFVCFRVVTKGNFPLLVKENIDTNMKTCFEAGMENFIFEVVTDKAINLPPNPRVREVVVPTVYKTKSGAKFKARALQYCLEDDVNILQPTDWIVHLDEETLLTTNAICGILNFCEDGKHQFGQGVITYANGDIVNWLTTLSDSFRVADDMGKLRFQFKLFHKPLFGWKGSYVVTQVEAERDVSYDHGMEGSIAEDCFFSMVAMKHGYSFDFIEGEMHEKSPFTMWDFLQQRKRWLQGILLTVHSSKIAVVHKALLALSLYAWATMPLTSLQVFLCPLFPLPRCLPFDFLLSFVGALNLYMYIFGVVKSFSHKYRNSLLRLAMYLAGALMTIPFNILIENAAVLVGMFGRKDQFYIVNKDIQTV", "length": 455, "molWeight": 51591, "crc64": "28A3605A22C38F04", "md5": "3AEE76566C5271CE649733DFB25C30B7"}}
{"primaryAccession": "Q03776", "text": "This is U1 small nuclear ribonucleoprotein component PRP42 protein, from Baker's yeast, contains 544 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03776", "organism_name": "Baker's yeast", "protein_name": "U1 small nuclear ribonucleoprotein component PRP42", "length": 544, "firstPublicDate": "2006-11-28", "FUNCTION": "Essential component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA, Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway, U1 snRNP is cotranscriptionally recruited to intron-containing genes, Required for U1 snRNP biogenesis", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDKYTALIHDENFSTLTLNVSRYPKSLAYWEKLLNYIVKASAPICKSTEPQLLKLIRCTYSSMLNEFPYLENYYIDFALLEYKLGNVSMSHKIFQRGLQAFNQRSLLLWTSYLKFCNNVISHQKQLFKKYETAEEYVGLHFFSGEFWDLYLEQISSRCTSSKKYWNVLRKILEIPLHSFSKFYALWLQRIDDIMDLKQLSQLTSKDELLKKLKIDINYSGRKGPYLQDAKKKLKKITKEMYMVVQYQVLEIYSIFESKIYINYYTSPETLVSSDEIETWIKYLDYTITLQTDSLTHLNFQRALLPLAHYDLVWIKYSKWLINSKNDLLGAKNVLLMGLKFSLKKTEIIKLLYSVICKLNEYVLLRNLLEKIESSYSDNVENVDDFEIFWDYLQFKTFCQNSLYSSRYSDSQSNGLLNKELFDKVWKRLSCKEKKSGQEILLNNLVQFYSKDTVEFVEKNIFQKIIEFGWEYYLQNGMFWNCYCRLIYFDTSRSYLDKRQYIVRKIWPQIDKKFAQSVLPSLTEFCESYFPEEMDTLEEMFTEEP", "length": 544, "molWeight": 65145, "crc64": "7F6790FFD0ECEB80", "md5": "D579A051EA521A81FDF886ED181AAABB"}}
{"primaryAccession": "Q03860", "text": "This is Golgi apparatus membrane protein TVP15 protein, from Baker's yeast, contains 143 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03860", "organism_name": "Baker's yeast", "protein_name": "Golgi apparatus membrane protein TVP15", "length": 143, "firstPublicDate": "2006-06-27", "FUNCTION": "Golgi membrane protein involved in vesicular trafficking", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the TVP15 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSVIPPKFFKIANISIGCIDIIAALSQLTYIFTNLNVFLLAVYGLALSVPIVYLEFKVPSNLYRYASFYFSFLGRGLSYILLSLIISFGGIYNILAGMFTFILGVAFIVFHFSQFVEEPANFRAPGSSLSIGDDDIDDDDDMI", "length": 143, "molWeight": 15882, "crc64": "395F700FBB14C569", "md5": "004FC151250E4C2B18D94A6BD1CF75DB"}}
{"primaryAccession": "Q03937", "text": "This is Meiosis-specific protein HED1 protein, from Baker's yeast, contains 162 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03937", "organism_name": "Baker's yeast", "protein_name": "Meiosis-specific protein HED1", "length": 162, "firstPublicDate": "2006-10-03", "FUNCTION": "Involved in regulation of meiotic recombination and repair of DNA damage, Inhibits RAD51-mediated recombination when the meiotic recombination machinery is impaired", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQQRSNRRSCSYIPLGVHNNAEKSLCTEVAPARKNKRSITTSPIVNINVVERRLFNLELEKQQLRAKNLSENTGGGSPNGGAYLDAKKGVREQDQYQGGPSKELDRLQPPPSMKKSPPRKKKSLKDLIYETNKTFYQVDSNKVKYKVGLSKKQLLPSKTVDN", "length": 162, "molWeight": 18258, "crc64": "CC97293CD51A0FD4", "md5": "80661E3D52E8FDDED2A28350414B595D"}}
{"primaryAccession": "Q04213", "text": "This is ISWI one complex protein 4 protein, from Baker's yeast, contains 475 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q04213", "organism_name": "Baker's yeast", "protein_name": "ISWI one complex protein 4", "length": 475, "firstPublicDate": "1997-11-01", "FUNCTION": "Functions as component of the ISW1B complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA, The ISW1B complex acts within coding regions to control the amount of RNA polymerase II released into productive elongation and to coordinate elongation with termination and pre-mRNA processing", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSEAIFQPTDIVLAKVKGFSAWPAMIIPNELIPDNILKTKPVSVHKGKSGSDKKANEDIDADMESEARDREQSEEEEDIEDFGESEANPEKFIIYTPVLKFRKNDTLKSTYCVKFFCDDSYIWVKPMDMKILTSEDCRKWLSGKQRKNKKLIPAYEMAMRGKNGIDIWEFVEYGSYGKPDEEEYVEEEEEENEPEKKAIRPTRSSSRQRQKRASETEKSEGGNSNKRKRVTRSTRQQAIDASEEEEEEEEEKVQEAVRKRPQRTKTKKVVVSKTKPNPKTKAKKEKPKPPKPIKYHFEDDEDWSIVGLGPQDLSIEKTMDPIAKKLSQKKNLEKHVEIKLDLEDKLAGINKLLCDVLCSAINQAVSIKDDFEIILDELQIALDTRGSRNEFITIFQSNNSLLLNFRILFNLRKRELNKWDLWDRFQDIFKHIYSYQFIPDTEDWQLEQNMEIEEMDREKPSFSEDVKEEESKVGA", "length": 475, "molWeight": 55427, "crc64": "DFD6189E81178060", "md5": "6DE17C7DE272B808C3EF5306C3565D84"}}
{"primaryAccession": "Q04712", "text": "This is RNA polymerase I-specific transcription initiation factor RRN11 protein, from Baker's yeast, contains 507 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q04712", "organism_name": "Baker's yeast", "protein_name": "RNA polymerase I-specific transcription initiation factor RRN11", "length": 507, "firstPublicDate": "1997-11-01", "FUNCTION": "Acts as component of the core factor (CF) complex which is essential for the initiation of rDNA transcription by RNA polymerase I, After binding of UAF (upstream activation factor) to an upstream element of the promoter, CF is recruited in a SPT15/TBP-dependent manner to form a preinitiation complex", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFEVPITLTNRKFAQRRKLKYQYINYISRRFDRISKKSTTTDSLPTPENSAAENNDEEEGQNSEAGTYRRSVLQQKKRRRERHWRSVVGEIYSTTESETDSQEEETEEGGEHDTGIDKEDSDEERKFWKKYEKPEKSFEIWRTVSSQNKQPINKQKMTYHNFKKIEKIPLRKMEIPLLHCTKENKLYFQSISRGLEPLKTSTSEVRNYRTRHIVTLTDLLHLNVSRHNWSLAYKIFATLIRIPGVQIKSLWGIGVEILDNLSNSSSGLDFLQWMCQIYSSKSRFVQNINYRSIVPPFQTGSRTHTAKFAITYLWSSLINCQKSMEPSSNIIDKPFDTENDLLQELIDKISEWVLTPPFMEDAEVWFIYASCHLLKADTLSRQFVNDNKNNDLIGLDRDIKINQVIKHIHYVRTFLKICLDKGGFAVPSRLIENQLKSFESRLYGEAQDIQERDVANVYDSIDNSSVENSFGDVYETNAEFLDTQLMDLSPEDNGLDEMHYSDEDSSE", "length": 507, "molWeight": 59254, "crc64": "726B0963F0E79783", "md5": "BB2BC54E646F57F2CC996AB0351D3145"}}
{"primaryAccession": "Q04969", "text": "This is Signal peptidase complex subunit 2 protein, from Baker's yeast, contains 178 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q04969", "organism_name": "Baker's yeast", "protein_name": "Signal peptidase complex subunit 2", "length": 178, "firstPublicDate": "1997-11-01", "FUNCTION": "Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:8910564, PubMed:10921929), Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (PubMed:8910564, PubMed:10921929)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the SPCS2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSAKPINVYSIPELNQALDEALPSVFARLNYERSYALLDAKLYIGYSIAVVAGLSFFLDKKFERDQIVTYQKLLVGAYFVLSLLFWYFSRFIEKGTVYVGKRRGTKEEIYVKTKFEKNEPLYLVELVQKKKGENSKKELKAKLEVNKVFNESGYLQNDAYFKWFSEQHNVLDTKKNE", "length": 178, "molWeight": 20802, "crc64": "432742B2E1E5382C", "md5": "B8AFED225C2098AAD2D11A21B056FCD7"}}
{"primaryAccession": "Q05635", "text": "This is Ribonuclease H2 subunit B protein, from Baker's yeast, contains 350 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05635", "organism_name": "Baker's yeast", "protein_name": "Ribonuclease H2 subunit B", "length": 350, "firstPublicDate": "2006-09-05", "FUNCTION": "Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids, Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication, Mediates the excision of single ribonucleotides from DNA:RNA duplexes", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RNase H2 subunit B family, Highly divergent", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTVSNIGGEERLIILPDDYETSKTINTFTLPPPSNITSKPRIELFENINGKLYEIRSFQFGKGPSYSHEEDLANDKYHYTKENHPIKSTFIVNTSDPTDGYVFNSSKIHFCSLYDIAFSLIGFYYRNSVSADEQDYSNSSDTGENQKSNSKTNEKFLTVRDYHDFLTDNHDKNWENISLSRLKSGLAKVSETIEEAGDVYYKITSAMITQFLLGKVSKIVENFPPSIPTLKNAPTEIKQCYKVVMATNLLVSLIPRAAYHNLLTFSPTMDSGCLNPDIKASFIELENYETTNELQNAERELLMKSAMNVGLNSNGRVSLPVKKVTKKIVQNKKPKVAIGKGAIDGFFKRK", "length": 350, "molWeight": 39484, "crc64": "68578B3018579583", "md5": "ADE7D9099829F5D40F2D222ACA49FF98"}}
{"primaryAccession": "Q05924", "text": "This is Phosphatase DCR2 protein, from Baker's yeast, contains 578 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05924", "organism_name": "Baker's yeast", "protein_name": "Phosphatase DCR2", "length": 578, "firstPublicDate": "2005-02-01", "FUNCTION": "Required for cell cycle progression, Has a role in the completion of START", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIRLPRLYQRYLLYLVVFVVIALFYFLQAPRVEEHIGFDLALPISHVDNLWFQNKGLEGFSNDDKLVVNIGYDECFHIGRFYEGCFNRHELKSTLTDGHQYLQRKRIHKDLRGSFGRRWFGKSEYLYYDVLYPALVDYFGSNLEKLNVEAVTGISKYPKDKSLPFMDVSITFEPISIELLQKRSYISDINILFGVDCIQPIANWTLQKEFPLVKYRYSEPAYLTYKFVGTRPVDTGAQRLQETDEGKFKIVQLADLHLGVGESECIDEYPKHEACKADPKTETFVQQVLDIEKPQLVVFTGDQIMGDRSIQDSETVLLKAVAPVIARKIPWAMVWGNHDDEGSLTRWQLSEIASVLPYSLFKFSPHDTHDNTFGVGNYIYQIFSNNDTEVPVGTLYFLDSHKYSTVGKIYPGYDWIKESQWKYIEDYHDVNLKFKTGLSMAFFHIPLPEYLNIESKTHPGEKNPLIGMYKEGVTAPKYNSEGITTLDRLSVDVVSCGHDHCNDYCLRDDSTPNKIWLCYGGGGGEGGYAGYGGTERRIRIYEINVNENNIHTWKRLNGSPKEIFDFQSMLDGNSPESV", "length": 578, "molWeight": 66463, "crc64": "8B9AECAEACF2564C", "md5": "BA429FA5589822C0CF625A6577CB8273"}}
{"primaryAccession": "Q05926", "text": "This is Glutaredoxin-8 protein, from Baker's yeast, contains 109 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05926", "organism_name": "Baker's yeast", "protein_name": "Glutaredoxin-8", "length": 109, "firstPublicDate": "2006-12-12", "FUNCTION": "Glutathione-dependent oxidoreductase with lower activity compared to the other members of the glutaredoxin family, The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the glutaredoxin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSAFVTKAEEMIKSHPYFQLSASWCPDCVYANSIWNKLNVQDKVFVFDIGSLPRNEQEKWRIAFQKVVGSRNLPTIVVNGKFWGTESQLHRFEAKGTLEEELTKIGLLP", "length": 109, "molWeight": 12519, "crc64": "3353EFB47A61574A", "md5": "8646A59D611D76114B98ED57D79B2865"}}
{"primaryAccession": "Q05JG2", "text": "This is Abscisic acid 8'-hydroxylase 1 protein, from Rice, contains 471 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05JG2", "organism_name": "Rice", "protein_name": "Abscisic acid 8'-hydroxylase 1", "length": 471, "firstPublicDate": "2007-05-29", "FUNCTION": "Involved in the oxidative degradation of abscisic acid", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the cytochrome P450 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGAFLLFVCVLAPFLLVCAVRGRRRQAGSSEAAACGLPLPPGSMGWPYVGETFQLYSSKNPNVFFNKKRNKYGPIFKTHILGCPCVMVSSPEAARFVLVTQAHLFKPTFPASKERMLGPQAIFFQQGDYHAHLRRIVSRAFSPESIRASVPAIEAIALRSLHSWDGQFVNTFQEMKTYALNVALLSIFGEEEMRYIEELKQCYLTLEKGYNSMPVNLPGTLFHKAMKARKRLGAIVAHIISARRERQRGNDLLGSFVDGREALTDAQIADNVIGVIFAARDTTASVLTWMVKFLGDHPAVLKAVTEEQLQIAKEKEASGEPLSWADTRRMKMTSRVIQETMRVASILSFTFREAVEDVEYQGYLIPKGWKVLPLFRNIHHNPDHFPCPEKFDPSRFEVAPKPNTFMPFGNGTHSCPGNELAKLEMLVLFHHLATKYRWSTSKSESGVQFGPFALPLNGLPMSFTRKNTEQE", "length": 471, "molWeight": 52920, "crc64": "24D4FB1BC5A62BE9", "md5": "FEA111C2D9FE4AC50EE7B71F16B24F2E"}}
{"primaryAccession": "Q06244", "text": "This is 21S rRNA pseudouridine(2819) synthase protein, from Baker's yeast, contains 254 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06244", "organism_name": "Baker's yeast", "protein_name": "21S rRNA pseudouridine(2819) synthase", "length": 254, "firstPublicDate": "2005-11-08", "FUNCTION": "Pseudouridylate synthase responsible for the pseudouridine-2819 formation in mitochondrial 21S rRNA, May modulate the efficiency or the fidelity of the mitochondrial translation machinery", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the pseudouridine synthase RluA family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSLKKQIPIIFENTHYFIVNKPPGIPSQPPDCRTWGRTHPNLDPTPLLERFKAIYYSHREVELCRTVHRLDHCVTGGMLIAKTKDGSVKFSRFLQKGGNNGYKLQRKYVAIVESSGRFNKPNNYEIKYGPKYNFLISHGGREITKFKEVDENCIVLQLVTGKKHQIRNHVSQILNQPILNDKRHGSTVNFPELFNDQIALHSACIITKIGLQTKTHLIPMEHNNTGQLWSRKYVNEEGEFTLPIKEVLLENWDQ", "length": 254, "molWeight": 29359, "crc64": "7404383DCD726369", "md5": "561122FA0352CD2AE579450ECE4519C2"}}
{"primaryAccession": "Q06328", "text": "This is Probable vacuolar amino acid transporter YPQ2 protein, from Baker's yeast, contains 317 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06328", "organism_name": "Baker's yeast", "protein_name": "Probable vacuolar amino acid transporter YPQ2", "length": 317, "firstPublicDate": "2006-10-17", "FUNCTION": "May function as an amino acid transporter mediating the export of cationic amino acids from the vacuole", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the laat-1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSCSNGIWPTVSNLCGSLSFFTSVISLFPQIIETYRDKSVDGLSPYFLLAWLCGDITSLIGAKLTGQLLFQILLAIYFLLNDSFVCGQYYYYGVLHENKLATVGHEPKPLLPELVENGELLREEEDMIQGGSSAESPRSSRRRSAITAALAIAHTISTASAYPLNVGSTQSQVGPPGDGKNSQLGTILSWIGASFYVGARIPQLIKNYNRKSTDGLSPFLFATTLLCNITYNLSIFTSCRFLDNQNKREFIVNELPFIFGSAGTIAFDLIYFYQYYILYATDMQLRELERELYSPEEDSAAQLVTERTSLLSGETQT", "length": 317, "molWeight": 35179, "crc64": "F6A41A2175E05C75", "md5": "DFC329F76C53E34A52902B3E79BFF3C3"}}
{"primaryAccession": "Q06349", "text": "This is Decapping and exoribonuclease protein 1 protein, from Baker's yeast, contains 442 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06349", "organism_name": "Baker's yeast", "protein_name": "Decapping and exoribonuclease protein 1", "length": 442, "firstPublicDate": "2006-10-17", "FUNCTION": "Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity), The NAD-cap is present at the 5'-end of some RNAs and snoRNAs, In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity), Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (PubMed:22961381), Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (PubMed:22961381), Also has 5'-3' exonuclease activity (PubMed:22961381)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the DXO/Dom3Z family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSTEQDAVLGLAKDLEGINLLTVPNLERGHQSKLCKEKTTSDSSSSRKPSQQRDNYRKRRPKLICIPYTSFLHTGMHNFLTKPPRDIFHESKEVALFTNGRAYTILRKDLIPNLKESIAELYESSLLEAKKRKVPYLGHDLFANIDEFVPMTISELDSVSPCFSYIENWILDNPGKDFKIGKKFTVVTTRHHIVDLTMHLFNRRNRQTSLIVTYMGAGLLSFCRNVKKDSQMSKEGIYSNDPNMKKICYSGFEFENWVTENSKVADLTGSKCPIFSLVESKLSEEIGLLIRCEMDAFNPVSETNTELKCFAPLSMHNSNHRRKLLKTWVQTGLLPNSDIMIGLRDSHSGQLLDIQWYSRDLLCKKFNHPGLPTNKKELNYNAQIAVEWCHYCIEAICKLVEANISDYSSTKPESFEIGIDTNNAIVITKLKTTPRNVELFGM", "length": 442, "molWeight": 50492, "crc64": "504F7C6AA40B50E4", "md5": "3CDB9775060AEE961814A70E65BB9A0B"}}
{"primaryAccession": "Q06707", "text": "This is SWR1-complex protein 7 protein, from Baker's yeast, contains 132 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06707", "organism_name": "Baker's yeast", "protein_name": "SWR1-complex protein 7", "length": 132, "firstPublicDate": "2005-08-30", "FUNCTION": "Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SWC7 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDCPSNVVLLLLQLVLQRQQTLAHRDKSVDLQTLLKDPVIDNDVLVEFKTHKLVQLYGPQYCRDISLRGLKTMVTDIFANGIPKNAQSSGNDQPVTVVDLANYYYMQRINELQNTELPQLKEALLTRLEHMI", "length": 132, "molWeight": 15121, "crc64": "92CCE2FF3DCE72F1", "md5": "9CFA37317669B96D519F96DDA9B6BDF9"}}
{"primaryAccession": "Q06709", "text": "This is Cytoplasmic 60S subunit biogenesis factor REH1 protein, from Baker's yeast, contains 432 amino acids, has 3 C2H2-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [6, 30], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [186, 209], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [237, 261], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q06709", "organism_name": "Baker's yeast", "protein_name": "Cytoplasmic 60S subunit biogenesis factor REH1", "length": 432, "firstPublicDate": "2006-12-12", "FUNCTION": "Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit, May act redundantly with REI1 to directly promote a stabilizing structural rearrangement in cytoplasmic 60S subunit maturation independent on the REI1-specific ARX1 recycling", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the REI1 family", "domain_description": {"C2H2-type Zinc finger": 3}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSTFFTCNCCVIQFKTSDLQRYHMKTEWHRYNLKRRIANLPPIGAEQFAEKLQISEKEQAENQVDEFGFPVLKPVMNQSNALPQKQKKPIKSKRGRKVGTNLLKRKDRDIAKEKQNRSVSPSGSISSQLSNLTVGTENTNTDYGEDTVSEYGFTSDSNYEYATSDEELDIADKPSDKENEKITITECIYCGKDNKEVERNVKHMFSEHGLFIPERSYLIDLNGLLEFLIKMIVIDHNCLCCNFHGSGLESIRAHMASKRHCRLPYETKEERQLFAPFYDFTYDDHSISKNLQNDRAITSKLSSVYGAKNDEEDGEVDITLVSSENDINANYTTVSIDESGLELTLPTGARLGHRAGQRYYRQNLPSQPNPNESRRTITAADRRMVSGVTEKQYKKGMKKMQQLEKNAINTQIRREIKRVNFQTHYRDELLQ", "length": 432, "molWeight": 49690, "crc64": "1E4051797FD7D38A", "md5": "2621E4D8A79CDC5F191D43D4CCACBB50"}}
{"primaryAccession": "Q07500", "text": "This is External NADH-ubiquinone oxidoreductase 2, mitochondrial protein, from Baker's yeast, contains 545 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q07500", "organism_name": "Baker's yeast", "protein_name": "External NADH-ubiquinone oxidoreductase 2, mitochondrial", "length": 545, "firstPublicDate": "2006-12-12", "FUNCTION": "External NADH dehydrogenase required for optimum cellular growth with a number of nonfermentable carbon sources, including ethanol, With NDE1, performes the mitochondrial oxidation of cytosolic NADH under these growth conditions, Regulates the mitochondrial glycerol-3-phosphate dehydrogenase, GUT2, also involved in cytosolic NADH oxidation", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the NADH dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLPRLGFARTARSIHRFKMTQISKPFFHSTEVGKPGPQQKLSKSYTAVFKKWFVRGLKLTFYTTLAGTLYVSYELYKESNPPKQVPQSTAFANGLKKKELVILGTGWGAISLLKKLDTSLYNVTVVSPRSFFLFTPLLPSTPVGTIEMKSIVEPVRSIARRTPGEVHYIEAEALDVDPKAKKVMVQSVSEDEYFVSSLSYDYLVVSVGAKTTTFNIPGVYGNANFLKEIEDAQNIRMKLMKTIEQASSFPVNDPERKRLLTFVVVGGGPTGVEFAAELQDYINQDLRKWMPDLSKEMKVILIEALPNILNMFDKTLIKYAEDLFARDEIDLQVNTAVKVVEPTYIRTLQNGQTNTDIEYGMLVWATGNEPIDFSKTLMSRIPEQTNRRGLLINDKLELLGSENSIYAIGDCTAHTGFFPTAQVAHQEGEYLAKILDKKLQIEQLEWDMLNSTDETEVSRLQKEVNLRKSKLDKFNYKHMGALAYIGSETAIADLHMGDSSYQLKGMFAFLFWKSAYLAMCLSIRNRILIAMDWTKVYFLGRDSSV", "length": 545, "molWeight": 61659, "crc64": "291E81D0FC6D3FD7", "md5": "71DD1A6D5F11D48D79664B5B29BD4262"}}
{"primaryAccession": "Q07844", "text": "This is Ribosome biogenesis ATPase RIX7 protein, from Baker's yeast, contains 837 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q07844", "organism_name": "Baker's yeast", "protein_name": "Ribosome biogenesis ATPase RIX7", "length": 837, "firstPublicDate": "1997-11-01", "FUNCTION": "Involved in ribosome biogenesis, Seems to be required for restructuring nucleoplasmic 60S pre-ribosomal particles to make them competent for nuclear export", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the AAA ATPase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVKVKSKKNSLTSSLDNKIVDLIYRLLEEKTLDRKRSLRQESQGEEGENNEGEEDEDIFESMFFAKDLTAGEIFTFCLTKDLSLQRVKKVVLQKTIDRMLKDVIESELEEFGSYPGYNNEEEEKPSLEEELAKKNMMIERDTNEMNKRITSTWSKSGSVSESITETDDPKTEEVKKSKKRSKEGTCKVKRQKIKEDRSPPNSSLKSLGGMDDVVAQLMELIGLPILHPEIFLSTGVEPPRGVLLHGPPGCGKTSIANALAGELQVPFISISAPSVVSGMSGESEKKIRDLFDEARSLAPCLVFFDEIDAITPKRDGGAQREMERRIVAQLLTSMDELTMEKTNGKPVIIIGATNRPDSLDAALRRAGRFDREICLNVPNEVSRLHILKKMSDNLKIDGAIDFAKLAKLTPGFVGADLKALVTAAGTCAIKRIFQTYANIKSTPTTATDSSEDNMEIDETANGDESSLKNTANMIDPLPLSVVQQFIRNYPEPLSGEQLSLLSIKYEDFLKALPTIQPTAKREGFATVPDVTWANVGALQRVRLELNMAIVQPIKRPELYEKVGISAPGGVLLWGPPGCGKTLLAKAVANESRANFISIKGPELLNKYVGESERSIRQVFTRARASVPCVIFFDELDALVPRRDTSLSESSSRVVNTLLTELDGLNDRRGIFVIGATNRPDMIDPAMLRPGRLDKSLFIELPNTEEKLDIIKTLTKSHGTPLSSDVDFEEIIRNEKCNNFSGADLAALVRESSVLALKRKFFQSEEIQSVLDNDLDKEFEDLSVGVSGEEIIVTMSDFRSALRKIKPSVSDKDRLKYDRLNKKMGLTEEMKDAEEMKQ", "length": 837, "molWeight": 93069, "crc64": "133528B9D0987103", "md5": "C6DA352E0C2DDA247E548564FBAED3FF"}}
{"primaryAccession": "Q08287", "text": "This is 60S ribosome subunit biogenesis protein NOP8 protein, from Baker's yeast, contains 484 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08287", "organism_name": "Baker's yeast", "protein_name": "60S ribosome subunit biogenesis protein NOP8", "length": 484, "firstPublicDate": "2001-04-27", "FUNCTION": "Required for 60S ribosomal subunit synthesis, May be involved in assembly reactions occurring within late pre-ribosomal particles", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDSVIQKRIFVGNIFHNADDCYSELLDRFGKFGDCQDFQFEKHNHFAFIDIRFNDEADFNKLRKSFNNVKFKGNILKVDEAKPNWESTWAVQHAKDLKEDIILNAKMKKKNWQHYKKMENVAKSWKDHKEVIAGRMREAPRKRSQLRNITFRINVNGSLKVYKCYKTKLWGYERNKELNDLVYKFTNNFWKNGYNHIVDRLDYSRAVKTVRFKNGLKQLTVSKDENVCSGEMDSDENMSEEEKEKNNVILNDLLKDFDFDKPMTLNDSDEELLTEQRKGEEEEEEEEEKEVNAPEYENVNKTKDQSTLPQEKPEERKEQDEGDGQEDNEFIPTFTKEIGQGTISNTETLRNLFNPNEAEPVSQFKLIEDSDNDIDHAKDVDVNQLEEEVSKSSDTLGLTSAPVPHVSRDKDNKNFLFFPHLQSPFLVGQTQLSKVRAPGRETMLSNWDEEFWANRGNWTRDMRRKMKDALKHRKRKQSKSGLLL", "length": 484, "molWeight": 56966, "crc64": "30F291042433B208", "md5": "52CBB1441AC902E94B773B197F6D0753"}}
{"primaryAccession": "Q08742", "text": "This is Thiosulfate sulfurtransferase RDL2, mitochondrial protein, from Baker's yeast, contains 149 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08742", "organism_name": "Baker's yeast", "protein_name": "Thiosulfate sulfurtransferase RDL2, mitochondrial", "length": 149, "firstPublicDate": "2006-07-11", "FUNCTION": "Thiosulfate sulfurtransferase which catalyzes the transfer of sulfane sulfur from thiosulfate to cyanide", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFKHSTGILSRTVSARSPTLVLRTFTTKAPKIYTFDQVRNLVEHPNDKKLLVDVREPKEVKDYKMPTTINIPVNSAPGALGLPEKEFHKVFQFAKPPHDKELIFLCAKGVRAKTAEELARSYGYENTGIYPGSITEWLAKGGADVKPKK", "length": 149, "molWeight": 16697, "crc64": "8BF91B05233CB81F", "md5": "2B1905FFD44D82E865104A0626BA0098"}}
{"primaryAccession": "Q08925", "text": "This is RNA-binding protein MRN1 protein, from Baker's yeast, contains 612 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08925", "organism_name": "Baker's yeast", "protein_name": "RNA-binding protein MRN1", "length": 612, "firstPublicDate": "2000-05-30", "FUNCTION": "RNA-binding protein that binds specific categories of mRNAs, including those that contain upstream open reading frames (uORFs) and internal ribosome entry sites (IRES), Probably involved in translational regulation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVVSYNNNNNNNNNNNNNNISNNNNNNNMFPPFPSSDDFAMYQQSSSSGPYQETYASGPQNFGDAVYPMNGNFTLLPSDFTREPNDSFFYENDGIFDYQRIQQQPTQFQTKQRNDSQQQRFSQEQNFEIDNEVVHNNNRYYEYERSSNEVSPFDDENPNVLSDGMSPTIMATATAVTNANAPLPVNAQANNPLNFTSAPSRTVYLGNVPPNLSVKELLDHVRSGVVEDVKIIPEKMCAFVSFIDESAALLFHSDAILKRLNIGDRDIKIGWGKPTRIDPIVAARISTDGATRNVYIGRMTIEGEESHLSEEQLRVDLEEYGEIDCIKIIKEKGIAFIHFASILNAIKVVTNLPIRNPYYQNKRIFYGKDRCAFITKTQQHNAAQFLGVQPGMEHMIEFSDREFISNALLQQSAAAAAIATSAGGPNNLGNRTVYLGSLPKDVKIEEICNAVRGGLLQSIKLLNDRYVCFVTFIDPTAAAQFYAMSSLYGFTVQKKRCKVGWGKHSGPLPNALALAVSNGASRNVYVGNIDFVGDSLRDERVFTESNLRHIFQQYGEVEQINFLPEKNCCFINYTNISNAILALDKIKSNPYFKDLKINFGKDRCGNVPHQSR", "length": 612, "molWeight": 68664, "crc64": "A1B2EB381C0BBC8E", "md5": "513535279F9E24567B324AD302C3101F"}}
{"primaryAccession": "Q09377", "text": "This is Protein lin-56 protein, from Caenorhabditis elegans, contains 322 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09377", "organism_name": "Caenorhabditis elegans", "protein_name": "Protein lin-56", "length": 322, "firstPublicDate": "1995-11-01", "FUNCTION": "Required for translation, stability and/or localization of lin-15a", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDHHAMYRTAEFNKTTVRLLAEFIEKTGQNATIVNMDSFLEFFAYLNPTAPIPTVPEIEKQLLLKSPIRCIVCGMETESDSAVTLSIDNASIILTATVIGYCRDPSDAVNQIRKESLRACTKHFNSIFHVIFEGLQIENTYCAHHAKYSLANRWCKVYTMIRSSLGEQFTKFDVRNFKSILQSFLDTFGEIDDDKKDKESSHFDECFEEMDSENVEIKMESPQEEAAEKSKFSENLVEVKLEPIETHELDKTISDFSSSDIIDSSQKLQQNGFPEKVEQMDKYSNKLKDEASDKKYEKPGKKDYVEEEGYWAPITDSEDDEA", "length": 322, "molWeight": 36927, "crc64": "BC4B948D0416F2DA", "md5": "E21C610834CD81F0AA335325AFCC0C7E"}}
{"primaryAccession": "Q09712", "text": "This is GPI mannosyltransferase 2 protein, from Fission yeast, contains 464 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09712", "organism_name": "Fission yeast", "protein_name": "GPI mannosyltransferase 2", "length": 464, "firstPublicDate": "1995-11-01", "FUNCTION": "Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis, Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the PIGV family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MYYIGHPSYYRKHIEHVCFQHSGILKKRNYQKNQKKYIMKLNESAMKNAEKKSNSYLAIRMTRSGYNYFKGICVCTFLLSTILYLGIAVIMSHLCVFDDTAMLYLRQNRSRLAESNIFRTLFISWIRWDAIYFVDMAVNGSLFEQEWAFSSLWPKIISFLAFRSKDVVLLGIVSCFASIFFHAIACYALYLLTKSIFSNQKMTAYTVIFYCFSPSGIYMSVGYTESLFAAFSFLGLLLFIKKQQYPAAFLWSLATLIRSNGIFWCIFFGMPAIGTLKISLERLQLTFMQVSQLVGYGTKCLIILVPFFYNQYLGFKLFCPGVAWCNKSLPLIYPAVQEKYWNVGFLRYWTLNNIPNFLFALLSIIPILFALFYSISGSTLHSFRSIKSHLVLSALYLYIGCFHMHTQVLNRMSSALPLLYWSMAHATLYAKSRNLKAFGHCILFVWIVYTVIQAGLYGSFLPPA", "length": 464, "molWeight": 53608, "crc64": "FB1FF78DC133D14D", "md5": "94CFA0CC7111404A284D46CD97B25F58"}}
{"primaryAccession": "Q09778", "text": "This is Tuberous sclerosis 1 protein homolog protein, from Fission yeast, contains 899 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09778", "organism_name": "Fission yeast", "protein_name": "Tuberous sclerosis 1 protein homolog", "length": 899, "firstPublicDate": "1995-11-01", "FUNCTION": "Together with tsc2, required for uptake of various amino acids from the environment and for proper conjugation, Involved in induction of gene expression of permeases and genes required for meiosis upon nitrogen starvation, May act as a GTPase-activating protein (GAP) for the small GTPase rhb1", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPLQSLVKALWNVLHEEESEGYPDLTELIAEVESYQQRYPKQNPTNSQKIRHILDEIYEKTPFNNTRRRILWLAVLKTVIPLLILDRQAVGEWWDQIFFPFLNSPTQLKPVFSDLKSILFYILIFHDEDEWGGDLRRECAEETITRLVDLYVSKAIENLGDVESQEQRNQTIECLVNVLVHYGIQRPKELSSCFCHHFLNPPTRIPILSVMVEVIRRQGPRLYEIPQTGFYDLVLKCAEFDTSPILLSYALSFILMILSHICNSLDDSLYRLFCIYLRFSMIDPTSGFPSSTASGNWEVFHDFMSTYASTTTSQTDSSYNDVHDIVGSSQPDYLESLDYSQLFSILYALYPINFLEFLRDPKLYASKHNFQIRYSFNQELLSTKSDGLLGRHLAHSNFLKYTAETELTDKSRWTRLDSIAVVALCNSLNAVGIAESVMDPFGGKLPTTYEETSSATGLLAYPNESHDIASEPFSISWPQNPSISGSVHSATTFDKAQLSNTEDSYDNISHGTSYSEGVSSIHMVKGERGSNNLELTSESLSSTNDTIRRLQRDLLFLQNELRFEKFVRQQHLQNIGKLHREHILDMAVESERQKLLLTNKRYKAQIELLNSEIDKHRSESQAALNRRVKWENDFNNKIKALREEKKAWKSEESELKSSIESLISQLESIRNSQIDIAFSKNQLELKLQLYETKLKEYEQHLSCVNISKKQVSSSSDTSFGNTKMDSSMILSNSEAVSDEQERELIESEKHRMKLESENLHLQANIELLKKDLEAINVVYEAKIFDLEKRLSSEANAPELHNPVNLNYDAQLSKISEIKENYDELLTRYRELEGKFLESQAEVEELKNFQKPLVDTGSSIHSSPGLQQSKFIIRNDSLHPKVGPPRRQSTDTSRSTFRQY", "length": 899, "molWeight": 103435, "crc64": "03D7E9CC8866ECAB", "md5": "7E0465E8CB64B35EB4E760CE015B8152"}}
{"primaryAccession": "Q09868", "text": "This is RNA-binding post-transcriptional regulator cip2 protein, from Fission yeast, contains 576 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09868", "organism_name": "Fission yeast", "protein_name": "RNA-binding post-transcriptional regulator cip2", "length": 576, "firstPublicDate": "1996-02-01", "FUNCTION": "Regulates global gene expression after oxidative stress, Interacts and stabilizes mRNAs and may regulate their transition between different cytoplasmic components after oxidative stress", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAEGTSQRPLTPLSQAFLSTNTLSPASSPLTFHSEAASLRRKRSNFFPKLDELNGAQDEEMRGLNIPGGSGYLENRYGRDKFTFSDAAVNSAGMGGSGIFSHNNADDGLGDGSSTVLPSSLKQMLDPEISTANNPSAKPRRTRLQTAWKEATNSAGLSLRSASALDVLKNSGPATTSLLSSTTYPFDSLNAFNEPSHSHVPNSASSTALSRGMSNSVTLTAPPEPDEETIPTAIVIKNIPFSLKKEVLFKVFTALDIPRPYAFNYHFDNGVFRGLAFANFHSPEEAKTVVQVLNGYEITGRRLRVEWKRQLPPAERERVERGKQEKRAVEERKNQLKSPFSVANIGAGIDFDLNDPAILNVYSHILLFYYRSDNTNDLVFDSSTTQEERRVAALLASRLNLNHSVTGDGEAKQVVITMPSTHFTPANNSSANHSPLMAPNASTLNPSSLGASNLSQPSLANHLSSSGLFDNGLFSSGGLSSNFSSLRRPAPSMHLADSIRSLRGLNDSKAFSDIRSMPATPLELATPFANLNVSSPLDRNATNSSNTLNGSAMNDYFASLTPSNTGAIGSRTFTKN", "length": 576, "molWeight": 62069, "crc64": "41FBD27201EE7D07", "md5": "D1E599B4468A1E47EC50FD40F79C44AA"}}
{"primaryAccession": "Q0WMY5", "text": "This is Pentatricopeptide repeat-containing protein At5g04810, chloroplastic protein, from Mouse-ear cress, contains 952 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0WMY5", "organism_name": "Mouse-ear cress", "protein_name": "Pentatricopeptide repeat-containing protein At5g04810, chloroplastic", "length": 952, "firstPublicDate": "2009-02-10", "FUNCTION": "May play a role in the plastid ribosome biogenesis", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the PPR family, P subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDNGGSVLSLSAPHFPYSATILRRHSPVASISFSLKQPPPQPPEPPESPPDLRRPEKSIGSSSSSSSPSPIPSPKTPLKINPLKGLTNRSSVSPLVQSEVSSKVSSFGSSLASKLRLSSKLSPPPPPPPPPPVEETTQFRDEFRSDTKPPEEETRNPQQEFRQEGKIFVGNLPTWIKKPEFEEFFRQFGPIENVILIKGHHEVEKNAGFGFIIYAAEKSAMKAVEFDGVEFHGRILTVKLDDGKRLKTKAEQRVRWVEEGEEDTKMSNKSSWHQEREGSRKSLQRILDTNGDNWQAVISAFEKISKPSRTEFGLMVKFYGRRGDMHRARETFERMRARGITPTSRIYTSLIHAYAVGRDMDEALSCVRKMKEEGIEMSLVTYSVIVGGFSKAGHAEAADYWFDEAKRIHKTLNASIYGKIIYAHCQTCNMERAEALVREMEEEGIDAPIAIYHTMMDGYTMVADEKKGLVVFKRLKECGFTPTVVTYGCLINLYTKVGKISKALEVSRVMKEEGVKHNLKTYSMMINGFVKLKDWANAFAVFEDMVKEGMKPDVILYNNIISAFCGMGNMDRAIQTVKEMQKLRHRPTTRTFMPIIHGYAKSGDMRRSLEVFDMMRRCGCVPTVHTFNGLINGLVEKRQMEKAVEILDEMTLAGVSANEHTYTKIMQGYASVGDTGKAFEYFTRLQNEGLDVDIFTYEALLKACCKSGRMQSALAVTKEMSARNIPRNSFVYNILIDGWARRGDVWEAADLIQQMKKEGVKPDIHTYTSFISACSKAGDMNRATQTIEEMEALGVKPNIKTYTTLIKGWARASLPEKALSCYEEMKAMGIKPDKAVYHCLLTSLLSRASIAEAYIYSGVMTICKEMVEAGLIVDMGTAVHWSKCLCKIEASGGELTETLQKTFPPDWSSHHHHHGFLDQVSDVDSDEDDVDGEDGEDDEDVNSVSDLLSPYK", "length": 952, "molWeight": 106740, "crc64": "6D59E546E657B74D", "md5": "745258F46F98A3F3DB9EF9F9D21F11B1"}}
{"primaryAccession": "Q0WMZ5", "text": "This is Outer envelope pore protein 16-2, chloroplastic protein, from Mouse-ear cress, contains 178 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0WMZ5", "organism_name": "Mouse-ear cress", "protein_name": "Outer envelope pore protein 16-2, chloroplastic", "length": 178, "firstPublicDate": "2012-02-22", "FUNCTION": "Voltage-dependent high-conductance channel with a slight cation-selectivity; selective for amino acids but excludes triosephosphates or uncharged sugars (By similarity), Non-essential amino acid-selective channel protein and translocation pore for NADPH:protochlorophyllide oxidoreductase A (PORA) and possibly PORB", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the Tim17/Tim22/Tim23 family, Plastid outer envelope porin OEP16 (TC 1,B,30) subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEKSGGRIVMDEIRSFEKAHLFDLGHPLLNRIADSFVKAAGVGALQAVSREAYFTVVDGAGFDSNNVGPPSEITGNKKHRFPNLRGESSKSLDALVKNTGKESLQWGLAAGLYSGITYGMTEVRGGAHDWRNSAVAGALTGAAMAMTTSERTSHEQVVQSALTGAAISTAANLLSSVF", "length": 178, "molWeight": 18714, "crc64": "17CDF6186A41FE82", "md5": "1E5C66E94B01CF8EC6DBE27F148A647F"}}
{"primaryAccession": "Q0WTP1", "text": "This is AUGMIN subunit 7 protein, from Mouse-ear cress, contains 329 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0WTP1", "organism_name": "Mouse-ear cress", "protein_name": "AUGMIN subunit 7", "length": 329, "firstPublicDate": "2015-10-14", "FUNCTION": "Contributes to the assembly of the acentrosomal spindle and phragmoplast microtubule arrays as part of the augmin complex, Regulates the association of gamma-tubulin with the spindle and phragmoplast microtubules", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAKQMEEIQKKLRLLSYPRANAPAQSLLFAGMERYALLEWLFFKLLGDKSPFSQQNLQGDAGVRDEETVRIQYLAEIAKFLGITPTVDIEAIQGHGTYEDRMEMLRNIVDLVEASLFSDNQEWSIDEQVAKDIQLIDAIAERQSLIFSEECKLFPADVQIQSIYPLPDVSELETKLSEQAKILSNLQQKVDDLAAKHAYNPDEEYTEVESQLRARLESFLETARAFNTIYTKEIRPWTHMMEVPQLHGFGPAANRLLEAYNMLLKFLGNLKNLRDSHAALSIGSSGTVAGEPSSVTRIVSDCEAALTVLNRDLGILSASIAREQGERL", "length": 329, "molWeight": 37009, "crc64": "CAA1602ECAB4DA97", "md5": "4FBEE34FBC09491F465385EA9EF4B9FC"}}
{"primaryAccession": "Q10269", "text": "This is Probable sterol O-acyltransferase 1 protein, from Fission yeast, contains 537 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10269", "organism_name": "Fission yeast", "protein_name": "Probable sterol O-acyltransferase 1", "length": 537, "firstPublicDate": "1996-10-01", "FUNCTION": "Sterol O-acyltransferase that catalyzes the formation of stery esters", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the membrane-bound acyltransferase family, Sterol o-acyltransferase subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTDTPRILITPSPLSDISTTINKPNVHPSMSLLKALPECRLVVKSKGDKNNANVVEFPLDRHKQLLIAGKVYHDYKFKPRKSIFDRVTDPNYFAKSEFRGFYVLFWLSMAAWVLQLYARSYWQRDTLLGLPLARQVFRQFFVLFSSDFLMICLSFFSYGLQVCIEKNMIRWANLGYTIQTLWQGFYMVLAVYWVKHRDFPIVQCVFFTLHCAVLIMKQFSYSHHMGYISEIRILHNEYEKLLKFVRECLNSTEKDEKYTFELTFPNKPAETISTLQAEEIVALTAKYLSRQMRSEVGNVVYPDNINFFNYVDYLLVPSLVYSMEFPRVAHFRWHYMAFKAGSTFGLLALTLALVDWYFVPSAVAVKDLDFIGKLRIAPLLMNKIMFPAIILYLIMFYLIFDCILNAFAEITKFADRGFYGAWWNTVTWDEFSREWNKPVHVFLMRHVYHSSISGFKLKKSHAVLLTFLISALVHEFVMLLATGKFRCYILTFQLLQIPLYDLQQMFAFKKRDILGNVFFWIGMFTGPSFLCILYIVF", "length": 537, "molWeight": 63098, "crc64": "41DBA79402B67A28", "md5": "0EBCC6A79E72580B7987EA7263D1B40C"}}
{"primaryAccession": "Q10430", "text": "This is Kinetochore protein spc25 protein, from Fission yeast, contains 238 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10430", "organism_name": "Fission yeast", "protein_name": "Kinetochore protein spc25", "length": 238, "firstPublicDate": "1996-10-01", "FUNCTION": "Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle, Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SPC25 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSLANFPTIELDYDSLKSKISNFNSIFDRFLQEERKKLLNNKNEYLRQLSEINEAQKKAEKSLEQTEARKQNFTELLEKEHEEQAITEQEIFSFQEKLDAMLKRKQKLSEELDHYRAIISSKRELRAQEMEAKRKQDSYNNPELKFWEDYLGLKMEGVHDEVIRFIFTNIDEKDWNKQFSFQINLAERDYKVVHCHPPLPHVDDLVNKVNRTRDFYQFLKDMRKGFRELHRKDLSQLI", "length": 238, "molWeight": 28811, "crc64": "7351F2E8CDFC2659", "md5": "7626E53972792F6C6B6E68B0C1E5E8CF"}}
{"primaryAccession": "Q12008", "text": "This is Phosphoglycerate mutase 2 protein, from Baker's yeast, contains 311 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12008", "organism_name": "Baker's yeast", "protein_name": "Phosphoglycerate mutase 2", "length": 311, "firstPublicDate": "1997-11-01", "FUNCTION": "Could be non-functional", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the phosphoglycerate mutase family, BPG-dependent PGAM subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTASTPSNVMTLFLLRHGQSELNHENIFCGWIDAKLTEKGKEQARHSAELIEQYCKANNLRLPQIGYTSRLIRTQQTIETMCEEFKLKPQLQVVYDFNKIKLGDEFGSDDKDNMKIPILQTWRLNERHYGSWQGQRKPNVLKEYGKDKYMFIRRDYEGKPPPVDLDREMIQQENEKGSSTGYEFKEPNRQIKYELECSNHDIVLPDSESLREVVYRLNPFLQNVILKLANQYDESSCLIVGHGSSVRSLLKILEGISDDDIKNVDIPNGIPLVVELDKNNGLKFIRKFYLDPESAKINAEKVRNEGFIKNP", "length": 311, "molWeight": 36073, "crc64": "1E53ECAAF06C932C", "md5": "D987BE4198F81DC97181982C9FF85CCA"}}
{"primaryAccession": "Q12010", "text": "This is Probable vacuolar amino acid transporter YPQ1 protein, from Baker's yeast, contains 308 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12010", "organism_name": "Baker's yeast", "protein_name": "Probable vacuolar amino acid transporter YPQ1", "length": 308, "firstPublicDate": "2006-05-16", "FUNCTION": "May function as an amino acid transporter mediating the export of cationic amino acids from the vacuole", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the laat-1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQLVPLELNRSTLSGISGSISISCWIIVFVPQIYENFYRKSSDGLSLLFVVLWLAGDVFNLMGAVMQHLLSTMIILAAYYTVADIILLGQCLWYDNEEKPAVDPIHLSPANPINENVLHDVFNEQQPLLNSQGQPNRIDEEMAAPSSDGNAGDDNLREVNSRNLIKDIFIVSGVVFVGFISWYVTYCVNYTQPPPVEDPSLPVPELQINWMAQIFGYLSALLYLGSRIPQILLNFKRKSCEGISFLFFLFACLGNTTFIFSVIVISLDWKYLIMNASWLVGSIGTLFMDFVIFSQFFIYKRNKKFILN", "length": 308, "molWeight": 34873, "crc64": "38EB1645FA034812", "md5": "95BFD003D543E2C28C6EAE735CEB4059"}}
{"primaryAccession": "Q12035", "text": "This is rRNA-processing protein FCF2 protein, from Baker's yeast, contains 217 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12035", "organism_name": "Baker's yeast", "protein_name": "rRNA-processing protein FCF2", "length": 217, "firstPublicDate": "2006-10-17", "FUNCTION": "Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly, Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the FCF2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDQSVEDLFGALRDASASLEVKNSAKEQVSLQQEDVLQIGNNDDEVEIESKFQEIETNLKKLPKLETGFDALANKKKKKNVLPSVETEDKRKPNKSDKNDNDWFTLPKPDDNMRREVQRDLLLIKHRAALDPKRHYKKQRWEVPERFAIGTIIEDKSEFYSSRMNRKERKSTILETLMGDEASNKYFKRKYNEIQEKSTSGRKAHYKKMKEMRKKRR", "length": 217, "molWeight": 25636, "crc64": "0F79F36CBBA3B12C", "md5": "7AD94DB82636057EF24DD56813855B41"}}
{"primaryAccession": "Q12072", "text": "This is ISWI one complex protein 2 protein, from Baker's yeast, contains 812 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12072", "organism_name": "Baker's yeast", "protein_name": "ISWI one complex protein 2", "length": 812, "firstPublicDate": "2006-06-27", "FUNCTION": "Functions as component of the ISW1B complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA, The ISW1B complex acts within coding regions to control the amount of RNA polymerase II released into productive elongation and to coordinate elongation with termination and pre-mRNA processing", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRTKRTRGTRNVGASMPAGAANADSEDWKEYVSEDIIAQLNKHQLPYSEILDEKIADLANHWHFQYVMAWLSNVCESYTTTTFNTDQYGGSSTKCLWKNIKFDEGVFVTDVFSKIDGKDSNYYNDEVDVDEGSQNLYDRIRLQLLHQLAGNKSGQLKDWNVIVNHHLQNSSAYSDLVTDLPFLELEIARQFDIIYSIIKLIEMKNMIFKNYLANNLHLFTFSEVILDDDNSGGEEMKSLFALPNVGVLVKKTIHRVKEGSSSQVSQTLNIPIKLQNCTIKESDPDIPDSVELIHLEYSHDIDAYLQSITIDYDVITTNWGSMLEYWSENKSSKAIDEFITNLIPVYAEHRLYSAKLLANREKERAIAELMTRRKRSSRLVAKEEENKKKDLESEWFEKLDEREQFIRHRNKLVSKEIKKIKDLLWNQLWQLYDQDYRDEKLTRRNELKDRSGSGTPFFETSLGREEDNPLNEIDIGVLDHGPNFQSSIIPVEPPIPGTVGPLQTGDVPELPSDFCITKEELDELANYGIFTPQQEPDNQDSVFQCPGEPELAPMIITEDTETDLFNNRPLICCDHCYRWQHWECQPPKIIELISSTTKSPQHTLSQRDFGVIIMGNSHGNRRSSRRPQSTLEPSTKSSRPTDKRKPLSECSTFICAWCIRDLELELRNIFVPELKIIRAKQRKQQEDRERRKKMKEEKKRLEELAKKRELTESVSPPVFNNAFANMSSSTTPSIAAYEKTNPAINPAPNVNAAHPIITYSQQTGSKTVPQAPQAPQTSQASIQPQQQQQQQQQQQPLHPKEQNFHFQFPPTN", "length": 812, "molWeight": 93446, "crc64": "632AD02AA8229D87", "md5": "BF2674605C2F656A3FBEF3902435C85A"}}
{"primaryAccession": "Q12102", "text": "This is Cleavage factor two protein 2 protein, from Baker's yeast, contains 859 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12102", "organism_name": "Baker's yeast", "protein_name": "Cleavage factor two protein 2", "length": 859, "firstPublicDate": "2006-01-10", "FUNCTION": "RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB, May be involved in poly(A)-site recognition, May be involved in the association of the CPF, CPFIA and RNA polymerase II complexes", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTYKYNCCDDGSGTTVGSVVRFDNVTLLIDPGWNPSKVSYEQCIKYWEKVIPEIDVIILSQPTIECLGAHSLLYYNFTSHFISRIQVYATLPVINLGRVSTIDSYASAGVIGPYDTNKLDLEDIEISFDHIVPLKYSQLVDLRSRYDGLTLLAYNAGVCPGGSIWCISTYSEKLVYAKRWNHTRDNILNAASILDATGKPLSTLMRPSAIITTLDRFGSSQPFKKRSKIFKDTLKKGLSSDGSVIIPVDMSGKFLDLFTQVHELLFESTKINAHTQVPVLILSYARGRTLTYAKSMLEWLSPSLLKTWENRNNTSPFEIGSRIKIIAPNELSKYPGSKICFVSEVGALINEVIIKVGNSEKTTLILTKPSFECASSLDKILEIVEQDERNWKTFPEDGKSFLCDNYISIDTIKEEPLSKEETEAFKVQLKEKKRDRNKKILLVKRESKKLANGNAIIDDTNGERAMRNQDILVENVNGVPPIDHIMGGDEDDDEEEENDNLLNLLKDNSEKSAAKKNTEVPVDIIIQPSAASKHKMFPFNPAKIKKDDYGTVVDFTMFLPDDSDNVNQNSRKRPLKDGAKTTSPVNEEDNKNEEEDGYNMSDPISKRSKHRASRYSGFSGTGEAENFDNLDYLKIDKTLSKRTISTVNVQLKCSVVILNLQSLVDQRSASIIWPSLKSRKIVLSAPKQIQNEEITAKLIKKNIEVVNMPLNKIVEFSTTIKTLDISIDSNLDNLLKWQRISDSYTVATVVGRLVKESLPQVNNHQKTASRSKLVLKPLHGSSRSHKTGALSIGDVRLAQLKKLLTEKNYIAEFKGEGTLVINEKVAVRKINDAETIIDGTPSELFDTVKKLVTDMLAKI", "length": 859, "molWeight": 96254, "crc64": "44997871ECE6225F", "md5": "4A07AAAD5EE136EFDF384327EC2CA989"}}
{"primaryAccession": "Q12204", "text": "This is Probable phospholipase YOR022C, mitochondrial protein, from Baker's yeast, contains 715 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12204", "organism_name": "Baker's yeast", "protein_name": "Probable phospholipase YOR022C, mitochondrial", "length": 715, "firstPublicDate": "2006-05-30", "FUNCTION": "Probable phospholipase that hydrolyzes phosphatidic acid", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the PA-PLA1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRFTHRGLPSSTRFRNIFVRLNHIYVPWFYAIDVPNSKPYLPTYQTLHSPKKFKPFSVDDSNRLEKASKRQERRPVLVNEDYLFKVDLSHMELSPTYWEGPTYQVRRGVWFDSSNQPLSSDLTSEIEGLYKQLKFDDSNDDPTTTPPAESQDIFRLKGKYPVDKENEGEQKNGSSNKDENESTFKFILFANKQTAFLLSDLDGGKLQLAFLRSNLAQSLPINATMITRSYKYSSSATTKQTSTSFKAAKTPQTEVADGSNSSKSRSIETKLEKKVSNLFNLSDFLQLFNGNASKDQDDAQSLEKQMETDYNNADNSQGANASSKIEDGKNSGASDRQIRSNRRDVDNLILCVHGIGQTLGKKYEYVNFAHTVNLLRSNMKKIYNNSEKLQSLNTAPDYKSNCNVQVLPITWRHSISFQTDAKEENIENPDLPTLSQVTVNGVLPLRKLLADGLLDILLYVEPYYQDMILQQVTSQLNKTYRIFKEFNPEFDGKVHLVGHSLGSMILFDILSKQKKYELEFQVDNLFFIGSPIGLLKLIQRTKIGDRPEFPNDLERKLTVQRPQCKDIYNVYHVCDPISYRMEPLVSKEMAHYEQTYLPHCSEAYGLTSKVLEFGENIWKDLPGTDENNLQSKKTSPEKKEVKLSENLTRMLTGLNYTGRLDYAMSPSLLEVDFISAIKSHVSYFEEPDIAAFILKEILSKHENASEIYVKRKTG", "length": 715, "molWeight": 81769, "crc64": "DE3982A606E4BD9C", "md5": "98C797A5B4A34F5097FC0E1360D31F30"}}
{"primaryAccession": "Q12270", "text": "This is Rhomboid protein 2 protein, from Baker's yeast, contains 262 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12270", "organism_name": "Baker's yeast", "protein_name": "Rhomboid protein 2", "length": 262, "firstPublicDate": "2005-11-08", "FUNCTION": "Probable serine protease", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the peptidase S54 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNWKSYVFPGGHPPAALTTGLVVFLTAIYLLSFIFALREDLSLAPESLFKLQMSRLSLYPLIHLSLPHLLFNVLAIWAPLNLFEETHGTVYTGVFLNLSALFAGILYCLLGKLLYPEALVAGASGWCFTLFAYYSFKESQIRPRTRIFRTDYSIPTLYTPLVLLVAIAVVIPGSSFWGHFFGLCVGYAIGYKESWFNKITPPGWIITKIEKSLDGLIRLIPWGIKYYRDEDIDRTKDYEPLMSTETPLPLHNDNSGTVLGTA", "length": 262, "molWeight": 29500, "crc64": "3A436E3FEAB7FD35", "md5": "FBDA42B90AF688168A44E04638CC794C"}}
{"primaryAccession": "Q12359", "text": "This is Ammonia transport outward protein 3 protein, from Baker's yeast, contains 275 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12359", "organism_name": "Baker's yeast", "protein_name": "Ammonia transport outward protein 3", "length": 275, "firstPublicDate": "1998-07-15", "FUNCTION": "Transporter protein required for ammonia export, Induced in rho(0) cells, probably to eliminate the excess ammonia that arises because of a potential defect in ammonia assimilation in those cells", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the acetate uptake transporter (AceTr) (TC 2,A,96) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTSSASSPQDLEKGVNTLENIETLPQQGSIAGVSQGFPNIQEIYSDRDFITLGSSTYRRRDLLNALDRGDGEEGNCAKYTPHQFANPVPLGLASFSLSCLVLSLINANVRGVTDGKWALSLFMFFGGAIELFAGLLCFVIGDTYAMTVFSSFGGFWICYGYGLTDTDNLVSGYTDPTMLNNVIGFFLAGWTVFTFLMLMCTLKSTWGLFLLLTFLDLTFLLLCIGTFIDNNNLKMAGGYFGILSSCCGWYSLYCSVVSPSNSYLAFRAHTMPNAP", "length": 275, "molWeight": 30028, "crc64": "CB4E91128403C6CC", "md5": "B3B916AC0D17597BA8F5CB3FD213DA3D"}}
{"primaryAccession": "Q12427", "text": "This is Protein STB3 protein, from Baker's yeast, contains 513 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12427", "organism_name": "Baker's yeast", "protein_name": "Protein STB3", "length": 513, "firstPublicDate": "2005-11-22", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the STB3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSENQKEVSPPQAISVKSEASSSIFSKPISTSSPAGLAAAQRVTPGKLSTLLLEMGPLAIRHITQTLCLDIPCFKDLSSSKQRRLIMSAMESGDKEKSVVFEKIGWGQWSAKRVDPANFDKELEATNFANAKVKDLISQESQRRKSNNSNSNSGGKVEMPMKVEHNITNIDGATTPPTAVASTTIPVNIKRSKSPLAAANVVYIDENALASEDEDEEFDEDDHHLHYQNKSRNSSNNFGKSSNGDPYSFGRRRSQVVFADSTPENIEHEIIAQKIRPLLRNRRRSSIKPHTPFISKLNTHQDSSYLSPNTTSTTTPSNNNSNSNQAKIDLEKLTATSEPTSRRASRLSVSKESSIRSTLFPNKNYLIVTTNPNSKATSVSTSPKLEEQMNVSSNPIVLSDKEKHRVASQHLNGESSPQLVPHSHHQPHSDTDEEDWESIGAASLRNNSLAPNIDSVASSTNGVVSPKPTNPSFTNSQNGDIEPPLQHDQQKHEQQPRNGEDNSAAFLLMSLKS", "length": 513, "molWeight": 56264, "crc64": "442B5633334B938F", "md5": "FA8260E2F8D1848DEFC6C35CCA7E4FAD"}}
{"primaryAccession": "Q12487", "text": "This is Large ribosomal subunit protein uL13m protein, from Baker's yeast, contains 163 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12487", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein uL13m", "length": 163, "firstPublicDate": "2002-10-10", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSQKIGHSGLAFARLWHHVDVARDKRTLGRLASAIAITLIGRHKPVYHPSQDCGDYVVVTNCQKIRVTGKKFEQKTYWSHSGRPGQLKLQTMNKVVADKGFGEILKKAVSGMLPKNKLRKQRLDRLKVFDGSENPYKQNITAFAHEQSSIPEPLKESIFNQLK", "length": 163, "molWeight": 18463, "crc64": "5FD27E5A965F6315", "md5": "46D3D34063FDA980E96F5D52D4F79195"}}
{"primaryAccession": "Q18409", "text": "This is Probable splicing factor, arginine/serine-rich 6 protein, from Caenorhabditis elegans, contains 179 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q18409", "organism_name": "Caenorhabditis elegans", "protein_name": "Probable splicing factor, arginine/serine-rich 6", "length": 179, "firstPublicDate": "2004-12-21", "FUNCTION": "Plays a functionally redundant role in shifting germ cell sexual differentiation in hermaprodites, Required for the development of somatic gonad structures and for progression from larval stage to adulthood", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the splicing factor SR family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDAKVYVGGLPSDATSQELEEIFDRFGRIRKVWVARRPPGFAFVEYDDVRDAEDAVRALDGSRICGVRARVELSTGQRRGGGGRGGGFGGRGGGGRDRSPYRGDRGRSRSRSRDRGRDRSRDRSRDRSRDRSRDRSRERSRERERTRSRSRSPQERDRSHSKSRSRSRSRSRSRSASPH", "length": 179, "molWeight": 20481, "crc64": "7E5E09ECE00C3E7E", "md5": "E4BABEF9F2047D1351CDAEE319F51910"}}
{"primaryAccession": "Q1A3R1", "text": "This is Mu-conotoxin Lt5d protein, from Lettered cone, contains 62 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q1A3R1", "organism_name": "Lettered cone", "protein_name": "Mu-conotoxin Lt5d", "length": 62, "firstPublicDate": "2008-01-15", "FUNCTION": "Mu-conotoxins block voltage-gated sodium channels (Nav), This toxin inhibits tetrodotoxin(TTX)-sensitive sodium channels, but does not affect TTX-resistant sodium channels, Reduces the amplitude of currents without changing the activation and inactivation kinetics of currents", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the conotoxin T superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRCLPVFIILLLLIPSAPSVDAQPTTKDDVPLASLHDNAKRALQMFWNKRDCCPAKLLCCNP", "length": 62, "molWeight": 6907, "crc64": "D9F0575D4EAD468E", "md5": "BE20FA9D1A2F27494CAFD1620862D4B6"}}
{"primaryAccession": "Q1ECF5", "text": "This is LIM domain-containing protein PLIM2b protein, from Mouse-ear cress, contains 205 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q1ECF5", "organism_name": "Mouse-ear cress", "protein_name": "LIM domain-containing protein PLIM2b", "length": 205, "firstPublicDate": "2014-10-29", "FUNCTION": "Binds to actin filaments and promotes cross-linking into thick bundles, Has an actin-stabilizing activity, The actin regulatory activities are inhibited by pH > 6,8 but are [Ca(2+)] independent", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSFTGTLDKCNVCDKTVYVVDMLSIEGMPYHKSCFRCTHCKGTLQMSNYSSMDGVLYCKTHFEQLFKESGNFSKNFQPGKTEKPELTRTPSKISSIFCGTQDKCAACEKTVYPLEKIQMEGECFHKTCFRCAHGGCTLTHSSYASLDSVLYCRHHFNQLFMEKGNYAHVLQAANHRRTASGNTLPPEPTEDVAVEAKEENGVSES", "length": 205, "molWeight": 22989, "crc64": "4687089B0E5799BF", "md5": "25BF479F818193C95E8DBF00FFEA8B96"}}
{"primaryAccession": "Q1EJP5", "text": "This is Dermaseptin-H4 protein, from Orange-legged monkey tree frog, contains 73 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q1EJP5", "organism_name": "Orange-legged monkey tree frog", "protein_name": "Dermaseptin-H4", "length": 73, "firstPublicDate": "2006-09-05", "FUNCTION": "Has antibacterial activity against the Gram-negative bacteria E,coli ATCC 11775 (MIC=0,8 uM), and the Gram-positive bacteria S,aureus ATCC 12600 (MIC=0,4 uM) and M,luteus ATCC 49732 (MIC=0,8 uM), Does not inhibit the growth of the fungus C,albicans, Probably acts by disturbing membrane functions with its amphipathic structure", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Dermaseptin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFMKKSLFLVLFLGMVSLSICEEEKRENEDEAKQEDDEQSEMKRGLWSTIKNVGKEAAIAAGKAALGALGEQ", "length": 73, "molWeight": 8050, "crc64": "639CA5CCEEA16798", "md5": "1A95629037711503ECD19C9540D1D49A"}}
{"primaryAccession": "Q1K8F6", "text": "This is Amino-acid acetyltransferase, mitochondrial protein, from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), contains 712 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q1K8F6", "organism_name": "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "protein_name": "Amino-acid acetyltransferase, mitochondrial", "length": 712, "firstPublicDate": "2009-05-05", "FUNCTION": "N-acetylglutamate synthase involved in arginine biosynthesis", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the acetyltransferase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFVRTCRSSCNAWTNATSTTQAGSLLPPNAHRSVVLTLSLQACSARTHESLIRSFASTTSQSKRQEAEAEEKRQVSPRLGPSAPRSSYPSSAEARQKRDSDREFLISVLESSATKRDARGYLQTFGSSAALTSAGQKKPSTIGILGVPASVAGRPAFVQGTEKEISVKRNEAPHVAVVKLRAPQAWDDVLLEGVAKTLTRLRDLGLLSVIVLDCDDIKPNQASSWHETVTEQTDRLLRAIGQYGFPAAEVVDSGIWKSTENPQIPSSVPSNPLYVGFGKAFTTPLANGHILVVPPRAYSDASLQYSKADANDIVIALTTFFAGLQFGQQSSDYRQLAEKVSDGQSFRKALVDRVIVIDPLGGIPSHRQGHGTQVFINLEDEFKNIQDALYEKTQPTSAGTKDAGVSARATVHLENLRLAKSTLALLPSNASVVMTSPAEAANINVSRRNQLEAKPDGFAGEVKTRTWRNPLIHNLLTDRPIYSSSLPIGRIKPTHQDEEIALSRMPTTTLAKRGLPVTIFPDPRVNRWQPPQPGVPRLRLTDTCIDLPRLVHLINDSFGRKLNVEHYLDRVKDSLAGIIIAGEYEGGAILTWETPFGLDEETAYRKGRLVPYLDKFAVLRKSQGAGGVADIVFNAMVRDAFPDGVCWRSRKDNPVNKWYFERSRGVLKLPESNWAMFWTTPEAVSNDQMMRDYEDVCRNIAPSWADTTKPAD", "length": 712, "molWeight": 78280, "crc64": "C8F6F7494258F1C6", "md5": "96D9F29EC54106D7AB589EE5E5B72198"}}
{"primaryAccession": "Q2L4Q9", "text": "This is Serine protease 53 protein, from Human, contains 553 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q2L4Q9", "organism_name": "Human", "protein_name": "Serine protease 53", "length": 553, "firstPublicDate": "2008-02-05", "FUNCTION": "In vitro can degrade the fibrinogen alpha chain of as well as pro-urokinase-type plasminogen activator", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKWCWGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHTPLCLPQPAHRFPFGASCWATGWDQDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEPEPEAEPGSCLANISQPTSC", "length": 553, "molWeight": 58410, "crc64": "8464159A3E65AFA7", "md5": "0AE38AEC6819CA164BAB353888E01798"}}
{"primaryAccession": "Q2QX40", "text": "This is Zinc finger protein STAR3 protein, from Rice, contains 465 amino acids, has 1 C2H2-type Zinc finger, has 1 C2H2-type 2; atypical Zinc finger, has 1 C2H2-type 3; atypical Zinc finger, has 1 C2H2-type 4; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [229, 251], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [281, 314], "description": "C2H2-type 2; atypical", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 2; atypical Zinc finger"}, {"location": [319, 342], "description": "C2H2-type 3; atypical", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 3; atypical Zinc finger"}, {"location": [347, 371], "description": "C2H2-type 4; atypical", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 4; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q2QX40", "organism_name": "Rice", "protein_name": "Zinc finger protein STAR3", "length": 465, "firstPublicDate": "2011-03-08", "FUNCTION": "Transcriptional activator that regulates the expression of genes involved in aluminum (Al) tolerance, Binds to the promoter of STAR1 and regulates transcript expression of STAR1 STAR2 and ART1 required for Al tolerance", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 1, "C2H2-type 2; atypical Zinc finger": 1, "C2H2-type 3; atypical Zinc finger": 1, "C2H2-type 4; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDRDQMTNTMRDQAANLTSMNPLFYPFMADDALLGMAPPPPQQLLPSVSIQHMDWSPDTMLDNLTFIEEKIRQVKDVIRSMAGRRASSSSAATPEQQLVNADLTCLIVQLISTAGSLLPSLKNSSFLSRTTPPPAAAAGAAQAVSLAAGESSSSARNNETNREDEEEQMGSPDYDELFKVWTNGGAMDECVGAAGDEQDARENPAAAAEEEKYEVLQLEEDEILAPHTHFCGICGKGFKRDANLRMHMRGHGDEYKSAAALAKPPPPPEGEEQPPQPERRYSCPHAGCKRNRMHASFQPLKTILCVKNHYKRSHCEKRHVCGRCGAKRFSVMADLKTHEKHCGRDRWLCSCGTSFSRKDKLFAHVALFQGHAPALPPPPPPPTSGRRRHKQEEPEFTWGGGGGNEFLDVKGIAGVGSGSGGGDEFFSAGSFGAMDFGFGQLDASLAMLLPSEQFAGDHQEENGDK", "length": 465, "molWeight": 50598, "crc64": "6D181ED0D4D3BD0D", "md5": "0E05E7F947E84D40EB527FAAE62CEF5A"}}
{"primaryAccession": "Q2VWH6", "text": "This is Fez family zinc finger protein 2 protein, from Bovine, contains 458 amino acids, has 6 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [276, 298], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [304, 326], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [332, 354], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [360, 382], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [388, 410], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [416, 439], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q2VWH6", "organism_name": "Bovine", "protein_name": "Fez family zinc finger protein 2", "length": 458, "firstPublicDate": "2007-07-10", "FUNCTION": "Transcription repressor, Binds to 5'GCAG-3' core sequence, Required for the specification of corticospinal motor neurons and other subcerebral projection neurons, May play a role in layer and neuronal subtype-specific patterning of subcortical projections and axonal fasciculation, Controls the development of dendritic arborization and spines of large layer V pyramidal neurons (By similarity), May be responsible for mastitis resistance and innate immunity", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 6}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASSASLETMVPPACPRAGASPATSKTLAFSIERIMAKTSEPRAPFEPRPGALEADSGQGKKLLNLCSPLPCMIPLQPLGYEMPSKTLLSYSELWKSSLRAGGSGGGGGGGGGGGGAPVCGASGLCKTNCGVCCKAELGLVPSALPAGRVIKPQVINQAVGLPASGSLYYFNYLDSATYPSSELLGGHLFPSGLLNTQAPAALAAHPKLFLLENAKLAGLTADKFAHPAPYAHKERLPAPLEQVLKENSALTAERGGVKGHSKLPGGSADGKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRKLHDSVGPAAPSTKDLTRTVQS", "length": 458, "molWeight": 48842, "crc64": "D947CDB723FA6F11", "md5": "7895C6B8F2AA4C9D8B27E41EE1156344"}}
{"primaryAccession": "Q3C1E9", "text": "This is Histone chaperone ASF1 protein, from Chicken, contains 204 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3C1E9", "organism_name": "Chicken", "protein_name": "Histone chaperone ASF1", "length": 204, "firstPublicDate": "2007-04-17", "FUNCTION": "Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly, Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly, May also cooperate with HIRA to promote replication-independent chromatin assembly", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ASF1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAESEEYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCTYRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFHINWEDNTEKLEDAESSNPNLQSLLSTDALPSASKGWSTSENSLNVMLESHMDCM", "length": 204, "molWeight": 22969, "crc64": "9819D531D3A9FC68", "md5": "E6727D155E947B7FE91115F4C02993EF"}}
{"primaryAccession": "Q3E705", "text": "This is rRNA-processing protein EFG1 protein, from Baker's yeast, contains 233 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3E705", "organism_name": "Baker's yeast", "protein_name": "rRNA-processing protein EFG1", "length": 233, "firstPublicDate": "2006-07-11", "FUNCTION": "Involved in rRNA processing, Required growth at elevated temperatures, resistance to hydroxyurea and for cell cycle progression", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the EFG1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAKLQRKRSKALGSSLEMSQIMDAGTNKIKRRIRDLERLLKKKKDILPSTVIIEKERNLQALRLELQNNELKNKIKANAKKYHMVRFFEKKKALRKYNRLLKKIKESGADDKDLQQKLRATKIELCYVINFPKTEKYIALYPNDTPSTDPKGVELTNLRREQFLKLVAERMDANTLNVSFEEILKGKKLDEDSIGLTLSPDKDHEDGSQVSPTQDRKELDQVVGEDEKDDFFE", "length": 233, "molWeight": 27121, "crc64": "5DB64BB999DA3510", "md5": "4883B7B2B3A1036D9F268A818A7C050E"}}
{"primaryAccession": "Q3E785", "text": "This is Succinate dehydrogenase assembly factor 1, mitochondrial protein, from Baker's yeast, contains 79 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3E785", "organism_name": "Baker's yeast", "protein_name": "Succinate dehydrogenase assembly factor 1, mitochondrial", "length": 79, "firstPublicDate": "2006-10-17", "FUNCTION": "Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol, Promotes maturation of the iron-sulfur protein subunit SDH2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants, Acts together with SDHAF3 (SDH7)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the complex I LYR family, SDHAF1 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPKRLSGLQKEVLHLYRASIRTAHTKPKENQVNFVNYIHEEFGKYRNLPRKDFTTIEHLLRVGNKKIATFSHPELTNIH", "length": 79, "molWeight": 9352, "crc64": "2A49008969061739", "md5": "8F2BEAE64105F5FEDCD9703B4B385AC1"}}
{"primaryAccession": "Q3KQU3", "text": "This is MAP7 domain-containing protein 1 protein, from Human, contains 841 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3KQU3", "organism_name": "Human", "protein_name": "MAP7 domain-containing protein 1", "length": 841, "firstPublicDate": "2007-10-02", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the MAP7 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MESGPRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQRWSWAGALHHSSPGHKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQENGFSTNGPSGDKSLSRTPETLLPFAEAEAFLKKAVVQSPQVTEVL", "length": 841, "molWeight": 92820, "crc64": "47F5931376A931EF", "md5": "C7A186EEC8E77028E81236B7B59E4511"}}
{"primaryAccession": "Q3KRE0", "text": "This is ATPase family AAA domain-containing protein 3 protein, from Rat, contains 591 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3KRE0", "organism_name": "Rat", "protein_name": "ATPase family AAA domain-containing protein 3", "length": 591, "firstPublicDate": "2007-12-04", "FUNCTION": "Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level, May play an important role in mitochondrial protein synthesis, May also participate in mitochondrial DNA replication, May bind to mitochondrial DNA D-loops and contribute to nucleoid stability, Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis, Involved in mitochondrial-mediated antiviral innate immunity", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the AAA ATPase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSWLFGIKGPKGEGTGPPLPLPPAQPGAESGGDRGAGDRPSPKDKWSNFDPTGLERAAKAARELEHSRHAKEALNLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERRKTLNEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELRHKNEMLRVEAEARARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATSVAGRYIEARLGKPSLVRETSRISVLEALRHPIQVSRRLVSRPQDALEGVILSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTAGMSGREIAQLAVAWQAMAYSSEDGVLTEAMMDARVQDAVQQHQQKMQWLKVERPDSEASKPPHPSLLSC", "length": 591, "molWeight": 66759, "crc64": "B436447F34E949DE", "md5": "0E247D45B91CD314F1661D6C23C3FD8C"}}
{"primaryAccession": "Q3TA38", "text": "This is Transmembrane protein 120B protein, from Mouse, contains 339 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3TA38", "organism_name": "Mouse", "protein_name": "Transmembrane protein 120B", "length": 339, "firstPublicDate": "2007-11-13", "FUNCTION": "Necessary for efficient adipogenesis (PubMed:26024229), Does not show ion channel activity (PubMed:32084332)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TMEM120 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSGQLERCEREWHELEGEFQELQETHRIYKQKLEELTSLQTLCSTSISKQKRHLKDLKHTLQRYKRHSSHEEAALIQQMTANIKERQNVFFDMEAYLPKKNGLYLNLVLGNVSVTLLSNQAKFAYKDEYEKFKLYLTIILLLGAVACRFVLHYRVTDEVFNFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSTFLSGVMLTWPNGLIYQKFRNQFLAFSIFQSCVQFLQYYYQRGCLYRLRALGERNHLDLTVEGFQSWMWRGLTFLLPFLFCGHFWQLYNAVTLFELSTHEECKEWQVFVLALTFLILFLGNFLTTLKVVHAKLHKNRNKTKQP", "length": 339, "molWeight": 40407, "crc64": "56FA0CF4045EDD76", "md5": "A72A9E99E4320BF45DB08ACB8CE70D92"}}
{"primaryAccession": "Q3ZBF7", "text": "This is Prostaglandin E synthase 3 protein, from Bovine, contains 160 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3ZBF7", "organism_name": "Bovine", "protein_name": "Prostaglandin E synthase 3", "length": 160, "firstPublicDate": "2007-05-29", "FUNCTION": "Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2), Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes, Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the p23/wos2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCIDPNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE", "length": 160, "molWeight": 18697, "crc64": "23538BB9D7AFD73F", "md5": "E5242919A9AEFE7A5A724041C1C6CC28"}}
{"primaryAccession": "Q3ZBI7", "text": "This is ATP synthase membrane subunit K, mitochondrial protein, from Bovine, contains 58 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3ZBI7", "organism_name": "Bovine", "protein_name": "ATP synthase membrane subunit K, mitochondrial", "length": 58, "firstPublicDate": "2006-04-04", "FUNCTION": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain, F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk, During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation, ATP5MK is a minor subunit of the mitochondrial membrane ATP synthase required for dimerization of the ATP synthase complex and as such regulates ATP synthesis in the mitochondria", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAGPEADAQFHFTGIKKYFNSYTLTGRMNCVLATYGSIALIVLYFKLRSKKTPAVKAT", "length": 58, "molWeight": 6435, "crc64": "1341E9CFE6C0B127", "md5": "DEE064CA22E2AB796E825E87521A79E0"}}
{"primaryAccession": "Q40161", "text": "This is Polygalacturonase-1 non-catalytic subunit beta protein, from Tomato, contains 630 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q40161", "organism_name": "Tomato", "protein_name": "Polygalacturonase-1 non-catalytic subunit beta", "length": 630, "firstPublicDate": "2005-11-22", "FUNCTION": "Non-catalytic subunit of the polygalacturonase isozyme 1 (PG1), Necessary and sufficient to convert the polygalacturonase from its monomeric form PG2 to its heterodimeric form PG1, Seems to limit the depolymerization and solubilization of cell wall polyuronides mediated by PG2 during ripening, probably by recruiting PG2 to form PG1", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MHTKIHLPPCILLLLLFSLPSFNVVVGGDGESGNPFTPKGYLIRYWKKQISNDLPKPWFLLNKASPLNAAQYATYTKLVADQNALTTQLHTFCSSANLMCAPDLSPSLEKHSGDIHFATYSDKNFTNYGTNEPGIGVNTFKNYSEGENIPVNSFRRYGRGSPRDNKFDNYASDGNVIDQSFNSYSTSTAGGSGKFTNYAANANDPNLHFTSYSDQGTGGVQKFTIYSQEANAGDQYFKSYGKNGNGANGEFVSYGNDTNVIGSTFTNYGQTANGGDQKFTSYGFNGNVPENHFTNYGAGGNGPSETFNSYRDQSNVGDDTFTTYVKDANGGEANFTNYGQSFNEGTDVFTTYGKGGNDPHINFKTYGVNNTFKDYVKDTATFSNYHNKTSQVLASLMEVNGGKKVNNRWVEPGKFFREKMLKSGTIMPMPDIKDKMPKRSFLPRVIASKLPFSTSKIAELKKIFHAGDESQVEKMIGDALSECERAPSAGETKRCVNSAEDMIDFATSVLGRNVVVRTTEDTKGSNGNIMIGSVKGINGGKVTKSVSCHQTLYPYLLYYCHSVPKVRVYEADILDPNSKVKINHGVAICHVDTSSWGPSHGAFVALGSGPGKIEVCHWIFENDMTWAIAD", "length": 630, "molWeight": 68960, "crc64": "31D585305D216AFE", "md5": "D104563A9F642C8B7080508EBBA4A37D"}}
{"primaryAccession": "Q40424", "text": "This is Lycopene beta cyclase, chloroplastic/chromoplastic protein, from Daffodil, contains 503 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q40424", "organism_name": "Daffodil", "protein_name": "Lycopene beta cyclase, chloroplastic/chromoplastic", "length": 503, "firstPublicDate": "2000-12-01", "FUNCTION": "Catalyzes the double cyclization reaction which converts lycopene to beta-carotene and neurosporene to beta-zeacarotene", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the lycopene cyclase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDTLLRTHNRLELLYPLHELAKRHFLSPSPNPQNPNFKFFSRKPYQKKCRNGYIGVSSNQLLDLVPEIKKEHLEFDLPLYDPSKALTLDLAVVGGGPLARSCSTSLGGGLSVVSIDPNPKLIWPNNYGVWVDEFEDMDLLDCLDATWSGAIVYVDDRSTKNLSRPYARVNRKNLKSKMMKKCVSNGVRFHQATVVKAMHEEEKSYLICSDGVTIDARVVLDATGFSRCLVQYDKPYNPGYQVAYGILAEVEEHPFDVDKMVFMDWRDSHLNGKAELNERNAKIPTFLYAMPFSSNRIFLEETSLVARPGLKMEDIQERMVARLNHLGIRIKSIEEDERCVIPMGGPLPVIPQRVVGIGGTAGMVHPSTGYMVARTLAAAPIVANSIVQYLVSDSGLSGNDLSADVWKDLWPIERRRQREFFCFGMDILLKLDLEGTRRFFDAFFDLEPRYWHGFLSSRLFLPELVPFGLSLFSHASNTCKLEIMAKGTLPLVNMINNLVQDRD", "length": 503, "molWeight": 56911, "crc64": "3FD1E355EF184D98", "md5": "FE5C7DE116E4F58C1CC796EF067C2155"}}
{"primaryAccession": "Q41738", "text": "This is Thiamine thiazole synthase 1, chloroplastic protein, from Maize, contains 354 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q41738", "organism_name": "Maize", "protein_name": "Thiamine thiazole synthase 1, chloroplastic", "length": 354, "firstPublicDate": "1997-11-01", "FUNCTION": "Involved in biosynthesis of the thiamine precursor thiazole, Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate, The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate, The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme, May have additional roles in adaptation to various stress conditions and in DNA damage tolerance", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the THI4 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATAAASSLLKSSFAGSRLPAATRTTPASLVVATGPRGAGAGPICASMSMSSSNPPYDLTSFRFSPIKESIVSREMTRRYMTDMITYADTDVVIVGAGSAGLSCAYELSKDPAVSIAIVEQSVSPGGGAWLGGQLFSAMVVRKPAHLFLDELGVAYDEAEDYVVIKHAALFTSTVMSLLLARPNVKLFNAVAVEDLIVRGGRVGGVVTNWALVSMNHDTQSCMDPNVMEAKVVVSSCGHDGPFGATGVKRLQDIGMISAVPGMKALDMNTAEDEIVRLTREVVPGMIVTGMEVAEIDGAPRMGPTFGAMMISGQKAAHLALKALGRPNAVDGTMSPPLREELMIAYKDDEVVDA", "length": 354, "molWeight": 37105, "crc64": "1D27B449CB9294DE", "md5": "0C14E14589927BA6A15640273173560A"}}
{"primaryAccession": "Q42599", "text": "This is NADH dehydrogenase [ubiquinone] iron-sulfur protein 8-A, mitochondrial protein, from Mouse-ear cress, contains 222 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q42599", "organism_name": "Mouse-ear cress", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8-A, mitochondrial", "length": 222, "firstPublicDate": "1998-12-15", "FUNCTION": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis, Complex I functions in the transfer of electrons from NADH to the respiratory chain, The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity), May donate electrons to ubiquinone", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the complex I 23 kDa subunit family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASILARRSLNTLRARHLVLSGQALQGSHLSRLQSRGISYGSNKDDEEAEQLSKEISKDWNTVFERSINTLFLTEMVRGLSLTLKYFFDPKVTINYPFEKGPLSPRFRGEHALRRYPTGEERCIACKLCEAVCPAQAITIEAEEREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETHEELLYDKEKLLENGDRWETEIAENLRSESLYR", "length": 222, "molWeight": 25503, "crc64": "7C1F2264B0D0631B", "md5": "6E427259458E1CFB238091EBDDABAAE6"}}
{"primaryAccession": "Q4WZ11", "text": "This is Elastase inhibitor AFUEI protein, from Neosartorya fumigata, contains 87 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q4WZ11", "organism_name": "Neosartorya fumigata", "protein_name": "Elastase inhibitor AFUEI", "length": 87, "firstPublicDate": "2008-10-14", "FUNCTION": "Elastase inhibitor, Non-competitive inhibitor of A,fumigatus elastase with a Ki of 1,6 nM, Inhibits the fibrinogenase and collagenase activities of A,fumigatus elastase, Inhibitor of A,flavus elastase and human leukocyte elastase, and weakly inhibits porcine pancreatic elastase, Does not inhibit elastase from P,aeruginosa or C,atrox venom", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFSLACLLALAGLQAALADPATCEKEAQFVKQELIGQPYTDAVANALQSNPIRVLHPGDMITMEYIASRLNIQVNENNEIISAHCA", "length": 87, "molWeight": 9413, "crc64": "64E569B7278F9C94", "md5": "034032E667C269B58F133322B33CAD76"}}
{"primaryAccession": "Q500W4", "text": "This is LIM domain-containing protein PLIM2c protein, from Mouse-ear cress, contains 213 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q500W4", "organism_name": "Mouse-ear cress", "protein_name": "LIM domain-containing protein PLIM2c", "length": 213, "firstPublicDate": "2014-10-29", "FUNCTION": "Binds to actin filaments and promotes cross-linking into thick bundles, Has an actin-stabilizing activity, Associates predominantly with long and dynamic actin bundles in the shank of growing pollen tubes, The actin regulatory activities are inhibited by pH > 6,8 and/or high [Ca(2+)]", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAFTGTTDKCKACDKTVYVMDLMTLEGMPYHKSCFRCSHCNGTLVICNYSSMDGVLYCKTHFEQLFKESGNFSKNFQTAGKTEKSNDATKAPNRLSSFFSGTQDKCAACKKTVYPLEKMTMEGESYHKTCFRCAHSGCPLTHSSYAALDGVLYCKVHFSQLFLEKGNYNHVLQAAANHRRSTAEEDKTEPKEDEANPTEEETSDAAAEEHES", "length": 213, "molWeight": 23765, "crc64": "D0A9758DA0388BD6", "md5": "76235538A63ABC9105C1CD908D6950A6"}}
{"primaryAccession": "Q54J33", "text": "This is P2X receptor D protein, from Social amoeba, contains 407 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q54J33", "organism_name": "Social amoeba", "protein_name": "P2X receptor D", "length": 407, "firstPublicDate": "2009-12-15", "FUNCTION": "P2X receptors are ligand-gated ion channels that play a role in intracellular calcium signaling, ATP does not evoke inward currents in p2xD, Not essential for osmoregulation", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the P2X receptor family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDWDNIFSYNTAKIVTIKDRRLGGLHIIFMVLIIVYIVIYSTIYKKGYLLTETPVGSIRASLLAPNEFKDDSNFKYCDDNLIEYNFTKLECDYYDEAFVSFPVGDDVSFAVTTRVKTLDQVLNCSSKNPKCKYTTVSTRNVYVSDIEDFTILIDHTMFAPSSLIQYNSKQLKGYILDNDNNEIQINETINTVGIPGKPDILTIGKLLQLANIDLDGASSVNSTNSVRYDGVVALVFITYSNTFSYNTNNFKYVYSIQKVEDTEYGVPEAVILDNVSSRMYYNRHGIRLIFIQNGEIGSFNFQALLLTFVSGLGLLAISTVLVDQLAIRFLPERKTYSSHKFQITHGFSESRNKLRISQNEKDPLLLVETTKNNENNNNNDDYNDDDNEIFDDNNNGYQNIQNNNIIL", "length": 407, "molWeight": 46362, "crc64": "650A51857F6E0D2E", "md5": "E20E030D51976CBE6B8690D63F5EE121"}}
{"primaryAccession": "Q553Y0", "text": "This is P2X receptor C protein, from Social amoeba, contains 368 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q553Y0", "organism_name": "Social amoeba", "protein_name": "P2X receptor C", "length": 368, "firstPublicDate": "2009-12-15", "FUNCTION": "P2X receptors are ligand-gated ion channels that play a role in intracellular calcium signaling, ATP does not evoke inward currents in p2xC, Not essential for osmoregulation", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the P2X receptor family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLDWDSILAYNTIKVVRIRDRRLGILHLIFMIAIISYVVIYSAIIKKGYLSIEEPVGSIRTSLWSPNQFNGNESYCKNNAKPYPYEKLDCVYYDDALALYPIGDDVGFTASTRIEISDQKANCSLMNPSCKFKTFNYSNVYLADIESFTVLIDHTMYAPSSQIQFNGGDLSGYVLDQNGNEIQLNESVNVIGVEGKPDVLEISKLLEFAGVNLDDPSLTNSSNPIRYDGCVLFVFIEYSNTFSYDLNKIKYVYSIKLVDDTIYNIPEVVILDDVNSRLYYKRHAIRLIFIQTGVIGSFNFQSLLLTLVSGLGLLTVSTLIVDQLAIRFLPQRKSYSSLKFQTTESFKMKKKIVNDDGEDKLYHNIEAL", "length": 368, "molWeight": 41756, "crc64": "2B3ECD56CB108700", "md5": "9087AEF308137377812736D8AB11D4EA"}}
{"primaryAccession": "Q59NP1", "text": "This is Copper transport protein CTR1 protein, from Yeast, contains 251 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q59NP1", "organism_name": "Yeast", "protein_name": "Copper transport protein CTR1", "length": 251, "firstPublicDate": "2013-06-26", "FUNCTION": "Required for high affinity copper (probably reduced Cu I) transport into the cell", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEFLKRHEGHMHMSDSATSMVTSATSAVMDMASATMSMTMSSSTSSSSGMAMEGMDHGSSHMAMNMWLTASFKDYPVVFKDLRASTKAQAFGIFVLLFFVAFLARMLEFVRNYLEEIVWKNNNYAEVEQGISQHSANLQSPPVKSCCDDNAKEVVSDESIDKQNSPQHEETTKARGTGKSLSLASTISRDIIRLALCIIPDLFAYSLMLAAMTYTLTYFFAVVIGSGVGRFVAERLMEHYRIKRGPPRNCC", "length": 251, "molWeight": 27859, "crc64": "07DEEC1675196F64", "md5": "A261DAC417CD52C585707D43203B3411"}}
{"primaryAccession": "Q59YT1", "text": "This is MFS antiporter QDR2 protein, from Yeast, contains 504 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q59YT1", "organism_name": "Yeast", "protein_name": "MFS antiporter QDR2", "length": 504, "firstPublicDate": "2015-01-07", "FUNCTION": "MFS antiporter that does not display functional linkage as drug transporter and performs functions that significantly affect biofilm development and virulence, No substrate for transport has been identified yet, but plays an important role in the growth in the host", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator superfamily, CAR1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLSTTQSVTEPTEVTSKKVEDIEKENDEETPYSIFTSYDRLVLIVILSLIGFWSTISSPIYFPALPTLTSYFHTSSSIMNISVVAYLIFQGIAPTISSNLADTFGRRPVILASIIVFCASCVAISQTNVYWLLAVLRCIQAAGIAAVISISSGVAGDVCTRANRGSMVGAVAGLQLVGNGIGGLVGAALISSFNSWRSIFIFLTIGGGVTFILAIFILPETSRKLVGNGSVVPKNILNKSPYIYLPHFKKRMNNDITTIVPATRFDLLGPLKIFFQKNVFCTLLPVGIHFAAWTMVLTSLSTELESRYHYSVMHVGLIYLPQGIACIAGSLVVGKSLDWYYRYRKTIYDQEVECLPLDERPQFNIVATRLTLSVVPALLMIIGLVIFGWCIQYKRHIISIIISTILVSFSASVFIAICTTMLVDLYPNNGSGSTSCLNLMRCWLAALGAGVLDSMINAMNVGGTYTVVAGFCILFDLALIYVLHNAKKKFSNSGPTTTKSPPKQ", "length": 504, "molWeight": 54897, "crc64": "626CC2DD444FF496", "md5": "7D314A96E4ACBA23E21F494D0A538FB3"}}
{"primaryAccession": "Q5A6P6", "text": "This is MFS antiporter QDR1 protein, from Yeast, contains 509 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5A6P6", "organism_name": "Yeast", "protein_name": "MFS antiporter QDR1", "length": 509, "firstPublicDate": "2015-01-07", "FUNCTION": "MFS antiporter that does not display functional linkage as drug transporter and performs functions that significantly affect biofilm development and virulence, No substrate for transport has been identified yet, but plays an important role in the growth in the host", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator superfamily, CAR1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPGNREEFDIEKVLKSKKLEAIETSTEKKAPYTVFESTDKLLLIIVLSLVGFWSAISSPIYFPALPTLTKYFNTTPSVMNISVVAYLIFQGIAPTISSNLADTFGRRPVILGSIIVFCAVCIAISQTNVYWLLALLRCFQAAGIAPVFAISSGVAGDICTPANRGGMVGAVSGLQLAGNGIGGLVGAALISGFHTWRAIFIFLAIGGGVTFIFAFLVLAETSRRIVGNGSIRPKNVLNKAVLIYLPHFKNKITNDYSTLQPKGPFDILGPFKIFFQKEVFCTLLPSGMHFAAWTVSLTSLSTELESAKYNYSVMKVGLVYLPQGIACFIGSLIAGRCLNWYYRYRKNLYDKQMNDVPLNDRPPFNLVASRLTLTIVPLAMMVIGLSAFGWCLEYKKPIISIIISTILISFSASVMMSICTTMLVDLYPKQSGASASCVNLMRCWLAALFTGVLDKIISALGLGGTYTLLTGICLLTDLGLVYVLYTANQRFVNYVSPNQTAVNSDAEDY", "length": 509, "molWeight": 55432, "crc64": "612FFB8DA3E57073", "md5": "0B91DDCC3B3793EE524B3B4CDCE01A88"}}
{"primaryAccession": "Q5A961", "text": "This is Actin-regulating kinase PRK1 protein, from Yeast, contains 690 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5A961", "organism_name": "Yeast", "protein_name": "Actin-regulating kinase PRK1", "length": 690, "firstPublicDate": "2013-11-13", "FUNCTION": "Protein kinase involved in regulation of actin cytoskeleton organization and endocytosis, Phosphorylates the endocytic protein SLA1, The CDC28-CLN3 complex phosphorylation of SLA1 enhances its further phosphorylation by PRK1, weakening SLA1 association with PAN1, an activator of the actin-nucleating ARP2/3 complex, Plays a role in cell wall regulation and required for oxidative stress survival", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPQPPPNAYKAGTRLTVGSHKVSIIKYISEGGFAHVYTCTIDPPFQGSTVACLKRVVVPSKWQLSLLRQEVDAMRRLRGNKHIVSYIDSHASRLGDSNTSGTNHSQQQQYEVFLLMEYCENNGLIDFMNTRLVNKLTEKEIIDIMYQVTIGVAMCHHLRPPLIHRDIKIENVLIDGKGVFKLCDFGSSVNYLPPPRNPQELQLMKDDLMQHTTPQYRAPEMIDLSKGFPIDDKSDIWALGIFLYKLCYYTTPFERPNQSSLQELEHTILNCSETLRFSDQPGSIFSPRLKNAIKVCLRADPRRRPNAVQLLGEIAAMKGEKTIPNVVPYSVIEQQRTKQASALEEDTKKGQASFVETKKITSKPKTDPFANIDKSKFLNKSGYKLSSVTAESRTVPARPLSAFFDDGNTPRIYSQGNRSTPSVQDYVKEELAKGESYEFNEPDGTLEFLKSREEEKLNQRNDTGGSFKAAFKNGLRKISTGGNISANNTGSSVKSNRRASLKRIITGGSNHNRKHSEENTKNVEDSNPVSSAPKKLSIQHRMQQLLNQNDHQRVQKSAQGYGKYTDIKASEDIDEINKPTLSKHSQKKLSPPAVPVNLSSQRNKSQQSSSTTKKYPIKDSKPLSKVRNNPPKDSVKTKPPPPKPKKPVYLKSPTKLEIADQRRLSDASEISMPDLDDLEKQFSKRFPSYV", "length": 690, "molWeight": 77639, "crc64": "DB391E40775ECB13", "md5": "92CE279BB58E5752E2BBB1779E5EF237"}}
{"primaryAccession": "Q5AB48", "text": "This is Secreted protein RBT4 protein, from Yeast, contains 358 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5AB48", "organism_name": "Yeast", "protein_name": "Secreted protein RBT4", "length": 358, "firstPublicDate": "2014-01-22", "FUNCTION": "Secreted protein that acts as a virulence factor during infections such as in posttraumatic corneal infections, Acts as an important antigen in patients with systemic candidiasis and plays a role in the protection against phagocyte attack", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the CRISP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFSQVATTAAIFAGLTTAEIAYVTQTRGVTVGETATVATTVTVGATVTGGDQGQDQVQQSAAPEAGDIQQSAVPEADDIQQSAVPEAEPTADADGGNGIAITEVFTTTIMGQEIVYSGVYYSYGEEHTYGDVQVQTLTIGGGGFPSDDQYPTTEVSAEASPSAVTTSSAVATPDAKVPDSTKDASQPAATTASGSSSGSNDFSGVKDTQFAQQILDAHNKKRARHGVPDLTWDATVYEYAQKFADQYSCSGNLQHSGGKYGENLAVGYADGAAALQAWYEEAGKDGLSYSYGSSSVYNHFTQVVWKSTTKLGCAYKDCRAQNWGLYVVCSYDPAGNVMGTDPKTGKSYMAENVLRPQ", "length": 358, "molWeight": 37449, "crc64": "12BF8DD776918B8E", "md5": "C6437D6181DCB7B3EC169DE208458964"}}
{"primaryAccession": "Q5E930", "text": "This is S-type anion channel SLAH1 protein, from Mouse-ear cress, contains 385 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5E930", "organism_name": "Mouse-ear cress", "protein_name": "S-type anion channel SLAH1", "length": 385, "firstPublicDate": "2011-02-08", "FUNCTION": "Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the SLAC1 S-type anion channel family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEIPRQEIHIEIDNSIPSSKEFKTGLADAKPVVLMSALRSLHAGYFRISLSLCSQALLWKIMIAPESPSMSHMHSKLPSMAFHLLWYLALVTQVSLCFLYALKCIFFFDKVKEEFLHYIGVNYLYAPSISWLLMLQSAPMMEPNSVLYQTLFWIFAVPVLTLDIKLYGQWFTTEKRFLSMLANPASQVSVIANLVAARGAAEMGWNECALCMFSLGMVHYLVIFVTLYQRLPGGNNFPAKLRPIFFLFVAAPAMASLAWNSICGTFDAVAKMLFFLSLFIFMSLVCRPNLFKKSMKRFNVAWWAYSFPLTFLALDSVQYAQEVKDPVGSGLMLIFSSISVLIFLGMMVLTAANSNRLLRHDPVLGSATDPKDKQKTLSLNATNQN", "length": 385, "molWeight": 43407, "crc64": "C29F4BCC0AD81991", "md5": "61616B1C6876C8C1EFF79CEC2858C624"}}
{"primaryAccession": "Q5EA95", "text": "This is Intraflagellar transport protein 57 homolog protein, from Bovine, contains 429 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5EA95", "organism_name": "Bovine", "protein_name": "Intraflagellar transport protein 57 homolog", "length": 429, "firstPublicDate": "2008-04-08", "FUNCTION": "Required for the formation of cilia, Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway, Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis, Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the IFT57 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAAAAAVVTPSGLEDEVSRSRGEGAGEMVVERGPGAAYHMFVVMEDLVEKLKLLRYEENLLRKNNLKPPSRHYFALPTNPGEQFYMFCTLAAWLINKAGRPFEQPQEYDDPNAIISNILSELRSFGRTADFPPSKLKSGYGEHVCYVLDCLAEEALKYIGFTWKRPAYPVEELEEETVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYRLDMNESAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHKSGIESALKETKGFLDRLHNEISRTLEKIGSREKYINNQLEHLVQEYRAAQAQLSEARERYQQGNGGVTERTRILSEVTEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVQMDIRIGVVEHTLLQSKLKEKSNMTRDMHATIIPESAIGSY", "length": 429, "molWeight": 48960, "crc64": "C83DCD427CA311E2", "md5": "DFB8042FA818149D01E2B64D2DFCE136"}}
{"primaryAccession": "Q5FWP4", "text": "This is E3 ubiquitin-protein ligase CHFR protein, from African clawed frog, contains 625 amino acids, has 1 RING-type Zinc finger, has 1 PBZ-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [266, 305], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}, {"location": [594, 616], "description": "PBZ-type", "keyword_description": "Zinc finger", "textural_description": "PBZ-type Zinc finger"}], "meta_data": {"primaryAccession": "Q5FWP4", "organism_name": "African clawed frog", "protein_name": "E3 ubiquitin-protein ligase CHFR", "length": 625, "firstPublicDate": "2009-09-22", "FUNCTION": "E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons, Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus, Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome, May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating ubc13-mms2 (ube2n-ube2v2) heterodimer, Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CHFR family", "domain_description": {"RING-type Zinc finger": 1, "PBZ-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEGLDEKKPWGKLSRLLGAETDSSSELFLYKKEWTIGRKKACDLSFPGNKLVSGEHCKITVNEESGEVSLEDTSTNGTVINKLKVIRKQTYPLKNGDVIYVVYRKNEPEQNVAYLYKSLNQGQDSLHDPADTSGSEEAETQTLSSQDDQLSYEEPQPSTSTSSLFSTPTTSAIPGVQLESAEKSGESLGGHSSTSDASPAIRASIPKSNLSTQEQGSLGPPKKRIRTEDHWTTNKNFVPASCPIGASDESKTPSMKPDKMEETLTCIICQELLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLIQHPEKCRSEEDRCSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYTVCRQCPGFVRHSMQPPPYPPPSDTETSRTQGDAPSTSTNFPTATQEYVCPSHGSHVICTCCFQPMPDRRAEREHNSHVAPQQCTICLEPFCHMYWGCNRMGCFGCLAPFCELNLGDKCLDGVLNNNNYESDILKNYLASRGLTWKDMLNESLAAVQRGVFMLPDYRINGTTVLCYFCGLRNFRILTYQYRQNIPASELPVTVTSRPNCYWGRNCRTQVKAHHAMKFNHICEQTRFKN", "length": 625, "molWeight": 70019, "crc64": "72C0A497D48F6BDC", "md5": "7E36BAD722F5734968179D19BED90851"}}
{"primaryAccession": "Q5JNS0", "text": "This is Transcription factor TIP2 protein, from Rice, contains 379 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5JNS0", "organism_name": "Rice", "protein_name": "Transcription factor TIP2", "length": 379, "firstPublicDate": "2014-07-09", "FUNCTION": "Transcription factor that binds to the E-box-containing promoter regions of the transcription factors TDR and EAT1, activating their expression, May have a role in specifying the cell pattern of the inner anther walls and functioning in meiosis progression, Required for male reproduction (PubMed:24755456), Acts downstream of UDT1 and GAMYB, but upstream of TDR1 and EAT1 in pollen development (PubMed:24894043)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bHLH protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MYHPQCELLMPLESLEMDVGQSHLAAAVAAAMPGELNFHLLHSLDAAAAAASSTAASASSQPTVDYFFGGADQQPPPPAAMQYDQLAAPHHHQTVAMLRDYYGGHYPPAAAAAAATEAYFRGGPRTAGSSSLVFGPADDESAFMVGPFESSPTPRSGGGRKRSRATAGFHGGGPANGVEKKEKQRRLRLTEKYNALMLLIPNRTKEDRATVISDAIEYIQELGRTVEELTLLVEKKRRRREMQGDVVDAATSSVVAGMDQAAESSEGEVMAAAAMGAVAPPPRQAPIRSTYIQRRSKETFVDVRIVEDDVNIKLTKRRRDGCLAAASRALDDLRLDLVHLSGGKIGDCHIYMFNTKIHSGSPVFASAVASRLIEVVDEY", "length": 379, "molWeight": 40706, "crc64": "88840ACC6D4353B5", "md5": "C8BE1BFAEAF2DAC45E968817E4144B45"}}
{"primaryAccession": "Q5NCS9", "text": "This is Mitochondrial dynamics protein MID49 protein, from Mouse, contains 454 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5NCS9", "organism_name": "Mouse", "protein_name": "Mitochondrial dynamics protein MID49", "length": 454, "firstPublicDate": "2007-11-13", "FUNCTION": "Mitochondrial outer membrane protein which regulates mitochondrial organization, It is required for mitochondrial fission and promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins, Regulates DNM1L GTPase activity", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MID49/MID51 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAEFSQKQRKQSGSEGLGSVVDFLLANARLVLGVGGAAVLGIATLAVKRLIDRATSPPDEDDTKGDSWKELSLLRATSPQKPQPPPAAFSQPLATGSPSPSVPVEPTPIHSPTTPKFSTIAPLCLTFQERLLAFERKHVITPEAHVTLAKQLAGDIALELQAYLRSKFPELPFGALVPGGPLYDGLQAGTAEHVRLLAPLELEPGLWSLVPGVDTVAREPRCWAVRRTQLEFHPRGCSPWDRFLVGGYLSSRVLLELLRKALSASVNWPAIGSLLGCLIWPDVASEELLLKVQHECLEFTLAVLMVVPGASTDDRLLLAWPLEGLASNLWLQDLYPVETARLRALDDQDAGTRRRLLLLLCGICRGHPALVRLGWSHLTQVVLHLGEEEVAWTEEALGERFLQALEFLVGSLEQASLPCHFNPSVNLLGNFREEEIDDIGYVLYSGLQVPESLF", "length": 454, "molWeight": 49624, "crc64": "11CF1EF2C2CAB666", "md5": "E09792F4F054912691DD71DEE77D9F48"}}
{"primaryAccession": "Q5QHG5", "text": "This is Leucine aminopeptidase 1 protein, from Athlete's foot fungus, contains 373 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5QHG5", "organism_name": "Athlete's foot fungus", "protein_name": "Leucine aminopeptidase 1", "length": 373, "firstPublicDate": "2009-09-22", "FUNCTION": "Extracellular aminopeptidase which contributes to pathogenicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M28 family, M28E subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLLSVLALSATATSVLGASIPVDARAEKFLIELAPGETRWVTEEEKWELKRKGQDFFDITDEEVGFTAAVAQPAIAYPTSIRHANAVNAMIATLSKENMQRDLTKLSSFQTAYYKVDFGKQSATWLQEQVQAAINTAGANRYGAKVASFRHNFAQHSIIATIPGRSPEVVVVGAHQDSINQRSPMTGRAPGADDNGSGSVTILEALRGVLRDQTILQGKAANTIEFHWYAGEEAGLLGSQAIFANYKQTGKKVKGMLNQDMTGYIKGMVDKGLKVSFGIITDNVNANLTKFVRMVITKYCSIPTIDTRCGYACSDHASANRNGYPSAMVAESPIDLLDPHLHTDSDNISYLDFDHMIEHAKLIVGFVTELAK", "length": 373, "molWeight": 40635, "crc64": "7754DE880535DF81", "md5": "DC683A01BEDDC275B215E22B6EA62B4B"}}
{"primaryAccession": "Q5QHG6", "text": "This is Leucine aminopeptidase 2 protein, from Athlete's foot fungus, contains 495 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5QHG6", "organism_name": "Athlete's foot fungus", "protein_name": "Leucine aminopeptidase 2", "length": 495, "firstPublicDate": "2009-09-22", "FUNCTION": "Extracellular aminopeptidase that releases a wide variety of amino acids from natural peptides and contributes to pathogenicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M28 family, M28A subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKSQLLSLAVAVTTISQGVVGQEPFGWPFKPMVTQDDLQNKIKLKDIMAGVEKLQSFSDAHPEKNRVFGGNGHKDTVEWIYNEIKATGYYDVKKQEQVHLWSHAEAALNANGKDLKASAMSYSPPASKIMAELVVAKNNGCNATDYPANTQGKIVLVERGVCSFGEKSAQAGDAKAAGAIVYNNVPGSLAGTLGGLDKRHVPTAGLSQEDGKNLATLVASGKIDVTMNVISLFENRTTWNVIAETKGGDHNNVIMLGAHSDSVDAGPGINDNGSGSIGIMTVAKALTNFKLNNAVRFAWWTAEEFGLLGSTFYVNSLDDRELHKVKLYLNFDMIGSPNFANQIYDGDGSAYNMTGPAGSAEIEYLFEKFFDDQGIPHQPTAFTGRSDYSAFIKRNVPAGGLFTGAEVVKTPEQVKLFGGEAGVAYDKNYHRKGDTVANINKGAIFLNTRAIAYAIAEYARSLKGFPTRPKTGKRDVNPQYSKMPGGGCGHHTVFM", "length": 495, "molWeight": 53309, "crc64": "291D29C958A9813F", "md5": "39726A2F129DC725178E4B5043EBFE5B"}}
{"primaryAccession": "Q5RLM2", "text": "This is Solute carrier family 22 member 7 protein, from Rat, contains 535 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5RLM2", "organism_name": "Rat", "protein_name": "Solute carrier family 22 member 7", "length": 535, "firstPublicDate": "2008-02-05", "FUNCTION": "Mediates sodium-independent multispecific organic anion transport, Transport of ketoprofen, indomethacin, salicylate, acetylsalicylate, prostaglandin E2, 3'-azido-3'-deoxythymidine (AZT), 2',3'-dideoxycytidine (ddC), dicarboxylates and p-aminohippurate (PAH)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGFEDLLDKVGGFGPFQLRNLVLMALPRMLLPMHFLLPVFMAAVPAHHCALPGAPANLSHQDLWLEAHLPRETDGSFSSCLRFAYPQTVPNVTLGTEVSNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRRLLLVAYVSSLVLGLMSAASINYIMFVVTRTLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTVFWSGGVLLLALVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLLSCAKLNGRPVGEGSLSQEALNNVVTMERALQRPSYLDLFRTSQLRHISLCCMMVWFGVNFSYYGLTLDVSGLGLNVYQTQLLFGAVELPSKIMVYFLVRRLGRRLTEAGMLLGAALTFGTSLLVSLETKSWITALVVVGKAFSEAAFTTAYLFTSELYPTVLRQTGLGLTALMGRLGASLAPLAALLDGVWLLLPKVAYGGIALVAACTALLLPETKKAQLPETIQDVERKSTQEEDV", "length": 535, "molWeight": 58654, "crc64": "E7C38969DCAE2B73", "md5": "B7436CF7DE1C9A75DC7AF88E60B58B8F"}}
{"primaryAccession": "Q5VYS4", "text": "This is Mesenteric estrogen-dependent adipogenesis protein protein, from Human, contains 303 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5VYS4", "organism_name": "Human", "protein_name": "Mesenteric estrogen-dependent adipogenesis protein", "length": 303, "firstPublicDate": "2007-02-06", "FUNCTION": "Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAGAACEPVARPSLTSISSGELRSLWTCDCELALLPLAQLLRLQPGAFQLSGDQLVVARPGEPAAARGGFNVFGDGLVRLDGQLYRLSSYIKRYVELTNYCDYKDYRETILSKPMLFFINVQTKKDTSKERTYAFLVNTRHPKIRRQIEQGMDMVISSVIGESYRLQFDFQEAVKNFFPPGNEVVNGENLSFAYEFKADALFDFFYWFGLSNSVVKVNGKVLNLSSTSPEKKETIKLFLEKMSEPLIRRSSFSDRKFSVTSRGSIDDVFNCNLSPRSSLTEPLLAELPFPSVLESEETPNQFI", "length": 303, "molWeight": 34190, "crc64": "AAE14F897EA2C484", "md5": "95A99F336FB5A81F6314D617BE0D75FB"}}
{"primaryAccession": "Q5XEN5", "text": "This is Methyl-CpG-binding domain-containing protein 1 protein, from Mouse-ear cress, contains 204 amino acids, has 1 CW-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [49, 104], "description": "CW-type", "keyword_description": "Zinc finger", "textural_description": "CW-type Zinc finger"}], "meta_data": {"primaryAccession": "Q5XEN5", "organism_name": "Mouse-ear cress", "protein_name": "Methyl-CpG-binding domain-containing protein 1", "length": 204, "firstPublicDate": "2011-03-08", "FUNCTION": "Probable transcriptional regulator", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"CW-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLPFPAMNLKKSRSENSSVASSGSKIEEQTEKSAEPTTIKVQKKAGTPGRSIDVFAVQCEKCMKWRKIDTQDEYEDIRSRVQEDPFFCKTKEGVSCEDVGDLNYDSSRTWVIDKPGLPRTPRGFKRSLILRKDYSKMDAYYITPTGKKLKSRNEIAAFIDANQDYKYALLGDFNFTVPKVMEETVPSGILSDRTPKPSRKVTID", "length": 204, "molWeight": 23152, "crc64": "E03DADF5CD15E284", "md5": "29D695C1D7E6CE926BAA77511A3118AD"}}
{"primaryAccession": "Q5XF06", "text": "This is Mitochondrial import inner membrane translocase subunit TIM44-2 protein, from Mouse-ear cress, contains 469 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5XF06", "organism_name": "Mouse-ear cress", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM44-2", "length": 469, "firstPublicDate": "2013-02-06", "FUNCTION": "Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner, Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the Tim44 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASRKLVRDLLITKQPLLQQLVHQRRVGARLGLLQGNGFASHRRFSVFSEFSKKIRGEADSNPEFQKTVKEFKERAEELQGVKEDLKVRTKQTTEKLYKQGQGVWTEAESVAKKVSSSVKDKFSAATEEVKESFKLGKEESAESASSSGTGTTEGEKQQQQSGSTEEQDTFFGKFKSSISSPKLSEAFHKPLDFAKKGLDIVKDELRGNPSKRKHLEYTPPPPFTGERSTRTEMVIMPTKQSKWQKKWESLREKMQGYPVFKRLSGMSEPVVNKSQEIAEDVREKWETSDNPIVHKIQDMNERIFEETGSASTYKEIRRRDPSFSLPDFVSEIQEAIRPVLNAYSKGDAKTLKKYCSKELIERCTAEHRAFTSQGYFFDHKLLHVSEVDIQETKMMGTTPVIIVRFQTQEIFCVRDQDGKIKEGGQDTIHTVYYDWAMQQVDAAELGEDAIYPIWRLREMLRAGVQALI", "length": 469, "molWeight": 53646, "crc64": "5E90C81E8A1FD1DA", "md5": "60D958344E57E8DBA8C75E1B6E837FC5"}}
{"primaryAccession": "Q5XF36", "text": "This is Vacuole membrane protein KMS1 protein, from Mouse-ear cress, contains 416 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5XF36", "organism_name": "Mouse-ear cress", "protein_name": "Vacuole membrane protein KMS1", "length": 416, "firstPublicDate": "2014-11-26", "FUNCTION": "Involved in the early secretory pathway, Required for the correct export of secretory products from the endoplasmic reticulum (ER) and involved in the maintenance of ER integrity", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the VMP1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGSAGVASSSSDVAISALREKHEKEVENLTLTTQPLNTLKLFVEATIQYIKRSISYLLAHGGWFILITTLLVVSGGLLVTVDGPHGKHVEEVLEYVRYGLWWIALGVASSIGLGSGLHTFVLYLGPHIALFTLKATLCGRVDLKSAPYDTIQLKRVPSWLDKSCSEFGPPLMISAAGSRVPLTSILPQVQLEAILWGIGTALGELPPYFISRAASISGSTVDGMEELDGSSTEDSGFMATHLNRVKRWLLTHSQHLNFFTVLVLASVPNPLFDLAGIMCGQFGIPFWEFFLATLIGKAIIKTHIQTIFIICVCNNQLLDWMENELIWILSHVPGLASMLPGLTAKLHAMKEKYIDAPSPVPSHIKVKKWDFSFASIWNGIVWLMLLNFFVKIVTATAQRHLKKKQEKEMATLTHSD", "length": 416, "molWeight": 45848, "crc64": "593ED01EBCD49E75", "md5": "FC9C290A8087097177E4D775F762559C"}}
{"primaryAccession": "Q5XIX0", "text": "This is DnaJ homolog subfamily C member 14 protein, from Rat, contains 703 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5XIX0", "organism_name": "Rat", "protein_name": "DnaJ homolog subfamily C member 14", "length": 703, "firstPublicDate": "2006-07-25", "FUNCTION": "Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAQKHPGERGLCGVHHSGGSSLITSGSSVDPEILSFSGLRDSKETAPNGTRCLKEHSDPKCTQPPNPAHWSDPSHGPPRGPGPPREGGYPDESETCSEESGVDQELSRENETGYQEDGSPSFLPIPSACNCQGSPGVPEGTCSEEGDGSSSSFCHHCTSPALGEDEELEEEYDDEEPLKFPSDFSRVSSGKKPPSRRQRHRFLTKEDVRDSGRRDPKAPGRHRLARKRSQTDKRRGLGLWGVEELCQLGQAGFWWLIELLVLVGEYVETCGYLIYACRKLKGSDLDLFRIWVGVWARRLGGWARVMFQFLSQSFFSVAGLFIRLLRVVGAFLLLALALFLGCLQLGWRFLVGLGDRLGWRGKAAWLFSWLDSPALHHFLTLLKDSRPWQQLVRVIQWGWLELPWVKQRTQRQGTAHVASGRYCQPEEEVARLLTMAGVPEDELNPFHVLGVEATASDIELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNPERRKEYEMKRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFGSRVPGTSGRQRATPESPPADLQDFLSRIFQVPPGPMSNGNFFAAPHPGPGTTSTSRPNSSVPKGEAKPKRRKKVRRPFQR", "length": 703, "molWeight": 79017, "crc64": "5D282F8A78DA2B08", "md5": "3D48EF6460270E18A7D4E3D34F00F423"}}
{"primaryAccession": "Q60547", "text": "This is Synaptonemal complex protein 3 protein, from Golden hamster, contains 234 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q60547", "organism_name": "Golden hamster", "protein_name": "Synaptonemal complex protein 3", "length": 234, "firstPublicDate": "1998-07-15", "FUNCTION": "Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:7876343), Required for centromere pairing during meiosis in male germ cells, Required for normal meiosis during spermatogenesis and male fertility, Plays a lesser role in female fertility, Required for efficient phosphorylation of HORMAD1 and HORMAD2", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the XLR/SYCP3 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVPGGRKHSGKSGKPPLVDQAKTAFDFEKEDKELSGSEEDVADEKTPVIDKHGKKRSGGLVEDVGGEVQNMLEKFGADINKALLAKRKRIEMYTKASFKASNQKIEQIWKTQQEEIQKLNSEYSQQFMSVLQQWELDMQKFEEQGEKLTNLFRQQQKIFQQSRIVQSQRLKAIKQLHEQFIKNLEDVEKNNDNLFTGTQSELKKEMAMLQKKVMMETQQQEMANVRKSLQSMLF", "length": 234, "molWeight": 27134, "crc64": "7965AEDD9B989BF6", "md5": "125ED8F87D8698D263F1C15C40783D35"}}
{"primaryAccession": "Q67ZM4", "text": "This is Actin-depolymerizing factor 7 protein, from Mouse-ear cress, contains 137 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q67ZM4", "organism_name": "Mouse-ear cress", "protein_name": "Actin-depolymerizing factor 7", "length": 137, "firstPublicDate": "2007-02-20", "FUNCTION": "Actin-depolymerizing protein, Severs actin filaments (F-actin) and binds to actin monomers, Binds monomeric actin (G-actin) with a marked preference for the ADP-loaded form and inhibits the rate of nucleotide exchange on G-actin, Required for pollen tube growth, Promotes turnover of longitudinal actin cables by severing actin filaments in pollen tubes", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the actin-binding proteins ADF family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MANAASGMAVEDECKLKFLELKSKRNYRFIIFRIDGQQVVVEKLGNPDETYDDFTASLPANECRYAVFDFDFITDENCQKSKIFFIAWSPDSSRVRMKMVYASSKDRFKRELDGIQVELQATDPSEMSFDIIKSRAL", "length": 137, "molWeight": 15820, "crc64": "A6484EF92403FDFD", "md5": "4EBC4F6D78D58D49BF4F69C29A66C73B"}}
{"primaryAccession": "Q68KK0", "text": "This is Phospholipase A1 protein, from Red imported fire ant, contains 346 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q68KK0", "organism_name": "Red imported fire ant", "protein_name": "Phospholipase A1", "length": 346, "firstPublicDate": "2010-11-30", "FUNCTION": "Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity), Induces hemolytic activity (By similarity), Acts as an allergen (PubMed:3192865)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRKFAAIFVVFFVQCTHLYSLAQARAEPDPGVVEYLKQSCVYGNSSYINVYLYNSRFQGKNLGNQQSCQDINASLPVVFITHGFTSSAQVSTFKDLANAFVQKGHTAFIVDWSEAACTDGLPGVQFAEYNAAASNTYDIGQLMAKYTVDLMNKCKIPLNNIQYVGHSLGSHVCGFAAKHVKKLINKTMPYILALDPADPSFGSNKCGERICKSDAKRIVVFKTSILGIGENIIGHLLIVFDGGKSQPACSWYDVPCSHSESIVYATGMVSGRCQHLAVPWTAQQRINPIQWKFWRVFTSNIPAYPTSDTTNCVVLNTNVFKNDNTFEGEYHAFPDCARNLFKCRQQ", "length": 346, "molWeight": 38417, "crc64": "B0A88EC6C3D876BF", "md5": "78C57FDB7C45FD052F16F8A301AEB0F6"}}
{"primaryAccession": "Q69IL4", "text": "This is Transcription factor RF2a protein, from Rice, contains 380 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q69IL4", "organism_name": "Rice", "protein_name": "Transcription factor RF2a", "length": 380, "firstPublicDate": "2005-07-05", "FUNCTION": "Transcription factor probably involved in vascular development and shoot tissue organization, Binds to the DNA sequence 5'-CCGAGTGTGCCCCTGG-3' present in the promoter region Box II of the phloem-specific rice tungro bacilliform virus (RTBV) promoter, May regulate tissue-specific expression of the RTBV promoter and virus replication", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNREKSPIPGDGGDGLPPQATRRAGPPAAAAAAEYDISRMPDFPTRNPGHRRAHSEILSLPEDLDLCAAGGGDGPSLSDENDEELFSMFLDVEKLNSTCGASSEAEAESSSAGAAAAVAAAAAAAAHGARPKHQHSLSMDESMSIKAEELVGASPGTEGMSSAEAKKAVSAAKLAELALVDPKRAKRIWANRQSAARSKERKMRYIAELERKVQTLQTEATTLSAQLALLQRDTSGLTTENSELKLRLQTMEQQVHLQDALNDTLKSEVQRLKVATGQMANGGGMMMNFGGMPHQFGGNQQMFQNNQAMQSMLAAHQLQQLQLHPQAQQQQVLHPQHQQQQPLHPLQAQQLQQAARDLKMKSPMGGQSQWGDGKSGSSGN", "length": 380, "molWeight": 40647, "crc64": "1E4865FEA305FF4C", "md5": "DF993A4BD43AF3A7C0E93360CFAB38A8"}}
{"primaryAccession": "Q6AT90", "text": "This is Transcription factor APG protein, from Rice, contains 505 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6AT90", "organism_name": "Rice", "protein_name": "Transcription factor APG", "length": 505, "firstPublicDate": "2014-05-14", "FUNCTION": "Atypical bHLH transcription factor that acts as negative regulator of grain size, Binds the transcription factor ILI6 and forms a heterodimer of antagonistic bHLH transcription factors that regulates grain length and weight by controlling cell elongation in lemma and palea, May be involved in the control of lamina inclination through brassinosteroid signaling pathway", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bHLH protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRGNDTGSDLAELLWDNGAPAPLRPPPPPPFQPFTCSAAATTSPPAHDYLFIKNLMRGGGAANHHHHDDDDDDDDDVPWLHYHPVVDDDDDADADTAPLPPDYCAALLSGLSDHLPPPAAAASRVDPDPCSSSHGAVVPSTSAAAAKQARTSGGGGGGVMNFTFFSRPLQQRPSGGETASASASAAATSTVPVESTVVQAATNRLRSTPLFSDQRMAWLHPPKPSPRAAAPPPPPPLAPTTRHRLDTAAATATVAQRLPPSEARAPDAPPPAATATATTSSVCSGNGDRRQLNWRDSHNNQSAEWSASQDELDLDDELAGVHRRSAARSSKRSRTAEVHNLSERRRRDRINEKMRALQELIPNCNKIDKASMLEEAIEYLKTLQLQVQMMSMGTGMFVPPMMLPAAAAAMQHHHMQMQQMAGPMAAAAHFPHLGAAAAMGLAGFGMPAAAQFPCPMFPAAPPMSMFAPPPPPPPFPHAAATAVEQTPSPPGAADAGNAPAVKQA", "length": 505, "molWeight": 53029, "crc64": "2238FC6CF21B0632", "md5": "958651678851CE1D87EB49E3919C5856"}}
{"primaryAccession": "Q6L6S1", "text": "This is Endoglycoceramidase protein, from Hydra, contains 517 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6L6S1", "organism_name": "Hydra", "protein_name": "Endoglycoceramidase", "length": 517, "firstPublicDate": "2009-12-15", "FUNCTION": "Hydrolysis of the glycosidic linkage between oligosaccharides and ceramides of glycosphingolipids, optimal substrates appear to be the glycosphingolipids with a gangliotetraose structure", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 5 (cellulase A) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MISVALIILFLAKVISGKSDDFISVNPETNMLIDGYGRERFFHGTNVVVKHFPFHPETTGFNKDTFSEDDMKILQKFGLNSIRLGMMLPGYVPKREEYNETYIKVIQSIVTTAAKYGIYTLLDMHQDVFSPKFCVEGMPDWIVNTQGAKDFPMPLHKPFNLDPKTGYPYPEDCAKFSWADYYFTEAAGQAFQNLYDNVDGLRDEWAQFWKKTADVFKEEPSVIGYELINEPFCGNVFKHPTLLIPGVADYLNLQPTYDALQKAIRQVDEEHNIFFEGVTWDFFEVGFTEVPGGKQYQNRSVLSYHYYEPPDFSKKLNFEARLLDLKRLKCGGFLTEMFTVGTDFNSMFEMFDLCDKFKQSWHGWMYKSYGCIEQNLGCLNMSSPGKESIQIANTSRTYPQAVAGRTQSYAFDIKTKVFTLVYETVGSCKSGRTIVYFNKNLHYPNGYRYEINPNFKVTPSENEYFLYLDEVNKVPNTVVTFKLFPLSFTDSEDIHPVTVMGDKHLSENHNENEKKKK", "length": 517, "molWeight": 59685, "crc64": "9042532367D263F4", "md5": "AA59DC9D6331EABEF46C4A564237A55E"}}
{"primaryAccession": "Q6NNI3", "text": "This is Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 1 protein, from Mouse-ear cress, contains 190 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6NNI3", "organism_name": "Mouse-ear cress", "protein_name": "Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 1", "length": 190, "firstPublicDate": "2014-02-19", "FUNCTION": "Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to continuous red (cR), far-red (cFR) and blue (cB) light in a phytochrome-dependent manner, at least during seedling development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the plant homeotic and developmental regulators ALOG protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDLISHQPNKNPNSSTQLTPPSSSRYENQKRRDWNTFCQYLRNHRPPLSLPSCSGAHVLEFLRYLDQFGKTKVHHQNCAFFGLPNPPAPCPCPLRQAWGSLDALIGRLRAAYEENGGPPEANPFGSRAVRLFLREVRDFQAKARGVSYEKKRKRVNRQKPQTQPPLQLQQQQQQPQQGQSMMANYSGATV", "length": 190, "molWeight": 21653, "crc64": "0E2CEB0949FA3A4F", "md5": "DE357250C9C18FEC0A66B120FD8CF6CB"}}
{"primaryAccession": "Q6QZN6", "text": "This is Dapper homolog 1 protein, from Zebrafish, contains 821 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6QZN6", "organism_name": "Zebrafish", "protein_name": "Dapper homolog 1", "length": 821, "firstPublicDate": "2005-12-20", "FUNCTION": "Involved in regulation of intracellular signaling pathways during development, Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins, Binds to dvl2 and may regulate the degradation of ctnnb1/beta-catenin, thereby modulating the transcriptional activation of target genes of the Wnt signaling pathway, Seems to activate the canonical Wnt signaling pathway", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the dapper family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNEWSEMLVCRDYCALMMRDRKECDARCCRDGEGERVRARERLDATVAGLTELEYLRQRQELLVRSVLSCPEAAGQDKPCLTVDDSYLNTEEKLLEENILLLRKQLNCLRRRDAGLINQLQELDRQISDLRLDTETSHEHVETDSRPSSGFYDLSDGASGSLSNSSNSVFSECLSSCRSTTCLCTPLDTSLCASEGRLKPADDPGSCAECDCHCEDSSSGTVRRSLSASYSPSPDSSCDGISKFHCDLIAKNGNDVYRYPSPLHAVAVQSPIFIQSMTSHLKDDCNFSKPGEALNDEQKPEQVVGSQTSSWHASQMLPNKKLDSYIYGLLQRRAQPLRTNKPRTSINTDPSKSILRQASLCSRAPASVQAQQWTSDLKPNWQTCLQDASATSTEPSTASPQRQWSAESKGGTPQNGAYLSSSQPQNSYSTTNENTNCLLKKKVSGTSKGQLLSATPKDCPDLGSPKAVSSPKLNKHCFYNVEDNKTGQAMKASPLKRSPKTQTSLSCGKDSEQLAQELVSLGSSSQSQDEGGPLVSAQYIPAQKQNVNLQKGGTKNIKIVKVKNSASSKSRPQVFEHVSETVRDKHRTGSRRTRQVDEVHHLHKSSKKASAKTKRIPASIPEGRILERHTSSSGARSSAQRHHGHHRHHEAVLAKPKYKRNDFHRRPRGLHEIPYEEAYRRAHRRQKREMLSHMYLPSNAHYTSPYAYVGSDSEYSAECASLFHSTILDTSEDERSNYTTNCFGDSESSASEADYVAESSTSSDSEGSAGVNWRQISQAGSGSHGMTSAQAKAFVKIKASHNLKKKILRFRSGSLKLMTTV", "length": 821, "molWeight": 90721, "crc64": "265F2C7C0A570F4D", "md5": "E3740A9B7320927D42A7009784507C99"}}
{"primaryAccession": "Q6U6J0", "text": "This is Juvenile hormone epoxide hydrolase protein, from Silk moth, contains 461 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6U6J0", "organism_name": "Silk moth", "protein_name": "Juvenile hormone epoxide hydrolase", "length": 461, "firstPublicDate": "2009-11-24", "FUNCTION": "Catalyzes juvenile hormone hydrolysis, Degrades juvenile hormone III (JH III) about 3 times and 5 times slower than juvenile hormone I (JH I) and II (JH II), respectively, Degrades cis-stilbene oxide and trans-stilbene oxide about 18 and 43 times slower than JH III, respectively", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the peptidase S33 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSRLLFIALPLLVLASIPLYLLVLKSPPPMPKLDLEEWWGPPELKQKQDTSIKPFEITFSETMVKELKERIKKRRPFAPPLEGVGFKYGFNSKQLDSWLKYWAEEYPFAERQKFLNQYPHFKTNIQGLNIHFMRITPKVPKDVEIVPLLLLHGWPGSVREFYEAIPHLTAVSRDRNFALEIIAPSLPGYGFSDAAVRPGLAAAEVAVIFKNLMARLGYKQYYVQGGDWGALIGSAMATSFPKEIIGFHSYMALTLSPAATFLEFVGALFPSLIVEPELANRLYPLSEKYSTLLEELGYMHIQATKPDTVGIGLTDSPAGLLAYILEKFSTWTNPDLRSKEDGGLSYRWTKDQLIDNLMLYWSTKSIVTSMRLYAESFSSRHFDLKLDEIQVQVPTWVLQAKHELAYQPPCILKLKYTKLVNASVIEDGGHFLAFELPEIFAKDVLKAIGEFRKLKNVKTEL", "length": 461, "molWeight": 52441, "crc64": "21A6EE19AD54CA57", "md5": "C1494112A0C86C596E9AF8BC26282ACA"}}
{"primaryAccession": "Q704V3", "text": "This is Protein LOL5 protein, from Rice, contains 163 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q704V3", "organism_name": "Rice", "protein_name": "Protein LOL5", "length": 163, "firstPublicDate": "2011-05-31", "FUNCTION": "Involved in plant growth and disease resistance", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSQLPLASQATTTDLVSTTAMQPQSEGIVDESLQPQHPPSSTAHDSPCLQDSVPLVPPPPSPYLNKEVGQMVCGSCRILLAYFRGAGYVHCTCCQTMNYVLEAHEVGKVHCGHCATLLMYPFGAPAVKCSLCLFVTEIGERNVRRRLSIEQPTRTNSSGLAEA", "length": 163, "molWeight": 17575, "crc64": "E5C4569B296D39B3", "md5": "ECE6E99E02BB0B5223985E40482F8EBF"}}
{"primaryAccession": "Q70VB1", "text": "This is G-protein coupled receptor family C group 6 member A protein, from Rat, contains 928 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q70VB1", "organism_name": "Rat", "protein_name": "G-protein coupled receptor family C group 6 member A", "length": 928, "firstPublicDate": "2005-12-06", "FUNCTION": "Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids, The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+), Activated by extracellular calcium and osteocalcin, Seems to act through a G(q)/G(11) and G(i)-coupled pathway, Mediates the non-genomic effects of androgens in multiple tissue, May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MALSFVFITCFMILLDTSQSCHTPDDFVAITSPGHIMIGGLFAIHEKMLSSDDHPRQPQIQKCVGFEISVFLQTLAMIHSIEMINNSSLLSGVKLGYEIYDTCTEVTAAMAATLRFLSKFNCSRETVIFQCDYSSYVPRVKAIIGAGYSEISMAVSRMLNLQLMPQVSYESTAEILSDKIRFPSFLRTVPSDFYQTKAMAHLIRQSGWNWVGAITTDDDYGRLALNTFAIQAAENNVCIAFKEVLPAFLSDNTIEVRINQTLEKIIAEAQVNVIVVFLRKFHVFNLFNKAIERKISKIWIASDNWSTAAKIITIPNVKKLGKVVGFTFRRGNMSSFHSFLQTLHMYPSDNNKPLHEFAMLFSACKHIKDGDLSQCISNYSQATWTYDTTKTIETHLFKRNDFLWHYTEPGLIHSIQLAVLALGHAIRDLCQDRDCQKPNAFQPWELLAVLKNVTFTDGKNSFHFDAHGDLNTGYEVVLWKETNGLMTVTKMAEYDLQHDVFITTNQETKHEFRKLKQILSKCSKECIPGQMKKATGSQHSCCYECVNCPENHYSNETDMDHCLVCNNETHWAPVRSTMCFEKEVEYLDWDDSLALLLIALSLLGIAFVLAVGIIFTRNLKTPVVKSSGGLVVCYVMLACHALNFASTGFFIGEPQDFTCKTRQTLFGVSFTLCVSCILTKSLKILLAFSFDPTLKTFLKCLYRPVPIVLTCTGIQVVICTLWLVLAAPTVEENTSLPRVIILECEEGSALAFGTMLGYIAVLAFICFVFAFKGRKLPENYNEAKFLTFGMLIYFIAWITFIPVYATTFGKYLPAVEIIVILISNYGILCCTFFPKCYIILCKQKTNTKSVFLQMVYNYSAHSVDSLALSHVSLDSASHSTATTNPRPGNKTAACQNYKHLPVQVLAHTGMEKTMHASKTLHQKRSSSI", "length": 928, "molWeight": 104353, "crc64": "0B13BF36E6A60BC4", "md5": "6539E5DEA1AF71DBDCAA4E8F7D9B5CC6"}}
{"primaryAccession": "Q76DI2", "text": "This is Beta-1,3-glucan-binding protein protein, from Yellow mealworm beetle, contains 481 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q76DI2", "organism_name": "Yellow mealworm beetle", "protein_name": "Beta-1,3-glucan-binding protein", "length": 481, "firstPublicDate": "2004-09-27", "FUNCTION": "Involved in the recognition of invading microorganisms, Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the insect beta-1,3-glucan binding protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKVLVVFIFCLVRSTFGQFEVPDALVEVFRPRGLRVSIPDQEGIKLFAFHGKINEEMNGREGGTFSRDILKAKNGRWTFYDANARLKEGDILYYWTYVDYFDGKNKLGYPNDDQKFVVKQLLDKDGAAPSVTPPTVTKAPPQEHTTLESGCKASVTTKVNERVCAGEQIFHEDFTTFETNIWRPEVKFADKPDYEFVFYRAGPPNLQVKHHRLTIRPVPSDAVFGEGFVSRREKVNLAPACTGVHGSIECVQTPGAFLILPPVTSAQISTKGKWSFKYGKVEIRAKLPKGDWIYPELYLNPVNEEYGPGYASGQIRIAFSGGNEDLCRDLRGGCILGSRPAARNYAVKNIVKNSGSWSDDFHKFIVIWKPDQITMMVDDQVYGNIYPPEGGFVSEAYNLDLVNVERWRGGTSFAPFDKEMYLVLGVGVGGHCFEDRSDATKPWTNNDPKSQKKFYQAAAQWGATWSNASRLEVDYVKVSAL", "length": 481, "molWeight": 54075, "crc64": "AAA2CC8B623AECE3", "md5": "EFEBF3583131BBB95F14509F46B1A6F4"}}
{"primaryAccession": "Q7K556", "text": "This is TRPL translocation defect protein 14 protein, from Fruit fly, contains 475 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7K556", "organism_name": "Fruit fly", "protein_name": "TRPL translocation defect protein 14", "length": 475, "firstPublicDate": "2016-04-13", "FUNCTION": "GTP-binding protein which is required for the light-dependent internalization of the TRPL ion channel from the rhabdomere on the apical surface of photoreceptor cells to the cell body and for the recycling of TRPL back to the rhabdomere in the dark, Binds to 3-phosphoinositide (PtdIns(3)P) and phosphatic acid and so may interact with membranes, particularly the early endosome membrane where PtdIns(3)P is predominantly localized, Plays a role in preventing photoreceptor degeneration", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATLLSNGQQSVMASTSNGQEQQRHQDEPEQQQQVEIRKSSSPKPGAMPSLKLNRMGSVSPKDKRVYKIVLTGGPCGGKTTGQSRLCTFFENLGWKVFRVPETATVLLSGGVKFSDLTEKEAYKFQENLIRTMVQIENTYFELGNSSNRNCLIICDRGVMDASAYISKDKWEKMMAGNNWNPVEMRDNRYNQILHLVSAANGAEDFYSTEDHACRSEGVDLARELDYKSAAAWVGHPYFDVIDNSTNFETKMNRMIESVCQKLGIDIGDRLQATSRKLKYLVALLPPDSEFPPFQDFDVVHHYLQSAGPKVQARLRKRGQKNHWSYIHTQRRPNVHGQARIEVKTQLTHRDYMNLLAQRDDAHFTIYKKRRCFLINNQYFQLDIYKEPGHPRCKGLVLLETYSSLTGDALKNCMPKFLNIVKEVTGDPDYSMFNLSLKEDWSTTKKFCRSATHGKQEEQSPVPAKQYHPYDENSD", "length": 475, "molWeight": 54337, "crc64": "261D57E316B51697", "md5": "CB972934A2772D68B7CB0B731088E8F2"}}
{"primaryAccession": "Q7T0L4", "text": "This is Telomeric repeat-binding factor 2-interacting protein 1 protein, from Chicken, contains 329 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7T0L4", "organism_name": "Chicken", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "length": 329, "firstPublicDate": "2010-10-05", "FUNCTION": "Acts both as a regulator of telomere function and as a transcription regulator, Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome), Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2, Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RAP1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAPPRKVFVWEDGTPMRFYIRPGMAKLRLAPLLLAGGAGLCRVQEPGAVHLVQPGEPAPDGAVSTDYVVACVESQRRLPLDLYRHSGPAPLAASPRGRLPFTEAEDAALLRAVRERSGAPRVSGTALWKELECTGLTRHSWQAMRDRYLRHLRPLHRESQQTEEAAAPMGIFEAANREFESSESGSDTSDTPDELPLQNGEGTFPLEAASGLQTGLDDCALPAAQGENKQTNTFSDSSKAEEAAQIIQHFMEEFHTDLLTVTQALLKNSGEVEATSYYLHAGQRLDGYPVWSREDDLELQKDDEDVRSKLIAKFGAENVARRVAFRKS", "length": 329, "molWeight": 36182, "crc64": "0EF989CD7752F3CB", "md5": "FDCA48E4E135DFB3A438157C54AFBC2F"}}
{"primaryAccession": "Q7XA78", "text": "This is Beta-carotene isomerase D27, chloroplastic protein, from Mouse-ear cress, contains 264 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7XA78", "organism_name": "Mouse-ear cress", "protein_name": "Beta-carotene isomerase D27, chloroplastic", "length": 264, "firstPublicDate": "2013-04-03", "FUNCTION": "Involved in strigolactones biosynthesis by catalyzing the isomerization of the C9-C10 double bond in all-trans-beta-carotene leading to 9-cis-beta-carotene and providing the substrate for CCD7, Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNTKLSLSQTKIFTFTTWFNDTRSGLDRRSSISPTLCSKPVYSGKLKAAKETARIETSNTKNASIEDSFFSKIAINYLSKNLQDAAGISSSSKSTDYDRLVDTATRVSRNFDTKQQHEFVLSSLDRALPTVISSLIKMAFPPSKVSRELFALFTTISFAWLVGPSEVRETEVNGRKEKSVVYIEKCRFLEQSNCVGMCTHICKIPSQIFIKNSLGMPIYMEPDFNDLSCKMMFGREPPEIEDDPAMKQPCFEFCKSNKSYGVKH", "length": 264, "molWeight": 29795, "crc64": "50434030D04087BF", "md5": "6D184039D790E1582A3A95F3DC8CED39"}}
{"primaryAccession": "Q7YR83", "text": "This is Epididymal sperm-binding protein 1 protein, from Pig, contains 223 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7YR83", "organism_name": "Pig", "protein_name": "Epididymal sperm-binding protein 1", "length": 223, "firstPublicDate": "2007-10-23", "FUNCTION": "Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation, Has phosphorylcholine-binding activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the seminal plasma protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNRRSSYLLGCTAFILYSYETSGDTKDSCVFPFNYKGFTYFSCTRTNSLSPWCATRAVYDGQWKYCLIEDYPRCVFPFIYRGRSHRNCIVEGSFFGKLWCSVTSSFDEKQQWKYCEINEYGGNSFSKPCIFPSKYRNHIISECLEDESNKLWCPTTENMDMDGKWSLCADTRISSLVPGFPCHFPFNYKNKNYFNCTTKGSKENLLWCATSYNYDQDHTWVYC", "length": 223, "molWeight": 26200, "crc64": "0FCE37524971435C", "md5": "8061061325CF04893EF66FF2E30043E6"}}
{"primaryAccession": "Q7Z2G1", "text": "This is Histone H2B type W-T protein, from Human, contains 175 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7Z2G1", "organism_name": "Human", "protein_name": "Histone H2B type W-T", "length": 175, "firstPublicDate": "2006-07-11", "FUNCTION": "Atypical histone H2B, Nucleosomes containing it are structurally and dynamically indistinguishable from those containing conventional H2B, However, unlike conventional H2B, does not recruit chromosome condensation factors and does not participate in the assembly of mitotic chromosomes, May be important for telomere function", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2B family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRTEVPRLPRSTTAIVWSCHLMATASAMAGPSSETTSEEQLITQEPKEANSTTSQKQSKQRKRGRHGPRRCHSNCRGDSFATYFRRVLKQVHQGLSLSREAVSVMDSLVHDILDRIATEAGHLARSTKRQTITAWETRMAVRLLLPGQMGKLAESEGTKAVLRTSLYAIQQQRK", "length": 175, "molWeight": 19599, "crc64": "9E7C922CAA3FB0B0", "md5": "4F981DBF0E6706333D01DE5F89B7AD02"}}
{"primaryAccession": "Q7Z7J5", "text": "This is Developmental pluripotency-associated protein 2 protein, from Human, contains 298 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7Z7J5", "organism_name": "Human", "protein_name": "Developmental pluripotency-associated protein 2", "length": 298, "firstPublicDate": "2006-05-30", "FUNCTION": "Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSDANLDSSKKNFLEGEVDDEESVILTLVPVKDDANMEQMEPSVSSTSDVKLEKPKKYNPGHLLQTNEQFTAPQKARCKIPALPLPTILPPINKVCRDTLRDWCQQLGLSTNGKKIEVYLRLHRHAYPEQRQDMPEMSQETRLQRCSRKRKAVTKRARLQRSYEMNERAEETNTVEVITSAPGAMLASWARIAARAVQPKALNSCSIPVSVEAFLMQASGVRWCVVHGRLLSADTKGWVRLQFHAGQAWVPTTHRRMISLFLLPACIFPSPGIEDNMLCPDCAKRNKKMMKRLMTVEK", "length": 298, "molWeight": 33784, "crc64": "87FBCCCF52E88B5D", "md5": "4EDB0F76F96A81521391FC45FD378B11"}}
{"primaryAccession": "Q7ZZH7", "text": "This is Protein DBF4 homolog A protein, from African clawed frog, contains 661 amino acids, has 1 DBF4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [269, 317], "description": "DBF4-type", "keyword_description": "Zinc finger", "textural_description": "DBF4-type Zinc finger"}], "meta_data": {"primaryAccession": "Q7ZZH7", "organism_name": "African clawed frog", "protein_name": "Protein DBF4 homolog A", "length": 661, "firstPublicDate": "2008-02-05", "FUNCTION": "Regulatory subunit for cdc7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation, Not required during the initiation of DNA replication in egg and during early embryonic development but is required later and throughout development, The complex cdc7-dbf4a phosphorylates mcm2 subunit", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"DBF4-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKSTVAAVKNPTGKVQADVCKPFTGKLFYLDLTSKLISEKLEKDIKELGGAIEGFLSKEISYLITSKKEAKCVKTLKYVCSIPSPEAAPNTGESSTSPGNRRLCQEGNSSKKNEKSLVSRGKSLVKRAIKEQEILPKNSILSNALNWGVKILHVEEAKHYIEKKKTALQQVRKSQPVVKVESKPQTRRKVKPQKLKSPYIKVEDCSCQYRPLYLVLPQFRSFQNPVSNYSVEVDKKADPGQKLPETKQSVNKTGHGQDGANNPNIKLKEQKKHGYCECCLKKYDDLESHILSPQHKNFSESAYYQVVDDLISTFDFDFVDWSKYKNGRKGVGILMLAEKSKTEGQERNEANLFVSKTHNFSERVTATTPLQENTLKDQHASPCSLPCTPACNADQMFSLPSPAGSARLCNKKYKMDSNFGQLVATPLPSFNLKDSLTGSFGGREMFVAKLNETMEPATEGPKIKWDVCNIPSNISQCIPQKVDPIAQHVNQFPNGNTHCSEMTACQAALIYENVDSAADANIKLPKTVNDLHNKEGHRATDKIYPTVQSHEYLPDYSPSGNLHRKVKTSAHRNKNKDELFCRLSHKVSVPQQEDDSKFPSETLLALFESSEDKTEFFGFAGSPAYESCSMDDGDTPDQTHKKMLLSLFPHTTTSGSSFLGF", "length": 661, "molWeight": 73699, "crc64": "D09D85CBB8B9F274", "md5": "8B2A97498B74676B6DA7442CC4CB5AB1"}}
{"primaryAccession": "Q80WM7", "text": "This is Serine protease 33 protein, from Mouse, contains 277 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q80WM7", "organism_name": "Mouse", "protein_name": "Serine protease 33", "length": 277, "firstPublicDate": "2007-09-11", "FUNCTION": "Serine protease that has amidolytic activity, cleaving its substrates before Arg residues", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGASHLQILLLLVLGTRMQECAACGQPRMSSRIVGGRDAQDGEWPWQTSIQHRGAHVCGGSLIAPQWVLTAGHCFPRRVWPSEYSVLLGALSLDVRSSHELLVPVLRVLLPPDYSEDEARGDLALLQLRHPVSLSTRIQPVCLPAPGSHPPPGSPCWVTGWGSLSPGVPLPKGRPLQGVRVPLLDSRACDRLYHVGANVPQGERIVLPGNLCAGYRRGHKDACQGDSGGPLTCMESGHWVLVGVVSWGKGCALPNRPGVYTNVAKYSPWIQARLSL", "length": 277, "molWeight": 29888, "crc64": "3310C067573E5E74", "md5": "DB070E4132E63013378EBE2D7FC6B0AF"}}
{"primaryAccession": "Q80Z96", "text": "This is Vang-like protein 1 protein, from Mouse, contains 526 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q80Z96", "organism_name": "Mouse", "protein_name": "Vang-like protein 1", "length": 526, "firstPublicDate": "2003-10-31", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Vang family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDTESTYSGYSYYSSHSKKSHRQGERTRERHKSPRNKDGRGSEKSVTIQAPAGEPLLANDSARTGAEEVQDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFILLPQILWREELKPCGAICEGLLISVSFKLLILLIGTWALFFRKQRADVPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDQNYKDIVQYAVSLVDALLFIHYLAIVLLELRQLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRRARLVVAVEEAFIHIQRLQAEEQQKSPGEVMDPREAAQAIFPSMARALQKYLRTTRQQHYHSMESILQHLAFCITNSMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLISEEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIVLSEEFIDPKSHKFVLRLQSETSV", "length": 526, "molWeight": 60064, "crc64": "DCA3CD50A4C0E69A", "md5": "109492CB503143DCDB8F40431E510A69"}}
{"primaryAccession": "Q810U5", "text": "This is Coiled-coil domain-containing protein 50 protein, from Mouse, contains 305 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q810U5", "organism_name": "Mouse", "protein_name": "Coiled-coil domain-containing protein 50", "length": 305, "firstPublicDate": "2005-08-16", "FUNCTION": "Involved in EGFR signaling", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MADVSVDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNIQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKALEQHDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKRRKKHTPEFSGGSVFGDNYYHEDGGMKPRGIKEAVSTPARASHRDQEWYDAEIARKLQEEELLATHVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKHDPECKLKAKSAHSKSKEGDEAHRSKIDRPSRPPPPTMMGLEDTDPTHFTNQHSTTWHLPKSESSQKGFHNKQ", "length": 305, "molWeight": 35321, "crc64": "A49B28050941D82F", "md5": "CECBA0B978E06CB84CDE9B5464C7A416"}}
{"primaryAccession": "Q84L08", "text": "This is GDP-fucose transporter 1 protein, from Mouse-ear cress, contains 341 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84L08", "organism_name": "Mouse-ear cress", "protein_name": "GDP-fucose transporter 1", "length": 341, "firstPublicDate": "2011-03-08", "FUNCTION": "Acts as the major nucleotide-sugar transporter for the import of GDP-Fucose into the Golgi lumen, Transports GDP-Fucose in a strict counter-exchange mode, Is required for proper plant growth and development (PubMed:27381418), Acts also as a GDP-mannose transporter that may be involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen (PubMed:15480787)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the nucleotide-sugar transporter family, GDP-Mannose:GMP antiporter (GMA) (TC 2,A,7,13) subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSSRFDSNKQLTTSSLVIGYALCSSLLAVINKLAITYFNYPGLLTALQYLTCTVAVYLLGKSGLINHDPFTWDTAKKFLPAAIVFYLAIFTNTNLLRHANVDTFIVFRSLTPLLVAIADTVFRSQPLPSRLTFLSLVVILAGAVGYVATDSSFTLTAYSWALAYLVTITTEMVYIKHMVSNIKLNIWGLVLYNNLLSLMIAPVFWFLTGEFTEVFAALSENRGNLFEPYAFSSVAASCVFGFLISYFGFAARNAISATAFTVTGVVNKFLTVVINVLIWDKHATPVGLVCLLFTICGGVGYQQSVKLDKPIEKVSEKDSEKGEEDEELTQLVPGKLASVV", "length": 341, "molWeight": 37386, "crc64": "6952E8F43E57B916", "md5": "82C1F9396A675F54F818031C71667D84"}}
{"primaryAccession": "Q84LG2", "text": "This is bZIP transcription factor 68 protein, from Mouse-ear cress, contains 389 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84LG2", "organism_name": "Mouse-ear cress", "protein_name": "bZIP transcription factor 68", "length": 389, "firstPublicDate": "2016-02-17", "FUNCTION": "Transcriptional activator that binds to the G-box motif (5'-CACGTG-3') and other cis-acting elements with 5'-ACGT-3' core, such as Hex, C-box and as-1 motifs, Possesses high binding affinity to G-box, much lower affinity to Hex and C-box, and little affinity to as-1 element (PubMed:18315949), G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control (Probable), Binds to the G-box motif 5'-CACGTG-3' of LHCB2,4 (At3g27690) promoter, May act as transcriptional activator in light-regulated expression of LHCB2,4, Probably binds DNA as monomer, DNA-binding activity is redox-dependent (PubMed:22718771)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGSSEMEKSGKEKEPKTTPPSTSSSAPATVVSQEPSSAVSAGVAVTQDWSGFQAYSPMPPHGYVASSPQPHPYMWGVQHMMPPYGTPPHPYVTMYPPGGMYAHPSLPPGSYPYSPYAMPSPNGMAEASGNTGSVIEGDGKPSDGKEKLPIKRSKGSLGSLNMIIGKNNEAGKNSGASANGACSKSAESGSDGSSDGSDANSQNDSGSRHNGKDGETASESGGSAHGPPRNGSNLPVNQTVAIMPVSATGVPGPPTNLNIGMDYWSGHGNVSGAVPGVVVDGSQSQPWLQVSDEREIKRQRRKQSNRESARRSRLRKQAECDELAQRAEVLNGENSSLRAEINKLKSQYEELLAENSSLKNKFSSAPSLEGGDLDKNEQEPQRSTRQDVA", "length": 389, "molWeight": 40868, "crc64": "CDFBD3E348BE04CC", "md5": "F32FFA4C3C9E38D5E2101DAB0C6B6933"}}
{"primaryAccession": "Q84N48", "text": "This is CRS2-associated factor 2, chloroplastic protein, from Maize, contains 611 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84N48", "organism_name": "Maize", "protein_name": "CRS2-associated factor 2, chloroplastic", "length": 611, "firstPublicDate": "2007-04-03", "FUNCTION": "Required for the splicing of group IIB introns in chloroplasts, Forms splicing particles with CRS2, Interacts with RNA and confers intron specificity of the splicing particles", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPPPPPQRPASSHVGRANLFSASPPPLSNRRYPHHRSLPLPPVSPRRRDPKKHSQQPSQEEPTDSGPTRTVTTNPAFRAAHLRTAYRKPVPPAAAAGEGEALLAADPTDAASGRAVVVGPSGLSFRLPGAPFDFQFSYSEAPRAPPLAIREPAFLPFAPPTMPRPWTGKAPLLTKEEKARRRGVRLHTPLGQETPQTVSAHGIMMEVRERRKMDLARVSPGDGRSREEVLGEPLTPSEVRALVKPHISHNRQLNIGRDGLTHNMLEMIHCHWRRQEICKVRCRGVPTVDMKNLCYHLEEKSGGKVIHRVGGVVFLYRGRHYDPKTRPRYPLMLWKPATPVYPKLIKEAPDGFTKEEADEMRRKGRDLLPICKLAKNGIYITLVKDVRDAFEGSDLVKIDCEGLNPSDYKKIGAKLRDLVPCVLLSFDDEQILMHRGKEWKSRYSKPLTLIPKVPKNNLAMTSVMNSSDEVSDANTQVAIREVLRPKMFKLWKSAVDSSLALLLDDAEANNLTPDSLLTLVEEFSVTSQAVEHSFPALLVTNGDASTDSLSAEYMNDEPETSVAGNEEGQLEQSPDLRDDEHFDVDMFERLESSVPLGSLPIDSMIERLNSE", "length": 611, "molWeight": 68069, "crc64": "587E44D18160AED7", "md5": "9A7626166094BD4EF45E519A25FA1472"}}
{"primaryAccession": "Q84P17", "text": "This is Probable acyl-activating enzyme 18, peroxisomal protein, from Mouse-ear cress, contains 727 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84P17", "organism_name": "Mouse-ear cress", "protein_name": "Probable acyl-activating enzyme 18, peroxisomal", "length": 727, "firstPublicDate": "2012-02-22", "FUNCTION": "May be involved in the peroxisomal activation of 2,4-dichlorophenoxybutyric acid (2,4-DB), a precursor of active auxins that inhibit root growth", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the ATP-dependent AMP-binding enzyme family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MWKSIGELSCDDYVKAGLTLEDAKEFDKLVSDVITKAIETDPRDQWKALVDESVLKPWHPHPLHQLLYYSVYSNWDSSVHGPPLYWFPSLSQSKSTNLGKLMEYHGPRLLGPSYKNPLESFELFRRFSVEHPEVYWSFVIDELSLVFHTPPRCILNKSKPEGTWLPDAVLNIAECCLMPSSHPKKEDDSVAVVWRNEGFDDSPVNRMTIKELREQVMLVANAISGSFEKGDTIAIDMPMTVDAVIIYLAIILAGCIVVSIADSFAAKEIATRLKISKAKGIFTQDYILRGGRRFPLYSRVVEAAPSKVIVLPASGTELHVQLREQDVSWMDFLSNAKPHSSGENYYRPIYLPVESVINILFSSGTTGEPKAIPWTQLSPIRSACDGWAHLDVQVGHTYCWPTNLGWVMGPTLMFSCFLTGATLALYSGSPLGRGFGKFVQDAGVTVLGTVPSLVKTWKRTNCMEGLNWTKIKFFATTGEASNVDDVLWLSSKADYKPVIECCGGTELASSYIIGSPLQPQAFGAFSTPSMTTRIIIFDENGVPYPDDQPCTGEVGLFPQHLGATDRLLNANHDEVYFKGMPMYKETRLRRHGDIVKRTVGGYYNVQGRADDTMNLGGIKTSSIEIERVCDQADECISETAAVTLTPPNGGPELLVIFAVLKEGFKQQSGEELKMKFSRTIQKDLNPLFKVSFVKIVPEFPRTASSKLLRRVLRDQIKQELLSLRSRI", "length": 727, "molWeight": 81135, "crc64": "3EC1EDDFC040032C", "md5": "4342389DEABA7382B1190E143B23874F"}}
{"primaryAccession": "Q84WL6", "text": "This is Protein WVD2-like 3 protein, from Mouse-ear cress, contains 338 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84WL6", "organism_name": "Mouse-ear cress", "protein_name": "Protein WVD2-like 3", "length": 338, "firstPublicDate": "2016-03-16", "FUNCTION": "Microtubule-associated protein (MAP) that regulates the orientation of interphase cortical microtubules, Binds to, bundles and stabilizes microtubules, Required for the organization and stability of cortical microtubules in hypocotyls, Required for normal hypocotyl cell elongation, Acts as negative regulator of hypocotyl cell elongation in the light", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TPX2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDICMDKEPDGVVVYANGDSCNPNQENVSEPLLDSVSRDDANVHTELRYGEENIEVNEYDVKECTSEIPVGKPIGDDFESKDVTKSSLHAKHASKSGRGNNKTRNTVPQPFSLATEKRASSTRSFTSESLESAGLKKFPDGHSKVQSQATKVPRKPLQPKNKKLSDEEDSCSVASYATSGAKSAKSRTVVTAAPSFRSTERAEKRKEFYTKLEEKHQAMEAEKTQSEARNKEATEAALRQLRKSLRFKANPMPKFYHEGPPPKVELKKPLPTRAKSPKLGRRNPKEGNRAKGASRRHETRKTLVISKEDHDDETTRNADQINHKEMNRNLEPETAFAC", "length": 338, "molWeight": 37782, "crc64": "D04F37188FD67E59", "md5": "4CCA0208D72350BF859D87DAA6564397"}}
{"primaryAccession": "Q84ZT9", "text": "This is Protein WAVE-DAMPENED 2 protein, from Mouse-ear cress, contains 202 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84ZT9", "organism_name": "Mouse-ear cress", "protein_name": "Protein WAVE-DAMPENED 2", "length": 202, "firstPublicDate": "2013-01-09", "FUNCTION": "Microtubule-associated protein (MAP) that regulates the orientation of interphase cortical microtubules, Able to bundle microtubules in vitro, Modulates both rotational polarity and anisotropic cell expansion during organ growth, Promotes clockwise root and etiolated hypocotyls coiling, clockwise leaf curling, but left-handed petiole twisting", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TPX2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRREVFESVSTNASNERVHVAPKIAAEEQDYEEKECTEENSLSQNHKSSNVITENDSKKKNLDEEDDCSVASSMKNAKSKVTHGTAPRFRSAQRAEKRKEYYQKLEEKHQALEAERIELEQRQKEEQEAAIKQLRKNLKFKANPVPDFYYQRPPVKPELKKFPLTRPKSPKLNLSRRKSCSDAITSSGEENSNSQNRQSVVE", "length": 202, "molWeight": 23341, "crc64": "CF8E9D0877ED0A55", "md5": "08C41EC4EDB700DA6FA1D5B91567210A"}}
{"primaryAccession": "Q868T3", "text": "This is Cardioacceleratory peptide receptor protein, from Fruit fly, contains 495 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q868T3", "organism_name": "Fruit fly", "protein_name": "Cardioacceleratory peptide receptor", "length": 495, "firstPublicDate": "2004-08-16", "FUNCTION": "Binds to the cardioactive peptide (CCAP), which is a neuropeptide", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family, Vasopressin/oxytocin receptor subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLHLRLFDSSLYYTLASASESSGLASSTSTERSFNGTQGAGGVAAGGESLTPTDVAAVNLTYFTPAISHVMLAPTTIATTTASATMVQIQTTAAPSHDLETGGNSTSSDPGEFDNLNSFYFYETEQFAVLWILFTVIVLGNSAVLFVMFINKNRKSRMNYFIKQLALADLCVGLLNVLTDIIWRITISWRAGNLACKAIRFSQVCVTYSSTYVLVAMSIDRYDAITHPMNFSKSWKRARHLVAGAWLISALFSLPILVLYEEKLIQGHPQCWIELGSPIAWQVYMSLVSATLFAIPALIISACYAIIVKTIWAKGSIFVPTERAGFGAAPARRASSRGIIPRAKVKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQIPHSQTNIAIATFIQSLAPLNSAANPLIYCLFSSQVFRTLSRFPPFKWFTCCCKSYRNNSQQNRCHTVGRRLHNSCDSMRTLTTSLTVSRRSTNKTNARVVICERPTKVVTVPAMSERV", "length": 495, "molWeight": 54648, "crc64": "28A1AB5C01504716", "md5": "D4ABD1DAD026786D43798CD5C55EB215"}}
{"primaryAccession": "Q86QI5", "text": "This is Defensin protein, from American dog tick, contains 74 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86QI5", "organism_name": "American dog tick", "protein_name": "Defensin", "length": 74, "firstPublicDate": "2003-10-24", "FUNCTION": "Antibacterial activity against Gram-positive and Gram-negative bacteria", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the invertebrate defensin family, Type 2 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGLCICLVFLLVCGLVSATAAAPAESEVAHLRVRRGFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN", "length": 74, "molWeight": 8040, "crc64": "A5A29AF4E70DD0BB", "md5": "E85D6F30243A49BA184BFE12E085C9E5"}}
{"primaryAccession": "Q86QW7", "text": "This is Protein argonaute protein, from Giardia lamblia, contains 781 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86QW7", "organism_name": "Giardia lamblia", "protein_name": "Protein argonaute", "length": 781, "firstPublicDate": "2011-02-08", "FUNCTION": "Plays an essential role in growth and, with Dicer, also involved in microRNA (miRNA)-mediated translational repression, The RNA interference pathway is implicated in antigenic variation having a role in regulation of variant-specific surface protein (VSP)-coding gene expression, Several VSP genes are transcribed but only transcripts encoding the VSP to be expressed accumulate, Antisense RNAs corresponding to the silenced VSP genes are detected", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the argonaute family, Ago subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRNNIAGPPITPVQATVKVTRVRQMDPTDLMSMKILLNILLRRTFESSLGMLNIRSGFYDLRNPSIHAIQIDGRGYDICWIPGFRLTTATLRGKLGLQILPETTKVRSKSMNELLTERRGNIHPSALAVITVMAMHNGKVFRVHSIVQGQTIVSPLANGNETDYFTYYSTRYRDKIDSAGLSLLRHNDYCNSVMQQDKFILKLTPLKRTQNGKVVRPCNVPSSLCIIISDNEIAPYGVSKLSTNRAAVALSTMSPDALLEKATAFAARLAEDTELQSLLGDYGFGFTSNPLELETFVCKPPKLMMDNTSRIVTIEDDSGGVFHNLLQSPGVSPIYYSNNNQPATGMPVWAIMVPRNLGNDYARRLRKELTERVRSLAGTTAPNIGDPPLIAVELSNQRREMYRVEPYKDAFKALLNKLRLEYKDARESEIVAKIQLVVIVIPGPKQDRGDLYKGIKQFYTHMGIVTQCLLAPKSSQNELQWYDQAVLRSVCQQIYAKAGGAVWAPVLPPQNVYSKSTMLCALDISRPKKTVGRPAEVPISTAGFISTYDGSFEYIYSQKKTLVPNRLNHGGELQQQTLMEAFIKNSCNVYLAFNNRILPDHIVIFRDGVSDSQISATLEVEIKSLYECLRQIYHKSNRPMCDLKVIVAQKTCAMRFSAVGGTVLRSGYYVINRSPDNRQQGSEFLMASQAIVHGTTPKPIRYKIIFDSMEASVDNDSFNQLIELTNAMAYGYVNWPQAISLPHVLHMAHHLSKFCGEVLRNGDDLFESCAIFGLQYRPFFI", "length": 781, "molWeight": 87540, "crc64": "8372D20093DF8D6E", "md5": "10D0BB933AA4AADAD9B408A76308CE17"}}
{"primaryAccession": "Q86X83", "text": "This is COMM domain-containing protein 2 protein, from Human, contains 199 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86X83", "organism_name": "Human", "protein_name": "COMM domain-containing protein 2", "length": 199, "firstPublicDate": "2004-08-16", "FUNCTION": "May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237), May down-regulate activation of NF-kappa-B (PubMed:15799966)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLLELSEEHKEHLAFLPQVDSAVVAEFGRIAVEFLRRGANPKIYEGAARKLNVSSDTVQHGVEGLTYLLTESSKLMISELDFQDSVFVLGFSEELNKLLLQLYLDNRKEIRTILSELAPSLPSYHNLEWRLDVQLASRSLRQQIKPAVTIKLHLNQNGDHNTKVLQTDPATLLHLVQQLEQALEEMKTNHCRRVVRNIK", "length": 199, "molWeight": 22745, "crc64": "ECB4B7C26FCEA0F2", "md5": "1F0C5BC5037A1AD3B36BC817EBD8CE28"}}
{"primaryAccession": "Q8AY79", "text": "This is Beta-fibrinogenase stejnefibrase-2 protein, from Chinese green tree viper, contains 258 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8AY79", "organism_name": "Chinese green tree viper", "protein_name": "Beta-fibrinogenase stejnefibrase-2", "length": 258, "firstPublicDate": "2007-07-24", "FUNCTION": "Snake venom serine protease that degrades preferentially beta-chain of fibrinogen (FGB)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Snake venom subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MELIRVLANLLILQLSYAQKSSELVVGGDECNINEHRSLVAIFNSTGFFCSGTLINQEWVVTAAHCDSKNFKMKFGAHSKKLLNEDEQIRNPKEKFICPNKKNNDVLDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSVGSDCRIIGWGSITPIEVTYPDVPYCANINLLDDAECKPGYPELLPEYRTLCAGIVEGGKDTCGGDSGGPLICNGQFHGIVSYGGHPCGQSLKPGIYTKVFDYNDWMKSIIAGNTAATCPP", "length": 258, "molWeight": 28028, "crc64": "2D65C42A30026D28", "md5": "53EBA940CC5F7E7D38B883CA4AC663BE"}}
{"primaryAccession": "Q8AY80", "text": "This is Alpha- and beta-fibrinogenase stejnefibrase-1 protein, from Chinese green tree viper, contains 258 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8AY80", "organism_name": "Chinese green tree viper", "protein_name": "Alpha- and beta-fibrinogenase stejnefibrase-1", "length": 258, "firstPublicDate": "2007-07-24", "FUNCTION": "Snake venom serine protease, Degrades concomitantly alpha- (FGA) and beta-chains of fibrinogen (FGB)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Snake venom subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MELIRVLANLLILQLSYAQKSSELIIGGDECNIDEHRFLVALYKSGRFRCGGTLINQEWVLTAAHCDRRNMEIKLGMHSKNVPNEDEQRRVPKEKFFCDSNKNYTQWNKDIMLIRLNSPVNNSTHIAPLSLPSSPPIVGSVCRIMGWGTITSPNETYPDVPHCANINLFNYTVCHGAHAGLPATSRTLCAGVLEGGKDTCKGDSGGPLICNGQFQGIVSWGGHPCAQPREPGVYTKVFDHLDWIQNIIAGSTTATCPL", "length": 258, "molWeight": 28391, "crc64": "812AE694535255B3", "md5": "E7032DAEDD1033C513F7C841DA4D5584"}}
{"primaryAccession": "Q8BG17", "text": "This is Nucleolar protein 12 protein, from Mouse, contains 217 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BG17", "organism_name": "Mouse", "protein_name": "Nucleolar protein 12", "length": 217, "firstPublicDate": "2007-01-09", "FUNCTION": "May bind to 28S rRNA, In vitro binds single-stranded nucleic acids", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RRP17 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGRNKKKKKRDGDDRRPRLVLNFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLPLPEQGDQDGSQEEEMSSLEKPTKALPRKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRRAQDSTKKPPSATRTSKTQRRRRMTGKARHNGE", "length": 217, "molWeight": 25356, "crc64": "D2CB0564FE6490A7", "md5": "A4F31FF619283E836CE6E13C100BB509"}}
{"primaryAccession": "Q8BGC9", "text": "This is Protein CREG2 protein, from Mouse, contains 288 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BGC9", "organism_name": "Mouse", "protein_name": "Protein CREG2", "length": 288, "firstPublicDate": "2005-02-15", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the CREG family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSLSGRERPAWPGSRLSWLLCCSALLSPAAGYVIVSSVSWAVTNEVDEELDSASTEEALPALLEDSSSIWQQSFPASAHKEDTHLRPRGSARARPAPAARGMFSYRRESGSSEASPGPRVHAGTARSLAHASSWGCLATVSTHEKIQGLPFGSCLAISDGPVHNSTGIPFFYMTAKDPAVADLVKNPTASLVLPESEGEFCRKNIVDPEDPRCARLTLTGRMVTVPPGEVEFAKQAMFSRHPGMRKWPRQYEWFFMKMWVEHIWLQKWYGGVSDIPREEYFKAAPRKA", "length": 288, "molWeight": 31764, "crc64": "A73A97E7BBB1C60E", "md5": "95E6F2A5EBD4476D25FD9D36EA47E832"}}
{"primaryAccession": "Q8BH00", "text": "This is 2-aminomuconic semialdehyde dehydrogenase protein, from Mouse, contains 487 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BH00", "organism_name": "Mouse", "protein_name": "2-aminomuconic semialdehyde dehydrogenase", "length": 487, "firstPublicDate": "2008-01-15", "FUNCTION": "Catalyzes the NAD-dependent oxidation of 2-aminomuconic semialdehyde of the kynurenine metabolic pathway in L-tryptophan degradation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the aldehyde dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAGKRELLMLENFIGGKFLPCNSYIDSYDPSTGEVYCKVPNSGKEEIEAAVEAAREAFPAWSSRSPQERSLVLNRLADVLEQSLEELAQAESKDQGKTLTLARTMDIPRSVLNFRFFASSNLHHVSECTQMSHLGCMHYTVRTPVGIAGLISPWNLPLYLLTWKIAPAIAAGNTVIAKPSEMTSVTAWMFCKLLDKAGVPPGVINIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLEECIPATVRSSFANQGEICLCTSRIFVQRSIYSEFLKRFVEATRKWKVGVPSDPSANMGALISKAHLEKVRSYVLKAQTEGARILCGEGVDQLSLPLRNQAGYFMLPTVITDIKDESRCMTEEIFGPVTCVVPFDSEEEVITRANSVRYGLAATVWSKDVGRIHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITIKY", "length": 487, "molWeight": 53664, "crc64": "5E205A495BD61ED7", "md5": "22AF8EC98710A3B23AF7E2F437F91281"}}
{"primaryAccession": "Q8BHD1", "text": "This is POC1 centriolar protein homolog B protein, from Mouse, contains 476 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BHD1", "organism_name": "Mouse", "protein_name": "POC1 centriolar protein homolog B", "length": 476, "firstPublicDate": "2006-01-24", "FUNCTION": "Plays an important role in centriole assembly and/or stability and ciliogenesis, Involved in early steps of centriole duplication, as well as in the later steps of centriole length control, Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation, Required for primary cilia formation, ciliary length and also cell proliferation, Required for retinal integrity", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the WD repeat POC1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASGLEDPILERSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQGNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSMFRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKMLDLIEGRLIYTLQGHTGPVFTVSFSKDGELLTSGGADAQVLIWRTNFIHLHCKDPKRNLKRLHFEASPHLLDIYPRSPHSHEDRKETIEINPKREVMDLQSSSPPVVDVLSFDSTTMTDSTYRAVPGKGEDICRYFLNPLLMPECSSTTVKKRPEDVSDVPSESLRSVPLAVADALEHIMEQLNILTQTVSILEQRLSLTEDKLRDCLENQQKLFSAVQQKS", "length": 476, "molWeight": 53504, "crc64": "307BF5A63E5F0794", "md5": "29C3E8342C85390BFAED900F1D7718B4"}}
{"primaryAccession": "Q8BJ05", "text": "This is Zinc finger CCCH domain-containing protein 14 protein, from Mouse, contains 735 amino acids, has 5 C3H1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [595, 620], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [621, 640], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [641, 656], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [681, 698], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [700, 718], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "Q8BJ05", "organism_name": "Mouse", "protein_name": "Zinc finger CCCH domain-containing protein 14", "length": 735, "firstPublicDate": "2008-04-29", "FUNCTION": "Involved in poly(A) tail length control in neuronal cells, Binds the polyadenosine RNA oligonucleotides", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ZC3H14 family", "domain_description": {"C3H1-type Zinc finger": 5}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTEPSSLKSPDASIFDSHVPSNKSSFSRGDERRHEAAVPPLAVSSSRPEKRDSRVSTSSQEQKSTNVRHSYDDGASTRLMSTVKPLREPAPSEDVIDIKPEPDDLIDEDLNFVQENPLSQKKPTVTLTYGSSRPSIEIYRPPASRNADTGTHLNRLQLHPQQSSAHAAKQLDVQSSQVSEAGRLCEPPVLSSVEDTYSPFFRNNLDKMSIEDENFRKRKLPVVSSVVKVKRFSHDGEEEEEDEDYGTRIGSLSSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSAVPQKQTLPVAPRTRTSQEELLAEMVQGQNRAPRISPPVKEEEAKGDNTGKSQGTQQRQLLSRLQIDPVMVETMEMSQDYYDMESMVHADTRSFILKKPKLSEEIVVTPNQDSGMKTADALRVLSGHLMQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEEMCFEGMKPVNQTSASNKGLRGLLHPQQLHLLSRQLEDPDGSFSNAEMTDLSVAQKPEKLLERCKYWPACKNGDECVYHHPISPCKAFPNCKFAEKCLFVHPNCKYDTKCTKADCPFTHMSRRASILTPKPVSSPAPSSNGQLCRYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTITVPPRHALKWIRPQSSE", "length": 735, "molWeight": 82409, "crc64": "550696563E7E87C3", "md5": "1CD0911E5774EC19F2AF48565793A35C"}}
{"primaryAccession": "Q8BJM5", "text": "This is Zinc transporter 6 protein, from Mouse, contains 460 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BJM5", "organism_name": "Mouse", "protein_name": "Zinc transporter 6", "length": 460, "firstPublicDate": "2007-12-04", "FUNCTION": "Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway (Probable), As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis (By similarity)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the cation diffusion facilitator (CDF) transporter (TC 2,A,4) family, SLC30A subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGTIHLFRKPQRSFFGKLLQEFRLVAADRRSWKILLFGAINVLCTGFLLMWCSSTNSIALTAYTYLTIFDLFSLITCLISYWVMMRKPSPVYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALSFNLFTMLSIRNKPFAYVSEAASTSWLQEHVADLSRSLCGLIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVSNRLCTLVSTLTVQIFKDDWIRPALSSGPVAPNVLNFSDHHVIPMPLLKNVDERTPVTSTPAKPSSPPPEFSFNTPGKNVSPVILLNTQTRPYSLGLNRGHTPYSSVFSQGLAFPGVGAGQGLRPTFPHIPSRYGINRMGQPRP", "length": 460, "molWeight": 51027, "crc64": "A3E910CE96D16015", "md5": "097E9A3315B7B5723847C1354AF7BD6B"}}
{"primaryAccession": "Q8BT20", "text": "This is Serine protease inhibitor Kazal-type 6 protein, from Mouse, contains 105 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BT20", "organism_name": "Mouse", "protein_name": "Serine protease inhibitor Kazal-type 6", "length": 105, "firstPublicDate": "2005-02-01", "FUNCTION": "Serine protease inhibitor selective for kallikreins, Efficiently inhibits KLK5 and human KLK2, KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14, Doesn't inhibit human KLK1 and KLK8", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKVAGVFLLLSLALLCFFSGAFSQGGQDKRGWITRSEGRFPGKGVLRHRLFQINCGEFRDPKVFCTRESDPLCGSDGQTYGNKCAFCKALEKSSGKINLKHRGKC", "length": 105, "molWeight": 11609, "crc64": "CB59A06715C2C589", "md5": "D355EB1AB0A167A04FE80AA636FF6000"}}
{"primaryAccession": "Q8BTE6", "text": "This is Protein Wfdc21 protein, from Mouse, contains 63 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BTE6", "organism_name": "Mouse", "protein_name": "Protein Wfdc21", "length": 63, "firstPublicDate": "2016-03-16", "FUNCTION": "May promote activation of the metalloproteinase MMP2", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLGAFLLLVSLITLSLEVQELQAAVRPLQLLGTCAELCRGDWDCGPEEQCVSIGCSHICTTN", "length": 63, "molWeight": 6792, "crc64": "A9E69DCE3C825C02", "md5": "3EBF5D0AFA22C4C7C925147310A131C7"}}
{"primaryAccession": "Q8CCG4", "text": "This is Developmental pluripotency-associated protein 4 protein, from Mouse, contains 296 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8CCG4", "organism_name": "Mouse", "protein_name": "Developmental pluripotency-associated protein 4", "length": 296, "firstPublicDate": "2006-05-30", "FUNCTION": "May be involved in the maintenance of active epigenetic status of target genes, May inhibit differentiation of embryonic stem (ES) cells into a primitive ectoderm lineage", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "METAGDKKWSAEEPKEEVELQMSSQPSTAPAKAKATGKKQKKSETDNGCKPKEGKPQDTETPGQTRRKVPIPPIPEYLPPVNLIHRDVLRAWCQKKRVSSKGQKLDAYKRLLARAFPEQMLELRNVPDSAKDARLKTAHKKMKTEPGEESEVTVPLEMVPVPEEQIPALIDPPMLYEEVSTTVVTTPATEAVLASWARIASNAKKYEAVPADASSSSEVKGEMWCVVHGTSLPGNSRGWVRLQFHAGQAWVPDKKGKAIALFLLPACTFPPPHLEDNMLCPKCVHKNKILTKSLEG", "length": 296, "molWeight": 32699, "crc64": "31CADF37547975B2", "md5": "C3C30BF5266F2A93A9A1CAF787D557C2"}}
{"primaryAccession": "Q8CG85", "text": "This is MAM domain-containing protein 2 protein, from Mouse, contains 686 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8CG85", "organism_name": "Mouse", "protein_name": "MAM domain-containing protein 2", "length": 686, "firstPublicDate": "2004-04-13", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLLEGVLLVVQALQLASALDLPAGSCAFEEDTCGFDSVFAFLPWILNEEGHYVYMDTSFARQGEKAVLLSSDLQAEEWNCLRLVYQITTPPGSVSDPSQLNLYVRFEDESFDRLLWSTKEPSDSWLIASLDLQNTSKKFKILIEGVLGQGNTASIALFEIKMTAGYCIECDFEENHLCGFVNRWNPNVNWFVGGGTAKNTHSVLPQDHTFRSEHGHYMYVDSVYVKHFQEVAQLISPVTTASMSGCLSFYYQLQQGNDNVFSVYTRDMAGLYEEIWKVDSPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTGLPFSAVETSCDFEIGLCNFYQDKEGPGWTRVRVKANMYRAGDHTTGTGHYLLANTKFTSQPGYIGRLYGPSLPGNMQYCVRFHYAIFGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEISFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGNCRSPARLPPPPGECTFDQDECAFTQEKRNRSSWHRGRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKAHLLSQPLRGVPGKHCLTFFYHMYGAGTGLLSVYLKREEDSEESLLWRRRGEQSISWLRALVEYSCRRRHQIIFEATRGVSIRSDIAIDDVKLQAGPCAGMEDTTEQSSGYSEDLNEIEY", "length": 686, "molWeight": 77324, "crc64": "C276B12A90226EAC", "md5": "994A9B84A99844B9B248AB160A2D6615"}}
{"primaryAccession": "Q8GSI0", "text": "This is Protein TIFY 11a protein, from Rice, contains 179 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GSI0", "organism_name": "Rice", "protein_name": "Protein TIFY 11a", "length": 179, "firstPublicDate": "2015-12-09", "FUNCTION": "Repressor of jasmonate (JA) responses, Forms a ternary complex with RSS3 and BHLH94 to negatively regulate JA-responsive genes (PubMed:23715469), Acts as positive regulator of tolerance to salt stress (PubMed:19618278, PubMed:25617318), Involved in salt tolerance by modulating potassium homeostasis through JA signaling and regulation of the expression of potassium ion transporter genes, Acts as a transcriptional regulator targeted by the SCF(COI1) E3 ubiquitin ligase complexes in the JA signaling pathway, and interacts with BHLH062 that may directly regulate the ion transporter genes (PubMed:25617318), Acts as positive regulator of tolerance to dehydration stress (PubMed:19618278), Acts as negative regulator of tolerance to cold stress by interacting with MYB30 (PubMed:28062835)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TIFY/JAZ family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASTDPMTRRFAVACGVLSQYVKANSSQPSTAAPVAQGVSGLMAAAAAAAAAPVVQEPGCEVDGGGQQFTIFYAGKVVVIDRCTPAMAAELMRFASAAQGGGGAPEAPPALVDMPIARKASLKRFLAKRKATPASARSSYVVRAAAAEEEQPPAKKAKAAVERREDWLALGSLGHMHSR", "length": 179, "molWeight": 18395, "crc64": "1A14781E2D4573B4", "md5": "2784C950F1518B3AA79D03E3E5A1C7D6"}}
{"primaryAccession": "Q8GVZ6", "text": "This is Protein G1 protein, from Rice, contains 276 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GVZ6", "organism_name": "Rice", "protein_name": "Protein G1", "length": 276, "firstPublicDate": "2014-02-19", "FUNCTION": "Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity), Transcription regulator that restrains empty glumes growth, lemmas of the sterile florets located at the lateral side of the rice spikelet, to maintain their small size, probably by repressing lemma identity via transcription regulation", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the plant homeotic and developmental regulators ALOG protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSSSAAALGSDDGCSPAELRPSRYESQKRRDWQTFTQYLAAHRPPLELRRCSGAHVLEFLRYLDRFGKTRVHEPPCPSYGGRSPSAAGPVAAAAAACQCPLRQAWGSLDALVGRLRAAYDERHGRAGEPDAVAGAGAVATDSTSSSSAAAANPFAARAVRLYLRDVRDAQAMARGISYHKKKKRRGGNMNGARGGGGGGARAGVNDGDATAPPVAVTPGLPLPPLPPCLNGVPFEYCDFGSVLGGAHGAHGGHGGGGGGFYGAGVYLPFLYNTFS", "length": 276, "molWeight": 28497, "crc64": "B390385113BFCE6D", "md5": "146BDA99E4A47FC28E1AAF9B1FC2B6C8"}}
{"primaryAccession": "Q8GYX9", "text": "This is Protein WVD2-like 1 protein, from Mouse-ear cress, contains 286 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GYX9", "organism_name": "Mouse-ear cress", "protein_name": "Protein WVD2-like 1", "length": 286, "firstPublicDate": "2013-01-09", "FUNCTION": "Microtubule-associated protein (MAP) that regulates the orientation of interphase cortical microtubules, Modulates both rotational polarity and anisotropic cell expansion during organ growth, Promotes clockwise root and etiolated hypocotyls coiling, clockwise leaf curling, but left-handed petiole twisting", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TPX2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGREVVEVLMDRNADVSSARVHVAPKIAAEETDEEFEVKECTEEKSLSENAPNVGSAERVGAQKSPKTRNGNAKVSKQDAPLLAVRKPLQPENKKHIDDEDNCSIASSVATSMRMGKSGLTYGSAPTFRSAQRAEKRKEYYQKLEEKNQALEAERNELEQRQKDEQEAALKQLRKNLKFKAKPVPNFYYEAPPAKPELKKLPLTRPKSPKLILSRRKSFSDAVSSSSREEILKTVSNRNRHSTGTVQNKDDDHRNKNTNAAHDSPRVRSGKGKSGLKPVNESSEEA", "length": 286, "molWeight": 31950, "crc64": "4DDE02C3573CC7E0", "md5": "9EB9DDC5D00D72ADB4EBC89BF08F9C16"}}
{"primaryAccession": "Q8I948", "text": "This is Acanthoscurrin-1 protein, from Tarantula spider, contains 156 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8I948", "organism_name": "Tarantula spider", "protein_name": "Acanthoscurrin-1", "length": 156, "firstPublicDate": "2004-09-27", "FUNCTION": "Antimicrobial protein, Strong activity against the Gram-negative bacterium E,coli SBS363 and yeast C,albicans, No detectable activity against the Gram-positive bacterium M,luteus", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFRMKLVVCIVLLSTLAVMSSADVYKGGGGGRYGGGRYGGGGGYGGGLGGGGLGGGGLGGGKGLGGGGLGGGGLGGGGLGGGGLGGGKGLGGGGLGGGGLGGGGLGGGGLGGGKGLGGGGLGGGGLGGGRGGGYGGGGGYGGGYGGGYGGGKYKG", "length": 156, "molWeight": 12749, "crc64": "90FC3C9F663E9D4B", "md5": "D2F53EFD4885D6412BC4771188E76925"}}
{"primaryAccession": "Q8IN43", "text": "This is Protein Turandot C protein, from Fruit fly, contains 129 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IN43", "organism_name": "Fruit fly", "protein_name": "Protein Turandot C", "length": 129, "firstPublicDate": "2008-11-25", "FUNCTION": "A humoral factor that may play a role in stress tolerance", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the Turandot family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNASISLLCLALLLISPFCLGYSDEERESDSLRVAEIIRTSNDAESKINRTQELLDIFRRLTPTLSPEQREKIERSIQEHTDEILIDGVPSQGGRKTKYVGKILSPVAQGLAVGFFEELGGSLSRLFTG", "length": 129, "molWeight": 14296, "crc64": "4078FF39507B0D0A", "md5": "79C91D7AD4883A465E0FD167AEBE75CD"}}
{"primaryAccession": "Q8IZS7", "text": "This is Putative C-type lectin-like domain family 1 protein, from Human, contains 167 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IZS7", "organism_name": "Human", "protein_name": "Putative C-type lectin-like domain family 1", "length": 167, "firstPublicDate": "2008-02-05", "FUNCTION": "May function in mediating immune cell-cell interactions, May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation, May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVSNFFHVIQVFEKSATLISKTEHIGFVIYSWRKSTTHLGSRRKFAISIYLSEVSLQKYDCPFSGTSFVVFSLFLICAMAGDVVYADIKTVRTSPLELAFPLQRSVSFNFSTVHKSCPAKDWKVHKGKCYWIAETKKSWNKSQNDCAINNSYLMVIQDITAMVRFNI", "length": 167, "molWeight": 19115, "crc64": "581A6F08DB32A53C", "md5": "3D798B4F6E1376BD1F88A18BED27A464"}}
{"primaryAccession": "Q8IZT9", "text": "This is Protein FAM9C protein, from Human, contains 166 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IZT9", "organism_name": "Human", "protein_name": "Protein FAM9C", "length": 166, "firstPublicDate": "2003-03-25", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the FAM9 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAKDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD", "length": 166, "molWeight": 19210, "crc64": "247460DA7E86FB66", "md5": "E1C4C3D0E8765BFB057C38455EB79C1E"}}
{"primaryAccession": "Q8K0T0", "text": "This is Reticulon-1 protein, from Mouse, contains 780 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8K0T0", "organism_name": "Mouse", "protein_name": "Reticulon-1", "length": 780, "firstPublicDate": "2005-03-15", "FUNCTION": "Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAPPDLQDEPLSLGSPGSQWFGGRGDGEDEATAVMGARPAQQDGEPAWGSGAGAGVTSSRELCSGPARSPPVAMETASTGMAAVPDALDHSPSSTLKDGEGACYTSLISDVCYPPREDSAYFTGILQKENGHITTSESPEEPETPGPSLPEVPGMEPQGLLSSDSGIEMTPAESTEVNKILADPLDQMKAEAYKYIDITRPQEAKGQEEQHPGLEDKDLDFKDKDTEVSTKAEGVRAPNQPAPVEGKLIKDHLFEESTFAPYIDELSDEQHRVSLVTAPVKITLTEIEPPLMTATQETIPEKQDLCLKPSPDTVPTVTVSEPEDDSPGSVTPPSSGTEPSAAESQGKGSVSEDELIAAIKEAKGLSYETTESPRPVGQVADKPKTKTRSGLPTIPSPLDQEASSAESGDSEIELVSEDPMASEDALPSGYVSFGHVSGPPPSPASPSIQYSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPGALDAIREETGSRATEERAPSHQGPVEPDPMLSFAPAAALQSRPEPSSGDGASVPEPPRSQQQKPEEEAVSSSQSPTATEIPGPLGSGLMPPLPFFNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQLYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQVDQYLGLVRTHINTVVAKIQAKIPGAKRHAE", "length": 780, "molWeight": 83572, "crc64": "29B47A58FC2F2027", "md5": "5C03696D1C03E4CF913A8347215D3101"}}
{"primaryAccession": "Q8K3W2", "text": "This is Leucine-rich repeat-containing protein 10 protein, from Mouse, contains 274 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8K3W2", "organism_name": "Mouse", "protein_name": "Leucine-rich repeat-containing protein 10", "length": 274, "firstPublicDate": "2005-09-27", "FUNCTION": "May play important roles in cardiac development and/or cardiac function", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGNTIRAFVAFIPTDRCQSYVVGDLREMPLDRMVDLSGSQLRRFPLHVCSFTELVKLYLSDNHLHSLPPDLAQLQNLQILALDFNNFKALPRVVCTLKQLCILYLGNNKLCDLPDELSLLQNLRTLWLESNCLTRLPDVVCELSLLKTLHAGSNALRLLPGQLRRLRELRTIWLSGNQLADFPSVLLRMPFLEVIDVDRNSIRYFPSLAHLTNLKLVIYDHNPCRNAPKVGKGVRRVGRWAEETPEPDPRKARRYALAKEENQEPPPPLLPSSS", "length": 274, "molWeight": 31263, "crc64": "826B76D4FA4EDDD0", "md5": "DFBECD71AB30ED77FB8C16094A21A77C"}}
{"primaryAccession": "Q8K4I4", "text": "This is BPI fold-containing family A member 1 protein, from Rat, contains 270 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8K4I4", "organism_name": "Rat", "protein_name": "BPI fold-containing family A member 1", "length": 270, "firstPublicDate": "2003-08-29", "FUNCTION": "Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC), Plays a role in the innate immune responses of the upper airways, Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P,aeruginosa and K,pneumoniae, Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus, Plays a role in the airway inflammatory response after exposure to irritants, May attract macrophages and neutrophils", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the BPI/LBP/Plunc superfamily, Plunc family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFLVGSLVVLCGLLAQSTAQLAGLPLPLGQGLPLPLGQGLPLPLGQGLPLAVSPALPSNPTDLLAGNFANALSGGLLSGGLLGILENIPLLDVIKSGGGSSNGLVGGLLGKLTSSVPLLNNILDIKITDPRLLELGLVQSPDGHRLYATIPLSLKLQVNMPVVGSFLQLAVKLNITAEIVAMKDNQGRIHLVLGDCTHSPGSLQITLLNGVTPVQSSLDSLTGILTKVLPELIQGKVCPLINGILSGLDVTLVHNIAELLIHGIQFVIKV", "length": 270, "molWeight": 27719, "crc64": "17B5EA3D4C845524", "md5": "6BC6D889B16D2EF82F3D5EF2C9C26F18"}}
{"primaryAccession": "Q8L735", "text": "This is Isoamylase 2, chloroplastic protein, from Mouse-ear cress, contains 882 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8L735", "organism_name": "Mouse-ear cress", "protein_name": "Isoamylase 2, chloroplastic", "length": 882, "firstPublicDate": "2009-07-07", "FUNCTION": "Involved in the trimming of pre-amylopectin chains, Accelerates the crystallization of nascent amylopectin molecules during starch synthesis, ISA1 and ISA2 work exclusively together as a multimeric holoenzyme, ISA1-ISA2 removes preferentially branches that are very close to other branches", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the glycosyl hydrolase 13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAWSPSVGIGSCCLNNGITRTWKFPSARLFTGRKNKIKLGSETLMFTRKRFMGDLVTSALQSYQFSKICASKTSIELREALSSRRAEADDLKKVTSYSFRTKAGALVKVKVEKKREKYSILVYVSSLELSGDDKSRLVMVWGVYRSDSSCFLPLDFENSSQDSQTHTTETTFVKSSLSELMLGLEFDGKESPFYLSFHLKLVSGRDPDGQEMLTHRDTDFCIPVGFTAGHPLPLGLSSGPDDDSWNFSFFSRSSTNVVLCLYDDSTTDKPALELDLDPYVNRTGDVWHASVDNTWDFVRYGYRCKETAHSKEDVDVEGEPIVLDPYATVVGKSVSQKYLGSLSKSPSFDWGEDVSPNIPLEKLLVYRLNVKGFTQHRSSKLPSNVAGTFSGVAEKVSHLKTLGTNAVLLEPIFSFSEQKGPYFPFHFFSPMDIYGPSNSLESAVNSMKVMVKKLHSEGIEVLLEVVFTHTADSGALRGIDDSSYYYKGRANDLDSKSYLNCNYPVVQQLVLESLRYWVTEFHVDGFCFINASSLLRGVHGEQLSRPPLVEAIAFDPLLAETKLIADCWDPLEMMPKEVRFPHWKRWAELNTRYCRNVRNFLRGRGVLSDLATRICGSGDVFTDGRGPAFSFNYISRNSGLSLVDIVSFSGPELASELSWNCGEEGATNKSAVLQRRLKQIRNFLFIQYISLGVPVLNMGDECGISTRGSPLLESRKPFDWNLLASAFGTQITQFISFMTSVRARRSDVFQRRDFLKPENIVWYANDQTTPKWEDPASKFLALEIKSESEEEETASLAEPNEPKSNDLFIGFNASDHPESVVLPSLPDGSKWRRLVDTALPFPGFFSVEGETVVAEEPLQQLVVYEMKPYSCTLFETINTTA", "length": 882, "molWeight": 98884, "crc64": "277940176F03B06D", "md5": "45D05CE975EF54CF71318F5F966E5FD9"}}
{"primaryAccession": "Q8LCT3", "text": "This is Thioredoxin-like 2-2, chloroplastic protein, from Mouse-ear cress, contains 236 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LCT3", "organism_name": "Mouse-ear cress", "protein_name": "Thioredoxin-like 2-2, chloroplastic", "length": 236, "firstPublicDate": "2004-09-13", "FUNCTION": "Thiol-disulfide oxidoreductase that may participate in various redox reactions, Possesses insulin disulfide bonds reducing activity", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the thioredoxin family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGVVRLTTTSVQAIRVSSSFSSFATALNPLQPCLPPNSNLNSDKRLRLLSSSPSCSSSHYHPSSGLGSHLPLRRPKSQVVRVKVDENVAETEPPKWWERNAPNMVDIHSTEEFLSALSGAGERLVIVEFYGTWCASCRALFPKLCKTAVEHPDIVFLKVNFDENKPMCKSLNVRVLPFFHFYRGADGQLESFSCSLAKVKKAISVSPFPQLELGITLQTKRTTSLFFFDRIYQIL", "length": 236, "molWeight": 26337, "crc64": "7279192F2BF2A391", "md5": "39FC1B454AD2170552437BAF4BB08C95"}}
{"primaryAccession": "Q8LFH6", "text": "This is Actin-depolymerizing factor 12 protein, from Mouse-ear cress, contains 137 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LFH6", "organism_name": "Mouse-ear cress", "protein_name": "Actin-depolymerizing factor 12", "length": 137, "firstPublicDate": "2007-02-20", "FUNCTION": "Actin-depolymerizing protein, Severs actin filaments (F-actin) and binds to actin monomers", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the actin-binding proteins ADF family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MANAASGMAVEDECKLKFLELKAKRNYRFIIFRIDGQQVVVEKLGSPQENYDDFTNYLPPNECRYAVYDFDFTTAENIQKSKIFFIAWSPDSSRVRMKMVYASSKDRFKRELDGIQVELQATDPSEMSLDIIKSRAL", "length": 137, "molWeight": 15884, "crc64": "0E5DB2C913CADE3F", "md5": "F0C6EBF488D182E62BABB45A1887C7F5"}}
{"primaryAccession": "Q8LFP9", "text": "This is Protein ABA DEFICIENT 4, chloroplastic protein, from Mouse-ear cress, contains 220 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LFP9", "organism_name": "Mouse-ear cress", "protein_name": "Protein ABA DEFICIENT 4, chloroplastic", "length": 220, "firstPublicDate": "2016-04-13", "FUNCTION": "Required for neoxanthin biosynthesis, an intermediary step in abscisic acid (ABA) biosynthesis, Probably not involved directly in the enzymatic conversion of violaxanthin to neoxanthin, Cannot convert violaxanthin to neoxanthin in vitro, Required for ABA biosynthesis in response to drought stress (PubMed:17470058), Required for neoxanthin biosynthesis which is involved in photoprotection of photosystem II (PSII), Neoxanthin acts as an antioxidant within the photosystem PSII supercomplex (PubMed:17351115)", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGFSSFISQPLSSSLSVMKRNVSAKRSELCLDSSKIRLDHRWSFIGGSRISVQSNSYTVVHKKFSGVRASWLTTTQIASSVFAVGTTAVLPFYTLMVVAPKAEITKKCMESSVPYIILGVLYVYLLYISWTPETLKYMFSSKYMLPELSGIAKMFSSEMTLASAWIHLLVVDLFAARQVYNDGLENQIETRHSVSLCLLFCPVGIVSHFVTKAIINNQYK", "length": 220, "molWeight": 24624, "crc64": "0286CA46945F93C1", "md5": "D2EA53A107429ACA79B9655C4FB656CD"}}
{"primaryAccession": "Q8LG77", "text": "This is Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial protein, from Mouse-ear cress, contains 374 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LG77", "organism_name": "Mouse-ear cress", "protein_name": "Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial", "length": 374, "firstPublicDate": "2007-01-09", "FUNCTION": "Catalytic subunit of the NAD(+)-dependent isocitrate dehydrogenase involved in the oxidative decarboxylation of isocitrate to 2-oxoglutarate (Probable), Performs an essential role in the oxidative function of the citric acid cycle", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTMTAFLARRLIGNGSSQILGTSSSSSGPFISVSRAFFSSSTPIKATLFPGDGIGPEIAESVKQVFTAADVVIDWDEQFVGTEVDPRTNSFLTWDNLQSVLKNKVGLKGPMATPIGKGHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVDLITIRENTEGEYSGLEHQVVKGVVESLKIITRKASMRVAEYAFLYAKTHGRKKVSAIHKANIMQKTDGLFLQCCDEVAAKYPEIYYEKVVIDNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLVGGLGLTPSMNIGEDGIALAEAVHGSAPDIAGMNLANPTALLLSGVMMLRHLKLNKQAEQIHSAIINTIAEGKYRTADLGGSSTTTDFTKAICDHL", "length": 374, "molWeight": 40576, "crc64": "3587127E0EAB87A4", "md5": "B7B3FE6C69C85D36BA1A9F9ED0A30B4A"}}
{"primaryAccession": "Q8N0S6", "text": "This is Centromere protein L protein, from Human, contains 344 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8N0S6", "organism_name": "Human", "protein_name": "Centromere protein L", "length": 344, "firstPublicDate": "2006-07-25", "FUNCTION": "Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation, May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CENP-L/IML3 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDSYSAPESTPSASSRPEDYFIGATPLQKRLESVRKQSSFILTPPRRKIPQCSQLQEDVDPQKVAFLLHKQWTLYSLTPLYKFSYSNLKEYSRLLNAFIVAEKQKGLAVEVGEDFNIKVIFSTLLGMKGTQRDPEAFLVQIVSKSQLPSENREGKVLWTGWFCCVFGDSLLETVSEDFTCLPLFLANGAESNTAIIGTWFQKTFDCYFSPLAINAFNLSWMAAMWTACKMDHYVATTEFLWSVPCSPQSLDISFAIHPEDAKALWDSVHKTPGEVTQEEVDLFMDCLYSHFHRHFKIHLSATRLVRVSTSVASAHTDGKIKILCHKYLIGVLAYLTELAIFQIE", "length": 344, "molWeight": 38998, "crc64": "20EB5565F392FDE2", "md5": "C663BFF9EA8B614FF1A4402346CA315C"}}
{"primaryAccession": "Q8R400", "text": "This is Adipogenin protein, from Mouse, contains 80 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8R400", "organism_name": "Mouse", "protein_name": "Adipogenin", "length": 80, "firstPublicDate": "2007-07-24", "FUNCTION": "Plays a role in stimulating adipocyte differentiation and development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the adipogenin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKYPLVPLVSDLTLSFLVFWLCLPVALLLFLTIVWLHFLLSQESKEDDSDLCFNWEPWSKRPSECGCEETFPGEEDGLHW", "length": 80, "molWeight": 9362, "crc64": "C0DC97A0EF6C37BD", "md5": "6F7F583430839FCD8585E25F719A0CBC"}}
{"primaryAccession": "Q8RXL8", "text": "This is UDP-xylose transporter 3 protein, from Mouse-ear cress, contains 357 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8RXL8", "organism_name": "Mouse-ear cress", "protein_name": "UDP-xylose transporter 3", "length": 357, "firstPublicDate": "2007-09-11", "FUNCTION": "Nucleotide-sugar transporter that transports UDP-xylose and UMP in a strict counter-exchange mode", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the TPT transporter family, TPT (TC 2,A,7,9) subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSEGQKFQLGTIGALSLSVVSSVSIVICNKALISTLGFTFATTLTSWHLLVTFCSLHVALWMKMFEHKPFDPRAVMGFGILNGISIGLLNLSLGFNSVGFYQMTKLAIIPCTVLLETLFFRKKFSRKIQFSLTILLLGVGIATVTDLQLNMLGSVLSLLAVVTTCVAQIMTNTIQKKFKVSSTQLLYQSCPYQAITLFVTGPFLDGLLTNQNVFAFKYTSQVVFFIVLSCLISVSVNFSTFLVIGKTSPVTYQVLGHLKTCLVLAFGYVLLRDPFDWRNILGILVAVIGMVVYSYYCSIETQQKASETSTQLPQMKESEKDPLIAAENGSGVLSDGGGGVQQKTVAPVWNSNKDFQA", "length": 357, "molWeight": 39038, "crc64": "10F5861948D40D9C", "md5": "8858D39D5F4442D35E3569313B8C2304"}}
{"primaryAccession": "Q8SPJ0", "text": "This is Inactive ribonuclease-like protein 10 protein, from Pig, contains 213 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8SPJ0", "organism_name": "Pig", "protein_name": "Inactive ribonuclease-like protein 10", "length": 213, "firstPublicDate": "2006-02-07", "FUNCTION": "Secreted proximal epididymal protein required for post-testicular sperm maturation and male fertility, May be involved in sperm adhesion to the egg zona pellucida (By similarity), Does not have ribonuclease activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the pancreatic ribonuclease family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLTLVQFFFMMLLLLLGLGVGLGLGLQMAAAVLEESDQLLSEFQSSDSQDKTQATKKGAGTRTMETLLLSDNVVMQPEETILSEDEVGGNKMLRAQAFSQSYPNYLRSDLMDRECNTLMAKKMKPYNHTCISQYIFIHEEPDEIKAVCKSPPVACELKGGKCHKSARPFDLTFCKLSKPGQVTPHCNYVTFLLEKHILISCNDMKVQVMSGS", "length": 213, "molWeight": 23740, "crc64": "515ADA0B39A1AF02", "md5": "29D5E2B8CDF36979FBF270D248BA5252"}}
{"primaryAccession": "Q8T0W8", "text": "This is Diapause-specific peptide protein, from Leaf beetle, contains 65 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8T0W8", "organism_name": "Leaf beetle", "protein_name": "Diapause-specific peptide", "length": 65, "firstPublicDate": "2002-11-15", "FUNCTION": "Has antifungal activity against T,rubrum, Blocks voltage-dependent N-type calcium channels (Cav2,2 / CACNA1B)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the diapausin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGAALKMTIFLLIVACAMIATTEAAVRIGPCDQVCPRIVPERHECCRAHGRSGYAYCSGGGMYCN", "length": 65, "molWeight": 6939, "crc64": "72BC929D4AA31A42", "md5": "5CF6192DA283BBD28C7E46D6DFC980EB"}}
{"primaryAccession": "Q8TBE7", "text": "This is Solute carrier family 35 member G2 protein, from Human, contains 412 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8TBE7", "organism_name": "Human", "protein_name": "Solute carrier family 35 member G2", "length": 412, "firstPublicDate": "2006-06-27", "FUNCTION": "May play a role in cell proliferation", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the SLC35G solute transporter family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDTSPSRKYPVKKRVKIHPNTVMVKYTSHYPQPGDDGYEEINEGYGNFMEENPKKGLLSEMKKKGRAFFGTMDTLPPPTEDPMINEIGQFQSFAEKNIFQSRKMWIVLFGSALAHGCVALITRLVSDRSKVPSLELIFIRSVFQVLSVLVVCYYQEAPFGPSGYRLRLFFYGVCNVISITCAYTSFSIVPPSNGTTMWRATTTVFSAILAFLLVDEKMAYVDMATVVCSILGVCLVMIPNIVDEDNSLLNAWKEAFGYTMTVMAGLTTALSMIVYRSIKEKISMWTALFTFGWTGTIWGISTMFILQEPIIPLDGETWSYLIAICVCSTAAFLGVYYALDKFHPALVSTVQHLEIVVAMVLQLLVLHIFPSIYDVFGGVIIMISVFVLAGYKLYWRNLRKQDYQEILDSPIK", "length": 412, "molWeight": 46422, "crc64": "94EB36A60A83355D", "md5": "30C34BD5FDB444D3A1C34A46380BE997"}}
{"primaryAccession": "Q8TCB6", "text": "This is Olfactory receptor 51E1 protein, from Human, contains 317 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8TCB6", "organism_name": "Human", "protein_name": "Olfactory receptor 51E1", "length": 317, "firstPublicDate": "2003-10-10", "FUNCTION": "Odorant receptor", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVDPNGNESSATYFILIGLPGLEEAQFWLAFPLCSLYLIAVLGNLTIIYIVRTEHSLHEPMYIFLCMLSGIDILISTSSMPKMLAIFWFNSTTIQFDACLLQMFAIHSLSGMESTVLLAMAFDRYVAICHPLRHATVLTLPRVTKIGVAAVVRGAALMAPLPVFIKQLPFCRSNILSHSYCLHQDVMKLACDDIRVNVVYGLIVIISAIGLDSLLISFSYLLILKTVLGLTREAQAKAFGTCVSHVCAVFIFYVPFIGLSMVHRFSKRRDSPLPVILANIYLLVPPVLNPIVYGVKTKEIRQRILRLFHVATHASEP", "length": 317, "molWeight": 35271, "crc64": "8C7293AA7FBCA95C", "md5": "1972D36A07456C9E36FCA49CAF377AEE"}}
{"primaryAccession": "Q8VYE2", "text": "This is Mitochondrial import inner membrane translocase subunit TIM50 protein, from Mouse-ear cress, contains 376 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VYE2", "organism_name": "Mouse-ear cress", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM50", "length": 376, "firstPublicDate": "2005-12-06", "FUNCTION": "Essential component of the TIM17:23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the TIM50 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASIVLRSRLLPRLAKLRSRNLRCFSAEASSTNSTSRYSGVTSTQSMFSDFPPPNQPPPPPPPQVEAAAAAATGKERKGLKYLGYALLWALTGATAATGYASFAYTIDEVNEKTKAFRESATKTPVIKSSGIDVIDKYQTKLYSAAMTGSARAIDKYLELREIVEEQVKGFTEPLSEKLLPDLHPAEQHVFTLVLDLNETLLYTDWKRERGWRTFKRPGVDAFLEHLGKFYEIVVYSDQMEMYVLPVCEKLDPNGYIRYKLARGATKYENGKHYRDLSKLNRDPKKILFVSANAFESTLQPENSVPIKPYKLEADDTALVDLIPFLEYVARNSPADIRPVLASFERKDIAKEFIDRSIEYQKRKQGQLGQGRFWRR", "length": 376, "molWeight": 42640, "crc64": "160466DD597215AA", "md5": "FCA8791FE922E1E45EE7A4ABB915F496"}}
{"primaryAccession": "Q8VYI3", "text": "This is Enoyl-CoA hydratase 2, peroxisomal protein, from Mouse-ear cress, contains 309 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VYI3", "organism_name": "Mouse-ear cress", "protein_name": "Enoyl-CoA hydratase 2, peroxisomal", "length": 309, "firstPublicDate": "2011-03-08", "FUNCTION": "Bidirectional monofunctional enoyl-CoA hydratase 2 involved in the degradation of even cis-unsaturated fatty acids, Devoid of 3-hydroxyacyl-CoA dehydrogenase activity", "SUBCELLULAR LOCATION": "Peroxisome", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATSDSEFNSDLLLAHKLPETRYTYNERDVAIYALGIGACGQDAVDSDELKFVYHRNGQDLIQVLPTFASLFTLGSLTEGLDLPGFKYDPSLLLHGQQYIEIYRPLPSKASLINKVSLAGLQDKGKAAILELETRSYEEGSGELLCMNRTTVFLRGAGGFSNSSQPFSYKNYPSNQGLAVKIPQRQPLTVCEERTQPSQALLYRLSGDYNPLHSDPEFAKLAGFPRPILHGLCTLGFAIKAIIKCVCKGDPTAVKTISGRFLTTVFPGETLITEMWLEGLRVIYQTKVKERNKTVLAGYVDIRGLSSSL", "length": 309, "molWeight": 34082, "crc64": "FC98938543619B76", "md5": "7B8D3666F7BF367DE057470B27520807"}}
{"primaryAccession": "Q8VYN6", "text": "This is ATP-dependent 6-phosphofructokinase 5, chloroplastic protein, from Mouse-ear cress, contains 537 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VYN6", "organism_name": "Mouse-ear cress", "protein_name": "ATP-dependent 6-phosphofructokinase 5, chloroplastic", "length": 537, "firstPublicDate": "2008-04-29", "FUNCTION": "Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the phosphofructokinase type A (PFKA) family, PPi-dependent PFK group II subfamily, Atypical ATP-dependent clade 'X' sub-subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDALSQAISSGISVPYKNNSSSLVPSHGLTSLILRKSRSPVNPSSRSRVSVRASEIQHSKTSASSIDLSDPDWKLKYEKDFEQRFSIPHITDVLPDAEAIRSTFCLKMRSPTEDFVGGYPSDEEWHGYINNNDRVLLKVISYSSPTSAGAECLDHDCSWVEQWIHRAGPREKIYFRPEEVKAAIITCGGLCPGLNDVIRHIVITLEIYGVKNIVGIPFGYRGFSDKDLTEMPLSRKVVQNIHLSGGSLLGVSRGGPSVSEIVDSMEERGINMLFVLGGNGTHAGANAIHNECRKRKIKVAVVGVPKTIDNDILHMDKTFGFDTAVEEAQRAINSAYIEAHSAYHGIGVVKLMGRNSGFIAMQASLASGQVDICLIPEVPFNLHGPNGVLKHLKYLIETKGSAVICVAEGAGQNFLEKTNAKDASGNAVLGDFGVYIQQETKKYFKEISTPIDVKYIDPTYMIRAVRANASDGILCTVLGQNAVHGAFAGYSGITVGIINTHYAYLPITEVIAYPKSVDPNSRMWHRCLTSTGQPDFI", "length": 537, "molWeight": 58615, "crc64": "5A9DD3004D1ACC6A", "md5": "97A9A7A5E0FF58275AA2399B0C1E1E53"}}
{"primaryAccession": "Q8VZJ2", "text": "This is Probable glucan endo-1,3-beta-glucosidase At4g16260 protein, from Mouse-ear cress, contains 344 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VZJ2", "organism_name": "Mouse-ear cress", "protein_name": "Probable glucan endo-1,3-beta-glucosidase At4g16260", "length": 344, "firstPublicDate": "2015-11-11", "FUNCTION": "May be involved in plant defense against cyst nematode pathogens", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 17 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTTLFLLIALFITTILNPTSGESVGVCYGMMGNNLPSQSDTIALFRQNNIRRVRLYDPNQAALNALRNTGIEVIIGVPNTDLRSLTNPSSARSWLQNNVLNYYPAVSFKYIAVGNEVSPSNGGDVVLPAMRNVYDALRGANLQDRIKVSTAIDMTLIGNSFPPSSGEFRGDVRWYIDPVIGFLTSTNSALLANIYPYFSYVDNPRDISLSYALFTSPSVVVWDGSRGYQNLFDALLDVVYSAVERSGGGSLPVVVSESGWPSNGGNAASFDNARAFYTNLASRVRENRGTPKRPGRGVETYLFAMFDENQKSPEIEKNFGLFFPNKQPKFPITFSAARDGTAVE", "length": 344, "molWeight": 37712, "crc64": "B96F8FD95C9DC670", "md5": "E924A32E7F8702A55679C7DDB947826C"}}
{"primaryAccession": "Q8VZL6", "text": "This is SWR1-complex protein 4 protein, from Mouse-ear cress, contains 441 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8VZL6", "organism_name": "Mouse-ear cress", "protein_name": "SWR1-complex protein 4", "length": 441, "firstPublicDate": "2015-04-29", "FUNCTION": "Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling, Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SWC4 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGGTDAKDILGLPKTPLSLTQEKKSRPQKESHRKPDGISREVYALTGGVAPLMPSIDLKRRPPADEKVAWKWLSFTNSARKDDLQLYHWVRVVNDVPPTGDYSFAKYNKSVDILKYTDEEYENHLTDSVWTKEETDQLFEFCQNFDLRFVVIADRFPVSRTVEELKDRYYSVNRALLRARAQSPADVANHPLMKEPYDITRDRERKRALSMVLSQSRHQEKKDAEILAEAKRITEMRLAARRAEEPDVSANENAGLDKADGVVPGRSVSPTSNSQLPATAVAPSTLTMADYASTLASLRMLHVYLRTYGLEQMVQAASSAVGLRTIKRVEQTLQDLGVNLKPKVPTKTVCDEHLELRKEILTLLNLQKQLQYKESEGSSHREGSYAAMPDTPKDRVFAPDPFSFGAERPIKKEQKRKGPGRQADTPSPAHKRPRKLKASDL", "length": 441, "molWeight": 49824, "crc64": "6D98F3B4DED25A74", "md5": "80C619C4FD6B393330134C543AF7D7A7"}}
{"primaryAccession": "Q8WSR7", "text": "This is Countin-2 protein, from Social amoeba, contains 254 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WSR7", "organism_name": "Social amoeba", "protein_name": "Countin-2", "length": 254, "firstPublicDate": "2008-04-08", "FUNCTION": "Cell-counting factor that limits the minimum size of the multicellular structure, May up-regulate the expression of both gp24 and gp80, which mediate cell adhesion", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the countin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMIKYITIAILFIASLVKADLQFSLCPTCVDFINNDMGDLEKIISGGIATSCGAVCSLLPNNIEQGACNLLCDIVGIDEFLKVFNNIGEDADPVWICEELTVCPKNQNSNATVLTSDVSPASGPHGTTFTIGVAYKVESTLGTGEVAVMVTDPTGSNGFGDAQLIVNTQPGQYSTSFSFAATPSEDEQFPAGVYQVQLMICEGSCGAKHSVTFNSVYANFTVTSGPSVTGQMTGTGSGSGSGSGSSSGAAYLRY", "length": 254, "molWeight": 26347, "crc64": "359482BE25C6D3AF", "md5": "7FED17C6DDA5C989C7A21B9811BAD7A7"}}
{"primaryAccession": "Q8WTC1", "text": "This is Small ribosomal subunit protein uS15m protein, from Fruit fly, contains 280 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WTC1", "organism_name": "Fruit fly", "protein_name": "Small ribosomal subunit protein uS15m", "length": 280, "firstPublicDate": "2003-05-30", "FUNCTION": "Essential for gut mitochondrial activity, Might be involved in tissue specific growth factor production", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uS15 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNKLLNIAQAGHRQFVREYAFKSDLKIKWMRPEKIACYKPEKSGDLAKLPPLKADELLPEYRDCKELDKADESVKSLFKLSNNASYLTTKFYRDEMVKEVQRHAQDFGSMEAKLAKMTAVIRRYQEHMDKHPRDKMIKVRLKELIDKRKKFLKYLRRWDYPRFEWILEKLDLVYKPPPTHFHWITRKESLQKLTDIYCENLKEERLEAYHKQLQAQQIPFLEEAIKKMQFVRQEQISCDVPVTVTEEKIADSKRQLEMLKELQQAEAAASSKKQNEDGFN", "length": 280, "molWeight": 33473, "crc64": "4CB921573734A08B", "md5": "577B8C4A8C49F2C856097B073951211A"}}
{"primaryAccession": "Q8WZK2", "text": "This is GPI ethanolamine phosphate transferase 1 protein, from Fission yeast, contains 935 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WZK2", "organism_name": "Fission yeast", "protein_name": "GPI ethanolamine phosphate transferase 1", "length": 935, "firstPublicDate": "2004-03-29", "FUNCTION": "Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis, Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the PIGG/PIGN/PIGO family, PIGN subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFGRLLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAGEAPAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEPSSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYAFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHIRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDIGVSISHFCISNFLILFITALEHASAILCKNITYTIHEKVN", "length": 935, "molWeight": 106404, "crc64": "A92DADCF1D932CE2", "md5": "65591AE26A6B2427252DFB9C7F80FE4F"}}
{"primaryAccession": "Q8X168", "text": "This is Arabinogalactan endo-beta-1,4-galactanase A protein, from Aspergillus niger, contains 350 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8X168", "organism_name": "Aspergillus niger", "protein_name": "Arabinogalactan endo-beta-1,4-galactanase A", "length": 350, "firstPublicDate": "2010-06-15", "FUNCTION": "Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 53 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIYPLLLSALPLLSSAALTYRGADISSLLIEEDAGISYKNLNGETQALEDILVNNGVNSIRQRVWVDPSDGSYDLDYNLKLAKRVQAAGMSIYLDLHLSDTWADPSDQTTPTGWSTTDIDTLTWQLYNYTLDVCNTFAENDIDIEIVSIGNEISSGLLWPLGKTSNYDNIAKLLHSGAWGVKDSNQATTPKIMIHLDNGWDWEEQEYFYKTVLATGSLLSTDFDLMGVSYYPFYNSEATLSALQTSLTNMQSNYDKSVVVVETNWPVSCPDPEYSFPSDLSSIPFSAAGQEEFLEKLAEVVEGVTDGLGIYYWEPAWVDNAALGSSCADNLMVDIDTDEVLESVTVFEDL", "length": 350, "molWeight": 38734, "crc64": "3353286DECB85DD6", "md5": "6B6EA4EB9EA451CDB10087B19E0F7885"}}
{"primaryAccession": "Q90812", "text": "This is Corticotropin-releasing factor receptor 1 protein, from Chicken, contains 420 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q90812", "organism_name": "Chicken", "protein_name": "Corticotropin-releasing factor receptor 1", "length": 420, "firstPublicDate": "1997-11-01", "FUNCTION": "G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin), Has high affinity for CRH and UCN, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase, Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVPGPRPALLLLLFLLQAFLLWDSPVAASIQEQYCESLLPTTNHTGPQCNASVDLIGTCWPRSAVGQLVARPCPEYFYGVRYNTTNNGYRECLANGSWAARVNYSQCQEILSEEKRSKLHYHIAVIINYLGHCVSLGTLLVAFVLFMRLRSIRCLRNIIHWNLITAFILRNATWFVVQLTMNPEVHESNVVWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDKLRKWMFICIGWCIPFPIIVAWAIGKLYYDNEKCWFGKRAGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLSLLGITYMLFFVNPGEDEISRIVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSSAV", "length": 420, "molWeight": 48600, "crc64": "8C5C992925F62316", "md5": "AD444A8E0803DE83191A26D9F43547B5"}}
{"primaryAccession": "Q91826", "text": "This is PYLa/PGLa B protein, from African clawed frog, contains 64 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91826", "organism_name": "African clawed frog", "protein_name": "PYLa/PGLa B", "length": 64, "firstPublicDate": "2012-02-22", "FUNCTION": "PGLa and PGLa-H display a broad-spectrum of antibacterial activity against a range of Gram-positive and Gram-negative bacteria, PGLa also displays antifungal activity against C,albicans ATCC 14053, PGLa-H shows moderate antibacterial activity against the multidrug-resistant methicillin-resistant S,aureus (MRSA) but exhibits very little hemolytic activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the gastrin/cholecystokinin family, Magainin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MYKQIFLCLIIAALCATIMAEASALADADDDDDKRYVRGMASKAGAIAGKIAKVALKALGRRDS", "length": 64, "molWeight": 6761, "crc64": "6BA7A49205AD7BF0", "md5": "9E9C8557D6DFDECFBE880D1E5E9EFAF2"}}
{"primaryAccession": "Q920S2", "text": "This is Serine protease 41 protein, from Mouse, contains 322 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q920S2", "organism_name": "Mouse", "protein_name": "Serine protease 41", "length": 322, "firstPublicDate": "2008-07-22", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGIQGPVLLLLLLCVMLGKPGSREESQAADLKSTDIKLLSMPCGRRNDTRSRIVGGIESMQGRWPWQASLRLKKSHRCGGSLLSRRWVLTAAHCFRKYLDPEKWTVQLGQLTSKPSYWNRKAYSGRYRVKDIIVNSEDKLKSHDLALLRLASSVTYNKDIQPVCVQPSTFTSQHQPRCWVTGWGVLQEDLKPLPPPYHLREVQVSILNNSRCQELFEIFSLHHLITKDVFCAGAEDGSADTCSGDSGGPLVCNMDGLWYQIGIVSWGIGCGRPNLPGIYTNVSHYYNWIETMMILNGAVRRDLALPLLSITLLQAPWLLRPT", "length": 322, "molWeight": 36218, "crc64": "ED55F9A199A3E491", "md5": "947DAFF57A5A0EA91F38DFF02087BB83"}}
{"primaryAccession": "Q923Z3", "text": "This is Protein MTO1 homolog, mitochondrial protein, from Mouse, contains 669 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q923Z3", "organism_name": "Mouse", "protein_name": "Protein MTO1 homolog, mitochondrial", "length": 669, "firstPublicDate": "2005-10-25", "FUNCTION": "Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MnmG family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFLLRGRGHWAAASLGRRLPLRRLRSDSAAPCTPHFDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGIHYKVLNRRKGPAVWGLRAQIDRKLYKQNMQKEILSTPLLTVQKGAVEDLVLAEPEPGYPGKSRVRGVVLADGSTIYAESVILTTGTFLRGMIIIGLEMHPAGRLGDQPSIGLAQTLEKLGFMVGRLKTGTPPRLGKESINFSILNKHTPDDPSIPFSFLSDSVWIKPEDQLPCYLTHTNPRVDAIVLENLHLNSHVQETTKGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMVHPGYGVQYDYLDPRQISPSLETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLSLRPDNADTRLTFRAHKEAGCVSSQRFERALWMKSSLEEGISVLKSIKFSSSKWKKLIPQIPISINRSLPVSALDVLKYEEVDMESLVGVLPEPLEKYTACRELARRLKIEASYESVLSYQLQEIKEVQQDEALQLPHELDYLTIRDVSLSQEVREKLHLSRPQTIGAASRIPGVTPAAIINLLRFVRSTRQSRQQ", "length": 669, "molWeight": 74332, "crc64": "4DE2FFD8DE754FF7", "md5": "D859AE5205CC7F0A2D398DBA884B7015"}}
{"primaryAccession": "Q924M5", "text": "This is Protein boule-like protein, from Mouse, contains 293 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q924M5", "organism_name": "Mouse", "protein_name": "Protein boule-like", "length": 293, "firstPublicDate": "2004-03-01", "FUNCTION": "Probable RNA-binding protein, which may be required during spermatogenesis, May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the RRM DAZ family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "METESRAQSTNQTQTDSLSPSPNPVSPVPLNNPTSGPRYGTVIPNRIFVGGIDFKTNENDLRKFFSQYGSVKEVKIVNDRAGVSKGYGFITFETQEDAQKILQEAEKLNYKDKKLNIGPAIRKQQVGIPRSSLMPAAGTMYLTTSTGYPYTYHNGVAYFHTPEVTSVPPSWPSRSISSSPVMVAQPVYQQPAYHYQAPAQCLPGQWQWGVPQSPASSAPFLYLQPSEVIYQPVEIAQDGGCVPPPLSLMETSVPEPYSDHGVQAAYHQVYASSAIAMPAPMMQPEPIKVRSLF", "length": 293, "molWeight": 32189, "crc64": "84730F2C8D062DD7", "md5": "69E7D31047E970CAA189E40053BC2AC1"}}
{"primaryAccession": "Q93V61", "text": "This is Phospholipase A(1) LCAT3 protein, from Mouse-ear cress, contains 447 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q93V61", "organism_name": "Mouse-ear cress", "protein_name": "Phospholipase A(1) LCAT3", "length": 447, "firstPublicDate": "2010-10-05", "FUNCTION": "Hydrolyzes the sn-1 acylester bond of phospholipids, Phosphatidylcholine, phosphatidylethanolamine and phosphatidic acid can be used as substrates, Weak activity with lysophosphatidylcholine and no activity with tripalmitoylglycerol and cholesteryl oleate, Seems to have a preference for unsaturated fatty acids at the sn-1 position", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGWIPCPCWGTNDDENAGEVADRDPVLLVSGIGGSILHSKKKNSKSEIRVWVRIFLANLAFKQSLWSLYNPKTGYTEPLDDNIEVLVPDDDHGLYAIDILDPSWFVKLCHLTEVYHFHDMIEMLVGCGYKKGTTLFGYGYDFRQSNRIDLLILGLKKKLETAYKRSGGRKVTIISHSMGGLMVSCFMYLHPEAFSKYVNKWITIATPFQGAPGCINDSILTGVQFVEGLESFFFVSRWTMHQLLVECPSIYEMMANPDFKWKKQPEIRVWRKKSENDVDTSVELESFGLIESIDLFNDALKNNELSYGGNKIALPFNFAILDWAAKTREILNKAQLPDGVSFYNIYGVSLNTPFDVCYGTETSPIDDLSEICQTMPEYTYVDGDGTVPAESAAAAQFKAVASVGVSGSHRGLLRDERVFELIQQWLGVEPKKAKRKHLRTHKVVDSG", "length": 447, "molWeight": 50349, "crc64": "F24D3903BB60D22A", "md5": "4ECA8F98A98855217CEF7E8527E9CDF6"}}
{"primaryAccession": "Q948U0", "text": "This is Respiratory burst oxidase homolog protein A protein, from Potato, contains 963 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q948U0", "organism_name": "Potato", "protein_name": "Respiratory burst oxidase homolog protein A", "length": 963, "firstPublicDate": "2008-01-15", "FUNCTION": "Calcium-dependent NADPH oxidase that generates superoxide, Involved in the rapid and transient phase I oxidative burst induced by pathogen infection", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the RBOH (TC 5,B,1,3) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRGLPGHERRWTSDTVSSGKDLSGESSPGTDSGNISGFASEEFVEVILDLQDDDTIILRSVEPATVINIDASDPATGVGIGGVSIETPASLTSTSGTRSPTMRRSTSNKLRQFSQELKAEAVAKAKHFSQELKAELRRFSWSHGHASRTFSPASFFQNAVVGTGNGVDSALAARALRRQRAQLDRTRSSAHKALRGLKFISNNKTNGWNEVENNFAKLAKDGYLYRSDFAQCIGMKDSKEFALELFDALSRRRRLKVDKISKEELYEYWSQITDQSFDSRLQIFFDMVDKNEDGRIGEEEVKEIIMLSASANKLSRLKEQAEEYAALIMEELDPERLGYIELWQLETLLLQKDTYLNYSQALSYTSQALSQNLQGLRKRSPIRRMSTKLVYSLQENWKRIWVLVLWILIMIGLFLWKFYLYKQKSAFQVMGYCLLTAKGAAETLKFNMALILLPVCRNTITFLRSTKLSCFVPFDDNINFHKTVAAAIVTGIILHAGNHLVCDFPKLIHANNTNYQKYLVNDFGPSQPQYIDLVKGVEGVTGIIMVILMAIAFTLATRWFRRSLIKFPKPFDRLTGFNAFWYSHHLLIIVYIVLIIHGTFLYLVHNWYSKTTWMYLAVPVLLYAGERTLRFFRSGLYTVRLLKVAIYPGNVLTLQMSKPPQFRYKSGQYMFVQCPAVSPFEWHPFSITSAPGDDYLSIHIRQLGDWTQELKRVFSEACEQPEAGKSGLLRADENTKTSLPKLLIDGPYGAPAQDYRKYDVLLLVGLGIGATPFISILKDLLKNIVTMEEQADLVSDFSGNSDMSAATSEQPALNKISPKKRKSTLKTTNAYFYWVTREQGSFDWFKGVMNEVAELDQRGVIEMHNYLTSVYEEGDARSALITMVQALNHAKNGVDIVSGTSVRTHFARPNWRKVFSKTLTKHANARIGVFYCGAPILAKELSKLCKEFNQKGTTKFEFHKEHF", "length": 963, "molWeight": 109146, "crc64": "501BB92E1157A4F9", "md5": "D04A9AED70F9C93CBC2714650A1F9A77"}}
{"primaryAccession": "Q949W6", "text": "This is Protein KAKU4 protein, from Mouse-ear cress, contains 485 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q949W6", "organism_name": "Mouse-ear cress", "protein_name": "Protein KAKU4", "length": 485, "firstPublicDate": "2015-04-29", "FUNCTION": "Required for nucleus structure organization (e,g, size and shape)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDSVSGYAAGAGQPRVGGKIVRPRRTAVVRTPCERPVQRSRDPPQQNPSWISRLVYKPASVIASGAGKFISSVVFSDSSSSSEEDEDSSSDIDGDEDVEKNNPDFTEEDLLSAQQPSIQRLSSKRVIEQLLLQETFAREEGDRLIDIIKARVVDHPSVPSAIETSHDDYGLTSDVNVGEMSNTAVMEARKWLEEKKSGSSSKYKATEDGAGSPVDVAKSYMRARLPWGSPAANNLDFRSPSSARVQGTPLPYSAGNFSSSKLKRKSGSNQSWNIQDEIRKVRAKATEEMLKSPSSVASLEPKYSPYVLATDMLKGNASSLNADGAVRNEQSRALPNSAIPTSEHNQTTEANQAVKETGVLHTRSRGVGLEETFISTQGVKPSEDTNTAPQSGTAVDDFNDQDGDFIQPTSTIGNTTNAVLALGATLDPTGNSCIPKDVFETSKEADEIGASRHTSNGFPSSSPSGYGRSTKTHTTRRNQGFSAYS", "length": 485, "molWeight": 52148, "crc64": "A7FD825621BD35E5", "md5": "0FB89B5332323792402CFB9E79AAC9CB"}}
{"primaryAccession": "Q94AV5", "text": "This is WPP domain-interacting protein 3 protein, from Mouse-ear cress, contains 459 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94AV5", "organism_name": "Mouse-ear cress", "protein_name": "WPP domain-interacting protein 3", "length": 459, "firstPublicDate": "2008-09-02", "FUNCTION": "Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips (PubMed:17600715), As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNESVPDSVEDNGNSVPANGLLVLPDNDHEEGGVGSPQRSNSVESPGGSVHSTRKGFGLKKWRRIKRDGPVRDEAAPVDDGSKLLKRGLAGLVNPPSKHVEFSSVEARQSSEGSVGSVNMVHHPGVANGFSPDIGCMFAVGQAFEKSEEHSGNTIGGKNVVGGKVVSGSQEKLWSDTIKRASEERGDIEKEKPCSSLDSDLRSSDFVFSTGSVSVGNHGEKDERLTMNYIGGFSNEGQVKEEVQTYSRSENGNKEDDGESKKNNNHWADKDALADSIRSFAVLQEVLWKEVQSFQELGKESVLLHSNTDELSSDQPSHQNCKEDNSTSSGSKALILKEKVKLLEHKLEEARAALEAKEARIQELENSKIESELECIFQRKIETEIEHLMLTRSLSSLQVLQETKKLHSLKEDPVSNRGNILGKTCKLGFYILTQLILLVSILRFLVLQFSPASRLVIPT", "length": 459, "molWeight": 50274, "crc64": "6FAD2C63953AAC07", "md5": "537F69364CA5841CCD89FF52DA94374B"}}
{"primaryAccession": "Q94F00", "text": "This is Phosphatase IMPL1, chloroplastic protein, from Mouse-ear cress, contains 371 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94F00", "organism_name": "Mouse-ear cress", "protein_name": "Phosphatase IMPL1, chloroplastic", "length": 371, "firstPublicDate": "2009-09-22", "FUNCTION": "Phosphatase acting preferentially on D-myoinositol 1-phosphate (D-Ins 1-P)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the inositol monophosphatase superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGRSLIFSGNMSLRISHLPRSSLPLQNPISGRTVNRTFRYRCTRILSNSFKSTTRLQTKAVLSEVSDQTRYPRIGAKTTGTISPAHLLEVVELAAKTGAEVVMEAVNKPRNITYKGLSDLVTDTDKASEAAILEVVKKNFSDHLILGEEGGIIGDSSSDYLWCIDPLDGTTNFAHGYPSFAVSVGVLYRGNPAAASVVEFVGGPMCWNTRTFSATAGGGALCNGQKIHVSKTDAVERALLITGFGYEHDDAWSTNMELFKEFTDVSRGVRRLGAAAVDMCHVALGIAESYWEYRLKPWDMAAGVLIVEEAGGAVTRMDGGKFSVFDRSVLVSNGVLHPKLLERIAPATENLKSKGIDFSLWFKPEDYHTEL", "length": 371, "molWeight": 40445, "crc64": "52B3690BE791F089", "md5": "E84CC58849B684D208EAFDAA414F6A92"}}
{"primaryAccession": "Q94JX5", "text": "This is LIM domain-containing protein WLIM1 protein, from Mouse-ear cress, contains 190 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94JX5", "organism_name": "Mouse-ear cress", "protein_name": "LIM domain-containing protein WLIM1", "length": 190, "firstPublicDate": "2014-10-29", "FUNCTION": "Binds to actin filaments and promotes cross-linking into thick bundles, Has an actin-stabilizing activity, The actin regulatory activities are not regulated by pH and [Ca(2+)]", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFAGTTQKCMACDKTVYLVDKLTADNRVYHKACFRCHHCKGTLKLSNYNSFEGVLYCRPHFDQNFKRTGSLEKSFEGTPKIGKPDRPLEGERPAGTKVSNMFGGTREKCVGCDKTVYPIEKVSVNGTLYHKSCFKCTHGGCTISPSNYIAHEGKLYCKHHHIQLIKEKGNLSQLEGGGENAAKDKVVAA", "length": 190, "molWeight": 21040, "crc64": "6D8DE2172BAC17E7", "md5": "CA5130D6553334024B0FFB36BCED22EC"}}
{"primaryAccession": "Q95T19", "text": "This is Serine--tRNA synthetase-like protein Slimp protein, from Fruit fly, contains 464 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q95T19", "organism_name": "Fruit fly", "protein_name": "Serine--tRNA synthetase-like protein Slimp", "length": 464, "firstPublicDate": "2016-05-11", "FUNCTION": "Essential protein which may play a role in mitochondrial morphogenesis and function, Has transfer RNA (tRNA)-binding activity and can bind tRNA(Ser) but does not have serine--tRNA ligase activity and does not bind ATP", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the class-II aminoacyl-tRNA synthetase family, Type-1 seryl-tRNA synthetase subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLSLRSVLKHCLSAKKTCSRNISALYITGDKANENYVTLQPYMDFNKTFGERQFLEQSISSRGLDIRLETVLSKYEKYKTHHAQLSKVAEERERVTKRLKELTKSGSSAVQLEELKEHGKSLRNELKALKQTLYPIEDDFIHDYLHLPNLLHVQCPVGGEEKLLYRHGIPKSENKTTSHLARQELVHFVDNNRYYLMEQAALFDVNAMQSLARYFVNHGHFIQTANPDFVRCVLLEANATPLSDYHLVQEEHLQNKINTAYLTGGASFESYLGAMTKLCVYPSVLPLRYVCCGRSYNRAEADLYGPIPSLYTATQTNAVQIFVATQTDNEADSQLEHILNLATDFYKALDIPFRISYATAADLTPAESIRAVIEVYAPSLQRYVCVGRISNYGDFVSKRILFSTRREKHYDFLHMVGGPVLYTSRLIAALVEHGVRLEDCKLLGSISQKPVHQQDLQQFKDLFT", "length": 464, "molWeight": 52916, "crc64": "BA25758EED8CB40F", "md5": "D2DF0F7F2BA97BFB63E153961EFDA01B"}}
{"primaryAccession": "Q96BH3", "text": "This is Epididymal sperm-binding protein 1 protein, from Human, contains 223 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96BH3", "organism_name": "Human", "protein_name": "Epididymal sperm-binding protein 1", "length": 223, "firstPublicDate": "2007-10-23", "FUNCTION": "Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation, Has phosphorylcholine-binding activity (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the seminal plasma protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTRWSSYLLGWTTFLLYSYESSGGMHEECVFPFTYKGSVYFTCTHIHSLSPWCATRAVYNGQWKYCQSEDYPRCIFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCETNEYGGNSLRKPCIFPSIYRNNVVSDCMEDESNKLWCPTTENMDKDGKWSFCADTRISALVPGFPCHFPFNYKNKNYFNCTNEGSKENLVWCATSYNYDQDHTWVYC", "length": 223, "molWeight": 26106, "crc64": "FC7C215BA3E5CE51", "md5": "A03899F0ADCDF8BB9521E7D122E60A36"}}
{"primaryAccession": "Q98SJ2", "text": "This is DAZ-associated protein 1 protein, from African clawed frog, contains 360 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q98SJ2", "organism_name": "African clawed frog", "protein_name": "DAZ-associated protein 1", "length": 360, "firstPublicDate": "2004-03-01", "FUNCTION": "RNA-binding protein, which is required during gametogenesis, May be involved in the actin-dependent anchoring of Vg1 mRNA in the vegetal cortex of the oocyte", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNNQGGDEIGKLFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLASRPHTLDGRNIDPKPCTPRGMQPERSRPREGWQQKEPRTENSRSNKIFVGGIPHNCGETELKEYFNRFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVNMHFHDIMGKKVEVKRAEPRDSKSQTPGPPGSNQWGSRAMQSTANGWTGQPPQTWQGYSPQGMWMPTGQTIGGYGQPAGRGGPPPPPSFAPFLVSTTPGPFPPPQGFPPGYATPPPFGYGYGPPPPPPDQFVSSGVPPPPGTPGAAPLAFPPPPGQSAQDLSKPPSGQQDFPFSQFGNACFVKLSEWI", "length": 360, "molWeight": 39229, "crc64": "E12F31961CBADAF6", "md5": "7DCA4BF6B07C57966D2B3D653A0DA22A"}}
{"primaryAccession": "Q99134", "text": "This is PYLa/PGLa A protein, from African clawed frog, contains 64 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99134", "organism_name": "African clawed frog", "protein_name": "PYLa/PGLa A", "length": 64, "firstPublicDate": "1995-02-01", "FUNCTION": "PGLa and PGLa-H display a broad-spectrum of antibacterial activity against a range of Gram-positive and Gram-negative bacteria, PGLa also displays antifungal activity against C,albicans ATCC 14053, PGLa-H shows moderate antibacterial activity against the multidrug-resistant methicillin-resistant S,aureus (MRSA) but exhibits very little hemolytic activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the gastrin/cholecystokinin family, Magainin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MYKQIFLCLIIAALCATIMAEASAFADADEDDDKRYVRGMASKAGAIAGKIAKVALKALGRRDS", "length": 64, "molWeight": 6809, "crc64": "630527391F1D7BFE", "md5": "82AB13A64057BBC7DE584F178B0BE730"}}
{"primaryAccession": "Q99332", "text": "This is Protein HPH1 protein, from Baker's yeast, contains 602 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99332", "organism_name": "Baker's yeast", "protein_name": "Protein HPH1", "length": 602, "firstPublicDate": "2006-03-21", "FUNCTION": "Calcineurin-dependent protein required for growth under high NaCl, alkaline pH and cell wall stress", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNLLIDRMENPGSRNCTLLPPSFPRGFCKGRRASSGDAVKIKESGLQPQPQPEPLQAKTNVAHFSKSSSRLPVIAVNDNPVVPRPSTEVNLGSLLQKEREKEKEEQPALHDRRHLYVTKNRAHGVRQRSLEMTSLPVLGSTKTGKFSDFLFEDDIDNRVGRHSRSYSGASSLDDPFRVSPKTDFNSNRARLSCLSKGRRGSMSVFQSCHTGLAFNQIQGSSSSQRRSSAGSFDYERKRLVNQFLQPSLGNSDPFDTLRESVVFEPSSTAGGIKLGNMHSQSQISVNSSPSTSLFYHDLDGSAVNDSSSFLYSRSNVPAFLSSSAFSSTSSTSSDSEDVDRRSLNGVYPSLGYLTNQRKPRNSSGSSTAPGTDTLGFKYLLNRQKSADSSTRFKSVLKVNNNNGSAATPDSSSNSISKSNSNLNDNIDELNYYQNHISTLLVKIENEMRRNLNDTIIKNENNVQKTIQKYDLLSGELTLLLDEMTTLRTTVINQFLVKLKSDFDEDDNKAFINELKISVEESVAQLQGLERRMEVCQERLNKQKSSLREMDSLIELKNVLNKSKNNTKSIYLYRYFIIDIIAFLLMGGFIVYVKNLLTRFFTR", "length": 602, "molWeight": 67293, "crc64": "1F39BCD1DAD25AC4", "md5": "29B8E1E569F2BB9FA51028E185E2FEC4"}}
{"primaryAccession": "Q99678", "text": "This is G-protein coupled receptor 20 protein, from Human, contains 358 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99678", "organism_name": "Human", "protein_name": "G-protein coupled receptor 20", "length": 358, "firstPublicDate": "1997-11-01", "FUNCTION": "Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPSVSPAGPSAGAVPNATAVTTVRTNASGLEVPLFHLFARLDEELHGTFPGLWLALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGARGCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAGAVTLSVLGVTGSRPCCRVFALTVLEFLLPLLVISVFTGRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVRGLFGQHGEREPSSGDVVSMHRSSKGSGRHHILSAGPHALTQALANGPEA", "length": 358, "molWeight": 38650, "crc64": "5A34126C51BA732C", "md5": "5A268FE061CA832AB72363EBB619FDD1"}}
{"primaryAccession": "Q9ASQ7", "text": "This is S-type anion channel SLAH2 protein, from Mouse-ear cress, contains 519 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ASQ7", "organism_name": "Mouse-ear cress", "protein_name": "S-type anion channel SLAH2", "length": 519, "firstPublicDate": "2011-02-08", "FUNCTION": "Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the SLAC1 S-type anion channel family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNNPRSVSPLVSPANHSDLLENQRQSGSGDFSRLEKRIGARKMKFHSKSMPRGAMFLDQEASRNFHDKRYDLFRTMSGKLERQISNLRGKPTESSLQDHKEITESLTADRYFDALQGPELETLKEKEKIVLPEDKTWPFLLRFPITSYGMCLGVSSQAIMWKTLATTEAEKFLHVTQVINHVLWWISLLLLLAVSITYLFKTILFFEAVRREFRHPIRVNFFFAPLISILFLALGIPHSIISHLPSTLWYFLMAPILFLEMKIYGQWMSGGQRRLSKVANPTNHLSIVGNFAGALLGASMGLKEGPIFFFAIGLAYYLVLFVTLYQRLPTNETLPKELHPVFFLFVAAPAVASMAWTKISASFDLGSRLAYFISLFLYFSLVCRINLFRGFKFSLAWWAYTFPMTAVASATIKYSDEVTGVATKILSVVMSGAATLTVIAVLGLTVMHAFVQRDLFPNDVVIAISAEQPKQKRWFKHLTKESYGNNERCPKILDPEDNQIDLESPPLVNVDSSTVQNSN", "length": 519, "molWeight": 58820, "crc64": "C178C4889CF60A7A", "md5": "3BD754334E9F2384BAB3073A40740700"}}
{"primaryAccession": "Q9BSH3", "text": "This is Nicolin-1 protein, from Human, contains 213 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BSH3", "organism_name": "Human", "protein_name": "Nicolin-1", "length": 213, "firstPublicDate": "2004-08-31", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRVLVPCHVKGSVALQVGDVRTSQGRPGVLVIDVTFPSVAPFELQEITFKNYYTAFLSIRVRQYTSAHTPAKWVTCLRDYCLMPDPHSEEGAQEYVSLFKHQMLCDMARISELRLILRQPSPLWLSFTVEELQIYQQGPKSPSVTFPKWLSHPVPCEQPALLREGLPDPSRVSSEVQQMWALTEMIRASHTSARIGRFDVDGCYDLNLLSYT", "length": 213, "molWeight": 24202, "crc64": "2170A24989952652", "md5": "697E0E2880F2A35D3BCCADE2453D6C3D"}}
{"primaryAccession": "Q9BXL5", "text": "This is Hemogen protein, from Human, contains 484 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BXL5", "organism_name": "Human", "protein_name": "Hemogen", "length": 484, "firstPublicDate": "2006-07-11", "FUNCTION": "Regulates the proliferation and differentiation of hematopoietic cells, Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model, May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDLGKDQSHLKHHQTPDPHQEENHSPEVIGTWSLRNRELLRKRKAEVHEKETSQWLFGEQKKRKQQRTGKGNRRGRKRQQNTELKVEPQPQIEKEIVEKALAPIEKKTEPPGSITKVFPSVASPQKVVPEEHFSEICQESNIYQENFSEYQEIAVQNHSSETCQHVSEPEDLSPKMYQEISVLQDNSSKICQDMKEPEDNSPNTCQVISVIQDHPFKMYQDMAKREDLAPKMCQEAAVPKILPCPTSEDTADLAGCSLQAYPKPDVPKGYILDTDQNPAEPEEYNETDQGIAETEGLFPKIQEIAEPKDLSTKTHQESAEPKYLPHKTCNEIIVPKAPSHKTIQETPHSEDYSIEINQETPGSEKYSPETYQEIPGLEEYSPEIYQETSQLEEYSPEIYQETPGPEDLSTETYKNKDVPKECFPEPHQETGGPQGQDPKAHQEDAKDAYTFPQEMKEKPKEEPGIPAILNESHPENDVYSYVLF", "length": 484, "molWeight": 55341, "crc64": "E1464D1C7BEA1F07", "md5": "482628ED587F19EF7F39A5A63C59D3DE"}}
{"primaryAccession": "Q9BYC9", "text": "This is Large ribosomal subunit protein bL20m protein, from Human, contains 149 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BYC9", "organism_name": "Human", "protein_name": "Large ribosomal subunit protein bL20m", "length": 149, "firstPublicDate": "2006-09-05", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL20 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVFLTAQLWLRNRVTDRYFRIQEVLKHARHFRGRKNRCYRLAVRTVIRAFVKCTKARYLKKKNMRTLWINRITAASQEHGLKYPALIGNLVKCQVELNRKVLADLAIYEPKTFKSLAALASRRRHEGFAAALGDGKEPEGIFSRVVQYH", "length": 149, "molWeight": 17443, "crc64": "53AD05B3BBD9AE6B", "md5": "492A0AF62732117F8CE8A4BF1B0B882A"}}
{"primaryAccession": "Q9BYD1", "text": "This is Large ribosomal subunit protein uL13m protein, from Human, contains 178 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9BYD1", "organism_name": "Human", "protein_name": "Large ribosomal subunit protein uL13m", "length": 178, "firstPublicDate": "2002-08-13", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSFSRAPQQWATFARIWYLLDGKMQPPGKLAAMASIRLQGLHKPVYHALSDCGDHVVIMNTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHLRDPVAIVKLAIYGMLPKNLHRRTMMERLHLFPDEYIPEDILKNLVEELPQPRKIPKRLDEYTQEEIDAFPRLWTPPEDYRL", "length": 178, "molWeight": 20692, "crc64": "AF4FD524CC234D52", "md5": "BB12F039133781E6357BE2888814DADB"}}
{"primaryAccession": "Q9C5Y2", "text": "This is Ent-kaurenoic acid oxidase 2 protein, from Mouse-ear cress, contains 489 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C5Y2", "organism_name": "Mouse-ear cress", "protein_name": "Ent-kaurenoic acid oxidase 2", "length": 489, "firstPublicDate": "2004-07-19", "FUNCTION": "Catalyzes three successive oxidations of ent-kaurenoic acid giving gibberellin 12 (GA12), a key step in gibberellins (GAs) biosynthesis, GAs, which are involved many processes, including stem elongation, play a central role in plant development", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the cytochrome P450 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTETGLILMWFPLIILGLFVLKWVLKRVNVWIYVSKLGEKKHYLPPGDLGWPVIGNMWSFLRAFKTSDPESFIQSYITRYGRTGIYKAHMFGYPCVLVTTPETCRRVLTDDDAFHIGWPKSTMKLIGRKSFVGISFEEHKRLRRLTSAPVNGPEALSVYIQFIEETVNTDLEKWSKMGEIEFLSHLRKLTFKVIMYIFLSSESEHVMDSLEREYTNLNYGVRAMGINLPGFAYHRALKARKKLVAAFQSIVTNRRNQRKQNISSNRKDMLDNLIDVKDENGRVLDDEEIIDLLLMYLNAGHESSGHLTMWATILMQEHPMILQKAKEEQERIVKKRAPGQKLTLKETREMVYLSQVIDETLRVITFSLTAFREAKSDVQMDGYIIPKGWKVLTWFRNVHLDPEIYPDPKKFDPSRWEGYTPKAGTFLPFGLGSHLCPGNDLAKLEISIFLHHFLLKYRVERSNPGCPVMFLPHNRPKDNCLARITRTMP", "length": 489, "molWeight": 56750, "crc64": "945F204F6CB251DA", "md5": "539057875FD851D3508A6B9B9CBBC8C0"}}
{"primaryAccession": "Q9C8L2", "text": "This is Fatty-acid-binding protein 3, chloroplastic protein, from Mouse-ear cress, contains 287 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C8L2", "organism_name": "Mouse-ear cress", "protein_name": "Fatty-acid-binding protein 3, chloroplastic", "length": 287, "firstPublicDate": "2013-05-01", "FUNCTION": "Fatty-acid-binding protein, Interacts with most fatty acids tested and has maximal relative affinity for C16:0", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the chalcone isomerase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDGILAAVPSAVCVSLRISCRNLDNAESIYHFPGKSLNRVSVLQTGNYVSRKGNSLLKNRHCGEISRVIVKSAASSVGNAEDYAEETATSVKFKRSVTLPGCSSPLSLLGTGFREKKFAIIGVKVYAAGYYVNESILSGLSAWTGRSADEIQRDSSLFVSIFQAQAEKSLQIVLVRDVDGKTFWDALDEAISPRIKSPSSEDTTALSTFRGIFQNRPLNKGSVILLTWINTSNMLVSVSSGGLPTNVDATIESGNVTSALFDVFFGDSPVSPTLKSSVANQLAMTLV", "length": 287, "molWeight": 30729, "crc64": "BDBEB4F4F4E7D9F1", "md5": "9DF320E434B803EE83E838D6656BA249"}}
{"primaryAccession": "Q9C932", "text": "This is NAC domain-containing protein 19 protein, from Mouse-ear cress, contains 317 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C932", "organism_name": "Mouse-ear cress", "protein_name": "NAC domain-containing protein 19", "length": 317, "firstPublicDate": "2004-07-19", "FUNCTION": "Transcription factors that bind specifically to the 5'-CATGTG-3' motif", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGIQETDPLTQLSLPPGFRFYPTDEELMVQYLCRKAAGYDFSLQLIAEIDLYKFDPWVLPNKALFGEKEWYFFSPRDRKYPNGSRPNRVAGSGYWKATGTDKIISTEGQRVGIKKALVFYIGKAPKGTKTNWIMHEYRLIEPSRRNGSTKLDDWVLCRIYKKQSSAQKQVYDNGIANAREFSNNGTSSTTSSSSHFEDVLDSFHQEIDNRNFQFSNPNRISSLRPDLTEQKTGFHGLADTSNFDWASFAGNVEHNNSVPELGMSHVVPNLEYNCGYLKTEEEVESSHGFNNSGELAQKGYGVDSFGYSGQVGGFGFM", "length": 317, "molWeight": 35815, "crc64": "167EE787F05E3B45", "md5": "1DC58A46F5A4717CFB870A41CAD5EF67"}}
{"primaryAccession": "Q9C952", "text": "This is Cleavage and polyadenylation specificity factor subunit 3-I protein, from Mouse-ear cress, contains 693 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C952", "organism_name": "Mouse-ear cress", "protein_name": "Cleavage and polyadenylation specificity factor subunit 3-I", "length": 693, "firstPublicDate": "2010-03-02", "FUNCTION": "Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition, May function as mRNA 3'-end-processing endonuclease and also be involved in the histone 3'-end pre-mRNA processing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, INTS11 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASSSTSLKRREQPISRDGDQLIVTPLGAGSEVGRSCVYMSFRGKNILFDCGIHPAYSGMAALPYFDEIDPSSIDVLLITHFHIDHAASLPYFLEKTTFNGRVFMTHATKAIYKLLLTDYVKVSKVSVEDMLFDEQDINKSMDKIEVIDFHQTVEVNGIKFWCYTAGHVLGAAMFMVDIAGVRILYTGDYSREEDRHLRAAELPQFSPDICIIESTSGVQLHQSRHIREKRFTDVIHSTVAQGGRVLIPAFALGRAQELLLILDEYWANHPDLHNIPIYYASPLAKKCMAVYQTYILSMNDRIRNQFANSNPFVFKHISPLNSIDDFNDVGPSVVMATPGGLQSGLSRQLFDSWCSDKKNACIIPGYMVEGTLAKTIINEPKEVTLMNGLTAPLNMQVHYISFSAHADYAQTSTFLKELMPPNIILVHGEANEMMRLKQKLLTEFPDGNTKIMTPKNCESVEMYFNSEKLAKTIGRLAEKTPDVGDTVSGILVKKGFTYQIMAPDELHVFSQLSTATVTQRITIPFVGAFGVIKHRLEKIFESVEFSTDEESGLPALKVHERVTVKQESEKHISLQWSSDPISDMVSDSIVALILNISREVPKIVMEEEDAVKSEEENGKKVEKVIYALLVSLFGDVKLGENGKLVIRVDGNVAQLDKESGEVESEHSGLKERVRVAFERIQSAVKPIPLSAS", "length": 693, "molWeight": 77365, "crc64": "D225E47A675ACB1C", "md5": "850B2301EB4F3A10DEDC294446076217"}}
{"primaryAccession": "Q9C9N6", "text": "This is Protein PLASTID MOVEMENT IMPAIRED 2 protein, from Mouse-ear cress, contains 607 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C9N6", "organism_name": "Mouse-ear cress", "protein_name": "Protein PLASTID MOVEMENT IMPAIRED 2", "length": 607, "firstPublicDate": "2007-04-03", "FUNCTION": "Required for the chloroplast avoidance response under high intensity blue light, This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells, Acts in association with WEB1 to maintain the velocity of chloroplast photorelocation movement via cp-actin filaments regulation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the WEB family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGERNLDGTVSVKATINKYGQKATRSVIKSSVAEDLHKSGRELGIYRESRRVAESAKAKAEVELCKAKKIVKELTLRIEESNRRLKSRRIDIEAVMNESRIDGNGGYVRIMRELEDMKQELSKLKLDVVYVSREKVVAEKEVMELESRMEENLKLLESLKLEVDVANEEHVLVEVAKIEALKECKEVEEQREKERKEVSESLHKRKKRIREMIREIERSKNFENELAETLLDIEMLETQLKLVKEMERKVQRNESMSRSKNRAFERGKDNLSVLKEVTEATEAKKAELASINAELFCLVNTMDTLRKEFDHAKKETAWLDKMIQKDDVMLERLNTKLLIAKDQLEAVSKAEERISYLADNLTTSFEKLKSDREAAKKEELKLREEARIINNEIQKTETGFDGKEKELLSKLDELEKAKHAESLALEKLETMVEKTMETREMESRRNSTITISRFEYEYLSGKACHAEETAEKKVEAAMAWVEALKASTKAIMIKTESLKRVSGKTMLEEERESFRMQRSLSIKRLVQDEIQKFKGNSEDNGLINSPKPVRKSVRLSGKFAPVQGGKSRRYSSGNRATPTFFVIKKKKKVPNMVKFFSRKRRNSSLEQ", "length": 607, "molWeight": 70240, "crc64": "3BCC9D4188A87158", "md5": "06C3D7CFB44C0E1490E9DFED11D1F8C8"}}
{"primaryAccession": "Q9CXD9", "text": "This is Leucine-rich repeat-containing protein 17 protein, from Mouse, contains 443 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CXD9", "organism_name": "Mouse", "protein_name": "Leucine-rich repeat-containing protein 17", "length": 443, "firstPublicDate": "2004-08-31", "FUNCTION": "Involved in bone homeostasis, Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRIVAILLLFCLCRAAEPRKSSPGVLRSQGNPSRSHGRGGRRGSSPVKRYAPGLPCDVYTYLHEKYLDCQERKLVYVLPDWPQDLLHMLLARNKIRVLKNNMFAKFKRLKSLDLQQNEISKIESEAFFGLNKLTTLLLQHNQIKVLTEEAFIYTPLLSYLRLYDNPWHCTCELETLISMLQIPRNRNLGNYAKCGSPPALRNKKLLQLKPQELCDEEEKEQLDPKPQVSGIPAVIRPEADSTLCHNYVFPIQTLDCKRKELKKVPSNIPPDIVKLDLSSNKIRQLRPKEFEDVHELKKLNLSSNGIEFIDPAAFLGLIHLEELDLSNNSLQNFDYGVLEDLYFLKLLWLRDNPWRCDYSIHYLYYWLKHHYNVHYNGLECKTPEEYKGWSVGKYVRSYYEECPKDKLPAYPETFDQDTEDDEWQKIHRDHPAKKHRVRITIVG", "length": 443, "molWeight": 51852, "crc64": "CF5C962262BB555E", "md5": "8FB4E5C789288A87341B128F3A61754E"}}
{"primaryAccession": "Q9CY02", "text": "This is Alpha-hemoglobin-stabilizing protein protein, from Mouse, contains 102 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CY02", "organism_name": "Mouse", "protein_name": "Alpha-hemoglobin-stabilizing protein", "length": 102, "firstPublicDate": "2002-10-10", "FUNCTION": "Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development, Specifically protects free alpha-hemoglobin from precipitation", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the AHSP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAPFQSNKDLISTGIKEFNVLLDQQVFDDPLISEEDMVIVVHDWVNLYTNYYKKLVHGEQEEQDRAMTEFQQELSTLGSQFLAKYRTFLKSKEPPSNTLPSS", "length": 102, "molWeight": 11832, "crc64": "095A66942A06C7BA", "md5": "AF3CF2AF9BC7EE8E8151C8136264B0E7"}}
{"primaryAccession": "Q9D023", "text": "This is Mitochondrial pyruvate carrier 2 protein, from Mouse, contains 127 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9D023", "organism_name": "Mouse", "protein_name": "Mitochondrial pyruvate carrier 2", "length": 127, "firstPublicDate": "2002-09-19", "FUNCTION": "Mediates the uptake of pyruvate into mitochondria", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2,A,105) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAAGARGLRATYHRLMDKVELLLPKKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSTVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGSAGASQLFRIWRYNQELKSKGIQ", "length": 127, "molWeight": 14286, "crc64": "BE8AEC9DF74405A6", "md5": "1FB3FEE639DDCFC510CB128A0603FFEB"}}
{"primaryAccession": "Q9D1F4", "text": "This is Proline-rich AKT1 substrate 1 protein, from Mouse, contains 257 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9D1F4", "organism_name": "Mouse", "protein_name": "Proline-rich AKT1 substrate 1", "length": 257, "firstPublicDate": "2006-10-17", "FUNCTION": "Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals, mTORC1 is activated in response to growth factors or amino acids, Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1, Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases, Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis, mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E), mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation, Within mTORC1, AKT1S1 negatively regulates mTOR activity in a manner that is dependent on its phosphorylation state and binding to 14-3-3, Inhibits RHEB-GTP-dependent mTORC1 activation, Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms, May also play a role in nerve growth factor-mediated neuroprotection", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASGRPEELWEAVVGAAERFQARTGTELVLLTAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIAQAHRAATATRPPGPPPAPQPPSPAPSPPPRPALAREDEEEDEDEPTETETSGERLGGSDNGGLFMMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPTACPQPPATALPTQQYAKSLPVSVPVWAFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPRLNTSDFQKLKRKY", "length": 257, "molWeight": 27483, "crc64": "4BFFC8630DBBA5EC", "md5": "6821F4E965C80FD4F69551596D67AA52"}}
{"primaryAccession": "Q9D495", "text": "This is Synaptonemal complex central element protein 1 protein, from Mouse, contains 329 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9D495", "organism_name": "Mouse", "protein_name": "Synaptonemal complex central element protein 1", "length": 329, "firstPublicDate": "2006-11-28", "FUNCTION": "Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:15944401), Requires SYCP1 in order to be incorporated into the central element (PubMed:15944401, PubMed:16968740), May have a role in the synaptonemal complex assembly, stabilization and recombination (PubMed:15944401)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SYCE family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATRPQPLGMEPEGSADLLHGPEGARGQYGSTQKIEDLMDMVKKLQKVGSLEPRIEVLINRINEVQQAKKKASEELGEAQTVWDNLQKELDLLREEKVRLKDILNRKEETLRIMQLHCQEKESEAQRKHSMLQECKERISFLNSQIDKEKAKLRKLRLDFEEHLETLMSQHKDTLEFHKPEHLTKEMCVLDSSKEQLLKEEKLMKVKLEDVRQRLCALGGPEGSSSLIEGLFLRSHEAAAAMQMFKDENKKAEEFLEAAAQQHEQLQQRCHQLQQKRQRLKEELEKHGVQILAHSTQNEEDSSWRMASPKPVEVHEETAQDQERPSSRT", "length": 329, "molWeight": 38205, "crc64": "E843B245EDE1C029", "md5": "7A0AFB385606809B6D144E56F07306FC"}}
{"primaryAccession": "Q9D7G9", "text": "This is MAPK-interacting and spindle-stabilizing protein protein, from Mouse, contains 263 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9D7G9", "organism_name": "Mouse", "protein_name": "MAPK-interacting and spindle-stabilizing protein", "length": 263, "firstPublicDate": "2003-07-11", "FUNCTION": "Involved in the maintenance of the spindle integrity during the cytostatic factor (CSF) arrest of oocytes", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the MISS family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MYPFIPPARLLPGSPAPFLPSGPSCPQPSGPYPGPAVRVPGPTRSYVSTNVPFPELPRPNSAPTDPVGPLGTQGSMSSGPWAPGMGGQHPNVPYLFPESSPTPPLPVSGAPPVAWVTVPPGAWEPPAQYPTPEASYPSPGLQPSPNNPYPLPPGPSAASPGPGSLHRMNEIPGGSPSDSSNPESTLESTGQKKHLKLDNKSIKRRRSKKKSKRVTWGDIKTLTHKAESLGKQQGHNTTDPKMMLLCLMTMLHVNSQHESEGSK", "length": 263, "molWeight": 27761, "crc64": "0D8B993796E9034E", "md5": "E840168795A1C7415EC91C289EC7E74E"}}
{"primaryAccession": "Q9D7K2", "text": "This is CST complex subunit TEN1 protein, from Mouse, contains 161 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9D7K2", "organism_name": "Mouse", "protein_name": "CST complex subunit TEN1", "length": 161, "firstPublicDate": "2010-03-23", "FUNCTION": "Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex, The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves, Initially the CST complex has been proposed to protect telomeres from DNA degradation (PubMed:19854130), However, the CST complex has been shown to be involved in several aspects of telomere replication, The CST complex inhibits telomerase and is involved in telomere length homeostasis; it is proposed to bind to newly telomerase-synthesized 3' overhangs and to terminate telomerase action implicating the association with the ACD:POT1 complex thus interfering with its telomerase stimulation activity, The CST complex is also proposed to be involved in fill-in synthesis of the telomeric C-strand probably implicating recruitment and activation of DNA polymerase alpha, The CST complex facilitates recovery from many forms of exogenous DNA damage; seems to be involved in the re-initiation of DNA replication at repaired forks and/or dormant origins (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TEN1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLPKPGVYYFPWEVSDGHVPEGSTLRTFGRLYLYDMARSLMTLAAPQKPDQCQLLVCTNLVEPFEAHVNFLYMVLGDLERMEGGAFVVRARLLTCVEGMDLSLLEKAILEQRRHLQKRQQPIGDASTLQTPTPAPQSIPSDSLSLEPENRGQQVPLPQTLD", "length": 161, "molWeight": 18066, "crc64": "4DACAD9187388A33", "md5": "9A77530C1B9455BAEC65CBBAF21EAB0A"}}
{"primaryAccession": "Q9EPK6", "text": "This is Nucleotide exchange factor SIL1 protein, from Mouse, contains 465 amino acids, is soluble, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9EPK6", "organism_name": "Mouse", "protein_name": "Nucleotide exchange factor SIL1", "length": 465, "firstPublicDate": "2006-02-21", "FUNCTION": "Required for protein translocation and folding in the endoplasmic reticulum (ER), Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the SIL1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAPQHLPSTRMASPGMLLGLLLTSCLTLCLSCQNSNNFALTNPEKSIHQESDTKETREEEELDTEILEVFHPTQEWQTLQPGQAVPAGSHVRMNLQTGVNEVKLQQEDKFQNNLKGFKRGRRLDINANTYTSQDLKSALAKFKEGTEMENSKDELARQATVKQLFRPIEELKKEFDELNVVLETDMQIMVRLINKFNSSSSSLEEKVAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATNQPLPAKKKVLFALCSLLRHFPYAQQQFLKLGGLQVLRSLVQEKSAKVLAVRVVTLLYDLVTEKMFAEEEAELTQDSSPEKLQQYRQVQLLPGLQEQGWCEITAQLLALPEHDAREKVLQTLGALLTTCRDRYRQDLQLSRTLGRLQAEYQALASLELQEGEDDGYFRELLASINSLMKELR", "length": 465, "molWeight": 52430, "crc64": "C3E2DB44394F1161", "md5": "906323721DFFCBD2319C211A34656A7F"}}
{"primaryAccession": "Q9ERU2", "text": "This is Zinc finger protein 22 protein, from Rat, contains 237 amino acids, has 5 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [55, 82], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [83, 110], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [111, 138], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [139, 166], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [167, 194], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9ERU2", "organism_name": "Rat", "protein_name": "Zinc finger protein 22", "length": 237, "firstPublicDate": "2004-03-15", "FUNCTION": "Binds DNA through the consensus sequence 5'-CAATG-3', May be involved in transcriptional regulation and may play a role in tooth formation (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 5}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRLGKPKGGISRSASQGKTYESKRKTARQRQKWGVAIRFDSGLSRRRRNVDEKPYKCTKCSKSFSQSSTLFQHKKIHTGKKSHKCADCGKSFFQSSNLIQHRRIHTGEKPYKCDECGERFKQSSNLIQHQRIHTGEKPYCCDECGRCFSQSSHLIQHQRTHTGEKPYQCEECDKCFSQSSHLRQHMKVHKEKKSHKRGKNARAKTHPVSWKRGKGRKAVAGLRQVKGAASGLFKKKK", "length": 237, "molWeight": 27286, "crc64": "9945E6C00AEC6624", "md5": "7495E11FA2669F19A3D1240CC4D9DB1D"}}
{"primaryAccession": "Q9EST4", "text": "This is Proteasome assembly chaperone 2 protein, from Mouse, contains 264 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9EST4", "organism_name": "Mouse", "protein_name": "Proteasome assembly chaperone 2", "length": 264, "firstPublicDate": "2008-02-26", "FUNCTION": "Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1, The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the PSMG2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFVPCGESVPDLTNFTLLMPAVSVGNVGQLAIDLIISTLNMCKIGYFYTDCLVPMVGNNPYATEEENSNELSINTEVYSLPSKKLVVLQLRSIFIKYKSKSFCEKLLAWVESSGCARIIVLSSSHSYHRNDAQLRSTPFRYLLTPCLQKSVQNKIKSLNWLEMEKSRCIPEMSDSEFCIRIPGGGITKTLYDESCSKEIQMAVLLKFVSEGDNIPDAVSLVEYLNEWLQIIKPCNDGPMASALPWKIPSSWRLLFGSGLPPALF", "length": 264, "molWeight": 29524, "crc64": "572AC760EDD7537E", "md5": "3D15C669C86F37EFF54B075ECF30A0B3"}}
{"primaryAccession": "Q9FI76", "text": "This is 1,4-dihydroxy-2-naphthoyl-CoA thioesterase 2 protein, from Mouse-ear cress, contains 157 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FI76", "organism_name": "Mouse-ear cress", "protein_name": "1,4-dihydroxy-2-naphthoyl-CoA thioesterase 2", "length": 157, "firstPublicDate": "2015-03-04", "FUNCTION": "Catalyzes the hydrolysis of the thioester bond of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) in peroxisomes, a necessary step to form the naphthoquinone ring of phylloquinone (vitamin K(1)), Displayed also slight thioesterase activity towards benzoyl-CoA, Is not active on phenylacetyl-CoA, succinyl-CoA and palmitoyl-CoA thioesters", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the 4-hydroxybenzoyl-CoA thioesterase family, DHNA-CoA hydrolase subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDPKSPEFIIDQPLKILGFVFDELSATRVSGHLTLTEKCCQPFKVLHGGVSALIAEALASLGAGIASGFKRVAGIHLSIHHLRPAALGEIVFAESFPVSVGKNIQVWEVRLWKAKKTETPDNKIMVSTSRVTLFCGLPIPDHVKDAPDELKKVISKL", "length": 157, "molWeight": 17063, "crc64": "F078ABECE9B3C35F", "md5": "74BB1ADCD6CE0BCF3242E2EB22E2418C"}}
{"primaryAccession": "Q9FJX3", "text": "This is Mitochondrial outer membrane protein porin 2 protein, from Mouse-ear cress, contains 276 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FJX3", "organism_name": "Mouse-ear cress", "protein_name": "Mitochondrial outer membrane protein porin 2", "length": 276, "firstPublicDate": "2011-12-14", "FUNCTION": "Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules, The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity), Involved in plant growth and development at the vegetative and reproductive stages, Is important for leaf and pollen development and mitochondrial membrane potential steady state, May be involved in ABA-mediated early seedling development and disease resistance", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the eukaryotic mitochondrial porin (TC 1,B,8,1) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSKGPGLFTDIGKKAKDLLTRDYNSDQKFSISTYSASGVALTSTALKKGGVHAADVATQYKYKNALFDVKIDTDSSVLTTVTLTEILPSTKAIASFKVPDYNSAKLEVQYFHDHATVTAAAALKQNPLIDITATLGSPVISFGAEAGYDTTSKTFTKYNAGISVTKPDACLSIILGDKGDSLKASYLHHFDEFKRTAAVGEVYRKFSTNENTITVGGLYAIDHSTAVKAKLNNHGTLGALLQHEVLPRSLVTVSSEIDTKALEKHPRFGLSLALKP", "length": 276, "molWeight": 29595, "crc64": "C0B0B35525D7D888", "md5": "1ED85BFC673276A094DBB627A6644152"}}
{"primaryAccession": "Q9FKB5", "text": "This is Cyclin-dependent kinase inhibitor 3 protein, from Mouse-ear cress, contains 222 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FKB5", "organism_name": "Mouse-ear cress", "protein_name": "Cyclin-dependent kinase inhibitor 3", "length": 222, "firstPublicDate": "2007-07-10", "FUNCTION": "Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity, May target specifically CDKA-1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CDI family, ICK/KRP subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGKYMKKSKITGDISVMEVSKATAPSPGVRTRAAKTLALKRLNSSAADSALPNDSSCYLQLRSRRLEKPSSLIEPKQPPRVHRSGIKESGSRSRVDSVNSVPVAQSSNEDECFDNFVSVQVSCGENSLGFESRHSTRESTPCNFVEDMEIMVTPGSSTRSMCRATKEYTREQDNVIPTTSEMEEFFAYAEQQQQRLFMEKYNFDIVNDIPLSGRYEWVQVKP", "length": 222, "molWeight": 24925, "crc64": "7A3EB2C9A29688A7", "md5": "D5C9100884919FADD2691FEE73597BDF"}}
{"primaryAccession": "Q9FKM2", "text": "This is Mitochondrial outer membrane protein porin 4 protein, from Mouse-ear cress, contains 274 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FKM2", "organism_name": "Mouse-ear cress", "protein_name": "Mitochondrial outer membrane protein porin 4", "length": 274, "firstPublicDate": "2011-12-14", "FUNCTION": "Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules, The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity), Involved in plant growth and development at the vegetative and reproductive stages, Is important for leaf and pollen development and mitochondrial membrane potential steady state, May be involved in disease resistance", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the eukaryotic mitochondrial porin (TC 1,B,8,1) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGSSPAPFADIGKKAKDLLNKDYIFDHKFTLTMLSATGTEFVATGLKKDDFFFGDISTLYKGQNTIVDLKIDSHSSVSTKVTLKNLLPSAKAVISFKIPDHKSGKLDVQYVHPHATLNSSIGLNPTPLLDLSATIGSQNVCLGGEVSFDTASSSLTKYNAGIGFNNQGVSAALILEDKGESLRATYVHTVNPTTSFGAELIRRFSNYNNSFTVGSSHSVDQFTVVKTRFSNSGKAGMVVQREWRPKSHITFSAEYDSKAVTSSPKLGLALALKP", "length": 274, "molWeight": 29505, "crc64": "20404992240902CF", "md5": "224C8CF3E0C94DCAE8BB2C33ED788C6F"}}
{"primaryAccession": "Q9FM85", "text": "This is Probable serine/threonine-protein kinase PBL16 protein, from Mouse-ear cress, contains 408 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FM85", "organism_name": "Mouse-ear cress", "protein_name": "Probable serine/threonine-protein kinase PBL16", "length": 408, "firstPublicDate": "2010-11-30", "FUNCTION": "May be involved in plant defense signaling", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the protein kinase superfamily, Ser/Thr protein kinase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGNCWCRFEPLNHRVSANAKSESPKEQSPTVEDKHIKEVQKLPSNPKEVEDLRRDSAANPLIAFTYEELKNITSNFRQDRVLGGGGFGSVYKGFIKEDLGDQEVPEPLPVAVKVHDGDNSFQGHREWLAEVIFLGQLSHPNLVKLIGYCCEDNHRVLIYEYMARGSVENNLFSRVLLPLSWAIRMKIAFGAAKGLAFLHEAKKPVIYRDFKTSNILLDMDYNAKLSDFGLAKDGPVGDKSHVSTRIMGTYGYAAPEYIMTGHLTPGSDVYSFGVVLLELLTGRKSLDKSRPTREQNLIDWALPLLKEKKKVLNIVDPKMNCEYPVKAVQKAAMLAYHCLNRNPKARPLMRDIVDSLEPLQATEEEALLVPPVQKAVITIIDEMPKNGLKKVEELKKVEEVKKVIEDAC", "length": 408, "molWeight": 45871, "crc64": "192BCDB2544F8166", "md5": "7114DA2F0195A70A793752674A8F952C"}}
{"primaryAccession": "Q9FNC9", "text": "This is Mitochondrial import receptor subunit TOM9-2 protein, from Mouse-ear cress, contains 99 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FNC9", "organism_name": "Mouse-ear cress", "protein_name": "Mitochondrial import receptor subunit TOM9-2", "length": 99, "firstPublicDate": "2002-10-19", "FUNCTION": "Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins, Together with TOM20 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the Tom22 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAKRIGAGKSGGGDPNILARISNSEIVSQGRRAAGDAVEVSKKLLRSTGKAAWIAGTTFLILVVPLIIEMDREAQINEIELQQASLLGAPPSPMQRGL", "length": 99, "molWeight": 10378, "crc64": "0D468E9A9153D263", "md5": "3AF4A70362CB405C09133A829DF06BE2"}}
{"primaryAccession": "Q9FNJ8", "text": "This is Arogenate dehydratase 5, chloroplastic protein, from Mouse-ear cress, contains 425 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FNJ8", "organism_name": "Mouse-ear cress", "protein_name": "Arogenate dehydratase 5, chloroplastic", "length": 425, "firstPublicDate": "2009-05-05", "FUNCTION": "Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQTISPAFSCDLKSVIQPNLTAKKARYSHVNGKRVSVRCSYRSESFSFPNGVGSSRADWQSSCAILASKVVSAENSSSVAVVNGHSNGSVDLSLVPSKSQHNGKPGLIQPLTITDLSPAPSHGSTLRVAYQGVPGAYSEAAAGKAYPNSEAIPCDQFDVAFQAVELWIADRAVLPVENSLGGSIHRNYDLLLRHRLHIVGEVQIPVHHCLLALPGVRTDCITRVISHPQALAQTEGSLNKLTPKAAIEAFHDTAAAAEYIAANNLHDTAAVASARAAELYGLQILADGIQDDAGNVTRFLMLARDPIIPRTDRPFKTSIVFAAQEHKGTSVLFKVLSAFAFRNISLTKIESRPHQNCPVRVVGDENVGTSKHFEYTFYVDFEASMAEARAQNALAEVQEYTSFLRVLGSYPMDMTPWSTLPSEDV", "length": 425, "molWeight": 45928, "crc64": "7B6AD16F3DE48B3F", "md5": "05D86C618C0E587FE36DB450458A5B98"}}
{"primaryAccession": "Q9FX83", "text": "This is NADH dehydrogenase [ubiquinone] iron-sulfur protein 8-B, mitochondrial protein, from Mouse-ear cress, contains 222 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FX83", "organism_name": "Mouse-ear cress", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8-B, mitochondrial", "length": 222, "firstPublicDate": "2011-06-28", "FUNCTION": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis, Complex I functions in the transfer of electrons from NADH to the respiratory chain, The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity), May donate electrons to ubiquinone", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the complex I 23 kDa subunit family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASLLARRSFSALRARHLAFSGQGLQGSHLCGLQSRAISYGSNKDDEEAEQLAKEISKDWSTVFERSMNTLFLTEMVRGLSLTLKYFFDPKVTINYPFEKGPLSPRFRGEHALRRYPTGEERCIACKLCEAVCPAQAITIEAEEREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETHEELLYDKEKLLENGDRWETEIAENLRSESLYR", "length": 222, "molWeight": 25378, "crc64": "64D8E9AFFF0BD5DD", "md5": "74DB944CE3767E10B1C87B8C09A4D87C"}}
{"primaryAccession": "Q9GU58", "text": "This is Conotoxin tx9a protein, from Cloth-of-gold cone, contains 88 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9GU58", "organism_name": "Cloth-of-gold cone", "protein_name": "Conotoxin tx9a", "length": 88, "firstPublicDate": "2002-07-26", "FUNCTION": "Neurotoxin, In vivo, intracranial injection into mice of 10 pmol/g of the peptide induces running in circles and hyperactivity, At higher doses (50 pmol/g), the mice exhibit running and climbing symptoms for close to one hour, Between 130 and 150 pmol/g, characteristic 'spasmodic' symptomatology is elicited, A hand clap would make mice jump high and start running rapidly, When exposed to a loud hand clap, or if the cage cover were dropped, the mice lose motor control and exhibit seizure-like symptoms from which they eventually recover, At the highest doses tested (over 250 pmol/g), after the characteristic spasmodic symptomatology, lethality occurs, Injection of a similar dose range intramuscularly into Siamese fighting fish elicited no unusual symptomatology", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the conotoxin P superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MHLSLARSAVLMLLLLFALGNFVVVQSGQITRDVDNGQLTDNRRNLQSKWKPVSLYMSRRGCNNSCQEHSDCESHCICTFRGCGAVNG", "length": 88, "molWeight": 9773, "crc64": "6C502E42A6C89E87", "md5": "F844E635B67A960C26428D8ADEC545D5"}}
{"primaryAccession": "Q9H069", "text": "This is Dynein regulatory complex subunit 3 protein, from Human, contains 523 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H069", "organism_name": "Human", "protein_name": "Dynein regulatory complex subunit 3", "length": 523, "firstPublicDate": "2006-03-21", "FUNCTION": "Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the DRC3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAFVEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISELFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEISISTLEKIVEGDLDEDLPNDLRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTRINSWCTRLIDRIHKDEIMRNRKRVKEINQYIDHMQSELDNLECGDILD", "length": 523, "molWeight": 61054, "crc64": "B36DF1E42318D768", "md5": "AAA2B0B9F041679294E69775581EDCA3"}}
{"primaryAccession": "Q9H0I3", "text": "This is Coiled-coil domain-containing protein 113 protein, from Human, contains 377 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H0I3", "organism_name": "Human", "protein_name": "Coiled-coil domain-containing protein 113", "length": 377, "firstPublicDate": "2007-03-06", "FUNCTION": "Component of centriolar satellites contributing to primary cilium formation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLAGK", "length": 377, "molWeight": 44220, "crc64": "6375CDF98733E33B", "md5": "AA90303D5B10BDFCC747F0FF41E80A2B"}}
{"primaryAccession": "Q9H9Y2", "text": "This is Ribosome production factor 1 protein, from Human, contains 349 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H9Y2", "organism_name": "Human", "protein_name": "Ribosome production factor 1", "length": 349, "firstPublicDate": "2005-07-19", "FUNCTION": "May be required for ribosome biogenesis", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAKAGDKSSSSGKKSLKRKAAAEELQEAAGAGDGATENGVQPPKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETTVDPNDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL", "length": 349, "molWeight": 40111, "crc64": "F939904B3AB79890", "md5": "B6432DADC48158409214999C3856B123"}}
{"primaryAccession": "Q9HBU9", "text": "This is Popeye domain-containing protein 2 protein, from Human, contains 364 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HBU9", "organism_name": "Human", "protein_name": "Popeye domain-containing protein 2", "length": 364, "firstPublicDate": "2003-10-31", "FUNCTION": "Important for the maintenance of cardiac function, Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the popeye family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSANSSRVGQLLLQGSACIRWKQDVEGAVYHLANCLLLLGFMGGSGVYGCFYLFGFLSAGYLCCVLWGWFSACGLDIVLWSFLLAVVCLLQLAHLVYRLREDTLPEEFDLLYKTLCLPLQVPLQTYKEIVHCCEEQVLTLATEQTYAVEGETPINRLSLLLSGRVRVSQDGQFLHYIFPYQFMDSPEWESLQPSEEGVFQVTLTAETSCSYISWPRKSLHLLLTKERYISCLFSALLGYDISEKLYTLNDKLFAKFGLRFDIRLPSLYHVLGPTAADAGPESEKGDEEVCEPAVSPPQATPTSLQQTPPCSTPPATTNFPAPPTRARLSRPDSGILASRIPLQSYSQVISRGQAPLAPTHTPEL", "length": 364, "molWeight": 40448, "crc64": "F29AA48CD611BE51", "md5": "0E854586EA1103A28CA2D040E45565BA"}}
{"primaryAccession": "Q9HGM4", "text": "This is Acyl-coenzyme A diphosphatase fit1 protein, from Fission yeast, contains 250 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HGM4", "organism_name": "Fission yeast", "protein_name": "Acyl-coenzyme A diphosphatase fit1", "length": 250, "firstPublicDate": "2009-05-05", "FUNCTION": "Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity), Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen (By similarity), This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis (By similarity), May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis (By similarity), May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation (By similarity), May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the FIT family, Fungal FIT2B/SCS3 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTEKTASHYWNEETSILKLRRKDILLFEIYATTLLLGSIYSIYVDKWSITSYFGNSKNLINLIFVKRGWFWTSLVYFYHAWDQKRNKIDFKFISRYIVATLWWMFVTQWFIGPGLIDRTFALSGGSCKNFDGDSSVFIPLTASTCKGLNGSWSGGHDLSGHVFLLTHSSLFMLSENFSFILNNGIKATSTKVLFGLLGLWWWMLFVTASFYHTTFEKCTGFFSGILEWSIVYVFSSRMPAVADLLGSSDY", "length": 250, "molWeight": 28787, "crc64": "ED485F5A03F29418", "md5": "A675783CA4C1522F17EC29FFD51FD713"}}
{"primaryAccession": "Q9JJN5", "text": "This is Carboxypeptidase N catalytic chain protein, from Mouse, contains 457 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JJN5", "organism_name": "Mouse", "protein_name": "Carboxypeptidase N catalytic chain", "length": 457, "firstPublicDate": "2005-10-11", "FUNCTION": "Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPDLPSAFLPLLLLSKFVTPVTFRHHRYDDLVRTLYKVHNQCPDITRLYNIGRSVKGRYLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNMSGYLVGRNNANGVDLNRNFPDLNTYFYYNSKNGGPNHHLPLPDNWKSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRGPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENSNNLTGAVISVTGINHDVTSGEHGDYFRLLLPGTYSVTAKAPGYDPKTVTVTVGPAGPTVVDFQLKRSSSQVYPVQRAPGRGQGGRAKQPRTSRKKDPATKRHRGPA", "length": 457, "molWeight": 51845, "crc64": "E36FEDA7B44FBC8F", "md5": "BA4F233EB8A6E717D973703F7637F8A4"}}
{"primaryAccession": "Q9JMB1", "text": "This is Testicular haploid expressed gene protein protein, from Mouse, contains 375 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9JMB1", "organism_name": "Mouse", "protein_name": "Testicular haploid expressed gene protein", "length": 375, "firstPublicDate": "2007-10-02", "FUNCTION": "May be involved (but not essential) in spermatogenesis", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGELGEHRASLLSNPIPEVKTLGELKQGQNNGNLDLESEPFGSHWLQGSKATTGRTSEEPEEEIPPEEMAGEELPETSNLDGPLQQDLEVEVVEMSHLSITERTPSVSTAKGRKKRSRRLLELAKPKTNWQCLRDRTGRCCKGYAWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPVVSQRMEELSRPKRFYQEYYNNNRTTPIWSIPRSTLEYQASNRLKQLATPKVRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRPPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLDVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELATPKYITKKV", "length": 375, "molWeight": 42796, "crc64": "0A03EEB94364EEA0", "md5": "7BEFD31BB973C87922A8A917F953A704"}}
{"primaryAccession": "Q9LFH9", "text": "This is L-type lectin-domain containing receptor kinase VIII.1 protein, from Mouse-ear cress, contains 715 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LFH9", "organism_name": "Mouse-ear cress", "protein_name": "L-type lectin-domain containing receptor kinase VIII.1", "length": 715, "firstPublicDate": "2011-01-11", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "In the N-terminal section; belongs to the leguminous lectin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSLFLSFFISILLCFFNGATTTQFDFSTLAISNLKLLGDARLSNGIVGLTRDLSVPNSGAGKVLYSNPIRFRQPGTHFPTSFSSFFSFSITNVNPSSIGGGLAFVISPDANSIGIAGGSLGLTGPNGSGSKFVAVEFDTLMDVDFKDINSNHVGFDVNGVVSSVSGDLGTVNIDLKSGNTINSWIEYDGLTRVFNVSVSYSNLKPKVPILSFPLDLDRYVNDFMFVGFSGSTQGSTEIHSIEWWSFSSSFGSSLGSGSGSPPPRANLMNPKANSVKSPPPLASQPSSSAIPISSNTQLKTSSSSSCHSRFCKENPGTIAGVVTAGAFFLALFAGALFWVYSKKFKRVERSDSFASEIIKAPKEFSYKELKAGTKNFNESRIIGHGAFGVVYRGILPETGDIVAVKRCSHSSQDKKNEFLSELSIIGSLRHRNLVRLQGWCHEKGEILLVYDLMPNGSLDKALFESRFTLPWDHRKKILLGVASALAYLHRECENQVIHRDVKSSNIMLDESFNAKLGDFGLARQIEHDKSPEATVAAGTMGYLAPEYLLTGRASEKTDVFSYGAVVLEVVSGRRPIEKDLNVQRHNVGVNPNLVEWVWGLYKEGKVSAAADSRLEGKFDEGEMWRVLVVGLACSHPDPAFRPTMRSVVQMLIGEADVPVVPKSRPTMSFSTSHLLLSLQDTLSDCNTVALNSSRSSSWSVPEHNVIIRSDDDHLV", "length": 715, "molWeight": 77672, "crc64": "AD2C1AC8C14DD55A", "md5": "D3347E36C448D44F73B030B5EBBD85E2"}}
{"primaryAccession": "Q9LJR2", "text": "This is Lectin-like protein LEC protein, from Mouse-ear cress, contains 271 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LJR2", "organism_name": "Mouse-ear cress", "protein_name": "Lectin-like protein LEC", "length": 271, "firstPublicDate": "2014-05-14", "FUNCTION": "Plays a role in defense responses triggered by jasmonate, ethylene and chitin", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the leguminous lectin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQIHKLCFLALFLANAAFAVKFNFDSFDGSNLLFLGDAELGPSSDGVSRSGALSMTRDETPFSHGQGLYINPIQFKSSNTSSPFDFKTSFTFSITPRTKPNSGQGLAFVIVPAADNSGASGGGYLGILNKTNDGKSENNLIFIEFDTFKNNESNDISGNHVGININSMTSLVAEKAGYWVQTLVGKRKVWSFKDVNLSSGERFKAWIEFRSKDSRNTITIAPENVKKPKRPLIQGSRVLNDVLLQNMYAGFAGSMGRAGERHDVWSWSFEN", "length": 271, "molWeight": 29749, "crc64": "B411709DCF58DB9A", "md5": "74D92F63AD8308BB7C2DC32F9B41A9C0"}}
{"primaryAccession": "Q9LKA4", "text": "This is UBP1-associated protein 2C protein, from Mouse-ear cress, contains 404 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LKA4", "organism_name": "Mouse-ear cress", "protein_name": "UBP1-associated protein 2C", "length": 404, "firstPublicDate": "2014-02-19", "FUNCTION": "Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as component of a complex regulating the turnover of mRNAs in the nucleus, Binds with high affinity to RNA molecules that contain U-rich sequences in 3'-UTRs, May function in complex with UBP1 and contribute to the stabilization of mRNAs in the nucleus (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDMMKKRKLDENGNGLNTNGGGTIGPTRLSPQDARKIIERFTTDQLLDLLQEAIVRHPDVLESVRLTADSDISQRKLFIRGLAADTTTEGLRSLFSSYGDLEEAIVILDKVTGKSKGYGFVTFMHVDGALLALKEPSKKIDGRVTVTQLAASGNQGTGSQIADISMRKIYVANVPFDMPADRLLNHFMAYGDVEEGPLGFDKVTGKSRGFALFVYKTAEGAQAALADPVKVIDGKHLNCKLAVDGKKGGKPGMPQAQDGGSGHGHVHGEGMGMVRPAGPYGAAGGISAYGGYSGGPPAHHMNSTHSSMGVGSAGYGGHYGGYGGPGGTGVYGGLGGGYGGPGTGSGQYRMPPSSMPGGGGYPESGHYGLSSSAGYPGQHHQAVGTSPVPRVPHGGMYPNGPPNY", "length": 404, "molWeight": 41780, "crc64": "867DCDA90A0DFEB2", "md5": "05F9DC455842931EC134A7F8D9E8D995"}}
{"primaryAccession": "Q9LKX9", "text": "This is Retinoblastoma-related protein 1 protein, from Maize, contains 867 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LKX9", "organism_name": "Maize", "protein_name": "Retinoblastoma-related protein 1", "length": 867, "firstPublicDate": "2008-05-20", "FUNCTION": "Regulator of biological processes that recruits a histone deacetylase to control gene transcription, May play a role in the entry into mitosis, negatively regulating the cell proliferation, Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the retinoblastoma protein (RB) family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSLDPSPATSTQQQKQLESLVNLLTQGSRFYRKAYNELFSGVTTEQDPDSSTNIPEYMLFGWHLFLMLHLRSPELFKDLVSCIHGLVAVLAILLIHVPAKFRSFTIEGSSHLIKQTEKGVDLIASLCHNYHTSEERLKEMLHKSHNAIEDIFHMKALSASECKPENLDKIDTDDLMYFKGLIDMECFQSNLEKMEKLCNSNSCKGELDFKSILINNDYIPYDENSTGDSTNLGHSKCAFETLASPTKTIKNMLTVPSSPLSPATGGSVKIVQMTPVTSAMTTAKWLREVISSLPDKPSSKLQQFLSSCDRDLTNAVTERVSIVLEAIFPTKSSANRGVSLGLNCANAFDIPWAEARKVEASKLYYRVLEAICRAELQNSNVNNLTPLLSNERFHRCLIACSADLVLATHKTVIMMFPAVLESTGLTAFDLSKIIENFVRHEETLPRELKRHLNSLEEQLLESMAWEKGSSLYNSLIVARPSVASEINRLGLLAEPMPSLDDLVSRQNVRIEGLPATPSKKRAAGPDDNADPRSPKRSCNESRNTVVERNLQTPPPKQSHMVSTSLKAKCHPLQSTFASPTVCNPVGGNEKCADVTIHIFFSKILKLAAIRIRNLCERVQCVEQTERVYNVFKQILEQQTTLFFNRHIDQLILCCLYGVAKVCQLELTFREILNNYKREAQCKPEVFSSIYIGSTNRNGVLVSRHVGIITFYNEVFVPAAKPFLVSLISSGTHPEDKKNASGQIPGSPKPSPFPNLPDMSPKKVSASHNVYVSPLRQTKLDLLLSPSSRSFYACIGEGTHAYQSPSKDLAAINSRLNYNGRKVNSRLNFDMVSDSVVAGSLGQINGGSTSDPAAAFSPLSKKRETDT", "length": 867, "molWeight": 96200, "crc64": "3B2DB7A1E5A3BEEF", "md5": "97D6696DD260FBFF22067F5803E9CE5D"}}
{"primaryAccession": "Q9LM71", "text": "This is Peptidyl-prolyl cis-trans isomerase FKBP18, chloroplastic protein, from Mouse-ear cress, contains 232 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LM71", "organism_name": "Mouse-ear cress", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP18, chloroplastic", "length": 232, "firstPublicDate": "2001-09-26", "FUNCTION": "PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the FKBP-type PPIase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASISSLHRWASNQHSRLPRITSISEADQSRPINQVVAFSVPISRRDASIILLSSIPLTSFFVLTPSSSEARERRSRKVIPLEEYSTGPEGLKFYDIEEGKGPVATEGSTAQVHFDCRYRSITAISTRESKLLAGNRSIAQPYEFKVGSTPGKERKREFVDNPNGLFSAQAAPKPPPAMYFITEGMKVGGKRTVIVPPEAGYGQKGMNEIPPGATFELNIELLRVTPPPEEK", "length": 232, "molWeight": 25530, "crc64": "DD6EAE3E24247061", "md5": "12E496839344E72015CF1654831AE18B"}}
{"primaryAccession": "Q9LMR3", "text": "This is Arogenate dehydrogenase 2, chloroplastic protein, from Mouse-ear cress, contains 358 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LMR3", "organism_name": "Mouse-ear cress", "protein_name": "Arogenate dehydrogenase 2, chloroplastic", "length": 358, "firstPublicDate": "2007-01-09", "FUNCTION": "Involved in the biosynthesis of tyrosine, Has a weak prephenate dehydrogenase activity", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the prephenate/arogenate dehydrogenase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLLHFSPAKPLISPPNLRRNSPTFLISPPRSLRIRAIDAAQIFDYETQLKSEYRKSSALKIAVLGFGNFGQFLSKTLIRHGHDLITHSRSDYSDAANSIGARFFDNPHDLCEQHPDVVLLCTSILSTESVLRSFPFQRLRRSTLFVDVLSVKEFPKALFIKYLPKEFDILCTHPMFGPESGKHSWSGLPFVYDKVRIGDAASRQERCEKFLRIFENEGCKMVEMSCEKHDYYAAGSQFVTHTMGRVLEKYGVESSPINTKGYETLLDLVENTSSDSFELFYGLFMYNPNALEQLERLDMAFESVKKELFGRLHQQYRKQMFGGEVQSPKKTEQKLLNDGGVVPMNDISSSSSSSSSSS", "length": 358, "molWeight": 40633, "crc64": "DCEFA72C62D1AF78", "md5": "B952A3436C59EE91F7B7E07BAE0F7AEB"}}
{"primaryAccession": "Q9LQU4", "text": "This is Protein PLANT CADMIUM RESISTANCE 2 protein, from Mouse-ear cress, contains 152 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LQU4", "organism_name": "Mouse-ear cress", "protein_name": "Protein PLANT CADMIUM RESISTANCE 2", "length": 152, "firstPublicDate": "2007-09-11", "FUNCTION": "Zinc transporter acting in both zinc extrusion and long-distance zinc transport, Involved in the loading of zinc into the xyleme and in the detoxification of excess zinc at the epidermal cells, Acts independently from the zinc transporters HMA2 and HMA4, May be also involved in cadmium resistance", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the cornifelin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEAQHLHAKPHAEGEWSTGFCDCFSDCKNCCITFWCPCITFGQVAEIVDRGSTSCGTAGALYALIAVVTGCACIYSCFYRGKMRAQYNIKGDDCTDCLKHFCCELCSLTQQYRELKHRGYDMSLGWAGNVERQQNQGGVAMGAPVFQGGMTR", "length": 152, "molWeight": 16742, "crc64": "BC0655E747D315D1", "md5": "F0BF7CBCC8815D78EC083DB996920BFF"}}
{"primaryAccession": "Q9LRY0", "text": "This is Cyclin-dependent kinase inhibitor 5 protein, from Mouse-ear cress, contains 189 amino acids, is soluble, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LRY0", "organism_name": "Mouse-ear cress", "protein_name": "Cyclin-dependent kinase inhibitor 5", "length": 189, "firstPublicDate": "2007-07-10", "FUNCTION": "Inhibits CYCD2-1/CDKA-1 complex kinase activity without interaction with the complex", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the CDI family, ICK/KRP subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGKYIKKSKVAGAVSVKDKSHPPALGFRTRAAAAKNLALHRLRSHSDEADSFNYLQLRSRRLVKLPLLTNTRKQQKQQLIPSVNQCQTKNPRASSGPAKKLEPDTTTEEACGDNERISRSDCNFGDKGFDLESENRSMISDSKSIQSEIEDFFASAEQQQQRFFIQKYNFDIVSDNPLPGRYEWVKVMP", "length": 189, "molWeight": 21424, "crc64": "A66041310E8DDED6", "md5": "BE8665A3884C2203F16B533990AC0C93"}}
{"primaryAccession": "Q9LU21", "text": "This is Photosynthetic NDH subunit of subcomplex B 3, chloroplastic protein, from Mouse-ear cress, contains 204 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LU21", "organism_name": "Mouse-ear cress", "protein_name": "Photosynthetic NDH subunit of subcomplex B 3, chloroplastic", "length": 204, "firstPublicDate": "2015-02-04", "FUNCTION": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain, The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone, Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGSVQLSGSGLVASLPPNHSFSHKTKLNKPNSYFFRSKHNAARTKTVRAISTAPASQPPAADEPDEPPAVDFAFVHSVLLPDGTPDVHWRRANGGQKLRDIMLDSNIELYGPYSKPLSNCAGVGTCATCMVEIVNGKELLNPRTDIEKEKLKRKPKNWRLACQTNVGNPDSTGLVVIQQLPEWKAHEWNIPKNIPNDDDLETST", "length": 204, "molWeight": 22418, "crc64": "393C457756AF1B02", "md5": "368E9EED6EE4F755ABF576BCD225073F"}}
{"primaryAccession": "Q9LW68", "text": "This is Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 4 protein, from Mouse-ear cress, contains 195 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LW68", "organism_name": "Mouse-ear cress", "protein_name": "Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 4", "length": 195, "firstPublicDate": "2014-02-19", "FUNCTION": "Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light (By similarity), May suppress organ differentiation in the boundary region", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the plant homeotic and developmental regulators ALOG protein family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDHIIGFMGTTNMSHNTNLMIAAAATTTTTSSSSSSSSGGSGTNQLSRYENQKRRDWNTFGQYLRNHRPPLSLSRCSGAHVLEFLRYLDQFGKTKVHTHLCPFFGHPNPPAPCACPLRQAWGSLDALIGRLRAAFEENGGSPETNPFGARAVRLYLREVRDSQAKARGISYEKKKRKRPPPPLPPAQPAISSSPN", "length": 195, "molWeight": 21434, "crc64": "A6BA85958BEFCE23", "md5": "8CB5D8FA9352A629500F31BAE09EEDA3"}}
{"primaryAccession": "Q9LX82", "text": "This is Transcription factor MYB48 protein, from Mouse-ear cress, contains 256 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LX82", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor MYB48", "length": 256, "firstPublicDate": "2006-05-16", "FUNCTION": "Transcription factor", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMQEEGNRKGPWTEQEDILLVNFVHLFGDRRWDFIAKVSGLNRTGKSCRLRWVNYLHPGLKRGKMTPQEERLVLELHAKWGNRWSKIARKLPGRTDNEIKNYWRTHMRKKAQEKKRPVSPTSSFSNCSSSSVTTTTTNTQDTSCHSRKSSGEVSFYDTGGSRSTREMNQENEDVYSLDDIWREIDHSAVNIIKPVKDIYSEQSHCLSYPNLASPSWESSLDSIWNMDADKSKISSYFANDQFPFCFQHSRSPWSSG", "length": 256, "molWeight": 29654, "crc64": "A872DFB58AC8379F", "md5": "3CFC82898CB58DA6A765B5531BF4AF81"}}
{"primaryAccession": "Q9LYG9", "text": "This is Mechanosensitive ion channel protein 10 protein, from Mouse-ear cress, contains 734 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LYG9", "organism_name": "Mouse-ear cress", "protein_name": "Mechanosensitive ion channel protein 10", "length": 734, "firstPublicDate": "2007-12-04", "FUNCTION": "Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the MscS (TC 1,A,23) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAEQKSSNGGGGGGDVVINVPVEEASRRSKEMASPESEKGVPFSKSPSPEISKLVGSPNKPPRAPNQNNVGLTQRKSFARSVYSKPKSRFVDPSCPVDTSILEEEVREQLGAGFSFSRASPNNKSNRSVGSPAPVTPSKVVVEKDEDEEIYKKVKLNREMRSKISTLALIESAFFVVILSALVASLTINVLKHHTFWGLEVWKWCVLVMVIFSGMLVTNWFMRLIVFLIETNFLLRRKVLYFVHGLKKSVQVFIWLCLILVAWILLFNHDVKRSPAATKVLKCITRTLISILTGAFFWLVKTLLLKILAANFNVNNFFDRIQDSVFHQYVLQTLSGLPLMEEAERVGREPSTGHLSFATVVKKGTVKEKKVIDMGKVHKMKREKVSAWTMRVLMEAVRTSGLSTISDTLDETAYGEGKEQADREITSEMEALAAAYHVFRNVAQPFFNYIEEEDLLRFMIKEEVDLVFPLFDGAAETGRITRKAFTEWVVKVYTSRRALAHSLNDTKTAVKQLNKLVTAILMVVTVVIWLLLLEVATTKVLLFFSTQLVALAFIIGSTCKNLFESIVFVFVMHPYDVGDRCVVDGVAMLVEEMNLLTTVFLKLNNEKVYYPNAVLATKPISNYFRSPNMGETVEFSISFSTPVSKIAHLKERIAEYLEQNPQHWAPVHSVVVKEIENMNKLKMALYSDHTITFQENRERNLRRTELSLAIKRMLEDLHIDYTLLPQDINLTKKN", "length": 734, "molWeight": 83032, "crc64": "ACE37655EEFFC149", "md5": "85D7AA8D4CE077478A27CB09BBCB0B12"}}
{"primaryAccession": "Q9LYR5", "text": "This is Peptidyl-prolyl cis-trans isomerase FKBP19, chloroplastic protein, from Mouse-ear cress, contains 256 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LYR5", "organism_name": "Mouse-ear cress", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP19, chloroplastic", "length": 256, "firstPublicDate": "2008-07-01", "FUNCTION": "PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the FKBP-type PPIase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASISSFGCFPQSTALAGTSSTTRCRTTVAARLADQSDDFAPLRSSGGNCGCVNNSGEFDRRKLLVSSVGLLIGALSYDSKDGDFASASQFADMPALKGKDYGKTKMKYPDYTETQSGLQYKDLRVGTGPIAKKGDKVVVDWDGYTIGYYGRIFEARNKTKGGSFEGDDKEFFKFTLGSNEVIPAFEEAVSGMALGGIRRIIVPPELGYPDNDYNKSGPRPMTFSGQRALDFVLRNQGLIDKTLLFDVELLKIVPN", "length": 256, "molWeight": 27778, "crc64": "30CBBE141BDDB8A0", "md5": "B6F0043E73FCB3DFDC44F999AC1906DA"}}
{"primaryAccession": "Q9M047", "text": "This is LIM domain-containing protein WLIM2b protein, from Mouse-ear cress, contains 199 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M047", "organism_name": "Mouse-ear cress", "protein_name": "LIM domain-containing protein WLIM2b", "length": 199, "firstPublicDate": "2014-10-29", "FUNCTION": "Binds to actin filaments and promotes cross-linking into thick bundles, Has an actin-stabilizing activity, The actin regulatory activities are not regulated by pH and [Ca(2+)]", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSFTGTQQKCKACEKTVYAVELLSADGVGYHKSCFKCTHCKSRLQLSSYSSMEGVLYCKPHFEQLFKESGSFNKNFQSPAKSADKSTPELTRTPSRVAGRFSGTQEKCATCSKTVYPIEKVTVESQTYHKSCFKCSHGGCPISPSNYAALEGILYCKHHFAQLFKEKGSYNHLIKSASIKRSAAAAVAAGVPAASVPES", "length": 199, "molWeight": 21664, "crc64": "25AD823DBB2C567C", "md5": "09D7F2516EFCE32BD03659D26136A1BA"}}
{"primaryAccession": "Q9M0S5", "text": "This is Isoamylase 3, chloroplastic protein, from Mouse-ear cress, contains 764 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M0S5", "organism_name": "Mouse-ear cress", "protein_name": "Isoamylase 3, chloroplastic", "length": 764, "firstPublicDate": "2009-07-07", "FUNCTION": "Involved in starch catabolism, ISA3 removes different branches than ISA1-ISA2, namely short chains that prevent amylopectin crystallization, May be the debranching enzyme required to assist beta-amylases for starch degradation in leaves at night", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the glycosyl hydrolase 13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLTSPSSSSTYDPFSSNFSPSLTNAFSSSFTIPMGLKLSRRVTRARIFSRKIKDRSTLKVTCRRAHERVVEEEASTMTETKLFKVSSGEVSPLGVSQVDKGINFALFSQNATSVTLCLSLSQSGKDDTDDDGMIELVLDPSVNKTGDTWHICVEDLPLNNVLYGYRVDGPGEWQQGHRFDRSILLLDPYAKLVKGHSSFGDSSQKFAQFYGTYDFESSPFDWGDDYKFPNIPEKDLVIYEMNVRAFTADESSGMDPAIGGSYLGFIEKIPHLQDLGINAVELLPVFEFDELELQRRSNPRDHMVNTWGYSTVNFFAPMSRYASGEGDPIKASKEFKEMVKALHSAGIEVILDVVYNHTNEADDKYPYTTSFRGIDNKVYYMLDPNNQLLNFSGCGNTLNCNHPVVMELILDSLRHWVTEYHVDGFRFDLASVLCRATDGSPLSAPPLIRAIAKDSVLSRCKIIAEPWDCGGLYLVGKFPNWDRWAEWNGMYRDDVRRFIKGDSGMKGSFATRVSGSSDLYQVNQRKPYHGVNFVIAHDGFTLRDLVSYNFKHNEANGEGGNDGCNDNHSWNCGFEGETGDAHIKSLRTRQMKNFHLALMISQGTPMMLMGDEYGHTRYGNNNSYGHDTSLNNFQWKELDAKKQNHFRFFSEVIKFRHSHHVLKHENFLTQGEITWHEDNWDNSESKFLAFTLHDGIGGRDIYVAFNAHDYFVKALIPQPPPGKQWFRVADTNLESPDDFVREGVAGVADTYNVAPFSSILLQSK", "length": 764, "molWeight": 86322, "crc64": "EE9F163AE7F5E052", "md5": "39675D5C27934A33AFBEEECBDD4D81B1"}}
{"primaryAccession": "Q9M2Q6", "text": "This is Squamosa promoter-binding-like protein 15 protein, from Mouse-ear cress, contains 354 amino acids, has 1 SBP-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [56, 133], "description": "SBP-type", "keyword_description": "Zinc finger", "textural_description": "SBP-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9M2Q6", "organism_name": "Mouse-ear cress", "protein_name": "Squamosa promoter-binding-like protein 15", "length": 354, "firstPublicDate": "2005-06-07", "FUNCTION": "Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"SBP-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MELLMCSGQAESGGSSSTESSSLSGGLRFGQKIYFEDGSGSRSKNRVNTVRKSSTTARCQVEGCRMDLSNVKAYYSRHKVCCIHSKSSKVIVSGLHQRFCQQCSRFHQLSEFDLEKRSCRRRLACHNERRRKPQPTTALFTSHYSRIAPSLYGNPNAAMIKSVLGDPTAWSTARSVMQRPGPWQINPVRETHPHMNVLSHGSSSFTTCPEMINNNSTDSSCALSLLSNSYPIHQQQLQTPTNTWRPSSGFDSMISFSDKVTMAQPPPISTHQPPISTHQQYLSQTWEVIAGEKSNSHYMSPVSQISEPADFQISNGTTMGGFELYLHQQVLKQYMEPENTRAYDSSPQHFNWSL", "length": 354, "molWeight": 39672, "crc64": "F844ED9DFC69CE85", "md5": "8C06AC201CE8B754B77B4115E37EF55D"}}
{"primaryAccession": "Q9M365", "text": "This is Probable F-box protein At3g61730 protein, from Mouse-ear cress, contains 359 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M365", "organism_name": "Mouse-ear cress", "protein_name": "Probable F-box protein At3g61730", "length": 359, "firstPublicDate": "2010-08-10", "FUNCTION": "Regulates tapetum degeneration and pollen maturation during anther development", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKTRSSDAEGDSRGKMIAPVGEGNGGRKRKLVQSNEQKNDIQREEDGRAKRRIVQSSDQKNGKILRGIRGCVSPRCSAQTYQSRFSWYEQDIWTYISRFLDGKSLVKLGATNKWFYKIAMEDTVWRFACLRDLQVPVPFPVSSTWIKIYASAFDGSHSYLFRQKEKHIDWMRIGAFVLDSRTSLLTESLSGRLKFPREGTIERMLQSSGSCLINDIKSGIWIADLQLVRCPVCDLSTCDGTMQTLDARHIELFLSEGYKDGSWDYNLIGSHKLQKNASAACGAIFDLKHLKESSYSGILNLKSWTGESNDSQPKAVIAPHAVAVHTRLQENEGILVKYHTMKAGTDGDIVSIRISQQLL", "length": 359, "molWeight": 40452, "crc64": "7BFDD6797969B356", "md5": "AB2ACFA4DFC5782F58E8271EB5D093AB"}}
{"primaryAccession": "Q9M424", "text": "This is Neoxanthin synthase, chloroplastic protein, from Potato, contains 498 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M424", "organism_name": "Potato", "protein_name": "Neoxanthin synthase, chloroplastic", "length": 498, "firstPublicDate": "2009-10-13", "FUNCTION": "Involved in the synthesis of neoxanthin, the last product of carotenoid synthesis and a precursor of abscisic acid", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the lycopene cyclase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "METLLKPLTSLLLSSPTPHRSIFQQNPPSLNPTTKKKSRKCHFRNESSKLFCSFLDLAPISKPESFDVNISLVDPNSGRAQFDVIIIGAGPAGLRLAEHVSKYGIKVCCVDPSPLSMWPNNYGVWVDEFENLGLEDCLDHKWPMTCVHINDHKTKYLGRPYGRVSRKKLKLRLLNSCVENRVKFYKAKVWKVEHEEFESSIVCDDGKKIRGSLVVDASGFASDFIEYDKPRNHGYQIAHGVLVEVDNHPFDLDKMVLMDWRDSHLGNEPYLRVNNAKEPTFLYAMPFDRNLVFLEETSLVSRPVLSYMEVKRRMVARLRHLGIKVRSVIEEEKCVIPMGGPLPRIPQNVMAIGGNSGIVHPSTGYMVARSMALAPVLAEAIVKGLGSTRMIRGSQLYHRVWNGLWPLDRRCIGECYSFGMETLLKLDLKGTRRLFDAFFDLDPKYWQGFLSSRLSVKELAILSLCLFGHGSNLTRLDIVTKCPVPLVRLIGNLAIESL", "length": 498, "molWeight": 56357, "crc64": "0CAB552D958C6F26", "md5": "CA5C85D524D65E579010087664827E48"}}
{"primaryAccession": "Q9M9V6", "text": "This is Isochorismate synthase 2, chloroplastic protein, from Mouse-ear cress, contains 562 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M9V6", "organism_name": "Mouse-ear cress", "protein_name": "Isochorismate synthase 2, chloroplastic", "length": 562, "firstPublicDate": "2008-07-22", "FUNCTION": "Isochorismate synthase involved in the synthesis of salicylic acid (SA) required for both local and systemic acquired resistance (LAR and SAR) while SA synthesized through the phenylalanine ammonium lyase (PAL) pathway seems to potentiate plant cell death, Also involved in phylloquinone (vitamin K1) synthesis, Has no isochorismate pyruvate lyase (IPL) activity", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the isochorismate synthase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASLQCSFHFLGTNPKKYNPSSIFQSYSRTSFTKLSSRVSRQRFLRCTLSMNGCEADHKAPLGTVETRTLSTVPSPAAATERLITAVSDLKSQPPPFSSGIVRLQVPIEQKIGAIDWLHAQNEILPRSFFSRRSDSGRPDLLQDFSSDNGSSDHNPVSVAGIGSAVFFRDLDPFSHDDWRSIRRFLSSKSPLIRAYGGLRFDPTGKIAVEWEHFGSFYFTVPQVEFDEFGGSSMLAATVAWDNELSWTLENAIEALQETMLQVSSVIMRLRRESLGVIVVSKNHVPSEGAYYPAVNNALEIIKDKHSPLSKVVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAFIGNTPERLFHRKHLGVCSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKSVRKLARVQHLYSQLAGQLKREDDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGMYAGPIGFFGGGESEFSVGIRSALVEKGLGALIYAGTGIVSGSNPSSEWNELELKISQFTKSLEHESALQPIN", "length": 562, "molWeight": 62386, "crc64": "05454B7F8124331C", "md5": "451F369584CE20701A6B8BE0A5684E56"}}
{"primaryAccession": "Q9NRN5", "text": "This is Olfactomedin-like protein 3 protein, from Human, contains 406 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NRN5", "organism_name": "Human", "protein_name": "Olfactomedin-like protein 3", "length": 406, "firstPublicDate": "2003-10-24", "FUNCTION": "Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development, Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side, Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity), May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the OLFML3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGPSTPLLILFLLSWSGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRDFKNKMLPLLEVAEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEKVTGGPGTKGKGRRNEKYDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLANRTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV", "length": 406, "molWeight": 46010, "crc64": "0B5DB1A803BB99D6", "md5": "A77C3087AC6F930D28A6CDE9F0187A4B"}}
{"primaryAccession": "Q9NRR1", "text": "This is Cytokine-like protein 1 protein, from Human, contains 136 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NRR1", "organism_name": "Human", "protein_name": "Cytokine-like protein 1", "length": 136, "firstPublicDate": "2002-06-06", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRTPGPLPVLLLLLAGAPAARPTPPTCYSRMRALSQEITRDFNLLQVSEPSEPCVRYLPRLYLDIHNYCVLDKLRDFVASPPCWKVAQVDSLKDKARKLYTIMNSFCRRDLVFLLDDCNALEYPIPVTTVLPDRQR", "length": 136, "molWeight": 15577, "crc64": "1CAEE1BFC31A3AE3", "md5": "6FF339170B019204634B61568E1F3AB6"}}
{"primaryAccession": "Q9NVR2", "text": "This is Integrator complex subunit 10 protein, from Human, contains 710 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NVR2", "organism_name": "Human", "protein_name": "Integrator complex subunit 10", "length": 710, "firstPublicDate": "2006-05-16", "FUNCTION": "Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable), May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex (PubMed:23904267)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Integrator subunit 10 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAGRLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTEQCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLPLIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKYIIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDSEAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEIDRNKHIHKKRKLAEGREKTMSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARESWELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSISQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSKVKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPRGENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLT", "length": 710, "molWeight": 82236, "crc64": "3E9945064EC4BEFB", "md5": "AFAB3BEA5E2701AC84F225B1C49D7A9F"}}
{"primaryAccession": "Q9NVS2", "text": "This is Large ribosomal subunit protein mL66 protein, from Human, contains 196 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NVS2", "organism_name": "Human", "protein_name": "Large ribosomal subunit protein mL66", "length": 196, "firstPublicDate": "2002-10-19", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bS18 family, Mitochondrion-specific ribosomal protein mL66 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAALKALVSGCGRLLRGLLAGPAATSWSRLPARGFREVVETQEGKTTIIEGRITATPKESPNPPNPSGQCPICRWNLKHKYNYDDVLLLSQFIRPHGGMLPRKITGLCQEEHRKIEECVKMAHRAGLLPNHRPRLPEGVVPKSKPQLNRYLTRWAPGSVKPIYKKGPRWNRVRMPVGSPLLRDNVCYSRTPWKLYH", "length": 196, "molWeight": 22184, "crc64": "CC086B8FC27242D6", "md5": "F4D5730E7B003190494E9CCB2CD2A5F1"}}
{"primaryAccession": "Q9NX20", "text": "This is Large ribosomal subunit protein uL16m protein, from Human, contains 251 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9NX20", "organism_name": "Human", "protein_name": "Large ribosomal subunit protein uL16m", "length": 251, "firstPublicDate": "2006-06-13", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL16 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MWRLLARASAPLLRVPLSDSWALLPASAGVKTLLPVPSFEDVSIPEKPKLRFIERAPLVPKVRREPKNLSDIRGPSTEATEFTEGNFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFAIWRVPAPFKPITRKSVGHRMGGGKGAIDHYVTPVKAGRLVVEMGGRCEFEEVQGFLDQVAHKLPFAAKAVSRGTLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGKYWGKFYMPKRV", "length": 251, "molWeight": 28449, "crc64": "8A42A67DA80A6FEF", "md5": "C7A486CB818DFC01783287ED1727AD5A"}}
{"primaryAccession": "Q9P546", "text": "This is Small ribosomal subunit protein uS2B protein, from Fission yeast, contains 287 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P546", "organism_name": "Fission yeast", "protein_name": "Small ribosomal subunit protein uS2B", "length": 287, "firstPublicDate": "2001-08-14", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (By similarity), uS2 is required for the assembly and/or stability of the 40S ribosomal subunit, Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (PubMed:14623272)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the universal ribosomal protein uS2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAESIARPSVLNATDDDIKNLLAADSHIGSKNLEVRMENYVWKRRSDGIHIINLGKTWEKLVLAARVIATIENPADVCVISSRPYGHRAVLKFAAHTGATAIAGRFTPGNFTNYITRTYREPRLIIVTDPRADAQAIKEASFVNIPVIALCDTDSILNHVDVAIPINNKGYKSIGLAWYLLAREVLRLRGNISRTTAWEVMPDLYFYRDPEEIEREEEQKAAAAAAAEEEAQLAAQTAAAEFEVTDSAAGTVDPTILDNATAGQVGQTTWEGDAEWNITGAAPSEWA", "length": 287, "molWeight": 31420, "crc64": "2D3D13FDA6788C66", "md5": "CD10D40292278E24B66BA49567AF1BC8"}}
{"primaryAccession": "Q9P7J2", "text": "This is Xrcc4-like factor 1 protein, from Fission yeast, contains 203 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7J2", "organism_name": "Fission yeast", "protein_name": "Xrcc4-like factor 1", "length": 203, "firstPublicDate": "2004-07-19", "FUNCTION": "Involved in non-homologous end joining (NHEJ) in the repair of double-strand DNA breaks (DSB), Has a role in meiosis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the XRCC4-XLF family, XLF subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSWVQLRGHRFHFIQASFDAESNEAVQVIHITDLVRVWSCTCSRNQIVNQAESERCPIDPFQTFETLVDVLAEVLVNVSSESRIQLRGSNDEGSLKIFCTSKIAKDIFLEWNWTLWLTPPETIAKMVWFPLINHHLFESETDTSPGSLMSIIRDQKSLLNDKTWFKEALNERSSSSNPSTPRKRSAFADIISPKRPRTRYDFV", "length": 203, "molWeight": 23434, "crc64": "00094EB0FBCA0E43", "md5": "FF8DBC738C4421DCB298F926DDB96BE0"}}
{"primaryAccession": "Q9P7R5", "text": "This is Gamma-tubulin complex component gfh1 protein, from Fission yeast, contains 577 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7R5", "organism_name": "Fission yeast", "protein_name": "Gamma-tubulin complex component gfh1", "length": 577, "firstPublicDate": "2009-02-10", "FUNCTION": "Required for proper anchoring of astral microtubules at the spindle pole bodies (SPBs), during anaphase, ensuring correct cell polarity", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TUBGCP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLHEIILLLAGNTSGLFIEKNGQILLHPSVQPLHPGERELINDIVSLASKRKRIERYIEIFDEDLIQQNQFLLKALRLLLSKKLFLYDESLANLERMIISSDPYFVGSGKFVSLAQLEAHLADWKETLSSLLVLQGNISQCLSVASTFQKLHNMYMGSTHLNFKKLVLECECAFQKTWLDELVQYLVNDSGDDSFKCSFLCGDTKDFVSCSNNVPFLTQDIVNCLVSIRTCMLNAKKCFTDAFCEILRCFYRLVYEMPLPLTKSSVTKLADEMFTLVSEKIIFQLASFHQIFDLVKMLEMVMLLENVEFLPTLSEMFRDVRGEYCSSNDVQGVVIDDILPVVLRKTISLLDLATEYGECVSFLKLVSIFDEEDEMIRSENRKIDVEGLNMQLLLCLKWPFNLFMDKNALNVYSDLWILLGSLHLSITKIKSLFYERKEYTAKGISQPWTQLWVTLWFLSSLQYYAYECVIKPSYCKLRESLTELYRTQKLRMQDCSQLHALTLTYAKKMLFFYDDDLHISLNSIYHELSLFRSQEVSKVDCQLAAHVSHSIECIRQKENDPSYDREIINALIVQLNL", "length": 577, "molWeight": 66765, "crc64": "206ECC12E9000303", "md5": "5F39E72479C035CB98F4835A79BC93A1"}}
{"primaryAccession": "Q9P7X0", "text": "This is Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial protein, from Fission yeast, contains 159 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7X0", "organism_name": "Fission yeast", "protein_name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "length": 159, "firstPublicDate": "2004-08-31", "FUNCTION": "Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the CybS family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLQTRLGLGALRQGRLLFAVKSFSTTSVAKIFPPPPQTIKGTVNDAAVFPHHSKLHGSYHWDFERIIAIAMVPQVMIPLFTGTSHPLMDAALACTLITHAHLGFESCVIDYFPARRFKKLSPLMHWILRGCTVLTLIGVYEFNTNDIGLTEGIKKLWKS", "length": 159, "molWeight": 17744, "crc64": "A4677656920A96C9", "md5": "2011E58DB8A99251E655AA8F0462CCDC"}}
{"primaryAccession": "Q9P8W0", "text": "This is Lipase 5 protein, from Yeast, contains 463 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P8W0", "organism_name": "Yeast", "protein_name": "Lipase 5", "length": 463, "firstPublicDate": "2003-11-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLYLILFLIAPIYAGLIFPTKPSSDPFYNPPKGFENAAVGDILQSRATPKSITGGFTPLKIQNSWQLLVRSEDSFGNPNVIVTTVIEPVNADPSKIASYQVFEDAAKADCAPSYALQFGSDLTTFVTQAEMYLMAPLLDQGYYVVSPDYEGPKSTFTIGKQSGQAVLNSIRAALKSGKITNIKDDAKVVMWGYSGGSLASGWAAALQPSYAPELGGNLLGAALGGFVTNITATAQATDGTVFAGIVANALGGVANEYPEFKSILQSDTDKKSVFDEFDGHCLIDGVLNYIGTSFLTGDHKIFKTGWDILKNPKIGKVVEDNGLVYQKQLVPKIPVFIYHGSIDQIVPIVDTKKTYQNWCDAGISSLEFAEDASNGHLTEAIMGAPAALTWIIDRFDGKQTVSGCQHIQRFSNLEYPNIPSSIANYFKAAMDVVLHLGLGPDVQKDQVSPEGIKKLGSIEMRWL", "length": 463, "molWeight": 49963, "crc64": "B1772055F5E7CD65", "md5": "7B55E2CD7703FEABD81F947A51925BF9"}}
{"primaryAccession": "Q9PT61", "text": "This is Homeobox protein otx5-B protein, from African clawed frog, contains 290 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9PT61", "organism_name": "African clawed frog", "protein_name": "Homeobox protein otx5-B", "length": 290, "firstPublicDate": "2007-04-03", "FUNCTION": "Transcription factor involved in anterior and eye development, Promotes the differentiation of both rod and cone photoreceptors cells in the retina, Together with other retinal homeobox proteins, acts as an effector of a cellular clock which, depending on cell cycle progression, establishes the generation of distinct retinal neuronal cell types, Acts synergistically with nrl to activate the rhodopsin promoter, Promotes the formation of anterior regions and represses the formation of posterior structures during development", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMSYIKQPHYAVNGLTLAGTGMDLLHSAVGYPTNPRKQRRERTTFTRAQLDILESLFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQSTGQAKPRPAKKKTSPARETNSEASTNGQYSPPPPGTAVTPSSSASATVSIWSPASISPIPDPLSAVTNPCMQRSTGYPMTYSQAPAYTQSYGGSSSYFTGLDCGSYLSPMHPQLSAPGATLSPIATPTMGSHLSQSPASLSAQGYGAASLGFTSVDCLDYKDQTASWKLNFNATDCLDYKDQSSWKFQVL", "length": 290, "molWeight": 31603, "crc64": "2277651FCCA03E7C", "md5": "D2B8E74283CEE00102EA5A6F1816090E"}}
{"primaryAccession": "Q9R1S3", "text": "This is GPI ethanolamine phosphate transferase 1 protein, from Mouse, contains 931 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9R1S3", "organism_name": "Mouse", "protein_name": "GPI ethanolamine phosphate transferase 1", "length": 931, "firstPublicDate": "2006-07-25", "FUNCTION": "Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis, Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor, May act as suppressor of replication stress and chromosome missegregation", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the PIGG/PIGN/PIGO family, PIGN subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLLFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIIHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIVSWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLIISDIMALHFFFLVKDSGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLQLCGKPKSHLM", "length": 931, "molWeight": 105045, "crc64": "75637C514E8D3AF4", "md5": "AE2820C7CEE110A6DF32FFA3AFCACDFD"}}
{"primaryAccession": "Q9S7B2", "text": "This is Protein rough sheath 2 protein, from Maize, contains 370 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9S7B2", "organism_name": "Maize", "protein_name": "Protein rough sheath 2", "length": 370, "firstPublicDate": "2007-08-21", "FUNCTION": "Transcription factor required for normal cell differentiation, Interacts directly with asymmetric leaves 2 (AS2) to repress the knox homeobox genes", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKERQRWRPEEDAVLRAYVRQYGPREWHLVSQRMNVALDRDAKSCLERWKNYLRPGIKKGSLTEEEQRLVIRLQAKHGNKWKKIAAEVPGRTAKRLGKWWEVFKEKQQRELRDSRRPPPEPSPDERGRYEWLLENFAEKLVGERPQQAAAAPSPLLMAAPVLPPWLSSNAGPAAAAAAAVAHPPPRPPSPSVTLSLASAAVAPGPPAPAPWMPDRAAADAAPYGFPSPSQHGGAAPPGMAVVDGQALAELAECCRELEEGRRAWAAHRREAAWRLKRVEQQLEMEREMRRREVWEEFEAKMRTMRLEQAAAAERVERDHREKVAELRRDAQVKEEKMAEQWAAKHARVAKFVEQMGGCSRSWSSATDMNC", "length": 370, "molWeight": 41919, "crc64": "B46825CA38003EE4", "md5": "362284A00E1EA263BC1F168263080388"}}
{"primaryAccession": "Q9SA49", "text": "This is Auxin-responsive protein SAUR41 protein, from Mouse-ear cress, contains 147 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SA49", "organism_name": "Mouse-ear cress", "protein_name": "Auxin-responsive protein SAUR41", "length": 147, "firstPublicDate": "2015-05-27", "FUNCTION": "Plays a role in the regulation of cell expansion, root meristem patterning and auxin transport", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ARG7 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKHLIRRLSRVADSSSEFSIRRSTSSFRNRRGHHRLHAPPPPWSICPARRVNTVPAGHVPVYVGEEMERFVVSAELMNHPIFVGLLNRSAQEYGYAQKGVLHIPCHVIVFERVVETLRLGGFEGSGDLENLVASLLSGDELIPETTE", "length": 147, "molWeight": 16479, "crc64": "A0BD859FDA8643AC", "md5": "3DEEF6DE0045596B4E4647E3F8601CE1"}}
{"primaryAccession": "Q9SCR0", "text": "This is Scarecrow-like protein 7 protein, from Mouse-ear cress, contains 542 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SCR0", "organism_name": "Mouse-ear cress", "protein_name": "Scarecrow-like protein 7", "length": 542, "firstPublicDate": "2008-09-23", "FUNCTION": "Probable transcription factor involved in plant development (Probable), Involved in environmental abiotic stress resistance, May increase the expression of stress-responsive genes (By similarity), Binds DNA in vitro (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the GRAS family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAYMCTDSGNLMAIAQQLIKQKQQQQSQHQQQEEQEQEPNPWPNPSFGFTLPGSGFSDPFQVTNDPGFHFPHLEHHQNAAVASEEFDSDEWMESLINGGDASQTNPDFPIYGHDPFVSFPSRLSAPSYLNRVNKDDSASQQLPPPPASTAIWSPSPPSPQHPPPPPPQPDFDLNQPIFKAIHDYARKPETKPDTLIRIKESVSESGDPIQRVGYYFAEALSHKETESPSSSSSSSLEDFILSYKTLNDACPYSKFAHLTANQAILEATNQSNNIHIVDFGIFQGIQWSALLQALATRSSGKPTRIRISGIPAPSLGDSPGPSLIATGNRLRDFAAILDLNFEFYPVLTPIQLLNGSSFRVDPDEVLVVNFMLELYKLLDETATTVGTALRLARSLNPRIVTLGEYEVSLNRVEFANRVKNSLRFYSAVFESLEPNLDRDSKERLRVERVLFGRRIMDLVRSDDDNNKPGTRFGLMEEKEQWRVLMEKAGFEPVKPSNYAVSQAKLLLWNYNYSTLYSLVESEPGFISLAWNNVPLLTVSSWR", "length": 542, "molWeight": 60779, "crc64": "77B213BB305D68E7", "md5": "85B24E24F34045B9015C41E37D9303BF"}}
{"primaryAccession": "Q9SGD6", "text": "This is Arogenate dehydratase/prephenate dehydratase 6, chloroplastic protein, from Mouse-ear cress, contains 413 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SGD6", "organism_name": "Mouse-ear cress", "protein_name": "Arogenate dehydratase/prephenate dehydratase 6, chloroplastic", "length": 413, "firstPublicDate": "2009-05-05", "FUNCTION": "Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine (PubMed:17726025), Dehydratase that uses arogenate and prephenate as substrates (PubMed:17726025), Utilzes more efficiently arogenate than prephenate (PubMed:17726025)", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKALSSSSPILGASQPATATALIARSGRSEWQSSCAILTSKVISQEESESLPVPPVSGGVDHLNGHNSAAARVPGMNLVPIEKSDSNPLVPQHRHNPLKPLSMTDLSPAPMHGSNLRVAYQGVPGAYSEAAAGKAYPNCQAIPCDQFEVAFQAVELWIADRAVLPVENSLGGSIHRNYDLLLRHRLHIVGEVQLPVHHCLLALPGVRKEFLTRVISHPQGLAQCEHTLTKLGLNVAREAVDDTAGAAEFIASNNLRDTAAIASARAAEIYGLEILEDGIQDDVSNVTRFVMLAREPIIPRTDRPFKTSIVFAHEKGTSVLFKVLSAFAFRDISLTKIESRPNHNRPIRVVDDANVGTAKHFEYMFYVDFEASMAEARAQNALAEVQEFTSFLRVLGSYPMDMTPWSPTSSTSS", "length": 413, "molWeight": 44802, "crc64": "70099DC47A932022", "md5": "6A57CD165F3617F703FF1B0F54B7E404"}}
{"primaryAccession": "Q9SHJ6", "text": "This is Peroxisomal and mitochondrial division factor 2 protein, from Mouse-ear cress, contains 323 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SHJ6", "organism_name": "Mouse-ear cress", "protein_name": "Peroxisomal and mitochondrial division factor 2", "length": 323, "firstPublicDate": "2015-04-29", "FUNCTION": "Involved in morphogenesis and proliferation of mitochondria, Does not act redundantly with PMD1, Is not involved in peroxisomal proliferation", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAEERSLNGEATGQDDESFFDSDQQGDDGKSTELNQKIGDLESQNQELARDNDAINRKIESLTAEIEELRGAESKAKRKMGEMEREIDKSDEERKVLEAIASRASELETEVARLQHELITARTEGEEATAEAEKLRSEISQKGGGIEELEKEVAGLRTVKEENEKRMKELESKLGALEVKELDEKNKKFRAEEEMREKIDNKEKEVHDLKEKIKSLESDVAKGKTELQKWITEKMVVEDSLKDSEKKVVALESEIVELQKQLDDAEKMINGLKNVVEEPLNGIEFKSWSPNVTAVGSGGAVAAVAVAVAGAAVVCYIYHSRRV", "length": 323, "molWeight": 36119, "crc64": "8E956C7B9985E077", "md5": "6DF4FA237BEC0D62F41322077A44427D"}}
{"primaryAccession": "Q9SJI7", "text": "This is Phospholipase A1-IIdelta protein, from Mouse-ear cress, contains 412 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SJI7", "organism_name": "Mouse-ear cress", "protein_name": "Phospholipase A1-IIdelta", "length": 412, "firstPublicDate": "2011-05-31", "FUNCTION": "Acylhydrolase that catalyzes the hydrolysis of phosphatidylcholine (PC) at the sn-1 position, High activity toward PC, medium activity toward monogalactosyldiacylglycerol (MGDG) and low activity toward triacylglycerol (TAG), Confers sensitivity to UV-B radiation probably by deesterifying membrane phospholipids", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATTTTSWEELLGSKNWDTILDPLDQSLRELILRCGDFCQATYDAFVNDQNSKYCGASRYGKSSFFDKVMLENASDYEVVNFLYATARVSLPEGLLLQSQSRDSWDRESNWFGYIAVTSDERSKALGRREIYIALRGTSRNYEWVNVLGARPTSADPLLHGPEQDGSGGVVEGTTFDSDSEDEEGCKVMLGWLTIYTSNHPESKFTKLSLRSQLLAKIKELLLKYKDEKPSIVLTGHSLGATEAVLAAYDIAENGSSDDVPVTAIVFGCPQVGNKEFRDEVMSHKNLKILHVRNTIDLLTRYPGGLLGYVDIGINFVIDTKKSPFLSDSRNPGDWHNLQAMLHVVAGWNGKKGEFKLMVKRSIALVNKSCEFLKAECLVPGSWWVEKNKGLIKNEDGEWVLAPVEEEPVPEF", "length": 412, "molWeight": 46057, "crc64": "4923CC470E4BEEF9", "md5": "7BACE1DCB1B9F3B73403F6930E87460B"}}
{"primaryAccession": "Q9SKZ5", "text": "This is Folate-biopterin transporter 1, chloroplastic protein, from Mouse-ear cress, contains 560 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SKZ5", "organism_name": "Mouse-ear cress", "protein_name": "Folate-biopterin transporter 1, chloroplastic", "length": 560, "firstPublicDate": "2012-10-31", "FUNCTION": "Mediates folate monoglutamate transport involved in tetrahydrofolate biosynthesis, It also mediates transport of antifolates, such as methotrexate and aminopterin", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the major facilitator superfamily, Folate-biopterin transporter (TC 2,A,71) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MASRSLFSISISPSQFTVLPSINNERRRLAIAARSHRLSRRKIRKRPPDRDMSSIVSIPELPRRRDSEESLLLDSRISVAEGDTSNTDVEGDRDTTSSIRTQPPPRKGRNLSSSRIKFYGVELSPDNVAVAMVYFVQGVLGLARLAVSFYLKDDLHLDPAETAVITGLSSLPWLVKPLYGFISDSVPLFGYRRRSYLVLSGLLGAFSWSLMAGFVDSKYSAAFCILLGSLSVAFSDVVVDSMVVERARGESQSVSGSLQSLCWGSSAFGGIVSSYFSGSLVESYGVRFVFGVTALLPLITSAVAVLVNEQRVVRPASGQKENITLLSPGFLQTSKQNMIQLWGAIKQPNVFLPTLFIFLWQATPHSDSAMFYFTTNKLGFTPEFLGRVKLVTSIASLLGVGLYNGFLKTVPLRKIFLVTTIFGTGLGMTQVILVSGFNRQLGISDEWFAIGDSLILTVLAQASFMPVLVLAARLCPEGMEATLFATLMSISNGGSVLGGLMGAGLTQAFGITRDSFGNLSTLIILCNLSSLLPLPLLGLLPRDSPDTLTKDDADVEMKSN", "length": 560, "molWeight": 60707, "crc64": "FE4DD6AFF6E97912", "md5": "395B592F87422E2656C253F01232FCC4"}}
{"primaryAccession": "Q9SQK3", "text": "This is Ankyrin repeat domain-containing protein EMB506, chloroplastic protein, from Mouse-ear cress, contains 315 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SQK3", "organism_name": "Mouse-ear cress", "protein_name": "Ankyrin repeat domain-containing protein EMB506, chloroplastic", "length": 315, "firstPublicDate": "2008-01-15", "FUNCTION": "Involved in the initial differentiation of the proplastid during the embryo development, Also required for correct cotyledon, true leaf and cauline leaf margin development", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVSSVLSIPPQTCLLPRLPISDSVNCKSKIVYCLSTSVRGSSVKRQSTARTRSFTETNRRTPSVQSKHEFWEDPDDGSDSENEYEGEEEDGIGNDLDNESDWEDDSRVQKLTTTDNYEEELAKEVEQLLEPEERVILQQNEKPNLKMISTKSWKPLQTLALSMQIQLMDNLIENGLDIDDVDKDNQTALHKAIIGKKEAVISHLLRKGANPHLQDRDGAAPIHYAVQVGALQTVKLLFKYNVDVNVADNEGWTPLHIAVQSRNRDITKILLTNGADKTRRTKDGKLALDLALCFGRDFKSYDLVKLLKIMPTGDI", "length": 315, "molWeight": 35461, "crc64": "B13F9C8D1850E714", "md5": "0F08CBBDE970DBDD83D191E1E341FBBF"}}
{"primaryAccession": "Q9ST69", "text": "This is Small ribosomal subunit protein uS5c protein, from Spinach, contains 308 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ST69", "organism_name": "Spinach", "protein_name": "Small ribosomal subunit protein uS5c", "length": 308, "firstPublicDate": "2006-09-05", "FUNCTION": "Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the universal ribosomal protein uS5 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATTATTTPSATSLTTLHRRIPLFPTTTTLLSLSSSSKPLFLSLSSTRSFPTHLYCIKKDDIDITFFEQDNPDEEITFDPPEKPEGYIPPRAVDEPPFESEEEIALAYEELYGAAYSGESLLGNDVYAMDSKIKKATGFGSKSKKEKIRDGFEENVVQVRRVTKVVKGGKHMRFRAIVVVGDKKGQVGVGVGKAKEVVSAVQKAAVDARRNIITVPMTKYLTFPHRNEADYGAARVMLRPAAPGTGVIAGGAVRTVLEMAGVENALGKQLGSNNALNNARATIVAVQTMRQFSDVARDRGIPMEELWK", "length": 308, "molWeight": 33581, "crc64": "EE8E29B8D43E1CB1", "md5": "E2108BC5A2E763C579EFE8FCC4F773D7"}}
{"primaryAccession": "Q9STX1", "text": "This is Acyl-CoA-binding domain-containing protein 3 protein, from Mouse-ear cress, contains 362 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9STX1", "organism_name": "Mouse-ear cress", "protein_name": "Acyl-CoA-binding domain-containing protein 3", "length": 362, "firstPublicDate": "2009-07-28", "FUNCTION": "Binds medium- and long-chain acyl-CoA esters with very high affinity, Can interact in vitro with arachidonyl-CoA, barely with oleoyl-CoA, but not with palmitoyl-CoA", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the ACBP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEVFLEMLLTAVVALLFSFLLAKLVSVATVENDLSSDQPLKPEIGVGVTEDVRFGMKMDARVLESQRNFQVVDENVELVDRFLSEEADRVYEVDEAVTGNAKICGDREAESSAAASSENYVIAEEVILVRGQDEQSDSAEAESISSVSPENVVAEEIKSQGQEEVTELGRSGCVENEESGGDVLVAESEEVRVEKSSNMVEESDAEAENEEKTELTIEEDDDWEGIERSELEKAFAAAVNLLEESGKAEEIGAEAKMELFGLHKIATEGSCREAQPMAVMISARAKWNAWQKLGNMSQEEAMEQYLALVSKEIPGLTKAGHTVGKMSEMETSVGLPPNSGSLEDPTNLVTTGVDESSKNGIP", "length": 362, "molWeight": 39267, "crc64": "62432733AC52DE14", "md5": "D823524D9E25F2B9F28FE77A267924AA"}}
{"primaryAccession": "Q9SU50", "text": "This is Trehalase protein, from Mouse-ear cress, contains 626 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SU50", "organism_name": "Mouse-ear cress", "protein_name": "Trehalase", "length": 626, "firstPublicDate": "2012-06-13", "FUNCTION": "Involved in the regulation of trehalose content by hydrolyzing trehalose to glucose", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the glycosyl hydrolase 37 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKSYKLNNPNLLISTHTHNKLFLSSSPFNLLFSFPSFIYLKQQRSLFFFFFFFLCFSFTTSMLDSDTDTDSGPVVATTKLVTFLQRVQHTALRSYPKKQTPDPKSYIDLSLKRPYSLSTIESAFDDLTSESHDQPVPVETLEKFVKEYFDGAGEDLLHHEPVDFVSDPSGFLSNVENEEVREWAREVHGLWRNLSCRVSDSVRESADRHTLLPLPEPVIIPGSRFREVYYWDSYWVIKGLMTSQMFTTAKGLVTNLMSLVETYGYALNGARAYYTNRSQPPLLSSMVYEIYNVTKDEELVRKAIPLLLKEYEFWNSGKHKVVIRDANGYDHVLSRYYAMWNKPRPESSVFDEESASGFSTMLEKQRFHRDIATAAESGCDFSTRWMRDPPNFTTMATTSVVPVDLNVFLLKMELDIAFMMKVSGDQNGSDRFVKASKAREKAFQTVFWNEKAGQWLDYWLSSSGEESETWKAENQNTNVFASNFAPIWINSINSDENLVKKVVTALKNSGLIAPAGILTSLTNSGQQWDSPNGWAPQQEMIVTGLGRSSVKEAKEMAEDIARRWIKSNYLVYKKSGTIHEKLKVTELGEYGGGGEYMPQTGFGWSNGVILAFLEEYGWPSHLSIEA", "length": 626, "molWeight": 71355, "crc64": "A23D8E2C9C2D048F", "md5": "6DA994471A1BCAB7F30BEF48652D5769"}}
{"primaryAccession": "Q9SU91", "text": "This is Probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, mitochondrial protein, from Mouse-ear cress, contains 336 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SU91", "organism_name": "Mouse-ear cress", "protein_name": "Probable acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, mitochondrial", "length": 336, "firstPublicDate": "2013-03-06", "FUNCTION": "Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell, Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the transferase hexapeptide repeat family, LpxA subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MISLLKAREKLLSPLVSSTIRRLSSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFRQWLDSTT", "length": 336, "molWeight": 36714, "crc64": "D51A40A3FAED226A", "md5": "B00F11DF60E7170533A508EBDDAF9438"}}
{"primaryAccession": "Q9SX65", "text": "This is 1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1 protein, from Mouse-ear cress, contains 156 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SX65", "organism_name": "Mouse-ear cress", "protein_name": "1,4-dihydroxy-2-naphthoyl-CoA thioesterase 1", "length": 156, "firstPublicDate": "2015-03-04", "FUNCTION": "Catalyzes the hydrolysis of the thioester bond of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) in peroxisomes, a necessary step to form the naphthoquinone ring of phylloquinone (vitamin K(1)), Is not active on benzoyl-CoA, phenylacetyl-CoA, succinyl-CoA and palmitoyl-CoA thioesters", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the 4-hydroxybenzoyl-CoA thioesterase family, DHNA-CoA hydrolase subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDSASSNTKAIDPPLHMLGFEFDELSPTRITGRLPVSPVCCQPFKVLHGGVSALIAESLASMGAHMASGFKRVAGIQLSINHLKSADLGDLVFAEATPVSTGKTIQVWEVKLWKTTQKDKANKILISSSRVTLICNLPIPDNAKDAANMLKMVAKL", "length": 156, "molWeight": 16713, "crc64": "986C79FC0F985B23", "md5": "1074A52A7EF22245988404903E327D15"}}
{"primaryAccession": "Q9TUQ3", "text": "This is Complement component C7 protein, from Pig, contains 843 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9TUQ3", "organism_name": "Pig", "protein_name": "Complement component C7", "length": 843, "firstPublicDate": "2002-09-19", "FUNCTION": "Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells, C7 serves as a membrane anchor", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the complement C6/C7/C8/C9 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKAMSLVFLVGLIGEFQVFSSASSPVNCQWDSYAPWSECNGCTKTQTRRRPVAVYGQYGGHPCVGSTFETQSCEPTRGCPTEEGCGERFRCFSGQCISKSLVCNGDSDCEEDSADEDRCEDSESRPSCDLSKPPPNIELTGNGYNALTGQFRNRVLNTKSFGGQCRKVFSGDGRDFYRLSGNVLSYTFQVKVNNDFNYEFYNSTWSYAKHTSTEHTSSSKGRVFIFSSSSSSSSYYAKTYEILKKKSYQLLVVQNTVEVAQFINNNPEFLQLAESFWKELSYLPPLYDYSAYRRLIDQYGTHYLQSGSLGGEYKVLFYVDSEKVAESDLGSEDKKKCASSHISFLFKSSKHKCKAMEEALKSASGTQSNVLRGVPFVRGGRPGFVSGLSYLELDNPDGNKQRYSSWAGSVTDLPQVIKQKLTPLYELVKEVPCASVKRLYLKRALEEYLDEFDSCHCQPCQNGGMASVEGTQCQCHCKPNTFGVACEQGVLVGDHAGGIDGGWSCWSSWGPCAQGKKTRSRKCNNPPPSGGGKSCIGETSESRQCEDEDLEHLRLLEPHCFPLSLVPTEFCPSPPALKDGFVQNEETTFPVGKNIVYSCNEGYSLVGDPVARCGEDLQWTVGKMHCQKIACVLPTLMRGLQSHPQKPFYTVGEKVTFSCSSGMSLEGPSTFLCGSSLKWSPEMKNVQCVRKEAPLAKKVPECQLWEKLQNSKCVCKMPYECGSSLDVCARDERSKRILRLTVCKMHVLQCQGRNYTLSVGETCTLPGSAEKACGACPLWEKCDAQSSKCVCRAASECEEAGFRVCVEVNGREQTMTECEAGVLRCLGLSITVTSIRPCAPEAP", "length": 843, "molWeight": 93062, "crc64": "0B703D93C3E5C83D", "md5": "4E81FFBEFDF9194F73C5F65FC08C7A91"}}
{"primaryAccession": "Q9TXD8", "text": "This is Venom peptide isomerase heavy chain protein, from North American funnel-web spider, contains 243 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9TXD8", "organism_name": "North American funnel-web spider", "protein_name": "Venom peptide isomerase heavy chain", "length": 243, "firstPublicDate": "2011-02-08", "FUNCTION": "Peptide isomerase that inverts the chirality at the Ser-81 of omega-Aga IVB, Acts cofactor-independently", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "IVGGKTAKFGDYPWMVSIQQKNKKGTFDHICGGAIINVNWILTAAHCFDQPIVKSDYRAYVGLRSILHTKENTVQRLELSKIVLHPGYKPKKDPDDIALIKVAKPIVIGNYANGICVPKGVTNPEGNATVIGWGKISSGGKQVNTLQEVTIPIIPWKKCKEIYGDEFSEFEYSQITPYMICAGAEGKDSCQADSGGPLFQIDANGVATLIGTVANGADCGYKHYPGVYMKVSSYTNWMSKNMV", "length": 243, "molWeight": 26511, "crc64": "582EC10BEAA058E2", "md5": "CB51A81E2DEB695EAEC68C975B5F9EE0"}}
{"primaryAccession": "Q9UHA3", "text": "This is Probable ribosome biogenesis protein RLP24 protein, from Human, contains 163 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UHA3", "organism_name": "Human", "protein_name": "Probable ribosome biogenesis protein RLP24", "length": 163, "firstPublicDate": "2004-09-27", "FUNCTION": "Involved in the biogenesis of the 60S ribosomal subunit, Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eL24 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRIEKCYFCSGPIYPGHGMMFVRNDCKVFRFCKSKCHKNFKKKRNPRKVRWTKAFRKAAGKELTVDNSFEFEKRRNEPIKYQRELWNKTIDAMKRVEEIKQKRQAKFIMNRLKKNKELQKVQDIKEVKQNIHLIRAPLAGKGKQLEEKMVQQLQEDVDMEDAP", "length": 163, "molWeight": 19621, "crc64": "1E5D9ECFFCF678D1", "md5": "F8FFA2805A944D83412C0E115ABE3F3F"}}
{"primaryAccession": "Q9USP9", "text": "This is Uncharacterized RNA-binding protein C902.04 protein, from Fission yeast, contains 589 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9USP9", "organism_name": "Fission yeast", "protein_name": "Uncharacterized RNA-binding protein C902.04", "length": 589, "firstPublicDate": "2004-03-29", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPLFLEEHAEYLKRYLEQALEPISDADASVLSDYAMALLRHDSSEEEVRQLCYSQLEDFLRQETIPFVDKIFDVLREKSYLEGASNMPSTGMVTEEVSRYSPTSSMIPATNSMETNFNNSLPAVGKTNTFPSQVPNMFGPPLYHPAATAPSEFMPSIPGFGNLPNPAMPPIPFLPFNPAAQPPFPPPFKMRGKRGFGMRHEHNSELRRHSPGNRRFNPYKAYPQPHLGHRFSRNAGNDPTSTALEVRNIPEEHFNEENIRSFFSKFGVLEKVELNPTHHSCVLEFTSHEAANNAWSSPEPIFNNRFIKIFWYNPSKGFHNRPKKFASHKSPTTSDSSNVESSEDVDPASLLQNEEFHKLIEERQRQHEERLKRINANKKALEELNQKKRELAQQQLKEQELLMQKIKETDRSGNKRLMLLETQHSLLKAEADCLGLPVSNVSESPAASNGSHHPYASGLPQRGTNTFFRGRGRGRGDMFASMSIDNRPTKLRVINVSPEKNEALLQYLFTVGGYEEITEPSTTERLISFQNRNSAEKFFGGVRNVEKLQELELAWVPKTAVTTNTTSMETGESNTSDNMNIEVEEGRWR", "length": 589, "molWeight": 66899, "crc64": "6012DBEF0C6162CA", "md5": "E0B8C0DFA70A8C54556AF25B5571CDA1"}}
{"primaryAccession": "Q9USU8", "text": "This is Chromatin-remodeling complexes subunit ngg1 protein, from Fission yeast, contains 551 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9USU8", "organism_name": "Fission yeast", "protein_name": "Chromatin-remodeling complexes subunit ngg1", "length": 551, "firstPublicDate": "2008-11-04", "FUNCTION": "Transcription regulator, Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA, SLIK and ADA, SAGA is involved in RNA polymerase II-dependent transcriptional regulation of a subset of genes, At the promoters, SAGA is required for recruitment of the basal transcription machinery, It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination, SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac), SAGA interacts with DNA via upstream activating sequences (UASs), SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation, SLIK is proposed to have partly overlapping functions with SAGA, It preferentially acetylates methylated histone H3, ADA preferentially acetylates nucleosomal histones H3 (at 'Lys-14' and 'Lys-18') and H2B", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the NGG1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSEQQNEADSKPAVIPQCFKIENQYETFSRLSETSTPGVVPSVSTLWRLLFELQKMIECEPSCVEYFRQRKEELESHVDSEIETSKDESSVNKVEEKVEEFKEDNVEQEIKQKRSLSESPQESMLEKVSKKPKVSEAHNEEISPENVETIENELDLPVKGKDEQTTGLVYKNANDLLTGSLLSFIVDDSFSYEQKKKLLCVDSFPTSDVRSLVAGTPATDDFSHNKPNNQISISTFYSSLDPYFRAFNDDDIAFLKKGFDVSSSYNIPPLGERYYDLTPEDEMTNLCANSIYQNLQTSAQGSLEAFNEADTVSEEVRCGPLTERLMASLIPCYTQNDEEQKPSIAVGEFAETDSGSEKSKIGTSIDGIESGNNEYTEQPDIQESSLSICEDRLRYTLKQLGILYDGDVDWSKRQDDEISATLRSLNARLKVVSDENEKMRNALLQMLPEEMAFQEFQNVMDDLDKQIEQAYVKRNRSLKVKKKRIVTDKIGSSATSGSFPVIKSLMDKRSMWLEKLQPLFQDKLTQHLGSPTSIFNDLSDHTTSNYSTSV", "length": 551, "molWeight": 62407, "crc64": "F037D741B0A78403", "md5": "4DD0585BD3D5402EC28004A85E1C4193"}}
{"primaryAccession": "Q9USY1", "text": "This is Pseudouridine-metabolizing bifunctional protein C1861.05 protein, from Fission yeast, contains 747 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9USY1", "organism_name": "Fission yeast", "protein_name": "Pseudouridine-metabolizing bifunctional protein C1861.05", "length": 747, "firstPublicDate": "2009-02-10", "FUNCTION": "Bifunctional enzyme that catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP), and the reversible cleavage of pseudouridine 5'-phosphate to ribose 5-phosphate and uracil, Is involved in a pseudouridine degradation pathway", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "In the C-terminal section; belongs to the carbohydrate kinase PfkB family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLIVMNRGCRLVSRIPLGFRRLKRNPNPGLRNILCRRYSPLALSKEVTEALKNNVPVVALESTIITHGMPYPQNEELAIQVESKVRSMGAVPATIALLNGQCTIGLEQFQLSELAKSGETAYKVSRRDLSYVASQRLNGGTTVAATMILARAAGIDVFATGGIGGVHRGAENSMDISADLIELGRTRVAVVSAGVKSILDIGRTLEVLETQGVPVVTLGPPKSAFPAFFSRESKFQSPLSLETPQLIANMLFSNIQLGQECGTLVAIPTPHHCSIDYEKMEALIETCLQRSVQLGITGKNVTPWLLGELLRESKGKSLNTNIDLVLNNAEKASLIAKELAVLKEKSSFFPTNTGNTFETKPVKQDFFYGKVSDKGVSSSKKKITETTSKPAEVVCVGSVSIDSVLKLDNPLTSKFLGTSHPCHSEQAFGGVAHNMALASSLMGASTKLVSCVGTKSVPTSSIKEYLTKSSLQHTIVEKSNFTSCSYTAINDCNGNLLLAGADMAIMENLSYSEIKDDLNDAKYICFDGNISPSLMLDITTSKSSKQRVVFEPTSGPKTLKILKVLSVASIDFITPNKFELDVLFQAMKDGNFFENESWWQKLNSFGITSSFYNEIERFTKSTGIEEITENGILQKCFHLLPFIKNIIVKLGPNGALLISSEKLQGVNSNSASLFTPGNVTVKYYPVPKVIATPVNASGTGDTFIGTFTALLSKGWGMDDAIDTAQKAAGLTLQCNFSVNPEIKTLLK", "length": 747, "molWeight": 80759, "crc64": "6AD61E36FE7D9420", "md5": "48124061040F6484C6111E2FFC7B3A63"}}
{"primaryAccession": "Q9UT52", "text": "This is Gamma-tubulin complex subunit mod21 protein, from Fission yeast, contains 677 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UT52", "organism_name": "Fission yeast", "protein_name": "Gamma-tubulin complex subunit mod21", "length": 677, "firstPublicDate": "2008-11-04", "FUNCTION": "Component of the gamma-tubulin complex that is required for the regulation of both interphase microtubule organization and nucleation, and mitotic bipolar spindles, Required for correct septation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTMSRADQILQHLLRELIHNDSLVASEWLKHSKKIIQNVPSSTLVFHEMIEHIKGICDKMGIQGREDLEMPLRNACEVLNRQTVSVKQSILHAQILKLFLELSKPPSDIHVPQIPVYKDCNKNEQEAIIQLLTSCEGDHWLMPDWSSMPDDETITEDSEEETFNGNANEITIPANIHIPIIEESDNASNNKLCTLFKKSKQPNLDFLQIKPFMFWDSSLNETVRISERSIIRDSIYMLIGYPSFFFLKNGSKIETRLSLLPKLHHMSEEILRSIMTELADYGSNLEFFRQKLTSPSDSFFKSDDQSTKNEPFLSVVFIYPQIKPHLLSCLKNTHQELIKLETEVYNATKNCTLFQFFQHVKKFVDPLLCFRFAYEKSATNMWDFVKTLEFIYSTRNYSSQMFKLYKASAIAMLLWMVNQASQITSSMTIARPLYNILILCKDFPNNFLEKDNIALQLGSIVFDQSPTLNNLLVEMEILIRSKILKLGKSLDLSFDFQSLMGEFENLIKQQEEAKKSLWSKRFSRFYYGHYVFVNTCHNFFLTLYQSFTEVDENSIFNGVFETLNNDVDDESVIGEKEKLILKQKQKCLSEFFVDDIKKLLNEELLNCQKQELPDVMENTYQISTVSGIKNDPLFTLDQTCNIIAKLADNLIHPSVPIGSSAYRCRRNLADLLFLIMP", "length": 677, "molWeight": 78427, "crc64": "5BDFF0AFCAF2E24D", "md5": "5800378AD48A1C140647E9D869007547"}}
{"primaryAccession": "Q9UU83", "text": "This is Protein pal1 protein, from Fission yeast, contains 425 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UU83", "organism_name": "Fission yeast", "protein_name": "Protein pal1", "length": 425, "firstPublicDate": "2005-05-10", "FUNCTION": "Involved in cellular morphogenesis and cell wall integrity, Important for the maintenance of a cylindrical cell shape", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the pal1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MMVIENPFLSTATSSQTPQEDGVYTSSLHNSNNPFLAPKTERVADPVMESMADDLFNSIQKKKEPSPASSASASPVKKSAEALAERSNSSMGTFDPPPRYSKIARARSTHVASSSRHRSPSHNDSSPSTQSSLKSRGSIRRYKSVREGSHRPGRSSKEPLDQIDRLDVTGLYGSGSFHHDGPFDACRPHRNRNSKKAPVAAFPKDSIANSIPKVGETYNDPSVPKDFSRKAIHESLRTKNILQSPYKSVGIEEEFPSSGNNDTPGLTDSTRIEGAMASKNAIARNEEMLAMEKAGLGRKNSLIRKLGLNRSASMMSRTPNTLNRPSNYRSHSSMGTRRSPLNSPSQLDPISNENESDTDDSNTGLRNRTSPTAAPPPPSRRKTGGLNTRPYPQHAESQMSLPLTAKERSKPKKMGFFRRLFHKKS", "length": 425, "molWeight": 46629, "crc64": "A298ED69F4FE0FA7", "md5": "17243EA5B9A6F207A8C2F837790E226D"}}
{"primaryAccession": "Q9VDH4", "text": "This is Protein Turandot B protein, from Fruit fly, contains 138 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VDH4", "organism_name": "Fruit fly", "protein_name": "Protein Turandot B", "length": 138, "firstPublicDate": "2008-11-25", "FUNCTION": "A humoral factor that may play a role in stress tolerance", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the Turandot family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNFKTSLICFALLLIGTLCSAYSNQERQRDSRRVAEIMRTSWDDNTKIKRIQELLTIYNRMAPSLRPDERARMDRFISGYTGEIMVDGVPSQGGARRIFKKILSPAAKSVATGFFTELGASLASILTSWFPANTERNH", "length": 138, "molWeight": 15594, "crc64": "1762A36B67581092", "md5": "6DC978000267B537129120203DECB669"}}
{"primaryAccession": "Q9VE04", "text": "This is Large ribosomal subunit protein mL55 protein, from Fruit fly, contains 107 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VE04", "organism_name": "Fruit fly", "protein_name": "Large ribosomal subunit protein mL55", "length": 107, "firstPublicDate": "2007-01-23", "FUNCTION": "Involved in mitochondrial biogenesis and G2/M phase cell cycle progression", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mL55 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLLKQLPQAVQQIRCISSATTAVTRLHRSVYCRLYPTVVVQPDGSTINIRYHEPRKIIKLPLDLSTLTDAERRARLEARKPRKKVKIMEEVEDNFNAKKYMKYIKKK", "length": 107, "molWeight": 12568, "crc64": "6E93D5DE48BCB853", "md5": "00BB3FAB01E4702D9BF7E92C8C69696A"}}
{"primaryAccession": "Q9VH70", "text": "This is Testis-specific zinc finger protein topi protein, from Fruit fly, contains 814 amino acids, has 10 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [228, 250], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [275, 297], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [360, 382], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [429, 453], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [467, 490], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [511, 533], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [539, 564], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [570, 592], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [598, 620], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [626, 649], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9VH70", "organism_name": "Fruit fly", "protein_name": "Testis-specific zinc finger protein topi", "length": 814, "firstPublicDate": "2003-09-26", "FUNCTION": "Required for male meiotic division and spermatid differentiation, Required for accumulation of aly and comr on chromatin, May function as a transcription factor", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 10}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKVKVSGEYTLAEIEVELDQQLTPDDLQPGATVLATNESTGGLERIVSHEELSRFFAVGPAGALPMPTDVVVERTLADPAFKQILQEADGKKGFDPQAEQMKIRDFLAGVTSSKMTTEQSVFHGSRSNSSASTVNRIKCPTCLVQFDAVAFQNHSCEAKPIEVAVPQQEKPHLVPTVSAPPAPLSKPASERVIRENQVRLRRYIKDEMKYDLATGIESSRKNAAKGPNECTMCDRKFVHASGLVRHMEKHALDLIPSQTSEQPHTIPAAGLHVVVKCNSCGRIFYDPQVAFRHGLIHDSEHSTMRQSPMTQVPSNRADFNELLLDGEMLIDNDPAFATSNQNTNPPKKEMFSSLILGSVLQCEFCEYIFADIAELLVHSASHVAERRFECTACDIQMNTAKEASIHFQTDCIFMREAIRSLNVTLSRYFVCNVCELKFANTDLLQEHRCTSFHYFPRLNENGKKLLLPCDFCDVNFEFAHDFLAHSEEKHLNKKKREKETRNTGAGRIRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFVCQEENCDRKFTIRPDLNDHIRKCHTGERPYLCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPYSCLFCTKTFRQRGDRDKHIRARHSHLDANSRLMMQMQKFQLETAAAQKAQSHNPEQQDNDVAGGASTSDVPSGSGFMSTEPSVAEMQYSITPEQQEEMVCVPIDEVNNSFFMSHYMQAVPMEEDGSGQHIIVFEQPGQNMDMMSIYDQQQVGEPMHESGVPKRPAEENARVVVVKNNPTKPIFSDTYL", "length": 814, "molWeight": 92206, "crc64": "39C63AF193ED7806", "md5": "7E87D67423857CAE07818A4069D0E2C6"}}
{"primaryAccession": "Q9VKQ9", "text": "This is Protein dpy-30 homolog protein, from Fruit fly, contains 134 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VKQ9", "organism_name": "Fruit fly", "protein_name": "Protein dpy-30 homolog", "length": 134, "firstPublicDate": "2014-06-11", "FUNCTION": "Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and of the MLL3/4 complex which also methylates histone H3 'Lys-4', Inhibits MTF-1 transcription factor activity", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the dpy-30 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEAKTDAPISPAPTTNPPAEAGKEPNASSNAQANPTAAPGAPPSGAIAVGQSTNPVAQQQQQPAVAKKPSSETNNMPTRQYLDQTVAPVLLHGMQALARERPTDPIQFLASYLLKHSNGCDENNASAAAVDNNS", "length": 134, "molWeight": 13794, "crc64": "0A9E18CA132E9A57", "md5": "284A8FD69CE217C7DEFD9BB694973FAF"}}
{"primaryAccession": "Q9VM91", "text": "This is Tubulin glycylase 3A protein, from Fruit fly, contains 992 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VM91", "organism_name": "Fruit fly", "protein_name": "Tubulin glycylase 3A", "length": 992, "firstPublicDate": "2009-09-01", "FUNCTION": "Polylycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin, Involved both in the side-chain initiation and elongation steps of the polyglycylation reaction by adding a single glycine chain to generate monoglycine side chains and by elongating monoglycine side chains to polyglycine side chains", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQTRPSSEPHRSRDQVTDGDRNRDQPQKCASATLAKKPVTPPAAPPPTPSNRVVAPLTVPVIQLTPAQSDSPVKLARPATPKETAISVPDHSNKENQPARTPPPSKSCPLGAPTNYVARRTWITTERMNELRRKAQEAAKQNKIFTIRGCFNSVRNALLMRGWVEKLDVHRKVMPAGQMTYEDLTQRLPKRKAGETRRQYVQKCERNIMSRFLEHMPVDFLWTNRKEKCDYIDQAKNPGMTINKFHRAPFTSKEGLCSQLRDFHWFFEEGTAEMYFPRCYNVWSPEELGEFIENFKLTACVAFLRAMLCKYHKQGSDAVFSCSGKIPYSAIDFAYKRLVEYIDSCQHNDIDFEDPPKIWEHDWDAFLFQHQQLVNEDGRIQHDGGQRLEPMVKSCLSLVDKMKVHWPQYSLDGYQNMWIVKPANKCRGRGIILMDNLKKILGVVNLSIASKSRYVVQKYIERPLILFQTKFDIRQWFLITNTQPLVVWFYRESYLRFSSQEYSLSNHHESVHLTNYAIQKKYTNGKRDKRLPSENMWDCYSFQAYLRQIGKYNMWLERIFPGMRKAIVGCMLASQENMDRRPNTFELFGADFMICENFYPWLIEINSSPDLGATTSVTARMCPQCLEDVVKVVIDRRTDPKAELGNFELAYRQVVPPTPAYMGLNLFVKGKQVLQKANHGGGHGHYYYQQQRKERSLATSSVYRQRSAIIHPATSISRIHRAMPTFNATEYMEKYMVEPLSSSRSSLCSQLPQKSPSAAPALTATPSGATSSYILKQAGRSITQLLSATHKRNTGGSLSGEQVQSTALPPKRQRSCGPRLSSTNPVESTEKKFKILIKNYSSNGNENMQDARPEVANSATATAISERKWRSLRNIAATAGGSSNLAARSKGPPLIAPPSLPTRRLTRTKSEIDSTGMHAIGRTFGRKSNGPRLPISISVQALHRGEPIVAALKQATSELQLSQAQMMSPRTALANKLNGSTLMVPASALPVG", "length": 992, "molWeight": 112256, "crc64": "0FC34674C15BDAAD", "md5": "27170FD71A9AE290B2BD65DB8B3BE79F"}}
{"primaryAccession": "Q9VSK8", "text": "This is Zinc finger CCCH domain-containing protein 3 protein, from Fruit fly, contains 597 amino acids, has 3 C3H1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [397, 423], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [424, 450], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [451, 478], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9VSK8", "organism_name": "Fruit fly", "protein_name": "Zinc finger CCCH domain-containing protein 3", "length": 597, "firstPublicDate": "2015-10-14", "FUNCTION": "Required for the export of polyadenylated mRNAs from the nucleu; binds to polyadenylated mRNA, and is involved in the regulation of mRNA polyadenylation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C3H1-type Zinc finger": 3}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLPHISADEAQPSMSRKVYINPNFQLQGQTAHQLPFQVPFQAFQAPLQPQPAIHINPHFLNRQRAMYDQYQREQQEQLMMQQVSASHYRLDPTIHLLATPPPPPAKIISKVSTCLVRKPSVVASGPAVKLAASVPVPTVSSLVQPPLVSISKRKIVRQGALKAAPAVAALHPPPPAKRTRYKLVRSISLTCTPLVKKRRPLREFVGQYALRRTNEAQPNRKLSSKPQALKLGVNKSLSMVSIHGVMYKKISKNKITKLDASSSARVAKSESPRTLQRTLSGRTLFVSGNKFILDPSGCRLTRVSTSSTGATQSSVNRSILRRIDIGGLTYVASPKALNVFVRTSNHVSRAHLITAKQRSLTLLNKSLVKTNVPCAIFQKLGKCVAHSRGKCRKLHDKRQVAICVSFLRGECTKPKCLLSHNVTLEKMPVCRYYLRGVCVREDCPYLHKKLSSKTEICIDFVRGYCPLAAECNKRHEFSCPELERKGKCELPRCVFCKKSPSKRLAKVKSRPKLGSKPVAFTDTAKESSTADELPTSSRYFGSHKEPAEAILTRDDVEQKKPEAEDEDQKEAGAPCPRRRPQLGTLPSFIPLGGEEKL", "length": 597, "molWeight": 66322, "crc64": "A2D190600601BC22", "md5": "3BBBE5BD60F81C8842D79D639C9632E1"}}
{"primaryAccession": "Q9W701", "text": "This is Chloride channel protein ClC-Kb protein, from African clawed frog, contains 689 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9W701", "organism_name": "African clawed frog", "protein_name": "Chloride channel protein ClC-Kb", "length": 689, "firstPublicDate": "2010-02-09", "FUNCTION": "Voltage-gated chloride channel, Chloride channels have several functions including the regulation of cell volume, the stabilization of membrane potential, signal transduction and transepithelial transport", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the chloride channel (TC 2,A,49) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSRVLVIEQREGEEKTLIQKHIFRPFPNTRRVVIDHLQRLKNFLFRIGDDWYFLFALGVIMALISFTMDFTVSKMLNAHRWLQQELGGNVLLRYLSWIVYPIALVAFSTGFAQSITPHSGGSGIPELKTILSGVILEEYLTIKNFGAKVVGLTCTLSAGSTMFLGKVGPFVHLSSMIAAYLGRMRTSVAGDYENKSKEHEMLVAAAAVGVSTVFGAPISGVLFSVEVMSSHFAIRNYWRGFFAATCGAFVFRLLAVFNSEQETITAVFKTSFKISFPFDLPEMFFFAILGVVCGLIGCAYLFCQRWLLGYVRRNSLTSKLLASDKPMYSALVALLISSITFPESLGQFLASRLTMKELLTSLFDNRTWWISLSQNSSLDRSPLVDPNNLWLEWANPQFTIFGTLAFFIIMKFWMFILATTLPMPAGYFMPVFVFGAAIGRLVGETVALLYPEGIAADGIVNPIIPGGYAWQGAPAYSGAVTHSVSTALLAFEATGQIAHILPVILCVLIANAFTQKLQPSFYDGTIIVKKLPYLPRIRSRDIDSYKVNTEEFMNPDIRVLPREAGFEDVLKVITASDDSEYPVVDNTESQVLVGTVKRPQLIHFLETHESHERAGPTEKENLSEGNLGEACSIEPVTFQLSTWTSLHQAHHLFELLHLQKAFVTKYGRIVGQVTRKEMKKAIEDLANPK", "length": 689, "molWeight": 76800, "crc64": "4C0E95DDF4DC495F", "md5": "3C51B5245ECB45C51B69AB2A8207A9C5"}}
{"primaryAccession": "Q9XI36", "text": "This is Methyl-CpG-binding domain-containing protein 10 protein, from Mouse-ear cress, contains 384 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XI36", "organism_name": "Mouse-ear cress", "protein_name": "Methyl-CpG-binding domain-containing protein 10", "length": 384, "firstPublicDate": "2011-03-08", "FUNCTION": "Probable transcriptional regulator (By similarity), Required for nucleolar dominance that consist in the silencing of rRNA genes inherited from one progenitor in genetic hybrids", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MENTDELVSIELPAPASWKKLFYPKRAGTPRKTEIVFVAPTGEEISSRKQLEQYLKAHPGNPVISEFEWTTGETPRRSSRISQKVKATTPTPDKEPLLKKRRSSLTKKDNKEAAEKNEEAAVKENMDVDKDGKTENAEAEKEKEKEGVTEIAEAEKENNEGEKTEAEKVNKEGEKTEAGKEGQTEIAEAEKEKEGEKAEAENKEAEVVRDKKESMEVDTSELEKKAGSGEGAEEPSKVEGLKDTEMKEAQEVVTEADVEKKPAEEKTENKGSVTTEANGEQNVTLGEPNLDADAEADKGKESKEYDEKTTEAEANKENDTQESDEKKTEAAANKENETQESDVKKTEAAVAEEKSNDMKAEDTNRSLEANQVQQQQGAAASVSC", "length": 384, "molWeight": 42358, "crc64": "29CA77B564341023", "md5": "A1AE8225C019E55165EAC11EAA45AEDC"}}
{"primaryAccession": "Q9XVW1", "text": "This is Regulator of hypoxia-inducible factor 1 protein, from Caenorhabditis elegans, contains 502 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XVW1", "organism_name": "Caenorhabditis elegans", "protein_name": "Regulator of hypoxia-inducible factor 1", "length": 502, "firstPublicDate": "2015-06-24", "FUNCTION": "Involved in the response to variation in environmental oxygen levels by inhibiting hif-1-mediated gene transcription in a vhl-1-independent manner (PubMed:16980385), Plays a role in susceptibility to killing mediated by P,aeruginosa and by pore-forming toxins produced by B,thuringiensis (PubMed:20011506, PubMed:20865124), Probably by preventing hif-1 transcriptional activity, regulates behavioral responses, such as locomotion speed following acute reoxygenation (PubMed:22405203), Plays a role in normal egg-laying probably by regulating spermatogenesis and in body morphogenesis (PubMed:16980385)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSSPHTHTLIIMERLSEVRLYSSPMTSVLNSNLSSCLTNAFIPDTVRMASSPLLAWMTLVVIGTLAPVSVFSCLSLKRSVKELLTERSSKLDVLDIFRFVAILWVMLNHTGSEGRIDILDRLPSADAFKSAMHDHPIFGALMGNSALGVEIFLVLSGLLAARSWLRKADEPFFQHWKSFIARRLLRLAPSMFIFVYIAAGPIMNALLPRYSSSMVSACGFWGILSHVTFTSNWQSTPTCMGYLWYLGLDMQLYMVAPIFLNLLHKFPKRGMALTITTIIASMVIRAGYCTAYGTCNQSDVDIPFISYPGQDAETLKSIYAGLWDMYSRPYTKCGPFLIGLLLGYITVSSKYIMVSTTSKTLFRSSLIVAIATIYAILPEYWNPNAGNTLYNTVYTAVFRSVFAMAISGMIAALYFRQEYRPTNPIFAMLAKLTYNAYLLHMPVVYIFNWLPFLQAATSPIHLLLVLPFVAILSFIAALIFYLFIEAPIGHLTSQYATRLGL", "length": 502, "molWeight": 56103, "crc64": "35F88FE1E97E9432", "md5": "FBBFB9C4E5563ECA22E43BB5B94C1D62"}}
{"primaryAccession": "Q9Y0V2", "text": "This is Mitochondrial import inner membrane translocase subunit Tim10B protein, from Caenorhabditis elegans, contains 111 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y0V2", "organism_name": "Caenorhabditis elegans", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim10B", "length": 111, "firstPublicDate": "2001-01-11", "FUNCTION": "Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane, The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force, In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the small Tim family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNTIQNIQQLREFLTVYNTLSERCFNACARDYTTSTLTKDEGSCVSQCIDKQMLVNRRFMLVFAEQAPKALFKQGEQSPTEAIKSAKPEPAVPAPEATPVETTPVIEENKQ", "length": 111, "molWeight": 12456, "crc64": "C4B9154B15C7439F", "md5": "286F7319CB6F98D70DE1D790A6ADEB30"}}
{"primaryAccession": "Q9Y471", "text": "This is Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase protein, from Human, contains 501 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y471", "organism_name": "Human", "protein_name": "Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase", "length": 501, "firstPublicDate": "2005-05-10", "FUNCTION": "Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions, That protein has no CMP-N-acetylneuraminate monooxygenase activity and is not able to convert CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells in vertebrates (PubMed:9624188), However, it may play a role in Wnt signaling (PubMed:19890979)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CMP-Neu5Ac hydroxylase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDENNGLLLLELNPPNPWDLQPRSPEELAFGEVQITYLTHACMDLKLGDKRMVFDPWLIGPAFARGWWLLHEPPSDWLERLCQADLIYISHLHSDHLSYPTLKKLAGRRPDIPIYVGNTERPVFWNLNQSGVQLTNINVVPFGIWQQVDKNLRFMILMDGVHPEMDTCIIVEYKGHKILNIVDCTRPNGGRLPMKVALMMSDFAGGASGFPMTFSGGKFTEEWKAQFIKTERKKLLNYKARLVKNLQPRIYCPFAGYFVESHPSDKYIKETNTKNDPNELNNLIKKNSDVITWTPRPGATLDLGRMLKDRTDSKGIIEPPEGTKIYKDSWDFEPYLEILNAALGDEIFLHSSWIKEYFTWAGFKDYNLVVRMIETDEDFNPFPGGYDYLVDFLDLSFPKERPQREHPYEEIHSRVDVIRHVVKNGLLWDELYIGFQTRLQRDPDIYHHLFWNHFQIKLPLTPPNWKSFLMCCEQNGPVILQFSTERTNEPNRNKFSVENKA", "length": 501, "molWeight": 58380, "crc64": "7C340A121B5ACA4D", "md5": "88BC6456FF8B565609C6AA9193E56C48"}}
{"primaryAccession": "Q9YGJ8", "text": "This is Venom plasminogen activator Haly-PA protein, from Korean slamosa snake, contains 258 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9YGJ8", "organism_name": "Korean slamosa snake", "protein_name": "Venom plasminogen activator Haly-PA", "length": 258, "firstPublicDate": "2007-07-24", "FUNCTION": "Snake venom serine protease that activates plasminogen, Displays indirect fibrino(geno)lytic activity through conversion of plasminogen to plasmin, Shows a preferential cleavage at Arg-|-Xaa instead of Lys-|-Xaa bonds", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family, Snake venom subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALIRVLANLLILQLSYAQKSSELVVGGDECNINEHRSLVVLFNSSGLICSGTLINQEWVLTAAHCDSKNFQMLFGVHSKKILNEDEQTRDPKEKFICPNKKKDDEKDKDIMLIRLDSPVSNSEHIAPLSLPSSSPTVDSVCRIMGWGTIKPADETYPDVPHCANINILDHTVCRAAYPVLLAGSSTLCAGTQQGGKDTCVGDSGGPLICNGQIQGIVSWGAHPCGQGSKPGVYTKVFDHLDWIKSIIAGNTAVTCPP", "length": 258, "molWeight": 27813, "crc64": "B5B341E689D23AFF", "md5": "F78EC04BCFB604FFB379B7A832FF7644"}}
{"primaryAccession": "Q9ZNV4", "text": "This is Cytochrome B5 isoform C protein, from Mouse-ear cress, contains 132 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ZNV4", "organism_name": "Mouse-ear cress", "protein_name": "Cytochrome B5 isoform C", "length": 132, "firstPublicDate": "2012-10-03", "FUNCTION": "Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases, including fatty acid desaturases", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the cytochrome b5 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MANLISFHDVAKHKCKNDCWILIHGKVYDISTFMDEHPGGDNVLLAVTGKDASIDFEDVNHSKDAKELMKKYCIGDVDQSTVPVTQQYIPPWEKESTAAETTKEESGKKLLIYLIPLLILGVAFALRFYNNK", "length": 132, "molWeight": 14873, "crc64": "894A1133E88596BC", "md5": "191EE6BC47B0EDBBE5F686765927A3BB"}}
{"primaryAccession": "Q9ZQZ9", "text": "This is Protein TIC 20-IV, chloroplastic protein, from Mouse-ear cress, contains 284 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ZQZ9", "organism_name": "Mouse-ear cress", "protein_name": "Protein TIC 20-IV, chloroplastic", "length": 284, "firstPublicDate": "2011-10-19", "FUNCTION": "Involved in protein precursor import into chloroplasts, Partially redundant with TIC20-I, but not with TIC20-II or TIC20-V", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the Tic20 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQGLAATTTNRGSLTFLAPRNHSPISKKFVNPRVFFPNVDSSAKLRLSASSISRRCPREIAPLSATASVDFAAAATSSNQLFANGLPPLAPGLRRHRRPIEPARVAKDDFFKIKLPKIAERPEWWWRTLACVPYLISLQISDVGFYVQPFLEKHDAIGDMIYFIPGAINRWPTWFFMVYCYLGYMWVVKNKELPHYLRFHMMMGMLLETALQVIWCTSNFFPLIHFKGRFGMYYWMAIGFTYICLLLECIRCALAGVYAQIPFMTDAASIHTLFNLGGFQRPLR", "length": 284, "molWeight": 32520, "crc64": "8E806195D98C943C", "md5": "2778027BF81003A8F193E16A8005C55B"}}
{"primaryAccession": "Q9ZVL6", "text": "This is UPF0603 protein At1g54780, chloroplastic protein, from Mouse-ear cress, contains 285 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ZVL6", "organism_name": "Mouse-ear cress", "protein_name": "UPF0603 protein At1g54780, chloroplastic", "length": 285, "firstPublicDate": "2008-07-01", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the UPF0603 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "METLLSPRALSPPLNPKPLSLHQTKPTSHSLSLSKPTTFSGPKHLSTRFTKPESRNWLIDAKQGLAALALSLTLTFSPVGTALASEFNILNDGPPKETYVVDDAGVLSRVTKSDLKKLLSDLEYRKKLRLNFITVRKLTSKADAFEYADQVLEKWYPSIEEGNNKGIVVLITSQKEGAITGGPAFIEAVGENILDATVSENLPVLATDEKYNEAVYSSAKRLVAAIDGQPDPGGPTVKDSKRESNFKTKEETDEKRGQFSLVVGGLLVIAFVVPMAQYFAYVSRK", "length": 285, "molWeight": 31139, "crc64": "E12D49A659844300", "md5": "138894B12A297AA18A2D73A67264ACC1"}}
{"primaryAccession": "Q9ZWT2", "text": "This is Cytochrome B5 isoform D protein, from Mouse-ear cress, contains 140 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ZWT2", "organism_name": "Mouse-ear cress", "protein_name": "Cytochrome B5 isoform D", "length": 140, "firstPublicDate": "2012-10-03", "FUNCTION": "Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases, including fatty acid desaturases", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the cytochrome b5 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGGDGKVFTLSEVSQHSSAKDCWIVIDGKVYDVTKFLDDHPGGDEVILTSTGKDATDDFEDVGHSSTAKAMLDEYYVGDIDTATVPVKAKFVPPTSTKAVATQDKSSDFVIKLLQFLVPLLILGLAFGIRYYTKTKAPSS", "length": 140, "molWeight": 15097, "crc64": "18C24FF8F7995E08", "md5": "C27CD625BF09B84C57C695130A26D59E"}}
{"primaryAccession": "A2RV66", "text": "This is Protein shisa-1 protein, from African clawed frog, contains 269 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A2RV66", "organism_name": "African clawed frog", "protein_name": "Protein shisa-1", "length": 269, "firstPublicDate": "2008-04-29", "FUNCTION": "Required for head formation during gastrulation, Functions as an inhibitor for the caudalizing signals wnt and fgf, does not inhibit bmp, activin and nodal signaling in head formation process, Induces retention of fzd8 in the endoplasmic reticulum and inhibits trafficking of fzd8 to the cell surface", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the shisa family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEFIVLLTVCALLGLSCGQHGEYCHGWTDSYGIWRPGFQCPERYDPPEATFCCGSCGLKYCCSTVESRLDQGLCPNEEDLRDGVPSIELPPTVPTYFPFLLVGSIFVSFVILGSLVGLCCCKCLKPEDDTQVSGPAPIQSRLLDQDPSTDTSRHSSSSSASMPRPPIGARPQNLCSLGAENINLYMNMPPTFPMMGCPQNAQFMHPGTAGPSFMQPPFINYAVPAEHAIIMAPAPYIDARNCYGQTSNIYCQVPQQNDQTVCSGSPSKC", "length": 269, "molWeight": 29184, "crc64": "E9275AC5AB0CD202", "md5": "B9064220543CDDF3DFCB3BDD784C306D"}}
{"primaryAccession": "A6XGK3", "text": "This is Metallocarboxypeptidase A protein, from Athlete's foot fungus, contains 422 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A6XGK3", "organism_name": "Athlete's foot fungus", "protein_name": "Metallocarboxypeptidase A", "length": 422, "firstPublicDate": "2009-09-22", "FUNCTION": "Extracellular metalloprotease that contributes to pathogenicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRSVLSLALLAANVVTAAVVSPFDYSGYKVIRVPTQKDNVKEVQRVITDLNLDTWKYPKSEGQNADIVVPPSQISSFMERISGMNIEMMHEDLGLSIRNETSFEAYSAGYAPDINWFKSYHSYQDHLSYLQDLQGLFRTRSEYVDAGKSHEGRTIPALHIWGSGGKNSKPAIIFHGTIHAREWITTMVTEYMAWSFLSQYNKNADITSIVDNFDIWIFPIVNPDGFAFTQTSNRLWRKNRQPNPNARCPGRDLNRNYPYQWVGPGSSSNPCSDTYRGAQPGDGTEIKVHIANMKKIAANKGIAMFVDWHSYGQLFMSPYGYSCTARPPTDARHQELSRIFAQALKAVHGTPYKTGPICNTIYQVNGDSVDYALEVLKVKLSLTAELRDTGARGFVLPADQIIPSGEETLAGTVAMLKAVIQG", "length": 422, "molWeight": 47106, "crc64": "11A5047BB434AF40", "md5": "E9604ADF3EB06C3D7BDDC124066518EA"}}
{"primaryAccession": "A7MAS3", "text": "This is ATP-dependent 6-phosphofructokinase subunit gamma protein, from Yeast, contains 351 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A7MAS3", "organism_name": "Yeast", "protein_name": "ATP-dependent 6-phosphofructokinase subunit gamma", "length": 351, "firstPublicDate": "2014-07-09", "FUNCTION": "Structural subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase, Not required for catalytic activity, Fine-tunes allosteric regulation of the ATP-PFK by ATP, fructose 2,6-bisphosphate and AMP", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVTKDSIIRDLERENVGPEFGEFLNTLQTDLNSEKPPIEQVKSQLETHFNLAHETQEFSRKNDNAPVDKLLTNYYNNYEVNVLEFVLQMGFSRDLSIPLNVWFVLDMISQLSTSKQDLPLDYYLVLNNSQTGKYSDFVRYLIYEAVGAEIHCFEQGSMPEQYRSSRWEDKVKGPALANRGPIRGNVGAGDRKITFHLLCKKTARMILVGDDRETDFEMSDRSFVTLLLDYYQRVGTTKKIDLLLLTNNFDTNMNNKLQQLKILESLNMLKSNCYVLDYQITVDQVTANFNSYVEGIPAFRRHEIANFLKKRKTPKNADELIFKYVGRWNICYQKKFHQGNISIHQISGYLD", "length": 351, "molWeight": 40796, "crc64": "CC66BE17B4D878F5", "md5": "063B023E32D220FA5104E84A90FCDCD9"}}
{"primaryAccession": "A7WNV3", "text": "This is Brevinin-1PLb protein, from Pickerel frog, contains 70 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A7WNV3", "organism_name": "Pickerel frog", "protein_name": "Brevinin-1PLb", "length": 70, "firstPublicDate": "2011-11-16", "FUNCTION": "Antimicrobial activity against the Gram-negative bacterium E,coli, the Gram-positive bacterium S,aureus and the yeast C,albicans", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTTKKSMLLLFFLGTINLSLCEEERNAEEERRDEPDEMNVEVEKRFLPLIAGLAANFLPKIFCAITKKC", "length": 70, "molWeight": 8098, "crc64": "53EB2667509CEB25", "md5": "DA9F168AA7BE1806BC4DBF2B4C7DD307"}}
{"primaryAccession": "A7WNV4", "text": "This is Brevinin-1PLc protein, from Pickerel frog, contains 70 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A7WNV4", "organism_name": "Pickerel frog", "protein_name": "Brevinin-1PLc", "length": 70, "firstPublicDate": "2011-11-16", "FUNCTION": "Antimicrobial activity against the Gram-negative bacterium E,coli, the Gram-positive bacterium S,aureus and the yeast C,albicans", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTLKKSMLLLFFLGTINLSLCEEERNAEEERRDEPDEMDVEVEKRFLPVIAGVAAKFLPKIFCAITKKC", "length": 70, "molWeight": 8097, "crc64": "A3D150F1C0544605", "md5": "66930858E8035869E639B9123E1241E8"}}
{"primaryAccession": "A7WNV7", "text": "This is Temporin-1PLa protein, from Pickerel frog, contains 62 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A7WNV7", "organism_name": "Pickerel frog", "protein_name": "Temporin-1PLa", "length": 62, "firstPublicDate": "2011-11-16", "FUNCTION": "Antimicrobial activity against the Gram-positive bacterium S,aureus", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Temporin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTSKKSLLLLFFLGTINLSLCEEERDADEEERRDDPDEMNVEVEKRFLPLVGKILSGLIGK", "length": 62, "molWeight": 7129, "crc64": "F542112628E6FC46", "md5": "6EC675F975148FECD9C4E254FD02689D"}}
{"primaryAccession": "A8B5P0", "text": "This is Pleurain-A2 protein, from Yunnan pond frog, contains 69 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A8B5P0", "organism_name": "Yunnan pond frog", "protein_name": "Pleurain-A2", "length": 69, "firstPublicDate": "2008-01-15", "FUNCTION": "Antimicrobial peptide, Has activity against the Gram-positive bacterium S,aureus ATCC2592 (MIC=15 ug/ml), the Gram-negative bacteria E,coli ATCC25922 (MIC=60 ug/ml), B,dysenteriae (MIC=60 ug/ml), H,pylori NTCT11637 (MIC=30 ug/ml), and the fungus C,albicans ATCC2002 (MIC=30 ug/ml), Has little hemolytic activity on rabbit red blood cells", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Pleurain subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTLKKTLLLLYFLGTISISLCKQERDADEDDGRKMTEEEVKRSIITMTKEAKLPQSWKQIACRLYNTC", "length": 69, "molWeight": 8075, "crc64": "E6062439CD84482F", "md5": "890111E13A1DB785A7A0463D6B816655"}}
{"primaryAccession": "B3A0P0", "text": "This is Mu-theraphotoxin-An1a protein, from Tarantula spider, contains 47 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0P0", "organism_name": "Tarantula spider", "protein_name": "Mu-theraphotoxin-An1a", "length": 47, "firstPublicDate": "2012-11-28", "FUNCTION": "Is toxic to insects, Reduces amplitude and frequency of spontaneous firing and inhibits voltage-gated sodium current (Nav) in the dorsal unpaired median (DUM) neurons of P,americana", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 12 (Hwtx-2) family, 01 (Ap1a) subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "IIECFFSCEIEKDGKSKEGKPCKPKGDKDKDKKCGGWRCKIKMCIKI", "length": 47, "molWeight": 5380, "crc64": "471B6483C9D9C713", "md5": "EBD80DEDA01BD7503645B8F0BE34DAD8"}}
{"primaryAccession": "B3EWT2", "text": "This is Toxin CSTX-17 protein, from American wandering spider, contains 40 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3EWT2", "organism_name": "American wandering spider", "protein_name": "Toxin CSTX-17", "length": 40, "firstPublicDate": "2013-02-06", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 02 (plectoxin) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "GCIPKHKRCTWSGPKCCNNISCHCNISGTLCKCRPGLFGW", "length": 40, "molWeight": 4410, "crc64": "440A14D3DC1DEC64", "md5": "4D5FBB5A1C0062D3043E605A5934A9A9"}}
{"primaryAccession": "B3EWT3", "text": "This is Toxin CSTX-18 protein, from American wandering spider, contains 51 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3EWT3", "organism_name": "American wandering spider", "protein_name": "Toxin CSTX-18", "length": 51, "firstPublicDate": "2013-02-06", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 02 (plectoxin) family, 07 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "GLWIKGNYCLRGRCLPGGRKCCNGRPCECFAKICSCKPKLIGKLSALKKHT", "length": 51, "molWeight": 5611, "crc64": "81A53D20E942BC58", "md5": "63187CDF3B770D65A16D0861879EE69B"}}
{"primaryAccession": "B5A9S9", "text": "This is Dybowskin-1CDYa protein, from Dybovsky's frog, contains 59 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B5A9S9", "organism_name": "Dybovsky's frog", "protein_name": "Dybowskin-1CDYa", "length": 59, "firstPublicDate": "2010-02-09", "FUNCTION": "Antimicrobial peptide, Has activity against the Gram-positive bacterium S,aureus (MIC=6 uM) and the Gram-negative bacterium E,coli (MIC=3 uM), Lacks hemolytic activity against human erythrocytes", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFTLKKSLLLLFFLGTINFSLCEEERNAEEERRDYPEERDVEVEKRIIPLPLGYFAKKT", "length": 59, "molWeight": 7067, "crc64": "E7856FF8B8FAF4C5", "md5": "C78FDC7958AE97EE205370B534284658"}}
{"primaryAccession": "B5BUZ8", "text": "This is Protein kintoun protein, from Chlamydomonas smithii, contains 675 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B5BUZ8", "organism_name": "Chlamydomonas smithii", "protein_name": "Protein kintoun", "length": 675, "firstPublicDate": "2009-03-03", "FUNCTION": "Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella, Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the PIH1 family, Kintoun subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPGKEENDTLEKSLKELNLTSDEMTKFEKAFKDPEFIKLFEEYAKEVSDPKVKAETDAYLRQIEQQGRAEDVYGAGTQLIVPDPAGAVIKTKVVSSSASKKQQQEQEKQEKEQQQQAAGAGKPEGPGKQGALPVGQKVFINICTCDKLERYSLTDAQDPATGRLRPKLTIPLSLGPVRQGADKQGAPAAVYDFVVHPDSWTFAAGNAAGLATLADTALDHVEQVGRCRLVRAWKRLNCRYKGTEGAAEPPVQCIRTSAAAAAGAAGEGAGGRVRPRPDVPGVPDLPGAKTAPPAAAGAAATAAAAAGAAEGGAGSSSRSTFSFDKSRKAGGTEAAGAVAKQEATITDPARPGYRHPDGAVTPEWGLLHRGEADLGEAWGDAGKGLAAGGRVPKELVVRVTLPDVSSAAPVDLDVGARCLALTVPNRYRLSVQLPYGVDDAKGRAKFDKARKVLEVTLPVVPPPAPPPGAAAAARAGLALIQELGGSEEAAEVKAEVEVEVADVMGRDQEAAHAKSEAGAGAGVKSPHTAAAASSGAAPAPAAASEEEEEEDKEDGGPAAGSGGDPAAAAAAAGASSGRELTENERKWRELHARQQQEEQEQQEAAEAAAAAAAAAAEPSSRSQLTGTVAQGGAAAAAESVAAAKQQVQQQPVAAAAAPTAVLRPRLNRELAMELD", "length": 675, "molWeight": 69211, "crc64": "73121E2511B9E31F", "md5": "E1B420536A906FD73C202CBBC0325D39"}}
{"primaryAccession": "B6GX22", "text": "This is Mutanase Pc12g07500 protein, from Penicillium chrysogenum, contains 445 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B6GX22", "organism_name": "Penicillium chrysogenum", "protein_name": "Mutanase Pc12g07500", "length": 445, "firstPublicDate": "2015-04-29", "FUNCTION": "Hydrolyzes 1,3-alpha-glucan predominantly into pentasaccharides, May enhance the efficacy of fungal antibiotics by degrading bacterial exopolysaccharides", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 71 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIWKSLFSALAILTHILPALTAPALDSELSSQSEDKYVFAHFMVGIVKDYQLEDWKEDMTTAQSIGIDAFALNCASIDSYTPTQLALAYEAAEQVNFKVVISFDFAYWTNGDTEKITEYMKQYAGHPAQMQYKGAAVVSTFVGDSFNWDAVKQNTPHPIYAVPNLQDPAEATTGPAKSADGAFSWLAWPTDGGNSIIPGPMTTVWDDRFVHFLAGKTYMAPVSPWFSTHFNTKNWVFVCENLPTLRWEQMLSLQPDLIEIISWNDYGESHYIGPYSAHHSDDGSSQWATNMPHDGWRNLFKPYIAAYKSGAKTPTVEADEVVYWYRPTPKGVVCTGDTLSAPMGADMLSDSIFVATMLTSPGTLTVQSGNNAPVDIEVPAGIVTSNVTMGVGAQSFKVARDGQTILSGQGGLDVKDSCVHYNFNVYVGSTKGGDGSNTTGARGSM", "length": 445, "molWeight": 48546, "crc64": "B134CE3F956DE79F", "md5": "EE54736797B418CABA36DD6882C5474B"}}
{"primaryAccession": "B6TVL4", "text": "This is Calcium sensing receptor, chloroplastic protein, from Maize, contains 395 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B6TVL4", "organism_name": "Maize", "protein_name": "Calcium sensing receptor, chloroplastic", "length": 395, "firstPublicDate": "2014-11-26", "FUNCTION": "Modulates cytoplasmic Ca(2+) concentration and is crucial for proper stomatal regulation in response to elevated levels of external Ca(2+), May function by regulating concentrations of inositol 1,4,5-trisphosphate (IP3), which in turn triggers release of Ca(2+) from internal stores, May play a role in de-etiolation", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPVPVSVSATLAPPPAAPPKTTSRSWERRAPADAAFAAASSVAGSAALLTLTPAAPAAALSKEDVAGSLTKAVDTVSQAIDVGGKAAEQVAAVLKALGEAVKPALPVLKSASDEALKLAAPVVSAASKQATEALQGAGVDPAPVLSVAKTAAEQSTKVIDAAKPVASAAVETITSLGPEDYVVAAGXAFLAYLLVPPVWSLVSSSLRGYKGDLTPAQALDKVTTQGYVLIDVRSEKDKAKAGLPQLPSNAKNKLVSVPLEDLPSKLKGMVRNAKKAEAEIAALKISYLKKIGKGSNVIIMDSYSDVAKTVAKTLDSVGFKNCWVMAGGFSGRKGWAQSRLGTDSYNLSVVEVVTPSRVIPAVAGRRTGTTAARIGTASSASRATTRKLLPGGVD", "length": 395, "molWeight": 40094, "crc64": "D410232AEB9BF01D", "md5": "E3B5FF7E3FE841DB05E7457CB004D597"}}
{"primaryAccession": "C0HJQ5", "text": "This is Potassium channel toxin alpha-KTx 8.7 protein, from Lesser Asian scorpion, contains 57 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C0HJQ5", "organism_name": "Lesser Asian scorpion", "protein_name": "Potassium channel toxin alpha-KTx 8.7", "length": 57, "firstPublicDate": "2015-05-27", "FUNCTION": "Inhibits voltage-gated potassium channel rKv1,1/KCNA1 at nanomolar ranges (IC(50)=8,5 nM)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 08 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSRLYAIILIALVFNVIMTIMPDMKVEAVSCEDCPPHCATKDQRAKCENDKCVCEPK", "length": 57, "molWeight": 6417, "crc64": "A6F6109B620FA3E2", "md5": "AEF4A31119BD5CDD87CD707DCEBA87A5"}}
{"primaryAccession": "C0HJZ6", "text": "This is Ocellatin-PT1 protein, from Ceara white-lipped frog, contains 66 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C0HJZ6", "organism_name": "Ceara white-lipped frog", "protein_name": "Ocellatin-PT1", "length": 66, "firstPublicDate": "2016-05-11", "FUNCTION": "Has antibacterial activity against Gram-negative bacterium E,coli ATCC 25922 (MIC=300 uM) but not against S,pneumoniae ATCC 700603, S,choleraesuis ATCC 14028 or Gram-positive bacterium S,aureus ATCC 29313, Shows virtually no hemolytic activity and no cytotoxicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Ocellatin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKDAGKQLVAHAMGKIAEKV", "length": 66, "molWeight": 7442, "crc64": "8C592BBED4C6C2F3", "md5": "EEA98BBD4C84ED2C6402EDC823466074"}}
{"primaryAccession": "C0HJZ7", "text": "This is Ocellatin-PT2 protein, from Ceara white-lipped frog, contains 66 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C0HJZ7", "organism_name": "Ceara white-lipped frog", "protein_name": "Ocellatin-PT2", "length": 66, "firstPublicDate": "2016-05-11", "FUNCTION": "Has no antibacterial activity against Gram-negative bacteria E,coli ATCC 25922, S,pneumoniae ATCC 700603 and S,choleraesuis ATCC 14028 or against Gram-positive bacterium S,aureus ATCC 29313, Shows no hemolytic activity and no cytotoxicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Ocellatin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKDAGKQLVAHATGKIAEKV", "length": 66, "molWeight": 7412, "crc64": "A1592BBED4C6C2E4", "md5": "7D1D749EEF5983BD464E08D58844949D"}}
{"primaryAccession": "C0HJZ8", "text": "This is Ocellatin-PT3 protein, from Ceara white-lipped frog, contains 66 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C0HJZ8", "organism_name": "Ceara white-lipped frog", "protein_name": "Ocellatin-PT3", "length": 66, "firstPublicDate": "2016-05-11", "FUNCTION": "Has antibacterial activity against Gram-negative bacterium E,coli ATCC 25922 (MIC=320 uM) but not against S,pneumoniae ATCC 700603, S,choleraesuis ATCC 14028 or Gram-positive bacterium S,aureus ATCC 29313, Shows no hemolytic activity and no cytotoxicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Ocellatin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVIDIIKGAGKDLIAHAIGKLAEKV", "length": 66, "molWeight": 7333, "crc64": "975B463670A6C82E", "md5": "8E79B4B51C52FE83070C43525E80C8D5"}}
{"primaryAccession": "C0HJZ9", "text": "This is Ocellatin-PT4 protein, from Ceara white-lipped frog, contains 66 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C0HJZ9", "organism_name": "Ceara white-lipped frog", "protein_name": "Ocellatin-PT4", "length": 66, "firstPublicDate": "2016-05-11", "FUNCTION": "Has antibacterial activity against Gram-negative bacteria E,coli ATCC 25922 (MIC=80 uM), K,pneumoniae ATCC 700603 (MIC=310 uM) and S,choleraesuis ATCC 14028 (MIC=310 uM), Shows no hemolytic activity and no cytotoxicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Ocellatin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKGAGKQLIAHAMGKIAEKV", "length": 66, "molWeight": 7398, "crc64": "8C5B463677C6C2F3", "md5": "C9CD85FC4B8FD70D0708972841E6A73B"}}
{"primaryAccession": "C0HK00", "text": "This is Ocellatin-PT5 protein, from Ceara white-lipped frog, contains 66 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C0HK00", "organism_name": "Ceara white-lipped frog", "protein_name": "Ocellatin-PT5", "length": 66, "firstPublicDate": "2016-05-11", "FUNCTION": "Has antibacterial activity against Gram-negative bacterium E,coli ATCC 25922 (MIC=300 uM) but not against S,pneumoniae ATCC 700603, S,choleraesuis ATCC 14028 or Gram-positive bacterium S,aureus ATCC 29313, Shows very little hemolytic activity and no cytotoxicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Ocellatin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKDAGRQLVAHAMGKIAEKV", "length": 66, "molWeight": 7471, "crc64": "8C592BBED4C6DDCE", "md5": "6DE1F1F80E155E6318C76D0919521A64"}}
{"primaryAccession": "C0HK01", "text": "This is Ocellatin-PT6 protein, from Ceara white-lipped frog, contains 73 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C0HK01", "organism_name": "Ceara white-lipped frog", "protein_name": "Ocellatin-PT6", "length": 73, "firstPublicDate": "2016-05-11", "FUNCTION": "Has antibacterial activity against Gram-negative bacterium E,coli ATCC 25922 (MIC=120 uM) but not against S,pneumoniae ATCC 700603, S,choleraesuis ATCC 14028 or against Gram-positive bacterium S,aureus ATCC 29313, Shows no hemolytic activity and no cytotoxicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Ocellatin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKGAGKQLIAHAMEKIAEKVGLNKDGN", "length": 73, "molWeight": 8169, "crc64": "1C71F2469552594C", "md5": "E3BC873F542A04DBE01633D78CD4D167"}}
{"primaryAccession": "C0HK02", "text": "This is Ocellatin-PT7 protein, from Ceara white-lipped frog, contains 73 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C0HK02", "organism_name": "Ceara white-lipped frog", "protein_name": "Ocellatin-PT7", "length": 73, "firstPublicDate": "2016-05-11", "FUNCTION": "Has antibacterial activity against Gram-negative bacteria E,coli ATCC 25922 (MIC=60 uM) and S,choleraesuis ATCC 14028 (MIC=240 uM) and against Gram-positive bacterium S,aureus ATCC 29313 (MIC=240 uM), Shows no hemolytic activity and no cytotoxicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Ocellatin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKGAGKQLIAHAMGKIAEKVGLNKDGN", "length": 73, "molWeight": 8097, "crc64": "1C71F2469550D34C", "md5": "5E5070D30905E57B1396777FFD5F1036"}}
{"primaryAccession": "C0HK03", "text": "This is Ocellatin-PT8 protein, from Ceara white-lipped frog, contains 73 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C0HK03", "organism_name": "Ceara white-lipped frog", "protein_name": "Ocellatin-PT8", "length": 73, "firstPublicDate": "2016-05-11", "FUNCTION": "Has antibacterial activity against Gram-negative bacteria E,coli ATCC 25922 (MIC=60 uM), K,pneumoniae ATCC 700603 (MIC=240 uM) and S,choleraesuis ATCC 14028 (MIC=240 uM) and against Gram-positive bacterium S,aureus ATCC 29313 (MIC=240 uM), Shows no hemolytic activity and no cytotoxicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Ocellatin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKGAGKQLIARAMGKIAEKVGLNKDGN", "length": 73, "molWeight": 8116, "crc64": "0CAB92469550D34C", "md5": "8DB25215943E009A0DCE2F5F7F61A3D2"}}
{"primaryAccession": "C5J888", "text": "This is OcyC3 protein, from South American scorpion, contains 75 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "C5J888", "organism_name": "South American scorpion", "protein_name": "OcyC3", "length": 75, "firstPublicDate": "2010-10-05", "FUNCTION": "Amphipathic peptide with probable antimicrobial activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the non-disulfide-bridged peptide (NDBP) superfamily, Medium-length antimicrobial peptide (group 3) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQYKTFLVISLAYLLVADEAAAFWATLAKGALKLIPTIANAFSSKSKKRREINNVFEPYHENLDLELERFLSQLQ", "length": 75, "molWeight": 8590, "crc64": "72490B7D614D30E2", "md5": "4232EC44427CBD0AD7E50209CF1293F8"}}
{"primaryAccession": "D2Y171", "text": "This is Conotoxin Cal5a L1 protein, from California cone, contains 76 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D2Y171", "organism_name": "California cone", "protein_name": "Conotoxin Cal5a L1", "length": 76, "firstPublicDate": "2012-01-25", "FUNCTION": "Probable neurotoxin with unknown target, Possibly targets ion channels", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRFYIGLMAALMLTSILRTDSASVDQTGAEGGLALIERVIRQRDAADVKPVARTNEGPGRDPAPCCQHPIETCCRR", "length": 76, "molWeight": 8272, "crc64": "87FDBC5169A78EC6", "md5": "7021003274F8BE6451576E99996517BA"}}
{"primaryAccession": "D4ALW9", "text": "This is Extracellular metalloprotease ARB_05317 protein, from Trichophyton mentagrophytes, contains 271 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4ALW9", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Extracellular metalloprotease ARB_05317", "length": 271, "firstPublicDate": "2011-04-05", "FUNCTION": "Secreted metalloproteinase that allows assimilation of proteinaceous substrates, Plays a pivotal role as a pathogenicity determinant during infections and contributes to the ability of the pathogen to persist within the mammalian host (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M43B family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRFSVLLTGLAAAGSIATAERTCGAVPPRAYEKEFTEALNSLSPEAASADLTAGITIDTYLHVLTSGQTGNIPDSQLQAQINAMNQHYSQAGVQFKLVKATRTDNANWASGRDEAGMKKALHMGTYSSLNIYFIPNLSSGLLGICYFPRANPSQTTIIMDGCMVRSGTVPGGETTNYNQGKTATHEVGHFLGLYHVFSENGSCVDADMVADTPAQSKKTSGCPSSQDSCPGGGVDSIHNYMDYSYDVCMNQFTPGQANRIAQSWRAFRAGH", "length": 271, "molWeight": 28942, "crc64": "75E49684957046F5", "md5": "5252961D228DFC40383498A9B717D0F2"}}
{"primaryAccession": "D4AS12", "text": "This is Probable metallocarboxypeptidase A protein, from Trichophyton mentagrophytes, contains 422 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4AS12", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Probable metallocarboxypeptidase A", "length": 422, "firstPublicDate": "2010-10-05", "FUNCTION": "Extracellular metalloprotease that contributes to pathogenicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRSVLSLALLAANVVTAAVVAPFDYSGYKVIRVPTQKDNVKEVQRIITDLNLDTWKYPKSEGQNADIVVPPSQISSFMERISGMNIEMMHEDLGLSIRNETSFEAYSAGYAPDINWFKSYHSYQDHLSYLQDLQGLFRTRSEYVDAGKSHEGRTIPALHIWGSGGKNSKPAIIFHGTIHAREWITTMVTEYMAWSFLSQYNKNADITSIVDNFDIWIFPIVNPDGFAFTQTSNRLWRKNRQPNPNARCPGRDLNRNYPYQWVGPGSSSNPCSDTYRGAQPGDGTEIKVHIANMKKIAANKGIAMFVDWHSYGQLFMSPYGYSCTARPPTDARHQELSRIFAQALKAVHGTPYKTGPICNTIYQVNGDSVDYALEVLKVKLSLTAELRDTGARGFVLPADQIIPSGEETLAGTVAMLKAVIQG", "length": 422, "molWeight": 47104, "crc64": "F9BCB27189424307", "md5": "A078596BA6826F292161E6C6755C7DBE"}}
{"primaryAccession": "D4AS41", "text": "This is Uncharacterized FAD-linked oxidoreductase ARB_02478 protein, from Trichophyton mentagrophytes, contains 588 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4AS41", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Uncharacterized FAD-linked oxidoreductase ARB_02478", "length": 588, "firstPublicDate": "2015-12-09", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the oxygen-dependent FAD-linked oxidoreductase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRSTAYLTALLSFLGATHAAPEGPRCRCTPDQSCWPSPGLWQTLNKTLSGNLVAVKPVGTVCHDPTYNGGLCDSVKGMQTDSSWRSAQPGAVQSINWETWPEKNESCYIDGPRQVPCGQGRIPLYSAVVQSPLDIQKTVRFASKYNLRLVIKNTGHDFLGRSTGPQSLQILTHNMKSINFTDNFVPEGKPDGRGIGQAVTIGAGVQLNELYEAAGKRGLTQVIGLSTTVGAAGGYIQGGGHSPLGPWKGMSTDHVLEYKVVTAGAKFVTANEYQNSDLFWALRGGGGGTFGVVTSVTLRTFKDPPTIVSQVNVTMDGKANESYWAAVEKFQAYLPTLSDGGCSGYYYMLPNVTLGPQSAAVIIAAFYYANKTDKAHVDNLYRPLFASLSSIPGINVASVSVPVSSSTEAFRSAFDQKPPRDGGGVNILGSRLFSRKLLEAPGGAANLTAALSKLDFKNLQPAIGHLVAGGQVAKNTHIQSALNPSWRKALVHLVISRDWSIDSTFAEQEKISTKLTAEEIPLLAAVEPDMGAYTNEADVNEPRFQQTFWGTNYNTLLRVKNRWDPRGLFFVRSGVGSEAWDKQGLCRA", "length": 588, "molWeight": 63347, "crc64": "E362F511BA469A79", "md5": "845BB262D81B82DD9692A3596B7E3932"}}
{"primaryAccession": "D4AUH1", "text": "This is Exo-beta-D-glucosaminidase ARB_07888 protein, from Trichophyton mentagrophytes, contains 882 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4AUH1", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Exo-beta-D-glucosaminidase ARB_07888", "length": 882, "firstPublicDate": "2015-11-11", "FUNCTION": "Hydrolyzes chitosan and chitooligosaccharides with retention of anomeric configuration (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MWFVFRPAAIPALLLTLGVSALSPLRPLVSTAGQHEVIPGWYLQSERHVSSSIFSLSFPGADVSSWYRMGPRGTVMAGLLENGVYNETHLFFSDNFKSLPDADFRDVSWLYREEFTLQPGSGQHFTLHTHGISSRGDIYLNGHRVASKDVQAGSYAGYQYDVTKHVLKGGNCLLIKAYPTNYLRDLALGFVDWNPYPPDNGTGIWRHVELSQSGPIRLSSPRVTTDFVPGVRVNDTNLTVKTDVHNIGQETIRGSIKGFIEGAQNQRQPISAPFTLKPGEQQTIEMNTTIQNPSVWWPASWGDQPLYTARISAFVGKIKSDGPKRRKFGIRHIESRVNDQDTVEFKVNGKPFFVMGAGYSSDIFLRFTVERITTIFQYVLDMGMNTVRLEGKQEHPELYDIADKMGIMIISGWECCDHWEGWKYNTEGFGQPWTDVDYPIANSSMLHEARMMQTHPSILAFLIGSDYWPNDQATNIYVDALRRMDWNAAIISSAAKRGFPKLLGPSGMKMDGPYDWVPPSYWFGDRLGAAGAGGFGSELGSGVGTPEIRSLKKFLSEEDMKDLWTKPNKVLYHMSAGVSQFRDRSIYNKALYARYGKPNSLDDYSLKAQLMDYEATRSEYEAYAAYKSHSNPTTGLIYWMLNPAWPNLHWALFDYYLKPMASYFGTKTGARIEHAIYDYREQAVYLINHSNSRSGARSVTVDLINIDGKSLSHSTMKADTTPLMSQKLSKVSGLDKNRDVSFLRLILKDDAGKVLSRNVYWLPQREDVLDWGNSTWYHTPVTEYADLTPLSKLRKADVRVDINIQGRTKTRVSLQNKSNHPAFFIRLNLLDKASGDEVTPVFWEDNYVTLWPHERIELGVTYPQTHRVELEVSGYNVEKKMV", "length": 882, "molWeight": 99868, "crc64": "6B4C4A147B1C9878", "md5": "03BD6EBFC7D9CC7C3DBEDDD25F200DA6"}}
{"primaryAccession": "D4AWC9", "text": "This is Probable leucine aminopeptidase 2 protein, from Trichophyton mentagrophytes, contains 495 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4AWC9", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Probable leucine aminopeptidase 2", "length": 495, "firstPublicDate": "2010-10-05", "FUNCTION": "Extracellular aminopeptidase that releases a wide variety of amino acids from natural peptides and contributes to pathogenicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M28 family, M28A subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKSQLLSLAVAVTTISQGVVGQEPFGWPFKPMVTQDDLQNKIKLKDIMAGVEKLQSFSDAHPEKNRVFGGNGHKDTVEWIYNEIKATGYYDVKKQEQVHLWSHAEAAVSANGKELKASAMSYSPPASKIMAELVVAKNNGCNATDYPENTQGKIVLVERGVCSFGEKSSQAGDAKAAGAIVYNNVPGSLAGTLGGLDKRHVPTAGLSQEDGKNLATLIASGKVDVTMNVISLFENRTTWNVIAETKGGDHNNVVMLGAHSDSVDAGPGINDNGSGSIGIMTVAKALTNFKLNNAVRFAWWTAEEFGLLGSTFYVNSLDDRELHKVKLYLNFDMIGSPNFANQIYDGDGSAYNMTGPAGSAEIEYLFEKFFDDQGIPHQPTAFTGRSDYSAFIKRNVPAGGLFTGAEVVKTPEQVKLFGGEAGVAYDKNYHGKGDTVANINKGAIFLNTRAIAYAIAEYARSLKGFPTRPKTGKRDVNPQYSKMPGGGCGHHTVFM", "length": 495, "molWeight": 53243, "crc64": "00C1363FF0787B33", "md5": "3037C30032438BB7943901FDB87E68C1"}}
{"primaryAccession": "D4B528", "text": "This is Probable leucine aminopeptidase 1 protein, from Trichophyton mentagrophytes, contains 373 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4B528", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Probable leucine aminopeptidase 1", "length": 373, "firstPublicDate": "2010-10-05", "FUNCTION": "Extracellular aminopeptidase which contributes to pathogenicity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M28 family, M28E subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLLSVLALSATATSVLGASIPVDTRAEKFLIELAPGETRWVTEEEKWELKRKGQDFFDITDEEVGFTAAVAQPAIAYPTSIRHADAVNAMIATLSKENMQRDLTKLSSFHNRYYKADFGKQSATWLQEQVQAAINSAGASRYGAKVVSFRHNWAQHSIVATIPGRSPEIVVVGAHQDSINQRSPMTGRAPGADDNGSGSVTILEALRGVLQDQTIVQGKAANTIEFHWYAGEEAGLLGSQAIFANYKQTGKKVKGMLNQDMTGYIKGMVDKGLKVSFGIITDNVNANLTKFVRMVISKYCSIPTIDTRCGYACSDHASANRNGYPSAMVAESPIDLLDPHLHTDSDTIDYLDFDHMIEHAKLIVGFVTELAK", "length": 373, "molWeight": 40730, "crc64": "5412848D97293AE0", "md5": "0CD684EF6975FAD2A78332D56A8B5F81"}}
{"primaryAccession": "D6PVB4", "text": "This is High osmolarity signaling protein SHO1A protein, from Hortaea werneckii, contains 321 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D6PVB4", "organism_name": "Hortaea werneckii", "protein_name": "High osmolarity signaling protein SHO1A", "length": 321, "firstPublicDate": "2011-06-28", "FUNCTION": "Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the SHO1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDYNNNRYGGGGGGSKFNLGHIVGDPFSLATIAIATAGWLIAFVSSIIANIDQEYPNYSWWALAYMFFVILGVTFAVAANAVYTYHVAMVGFLAAGLVFTTSSVNSLIYWSDKAKQAAAAGFILLSMVSIVWIFYFGSQPTASHRQTIDSFALHKDHAPSRASRHMTQSYRPETTHSAQHPQMYNSSQLAGFETSSPVTGYPGGAAGATKRESASAFPPPGQGGNFSNNQQPNPITSQNNPQNQHQQPQDLTSPSTTQQPTEYPYRAKAIYSYEANPDDANEISFNKHEILEVSDVSGRWWQAKKENGETGIAPSNYLILL", "length": 321, "molWeight": 34997, "crc64": "21085D4F8786979B", "md5": "50EF81D4635B69335134E93E544137BE"}}
{"primaryAccession": "D6PVB5", "text": "This is High osmolarity signaling protein SHO1B protein, from Hortaea werneckii, contains 320 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D6PVB5", "organism_name": "Hortaea werneckii", "protein_name": "High osmolarity signaling protein SHO1B", "length": 320, "firstPublicDate": "2011-06-28", "FUNCTION": "Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the SHO1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDYNNNRYGGGGGAGSKFNLGHIVGDPFSLATIAIATAGWLIAFVSSIIANIDQEYPNYSWWALAYMFFVILGVTLAVAANAVYTYHVAMVGFLAAGLVFTTSSVNSLIYWSDKAKQAAAAGFILLSMVSIVWIFYFGSQPTASHRQTIDSFALHKDHAPSRASRHMTQSYRPETTHSAQHPQMYNSSQLAGFETSSPVTGYPGGAAGATTKRESASAFPQPGQGGNFPNNQQPITSHTQQQQQQSQDLTSPAATAHPPTEYPYRAKAIYSYEANPDDANEISFHKHEILEVSDVSGRWWQAKKENGETGIAPSNYLILL", "length": 320, "molWeight": 34771, "crc64": "C29022807F5D9D14", "md5": "94FD4538642FF3262CDEFFDA6991AD1B"}}
{"primaryAccession": "F1NZP5", "text": "This is TLC domain-containing protein 1 protein, from Chicken, contains 252 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "F1NZP5", "organism_name": "Chicken", "protein_name": "TLC domain-containing protein 1", "length": 252, "firstPublicDate": "2014-06-11", "FUNCTION": "Regulates the composition and fluidity of the plasma membrane (By similarity), Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (By similarity), Does not appear to have any effect on LCPUFA synthesis (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGPGWRAPSAALVGGSVALFGALRRAALALPRPAAVRSRPGRVWRWRNLLVSFAHSVLAGLWALFSLWQSPELLSDIQDGYSVSGHLLVCFSSGYFIHDSLDIIFNQQSRSSWEYLVHHAMAISAFVSLIITGRFLVAAMLLLLVEVSNIFLTIRMLLKMSNVPSPALYEANKYVNLVMYFAFRLAPQVYLTWYFVRYVEVQGQGAFLMANLLLLDAMILMYFSRLLRSDFFPSLRKGSVGRDVDGEKFLID", "length": 252, "molWeight": 28348, "crc64": "D28A29A0E0047342", "md5": "43D6D3770F889DCAF88419920795E5C9"}}
{"primaryAccession": "G9M8X1", "text": "This is Calcium-binding protein SP84 protein, from Green rice leafhopper, contains 687 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "G9M8X1", "organism_name": "Green rice leafhopper", "protein_name": "Calcium-binding protein SP84", "length": 687, "firstPublicDate": "2012-04-18", "FUNCTION": "Binds calcium, During feeding of the phloem sap, protein is injected into sieve tubes of rice plants, This process may suppress the sieve-element clogging and facilitate continuous ingestion from sieve tubes", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMRAIYLLVVVCWAAAANASSDTVPAEVQTIVKTPGHQYDLYKKMVATISLPANANTEIHKGLNIKRPDNKVTKADIELYYWHKDLKYAVTKFLHLINDDGNKEELTAEEFSNDLQKLAFKVALVECHYQLSPGLRQACYADEILTYGALVLESDDITKFYKHLDNDKDNELKTEEVLKIQHTHKNKDNKIVAEELGAYSGAKKDTVTPEEFEEYVTQESIVDDFRECRSKKATEGTTDYDNVCLTNELVEYVNDDLTEIDISLLYRSVDTNNDNKIIIDELKAFTGITDDVKAKRILELLDMSATTPANAKPVVDYGEWRTYLRSPTVLLQLERDCAMKHNDQLEEINCMYKLLKNLLIDEHDPIWLEAWDLDHVILFEIFDADKDDGKVFKDDLKKIQKNFHFKTEATVTRYMVEADIDKDSFICLEEFDEYMDIPHMVYGTGECILHSRTKPDERGDCFVEETSDVVDNFKFIENAAFDTWFNHYDTNHNNKIEKEADGLLAKFNNDANVLTMFLEETGQGGLTVEPFEFNWYVKQQHLAHAYEDEKIVTALVQKFTAEQITKLHTELIKYINDEMTERDIEDLFDELDHNDDHELTQQDFPDCWNDVKDLLTHIDALIPEGDEDTTVNYLEFWAWINHPNPKKPQELIKKTFETDCTTKHATQKEEVACYVKTFKTKDKFKTA", "length": 687, "molWeight": 79605, "crc64": "6E75366A664CA6AC", "md5": "E88FF98886FA2A807760A4458C33ED44"}}
{"primaryAccession": "H2A0M3", "text": "This is Putative amine oxidase [copper-containing] protein, from Freshwater pearl mussel, contains 781 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "H2A0M3", "organism_name": "Freshwater pearl mussel", "protein_name": "Putative amine oxidase [copper-containing]", "length": 781, "firstPublicDate": "2012-06-13", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the copper/topaquinone oxidase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSLPKTANGMDKLKLCYLLLFYLGSSSLTEVSGAQTCEIDSVLCTSDLSEPDDPPIFHDLTTKEIKSVQTYLYHQRDLRLLRPGLAKINTSFIQGMELYLPNKKDVIHYLQSKVPTPKPPRAAVVTIFRGDCDPAVVEEYIVFPLPWPTQHRLHRKVPYYLRPFNDVEFATISDFLTKQVDGVLRQFLEESFGGRLINCGNRCLNFQFASPVGPSVSNEPGARKSWYWLHQLVEYSALHPVDFAVLMKIVGCVYTIEKVYFNNMYFNSLQEVALHYRNPSFPRLRIPYPVDSKQLFSKMERRGILFPEKPVSPPRQVEPEGKRYSVKYQEVKYMNWKFNFRLSPGLGPRLHNIRYHDRLIVYELALQDIVVFYSGAEPPHQYANFFDSSYMIGMNLQGMVPGVDCPTGATFIDSHILTESSLKPAKLINAFCVFEQNTGDFLRRHISKTSPDGPFYEGVPSIVLVLRAITTIANYDYTIDFIFHHNGVLQTKVVPTGYILPSLYTKQNENKYGFRLNNKLIGNLHHHLFNFKVDIDINGQHNRYETLDIVLDKTSHPVSKKPYDVWYQNKIKHNLRKTEMEALFKYDFDKPMHHIFYNNNLKSPEGNNMAYRLVNRGMSKSLLPECSGNEGTGAWMRHQIAVTKRKETELTSSSVYSAFGTKNPVVNFRNFYADNENIVDEDLVAWVTMGTYHIPHTEDLPVTHTPGLDLSFFLSPFNYFPEDPAMGSRDSVRIEAVDKNNLKRGIKIDKQTFPEKMTCKAPIGNYFEYILKRPNVIFDIQ", "length": 781, "molWeight": 89950, "crc64": "49A8CBC587935AF0", "md5": "D7743AB1F2C32C0F0AD8AD99084F670B"}}
{"primaryAccession": "J9VQZ4", "text": "This is Laccase-2 protein, from Filobasidiella neoformans var. grubii, contains 594 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "J9VQZ4", "organism_name": "Filobasidiella neoformans var. grubii", "protein_name": "Laccase-2", "length": 594, "firstPublicDate": "2016-04-13", "FUNCTION": "Laccase that catalyzes the oxidation of certain aromatic compounds, including L-dopa, to quinones, which then polymerize to melanin (By similarity), Able to oxidize a wide variety of aromatic diphenol and diamino groups in the ortho, meta, and para positions but not monophenolic groups such as in phenol, tyramine, or tyrosine (By similarity), Plays an important role in virulence (By similarity), Plays a role in dissemination to extrapulmonary sites but is not involved in pulmonary growth or in elicitation of cellular immune responses in the lung (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the multicopper oxidase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGGIIKLSFLFCSLISLVNSENTGKLPTAISDHSVPKATATTDPSVFVLSNDFEITDVPTTREYTFNLTEALASPDGYERLVYAVNNMLPGPVIEANTGDTVIVHVNNYLHEGQGIHWHGLRQNGTALMDGVPGITQCSIPPGGSFTYQFTVSHQSGTFWWHSHYSNSMADGIWGPLIVHSPNEPLQRGRDYDEDRIVAVTDWMHDESETIVEALISSEGYRGRPFPPQGDAILINGRGQTNCTATGSPSCTYPPPPEIHVPVNCRVRLRFISAASHPMYRISIDNHSMEIVETDGTAVYGPTIHEISISSGERYSVIINTTEGKEGDAFWLRTSVALDCMAQGVTQVGLAVVRYTGNGSITTAEPRTEAWTDLARPDTPCVGLDEMYHLSPRELVNASQTALESRVLDSKLGKFVDVYGNSFEGYGFNNVTYQNQINDPLLYVVQRGGTCNSSLIANATFADIGPVNIIINNLDSHIGHPYHMHGTEFQLMGRGTGALTLDDLPNTNLTLDNPTRKDTIWMQGGSWALLRIISDNPGVWALHCHIGWHLAKGKMAVVVVQPEAIKKIQWPESWMDLCANTDPNAFGPARRSVS", "length": 594, "molWeight": 65066, "crc64": "E71D60C20BD6C102", "md5": "5A4CADCDE40150C8DC1B9F5C69853CA1"}}
{"primaryAccession": "J9VY90", "text": "This is Laccase-1 protein, from Filobasidiella neoformans var. grubii, contains 624 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "J9VY90", "organism_name": "Filobasidiella neoformans var. grubii", "protein_name": "Laccase-1", "length": 624, "firstPublicDate": "2016-04-13", "FUNCTION": "Laccase that catalyzes the oxidation of certain aromatic compounds, including L-dopa, to quinones, which then polymerize to melanin (By similarity), Able to oxidize a wide variety of aromatic diphenol and diamino groups in the ortho, meta, and para positions but not monophenolic groups such as in phenol, tyramine, or tyrosine (By similarity), Plays an important role in virulence (By similarity), Plays a role in dissemination to extrapulmonary sites but is not involved in pulmonary growth or in elicitation of cellular immune responses in the lung (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the multicopper oxidase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGVVKLFFLSCSLVSLVSSEETGKSPTANYDHYMPKATATIDPSVFALSNDFEITDVPTTREYTFDITKALASPDGYEREVYVVNNMFPGPVIEANTGDTIIVHVNNHLEEGQSIHWHGLRQLGTAFMDGVPGITQCPIPPGSSFTYQFTVSHQSGTFWWHSHYSNSMADGIWGPLIIHSPNEPLQRGRDYDEDRIVFITDWVHDNSEVVIAALATPEGYKGSPAPPQGDAILINGRGQTNCTATGSSSCTYPPPPEIHVPVNCRVRLRFISATAHPMYRITIDNHPLEVVETDGTAVYGPTVHEISIAPGERYSAIINTSEGKEGDAFWLRTSVALGCMFGGIDQVGLAVVRYTGNGMVSTEEPQTTAWSDLAGATTPCAGLDQTYTLSPRESFSAPREFSQSHVFNSQRGAFVNVYGNTFQGYGFNNISYQNQIFNPLLSIVQRGGSCESTLVASTTFPDLGSGNIIINNLDGVIDHPYHLHGNEFQVIGRGTGALSLDNLTNIDFNLDNPVRKDTLWIQGGSWVVLRITTDNPGVWALHCHIGWHLTEGKLAVVVIQPGAIGHMEGPESWTNLCANTDPNAFGPARRSPSPSIQSSKTSTFQYLREVKGKVVKRRGAREA", "length": 624, "molWeight": 68107, "crc64": "CACD3577C439C6C2", "md5": "2BF1C8AD1373811DBDAD5278F23C8F12"}}
{"primaryAccession": "K7ZGS2", "text": "This is Jingdongin-1 protein, from Chinese torrent frog, contains 63 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "K7ZGS2", "organism_name": "Chinese torrent frog", "protein_name": "Jingdongin-1", "length": 63, "firstPublicDate": "2015-07-22", "FUNCTION": "The synthetic peptide has antimicrobial activity against Gram-negative bacterium B,dysenteriae (MIC=35 ug/ml), against Gram-positive bacteria S,aureus ATCC 2592 (MIC=4,7 ug/ml) and B,subtilis ATCC 6633 (MIC=9,38 ug/ml) and against fungus C,albicans (MIC=18,75 ug/ml), Has no activity against Gram-negative bacterium E,coli ATCC 25922 but exhibits low hemolytic activity at concentrations up to 200 ug/ml", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLTLKKSMLLLFFLGTINLSLCEQERDADEEERRDDDEMDVEVEKRFLPLFLPKIICVITKKC", "length": 63, "molWeight": 7464, "crc64": "CF9E4E7605A4766E", "md5": "A539D8C6409E06D7B8D159E5EFEFD9A8"}}
{"primaryAccession": "O13737", "text": "This is 2-hydroxy-palmitic acid dioxygenase mpo1 protein, from Fission yeast, contains 222 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13737", "organism_name": "Fission yeast", "protein_name": "2-hydroxy-palmitic acid dioxygenase mpo1", "length": 222, "firstPublicDate": "2009-05-05", "FUNCTION": "Dioxygenase that catalyzes the alpha-oxidation of 2-hydroxy fatty acids in an iron-dependent manner (By similarity), Involved in metabolism of phytosphingosine and is required for proper endoplasmic reticulum stress response (By similarity)", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the MPO1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTYLSRSYSFYAAYHSNPVNIKIHQVCIPLLLLTALVLLHNFVITLINSKLQINVAHLVGLAYQIFYVTLDPLDGLLYSPVLYLFSYILPSKLFTIFSRSLVNRSAAVVHVICWILQFIGHGVFEKRKPALLDNLIQSLFIAPLFAFLETGPFVGYYPSVVSKIRANIKLKDVGENYPNLSEFLFPPSMVEDAVSGVVEDASQLSYCIRPLRLSDIDDGIVF", "length": 222, "molWeight": 24993, "crc64": "3F153DCF9DE17114", "md5": "C58A1FED758CBDAAEC9B8A375D20CE99"}}
{"primaryAccession": "O13744", "text": "This is Small ribosomal subunit protein uS7m protein, from Fission yeast, contains 259 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13744", "organism_name": "Fission yeast", "protein_name": "Small ribosomal subunit protein uS7m", "length": 259, "firstPublicDate": "2007-11-13", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uS7 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRLIKQPLFRCASSGHLMKESLVFIHQTRTFQVGKFTSNEKYNEKIEDINERSNPQWDNAGLENLLNQLQDSVEQSASDDFMGELEKKIEVENEEPPLMGTNLWPSPSSSIVGLIDRPFQVDSTVQHLVNLIMRDGKKAKAEKIVATALSIIQKETGENPIDVLKQAIAEISPLMKLVSAKRFNKSVEFPMPLKERQRRRIALQWILGECKSSSPKRLSDRIVKEIIAIRSKTSNCFKKKDHLHRMCLVNRGNAPVRI", "length": 259, "molWeight": 29559, "crc64": "CEA2C5803C248794", "md5": "FF71003ABA715C000EFA2586FDF93234"}}
{"primaryAccession": "O13769", "text": "This is Ubiquitin-like-specific protease 2 protein, from Fission yeast, contains 638 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13769", "organism_name": "Fission yeast", "protein_name": "Ubiquitin-like-specific protease 2", "length": 638, "firstPublicDate": "2001-08-14", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the peptidase C48 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRDSKDALDDKSGSFTSLLPPFGKQRGTSPNDAIPIKSPLERLANSVTSPEKPTVRTAIQKDSPRRKQIDDDQTPPKHLKRSFQNVTVVSPRKKKTIDVVELPFTKGGYGGFYDPRPGCLKFTTHEINVSYTDTSIPVIHIPVQLLKRCCWLQGWRDNLVESPVHAIHLTLKNRDMKRITIGDSASLLFLYNPLHVESARAGLDLLDQSDFSLTSPSSAKEFKQLLTLKQSTIIPRTPQKTVRSIVKQTSSPHSSKMPKHSLPSSPTPFNSNSGDSLLSRIKNSNQSSSERPTANNGAQEQNQSSSSAGNTSNDFSTLCSQGSDKTLLSDASCTTILVYPFSGTNSIAITNTDLTRLNEGEFLNDTIVDFYLRYLYCKLQTQNPSLANDTHIFNTFFYNRLTSKDKDGKRLGHRGVRKWTQKVDLFHKKYIIVPINETFHWYLAIICNIDRLMPVDTKLEEQDEIVMSSVEQPSASKTRQAELTSNSPAILIFDSLANLHKGALNYLREYLLEEAFERKNVHLKSTDIRGFHAKVPQQSNFSDCGIYALHFVELFLETPEQVIANTLDKSLRRTDAKNFDQQWNLQKINTMRCDLKGLIRRLSTEWSSNNERQSLSSGSNDEEDKENDDDLAILPITN", "length": 638, "molWeight": 71917, "crc64": "0F83228A45C50020", "md5": "6B23D1468F452B676A8A23E5815A5B54"}}
{"primaryAccession": "O13968", "text": "This is Uncharacterized carboxypeptidase C24C9.08 protein, from Fission yeast, contains 596 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13968", "organism_name": "Fission yeast", "protein_name": "Uncharacterized carboxypeptidase C24C9.08", "length": 596, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the peptidase M20A family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSTSNDPVVSSHDPIKQEKEQETDLEAQVEHKKRNERGNAFVGFLILIFVYYLLRGGSNDNDKQEMSHSPGSCMDSESAAVSTSAKCYIPPVLTPAKEPKLGDDVSGIDYIRSPEFFNDSLVRFQELLRIPTVCYDDMGDVGDDDRFDIFAVFQDKVRELYPNIFKKLKVEYVNTYGLLITLEGSNKDLKPLVLMGHQDVVPVNQASLDRWYFPPFSATYHNGHVYSRGAADDKNSVVAILEALEILAISDYKPEQTVIASFGFDEEVSGYRGALPLAHKLYERYGKDGVALILDEGGFTINLFGTLFATVCVAEKGYMDVHLKLKTPGGHASIPPPHTNIGLMSKLVTQIEEPFGGELTFENPFYTTLQCFAENSADMDDNLRQLIKSGDTEKMTDLFSKSRLYRYFFETSIAVDVINGGVKVNALPEETTLAVNHRVDASKGLKQVYDRYGGLLEEFGHEYHVNVTLFNGETVVEYEDAIGHIFASTAKTLEPSPVSPYDESSDAYKKLAGAIRYTFGDGTSVTPALMPANTDTRHYWNLTSNIYRWTPVSTNSTSKNSFNGHTINENMRYDAHMDSIEFFYNFILVSDSGEEA", "length": 596, "molWeight": 66607, "crc64": "D97A3930744364C1", "md5": "B199F252EE746ACFD7AB810B11266217"}}
{"primaryAccession": "O14013", "text": "This is RNA polymerase I-specific transcription initiation factor rrn5 protein, from Fission yeast, contains 556 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14013", "organism_name": "Fission yeast", "protein_name": "RNA polymerase I-specific transcription initiation factor rrn5", "length": 556, "firstPublicDate": "1998-07-15", "FUNCTION": "Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex, UAF seems to stimulate basal transcription to a fully activated level", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSSINGLNESEGSTPLSTASIIGSSEQLYMTHDERYLDVLQQYEVETENKRDFDLEEEQWGVLSGSCVDGTYWSAEEKELFFQAVARNGKRDLDLIAYSIPSKSAVQIERYINALENELRWLRNHVDASVRSQCLLKYEDIPIAMEMSQNWIDWEEKIAERLLEGSNISGVETSHYNAQSVKNKTSNEDLFDTNEMRKISERFYHFDRQAPFPSNPLSAGATEFLLQIIKSKLKELIGTSIFLAESRFRKLEANNAFHRKPIIKNRDVVLSGKFLRFHRFNIPGFWKYLPTRQKMNVYKRNKRLKFQNYIHIMESDERQSKLKLGRVRARKTKNNENTMFFDSKEHSTDESDGNLGEHDVKRKVDSVPADETSINGFKKSVNQAEYPDNAQMFMDESVAEESLVEIDDSVEAYDMIQSKNYESFVWKYVLHLTDEMSTEDALFETIPLSNLLAQKRMKDKLKGSDVFTTLKITSKSLHNIDEHSDSDDEVQPICYYYKDPVVSHAPGAAEVVSELESGYVGLISYDLSNLPNSTEDPERKLAKPVSSWELSLPLK", "length": 556, "molWeight": 64026, "crc64": "A1F97509E1802B72", "md5": "F9ACDC415BAD5740EE452180B0176587"}}
{"primaryAccession": "O14121", "text": "This is Probable NADH-ubiquinone oxidoreductase C3A11.07, mitochondrial protein, from Fission yeast, contains 551 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14121", "organism_name": "Fission yeast", "protein_name": "Probable NADH-ubiquinone oxidoreductase C3A11.07, mitochondrial", "length": 551, "firstPublicDate": "2008-05-20", "FUNCTION": "Catalyzes the oxidation of NADH", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the NADH dehydrogenase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLFSRSILRGMPKAGIPKSPLALSASRNLRLANSVRFASDAASSPKSTTSKWKILKRTTLGLFATAVVLYGANVYRFRHPDPHQPLPDPSKKTLVVLGAGWGATSILRTIDTSLFNVIVVSPRNYFLFTSLLPSTATGSVHTRSIVQPIRYMLRHKSCYVKFYEAECTDVDADKKVIHIKKTTTDGVDLEQEIKYDYLVCSHGAETQTFNIPGIAEYGCFLKEIWDAQKIRARILHCLEQAQFKDLPAETRRRYVHTVVVGGGPTGMEFAGEMADFIEDDLKSWYPELADDFAVTLVEALPSVLPMFSAKLRDYTQSLFDSSHIKIRTNTALKKVTAENIHVEVKNPDGSKQEEVIPYGLLVWAGGNRARPLTKKLMEGSEEQNNRRGLVVDEYLKLKGYKDIFALGDCTHTAYAPTAQVASQQGAYLGQLFNKLGSLNFEKPSEDRHIALGDEMDSSTLISLANEKHASTKVFLPFKYSHQGSLAYVGHEKAIADIEVPWFGKQLHASGALAFYFWRSVYLSELYSLRNRTNVTLDWIRVKLFGRDISSL", "length": 551, "molWeight": 61675, "crc64": "FED02DB71DEB9281", "md5": "2AF16D7F21741A26B5A691160446CC4C"}}
{"primaryAccession": "O14254", "text": "This is Probable isocitrate dehydrogenase [NADP], mitochondrial protein, from Fission yeast, contains 439 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14254", "organism_name": "Fission yeast", "protein_name": "Probable isocitrate dehydrogenase [NADP], mitochondrial", "length": 439, "firstPublicDate": "1998-07-15", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLEVRAAVKAPFKLAAAGRGFMNMRMASSKSFQKITVKNPVVEMDGDEMTRVIWKIIREKLVLPYMDIKLDYYDLGIEARDKTNDQITVDAAKAILKNDVGIKCATITPDEARVKEYNLKKMWKSPNGTIRNILNGTVFREPILIKNIPKYIPGWTNPICIGRHAFGDQYKSTDLVASGPGKLELSFTPKGNPSAKETYNVYEFNGSGVAMSMYNTDDSIRGFAHSSFQMALQKKMPLYLSTKNTILKKYDGRFKDTFQEVYESDYKQKFEELGLWYQHRLIDDMVAQAIKSNGGFVWACKNYDGDVMSDVVAQAYGSLGLMTSVLIHPNGRTFESEAAHGTVQRHYMQYLKGKKTSTNSIASIFAWTRGLAHRGRLDGNERLVKFANALEHACVRCVEKGIMTKDLYLLSKSPNGYVDTFEFLDAVKSELDSELVNIA", "length": 439, "molWeight": 49479, "crc64": "CF68839E7C423F5D", "md5": "BFEA9AF3F060824975FCB7B633E01957"}}
{"primaryAccession": "O14279", "text": "This is Ribosomal RNA-processing protein 14-N protein, from Fission yeast, contains 154 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14279", "organism_name": "Fission yeast", "protein_name": "Ribosomal RNA-processing protein 14-N", "length": 154, "firstPublicDate": "2009-05-05", "FUNCTION": "Involved in ribosome biogenesis and cell polarity, Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in correct positioning of the mitotic spindle during mitosis (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SURF6 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTEVEERINAWNDGFEELLSYIPAKLYYREHTANQWKQKKSTLEEKKERRKMKFSLDGLVNDADDDSQKSSKWEQSSTMSDDTDVSDRHAESMSQIRGKLASKIQDLREKRKAGDLNQKRQNKRPVENEKDSQKGSGKSKVQKKKHKASPRAGF", "length": 154, "molWeight": 17905, "crc64": "328349D3362CCA76", "md5": "7DF0115C1D9EA6A49FB8AEAE5BA9339C"}}
{"primaryAccession": "O14336", "text": "This is Meiotically up-regulated gene 80 protein protein, from Fission yeast, contains 461 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14336", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 80 protein", "length": 461, "firstPublicDate": "2007-02-20", "FUNCTION": "Has a role in meiosis", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSFPYQHTSRSQVQPPLAAPGLSMFAPVSSSNSANSASSVAALLSHAPMYGLGQRRPSFLPGVSVPDTLSVRSGFSIPSSSHHPSAVPSLLSQHRLQQPQPRLYPSAPLNYYWPSYQSVPSAAPPPPSQQRYMPDSAVAYNPNQDQFGNSVNVSAACNNVSAPLIANNCAPSFYQSRHPVADVPVTNNTATTTSETDNTIPGNLNMPSVANVQQRISPVCKTNMEDQEETVYTGGVAAKLDYKMDQMVEYLSIMTCKLYARFLNNAQMHSLANSLPGLVFSFRKVVTQILTSTRLPRASCLLALSYLSDRLDAASQTTDFVNQWTKESLFFQICALLTTALILANKFLDDNTFTNQSWSQVTGFRTALLNSFEQDWLASMSWNLSPGPRGQKAWEWWSASYSLFTSSNATYSGEQKTYSPTTLSTNAPPSPSSGRSCSNCNYYYPYTPVGYYPVYNRYAMT", "length": 461, "molWeight": 50623, "crc64": "AECD3BDD40905892", "md5": "CF839B41599FA089D44473FA3F3ADD62"}}
{"primaryAccession": "O36025", "text": "This is GYF domain-containing protein mpd2 protein, from Fission yeast, contains 992 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O36025", "organism_name": "Fission yeast", "protein_name": "GYF domain-containing protein mpd2", "length": 992, "firstPublicDate": "2008-06-10", "FUNCTION": "Has a role in mRNA export from the nucleus", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the SMY2/mpd2 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNSEASVFSNMDWSQLAHSLHKKANNSSSSTTGAFPQLTSFTKPTATNGVDSPTSSHIDPSVSAKLDSQRKLSLKSGNMWDSLNAPSELTSKNPTVSSTTSSANPAIVSNGGSPFYKNPVVANNPSSTFDMSTNLFNSKNANTSFTNAFSNEGISPGFLRDCFPSSNSITTGTASPKLGSPFNHINRPVLDRSPSSFSQSRSAVSGNMNPGVGTLQQPQRAGSDTFPDLNTSSSNQPGGEPNVASANTHSLEILSSSAYHPSGSSNGISAGLTQSVASPVGQVDNLADFSQSPLRRGPSRFPTNSNVPVGNSMSIRDTDSPLNILVDKAKAKASIKENASQPVAPSASQREHSAVNSPAAAMSPSTAMFSSEAFPQHLASLIPPALLHWLYKDPQNNVQGPFTGVDMHQWYRAGYFPLGLPIKRLEEEEYYSLAFFIRQVGNQLEPFLVPLSPVTVQNASWNAQGTDLPLSNYLPESSEQNRGGNKHLELYPSTAEVSNVRNDESKANSLSEISYNQQSECRSSELNVNEDSANQKEESALGTSDNSDMYEKENTPIHHNESLNQLSKDLGSISLSEETKQEKPSKLKETVESKRLSTGVQKQSPAASKEIPVTSGSQTTAPKPSPWKSLPPKHLPSLDETISREMSIASSEALPQVEKSNSDQPPVAIPSTSKTGSPWAKVSDVSTSMAQEIQRMEKQNENLKSKVASNPVSQTSTNAKASTPALASGSIWGSPSVINAWANKPAALKSPLIKKNIQQAELAQNKQQSSVTTASPRSNALNANTPKAAAPSSNVTMKNVTSILETSTFEGEDTWSVVGPGGKIVNQQSPSAQQTTRSPSKVSATLNAGNSQASTSSKLQQVVSMSGHSPDFLAWCKISLKGLNEGVNYEEFLDMLLSLPAENNVETFEIISDSIYANSTIMDGRRFASEFTRRRIADLTGKDGQQSNNKSQSELGNSSGAWSQVVRNKPKQGTEWNSAFKVVTSKKNKKRV", "length": 992, "molWeight": 106142, "crc64": "4751B990B0C39345", "md5": "B00D6F0FC45BF7B5CFFF43E4BB3F80C4"}}
{"primaryAccession": "O42648", "text": "This is HMG box-containing protein C10F6.08c protein, from Fission yeast, contains 341 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42648", "organism_name": "Fission yeast", "protein_name": "HMG box-containing protein C10F6.08c", "length": 341, "firstPublicDate": "2008-06-10", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MENPPYHVSISKSEEIKYRQKCKDLKARIQEIQKGNQELLSKYEVIRRAVKRGRLERAILMEQLELQSEAKSREFGQRSEPSPPPPPEGIKIKISTKGAGNPSAKKLKISTEETSDTNVALNNTSEISHKSSNNSQPKDASVNDTDADFEQQNQVVQSKDEKITNTDPIPSPIITNLKTESSKSSGAKKATSNAKITDTMLFNHFSSIQKPKLKAEGSTLKGQALKKTLEDTWNNLTEEEKKPYHEGLLAAREKAREARRRRSAQNSAKLEKEKAKEKQKDKDQEQDTVSDKNQIDEIEKGQKEVDEEPVSEPTTSPILPPKNQEPIRMGGFTVVNRSSNA", "length": 341, "molWeight": 38244, "crc64": "ECCA0886F0095FBF", "md5": "C62A7365F6BB8A013BC8B299D52E60B3"}}
{"primaryAccession": "O42699", "text": "This is Large ribosomal subunit protein eL19B protein, from Fission yeast, contains 193 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42699", "organism_name": "Fission yeast", "protein_name": "Large ribosomal subunit protein eL19B", "length": 193, "firstPublicDate": "2008-09-02", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel, eL19 may play a role in the last stages of translation initiation, in particular subunit joining and shedding/releasing factors", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eL19 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MANLRTQKRLAASVLKCGKRKVWMDPNEISEISNANSRQNIRKLVKDGLVIRKPNLMHSRFRIRKTHAAKRLGRHTGYGKRKGTAEARMPSTVVWMRRQRVLRRLLRKYRESGKIDKHLYHTLYLEAKGNTFKHKRALIEHIQRAKAEANRTKLIQEQQDARRARAKAARQRRAKAVEEKREQIYTAAEKIEE", "length": 193, "molWeight": 22754, "crc64": "59692E2DD9F564EA", "md5": "D665F112A5A3461F57D9B5947E698521"}}
{"primaryAccession": "O42866", "text": "This is 3-oxoacyl-[acyl-carrier-protein] reductase protein, from Fission yeast, contains 236 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42866", "organism_name": "Fission yeast", "protein_name": "3-oxoacyl-[acyl-carrier-protein] reductase", "length": 236, "firstPublicDate": "2009-05-05", "FUNCTION": "Involved in biosynthesis of fatty acids in mitochondria", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the short-chain dehydrogenases/reductases (SDR) family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRKVLITGGSSGLGKRIAQIWSQKGHQCHIVGRNEFHLKETLQSLSVAKGQQHTLTIADVQSDMKNLKSIFESVEIDTVVHAAGVLQSSLCVRTSEKEIDSIICTNLVSAIKLSKMAILEWFRNKNSERDRLILNISSRLSTYALPGTSVYAASKAGLESFTKVLAAEVASKGIRVNAISPGYVDTPMLSSQIRAIAEKKVPIGRLASTDEIVDACTFLLDNRYTTGTILPITGGL", "length": 236, "molWeight": 25601, "crc64": "7F28C25E0C9251D9", "md5": "BFAFDD05E7982879E0C17C87F6228B2C"}}
{"primaryAccession": "O43002", "text": "This is Protein transport protein sec61 subunit beta protein, from Fission yeast, contains 102 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O43002", "organism_name": "Fission yeast", "protein_name": "Protein transport protein sec61 subunit beta", "length": 102, "firstPublicDate": "2004-02-16", "FUNCTION": "Necessary for protein translocation in the endoplasmic reticulum", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the SEC61-beta family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSTKASGSVKNSAASAPGGPKSQIRRRAAVEKNTKESNSGPAGARAAGAPGSTPTLLKLYTDEASGFKVDPVVVMVLSVGFIASVFLLHIVARILKKFASE", "length": 102, "molWeight": 10444, "crc64": "F4987A79A24C0B4B", "md5": "F4E8AD38FD8FBECF5DE2B7F23CFF083E"}}
{"primaryAccession": "O43013", "text": "This is Uncharacterized protein C2G2.14 protein, from Fission yeast, contains 533 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O43013", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C2G2.14", "length": 533, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSFNPAAGLLGKLKKLWNDTKNDYLEWERSQQGQISESVVKNHSPSKRKRRPSKEPSLSPKRRKNILNDQKKDEESIPNAGTQSQNFTHLSASKIRISDEDRIKPLVDLNQDHSFDMAYLTPASAPPPRFRFVPPKSDAKSHSAPRSLEGVTSLSDSHFNSLEANLKAISKDSNNKAHNNRYDESSLTNPEFSILVERLKSIEENLQSLQERISHCERSVSLSPSFAPPSNVKSPVQQHRSFVSSSARAKKNWGRQSNSPNSNKKTDHAYPGASMNTERGLIQNLEDSDDIHEESSDTLEEPLLINELNRTSFLNSNNNLKLNEAEENQNLLNLRSPKSSGKADNLTIKSSSNIDKVTSNDLYLDNNLQSHFKVTESQPTNLGRKEYSNSPFSIRARKDAATTSSSFESYHNTQTIQSPMKFTKATPLKDNESASVDESKVNVLSENQSLQADTATLEQLTPIPKARWNQLANKHPSLSNSAASPPVSSPGLRRSHIPVHEGLKHTRDGVAETKDALAKLREKMQERLKNHTS", "length": 533, "molWeight": 59583, "crc64": "80BFDFBD2BB37FC3", "md5": "AC8325B6FBC1A6156B4D8CDF3E085556"}}
{"primaryAccession": "O43031", "text": "This is Pre-mRNA-splicing factor cwf28 protein, from Fission yeast, contains 381 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O43031", "organism_name": "Fission yeast", "protein_name": "Pre-mRNA-splicing factor cwf28", "length": 381, "firstPublicDate": "2005-08-30", "FUNCTION": "Involved in spliceosome maturation and the first step of pre-mRNA splicing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SPP2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKRKAVLEAFSDSEDEDEKKLKGPQLITGFSAEEGVHYQNETIQRIHEKKRAPKIIHIASDENWMEKRKARFKKKETEVHEKPSQLPDSGLNYGLNIRVASSSAADNEIVDWKANNSNEKAQNKIATNKESTDILPEEVQLVLNDLNDDVKSANSANLQPITTNVVNEKDAYRKDIDELPEPSNMKDYSEIPVEEFGAAMLRGMGWNGQLSSKDAFDVNQRPTFLGMGAKPVDSELTELDIWKNPKKTMFLPVKPLESNSALNSQNEHTEVQKKSNSIDNLTPSSELFRKRSRDNNLSRESSVSSKHLDYNSRNYNKRDRDPDRTKYREYHSERRKQHRTDRYSDDYYQGRSYSYKKRSHRSDRYTERENPDRSYRSTRTL", "length": 381, "molWeight": 44215, "crc64": "E1542538B667549F", "md5": "60C4929AFE059F94C39CD5D5D38A339F"}}
{"primaryAccession": "O43082", "text": "This is Ribosomal RNA-processing protein 14-C protein, from Fission yeast, contains 233 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O43082", "organism_name": "Fission yeast", "protein_name": "Ribosomal RNA-processing protein 14-C", "length": 233, "firstPublicDate": "2008-12-16", "FUNCTION": "Involved in ribosome biogenesis and cell polarity, Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in correct positioning of the mitotic spindle during mitosis (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SURF6 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "METTEGKNDLRAKLAEKIQTFRSQRKATEKVDRALLLQRRKEKAKARAEAKKLAKKESKAKQESKVAAYDTGNSSDNIADEENDNHKSTITYGTLIVGDDKFSNGKLKVAGKKRGPTDVFGALKHLEAKKRRIESMDEEKRRKIEESDKWHRVLLQAEGKKLKDNEQLLKKSIRRKEKEKKKSSDAWKERKDNEKKAMLMRQQRREENLKKRRESKKSKKGKAPKKKKPSKKK", "length": 233, "molWeight": 27125, "crc64": "5148EC3FF992EA1C", "md5": "E3A2FE5A6B15DED3762D95325DC313DE"}}
{"primaryAccession": "O43090", "text": "This is Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial protein, from Fission yeast, contains 551 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O43090", "organism_name": "Fission yeast", "protein_name": "Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial", "length": 551, "firstPublicDate": "2008-05-20", "FUNCTION": "Catalyzes the oxidation of NADH", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the NADH dehydrogenase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSVSKARLQSVVRLSRTVPYSKTMVRSFHVSCAVKNSGNVPTPRNKSFFSRALEMAEVTSSLSMLGAVALFQSLRRLNNSSPKGKSGVPKKNIVVLGSGWGAVAAIKNLDPSLYNITLVSPRDHFLFTPMLPSCTVGTLRLPSITEPIVALFKGKIDPSNIHQAECTAIDTSAKKVTIRGTTEANEGKEAVIPYDTLVFAIGAGNQTFGIQGVRDHGCFLKEAGDAKKVFNRIFEILEQVRFNKDLSPEERARLLHITVVGGGPTGMEFAAEMQDFIDNDVKDMFPELQKDIHVTLIEAAPGVLPMFTKSLITYTENLFKNLNIKIMTKTVVKDVNEKNLIVQKTNPDGSKAMQEIPYGMLVWAAGITARPLTRTLMSSIPEQSGARKGLIVDEFFRVKGVPEMYAVGDCAFSGLPATAQVANQQGAWLAKNLNVEGKKFALHERIQALEKQLGEKEAPSQVAGLKQQVEQLKLEPFKYHHQGALAYVGDEKAIADLKLPFMKKMLPLQGIVGHTFWRLAYLNELISARSQFMVLIDWLKTRLFGRYDAKV", "length": 551, "molWeight": 60781, "crc64": "C8CE3C56F88108AC", "md5": "98266B8CDBDA2D3A1CB5F30D0B893D22"}}
{"primaryAccession": "O59711", "text": "This is Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] protein, from Fission yeast, contains 450 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59711", "organism_name": "Fission yeast", "protein_name": "Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]", "length": 450, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the saccharopine dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPSILLLGSGFVAHPTLEYLSRRKENNITVACRTLSKAEAFINGIPNSKAIALDVNDEAALEKAVSEHDLTISLIPYTYHATVMKAAIKHGKHVCTTSYVNPKMAELEEAAIKAGSICMNEIGVDPGIDHLYAIKTIEEVHKAGGKIKSFLSYCGGLPAPEDSNNPLGYKFSWSSRGVLLALRNSAKFYENGKLVEIDGKDLMETAKPYFIYPGYAFVCYPNRDSTVYQERYQIPEAETIIRGTLRYQGFPEFIHCLVDMGFLDETAQEYLSPEAPALPWKEVTARVIKAESSSEADLIKKISSIHKFKDEDDKKRILNGLKWLGMFSSKPVTPRGNPLDTLCATLEELMQYEEGERDMLILQHKFEVETKEGKRQTRTCTLLDYGVPNGYTSMAKLVGVPCGVATQQILDGVINTPGVLAPNDMKLCGPLIDTLAKEGIRLEEEIIDEE", "length": 450, "molWeight": 49938, "crc64": "1AEE17A423715C71", "md5": "431C79B82F77DB58F09B25E30510D352"}}
{"primaryAccession": "O59782", "text": "This is Probable sulfate permease C320.05 protein, from Fission yeast, contains 667 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59782", "organism_name": "Fission yeast", "protein_name": "Probable sulfate permease C320.05", "length": 667, "firstPublicDate": "2007-09-11", "FUNCTION": "Possible sulfate transporter", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the SLC26A/SulP transporter (TC 2,A,53) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSPSENHLLGPKTSFIDNRTSTSRPLHEIPSYQSLARRSSTWKRANIPQQKPSLVRRINYYIPVLHWLPNYSLRNIIWDVLAGCSTACLSVPIALSFAQTFLGVPPIYILTGTAIGPILYCLFTACPLISIGPEAGMCLLIAENIHQRVLSKADVPQETAILVTGLIAFIAGIINLAAGLFRLGFLDALVSPVLLRGCILSISMIIMINQGSVFFGFSGVKYKGSDFPIDKLMFLIRNMSKANIYTTILSCITISLLIGCRNLKSKLSAKYPRIVSIPDAVIILLLGSFLSKKFDWHSNYGIAILGEIKTTILLPKLPLPEKNKLHFITQSLQTGVMCSFLAFIDTVIAVKAISLQTNNLIRSNRELISLGAANIGSSLFCGLPICGGYLRTKCNIMSGARTQVATIACSVLILLATFFIMPVFSTVPTCMLASMVVSLGVSLFADAAVEIFKLARIRVWWELGIIFSIATCTMMFGLETGIIFGLSITVMQIIRHSTRSRIMFRSPTSNGTAEFILEDAASTLSHRTNPSSTAVESAPRILVVRIPEPLFFANVSQLEDRLNRLEKYGHPRMHPGETPYRRIEDIEVVVFDMVGVSSIDSSALFAFQRILKEYVEHQVEVHLVSLDPQVLHIFEKHGLLDLIGGYDHVQDSIKKVDALCDIELGV", "length": 667, "molWeight": 73468, "crc64": "1FA587A0BC27C284", "md5": "9DD9AD4CC4C773746D562D40C9525113"}}
{"primaryAccession": "O59811", "text": "This is Cytoplasmic 60S subunit biogenesis factor SPCC550.15c protein, from Fission yeast, contains 463 amino acids, has 4 C2H2-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [5, 30], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [70, 94], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [208, 231], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [259, 283], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "O59811", "organism_name": "Fission yeast", "protein_name": "Cytoplasmic 60S subunit biogenesis factor SPCC550.15c", "length": 463, "firstPublicDate": "2007-11-13", "FUNCTION": "Pre-60S-associated factor involved in the cytoplasmic maturation of the 60S subunit, Involved in the dissociation and recycling of other late pre-60S factors before newly synthesized large ribosomal subunits enter translation (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the REI1 family", "domain_description": {"C2H2-type Zinc finger": 4}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSTSFACTTCTVAFNNAESQKIHWKSDWHHYNLKRKVASLPPLSAEVFAGKILSIQKQNEEVQKKAEFYQNCEVCNKKFYSEGAYSSHMASKKHRDNLSKFQRNSRIKKLQSEDASSIASSTLSMGEPVVDSEIEEEEDLASQLTSRAISLSNLSLHGRESEPSKTELATSIPQSNEASKSHLFTQEPTPEEIEAELARRSSQRLSPRDCLFCAASFSSFDTCKKHMKASHSLYIPEREYLVDEPSLFDYLAEKISIGFTCLTCNREFKSLEAVRAHMQQKGHTSIAYDTEDEQLELSDFYDFTTSYPDYAVKQDETVVEEDGSSGEGDWEDVSDDSDNSSLDSLEMGRVPIADEYELHLPSGNRVGHRSLSRYFRQNLHSSSTAVGDGASIHQNVARRAMSGNARAYRQAVETSIAGVRDGRKNYSASHIKSFQDQRRREEFANKMGIKNNTKKHFRDALLQ", "length": 463, "molWeight": 52251, "crc64": "B9EF7ED9910AE9A9", "md5": "15709450FF92E70068D9B60133402EB7"}}
{"primaryAccession": "O59812", "text": "This is Glucose-6-phosphate 1-dehydrogenase gcd1 protein, from Fission yeast, contains 475 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59812", "organism_name": "Fission yeast", "protein_name": "Glucose-6-phosphate 1-dehydrogenase gcd1", "length": 475, "firstPublicDate": "2008-05-20", "FUNCTION": "Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis, The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the glucose-6-phosphate dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLSIIVFGASGDLATKMTFPALFALYVRKIIPEDFQIIGYARSKLSQEAANKIVTAHIPIDDTVGASQKALNTFVEHYKYVPGTYDKPESFEMLNSIIAEKETAPASECTRIFYLVLPPHLFAPVSELIKSKAHPNGMVTRLIVEKPIGFDYKSADAILSDLSKHWSAKDTFKVDHFLGEDMIDGFTAIRFANSMFEPIWNREHIESVRVDFREDFGCEGRGGYFEGAGILRDVVQNHLLQLLTLLCIEEPKSQDAEDIIKCKVDFLKSLHPVSKEDIVYGQYTKSANGKVPGYRELDGVADDSEVSTFCALQLRSEAPRWKGIPIIISAGKGLDRDYFEARITFKRREGGMFPTVDSSNVLVLRVYPKEFIALKGHIKQPGFSRQIVPVTLDVKYPEAFPDTWIHKAYEVVIADAINGKHTHFISDDEVRTSWKIFDDVLDTTGDLSPLPYAFGSHHGPDATLEFFKKRNLEWD", "length": 475, "molWeight": 53510, "crc64": "C2CBB43BD6E70C45", "md5": "B8E38004731AFF7FA00DBB98B67B6A2E"}}
{"primaryAccession": "O60065", "text": "This is Peroxisomal membrane protein pex14 protein, from Fission yeast, contains 286 amino acids, is membrane-bound, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60065", "organism_name": "Fission yeast", "protein_name": "Peroxisomal membrane protein pex14", "length": 286, "firstPublicDate": "2009-05-05", "FUNCTION": "Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor, The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm, Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the peroxin-14 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MREDLLRNSVEFLREKTVLDAPDVKKIEFLKSKGLTAEEIQEAFKLAKNPLFPSYPRFENTSNFVSRDWRDWFIMGVISTGFAWSAYSLVKKYIAPMFRAPSQNAYEADKNALDAKFLEAHKILENLDEQTRKLSERTEKQQDELDIALDDLEETLNTLKRTSENRDREIARISQDVYTMSTITLPQSLEQIKKSQEEALQNLSREISSLRCLQTDSKKDDTFATTSNSSIPVLENPLDTSEGFQTKKVGTASLPDWQISMHNEASKNIDFNDIDPAESYVAEDAY", "length": 286, "molWeight": 32814, "crc64": "26A73B1A935E6D77", "md5": "6E781017634C668F5917407FFC1E9E3B"}}
{"primaryAccession": "O60104", "text": "This is Mediator of RNA polymerase II transcription subunit 7 protein, from Fission yeast, contains 376 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60104", "organism_name": "Fission yeast", "protein_name": "Mediator of RNA polymerase II transcription subunit 7", "length": 376, "firstPublicDate": "2002-12-06", "FUNCTION": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes, Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Mediator complex subunit 7 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEPNEGVQLFSAFPPPPPYYKLFTRENIEKVISNMEKEAKHEDDANTLQPKTEEEIESLAKLFKKPSCLTSGTYQMFGDTWRLDEAIPSLKEFGIPELYKDIKDGEDEIEVVEYDPKSNAIVGTSFTRVHDYDKNSPIENEKILEDDQHTAMKEKDNESDKTMKDVEEKTEPSLKKEEEDIQMKEPLDSQDTGAVSASSVNEGFRADQKSKDGETSDLIKIPRRAYELRFLSRSLMLNFLELLGIMAKAPEQFPSKVENIRVLLLNLHHLINDYRPHQSRESLIMLLEKQLKHEESQVELLRTHNRQMTETLEKYKSLDFNMEKEGDVIQQLKSSIKKPLSGAEDEQKSRSMFSKNDEKLKKSLELMEDVIKRDLS", "length": 376, "molWeight": 43509, "crc64": "A2FFA4E9CFAAEE99", "md5": "87323964989719FC487AA1CD4781B66B"}}
{"primaryAccession": "O60118", "text": "This is Large ribosomal subunit protein uL13m protein, from Fission yeast, contains 157 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60118", "organism_name": "Fission yeast", "protein_name": "Large ribosomal subunit protein uL13m", "length": 157, "firstPublicDate": "2008-01-15", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSTLNGQTALAYAKVWHHVSAKNVPLGRLASQIATTLMGKHKPIYHPAADCGDVVVVTDCSEIGISGRKLENHKYYSHSGQPGHLKEWTMEEMAAKRGHKDLLRRAVGGMLPRNKLWDRRMKRLYIYDGAEHPYKANIFRSYHNPVSSQIAKELFSK", "length": 157, "molWeight": 17768, "crc64": "47E52BF7BBFA42D5", "md5": "D90DEA03A1707BC47DF03F931673AF41"}}
{"primaryAccession": "O60142", "text": "This is Pentatricopeptide repeat-containing protein 2, mitochondrial protein, from Fission yeast, contains 432 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60142", "organism_name": "Fission yeast", "protein_name": "Pentatricopeptide repeat-containing protein 2, mitochondrial", "length": 432, "firstPublicDate": "2008-02-05", "FUNCTION": "Mitochondrial RNA-binding protein that acts as a general translation factor", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQFIKRTFPRRAFVDLLLNRFCLREFATTYSVSVSNARKLVRKRLLIADALKFKEQVNNLNEFRNKKTKSSLIRNDGFKLAKNVSSLLQKESLEKALHLLYERSNAKKTVAYNLVLQYHLAKGHYNAAWSLYNDMKKRQQKPSDHTYSILLKGFCDAIEKNKQGNFSKLREYSEKVTASALKESNNVTSNLHHIRIISKCSLKLKSMVLVSMIIPSIKQTLDFYSGSQILRLLNDFSMFNPEQREEVLKMGTNLWNYFVLECQKKGIAVDESLICSFVKLLATSNSPQVRNVGLNILTKVMGLEYQIFEDSNLRYPLPPYCDCTSRSLVTALQVIRQIQNGDLLARYWKYFEESHKFDLNLQVYHEKLRNLVQQGQAAECLNTIKRMSHNGPFPTQQTFLIVLSLCKRPKFYSYTKSFLDLAKKLNVPVEAT", "length": 432, "molWeight": 50048, "crc64": "C395CB5D16C6AE5B", "md5": "F62B40F90490D797448FA9AB7448FC98"}}
{"primaryAccession": "O60155", "text": "This is Putative proline--tRNA ligase C19C7.06 protein, from Fission yeast, contains 716 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60155", "organism_name": "Fission yeast", "protein_name": "Putative proline--tRNA ligase C19C7.06", "length": 716, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the class-II aminoacyl-tRNA synthetase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSVDSLVSCLEQLITDDLKLVEHQEVSNGATWASALQSTKDVPSHALTKTIVLKPKTAKSQTVVPIILAALETTSTPSGIAAKAVGSKEARMAAADLVEEVFGIPPTDVGIFSVNKENASKVHVVLDAALIQHNGLLAFHPSSSAKTVFVSPAAVQTYLKSVGVNPIIVDFSAPGSATAPSKPAAQKKKAEPSKNDAAIENAALIGITVRKDADFPNWYQQVLTKSDMIEYYDISGCYILKPWSYSIWEAIQGWFDKEIKKLGVRNGYFPLFVSSKVLEKEKDHVEGFAPEVAWVTRAGTSELDEPIAIRPTSETVMYPYYAKWIRSHRDLPLKLNQWNSVVRWEFKNPQPFLRTREFLWQEGHTAHMTLEGATEEVHQILDLYARIYTDLLAVPVIKGVKSENEKFAGGMFTTTVEGYIPTTGRGIQGATSHCLGQNFSKMFNIVVEDPNAEIGPTGERPKLFVWQNSWGLSTRTIGVAVMVHGDDKGLKLPPAIALVQSVVVPCGITNKTTDQERNEIEGFCSKLADRLNAADIRTEADLRAYTPGYKFSHWEMKGVPLRLEYGPNDAKKNQVTAVRRDTFEKIPVPLNNLEKGVSDLLAKIQTNMYETAKAERDAHVVKVKEWADFVPALNKKNIVMIPWCNTTECEKEIKKNSARQVNGDEPEDEKAPSMGAKSLCIPLEQPSGEDAIIEGTTKCAGCGNLAKVWGLFGRSY", "length": 716, "molWeight": 78875, "crc64": "8C7BDEA8FFE782A5", "md5": "53174656A6164A1E52F244F5CB7E18C2"}}
{"primaryAccession": "O60161", "text": "This is U3 small nucleolar RNA-associated protein 4 protein, from Fission yeast, contains 710 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60161", "organism_name": "Fission yeast", "protein_name": "U3 small nucleolar RNA-associated protein 4", "length": 710, "firstPublicDate": "2007-10-23", "FUNCTION": "Involved in nucleolar processing of pre-18S ribosomal RNA, Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs) (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDIHRCRFIDYTPSAITAMAFSHKSGQNDSMPNNLLLAVGRASGNIEIWNPRNDWCLKTVLYGGVDRSIEGIVWSTGEEELRLFSIGFSTTITEWNLHTGKPLVNQDSNAGAIWSIAICDETKTLAVGCDDGSCVLFDISGGPGVIEFKRVLMRQTSRILSLDFQTKDHLVGGCADGVIKVWDLSTPNSAIISRMQVDRARKGEAALIWAVKSLRDGTIVSADSSGAVKFWNGKFFTLSQSFKLHLADALCLGVSANGDMVFSSGIDRKTIQYSREGGKREWVSNSFRRFHSHDVRCMAVFECKSLDVLISGGMDMMLAVIPVRQFNRKNHRMISAVPQRPRMAVAPKARLFMLWNDHEVLLWRIGSPGYRFLLKIVLADEENISHAAISPDGELIAISSVLRTKLYQLQYSDENVKVETVEDSFLSNIGASLLSFTVDKNKLILVSNDSEIFLIELSRLDSRQLEVFELSQPTSKKIAPRQRSNVSSMCDGICSIAVSSDGDYFAVADTVGNIFCYSLSNLTYSELPRVNTYVRAMAFRPDVRGRLAVATAGNQVYEFDVQSRKLSEWSKNNSTNMPKEFSQLLDKAFGAFFDSKHPSRFWIWSANWVSFFDLNLQLPAPRAAGKRKIEMNATVDGNLNDKKLANANSNGISNYGTGDSRCFWITHKYRPMLLVGSVGNSELLVVERPIADMLMSKSMPASFYEHKFGS", "length": 710, "molWeight": 79121, "crc64": "F7E06170AF75C075", "md5": "65D6F6F377BA3D058634893A8A164295"}}
{"primaryAccession": "O60167", "text": "This is ENTH domain-containing protein C19F8.03c protein, from Fission yeast, contains 649 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60167", "organism_name": "Fission yeast", "protein_name": "ENTH domain-containing protein C19F8.03c", "length": 649, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSPSKWLLTYERAVKKATKVKLAAPKYKHVEIILEATTEDPETLENVIQALCERLKEQSWTIVFKTLIVFHVMLKEGAPNTTIVALSQRPRILEVLKASSLLAQGKNIYNYSRFLSERAKQYGRLGVDYAQVGDAPKKKIREMKLENGLLRNVEGIQAQLRRLIKCQFVAEEIDNDIAITAFRLLVGDLLVLFKAVNIGVINVLEHYFEMGHHDAAQSLRIYKTFVNQTEDIINYLSTARSLEFVTKFPVPNIKHAPISLTASLEEYLNDPDFEENRKQYLQNKSGSPVEETAILNRKPTLRKKKSIPKKQNESSSTIQKENTVQQEASSSEEEAVKSLPETQRTTSRIETQEEEIKEEEMEGEEEEEEEEVPNYESENELEDKVGDLSLSLGVASSFVDEMLRERNNLSAEGTSASPSLDKKSESTNIVQPIPSHPNDSLNPFYNSSSPTYHPQPIPPQLQQVQLLSQMAGNQMANIQYTMNGMQQTGASPNTALNISQVNMYAQNNPVNPSTTNPFQNFLRQPSYQGMQFEQQQPTTIPLQPNIPVLNQQYPVMIPAMEDSRGPLPSPAHIMYPEGSPGFIQHSPNGFTHGHSASPVNIGQKLDVPERPMSTPYTASKNPFSTRELAEPTDLARNSISTESKNPFRS", "length": 649, "molWeight": 72985, "crc64": "25990078ACF20CC6", "md5": "E34A356948F63EF6709211ED3B81DBF3"}}
{"primaryAccession": "O60171", "text": "This is Transcription initiation factor TFIID subunit 10 protein, from Fission yeast, contains 215 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60171", "organism_name": "Fission yeast", "protein_name": "Transcription initiation factor TFIID subunit 10", "length": 215, "firstPublicDate": "2008-03-18", "FUNCTION": "Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK, Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation, TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation), facilitation of DNA opening and initiation of transcription, SAGA is involved in RNA polymerase II-dependent transcriptional regulation, At the promoters, SAGA is required for recruitment of the basal transcription machinery, It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation (gcn5) and deubiquitination (ubp8), SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac), SAGA interacts with DNA via upstream activating sequences (UASs), SLIK is proposed to have partly overlapping functions with SAGA, It preferentially acetylates methylated histone H3 (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TAF10 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSDINNNEPAENIEQPKQEPEDGNNSMSVDEQPETSSTNLPTGDNLAPMSVESPAHLNNEDSPKSDDSRERHGSNYVIEPHLELRDMAKDKTLENFLAQMDDYSPLIPDVLLDYYLSLSGFKCVDPRLKKLLGLTAQKFISDVAQDAYQYSKIRTGSSNASSTTFGAQNFGAGGASGIGSSGRRGDRGKTVLTVDDLSAALNEYGINLKRPDFFR", "length": 215, "molWeight": 23526, "crc64": "E314301007678DA8", "md5": "6EF5FACA6365616D0DBCE656080C71BD"}}
{"primaryAccession": "O64538", "text": "This is Auxin-responsive protein SAUR40 protein, from Mouse-ear cress, contains 134 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O64538", "organism_name": "Mouse-ear cress", "protein_name": "Auxin-responsive protein SAUR40", "length": 134, "firstPublicDate": "2015-05-27", "FUNCTION": "Provide a mechanistic link between auxin and plasma membrane H(+)-ATPases (PM H(+)-ATPases, e,g, AHA1 and AHA2), and triggers PM H(+)-ATPases activity by promoting phosphorylation of their C-terminal autoinhibitory domain as a result of PP2C-D subfamily of type 2C phosphatases inhibition, thus leading to the acidification of the apoplast and the facilitation of solutes and water uptake to drive cell expansion (PubMed:24858935), Plays a role in the regulation of cell expansion, root meristem patterning and auxin transport (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ARG7 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKPLIRRLSRIADSSSCNRNRSGDIHHPTSTYSSSVFLVKRATVASSVPSGHVPVNVGEDKERFVVSAELLNHPVFVGLLNRSAQEYGYTQKGVLHIPCNVFVFEQVVESLRSGIADDTSELIASLSGEDVSTE", "length": 134, "molWeight": 14600, "crc64": "CBDE03AEE62EAC0A", "md5": "D50DD2CC7A309F8F79651FAF1426E063"}}
{"primaryAccession": "O73753", "text": "This is Neuroblastoma suppressor of tumorigenicity 1 protein, from African clawed frog, contains 175 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O73753", "organism_name": "African clawed frog", "protein_name": "Neuroblastoma suppressor of tumorigenicity 1", "length": 175, "firstPublicDate": "2009-03-03", "FUNCTION": "May act as a tumor suppressor (By similarity), Cytokine that has an axial patterning activity, Acts like bone morpho-genetic protein (BMP) antagonist in embryonic explants, Blocks the bmp2 activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the DAN family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTIWFLIGFLLPVAIFAAPPPINRLALFPDKSAWCEAKNITQIVGHSGCESKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPIDSVWDVVTLECPGNEEFPRVDKLVEKILQCSCQACGKELSQEGAMFNVYLNTAEDSPAESLGHHQHRPPAREDDSPAQSHREGESEE", "length": 175, "molWeight": 19338, "crc64": "EF44115A1F58C0E3", "md5": "E27B5543F48C93A193425712EB724412"}}
{"primaryAccession": "O74172", "text": "This is Small ribosomal subunit protein eS25B protein, from Fission yeast, contains 88 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74172", "organism_name": "Fission yeast", "protein_name": "Small ribosomal subunit protein eS25B", "length": 88, "firstPublicDate": "2001-08-14", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS25 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAPKKKWSKGKVKDKAQHATVFDKSIIDRINKEVPAFKFISVSVLVDRMKINGSLARIAIRDLAERGVIQKVDQHSKQAIYTRAAASA", "length": 88, "molWeight": 9820, "crc64": "42E0209CABE74700", "md5": "B6C4D54F298B18599AE4DEF735129BC2"}}
{"primaryAccession": "O74308", "text": "This is Uncharacterized transcriptional regulatory protein C15D4.02 protein, from Fission yeast, contains 547 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74308", "organism_name": "Fission yeast", "protein_name": "Uncharacterized transcriptional regulatory protein C15D4.02", "length": 547, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEYHPSSQSPQVNPGMESQQGGYTYTYQQPAPPNSLHLQHPSILTRLPPLSSSVVSPSLASLPPFTPTSTYHSIAALTPPSYPQSSSAPSNNSYTIVPSPHDPSNAYSMHHVLQNTAPQSVPSPSPIEMVPPSPPKTGSNNSAPVTGKTVQSGNALNNSGLVKRQARKRTKTGCLTCRKRRIKCDERKPICYNCIKSKRQCEGYTHFPRPSGTFTASRRIPVSSLLSEPAPHGLAGQPTHPTFLYYIQSVAPSLCLWDACHFPPLSPYSSFSSIYWSSTVPELALRNPNISVALYAFASAKRHLTDDAVAFARQARVALTNITTTDSLLILVLLAVTQLYIPKSDIQLFNFAVDQVVKFDASLMTSPSDEIITYLLRRMFIRQVVLAGIVKPLASGLNPLPLLKCDLPPATTPTAVLDESLFHLGLRKLCHEKGLEPEFTKWSKNCPIDKADLPRLALLMIHAVFTSPVSLAQWVELILQNPDPTPAIHIARACLLAVHGVVDLGDLQMKVEKCVQSCEERQLQATISNFSTEVAQTNSSALAIGCQ", "length": 547, "molWeight": 59642, "crc64": "A65FD7D039B6CD18", "md5": "71BCD9E5C0BA84736926DF07B1EB0EAF"}}
{"primaryAccession": "O74356", "text": "This is Putative ATP-dependent RNA helicase C25D12.06 protein, from Fission yeast, contains 585 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74356", "organism_name": "Fission yeast", "protein_name": "Putative ATP-dependent RNA helicase C25D12.06", "length": 585, "firstPublicDate": "2008-09-23", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the DEAD box helicase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKCCPASILDRFNAIKVINVMGLRLNGRSVPWLLQTRKFINITSPRYTAGRPVILNENQLIRYLPNYTNKGDEEVTRRKKLHEPNGPKFHELPLNQNILDGLSTNFAEYKNSTPLQQRIINALMKSGVSFIVRGWNGSGKSFGAMLSTLSMYFEALKFLKHNPVAGKPVQSGCQVLFIVPNDNLAAQYQFWIERLLHGITEKEELQHIYKILTLTPASLDSFQNRPPYIGITTFPNLQHCIKKNQPILKQFTSQLQLLIVDESDLVIPDHGRSRRLSSPEILADKIFLSSFIQLCKKNLRINMDDENVGGMGIHSQLHGKGSIPTMVFMSASNSKNGVNYLSRYITDQLGIIGIDRKHQWYWNLTSTPSVFHYLIKAQAEPKTTKVTLTNLPYEFVRFNNSMHSIGDNNFSYNNSEAVLQIFAQSVPRILNIEAKKSKLENNILKCVMIVLPKEFNPHSFCNQYKGFAVGNRFWQCRTLSTESLNFSTNLNNVVFVANPSEIRGLHLPSITHIFHLWSTFSGVAYQHIAGRLGAMGQTGKIFNFIIPDYYKSNDFKKTDFRRCILFMLQRVGIRPKSYEFDDEHF", "length": 585, "molWeight": 66894, "crc64": "AFAB04B5447B73B5", "md5": "B1B2B45752FD1BBAAA00A69ADF853A4B"}}
{"primaryAccession": "O74362", "text": "This is Pre-rRNA-processing protein esf2 protein, from Fission yeast, contains 334 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74362", "organism_name": "Fission yeast", "protein_name": "Pre-rRNA-processing protein esf2", "length": 334, "firstPublicDate": "2007-05-01", "FUNCTION": "Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis, Required for the early cleavages at sites A0, A1 and A2 (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ESF2/ABP1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSTAEQLFGAEEEEKYVDQDLSEDEEDERFLKAIRSSRSTKPVVDVLKVKSESSADELEERDAHLDRFRRDSTFESETSDHEDFSGGSENELDEETTKNANSIKKISLEEVEKQRKAIKRSGVIYLSRIPPYMAPNKLRQILSQYGKIGRVYLTPESSAKRAQRLRNGGNKRVMYEEGWIEFESKRVAKSVAELLNTNQIGGKKSSWYHDDIWNMKYLPKFKWHHLTEQIAAENAARESRLKVEIEQGRKQLKQYMRNVENAKMIEGIRKKRSERDTLNVSTEFPEETKDLSEDTKPSKQARRFFGQKSIVSNRNMPTDNAKQQKVENVLRRVF", "length": 334, "molWeight": 38921, "crc64": "B65C4C91AC85B4F2", "md5": "4A511BBED86479AB570C60314AC92A3E"}}
{"primaryAccession": "O74434", "text": "This is Meiotically up-regulated gene 174 protein protein, from Fission yeast, contains 626 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74434", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 174 protein", "length": 626, "firstPublicDate": "2007-02-20", "FUNCTION": "Has a role in sporulation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLLKVSSCEPLVPIKQWIHTSQLDLSDSSSLVADLLYNIIKFNFSGLEDKRAIFTGYESIKRYTIGNEMFLQLAKDGFALPVSMSYGLFLEETDTLELRALPRSEGLHRGCEVLVLRLDSPNELKENIREWSSKFMNSKASQKQQMLSPETMQKVDLAGRASPRYQANDSWISKKRNAPLSSISQYANMPENYALNTKKSKISNENDTIFKANFQQNKYESLHAKQISASDLSLHQEFVSASIVQQPELNSLLTSQSKNSTPSESDSSSSESSSSVSDSSDLSSTSDSSSGDESSDTARQSSSDTISSNNVSVSVSLNTANEFSFPQGTFKAENEAVESEVAPSSSTPPTVEEISYLHYDEPSQYYFSSPSKLSSETTKVHRGCENTEKPSEEGKNFTTPLSDSVESENTWSNTLRSSVEDDNTGVSDDNKKSKLNAEFDGHVNNISVRPPGSGSSATKARNLRRKKARILKRLMQESNDTFSANESTVVANVPDSYLTKNDEEDSASLASLKVAPKYVSHPVSLSSNSFHTEFPIGSLMRFTVMDLNPVTCTPEISEKTGRVVDCSEEKVKIQLDLGDRLDLKFDVNGEVIRNRYGTTPDEELIEGIATYEWSSLSNVHKLELTN", "length": 626, "molWeight": 69240, "crc64": "ECE1BC64486CB82D", "md5": "0B6D50BB778515A1CE9F713BB7D98F74"}}
{"primaryAccession": "O74531", "text": "This is F-box protein pof7 protein, from Fission yeast, contains 361 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74531", "organism_name": "Fission yeast", "protein_name": "F-box protein pof7", "length": 361, "firstPublicDate": "2002-12-06", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSTVEDQLSLELETVNKDILLKKALLHYKDAIKSEREGNLGESLNKYRLAHKVHEDVESIYRRLERLQLCKRNEEEEMLNSDASEAMLTVSSVPSPTLTENESVNESVVPNILKLPDEVLLVILENCIRDLHDLRYLSSIALTCKHFAKALRADSLYRSFCYCSCEQKEWQQSIKSIEEELVEKYQQSWKTLFLKKPRSRFDGCYISVCRYFRPGTSDTSWNQPIHLITYYRYLRLYPNSTCIVYQSSNEPNDVVRNFSVQNTSLFSPMSSSPMFSNGNVALTGSWSMTPSGEMLIVYPASQTYTYVQKLQVRGIRLKWISFYSIHNYTSFTNEMPLTHNRDYVFSRVYSYTADSESLKRG", "length": 361, "molWeight": 41933, "crc64": "0269BAE9AEDEB5B5", "md5": "655C4E56A5894FBBF0F5863B7149FA2F"}}
{"primaryAccession": "O74561", "text": "This is Uncharacterized inositol polyphosphate kinase C970.08 protein, from Fission yeast, contains 967 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74561", "organism_name": "Fission yeast", "protein_name": "Uncharacterized inositol polyphosphate kinase C970.08", "length": 967, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the inositol phosphokinase (IPK) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQNAPKCYLPNSRKGRDVNFHDRGPETLKCLYDESEDNNNFTMHSESIGPKSLDSLSPRRLSNYSSAVDPRTTSLEDVPRLILTRSNSQEQTPLRTHTPVEYMSDSIHKSLADLQLGGSSYSVAESPVPVLQSSAVSEADDMASAHSAHPSRKASRSLRLFESSTSNNLETGNSTNTALHNVSSPLESVSERLSKSGSPSVGAQHDLDEVISEKDTSLSRRSSRGRSSAPKRRKDSGSSKTTATYIPHNPSKKSSQHLPLLPDASFELERSVSRSYQSPASTPRSSVSSVSSSPPEDHPFFHWNVDYPVTVRLEPFKHQVGGHTAFFRFSKRAVCKPLTRNENTFYETIEACHPELLPFIPKYIGVLNVTHTITKTEENDSTTEYVNTESSSKTPAPHKHTFNSCYQKKDYGYIPEVSVEQNRHIFPEWMLPDKRSHSYGSPKSLHHKSSSAGERPVSPTFVADIPPKTPWGTTLINRKLREEVLREVFAPKHARRRLGTRFHSRSSHRPSVFRDNSVAFGQLDNGNTSSRARDKDADPNKSLSCSVEDKHYDLHSAVAEENEEVDEELLNVPSNNQGKSYRRFSSDAVWEEPESNEFPRVSGTMEDYDSRESTGHTIKELRSTPNSHGTVPDDSIFAMDNEENSELPPPLEPAEIGDPFRSVNDPRRVLSLPHMASADEDHRIPASDNQNNNNNDANALAENSESQHSTQIERYIVIEDLTSGMKRPCVLDVKMGTRQYGIMATEKKKASQTKKCAMTTSRVLGVRICGMQVWHPWLQSYTFEDKYVGRDIKAGEEFQHALMRYLGKTDDDEDNSHLLVHHIPTIIRKLEQLEQIVRFLKGSRLYASSLLFLYDGEPPPSDKSSKEKVKPREIDIRIVDFANCVFAEDKELLAKATCPPQHKDTYDRGYVRGLRTLRLYFLKIWKEAKGMQIAERGYEDSLSNAYDELGGLMSYSNDDDSCGETST", "length": 967, "molWeight": 108719, "crc64": "B09B252004368A30", "md5": "E03E4DE89901D3708D473829B5D06E06"}}
{"primaryAccession": "O74734", "text": "This is Putative ribosomal recycling factor, mitochondrial protein, from Fission yeast, contains 244 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74734", "organism_name": "Fission yeast", "protein_name": "Putative ribosomal recycling factor, mitochondrial", "length": 244, "firstPublicDate": "2009-05-05", "FUNCTION": "Necessary for protein synthesis in mitochondria, Functions as a ribosome recycling factor in mitochondria", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the RRF family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFRIISKATLFQDSQRFHTSILSPRCAFHNGGILHKKAKDKDVKHDHDPEFANSFNKMLKSFEAKMQLVHEKLAKRFQEAVVLPSQGNFTQLEALFIPSKSIKAPTPSRLLREIAAVSQKGSQQIIIRPFEDVDIKNILKAIEDSRYPFVANKLNASTIEVKPQRTTLESRQQLAKVLEGYAKDSREQLSAMRTELKKEIAKNKKSKAWTSDDCYKAEAEMQTAFKNAINLLDSGLKSALKKVI", "length": 244, "molWeight": 27688, "crc64": "0849DE90425D0884", "md5": "2E39532848E7AC979D95A65E423FD6D5"}}
{"primaryAccession": "O74765", "text": "This is Probable proline--tRNA ligase, mitochondrial protein, from Fission yeast, contains 425 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74765", "organism_name": "Fission yeast", "protein_name": "Probable proline--tRNA ligase, mitochondrial", "length": 425, "firstPublicDate": "2008-01-15", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the class-II aminoacyl-tRNA synthetase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLQHLRNRASIEVLGKAIRKYNVPESANQLLIDMGFIQPSMPGIFQYLPLGLRVQNKICDLLHISMRSLGASAISLAHLSSKEIWEKSGRWQKTGSELFRLHDRNDREMCLAPTHEEDVTRTMATIIDSQKQLPIRVYQIGRKFRDELRPRGGLLRGREFMMKDLYTFDIDKASAMKTYEDVLQAYHTFFKEVGLPFVMVKAATGNIGGNLSHEFHYRHPVGEDVIYTCPSCHYSTNSEMLDLSKTSSDISCPNCNDQLTSTTAIEVGHAFYLGKIYSSKFNATVEVKNKQEVLHMGCYGIGVSRLIAAVAHVTKDAKGLVWPSSIAPWKVLVVPTSDNHIQSAETVYDATANVVGFDNVLLEDRQNRAFGYKMRDAELIGYPFVIVVGSRFQEEGICEIIVRSSGERYKLDKDSLHQVLLGNFL", "length": 425, "molWeight": 47932, "crc64": "B833CA619C00E4E3", "md5": "1CF1BB5A224797EF510BAA50DF3CCBF4"}}
{"primaryAccession": "O74879", "text": "This is Ribosome biogenesis protein enp2 homolog protein, from Fission yeast, contains 634 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74879", "organism_name": "Fission yeast", "protein_name": "Ribosome biogenesis protein enp2 homolog", "length": 634, "firstPublicDate": "2008-05-20", "FUNCTION": "May be involved in rRNA-processing and ribosome biosynthesis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the WD repeat NOL10/ENP2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSLKVQNPNNVRVYTVSGEGVTQRLPNWISKRKLKKDYALSHRIELLQDFEYPEASNRIKCTRDGKYAMATGVYKPHIKVFDFAEMSLKFERHTDAENVQFEILSDDWTKSVHLQTDRTVDFHSQGGIHYSTRIPKYGRDLKYHYPNCDLYLAAAGDEVYRLNLEQGRFLNPLKIESAQIDSPTGGVNVIDINPMHQLLAFGTDAGSVEFWDPRDRSRVGILEIPSTVPSTPYSDNSRSVTALKYRNDGLNVAIGLSDGATLLYDLRSSSPYMSKDQGYSMPIKSLHWMDSALDGTARVLSADSKIIKIWEKDTGKPFSSIEPTVELNDVCPIEGTGLILTANEGSPMHAFYIPSLNPAPRWCSFLDNITEEMEENPAPTIYDDYKFVTKKELLNLGLDHLVGTGVIRAYMHGFFIDNNLYEKARLIANPFSYEEHRQKIVKERLEKQRASKIRSQNRPKVNAGLASRLSYQENKLRKKTGVTDGPSILEDERFKNVFTDKEFEVDEDTLEYKQLHPSRSEARGLTAAEESEEEKEHTKGIKFSSDEESLSDMEEENETFDALVDRRKTEQQVSNEKTPQETIRSTPSGMEMTFKVEKKKKSKPVNRDEDSTSGKKKQVTQGRRSASKNVFRNM", "length": 634, "molWeight": 72239, "crc64": "42D3C50CD0A9DC71", "md5": "7A917EA7C70FB9E3AE19614D24174043"}}
{"primaryAccession": "O74942", "text": "This is Peptidyl-prolyl cis-trans isomerase 9 protein, from Fission yeast, contains 610 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74942", "organism_name": "Fission yeast", "protein_name": "Peptidyl-prolyl cis-trans isomerase 9", "length": 610, "firstPublicDate": "2008-12-16", "FUNCTION": "PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the cyclophilin-type PPIase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMDGASPVDRDVSPVGLPKKRIKQNHDQVFLHNLPDAPRYTKSYMHNAEIYKCFPTKSNYILSVSYDGYVKFWHKTPNGVEYIKEFHAHNAMLLSAELSQDERLFITGADDKSLKVFDVESIDLVNIIDLEFLPKAICCFNSPSLKTSLIAVSSAESPLIFFFESGGDGEVLYTVKKHTAPVHCLRYLSTLDCFLSIDIGGMVEYWSPEEPFQKPDTAELFNMKSQTDLYIFKKQKSVPTSLEVSHFENFWSTISYPDCKVRVFDTKSGRAILELDENPSNAAKKVEALFEKEDTESSYYMSHVELGRRIAIERDIEKHGLTVGTTAIFDESEKYLLYGSIVGIKVVSIDNGTVVRIYGKDEAVRFTRLSLYQQAPKKSNLPSLDVIASNNPLVEESFQKDPTLFATAWKKQRFYLFSNMSTKFTLSDRDVYNEQVLPVTNNEGRQENGNILLGKAAIIHTTQGDISIKLYPEEAPKAVQNFTTHAENGYYDNTIFHRIIKNFMIQGGDPLGDGTGGESIWKKDFEDEISPNLKHDRPFTVSMANSGPNTNGSQFFITTDLTPWLDGKHTIFARAYAGLDVVHRIEQGETDKYDRPLEPTKIINISIVYT", "length": 610, "molWeight": 69048, "crc64": "28D06D189C76DF3B", "md5": "4BB2E324E6D03EFBFCE4F74B14DDF55B"}}
{"primaryAccession": "O74974", "text": "This is U3 small nucleolar RNA-associated protein 25 protein, from Fission yeast, contains 652 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74974", "organism_name": "Fission yeast", "protein_name": "U3 small nucleolar RNA-associated protein 25", "length": 652, "firstPublicDate": "2009-05-05", "FUNCTION": "DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the UTP25 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAIESDLDGASMDELAGKSYEALLYLMNKNKKRKPEKKDDKEKSSKKVQKKNKVIESLNEMEVEMEDENENENDEQEAIQYYINVESQDADETLHQEAQDSSEDPFHQHFDYDDSEVIKNSIAAYDEGKLCKSIEESKLGVSQSFFPDVTKRLPCSCLSEIKNIDDLGLKQRILDSYKKQKPSGQLTSMQIELAKAMFNYQDVFFTNMSMKSHKLGTSLLALHALNHVFKTRDRVLKNSARISQNPELEFRDQGYTRPKVLILLPTRNSAFEFINLLISYSGTNQVENRKRFDNEFSIEKEVISEKKPEDFRYLFSGNTDDMFRLGVKFTRKTVKLFSQFYNSDIIVASPLGLRLAIGNKGDKKRDLDYLSSIEIAMVDQAHALVMQNWEHIECIFDELNGLPKEAHGCDFSRVRPWYLDQQARYMRQTILFSQYNNLDINSFFSHYMSNIAGKVKFRSLLHGVLNRLGYKVTQTFVRISVDSIIKVPDARFSYFTGSILVQLKKYSQSGILVYIPSYFDFVRVRNYMDEEGINYSAISEYSSVSDMTRARNLFYQGRTNIMLYTERAHHFRRFDFRGVKAVVMYGPPTNPQFYVELVRMPMRTISEGNLDSDAAKCRIMYTKFDSICLEGIVGYQRVSNMCHGKHEVFEFL", "length": 652, "molWeight": 75652, "crc64": "96BB732F2273DE6B", "md5": "FA05C1724628406CDFEFE190BD897CB6"}}
{"primaryAccession": "O74994", "text": "This is Ring assembly protein 3 protein, from Fission yeast, contains 746 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74994", "organism_name": "Fission yeast", "protein_name": "Ring assembly protein 3", "length": 746, "firstPublicDate": "2001-08-14", "FUNCTION": "Essential for actinomyosin ring assembly during cytokinesis, Has a role, in conjunction with F-actin, in assembling myosin II-containing proteins, such as myo2, at the division site", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTHELSSTPQIDLLNDILKNSVESNVFSDYQKKQIVTLILKSKISTAIVLLSPKSTAASEWNYLCNLQDLHECVLCVDTILPANLQTIAKRIFSLVLLPPLNDWCKQLRDAFLRFVSQPSICPTDFPLKLFFLSTVGIELLIVNEKIIPQKTQKYLLYELFSSPSSITANEIARLCQEANNRNYLLQSLTSATDARRAFLNNPNYRLLSAIIFQDGPSNLAFVLAKDCVLLARQPETIPVSFERMSSLLLMCLPSHPDFISPEFCHEWTELAERNGLQEEWLNILNTACNFKECRAIIHKECSEFIKDNHTSRVAILISMKLAFQYQLSQVIPTLKLLLQSKVYDSVLLEALRQSSTLGPVKQLIADDSCLLNNLSKLLLDTNISPLDASSIATIIYNMCKFKITKSEHERELNQLRNMAEASKTIDYKEDETAPTERRIQKILEYDILSKLFSAAKHYNSLNGLLAMILVHMANYKLARRKLVQIGALKFLTRQCFIQTQDSNAAFALAKILISVAPHSIFTKAFPSNRAIHPMSKLLSTNSADTEYPILLGKFEVLLALTNLASHDEESRQAIVQECWRELDELIIETNPLIQRATTELINNLSLSPYCLIKFIGDKDSDFENTRLHIVLALSDTEDTPTRLAACGILVQITSVDEGCKKILSLQNDFNYIVRMLTDQDEGIQHRGLVCICNIVYSKDQEIFNKFIKTPKAVETLRTYITKQAALKELQHEALVMIDSRLQGSK", "length": 746, "molWeight": 84472, "crc64": "A0158CEDB110D71E", "md5": "CA26688315ED5114A5613C70E392D561"}}
{"primaryAccession": "O76200", "text": "This is Kappa-ctenitoxin-Pn1a protein, from Brazilian armed spider, contains 83 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O76200", "organism_name": "Brazilian armed spider", "protein_name": "Kappa-ctenitoxin-Pn1a", "length": 83, "firstPublicDate": "2002-01-23", "FUNCTION": "Antagonist of L-type calcium channels (Cav1/CACNA1) (PubMed:10098851), In GH3 neuroendocrinal cell line, it reversibly inhibits the A-type potassium current but does not block other potassium currents or calcium channels (PubMed:10098851), Shows an important acetylcholine-mediated antiarrhythmogenic effect in isolated hearts (PubMed:21115025), In vivo, causes paralysis in the posterior limbs and gradual decreases in movement and aggression during 24 hours at dose levels of 5 ug per mouse (PubMed:10098851)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 02 (plectoxin) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MWFKIQVLVLAITLITLGIQAEPNSSPNNPLIVEEDRAECAAVYERCGKGYKRCCEERPCKCNIVMDNCTCKKFISELFGFGK", "length": 83, "molWeight": 9379, "crc64": "F1EF6F6F6107C9DC", "md5": "B41E0535559A3D80777DB3B4DC591707"}}
{"primaryAccession": "O82499", "text": "This is Translation initiation factor IF-1, chloroplastic protein, from Mouse-ear cress, contains 141 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O82499", "organism_name": "Mouse-ear cress", "protein_name": "Translation initiation factor IF-1, chloroplastic", "length": 141, "firstPublicDate": "2001-01-11", "FUNCTION": "One of the essential components for the initiation of protein synthesis, Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds, Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC), Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the IF-1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLQLCSTFRPQLLLPCQFRFTNGVLIPQINYVASNSVVNIRPMIRCQRASGGRGGANRSKPAKPQVKEGSNKTVIEGLVTESLPNGMFRVDLENGDNILGYICGKIRKNFIRILPGDKVKVEMSVYDSTKGRIIFRMSSRD", "length": 141, "molWeight": 15733, "crc64": "DC9D1427BE2A3277", "md5": "092122370BB2242EA08BD73E51DEB4D4"}}
{"primaryAccession": "O94091", "text": "This is Lipase 1 protein, from Yeast, contains 468 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94091", "organism_name": "Yeast", "protein_name": "Lipase 1", "length": 468, "firstPublicDate": "2000-05-30", "FUNCTION": "Hydrolyzes triglycerides", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGIAVFLAFISLIFASPLTVKSPLVDDFYTAPDGYESAKLGEILKLRKTPSKLSSMFFEIDIKNSWQLLVRSEDSFGNATAIVTTVIEPYNADPSKVLSYQTFEDSANIECSPSYGMQYGAPWSTVATQIDMALMVPMLKQGYYVVSPDYEGPKSTFTVGRQSGKATLDSIRAILKSNKFTGIKSDAKVAMWGYSGGSLASGWAAALQPKYAPELKKNLIGAALGGFVTNITATAEATDGTLFAGLVPNALSGLANEYPEFKEILYQKVSKAATDNLRQGTEHCIGGAILYFAEDQYFTGDDRAFPGGYGLLKEEVVNKTISENNLMQMDKDYLPDIPIFVYHGALDSIVPISNVHVTYKNWCDWGINSFEFSEDLLNGHITETIVGAPAAITWLEARFDGEPVVKGCKKTSRITNFSYPNISDSTSSIFEGILNSVTGSELGPGVTSDNITLDGLTGFLGNFIDLK", "length": 468, "molWeight": 50811, "crc64": "4FF3C05A948B14DA", "md5": "720D96907BAD99B7A211CC6AF2CA2C12"}}
{"primaryAccession": "O94278", "text": "This is Thiamine repressible genes regulatory protein thi5 protein, from Fission yeast, contains 857 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94278", "organism_name": "Fission yeast", "protein_name": "Thiamine repressible genes regulatory protein thi5", "length": 857, "firstPublicDate": "2008-09-23", "FUNCTION": "Transcription factor that activates the nmt1 promoter, Regulation of thiamine repressible genes, Negatively regulates conjugation during meiosis, by inducing negative regulators which delay conjugation, Involved in thi1 regulation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MCPSDFSSRSLFLEAKEEEYKQRRRVPLDSRRRVRRACLSCRAKKIRCSGSEPCQACIATPSQCKYADSLKERTPSKQFIAELSQRQKCFEYLMELLCPSLPHDTRSLVKLCKHVESSLASGSDVRSLLIPGSIDQSVLKVAATNNKDDSSAVKSANVSFPSSSTPPSSDSNFSSIQNTDLNTSIKFTENISANAIHVNQDKVIRSANNLIINSQPILPVRSFLDALGEPIYLSPTSSTYFLNSVLASLQLNSSNTPESLLIDYQSKIPEDLSSSLLPLELNTLQSTPTSVSVGSASSQGTHEYSIINLTSNHSSFSLKALKKIAHNLLPPVSVAERYANEFFLRYQSFFYFYPPSVFSNRYQILADGLVNSDTLDTGFLAVALLIVVLGHFSNNNINVLPKEVQLSHIDSMIQISEQLISSLLNRCTLSSIQAVFLLSLYHFLTGNFKCAYSYLGFAIHSAHTLGLEHGSTDNSTLNEVSTEETSIRICWSLRVLASFLYIQSGITPIINLFPNGLNSLKLPTVVPELEARHLPSSVFHFVAIIKYAEISVRSLNSLYESSSDYLMDVSNFPKLLLKVERIYSQARNWKLNLTHQQLNGTNDTSDLLFHSNVSLHLFYHYLIVKVSCPIMFFYLNNWYSVKPSSFTKGLNNKPSLEDVFSNLETCYESAKAIVQLSSKLLSAGQMDKCFYLEFEILYCSAIVLFLFSVMHLGAENPLLESIYLLEDMGSRTIDSKVRLEKLKSAIEIFDINSATEMPINEPLSASFESVNKENSQSGYMAWQNWVTELSSSNIPLGHALGNPESNNSSNSFKPSHPSQSFLVNESLDFSSNPKEPPFLPWSEALLNMDMQLNRLGP", "length": 857, "molWeight": 95579, "crc64": "5D74EEC81CD74A73", "md5": "06E955AE9745E2461C8346E31F94EFD9"}}
{"primaryAccession": "O94330", "text": "This is Amino-acid acetyltransferase, mitochondrial protein, from Fission yeast, contains 500 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94330", "organism_name": "Fission yeast", "protein_name": "Amino-acid acetyltransferase, mitochondrial", "length": 500, "firstPublicDate": "2009-05-05", "FUNCTION": "N-acetylglutamate synthase involved in arginine biosynthesis", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the acetyltransferase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQKPSLSQDLIWILKSVQSRRSTKGFLQKHSSLKDGSPNKKSFAQPISSSFLNRISITKIDDVDSLSDNTLYGIGRSINSLARLGIQSVIVPTSNPIGMTSPFKYLENGTVVAKKRKLSIFEELQQQQNRVIRVSEIFSKAGVLTRPSYSSVCQLGPEGPSVENVQGIFQALSSLYTVIVPSSILMPNVIEVPIDGNEVLAGLTYSLHKPNFGFWVDRIVILDKNGGMPCSKRQTGSSHVLINLAQEFDELAKTLPPYHRKNLILVRRCLKMLPDDASALITTPEDAMLTNPVLDKNPLIHNVLTDRSIISCSLPRDRSPITKTTVLRSGVPVYTFLGPKCLTDGSVSWERLWVLINDSFKRTLDMDAYLDRLKNSLAAVIIAGDYLGTAIVTYEQPDGTTNEKVPYLDKLAVSQGAQGSAAISDVMFNVMTDLFPKELIWRSRLTNPVNKWYFERSVGSLKSSKTPWKLFWTGDSHVRNLDRVNQYMSVIDKIQPTWLN", "length": 500, "molWeight": 55777, "crc64": "97FD57788EF4E451", "md5": "F8C949845FD8AD8143C43AE15966B5DF"}}
{"primaryAccession": "O94438", "text": "This is Small ribosomal subunit protein eS1B protein, from Fission yeast, contains 252 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94438", "organism_name": "Fission yeast", "protein_name": "Small ribosomal subunit protein eS1B", "length": 252, "firstPublicDate": "2002-03-05", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAVGKNKRLSKGKKGIKKRVVDPFSRKEWYDIKAPAFFEVKNVGKTLVNRTAGLKNANDSLKGRILEVSLADLQKDEEHAFRKVKLRVEDIQGKSCLTSFNGLSITSDKLRSLVRKWQTTIEADQTIKTTDGYLCRVFVIGFTRRRANQVKKTTYAQSSQIRAIRQKMFQVIQNQTSSCSMRELVQKLIPEVIGREIERATGSIFPLQNVLVRKVKILKAPKHDAQKLLELHGESQDVGTKVVKDVAPLESV", "length": 252, "molWeight": 28521, "crc64": "29D08AA6BB3ACFF8", "md5": "7C955034059711D12C3AAF132295F4C5"}}
{"primaryAccession": "O94439", "text": "This is FAS1 domain-containing protein fsc1 protein, from Fission yeast, contains 728 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94439", "organism_name": "Fission yeast", "protein_name": "FAS1 domain-containing protein fsc1", "length": 728, "firstPublicDate": "2008-12-16", "FUNCTION": "Required for the fusion of autophagosomes with the vacuole", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNLQFRLYLLFILLFISFANGKNEYEDKSTSIIDLLSSKSQFSKLIRRLQRNRLVPYLNRNKGLTLFAPLNEAFPDDSIEPNLLYYIVNTTELDRSVLRTQLKSSDGQQIALKIHYKAETGRAYDKVNNAQIVQSNWRADSGVVQVIDNIIDLPPPALEILSSEKDFSIFHRLSVAWVGEYSSVTMLVPDSSAFLNVYTNTELAYLYSMYAAEDVKTLIHQHILVNQRVYAEDVIEPKTFHYKNGISISMKFDKDQKKLFINDVSTTKYDLLTFSGAIHTVSSLINPEIISFTPAKYLIGIGAAWFSEKLSRERKSISVDKTSKRAILAPTNWAYREIIDIDYHIIENFDLPAPNKYALYVTNIKSGNSVGEDTNALVRIATGSAGEMYVNVETRSIQSENIGNVSLYVLDKDIEPPQPLLSQLILVDEISFSVRYLASLGLGDYTKVTWFLVKNSAWTQLGLVHLVLQQNLELLESVMLDYAFEGIAFYGSSDEAWASGNYTTLSNKEFLIEGVYEDSNSRNKRDLLRINNEIYEVQTRDLLVKDGVVHLVDKVKLPFSVSQKDMIIAGGRKEFLELLDKFEMLDMLDSGYPVVVPSLTGSDVNTKDSSFAERHIIDPEKRNFVISGSRLSVDSSPWISIQDYGYSELGNVYFVQNAIPTKRQNRWRITFISISGLLLSVGICVLCYKIYFKFFRNRFMNQGEREPLLAPADSDTMAGRRNSSSLSV", "length": 728, "molWeight": 82589, "crc64": "ADF34622B35463C7", "md5": "33000F6B8EA5F6E999F58BF3AC7AB2E2"}}
{"primaryAccession": "O94527", "text": "This is WD repeat protein iqw1 protein, from Fission yeast, contains 809 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94527", "organism_name": "Fission yeast", "protein_name": "WD repeat protein iqw1", "length": 809, "firstPublicDate": "2008-02-05", "FUNCTION": "Ligand-dependent coactivator of nuclear receptors that may function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSGISLSLRQLDYRDWFQRKISRDIYGNSTWLTGIDLQKELTGHTGCVNTLDWSADGEFLLSGSDDTRLIVWDVFNEYKPRHLISTGHVQNIFSAKFVPYSNNRQILSASGDKLIKLFDLDSSKEGGMDHGMETQTRCWSCALDSVKNIVPCDNGHTFLVCSEDGTARQYDIREPHVCNQDLDCPSILVNYNPYRINLYTITMSPSNPYYFAIGGTHPYAFLYDRRMVKKSFRDDWTMNTSPEKDCRCVRKFSPDGSCNSQGILDRYITCCQFSAANPNELLVSWNSDYVYLFHVHEDKSYTPTFNKIEDSNKKPSKPSLLQTQPLKRKNYSPWYKNNFGASTPASRVSRNPYTAAQPRKHTFYQMYENIEKFFTTENGGLYESIVSGRLSHFSRSIQYVKDAIYFLENYNYIPDSNGLNHSIRVSALRYWRACVSILALMDDTVSLEPNTIIQAGWGWLYDFMNWVTRYLLGISDHWALQMSPPTNVARQNFVLCDPDEPSRVLFSNPSEMIRAFARIDTNDLSSVRRFFWIHKVLRGCLLLISSDIYWEQFQPWDSSTSDVTSSQRLDDENGFLTLLEPPVNYENEVESSSGENIVSMYTGHSDLNDDDDDYQDEESYSYASDDDDESDEDSDEGPTLLSLRMKKRKAVEPNVPVNTHVKSYYGHCNVESIKNVNFYGQNDEYVMSGSDDGRFFIWDKLNASILAIIHGDSEAVNVIEGHPRCPTLAVSGIDSTVKIFNTENTPPSGCSRNHTSNSYKIIATNEMNRQQGSRDSYITSRMLSHLAYRAHLDDGFGHEVLDTDACSIM", "length": 809, "molWeight": 92499, "crc64": "4877443546BD057E", "md5": "9DE4112BC6F3755C2AB8C3C4959EB4A7"}}
{"primaryAccession": "O94566", "text": "This is Meiotically up-regulated gene 184 protein protein, from Fission yeast, contains 551 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94566", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 184 protein", "length": 551, "firstPublicDate": "2007-02-20", "FUNCTION": "Has a role in sporulation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLARPETDTSVDYYAILKLQKNATFQQIRKQYLFLALQYHPDRNPGDEERAVKRFQRLQLAHEVLSDATKRLIYDQLFGLSTRTRSQYKPNSTSNPSKHTSAYASYNKGKNSKWSSPFASTTKKPQESSEKYSKKSSTRKKEHFNKKPSFPRDTEYSHIYNMKYDPRSGIGIRVKRQEPESLKKENNNSDYLPKSAMKQKKGGPKDSSKHPSNDGKIPESKPSVYKSRASNLFSSNEQSIHSSFGSKFHFDKSSNPFSFEFSPSSNAAKPSNSEECNIPKFNSSFKTSNDFFTFTKTEESSPYSFSFKLEDSNTPKFKSSSKPVKSSFVFTKPEAESSNPFSFDFGSSGPKSRSDTRNNIRTPLWTSSVFEKPESDLPNKTAFGFMRSNTSTFNQKCDDFSSASFMKEKTEFEEQLQEDNDHSLGDLFSKINISTESPSVAMPSIPVIQPPSFPIFSSIDFNVRNREYWNQLMVFQKLYSKYCTESQHFINSWINIKKELHIVPVNWEIFEKVEKSWDQCEEFVAEFRQTEEKYFLFLKRLRELINKNQML", "length": 551, "molWeight": 63758, "crc64": "772C5416E3C0B764", "md5": "86F9F40F1A266C9C830B61504E080549"}}
{"primaryAccession": "O94598", "text": "This is Exocyst complex component sec5 protein, from Fission yeast, contains 815 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94598", "organism_name": "Fission yeast", "protein_name": "Exocyst complex component sec5", "length": 815, "firstPublicDate": "2009-05-05", "FUNCTION": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the SEC5 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSADEEILAHYGLTSLSQDYWTEKPDFAIANASVDVQSPTTGVHHERNRSEDILRTGGATSETTKDASAAGPVTPSFAMKRSQTSVQPSMSSQIAIGGMRNPMATRKIAGTYRDAPDNSMQQTSTGVHRSSSWLTTDGTHQLLSLMETNFNKFIAAKETIDNVYAQIISTLSHAGPAKTMDMCEESISGALQQLQLFNTESTNEVDISYGELLVMRECEALFTYPEKFRLYHKQEKYSLLMQEIENAKKLYEKDRERLAKVNPKLVYLVDHAWEIIQATIDGICASIWNQILQSQGDFAFVVRTLCDLLKLKPNPISGRDPVLYATVSQQKYLYNLMKERFSYFEKIIKSRQEDFSKLSCTRASPMLVWRAVARGCNLDYTLRGRPEVFAGMQLIEWANACVLKIVREIKEVELYAKEFISGIQQASYPEAAKHYGRDPKQMGVVVEKLNSQCLEMVYSFVGERGERLEMDGAFVLIQLHYFQRVADLLPKRIRTVFSMAATRCIVDTWMLQHAPQSKSANIEEMFIVDANENQVLEPELMVVDVLRELNKLYIPPHREEIVREIHHAFYKVLYANARFPSMSVSMANWESDVWSLASSTLIDFVQHRNQHDMKKLASKMTTSLPVFSTSITRSDVLHFVTRLLNLRSRLVPYQKFLLQTFPLNEVSPSLDPRISKSLRNLQDLYKLLAIRDTSFSNTTPSSISKLSIQPPTFQLFSTLETIYLELKDSMPPNEAADWMIATTSCMLAQFALHSPYAFFHDIPSISHFLNKCLPPTILDLLQQIQRKAEASSISPTTETATKTRLKFQFIEMIFS", "length": 815, "molWeight": 92711, "crc64": "A5A54C79401CF69B", "md5": "2112D2B0FA47D61DEA61C2E1638141B0"}}
{"primaryAccession": "O94704", "text": "This is INO80 complex subunit 3 protein, from Fission yeast, contains 168 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94704", "organism_name": "Fission yeast", "protein_name": "INO80 complex subunit 3", "length": 168, "firstPublicDate": "2007-09-11", "FUNCTION": "Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASVKSFKRKYLKLRKSFDSVVLETEEIEQKIAEISEVYRRILLENAHLNDLLIDMNSTVLPTPPASPPGSPYWEAKPVSHTVFLESPSDVFTLEKPIASTHRWLSKLTALSKSTNSTLSTPKSFHSPLQSRGISPSSAQSSAAVSSSRKQKRKRTSEGPSERRARKK", "length": 168, "molWeight": 18765, "crc64": "EE5C894F815879CF", "md5": "38BC8689CC8FBA5ED3B29D72BFA1FDBD"}}
{"primaryAccession": "O94745", "text": "This is Probable mitochondrial-processing peptidase subunit alpha protein, from Fission yeast, contains 502 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94745", "organism_name": "Fission yeast", "protein_name": "Probable mitochondrial-processing peptidase subunit alpha", "length": 502, "firstPublicDate": "2003-04-11", "FUNCTION": "Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the peptidase M16 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSFLTTPKMLSEYQCLKNIGFSHKTVLKRRLFRKECTPALKSFYSTQDPALNEVRTEKLKNGVTYVCDPRPGHFSGLGVYVKAGSRYETKKFSGVSHFMDRLAFQATERTPVGEMKAKLENLGGNYMCSTSRESMIYQAAVFNDDVKSMSKLLAETVLAPKIQEDDLVHYRDSIIYENSELWTKPDALLGEFAHVTAFQNNTLGNCLLCTPDKVNGITATSIREYLKYFYRPEHLTLAYAGIPQEIAKEITKELYGHLPSSSLPPLEAIPSHYTGGFMGIKKSEAPPVPYQQEFTHVVIAMEGLPVTDPDIYALACLQFLLGGGGSFSAGGPGKGMYSRLYLNVLNQYPWVETCMAFNHSYTDSGLFGMFVTILDDAAHLAAPLIIRELCNTVLSVTSEETERAKNQLKSSLLMNLESRMISLEDLGRQIQTQNGLYITPKEMIEKIDALTPSDLSRVARRVLTGNVSNPGNGTGKPTVLIHGNVDEVGDVFALCKKAGIGH", "length": 502, "molWeight": 55578, "crc64": "8543230258A6A16C", "md5": "9DF03EC4AAE945AC9FDAEFF8AF0B9175"}}
{"primaryAccession": "P00287", "text": "This is Plastocyanin protein, from Kidney bean, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00287", "organism_name": "Kidney bean", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "LEVLLGSGDGSLVFVPSEFSVPSGEKIVFKNNAGFPHNVVFDEDEIPAGVDAVKISMPEEELLNAPGETYVVTLDTKGTYSFYCSPHQGAGMVGKVTVN", "length": 99, "molWeight": 10492, "crc64": "D529B771D87BDBB9", "md5": "21CCBDA6BA197732AC2142BF8E765219"}}
{"primaryAccession": "P00289", "text": "This is Plastocyanin, chloroplastic protein, from Spinach, contains 168 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00289", "organism_name": "Spinach", "protein_name": "Plastocyanin, chloroplastic", "length": 168, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATVASSAAVAVPSFTGLKASGSIKPTTAKIIPTTTAVPRLSVKASLKNVGAAVVATAAAGLLAGNAMAVEVLLGGGDGSLAFLPGDFSVASGEEIVFKNNAGFPHNVVFDEDEIPSGVDAAKISMSEEDLLNAPGETYKVTLTEKGTYKFYCSPHQGAGMVGKVTVN", "length": 168, "molWeight": 16917, "crc64": "F9AAA77D7EFCDBE0", "md5": "441F3191323D87716987A80C51482BC7"}}
{"primaryAccession": "P00299", "text": "This is Plastocyanin A, chloroplastic protein, from Lombardy poplar, contains 168 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00299", "organism_name": "Lombardy poplar", "protein_name": "Plastocyanin A, chloroplastic", "length": 168, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATVTSAAVSIPSFTGLKAGSASNAKVSASAKVSASPLPRLSIKASMKDVGAAVVATAASAMIASNAMAIDVLLGADDGSLAFVPSEFSISPGEKIVFKNNAGFPHNIVFDEDSIPSGVDASKISMSEEDLLNAKGETFEVALSNKGEYSFYCSPHQGAGMVGKVTVN", "length": 168, "molWeight": 17020, "crc64": "901B21A7573DBF82", "md5": "90010837E78933EE40CEAAAE9F56A639"}}
{"primaryAccession": "P00732", "text": "This is Carboxypeptidase B protein, from Bovine, contains 417 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00732", "organism_name": "Bovine", "protein_name": "Carboxypeptidase B", "length": 417, "firstPublicDate": "1986-07-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase M14 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLAFLILVTVTLASAHHSGEHFEGDKVFRVHVEDENHISLLHELASTRQMDFWKPDSVTQVKPHSTVDFRVKAEDTVAVEDFLGQNGLRYEVLISNLRSMLEAQFDSRVRTTGHSYEKYNNWETIEAWTEQVASENPDLISRSAIGTTFLGNTIYLLKVGKPGSNKPAVFMDCGFHAREWISPAFCQWFVREAVRTYGREIHMTEFLDKLDFYVLPVVNIDGYIYTWTTNRMWRKTRSTRAGSSCTGTDLNRNFDAGWCSIGASNNPCSETYCGSAAESEKESKAVADFIRNHLSSIKAYLTIHSYSQMMLYPYSYDYKLPKNNVELNTLAKGAVKKLASLHGTTYTYGPGASTIYPASGGSDDWAYDQGIKYSFTFELRDKGRYGFVLPESQIQPTCEETMLAIKYVTSYVLEHLY", "length": 417, "molWeight": 47348, "crc64": "923DABC54214CB27", "md5": "A6D68F60C4B5EB4AF3805989440340F9"}}
{"primaryAccession": "P04814", "text": "This is Trypsin alpha protein, from Fruit fly, contains 256 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P04814", "organism_name": "Fruit fly", "protein_name": "Trypsin alpha", "length": 256, "firstPublicDate": "1987-08-13", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLKIVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAAASGKDACQGDSGGPLVSGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWVVSTANSI", "length": 256, "molWeight": 26041, "crc64": "8B5634992F2E7C63", "md5": "D5DB5668E0324B939C93452E728CCD4D"}}
{"primaryAccession": "P07030", "text": "This is Plastocyanin, chloroplastic protein, from White campion, contains 165 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P07030", "organism_name": "White campion", "protein_name": "Plastocyanin, chloroplastic", "length": 165, "firstPublicDate": "1988-04-01", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MATVTSSAAVAIPSFAGLKASSTTRAATVKVAVATPRMSIKASLKDVGVVVAATAAAGILAGNAMAAEVLLGSSDGGLAFVPSDLSIASGEKITFKNNAGFPHNVVFDEDEVPAGVDVTKISMPEEDLLNAPGEEYSVTLTEKGTYKFYCAPHAGAGMVGKVTVN", "length": 165, "molWeight": 16620, "crc64": "C4F817E69BC514A0", "md5": "038D2F575C9132CE7D4B23046AD91018"}}
{"primaryAccession": "P09932", "text": "This is Homothallic switching endonuclease protein, from Baker's yeast, contains 586 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P09932", "organism_name": "Baker's yeast", "protein_name": "Homothallic switching endonuclease", "length": 586, "firstPublicDate": "1989-07-01", "FUNCTION": "Initiation of mating type interconversion, This protein is a site-specific endonuclease that cleaves a site in the mat locus on chromosome III, The double-strand break is followed by a unidirectional gene conversion event that replaces the information at the mat locus by information copied from either of the two homologous loci (HMR and HML) that reside at the extremity of the chromosome III, Endonuclease expression takes place in late G1 just before cells enter S phase", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLSENTTILMANGEIKDIANVTANSYVMCADGSAARVINVTQGYQKIYNIQQKTKHRAFEGEPGRLDPRRRTVYQRLALQCTAGHKLSVRVPTKPLLEKSGRNATKYKVRWRNLQQCQTLDGRIIIIPKNHHKTFPMTVEGEFAAKRFIEEMERSKGEYFNFDIEVRDLDYLDAQLRISSCIRFGPVLAGNGVLSKFLTGRSDLVTPAVKSMAWMLGLWLGDSTTKEPEISVDSLDPKLMESLRENAKIWGLYLTVCDDHVPLRAKHVRLHYGDGPDENRKTRNLRKNNPFWKAVTILKFKRDLDGEKQIPEFMYGEHIEVREAFLAGLIDSDGYVVKKGEGPESYKIAIQTVYSSIMDGIVHISRSLGMSATVTTRSAREEIIEGRKVQCQFTYDCNVAGGTTSQNVLSYCRSGHKTREVPPIIKREPVYFSFTDDFQGESTVYGLTIEGHKNFLLGNKIEVKSCRGCCVGEQLKISQKKNLKHCVACPRKGIKYFYKDWSGKNRVCARCYGRYKFSGHHCINCKYVPEAREVKKAKDKGEKLGITPEGLPVKGPECIKCGGILQFDAVRGPHKSCGNNAGARIC", "length": 586, "molWeight": 66089, "crc64": "95771394D177823A", "md5": "957A3548EFBC5B1BCEDF408292543B07"}}
{"primaryAccession": "P0C1Y9", "text": "This is Fasciculin-1 protein, from Eastern green mamba, contains 61 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C1Y9", "organism_name": "Eastern green mamba", "protein_name": "Fasciculin-1", "length": 61, "firstPublicDate": "2006-10-17", "FUNCTION": "Interferes with neuromuscular transmission by inhibiting the enzyme acetylcholinesterase (AChE) present at the neuromuscular junction, It selectively binds and inhibits with a 1:1 stoichiometry the mammalian and electric fish AChE at picomolar concentrations, It is highly specific for the peripheral site of AChE and blocks the entry of acetylcholine into the active site of the enzyme, thereby preventing its breakdown, It has been called fasciculin since after injection into mice it causes severe, generalized and long-lasting (5-7 hours) fasciculations", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the snake three-finger toxin family, Short-chain subfamily, Acn-esterase inhibitor sub-subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDYLEVKCCTSPDKCNY", "length": 61, "molWeight": 6807, "crc64": "50A38EF3633C2AB4", "md5": "7C2994B83C8ED1AC4AD790381F6AEA9E"}}
{"primaryAccession": "P0C2B6", "text": "This is Large ribosomal subunit protein mL51 protein, from Bovine, contains 128 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C2B6", "organism_name": "Bovine", "protein_name": "Large ribosomal subunit protein mL51", "length": 128, "firstPublicDate": "2007-01-23", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mL51 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGSLSWVAGRRLWGLVPLACRSFFLGVPRLFHVRVTLPPPKVIDRWNQKRAMFGVYDNIGILGNFEKHPKELIKGPVWLRGWKGNELQRCIRKKRMVGNRMFIDDLHNLNKRISFLYKRFNRHGKHR", "length": 128, "molWeight": 15162, "crc64": "AB714A2A7F7C2D2D", "md5": "57CD6030D3D7079A84AF6C9AF28BDBB7"}}
{"primaryAccession": "P0C607", "text": "This is Conotoxin ar11a protein, from Sand-dusted cone, contains 75 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0C607", "organism_name": "Sand-dusted cone", "protein_name": "Conotoxin ar11a", "length": 75, "firstPublicDate": "2008-01-15", "FUNCTION": "Both natural (L-Leu form) and synthetic (D-Leu from) peptides equally cause sensitivity to touch and body tremor, Neither L-Leu form nor D-Leu form is active on nerve-muscle preparation", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the conotoxin I1 superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLCATFLLVLVTLPLVTGEKSSERSLSGAILRGVRRTCSRRGHRCIRDSQCCGGMCCQGNRCFVAIRRCFHLPF", "length": 75, "molWeight": 8377, "crc64": "93AD875E576F8EB4", "md5": "89CE71D093E86484C9FDB037E2B05069"}}
{"primaryAccession": "P0CG12", "text": "This is Decreased expression in renal and prostate cancer protein protein, from Human, contains 524 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CG12", "organism_name": "Human", "protein_name": "Decreased expression in renal and prostate cancer protein", "length": 524, "firstPublicDate": "2010-06-15", "FUNCTION": "Potential tumor suppressor, Inhibits prostate tumor cell growth, when overexpressed", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the DERPC family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKEPRIFPRERPTPWTRAPLPPRGRLDGSLGPQGGPVLNTGHPLGVNSDPFLMAAGSLGGNLTPFPRNPSPFPASSGSLASNPAPFPAGARDPSMASFPRGMNPTGTGAVSFPRPGGLLGPGPGPGPTLNPRTGALPGPGPLSNPRLGGLPGPGPMSNPRAGGLLGAGPDPRGGGPMGPGSGPNLRAGVLLTSGNGPPNPRPVGLGPGPNPNLRSGFLGTNPAPRSGVFPGPGLGPNPRPSGLGPGPNLDARAGGLLGTGSGLNLRMAGPQGLDLAPILRAAGLLGANSASFSQASGNMGTSPSSMARVPGPMGPNSGPSSRGIGLPGPNPSPMSRAPGPIGPNSAHFSRPVGPMGVNANPFPRGAGSSAFSQSSGTLASNPATFQRSAGLQGSNPTIFPRASGPLGPNPANFPRATGLQGPSPTTFPRSTGPLGPGQVTFPRPAAGHLGPSPAGPVGINPAPFTRPTGTLGLNPASFPRMNGPAGKSFVPFPRVGSLPGTNPAAFPRPGGPMAAMYPNGMLPP", "length": 524, "molWeight": 51391, "crc64": "C917FEEC7BC3702E", "md5": "BFBD1AFF265FD4C91B297DA2B022DFFE"}}
{"primaryAccession": "P0DL48", "text": "This is Omega-agatoxin-Aa5a protein, from North American funnel-web spider, contains 48 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0DL48", "organism_name": "North American funnel-web spider", "protein_name": "Omega-agatoxin-Aa5a", "length": 48, "firstPublicDate": "2015-06-24", "FUNCTION": "The toxin blocks voltage-gated calcium channels in rat cerebellar granule cells (IC(50)=200 nM)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 02 (plectoxin) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "EACAGAYKSCDKVKCCHDRRCRCNIAMDNCVCKLFYCELFGTCDRLKP", "length": 48, "molWeight": 5485, "crc64": "7DF62D82967018E8", "md5": "4174F2C259175F71B2A6C6EDBDED7538"}}
{"primaryAccession": "P11970", "text": "This is Plastocyanin B, chloroplastic protein, from Lombardy poplar, contains 168 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P11970", "organism_name": "Lombardy poplar", "protein_name": "Plastocyanin B, chloroplastic", "length": 168, "firstPublicDate": "1989-10-01", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAAVTSAAVSIPSFTGLKAASASNAKVSASAKVSASPLPRLSIKASLKEVGAAVVATAASAMIASNAMAVDVLLGADDGSLAFVPSEFSVPAGEKIVFKNNAGFPHNVLFDEDAVPSGVDVSKISMSEEDLLNAKGETFEVALSDKGEYTFYCSPHQGAGMVGKVIVN", "length": 168, "molWeight": 16981, "crc64": "F20DA6EA2038AEEA", "md5": "B98ABBEA71339D00EAF1A39FEDBBBF33"}}
{"primaryAccession": "P12353", "text": "This is Photosystem I reaction center subunit II, chloroplastic protein, from Spinach, contains 212 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P12353", "organism_name": "Spinach", "protein_name": "Photosystem I reaction center subunit II, chloroplastic", "length": 212, "firstPublicDate": "1989-10-01", "FUNCTION": "PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center, PSAD may encode the ferredoxin-docking protein", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the PsaD family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAMATQATLFSPSSLSSAKPIDTRLTTSFKQPSAVTFASKPASRHHSIRAAAAAEGKAAAATETKEAPKGFTPPELDPNTPSPIFAGSTGGLLRKAQVEEFYVITWESPKEQIFEMPTGGAAIMREGPNLLKLARKEQCLALGTRLRSKYKIKYQFYRVFPSGEVQYLHPKDGVYPEKVNPGRQGVGLNMRSIGKNVSPIEVKFTGKQPYDL", "length": 212, "molWeight": 23103, "crc64": "BC5FF64D97A6570E", "md5": "9BF52C2A60C41841C24E52299F341D3A"}}
{"primaryAccession": "P17341", "text": "This is Plastocyanin A/B protein, from Parsley, contains 97 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P17341", "organism_name": "Parsley", "protein_name": "Plastocyanin A/B", "length": 97, "firstPublicDate": "1990-08-01", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "AEVKLGSDDGGLVFSPSSFTVAAGEKITFKNNAGFPHNIVFDEDEVPAGVNAEKISQPEYLNGAGETYEVTLTEKGTYKFYCEPHAGAGMKGEVTVN", "length": 97, "molWeight": 10290, "crc64": "13B76E4BA5AB54DF", "md5": "C2FB520438584845591B2CBBBB3D6D46"}}
{"primaryAccession": "P17558", "text": "This is Small ribosomal subunit protein mS26 protein, from Baker's yeast, contains 318 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P17558", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein mS26", "length": 318, "firstPublicDate": "1990-08-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mS26 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGKGAAKYGFKSGVFPTTRSILKSPTTKQTDIINKVKSPKPKGVLGIGYAKGVKHPKGSHRLSPKVNFIDVDNLIAKTVAEPQSIKSSNGSAQKVRLQKAELRRKFLIEAFRKEEARLLHKHEYLQKRTKELEKAKELELEKLNKEKSSDLTIMTLDKMMSQPLLRNRSPEESELLKLKRNYNRSLLNFQAHKKKLNELLNLYHVANEFIVTESQLLKKIDKVFNDETEEFTDAYDVTSNFTQFGNRKLLLSGNTTLQTQINNAIMGSLSNEKFFDISLVDSYLNKDLKNISNKIDSKLNPTSNGAGNNGNNNNTTNL", "length": 318, "molWeight": 35998, "crc64": "AC1667FD35B0077B", "md5": "E8D87F6AFE59441C38AFB135B8A43435"}}
{"primaryAccession": "P18153", "text": "This is 37 kDa salivary gland allergen Aed a 2 protein, from Yellowfever mosquito, contains 321 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P18153", "organism_name": "Yellowfever mosquito", "protein_name": "37 kDa salivary gland allergen Aed a 2", "length": 321, "firstPublicDate": "1990-11-01", "FUNCTION": "Thought to be involved in blood-feeding", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLPLLLAIVTTFSVVASTGPFDPEEMLFTFTRCMEDNLEDGPNRLPMLAKWKEWINEPVDSPATQCFGKCVLVRTGLYDPVAQKFDASVIQEQFKAYPSLGEKSKVEAYANAVQQLPSTNNDCAAVFKAYDPVHKAHKDTSKNLFHGNKELTKGLYEKLGKDIRQKKQSYFEFCENKYYPAGSDKRQQLCKIRQYTVLDDALFKEHTDCVMKGIRYITKNNELDAEEVKRDFMQVNKDTKALEKVLNDCKSKEPSNAGEKSWHYYKCLVESSVKDDFKEAFDYREVRSQIYAFNLPKKQVYSKPAVQSQVMEIDGKQCPQ", "length": 321, "molWeight": 36895, "crc64": "9BAF0F0335B93070", "md5": "B0DA363B3996CDD762FB8C88C26D048E"}}
{"primaryAccession": "P21750", "text": "This is Protein spalt-accessory protein, from Fruit fly, contains 142 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P21750", "organism_name": "Fruit fly", "protein_name": "Protein spalt-accessory", "length": 142, "firstPublicDate": "1991-05-01", "FUNCTION": "Likely to be involved in the establishment of the head", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLLIALFALVTAVNAQNGFGQVGQGGYGGQGGFGGFGGIGGQAGFGGQIGFTGQGGVGGQVGIGQGGVHPGQGGFAGQGSPNQYQPGYGSPVGSGHFHGTNPVESGHFHENPHEYPEHHGDHHREHHEHHGHHEHHGHHRH", "length": 142, "molWeight": 14555, "crc64": "7DC7C6D210309A87", "md5": "040D12056871404D3FBDBE2229B7C9D7"}}
{"primaryAccession": "P23604", "text": "This is Achelase-1 protein, from Giant silkworm moth, contains 213 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P23604", "organism_name": "Giant silkworm moth", "protein_name": "Achelase-1", "length": 213, "firstPublicDate": "1991-11-01", "FUNCTION": "Fibrinolytic activity; shows preferential cleavage of Arg-Gly bonds in all three fibrinogen chains, Contact with the caterpillars causes severe bleeding, due the anticoagulant effect of the protein", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "IVGGSVTTIGQYPSMASLLFNNRQVCGGVIINNRSVLTAAHCPFGDAVSSWRFRVGSTNANSGGTVFTLSTIINHPSYNRWTLDNDISIMRAASNIGTSASVQPAGIAGSNYNLGDNQVVWATGWGATSAGGSLARFPGVNARHVQIWTVNQNTCASRYAAIGRTVTANMLCSGWLDVGGRDQCQGDSGGPLYHNRIVVAVVSRYTSWIQSNA", "length": 213, "molWeight": 22472, "crc64": "21DD6769C9466542", "md5": "1F2BE5CF1B8E9B8A54E0CDC43AAF022F"}}
{"primaryAccession": "P23605", "text": "This is Achelase-2 protein, from Giant silkworm moth, contains 214 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P23605", "organism_name": "Giant silkworm moth", "protein_name": "Achelase-2", "length": 214, "firstPublicDate": "1991-11-01", "FUNCTION": "Fibrinolytic activity; shows preferential cleavage of Arg-Gly bonds in all three fibrinogen chains, Contact with the caterpillars causes severe bleeding, due the anticoagulant effect of the protein", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "IVGGSTTTIASYPEITALLYFNRQACGGTILNNRSVLTAAHCPFGDAASSWSFRVGSTNANSGGTVHSLSTFIIHPSYNRWTLDNDIAIMRTASNINFINNAVRPGSIAGANYNLADNQVVWAAGWGTTSPGGSLARFPGVNARHVQIWTVNQATCRTRYASIGHTVTDNMLCSGWLDVGGRDQCQGDSGGPLYHNGVVVGVVSRYTAWIQSNA", "length": 214, "molWeight": 22726, "crc64": "71CF4823DDFE32E8", "md5": "0E795BCAE5515FC87F6368AB9856CD21"}}
{"primaryAccession": "P23757", "text": "This is Paired box pox-meso protein protein, from Fruit fly, contains 370 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P23757", "organism_name": "Fruit fly", "protein_name": "Paired box pox-meso protein", "length": 370, "firstPublicDate": "1991-11-01", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDPESQCPQYGEVNQLGGVFVNGRPLPNATRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSILPGAIGGSKPRVTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVPSVSSISRILRNKLGSLGHQHTPGTVMGSGSSSGGGSVSSNGGQNNGTSASNNINLSNLGNPGGGPHHPHHHHHHQSAAAAASAHHVHAHAHAHAHLYNSIYQPYSAAAAYSMKTPCGSPSPPQGAGGQGSVPHPHQLRSVAAAAAAAHWPSSHSVSDILAHHQAVALRASCQVGVGVGGMGGMGSTVSPLPMTPSPVAGTAGGQPLLDCEGGAGQQSPYNYYMYFQNGGMHHHHHHGGMMAAGATGL", "length": 370, "molWeight": 38388, "crc64": "73932D0001019C32", "md5": "7E9987FCB47A06F47E9B288F94EF0AF0"}}
{"primaryAccession": "P25684", "text": "This is Toxin C10S2C2 protein, from Eastern green mamba, contains 60 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25684", "organism_name": "Eastern green mamba", "protein_name": "Toxin C10S2C2", "length": 60, "firstPublicDate": "1992-05-01", "FUNCTION": "This specific blocker of the L-type calcium channel (Cav1/CACNA1) is a smooth muscle relaxant and an inhibitor of cardiac contractions", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the snake three-finger toxin family, Short-chain subfamily, L-type calcium blocker sub-subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "RICYSHKASLPRATKTCVENSCYKMFIRTSPDYISDRGCGCPTAMWPYQTACCKGDRCNK", "length": 60, "molWeight": 6818, "crc64": "C7BAC44373B63CE8", "md5": "E8E5136CF894C06E588E015B93146555"}}
{"primaryAccession": "P30288", "text": "This is Omega-agatoxin-Aa4a protein, from North American funnel-web spider, contains 48 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30288", "organism_name": "North American funnel-web spider", "protein_name": "Omega-agatoxin-Aa4a", "length": 48, "firstPublicDate": "1993-04-01", "FUNCTION": "Omega-agatoxins inhibit neuronal voltage-gated calcium channels, This toxin acts by modifying the gating of the high voltage activated P-type Cav2,1/CACNA1A channel, Is a potent blocker in both insect and mammalian central neurons", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 02 (plectoxin) family, 03 (omega-agtx) subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "KKKCIAKDYGRCKWGGTPCCRGRGCICSIMGTNCECKPRLIMEGLGLA", "length": 48, "molWeight": 5210, "crc64": "945054B55EAE81FD", "md5": "1EAD35A0141ED24887739B555F4B1FC1"}}
{"primaryAccession": "P30292", "text": "This is Alpha-amylase protein, from Aspergillus shirousami, contains 499 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P30292", "organism_name": "Aspergillus shirousami", "protein_name": "Alpha-amylase", "length": 499, "firstPublicDate": "1993-04-01", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 13 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMVAWWSLFLYGLQVAAPALAATPADWRSQSIYFLLTDRFARTDGSTTATCNTADQKYCGGTWQGIIDKLDYIQGMGFTAIWITPVTAQLPQTTAYGDAYHGYWQQDIYSLNENYGTADDLKALSSALHERGMYLMVDVVANHMGYDGAGSSVDYSVFKPFSSQDYFHPFCFIQNYEDQTQVEDCWLGDNTVSLPDLDTTKDVVKNEWYDWVGSLVSNYSIDGLRIDTVKHVQKDFWPGYNKAAGVYCIGEVLDVDPAYTCPYQNVMDGVLNYPIYYPLLNAFKSTSGSMDDLYNMINTVKSDCPDSTLLGTFVENHDNPRFASYTNDIALAKNVAAFIILNDGIPIIYAGQEQHYAGGNDPANREATWLSGYPTDSELYKLIASANAIRNYAISKDTGFVTYKNWPIYKDDTTIAMRKGTDGSQIVTILSNKGASGDSYTLSLSGAGYTAGQQLTEVIGCTTVTVGSDGNVPVPMAGGLPRVLYPTEKLAGSKICSSS", "length": 499, "molWeight": 54852, "crc64": "1FB7AE50DA01C03F", "md5": "F138D7E17E41A4E43F45941EB3F31BE0"}}
{"primaryAccession": "P31272", "text": "This is Homeobox protein Hox-B9 protein, from African clawed frog, contains 232 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P31272", "organism_name": "African clawed frog", "protein_name": "Homeobox protein Hox-B9", "length": 232, "firstPublicDate": "1993-07-01", "FUNCTION": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Abd-B homeobox family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAISGPLTNYFVQSIISPDTDETPAAKFSAQFPNPRAPAQSEPLDFPSCSFSASWNFLTPHPPVYQPYIQQQQQQEEGAPSAEGRYLRAWLDNGPSLKSEPLLGPPGDKLGPQHYTVASPGGAAANTERSTHSGNFPDTKGTEGTAGETDRTHQNNPSANWLHARSSRKKRCPYSKYQTLELEKEFKFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKLNKDQSKD", "length": 232, "molWeight": 26238, "crc64": "F8DC4E6003098857", "md5": "FC8F4B85054CC838E6210D5EEABE5630"}}
{"primaryAccession": "P32902", "text": "This is Small ribosomal subunit protein uS2m protein, from Baker's yeast, contains 394 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P32902", "organism_name": "Baker's yeast", "protein_name": "Small ribosomal subunit protein uS2m", "length": 394, "firstPublicDate": "1993-10-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uS2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQRHVFARNFRRLSLLRNPSLTKRFQSSASGAANTPNNNDEVMLLQQKLLYDEIRSELKSLSQVPEDEILPELKKSLEQDKLSDKEQQLEAELSDFFRNYALLNKLFDSKTLDGQSSTTTAAATPTKPYPNLIPSANDKPYSSQELFLRQLNHSMRTAKLGATISKVYYPHKDIFYPPLPENITVESLMSAGVHLGQSTSLWRSSTQSYIYGEYKGIHIIDLNQTLSYLKRAAKVVEGVSESGGIILFLGTRQGQKRGLEEAAKKTHGYYVSTRWIPGTLTNSTEISGIWEKQEIDSNDNPTERALSPNETSKQVKPDLLVVLNPTENRNALLEAIKSRVPTIAIIDTDSEPSLVTYPIPGNDDSLRSVNFLLGVLARAGQRGLQNRLARNNEK", "length": 394, "molWeight": 44152, "crc64": "81A1CB33134BC559", "md5": "C0C1FD885DF1978619DD382AD1A9D485"}}
{"primaryAccession": "P36029", "text": "This is Polyamine transporter TPO5 protein, from Baker's yeast, contains 618 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36029", "organism_name": "Baker's yeast", "protein_name": "Polyamine transporter TPO5", "length": 618, "firstPublicDate": "1994-06-01", "FUNCTION": "Required for polyamine transport, Transports putrescine effectively and spermidine less effectively", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the amino acid-polyamine-organocation (APC) superfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPEYTLLADNIRENIVHFDPNGLFDNLHTIVHEDDSQENEEAEHFNYDQVLDKSLLSRGSIVGLGLGLMSPVLGMCTSMAIGLINGGPLTIMLGFLISGVCIWFSSLSLGEIVSKFPMELHVGSAMLAPEKLKLVCSWYTGWLMLIGNWTMSTSITFAGAQLTISLILMTNSNLISEAHLIFYTVIVFYLVVTVVGLVNLKFARFIETINKVCVYWIIYAIIFIDILLLVFHKGKFRSLKYALFHFDNNLSGYKSAFLSFIIGFQQSNFTLQGFSMLPALADEVKVPEKDIPRGMSNAVLLSAFSGVIFLIPIMLILPDNDLLFTNHKVLPIVNIFTKSTDSVVLSFFLVLLILGNLLFSGIGSITTSSRAVYSFSRDQAIPYYDKWTYVEPDSQSKVPKNSVVLSMIISYFLGLLALISTAAFNAFIGAAVLCLCSATFIPLVLVLFTRRRAIRSAPVKIRYKFGWFINIVSIVWLLLSMVSVCLPTQVPVTFKTMNYALMVYVFCILVITGLYFKWGKYNFRLPLADDIKAPIPSDAEETVFELEDSNVEHTLNSGTTVKESVENNSEEGFIKVHPKSSTENPFEENEENVITDYGDEHHTAEQEFDLADDRRYDI", "length": 618, "molWeight": 69243, "crc64": "035CB927C624CE74", "md5": "9368784173000919B196384C90E46C47"}}
{"primaryAccession": "P36534", "text": "This is Large ribosomal subunit protein uL24m protein, from Baker's yeast, contains 297 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36534", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein uL24m", "length": 297, "firstPublicDate": "1994-06-01", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL24 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSGSYQHLSNVGSRVMKRLGNRPKNFLPHSEKFIKKSTPEFMKSDLKEVDEKTSFKSEKEWKFIPGDRVVVMSGASKGNIAVIKSFDKRTNSFILDENGPTKTVPVPKQFWLEGQTSHMITIPVSILGKDLRLVADIDDEKTPGKTRTVAVRDVSFNGSYYDADYKKVMPYRCVKGQPDLIIPWPKPDPIDVQTNLATDPVIAREQTFWVDSVVRNPIPKKAIPSIRNPHSKYKRGTLTAKDIAKLVAPEMPLTEVRKSHLAEKKELAEREVPKLTEEDMEAIGARVFEFLEKQKRE", "length": 297, "molWeight": 33751, "crc64": "D5BB2B7AE13ECBF9", "md5": "39F3299318C94F1B2844D4CDA0B815B0"}}
{"primaryAccession": "P36589", "text": "This is Cell division control protein 14 protein, from Fission yeast, contains 240 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36589", "organism_name": "Fission yeast", "protein_name": "Cell division control protein 14", "length": 240, "firstPublicDate": "1994-06-01", "FUNCTION": "Has a role in the septation initiation network (SIN) required for cytokinesis", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEDLLNNAKQHLCMRNPKLIRIGLRQVESIVYHVAKPSHDDKIPREIFLKLQDSPLYNSTTPCIYALDSLLEYQQNEEAYEKNFQFIQKLIDDLLHVIEGLVLIHPKSQTLFEDKATLRLFIHLLQPSQPSMLQVAAMKTLVCIMADRPLAIRLFEQINGLQQICVVFKHKQTSQDTRFQILEFFYFYLSPEPYSIDVIAYRKTRTEKQAYLSKYLSNVQGLRDDLDKFQPFGKLDETFD", "length": 240, "molWeight": 28161, "crc64": "4E67626A0C8E0716", "md5": "3A21B74C6B56A03F71ED85A91C868410"}}
{"primaryAccession": "P38172", "text": "This is MIOREX complex component 3 protein, from Baker's yeast, contains 270 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38172", "organism_name": "Baker's yeast", "protein_name": "MIOREX complex component 3", "length": 270, "firstPublicDate": "1994-10-01", "FUNCTION": "Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRTIPFLFKLVNRAVILPTAGFTLGVGAFVKAWPDDAGVLSLNDPQTPAELISATKSRQPMELQRVDILAQIEKSEVYNKLAQDEKMHHVLFSEKIPSGHREYHVGQGLLFGKGKLEIDPLVFHDVNHGELTVIYHLGAELGNRDGNVHKGLLSLLLDEALCYCGFPLLPSKRGVTARLSLEFFEDIPVDTTIILKANVKEIKGRKCIIEGHLEQFPLEVSSRNGTRSWNLPHIWGFNHKQEMAKKFAKANCILVEPTWFKYFKWLDMF", "length": 270, "molWeight": 30545, "crc64": "76DD3249586A2A0E", "md5": "1FB0B81A0DD5436F8B36975834234934"}}
{"primaryAccession": "P38325", "text": "This is Mitochondrial outer membrane protein OM14 protein, from Baker's yeast, contains 134 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38325", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial outer membrane protein OM14", "length": 134, "firstPublicDate": "1994-10-01", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSATAKHDSNASPNSDSEDGHHHNNKKECAIEYLKARLNSASAVACGYLQAFVSKTQDFAKVCFLELQNPVVLVNLLLHSSVVCYLCNGYANHNARFLKGKPNSTVLATTAGALGLLTLDGIISKKYYSRYDKK", "length": 134, "molWeight": 14610, "crc64": "2B4E4E35C283473D", "md5": "D4A964E6294C8F14C1F5AAE1BB469A81"}}
{"primaryAccession": "P38702", "text": "This is Mitochondrial carrier protein LEU5 protein, from Baker's yeast, contains 357 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38702", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial carrier protein LEU5", "length": 357, "firstPublicDate": "1995-02-01", "FUNCTION": "Required for the accumulation of coenzyme A in the mitochondrial matrix", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTRDSPDSNDSYKHINKNTTQKTSFDRNSFDYIVRSGLAGGISGSCAKTLIAPLDRIKILFQTSNPHYTKYTGSLIGLVEAAKHIWINDGVRGFFQGHSATLLRIFPYAAVKFVAYEQIRNTLIPSKEFESHWRRLVSGSLAGLCSVFITYPLDLVRVRLAYETEHKRVKLGRIIKKIYKEPASATLIKNDYIPNWFCHWCNFYRGYVPTVLGMIPYAGVSFFAHDLLHDVLKSPFFAPYSVLELSEDDELERVQKKQRRPLRTWAELISGGLAGMASQTAAYPFEIIRRRLQVSALSPKTMYDHKFQSISEIAHIIFKERGVRGFFVGLSIGYIKVTPMVACSFFVYERMKWNFGI", "length": 357, "molWeight": 40825, "crc64": "16266B2CD4B996D5", "md5": "70A3DBE63A23BF4D84D6B0855668A1C0"}}
{"primaryAccession": "P38732", "text": "This is Protein-lysine N-methyltransferase EFM1 protein, from Baker's yeast, contains 585 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38732", "organism_name": "Baker's yeast", "protein_name": "Protein-lysine N-methyltransferase EFM1", "length": 585, "firstPublicDate": "1995-02-01", "FUNCTION": "S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates elongation factor 1-alpha (TEF1/TEF2) at 'Lys-30'", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the class V-like SAM-binding methyltransferase superfamily, RKM1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MITQTELDNCLQWAQNNGAFIDPKISFRITEDAGVSAFVNEKFSPKPDQALIRVPETLLITSQQALSEFSQAANERSLLNSVTQLYLSKLKFGTDAVHLKSFYKPYLDVLPLHLPQPYFWSTDEVMNLHGTDVYLTMRDTLNKLVKEWRMLFQALSIEHSSQDKQFLSLFQENKDSAVVPLEQFCAHINGCKLEDSEWNSFVAYLWSYCIFNSRAFPRVILGRAGTDRTNLNEGFLYPIVDLLNHKNDVPVRWEMNEQNELCFMSQTTTFSAQDELFNNYGNISNEKCLLNYGFWDSSNKFDFSRLTLKLPSTLVSGLPVDFNKSGNFVTDDGETTILQFSLKISEPLPPVLLALFAYLSKLKSEETPTVRSVLEGIDQLTSVVSQRLLFYKNFKIKTSSTQKLRPHVIKLIKLYYQDNKKILNATTEKLSVLQKKIYSNNKEFSLSFKTIFKNDKIFANSLLLVFGAINYEDLITKDCLNDALLLWIVKLINDKSNNQGGFIKQTFKEVSDSIVIEKEDVMEFLPFYKKYFPNLSERIPEIYSVGDWGIRQFIVADTAIDRLVWIRKSNKEPIFLMKKAYDLQI", "length": 585, "molWeight": 67452, "crc64": "84BC2D3A204D9D29", "md5": "51513CCE0E4DFA089A577C13C18D472D"}}
{"primaryAccession": "P38848", "text": "This is Peroxisomal membrane protein PEX28 protein, from Baker's yeast, contains 579 amino acids, is membrane-bound, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38848", "organism_name": "Baker's yeast", "protein_name": "Peroxisomal membrane protein PEX28", "length": 579, "firstPublicDate": "1995-02-01", "FUNCTION": "Involved in the regulation of peroxisome number, size and distribution", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the peroxin-2832 family, Peroxin-28 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSETSSSRRSASKDAVKSYFAGKYNKVLDSILEAEAAISKSPTVAEDLSGSSSSGNSEMSHPSLTASSATSQGISKKELLQQIAGSLFSTSIERLKTAHSSEVSSTPEYSVNDSYGEQECRECDGVFKCSAHFEGAPEYYDDETESGPALEPMTSNSEKDPFIDVFLDKLISRLVPEKLPEREHFSSKTTIEHDLDTGRVPVFSATTLGSNFKKLSKKMGSIFELQDSIVRLLTWRNPTGTVTSLILFTLICFNPMYLVILPIFRFVYGIVVPGYVRKHPLQRSIYPLKRNHGSSLLYDVCYEGKNEYSYGQQFFSKSFMDTLESRNQEIDEISELDKRTENTGELKQGMKVLINLRDMQNMTSGTLHVIEAINSFLRKSSSFQNEECSTKRFFTGFLLIVFLKILSPFVNWSYVCSIFAWCLLIYMHPRAHPKIISFFKTGTMGKEYKNLKKREHQALNMIFDEQPETKFIEIFEIYKKALLPNDWKFFRYSNRIFDPQDPYRRAQQFPPGVDSLADVIPPTGWSFDPNFEWKIDNDVDRWVVERGLNLPITGEFLFDPMFKRRRLIHRVIKNATPVA", "length": 579, "molWeight": 66148, "crc64": "2A6A73999C54C19E", "md5": "9ECF1C0E8437566618CBB8A82E8A3167"}}
{"primaryAccession": "P38854", "text": "This is Topoisomerase I damage affected protein 11 protein, from Baker's yeast, contains 504 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38854", "organism_name": "Baker's yeast", "protein_name": "Topoisomerase I damage affected protein 11", "length": 504, "firstPublicDate": "1995-02-01", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the TDA11 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNKFDEFIESNEKDLDVDTSTRNSIISMSPVRKTGRKIRSASSNGYRLEHHRTSSAGSMHSQRLMTPTRLNDQDHPLQAKPDARRVVTRHSSVSVPNAMSKRRSLIQPMVVPTTPESQNNLPSVSHSEGSYGIPLESTTVLSSEQAMASGLRRSRNGSSQSVNSMIATTIPTNGVDVSALLQSLATKELELLECKQKIEDLKKQTQHEEQNYTRRARELHELKEQVSKHLDPSLNTPVKNRAFSPVYQNIPLESRTENAGNSSLPSSVSKPKNMGHQSTNQSRSVSPQDIQERRQRDDSSDSSKQSLWSKPLALFNQFDKIIQHEIERTLNWDDSLSGTPEVQEGTPTSNSESSAQQYDNEAPGARQKSPSQGSVSRSLWSFVSDVKAGLLGIEEENDNDVITDNRCDPVYKSDRQHEQKKSTHKITNRGQAEDSGDDSSLNMRKFKTTTKFQKDNAGNNSLTDESGHRTREKKSKRSSNKLSFIGEPDNDNSSVKNSVEMTDF", "length": 504, "molWeight": 56314, "crc64": "AE8B894335D1DB63", "md5": "4262ED86F78DF18B3303C52C7D3FC208"}}
{"primaryAccession": "P39551", "text": "This is Pheromone-regulated membrane protein 9 protein, from Baker's yeast, contains 298 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P39551", "organism_name": "Baker's yeast", "protein_name": "Pheromone-regulated membrane protein 9", "length": 298, "firstPublicDate": "1995-02-01", "FUNCTION": "May be involved in endoplasmic reticulum exit trafficking of proteins", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the DUP/COS family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSPQYHFYFVSFRNLVLNEKCLRSKKQVMKSFNWYKTDRYFDPHNILQHHSRAIEKTRYKLGMQTSSESTDAKSDFLDEPSAYLIEKNVALPKDIFGSYLSYWIYEVTRHKAAVILLVLIVTSILLLVFFYNTEFCVAFEILLFSFCFPGTCMVVIAFSEPIGDREFKVKLLMEIITRKPAVKGKEWRTITYKMNQYLFDHGLWDTPYYFYRDEDCHRYFLSLIKGRTFKKQKESSASNVKDAQSNDETAGTPNEAAESSSFSAGPNFIKLLTKAAEIEQQFQKEYWRQEYPGVDEFF", "length": 298, "molWeight": 35073, "crc64": "2CCB50B4D73DAB71", "md5": "85EE7D38BD11543091A5F80D0AD880F6"}}
{"primaryAccession": "P40006", "text": "This is Increased recombination centers protein 22 protein, from Baker's yeast, contains 225 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40006", "organism_name": "Baker's yeast", "protein_name": "Increased recombination centers protein 22", "length": 225, "firstPublicDate": "1995-02-01", "FUNCTION": "Is probably involved in a pathway contributing to genomic integrity", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the IRC22 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRFSMLIGFNLLTALSSFCAAISANNSDNVEHEQEVAEAVAPPSINIEVKYDVVGKESENHDSFLEFYAEDTATLAYNVTNWEDTNITIFGVNGTIVTYPHGYPVADITGASIGPYEMEVNGTSKFGQDVTLNLPEGQYFLIPFLLASRFDEIVRIAAPPTLFEIVSPPISFFNPQFLSVQVIFLAIIGGVSYYYMKSKTNQRPSKKSATVKKVDESWLPETYKK", "length": 225, "molWeight": 24992, "crc64": "94C23FF5C98B8C39", "md5": "1CCEE52666F57B4974F417CDC09FCC55"}}
{"primaryAccession": "P40156", "text": "This is Required for respiratory growth protein 9, mitochondrial protein, from Baker's yeast, contains 214 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40156", "organism_name": "Baker's yeast", "protein_name": "Required for respiratory growth protein 9, mitochondrial", "length": 214, "firstPublicDate": "1995-02-01", "FUNCTION": "Required for respiratory activity and maintenance and expression of the mitochondrial genome", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the RRG9 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNILRIACRSFHCLRCGPLLNENRGWSSKKIIKLVNKSSLSNKEFTEKVRDGTKDIPEWKKQKMAVRKKLQGQRWNPPKKISQEQMEALRLLKFNFPELTASDLADRFKISPEAVRRILKSNWKRTDEENNNTYERWKRRGERIKEMYQRKEDADFVSNQIVTSRKIILGSNSNSPELIARNVRTFKPFKPNNSTPEKKNTNKLYILKHLGSKQ", "length": 214, "molWeight": 25274, "crc64": "D1564C8905C3A985", "md5": "013B80E3B038FC329558F0C832914778"}}
{"primaryAccession": "P40525", "text": "This is Large ribosomal subunit protein eL34B protein, from Baker's yeast, contains 121 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40525", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein eL34B", "length": 121, "firstPublicDate": "1995-02-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eL34 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAQRVTFRRRNPYNTRSNKIKVVKTPGGILRAQHVKKLATRPKCGDCGSALQGISTLRPRQYATVSKTHKTVSRAYGGSRCANCVKERIVRAFLIEEQKIVKKVVKEQTEAAKKSEKKSKK", "length": 121, "molWeight": 13641, "crc64": "6B0AD076CD85ACF4", "md5": "438DD32B7CF9E626E953C86C69413B56"}}
{"primaryAccession": "P40531", "text": "This is Protein GVP36 protein, from Baker's yeast, contains 326 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40531", "organism_name": "Baker's yeast", "protein_name": "Protein GVP36", "length": 326, "firstPublicDate": "1995-02-01", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSFNAFASSLSKKLQEISTSVSEKTQELPSLAQSTQRMVQERLGQVTDISQLPREYTELEDKVDTIKLIYNHFLGVTAIYENGSYDYPKYINESVNEFSRSVASKLTELTHATSASEAQNILVAPGPIKEPKTLNYALSKVALNSSECLNKMFPTEEQPLASALLQFSDVQAKIAQARIQQDTLIQTKFNKNLRERLSFEIGKADKCRKDVHSMRLRYDVARTNLANNKKPEKEASLRVQMETLEDQFAQVTEDATVCLQEVISHANFSEDLKELAKAQAEYFETSAGLMKEFLSNSFAEEPEAKPEVAEEEKPQTAISMNDEDDA", "length": 326, "molWeight": 36670, "crc64": "A692CE1C7A62F351", "md5": "42353946F59B87D3366BCB781D04B0D9"}}
{"primaryAccession": "P40546", "text": "This is Protein FAF1 protein, from Baker's yeast, contains 346 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40546", "organism_name": "Baker's yeast", "protein_name": "Protein FAF1", "length": 346, "firstPublicDate": "1995-02-01", "FUNCTION": "Required for pre-rRNA processing and 40S ribosomal subunit assembly, Seems to act in the processing of 35S rRNA at the A(0), A(1), and A(2) cleavage sites", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTLDDDDYIKQMELQRKAFESQFGSLESMGFEDKTKNIRTEVDTRDSSGDEIDNSDHGSDFKDGTIESSNSSDEDSGNETAEENNQDSKPKTQPKVIRFNGPSDVYVPPSKKTQKLLRSGKTLTQINKKLESTEAKEEKEDETLEAENLQNDLELQQFLRESHLLSAFNNGGSGSTNSGVSLTLQSMGGGNDDGIVYQDDQVIGKARSRTLEMRLNRLSRVNGHQDKINKLEKVPMHIRRGMIDKHVKRIKKYEQEAAEGGIVLSKVKKGQFRKIESTYKKDIERRIGGSIKARDKEKATKRERGLKISSVGRSTRNGLIVSKRDIARISGGERSGKFNGKKKSRR", "length": 346, "molWeight": 38889, "crc64": "7DE47A11F3952575", "md5": "28F7EBEDE78FA85AC75914D299CE28B6"}}
{"primaryAccession": "P41000", "text": "This is Protein cps3 protein, from Fission yeast, contains 583 amino acids, has 2 C3H1-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [35, 62], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [64, 91], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "P41000", "organism_name": "Fission yeast", "protein_name": "Protein cps3", "length": 583, "firstPublicDate": "1995-02-01", "FUNCTION": "Responsible for supersensitivity to the spindle poison, isopropyl N-3-chlorophenyl carbamate, Has a role in meiosis", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"C3H1-type Zinc finger": 2}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTKKNAFKNSEDMKKYHLSEFNSEATSLTRPSPKSLQHVPCKFFRQGTCTSGKNCIFSHDLELATEKTICKYFQKGNCKFGSKCALEHVLPDGRKVKTRAFAPSTTAMGSSSQNISAAPMANIISNNDKILPMTTMASATASEEKNRIKDEALVIKKEESNVAIPSEVTVAANAFSASTEDVYSIVGDSLSKKASVKDFSDVTGIETIPAYVEATNGSSTVRSPHAKRSLSSISVKSSTSPFSGSKFLSSSSYPHTPEAHLNSNHISPASFGSGIRTRNIFNPESMSLGLKPPILNRSYSASMAPGFSMNTFTATGNLGRPTKSPSVPTSVGSNKSRKFPGINGSTLTATPSSLENLYPLSSRRSVPNLISSLGTSPSTFSSQFLKSTDRTHSFTSKLQSFNPVGTSLLASSLGTSQEDSVNYDIPDEFANEEDFIPNSLQELLTPEELERKMSHGDEAVSSSSASRFMSKVSSNLNSGNPTPYNSYNGTPTSSRFVAFFDRHRQESEKATPPSLNKVSQEPLTATTPKNLGNLTAISETLENGQTLKSNMASSIEKSKTSTEVVASYDTTLDEETQFQMDEA", "length": 583, "molWeight": 62808, "crc64": "905022C7C06E4271", "md5": "EF05930EE352BCDA4F1FB7526150F738"}}
{"primaryAccession": "P42223", "text": "This is Protein SBE2 protein, from Baker's yeast, contains 864 amino acids, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P42223", "organism_name": "Baker's yeast", "protein_name": "Protein SBE2", "length": 864, "firstPublicDate": "1995-11-01", "FUNCTION": "With SBE22, is involved in cell wall integrity and polarity processes like bud growth, through the transport of CHS3 and UTR2 to sites of growth", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTARRLINIVPNTSKLDPLKEEDSTHLKQNQPKKFSTKELMLSEYTERKSCSLPLSKSRSGSSASSSTTGSNGKNIGTRRPSSNLDFNFASQDVVKNVLGNNNPHVPTAKCIRPISDDSIGTSSTEIFSSSHSNTTSDSLCTSDISSEEGEIANSKMEDNCFFKSMREADHRSNITPLKKSRPGSILQKTRTASSADKTICSMSTITTCIPSRQNSVSTPKLSRTVGLPGSSNTTNSIAASQTSFISENDSPLKHHCMSTATIQEPKLMPITKTPYVHSNSTSVILPYKTTQLTPSQRYRLRKEQNDQSLRKAIKMKEKFYEDQDVNLELQEGDVDGSLIWNIPMASLSTSSFLTLSKFNRKEMSLDSARGDEEILIQENNCEGKQHSSSALCVDKTFHQVHSTRKHTSNSSNTLKESCLDYKELPPTCIPGISPVSDSQYIQDTMKNLSQIYLHSSEKISKSILSGRSRSVQSLPLEFKEASSQGMEDLMLVSEDKLKAVSHFRPSWLPPKDFKERKLQDKQIYKNIDLASMEELQKNKERDEKAKKNEQNKVKFQHLLDRGITRNSSLSELKKIIWETPLISKVRLQIYSQLLQSDNCLITKCFIESFEEVMQLLNKMDFPKDKEFEIRQLIEHDVQEKVFYKNGTDKQVVSDLMLLLQLKSISQQGLVTGDEMLFYHFLTDQSFGTLKETWEMVNLIQMTCFSEICKEKYDSRILNPRGIVAHLLRKDEFKNEFNGGCLNSNTWWNILQRMDHKLFMWVMDVIIVHNGQNFANYPVKMEIFKDKVWEYYRSKKVIVNYKILVSLTVNVLLNYHFGYDNLKHLSDLDDKHFCIPLYTEDSIEEENLNNIFTKWWLHYYRKLR", "length": 864, "molWeight": 98971, "crc64": "9491912ECF6F9406", "md5": "DDFF28F02B12C027297FBC237A21665F"}}
{"primaryAccession": "P43613", "text": "This is ER-localized J domain-containing protein 5 protein, from Baker's yeast, contains 295 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P43613", "organism_name": "Baker's yeast", "protein_name": "ER-localized J domain-containing protein 5", "length": 295, "firstPublicDate": "1995-11-01", "FUNCTION": "DnaJ-like chaperone required for the folding capacity of the endoplasmic reticulum", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DnaJ family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNGYWKPALVVLGLVSLSYAFTTIETEIFQLQNEISTKYGPDMNFYKFLKLPKLQNSSTKEITKNLRKLSKKYHPDKNPKYRKLYERLNLATQILSNSSNRKIYDYYLQNGFPNYDFHKGGFYFSRMKPKTWFLLAFIWIVVNIGQYIISIIQYRSQRSRIENFISQCKQQDDTNGLGVKQLTFKQHEKDEGKSLVVRFSDVYVVEPDGSETLISPDTLDKPSVKNCLFWRIPASVWNMTFGKSVGSAGKEEIITDSKKYDGNQTKKGNKVKKGSAKKGQKKMELPNGKVIYSRK", "length": 295, "molWeight": 34191, "crc64": "4541BF6C353DB8AC", "md5": "E43624ADD01739AEEF1E4DF0BCE8102C"}}
{"primaryAccession": "P45815", "text": "This is Copper resistance protein CRF1 protein, from Yeast, contains 411 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P45815", "organism_name": "Yeast", "protein_name": "Copper resistance protein CRF1", "length": 411, "firstPublicDate": "1995-11-01", "FUNCTION": "Transcriptional regulator involved in resistance to high copper concentration", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVVIEGIKYACERCIRGHRVSSCTHTQQPLIRIKPKGRPATQCLHCREARKNKALHVKCKCGSSSSKHAATCPCYSGGGCICTNKHPQVLPPNSTTTGANGCIVINKAVLDEGSQQQAQQAQQQSQSQQAQQQQQQPQPQASPILQQPQMPTPVHTTNVTTPPVATPTHSHRALSTTPSLSPQPQSPHSPESALKSVNFLGRTNSSSSLSSLHSGRNKNRIEKVRPSHNSLSAASQLANSPSSPFYAVTPPAWVDSPTLVPTGALDASYLQILNDDLSSPLLDSDVFSSLDMEPVAHSNNNHGGIPTGGSRALASTDINFDRFESTSPSSILSSWNLWGGVGGSDAPEMSVAANPSASASASSIQTPPSSNATPEWVQGQQQPCSVSPADVMLPFKRDDQESVFLTEPLYL", "length": 411, "molWeight": 43689, "crc64": "9AD602FA467EACC7", "md5": "F8064C80E25315367F7ADCF193B6E8A7"}}
{"primaryAccession": "P46992", "text": "This is Cell wall protein YJL171C protein, from Baker's yeast, contains 396 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P46992", "organism_name": "Baker's yeast", "protein_name": "Cell wall protein YJL171C", "length": 396, "firstPublicDate": "1996-02-01", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the PGA52 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLQSIVLSVCMFMLHTVAASGPQSYQKLDFTNVGFTGSYVDVNKFKDITNNESCTCEVGDRVWFSGKNAPLADYLSVHFRGPLKLKQFAFYTSPGFTVNNSRSSSDWNRLAYYESSSKTADNVTFLNHGGEASPCLGNALSYASSNGTGSASEATVLADGTLISSDQEYIIYSNVSCPKSGYDKGCGVYRSGIPAYYGYGGTTKMFLFEFEMPTETEKNSSSIGYYDLPAIWLLNDHIARTSQYPTNANCSCWASGCGEYDIFEAMNGTEKNHLYSTFHTFQGIEDLGTGIQSYGYITRNTTGTMKGGVVFDSSGNVVSFISDATPFNGTVSADTVNDLLAAIPENETYSSQLMSISATAPSTTSKSNGVALTKMQNGVWYYILAIFTAFTQVVLI", "length": 396, "molWeight": 42958, "crc64": "979CB4AD751266CC", "md5": "9C151B256C54589AE482EF4AC531DDBC"}}
{"primaryAccession": "P47155", "text": "This is Protein ILM1 protein, from Baker's yeast, contains 203 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P47155", "organism_name": "Baker's yeast", "protein_name": "Protein ILM1", "length": 203, "firstPublicDate": "1996-02-01", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the ILM1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAQALNSTNIAFFRVAFLFTIAFFCLKNVNSILQNTYFIVLTQAMNLPQLTLSRYSGQLGLFALLFTLNGVHDLIPLLENNVKYFQSVVPVRLLIFFILTSISYLWESNFYVHNNSVFIYCFAEVWINFLLYNAIREEKNEEFKRLNQFMVNDEDIEEPQPFTVKTETTEIIEIINDEENDDEDGKDNDDNNEKGNDDSDAKK", "length": 203, "molWeight": 23645, "crc64": "F7F27F4D0BF61F53", "md5": "67577D39D7B79B9674CF2ED38D7D6BC4"}}
{"primaryAccession": "P52554", "text": "This is Probable prefoldin subunit 6 protein, from Caenorhabditis elegans, contains 126 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P52554", "organism_name": "Caenorhabditis elegans", "protein_name": "Probable prefoldin subunit 6", "length": 126, "firstPublicDate": "1996-10-01", "FUNCTION": "Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it, Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity), Required for positioning of the mitotic spindle", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the prefoldin subunit beta family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MADMAKFEEEVNKLRTLEKDREKYFTSRQEMEMRLTESKNVKAELDLMESDSKVYKLIGAVLVRQDLEEARSTVEKRLEFIDSETKRVEASISDISKKCTEQRDKVMNMQKSFQMMAQAAAQAQKK", "length": 126, "molWeight": 14737, "crc64": "7EE42114C958B4EF", "md5": "556E1EC4449A564A2EA94831AF19DADE"}}
{"primaryAccession": "P53139", "text": "This is Uncharacterized protein YGL108C protein, from Baker's yeast, contains 140 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53139", "organism_name": "Baker's yeast", "protein_name": "Uncharacterized protein YGL108C", "length": 140, "firstPublicDate": "1996-10-01", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "To S,pombe new13", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGLCGSKTQPMPSQTTTVATKARTKPINRDTVKSKQELRHKEKKDKKKKTQLKSTTVPVVQRKEGSKLTDTSDPSKNKVSPKEAARLAAEKRFQETNEKYNKGELGKKLAQERAKSHKTRLMEEAEKKHAERERENMIYD", "length": 140, "molWeight": 16037, "crc64": "89C6AEC296CA9E57", "md5": "5830C1389E7657ADD1B64FA49C4ACDDA"}}
{"primaryAccession": "P53394", "text": "This is Putative sulfate transporter YPR003C protein, from Baker's yeast, contains 754 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53394", "organism_name": "Baker's yeast", "protein_name": "Putative sulfate transporter YPR003C", "length": 754, "firstPublicDate": "1996-10-01", "FUNCTION": "Possible sulfate transporter", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the SLC26A/SulP transporter (TC 2,A,53) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTSNNSLLGRGRMSYSSTAPPRFKRSVDQRDTFSDNFDYDKDSSNRGRTYIAASNSTTGVPPPNNSRSGCTNNTNNTNNTSNTSNTNNNDSVDENTVFETLPYYLPCFSWLPEYTFNKLWGDVIAGISVASFQIPLALSYTTSIAHVPPLCGLYSLAISPFVYGILGSVPQMIVGPESAISLVVGQAVESITLHKENVSLIDISTVITFVSGTILLFSGISRFGFLGNVLSKALLRGFISSVGLVMIINSLISELKLDKFLVSLPQHYHTPFEKILFLIDYAPAQYHIPTAIFSGCCLIVLFLTRLLKRKLMKYHKSAIFFPDILLVVIVTILISMKFNLKHRYGISIIGDFSMDNFDELKNPLTRPRRKLIPDLFSASLIVAMLGFFESTTASKSLGTTYNLTVSSNRELVALGFMNIVISLFGALPAFGGYGRSKINALSGAQSVMSGVFMGVITLITMNLLLQFVHYIPNCVLSVITTIIGISLLEEVPGDIKFHLRCGGFSELFVFAVTFCTTIFYSIEAGICIGCVYSIINIIKHSAKSRIQILARVAGTSNFTNLDDYMMNMKRNSLDVEGTEEIEGCMIVRIPEPLTFTNSEDLKQRLDRIERYGSSKIHPGRKSLRSKDSIKYVIFDLGGMTSIDSSAAQVLEEIITSYKRRNVFIYLVNVSINDKVRRRLFKAGVAASVERAQANNNENNTSNTFSDAGETYSPYFDSIDAALYEIEKMKIKGNNVPNNDSESFMSNTLFNSSLV", "length": 754, "molWeight": 83384, "crc64": "4558DA8B79803E6E", "md5": "97DA2F24766F9A1683B6665FF7C5170D"}}
{"primaryAccession": "P53882", "text": "This is Topoisomerase I damage affected protein 7 protein, from Baker's yeast, contains 636 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53882", "organism_name": "Baker's yeast", "protein_name": "Topoisomerase I damage affected protein 7", "length": 636, "firstPublicDate": "1996-10-01", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the TDA7 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNSNSTIGRTTLGESDTISLSFSEPSSSLNSRSTDVVFASTSTLVPQQGSLTSLPPVSSTATPTYYSTSLTYDETLHTSIDVSSTSTLVSSTDSSSSSEQDTYSSQYDPATSSYSIITPSMSIFSSTSPMSSSSSITSEWSSLTSTTPTLSSSATSLSSSWSSLSSPSSLLVSSSLSLSLSSSYSDTKLFSFDSRSSIFSPSTPTVISPSYTYLSSISATSFQISTTSELSSSWFSTISSPSTISNKDTTFPSSSRNTSTSFYSSSLSSTNDFSTISKSSKLSPSASSSTVSISTISVPTSSSVSSSSSKVPSNRPSSSSSSDDTTSAYSSTYTFQSLQSTTSSSIPPTTQTPSTSTISTSPIPTSSQVFNTVAISSSEDSKTIYYFYTQTYDITDSSTTFVTGLPTTIAVAKSEVTSFSAPSSTITADMSFYQHWLDGSLDNNKNQGTSKTNTGTIVGSVVGSVGGILICVLVVWFMLVRKRKAKRHFKENDSFCHEIGRRTGFPTTAQAKEASLQAQDSGSQQRNTETASANNPFSNEFNFKARGNPPPVPPPRNVTAMNGSFQNMRSNFMDQENRFSYGSSFTYSSLGSSTQGGFSTLSSNSIRLGRGLDNDISHDERNTVQNNSQGFLREII", "length": 636, "molWeight": 67401, "crc64": "C6C228AEFFA43405", "md5": "F9907DC4E87A191D953B627272B27F6F"}}
{"primaryAccession": "P54005", "text": "This is Protein DIA1 protein, from Baker's yeast, contains 336 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P54005", "organism_name": "Baker's yeast", "protein_name": "Protein DIA1", "length": 336, "firstPublicDate": "1996-10-01", "FUNCTION": "Involved in regulation of invasive growth", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGSISRYLLKKAADGLKDEQRLKIEMSDSKSVPECFHFNRERRMPIAEINGEDGFFMFPSQQSLENFENTKKYSNELSPDAIGIPLFQIINCTLPFGKRGHSNTVVGNVPYYKIFKFILRTADEPPPYTVAKIVCSNNGLILYKVPLYDIYKNVSQANVTYSFVGTTSTEPNLLAMAHREGHRDLDTKVNNLNLRWHVTYSPVVTNDHYKLILLADYEVNRLDEDVIRAAKNKMSIDQKDQKVQRFVAAHYTREFETSLFRWVAQEGHLILGEYSTDQGSFGLNNIPPLTEELGCQSLLIHYIEYMKRQRKKIAKEARRQNKRNVANTTNMNMNLM", "length": 336, "molWeight": 38760, "crc64": "DCCDF2279AC92297", "md5": "0613C63A57AF5A8B6C6D54C0E2A78464"}}
{"primaryAccession": "P62597", "text": "This is Protection of telomeres protein 1 protein, from Chicken, contains 778 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P62597", "organism_name": "Chicken", "protein_name": "Protection of telomeres protein 1", "length": 778, "firstPublicDate": "2004-07-19", "FUNCTION": "Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini, Is a component of the double-stranded telomeric DNA-binding TRF1 complex that is involved in the regulation of telomere length by cis-inhibition of telomerase, Also acts as a single-stranded telomeric DNA-binding protein and thus may act as a downstream effector of the TRF1 complex and may transduce information about telomere maintenance and/or length to the telomere terminus, Binds to at least two telomeric single-stranded 5'-TTAGGG-3' repeats (G-strand), Its activity is TERT dependent but it does not increase TERT activity (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the telombin family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPVQVLKIIKGKPETQLPSHLQREDLKHLQTGLDHTNKYFQGIVILSYPLTKLGDGTDFFKIVLQDDTCSRINSINVLMYGKMAEDCAKLIRNGDTFIVAGFKVAESPTAREDGRHACHLQVSEESGSAIFICTQPSITPFSEATSPSVAPKYVYTPLNCLKDGTVVNLYGIVKFFKPPYISKGTDYCSVVTLVDQSNVKLTCTLFNGNLDSLPKIYKNGDIVRFHRVKIREYNGQMQGITSAGFASLTFDGTVGAPVVPRASSKVYTFVDEEQKTVEELRIWAASNLSVSGPEAKLSDVKPMMFFDLTCQLVGKAKVDGSSFLLKVWDGTKCPYPTWKVPVEAKELEGDRVLLHHLRNLTVDVLVYDNHVQLAKSLKTGSFLRIYSIHTKQASAKNEDMSSHIEFHLHGGTCYGRGIGILPENNPDVEELKSFLECVELTDSQNMESVSSLELGDTFDSYTDLESPLQRCQQLSATVLTDHQDMSNTVLKTVLNSSAPQQYRIRAKLRSFKPQKLYQSVKLHCSKCNTLQEVPNGDAIDFILQGCAATAPNPELQSMSWYESVVWTTEEDQGRKITIHFVKHYEMLQRPENTLLMIEGGTLKEIWKLTRRFKCVIPVKSKEDDLELLDLSAPFLLQGNIKYYGCKKCSTPKSIKNLSSLAEKREPSWEPTEIAQVLGIEPLQYVFVMKFTLVDGTGVLNAYLFDYEKFFQIPASEILTNSFLQQKMEMTMNTLSPPGRKLDDLPWLECFIKSYNVADGMKHQVYYQIFDTTVAEDVV", "length": 778, "molWeight": 87484, "crc64": "BD11397FAC6D0A53", "md5": "1153F9CE028136E9657A0787C563C6C2"}}
{"primaryAccession": "P82649", "text": "This is Small ribosomal subunit protein mS22 protein, from Bovine, contains 359 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P82649", "organism_name": "Bovine", "protein_name": "Small ribosomal subunit protein mS22", "length": 359, "firstPublicDate": "2001-04-27", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mS22 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MATLRVSLSLWNLHAGSRGAGRVYFRARARPRPGDLFQPLPGVCGAGTPCRGLCSEAESGSPKIKKPTFMDEEVQSILIKMTGLDLLKIFKPAVQETKPPTYKLMTQAQLEEATRQAIEAAKVRLKMPPVLEERTPINDVLAEDKILEGTETGKYVFTDISYSIPHRERFIVVREPSGTLRKASWEERDRMIQIYFPKEGRRVLTPVIFREENLQTMYSQDRHVDVLNLCVAQFEPDSADYIKVHHQTYEDIDKYGKYDLLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLVDDAASLVQLYHILHPDGQSAQEAKEQAAEGLQLIKVFAKTEAQKGAYIELTLQAYQEAFISSSAAS", "length": 359, "molWeight": 40665, "crc64": "BB5D8424A5DA354D", "md5": "D3F34D82F27B63CB63846ED373D76A84"}}
{"primaryAccession": "P82670", "text": "This is Small ribosomal subunit protein uS10m protein, from Bovine, contains 201 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P82670", "organism_name": "Bovine", "protein_name": "Small ribosomal subunit protein uS10m", "length": 201, "firstPublicDate": "2001-12-13", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uS10 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAVRAVFGALGRRLWQGSKNFSVSSSRSNIAKNDGFLLSTSMKWVQFSNLHVDVPKDLTKPTITISDEPDTLYKRLSVLVKGHDKAVLDSYEYFAVLAAKELGISVKVHEPPRKIERFTLLKSVHIFKKHRVQYEMRTLYRCLELEHLTGSTADVYLEYIQRNLPEGVAMEVTKTRLEQLPEHIKKPVWETTPEEKGDSKS", "length": 201, "molWeight": 23032, "crc64": "DFA29D78D6678E3E", "md5": "F35B821B54468CC33419A370E44505AC"}}
{"primaryAccession": "P82919", "text": "This is Large ribosomal subunit protein mL66 protein, from Bovine, contains 196 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P82919", "organism_name": "Bovine", "protein_name": "Large ribosomal subunit protein mL66", "length": 196, "firstPublicDate": "2002-10-19", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bS18 family, Mitochondrion-specific ribosomal protein mL66 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAALNVLVSGCGRFLRGLLTGPTVTSWARPPARGFREVVEIQEGKTTIIEGRITGTPKESPNPPNPSGQCPICRWNLKHKYSYEDVLLLSQFIRPHGGMLPRSITGLCQEEHRKIEECVKMAHRAGLLPNHRPKLPEGFFPKTRPRLNRYLTRWSPRSVKPIYNKGHRWNKVRMAVGSPLLKDNVSYTGRPLVLYH", "length": 196, "molWeight": 22281, "crc64": "0CAA7B308EAD5CF1", "md5": "74FEDE7F5A0A43DE94C82242F9DFDA48"}}
{"primaryAccession": "P82920", "text": "This is Small ribosomal subunit protein bS21m protein, from Bovine, contains 87 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P82920", "organism_name": "Bovine", "protein_name": "Small ribosomal subunit protein bS21m", "length": 87, "firstPublicDate": "2001-05-04", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bS21 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAKHLKFIARTVMVQEGNVEGAYRTLNRILTMDGLIEDIKRRRYYEKPCRRRQRESYETCRRIYNMEMARKINFLMRKNRADPWQGC", "length": 87, "molWeight": 10676, "crc64": "D28696851F9150E7", "md5": "D5CC9E81FEF3DCCE1F5AE73BFF23BA20"}}
{"primaryAccession": "P83183", "text": "This is Cysteine-rich protamine protein, from Curled octopus, contains 84 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83183", "organism_name": "Curled octopus", "protein_name": "Cysteine-rich protamine", "length": 84, "firstPublicDate": "2002-11-15", "FUNCTION": "Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis, They compact sperm DNA into a highly condensed, stable and inactive complex, This protamine condenses spermiogenic chromatin in a pattern which comprises fibers with a progressively larger diameter and lamellae that finally undergo definitive coalescence", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "FCGSKPRCRPRCKPRCRSRSKKRCRRCRRRCSRIVKKCCRRRSKCCRRRRRCPCPCPRKKLRCCKRRPKRRCPKRKKKRCRRKC", "length": 84, "molWeight": 10612, "crc64": "70932DAC3C71837E", "md5": "054867B95EB9BFC9EA9CD902761DA579"}}
{"primaryAccession": "P83428", "text": "This is Locustin protein, from Migratory locust, contains 55 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83428", "organism_name": "Migratory locust", "protein_name": "Locustin", "length": 55, "firstPublicDate": "2004-01-16", "FUNCTION": "Has antibacterial activity against Gram-positive bacterium M,luteus", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "ATTGCSCPQCIIFDPICASSYKNGRRGFSSGCHMRCYNRCHGTDYFQISKGSKCI", "length": 55, "molWeight": 6061, "crc64": "3A3B17AE7E6D7A8E", "md5": "5CFEC9BDCCC99B57317EF14D4111D298"}}
{"primaryAccession": "P83758", "text": "This is Doublesex- and mab-3-related transcription factor 3a protein, from Zebrafish, contains 448 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83758", "organism_name": "Zebrafish", "protein_name": "Doublesex- and mab-3-related transcription factor 3a", "length": 448, "firstPublicDate": "2004-05-10", "FUNCTION": "Probable transcription factor that plays a role in configuring the spinal circuits controlling motion in vertebrates, Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling movements, May regulate transcription (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the DMRT family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNGYGSPYLYMGGPVSQPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPESLRALPGITVSSGEQSANPRASDIDLRWNTETGTPKTPQDLSDELSGEQSGGENGGSDREPEAVSSPEESKPNLCCTPDTSDPSPQLEESRFGLSKSCSDPEPKSDNPKYSPEPNLLIEGLSGSVSLPFSLRANRPPLEVLKKIFPAHKPAVLELILKGCGGDLVGAIEILLSSRSTMKPEKILSESSDALVLPSNGHLFEHPLSSYPVSSSKWSVGSAFRVPDSLRFSSESSGGVVPGPLSMPLQHGFPQPPRYPLMLRNSLSRGQAGPFMHNDVTLWNTMTLQQQYQLRSQYVPPFSGPSAGVIRSSPLLTSRPSEEHRISIQEESCPVIAKQSMYAADEEYDDRSDSSDSRILNTSS", "length": 448, "molWeight": 48965, "crc64": "21E03094D9685464", "md5": "C43CDC2D51637911996A9E5761B7DAAA"}}
{"primaryAccession": "P83800", "text": "This is Crustacean hyperglycemic hormone protein, from Noble crayfish, contains 72 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83800", "organism_name": "Noble crayfish", "protein_name": "Crustacean hyperglycemic hormone", "length": 72, "firstPublicDate": "2004-03-15", "FUNCTION": "Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level, Has a secretagogue action over the amylase released from the midgut gland, May act as a stress hormone and may be involved in the control of molting and reproduction", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the arthropod CHH/MIH/GIH/VIH hormone family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "QVFDQACKGIYDRAIFKKLDRVCDDCYNLYRKPYVATTCRQNCYANSVFRQCLDDLLLIDVVDEYISGVQIV", "length": 72, "molWeight": 8409, "crc64": "D638832940AD4DE3", "md5": "4A0BD92E9332591B384ED9A8B3A2AEC7"}}
{"primaryAccession": "P84033", "text": "This is U21-ctenitoxin-Pn1a protein, from Brazilian armed spider, contains 245 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P84033", "organism_name": "Brazilian armed spider", "protein_name": "U21-ctenitoxin-Pn1a", "length": 245, "firstPublicDate": "2004-07-19", "FUNCTION": "Protease, Hydrolyzes gelatin and succinyl casein", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "IVYGTVTTPGKYPWMVSIHERVKDVMKQACGGAILNENWIVTAAHCFDQPIILKDYEVYVGIVSWLHKNAPTVQKFQLSKIIIHDKYVKDGFANDIALIKTATPIDIKGSKYGVNGICFPSGATDPSGEATVIGWGMIRGGGPISAELRQVTLPLVPWQKCKQIYGHPDSEFEYIQVVPSMLCAGGNGKDACQFDSGGPLFQYDKKGVATLIGTVANGADCAYAHYPGMYMKVSAFRSWMDKVMT", "length": 245, "molWeight": 26776, "crc64": "EDDEB2E8B02101D4", "md5": "977D3B0E1681CD8ADB80A4A001F7CE5C"}}
{"primaryAccession": "P84808", "text": "This is Cysteine-rich venom protein kaouthin-2 protein, from Monocled cobra, contains 238 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P84808", "organism_name": "Monocled cobra", "protein_name": "Cysteine-rich venom protein kaouthin-2", "length": 238, "firstPublicDate": "2006-04-04", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the CRISP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIAFIVLLSLAAVLQQSSGTVDFASESSNKRENQKQIVDKHNALRRSVRPTARNMLQMEWNSNAAQNAKRWADRCSFAHSPPHLRTVGKIGCGENLFMSSQPYAWSRVIQSWYDENKKFVYGVGANPPGSVIGHYTQIVWYNSHLLGCGAAKCSSSKYLYVCQYCPAGNIIGSIATPYKSGPPCGDCPSACVNGLCTNPCKHHNVFSNCQSLAKQNACQTEWMKSKCAASCFCRTEII", "length": 238, "molWeight": 26216, "crc64": "0B6CB4FEA3272570", "md5": "201983EF2DF6978F9EF10A24CAF2FF74"}}
{"primaryAccession": "P86037", "text": "This is Raniseptin-1 protein, from Chaco tree frog, contains 80 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86037", "organism_name": "Chaco tree frog", "protein_name": "Raniseptin-1", "length": 80, "firstPublicDate": "2009-05-05", "FUNCTION": "Has antibacterial activity against the Gram-negative bacteria E,coli ATCC 25922 (MIC=5 uM), P,aeruginosa ATCC 27853 (MIC=10 uM) and X,citri (MIC< 2 uM), and the Gram-positive bacterium S,aureus ATCC 29313 (MIC=20 uM), Does not have hemolytic activity against human erythrocytes", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Dermaseptin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGIVSLSICEEEKREGEEEEKQEEENEELSEEELRERRAWLDKLKSLGKVVGKVALGVAQNYLNPQQ", "length": 80, "molWeight": 9253, "crc64": "C36A694D6F760B21", "md5": "8B3E41CE1984C2EDA4255275005B556D"}}
{"primaryAccession": "P86040", "text": "This is Raniseptin-7 protein, from Chaco tree frog, contains 80 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86040", "organism_name": "Chaco tree frog", "protein_name": "Raniseptin-7", "length": 80, "firstPublicDate": "2009-05-05", "FUNCTION": "Has antibacterial activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Dermaseptin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGIVSLSICEEEKREGEEEEKQEEENEELSEEELRERRALLDKLKSLGKVVGKVALGVAQHYLNPQQ", "length": 80, "molWeight": 9203, "crc64": "C36A6957DEDD0E81", "md5": "0EC3C38ECCEC91B860AE713A7A3E4535"}}
{"primaryAccession": "P86399", "text": "This is Neurotoxin lambda-MeuTx protein, from Lesser Asian scorpion, contains 64 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86399", "organism_name": "Lesser Asian scorpion", "protein_name": "Neurotoxin lambda-MeuTx", "length": 64, "firstPublicDate": "2010-11-30", "FUNCTION": "Voltage-gated potassium channel (Kv) inhibitor (Ref,2), In addition it may increase intracellular calcium release through the activation of nuclear inositol 1,4,5-trisphosphate receptors (ITPR) of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the scorpion calcin-like family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSTFIVVFLLLTAILCHAEHAIDETARGCNRLNKKCNSDADCCRYGERCISTGVNYYCRPDFGP", "length": 64, "molWeight": 7177, "crc64": "889343B1FE72069F", "md5": "AEE9BE75A84667879ECDDD6B0551A7F5"}}
{"primaryAccession": "P86413", "text": "This is Protein odd-skipped-related 1 protein, from African clawed frog, contains 259 amino acids, has 3 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [168, 190], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [196, 218], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [224, 246], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "P86413", "organism_name": "African clawed frog", "protein_name": "Protein odd-skipped-related 1", "length": 259, "firstPublicDate": "2010-01-19", "FUNCTION": "Transcriptional repressor, Required for pronephric kidney development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Odd C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 3}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGSKTLPAPVPIHPSLQLTNYSFLQAFNGLPVPAEHVPNLYGFSALHAVHLHQWTLGYPTLHLPRSSFSKVPGVSSLVDSRFQIPTFPLFPHMIHPKQESPNLSNKTKPRFDFANLAVAATQEDHCKLGLMNDQGSPPAMGGLLDVTKLTPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHTQVKELKPSKIKC", "length": 259, "molWeight": 29418, "crc64": "B6E57E798FD8C116", "md5": "FFB6D4A77D88304B573317938D12DE93"}}
{"primaryAccession": "P86500", "text": "This is Conotoxin p21a protein, from Purple cone, contains 83 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86500", "organism_name": "Purple cone", "protein_name": "Conotoxin p21a", "length": 83, "firstPublicDate": "2010-06-15", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "FELLPSQDRSCCIQKTLECLENYPGQASQRAHYCQQDATTNCPDTYYFGCCPGYATCMSINAGNNVRSAFDKCINRLCFDPGH", "length": 83, "molWeight": 9299, "crc64": "F3AFE939DE4153CD", "md5": "9FD86F0F4DAC6E6D707837622FEA9DC8"}}
{"primaryAccession": "P87262", "text": "This is Large ribosomal subunit protein eL34A protein, from Baker's yeast, contains 121 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P87262", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein eL34A", "length": 121, "firstPublicDate": "1998-12-15", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eL34 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAQRVTFRRRNPYNTRSNKIKVVKTPGGILRAQHVKKLATRPKCGDCGSALQGISTLRPRQYATVSKTHKTVSRAYGGSRCANCVKERIIRAFLIEEQKIVKKVVKEQTEAAKKSEKKAKK", "length": 121, "molWeight": 13639, "crc64": "F3315816CD85ACEA", "md5": "FC36731FD73875C4D93C441400B7CF1C"}}
{"primaryAccession": "P92935", "text": "This is ADP,ATP carrier protein 2, chloroplastic protein, from Mouse-ear cress, contains 618 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P92935", "organism_name": "Mouse-ear cress", "protein_name": "ADP,ATP carrier protein 2, chloroplastic", "length": 618, "firstPublicDate": "2000-05-30", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the ADP/ATP translocase tlc (TC 2,A,12,2) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEGLIQTRGILSLPAKPIGVRRLLQPSHGLKQRLFTTNLPALSLSSNGHKKFQAFQQIPLGISVSHKERSRGFICKAEAAAAGGGNVFDEGDTAAMAVSPKIFGVEVTTLKKIVPLGLMFFCILFNYTILRDTKDVLVVTAKGSSAEIIPFLKTWVNLPMAIGFMLLYTKLSNVLSKKALFYTVIVPFIVYFGAFGFVMYPLSNLIHPEALADKLLATLGPRFMGPLAIMRIWSFCLFYVMAELWGSVVVSVLFWGFANQITTVDEAKKFYPLFGLGANVALIFSGRTVKYFSNMRKNLGPGVDGWAVSLKAMMSIVVGMGLAICFLYWWVNRYVPLPTRSKKKKVKPQMGTMESLKFLVSSPYIRDLATLVVAYGISINLVEVTWKSKLKAQFPSPNEYSAFMGDFSTCTGIATFTMMLLSQYVFKKYGWGVAAKITPTVLLLTGVAFFSLILFGGPFAPLVAKLGMTPLLAAVYVGALQNIFSKSAKYSLFDPCKEMAYIPLDEDTKVKGKAAIDVVCNPLGKSGGALIQQFMILTFGSLANSTPYLGVILLGIVTAWLAAAKSLEGQFNTLMSEEELEREMERASSVKIPVVSQEDAPSGETTSQLSEKSTPTGI", "length": 618, "molWeight": 67530, "crc64": "B2D49E77F17A887A", "md5": "94E127B506CA364E8B849D82A77478D4"}}
{"primaryAccession": "Q02614", "text": "This is SAP30-binding protein protein, from Mouse, contains 308 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02614", "organism_name": "Mouse", "protein_name": "SAP30-binding protein", "length": 308, "firstPublicDate": "1994-02-01", "FUNCTION": "Plays a role in transcriptional repression by promoting histone deacetylase activity, leading to deacetylation of histone H3 (By similarity), May be involved in the regulation of beta-2-microglobulin genes (PubMed:1459361)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the HCNGP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGKKNVLSSLAIYAEYSDPESDGETGVDAVGGATEEKGGLVSDAYGEDDFSRPGGDEDGYEEEEDENSKQSEDDDSETEKPEADDPKDNTEAEKRDPQELVASFSERVRNMSPDEIKIPPEPPGRCSNHLQDKIQKLYERKIKEGMDMNYIIQRKKEFRNPSIYEKLIQFCAIDELGTNYPKDMFDPHGWSEDSYYEALAKAQKIEMDKLEKAKKERTKIEFVTGTKKGTTTNATATSTSTASTAVADAQKRKSKWDSAIPVTTIAQPTILTTTATLPAVVTVTTSASGSKTTVISAVGTIVKKAKQ", "length": 308, "molWeight": 33832, "crc64": "4E36A6A4B58098FB", "md5": "40FB0D0F7A87FD4BFA5D6E54B212AC87"}}
{"primaryAccession": "Q03218", "text": "This is Mitochondrial metal transporter 1 protein, from Baker's yeast, contains 510 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03218", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial metal transporter 1", "length": 510, "firstPublicDate": "1997-11-01", "FUNCTION": "Mitochondrial metal transporter involved in mitochondrial iron accumulation", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the cation diffusion facilitator (CDF) transporter (TC 2,A,4) family, SLC30A subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLRICVKRPCIKIVLSQVRPALLVRKENLHISTGVKVEKSSIINQKDPNKVRVEINELKRQAEIEKAAIKELEKNPQYQKLAEAFNSHDHVHLRESETEQNDIISLGTIRDYKSSKCEQADKPSSLNLHSHTHSHGHTHSHAAHNPLLVLSTEQIRKNAGVRITWVGLGVNVGIAIGKFFGGIVFHSQALFADAIHAISDMVSDLLTLLSVGLAANKPTADYPYGYGKIETVGSLAVSTILAMAGISIGWSSLCALVGPVIPHTIIDTIGNLGHAHTYSEDIIEDVTDINAAWIAAASIAAKEWIFRATRKIAINTNSNVLMANAWHHRVDSLTSLVALVAISTGYLVNIQSLDTIGGLIVSGLIIKAGGEGMCIAIKELIDQSVSRDDPRYLEIETLVKDTLNKLISNNNSQKPYGLKELTLLSSGPNLRGHLTLEVPLQKWGNILGVNEFEIVTHHLRNVLTNEVSNLRRLDIEYVEEKNGEENEHIKGQQNYKEDVLIKHDHTNTHI", "length": 510, "molWeight": 56209, "crc64": "F3CC9A230FB5DB87", "md5": "CC89DB187BA9329D038DC8699EA2C059"}}
{"primaryAccession": "Q03266", "text": "This is Aminodeoxychorismate lyase protein, from Baker's yeast, contains 374 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03266", "organism_name": "Baker's yeast", "protein_name": "Aminodeoxychorismate lyase", "length": 374, "firstPublicDate": "1997-11-01", "FUNCTION": "Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSLMDNWKTDMESYDEGGLVANPNFEVLATFRYDPGFARQSASKKEIFETPDPRLGLRDEDIRQQIINEDYSSYLRVREVNSGGDLLENIQHPDAWKHDCKTIVCQRVEDMLQVIYERFFLLDEQYQRIRIALSYFKIDFSTSLNDLLKLLVENLINCKEGNSEYHEKIQKMINERQCYKMRVLVSKTGDIRIEAIPMPMEPILKLTTDYDSVSTYFIKTMLNGFLIDSTINWDVVVSSEPLNASAFTSFKTTSRDHYARARVRMQTAINNLRGSEPTSSVSQCEILFSNKSGLLMEGSITNVAVIQKDPNGSKKYVTPRLATGCLCGTMRHYLLRLGLIEEGDIDIGSLTVGNEVLLFNGVMGCIKGTVKTKY", "length": 374, "molWeight": 42640, "crc64": "560B9757F6BBBB73", "md5": "1291CDCB41C67B1661F4B5DB92566CA0"}}
{"primaryAccession": "Q03652", "text": "This is Protein DML1 protein, from Baker's yeast, contains 475 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03652", "organism_name": "Baker's yeast", "protein_name": "Protein DML1", "length": 475, "firstPublicDate": "1997-11-01", "FUNCTION": "Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the misato family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MHEVVTISVSQRANHLTTQFFNIQEGYLQLSKEQQVNDSKIFLNSVVDKVSKTISYAPRALLWDARTGNGSLGTYQYSESQDYHFGNEDKFKEQTVIKTHPRIPKSEYQSSLDAGAPLPCLNRENTMYWSDYSKLIYGPSSFNILRNWYHDTENPNQPDFQNLGERKFDRYSIGYDEFTENYLQEFFDGNLHRELEKCDTLQGFNLVSDMESGWGGFSSALLVELRNELPKKAVFSWGHNEDDPFTDDFPMKRLSKKWLPIISNKLRSTINMMQESDLYFPLYAAPGLTNWETAGKSCRIFDSINATISQSNLEQRKTMDYLTTAITLGYSSRNMVTGMVIGDTDYSFCSRVLPFKNSHKPNSTHIFSKSFIDRGNQTHKHHSEPDSRSKMIEMYTHRYFPSDTIPTEFSNDREFVLELESSEKNRDIFKHWNEFVVRYFKNDSDREELKNELSDYASAYESGWYEDEDSGDDDM", "length": 475, "molWeight": 55312, "crc64": "A24CA4E6BA9DC146", "md5": "4C53B89452B3828C8B974B4B00223824"}}
{"primaryAccession": "Q03673", "text": "This is Altered inheritance of mitochondria protein 34, mitochondrial protein, from Baker's yeast, contains 198 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03673", "organism_name": "Baker's yeast", "protein_name": "Altered inheritance of mitochondria protein 34, mitochondrial", "length": 198, "firstPublicDate": "1997-11-01", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the AIM34 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSISLLGRIVSQQFSGIRAAEPGRSLYLPFTLLLKQPGAYKVSLHRYVHSTQTKSHLSFLMNNNDITPFQKFTVKVLKEQCKSRGLKLSGRKSDLLQRLITHDSCSNKKSSVKINEPKKKRILINDPIKITKKLVSDKTFRTIEKNISSLQNTPVIETPCDVHSHLQPRDRIFLLGFFMLSCLWWNLEPQESKPTIDH", "length": 198, "molWeight": 22742, "crc64": "CBA09B4FE5BBA795", "md5": "1B05A55A91322A247EF055CCD7234C37"}}
{"primaryAccession": "Q04031", "text": "This is Ribosomal RNA-processing protein 17 protein, from Baker's yeast, contains 235 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q04031", "organism_name": "Baker's yeast", "protein_name": "Ribosomal RNA-processing protein 17", "length": 235, "firstPublicDate": "2006-10-17", "FUNCTION": "Essential protein involved in ribosomal RNA processing", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the RRP17 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAVHTNRQILTRGKNYATKQSKKFGTDEVTFDKDSRLDYLTGFHKRKLQRQKKAQEFIKEQERLRKIEERQKIRQERKEVMEEQLKTFKESLNLEAEIEDAKNDKTEDLQVESDESWHGFDSDKDDGDNDNNESSVKPILKKGAITEIYDDSTTVELETLEPNDNFEYLAQLNNVKLEKAEKVLKQSINRATKYAKFLGVDEKQKKKPRVKKFRYLTKNERRINQRKANDNKRRR", "length": 235, "molWeight": 27974, "crc64": "A61BB3AE3838CBAF", "md5": "310CA91881C0231FC2F04A73785DFE39"}}
{"primaryAccession": "Q04341", "text": "This is Mitochondrial intermembrane space cysteine motif-containing protein MIX14 protein, from Baker's yeast, contains 121 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q04341", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial intermembrane space cysteine motif-containing protein MIX14", "length": 121, "firstPublicDate": "2006-06-27", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSDILDEIVIEDVVANCPQEFLQYHKCIRDNEENPGKCKDGRMILSTCIREKVPSVKSIMSECSEPMKKYDQCIRDNMGTRTINENCLGFLQDLRKCAELQVKNKNIKPSINGVNLELIKD", "length": 121, "molWeight": 13866, "crc64": "9502632E07FC7916", "md5": "B17ED211677510239D166AFDDA0C9D6C"}}
{"primaryAccession": "Q04806", "text": "This is Glutathione S-transferase omega-like 3 protein, from Baker's yeast, contains 366 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q04806", "organism_name": "Baker's yeast", "protein_name": "Glutathione S-transferase omega-like 3", "length": 366, "firstPublicDate": "1997-11-01", "FUNCTION": "Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the GST superfamily, Omega family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSEKSASNNKAEFKRQSSPFREIISADHPIYKPAKGRYWLYVALPCPWAQRTLITRALKGLAPIIGCSVAHWHLDDKGWRFLEEGDGKTNERHWFDIAGGISSVNLNTSTPVANIPNNAHRLLVDGTDEPHYGYKRLSDFYFKTKPDYKGRFTVPVLWDLETCTIVNNESSDIIGIMNSAAFDEFVGEEYRQVRLVPRSLEAQITEFNSWVYDKINNGVYKAGFAECAEVYEREVTSLFQYLDKLENLLDKKYTDLEAEYGKNNKDKILDRYFAIGDTLTEADVRLYPTIVRFDVVYHQHFKCNLATIRDDYSRIHTWLKNIYWRHEAFQRTTDFTHIKLGYTRSQPRVNPIGITPLGPKPDIRPP", "length": 366, "molWeight": 42403, "crc64": "C0BF9F2D3AB5C15B", "md5": "55162D7243DB0B91FB9162AC1F365796"}}
{"primaryAccession": "Q04949", "text": "This is Cytoplasmic dynein intermediate light chain DYN3 protein, from Baker's yeast, contains 312 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q04949", "organism_name": "Baker's yeast", "protein_name": "Cytoplasmic dynein intermediate light chain DYN3", "length": 312, "firstPublicDate": "1997-11-01", "FUNCTION": "Component of the cytoplasmic dynein which acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules, May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast, Probably required for normal progression of the cell cycle", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the dynein light intermediate chain DYN3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDNCNAWDKLLSQNESTINSTETATITAIIYSPSSKTLHQFINICFPEGSNSILDTTLINYATIGWTNDLKENYSVDVYTLIRNTDDALDLLKPFLQEHSSKVRWLILLDWTLNDQKLWLNELSYAFNKIKQLNDDNEFSVWCLNSGEILNLQRHTTVWQSVHIDFILQTLRSFCYFNDSSLFYICEDHTEEKREEAQRLKYQELLKHFCEDRDMKDHIEMVKRSEILIPKGCDSIGLIKTVDERFEPTEVKEQHFLARYMDFIPTIDKIREDRKTTSGIDLDKLYPLEVFKVNIQEELGKMFAKYRENSRI", "length": 312, "molWeight": 36825, "crc64": "BFDEC080E08602A2", "md5": "C83898B1E61F97CEDA14CBB718764B6F"}}
{"primaryAccession": "Q05394", "text": "This is fMet-Leu-Phe receptor protein, from Rabbit, contains 352 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05394", "organism_name": "Rabbit", "protein_name": "fMet-Leu-Phe receptor", "length": 352, "firstPublicDate": "1994-02-01", "FUNCTION": "High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors, Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release, This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system, Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release (By similarity), Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis (By similarity)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDSNASLPLNVSGGTQATPAGLVVLDVFSYLILVVTFVLGVLGNGLVIWVTGFRMTHTVTTISYLNLALADFSFTSTLPFFIVTKALGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCICVLHPVWAQNHRNVSLAKKVIVGPWICALLLTLPVIIRVTTLSHPRAPGKMACTFDWSPWTEDPAEKLKVAISMFMVRGIIRFIIGFSTPMSIVAVCYGLIATKIHRQGLIKSSRPLRVLSFVVASFLLCWSPYQIAALIATVRIRELLLGMGKDLRIVLDVTSFVAFFNSCLNPMLYVFMGQDFRERLIHSLPASLERALSEDSAQTSDTGTNSTSAPAEAELQAI", "length": 352, "molWeight": 38675, "crc64": "51DA550DAB13A091", "md5": "14FE29B2CBEA328D8661FE6B0B2811DF"}}
{"primaryAccession": "Q06188", "text": "This is PWWP domain-containing protein YLR455W protein, from Baker's yeast, contains 304 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06188", "organism_name": "Baker's yeast", "protein_name": "PWWP domain-containing protein YLR455W", "length": 304, "firstPublicDate": "2006-07-25", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTKDIRTGDLVLCKVGSFPPWPAVVFPQRLLRNDVYRKRKSNCVAVCFFNDPTYYWEQPSRLKELDQDSIHNFILEHSKNANQRELVNAYKEAKNFDDFNVFLQEKFEEENRLSDLKAFEKSEGSKIVAGEDPFVGRTKVVNKRKKNSISIKEDPEDNQKSNEEESKPNIKPSKKKRPTANSGGKSNSGNKKKVKLDYSRRVEISQLFRRRIQRNLIQRETPPTEHEIKETHELLNRIYENSDTKRPFFDLKALRESKLHKLLKAIVNDPDLGEFHPLCKEILLSWADLITELKKEKLQALPTP", "length": 304, "molWeight": 35508, "crc64": "4FDEF7A7AB69C96D", "md5": "27F6C583DCCB2BACE5BD15AEB17ECA27"}}
{"primaryAccession": "Q06678", "text": "This is Large ribosomal subunit protein mL38 protein, from Baker's yeast, contains 367 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06678", "organism_name": "Baker's yeast", "protein_name": "Large ribosomal subunit protein mL38", "length": 367, "firstPublicDate": "2004-04-26", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the phosphatidylethanolamine-binding protein family, Mitochondrion-specific ribosomal protein mL38 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRRSIHTTKILQKPNATSHIWSDFTTRPSSLSIQSSKVKNYLFQKKASLDPPSISRRSNRIKYSPPEHIDEIFRMSYDFLEQRSSKFYELANKTKNPLKKDALLIKAEINNPEVQYNFQFNNKLNNVKDIIDYDVPVYRHLGKQHWESYGQMLLMQRLETLAAIPDTLPTLVPRAEVNIKFPFSTGVNKWIEPGEFLSSNVTSMRPIFKIQEYELVNVEKQLYTVLIVNPDVPDLSNDSFKTALCYGLVNINLTYNDNLIDPRKFHSSNIIADYLPPVPEKNAGKQRFVVWVFRQPLIEDKQGPNMLEIDRKELSRDDFDIRQFTKKYNLTAIGAHIWRSEWDAKVAAVREKYGLPPGRVFSRVRR", "length": 367, "molWeight": 42825, "crc64": "C6A2C973121FF555", "md5": "96418C0681448B0496AC63E78FB10AE0"}}
{"primaryAccession": "Q06688", "text": "This is SRR1-like protein BER1 protein, from Baker's yeast, contains 274 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06688", "organism_name": "Baker's yeast", "protein_name": "SRR1-like protein BER1", "length": 274, "firstPublicDate": "2003-05-30", "FUNCTION": "Involved in microtubule stability and kinetochore function, May be involved in protein N-terminus acetylation and/or proteasome biogenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the SRR1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDFKASGTKFKKTGKKVVPAKAFEEIVQTNRDVLKKSAFLSDLLENLQPHLNNIKKIRCVAIGNFKEDFPATYQFALLLEITDYIKSEDERDVVVSLYDPIFTKEEIQYLKSLGSKWLIEEEFSENDAIDYESVLYFLPHAPLDLTENILSSQRPHLWLANNMISHTDRYTKAKLCENYPNLSKLVHYLQTNAPPEVKKAHDVDGFATFIPKRKRKNRNNSSKLKVTPSDIDYDSIAPKFKSCQILTDFDEGKYLKEKPWINSFSDLTLHAIEY", "length": 274, "molWeight": 31707, "crc64": "1B9FBC82F970946A", "md5": "5C6CA8D7C4C036ACD1F63ADCFBADB46D"}}
{"primaryAccession": "Q07230", "text": "This is Zinc finger and SCAN domain-containing protein 2 protein, from Mouse, contains 614 amino acids, has 14 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [222, 244], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [250, 272], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [278, 300], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [306, 328], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [334, 356], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [362, 384], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [390, 412], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [418, 440], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [446, 468], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [474, 496], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [502, 524], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [530, 552], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [558, 580], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [586, 608], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q07230", "organism_name": "Mouse", "protein_name": "Zinc finger and SCAN domain-containing protein 2", "length": 614, "firstPublicDate": "1998-07-15", "FUNCTION": "May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the krueppel C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 14}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAEVPAVSTPLSPLVQVPQEEDEQAEVTTMILEDDAWVQEAVLQEDGPESEPFPQSAGKGSPQEEDAAEGPQGALVRFRELCRRWLRPEVHTKEQMLTVLPREIQAWLQEHRPESSEEAVALVEDLTQTFRHSDFEIQSENGENSNEDMFEGVESHGMFLNISGGEGGQQSDGDSDFERDCGSGGAQGHAPGEDPRVVPSEGREVGQLIGLQGTYLGEKPYECPQCGKTFSRKSHLITHERTHTGEKYYKCDECGKSFSDGSNFSRHQTTHTGEKPYKCRDCGKSFSRSANLITHQRIHTGEKPFQCAECGKSFSRSPNLIAHQRTHTGEKPYSCPECGKSFGNRSSLNTHQGIHTGEKPYACKECGESFSYNSNLIRHQRIHTGEKPYKCTECGQKFSQSSALITHRRTHTGEKPYQCGECGKNFSRSSNLATHRRTHLVEKPYKCGLCGKSFSQSSSLIAHQGTHTGEKPYECLTCGESFSWSSNLIKHQRTHTGEKPYRCGDCGKGFSQRSQLVVHQRTHTGEKPYKCLMCGKSFSRGSILVMHQRAHLGDKPYRCPECGKGFSWNSVLIIHQRIHTGEKPYRCPECGKGFSNSSNFITHQRTHLKEKLY", "length": 614, "molWeight": 68714, "crc64": "738156A0A9413DF7", "md5": "33B524C83A7312D1CDFE082ECB37E610"}}
{"primaryAccession": "Q07376", "text": "This is Probable transporter MCH1 protein, from Baker's yeast, contains 486 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q07376", "organism_name": "Baker's yeast", "protein_name": "Probable transporter MCH1", "length": 486, "firstPublicDate": "2005-10-25", "FUNCTION": "Probable transporter, Does not act in the transport of monocarboxylic acids across the plasma membrane", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the major facilitator superfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPLSKVEHYLSYHTRLLLPHVLSLQSSHRVAYIFSLLSAVSTGFITLISLYSQPWQKHLNYSSWQINTIASMTNLGMYLTPPILGMIADSHGPITLSLLAIIGFIPSYSYLAYVFNHPELSLGGNGDSSFNLSIICFVFIGISTSALYFSALLTCTKLYPHTKLLSISLPTTCYGISSVVGSQLLRIKWFWSSNASSSSSNSDLNLGRVFQTFALVYVVIGLLAWIATSVVSLLHFNEEQDNQKRLDDQTDVEQSPLLERSNHVQEKFTQTMLRIFSDPVTYILAVSILLSLGPLEMFIANMGSLTNLLVQLDAPTLSTKLLSTYALSSTFTRLLTGIVADFFAKKKISIKWILLTFLSLGVCAQLFLLKMTSSASPWGLVPTGSLVGIVYGGLFTVYPTLVLLVWGERSFGTVYGSLLIAPAIGSMIFCMLYAKFYDSRCMSGGGDLRNPSCISAVYKYSSIAFVVSAVLSAVVFWKLKSRKLRI", "length": 486, "molWeight": 53566, "crc64": "F233A3FE854C53DB", "md5": "CE9DC22329855CC346C5D5CE8CAF448D"}}
{"primaryAccession": "Q07549", "text": "This is Protein SNA4 protein, from Baker's yeast, contains 140 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q07549", "organism_name": "Baker's yeast", "protein_name": "Protein SNA4", "length": 140, "firstPublicDate": "1998-07-15", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the UPF0057 (PMP3) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MCCYCVCCTVSDFILYIVAFFFPPAAVLLRSGPCSSDFLLNVLLTLLGFLPGMLHAFYYITITSPLRNAEYVYYYQQGWVDSERNVPSNRPQNSQTPQNRPQQGSSARNVYPSVETPLLQGAAPHDNKQSLVESPPPYVP", "length": 140, "molWeight": 15673, "crc64": "3B9378FD5EDDFA5A", "md5": "CF41AB93B9702902818A024546224BB4"}}
{"primaryAccession": "Q08553", "text": "This is Protein SYC1 protein, from Baker's yeast, contains 188 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08553", "organism_name": "Baker's yeast", "protein_name": "Protein SYC1", "length": 188, "firstPublicDate": "2006-01-10", "FUNCTION": "Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB, Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation, including snoRNAs and snRNAs", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDLPKDKSDRTHQRINLNNSGTDRTNDLYLHIVQTFGCIETTATENATKLLMLGDVEVEISASSVSIEWTQKSMISQTIADSIVIMIIGLCASDKNVLSESELKERNHNVWKIQELQNLFREQFGDSFSIDEGIGKKENVKNGSVTIGKSKATIDFSTMKLIDCNSNPLKGRVESILSIGQKLTTPLC", "length": 188, "molWeight": 20866, "crc64": "6FB2B030A983065D", "md5": "1E7A4A2D7C96A11D9B204D05EA386038"}}
{"primaryAccession": "Q09146", "text": "This is Brefeldin A resistance protein protein, from Fission yeast, contains 399 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09146", "organism_name": "Fission yeast", "protein_name": "Brefeldin A resistance protein", "length": 399, "firstPublicDate": "2001-08-29", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTSKMENNKDESISTKNALEEKSNETKDETSKRKHDPAEEESAVSTKVSKSEPLEDKGNAEVKEFKETTKSNGVKPEVEITESTKIQKESNTEPCISTGGKVEEKELKVNKDVDENEGHVAVETGKKESAAKPAASVSPFSQFASFSNASSPFSNVSTASSEPKEEKSAFGAFASSKSAFTMKSVKDSPFKKFAAGTAVETESGSGKEKENDKKSSENFDELLANTSAKAFENQKGSAGETKSEPKEADKGSGDSTKSTMHQLSDSEIITGEEEEESIFSVRARLYVVADEKKTWKERGQGILKVNVPKQRGSGSGRLLMRNDAVHRVIMNVPLFQGMSKKSLQIASASSGGSANYLKIFVIENGKSVLYAVRVKDNSLAEQLRNHVLEAIPKGGREDA", "length": 399, "molWeight": 43201, "crc64": "52F5A03F0020ACEE", "md5": "16EF15DA3A98E4904C5DE35E7E22605E"}}
{"primaryAccession": "Q09781", "text": "This is Small ribosomal subunit protein eS1A protein, from Fission yeast, contains 252 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09781", "organism_name": "Fission yeast", "protein_name": "Small ribosomal subunit protein eS1A", "length": 252, "firstPublicDate": "1995-11-01", "FUNCTION": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the eukaryotic ribosomal protein eS1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAVGKNKRLSKGKKGIKKRVVDPFSRKDWYDIKAPAFFEVKNVGKTLVNRTAGLKNANDSLKGRILEVSLADLQKDEEHSFRKVKLRVEDIQGKSCLTSFNGFDMTSDKLRSLVRKWQSTIEANQTIKTTDGYLCRIFVIGFTSRRVNQVKKTTYAQSSQIRAIHQKMFQVIQNQANGCSMKELVQKLIPEVIGRAIEKATNNIYPLQNVFVRKVKILKAPKHDAQKLLELHGESQDVGSKVISDVAPLESV", "length": 252, "molWeight": 28488, "crc64": "B3254B71785A9BB3", "md5": "91463654B6070E4E7763EE7B37E5DF18"}}
{"primaryAccession": "Q09842", "text": "This is PWWP domain-containing protein 3 protein, from Fission yeast, contains 407 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09842", "organism_name": "Fission yeast", "protein_name": "PWWP domain-containing protein 3", "length": 407, "firstPublicDate": "1996-02-01", "FUNCTION": "Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 acetylation (H3K14ac), critical for DNA damage checkpoint activation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMVARTRSQKRKLEEINNQKKIKTKKKATGQQTSNTKNLRDVKKKGKQLAYVPRTSPRKSYKNGEYVLAKMSSFPWWPARVASQKSIPTEVRERLKRNFRMDNGIFVQFLPSRDYAIISSSNVLPLTVDESRFILDHDLSTKYIQKTVGLIIASVKRKVSFSDVEEDEFEPENTRKKLQKPIEKPKKEKIEATPKIDGGKRLKNEKSSAEISQTSKQRPSRRSARVRMATDNAQKSPSPIPSPKKTAKKRVRFAGSLEELPKFSLEYQLAQPISTVDMYAQVHYIRFNTLLYYRYQLQEILLSYNHYPQESDMSHVHQILEMIENFSAINSELLESTKLYSLFTLLVKLSDIPLDEKYDFSSRFSTLLLQFQAFVQPKTMTSNVSTAPIGKNAQVNTEAARPSVITT", "length": 407, "molWeight": 46856, "crc64": "CBB82BD5CA78A028", "md5": "CC225E3B05A798233A013C5DD7921B75"}}
{"primaryAccession": "Q09GJ9", "text": "This is Cysteine-rich venom protein protein, from Green snake, contains 239 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09GJ9", "organism_name": "Green snake", "protein_name": "Cysteine-rich venom protein", "length": 239, "firstPublicDate": "2008-01-15", "FUNCTION": "Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction, May target voltage-gated calcium channels on smooth muscle (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the CRISP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIVFILLSLAAVLQQSFGLVDFNSESPRRPEIQRVIVDTHNSYRRTVSPTASNMLRMEWYAEAAANAERWASLCAYDHSQNSDRVLDGIQCGENIYMSSNPRSWTEIMQSWYDEYKNFDFGYGANPPGSVIGHYTQIVWYKSYRIGCAAYYCPSSLYNYFYVCQYCPAGNFAGRTATPYNSGPTCGDCPSACDNGLCTNPCSEKNEFTNCNELVQQSSCQDDWIKSNCAATCFCKNKII", "length": 239, "molWeight": 26968, "crc64": "A835CB372EAD7569", "md5": "5CA03A7F7E970D27D086FEE4E8C8916A"}}
{"primaryAccession": "Q0DFC9", "text": "This is Plastocyanin, chloroplastic protein, from Rice, contains 154 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q0DFC9", "organism_name": "Rice", "protein_name": "Plastocyanin, chloroplastic", "length": 154, "firstPublicDate": "2007-07-10", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAALSSAAVTIPSMAPSAPGRRRMRSSLVVRASLGKAAGAAAVAVAASAMLAGGAMAQEVLLGANGGVLVFEPNDFTVKSGETITFKNNAGFPHNVVFDEDAVPSGVDVSKISQEEYLNAPGETFSVTLTVPGTYGFYCEPHAGAGMVGKVTVN", "length": 154, "molWeight": 15577, "crc64": "E45725D25B5F400D", "md5": "9AFA3C7D6C4449AC70169E9E2943EF5E"}}
{"primaryAccession": "Q10154", "text": "This is Replication termination factor 2 protein, from Fission yeast, contains 240 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10154", "organism_name": "Fission yeast", "protein_name": "Replication termination factor 2", "length": 240, "firstPublicDate": "1996-10-01", "FUNCTION": "Replication termination factor which mediates replication termination at the site-specific replication barrier RTS1, Stabilizes the replication fork stalled at RTS1 until completion of DNA synthesis by a converging replication fork initiated at a flanking origin", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the rtf2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGNDGGSLPTRNELVKEPGKVPPLDIDFKRSVKSSQFSQCAITDEPLYPPIVSCGLGKLYNKASILQMLLDRSSVPKSPSHIKSLKDVVQLQVELDDSGKVLWLCPITRHVMSDTYQFAYIVPCGHVFEYSALKQFGEKMCFQCNQVYEEKDVIPINPNAEQLKTLSKRLLDLALSEKTHSLNKASKKSNKNGDKKRKHVSKSNSKHAKHELRTNRMLDGENVKSETSVTDMERVKRVKI", "length": 240, "molWeight": 27057, "crc64": "6C05265CE64DD889", "md5": "7062CF13D054183B2BE95196E81C428A"}}
{"primaryAccession": "Q10297", "text": "This is Importin subunit beta-5 protein, from Fission yeast, contains 993 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10297", "organism_name": "Fission yeast", "protein_name": "Importin subunit beta-5", "length": 993, "firstPublicDate": "1996-10-01", "FUNCTION": "Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins, Serves a receptor for nuclear localization signals, Mediates the nuclear import of TATA-binding protein (TBP) and of histones H2A and H2B (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVESKIIKLLEQVQSADPNSRIQAELGLRDLEKYHDFAAKLTDIASSGASVPLRQGSLIYLQRYIVHHWSPLFEQFQDGPIPDENVKKHVRETLLHLLVSLDNFTLIKAVAYAVSLIANVDYPDEWPEVVPAVLHLLQSTNENSINASLDVLDELVDESLVEEQFFIIAPQLASILYQFIFSAPPNDSMRMLQARGIKLFRSCLELIEIYKETKAEHVRVFLEQILPPWMDMFSHKFEVSLVDDRQVILPDSCGYFCIMGEIAMTLTKLRELFPSKLTPYVVTFVELVWNIIEKLLDPYIREVVFSDGLDDSAFGDKYPIRYLVELLLFVSVALQSKFVQNLFVSNTVPVPPLPPCIPLLVQYTQLPKHQIEVYESDVSEYIANEFSMDFASDTVRGAAISVLSAFEEHTTLPIQQSLREMSATYILNNEINWIYQEALLYACCSVDAASDDTYDDYLDPIYEAIKVRIDYSDAPILLLSRFFLFIGYFSESTVVASQFFQIIMNNLVNALQVDTVQYAAMKAIERFCSVGKVKPILSLQPMILEVLSQYASKSSDEALVLLVEAISSAVKLDCAKAAELGNSVIPLLFNLVATNASDPYICGIIEDTFEDIIHAANNYESMCEITLPELLQVLNQEDPIMVNIGATLLSCLIRAGPSPLPNGFVGYVLPPVYKITQIHSGDTELLQLSQEILKGLLEKDTPQLLETEISGSSGFQYILFILHQLLDKESDDSACFLVGPILLELADHASQMVDLQSILLSCIKRLAIAEQPRFIQSIIYVFAKLIVKDSLGMMHFLTSSLLNEQGLTAFEVLMTVWCDNFVYFSNFKNISIICIAMTKIYSFDSPLLDSVQVKGELISHSNRIITRSQSKLHPEEYSYVSVGEKILRLLSEEFVSLSKDAIVEEVSDDGADDWDDGPISAETFGLSANDVNELSKDEFSGVDNSEDEDNTDLQFYLLEFFKEAMKSNLHNINEVVFRLPQEEQDALVQIKEK", "length": 993, "molWeight": 111864, "crc64": "A1D63EFD6EAC2098", "md5": "62843124093B9323DBFF8F9CAF01CC54"}}
{"primaryAccession": "Q12251", "text": "This is Uncharacterized mitochondrial carrier YPR011C protein, from Baker's yeast, contains 326 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12251", "organism_name": "Baker's yeast", "protein_name": "Uncharacterized mitochondrial carrier YPR011C", "length": 326, "firstPublicDate": "2006-06-27", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAEVLTVLEQPNSIKDFLKQDSNIAFLAGGVAGAVSRTVVSPFERVKILLQVQSSTTSYNRGIFSSIRQVYHEEGTKGLFRGNGLNCIRIFPYSAVQFVVYEACKKKLFHVNGNNGQEQLTNTQRLFSGALCGGCSVVATYPLDLIKTRLSIQTANLSSLNRSKAKSISKPPGIWQLLSETYRLEGGLRGLYRGVWPTSLGVVPYVALNFAVYEQLREFGVNSSDAQPSWKSNLYKLTIGAISGGVAQTITYPFDLLRRRFQVLAMGGNELGFRYTSVWDALVTIGRAEGVSGYYKGLAANLFKVVPSTAVSWLVYEVVCDSVRNW", "length": 326, "molWeight": 35913, "crc64": "317D4CD8041F4A21", "md5": "765EBD65440305046ECC72FF57CDA721"}}
{"primaryAccession": "Q12288", "text": "This is Putative glutamine amidotransferase YLR126C protein, from Baker's yeast, contains 251 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12288", "organism_name": "Baker's yeast", "protein_name": "Putative glutamine amidotransferase YLR126C", "length": 251, "firstPublicDate": "2006-07-25", "FUNCTION": "May have a role in copper and iron homeostasis", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTVKKIAILYTDEDNEWSKPWGNFVDMAIKLLEQTRKLECIAEDVEYEVFHVQKNVFPQLSDLQKDEYLGIYITGSKYDSFDNEIEWIMKLRSFLNEMLTSKTEYPPVAGICFGHQVIAAALGSSVGRNPKGFEGGVVSLKLNSVGQKLFGAQELNLSEVHSDCVFDVPEGYQNWASSEKCQNQGFYRQNRVLTFQGHPEFNSDVAQKGLLKSQDKLTLEEFNRYERQCQELDNNGIQAARNIWRLFLQKI", "length": 251, "molWeight": 28826, "crc64": "FCC96A8B62880D5C", "md5": "4EC64588991764431E3BA3D3B058E819"}}
{"primaryAccession": "Q12454", "text": "This is Putative tyrosine-protein phosphatase OCA6 protein, from Baker's yeast, contains 224 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12454", "organism_name": "Baker's yeast", "protein_name": "Putative tyrosine-protein phosphatase OCA6", "length": 224, "firstPublicDate": "2006-06-27", "FUNCTION": "Required for replication of Brome mosaic virus (BMV)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the protein-tyrosine phosphatase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTLVTPLQFSTVQPNLYRGSYPREINLPFLRTLRLKYILSLTPEPLSTDPLMVKFCEENNIKTIHIKCQSERKADKTKPKIKRKKKTVPIEYDVVVRCVKFLIDKGHYPCYMHCTNGELIISLVVACMRKFSYWSTVSILNEFLVYNSSINIHERNFIENFNSEIEVDDLDIKDKVPWITVRYIARTATESKDELRVDDANASEKVARVSSVSNSLPKLKFHSM", "length": 224, "molWeight": 26024, "crc64": "FFF222994B196F86", "md5": "8FB54CB864AD19FEE25286EA053D4EC9"}}
{"primaryAccession": "Q12507", "text": "This is Superficial pseudohyphal growth protein 1 protein, from Baker's yeast, contains 346 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12507", "organism_name": "Baker's yeast", "protein_name": "Superficial pseudohyphal growth protein 1", "length": 346, "firstPublicDate": "2006-12-12", "FUNCTION": "Probable transcription factor required for superficial pseudohyphal development in response to nitrogen starvation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDEMHSSDTLLLRTPKSKKKIGLVIPSTPSKKCKYSSGFIAEDTTPSKRFRLYQAKFKTSSKNVKAQTLSVSIKKNQGEITNPFMTEGYNDYRNIVSPGLSFDNDCFSEHELVSPLSDISSINSTSPDVEKIDSLDPFGVDSFVWNCKPLVNKEALELHRMIHSSFPMSPLESNSDVPLLLPKLKKRLSPVNRSTFKPTRYEPSHRLLKPKKSILTVPAKSLNLIVSSSRGSLNDATIFATEINSTLSNEENKLPAISSIWEKLTIPVNSSIKEKYKKLKDQIYGQASNFGEDEDNEEDNEDDLPDAAVIRGYEFQSGRRDELTQCNELQSTKDYKKVQWAKVLEQ", "length": 346, "molWeight": 39021, "crc64": "D7EEF4D6CDEBAD37", "md5": "A0140FE72D2815E42109A4EA629D9026"}}
{"primaryAccession": "Q12515", "text": "This is Protein PAR32 protein, from Baker's yeast, contains 295 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12515", "organism_name": "Baker's yeast", "protein_name": "Protein PAR32", "length": 295, "firstPublicDate": "2006-06-27", "FUNCTION": "Involved in resistance to cisplatin", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATFNPQNEMENQARVQEYKVSTGRGGAGNIHKSMSKPSPVLLPLKSNSKTVANNNNNGSNQEKVPRFAIGRGGAGNIFHDPHLTRSAQQLDSNDNINYNDVINDIDDYISPITSDMVDEGGSNPVTNTRSRISATRSHQSLHATTSSPNNNAPIVVGRGGAGNIFFNKKKVASNGGNEEDEIRGGNIEDEDTINANEDNLFVVTSNGNALAAIKSTSKKPKNKLKGKSAPEKFAIGRGGAGNIISPKSSRNTINHNLNDDDEDKFNLKDDNGKEKKKKKKKKSGFFSSLKTMFN", "length": 295, "molWeight": 31886, "crc64": "AF6C66D386B18705", "md5": "A32837B4E50DAEF45C6E1429C789FC9E"}}
{"primaryAccession": "Q13536", "text": "This is Protein CROC-4 protein, from Human, contains 156 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q13536", "organism_name": "Human", "protein_name": "Protein CROC-4", "length": 156, "firstPublicDate": "2008-05-20", "FUNCTION": "May play a role in FOS signaling pathways involved in development and remodeling of neurons, Promotes transcription of the FOS promoter", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFLTEDLITFNLRNFLLFQLWESSFSPGAGGFCTTLPPSFLRVDDRATSSTTDSSRAPSSPRPPGSTSHCGISTRCTERCLCVLPLRTSQVPDVMAPQHDQEKFHDLAYSCLGKSFSMSNQDLYGYSTSSLALGLAWLSWETKKKNVLHLVGLDSL", "length": 156, "molWeight": 17231, "crc64": "939C3E7168FE35CE", "md5": "138D7A94F317974FF5936CD520D28AA8"}}
{"primaryAccession": "Q14BA6", "text": "This is Mesenteric estrogen-dependent adipogenesis protein protein, from Mouse, contains 303 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q14BA6", "organism_name": "Mouse", "protein_name": "Mesenteric estrogen-dependent adipogenesis protein", "length": 303, "firstPublicDate": "2007-02-06", "FUNCTION": "Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATAACEPVARPSLTSISSGELRSLWTCDCELALLPLSQLLRLQPGAFQLRGEQLLVPGPGEPAAARGGFNVFGDGLVRLEGQLYRLSSYIKRYVELTNYCDYKDYRETILSKPMVFFINVQTKKDISKERTYAFLVNTRHPKIRRQIEQGMDMVISSVIGESYRLQFDFQEVVKNFFPPGTIVLNGENLSFTYEFKADALFDFFYWFGLSNSTVKVHGKVLNLTSTNPEKKETIKLFLEKMSEPLIRRSSFSDRKFSVTSRGSIDDVFNCNLSPRSSVTEPLLAEFSFPSLLECEETSSQLI", "length": 303, "molWeight": 34364, "crc64": "E06A5C25AF6B80EC", "md5": "364A69A3CBD6F95E5A492FE439CD7333"}}
{"primaryAccession": "Q17025", "text": "This is Chymotrypsin-2 protein, from African malaria mosquito, contains 258 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q17025", "organism_name": "African malaria mosquito", "protein_name": "Chymotrypsin-2", "length": 258, "firstPublicDate": "1997-11-01", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLRKVFAVVSVLLVVSAAKVTKLVLDDHYVNRVVGGEVAKNGSAPYQVSLQVPGWGHNCGGSLLNNRWVLTAAHCLVGYEPSDLMVLVGTNSLKEGGELLKVDKLLYHSRYNRPQFHNDIGLMRLEQPVQFSELVQSVEYLEKAVPVNATVRLTGWGRTSTNGNVPTLLQSLNVVTLSNEDCKAKMGNPKNVDLGHVCTLTKAGEGACNGDSGGPLVYEGKLVGVVNFGVPCGRGFPDGFARVSYYHEWVRTTMANNS", "length": 258, "molWeight": 27928, "crc64": "8C82E91B5C790EB8", "md5": "542DEFD5753F495C94A4871972F308DF"}}
{"primaryAccession": "Q1MTQ5", "text": "This is Phospholipid-transporting ATPase accessory subunit mug89 protein, from Fission yeast, contains 396 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q1MTQ5", "organism_name": "Fission yeast", "protein_name": "Phospholipid-transporting ATPase accessory subunit mug89", "length": 396, "firstPublicDate": "2007-02-20", "FUNCTION": "Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the lumenal to the cytosolic leaflet of membranes and ensures the maintenance of asymmetric distribution of phospholipids", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the CDC50/LEM3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPEALNENVSDTASNGPVAKTRAPPNTSFRQQRIKSWQPLLTPKIVLPLFFVLGIIFGPLGGGLLYASSIVQELVVDYTDCETLASYDEFSAVPSKKYTASFDQSGTIGFDKESTYWKLEKILDKDLDMDVNYCIIRFTVPSVLKAPIFIYYRLTNFFQNHRRYAKSVDEKQLQGVALTADEVKGGNCFPLEVNEDDKPYYPCGLIANSLFNDTFSSLRLLDDNSVYTFSTKNIAWASDKRRFLKTNYSPDDVAPPPNWVLRYPDGYTESNMPDLSTMENLQVWMRTAGLPTFSKLAMRNDNDDIFPGTYEIKIGLFFPVKSFDGTKSLVLTTRSVLGGKNPFLGIAYIVVSAVCVVLGTVFTLRHFIRPRKLADHRYLNWDSEENNLAPHLSDRP", "length": 396, "molWeight": 44743, "crc64": "EA7C860C50C86026", "md5": "7045700ABF0994583B94794D871EC801"}}
{"primaryAccession": "Q1PFN9", "text": "This is Pumilio homolog 9 protein, from Mouse-ear cress, contains 564 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q1PFN9", "organism_name": "Mouse-ear cress", "protein_name": "Pumilio homolog 9", "length": 564, "firstPublicDate": "2010-11-30", "FUNCTION": "Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGFGGFNGDFNFRGASDHRPLGSDGFLPSLDTNPFLKNHKSVEALDLCKKLHKMGISCDMSIWTKPEEQFRVDPSEFGARTLHGSSGFDQNLTGASQIHDGFRNFSSVRLQNNNFHGVSPSPGEMRLLGRQDSFNLNGFEEMLALKNHRDFLLDQIHEPIKRPPFLRGNDALISSLMFEGNNRVSQTLAAMEASRGFYPEEDSSLLSPFHEKVSGKLGASYLEDTVLIGQGSYGKMSPKSNNDLVSMVEIYGSVNLMAKDQIGCRVLQKLVEEGTFHEAKVILLAIIDHVVELSMDPFGNYIVQKLFDVSDEEQRTLIVSVLTSNPRELIRICLNTYGTRVVQKMIETVKTKQQIALVKSGLKPGFLALVKDLNGNHVIQSCLQTLGPNDNEFVLEAATKYCAEIAIHRHGCCVLQCCISNSVGLQRERLVAEISRNSLHLSQDPFGNYVVQYLIDQQVSAVKLLVQFRMHYAELATQKFSSHVIEKCLRKYPESRAEIVRELLCVPNFEYLLQDPYANYVIQTALSVTKGPVRAKLVAKVYRYGKLHSSPYCKKIFSKTILKK", "length": 564, "molWeight": 63251, "crc64": "879C475D3FC5EE2B", "md5": "02150D409ECBBDD136EF9B8DDC6E848C"}}
{"primaryAccession": "Q20374", "text": "This is Protein PAT1 homolog 1 protein, from Caenorhabditis elegans, contains 833 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q20374", "organism_name": "Caenorhabditis elegans", "protein_name": "Protein PAT1 homolog 1", "length": 833, "firstPublicDate": "2011-02-08", "FUNCTION": "RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs, Acts as a scaffold protein that connects deadenylation and decapping machinery (By similarity), Required for the recruitment of P-body components such as cgh-1 in somatic blastomeres (PubMed:18692039), May play a role in recruiting the decapping enzyme dcap-1 to cytoplasmic puncta in the cell body of the posterior touch receptor neuron, PLM (PubMed:31983639)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the PAT1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEEVKKYGKTLEEIEGGLMFDDFPESLVDSDEDHNIFDDEFDAANDETFGGGLDNIGENAELENYATQTAKLRFDDPVWQKPSSSDHVAPSASEIPIPFPNFGNGDASDSFKSSFEAESPFLKKSIWGNGTDGAYNIWGTNFGISSVPAAPTLDLDFGALLPTPTIQATKEVKSSQIPSMPSSALTLEDCERMQMGNKPDSLVDAFKDLQLGSTPVQPQSAQFSKHPLEARIAAPGTPATASSQALPTLPTAALSLEELELQIMKEAQILKGRQQVPSDMREDNKFSHPPPGFNQNVQPRMDPSLSPGGMHGMPPSMGTSMPHMGPMMPPQNMQLPRLPPLNPQFLPLIPVWFNAIINNIQLPMGVPPPPPFLFQLLNHYRNPQLVHAMIMQSSIPPNIRQNGPQFSHPSGPHSPGNRVQRKHSGMPSTRTIYDLALDSFAGYMSYKEREWLIRIQFIQCKGSGDPQVDDYYYVTWRDKQIANGWTAETKLEEATKEKKEKSSESQKDYLERISRMNYREMQKERARERDKERQRERQERIDRGEDKKLRQTLSDKFATSLGLPSKSSTHNPRHVLDMKAQVESVDNQTKKLSDEERKIAVAKKLRTMLLRLEGALNILMEVDELRRSSLPEKSQFKDLSSDEKDQEVEKRTTVIINELMGDDLSKLMQMSKGRAVITRTLKVVEPRDQARIILALMTAGGLVSKKMYGEIVLDILPVVYQKVSNLHPDQFKYLVGALNLDTLKRQLLDSNMFIRDMMMTLFFVSVKNNQQLVEWAKATKFSSLKMPSSAPLSIWRKALSVISDSEIKEFADDIKYSGIVDCHDVAQLIEQSL", "length": 833, "molWeight": 93672, "crc64": "5047A926A94E2EE5", "md5": "B94433911CCDA570DAC624FB74C91DDE"}}
{"primaryAccession": "Q27289", "text": "This is Chymotrypsin-1 protein, from African malaria mosquito, contains 259 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q27289", "organism_name": "African malaria mosquito", "protein_name": "Chymotrypsin-1", "length": 259, "firstPublicDate": "1997-11-01", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLRKVFAVVSVLLVVSAAKVTKLVLDDNYVNRVVGGEVAKNGSAPYQVSLQVPGWGHNCGGSLLNDRWVLTAAHCLVGHAPGDLMVLVGTNSLKEGGELLKVDKLLYHSRYNLPRFHNDIGLVRLEQPVRFSELVQSVEYSEKAVPANATVRLTGWGHTSANGPSPTLLQSLNVVTLSNEDCNKKGGDPGYTDVGHLCTLTKTGEGACNGDSGGPLVYEGKLVGVVNFGVPCALGYPDGFARVSYYHDWVRTTMANNSK", "length": 259, "molWeight": 27722, "crc64": "3EF7D6F19EAAED23", "md5": "BC979C06B87F7E49C77FA5F46842F9A3"}}
{"primaryAccession": "Q28388", "text": "This is Uterocalin protein, from Horse, contains 180 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q28388", "organism_name": "Horse", "protein_name": "Uterocalin", "length": 180, "firstPublicDate": "2006-09-19", "FUNCTION": "Binds fatty acids and retinol, Is specialized for the preattachment embryo, May be important to maintain the pregnancy and may transport small hydrophobic ligands from mother to the developing embryo", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the calycin superfamily, Lipocalin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNLLLLAMGLILPRRPHALHMGPGDPNFDEKLVKGKWFSVALASNEPKFIAKDTDMKFFIHKIQVTPESLQFHFHRKVRGMCVPTMMTAHKTKKKFQYTVNHSGHKTIFLEKVDPKHFVIFCAHSMKHGKETVVVTLFSRTPTVSPDVMWMFKKYCKTHGIHTSNIVDLTQTDRCLHARH", "length": 180, "molWeight": 20805, "crc64": "892BB394BEF93417", "md5": "40B183EDE32F42D5378E49AEEDA07D3D"}}
{"primaryAccession": "Q2TBR2", "text": "This is Large ribosomal subunit protein bL20m protein, from Bovine, contains 149 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q2TBR2", "organism_name": "Bovine", "protein_name": "Large ribosomal subunit protein bL20m", "length": 149, "firstPublicDate": "2006-09-05", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL20 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVFLSAPLWLRNRITDRYWRVQEVLKHARHFRGRKNRCYRLAVRAVTRAFVRCTRARSLKKRHLRTLWINRITAASQEHGLKYPAFILNLIKCQVELNRKVLADLAIYEPKTFKSLAALSKRRREEGFVAALGDGKEPEGIFSRVAQHH", "length": 149, "molWeight": 17535, "crc64": "C33BCB5E52F4D6A9", "md5": "5EB22CF222B5AAE12A67FA9ED1467F1B"}}
{"primaryAccession": "Q2WFL8", "text": "This is Protein shisa-2 protein, from African clawed frog, contains 288 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q2WFL8", "organism_name": "African clawed frog", "protein_name": "Protein shisa-2", "length": 288, "firstPublicDate": "2008-04-29", "FUNCTION": "Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both fgf and wnt signaling, Inhibits both wnt and fgf signaling through the regulation of protein maturation and cell surface transportation of their receptors within the endoplasmic reticulum", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the shisa family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MWLEGSPLAVLAAVSFLLSVLAAAQGSGEYCHGWLDAQAVWRDGFQCPERFDGDDSTICCGKCELRYCCSSAEARLDQGVCNNDRQQGAPDHNRPDKDSPDSTAVPIYVPFLIVGSVFVAFIIVGSLVAICCCRCLRPKQEPQQSRAPGSNRLMETIPMISSASTSRGSSSRQSSTAASSSSSANSGARPPPTRSQTNCCLPEGAMNNVYVNMPTNFSVLNCQQATQLVQHQGQYLHPQFVGYAVPHDSVPMTPVPQFIDGLQGGYRQMQSPYPHSNPEQMMYPAVTV", "length": 288, "molWeight": 31119, "crc64": "1689B345D7D30780", "md5": "31FE2936E31828757C58E2BB90E59E86"}}
{"primaryAccession": "Q2YDF6", "text": "This is Small ribosomal subunit protein mS35 protein, from Bovine, contains 325 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q2YDF6", "organism_name": "Bovine", "protein_name": "Small ribosomal subunit protein mS35", "length": 325, "firstPublicDate": "2006-02-07", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mS35 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAPSLPAWLALQTRARTLRAFSTAVSPVTGAQRLSPPTTERTSKHERAPRRKALPPRTEKMSVDQDWPSVYPVAAPFKPSAVPLPVRMGYPVKRGVPMAKEGNLELLKIPNFLHLTPVAIKKHCEALKDFCTEWPAALDSDEKCEKHFPIEIDTADYISSGPSIRNPKARVVTLRVKLSSLNLDDHAKKKLIKLVGDRYCKSTDVLTIKTDRCPLKRQNYDYAMYLLTVLYHESWKTEEWEKKKTEADMEEYVWKDSASEKNILETLFQIKAAEKNTELSKEELLSTKEVEDYKNSVVSLKNEGDNENTISQYKESVKRLLHLM", "length": 325, "molWeight": 37070, "crc64": "0C202F0C4F553E46", "md5": "999F7EE4A6600197A48B4AAE681747AA"}}
{"primaryAccession": "Q32MW3", "text": "This is Acyl-coenzyme A thioesterase 10, mitochondrial protein, from Mouse, contains 439 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q32MW3", "organism_name": "Mouse", "protein_name": "Acyl-coenzyme A thioesterase 10, mitochondrial", "length": 439, "firstPublicDate": "2007-10-02", "FUNCTION": "Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels, Active on long chain acyl-CoAs", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the acyl coenzyme A hydrolase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKRAAMRLWTLNKGLLTHGRGLSQGSQYKISEPLHIHQVQVKLREIVGISTVWRDHVQAMEERKLLHSFLPKSQKVLPPRKIRDSYIEVLLPLGTDPELRDKYVTVQNTVRFGRILEDLDSLGVLVCYMHNHNHSTNMSLLSIVTVLVDKIDMCKHSLSPEQDIKFTGHVSWVGNTTMEVKMKMFQLHDDETYWPVLDATFVMVAQDSENKRPAFVNPLIPENKEEEELFTQGELNKSRRIAFSTSSLLKVAPSSEERNIIHELFLSTLDPKTISFQSRILPPKAVWMEDTKLKSLDICHPQERNVFNRIFGGFLMRKAYELAWATACSFGGSRPYVVTVDDIMFQKPVEVGSLLFLSSQVCFTQGNYIQVRVHSEVFSLDSREHMTTNVFHFTFMSEKEVPLIFPKTYGESMLYLDGQRHFKSMSTPVTLKKDYPVEP", "length": 439, "molWeight": 50552, "crc64": "A1BE1226F663250C", "md5": "FBDAC2EC049489DDD29CCB2240626080"}}
{"primaryAccession": "Q32NK7", "text": "This is Protein odd-skipped-related 2-A protein, from African clawed frog, contains 271 amino acids, has 3 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [172, 194], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [200, 222], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [228, 250], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "Q32NK7", "organism_name": "African clawed frog", "protein_name": "Protein odd-skipped-related 2-A", "length": 271, "firstPublicDate": "2010-01-19", "FUNCTION": "Transcriptional repressor, Required for pronephric kidney development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the Odd C2H2-type zinc-finger protein family", "domain_description": {"C2H2-type Zinc finger": 3}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGSKALPAPVPLHPSLQLTNYSFLQAVNTFPAAVDHLQGLYGLSAVQTMHMNHWTLGYPNLHGLTRSTITEMAAAQGLMDARFSFPALPFATHLFHPKQGTIAHVIPALHKDRPRFDFANLAIAATQEDPPKIGDLSKLSPGLGSPISEISKLSPDRKPSRGRLPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQTSSPTVVSSAEKFSGEIAI", "length": 271, "molWeight": 30300, "crc64": "00E0287C9E35D3C4", "md5": "3EB5AEBB0F7DF5AC7F23459EB50582C4"}}
{"primaryAccession": "Q39002", "text": "This is ADP,ATP carrier protein 1, chloroplastic protein, from Mouse-ear cress, contains 624 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q39002", "organism_name": "Mouse-ear cress", "protein_name": "ADP,ATP carrier protein 1, chloroplastic", "length": 624, "firstPublicDate": "2000-05-30", "FUNCTION": "May function as an ATP importer", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the ADP/ATP translocase tlc (TC 2,A,12,2) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEAVIQTRGLLSLPTKPIGVRSQLQPSHGLKQRLFAAKPRNLHGLSLSFNGHKKFQTFEPTLHGISISHKERSTEFICKAEAAAAGDGAVFGEGDSAAVVASPKIFGVEVATLKKIIPLGLMFFCILFNYTILRDTKDVLVVTAKGSSAEIIPFLKTWVNLPMAIGFMLLYTKLSNVLSKKALFYTVIVPFIIYFGAFGFVMYPLSNYIHPEALADKLLTTLGPRFMGPIAILRIWSFCLFYVMAELWGSVVVSVLFWGFANQITTVDEAKKFYPLFGLGANVALIFSGRTVKYFSNLRKNLGPGVDGWAVSLKAMMSIVVGMGLAICLLYWWVNRYVPLPTRSKNKKEKPKMGTMESLKFLVSSPYIRDLATLVVAYGISINLVEVTWKSKLKAQFPSPNEYSAFMGDFSTCTGVATFTMMLLSQYVFNKYGWGVAAKITPTVLLLTGVAFFSLILFGGPFAPLVAKLGMTPLLAAVYVGALQNIFSKSAKYSLFDPCKEMAYIPLDEDTKVKGKAAIDVVCNPLGKSGGALIQQFMILSFGSLANSTPYLGMILLVIVTAWLAAAKSLEGQFNSLRSEEELEKEMERASSVKIPVVSQDESGNGSLGESPSSSPEKSAPTNL", "length": 624, "molWeight": 68134, "crc64": "530302A89AD08745", "md5": "672A45199A5758F5D69CB5FB94311999"}}
{"primaryAccession": "Q3SYS1", "text": "This is Large ribosomal subunit protein uL13m protein, from Bovine, contains 178 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3SYS1", "organism_name": "Bovine", "protein_name": "Large ribosomal subunit protein uL13m", "length": 178, "firstPublicDate": "2006-04-04", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASLSRAPQQWATFARVWYLLDGKMQPPGKLAALASVRLQGLHKPVYHQLSDCGDHVVIMNTRHIAFSGNKWEQKVYSSHTGYPGGFKQVTAAQLHRKDPVAIVKLAIYGMLPKNLHRRTLMQRLHLFPDEDIPEDILKNLTEELPQPRKVPRRLDEYTQEEIEAFPRVWSPPEDYRL", "length": 178, "molWeight": 20575, "crc64": "BFE755D10DACC589", "md5": "0ABB5AE88E6B38117D3D90ECC9F41570"}}
{"primaryAccession": "Q3T0L3", "text": "This is Large ribosomal subunit protein bL17m protein, from Bovine, contains 172 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3T0L3", "organism_name": "Bovine", "protein_name": "Large ribosomal subunit protein bL17m", "length": 172, "firstPublicDate": "2006-05-30", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL17 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRLSFAAAISHGRVYRRLGLGPESRIHLLQNLLTGLVRHERIEASWARVDELRGYAEKLIDYGKLGDTNERAMRMADFWLTEKDLIPKLFQVLAPRYQGQNGGYTRMLQIPNRNQQDRAKMAVIEYKGNCLPPLPLPRRDSNLTLLNQLLRGLRQDQEASTRSSHPAQTPEV", "length": 172, "molWeight": 19746, "crc64": "3BF66CD4421BB948", "md5": "9488A57B1248FC7C8A193B45C50D96DE"}}
{"primaryAccession": "Q3TZW7", "text": "This is Protein BEX6 protein, from Mouse, contains 114 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3TZW7", "organism_name": "Mouse", "protein_name": "Protein BEX6", "length": 114, "firstPublicDate": "2006-04-04", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the BEX family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMSKVKQVIQDLTVEKDKGGEASRHSEEESHLLEEVETKNPGGYVKRKVRRLVCNFRWPTPNRHVDHSEGREDAGRFVGQETEAKRKSQEQWMRFSKWFLTPESDSHYNLGLIP", "length": 114, "molWeight": 13353, "crc64": "206939778CBCB7DD", "md5": "B823862BF06534786FD3CE033613AFA7"}}
{"primaryAccession": "Q3YEE8", "text": "This is Conotoxin TeAr154 protein, from Cloth-of-gold cone, contains 61 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3YEE8", "organism_name": "Cloth-of-gold cone", "protein_name": "Conotoxin TeAr154", "length": 61, "firstPublicDate": "2007-01-23", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the conotoxin T superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MHCLPVFVILLLLTASGLSVDARPKTEDDVPLSSFRDNTKSTLQRLLKRVNCCPIDESCCS", "length": 61, "molWeight": 6751, "crc64": "44E02F68DC0908D5", "md5": "BA6520488EDA19A143DE88FCCC66577E"}}
{"primaryAccession": "Q3YEE9", "text": "This is Conotoxin TeAr151 protein, from Cloth-of-gold cone, contains 62 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3YEE9", "organism_name": "Cloth-of-gold cone", "protein_name": "Conotoxin TeAr151", "length": 62, "firstPublicDate": "2007-01-23", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the conotoxin T superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRCLPVFVVLLLLIASAPSVDAQPKTKDDVPLAPLHDNIQNTLQTLRKKVCCRPMQDCCSGK", "length": 62, "molWeight": 6834, "crc64": "37930ADB8105E1ED", "md5": "EA6873EEF20C3CAF283491AA827B7818"}}
{"primaryAccession": "Q3YEH7", "text": "This is Conotoxin 3 protein, from Cloth-of-gold cone, contains 61 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3YEH7", "organism_name": "Cloth-of-gold cone", "protein_name": "Conotoxin 3", "length": 61, "firstPublicDate": "2007-01-23", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the conotoxin T superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRCLPVFVILLLLIASVPSDAVQLKTKDDMPLPSFNGNARRTPRMLSNKRICCYPNVWCCD", "length": 61, "molWeight": 6925, "crc64": "618F8FF5690EBC12", "md5": "E1F43D970DB680006A14D477B70D16A5"}}
{"primaryAccession": "Q3ZCI1", "text": "This is Transmembrane protein 14C protein, from Bovine, contains 114 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3ZCI1", "organism_name": "Bovine", "protein_name": "Transmembrane protein 14C", "length": 114, "firstPublicDate": "2008-04-08", "FUNCTION": "Required for normal heme biosynthesis", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the TMEM14 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPKDSGPLVPLHWLGFGYAALVASGGIIGYAKAGSVPSLAAGLLFGGLAGLGSYQLSQDPKNIWLFLVTSGTLAGIMGMRFYNSRKFMPAGLIAGASLLMVVKLGISALSKPHQ", "length": 114, "molWeight": 11735, "crc64": "5E71B8329BC5E360", "md5": "D44301F715B230E92EF45F672F022B7B"}}
{"primaryAccession": "Q42191", "text": "This is Mitochondrial inner membrane protein OXA1 protein, from Mouse-ear cress, contains 429 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q42191", "organism_name": "Mouse-ear cress", "protein_name": "Mitochondrial inner membrane protein OXA1", "length": 429, "firstPublicDate": "2003-11-14", "FUNCTION": "Required for the insertion of integral membrane proteins into the mitochondrial inner membrane, Essential for activity and assembly of cytochrome c oxidase", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the OXA1/ALB3/YidC (TC 2,A,9,2) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFRQTLSIRSRLFARRNQPVYHIIPRESDHERDSFCQETSQRSYHSFLHQRSVNNSDFSKVSGGSLHLPLAPTSGFAFYRYMSSAPGVGSEKIGVMSDIAEVITDSTLQDVPAQAAAAVSEVTLAAADSFFPIAALQQCIDMVHTFTGFEWWASIVVATILIRSSTVPLLIKQMKDTTKLALMRPRLESIREEMQNKGMDSVTMAEGQKKMKNLFKEYGVTPFTPMKGMFIQGPLFICFFLAIRNMAEKVPSFQTGGALWFTDLTTPDSLYILPVITGLTFLITVECNAQEGMEGNPMAGTVKTVCRVFALLTVPMTMSFPQAIFCYWITSNLFSLMYGLVIKRPQVKKMLRIPDLPPPPPGQQPSFDLFSALKKMKAMTQDHTQNQIEPPSPVNPRLSSTSLSPVSKRLKALESQVKGRKKNSSKKK", "length": 429, "molWeight": 47860, "crc64": "EDFF434DE689A007", "md5": "B5FC5F40CC5C5DA13D4CFB6C52BAEC3F"}}
{"primaryAccession": "Q4TTV7", "text": "This is Lectizyme protein, from Savannah tsetse fly, contains 274 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q4TTV7", "organism_name": "Savannah tsetse fly", "protein_name": "Lectizyme", "length": 274, "firstPublicDate": "2007-06-26", "FUNCTION": "Protein with lectin and protease activity involved in the establishment of trypanosome infections in tsetse flies, Binds D-glucosamine and agglutinates bloodstream-form trypanosomes and rabbit red blood cells, Capable of inducing transformation of bloodstream-form trypanosomes into procyclic (midgut) forms in vitro", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFFAVFALCVASVSAANLDAIAKPGFPAGRIINGHEAEKGEAPFIVSLKAGKGHFCGGSIIAENWVLTAGHCLIFDEFEIVAGLHSRNDESDVQIRKVTGKHQQIVHEKYGGGVGPNDIGLIYVDKPFNLNALTRDGTAAVAKVNLPTGKYESTGEGKLYGWGLDNSGFSPNILNTLDVNIIGYEECKNALNSDAPLDPVNICSYTAGAIDGACNGDSGGPMVRITPDGTELVGIVSWGYQPCASTTMPSVYTWTSAFDKWIEDSIENYAQLL", "length": 274, "molWeight": 29151, "crc64": "ADFF48DE50710349", "md5": "8986336EAEB56F0CFDE090A3176D6E85"}}
{"primaryAccession": "Q59L72", "text": "This is GPI-anchored protein 52 protein, from Yeast, contains 384 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q59L72", "organism_name": "Yeast", "protein_name": "GPI-anchored protein 52", "length": 384, "firstPublicDate": "2014-07-09", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the PGA52 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLFSSLLVSTLVSVATAANQEVEAIQFSNLGFSGTYNQVEKLSNIYKDSCSCEVNKTPVSFSGTNAPLNEEVSVHFRGPLVLNKFASYVSDGFKYGDDSSGDWKRLSYYEGSSGTSENVTFLTSAGKNSSCLGIGLTYAGTDGISKADSSTVLAKNTLINSNDEFVIFSNISCGKSGYNNDCGVYRSDIPAYHGFYGTTKMFLFEFQMPNETHTSTDISNYNMPAIWLLNAHIPRTAQYSMNVNCSCWRSGCGEFDIFEVMNSTEYLHMYSTIHDYQGSDDIQTGMAAPAYIERDLTGTMSGGVAFDSSGNAVVWVSNSTSFDSTIQASSVNSWVKQAGADVATTLATVTGQSATTTSKKSGGVSYQPSFITNLLMTVLTLWVI", "length": 384, "molWeight": 41476, "crc64": "9E6E5973A887E994", "md5": "05D25BA706E1F90DB9525386EA00F2EA"}}
{"primaryAccession": "Q5BD29", "text": "This is Probable beta-glucosidase btgE protein, from Aspergillus nidulans, contains 555 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5BD29", "organism_name": "Aspergillus nidulans", "protein_name": "Probable beta-glucosidase btgE", "length": 555, "firstPublicDate": "2010-06-15", "FUNCTION": "Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass, Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 17 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGAILATAAAFAGTAVADMHMRRHAHEGLHHRALHASSAVPEEECGCTTEVITYWGEPTTIPLSVPTSTVTSETTETVHSTSYSTVTVTATSSAAPVETPSETPSPTPEVTLPTAGVTSYSETGTYTIPATTITVTDTTTVCGATTTELPSGTHTYGGVTTIVETATTITCPYATVKPTGSTVTSVIETTTYVCPSAGTYTIAPTTTFVPTSTVVVYPTPETVTPGTYTNPGTTITVTRTEDVYVCPYTNGNVPTSVPALPTTSAASTTTAVPSSSTTTSSATSVPTGASGNKMGMTFTPYNNDGSCMAKNDVLEQVGLIKGKGFSHVRVYGTDCHTLEYVGAACSTHGLKMILGVNVEGSTGFDGARSQFKDITNWGQWDLVSLIVVGNEVVTSNIASAAQLASFVSEGASAFSAAGYTGQVTTAEPIDVWLSNGATLCPVVDILGANLHPFFNPEFTAAEAGTLVSNQIKDLKQVCTGKDVINLETGWPNAGSANGKAIPGQSQQTTAIKSLVEKVGDVSVFFSYADDGWKSKFATSDKYNVEQHWGCIDQF", "length": 555, "molWeight": 57672, "crc64": "B8F0DF0153079DCA", "md5": "D0B0FFD9BA1B6EF8DBAD33EAAE57FF30"}}
{"primaryAccession": "Q5HZV9", "text": "This is Protein phosphatase 1 regulatory subunit 7 protein, from Rat, contains 360 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5HZV9", "organism_name": "Rat", "protein_name": "Protein phosphatase 1 regulatory subunit 7", "length": 360, "firstPublicDate": "2006-06-13", "FUNCTION": "Regulatory subunit of protein phosphatase 1", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SDS22 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHGGGIVADLSQQSLKDGVERGAEDPEEEHELAVDMETISLDRDAEDVDLNHYRIGKIEGFEVLKKVKSLCLRQNLIKCIENLDELQSLRELDLYDNQIKKIENLEALTELEVLDISFNLLRNIEGIDKLTQLKKLFLVNNKINKIENISTLQQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALSNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF", "length": 360, "molWeight": 41297, "crc64": "1CDA9FB2ACC02400", "md5": "11610C62605C29E19CBB17BE9556D895"}}
{"primaryAccession": "Q5U3Z0", "text": "This is Cilia- and flagella-associated protein 298 protein, from Rat, contains 290 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5U3Z0", "organism_name": "Rat", "protein_name": "Cilia- and flagella-associated protein 298", "length": 290, "firstPublicDate": "2014-01-22", "FUNCTION": "Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly, Seems to be important for initiation rather than maintenance of cilium motility, Required for correct positioning of cilia at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway, May suppress canonical Wnt signaling activity", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the CFAP298 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVVLHVKRGDESQFLLQAPGSTELEELTAQVTRVYNGRLKVHRLCTEIEELAEHGVFLPPNMQGLTDEQIEELKLKDEWGEKCVPSGGSVFTKDDIGRRNGHAPNEKMKQVLKKTVEEAKAMVSKKQVEAGVFVTMEMVKDALDQLRGAVMIVYPMGLPPYDPIRMEFENKEDLSGTQAALEVIQESEAQLWWAAKELRRTKKLSDYVGKNEKTKIIVKIQQRGQGAPAREPLISSEEHKQLMLFYHRRQEELKKLEENDDDSCLNSPWADNTALKRHFHGVKDIKWRPR", "length": 290, "molWeight": 33243, "crc64": "DAA9B88C40867687", "md5": "02E4BE1684013F87328C906D8BCF8582"}}
{"primaryAccession": "Q5ZIH3", "text": "This is Zinc transporter 6 protein, from Chicken, contains 460 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q5ZIH3", "organism_name": "Chicken", "protein_name": "Zinc transporter 6", "length": 460, "firstPublicDate": "2007-12-04", "FUNCTION": "Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway (Probable), As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis (By similarity)", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the cation diffusion facilitator (CDF) transporter (TC 2,A,4) family, SLC30A subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGTIHLFRKSQRSLVGKLTHEFRLVAADRRSWKILLFGAINLICIGFLLMWCSSTNSIALTAYTYLTIFDLFSLITCLISYWVMVKKPSPVYSFGFERFEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALFFNLFTMLSVRNKPFAYVSEAASTSWLQEHVADLSRSICGIIPGLSSIFLPRMNPFVLIDIAGALALCITYMLIEINNYYAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVFGQLDKLLREVSTLDGVLEVRNEHFWTLGFGTLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPTLSSVPIANNMLNLSDHHVITMPSLKAADNLNPVTSTPAKPSSPPPEFSFNTPGKNVNPVILLNTQTRPYGLGLNHGSTPYSSVLNQGFGIPGMGATQGFRTGFTNVPSRYGTNTRGQSRP", "length": 460, "molWeight": 50936, "crc64": "6D9EB207DC180E82", "md5": "2F9A9AC24ACE3DDC923C43C0528B7141"}}
{"primaryAccession": "Q65YR7", "text": "This is Cystatin-A2 protein, from Social amoeba, contains 95 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q65YR7", "organism_name": "Social amoeba", "protein_name": "Cystatin-A2", "length": 95, "firstPublicDate": "2008-04-08", "FUNCTION": "Intracellular thiol proteinase inhibitor, Inhibits cathepsin B, but not papain", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the cystatin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTKVGGLGATHQADKTVEDIVNAVKPSIQSKLGTNISNLKVISYKTQLVNGTNYFVKVRTENGYAHLRIYKPFSGAASLVSVQDGKAKDDEITYF", "length": 95, "molWeight": 10351, "crc64": "8255C5A257B3CDBB", "md5": "13BA332D53B216DB6190EC708397F9C8"}}
{"primaryAccession": "Q65YR8", "text": "This is Cystatin-A1 protein, from Social amoeba, contains 94 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q65YR8", "organism_name": "Social amoeba", "protein_name": "Cystatin-A1", "length": 94, "firstPublicDate": "2008-04-08", "FUNCTION": "Intracellular thiol proteinase inhibitor, Inhibits papain, but not cathepsin B", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the cystatin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTLGGLKPEVHAANDEIRQVVAKVADELKSKLNTTEVEPVSYKTQLVAGTNYFIKVKTPAGFAHARVYKDLQQNHSVHSVKADGITEESEIVYF", "length": 94, "molWeight": 10401, "crc64": "8D03C836DD6B5E4B", "md5": "3C5540D6A49D7DFB0E9F78E292459776"}}
{"primaryAccession": "Q66S21", "text": "This is Natterin-2 protein, from Copper Joe toadfish, contains 376 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q66S21", "organism_name": "Copper Joe toadfish", "protein_name": "Natterin-2", "length": 376, "firstPublicDate": "2007-05-01", "FUNCTION": "Shows nociceptive, edema-inducing and kininogenase activity with release of kallidin from low molecular weight kininogen, The cleavage occurs at Met-Lys bonds", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the natterin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNLSVLLVTLLLLSWTSAEKDLKVRVARSTNDETNLHWVKCGGSVPDGAVSIRNTYVSPARTEYVCKCFCQAGYYSTKDSKCHYPYGTKEMATSTNCYILVNRDNFELLEWKDGYAGSVPDNAVSTCKTNKIYVGKGAYGLGKIEPANHCLYYVWDGAETWTKTYQALTMNKDVIEQAMKDVKYQTEGVTVIKGKPEVMRRSTVNNQHCKEVTKTVTLTKDISTDERWDVTNSVTFGVTTTVTAGIPDVSSASLEISMQATMDFAHGASKTETQSYMVTVSVPVPPKQSCTVSMVAQVNKADIPFTATLIRTYRGGKKTQTTTKGVYRTIQVAETHADVEQCTIIGDAKDCPNASSTITTLRPKLKSKKPAKPAGK", "length": 376, "molWeight": 41327, "crc64": "9D64F34CB55F51C2", "md5": "1007C7A76FA658E78AC4F0CA067179B2"}}
{"primaryAccession": "Q66S25", "text": "This is Natterin-1 protein, from Copper Joe toadfish, contains 355 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q66S25", "organism_name": "Copper Joe toadfish", "protein_name": "Natterin-1", "length": 355, "firstPublicDate": "2007-05-01", "FUNCTION": "Shows nociceptive, edema-inducing and kininogenase activity with release of kallidin from low molecular weight kininogen, The cleavage occurs at Met-Lys bonds", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the natterin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIPSVLLVTLLLLSWTSAEKDLKVRVARSTNDETNLHWVKCGGSVPDGAVSIQNTYVSPARTEYVCKSNCEAGYYSTKDSKCHYPFGRVEQTTSVCEILVNRDNFELLEWKEGYAGSLPANAVSTCKTNRIYVGKGAYGLGKIEPAHHCLYYGWNGAETWTKTYQALTVNKDVIEQTMKDVKYQTEGVTVIQGKPEVMRKSTVNNKQCKEVTKTVTLSKDISTEERWDVTNSVTFGVTTTVTAGIPDVASASLAVSMEARRDFAHGASKTESQSYMVTVSVPVPPKQSCTVSMVAQVNKADVPFTATLIRTYRGGKKTQTTTKGVYRTTQVAETHADVEQCTIIGDEKDCPKASK", "length": 355, "molWeight": 38994, "crc64": "CF4AFB2F0F328028", "md5": "550D29AB89975AA0DC59D02D5A1FBE6E"}}
{"primaryAccession": "Q681Y3", "text": "This is Putative transferase At1g60990, chloroplastic protein, from Mouse-ear cress, contains 432 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q681Y3", "organism_name": "Mouse-ear cress", "protein_name": "Putative transferase At1g60990, chloroplastic", "length": 432, "firstPublicDate": "2015-06-24", "FUNCTION": "Folate-dependent protein involved in Fe/S cluster biogenesis, Functionally complements an E,coli mutant defective in ygfZ", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the GcvT family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNLLQSCKDMAMMMRIDSVSHITNTALLPCLYNGTVLRRRSLSLRKCGFRERKFQLRCVSASSDSLQFDFSPPPIDHDFLDTISVSGGKVSEDGVVESFDNDDEALDAFDNGVVVVDLSHFGRIRVSGDDRAHFLHNQTTANFESLYEGQGCDTVFVTPTARTIDIAHAWIMKNAILLTVSPTTCQSIIEMLNKYIFFADKVEIKDITKQTCLFALAGPKSNQIMSKLNLGDLIGQPYGRHQHYSFDGMPITVGVGSLISDEGFTMLMSPGGAVSVWKTLLAEGAIPMGSVAWEKLRITQGRPAPERELSKEFNVLEAGLWNSISLNKGCYKGQETIARLMTYDGIKQRLCGLNLSAPSEPGSTITVDGKKVGKLTSYTGGKNGSGHFGLGYIKKQAASIGNTVTVGEDISGIVSEVPYLARQHPPSANSSS", "length": 432, "molWeight": 47009, "crc64": "6177B2EFCFFEC6F4", "md5": "6CF2F5651BFD7FC0F114C2828DE09B52"}}
{"primaryAccession": "Q6AX31", "text": "This is Nucleoporin NDC1 protein, from African clawed frog, contains 660 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6AX31", "organism_name": "African clawed frog", "protein_name": "Nucleoporin NDC1", "length": 660, "firstPublicDate": "2006-05-16", "FUNCTION": "Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope, Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the NDC1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTMLGERLVLRWRVAASFAWSVILMPVCCALFIVLSRIQILHPIQWLTDSISDLTSSYTIFCLLLICAILGLQCTFLMEYYTVVPSIPCSRLALIGNLLLPHRILHSLAHVAMGVLASWCYAVLSKGKYQLLVVSCTLQSEDEADKPSHCLNESHLFQLLCGAFFGYSYSLQYFVHNMNYLSFPSIQQYKYLQFRRFLPLIIKQSVFQSLYFIRSYAILYFCLGNIPRTWIQTALNLHMDRQQPSLDTLRGFLNLSLFYQIWLSGTFLLATWYMVWILFRIYTTEARIFPVQTSFAEEAEKCLPFILNSNTLPLVKYLAMQDLVLLSQYSPSRRQEVFSLSQPGGHPHNWTSISKECLNLMSSLTSRLIAHQEAAANNGRMRVPSSPKQIRKSSSSSGTSLIEDSAEQTQNLSTIPRIGIPSLLKTASLKSSLDIGSPFATPGVKQMSESLDPNTPCHGSVQSPQVTRRGAKLWTSDSDVQKNGSEVSPVMHRPVCNGAKQGILHTWFQHKLVQIKNVLSKRGLIMYLFSKHPEASSQDVFADAQIHIWALEALSHLVAASFSEDRMGVVQTSLSSVLAILLTLQEAVEKHFKLPHASSKPARNPGSLLDSSCKTLRFSLRAALKTAIYRITTTFGEHLHAVPVSSEHKKKLQQFLDFKE", "length": 660, "molWeight": 74338, "crc64": "416AAF43AFBAD952", "md5": "FAB560B7A90D3287B6BD95837DB009E0"}}
{"primaryAccession": "Q6B4T4", "text": "This is U1-sicaritoxin-Li1b protein, from Brown spider, contains 105 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6B4T4", "organism_name": "Brown spider", "protein_name": "U1-sicaritoxin-Li1b", "length": 105, "firstPublicDate": "2006-11-28", "FUNCTION": "Toxin active against insects (S,frugiperda larvae), May act on sodium (Nav) or calcium (Cav) channels", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 28 (Litx) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLLFEGLLVLVLIAFVVAEFESDAEKWEALITQERACKGEGVKGCYYEADDWCCKKTPCKCPAWSHERECRCTQPCNPSCRGKRALMVDPETHRMLSLHRLSEE", "length": 105, "molWeight": 12054, "crc64": "0FB8D28E1CC30174", "md5": "47A5B097484D26AE44F63CE50FB44F56"}}
{"primaryAccession": "Q6K8X6", "text": "This is Two-component response regulator ORR23 protein, from Rice, contains 688 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6K8X6", "organism_name": "Rice", "protein_name": "Two-component response regulator ORR23", "length": 688, "firstPublicDate": "2015-09-16", "FUNCTION": "Transcriptional activator that binds specific DNA sequence, Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system, Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes, May directly activate some type-A response regulators in response to cytokinins", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the ARR family, Type-B subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRAAEERKGVVPAARRRDQFPVGMRVLAVDDDPVCLKVLETLLLRCQYHVTTTNQAAIALKMLRENRDMFDLVISDVHMPDMDGFKLLELVGLEMDLPVIMLSVNGETKTVLKGITHGACDYLLKPVRIEELRNIWQHVIRRKFSTRDRANLDFYEECNKPPNADSDHVHGHVTCGSPDQSGRPSKKRKEYCSEEEDEGEVNTQDIDDPSAPKKPRVVWSVELHRKFVAAVNQLGIDKAVPKRILELMNVEKLTRENVASHLQKYRLYLKRLSAVASQQVSIVAALGGRDPFLHMGGFEGLQGYQAFTSSAALSSFTPHGLLNSPRNNPAALGTQGVPASKSIQTMSGSHTLSHSINDANKYHLSLPGNQKGNLGQGLATSLGQTQMQQKWIHEETDDLSTILSGNGLSNGMSGTLQSVTSSPLLPQELAECTQAKIVSQPSIRTSSVSSEHIEGAVGVSSGLLESRVSQQSTIPLSGFSANGLLIHGSFNNTCANKLGGTSSSCAPARSSNDLMVARDTKGGASSFGGAMLLPPDTEQKYLNFGGGNGLKQKFDDRTADSLFDLKFVWSSVPSSQLASNIGAHHAMSQRWNNSSSNSSNIGARMIGQATSSGSTVIPQMKTDFLVSGDMAMPKNASDLSIPKLQSELSSSSCSFDGLLNSIVKVEKDDVTFSDDLGCGDFYSLGACI", "length": 688, "molWeight": 74384, "crc64": "47A54C30CD76CB37", "md5": "2893460F0ADBE2543E9C99578C37C938"}}
{"primaryAccession": "Q6S4P4", "text": "This is Transcription factor RF2b protein, from Rice, contains 329 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6S4P4", "organism_name": "Rice", "protein_name": "Transcription factor RF2b", "length": 329, "firstPublicDate": "2005-07-05", "FUNCTION": "Transcription factor probably involved in vascular development and shoot tissue organization, Binds to the DNA sequence 5'-CCGAGTGTGCCCCTGG-3' present in the promoter region Box II of the phloem-specific rice tungro bacilliform virus (RTBV) promoter, May regulate tissue-specific expression of the RTBV promoter and virus replication", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bZIP family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQEPKHTDPAAMRGAHHRRARSEVAFRLPDDLDLGGGGAGAFDEIGSEDDLFSTFMDIEKISSGPAAAGGSDRDRAAETSSPPRPKHRHSSSVDGSGFFAAARKDAAASLAEVMEAKKAMTPEQLSELAAIDPKRAKRILANRQSAARSKERKARYITELERKVQTLQTEATTLSAQLTLFQRDTTGLSAENAELKIRLQAMEQQAQLRDALNDALKQELERLKLATGEMTNSNETYSMGLQHVPYNTPFFPLAQHNAARQNGGTQLPPQFQPPRPNVPNHMLSHPNGLQDIMQQDPLGRLQGLDISKGPLVVKSESSSISASESSSTF", "length": 329, "molWeight": 35806, "crc64": "20A6568D017816BC", "md5": "24C53F9F1B7681DECCA7C122BE53AAF4"}}
{"primaryAccession": "Q6T6C1", "text": "This is Theromyzin protein, from Duck leech, contains 107 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6T6C1", "organism_name": "Duck leech", "protein_name": "Theromyzin", "length": 107, "firstPublicDate": "2008-07-01", "FUNCTION": "Has bacteriostatic activity against M,luteus, No activity toward E,coli and F,oxysporum", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MHAKIILALFLGMTAFLAVQADHHHDHGHDDHEHEELTLEKIKEKIKDYADKTPVDQLTERVQAGRDYLLGKGARPSHLPARVDRHLSKLTAAEKQELADYLLTFLH", "length": 107, "molWeight": 12221, "crc64": "A8EA341F84BD6C41", "md5": "686E70EC05FD87238092041F4D544B7B"}}
{"primaryAccession": "Q6UN27", "text": "This is Translocator protein protein, from Pig, contains 169 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6UN27", "organism_name": "Pig", "protein_name": "Translocator protein", "length": 169, "firstPublicDate": "2008-04-29", "FUNCTION": "Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial, It is apparently not required for steroid hormone biosynthesis, Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme, Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the TspO/BZRP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPPWLPAVGFTLVPSLGGFLSSRNVLGKGLHWYAGLQKPSWHPPHWTLAPIWGTLYSAMGYGSYMIWKELGGFSEEAVVPLGLYAGQLALNWAWPPLFFGARQMGWALVDLVLTGGVAAATAVAWYQVSPLAARLLYPYLAWLAFAATLNYCVWRDNQGRRGGRRPSE", "length": 169, "molWeight": 18609, "crc64": "DDB680ABF692422F", "md5": "72BC01632BF4ADD6D0A025D8C7AECC1F"}}
{"primaryAccession": "Q6UWY5", "text": "This is Olfactomedin-like protein 1 protein, from Human, contains 402 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6UWY5", "organism_name": "Human", "protein_name": "Olfactomedin-like protein 1", "length": 402, "firstPublicDate": "2004-07-19", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMVALRGASALLVLFLAAFLPPPQCTQDPAMVHYIYQRFRVLEQGLEKCTQATRAYIQEFQEFSKNISVMLGRCQTYTSEYKSAVGNLALRVERAQREIDYIQYLREADECIESEDKTLAEMLLQEAEEEKKIRTLLNASCDNMLMGIKSLKIVKKMMDTHGSWMKDAVYNSPKVYLLIGSRNNTVWEFANIRAFMEDNTKPAPRKQILTLSWQGTGQVIYKGFLFFHNQATSNEIIKYNLQKRTVEDRMLLPGGVGRALVYQHSPSTYIDLAVDEHGLWAIHSGPGTHSHLVLTKIEPGTLGVEHSWDTPCRSQDAEASFLLCGVLYVVYSTGGQGPHRITCIYDPLGTISEEDLPNLFFPKRPRSHSMIHYNPRDKQLYAWNEGNQIIYKLQTKRKLPLK", "length": 402, "molWeight": 45951, "crc64": "FB767C162E8D14D0", "md5": "49CDA34D88F045AACA65B671D0AC4832"}}
{"primaryAccession": "Q6V9X0", "text": "This is Antileukoproteinase protein, from Sheep, contains 132 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6V9X0", "organism_name": "Sheep", "protein_name": "Antileukoproteinase", "length": 132, "firstPublicDate": "2007-03-06", "FUNCTION": "Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G, Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L,major, Down-regulates responses to bacterial lipopolysaccharide (LPS), Plays a role in regulating the activation of NF-kappa-B and inflammatory responses, Has antimicrobial activity against mycobacteria, but not against salmonella, Contributes to normal resistance against infection by M,tuberculosis, Required for normal resistance to infection by L,major, Required for normal wound healing, probably by preventing tissue damage by limiting protease activity (By similarity), Together with ELANE, required for normal differentiation and proliferation of bone marrow myeloid cells (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFSGLFPFLLLALGTLALWAVEGAENEALKAGACPPRKSAQCFGNEKPRCSSDWQCPHKKKCCLDTCGTECLDPVNITNPVKKKPGTCPVIHGQCLMLKPLNHCETDDQCIGALKCCKAMCGKVCLSPVKA", "length": 132, "molWeight": 14197, "crc64": "A8D2A39A1A1DE901", "md5": "A4DD3D09C5FBAAE9D99576D5EA28C16E"}}
{"primaryAccession": "Q71PD7", "text": "This is Histone H2A.V protein, from Zebrafish, contains 128 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q71PD7", "organism_name": "Zebrafish", "protein_name": "Histone H2A.V", "length": 128, "firstPublicDate": "2005-12-06", "FUNCTION": "Variant histone H2A which replaces conventional H2A in a subset of nucleosomes, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, May be involved in the formation of constitutive heterochromatin, May be required for chromosome segregation during cell division (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the histone H2A family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGGKAGKDSGKAKAKAVSRSQRAGLQFPVGRIHRHLKTRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTA", "length": 128, "molWeight": 13509, "crc64": "1F3C388F6854041C", "md5": "132E94E85AAD814968A67DE6B29C6B40"}}
{"primaryAccession": "Q76CY5", "text": "This is Deleted in azoospermia-like protein, from Western clawed frog, contains 286 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q76CY5", "organism_name": "Western clawed frog", "protein_name": "Deleted in azoospermia-like", "length": 286, "firstPublicDate": "2006-09-05", "FUNCTION": "RNA-binding protein that is required for primordial germ cell (PGC) differentiation and indirectly necessary for the migration of PGCs through the endoderm, May promote meiotic cell division during spermatogenesis, Shows a preference for G- and U-rich RNAs and probably binds the 3'-UTR of target mRNAs, Stimulates the initiation of translation of mRNAs through the recruitment of poly(A)-binding proteins (PABPs) (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the RRM DAZ family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSATEASAGEEAASATSQAFVLPEGKVIPNTVFVGGIDITMDEMAIGNLFEKYGKVKDLKIITDRTGVSKGYGFVSFYDEVDVQKIVKSQINFHGKKLKLGPAIRKMQRICTYVQTSPVVISPPTQFHPTWNSQNADSYIQHSPIISPVTQYVQACPYPSSPPMAIQQIPVGCQQPSYFQVSPQWPTDQRNYMFPSPAFTFNYNCCEIDPNGGEPMPREYHIDQAVSASGANLQKRYVDMSTQTIISCLFDPAKKVRLFASQEDYIQDDSVHQFRRSKSVIKRVSN", "length": 286, "molWeight": 31927, "crc64": "257DB58428FB39B8", "md5": "E1D9D917D0B6FCC600BF4EAFAD69F123"}}
{"primaryAccession": "Q76PC7", "text": "This is Probable translation initiation factor, mitochondrial protein, from Fission yeast, contains 233 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q76PC7", "organism_name": "Fission yeast", "protein_name": "Probable translation initiation factor, mitochondrial", "length": 233, "firstPublicDate": "2008-11-04", "FUNCTION": "May be involved in mitochondrial translation initiation", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the IF-3 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNSYLQFPHRKLFIQFSYSLTSVFRKCQSRTFMNSQFASAKLSNSIKKYFDGRIDESIKYQEIFIRGLENKGKLSKTSLVEALARVRAKPETVLYKVADPNENNKYPICSIISYTELSKLRENQSSRLREAEKSKHKNKTRTRYVLFSWRTDVNDIERKLKSVKDFLQDGNIVEIHVQNKKRSQPVSQEVRDSILSKIQLEIEGLGKDMKPPIVNSHSATFLLQPLVSKSSEL", "length": 233, "molWeight": 27042, "crc64": "950CCFA8637A7521", "md5": "C252E4A74C46C5DE241512D47C017477"}}
{"primaryAccession": "Q7SIB8", "text": "This is Plastocyanin protein, from Thick stemmed wood fern, contains 102 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7SIB8", "organism_name": "Thick stemmed wood fern", "protein_name": "Plastocyanin", "length": 102, "firstPublicDate": "2005-02-01", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "AKVEVGDEVGNFKFYPDSITVSAGEAVEFTLVGETGHNIVFDIPAGAPGTVASELKAASMDENDLLSEDEPSFKAKVSTPGTYTFYCTPHKSANMKGTLTVK", "length": 102, "molWeight": 10776, "crc64": "8F061F107483C094", "md5": "67C2AC7FD4DDD9D4DBA48F4A69B6DB40"}}
{"primaryAccession": "Q7T0P4", "text": "This is POC1 centriolar protein homolog A protein, from African clawed frog, contains 441 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q7T0P4", "organism_name": "African clawed frog", "protein_name": "POC1 centriolar protein homolog A", "length": 441, "firstPublicDate": "2012-11-28", "FUNCTION": "May play an important role in centriole assembly and/or stability and ciliogenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the WD repeat POC1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAGQSEDPSLERHFKGHRDTVTAVDFNANTKQLASGSMDSCLMVWNMKTQMRAYRFVGHKDAILSVDFSPSGHLIASASRDKTVRLWVPSVKGESTAFKAHTGTVRSVSFSGDGQSLVTASDDKTIKVWTVHRQKFLFSLNQHINWVRCAKFSPDGRLIVSASDDKTIKLWDKTSRECIQSFCEHGGFVNFVDFHPSGTCIAAAATDNTVKVWDIRMNKLIQHYQVHSGVVNSLSFHPSGNYLITASNDSTLKVLDLLEGRLLYTLHGHQGPVTCVKFSREGDFFASGGSDEQVMVWKTNFDAGSYPDLLKYRQNDTFPSGGDYTSIVQPADVHQPARNAHVTQAADLEPHITEMSVKDRSSPLSYTSRSVDQHHPQAEDGNLQTVASTLEHIVGQLDILTRTVGILEQRLSLTEDKLKECIEQQQATVPPSHSGTKKSSF", "length": 441, "molWeight": 48842, "crc64": "E7226BB1BBCC52AD", "md5": "F186C34BA2C50C7061AA90A0709B1129"}}
{"primaryAccession": "Q84M97", "text": "This is Mechanosensitive ion channel protein 9 protein, from Mouse-ear cress, contains 742 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84M97", "organism_name": "Mouse-ear cress", "protein_name": "Mechanosensitive ion channel protein 9", "length": 742, "firstPublicDate": "2012-01-25", "FUNCTION": "Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the MscS (TC 1,A,23) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAERRVSNGEEVVINVSDKEDSKDPRASPSFNPLASPDSDAGIEKSKPVPPISIPTPEIYKFSGSVHKPPKIPSPEGLVRRKSLSRSIYSKPKSRFGEQQSFRYDSTREENGGRSLREQFGAGSFARGSFDRASPNNKSNRSVASAALSKVAEEEPDENEEIYKKVKLHRVKRSGMKPLAFLELVVFMAILGALIVSLTIDVVNKHTIWGLEFWKWCVLVMVTLSGMLVTNWFMHFVVFIIEKNYLLRKKVLYFVHGLKKNVQVFIWFSLVLIAWICLFDGDVKRTRKTKRFLDFITWTIVSLLVGSILFLVKTFALKVLASKFNVRNFFERIQESVFHQYVLQTLSGPPLIEEAENVGRVPSTGHLSFTRTKDGKVKDKKVIDMGKVHRMKQEKVSAWTMRVLIEAVGTSGISTISSTLDEVNNKKERTDKEITNEMEAVAAAYDVFNNVAKPNHNYIEEDDLLRFMIKEEVDLVLPLIEDADTGKITRKTFTEWVVNVYTSRKTIGHSLNDTKTAVKQLDKLITGILTVITFIVWMVLLDIASTKLLLVFSSQFLGLAFMIGSTCKNIFESFMFVFVMHPYDVGDRCVVDGVMLLVEEIDLLTTVFLKIDNEKVFYPNSVLISKPISNFYRSPDMGDYVDFGIAFSTPAEKIGCLKGKIGEYLVANSQHWYPEAQVMVRAIENMNKLVLNILVQHTINFQVYVEKSLRRTALIIAIKRILEDLEIDYTLLPQDVNLTGHK", "length": 742, "molWeight": 84249, "crc64": "42E588958BAE2F85", "md5": "A265EED2451BD988BB2A10EBB1583D6D"}}
{"primaryAccession": "Q84MM9", "text": "This is Protein MONOCULM 1 protein, from Rice, contains 441 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84MM9", "organism_name": "Rice", "protein_name": "Protein MONOCULM 1", "length": 441, "firstPublicDate": "2004-05-24", "FUNCTION": "Putative transcription regulator that controls rice tillering by initiating axillary buds and promoting their outgrowth, Rice tiller is a specialized grain-bearing branch that is formed on the unelongated basal internode and grows independently of the mother stem (culm) by means of its own adventitious roots", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the GRAS family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRSLHSSSSSDTDNNSGGCKNNGGGGGEAAAAVEGGGDQRAVAAAAPSTRDLLLACADLLQRGDLPAARRAAEIVLAAAASPRGDAADRLAYHFARALALRVDAKAGHGHVVVGGGAARPASSGAYLAFNQIAPFLRFAHLTANQAILEAVDGARRVHILDLDAVHGVQWPPLLQAIAERADPALGPPEVRVTGAGADRDTLLRTGNRLRAFARSIHLPFHFTPLLLSCATTAPHHVAGTSTGAAAAASTAAAATGLEFHPDETLAVNCVMFLHNLAGHDELAAFLKWVKAMSPAVVTIAEREAGGGGGGGDHIDDLPRRVGVAMDHYSAVFEALEATVPPGSRERLAVEQEVLGREIEAAVGPSGGRWWRGIERWGGAARAAGFAARPLSAFAVSQARLLLRLHYPSEGYLVQEARGACFLGWQTRPLLSVSAWQPSSS", "length": 441, "molWeight": 45750, "crc64": "BE678098673077E0", "md5": "3EEA0F2AED9FF759516C5CD5C4BDF1E2"}}
{"primaryAccession": "Q84N49", "text": "This is CRS2-associated factor 1, chloroplastic protein, from Maize, contains 674 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q84N49", "organism_name": "Maize", "protein_name": "CRS2-associated factor 1, chloroplastic", "length": 674, "firstPublicDate": "2007-04-03", "FUNCTION": "Required for the splicing of group IIB introns in chloroplasts, Forms splicing particles with CRS2, Interacts with RNA and confers intron specificity of the splicing particles", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MATARLPSRSFLSPAQQSYPRLPASVRLCLSHHEQPPTGPKRHRRAATSHPAFSAAARGRAKKIPIADTDEPAAGVRVTDRGISYRLDGAPFEFQYSYTEAPRARPVALREAPFMPFGPEATPRPWTGRKPLPKSRKELPEFDSFVLPAPGKKGVKPVQSPGPFLAGMEPRYQSVSREDILGEPLTKEEVSELVKGSLKSKRQLNMGRDGLTHNMLENIHSHWKRKRVCKIKCKGVCTIDMDNICHQLEEKVGGKVIHRQGGVIFLFRGRNYNYRTRPCFPLMLWKPVAPVYPRLVTKVPGGLTPDEATEMRTRGHQLPPICKLGKNGVYANLVNQVREAFEACDLVRVDCSGLNKSDCRKIGAKLKDLVPCILLSFEFEHILMWRGSDWKSSLPPLENSYEVTKVQESFSGKESNEKVTHSGNVLAQIELVSAATSHKNWNLDEGQEKFKDSTDSDMVLNSAKDVPALFHSTGISRTEPSADIPLEYSPLNPVCDIMDPSLNCRSIPTNNCESRALVEKSEHCPDDYNLEMKRKRNDGTKGTVVLNSGSKVEGLLCLLEQAIHSGRALVLSEDELADSDLVYEKSVAFTKSIPRRLVFENTRRKSSARRNVPDNHARTKTHLVENKMLSSPVENKFIVNGGSAMQTIDHGQEFLSDVVHQGTLRVDELAKLLA", "length": 674, "molWeight": 75145, "crc64": "0C3454B196954E56", "md5": "4B160E32CE1667B509081F5C3B593854"}}
{"primaryAccession": "Q86LE4", "text": "This is Defensin protein, from Cattle tick, contains 74 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q86LE4", "organism_name": "Cattle tick", "protein_name": "Defensin", "length": 74, "firstPublicDate": "2010-03-23", "FUNCTION": "Antibacterial peptide mostly active against Gram-positive bacteria", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the invertebrate defensin family, Type 2 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGIYICLVFVLVCGLVSGLADVPAESEMAHLRVRRGFGCPFNQGACHRHCRSIRRRGGYCAGLIKQTCTCYRN", "length": 74, "molWeight": 8249, "crc64": "30B313222AB52952", "md5": "126844434F43CAA91369A1D35C349BD9"}}
{"primaryAccession": "Q8BPC6", "text": "This is Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial protein, from Mouse, contains 396 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8BPC6", "organism_name": "Mouse", "protein_name": "Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial", "length": 396, "firstPublicDate": "2010-11-30", "FUNCTION": "Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate, The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLAVTSCSMKTVLQYAVFLGHSREVVCELVTSFRSFCSHCAVPPSPKYGGRHTVAMIPGDGIGPELMVHVKKIFRSNCVPVDFEEVWVTSTSNEEEINNALMAIRRNRVALKGNIATNHNLPARYKSHNTKFRTILDLYASVVHFKTFPGVMTRHKDIDILVVRENTEGEYTNLEHESVKGVVESLKIVTKTKSVRIADYAFKLAQKMGRKKVTVVHKANIMKLGDGLFLQCCKDVAAHYPQITLESMIIDNTTMQLVSKPQQFDVMVMPNLYGNIINSICTGLVGGSGIVPGANYGDSYAIFEMGSKEIGKDLAHRNIANPVAMLLTSCIMLDYLDLQPYATHIRSAVMASLQNKAVCTPDIGGQGNTASTVEYILHHMKEQTSGCHPNFFLQFT", "length": 396, "molWeight": 43850, "crc64": "1B5D708D2D265398", "md5": "6397773976E5E43343901CD26B0C15DA"}}
{"primaryAccession": "Q8GSP8", "text": "This is Zygote-specific protein 3 protein, from Chlamydomonas smithii, contains 371 amino acids, is soluble, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GSP8", "organism_name": "Chlamydomonas smithii", "protein_name": "Zygote-specific protein 3", "length": 371, "firstPublicDate": "2005-06-21", "FUNCTION": "May have a role in the remodeling of the endoplasmic reticulum upon zygote formation", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLRSAGRVAAVALLALFALGCVSAAAKPSTDRLVAAIKSKNLSAVVDALSVKGLDVNTPDSTRRLPLVEAARSRDARLVGALLDQGALARVSDGTTTPLHLSMQGGSAAIVKLLLAHGADPNAKDKTGASARSTAAAVKELADLLKQWDARGAMAFEDEPGAWIREERDGQSYYWKPANGESRWAVPPSCAWQRVTVQGHPIKYINSLTGQETTRVPPALAWARVTAADGSALWLNWASRVASAAATAPAELPAELAAELAMHPNRRWYNTATREYVYTDPAYATPWRELVDEASGAPFFFNVETGDTTWELPAALAWTEVIESSSGADGESGSGSEAGPRYFHNTVSGEVAWSAPEGSRHVFVEASAADL", "length": 371, "molWeight": 39336, "crc64": "DCC0011986611035", "md5": "F4DC23784FA9C38ACD531678BA57CE45"}}
{"primaryAccession": "Q8GWD5", "text": "This is CASP-like protein 4D1 protein, from Mouse-ear cress, contains 178 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GWD5", "organism_name": "Mouse-ear cress", "protein_name": "CASP-like protein 4D1", "length": 178, "firstPublicDate": "2007-10-23", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the Casparian strip membrane proteins (CASP) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPPPPAPPSVTLRTVLLLLRVLTAAFLLITVVLISTNTVTLEISSTSIKLPFNDVYAYRYMLSAAVIGLVYAVVQLFLTISQFATGKTHPLTYQFDFYGDKVISYLLATGSAAGFGVSKDLKDTYIALIEFDSTDPVDKFFSKGYASASLLLFAFVSLAVLSVFSSLALSKRPVPVS", "length": 178, "molWeight": 19204, "crc64": "30D22E30DAEEEFB2", "md5": "ACC3069828E1A93D8E88268BEEA17450"}}
{"primaryAccession": "Q8IUH2", "text": "This is Protein CREG2 protein, from Human, contains 290 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8IUH2", "organism_name": "Human", "protein_name": "Protein CREG2", "length": 290, "firstPublicDate": "2005-02-15", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the CREG family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSVRRGRRPARPGTRLSWLLCCSALLSPAAGYVIVSSVSWAVTNEVDEELDSASTEEAMPALLEDSGSIWQQSFPASAHKEDAHLRPRAGAARARPPPAPPGMFSYRREGGQTASAPPGPRLRAATARSLAHASVWGCLATVSTHKKIQGLPFGNCLPVSDGPFNNSTGIPFFYMTAKDPVVADLMKNPMASLMLPESEGEFCRKNIVDPEDPRCVQLTLTGQMIAVSPEEVEFAKQAMFSRHPGMRKWPRQYEWFFMKMRIEHIWLQKWYGGASSISREEYFKAVPRKA", "length": 290, "molWeight": 32109, "crc64": "70E9DBC6FCE3BD64", "md5": "EF5163D5703C80343A15A9EDD6A3590F"}}
{"primaryAccession": "Q8LDV3", "text": "This is Uncharacterized protein At4g13200, chloroplastic protein, from Mouse-ear cress, contains 185 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LDV3", "organism_name": "Mouse-ear cress", "protein_name": "Uncharacterized protein At4g13200, chloroplastic", "length": 185, "firstPublicDate": "2007-05-15", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSSFTIPSPSSFSLSNSYNQTSPHSFTLRNSRSNFEFHRLRLDVESRRRSTSLRSNCSTKGTDSGENENKSVLDAFFLGKALAEVINERIESTVGEVLSTIGKFQAEQQKQVQEIQEEVLERAKKAKERAARETMEEQGLVASKPVAITRNPDAVVVASVTSTSTVESKTIMVDVEESSSSSDED", "length": 185, "molWeight": 20430, "crc64": "EA85AB07D363C592", "md5": "6D7614166BCF60D126C36C4970D23076"}}
{"primaryAccession": "Q8LFC0", "text": "This is Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial protein, from Mouse-ear cress, contains 367 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LFC0", "organism_name": "Mouse-ear cress", "protein_name": "Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial", "length": 367, "firstPublicDate": "2007-01-09", "FUNCTION": "Performs an essential role in the oxidative function of the citric acid cycle", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRRSLTLLKNLARNANGSGIQTRSVTYMPRPGDGAPRAVTLIPGDGIGPLVTNAVEQVMEAMHAPIFFEKYDVHGEMSRVPPEVMESIRKNKVCLKGGLKTPVGGGVSSLNVQLRKELDLFASLVNCFNLPGLPTRHENVDIVVIRENTEGEYAGLEHEVVPGVVESLKVITKFCSERIAKYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCREVAKKYPSITYNEIIVDNCCMQLVAKPEQFDVMVTPNLYGNLVANTAAGIAGGTGVMPGGNVGADHAVFEQGASAGNVGKDKIVLENKANPVALLLSSAMMLRHLQFPSFADRLETAVKKVIAEGKCRTKDLGGTSTTQEVVDAVIAKLD", "length": 367, "molWeight": 39627, "crc64": "62DF327529961082", "md5": "3607F6F9C208ADC97DEDB2D49BC8D3C3"}}
{"primaryAccession": "Q8LPW2", "text": "This is Small ribosomal subunit protein uS13m protein, from Soybean, contains 148 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LPW2", "organism_name": "Soybean", "protein_name": "Small ribosomal subunit protein uS13m", "length": 148, "firstPublicDate": "2003-06-27", "FUNCTION": "Located at the top of the head of the small subunit, it contacts several helices of the 18S rRNA", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uS13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFGSARILSDVTLRLRQNLSVHGVRVQNINIGGGVGGEIPDNKRLVYALQNLHGIGRSKAQHIVAELGVENKFVKDLSKRELYSIRELLSKYLIGNDLKKCVERDVGRLVGIQCYRGIRHVDSLPCRGQRTHTNARTRRSRKTFSGSR", "length": 148, "molWeight": 16663, "crc64": "ECAFD8697DCCDE5A", "md5": "A76F5DA3D22B0E57A4D6B54A95997C11"}}
{"primaryAccession": "Q8MIR0", "text": "This is L-threonine 3-dehydrogenase, mitochondrial protein, from Pig, contains 373 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8MIR0", "organism_name": "Pig", "protein_name": "L-threonine 3-dehydrogenase, mitochondrial", "length": 373, "firstPublicDate": "2007-08-21", "FUNCTION": "Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate, mediating L-threonine catabolism", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the NAD(P)-dependent epimerase/dehydratase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPVVKMLKQVASRTLGSPACGCQPPTLPRRFLGTSPRQIPADANFHSTSFSEANQPRVLITGGLGQLGVGLASLLRKRFGKDNVILSDIRKPPEHVFLSGPFIYSDILDYKNLREIVVNNRVTWLFHYSALLSAVGEANVSLARAVNITGLHNVLDVAAEHGLRLFVPSTIGAFGPTSPRNPTPDLCIQRPRTIYGVSKVHAELMGEYYYYRYGLDFRCLRYPGIISADSQPGGGTTDYAVQIFQDAVKNGRFECNLNPGTKLPMMYIDDCLRATLEVMEAPAEALSLRTYNVNAMSFTPAELAQEVLKHIPEFQITYNVDSVRQAIADSWPMNFDDSTARRDWGWKHDFDLPELVTTMLNFHGAHSRVAQAN", "length": 373, "molWeight": 41432, "crc64": "6F3CCB6879E66480", "md5": "31B5ECD905A4979B27D90304D9622431"}}
{"primaryAccession": "Q8MUG0", "text": "This is Lectizyme protein, from Riverine tsetse fly, contains 274 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8MUG0", "organism_name": "Riverine tsetse fly", "protein_name": "Lectizyme", "length": 274, "firstPublicDate": "2007-06-26", "FUNCTION": "Protein with lectin and protease activity involved in the establishment of trypanosome infections in tsetse flies, Binds D-glucosamine and agglutinates bloodstream-form trypanosomes and rabbit red blood cells, Capable of inducing transformation of bloodstream-form trypanosomes into procyclic (midgut) forms in vitro", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase S1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFFAVFALCVASVSAANLDAIAKPGFPAGRIINGHEADKGEAPFIVSLKAGKGHFCGGSIIAENWVLTAGHCLIFDEFEIVAGLHSRNDESDVQIRKVTGKHQQIVHEKYGGGVGPNDIGLIYVDKPFNLNALTRDGTAAVAKVNLPTGKYESTGKGKLYGWGLDNSGFSPNILNTLDVDIIGYEECKNALNSDDPLDPVNICSYTAGAIDGACNGDSGGPMVRITPDGTELVGIVSWGYQPCASTTMPSVYTWTSAFDKWIEDSIKNYAQLL", "length": 274, "molWeight": 29180, "crc64": "1EC4A00D3DDCD5AB", "md5": "4F9A73205204DC1E71FE4E8CA60BD1F3"}}
{"primaryAccession": "Q8MVA6", "text": "This is Antimicrobial peptide ISAMP protein, from Black-legged tick, contains 69 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8MVA6", "organism_name": "Black-legged tick", "protein_name": "Antimicrobial peptide ISAMP", "length": 69, "firstPublicDate": "2010-03-02", "FUNCTION": "Has antimicrobial activity against B,cereus (MIC=5,8 ug/ml), B,subtilis (MIC=12,3 ug/ml), S,aureus (MIC=10,4 ug/ml), E,coli Edl 933 (MIC=3,2 ug/ml) and E,coli MG/655 (MIC=4,2 ug/ml), Non-hemolytic", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRAVAIFIVTLLVLECVYFVMSEPDPGQPWQVKAGRPPCYSIPCRKHDECRVGSCSRCNNGLWGDRTCR", "length": 69, "molWeight": 7817, "crc64": "EBB93FDBFA754E24", "md5": "866E53FBFC3DDD3E8B983B2B850E0F9E"}}
{"primaryAccession": "Q8NEC7", "text": "This is Glutathione S-transferase C-terminal domain-containing protein protein, from Human, contains 633 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8NEC7", "organism_name": "Human", "protein_name": "Glutathione S-transferase C-terminal domain-containing protein", "length": 633, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the GSTCD family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSRDSSLLRDDLIQDVEIQIISRQELPPIVQNCCLPAVVERSDNFCRAGLAVVLRHIIQKSYEADPLKKELLELLGFKKTCLKACAEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGGPRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNIWFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFPKSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQVISMEPESCSPKNNMIVGVPI", "length": 633, "molWeight": 71079, "crc64": "709B8EA78BF0E732", "md5": "CFC32B3972DBBBBCE762E8E6423E4BC7"}}
{"primaryAccession": "Q8R4E4", "text": "This is Myozenin-3 protein, from Mouse, contains 245 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8R4E4", "organism_name": "Mouse", "protein_name": "Myozenin-3", "length": 245, "firstPublicDate": "2005-11-22", "FUNCTION": "Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere, Plays an important role in the modulation of calcineurin signaling, May play a role in myofibrillogenesis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the myozenin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIPKEQKEPVMAVPGDLAEPVPSLDLGKKLSVPQDLMIEELSLRNNRGSLLFQKRQRRVQKFTFELSESLQAILASSARGKVAGRAAQATVPNGLEEQNHHSETHVFQGSPGDPGITHLGAAGTGSVRSPSALAPGYAEPLKGVPPEKFNHTAIPKGYRCPWQEFTSYQDYSSGSRSHTPIPRDYRNFNKTPVPFGGPHVREAIFHAGTPFVPESFSGLELLRLRPNFNRVAQGWVRKLPESEEL", "length": 245, "molWeight": 26982, "crc64": "CF3FB6C4114FF03E", "md5": "60EDDBD24F5215FF63D8EBE815FB3672"}}
{"primaryAccession": "Q8R4V5", "text": "This is Oncoprotein-induced transcript 3 protein protein, from Mouse, contains 546 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8R4V5", "organism_name": "Mouse", "protein_name": "Oncoprotein-induced transcript 3 protein", "length": 546, "firstPublicDate": "2007-08-21", "FUNCTION": "May be involved in hepatocellular function and development", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPLSLLLTCLSTTVTLVSPAVLDPCSAYISLNEPWRNTDHQFDESQNQPLCDNHMNGEWYRFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEEDGIVQRQACASFKGNCCLWNATVEVKACPRGYYVYRLARPSVCFHVYCGHFYDICDEDCHGNCLDTTECACSPGTSLGPDGQTCFDENECEHNNGGCSEICVNLKNSHRCACGVGRVLRSDGKTCEDIEGCHNNNGGCSHSCLGSEEGYQCECPRGLVLSEDNHTCQVPVLCKSSAIEVSVPRELVGGLELFLTNTSCRGVSNGTHVNIVFSLKTCGTVVDVVNDKIVASNIVTGLPKETPGSSGDIIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNAPLEIRSRNHGIFPFTLEIFKDHEFEEPYRETLPTLKLRDSLYFGIEPLVHVNGLESLVESCFATPTAKMDEILKYYLIQDGCVSDDSVKQYSSRDHLAKHFQAPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRVRREVGEDEDSAGLQSQTLTGGPIAIDWED", "length": 546, "molWeight": 60316, "crc64": "B669D7FBD3105295", "md5": "7ADFD9C1AD52402BE9114D7A1E0DBA9B"}}
{"primaryAccession": "Q8RVC7", "text": "This is Sulfate permease 1, chloroplastic protein, from Chlamydomonas smithii, contains 411 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8RVC7", "organism_name": "Chlamydomonas smithii", "protein_name": "Sulfate permease 1, chloroplastic", "length": 411, "firstPublicDate": "2012-09-05", "FUNCTION": "Part of the ABC-type chloroplast envelope-localized sulfate transporter, Required for primary uptake and assimilation of sulfate and chloroplast protein biosynthesis", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the ATP-binding cassette (ABC) (TC 3,A,1) superfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MERVCSHQLASSRGRPCIAGVQRSPIRLGTSSVAHVQVSPAGLGRYQRQRLQVVASAAAAAAFDPPGGVSAGFSQPQQQLPQQHPRQPQAVAEVAVAESVSAPASAAPSNDGSPTASMDGGPSSGLSAVPAAATATDLFSAAARLRLPNLSPIITWTFMLSYMAFMLIMPITALLQKASLVPLNVFIARATEPVAMHAYYVTFSCSLIAAAINCVFGFVLAWVLVRYNFAGKKILDAAVDLPFALPTSVAGLTLATVYGDEFFIGQFLQAQGVQVVFTRLGVVIAMIFVSFPFVVRTMQPVMQEIQKEMEEAAWSLGASQWRTFTDVVLPPLLPALLTGTALAFSRALGEFGSIVIVSSNFAFKDLIAPVLIFQCLEQYDYVGATVIGTVLLLISLVMMLAVNQLQKLARK", "length": 411, "molWeight": 43709, "crc64": "1540B14133E9C867", "md5": "3C2F1D4D77361AFEA203E7B01486CCB8"}}
{"primaryAccession": "Q8SRA2", "text": "This is ADP,ATP carrier protein 1 protein, from Microsporidian parasite, contains 559 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8SRA2", "organism_name": "Microsporidian parasite", "protein_name": "ADP,ATP carrier protein 1", "length": 559, "firstPublicDate": "2009-09-01", "FUNCTION": "ATP transporter involved in the uptake of ATP from the host cell cytoplasm, Provides the microsporidian cell with host ATP in exchange for ADP, This is an obligate exchange system, This energy acquiring activity is an important component of microsporidian parasitism", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the ADP/ATP translocase tlc family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNEVENNNHSFPREDIPTEDEIEEEANSRQGILRYFRVARAEYTKFALLGLMFGIIGFIYSFMRILKDMFVMVRQEPTTILFIKIFYILPVSMALVFLIQYMLGTKTVSRIFSIFCGGFASLFFLCGAVFLIEEQVSPSKFLFRDMFIDGKMSSRSLNVFKSMFLTLNEPLATIVFISAEMWGSLVLSYLFLSFLNESCTIRQFSRFIPPLIIITNVSLFLSATVAGAFFKLREKLAFQQNQVLLSGIFIFQGFLVVLVIFLKIYLERVTMKRPLFIVSSGSRRKKAKANVSFSEGLEIMSQSKLLLAMSLIVLFFNISYNMVESTFKVGVKVAAEYFNEEKGKYSGKFNRIDQYMTSVVVICLNLSPFSSYVETRGFLLVGLITPIVTLMAIVLFLGSALYNTSMEESGLGIVNGLFPGGKPLYVLENYFGVIFMSLLKITKYSAFDICKEKLGMRINPTYRARFKSVYDGIFGKLGKSIGSIYGLLMFEALDTEDLRKATPITAGIIFIFIVMWVKAIIYLSRSYESAVQHNRDVDIDMTEKAKKSLETPEEPKVVD", "length": 559, "molWeight": 63516, "crc64": "9B15588ED28BCD5D", "md5": "52ED5F6A80DB2EA7F2B7E9A0872274BF"}}
{"primaryAccession": "Q8SUF9", "text": "This is ADP,ATP carrier protein 2 protein, from Microsporidian parasite, contains 553 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8SUF9", "organism_name": "Microsporidian parasite", "protein_name": "ADP,ATP carrier protein 2", "length": 553, "firstPublicDate": "2009-09-01", "FUNCTION": "ATP transporter involved in the uptake of ATP from the host cell cytoplasm, Provides the microsporidian cell with host ATP in exchange for ADP, This is an obligate exchange system, This energy acquiring activity is an important component of microsporidian parasitism", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the ADP/ATP translocase tlc family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSEIGSSVPVNENRPLLTEDEVEAQANSSTVWPLSRIRVARCEWKLWGSLAFIFGASAYIYSFSRVMKDSFVLSRQLPIAISFLKTCFVLPISVIVTGIVQKLLVTRTISKVFDYTLIAFSFLYLLIGMVLLPFAEKIQPGLYFSRDIFADDKMAYKGFEFLFAIFLIFNEWTTSFVYVCAELFGSLVVQFMFLAFANEALTIRQSTRMMPLFYVISNILLLLSSESTSFYSKKVREWDYKKTCLITNSFFAVFGAMIAVTYLVKKYAENTILKKQLFIRTEGVAKKKGRKSSAGFSESMKLMAQSKFLVAMVMNALFYYAGTNLIESSWKNGISVAADANNMEKRAYSASIVSGEQRVVGALVAIILLTPISTLVQTHGWITMAIVPPLVTLVSSLVIFGSAFFNYSNYPEGKTSVILSSLVKGYKPNFYLECNIGIYCVSGMKIAKYAFYDISKEAISLQIDPLYRPRLKAVYDGLCGKLGKSIGSLYAMFWSVMGYNDVRAAAPITLGMWLIISPIWIYSVIYLNRKYNQSIQTSSPIDLDLFSGKKDLE", "length": 553, "molWeight": 62160, "crc64": "5091200D1F656BF5", "md5": "7A6B788F1FAC76A870BB9C299260DE21"}}
{"primaryAccession": "Q8SUG7", "text": "This is ADP,ATP carrier protein 4 protein, from Microsporidian parasite, contains 536 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8SUG7", "organism_name": "Microsporidian parasite", "protein_name": "ADP,ATP carrier protein 4", "length": 536, "firstPublicDate": "2009-09-01", "FUNCTION": "ATP transporter involved in the uptake of ATP from the host cell cytoplasm, Provides the microsporidian cell with host ATP in exchange for ADP, This is an obligate exchange system, This energy acquiring activity is an important component of microsporidian parasitism", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the ADP/ATP translocase tlc family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSENREIDATDRRDKTFDKEKLRPHVYSSVAGGMRSTSGDTKAVLLFSLLFALLSYIDAFLYVLGDMVMMNTQMPSSILFIKSVLVLPMTFFFIVIVQKGLRYLSQPRMLEVILIISSVFFLLFGFVIWPYCKRLQPDFFWSRDIFSDGKMKTRHLDFFFPIFLVFSEWASTMLYLVAELWGSLIISFMFFSRAIHQCTEAQVKKFLPTISLISAVVFLSSGLLTKSLNSRRDALPYHEKERLFSQVFIVTSALTVMSAITSFFTDRALAKDDPRHKGKKEHKVRKIGFAGSLKMMQKSRFLRAMTESVVAASVCSNIFEAIYRGGIVLGAVQSSTSKSSYMNRLNAMAQIITSIFLLVMFFKPATHLIERRGWFPVAITAPIVAIITLVLFFPMVFFNNITEGDLIASGEEYVGSFVLENYTGMFLTTIIRISKYCFFDVAKEAASIRVSPVHRHSFRGIHDGLGINIGKTIGSVYCTLVTVVFDVRDVRNVVSVSTVFVGVFCVIWIRSILHINKKYKESIERNDFINVELAEG", "length": 536, "molWeight": 60856, "crc64": "667A534F9D5D814A", "md5": "03EE7529A40635B609F791F4F827F443"}}
{"primaryAccession": "Q8TDS7", "text": "This is Mas-related G-protein coupled receptor member D protein, from Human, contains 321 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8TDS7", "organism_name": "Human", "protein_name": "Mas-related G-protein coupled receptor member D", "length": 321, "firstPublicDate": "2004-07-19", "FUNCTION": "May regulate nociceptor function and/or development, including the sensation or modulation of pain, Functions as a specific membrane receptor for beta-alanine, Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor, Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i)", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family, Mas subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNQTLNSSGTVESALNYSRGSTVHTAYLVLSSLAMFTCLCGMAGNSMVIWLLGFRMHRNPFCIYILNLAAADLLFLFSMASTLSLETQPLVNTTDKVHELMKRLMYFAYTVGLSLLTAISTQRCLSVLFPIWFKCHRPRHLSAWVCGLLWTLCLLMNGLTSSFCSKFLKFNEDRCFRVDMVQAALIMGVLTPVMTLSSLTLFVWVRRSSQQWRRQPTRLFVVVLASVLVFLICSLPLSIYWFVLYWLSLPPEMQVLCFSLSRLSSSVSSSANPVIYFLVGSRRSHRLPTRSLGTVLQQALREEPELEGGETPTVGTNEMGA", "length": 321, "molWeight": 36118, "crc64": "B45AB7FEB2154B40", "md5": "9A655E8C5C7288429DFA080CF7D919A7"}}
{"primaryAccession": "Q8TG42", "text": "This is Cell wall mannoprotein 1 protein, from Aspergillus flavus, contains 273 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8TG42", "organism_name": "Aspergillus flavus", "protein_name": "Cell wall mannoprotein 1", "length": 273, "firstPublicDate": "2015-04-29", "FUNCTION": "Constitutive protein of the cell wall (By similarity), Antigen target of host humoral immune response", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the cell wall mannoprotein 1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRFSAIFTLGLAGTALATPLVERAGSSPTDIISGISDKTDALDSAIKAYNGGDPSKVESASADLISTITKGTDAIKSGDDISTTDALALPEPVQALTKKVEQAIDDIIAKKDKFVEAGAGGKVKDSLNQQKSAADGLASAITSKVPESLKEIAQSLSAGISTAIQKGVDAYKDVSDSAPSSSAGSSASATATGSASETGSASTTGSASATSSSVIPTSSGAASSSAAPSGSSTPTGSGSASATSPPLATGAANKATIGYSLGAVAMAAIAVAV", "length": 273, "molWeight": 26281, "crc64": "8390EA782A502EB4", "md5": "0163A95A267372A036E2B978E0956256"}}
{"primaryAccession": "Q8WNR4", "text": "This is Histone H2B subacrosomal variant protein, from Bovine, contains 122 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8WNR4", "organism_name": "Bovine", "protein_name": "Histone H2B subacrosomal variant", "length": 122, "firstPublicDate": "2006-07-11", "FUNCTION": "May act as an acrosome-nuclear docking protein in sperm", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the histone H2B family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MARNVTKRNKRCRGHQKAIYKKKSHSSSESGLRNYSLYINRVLKEVVPQKGISSRTIDIINTMINDMFERISTEACNLMYYRKRCTLTPEDIEKAVYLLLPEKLAKYAVAFGKEAVQRYVRS", "length": 122, "molWeight": 14224, "crc64": "9149BA61CB85F7B0", "md5": "11A8A986DD06ABBCFFF67DAB23B8EFDE"}}
{"primaryAccession": "Q8X1T0", "text": "This is DeSI-like protein sdu1 protein, from Fission yeast, contains 201 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8X1T0", "organism_name": "Fission yeast", "protein_name": "DeSI-like protein sdu1", "length": 201, "firstPublicDate": "2004-08-31", "FUNCTION": "Has a role in meiosis", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the DeSI family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKVYINVYDLMPDSPVNKLAWTLGLGIYHTGLVLEGKEYAFGAHEIPGSTGVFATMPRPPLEGCRWRCSIALPNCTLPKPDVDRILIRLSQEFTGLSYSLLERNCNHFTNAAAIELTGSPIPSFLNRISRIGLAFPTITNALLQHGQKNTSDVDDSSDSSSDVDEETLIVSKSKKAHKDIPKFSAPPPSADLNNLITDSLP", "length": 201, "molWeight": 21952, "crc64": "62E5C740AD790361", "md5": "04B1394078DE2E1BA74615E7164DE8A2"}}
{"primaryAccession": "Q90WV8", "text": "This is Insulin-like growth factor-binding protein 5 protein, from African clawed frog, contains 265 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q90WV8", "organism_name": "African clawed frog", "protein_name": "Insulin-like growth factor-binding protein 5", "length": 265, "firstPublicDate": "2006-02-21", "FUNCTION": "IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture, They alter the interaction of IGFs with their cell surface receptors, Promotes anterior neural development by stimulating insulin growth factor (IGF) signaling via IGF receptors", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEMLLPMCLLLVSLCLGQCQALGSFVHCEPCDDKAMSMCPPTPVGCELVKEPGCGCCMTCALAEGHRCGVYTEHCAKGLRCLPEQGEEKPLHALLHGRGVCLNLKNHRDQSKIDRESREEDPTTSETEDIYQSKHRGKMRLSDQKAIALNTFRQKKHSQSRIVSVEKVQSPSTPEHSIEIDMGPCRRQVETLMQEMKLSHRVYPRAFYLPNCDRKGFYKRKQCKPSRGRKRGLCWCVDKYGLKLPGIDYVNGDLQCHSFDSSNTE", "length": 265, "molWeight": 29995, "crc64": "E0B943382778A8DA", "md5": "91E63818D3488AD20931E0B46772DD8B"}}
{"primaryAccession": "Q90ZD5", "text": "This is Chordin-like protein 1 protein, from Chicken, contains 456 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q90ZD5", "organism_name": "Chicken", "protein_name": "Chordin-like protein 1", "length": 456, "firstPublicDate": "2003-01-17", "FUNCTION": "Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRRKWRSEDFHFVFFGVLCLLLIDRGKLEQVKHSDTYCVFQDKKYRVGERWHPYLEPYGLVYCVNCLCSENGNVLCSRIRCPSLHCPSPVHVPQLCCPRCPEDSLFSVSSKITGKSCEYNGTTYHHGEMFVAEGLFQNRQANQCAQCSCSEGNVYCGLKTCPKLTCSFPVSVPESCCPVCRGDGELSWEQADGDIFRQPANREARHSYHRPHYELSPSSTRQVVNVPRFPSARSNRGVLPDPQQASGTIVQIVINNKHKHGRVCVSNGKTYSHGESWHPNLRAFGIVECVLCTCNITKQECKKIHCPEQYPCKYPQKVEGKCCKVCPEEVPSQSFDNKDYFCGKETFPVYESIFTEEGETIRKIAVETEKPPQIEIHVWTIRKGILRHFYIEKMSKREFEELPYFKQITRTTSSQWKIFSEGEAQISQMCESRVCRTELEDLVKVLYLEKSEKGHC", "length": 456, "molWeight": 52399, "crc64": "D54F6685F3839BC6", "md5": "5796FC9E82FFD634D18C98935728E757"}}
{"primaryAccession": "Q91WW2", "text": "This is Mas-related G-protein coupled receptor member A4 protein, from Mouse, contains 313 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91WW2", "organism_name": "Mouse", "protein_name": "Mas-related G-protein coupled receptor member A4", "length": 313, "firstPublicDate": "2004-07-19", "FUNCTION": "Orphan receptor, May be a receptor for RFamide-family neuropeptides such as NPFF and NPAF, which are analgesic in vivo, May regulate nociceptor function and/or development, including the sensation or modulation of pain", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family, Mas subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPTTTNPMNETIPGSIDIETLIPNLMIIIFGLVGLTGNVILFWLLGFHLHRNAFLVYILNLALADFLFLLCHIINSTMLLLKVHLPNNILNHCFDIIMTVLYITGLSMLSAISTERCLSVLCPIWYRCRRPEHTSTVLCAVIWFLPLLICILNGYFCHFFGPKYVIDSVCLATNFFIRTYPMFLFIVLCLSTLALLARLFCGAGKTKFTRLFVTIMLTVLVFLLCGLPLGFFWFLVPWINRDFSVLDYILFQTSLVLTSVNSCANPIIYFFVGSFRHRLKHKTLKMVLQSALQDTPETPENMVEMSRSKAEP", "length": 313, "molWeight": 35682, "crc64": "A428C370BBD0F202", "md5": "7EE74E2B8042B78329007040D862A399"}}
{"primaryAccession": "Q91WW5", "text": "This is Mas-related G-protein coupled receptor member A1 protein, from Mouse, contains 304 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91WW5", "organism_name": "Mouse", "protein_name": "Mas-related G-protein coupled receptor member A1", "length": 304, "firstPublicDate": "2004-07-19", "FUNCTION": "Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide, Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system, Its effect is mediated by G(q) and G(11) proteins, May regulate the function of nociceptive neurons by modulation of pain perception", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the G-protein coupled receptor 1 family, Mas subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDNTIPGGINITILIPNLMIIIFGLVGLTGNGIVFWLLGFCLHRNAFSVYILNLALADFFFLLGHIIDSILLLLNVFYPITFLLCFYTIMMVLYIAGLSMLSAISTERCLSVLCPIWYHCHRPEHTSTVMCAVIWVLSLLICILNSYFCGFLNTQYKNENGCLALNFFTAAYLMFLFVVLCLSSLALVARLFCGTGQIKLTRLYVTIILSILVFLLCGLPFGIHWFLLFKIKDDFHVFDLGFYLASVVLTAINSCANPIIYFFVGSFRHRLKHQTLKMVLQNALQDTPETAKIMVEMSRSKSEP", "length": 304, "molWeight": 34381, "crc64": "C56CBF879067A52B", "md5": "557A6C15723DC6613B1D79D52EAB4F75"}}
{"primaryAccession": "Q91YJ3", "text": "This is Thymocyte nuclear protein 1 protein, from Mouse, contains 226 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91YJ3", "organism_name": "Mouse", "protein_name": "Thymocyte nuclear protein 1", "length": 226, "firstPublicDate": "2006-11-28", "FUNCTION": "Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPRPRKRQTGTAGPDRKKLSGKRTKTENSESTSVKLENSSLEMTTTFKNGGKNLSNYWLMKSEPESRLEKGIDMKFSIEDLKAQPKQTACWDGVRNYQARNFLRAMKLEDEAFFYHSNCKQPGIVGLMKIVKEAYPDHTQFEKSNPHYDPSSKEDDPKWSMVDVQFVRMMKRFIPLEELKTYHQAHKATGGPLKSMTLFTRQRLSVQPLTQEEFDFILSLEETEPS", "length": 226, "molWeight": 26178, "crc64": "57D69619D37CDF89", "md5": "18CBF62965D5CEE42BC1D507C1AC9198"}}
{"primaryAccession": "Q91ZU1", "text": "This is Ankyrin repeat and SOCS box protein 6 protein, from Mouse, contains 418 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91ZU1", "organism_name": "Mouse", "protein_name": "Ankyrin repeat and SOCS box protein 6", "length": 418, "firstPublicDate": "2003-02-28", "FUNCTION": "Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ankyrin SOCS box (ASB) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPFLHGFRRIIFEYQPLVDAILGALGIQDLERQEPLDDSASSEESRILVLTELLEQKAHSPFYQEGVSNALLKMAELGLTRAAAVLLQSGANLNFEDPVTYYTALHIAVLRNQPDMVELLVRHGADINRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKNGKTALLHALASSDGVQIHNTENIRLLLEGGADVKATTKDGDTVFTCIIFLLGETVCGDKEEAPMINRFCFQVTQLLLAHGADPSECPAHESLTHICLKSFKLHFPLLCFLLESGAAYNCSLHGASCWSGFNLVFERLCSHPGCAEDDSHIELLHKAETVLDLMVTSSQRLQLPENLNIHPVGSLAGKIQALHASLRQLESYPPPLKHLCRVSIRLCLRPWPVDTKVKALPLPDRLKWYLLSAHSDTQDTC", "length": 418, "molWeight": 46276, "crc64": "04ADE4CC0CF6E964", "md5": "6B17A626D76B24573F8DA2CBFDBCAE8A"}}
{"primaryAccession": "Q920N1", "text": "This is Outer dense fiber protein 3 protein, from Mouse, contains 254 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q920N1", "organism_name": "Mouse", "protein_name": "Outer dense fiber protein 3", "length": 254, "firstPublicDate": "2007-09-11", "FUNCTION": "Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail, May help to maintain the passive elastic structures and elastic recoil of the sperm tail", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ODF3 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAEEVWMGTWRPHRPRGPIMALYSSPGPKYLIPPTTGFVKHTPTKLRAPAYSFRGAPMLLAENCSPGPRYSVNPKILKTGKDLGPAYSILGRYHTKTLLTPGPGDYFPEKSTKYVFDSAPSHSISARTKTFRVDSTPGPAAYMLPVVMGPHTVGKVSQPSFSIKGRSKLGSFSDDLHKTPGPAAYRQTEVQVTKFKAPQYTMAARVEPPGDKTLKPGPGAHSPEKVTLNKPCAPTVTFGIKHSDYMTPLVVDVE", "length": 254, "molWeight": 27650, "crc64": "D9621C6A1411368C", "md5": "CA0059F89F99FA6B597CD0A7BDF43D8F"}}
{"primaryAccession": "Q925D4", "text": "This is Transmembrane protein 176B protein, from Rat, contains 263 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q925D4", "organism_name": "Rat", "protein_name": "Transmembrane protein 176B", "length": 263, "firstPublicDate": "2007-03-06", "FUNCTION": "Required for the development of cerebellar granule cells (By similarity), May play a role in the process of maturation of dendritic cells", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the TMEM176 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAQATVTVDGVKVTSTRPQSAQISIHIHHKSALEQLLGAMGSLKKFLSYPQARIHYGQLSLGVTQILLGLVSCVLGVCLYFGPWTELCASGCAFWSGSVAILAGVGIVIHEMGQGKLSGHISRLLLLACSATAAAATVMGVKSLIWQTSASYYFEISSTCDSLQPSIVDRFRSVRFTDDSDWRTERCREYLRMMMNLFLAFCILFTVICILKIVVSVASLGLSLRSMCGRNSQVLNDEETEKKLLGGDSAPASPTKEKIPVTP", "length": 263, "molWeight": 28485, "crc64": "49F231E020A2DE31", "md5": "5181E647B4499882B9E14C6A9EDB0C6B"}}
{"primaryAccession": "Q93ZS9", "text": "This is Zinc finger CCCH domain-containing protein 47 protein, from Mouse-ear cress, contains 580 amino acids, has 2 C3H1-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [251, 278], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}, {"location": [286, 310], "description": "C3H1-type", "keyword_description": "Zinc finger", "textural_description": "C3H1-type Zinc finger"}], "meta_data": {"primaryAccession": "Q93ZS9", "organism_name": "Mouse-ear cress", "protein_name": "Zinc finger CCCH domain-containing protein 47", "length": 580, "firstPublicDate": "2009-05-05", "FUNCTION": "Involved in salt stress response, May positively modulate plant tolerance to salt stress", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C3H1-type Zinc finger": 2}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MCSGPKSNLCSSRTLTEIESRQKEEETMLLLEFAACDDLDSFKREVEEKGLDLDESGLWYCRRVGSKKMGLEERTPLMVAAMYGSIKVLTFIVSTGKSDVNRACGEERVTPLHCAVAGCSVNMIEVINVLLDASALVNSVDANGNQPLDVFVRVSRFVASPRRKAVELLLRGGGVGGLIDEAVEEEIKIVSKYPADASLPDINEGVYGSDEFRMYSFKVKPCSRAYSHDWTECAFVHPGENARRRDPRKYPYTCVPCPEFRKGSCPKGDSCEYAHGVFESWLHPAQYKTRLCKDETGCARKVCFFAHKREEMRPVNASTGSAVAQSPFSSLEMMPGLSPLAYSSGVSTPPVSPMANGVPSSPRNGGSWQNRVNTLTPPALQLNGGSRLKSTLSARDIDMEMEMELRLRGFGNNVEETFGSYVSSPSRNSQMGQNMNQHYPSSPVRQPPSQHGFESSAAAAVAVMKARSTAFAKRSLSFKPATQAAPQSNLSDWGSPNGKLEWGMKGEELNKMRRSVSFGIHGNNNNNAARDYRDEPDVSWVNSLVKDSTVVSERSFGMNERVRIMSWAEQMYREKEQTVV", "length": 580, "molWeight": 64058, "crc64": "A6238A3165DA626F", "md5": "D4CFF99BE9297214F675546EDE78DCA7"}}
{"primaryAccession": "Q941D3", "text": "This is Probable plastid-lipid-associated protein 8, chloroplastic protein, from Mouse-ear cress, contains 239 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q941D3", "organism_name": "Mouse-ear cress", "protein_name": "Probable plastid-lipid-associated protein 8, chloroplastic", "length": 239, "firstPublicDate": "2007-06-12", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the PAP/fibrillin family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAATASSLTIASSFSEPRTQIHSSRRLNLPLQYSIPYKVLRSRSRRLGLVVSSVSAPNVELRTGPDDLISTLLSKVANSDGGVTLSPEQHKEVAQVAGELQKYCVKEPVKNPLIFGDWEVVYCSRPTSPGGGYRSVIGRLFFKTKEMIQAIDAPDIVRNKVSINAFGFLDGDVSLTGKLKALDSEWVQVIFEPPEIKVGSLEFKYGFESEVKLRITYVDEKLRLGLGSKGSLFVFRRRQ", "length": 239, "molWeight": 26482, "crc64": "541ECE11BBFBE2F1", "md5": "0B9DB728EA17F38672F17ABA520229AB"}}
{"primaryAccession": "Q944N1", "text": "This is Chromo domain protein LHP1 protein, from Tomato, contains 399 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q944N1", "organism_name": "Tomato", "protein_name": "Chromo domain protein LHP1", "length": 399, "firstPublicDate": "2006-07-25", "FUNCTION": "Structural component of heterochromatin involved in gene repression, Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKEGKRKSSRLQSEAAGAGSSRKLDLDGVAAERQERNGYPEDAGSKCEEEPVAGEGEGEGEEKDEAPEVVRVEKGDGDGVAKKVKPKLAEGFYEIETVRRRRTVKGKVYYLIKWRGWPESANTWEPETNLSSCTDIIDAYEESLKSGKLRRRKRKFGATQTHPMIKQQRRFSAPVATYNGPAVKVRIIEEPTPSPPLNVLKATDLVDSNGSELNSKVDEVVNGNGLRLREQNELNLKLSELKGATSTNGNPVDISGNGLTNGFPKVNGAEFYQSDRCTGAKKRKSGCVRRFKRETTSAVKDDTQDALAGGPLATFMQDGSHNHVMVADDSKDGYTITQLVNPVSYKASFSNDMLDVSVTFVAKRADGNLVLVDNKFLKMNNPLLLINFYEENMRYHPTE", "length": 399, "molWeight": 44098, "crc64": "F8C3980FF4DB998B", "md5": "B225F57C3B5D2BEB1BEA09DA709D5030"}}
{"primaryAccession": "Q94A68", "text": "This is Uncharacterized oxidoreductase At1g06690, chloroplastic protein, from Mouse-ear cress, contains 377 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94A68", "organism_name": "Mouse-ear cress", "protein_name": "Uncharacterized oxidoreductase At1g06690, chloroplastic", "length": 377, "firstPublicDate": "2007-05-15", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the aldo/keto reductase family, Aldo/keto reductase 2 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAMATHFTFPFNYVVSEGSHGRRSFVRKLVRAVASGDSVAPAISEESKVKLGGSDLKVTKLGIGVWSWGDNSYWNDFQWDDRKLKAAKGAFDTSLDNGIDFFDTAEVYGSKFSLGAISSETLLGRFIRERKERYPGAEVSVATKFAALPWRFGRESVVTALKDSLSRLELSSVDLYQLHWPGLWGNEGYLDGLGDAVEQGLVKAVGVSNYSEKRLRDAYERLKKRGIPLASNQVNYSLIYRAPEQTGVKAACDELGVTLIAYSPIAQGALTGKYTPENPPSGPRGRIYTREFLTKLQPLLNRIKQIGENYSKTPTQIALNWLVAQGNVIPIPGAKNAEQAKEFAGAIGWSLTDNEVSELRSLASEIKPVVGFPVEYL", "length": 377, "molWeight": 41497, "crc64": "AEC70C10A6B387C9", "md5": "9B4A77A372B3B8F762CA66E79EAB903D"}}
{"primaryAccession": "Q94CG5", "text": "This is Kinase-interacting protein 1 protein, from Violet-flowered petunia, contains 974 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94CG5", "organism_name": "Violet-flowered petunia", "protein_name": "Kinase-interacting protein 1", "length": 974, "firstPublicDate": "2015-02-04", "FUNCTION": "Probably involved in the receptor-like kinase-mediated signal transduction pathway", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLQRAASNAYSWWAASHIRTKQSKWLEQSLHDMQGRVESVIKLIEEDGDSFAKRAEMYYKKRPELINFVEESYRAYRALAERYDHLSKELQTANNTIATIFPEQIQLAMDEEDEYGAPKMPKDFLQMPASGSNIPKVPPKAPIKDLKGLMSTASKQKQGKQSSKIEDAAKSGLSKNEAIEEIDKLQKDILALQTMKEFIRSSYQSSLEKFRGLENQIMEKQQKICELEDEFGEGRVIEDAEACTLMAEAALQSCQETVTQLQEKQESYTQEAREEFKKIEDACNKLNSFRHKYLGDQIDEAKVYISPIQEVDKEIESLQEKIKDQIDATSKGSLTMSQLAEKIDELVNKVVSLETAVSSQTLLLERFRAEADELQAQVQTLEDDKAALTDTHNLNIRVTAIEAKLQNIENLNKDVVNQNSCLRTHFVEARANIDHLSDKLSSVQPDEEIDGTDSSPDQVIALAEIKLEEESLKQKDHPSSAEGLKNLSTIKAEGPKNLSTIKTEGPKSLSTIKAEGPKNLSTIKAEGPKNLSTIKTEGPKSLSTIETEVPKNLSTIKTEDKEVRKQQGSSTVVSDKKTTMKHVTFAQPTPAEKGDEKVSAQSGNTSVYETHTQKSAEKDDELNWQQMLLSGLDDKENILLNEYTAILKNYKEVTKKLSDIEKKDRDTEFELTLQTRELKSAIAKRDEEIHNLRQKLSLMQQGNASENKALKEELLDPSDPSSARGLKPEDLPQIKDGDDEEDVKTILVDQRATVSPLEGKLRMSIDAILDENLDFWLRFSSAFHQIQKFKTTVHDLQNEISKARDKEMQGNSPRVDVKSEIRPLYKHMKEIQNELTVWLEQTLSLKDELERRFSALCSIQEEISKGLKEEVEDETTFSSHQAAKFQGEVLNMKHENKKVREELEAGISRVTILQEDVEKTVTQLDQEFGLTGNQSQLMQSVSKSRIPLQSFIFGTKPKKEKRSLFSRMNPNRKF", "length": 974, "molWeight": 110425, "crc64": "25043EBD5998CBEF", "md5": "5A60FD072BAB997E85CD4FCEFCA52D21"}}
{"primaryAccession": "Q95J56", "text": "This is DnaJ homolog subfamily C member 14 protein, from Bovine, contains 699 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q95J56", "organism_name": "Bovine", "protein_name": "DnaJ homolog subfamily C member 14", "length": 699, "firstPublicDate": "2006-07-25", "FUNCTION": "Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface (By similarity), Promotes cleavage of pestivirus polyprotein", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAQKHPGEGGLCGAHHSGGASLRTLGPSVDPDILSFSGLRDSAGSAPNGTRCLTEHSSPKYTQPPNPAHWSDPSHGPPRGPGPPLAEEDPDQSEASSEESGVDQELSRENETGYQDDGNSSFLSIPSTCNCQGTPGIPEGPYSEGRDSSSSNFCHHCTSPALGEDEELEGEYDEEEPLKFPSDVSRVPSEKKPAPRRQRHRVPAKEDTREGGRRDPRSPGRHRLGRKRSQADKRRGLGLWGAEELCQLGQAGFWWLIELLVLVGEYVETCGHLIYACRQLKGSDLDLLRVWVGVWAGRLRGWAQVMFQFLSQGFCYGAGLFTRFLRLVGALLLLALALLLGCLQLGWRFLVGLSDRLGWRDKATWIFSWLASPTWQRCLILLRESRPWQQLVRIVQWGWLELPWVKQRTNRQANAPVAGGRYCQPEEEVARLLTMAGVPEDELNPFHVLGVEATASDVELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNPERRKEYEMKRMAENELSRSVNEFLSKLQEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFGSRMPGTSGRQRATPDAPPADLQDFLSRIFQVPPGQMSNGNFFAAPQPGPGATAASKPNSTVPKGEAKPKRRKKVRRPFQR", "length": 699, "molWeight": 78178, "crc64": "370F62297595F516", "md5": "FD35093207B848B5CE1BBB665270F8C3"}}
{"primaryAccession": "Q96WW4", "text": "This is Phospholipid-transporting ATPase accessory subunit ivn1 protein, from Fission yeast, contains 371 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q96WW4", "organism_name": "Fission yeast", "protein_name": "Phospholipid-transporting ATPase accessory subunit ivn1", "length": 371, "firstPublicDate": "2008-02-05", "FUNCTION": "Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the lumenal to the cytosolic leaflet of membranes and ensures the maintenance of asymmetric distribution of phospholipids", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the CDC50/LEM3 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSQTEIVKKPKHKRFKRPDKSRFVQQTLPAWQFIFTPWTVLPLLFLLGIVFAPLGAGMFVASRRVKELRIDYTDCMNIGDEFKQVPSTNIEFQYKNVKNVTAMWKSSGDVCTLRFQIPEEMTSPVFAFYRLKNFYQNHRRYTVSADMFQLLGEARTVAQLKSYGFCKPLEANEEGKPYYPCGIIANSLFNDSYSSLLRYESFDSSNSLGLYNMTTNGTAWPEDRERYKKTKYNASQIVPPPNWAKMFPNGYTDDNIPDVSTWDAFQIWMRAAALPTFSKLALRNVTTALQPGIYEMNITYNFPVTEYKGTKTIMFSTTSVIGGKNYFLGILYFVIGGLCAASGVILSIACLIKPRRVGDPRYLSWNRGKSS", "length": 371, "molWeight": 42421, "crc64": "E1C2D56A1A72CDE5", "md5": "401D61192E0DBED5E6F7B2F5BA8F6E35"}}
{"primaryAccession": "Q99158", "text": "This is Nucleotide exchange factor SIL1 protein, from Yeast, contains 426 amino acids, is soluble, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99158", "organism_name": "Yeast", "protein_name": "Nucleotide exchange factor SIL1", "length": 426, "firstPublicDate": "1997-11-01", "FUNCTION": "Required for protein translocation and folding in the endoplasmic reticulum (ER), Probably functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2, It is not required for viability but is essential for optimal growth at elevated temperatures", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the SIL1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFSKTLLLALVAGALAKGEDEICRVEKNSGKEICYPKVFVPTEEWQVVWPDQVIPAGLHVRMDYENGVKEAKINDPNEEVEGVAVAVGEEVPEGEVVIEDLTEENGDEGISANEKVQRAIEKAIKEKRIKEGHKPNPNIPESDHQTFSDAVAALRDYKVNGQAAMLPIALSQLEELSHEIDFGIALSDVDPLNALLQILEDAKVDVESKIMAARTIGASLRNNPHALDKVINSKVDLVKSLLDDLAQSSKEKADKLSSSLVYALSAVLKTPETVTRFVDLHGGDTLRQLYETGSDDVKGRVSTLIEDVLATPDLHNDFSSITGAVKKRSANWWEDELKEWSGVFQRSLPSKLSSKVKSKVYTSLAAIRRNFRESVDVSEEFLEWLDHPKKAAAEIGDDLVKLIKQDRGELWGNAKARKYDARDEL", "length": 426, "molWeight": 47174, "crc64": "EB475653FF712BF1", "md5": "822B4548F3002CC9A7A45070A32A200C"}}
{"primaryAccession": "Q99177", "text": "This is Pre-mRNA-splicing factor BRR1 protein, from Baker's yeast, contains 341 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99177", "organism_name": "Baker's yeast", "protein_name": "Pre-mRNA-splicing factor BRR1", "length": 341, "firstPublicDate": "2006-06-13", "FUNCTION": "Involved in mRNA splicing, Required for snRNA accumulation and manufacture of snRNPs", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the BRR1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKRGESQAPDAIFGQSRAFALSDSSVNPDVIEYLKSVRQEALRTNAISIKNHMNLQKRTRHKSSMYDDEDEGALKRHAISPSLIRLQRNVEIWVRWFNSVKATVLTNAYEFTGYEDETLDLLLLFLKNYLEDMPSKCTTVEKIISVLNQHSFPEKAEEKEENLQIDEEWAKNILVRLEKTKIDSVEDVKKVITEGDKHELVGYNQWFQYLINNEPQHTTFHEKITSKQLWVLIKYMSNTWIKEIHKKGRHYRRLQDWLFYILVHTPERVTAEYTSILRDLGKKCLELIQKKPVEAHENKITLPKEMAELNVEIPAAVENMTITELTVSVIAVNYGQKDLIE", "length": 341, "molWeight": 39860, "crc64": "BFAE093567405283", "md5": "56CC31276CACCC6C32F31EDC6AD5149B"}}
{"primaryAccession": "Q99JS0", "text": "This is Noncompact myelin-associated protein protein, from Mouse, contains 100 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99JS0", "organism_name": "Mouse", "protein_name": "Noncompact myelin-associated protein", "length": 100, "firstPublicDate": "2006-12-12", "FUNCTION": "Plays a role in myelin formation", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTTATTLGDAVFSLNMTRGEDALYKSSGAIVAAIVVVVIIIVTLVLILLKMYNRRMRTRRELEPKSPKPPVPPALDPSSNGSQQPATVTFDPANVHVETR", "length": 100, "molWeight": 10846, "crc64": "6A30789C5C0368D0", "md5": "1AC21870CDB4CA4D7E038B013AF89857"}}
{"primaryAccession": "Q99MG7", "text": "This is Female-specific lacrimal gland protein protein, from Golden hamster, contains 172 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99MG7", "organism_name": "Golden hamster", "protein_name": "Female-specific lacrimal gland protein", "length": 172, "firstPublicDate": "2015-06-24", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the calycin superfamily, Lipocalin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MVKFLLLALALGVSCAHYQNLEVSPSEVDGKWYSLYIAADNKEKVSEGGPLRAYIKNVECIDECQTLKITFYTKVEGVCQEHTIVGRKGEDGKYITDFSGQNYFHIVEKSDDTMTFHNVNVDDSGKTNVILVVGRGESSSIEQKQRFEKTAEEYDIPKENIEDLVPTDNCDQ", "length": 172, "molWeight": 19369, "crc64": "F2E29E87B831F629", "md5": "064CFF55254C1FF988BD3628B6787B7A"}}
{"primaryAccession": "Q99ML4", "text": "This is Divergent protein kinase domain 1B protein, from Mouse, contains 431 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99ML4", "organism_name": "Mouse", "protein_name": "Divergent protein kinase domain 1B", "length": 431, "firstPublicDate": "2007-05-15", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DIPK family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRRLRRLVHLVLLCPFSKGLQGRLPGLRVKYVLLVWLGIFVGSWMVYVHYSSYSELCRGHVCQVVICDQYRKGIISGSVCQDLCELQKVEWRTCLSSAPGQQVYSGLWQDKEVTIKCGIEEALNSKAWPDAAPRRELVLFDKPTRGTSIKEFREMTLSFLKANLGDLPSLPALVDQILLMADFNKDSRVSLAEAKSVWALLQRNEFLLLLSLQEKEHASRLLGYCGDLYLTEGIPHGSWHGAVLLPALRPLLPSVLHRALQQWFGPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEATVRRFLQGRHCEQSSDCIYGRDCRAPCDRLMRQCKGDLIQPNLAKVCELLRDYLLPGAPAGLYEELGKQLRTCTTLSGLASQIEAHHSLVLSHLKTLLWREISNTNYS", "length": 431, "molWeight": 48792, "crc64": "A4F84CD9CDC33202", "md5": "66D56EE105F070B00A5C1E9B6DE5A5DC"}}
{"primaryAccession": "Q99MU0", "text": "This is Protein DBF4 homolog A protein, from Chinese hamster, contains 676 amino acids, has 1 DBF4-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [289, 337], "description": "DBF4-type", "keyword_description": "Zinc finger", "textural_description": "DBF4-type Zinc finger"}], "meta_data": {"primaryAccession": "Q99MU0", "organism_name": "Chinese hamster", "protein_name": "Protein DBF4 homolog A", "length": 676, "firstPublicDate": "2006-05-02", "FUNCTION": "Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation, Required for progression of S phase, The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"DBF4-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEKSKCKPLWEKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLVSNKKEAKYAQTLGQVSPVPSPESAYTAETTSPHPSHDGSSFKSPDRVCLSRGKLLAEKAVKDHDFIPANSILSNALTWGVKILHIDDIRYYIEQKKKELCSLKKSSTSVRDSGKKAGTTIQKARTGRLKKPFLKVEDVNRSYRPFYLQLTSVPSINYATHKPCSPFDIEKPSSVQKQAQPKPRPNTDGDKCGGTPVQLQLKEKRKKGYCECCLQKYEDLETHLLSEKHKNFAQSNQYQVVDDIVSKLVFDFVEYERDTPKKKRIKYSVGSFSSVSANVLKNTEPKEKLQLEPIFQKDMVESNGQLPEEIFQCEDIQCEDIQKPEQRLVLASEPMSYSSTGLKGRDEKAASMLNASEPDIKQKFTQLPPCKNEQEGILDVSEHKLIINRNDLEQRVGDSVGVPRSCVQVSHLSPENSLPQPKLTADTTHFSAKDLQEKDLHFVFGHDSDLVTLNTSKEQLTVKAGTPSCGPQQPNECDTENTDNLPCGKIQRKVRLLLGQKKKNVDPSAELDKKRTEFLPMCEDRTCGSPVQSLLDLFQTSGEKSDFLGFTSYTENSGLCDVLDVWEDENSSSLLSTFFSSPSASTFIGF", "length": 676, "molWeight": 75850, "crc64": "EC7EEBDD80D40B8C", "md5": "A40222B1F0444641EABC09EF85B62F53"}}
{"primaryAccession": "Q9C0U6", "text": "This is Xylulose kinase protein, from Fission yeast, contains 555 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C0U6", "organism_name": "Fission yeast", "protein_name": "Xylulose kinase", "length": 555, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the FGGY kinase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFLGLDLSTQQLKGVVIDESLNVHQEVAVDFDRDLSDYNTIKGVYRNGYEVFAPVCMWLDAIDLLFERLKASVDVSKIQAISGAGQQHASVFLLKGSKKALNSLDAKSSLKQQLESLIHPTSPNWQDASTTKECEELESCIGGAKALADLTGSKAHLRFTGPQIKRFRRLHPETYENTERIALVSNFLASVLLQTEAPLDISDVCGMNLWDIQNEKFDIRLLEEVAGNSKGPDLANKLGTVEINGAKHLGPIGKYFVKKYGFSPNCQIIPLTGDNPATILSLPLRPGKDVLLSLGTSTTALMATQNYVCSPEYHMFAHPVTQNHYMVMLCYKNGSLAREQVRNTINEKYNVSDNTSWDRFNESILNPNIKGAGEKKQLGLFYPQREILPAVGPGTWRFAIQGTELYQVDKDEESWDYPDEDASAIVESQNLDIRMRITPLLTGIPQPDRVYVVGGASRNEAIVFKISQVLGCDVYRLKHGGSNACAVGGAIKAAYAMNGKGFTFEEYVNKSWDESKKIELIMNKPSAQTYEEYGKLLPFLKKAEDIAIQQSDIRH", "length": 555, "molWeight": 61683, "crc64": "610CE6A309244E01", "md5": "BA59684DCE14F58585019093E888BF71"}}
{"primaryAccession": "Q9CA19", "text": "This is Small ribosomal subunit protein uS13m protein, from Mouse-ear cress, contains 154 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CA19", "organism_name": "Mouse-ear cress", "protein_name": "Small ribosomal subunit protein uS13m", "length": 154, "firstPublicDate": "2003-06-27", "FUNCTION": "Located at the top of the head of the small subunit, it contacts several helices of the 18S rRNA", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uS13 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLGLRRSATTLFDISQSLLRNVTFHGLRVQGIRVGNAEVPNNKPLKTGLQEVYGIGRRKSHQVLCHLGITNKLARDLTGKELIDLREEVGQHQHGDELRRRVGSEIQRLVEVDCYRGSRHRHGLPCRGQRTSTNARTKKGKAVAIAGKKKAPRK", "length": 154, "molWeight": 17272, "crc64": "923C9C316D842059", "md5": "4620660B2809485B80A56E9153E16BF4"}}
{"primaryAccession": "Q9CQL4", "text": "This is Large ribosomal subunit protein bL20m protein, from Mouse, contains 149 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9CQL4", "organism_name": "Mouse", "protein_name": "Large ribosomal subunit protein bL20m", "length": 149, "firstPublicDate": "2006-09-05", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL20 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVFLTTRLWLRNRLTDRYWRVQEVLKHAQHFRGRKNRCYRLAVRAVTRAFVKCTKARRLKKRNLRTLWINRITAASQEHGLKYPAFIVNLIKCQVELNRKVLVDLAIYEPKTFKSLAALAKRRQQEGFAAALGDGKEPEGIFSRVVQYH", "length": 149, "molWeight": 17595, "crc64": "7B86D8C568B633AE", "md5": "E823799747A4D16BEBC37DF8D4CE1653"}}
{"primaryAccession": "Q9D563", "text": "This is Transmembrane protein 114 protein, from Mouse, contains 222 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9D563", "organism_name": "Mouse", "protein_name": "Transmembrane protein 114", "length": 222, "firstPublicDate": "2008-10-14", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRVRLGALAGAAALSGALSFVLLAAAIGTDFWYIIDTERLERSSQRMRDQGPANRSQQEPLSSHSGLWRTCRVQSSCTPLMNPFWQENVTVSDSSRQLLTMHGTFVILLPLSLIVMVFGGMTGFLSFLLRAHLLLLLTGILFLFGAMVTLTGISIYIAYSAVAFREAVCLLEERALLDQVDIRFGWSLALGWISFVSELLTGVVFLAAARALSLSQRQDQAI", "length": 222, "molWeight": 24388, "crc64": "8AB6E66C94ECAD52", "md5": "A2DFAD0F84D82A6E03479A34E1C8F802"}}
{"primaryAccession": "Q9ERZ0", "text": "This is Hemogen protein, from Mouse, contains 503 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ERZ0", "organism_name": "Mouse", "protein_name": "Hemogen", "length": 503, "firstPublicDate": "2006-07-11", "FUNCTION": "Regulates the proliferation and differentiation of hematopoietic cells, Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model, May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB) (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDMGKGRPRLKLPQMPEAHPQKSCAPDIIGSWSLRNREQLRKRKAEAQGRQTSQWLLGEQKKRKYQRTGKGNKRGRKRQGNVEQKAEPWSQTERERVQEVLVSAEEETEHPGNSATEALPLVPSPTKAVPADQCSEAHQESIQCQERAIQNHSQTHLSPTTCQGIAVLQHSPKMCQDMAEPEVFSPNMCQETAVPQTYPPKALEEMAAAEPLSPKMCQETTVSPNHSSKVPQDMAGPEALSPNMCQEPTVPQEHTLKMCHDVARPEVLSPKTHQEMAVPKAFPCVTPGDAAGLEGCAPKALPQSDVAEGCPLDTTPTSVTPEQTTSDPDLGMAVTEGFFSEARECTVSEGVSTKTHQEAVEPEFISHETYKEFTVPIVSSQKTIQESPEPEQYSPETCQPIPGPENYSLETCHEMSGPEDLSIKTCQDREEPKHSLPEGAQKVGGAQGQDADAQDSENAGAFSQDFTEMEEENKADQDPEAPASPQGSQETCPENGIYSSALF", "length": 503, "molWeight": 55043, "crc64": "B1027B81B55BB08D", "md5": "1E6DB44C3AE627E7E0533F91FDCDBA9F"}}
{"primaryAccession": "Q9FG36", "text": "This is Thioredoxin-like 3-1, chloroplastic protein, from Mouse-ear cress, contains 210 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FG36", "organism_name": "Mouse-ear cress", "protein_name": "Thioredoxin-like 3-1, chloroplastic", "length": 210, "firstPublicDate": "2004-08-31", "FUNCTION": "Probable thiol-disulfide oxidoreductase that may participate in various redox reactions", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the thioredoxin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFENLKISRHISSSTKNLLKAKKIMAALASNPQMLTRQAHGNKKEQLWRKESLNLEKKCGFCVSVYSNEKLGRSHMEKEWRLKAFWSNIAQPTTLEMEPINNVEELDAVLSHARQLSQPIIIEWMASWCRKCIYLKPKLEKLAAEYNNRAKFYYVDVNKVPQTLVKRGNISKMPTIQLWKEDEMKEEVIGGHKGWLVIEEVRELINKFV", "length": 210, "molWeight": 24517, "crc64": "7A73465BE81EF47D", "md5": "27C432F70AADCEB225827D05F0CD5F15"}}
{"primaryAccession": "Q9FK07", "text": "This is CLP protease regulatory subunit CLPX1, mitochondrial protein, from Mouse-ear cress, contains 579 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FK07", "organism_name": "Mouse-ear cress", "protein_name": "CLP protease regulatory subunit CLPX1, mitochondrial", "length": 579, "firstPublicDate": "2015-10-14", "FUNCTION": "ATP-dependent specificity component of the mitochondrial Clp protease (PubMed:11352464), It directs the protease to specific substrates (By similarity), Can perform chaperone functions in the absence of ClpP (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the ClpX chaperone family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAALRSNTSRETASLTLSHFRYFIFNRIHTARTATSPPHCNHRSKSDEKFPYKISSLGTSFLDNRGGGERRNSTKCYAAQKKLSGVGSSVVILSSQGDPPDLWQPPGDGVSVRVNGSSVNLGRGGGGGGSSPGGPGNGTGSNSKEDCWGGSNLGSDFPTPKEICKGLNKFVIGQERAKKVLSVAVYNHYKRIYHESSQKRSAGETDSTAAKPADDDMVELEKSNILLMGPTGSGKTLLAKTLARFVNVPFVIADATTLTQAGYVGEDVESILYKLLTVADYNVAAAQQGIVYIDEVDKITKKAESLNISRDVSGEGVQQALLKMLEGTIVNVPEKGARKHPRGDNIQIDTKDILFICGGAFVDIEKTISERRHDSSIGFGAPVRANMRAGGVTNAAVASNLMETVESSDLIAYGLIPEFVGRFPVLVSLSALTENQLMQVLTEPKNALGKQYKKMYQMNSVKLHFTESALRLIARKAITKNTGARGLRALLESILMDSMYEIPDEGTGSDMIEAVVVDEEAVEGEGRRGSGAKILRGKGALARYLSETNSKDSPQTTKEGSDGETEVEAEIPSVVASM", "length": 579, "molWeight": 61964, "crc64": "AF8CF9E9217AE7FB", "md5": "C3866C31FAF61E073A1DAD7B07DB7661"}}
{"primaryAccession": "Q9FL03", "text": "This is Scarecrow-like protein 4 protein, from Mouse-ear cress, contains 584 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FL03", "organism_name": "Mouse-ear cress", "protein_name": "Scarecrow-like protein 4", "length": 584, "firstPublicDate": "2008-09-23", "FUNCTION": "Probable transcription factor involved in plant development", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the GRAS family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAYMCTDSGNLMAIAQQVIKQKQQQEQQQQQHHQDHQIFGINPLSLNPWPNTSLGFGLSGSAFPDPFQVTGGGDSNDPGFPFPNLDHHHATTTGGGFRLSDFGGGTGGGEFESDEWMETLISGGDSVADGPDCDTWHDNPDYVIYGPDPFDTYPSRLSVQPSDLNRVIDTSSPLPPPTLWPPSSPLSIPPLTHESPTKEDPETNDSEDDDFDLEPPLLKAIYDCARISDSDPNEASKTLLQIRESVSELGDPTERVAFYFTEALSNRLSPNSPATSSSSSSTEDLILSYKTLNDACPYSKFAHLTANQAILEATEKSNKIHIVDFGIVQGIQWPALLQALATRTSGKPTQIRVSGIPAPSLGESPEPSLIATGNRLRDFAKVLDLNFDFIPILTPIHLLNGSSFRVDPDEVLAVNFMLQLYKLLDETPTIVDTALRLAKSLNPRVVTLGEYEVSLNRVGFANRVKNALQFYSAVFESLEPNLGRDSEERVRVERELFGRRISGLIGPEKTGIHRERMEEKEQWRVLMENAGFESVKLSNYAVSQAKILLWNYNYSNLYSIVESKPGFISLAWNDLPLLTLSSWR", "length": 584, "molWeight": 64587, "crc64": "C591D3AD03663039", "md5": "B20759A5304BA392CCF007027E09B8A0"}}
{"primaryAccession": "Q9FNJ9", "text": "This is Probable 2-carboxy-D-arabinitol-1-phosphatase protein, from Mouse-ear cress, contains 482 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FNJ9", "organism_name": "Mouse-ear cress", "protein_name": "Probable 2-carboxy-D-arabinitol-1-phosphatase", "length": 482, "firstPublicDate": "2014-10-29", "FUNCTION": "Phosphoglycerate mutase-like protein lacking PGM activity, but having 2-carboxy-D-arabinitol 1-phosphate (CA1P) phosphatase activity, Prevents the accumulation of D-glycero-2,3-pentodiulose-1,5-bisphosphate (PDBP) a potent inhibitor of ribulose-1,5-bisphosphate carboxylase (RuBisCO), PDBP is produced during the oxidation of ribulose-1,5-bisphosphate, the substrate of RuBisCO", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the phosphoglycerate mutase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MISLPLTTPILPSRCLLHKTRRQNSTRRRLLIRSSSSLQDQFTVETTKRVVLVRHGQSTWNEEGRIQGSSDFSVLTKKGESQAEISRQMLIDDSFDVCFTSPLKRSKKTAEIIWGSRESEMIFDYDLREIDLYSFQGLLKKEGKEKFGEAFKQWQEDPANFIIDGHYPVRELWSRARSCWPGILAHESKSVLVVAHNAVNQALLATAIGLGTEYFRSLLQSNCGVSVLDFIPRADGGSPHVCLNRLNQTPNSPLAGGSSGGRKASKQIILVCHGQGNNEDSAVINQAANNDQAMNMLGVIHSQKTAELLLDLRVSSIVCSPKTASIESSGVISRVQEAAGCLGVDNVPHYVKTKQMNELDVESVLRKSNKDNDVIASQLDEEAFSALWNRSEKAWESLLDELSDEKSNPGEIMVVVGPAMTHISLIAQCLNLTKEALGLFHLDAGSISVIDFPDGPSSKGVIRCTNYTAHLGRWSIPITKPA", "length": 482, "molWeight": 53114, "crc64": "3EA8C450B12D2B51", "md5": "CF5096460832F872F388E42E2955881A"}}
{"primaryAccession": "Q9GL25", "text": "This is Epididymal sperm-binding protein 1 protein, from Dog, contains 245 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9GL25", "organism_name": "Dog", "protein_name": "Epididymal sperm-binding protein 1", "length": 245, "firstPublicDate": "2007-10-23", "FUNCTION": "Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation, Has phosphorylcholine-binding activity (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the seminal plasma protein family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNPWSSYLLGWTTFLLYFYETSGKIPNLSSLGKHEFTKPWISIKEDQKDSCVFPFVYKGSSYFSCIKTNSFSPWCATRAVYNGQWKFCMADDYPRCIFPFIFRGKSHNSCITEGSFLRRLWCSVTSSFDENQQWKYCETNEYGGNSFSKPCIFPSIFRNSTIFECMEDENNKLWCPTTENMDEDGKWSLCADTRISSLVPGFPCHFPFSYKNKNYYNCIGKGTKENLTWCATSYNYDRDHTWVYC", "length": 245, "molWeight": 28746, "crc64": "DBDF6A6B540D5010", "md5": "D433CBC2F14E7FEBD3AC1C2C48258786"}}
{"primaryAccession": "Q9GMC9", "text": "This is Translocator protein protein, from Sheep, contains 169 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9GMC9", "organism_name": "Sheep", "protein_name": "Translocator protein", "length": 169, "firstPublicDate": "2008-04-29", "FUNCTION": "Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial, It is apparently not required for steroid hormone biosynthesis, Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity), Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:11145616)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the TspO/BZRP family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAPPWVPAVGFTLVPSPGGFLGTQYIRGEGFRWYASLQKPPWHPPRWILAPIWGTLYSAMGYGSYLIWKELGGFSKEAVVPLGLYAGQLALNWAWPPLFFGARQMGWAFVDLLLTGGMAAATAMAWRQVSPPAACLLYPYLAWLAFAAMLNYRMWQDNQGRRSGRRLSE", "length": 169, "molWeight": 18916, "crc64": "F86FBD9B0149484F", "md5": "863F7C9EC6F4E8879B60A4A61BC313E8"}}
{"primaryAccession": "Q9GPZ7", "text": "This is Mitochondrial division protein fszB protein, from Social amoeba, contains 366 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9GPZ7", "organism_name": "Social amoeba", "protein_name": "Mitochondrial division protein fszB", "length": 366, "firstPublicDate": "2008-04-08", "FUNCTION": "Probably involved in mitochondrion division process, Binds to and hydrolyzes GTP (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the FtsZ family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTILNRFCRTILLTNLELTNCGIRKNNSYKCRSFTHTINIDTNHIVPIHTQSNITLELFQPKISVVGVGGGGGNAVNHMISQSLEGVEFFVCNTDSQDLIKSNSINKIQLGPQLTKGHGAGANPEKGRLAAEESKNKIIQTFKDTDLLFLAAGMGGGTGTGSSPIIAKTIKEFKKETIIVGVVTVPFNFEGKRKEIIAKKGLEELSKYVDTLVVISNQNLLDASKSDIQLEQAFLMVDEILHTGIRSIANIINVPGMINLDYSDVVNILKNRKGLSRIGFGEASGEDRAYKAVHKAIKNPLIEIDDQKFTGLLVNISGGNDITLNEISKTINYLQQNADPDVQVFVGHTVDNSLLGKIRISCLFVH", "length": 366, "molWeight": 39943, "crc64": "3F3351F6C6366987", "md5": "EFE4ED8B71E17DA2B0A98B0A2B397996"}}
{"primaryAccession": "Q9GZP8", "text": "This is Immortalization up-regulated protein protein, from Human, contains 106 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9GZP8", "organism_name": "Human", "protein_name": "Immortalization up-regulated protein", "length": 106, "firstPublicDate": "2003-08-04", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEFDLGAALEPTSQKPGVGAGHGGDPKLSPHKVQGRSEAGAGPGPKQGHHSSSDSSSSSSDSDTDVKSHAAGSKQHESIPGKAKKPKVKKKEKGKKEKGKKKEAPH", "length": 106, "molWeight": 10897, "crc64": "CB0D3F56E1870DAE", "md5": "B2DBE43A6C19B0B89FCFA6C0E54AF5B0"}}
{"primaryAccession": "Q9H1Z4", "text": "This is WD repeat-containing protein 13 protein, from Human, contains 485 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H1Z4", "organism_name": "Human", "protein_name": "WD repeat-containing protein 13", "length": 485, "firstPublicDate": "2002-03-27", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQLLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRREQK", "length": 485, "molWeight": 53715, "crc64": "F57D6CA650CEC569", "md5": "94BDE21010BCE2C995D3A169F8AE9DF5"}}
{"primaryAccession": "Q9H425", "text": "This is Uncharacterized protein C1orf198 protein, from Human, contains 327 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H425", "organism_name": "Human", "protein_name": "Uncharacterized protein C1orf198", "length": 327, "firstPublicDate": "2007-03-20", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASMAAAIAASRSAVMSGNRPLDDRERKRFTYFSSLSPMARKIMQDKEKIREKYGPEWARLPPAQQDEIIDRCLVGPRAPAPRDPGDSEELTRFPGLRGPTGQKVVRFGDEDLTWQDEHSAPFSWETKSQMEFSISALSIQEPSNGTAASEPRPLSKASQGSQALKSSQGSRSSSLDALGPTRKEEEASFWKINAERSRGEGPEAEFQSLTPSQIKSMEKGEKVLPPCYRQEPAPKDREAKVERPSTLRQEQRPLPNVSTERERPQPVQAFSSALHEAAPSQLEGKLPSPDVRQDDGEDTLFSEPKFAQVSSSNVVLKTGFDFLDNW", "length": 327, "molWeight": 36346, "crc64": "769AFAB47FE287C4", "md5": "906F4B9FDD236F34294C04906F39792C"}}
{"primaryAccession": "Q9H6A0", "text": "This is DENN domain-containing protein 2D protein, from Human, contains 471 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9H6A0", "organism_name": "Human", "protein_name": "DENN domain-containing protein 2D", "length": 471, "firstPublicDate": "2006-06-27", "FUNCTION": "Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B, Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEGQVVGRVFRLFQRRLLQLRAGPPQDNSGEALKEPERAQEHSLPNFAGGQHFFEYLLVVSLKKKRSEDDYEPIITYQFPKRENLLRGQQEEEERLLKAIPLFCFPDGNEWASLTEYPRETFSFVLTNVDGSRKIGYCRRLLPAGPGPRLPKVYCIISCIGCFGLFSKILDEVEKRHQISMAVIYPFMQGLREAAFPAPGKTVTLKSFIPDSGTEFISLTRPLDSHLEHVDFSSLLHCLSFEQILQIFASAVLERKIIFLAEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRFQQEVMDSPMEEVLLVNLCEGTFLMSVGDEKDILPPKLQDDILDSLGQGINELKTAEQINEHVSGPFVQFFVKIVGHYASYIKREANGQGHFQERSFCKALTSKTNRRFVKKFVKTQLFSLFIQEAEKSKNPPAGYFQQKILEYEEQKKQKKPREKTVK", "length": 471, "molWeight": 53672, "crc64": "E885FA53369C738C", "md5": "7819871435EE5323A6B3AB0498F9F22B"}}
{"primaryAccession": "Q9HDW0", "text": "This is Target of rapamycin complex 1 subunit toc1 protein, from Fission yeast, contains 430 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HDW0", "organism_name": "Fission yeast", "protein_name": "Target of rapamycin complex 1 subunit toc1", "length": 430, "firstPublicDate": "2007-09-11", "FUNCTION": "Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals, Tor2 is essential for growth, Nutrient limitation and environmental stress signals cause inactivation of TORC1, Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ribosomal protein gene expression, TORC1 negatively controls G1 cell-cycle arrest, sexual development and amino acid uptake, Represses mating, meiosis and sporulation efficiency by interfering with the functions of the transcription factor ste11 and the meiosis-promoting RNA-binding protein mei2", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQLQSPFGDGISCECLNIRVLGIPNETKHQWIFVPRDLIKIKIYSLLQICKAENCSAVACRGCNLCILAVQGNIEISEEPQKLFQEENVKVYIYDSAISLSSVRASFPISELGIRMDIIKARAEPREDEIRASFSSLVNKEIKRTVEELLLSKRSTNRLSLLAFMRNQQLNYEAYETKLLEDASTIEKSLEKEVKTIYDSNIASPKESSDAIDADHAMIDESRSTQRRKSKPKKHVAFTDEYQVAFSDKPGKYFNQPMQYSKQFKLDNPDYEASSDSLNDIENLSTLTFRSDEELEFDFDTNNINNNKSGDSLEMSTTIPSDEENEDFTSKVDAMEIHSGSLPLNIDSSPIFTNHSPSSSLSSESSFEASPSSFVDRKNRWIQMLKKADEHSRSIQARSMGYVLSDDLDNSKAFRPYKQSFLAQGWKSLN", "length": 430, "molWeight": 48792, "crc64": "F1EE640B81904606", "md5": "438BFC79C9657DD76EF53E347E43F70D"}}
{"primaryAccession": "Q9HDX9", "text": "This is Glutamate--tRNA ligase, mitochondrial protein, from Fission yeast, contains 526 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HDX9", "organism_name": "Fission yeast", "protein_name": "Glutamate--tRNA ligase, mitochondrial", "length": 526, "firstPublicDate": "2008-01-15", "FUNCTION": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the class-I aminoacyl-tRNA synthetase family, Glutamate--tRNA ligase type 1 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLSYTSCAKLICSRYIVSKISFYSLKRCNSTAVVRTRFAPSPTGFLHLGSLRTALFNYLWAKKSNGKFILRLEDTDQKRKVTGSDLEIYKVLKQFNLQWDEGPIVGGPYGPYEQSSRLQIYQKYAQHLIETGRAYVSYSVPIATTKIDSSTKYHEISIDDLTDAQRKLYKSKKFPYVVRFRMKEPSPFTDLVYGKIAIKSDSREIEESNNFVILKSDGFPTYHFANVVDDHLMHITHVIRGEEWVPSTIKHIQLYEAFGWKPPKFAHLPLLVNPDGSKLSKRQNDAHVSSLLQEGFLPEAILNFIALMGWSSRQKSDFLPMKELIDLFSIDKLTKSSSIVAFEKLYFLNKNYLRRAISDVNRLDELIELVQPRLIQKFSHSSRSHDKSYTKKLLLLLKNKVHTIKEFEKIVFYFYEASDLQQIRSLVSSLITVEELPKILTTILNKFETIEWNTHEIQISLKEIAMEHQMPLKKIQSLLRYGLCGNLPGGGISDTISLLGKETVKSRLERLLLSLKHELPKRSCIV", "length": 526, "molWeight": 60645, "crc64": "F8F34F510B43A2F4", "md5": "33238C5C82FDC708804E0A99DD07D424"}}
{"primaryAccession": "Q9HE09", "text": "This is Putative ATP-dependent DNA helicase fml2 protein, from Fission yeast, contains 783 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HE09", "organism_name": "Fission yeast", "protein_name": "Putative ATP-dependent DNA helicase fml2", "length": 783, "firstPublicDate": "2008-09-23", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the DEAD box helicase family, DEAH subfamily, FANCM sub-subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIVLRDSSDYSDSEVDLPSIEVNGERGNVPTSVLCNVEGSLLNSNPALRQPNLKCIKHNQDVENTTFQLDLRGCRVPSSQPQVITELENNIDIPKNIDAMQNWIFPQTQQYRNYQKEFCEQALFHNLLLALPTGLGKTFIAAVVMLNYFRWFPESKIIFLAPTKPLLLQQRVACSNVAGMSPGATAELNGEVSPDRRLFEYNTKRVFFMTPQTLQNDLKEHLLDAKSIICLIFDEAHRATGNHSYAQVMRAVLRSNSHFRVLGLTATPGSSTASVQKVVDCLHISKLIVRNEESIDIRSYVFHKKIQLIKVTISSEMNILKSDFANLYRPYFNFLRQKKLIPINCECLNIKAYTLFVSLRKYSFSSKNVQSKEKSKIMSCFTLLISCAHITYLLDCHGIIQFYQKLVETKNKAEGKGSGQSFWLFTSKPFAFYLEHLHNKIQGLSLNHPKMNHLLELLKEHFKDTSEGYQNQRVMIFTEFRNTAEYITTTLLAIRPMVRASLFIGQANSAYSTGMNQMQQKETIDQFRAGVINTLVATSIGEEGLDIGDTDMIICYDASSSPIRTIQRMGRTGRKKSGKVFVLLTEDCEDSKWERSQVSYRRVQKVIESGKKIALKKDVPRLIPSNIQPIFKFQALQNNADATLILNSYNNNSSSLSPVNTLANQAHSRSKRYLPFIVDDVFEDMESNLRVPTEDAKIKRFKSDYRSCIYNARRNVFSKPTYMGDKLTKFAKVPHSLLTLSIYRRGRLLQQCSPSSVTKYLKYEEKFKRKRMKKTSNALFQST", "length": 783, "molWeight": 89463, "crc64": "CD096AE05D9F0263", "md5": "35170BB26CD0717E21C0255D9C6AA71A"}}
{"primaryAccession": "Q9HEM6", "text": "This is Guanosine-diphosphatase protein, from Yeast, contains 522 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HEM6", "organism_name": "Yeast", "protein_name": "Guanosine-diphosphatase", "length": 522, "firstPublicDate": "2004-04-13", "FUNCTION": "After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the GDA1/CD39 NTPase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MHINSVVRNYRFLIGALTALMLLLLLRSSASPQVGSLANSNKVDTPDGLKVPGASSPISQNINEDSQKQTAKDHTSQNLESGSNSLSKSQCTEGHKYVVMIDAGSTGSRVHVYEFDVCTQPPTLINETFEMLKPGLSSFDIDAVGAAKSLDPLLKIAMDAVPKDKRNCTPVAVKATAGLRMLGDEKSSKILAQVRKHLEQDYPFPVVDGDGVSIMDGEEEGVYAWVTANYLLGNIGAGSKLPTAAVFDLGGGSTQIVFEPSFPPNEKMVDGEHKYELSFGGHDYTLYQFSHLGYGLMQGRNKINTELVNVAISSGTITKGQTARTYELSSPCLPPGTTAEGEKVKISDDEIYTVNFKGPKVPAGPQCRYLADKILNKDAKCNTPPCSFNGIHQPSLVHTFKETSDLYVFSYFYDRTQPLGLPLSFTLQELQDLARTVCNGEEVWESVFSGIEGSLSELSKEPQWCLDLNFQVSLLHTGYDIPLQRELRTAKTIANNELGWCLGASLPLLESANWSCKVSKVE", "length": 522, "molWeight": 56863, "crc64": "A7A27902607A6732", "md5": "741D0F3FD0C5B53BEE29F7AB0C13131D"}}
{"primaryAccession": "Q9HFP8", "text": "This is Cell wall mannoprotein 1 protein, from Neosartorya fumigata, contains 284 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HFP8", "organism_name": "Neosartorya fumigata", "protein_name": "Cell wall mannoprotein 1", "length": 284, "firstPublicDate": "2015-04-29", "FUNCTION": "Constitutive protein of the cell wall, Antigen target of host humoral immune response", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the cell wall mannoprotein 1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRFSALLVTLGLTGALATPTLVSREAPAVGVISDISAQTSALASAVSSYNGGDPSAVKSASEKLVSTINSGVDTVKSGPALSTADALALTSPVQDLTKQVEGVIDDLISKKDKFVAANAGGTVYEDLKAQYTAADSLAKAISAKVPESLSDIAAQLSAGITAAIQKGIDAYKDAASSTGTASSSAPATETATATETSTATGTVTETATSTPVIPTGTASGSASATPSTTATPTTGGSGSGSGSSTGTATASTSTNLLSTGAASKEHFSYSLGGAVVAAAIAVAL", "length": 284, "molWeight": 27361, "crc64": "39FEB2B5DB5345E2", "md5": "56B2EB56B93ABFA4B2ABC9D5B31B50A0"}}
{"primaryAccession": "Q9HG09", "text": "This is Peroxisomal membrane protein PEX14 protein, from Yeast, contains 425 amino acids, is membrane-bound, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HG09", "organism_name": "Yeast", "protein_name": "Peroxisomal membrane protein PEX14", "length": 425, "firstPublicDate": "2005-03-29", "FUNCTION": "Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 or PEX20 receptors (PubMed:11329173), The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity), Mechanistically, PEX5 (or PEX20) receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (By similarity)", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the peroxin-14 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSIREEMVTSAVEFLKNPQIADSPLAKKIEFIESKGLNEAEVKEALLRSQGGNGSSSVASQVSSYSPSASQSSVAPSPPPFPDHYRNAPPLPERDWKDYFVMATATAGVSFGLYKVISNYVLPKLLPPSKEAIELDKEAIDREFTRVEALLNTFEEDQKAFYEEQREKSGKIEDTLTEIDAIISKTNEKNLNNEESLKYLKLEIESIKNTLMKNIDSQKSTISSELGSIEAQLDELKKLIVAKPEDEPIRAAPQPSLTTGANSLTSESSGRSSIPHSQSVPIRTQLTTPPSDSDTSGPAKLHIPPATSIPSLKDILRKEKNRTVDTFSKSNLGKDLESVAQSDPDKVEKYEGRRDLKSLERPEEDEKKEDDVEDGGDKDKLASSLESVKLPPSSEQVQAPAPKERTSSSSSRSGIPAWQLAAQS", "length": 425, "molWeight": 46589, "crc64": "5DCC4EDE593F40E0", "md5": "C35BFEE55DD9AA1E5CE91D076814513F"}}
{"primaryAccession": "Q9HGM2", "text": "This is Protein get1 protein, from Fission yeast, contains 171 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HGM2", "organism_name": "Fission yeast", "protein_name": "Protein get1", "length": 171, "firstPublicDate": "2009-05-05", "FUNCTION": "Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum, Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the WRB/GET1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MMDLIISTILLSLFIHFFDKFAKKRTIDGAYRIYVSVSNNKDLKKNKEILEQLLTVKKELNATSSQDQFAKWARLNRKYEQLSQEWEKQSANVKIFQDTFKRVLSLFLWILTRGFRFYIQFKESKTPVFFLPAFLLPSWALWVLSLPRSIYGSVSLTVWNFAVQKTISGIF", "length": 171, "molWeight": 20192, "crc64": "7A251A5F5E5F9FBF", "md5": "73EB5E73EC43F01775BE052944973052"}}
{"primaryAccession": "Q9LFS2", "text": "This is Protein GAMETE EXPRESSED 3 protein, from Mouse-ear cress, contains 641 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LFS2", "organism_name": "Mouse-ear cress", "protein_name": "Protein GAMETE EXPRESSED 3", "length": 641, "firstPublicDate": "2012-04-18", "FUNCTION": "Required for micropylar pollen tube guidance, Plays a role during early embryo patterning", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVAFRFVYIPLPFFFFFFFFFVFFSGVSQLQDQTATKKSVRILSKILIGDDGRVYACSDNDFFSFESNGSIAWSVHMNFKCNTDFAPVYSGFNQMLLLAENRILRVIFPRNGTKSEPELFFDPGETILGFAVSVSSSSVYITVKNHGLYAYNMFRQQLWIAEPKIERFGYRLGCRKDFDNCTFNSRPVIDSCEGSIYISNNEGELYSLSLRGTYYQWIQDFSLVDRFFTVTPGNNGLVYVVFPIKSLVFALDSFSGDILWQKTIGPLAETSASDPVIDSNSWASIGSLDGTLYSFSRTGDLYKIPKNAETDSVIQIEPLLDCSGYAVYVSQTKFEGMIDRVIEDYTYVSAKKPETAVFSLVVPETRSIYWSQSYSDQIPGLLLDEDLQHFVLDERIALAFVAASSSGNPFRCRSKHEKLSSSCSFAEPEHLDIYIGNERAIIWFLLFEFVIMVLFAALVRFCFIFWKKKKLQDRPFSTFLDKRRLLHRKSREIDKTITRLQNESTANESAVDKIGDLIQKRENVKRKLSSTYSLGRDIDESKSKLKDYVLPLYGGSSRSFSYRNRENESITIFQTPSDESSSEESYRDEHYDDVADDEHDEDDLDRKQKGKLLAHSEGSSNDGDGIASSRRSIYLKHIFDD", "length": 641, "molWeight": 73340, "crc64": "322B0A0CED11A8AB", "md5": "B1532EF510AF64E166CDDC46716C82A5"}}
{"primaryAccession": "Q9LIG6", "text": "This is NifU-like protein 4, mitochondrial protein, from Mouse-ear cress, contains 283 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LIG6", "organism_name": "Mouse-ear cress", "protein_name": "NifU-like protein 4, mitochondrial", "length": 283, "firstPublicDate": "2006-10-31", "FUNCTION": "Molecular scaffold for [Fe-S] cluster assembly of mitochondrial iron-sulfur proteins", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the NifU family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKGIARLVTSLSRIGGRKVVSGTSTVTSSSSSSLLLSRRSLFISATNLLNSRTKDSALPSLNSSLLAQKWNFLGGQRRTMFIQTQSTPNPSSLMFYPGKPVMEVGSADFPNVRSALGSPLAKSIYSIDGVVRVFFGSDFVTVTKSDDVSWDILKPEIFAAVMDFYSSGQPLFLDSQAAAAKDTAISEDDSETVAMIKELLETRIRPAVQDDGGDIEYCGFDPESGIVKLRMQGACSGCPSSSVTLKSGIENMLMHYVSEVKGVEQEFDGEDEEGTLSGEMRVE", "length": 283, "molWeight": 30504, "crc64": "FEB967EB8B5785A2", "md5": "013E84331791D777A564F8E95C958947"}}
{"primaryAccession": "Q9LK72", "text": "This is Lectin-like protein At3g16530 protein, from Mouse-ear cress, contains 276 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LK72", "organism_name": "Mouse-ear cress", "protein_name": "Lectin-like protein At3g16530", "length": 276, "firstPublicDate": "2014-05-14", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the leguminous lectin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQIHKLCFLVLFLANAAFAVKFNFDSFDGSNLLFLGDAELGPSSDGVSRSGALSMTRDENPFSHGQGLYINQIPFKPSNTSSPFSFETSFTFSITPRTKPNSGQGFAFIITPEADNSGASDGGYLGILNKTNDGKPENHILAIEFDTFQNKEFLDISGNHVGVNINSMTSLVAEKAGYWVQTRVGKRKVWSFKDVNLSSGERFKAWVEFRNKDSTITVTLAPENVKKPKRALIEAPRVLNEVLLQNMYAGFAGSMGRAVERHDIWSWSFENAAKNN", "length": 276, "molWeight": 30509, "crc64": "BAA4906B68FE6969", "md5": "669F82CD84E017530AAFFE8248836A4E"}}
{"primaryAccession": "Q9LLC6", "text": "This is Cytochrome b6-f complex subunit petO, chloroplastic protein, from Chlamydomonas smithii, contains 198 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LLC6", "organism_name": "Chlamydomonas smithii", "protein_name": "Cytochrome b6-f complex subunit petO, chloroplastic", "length": 198, "firstPublicDate": "2002-11-15", "FUNCTION": "The cytochrome b6-f complex functions in the linear cross-membrane transport of electrons between photosystem II and I, as well as in cyclic electron flow around photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the petO family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MALRCKTPAATCAARSRRSVRVSAHKGAFEQAQVAAAAFVAAAVIAAPANAGVVLQQPVLKKAFQDDTPAAPPPKREFRGLAPPALPQSDAPNVAAEKPKKAEVVESTSGGLDPRSVALPGALALTIGGFVAASKIDGSFNDWFMEAVVRDSNNYAGYEATLKSENGVTFPKVAAGGTKKVKAATGSKKGGFPFGGKK", "length": 198, "molWeight": 20247, "crc64": "E3369D9175C176F8", "md5": "0895E222B6085F6F60664CF1354C16BB"}}
{"primaryAccession": "Q9LNI5", "text": "This is MYB-like transcription factor ETC1 protein, from Mouse-ear cress, contains 83 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LNI5", "organism_name": "Mouse-ear cress", "protein_name": "MYB-like transcription factor ETC1", "length": 83, "firstPublicDate": "2013-07-24", "FUNCTION": "MYB-type transcription factor involved in epidermal cell fate specification, Acts as a negative regulator of trichome development, by mediating lateral inhibition, Promotes the formation of hair developing cells in H position in root epidermis, probably by inhibiting non-hair cell formation", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNTQRKSKHLKTNPTIVASSSEEVSSLEWEEIAMAQEEEDLICRMYKLVGERWDLIAGRIPGRTAEEIERFWVMKNHRRSQLR", "length": 83, "molWeight": 9831, "crc64": "3D4802F360042860", "md5": "79B2B024FBBBAA3A27411894423F0268"}}
{"primaryAccession": "Q9LTT3", "text": "This is High mobility group B protein 10 protein, from Mouse-ear cress, contains 319 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LTT3", "organism_name": "Mouse-ear cress", "protein_name": "High mobility group B protein 10", "length": 319, "firstPublicDate": "2010-11-02", "FUNCTION": "Binds preferentially DNA with A/T-rich content", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSTDISPPYSQTHVEPVNGYPSDNKRCDDSSVPAKYDDLVRNSALFWEKLRAFLGLTSKTLKVPTVGGNTLDLHRLFIEVTSRGGIERVVKDRKWKEVIGAFSFPTTITSASFVLRKYYLKFLFQLEHVYYLEKPVSSLQSTDEALKSLANESPNPEEGIDEPQVGYEVQGFIDGKFDSGYLVTMKLGSQELKGVLYHIPQTPSQSQQTMETPSAIVQSSQRRHRKKSKLAVVDTQKPKCHRSGYNFFFAEQYARLKPEYHGQERSITKKIGHMWSNLTESEKQVYQDKGVKDVERYRIEMLEYKSSHESGATASTVAQ", "length": 319, "molWeight": 36296, "crc64": "7802A12A69F7456C", "md5": "3C2A48BCB480FBB7266F010A463D7DDD"}}
{"primaryAccession": "Q9LY61", "text": "This is Nematode resistance protein-like HSPRO1 protein, from Mouse-ear cress, contains 428 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LY61", "organism_name": "Mouse-ear cress", "protein_name": "Nematode resistance protein-like HSPRO1", "length": 428, "firstPublicDate": "2011-07-27", "FUNCTION": "Positive regulator of basal resistance", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MADLDLQRKMVSPKLHVTIPEPCKLSSVSSPISSSSSAACSAYELYLRLPELRNLWSSLYFPHWISEPVLKPALQALEITFRLILTVASDTRPYINRREWIRRLDSLTTSQIKIVAAICGDEDNYEENVSAAPVSNGWSSLSLLSEIATCRTSESVGQKILSTIENEMRWCKYTLGLGEPNLAGKPYLQYDAVCLPEELHSLKNNPYADHIENQENQMLYTSHQILESWIYVSVNLLYRIESRIEEGKFEKASSDVYLLERIWKLLSEIEDLHILMDPEDFLKVKKQLQIKSTFPNDAFCFRSKGLVEMAKMSKELRQKVPAVLEVEVDPTGGPRLQEAAMKLYSRKTEYEKIHLLQGMQAVESAAKRFFFGYQKLVAAMIGNAEANANRTVANHESYDSLTQVFMEPPYYPSLDAAKTFLGEFWSQL", "length": 428, "molWeight": 48788, "crc64": "278D0A023953D07A", "md5": "80C3D7BEFC94CB73E2ADA45D44B03950"}}
{"primaryAccession": "Q9M069", "text": "This is Glucan endo-1,3-beta-glucosidase 7 protein, from Mouse-ear cress, contains 504 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M069", "organism_name": "Mouse-ear cress", "protein_name": "Glucan endo-1,3-beta-glucosidase 7", "length": 504, "firstPublicDate": "2005-10-25", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the glycosyl hydrolase 17 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALSISIYFLLIFLSHFPSSHAEPFIGVNYGQVADNLPPPSETVKLLQSTSIQKVRLYGADPAIIKALAGTGVGIVIGAANGDVPSLASDPNAATQWINSNVLPFYPASKIMLITVGNEILMSNDPNLVNQLLPAMQNVQKALEAVSLGGKIKVSTVNSMTVLGSSDPPSSGSFAAGYQTGLKGILQFLSDTGSPFAINPYPFFAYQSDPRPETLAFCLFEPNAGRVDSKTGIKYTNMFDAQVDAVHSALKSMGFEKVEIVVAETGWASRGDANEVGASVDNAKAYNGNLIAHLRSMVGTPLMPGKPVDTYIFALYDENLKPGPSSERAFGLFKTDLSMVYDVGLAKSSSSSQTPSGKVTSSGWCVPKKGATNEELQASLDWACGHGIDCGAIQPGGACFEPNNVVSHAAYAMNMYFQKSPKQPTDCDFSKTATVTSQNPSYNNCVYPGGGGGGGGGGGGSKAVMNKYVSSDKVEKKNGATEPKVSSSLSFLLIFLSLIFHVYM", "length": 504, "molWeight": 53121, "crc64": "77FF26A6AF36C167", "md5": "96BFFBB205A924815A8A483FAA40EF9C"}}
{"primaryAccession": "Q9M0X8", "text": "This is Transcription factor bHLH114 protein, from Mouse-ear cress, contains 298 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M0X8", "organism_name": "Mouse-ear cress", "protein_name": "Transcription factor bHLH114", "length": 298, "firstPublicDate": "2008-12-16", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTEEFEIAGISTGAWWSSPTNTAAVFSGYSLPCSTEISPDVTNFGWQNFDNKINDHNDGCMNMHNSFFEGLLIDPNDQLLPDPWSKSTIPNAKSELLENFPFLDNMFLVDSEAESLLDHEIRNHKSSKEQITQDYKNLTSKRSEELEENSDEYSPRLLKRPRLETLSPLPSFKVRKEKLGDRITALQQLVSPFGKTDTASVLNEAVEYIKFLQEQVTVLSNPEQNTIGSVQQQQCSNKKSINTQGEVEEDECSPRRYVDLSSRGLCLMPISASYPVAAAAASAAEMNVHLVSGIFHSL", "length": 298, "molWeight": 33345, "crc64": "6F6687145DDB4BA9", "md5": "79A0F5BF9316DB26DA4225A4E59B7F3C"}}
{"primaryAccession": "Q9M5P3", "text": "This is Cytochrome c-type biogenesis ccda-like chloroplastic protein protein, from Mouse-ear cress, contains 354 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M5P3", "organism_name": "Mouse-ear cress", "protein_name": "Cytochrome c-type biogenesis ccda-like chloroplastic protein", "length": 354, "firstPublicDate": "2010-06-15", "FUNCTION": "Required for the transfer of reducing equivalents from stroma to thylakoid lumen, Involved in the biogenesis of the plastid cytochrome b6f complex by probably transferring reducing equivalents from stromal m-type thioredoxin (Trx-m) to the lumenal thioredoxin HCF164", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the DsbD family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNLSVNRCITGGFVGGFSSCRLNHEKRWVRAGKHCELERERSLVSDAVSLERLESKSIKLAMLASGLGVANLVTLSSAKAADLKMIVLDQATSIYILAEGSLGDSVGNFLYSANQQANEAVQDQLSALSVTSLAVIFGAGLVTSLSPCTLSVLPLTLGYIGAFGSGKSRGQVIGDTVAFALGLATTLALLGIVASFAGKAYGQIGQGLPVAASGLAIVMGLNLLEIIELQLPSFFNNFDPRAAAANFPSSVQAYLAGLTFALAASPCSTPVLATLLGYVATSRDPVIGGSLLLTYTTGYVAPLIVAASFAGALQSLLSLRKVSAWINPISGALLLGGGLYTFLDRLFPAATMVM", "length": 354, "molWeight": 36530, "crc64": "7CB590C09BF0A6FE", "md5": "9D8DBFFE42A1D7EE05B3622280E01A76"}}
{"primaryAccession": "Q9P3B2", "text": "This is Respiratory supercomplex factor 2 homolog C1565.01 protein, from Fission yeast, contains 242 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P3B2", "organism_name": "Fission yeast", "protein_name": "Respiratory supercomplex factor 2 homolog C1565.01", "length": 242, "firstPublicDate": "2008-09-23", "FUNCTION": "Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKLSTPEEVKAFNRNTYSALFKGALVGSSLGIAGWLIGNRYSAGFRRLPFSLKSWLVIGSGSGASIIFADKAGLKFEAERYGKFDQIDYSTKGLPWNQRALYYFNEHKWPIILGTWASTMGLSLYAASRNRYDTAPQKLIQARMYAQGVTVVVLLGSVYLSTLANRLEPLEREVLVTDPSNPTKLVAFKQRKERYPGELQWEVLVSQDEERLRKLNLPLREPHGSTGPMSTPTPALNSSRSA", "length": 242, "molWeight": 27052, "crc64": "98603A0262AFC6AD", "md5": "297FA60F0A298F2ED9B94B4FE9E12D8D"}}
{"primaryAccession": "Q9P4E5", "text": "This is Lipase 10 protein, from Yeast, contains 465 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P4E5", "organism_name": "Yeast", "protein_name": "Lipase 10", "length": 465, "firstPublicDate": "2003-11-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKTLLIFLAFLSSIFASLIGLTPPSKDSFYSPPVGFATAKPGDILKIRNTPSAPSSLYLPIVVKNAWQLLIRSEDSFGNPNAFVATLIQPLNANPSKLVSYQSWEDASHIDCSPSYGMQFKSPATTVTTQIDMTLIVPLLQNGYYVIIPDYEGPKSTFTVGRQSGKATLNSIRAALQTGAFSGIKKTAKVALWGYSGGSLATGWAISLQSKYAPELKENLIGAAVGGFATNITAVAEAVDGTVFSGFIPLALNGLANEYPDFKKRLYGEVKLSARSTMEKGSQNCLAASLVGYPMSQYFTGQNRAFEKGWGLLQDEVFNKTIEDNLLLKLDKTYLPQVPVLIYHGTIDEIIPIKDANAQYQIWCDRGIQSLEFAEDLSAGHLAETFTGAPAALSWIDARFSGKPAVNGCQRTIRSSNVLYPGISITIRIYFEGISKTIFGVNLGSGVNADKSISNKFFAYIRKYI", "length": 465, "molWeight": 50469, "crc64": "969A90F0ACC71A6B", "md5": "C207526975CC06A8FA5C4DFBB08AF634"}}
{"primaryAccession": "Q9P4E8", "text": "This is Lipase 6 protein, from Yeast, contains 463 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P4E8", "organism_name": "Yeast", "protein_name": "Lipase 6", "length": 463, "firstPublicDate": "2003-11-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRDLILFLSLLHTIFASLFSLKPPSQDDFYKAPAGFKAAKPGDILKTRKSPNKPSSLYAPVDVQNSWQLLVRSEDSFGNPNAFVTTIIQPKNADPSKVVSYQNWEDASNINCSPSYGSQLGAPLSTILTQLDMTFIVPPLKSGYYVVLPDYEGPKSTFGVGRQSGKATLDSIKAVLKTKDFSGINDDAKVVLWGYSGGSFASGWAAVLQPEYAPELKDNLIGAALGGFAANLTGIAESVDGEVFSGFIPLALNGIANEYPDFKKRLYEEVKPGAKADLQKGAENCLAASLISYPMYQYFTGPRRVFEKGWSLLEDKTIGKTLEDNLLIALSKEHMPQIPIFVYHGTIDKIIPIKDSIKIYKNWCDWGIGSFEFSEDKSNGHTTETVVGAPAALTWIDARFAGKPAVEGCSFTTRASNFLYPNISESAASYFKGIYQTILRSKLGSGVTSDDVSVNGLRSLYHT", "length": 463, "molWeight": 50480, "crc64": "21F5E66B04F73DAF", "md5": "080EF7CD27F94F37C6E88F2EB971B697"}}
{"primaryAccession": "Q9P6I3", "text": "This is Putative mannan endo-1,6-alpha-mannosidase C1198.07c protein, from Fission yeast, contains 442 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P6I3", "organism_name": "Fission yeast", "protein_name": "Putative mannan endo-1,6-alpha-mannosidase C1198.07c", "length": 442, "firstPublicDate": "2004-08-31", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the glycosyl hydrolase 76 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRYLSFFFEFFFLFSFAFAFDFDVTSDDSINSALTTVTDGMLNYYQSTSHTFTAYWWMTGAGLNSMTDTYAATGNTTHLDMLISALVANKGDNNDYAPNSEKFDLGNDDQGIWGLSAMSAAEVNMTTGDSSASFTELAQAVFNEIMSRWDTSSCGGGVRWQIYSFNNGYSYKNSISNGILFQLAARLARYTNNDTYVDLAQKVWDWSTTVGFVDLDDYTVYDGASVTSNCSSITNEQWSYNVGVYLAGTAFLYNYTNGSSVWQTHMEGLMNKALDYYFTSDKIIYEPSCEPTESCNSDQTAFKGMLARFLGYTMQLAPYTVETILPYIQSSAEAAALACSGGSDGVTCGYMWYWNNGTWDDHYGLGEQISAVETFQALLAQQSATILTLDTGASSESNPDAGTDDGDTVTITPATKSDKGWAGFLTFAFSFVFLLFSIWLYF", "length": 442, "molWeight": 48877, "crc64": "E5D2F9EEAFCF749A", "md5": "32F06AAF4031C73F89A9A190074CAAC2"}}
{"primaryAccession": "Q9P6I8", "text": "This is Zinc-type alcohol dehydrogenase-like protein C1198.01 protein, from Fission yeast, contains 423 amino acids, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P6I8", "organism_name": "Fission yeast", "protein_name": "Zinc-type alcohol dehydrogenase-like protein C1198.01", "length": 423, "firstPublicDate": "2009-01-20", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the zinc-containing alcohol dehydrogenase family, Class-III subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEYLTNLKTNIMDKQLGHREVSEGSTQPKPDPSGATMKACVWDGPLNVKIAEVPKPTITHPKDVIVKTTACTICSGSDSHIFSGEMPGIEKGAILGHESCGIVAEKGDEVNNLEIGDRVVIAFDLACGQCSFCKRHEYAACDTTNDSKLMDVNYGSHHSAIFGYTKLLGDVPGCQAEYIRVPFAEINCCKLPDDIPDSEGLFMSDVLCTSLHACTLGEVKKGDTVAIWGMGPIGLYAGRWAQILGASKVIGIEVVPERIELARQKFGFTVIDRNEVSDVPKKIMELVSNGVDCAIEASGFRFSTSILHKVERAVGLETDSPDMITECLNAVRKYGHVSIIADYVGTSNQFPIGHVVMKHLTIRSGQCPCQNYFGYVIDNIRSGKIDPRWMVTNKIKFDDLPDAYNKLFYKEDGYVKVYCDMTE", "length": 423, "molWeight": 46442, "crc64": "4A598CF6841CF285", "md5": "D4B45A600863B882B20FCABF824BBD0C"}}
{"primaryAccession": "Q9P6R6", "text": "This is ATP synthase subunit delta, mitochondrial protein, from Fission yeast, contains 167 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P6R6", "organism_name": "Fission yeast", "protein_name": "ATP synthase subunit delta, mitochondrial", "length": 167, "firstPublicDate": "2003-01-10", "FUNCTION": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain, F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk, During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation, Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element, Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the ATPase epsilon chain family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFRLSNYMLRKSQFPQGLVRAPFGIRGYAQAVQKNEKLVLSMALPYQTIYEKVPVTQVDIPAEDGEMGILKDHVPMIQCLKPGVISVTDESSNKSKYFISGGFAVQQPSNELSITVPEAYKLEDFSSSVANQLLEKHKAEMNSSDEGVAAEAAVRVSVLESLVRALK", "length": 167, "molWeight": 18410, "crc64": "F71DA9E55848FD58", "md5": "B4F922936867838643DE955F91F23E79"}}
{"primaryAccession": "Q9P792", "text": "This is ZZ-type zinc finger-containing protein P35G2.11c protein, from Fission yeast, contains 397 amino acids, has 3 ZZ-type Zinc finger, locates in Golgi apparatus.", "functionDomainRange": [{"location": [57, 112], "description": "ZZ-type", "keyword_description": "Zinc finger", "textural_description": "ZZ-type Zinc finger"}, {"location": [131, 182], "description": "ZZ-type", "keyword_description": "Zinc finger", "textural_description": "ZZ-type Zinc finger"}, {"location": [207, 258], "description": "ZZ-type", "keyword_description": "Zinc finger", "textural_description": "ZZ-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9P792", "organism_name": "Fission yeast", "protein_name": "ZZ-type zinc finger-containing protein P35G2.11c", "length": 397, "firstPublicDate": "2008-01-15", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {"ZZ-type Zinc finger": 3}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLCNRTCPSSDCGILCNHSVPSFPPFHSSVANIHFTKENNLKSNIFEHNNNSPTLRSSSVACNTCLKIIRNDSFHCTKCFDFDVCRDCYAKQAFLHPCPKPHFVLVRSSIPSVASLTCSVNSMSVSPQSNFMYAICDHCEQPIHNVRYKCSVCDDYDICESCLTDNSHSNTHAFVRITKAYPHGLPSFHLFPQFLSAELFESASTVHRSVQCDNCLAHPIVGPRFHCLVCEDYDLCSSCVSHVHHDHHSMLRLTREISASPLHLSKPEKPKVLNFDFKLVEDSILPLELSPGCPFYKIWHIRNTSCQSWPSPLYVKFNGGDKLFPGDNPYSFPITSSVHPGEDVNFTVALKVPEKSNKEIFTAFFNICSDDGSVFHKSLCAFLRVPKSFSRISKSSF", "length": 397, "molWeight": 44659, "crc64": "486C219E44B1D515", "md5": "B672C2404235B5B0D9F496D9E0B21D86"}}
{"primaryAccession": "Q9P7C1", "text": "This is Uncharacterized J domain-containing protein C2E1P5.03 protein, from Fission yeast, contains 303 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7C1", "organism_name": "Fission yeast", "protein_name": "Uncharacterized J domain-containing protein C2E1P5.03", "length": 303, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DnaJ family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSRIFILLLLFGVCLAWTSSDLEIFRVVDSLKSILKNKATFYELLEVPTKASIKEINRAYRKKSILYHPDKNPKSKELYTLLGLIVNILRNTETRKRYDYFLKNGFPRWKGTGYLYSRYRPGLGAVLVLLFLLISIAHFVMLVISSKRQKKIMQDHIDIARQHESYATSARGSKRIVQVPGGRRIYTVDSITGQVCILDPSSNIEYLVSPDSVASVKISDTFFYRLPRFIVWNAFGRWFARAPASSEDTDSDGQMEDEEKSDSVHKSSFSSPSKKEASIKAGKRRMKRRANRIPLSKNTNREN", "length": 303, "molWeight": 34787, "crc64": "95C1704E47511382", "md5": "1A2CAA76249DBB9790B79C4E014D2DC6"}}
{"primaryAccession": "Q9P7C8", "text": "This is DNA replication complex GINS protein sld5 protein, from Fission yeast, contains 214 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7C8", "organism_name": "Fission yeast", "protein_name": "DNA replication complex GINS protein sld5", "length": 214, "firstPublicDate": "2006-10-31", "FUNCTION": "The GINS complex plays an essential role in the initiation of DNA replication, Has a role in chromosome segregation and is required for bir1 localization", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the GINS4/SLD5 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEWDADDLLIEPTTEVENDYEDLCTQWVNERMAPDLLPFAEEIVSRVLDRIEAQRETLQLAIGTSSATSYRSVLMQTELERVKFVLRSYMRTRINKIDKYAQYIQSHPNLLLYLSSPERQYLLRHQQIVHRHYMDSFLREVPAKMNKLDDKVGNLSMVASPDMDTAVFCVVNESVEENFRVSENEYITLDKGDVLILRYSVISDYLRLGVVSLI", "length": 214, "molWeight": 24989, "crc64": "9B1C7E50A471891F", "md5": "9A2796D843774CC7FF9DE739856EF211"}}
{"primaryAccession": "Q9P7D0", "text": "This is Uncharacterized protein P4H10.19c protein, from Fission yeast, contains 381 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7D0", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein P4H10.19c", "length": 381, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the calreticulin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQTLLFYFFFINLIFAHDLNVKTYKPCTIPSVFSEQFTSEDITTWRSRWRAPVNKDLGVWDLVEAPGSHLRDEYGLITLKSNKPHILISNLENPTTRQSSSVPIVLSFQVKPTKPWTCGHAYVSLVHQSNPKNVSKEPPSVIRFGVKKCGMFDYISLSIISYDGKVSCHLYDAPPSGLVEGRTSMYTLLLQNTTVVIRRDQSVVYTGDVGTNFFHSPTKWITHSNVSNGYYTSRNIMSFLLSNNTNTSSYPFSVNGVELDVWNENAGVFINNIYFGFSLSDAMKFENETFIAKKILENSPCPNQPSIQPFGILMMLVSTIYGNFKNLYNCIKRNTIGYIYNSIYDFWITEGMLFPMRNMDIFKITAISIGLSIPVFLWLLK", "length": 381, "molWeight": 43418, "crc64": "52C9521E7D9947B3", "md5": "6C13E870F587345A1746C15E470D4188"}}
{"primaryAccession": "Q9P7W9", "text": "This is Probable ribonuclease P protein subunit 1 protein, from Fission yeast, contains 217 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7W9", "organism_name": "Fission yeast", "protein_name": "Probable ribonuclease P protein subunit 1", "length": 217, "firstPublicDate": "2004-03-29", "FUNCTION": "Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the eukaryotic/archaeal RNase P protein component 1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MADPLYSSLKTVNSTSKVTPESLVFQTKILTPEEAKNVINEKIAFKPLLLVPSLNLEKQGDRKESVASKKRKKLSSKEKKKLQLNVVPKIADYSQFKHLHSMWCSYILEVIAGCTGESLMAKLAKAEYQGAYMQVLRSKSTTRVGLEGICIHESKHMLSLITKENRVVRVPKQDSVMKVIVDVPQRKLVFELYTQHLLLRAGDRSNKRFKSKNTIDL", "length": 217, "molWeight": 24629, "crc64": "441B0EADE8E8A7CD", "md5": "268955F9EEFC1422E1DFA8D31C1EAE91"}}
{"primaryAccession": "Q9P7X3", "text": "This is Protein frg1 protein, from Fission yeast, contains 245 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7X3", "organism_name": "Fission yeast", "protein_name": "Protein frg1", "length": 245, "firstPublicDate": "2001-09-26", "FUNCTION": "May have a role in processing of pre-rRNA or in the assembly of rRNA into ribosomal subunits, May be involved in pre-mRNA splicing (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the FRG1 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSMRLTFKGDKKIQKKKKKNTKSLQSSLESAENDPFWTDANELNELEGPAVIYKIDDDAGVSLGIEEVKESCVLLPLDKVSLEPELTRQVFLLSILNNTILLKSCLGKYMSCSKSGDLYCTQEAVGSQEQWIAENLGSGFWAWKSVSTKKYLTLSREKQDQAIACVSDTVIPEAKWRIRVQTRFLKKNKSSLFDNPTIHSRQLESMAGRKLSTDEKKTLKKAFKEGVLHEALLDLRVSSRSDKYG", "length": 245, "molWeight": 27675, "crc64": "C322E1C0D0A1A798", "md5": "3A0DAEAA36471F2B6F130E74116A49C5"}}
{"primaryAccession": "Q9P8V9", "text": "This is Lipase 8 protein, from Yeast, contains 460 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P8V9", "organism_name": "Yeast", "protein_name": "Lipase 8", "length": 460, "firstPublicDate": "2003-11-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLFLLFLLITPIYAGLIFLTKPSNDPFYNPPKGFEKAAVGDILQSRETPKSITGRFAPLEIQNSWQLLVRSEDSFGNPNAIVTTVIQPFNADPSKVASYQVFEDSAKGDCAPSYALQFGSDLSTLATQAETFLLAPLLEQGYYVVSPDYEGPKSTFTIGKQSGQAVLNSIRAALKSGKITNIKDDAKVVMWGYSGGSLASGWAAALQPSYAPELGGNLLGAALGGFVTNITATAQAADGTVFAGIVANALGGVANEYPEFKSILQSDTDKKSVFDEFDSHCLADGVIDYINTSFLTGDNKIFKTGWDILKSSTIAKIVKDNGLVYQKQLVPKIPIFVYHGSIDQIVPIVNVKKTYQNWCEGGISSLEFAEDGTNGHLTETVVGAPAALTWIIDRFNGKQTVSGCQHDKRLSNFQYPNISSSILKYFKVALDTMMSNGLGSDIQKDKITPDDLRKFLLGGW", "length": 460, "molWeight": 49731, "crc64": "C9C48CFDDEFBC577", "md5": "9BE550E39DE69E13B918DAE553CCA9DE"}}
{"primaryAccession": "Q9P8W1", "text": "This is Lipase 4 protein, from Yeast, contains 459 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P8W1", "organism_name": "Yeast", "protein_name": "Lipase 4", "length": 459, "firstPublicDate": "2003-11-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLFLLFLLVAPIYAGLILPTKPSNDPFYNAPAGFEKAAVGEILQSRKTPKPITGVFVPVKIQNSWQLLVRSEDSFGNPNVIVTTVMEPFNADPSKLASYQVFEDSAKADCAPSYALQFGSDVTTIATQVETYLLAPLLDQGYYVVSPDYEGPKSTFTVGKQSGQAVLNSIRAALKSGKITNLAEDAKVVMWGYSGGSLASGWAAALQPNYAPELGGNLLGAALGGFVTNITATAEATDGTVFAGIMANALGGVANEYPEFKQILQNDTDKQSVFDQFDNHCLADGVINYIGKHFLSGTNKIFKSGWNILKNPTISKIVEDNGLVYQKQLVPKIPILIYHGAIDQIVPIVNVKKTYQNWCDAGIASLEFSEDATNGHITETIVGAPVALTWIINRFNGKQTVSGCQHVKRTSNFEYPNIPPSILNYFKAALNILIQKGLGPDIQKDQVNPDGLKKIPILV", "length": 459, "molWeight": 49580, "crc64": "D38354ADB6FE1F5D", "md5": "7304CBA8E7EC81CE406CF09E9D70DB68"}}
{"primaryAccession": "Q9SFE9", "text": "This is GDP-mannose transporter GONST5 protein, from Mouse-ear cress, contains 341 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SFE9", "organism_name": "Mouse-ear cress", "protein_name": "GDP-mannose transporter GONST5", "length": 341, "firstPublicDate": "2011-03-08", "FUNCTION": "GDP-mannose transporter that may be involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the TPT transporter family, TPT (TC 2,A,7,9) subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEEGSLWRQWTMFRSLLSILQWWGFNVTVIIMNKWIFQKLDFKFPLSVSCVHFICSSIGAYIVIKVLKLKPLIVVDPEDRWRRIFPMSFVFCINIVLGNISLRYIPVSFMQTIKSLTPATTVVLQWLVWRKYFDWRIWASLVPIVGGILLTSITELSFNVFGFCAALFGCLATSTKTILAESLLHGYKFDSINTVYYMAPFATMILGLPAFLLERNGILDWFEAHPSPWSALIILFNSGVLAFCLNFSIFYVIQSTTAVTFNVAGNLKVAVAVFVSWMIFRNPISPMNAVGCGITLVGCTFYGYVRHMLSQQQPGTPRTPRTPRNKMELIPLVNDKLESKI", "length": 341, "molWeight": 38848, "crc64": "C2BB40C25C98E78F", "md5": "54F5405164A610356F26BB4FAFFC177E"}}
{"primaryAccession": "Q9SLK0", "text": "This is Peroxisomal isocitrate dehydrogenase [NADP] protein, from Mouse-ear cress, contains 416 amino acids, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SLK0", "organism_name": "Mouse-ear cress", "protein_name": "Peroxisomal isocitrate dehydrogenase [NADP]", "length": 416, "firstPublicDate": "2013-04-03", "FUNCTION": "May be involved in response to oxidative stresses", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the isocitrate and isopropylmalate dehydrogenases family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEFEKIKVINPVVEMDGDEMTRVIWKFIKDKLIFPFLELDIKYFDLGLPNRDFTDDKVTIETAEATLKYNVAIKCATITPDEARVREFGLKKMWRSPNGTIRNILNGTVFREPIICRNIPRLVPGWTKPICIGRHAFGDQYRATDLIVNEPGKLKLVFEPSGSSQKTEFEVFNFTGGGVALAMYNTDESIRAFAESSMYTAYQKKWPLYLSTKNTILKIYDGRFKDIFQEVYEANWRSKYEAAGIWYEHRLIDDMVAYAMKSEGGYVWACKNYDGDVQSDFLAQGYGSLGMMTSVLVCPDGKTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRAKLDSNAALLSYTEKLEAACMGTVESGKMTKDLALLIHGAKVRRDQYVNTEEFIDAVAWELKRRLLGNNSRL", "length": 416, "molWeight": 47234, "crc64": "EEAAAC9E5C6B2FA5", "md5": "76FE1BE6856A1283B40D182D4152BA24"}}
{"primaryAccession": "Q9SR70", "text": "This is Peptidyl-prolyl cis-trans isomerase FKBP16-4, chloroplastic protein, from Mouse-ear cress, contains 230 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SR70", "organism_name": "Mouse-ear cress", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP16-4, chloroplastic", "length": 230, "firstPublicDate": "2012-03-21", "FUNCTION": "PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the FKBP-type PPIase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MILTMKLVHPLHHSLSSSIPFPSRKRQSKPYRCSLPSPGCEKVIRTETVLPPAPVSCEGRRVLLGCLLATASGILSTGSAEAVSTSRRALRASKLPESDFTTLPNGLKYYDIKVGNGAEAVKGSRVAVHYVAKWKGITFMTSRQGLGVGGGTPYGFDVGQSERGNVLKGLDLGVEGMRVGGQRLVIVPPELAYGKKGVQEIPPNATIELDIELLSIKQSPFGTPVKIVEG", "length": 230, "molWeight": 24504, "crc64": "A3B3A3F868A49F64", "md5": "37DBC81A51CE8142AA04C972E2D8A59A"}}
{"primaryAccession": "Q9U7D3", "text": "This is Warthog protein 5 protein, from Caenorhabditis elegans, contains 176 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9U7D3", "organism_name": "Caenorhabditis elegans", "protein_name": "Warthog protein 5", "length": 176, "firstPublicDate": "2006-12-12", "FUNCTION": "Intercellular signal essential for a variety of patterning events during development", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MCSMWLMASWLMAFVAGSTLADYCGDHKVPFGMEVHKNGNVNILCSRPSCHEKKYAECPERATSTTCSTNSSWVGGVTQHSDGSLRLMCCEYDLLPTYSTIQYEKLTIRTGEYFEGDEQMEGDVVTAFDLIGNIEQVKEPDGKYSYNLLIYRYHCGNIPDTPPAWYMKKQWPYWEK", "length": 176, "molWeight": 20134, "crc64": "08AE43250576D7C3", "md5": "FEC9FE438ECB06505D6C806B12A922FC"}}
{"primaryAccession": "Q9US47", "text": "This is Putative succinate-semialdehyde dehydrogenase C1002.12c [NADP(+)] protein, from Fission yeast, contains 547 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9US47", "organism_name": "Fission yeast", "protein_name": "Putative succinate-semialdehyde dehydrogenase C1002.12c [NADP(+)]", "length": 547, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the aldehyde dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTSLIQSIPRYIYESNSLPKLIRSGLDRKSPIGLSLLKRNCRNRSFAANMSTSSKLSTNIKDLSLFDLEEFPARSYIGGKWVTAASGKTFDVENPGLNETLAPVTDMSVEETRKAIKVAHEAFLSYRNSDIKERYAILRRWYDLIMENADDLATMMTLENGKALGDAKGEVVYAAKFIDWFAGEALRISGDSSMSSNPQNRIITIKQPVGVVGIITPWNFPAAMITRKVGAALAAGCTVVIRPAAETPFTALALAKLAERAGVPAGVLNMVTANSPSEHGIELTTNPLIRKVSFTGSTNVGKILAKQSSSTLKKLSLELGGNAPFIVFEDADLEKAADALMACKFRGSGQTCVCANRIYVHSSVYDAFVDLVTERVSKFKLGYGLDAGVTHGPLISEKAISKVKQHVEDAVQKGGVVVTGGKVASNLGPMYFEPTVIINAKQGMLISEEETFGPVGALFKFDTEDEVVAWANDSPVGLAGYLFSKDISRVFRVGEALQVGMVGCNTGLVSDVLSPFGGVKESGFGREGSKYGISEYLDIKSLTISTL", "length": 547, "molWeight": 58834, "crc64": "8AD9B9A48C768252", "md5": "5675A72B199C90A40D887C531CF8DA19"}}
{"primaryAccession": "Q9USY4", "text": "This is ARS-binding protein 2 protein, from Fission yeast, contains 527 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9USY4", "organism_name": "Fission yeast", "protein_name": "ARS-binding protein 2", "length": 527, "firstPublicDate": "2001-08-14", "FUNCTION": "Binds, preferentially, to the Maundrell ARS consensus sequence within ARS3002", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNFYSLLPSRHDVSADNITEKFCQFCLCCNPWYAGADTRQLANAFNMIPKSEGQKFEIWVLFLLVRQYHQKIINSWSKLVGFLGVERKDEQSTQKIQQYVVRLKRWMSQTHVDAFFDYLLNKPNPYYLEIPETQPQVRCNVNVTDDLVIKSLRAGLMSHPDVNSSSISTMRTSTSPSNWIHSASASLDDNTHNLGSFVTNPHADSQECPTPQSLLMRASHHMSERGSQQAHQTTPQNHSLPHPPNMFEPPDEDHQLPSAANNSHNHDHAFQTAEAVGVADSIDPDWHQWPDDLRDVSSPKESDGLNDSWSRQTNQVETENVENEAGVPRKRGRPPGARNKIKRLRSEPSVSLTLSISWYERFEKLMHAQNTMLRSAFSHVARLPMETVSQLLSHYTETISQYLPPSETSPIPKTPNFKFISSTLLALVSSHSEILEASTDRLIWTVHQGPLTATICHAFNLEKAPSMHSLAEAQMIPDVPISHSNSMEPLDTVSSLKLEIAKLNAALKEKNLELENLKRKIMNAVFD", "length": 527, "molWeight": 59629, "crc64": "2860AE683999B9F4", "md5": "E960ABF43036A48176014208EC92BC0A"}}
{"primaryAccession": "Q9UT77", "text": "This is Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial protein, from Fission yeast, contains 526 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UT77", "organism_name": "Fission yeast", "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "length": 526, "firstPublicDate": "2008-01-15", "FUNCTION": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria, The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the GatB/GatE family, GatB subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSFGRWAASIGLEIHLQLATVKKLFSPAKVNPLAQPNTCVAYFDVSLPGSMPILNPEALKFAVKGALALNCEVANVCKFDRKHYFYPDLPAGYQITQKEIPIGRNGFIPLSAGLDNVPDTQIPIQHIQLEQDTAKSTSAKNPSRILLDYNRAGTPLLEIVTKPCFHDVNTVSAFLFKLQSIVRFAGISEALMENGGMRCDVNVSIAPVISSENLNELHFKNNGVISVEKSISHFPQLGTQLARVELKNLSNVRNVVNSIRHEVDRQVSLANMGVSWPSETRGFDDITGKTFPLRNKTTSDDYLFLPETDIPPIILSRSYVNSVLKSLPALPDELFQKLTTGSHAISHKEARTLLSVKEYYHYYRNAYHHIDSISHVNQSLKEDALRTLPYWITVELVGKVREIDPSPNINIVPPLQLADIVLLVSKKKLTAASAKLFLRSLIKSPSSKPISTLIQEKNFGTIGDSEKIKACVESVLSKHSKQFEELKNGKTSLIKWFVGLTMRELRGQASPKDIEMEVQSSLRREK", "length": 526, "molWeight": 58608, "crc64": "6EC626D0B38DC60A", "md5": "1C89AB31648A3429D07C013009B491C1"}}
{"primaryAccession": "Q9UT83", "text": "This is Meiotically up-regulated gene 28 protein protein, from Fission yeast, contains 609 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UT83", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 28 protein", "length": 609, "firstPublicDate": "2007-02-20", "FUNCTION": "Has a role in sporulation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MIALEKLSEKNKRSTKKCEISIYVGNLPSTCQSSDLHELFEPFGNFSKFHMLSRKKNKSTDSKSPTLFAFITFENKCSADNAIASLNGSSFQGNTLKVEYTHIVERYKNKLENGVDQIHHSNNEKAKIRFSKIEKYTKETRPTVSEVRVSTKDKKEYSMNTSNLVQSNPPKVHDKENAFAEATGTSILSSKAVQTLLVSDFTENEPKHLSIRPNCKDNNTPSISNTFIEPYKENNTEHLHLKSAFEPCQMMPGMLLEQNPQFLYDNPSIFVIGILNLPLKVSPVELYNEFSNHGHILGVAINQSINEDMTHYAEVAVSTYESCIEIIEKFHAIAYEGSILQLFIKQPVQGFCSNLLNHPEGTMTNLLPPNMEMPQPFEIPVIAKTSALPNPFISFPSFQTSYETTVTPTPTSTPTIDPCNLFVKNLDDNIVGNTQQLEELFSKFGRIKSCTLASYPSTEISKGYGFVSFSHPFEAVQAINTLNGVLFGKKRLFVNYAEKREDRKKRLSAIFSQSYPPVVPSPSLTIPMATEPQILEYHQEWPQPLIQSIQQHGYSDPRQTLPTRLDSCAAKLREAVISNENLNPSHKFGIKHSTFKTSLSPLTNIVLNQ", "length": 609, "molWeight": 68548, "crc64": "0ADE9A51603AB8F3", "md5": "1939D35FBD94167B94DB61FA30CF1085"}}
{"primaryAccession": "Q9UTM8", "text": "This is Putative succinate-semialdehyde dehydrogenase C139.05 [NADP(+)] protein, from Fission yeast, contains 493 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UTM8", "organism_name": "Fission yeast", "protein_name": "Putative succinate-semialdehyde dehydrogenase C139.05 [NADP(+)]", "length": 493, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the aldehyde dehydrogenase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAPQFKRPELFGFDKSHAQSFVQGKWISSPNNKTFEVDNPATGEIIGKVADVSVEETKKAISAANEAFKTYKNFTHVQRSQLLERWAELIMENKDDLVKMLTLENGKPLSQAEMEVTTCSGYLKWYAAEAVRTFGDVAPSSLQSQNFLISIKQPVGVSALITPWNFPAAMIARKGGAALAAGCTAIFLPAFRTPYVCLGLVRLAQEAGFPDGVLNVITSSDASAHGKELTTNPIVRKVSFTGSTNVGKILMGQSASTIKKVSMELGGNAPFIVFPDFPIDQAVESFCTIKFNSCGQVCVCPNRVYVHKNVYDEFVSKLTEKVKTIKVGDGFDSSSAVGPLISQDGCKKVSKHIEDAVSKGAKITVGGKEISSSKGYFFEPTVLSGVTQDMLVASEETFGPLASVFKFDDTEEVIEWANDSDVGLAGYVFTNNLSTMIHVAKELEVGLVGANIEMVDEPFISFGGIKQSGFGKEAGRLGVQEFMVVKEINLKTL", "length": 493, "molWeight": 53306, "crc64": "203BC61AA4F20A9B", "md5": "DE3BF7F4E7EC546DAF3A31778304355E"}}
{"primaryAccession": "Q9UTS5", "text": "This is Zinc finger protein zas1 protein, from Fission yeast, contains 897 amino acids, has 2 C2H2-type Zinc finger, has 1 C2H2-type 3; atypical Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [26, 50], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [56, 79], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}, {"location": [93, 119], "description": "C2H2-type 3; atypical", "keyword_description": "Zinc finger", "textural_description": "C2H2-type 3; atypical Zinc finger"}], "meta_data": {"primaryAccession": "Q9UTS5", "organism_name": "Fission yeast", "protein_name": "Zinc finger protein zas1", "length": 897, "firstPublicDate": "2006-01-10", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"C2H2-type Zinc finger": 2, "C2H2-type 3; atypical Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSNEESFTEKPLKKRSRAHRLGDPRFYCTYPDCPKSFTRKEHLRRHERTHENVKAFSCSFCNRAFARSDVLNRHVQQMHLQKQNLSERRMLNASCFLGFCVLAHDYVNLINARHFMIEHFLSLFAFCRTILFSLLTSFLLVPPPQFFHSEAGERPTPSVGAPSSLASSMDSVRVAPSMLAASHQIVPQYSENNPRVSNEPPRVTIENASLKPFSGYIKSHMSTSNFLNGEPDLNVNVDLSPFPNLPATVPITQAASTANAFQQPSNQFQTQKLPSGLDTRPVSSYPDELTQLESNPDSFSRLDLQGDCTCIFKNRSSIASSRTMDDVVRWLFSSGKRRQKYESSYPYQTQSNQIPSQDQYSDTDSNFLSYYFSASGPMYVPQKCPATVYNNLLNFLEGSFHLQPNFLAMFTLESVSSWLNAYWSMFHVRWPILHRGTFQITQAPLDLLLSMITLGMHSSNDLSIRSLAVEIHTTLRYNIYQKQEFGPPVSLWVYQALFLIQVFELFTSNLKQHRLAQMFHPVLIEAMRQAIPSDALTVRSETFGESNTPLTLQQWHKWITRESVKRIAFFVFALDSTSTLVFGNQPLLYVTDVSMPLLAEEHHWEAENFEVWAAQKPTIEPPTILHMLKAFVQCEQCESPLPKLSPWNMLLLLHGLLSVDISLKQKKFVPGMKLSKREIDGWCSLVFEAYQKWNRCYYSIFLNNNILPFGHPFVKECRSLYNLACIYSKTRLTYLQAFAKAVTDPVDGSVTSKTVAPLRYVKIWANTENARYSTSNALEILDMLLREKIESAPRYDTLIYHSWCYYVAALVLWSIGFALDEENKKTEEVTNLHSQMSRYVTKVRQALEQGEPLFAVVEKSKNPIILHVVLQALDVFPWDLLGEHKKIIQQLLSKGND", "length": 897, "molWeight": 102817, "crc64": "4B9F49DFBF6DA865", "md5": "57188A2DB9389CB839A7DB0282554D94"}}
{"primaryAccession": "Q9UUK3", "text": "This is Ubiquitin thioesterase otu2 protein, from Fission yeast, contains 324 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UUK3", "organism_name": "Fission yeast", "protein_name": "Ubiquitin thioesterase otu2", "length": 324, "firstPublicDate": "2008-02-05", "FUNCTION": "Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRCPLAYYYTQTTIPTQQKRKSKKMEELLSKQREECKELQSKITNLRKQLKEGNKKQKRALQQKISQMEADLSQKHATERQKLDKGDEETNETQQEDLLNTLLQQMEDTKITTAEKSSVQSSLNTKENTPQQPKKSRNRQKERLERRKAEMKKMSEQAELESEKMADLKNEEKKKFSKILEEAGLVAVDIPADGNCLFASISHQLNYHHNVKLNSQALRNKSADYVLKHCEQFEGFLLDEESGEVLPVSDYCNEIRNNSKWGSDIEIQALANSLEVPVHVYNTEGPVLKFNPSTVKFEKPLCIAYYQHLFGLGAHYNSLLYRDN", "length": 324, "molWeight": 37516, "crc64": "48BBB435960D4B9C", "md5": "BFE7E3B66BD438597888C78B35F1135F"}}
{"primaryAccession": "Q9VMD6", "text": "This is Protein real-time protein, from Fruit fly, contains 659 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VMD6", "organism_name": "Fruit fly", "protein_name": "Protein real-time", "length": 659, "firstPublicDate": "2005-04-26", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVQKFQSPVRVYKYPFELVMKAYERRFPTCPQMPIVLDCEVIKDESLEDGAKRNTSRRCKLAVDAPYIFKKLIGVDHVYFLQHNFLDLANRTLSIEAVNESFSSRIEIFERCRYYAHPDNSEWTCFDQSATLDIKNFFGFEHSMEKMGMKQYTQTTLKGKEIIEFFIGQLREEGITHVERWTSPSDATKSPTLDQASDQQHSILLDGDFIARSLGQLSPMQESKLLELRKMLDGVDDLERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRREHRIDALLAEYSKPAVVVEHFPGGWHHLDKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHICEEGIQKINESAERLEKPVLNWSLLVDLEGLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKFLFYGPDCAHMKDGLAQYLDEEIVPDFLGGPCKTMIHEGGLVPKTLYKMNSLEDHDDEVTAELPTTAAAQALVPGKRLSANQQHDHRNLYKSVDLKAGFAHELLIRNEDPKSVLTWDFDVMRNDLHFTLYRVTQELPEKNDSAVSYFDLQDFVEGVNYFREEPTLICRHKESVQGSHVMHHNDSYLMHWFSPSGAQLNVFYEVLSSANYKGSMTSLQSAFSSNSSAASSVQSR", "length": 659, "molWeight": 75679, "crc64": "3E6D07E266081080", "md5": "65AFE4B98EFB59DB8260CB6AEFA72E3E"}}
{"primaryAccession": "Q9VW27", "text": "This is Protein Teyrha-meyrha protein, from Fruit fly, contains 717 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9VW27", "organism_name": "Fruit fly", "protein_name": "Protein Teyrha-meyrha", "length": 717, "firstPublicDate": "2016-06-08", "FUNCTION": "Required for the correct synaptic targeting of motoneurons RP5 and V to muscle 12 (M12) (PubMed:20504957), May be involved in the negative regulation of Tl in M12 (PubMed:20504957), Involved in the correct patterning of veins in the proximal (costal) region of the wing blade (PubMed:17028348)", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MESNAFGSSHLPSQALVVLSEAASGLHEALRGQRPFPSRVIPFDFPLLQLPDAKDLHNMSLVGNYFNPHLLLNHGMLVANGAAAAAAAAGAGPASYFASDRSPLGKPSVLSNFSLPSAFSPPKYIGISLDQNLFNGSESFRTDSASPTCTSHESMEGSQDYDAVEKGESPRSNNSQDPRDLRHLHNAGKSHQALATSSSASSSSSSSCSTSNPAISTATSSVAVSMASHLAASSPHHHPHTHAHSHPHPLAHPHAHSHHHVGHHVGAPPVSTAVTTHHHMAHPHPLSHHHAAHHAALASLSMAGLRAVPGGLSLVSGLQAAAAGGAIPEMCPVCGLKLSAEEWHTHFLTELDRLYKLSAGFERASLQATYMFAPPCPAQENAIRTSHNRWETFQRIRNNRQNRLRLKVRKRKYGEMYMMESLYCSSCPICKRKYALETGKIPPEDDAKSQEEIETVDVESCNDEVPDSGSELATPSSGSSGTVMPPSSMHNSNSQPGKLDGILYRTGCVLSQKDPHPDEHDVSTNVTTASSSSWPGEAPTQAHISVKTVSELSSTTHHYYNADSCGVGVNDTNSSSSTHNNGGGSNKDLMMDTASCQNDSDEDVIVDDDDTVKLTSKINYGKIQRRQDEQNVGSSRSLENISPVEERPRSEPQVSSTEPGPMDISHNNNNNNNNNNNNSNSNNNNNPSTKYAESMENSLSQLSSMGVPGLTQLDTKA", "length": 717, "molWeight": 76716, "crc64": "887D6033BD9FF679", "md5": "AC8F7632B19CB14711794989121A034B"}}
{"primaryAccession": "Q9XIA7", "text": "This is Mitochondrial import receptor subunit TOM6 homolog protein, from Mouse-ear cress, contains 54 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XIA7", "organism_name": "Mouse-ear cress", "protein_name": "Mitochondrial import receptor subunit TOM6 homolog", "length": 54, "firstPublicDate": "2004-04-26", "FUNCTION": "A component of the complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the Tom6 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFPGMFMRKPDKAEALKQLRTHVALFGSWVVIIRAAPYVLSYFSDSKDELKIDF", "length": 54, "molWeight": 6265, "crc64": "827D4D5609969B66", "md5": "9AE528875253592BFE2CD4783073E24E"}}
{"primaryAccession": "Q9XIP8", "text": "This is Protein CDI protein, from Mouse-ear cress, contains 259 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9XIP8", "organism_name": "Mouse-ear cress", "protein_name": "Protein CDI", "length": 259, "firstPublicDate": "2015-02-04", "FUNCTION": "Probable nucleotide-diphospho-sugar transferase required for pollen germination and tube growth", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTISNGDVKSETCNNGSSEKKPFRIFVGYDPREDLAYQVCHHSITKRSSIPVEITPIIQSDLRKKGLYWRERGQLESTEFSFSRFLTPHLSDYQGWAMFVDCDFLYLADIKELTDLIDDKYAIMCVQHDYTPKETTKMDGAVQTVYPRKNWSSMVLYNCGHPKNKTLSPEIVNTQTGAFLHRFQWLEDEEIGSIPFVWNFLEGHNRVVEKDPTTQPKAVHYTRGGPWFDAWKDCEFADLWLNEMEEYNKENKKEADNAK", "length": 259, "molWeight": 30216, "crc64": "E9069E4C67525345", "md5": "73F0703CF174A23FAAF0C4AB2C2BE867"}}
{"primaryAccession": "Q9Y6X4", "text": "This is Soluble lamin-associated protein of 75 kDa protein, from Human, contains 670 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y6X4", "organism_name": "Human", "protein_name": "Soluble lamin-associated protein of 75 kDa", "length": 670, "firstPublicDate": "2008-02-26", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the FAM169 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFPVDMLENCSHEELENSAEDYMSDLRCGDPENPECFSLLNITIPISLSNVGFVPLYGGDQTQKILALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVSTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSICASFLTQSYQLPVLDTMFLRKKYRGKDFGLHMLEDFVDSFTEDALGLRYPLSSLMYTACKQYFEKYPGDHELLWEVEGVGHWYQRIPVTRALQREALKILALSQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKAKLT", "length": 670, "molWeight": 74955, "crc64": "735D8883DA82C3F2", "md5": "BFF49F9241658BE2DEBEAB3053D358A1"}}
{"primaryAccession": "Q9Y7I8", "text": "This is Zuotin protein, from Fission yeast, contains 442 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y7I8", "organism_name": "Fission yeast", "protein_name": "Zuotin", "length": 442, "firstPublicDate": "2003-05-23", "FUNCTION": "Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state, RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain (By similarity)", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSAGDSIQLFPPTTKQAIEASFVPHGKISPLIKRAVEPVGPLFLAHARRQRHGRTFSEDERLEVKNKVQEEVKEESEDEEEDPAMLRADPKEWKQQDHYAVLGLSKYRYKADTEQIKKAHLKKVLKHHPDKKAASGNINDDSFFKCIQKAYEILSDPVRRRQFDSVDENADVEPPESTTKETFFELWTPVFESEARFSKKQPVPSLGTIESTRAEVDNFYNFWYNFDSWRSFEYLDKDIPDDGESRDNKRFQEKKNRSERQKNKARDNARLRNLVDTALASDPRIKLFKEQEKAAKAARKWEREAGAREAAAAAQKKKEEEERRAAEEAAAKASAAAANKKAKEDKKKAQKRDKKVVKNALKDFNYFSATDVPSAEHVDSVLKDVDVIMSKLGEGELGQLAADINAEKAAGAASVQAVFDKFAKMFIERGSMSSADVVFFAQ", "length": 442, "molWeight": 50209, "crc64": "F4EC924871B7318B", "md5": "258B9242BD721B4D39BC9C64C32184A4"}}
{"primaryAccession": "Q9Y7V0", "text": "This is Meiotically up-regulated gene 117 protein protein, from Fission yeast, contains 186 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y7V0", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 117 protein", "length": 186, "firstPublicDate": "2004-07-19", "FUNCTION": "Required for correct meiotic chromosome segregation, Appears to also have role in sporulation", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MWKFCCVTEKLTLFLFIYGICIYICIAVPIRSDLSTVFEPEAKGSRITSNYRRSLFNMLGYDNSVHPNNCKGSFLCPMLRGENRACPNAYMKYNRSLIYHGYSSYTASSCTAIYECEGDYPARTGNEIIDEFDQLNLQCSACGTRFFNNDNENTRCYVKLNYCYPDCTEITPSTSEYDYREPVRDW", "length": 186, "molWeight": 21551, "crc64": "878272EAEBD327DE", "md5": "FDDB563C0A39D0FFC77F306A317F29C6"}}
{"primaryAccession": "Q9Y7X6", "text": "This is Stress response protein ish1 protein, from Fission yeast, contains 684 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y7X6", "organism_name": "Fission yeast", "protein_name": "Stress response protein ish1", "length": 684, "firstPublicDate": "2002-12-13", "FUNCTION": "Has a role in maintaining cell viability during stationary phase induced by stress response, Activated by the spc1 MAPK pathway", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRSRSVASLGVLLAIVFYIFTYGFSTYRKNDTSAVKTWLEEHSIPYGSRSSPSDFQQFISESYDSLVPNLDKWSGHNLNSWLGKKTESSYLDAISNKIRKTGRKLSGSVEDARDATQEAWESQKASLFESWSDSQLRAFLARHSPQFAAKEKKGILEKLSPASLRETAAKEYDALTSKLGNTGDWIYDTWSDNELRTWLHDVGVPISSHESTRSHLLRKLKNYISTKADEAQPSVEAVKGKASEKAKQAGEFVSDKAGDAKELVNEKSSEAGQYAGQKMEEGGELLQEISKRRGRFGNWWANSGLKAYFDAHGIPAYQPSPIDQFYAHLRRQYYLKTNGYQALKSKAYEEASNVADSASSIASNVASGATEAYQGAASGASRFTEGAKTAAESVTSAFEHNKDTATSKAKQMKGKAASLGSTASEKVGEAADYAAETASKVASKAASKVRETIDETIIERWQDSKLKEFLFLRGVPVPQRSTKDQLLDLVRKHFNKGAVPNWAAYFDTLSSKELSAWIKEYKKHYHGKLHPSKDREHLFQNACNIYRAIAEKADKSVLQSIQSKFPKATVPGYDSWSNEDLKSALKEYGDSIGKVFNRKDAIERLKRHDILFYGPVVADKAKSGVSGFLRRVASFMGFGTRDVAEIKLGENIQKVKDTASKASSAVSSAGDYVETNVKKAQRVL", "length": 684, "molWeight": 75699, "crc64": "884CE69714BC7FAB", "md5": "89129907B984461FB232273D303F15F9"}}
{"primaryAccession": "Q9Y7Y9", "text": "This is Uncharacterized membrane protein C18A7.02c protein, from Fission yeast, contains 457 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y7Y9", "organism_name": "Fission yeast", "protein_name": "Uncharacterized membrane protein C18A7.02c", "length": 457, "firstPublicDate": "2008-06-10", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the LU7TM family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKLLISLLWSIFFSIVYSEKTLLNFKHYELCNGIYSKSESGGSLNPAIYVNWTEPWGQEDEVEVLIFNWKEIRKLGAFRSDDQFTYICDYDAVYTDHLCEADQLGLYLWNSTSAKSIRSYIIPTNADPQNIIYEISQSGYYCIWSHSKKMLPYQALVNWQNAYGGLPASQFPRMPISGGITIAYSVILALWMFFRFQYKHSIVTVQKAIMFLLIFSCAQQAVTSIVLDTENLRNRGNFTWLGETLVSILFACQLVLDLALLLILSWGYTRYSTNMRDRLFTEAKIPLIICFFALFVVRFFAITIQSIHLGLWFCFFFLTACISALYILFGAFVALPSTLRALVEQRYYTLHSIYKIFRIMVLCGVVTIFSFSLVALIFCSNTNNNSTNKLWKIRWYFLDGWIDGVHLTYLITLSSLWRPSQENPDLDPTGLSYPVLDPRLEEELDLLEEDIRADKSK", "length": 457, "molWeight": 52862, "crc64": "61257C6884669FB7", "md5": "5FB63FF67AE5EC09BE97B24E8EB1F8C3"}}
{"primaryAccession": "Q9Y7Z9", "text": "This is Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial protein, from Fission yeast, contains 479 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y7Z9", "organism_name": "Fission yeast", "protein_name": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "length": 479, "firstPublicDate": "2000-12-01", "FUNCTION": "FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis, Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid, The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the UbiH/COQ6 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSSLVLRGVSRVEMPTISPTLGIYTRKFASQKILQRQFDVVIVGSGPVGLALAAGLQSNPVTQSLKVGLLDIQDTMKLKDWKFETYSNRCSSLTNHTRMFFDKIGAWDFARKDRIQPFQHILASDGLTNSSIHLDQKPGSEPMAFMSENVNLQYALLNSIIDKMNNNIKKPNLEFLMPCTITKLSKGENIYRTHIHTTTHGELTTKLLIGADGRNSIVRKYANISMPGWNYLTHAVVGTLKIDPLKGPAVAFQRFLPTGPLAYLPLPDNNATFVWSTRPHIASKLLRLPEETFVKFLNASFRLDYPDLSYLYQMDFSEPSKVNEQLDWRLQVKRNSNMQVPPVITEIVSGSRAAFPLRLAHVDEYVKEGIALCGDAAHNTHPLAGQGLNTGIQDVESLISALSFAIKHGQDIGSVFSLQPYFRDRYFKNHVYLGVVDKFHKLYAMENPVVTSVRTLGLSLFDRSASLKNFILSTVANGI", "length": 479, "molWeight": 53575, "crc64": "83E22D10046F8A66", "md5": "6F38717993308C488C80F0A4679C7CAB"}}
{"primaryAccession": "Q9Y809", "text": "This is N-terminal acetyltransferase B complex subunit arm1 protein, from Fission yeast, contains 811 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y809", "organism_name": "Fission yeast", "protein_name": "N-terminal acetyltransferase B complex subunit arm1", "length": 811, "firstPublicDate": "2008-11-04", "FUNCTION": "Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the MDM20/NAA25 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRRSGSKESTIVYSALSLAQAGRGPEALALLEPLKSTPINSLELLDIIQAVYDDQKKGEESFVFWEKFLQTYGKQEKNLLAYFKASIRIKSLSHQRKAAVELQKNFPSRKHTLWVISSLYLLSKKSENEVEQRLLKALAEKTAKLIFEKPTGYIDSCEEFHLYLDVLLLVGDKDRALDALIHQDADRFVDADADLLLRKLELLASCARWDSLFTFSLSLFQTGNTDWKVCKALLDSASNDDSKLVPLKDCILKALSTSSTKRNLHLLWIEASARFFPEEHESALLGYIKKLYMKPIVFEDLRPYLLKLNVDAQHRLLDAFKLADLGESNESQKVDKLYAEVLLLKIHFLLFESFTAESVVDYVRRCFVAFEKGLSLSKGLLPTDFTHGYEALLLAVHSLIYMWEGNKDLKPAEKQALIFDAICLLEKGITYSQHNFHLKLPLIRLYLLLDGGFPAAAKVYDTMSIKQIQNDTLDHYLLTRATTYYPSSVTSHYINSSLKIYGSNEFETPEMISMAYEDGAYSQIEDMRNFRSRLDHSTWKSISLVERARIHYLTAFKPPKQYLPKCSSPKDNRDLKVFADYGSDKLPTVEESLRNSPKPDTLWIHLTVIGHSLVQDSIVNGDFEKAVLSAKEMEVLCENNDLSKQLTSEEIVHMKLLIQLGLLSVKVKNGDYENSSFETIENLIESFDYENSTPLSQLTKYTEIINDLITCLNSFLYHVSATKKKEFTRQYQLLKNISSNKLGSISGITKHKKKAARKYVSELLSNSWLSNLSETQVPYDPKFAKQVGEGMIDSYIQTTDAVSKLPKFVKF", "length": 811, "molWeight": 92457, "crc64": "F13CE125B60F4212", "md5": "8F278FBD1E492EBEF4745F4E26FB91D0"}}
{"primaryAccession": "Q9ZQX4", "text": "This is V-type proton ATPase subunit F protein, from Mouse-ear cress, contains 128 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ZQX4", "organism_name": "Mouse-ear cress", "protein_name": "V-type proton ATPase subunit F", "length": 128, "firstPublicDate": "2001-01-24", "FUNCTION": "Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function, V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity)", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the V-ATPase F subunit family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAGRATIPARNSALIAMIADEDTVVGFLMAGVGNVDIRRKTNYLIVDSKTTVRQIEDAFKEFSARDDIAIILLSQYIANMIRFLVDSYNKPVPAILEIPSKDHPYDPAHDSVLSRVKYLFSAESVSQR", "length": 128, "molWeight": 14259, "crc64": "A6B27BDA054FDA8A", "md5": "A7252ACCCECCD67DA5C55249BF351DE9"}}
{"primaryAccession": "Q9ZVT1", "text": "This is DUF724 domain-containing protein 1 protein, from Mouse-ear cress, contains 670 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9ZVT1", "organism_name": "Mouse-ear cress", "protein_name": "DUF724 domain-containing protein 1", "length": 670, "firstPublicDate": "2016-06-08", "FUNCTION": "May be involved in the polar growth of plant cells via transportation of RNAs", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAIFKDCEVEIFSEEDGFRNAWYRAILEETPTNPTSESKKLRFSYMTKSLNKEGSSSPPTVEQRFIRPVPPENLYNGVVFEEGTMVDADYKHRWRTGVVINKMENDSYLVLFDCPPDIIQFETKHLRAHLDWTGSEWVQPEVRELSKSMFSPGTLVEVSCVIDKVEVSWVTAMIVKEIEESGEKKFIVKVCNKHLSCRVDEAKPNMTVDSCCVRPRPPLFFVEEYDLRDCVEVFHGSSWRQGVVKGVHIEKQYTVTLEATKDKLVVKHSDLRPFKVWEDGVWHNGPQQKPVKESPSNAIKQKPMCSSSGARPMTPKMATKHARISFNPEENVEELSVAETVAATGKLEKMGIAEESVSCVTPLKQTEANAEGNKLEPMRNQNCLRNDSTQQMLPEEENSKDGSTKRKREEKHNSASSVMDEIDGTCNGSESEISNTGKSICNNDDVDDQPLSTELPYYQSLSVVNSFAADAEETPAKSARTISPFAKKLPFWKSYETDELYKSLPQSPHFSPLFKAKEDIREWSAVGMMVTFYCLLKEVKDLQLDDSSSKLSSLSSSLAELEKHGFNVTDPLSRISKVLPLQDKRAKKAEERKCLEKKIECEEIERKRFEEEFADFERIIIEKKRQALVAKEKKEAADKRIGEMKTCAETIDQEIKDEELEFQTTVSTPW", "length": 670, "molWeight": 76290, "crc64": "7022A17E1CDCD90A", "md5": "2B095968E75DDFF132C7FD14DBC5606C"}}
{"primaryAccession": "A2AVQ5", "text": "This is Lymphocyte expansion molecule protein, from Mouse, contains 414 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "A2AVQ5", "organism_name": "Mouse", "protein_name": "Lymphocyte expansion molecule", "length": 414, "firstPublicDate": "2007-08-21", "domain_description": {}, "SUBCELLULAR LOCATION": "Mitochondrion", "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRPRTHGAPPRNIMSTIPKWFKGAPFGVQSHRFDVSAVYPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKDTCFSKKFLEQKLGSGWSQAHEATRLTQLPHFHYQAIKKEKEQQVHKRGPGSYNIKDFITELQKKPQSKRGLLSSGETRFRGFIGNYYPGPGNYGEKGNPYTQLEEKAWNRSHSDGLMCRVSNKPPLFHQGSGLGPGTYTIKSDLETFVKKSTGNRGPYDIFSGERSSPLPYGHYSVQKMKPKELTDYKSFLDEMNSQHKKKQGVFSKYPRDPKHPTERIFWTTLSQCPKNMDIAGPGSWLPHETEQKHVNRPPFLLASKRCGLKAYQMILGTWNPVGVGRYLNTTLMESIDRRQRYRSLYMSEPKRYLQDLTRDRLMQKRITPITKGKCRPTVDYNSDPTP", "length": 414, "molWeight": 47584, "crc64": "251EF0F88B6E80C3", "md5": "B554E3A8681225FC26C228D1BE0F7F8B"}}
{"primaryAccession": "B3A0P8", "text": "This is SCP domain-containing protein 2 protein, from Giant owl limpet, contains 318 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0P8", "organism_name": "Giant owl limpet", "protein_name": "SCP domain-containing protein 2", "length": 318, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNFRVVFLTVFLSVPFCCCQNVTELSGTSPNGSSLSGTNQNSEPQKGVINAGSTPSSGTLSIASLQAMLATLMMTNKQTVAAASKPTVTNTGSKQPTATGQPTLSQPRKQLILTNRRRNPRRWGRVFIDNKSNLCAFERQNFLNSFGLHDKLKKDIVENLNKIRKDVKAQNMNCLLWSEKLAAKAAKLVKECTYQNTNKAAITSMVYEKEIGDQLVGRSLSRWMDNKKYFSYGNDCRDTGGCQFSQIVWARSKIIGCAAERCSDMTNMVCLFEPKGNVRNELPYLTGNQCAQCSASRGSTPTCNKDKLCEWYFPRPKF", "length": 318, "molWeight": 35355, "crc64": "8927E10B762F5D1A", "md5": "560F1184357BB16348FABEC7193FE26F"}}
{"primaryAccession": "B3A0Q1", "text": "This is Proline-rich protein 1 protein, from Giant owl limpet, contains 203 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0Q1", "organism_name": "Giant owl limpet", "protein_name": "Proline-rich protein 1", "length": 203, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMKLGLYLTLLFLSVWTVSGEPFKCTNICGKGAIIIAGVAYCCPQGYKPMIRRKMEDAFMATDCDCLFMMPAGQGMYAQYPQAPNQGSFIVQQPPQAPAVAVAPAAATVQVVAPAPTVVAAPPAAPPPPPPVVKVAPPAPRLPTYKPMYQMIRQQPMRQQRTWYHRPAPTYAAPTKSTKPKHEFFKFLDDFLSKQGYRGGNRG", "length": 203, "molWeight": 22216, "crc64": "2DA6B430E6B68A15", "md5": "144A102BDFCB9568DBBDF8902909E003"}}
{"primaryAccession": "B3A0Q2", "text": "This is Glycine and tyrosine-rich protein protein, from Giant owl limpet, contains 296 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0Q2", "organism_name": "Giant owl limpet", "protein_name": "Glycine and tyrosine-rich protein", "length": 296, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKVLVTALIISFSTAVLTVPVSIITAPLSVETIPGSSLDSTKVLGKLEAAYAQYGADSTSFKNSLQNIINAYMSIAADYEAQAGILEVRADIAEAAKNDVLATELEIKGDALEALAEGYTKTAEMLQEFLKLISEHEHKLSVVFREVKSGMIGTAAMESRLRPQATSSLPATGGQPSTGGKPTTGGQPTTGGQPSTGGQPSTGGQPTTGGQSITGGQPTTGGQPTTGGLPTTGGQPSTGGQPTTGGQPTTGGQPSTGGQPSTGGHQQLGVNQPEETPAPNRQLKMFRHYSKVCWQI", "length": 296, "molWeight": 30295, "crc64": "9844538F0CF1D758", "md5": "7A94A8EBE134F88CF9ED348F3EF8CBA7"}}
{"primaryAccession": "B3A0Q9", "text": "This is Perlustrin-like protein protein, from Giant owl limpet, contains 121 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0Q9", "organism_name": "Giant owl limpet", "protein_name": "Perlustrin-like protein", "length": 121, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKFGVGFLLSCLVALNTVQNMLALSCLPCDFDTLKCSPLPDDDDCFPAYTPCGCCPQCAGEEDDFCDNFTVRCHPDLVCVNATGFEKKFVYWYEFDFKGTCQESELETEYEYEYEENETKK", "length": 121, "molWeight": 13822, "crc64": "0AED7454C6119438", "md5": "1F2B097575B6F897FBDE147D99315FEC"}}
{"primaryAccession": "B3A0R3", "text": "This is Uncharacterized shell protein 13 protein, from Giant owl limpet, contains 264 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0R3", "organism_name": "Giant owl limpet", "protein_name": "Uncharacterized shell protein 13", "length": 264, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMWNYFVTCIVLYANIISIHTFGLTGGNNLNQALGLTGGNPLDSTLGLSAGNAFPSGMGAMQIPAYLRMAPSVETICSTQSPLLNPRERNGLLSDLVGKEISRRSRFLAANPSLAGTGKWACAANYYSNVMRYRPNELGNVFGDLIDSTGCDGFTCDMVRGVRKTSPMSNFLNAMMISQMMQQPNAAQVPTTSQQQPTSNTGGQQPPTNASNPPTNPQPTPTPAQPTPSGTQVQQTPAANNGLDLTSMFNNPAFQEQLMRLVST", "length": 264, "molWeight": 28214, "crc64": "3823FE1F0811FDF2", "md5": "2258C96AB8186ED36762C2A4CACF65B3"}}
{"primaryAccession": "B3A0R5", "text": "This is Uncharacterized shell protein 16 protein, from Giant owl limpet, contains 214 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0R5", "organism_name": "Giant owl limpet", "protein_name": "Uncharacterized shell protein 16", "length": 214, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MWCFIVFLTIFLPTLEGQYGPAVTGPSLPEELCTKDPQVSRGRFYRLKVRPSFYRRAHPLQVELYQTIHAYGPIIADAYVHVPETAKNSSTAALGIKTLGYWLPKNPDNYKISRALSCYNSVWGNDAIVANSDRELKFNLTGIWYPPTSEFDLIKRPFVKIVAYVTPDPDVRRRRWYRAESQPIRNLDYIAFQHHMRRYKAQMKAFRTQLEMFN", "length": 214, "molWeight": 25000, "crc64": "B90C871C3D01133B", "md5": "6EA2ABE934DAA6C7BB2F68F1E452A011"}}
{"primaryAccession": "B3A0R6", "text": "This is EGF-like domain-containing protein 1 protein, from Giant owl limpet, contains 513 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0R6", "organism_name": "Giant owl limpet", "protein_name": "EGF-like domain-containing protein 1", "length": 513, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMHTFLRRLCVVALCLGYIKASADFDCRRTSQSCVTGTCNDVNGDCDCPTDANGVATHRNADCGLEIAKVVPTALCGPPCLNGGECYEPTVGTYMCMCPEAFYGNKCENPRKKVECSGTEITINYMPIPTFSGDIFILDNRNTPECAFTEANGMYTATFTYQQCGVTTTNDQPNAGDTSYEISAAVRFNANIERATDMKLTAKCVIDGTGQSNLNDNIGTVSVDQRTDLTEETALTEYQPVSFQLQGKNGNPMPVPVNLGDELRIYIPLADTGRYTKLKITELQTNNGMVEQDLVMETLIFNGCLTDIGEALVTGDISSDPAIPAIIINFMAFRLRGSPQVKFDARVQVCEGTDTSCDSVVCPSPPQSVPSNPQNIPPANPQNIPPANPQNIPPANPQISPSSSQRKRRAAPDNEVILHETLTVLDPRSNEKLRLPHNKSDIKSQQNADPQQCLQSTEIMVMVIVLIVAVVLLLVITTCLAVKFMKQRAAQVKIYNPDMPTGNNTVRIPRAAC", "length": 513, "molWeight": 55793, "crc64": "FD83B57487C34AB6", "md5": "6C9BFA7D2B8FE38EE349DBA79AF49839"}}
{"primaryAccession": "B3A0R9", "text": "This is EF-hand calcium-binding domain-containing protein 2 protein, from Giant owl limpet, contains 119 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0R9", "organism_name": "Giant owl limpet", "protein_name": "EF-hand calcium-binding domain-containing protein 2", "length": 119, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKVAVVLIVVLVVMMIGQETDSWRIRIRRGRKIFRKIRPYIPFVIGAVGKRQAGDAEFQAKYNAAAEDGVFTDEEIKSVFGVDDNGFVEFKATYDVDGDGVVQVEEYETVVELTENLAG", "length": 119, "molWeight": 13305, "crc64": "91CBC35AE14328B9", "md5": "9DA0907892B8ADFFCF5A9DBC4F180B8B"}}
{"primaryAccession": "B3A0S3", "text": "This is EGF-like domain-containing protein 2 protein, from Giant owl limpet, contains 489 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0S3", "organism_name": "Giant owl limpet", "protein_name": "EGF-like domain-containing protein 2", "length": 489, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMQTLLRGLCVVVLFWGYIKASADFDCRRTSQTCVTGTCDDVSGSCVCPTDAGGSPSHTNKDCGLELAKVASPATLCDPPCLNGGQCFEPTADTYMCMCSEAFYGSQCENPRKQVECSGDQITINYMPIPTFSGDIFILDNRNTPECAFTEANGMYTATFTYQQCGVITTNDQPNVGDTSYQTSAAVRFNANIERGTDMKLTAECVIDGSGQSNLNNNIGTVSVDQRSNLTEETALTQYQPVSFQLQGKNGNPMPVPVNLGDELRIYIPLADTGKYTKLKITDLTTNNGMAAPDMVTETLIFNGCLTDIGEALVTGDISSDPAIPAIIINFMAFRLRGSPQVKFEAKVKVCEAADTSCEPGSCPTPAPPAPVQPTPSENPGRKRRAASDNEVILHETLTVLDPRSNEKLRLPHNKSDKKSQQNADPQQCLQSTEIMVMVIVLIVAVVLLLVITTCLAVKFMKQRAAQVKIYNSDMPTGNNTVRIPHSAF", "length": 489, "molWeight": 52888, "crc64": "8F73E6AA1E7AB8FB", "md5": "B6D69C621C7E791D96FE0ECF13FDDBD8"}}
{"primaryAccession": "B3A0S4", "text": "This is Proline-rich protein 3 protein, from Giant owl limpet, contains 195 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0S4", "organism_name": "Giant owl limpet", "protein_name": "Proline-rich protein 3", "length": 195, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKMNFFNSFPQYGVYILGLNLLLCGVSEGFIGFGMDGFEEMFPLLMLGGMNGGQSNYVRPKPIAPTLPPTPPPPMVKPPSITWRWVPNTRYTWPLFNNMQWPQYNPYVLPLANNAMAKTGSAFNTNTISGTKASSGNAMPVLPAPNAQMISSGGPVPPAAGLMNGMGMGLAGSNMAAANQMTWNTQTTSKGSTPM", "length": 195, "molWeight": 20857, "crc64": "0C7A8361364A35D0", "md5": "9CCBD08D5869BADBAB301D00518B7828"}}
{"primaryAccession": "D2CZZ9", "text": "This is BURP domain-containing protein BNM2C protein, from Rape, contains 281 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D2CZZ9", "organism_name": "Rape", "protein_name": "BURP domain-containing protein BNM2C", "length": 281, "firstPublicDate": "2016-02-17", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASLRFSVTFPALFSLLLSLWVVDACTSRKLISNNEQEGQNISHLFKDGEFEDPTMYMFFKISDLKLGTKLPIYFNKNDLRKVPPLLTRQEADLIPFSESNLDFLLNHFSISKDSPQGEAMKETLQRCDFKAIEGEYKFCGTSLESMLDLAKKTIASNADLKVMTTKVMVPDQNRISYALHNYTFAEVPKELDGIKVLGCHRMPYPYVVYYCHGHKSGTKVFEVNLMSDDGIQLVVGPAVCHMDTSMWNADHVAFKVLKIEPRSAPVCHFFPLDNIVWVSK", "length": 281, "molWeight": 31937, "crc64": "B3EE8A788CB7DC16", "md5": "B567D3840F8D44BAADC5C1F58AB44050"}}
{"primaryAccession": "D4AK17", "text": "This is PI-PLC X domain-containing protein 1 protein, from Trichophyton mentagrophytes, contains 305 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4AK17", "organism_name": "Trichophyton mentagrophytes", "protein_name": "PI-PLC X domain-containing protein 1", "length": 305, "firstPublicDate": "2016-01-20", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSMSTLRHFLWLGALLLATIQVSALPTAQDLICNGHPEYCDRRYSELSFVGAHNSPFVGPLLQHNQDISVTEQLDFGIRFLQGQTHKNDDGVFSMCHTSCILEDAGSVSSYLQTVKTWLDSHPNEVVTLLITNGDGLDIKEFDDAFNAVNGIKDYTFAPKSKLALGDWPTLRELITTGKRLIVFVDSKADTNRFPYLLDEFSYYFETPFSTTDENFPQCKLDRPAGGKPDGQMYLVNHTLNVNVFGIFLPDRFKAGRTNAAVGQGSIGAQVDLCNSIYHRKPNVVLLDFITEGDVLKAERTMNGL", "length": 305, "molWeight": 33966, "crc64": "2A729CB34DA308B8", "md5": "7B8D3E83865135A59F1B54C627B7BCD4"}}
{"primaryAccession": "D4AL26", "text": "This is Fucose-specific lectin protein, from Trichophyton mentagrophytes, contains 365 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4AL26", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Fucose-specific lectin", "length": 365, "firstPublicDate": "2015-11-11", "FUNCTION": "Probable L-fucose-binding lectin", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the fungal fucose-specific lectin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLLHFTILLQVSLFPASSLAQAGGNNTEVQVQQTLPGTGIAAVNSVNLLRIYSQDTSGGIREARFEGYWSGGLANDTIAKARANSSIAAASDDLELYKSSSSTNFLLKIRVYYLLPNNTLGEAASDSQSRWYTGSLNQYNFQVASHSRLAAVFVPSTQRPRLRIYAQLGDNTIQEFGYDVSPLSQLEPMFANYLKVGRGWQRLANFGPALPGTGIAALTYTTGLRRSTTRVYFQTTDRRVVERVYDNRSWSDGGTVVRTAKPRTPLAATSFLLTPGNPQSVRVYYGTEDNRILEKGTEGGTYWYDGAFEHSAIPDSQVAAVDWGNGGVFNIRLYIQDGAFKNGISEWAWFRRSWRRGILAIPPA", "length": 365, "molWeight": 40297, "crc64": "CCDD3526FCA39D3F", "md5": "40C3BC6F3BB79F546E1749B0E1F7E096"}}
{"primaryAccession": "D4AR77", "text": "This is Uncharacterized secreted protein ARB_06907 protein, from Trichophyton mentagrophytes, contains 930 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4AR77", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Uncharacterized secreted protein ARB_06907", "length": 930, "firstPublicDate": "2016-01-20", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPSFVLWTFHLCSQWFQGLTDLLPHIPDTQTVNNFASQTGLLYPGGMKYSKIASWVCIPLLTCRGVDATNSADGGSELQLNESPFSKNWQVLGPFEIGTRESSWGADPLEAYGGFQTLQYDPKASFDSSLALNGLANWSMASTHVNSTANPPETILDINLSPDNLTSLQEVYGWDAKQYQAWARGTLTVSKSNSVVALYTDRIWEYRIDNKSYFGGDFFGFRRAPLLLDLSPGTHTVDLRVVRDVRALGAVGEPFINVTLIAQELSKTLIVDKKSILVADVVENRLISPHASVTLHNTMGNPVDVAARFSLKMLNNNVKLEEAQSRAIGFTIEAKDKINVPSSVSLYFEYTTPDDSSVQRTQTMTITFTRRKLPEVQQNTFMLPGGVVSYATMRPPTSLECNKDKSAKLPVLLGLHGAGQAASDEIIRTMLDGVSDICAWTLFPSGVTPWSGDDWHTWGFADLQHSVRALNDYIKYSGWTGVGLIDGDWIIAGHSNGGQGTWYTISHYPDKIIAAAPVAGYTSIENYVPYSMWHNTDSLLASTFYRARQDFKHEILVDNFAGIPVYQQHGASDDNVVVYHSRLMHRLLQESGSPSKYHEVPGKNHWYTGIMTSDFLKDFYRTYVQRPNATDLLPQRFSVTLPPAGHMGTRGGIYVDQSHTPDRVGSIEVERGMANDGVWKLKTRNIRRFHLETSAIRSHVPLYIQIDGSRFTVTPSNSTTTWYTQDAAGKWTSGGDSWRTISQRYGRQAGVNAFLRTEAPFTVTAAAQETRDLALQTCRNLFQYLSADCIISYAVPTANSTTATSPAGNNVVILLGAQPNGYTAGDSAISISARSLDIKTSQGTTSYPFEPGLGAIFIRPLVNERLELVIWGSDMAGLQQAARLVPVLTGVGQPDFVVVNKGTPLKGQGSLYAAGFFDSEWKVSAASYVS", "length": 930, "molWeight": 102354, "crc64": "8900C1FE0E8E06B2", "md5": "DE92B1F6F403386E02D1516BE5AD989A"}}
{"primaryAccession": "D4ATH2", "text": "This is Probable secreted aspartic protease ARB_07536 protein, from Trichophyton mentagrophytes, contains 417 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4ATH2", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Probable secreted aspartic protease ARB_07536", "length": 417, "firstPublicDate": "2015-11-11", "FUNCTION": "Probable secreted aspartic protease that supplies the fungus with nutrient amino acids (By similarity), May be able to degrade the selected host's proteins involved in the immune defense (By similarity)", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the peptidase A1 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGILILVALGAATIPQASAAPNDRQQSMIDLPLKLYQNGFNTDLVTIGTPAQATRLFVDWTWIGAYTVSTKCNHTNNAYGCLAPGQKLFNETQSTSLVNQTNLYPTRTWNPNHFFMDKDLTAVFASDIYRVGDRESRLTLQLSQLNWKASFPYPFSGIFGMSPVFKSDNMSIQAPFHQMVQQKKFHSGLTSFIYCYSDEPGYKSPSKERCNGNDGIQTLGGYHHRDIGWRGIEWINTIVFPIVNDIDFIYNPAFYNYWSIPVTKHFIGNEEQALNTTTGSAVVFDHASYGRGAAMSVASYRRLVSITNAQPVNLTMATLPNNGKQKFYSVDCDRVDSFPAVKYQFGKWRRVWSIEARHYISKAKTMDGKDVCVLNVRVIGQGENFVIGNLGENFAKDKVILFDFEKNRVGLADFRD", "length": 417, "molWeight": 47034, "crc64": "74672B015119BACF", "md5": "B69003A4F80A0C8B3D8BD48D01966B6E"}}
{"primaryAccession": "D4AUX6", "text": "This is Uncharacterized secreted protein ARB_08043 protein, from Trichophyton mentagrophytes, contains 442 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4AUX6", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Uncharacterized secreted protein ARB_08043", "length": 442, "firstPublicDate": "2015-11-11", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEILLIVLGAVVAGLLCPVQTAAEATITLTGSDIPTSISIHHGTRTPTSSGELSQSTFSSSSTNSSDSFYTTTSASYTLLVGSHTTSTVTANETTLSGNATATETSREPQPTNTRPCNGYAEFCARSYGNITQVAAHNSPFVRPGNIASNQELDVVTQLNDGIRMLQFQTHLVNGTIYLCHSSCDLLNAGTLESYLKKVADWLRDNPYDVVSLLIGNGDFVGVKNFTAPIQSSGLIDHVYTPKNHSIALDDWPTLSEVILSGKRAMVFMDYEANHGEVPYILDEFTYIWETPFSPTDRNFPCDIQRPPGLNEADARKRMYMANHNLNLEISIAGATILVPNTVLLNETNAVSGFGSMGAMAGNCTEKWNRPPNFLLVDYYNIGNVNGSVFQVAAKLNNVTYNGKCCGRTTSLASESVLGRLSGKLEMIYSMIVINILVMTIL", "length": 442, "molWeight": 47857, "crc64": "605CF0683786F56E", "md5": "F615D0FE95C1994454433BAC3D4CE1CA"}}
{"primaryAccession": "D4B1Z7", "text": "This is Uncharacterized FAD-linked oxidoreductase ARB_02478 protein, from Trichophyton mentagrophytes, contains 565 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4B1Z7", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Uncharacterized FAD-linked oxidoreductase ARB_02478", "length": 565, "firstPublicDate": "2015-11-11", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the oxygen-dependent FAD-linked oxidoreductase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKIPSQQVLLALPLLASPAQSYPGKHPRCSAGDACWPKEHVWQDFNSTISGRLIRTFPAAAVCHTAQYDAAACSVAKERWTDSFWRTNQTGAYSAILWELGEKGQCFINTPKEDRCDQGIVPYYSVSASGVKDIEKAVKFADKHDLYLVVKNTGHDHLGRSSGSGAFSIWTHNLKGKEWHKSFKPKGAPSNVSGIPAVTLQAGEQLLDVYKAAAAEGVTFAGGSAQTVGAAGGFMTGGGVSPFSHFYGLAVDNVLEVNLVTAQGKAKTINQYTDPDYFYALRGGGGSAWGVITSVTYKTHPKPTHIRVGIAQLNITTEDSRRVVIEKTLQALPDITEAGWVGYGVYATEKSNPTAFQVIFLQPNATMENFNKTFEPMNEIATLPGVTGGAVSYVFPDFLEYSKNFLRDPNIATNVIDASRLVSRQVLTERARDLVDLMFEYPTTGPGFNSIVKVNSDERDNTAVHSSFKNSRALISFSVDWADNASEKEKKAAKKTSAEVSKRLAEIVGKETGTYLNEASPYEPDWQNAFWGDKYARLLSIKRRIDPKNLFVCNRCVGTDIILEP", "length": 565, "molWeight": 61795, "crc64": "9C3FAFBEAE627E86", "md5": "BB060BCC0CD2816D077DFF9ABA2DAECE"}}
{"primaryAccession": "H2A0L9", "text": "This is Serine, glycine, tyrosine and glutamine-rich protein protein, from Freshwater pearl mussel, contains 332 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "H2A0L9", "organism_name": "Freshwater pearl mussel", "protein_name": "Serine, glycine, tyrosine and glutamine-rich protein", "length": 332, "firstPublicDate": "2012-06-13", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MMKTVLLLVVLVGVAYCDDDGWDMGNFFQQYHQWQQQISSSSSSSSSSGGGGSSGGGASGGGGGGGSSGGGGASGGGGGGSSGGGGLTKVVLKAGGGGRGGGGIVKSVGGGGGGVTKLVAAGGASGGGSVSGGGGGGLALLAGGSAAGGGRSGVVTVSKQPIIINRQVTHVNTGGSGGGVGGGFGGGRGGFGYGLYGGHHHYNPCGYGQVYSYYYGCQSIYKQPARQVYHQPIYQPVQTVYQPVQYYQQPYQYQHSYGQASHAYQPQTTKYISYSYPQYSSQGSYPIVAGGSAGGFASARSGGFGLSSGGIGGHSSYPLSVFKHAKGEKYKL", "length": 332, "molWeight": 32498, "crc64": "700C424052262BC5", "md5": "2B35E6A5952959F1C469BB14CC661283"}}
{"primaryAccession": "K0P7H2", "text": "This is Upsalin protein, from Painter's mussel, contains 125 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "K0P7H2", "organism_name": "Painter's mussel", "protein_name": "Upsalin", "length": 125, "firstPublicDate": "2014-07-09", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFPTHVLLIVIACVTAFVYGGGGKRPRVCRYSSDGPVCRTNIECSDPEVHCYRKPGHPYGRCCVKRPYACPRGSSNRYDDPEGFPPLVQRCPYAYPFFCRPGYYCRTKTGGSTEFYGVCCPLRVG", "length": 125, "molWeight": 14007, "crc64": "C55468C0CE20C0C1", "md5": "FD66C6F3AE796CF0A46ED2B22E7A54D2"}}
{"primaryAccession": "O13472", "text": "This is Protein SPT3 protein, from Yeast, contains 328 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13472", "organism_name": "Yeast", "protein_name": "Protein SPT3", "length": 328, "firstPublicDate": "1998-07-15", "FUNCTION": "SPT factors 3, 7 and 8 are required for the initiation of Ty transcription from the delta promoter, SPT3 regulates Ty1 as well as the mating factor genes, Interacts directly with TATA-binding protein, It is likely to be required for normal TBP function at a subset of RNA polymerase II-dependent promoters", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the SPT3 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSDKYKYRVEIQQMMFVSGENNEPPVETTSLIEDIVRGQVVEILLQATRTANCRGSKSIVPEDVIFLIRHDKAKVNRLRTYLSWKDLRKNAKDQDAQQAAAGGGAGDGSGPGGIDDDDAGKKDKDGAGVNMKVKKSSIKLPWELQFMFNEQPLENPDEDDMDDDEREANMATLKRLKMADDRTRGMTKEEYVHWSDCRQASFTFRKSKRFKDWSGISQLIDSKPHDDVIDILGFLTFEIVCAITETALKIKTRYERIRSMKTQSQPQEYSVGTTRRKKRLFDGPDNVVNPLKPEHIEEAWRVLQTVNMKHRALSNYKGGRLSSRTVIM", "length": 328, "molWeight": 37452, "crc64": "38989ACD10F47940", "md5": "3D8EDAA99BAF6B0AC25B7AE621562DC6"}}
{"primaryAccession": "O13660", "text": "This is Uncharacterized mitochondrial carrier C27B12.09c protein, from Fission yeast, contains 277 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13660", "organism_name": "Fission yeast", "protein_name": "Uncharacterized mitochondrial carrier C27B12.09c", "length": 277, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrial carrier (TC 2,A,29) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDQAIAGLAAGTASTLIMHPLDLAKIQMQASMNQDSKSLFQVFKSNIGSNGSIRSLYHGLSINVLGSAASWGAYFCIYDFSKRVVMSMTPFNNGEISVLQTLCSSGFAGCIVAALTNPIWVVKSRILSKRVNYTNPFFGFYDLIKNEGLRGCYAGFAPSLLGVSQGALQFMAYEKLKLWKQRRPTSLDYIFMSAASKVFAAVNMYPLLVIRTRLQVMRSPHRSIMNLVLQTWRLQGILGFYKGFLPHLLRVVPQTCITFLVYEQVGMHFKTQSSKSQ", "length": 277, "molWeight": 30858, "crc64": "F59957CBB7A2EDE5", "md5": "338D110F9FD5A88D2DEBDCA3212D876A"}}
{"primaryAccession": "O13674", "text": "This is Meiotically up-regulated gene 24 protein protein, from Fission yeast, contains 654 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13674", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 24 protein", "length": 654, "firstPublicDate": "1998-12-15", "FUNCTION": "Has a role in meiosis", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAIMHKIGCAGSEVETDRVLEKDQANNGHFVDSDCCFQETGSTGTANSICTLNDSEDDNSSLNSVDNNECTNLDCGGKKHKNLSPNPSFHVNINAAEFIPKSHNGYAPKSMNPPPEQLDSPCYPHFDQDSSSVIYPSPPSTYYPNMYVSANTFIPMPYAHYTDNMYHAKPVNRPNFLPREGTPPPFAQQPAEQFSPFNSEYESLLDFRALILGNLPVDYKISELLSLIHSGPLEKIQSNPGKRRIIITFLDSADAFFFYERYHPRGFIFHGRPLKLTFARPSPLPESIQNFCSNTAASRNVFIGNLPSSYHEKEIEEAFGKFGKIEHIKILSKKNIAFVHFLNIRDAIKVVRTLSCDPDYHSWRIFFGSDRCANHPPSFDERSCFTSKQNPDTTSDRCRQQESKDNGNRTVFLGNLHTKTKGHEICDLIRHGGLQDFHYIPEKHICFVTFITYSAANAFHDYLAEEEVLLHGRRIKVGWGKESGPLPRVLEDSILMGASRNVYFSHISDSLTTEELELILRQYGEIESIKYLKNRSSGFVAYTNISNAMKAVNGLPIHPLFKKSKIRYAPDRCEQELQKSKSNSPIQQNVPLQQFITPPFSYPVAYCPAIPPGSDPILNFGIQYQPFIPFTAVPSFPFNCNVPNYPQTSDHEND", "length": 654, "molWeight": 73881, "crc64": "CEC410AEAE6853DF", "md5": "20D0E3B55DC6ACA19187E24576748FCB"}}
{"primaryAccession": "O13699", "text": "This is Meiotically up-regulated gene 132 protein protein, from Fission yeast, contains 430 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13699", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 132 protein", "length": 430, "firstPublicDate": "2004-03-29", "FUNCTION": "Has a role in meiosis", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the UPF0300 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLSFGGSLLSHSDIASRNKFSIDYSQFKAFFPGNWKFSNSKDKKPVRSPTLDEPVGDVDIDIFDVSKFYPLKRLSSIPEKIRANYHEELQTTSYDLVRNPFTHGLFCVVFYHQNKSYLKMGVTDNFNAFEEDSRVYQYGVNHKLSCKNLLLAINYSPKTYTKIFDFLRNGRAPLQVLVHHCMLYNFYPEDFQDALWCAVQAHVMNQVRLGRATLLHARACYQKIGDIRMYLIDPHDLYFSPNSLKWLIICSKQFQALVHLEVKMDTLKIFRRRSKYFNLARSCVSGFELSWLIMMTSIGSNASAVPVHAYLASKRILYPSIIPEEIFFMRKFDSSLFKDIKNIHELLGFLGRLFMDLQDCEKFHHDYTEYHCYRIGKPLYQNYEEEALRKKSQGVKDADFIKPLVTNTRTAEKYKAFFEYKRNIVLKKQS", "length": 430, "molWeight": 50433, "crc64": "6FE023D9545B286A", "md5": "D55C06A8C34BE5C7D30C531407B84349"}}
{"primaryAccession": "O13746", "text": "This is Uncharacterized protein C16E8.18 protein, from Fission yeast, contains 107 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13746", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C16E8.18", "length": 107, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEVTSFILNATFKEFACFGNNYLIILPGIMLERNVFRHLNYSTNSICSHYQFFGGHYESFELLVVIVYYFSHVGSFSLAEIYRITWDKRIVLYGTTTTLVYCSEGSD", "length": 107, "molWeight": 12425, "crc64": "C47FC7F6DF29B4A6", "md5": "F6210533FCDB94CA5B68F79C4DCA5FDB"}}
{"primaryAccession": "O13894", "text": "This is Meiotically up-regulated gene 103 protein protein, from Fission yeast, contains 124 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13894", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 103 protein", "length": 124, "firstPublicDate": "2004-07-19", "FUNCTION": "Has a role in meiosis", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEQFEIIRESDADPYYFNKNLRLEECEIDGFTSIYKAPPPYSFVAGLSKNTSSNSFVIHKCLPPLQRNNTIRKRKRNPFLADRPYCINSEDMPLSDDRDMLKERHVKSRKLLLKEKGNRFYRRS", "length": 124, "molWeight": 14736, "crc64": "C93DEAB43D03544A", "md5": "BBF847C36D9CC0D888550AB695184FB0"}}
{"primaryAccession": "O13904", "text": "This is Meiotically up-regulated gene 84 protein protein, from Fission yeast, contains 195 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13904", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 84 protein", "length": 195, "firstPublicDate": "2007-02-20", "FUNCTION": "Has a role in meiosis", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MTLTHHSTFIKGIEGSAEGEIEDVRQTTVFDPPFYGHPMLVPPSPSLTTMFRTRSTTPDEEGTAIAEIDQQDWDIMVKVPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIYIHVVLNAYNTEVLTKPFSSLECIVDQYALVGEEDGAAHGRVVDLRLCDVNKQQLEET", "length": 195, "molWeight": 22264, "crc64": "433102157861A229", "md5": "E14D351E56CB7EF6BCC2EE5DD4FB981E"}}
{"primaryAccession": "O13905", "text": "This is BSD domain-containing protein C22A12.14c protein, from Fission yeast, contains 347 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13905", "organism_name": "Fission yeast", "protein_name": "BSD domain-containing protein C22A12.14c", "length": 347, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDLYDYMAPTTTTEEDDEEGYEKLKEEMGSALNNLTNGKFGLFWNSMKEKSENFLDDTKGKASSGMQQLKSQLEENIPVNSAMENLRKVEETAGSFWSGFGSTVNGFLDQALQISPKEDDVSTPTHEASSSVFLNRHERQLLELVQNENTFTQIISEPSHGITFESWEKEISIDGKTEEISLLLEEYPDLRKQMESLVPSEVSYDDFWKRFFWHKEVVQPIKAIQSGNDEEEIFSWGDERSDEEESDNEQVNDEKKQSSEEDTTENNSAAEVIDETVNDLESAVSKGLQIETQPASHDGEVDGEVKEEEENKVSSSSNIEASQSSLEVKDEANRKVDDDDEDDDDWE", "length": 347, "molWeight": 39397, "crc64": "9BA13E7C14E423AC", "md5": "F34789A03C28807C4EE7B9BEE893885F"}}
{"primaryAccession": "O13970", "text": "This is Small ribosomal subunit protein uS2m protein, from Fission yeast, contains 263 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O13970", "organism_name": "Fission yeast", "protein_name": "Small ribosomal subunit protein uS2m", "length": 263, "firstPublicDate": "2007-11-13", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uS2 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLSRKLSPEQLVARRLKIRDWNHKIGAVVAPHYSPTLSIRNPAPPSQLSLPLLLSSGAHLGHSTSIWNPYTQPFIYGKREGIHIISLDQTMVYLRRAISVVRSIAKENGIILFIGTRNGQKDSVVAAAKRARGYHIFDRWLPGLLTNAREVQGKLGGSILCKDNRGKLIQTDKKPSYVFPDLMVILNPLENKSACLEAQKTHVPTIGIIDTDADPRMVTYPIPANDDSLRCTDLIAGLLSRVAEQEYQKANQAFEKDKFTLPL", "length": 263, "molWeight": 29311, "crc64": "D646EB2A5BAB276C", "md5": "4F4A6330C7F05697865CDB93CB1CF106"}}
{"primaryAccession": "O14038", "text": "This is Uncharacterized protein C2C4.05 protein, from Fission yeast, contains 134 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14038", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C2C4.05", "length": 134, "firstPublicDate": "2000-05-30", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the cornichon family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVSAWIYFTSLMLTCANIMLQMYFTVMYSDLKDDFINPIDLSRKLNWYVLPEMGFQAFSALLLLLSGAWITFLLNVPMLAWNAKMIMSNTHMHDSTTIFKDVSSRQKRSFFKLACFAVFFFVYLFLFVSRLVDE", "length": 134, "molWeight": 15738, "crc64": "71E58F624E87F523", "md5": "47D8611250A36603D94EF62A2E932307"}}
{"primaryAccession": "O14097", "text": "This is WW domain-containing protein C2F3.14c protein, from Fission yeast, contains 331 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14097", "organism_name": "Fission yeast", "protein_name": "WW domain-containing protein C2F3.14c", "length": 331, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSSSKDCKATSNVDQTIPASNVNSGDFISSNTSSSNSENSNIQGKHYTQVGEDADNSFISENTPKNTFESTQTYENLESISKNEPTSEASKPLLNELVPEEPLPREPPLPNEPVPEEPLPGEPPLPDEPVPEEPLPGEPPLPNEPVPETNCHKESPLSDETVSETSKNDTSNSPTNENQAQPSIAWSEGHRIAAIWDPSQQAYYFWDTLTNTTSWNNPLEDEEQTSPLDYTAKVQFNRLSGKFMPKWASPELRSEENKAHKHMEQYFDINSSLNSHNGQSLLAERRNKRYTRKEMEQMKRRTKEKKEMKRRALYDIASDEKDFRRRKIIRY", "length": 331, "molWeight": 37669, "crc64": "EA888EACC4CBB7B1", "md5": "96AE5C57D81F5351952132C5D59577D0"}}
{"primaryAccession": "O14119", "text": "This is Seipin homolog protein, from Fission yeast, contains 249 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14119", "organism_name": "Fission yeast", "protein_name": "Seipin homolog", "length": 249, "firstPublicDate": "2008-06-10", "FUNCTION": "Involved in lipid metabolism and lipid droplet (LD) morphology, number, and size, Facilitates initiation of LD formation, and ensures that vectorial budding of LDs from the ER is directed towards the cytoplasm", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the seipin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGYLVKLFKLVVWMLVIGLFSIPSLVSYVIFYDTVIPHSVIQYPVYFNYTTGLNFPTAEVRLDHFSIDPRLPGTSLLQIKMPHSPRNSAMGNFMVSVDFQDRNQRSLKQVKRTVLLPHRSPIHEYLKLIVCSPLYFMGILEETDIVNVRLFESETFAKSFNSITTLSVRFSVKNTPAQAIVKIYSKDIEFYEATLAFASKLHGMRWFMYTHKVSAFLVFTSLFWFTGITSTIITYLIVSSTSETKATRR", "length": 249, "molWeight": 28673, "crc64": "0CB0BE795BB14236", "md5": "4E4A957397FD7C06FF672DA981415204"}}
{"primaryAccession": "O14158", "text": "This is AB hydrolase superfamily protein C4A8.06c protein, from Fission yeast, contains 578 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14158", "organism_name": "Fission yeast", "protein_name": "AB hydrolase superfamily protein C4A8.06c", "length": 578, "firstPublicDate": "2009-02-10", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the AB hydrolase superfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLKKEQLTVESINDGISKTFSQAFRFLAHHELRKNRTFMLDLGVSILKKFLIDSRDYKVEVVQDFCSRSLTDEFKFKFTSQPIDSKSESDSASYIRNYLGPEGIKQFGGSNWWLYRKSPLKSWWIERRHHIRHNLKCDKVIFYVHGGAHYLSTVRTNAYHIQRHTAALGARTFAPDLRLAPQFPFPCSLHDVLSSYLYLLKSTKPENIIFMGDSSGAGLIVASLVLIRDSKLPLPAGVVYDSPWVDLTHSLPSVVADDAADYIPSEGFHHRASRYWPITNLDSFSTISEKELLNYSKKQELTNFIENSIRKKIQTIKNLIPVLQEMDKEHARIDFDNVDSRLDPNILTTFPFQVQFYTSNANLKHPLISPIFTENLGGLPPSLVLGGSGERLRDEIVYIAHKMNTDVYNGKRTKVRLEMYDDCCHVVTALPFVKEAGIMVRRAANFAYWCLKQHDSSFVSPNKHLDGNPSHANEDMVRLRISRNGEERLMEPKDEIQCLNLPKSALGTIQVKALIRWIDVELILLSKDTKKPARYFAEFKHADLNGYLVKPKEYTMEGENPPLSALVANCKISPEKKQ", "length": 578, "molWeight": 66110, "crc64": "0CAF55554E05A7C0", "md5": "927171F1DF2B44ED79AE0208B73D7E43"}}
{"primaryAccession": "O14223", "text": "This is Golgi apparatus membrane protein tvp15 protein, from Fission yeast, contains 132 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14223", "organism_name": "Fission yeast", "protein_name": "Golgi apparatus membrane protein tvp15", "length": 132, "firstPublicDate": "2008-06-10", "FUNCTION": "Golgi membrane protein involved in vesicular trafficking", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the TVP15 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDKTKMFSAINLGVGGIFVLSGFIKLFSFSFVNALLALFIIVFGLGTIGLEKEIPPIAIKYGSFMFSFLGRGFFYAFMGTLLFSYSGFTSFLGFLVLLAGIAYCGANYVAGLQDYAPRSMRDNDWDDNVDEV", "length": 132, "molWeight": 14518, "crc64": "E58A461BA9F3A0B0", "md5": "A97E9C0D70883716D2D24C91D28C654D"}}
{"primaryAccession": "O14267", "text": "This is Uncharacterized protein C7D4.12c protein, from Fission yeast, contains 759 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14267", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C7D4.12c", "length": 759, "firstPublicDate": "2009-05-05", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the ThrE exporter (TC 2,A,79) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDGNRRVRFNTDRRPYLSPLQTSFPSSTSFQTPTFLIEEDDEDTEDDDGPQVLPVHRAPSPAAFRKRGSITSMDQYLVNMPAVPSPTASKVGLLDARNTDVESYAASYKTQSSSNSVNSLPMRRPTLDRSYSAPMIAAKNLQSDPEKMSNVESTNELPSTTTEAYKLVAAHTAARLEHMRLNALKAANDEGEDVKDNEQDDNIDESDPFANPKASYRGGVLSNLLKLYTNSNTVTSSRISLKHTDPTKWQKHAKRTASSNSLTDLLHASNQTFMAPASGLQSTEEIPQFSKTGHSRGRKFNFHHHSRKNSGLNEEYKITIHLADILQRQKYILKLCRALMVYGAPSHRLEEHMASAAKVLEIEGQFLYIPGCMIVSFGDVNTHTSDMHIVRVNQTIDLGRLKLVHDIYKAVLHDRMGVEEAIRGLDEIFKSPPYFRTWILVVFYGFASATILPMSFQGGWIDLPIAFILGCLVGILQHYIAPRSTMYNSLFEVTGSIITSFLSRAFGSIRYSGGRRFCFSALAEGAIVLILPGYIVLCGSLELQSKNIVAGGVRMFYAIIYSLFLSFGISIGAALYGWMDHNATDSTSCPVSTQMDDKWKILFVPLFTLCLLIVNQARPSQWPVSIFISCAGYVVNYFTAKHFGSNPIANAIGSFAIGCLGNIYSRLGRGVAFAAVLPAIFVQVPSGLAAQGGISSGIEVATSLTNNTYNTSSSSTLDVNSLKFGLVMVQIAIGISVGLFASALVVYPFGKRRSGLFSF", "length": 759, "molWeight": 83359, "crc64": "68D8EA7B5D96924D", "md5": "9328D067EA895E4AA5BCE40DA5D21F79"}}
{"primaryAccession": "O14341", "text": "This is Large ribosomal subunit protein mL38 protein, from Fission yeast, contains 308 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14341", "organism_name": "Fission yeast", "protein_name": "Large ribosomal subunit protein mL38", "length": 308, "firstPublicDate": "2008-02-05", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the phosphatidylethanolamine-binding protein family, Mitochondrion-specific ribosomal protein mL38 subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKRVWPRIPTISNVCRARSIYSAAQENAYRSSVKLIQEYSEKVHKKLQAKLLENPSETSPEIERLQVLSQINLPEVRSKFHKKEIDYTNPVFLYMLKQQWEDYQKLLLLQRLEQMKVIKDSGIGSFSPSVDVQLGFNPENNDSITPGTILPSTVTVKTPWLSVLPFNCKKNHYSVITLDLDVPNYETNRFETHCNWLLTNIPIEASKRVPIDTSKAFFQYRPPIVHRGEDKHRILTLVLRQKSSSISIPSNALVRERFDLSEFCSIYDLEPVGAHLWRSGWDSDAVALLSKHPSVHEYRDIRVERIPA", "length": 308, "molWeight": 35642, "crc64": "EC8EA2766B63850A", "md5": "328C9DD2D6518475278646CFF6E00A0C"}}
{"primaryAccession": "O42637", "text": "This is Complex I intermediate-associated protein 84, mitochondrial protein, from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), contains 797 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42637", "organism_name": "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "protein_name": "Complex I intermediate-associated protein 84, mitochondrial", "length": 797, "firstPublicDate": "2003-05-09", "FUNCTION": "Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I)", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRSHLARNATTTTPNVYRRLHAAVGHHHGLLRPCSATALSARRCLFDCQHDVAHIPRDVALCTRTSKRTFISLFTPKPERFVKLPHFDPGYNVLLQYRKSEVEQERPPPRDQLVTAFKKLTKFKADTNRPLNPNQAFLLRTVLHYLLVTKPEADAPVDLKMSDLENAMDAALLPPKGSPEFHLALARLLHEEIMRRRLILLNPEERKVHLTKDDFARYIKALTQYGGSLEAAGRVKEFWQQLKDERSAVYFRGSGRIWIMVLEGLANEGREEELLQFWEEAQETGGIKYIPGVHQIFVTYYARQDKIEETKQWYSKPIHSGFSPTGETLLELVRSSRRSSQKWNEWLLPVFEQVVQDKFAKKGSLDAFLQWSVLALDKGPDGIKTYLQTMASGDFYQSHEVKVDATTINRLMQAAQEKGNPYMAERFWQLAQDFNIKANVHTYLNQMSYRLDANDIEGAHQIFSKLASGAVEVEFDEDLPVMNKYLRVLCAQQEPNIQHILTITSALEQRHAVLEPETIVALCLVFLNHDKKFDVIDTLSLHSVSISHIERQQIYKAFVDYICSPQTTTDRAWDAYSLLRQYFPETSVDDRVRLMESFFERKKPDMACLVFGHMRAHDDDNMHPTADIYVRCLEGLGRCPIPEQRPSDPASSLKMVHNMLKMDTRVEMNTRLYNALMLAYAAGGDPFTALDFWEEHITRSAEGPSYNSLAIVFWCCELIPLGDRYARPVWQKMLRMDLEVPQLGLTYNALPDPVSKDEFAAWAKEEYPEEWARLESKGQKETEFQGPVFNITRLFEA", "length": 797, "molWeight": 91821, "crc64": "409C8DF345810EDB", "md5": "3B11B3D859D3ED69204F8EF25522C8D4"}}
{"primaryAccession": "O42657", "text": "This is GRIP and coiled-coil domain-containing protein C27D7.02c protein, from Fission yeast, contains 750 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42657", "organism_name": "Fission yeast", "protein_name": "GRIP and coiled-coil domain-containing protein C27D7.02c", "length": 750, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLGRLKDQLNMTLAQGQEEAKNRRRQFQEEDQLRRNNKSSNKLSQNEEDAKNMDSVVQKLNELQNNVVAFQKLLQEKTPLSSIQDLEGFREFMENLEHRYEMTVSEVRRLSHEVNDLQTDRENLKHQFEDQIEKLNSEISNQNSLILQKKDELEKSIQRCSELEEKINSLESAQSIEQEVISSLKDDKTVETKNDVPEVSRPSTDTIGVSSALSKKKKKRNRKNQKKKSTKQNIEATTENDALSESISTPDIQKVAQSEDVDAEQDTVADSKEEERRDIANDDLIVNANAKEPMHHFSFTDLDTLLNWPKYVFHHHKIHLADTIPLVFLDLKPKEYTVDLETPKLVEELTKQLHVAESTLKENSEKFKQNSESLKSRVDNLNDYITKLQNEIDECRRNLLWAESSCETIREENQKNIKKLNDAESLKSRLLQSRTQMQTELDSYITSNSQLKDEITSLKQTVSESEAERKRLFSSAQEKQLQMKETVNKLTSLQEQNNEFDRQLKEQEEDLQNKEEELTELRKLLREQTQDSQKLRLLVEQLELERQDLKQAGENHYSNLSSDYETQIKSLESSLTNSQAECVSFQEKINELNSQIDELKLKLNEANKKYQELAISFENSNVKTQSVEPDNGLSLEALKNENQTLLKNLEDSTARYEHLQKSFKNVFNQLRKQQPSNHGRNSSVSRSSSSVEVNSKHPGSDDMLIDKEYTRNILFQFLEQRDRRPEIVNLLSILLDLSEEQKQKLLSVKY", "length": 750, "molWeight": 87265, "crc64": "A469AD95C5787042", "md5": "3301FEBE18FE9D809ABD4CC28D50613F"}}
{"primaryAccession": "O42927", "text": "This is Uncharacterized protein C16C6.03c protein, from Fission yeast, contains 207 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42927", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C16C6.03c", "length": 207, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNPTSFIYDKPPPPPIINKPFEQTNSSASLTQKNSSSETENVGRHGKRRMDQDLSFKPTKRGSGRGRGRSFRGGSHAGNTRGACAVDGIEYLKRRNISINTPEEIEAWIQERKKNWPTESNIRSKQEKEKVMENLGAADTSQSIDAQPTPSQHPLAHHEPHEKRGPPKKKSLYTKLLNTQLEQENIFFLQFMKLYLKKMGMVVKPVS", "length": 207, "molWeight": 23469, "crc64": "6E7A0F1009E68A43", "md5": "E78315DD10F53399ABB9875B7348D4B0"}}
{"primaryAccession": "O42928", "text": "This is Uncharacterized protein C16C6.04 protein, from Fission yeast, contains 350 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42928", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C16C6.04", "length": 350, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MDSFHPTPGKPTTATSNSSLNFFVRNREKSIRCSSLHQTFTAPSPEASPSIGLRYVNYSMSDETDESMFPLDSELTDMEDDDTEYISDSTTDLPSAAMARGTRQLSYNENLDQRSFSKTPNKHIEVKNLKDLCSPSHSGRISKSLCPVLRRKSLLPKPKMFQRVASALYEESSPLELEIRSESEFSKMFFEPKKSSSFVSRAASPAMVGPGVPFYSSITGANGNVLAPSGSLKAVENSDVIESSAEDSSNTDNPSTKPSNEMPISPLLSSSVFFKDTEMSTPNSNHSRSRTPSSKKRTRWGEEIIDLSKRRAVSPSIYYDLDKKCSPIHSVMVSPLKIKDTHEVLMNLKL", "length": 350, "molWeight": 38762, "crc64": "C0D15A7F13C6AD89", "md5": "E90B9B0FEFF27FDFDF006732EAE513AA"}}
{"primaryAccession": "O42973", "text": "This is Uncharacterized protein C20F10.03 protein, from Fission yeast, contains 446 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O42973", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C20F10.03", "length": 446, "firstPublicDate": "2008-06-10", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the IFRD family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGKKDGKRQLMSDDDSFDTISILSGSMDQLSVGSMEDSGILKGSKTWLEELESTIDDLIEVKKIGAKEREEHLEKIYVICTRHYAKRISENVASLEELLLKIFNGPRSDKELILTIRIMCTFCLASVFQVEELWTKTEGRFNALANDAESSGIKCESILCFSLLTALLDSEADVIEFGDFLISILESDGAVVNSEDDEGVVGCACQALGLLLTCVTTESEFLASAAEALSEQLDAASIDVQLAAGQALAALFERVNEIRPDKDEENDESDVSQTSKFDDIIPDRNQLLITLRDLASESSKSIGKKQRKVLHQVFRNVLQTIEEPNARNILRNSVRIGQSTVQLDSWKKILRAQMLRYVLGSSFSEYFAKSTFIRYFLGYSGYVAGLSSRDPDSDFDSDNVDEYIDDHKRGLSSTERRDLDRVRDKQKKQDQRVRADYINSVYFSQN", "length": 446, "molWeight": 50043, "crc64": "4D756D3D4C7C7379", "md5": "EB6D7C413CECBB9F8F11AB74B8B3B3CF"}}
{"primaryAccession": "O59714", "text": "This is Uncharacterized membrane protein C3B8.06 protein, from Fission yeast, contains 511 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59714", "organism_name": "Fission yeast", "protein_name": "Uncharacterized membrane protein C3B8.06", "length": 511, "firstPublicDate": "2009-05-05", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "To yeast YCR061W", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDGMHMNSTGDNPIEIDFENYANHMNKFLMAHIICMIIAYVFILPAGIVLAMAKSKAHIPVQIVYVILTLIGYIFAHISHHKASPENYYKGNIHRPVGRFFMWITFLIAIVGITTSILKKRMLKEYQPAAEAPGAMEDPEQALQRNSLDDGAPLLPREGNSSDEYLPPQSSRRDVSSEKPSIPSISFINIRSWRTIPKKWCVLQVLRYFHRILGHLWLYVGFFESCTGIVLLAGIFKGQHIFNGLAHWIKGAIFLWYGILSFGEYLGAFSEYGWAWNVVPKQLSEKRFAKYVPTKEMVESFLLFAYGVSNVWLEHLGNTDGKWNHHDLQHASLAFMLWWAGLCGILVESKVVHRLLNATLSATLGQRRSEDSEHSENGLPSYNVFPALTVFFTGIMMSAHDQTNHVSTVIHVLWGRLLAAAAIARICTYIMLYLKPPSSPWPTRPPTEIITSFCLICGGAMFMASSYDVVNKIRLNEMSPMLIMNISVAFTCIVMGLEVMFLILKGYASSR", "length": 511, "molWeight": 57703, "crc64": "BDDDDE7650B2225E", "md5": "B29224A026AA02BFBD24584F8EEC05B8"}}
{"primaryAccession": "O59746", "text": "This is Uncharacterized transcriptional regulatory protein C530.11c protein, from Fission yeast, contains 819 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59746", "organism_name": "Fission yeast", "protein_name": "Uncharacterized transcriptional regulatory protein C530.11c", "length": 819, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLENSTAVHGVRLSDSPEDPFLRKRLASNTQLNQKKIRFTENENDLSPERAQKEPVSIPHGRYTWSTSPDTDSSHLPSTPPTVDIPFHHPHTIHSPTFTLSVSPDSQSSSATHQNDYISSPHADFSFSPPASKIQSHEPLNDMAAVHPLRPSHVSGPLSPPEPKAASVDHSINPAYNASFRLPDGPLWTEGSENLPSLDIQLQLAHIYFIYAHGQPYVLFHRDSFMEALKSQRLPPVLVLAMCAVAIRFWQTDKYDKNELFEQWFNRASAIAMANFDKLDLVYVASFVMLSYVCAATSKYWMFAGMAIRMVVALHPNKTPNLPYYDRPDSPLPFEIRVQLTRRLFWDCFMLDRLNSLYCNTQFLNLEDIHVPLPMRETLFMYKAHAVTETLTGKPSSPDSFTNANPTTAPIVSRNAQDNMGMLAYMIRMVSIWGRVVRCLKSYSQKQSNPYPFWHAKSTFKQLDQELYEWEKNLPNRLRYSRQTLLSYHMMGQGGQFACLHLIFLQIHLYVHRYAASISSVPFSHVKSPPTVFENQSAVLASQCANAICRIIQDCTELSISLAAPFTASSAYLAGTVLLYHYITRGSEVQASKAAVHLPIAKRHLAQLSVYWPALGMYAKALDAIAFHQGALVTPSVPPVIATVSKTNTTNTGVQQRGNVGVTTTGSILTQSSPALPVQPVPLAYSKPAPTTKSSLTELAYNTNVSLPPRSPGTGSLAAGNLPNEKAPSLMTMVNGGPVPGDIGEASIPVVQNLQPSTAHVDPESDLGRVIKICDWYQSPSSDVLLSKPLQLNSSEEMEQQCIDLSRHNTLLNLSSYGI", "length": 819, "molWeight": 90824, "crc64": "09FD2882A806C40F", "md5": "BAAD943FDADB517D697D8C50A15C847F"}}
{"primaryAccession": "O59792", "text": "This is Calnexin-independence factor 1 protein, from Fission yeast, contains 320 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59792", "organism_name": "Fission yeast", "protein_name": "Calnexin-independence factor 1", "length": 320, "firstPublicDate": "2007-09-11", "FUNCTION": "Induces a stably inheritable state of calnexin independence called the Cin state when overexpressed", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSEEIITESIVKNFGSAETSVGEKQPKRKRSEVRAEKLKARKLQKAAEIVQKQKENRKILKDVSLKRLSKSLDRSLPSENTIDQISFNHAMSEEDASGYQIGDKHKNLLLYKLSSSSGSVFTENLYSTIQEFLSAQKVDIADSKNTYVFGSTFDKKSHALVKTSDSVRSLKYGSFVKACAPLFRFASGIIKAHAPHFHQALLKLELAPSALRFGVFPNFSLQSVSNGYMSMESNFSSIKYGFVVIIIVGELNDVELKIPAISHSLKLKDGSILVLRSSLLHQWYSLPKQSILYEIRLFAMSSLWHYEKNKSIKIAKKDDI", "length": 320, "molWeight": 36018, "crc64": "99C1C33677D0AD86", "md5": "CFDEFDE2756E7954ACCD7EAAB3408ED8"}}
{"primaryAccession": "O60053", "text": "This is F-box protein pof12 protein, from Fission yeast, contains 440 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60053", "organism_name": "Fission yeast", "protein_name": "F-box protein pof12", "length": 440, "firstPublicDate": "2002-03-27", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTTDVKAKNPASIFSHETLLHVLNDLSAHDLAALERVSRSWNSIVRRSSVWHNLYLSEFGTKHLRRHGRIEKKRRNWKGLFRRQSNWKDGRCKKVESMLPQLLNSEKSVGEDRLGLTLTHQNNIYFCNDVQISKWSSVGNSLKCQAISSFRDETVKSGPAVMCLDNASLYIGLKDGNLLHVTVHETGFGNIENLATFSTKFVALSSHKNYICGLTNDNNLYILQHSHQAGTKLKVLGKYHVSSIEKQVAIHFQQSKEGYEVVHVVFNDYVLSGGWTVSLQEFVFNEYCVKSSRLALHDNKDIEYSQQPASAIFMYGSYILTSHPDNSLILQRLYSTNNELRIKFLGRLLGHVCGVQISKLFSCGRIVSVSKNCADICVWDLHDTNYQSIVSPLMLTCTNIHNKPVSDYEKECKVQDIGLYEDTILITLSDGRILKFLFNI", "length": 440, "molWeight": 49997, "crc64": "471FBAC7F3921E81", "md5": "366A422A63158A84F15CDAAD95A7D259"}}
{"primaryAccession": "O60113", "text": "This is Uncharacterized amino-acid permease C15C4.04c protein, from Fission yeast, contains 542 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O60113", "organism_name": "Fission yeast", "protein_name": "Uncharacterized amino-acid permease C15C4.04c", "length": 542, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the amino acid-polyamine-organocation (APC) superfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDSVSNVSVNEQGKFNDKEEGFSNLKSLKHVSHSETDFEVSNDEDNQLLELGYKPVFKREFSTWATFSFAFSISGLFATVVTTYSYPLISGGAPSAVWCWLIAGAGCMCIALSVAELVSAYPTSGGLYFTCKDLVPARSMPVVAWVVGWLNLLGQAAGVSSTDWSCAQLLLAAVSISTDLKYIPTNQHIVGVMAAVIVFHGLVNSLSTRWLDRITRFYATFHLIVLVVCMICLLAKCPKFNTGKYVFTDVQASSGWHPIGFSFLFGFLSVAWCMTDYDATAHIAEEIENAAVRAPNAIALALSITYVLGWVFNIVLAFTMGTDLDSLINSELGQPVAQIFYNVLGKKGSMAFTILSFIIINFTGITAMQANARTIWAFSRDQALPFSRYWYKINKTTTTPVIAVWLNVVFCIALNLIGLGSIEAIEAIFSVCAIALDWSYVIPIACKLIFGKRLNYKPGPWNLGWASHFVNAYAVCWTAFVSVIFLMPTVRPVTPQNMNYAVVVLAGVLLFSLVYWWSGARKSYIGPRINVDMESEDPFKTE", "length": 542, "molWeight": 59726, "crc64": "17D9B15C04299468", "md5": "65E7E6D026880D66B88429749F86877D"}}
{"primaryAccession": "O65009", "text": "This is BURP domain-containing protein BNM2A protein, from Rape, contains 282 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O65009", "organism_name": "Rape", "protein_name": "BURP domain-containing protein BNM2A", "length": 282, "firstPublicDate": "2016-02-17", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MASLRFSVTFPALLSLLLLSLWVVEAYTSRKLISNNEQEGQNISHLFKDGEFEDPTMYMFFKISDLKLGTKLPIYFNKNDLRKVPPLLTRQEADLIPFSESNLDFLLNHFSISKDSPQGKAMKETLKRCDFKAIEGEYKFCGTSLESMLDLAKKTIASNADLKVMTTKVMVPDQNRISYALHNYTFAEVPKELDGIKVLGCHRMPYPYVVYYCHGHKSGTKVFEVNLMSDDGIQLVVGPAVCHMDTSMWNADHVAFKVLKIEPRSAPVCHFFPLDNIVWVSK", "length": 282, "molWeight": 32089, "crc64": "375CEE9717C089FE", "md5": "C6B8626D167B450BA828A62738AE210F"}}
{"primaryAccession": "O74317", "text": "This is Meiotically up-regulated gene 98 protein, mitochondrial protein, from Fission yeast, contains 113 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74317", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 98 protein, mitochondrial", "length": 113, "firstPublicDate": "2004-07-19", "FUNCTION": "Has a role in meiosis", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSIPVMQLKHELALKAREEYLRKELPLKVRANTSRMNPGAKTWIPQINHRKSRNHYNRKETCQFPPLYNVEAKINHSYSAFYRPFTKRENGLWYANPYYMQHGPNGNYHHVYY", "length": 113, "molWeight": 13640, "crc64": "C004E14B6894908A", "md5": "F332CDFB08A52E4D060A49B3A0748A4B"}}
{"primaryAccession": "O74551", "text": "This is Uncharacterized protein C777.12c protein, from Fission yeast, contains 238 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74551", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C777.12c", "length": 238, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MKINLFFVFLFELLHFVAAYSCEGDESAAIEAMNVLQVPYEKYNTDPVCAFDNSTVVELSDKTWDHVIESGKWFVQLTAEGCANCTLGELLFNDLSHAFHEKYPDVHFARVYLSSSLELSVRLLISRIPSYYFIDNQNFYRVSPQVLPKNKAIALYEKDGFKSMKKEQGFFSVNGPLKSFYWVFGKALALYGHLSQKYTPLGMNVAIFGISAYIMYRSSKKAKQKQAAAAAAAAAKKK", "length": 238, "molWeight": 26889, "crc64": "A6C572B91512F92A", "md5": "86704846CA0BE05E18E9399DFD2EAEE7"}}
{"primaryAccession": "O74628", "text": "This is Uncharacterized oxidoreductase C162.03 protein, from Fission yeast, contains 292 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74628", "organism_name": "Fission yeast", "protein_name": "Uncharacterized oxidoreductase C162.03", "length": 292, "firstPublicDate": "2009-05-05", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the short-chain dehydrogenases/reductases (SDR) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKSTFSTVLITGSSKGLGYALVKVGLAQGYNVIACSRAPDTITIEHSKLLKLKLDVTDVKSVETAFKDAKRRFGNVDIVINNAGYGLVGEFESYNIEEMHRQMNVNFWGVAYITKEALNLMRESGKGGRILQISSVAGYYPSPCLSMYNASKFAVEGLSQTIMRELDPNWNIAITIVQPGGMQTEWASSNMQWAKPHPAYENDRSWRPFWENYHGCEETDPNKAAELLYSIAKLDRPPQKLVLGHDSLELIRKQHQDIGEELESNVALSTSVAKDDFDPASVETLRQNLQSM", "length": 292, "molWeight": 32614, "crc64": "BD6B1F3E7F976DC1", "md5": "78C367E838759BCA88D6F3136D70BF62"}}
{"primaryAccession": "O74648", "text": "This is Isoamyl acetate-hydrolyzing esterase protein, from Fission yeast, contains 246 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74648", "organism_name": "Fission yeast", "protein_name": "Isoamyl acetate-hydrolyzing esterase", "length": 246, "firstPublicDate": "2008-01-15", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the 'GDSL' lipolytic enzyme family, IAH1 subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSDSQDKNYISFEKTEIGQIVSEAPAEKYVSFQKKYFNRLTIIGDSITQKGFTPGGYCAELMNFYQRRLRVDVWGFSGYTSRHVLRYLPEIPLEIDSTKLLIVFLGTNDCQLTETGYMCPVDEFKNNLLALTRPFPHSKIIIVSPGICTKDICFKREQEPYVIAASETVNTLNKSKANSAGLINLYEITKSYPTPELLFTDGLHFSSLGYSLLFNEIVATISKAWPELLPNNLPLQFPHWSEILFT", "length": 246, "molWeight": 27991, "crc64": "DBE6BFCD6359E78B", "md5": "F198A29B2C5A64A4BB41CAF4E00D3A79"}}
{"primaryAccession": "O74830", "text": "This is Putative glutathione S-transferase C1183.02 protein, from Fission yeast, contains 220 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74830", "organism_name": "Fission yeast", "protein_name": "Putative glutathione S-transferase C1183.02", "length": 220, "firstPublicDate": "2008-01-15", "FUNCTION": "Involved in the oxidative stress response and detoxification", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the GST superfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFLGTLYSFKTNTRTVCLLELAKLLDLQVDLVETYPHKFSADLAAKFPLQKLPVFIGADGFELSEVIAIVKYFYEKGKHNDKEGLGPVNEVEEAEMLKWMCFINFDIVTPQNVRPWVGMFRGNIPYEEKPFKESATRAIDSLKIPNELVKDRTYLVGDRFTLADLFFGSLLRIFFNSIIDEKTRKELPHLTRYYITMFHQAKLETYFPLELPLTVTVAKK", "length": 220, "molWeight": 25504, "crc64": "4BB915229C886213", "md5": "C183A66BFA7F0681D3282E65D29412BA"}}
{"primaryAccession": "O74886", "text": "This is Uncharacterized protein C576.02 protein, from Fission yeast, contains 236 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O74886", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C576.02", "length": 236, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the HyuE racemase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPTILVINPNSSTFITTSMEEKLVPLVPSDVKLRFLTCPQPGAAVIDSITEATLTAALVFQALTPSVLDGVDAIAVACYSPTPLVDMIRESFALPCMGIVQASVLSALSVGQRIGILTSTYRSECLLYELLDSFGVSRTRVAAIASTGRTVLQLSQMPSQERETLLVQKAQELANTKGADVICLGGAALAAIRDQIQVAVGPNIPIIDGVHAAVELLAGLARQNLHTSKFGIYTYP", "length": 236, "molWeight": 24953, "crc64": "0EA5D8597760A41A", "md5": "8007ADCF23BA12ABF1BDFE4B1EE0D4EB"}}
{"primaryAccession": "O94358", "text": "This is Uncharacterized protein C428.10 protein, from Fission yeast, contains 845 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94358", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C428.10", "length": 845, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKRKSSHYNDAHASHINEDIEESYKDLYNNLSPSSTILLLLYARWFPATLIHFLDKYYTSTPILIDMIHKQCIYNPPKGSLHVQLEYYLAFLNRMALIFDRFPDLFPTEISKVKFFTKDFSKKDKLTALDTYRSFPGSTWKTIVTFATQEVFYLPEGLEPLKRDFSSMDKLKLIGKITYKLRLKGDTALKFAYLHAPSDVRDKVFDDAFWQEIITPKASLEQQSNNIPTGIQDSSKYTVNGPTERDNKSMKSFVRSFFTSTDSSVADTTIIPSMTQQFDKDPSTLVQSSIDKEIQVKEDGTTSSVAVNAETAVQNVNGTIKESQGTESISFASKNNSAPSADANNGNMTKLVSKEKAFLNTVTTPNADLIISEEDELTEMTLRTANGSEPTKKSNRSEQSKTVANTNVGSKNGTTPRSFAQKSSKRIKPTEGSANLNTVTELTGIGSRIAMNGSSVKASNISTEKSKTIAKPKPAKELSPQATLNSPIQSAEAGNVELKLHPQTPDRIVKVERKVHSLNMTLRSPKAGSAGKENSWRSKYLSEGKNSKAKYTAKQPSYDRAGSSLASPTKSSASPLVKAPKETPERLCTENQSTENEDQANLKESELPKEKSDIQPKNSRSTIEYIETSTRVYEMPKDTIPSRFKTSISTEVHDGRLKKYPYYHVKTPEKGTTVVSRTVTSPKSGAYASPSKASYNQDSSPNASLEQCFVQRSPSKMLTTLRNNSSTFPSLRKNAMIARKSTADSLSSPKRQSVPSTPKASLSPRVHKSMTYSPSEASPLYANKSPKSSTMVPLMKYKSGLNEGMRTSSIYSSTSSPYIRDQYFLNRMLTNGSHNGSPSWRDGLL", "length": 845, "molWeight": 93695, "crc64": "03ED552BA1455F26", "md5": "84B6F735CC63840A43E45C15D5D27101"}}
{"primaryAccession": "O94378", "text": "This is Uncharacterized protein C1604.12 protein, from Fission yeast, contains 860 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94378", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C1604.12", "length": 860, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MERIQENDPIIKSADESKESPAETLSSIFKRPKIKSSSLNKAYLGKAGSVNGASNTSTNQISSLKVDVSSPPSTAPGSAGSTPKTTPVSLNAGVPPSNTGANITTNSNNNAQTISSSSQSVGHIDNPSGLGTHGKVRLSIKLSTGGSGGSSVTGKRTAPGNPWAIRSAERLASNPTSIGTSSPESIDNNSNNKKSAPSLYAAAAASAARHSMSAAYASFTGTVYDSNGNVIKGLDTSSSLSSSSHPSHEALSTIDTKNLQALAASAAPSSCRQQPVDEERQDRVSKISKHFQDSGTPVSEEVSPTRLPSPTSARRASHLSEGKWDEIDDEDDDDWGSTIEFEDGTTVVIDAKTRRYEPVKRQDTLASNHVPSAPSNESVSSAAPSKIPVPEEASINEHSNITDEAVSLPEPVYPNAPTSAVSVHNPTISDEAEPTERAFLKKEKPQISKEKKNPNVTHEEFVEKSTALPRHINKVEIVSDSSESFAHKNNEKRFDKEASGRINDLRAEQQQIMLEARQKAIERRRNEEEELARSRERARKKAEEIKISSSKMNSSPTITNERSSNVESSKKVEAIYTKEPQSITNSPEGLHSNQETTEIDPSSPRDDSTPLSWRSHSHPIPPVQVSPLFTSDKNDPLQLNPQSDDSTSSPKHGKSRSIDEVILSIKDVIFDNNLYKQRSYQSGVAANAHLPHRVPNEHGGVSRIGNSNALGQPVSSSSSYSHSKGRDTRSSSYVVSSETSSLKSSRLILSHANSVRIQRSKGDVILNLHLPKVNPERFLPTKSLKLEEMKPLEEKVPIYRSSSKQPLRIHPTHPLRVTVCLPGSKTIQVARRSFRNSMNANRYDPQRRERIDSGLWRAKN", "length": 860, "molWeight": 93286, "crc64": "BA44A7BC4C565C63", "md5": "B95107CFAB20C9A8BCCC3C156779C684"}}
{"primaryAccession": "O94432", "text": "This is Uncharacterized RNA-binding protein C660.15 protein, from Fission yeast, contains 474 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94432", "organism_name": "Fission yeast", "protein_name": "Uncharacterized RNA-binding protein C660.15", "length": 474, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MGGSDFEDDELFKDLYGEENEKKVESASGNQETSNVTPTKENEGYEELEKSGEAGAERTKENPFREEPGADFDRSGSDQQYSAEAEANQEDDLNETSQQAPDPSSYDIRGQALSSATWDNAEDGENSKNDNYNENQSALTGSGAMESNEDNAEETSPFNREDGKMFIGGLNWETTDDSLRDYFEQFGEVLDCTVMRDSTTGRSRGFGFLTFKNPKCVNEVMSKEHHLDGKIIDPKRAIPREEQEKTAKMFVGGVPGDCTEEEFRNFFNQFGRVLDATLMMDKDTGRPRGFGFVTYENESAVEATMSQPYITIHGKPVEVKRATPKASLRDSHDRHQHGYHGNANPYYAQNMNMYGGMTPAMMAQYYRQMQQYMEAMRNMPAAAGAVPYPQPVMPAGMADWQQQQQQGAAYFDPSKMNQGTGDGVPFSPSMPSGSSRGGYHGRNPGGPNRQRYRGRRDGRGGNTGGGHSFHPYRR", "length": 474, "molWeight": 52818, "crc64": "AB7C735FAACEEF51", "md5": "409F14724EBBAF711E6E4D9F401B735C"}}
{"primaryAccession": "O94500", "text": "This is NADH-ubiquinone oxidoreductase 51 kDa subunit homolog SPBC18E5.10, mitochondrial protein, from Fission yeast, contains 452 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94500", "organism_name": "Fission yeast", "protein_name": "NADH-ubiquinone oxidoreductase 51 kDa subunit homolog SPBC18E5.10, mitochondrial", "length": 452, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the complex I 51 kDa subunit family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLSRGHCCKLKHSFNGLRNVALKRLVGSKAGYRMFPNLIEKRIRRIDDALADGEYENLSEILKYDPLNIIELVQESELRGRGRYGFPTGEKMLSLYKATSSERGRKEKPVVIVNAAENDIGSFKDRLLLRHEPHKIIEGAIIAARAVEASACYLFIRKDYYEETVMMQKCIIQAYAKKLLGKNLLGTSIGLELLIHPGAGSYITGEESALIQSLQGEFPVPDIPINNTITSGLFGLPTLVLNVETVSNLPAIIKKGPKFFISMGRPNNRGTKLFSISGEVNEPNVIEACMSIPLKDLIENYAGGVRGGWNKLVGIFPGGPCSGILNKNQCEQVTMDFDSLKALDSSLGTGSVIVLNDHDQIFESLLNFAKFYSTNTCHTCPVCRDGVEDVIETLKGLKDGHAHLSQLKDMFSKFNMPSSSKVFCGFGDSMRHQIHSIQRNFPDQITFRTKVT", "length": 452, "molWeight": 50095, "crc64": "6C199251A7598374", "md5": "C5E3F50FD48E3FC9F89830E6C2FED2B8"}}
{"primaryAccession": "O94521", "text": "This is Probable pyridoxal reductase 2 protein, from Fission yeast, contains 333 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94521", "organism_name": "Fission yeast", "protein_name": "Probable pyridoxal reductase 2", "length": 333, "firstPublicDate": "2007-11-13", "FUNCTION": "Catalyzes the reduction of pyridoxal (PL) with NADPH and oxidation of pyridoxine (PN) with NADP(+)", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the aldo/keto reductase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPIVNGFKVGPIGLGLMGLTWRPKQTPIKQAFELMNYALSQGSNYWNAGEFYGINPPTANLDLLADYFEKYPKNADKVFLSVKGGTDFKTLAPHGDPESVTKSVKNALTRLRGKKKLDLFQCARVDHKVPIETTMKALKAFVDSGEISCVGLSEASAESIKRALAIVPIAAVETEYSLFSRDIEKNGILDTCTQLSIPIIAYAPFCHGLLTGRVKTAEDLKDFIKAFPFLRNMDKFNPKVFEKNIPFLKAVEQLAQKFGMSMPEFALNFIIANGKGMIIPIPGSTTVQRAESNLSALKKSLSSEQLEEAKKVLDKHQIFGLRYNKQLESTLSI", "length": 333, "molWeight": 36844, "crc64": "D69C0BEE8735E0F2", "md5": "21F6007E4BACF4A8ECDAEA3BCBA01507"}}
{"primaryAccession": "O94601", "text": "This is Uncharacterized protein C622.14 protein, from Fission yeast, contains 321 amino acids, has 1 C4-type Zinc finger, is soluble, locates in Cytoplasm.", "functionDomainRange": [{"location": [17, 40], "description": "C4-type", "keyword_description": "Zinc finger", "textural_description": "C4-type Zinc finger"}], "meta_data": {"primaryAccession": "O94601", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C622.14", "length": 321, "firstPublicDate": "2008-02-05", "FUNCTION": "GTPase-activating protein for the ADP ribosylation factor family", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {"C4-type Zinc finger": 1}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSYKLDQLTRLPENKKCFDCDAPNPQWASCNLGIFICLDCSGQHRGLGVEKSFVRSITMDNWSERQVKMMEVGGNSNAKTFLSTDPMFSAAGSIREKYNTDIAEDLRQKIRAEVDGVEWVKVDRPKSVSSHASVTSSSTVPTIPSVSKEANDKYFAKLGSINSQRPDDLPPSQGGRYQGFGSSNSVNPNSSARNNGGSFLDQLSSNPVSALSHGWNMFSRSVSQQIQDVNKSYIQPGITKVQDPETRKDYMNAINNFSSNVQEGAKQSFTQLKSFLDENVYSENPQNTRGTYDAEIDSPYSALAASPPPEDYSKKNFDKHD", "length": 321, "molWeight": 35518, "crc64": "B0E79DB6A2AA180D", "md5": "11D2668046B2B25D9452FAD0B25F31F2"}}
{"primaryAccession": "P00288", "text": "This is Plastocyanin protein, from Broad bean, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00288", "organism_name": "Broad bean", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "VEVLLGASDGGLAFVPNSFEVSAGDTIVFKNNAGFPHNVVFDEDEIPSGVDAAKISMPEEDLLNAPGETYSVKLDAKGTYKFYCSPHQGAGMVGQVTVN", "length": 99, "molWeight": 10394, "crc64": "62F74CFB1343A420", "md5": "A4BBFA2BF4B3A5CF6F2D20A0C0C7E030"}}
{"primaryAccession": "P00290", "text": "This is Plastocyanin protein, from Garden lettuce, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00290", "organism_name": "Garden lettuce", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "AEVLLGSSDGGLVFEPSTFSVASGEKIVFKNNAGFPHNVVFDEDEIPAGVDASKISMSEEDLLNAPGETYAVTLTEKGTYSFYCAPHQGAGMVGKVTVN", "length": 99, "molWeight": 10360, "crc64": "202074D378F54984", "md5": "C93FCE8BF257FEEC67C4EEB18B0A17A6"}}
{"primaryAccession": "P00291", "text": "This is Plastocyanin protein, from European elder, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00291", "organism_name": "European elder", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "VEILLGGEDGSLAFIPSNFSVPSGEKITFKNNAGFPHNVVFDEDEVPSGVDSAKISMSEDDLLNAPGETYSVTLTESGTYKFYCSPHQGAGMVGKVTVN", "length": 99, "molWeight": 10461, "crc64": "61BEDBC49D964C26", "md5": "D3FE2A6776382A7D869A50875EADD0BA"}}
{"primaryAccession": "P00292", "text": "This is Plastocyanin protein, from Vegetable marrow, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00292", "organism_name": "Vegetable marrow", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "IEVLLGGDDGSLAFIPNDFSVAAGEKIVFKNNAGFPHNVVFDEDEIPSGVDAGKISMNEEDLLNAPGEVYKVNLTEKGSYSFYCSPHQGAGMVGKVTVN", "length": 99, "molWeight": 10494, "crc64": "9C72D8E9B0A6017E", "md5": "05B7E87A70D34BD29431250EA11A7977"}}
{"primaryAccession": "P00293", "text": "This is Plastocyanin protein, from Cucumber, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00293", "organism_name": "Cucumber", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "IEILLGGDDGSLAFVPNNFTVASGEKITFKNNAGFPHNVVFDEDEIPSGVDSGKISMNEEDLLBAPGZVYZVZLTZKGSYSFYCSPHQGAGMVGKVTVN", "length": 99, "molWeight": 10556, "crc64": "BB25F97B8C0D8044", "md5": "05525FA0CD2C6A45CB00E06E700A3285"}}
{"primaryAccession": "P00294", "text": "This is Plastocyanin protein, from Shepherd's purse, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00294", "organism_name": "Shepherd's purse", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "IEVLLGGGDGSLAFVPNDFSIAKGEKIVFKNNAGFPHNVVFDEDEIPSGVDASKISMDENDLLNAAGETYEVALTEAGTYSFYCAPHQGAGMVGKVTVN", "length": 99, "molWeight": 10384, "crc64": "30BA97B58B9580F1", "md5": "EEEE164F904FEFBB7D288DD92933D1E7"}}
{"primaryAccession": "P00295", "text": "This is Plastocyanin protein, from Dog's mercury, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00295", "organism_name": "Dog's mercury", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "LDVLLGSDDGELAFVPNNFSVPSGEKITFKNNAGFPHNVVFDEDEIPSGVDASKISMDEADLLNAPGETYAVTLTEKGSYSFYCSPHQGAGMVGKVTVN", "length": 99, "molWeight": 10486, "crc64": "009AB50FDA9B7033", "md5": "D45FC0A5D60FED2C76ACFBC5EC66C034"}}
{"primaryAccession": "P00296", "text": "This is Plastocyanin protein, from Potato, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00296", "organism_name": "Potato", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "LDVLLGGDDGSLAFIPGNFSVSAGEKITFKNNAGFPHNVVFDEDEIPAGVDASKISMAEEDLLNAAGETYSVTLSEKGTYTFYCAPHQGAGMVGKVTVN", "length": 99, "molWeight": 10330, "crc64": "EFDB76CE1EB3DDA1", "md5": "BB3AD737FD843C5E5B7466718A6B460A"}}
{"primaryAccession": "P00297", "text": "This is Plastocyanin protein, from Chilean potato-tree, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00297", "organism_name": "Chilean potato-tree", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "IEVLLGSDDGGLAFVPGNFSISAGEKITFKNNAGFPHNVVFDEDEIPAGVDASKISMPEEDLLNAPGETYSVTLSEKGTYSFYCSPHQGAGMVGKVTVN", "length": 99, "molWeight": 10399, "crc64": "DDC400E7E095EF9A", "md5": "E1E8055A8E5AB1E8B387D0FB557F65E1"}}
{"primaryAccession": "P00298", "text": "This is Plastocyanin protein, from Bitter dock, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P00298", "organism_name": "Bitter dock", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "1986-07-21", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "IEIKLGGDDGALAFVPGSFTVAAGEKIVFKNNAGFPHNIVFDEDEVPAGVDASKISMSEEDLLNAPGETYAVTLSEKGTYSFYCSPHQGAGMVGKVTVQ", "length": 99, "molWeight": 10355, "crc64": "1CCB254EA0B1206A", "md5": "80BDF3ED27C399ACC1719EC85DEE20C4"}}
{"primaryAccession": "P01405", "text": "This is Toxin 4.9.6 protein, from Western green mamba, contains 60 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P01405", "organism_name": "Western green mamba", "protein_name": "Toxin 4.9.6", "length": 60, "firstPublicDate": "1986-07-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the snake three-finger toxin family, Short-chain subfamily, Orphan group XI sub-subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MICYSHKTPQNSATITCEEKTCYKFVTKLPGVILARGCGCPKKEIFRKSIHCCRSDKCNE", "length": 60, "molWeight": 6800, "crc64": "291E62A51D3DF72B", "md5": "AF877EF96658FD22ED2347325D8F005D"}}
{"primaryAccession": "P01406", "text": "This is Toxin S5C4 protein, from Eastern Jameson's mamba, contains 60 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P01406", "organism_name": "Eastern Jameson's mamba", "protein_name": "Toxin S5C4", "length": 60, "firstPublicDate": "1986-07-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the snake three-finger toxin family, Short-chain subfamily, Orphan group XI sub-subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MICYSHKTPQNSATITCEEKTCYKKFVTNVPGVILARGCGCPKKEIFRSIHCCRSDKCNE", "length": 60, "molWeight": 6772, "crc64": "D8093236EFA69364", "md5": "F38DA5F42F7AC9F751AC4359260A022B"}}
{"primaryAccession": "P09031", "text": "This is Ice-structuring protein protein, from Yellowtail flounder, contains 97 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P09031", "organism_name": "Yellowtail flounder", "protein_name": "Ice-structuring protein", "length": 97, "firstPublicDate": "1988-11-01", "FUNCTION": "Contributes to protect fish blood from freezing at subzero sea water temperatures, Lowers the blood freezing point, Binds to nascent ice crystals and prevents further growth", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the type-I AFP family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALSLFTVGQLIFLFWTLRITEANPDPAAKAAPAAVADPAAAAAAAVADTASDAAAAAAATAAAAAKAAADTAAAAAKAAADTAAAAAEAAAATARG", "length": 97, "molWeight": 8865, "crc64": "62AD582DF8E459B6", "md5": "8E482501DBF3B9A1457CF018D2DFB105"}}
{"primaryAccession": "P0CI04", "text": "This is Omega-theraphotoxin-Asp3a protein, from American tarantula, contains 42 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P0CI04", "organism_name": "American tarantula", "protein_name": "Omega-theraphotoxin-Asp3a", "length": 42, "firstPublicDate": "2010-11-30", "FUNCTION": "Inhibits voltage-gated calcium channels (Cav) in rat cerebellar granule cells", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the neurotoxin 14 (magi-1) family, 08 (Ltx-4) subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "CLGENVPCDKDRPNCCSKYECLEPTGYGRCYASYYSYKKKTL", "length": 42, "molWeight": 4851, "crc64": "909EFC583AB7A4FC", "md5": "8E2FC05F5973CBB01D5C3C92A0EE6646"}}
{"primaryAccession": "P20422", "text": "This is Plastocyanin protein, from Wild carrot, contains 97 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P20422", "organism_name": "Wild carrot", "protein_name": "Plastocyanin", "length": 97, "firstPublicDate": "1991-02-01", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "AEVKLGADDGALVFSPSSFSVAKGEGISFKNNAGFPHNIVFDEDEVPAGVDVSKISQEDYLDGAGESFTVTLTEKGTYKFYCEPHAGAGMKGEVTVT", "length": 97, "molWeight": 10181, "crc64": "B15DE6B8428F72D4", "md5": "9132EDFCD29C98569AE69A4A14782940"}}
{"primaryAccession": "P21745", "text": "This is Embryonic abundant protein VF30.1 protein, from Broad bean, contains 268 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P21745", "organism_name": "Broad bean", "protein_name": "Embryonic abundant protein VF30.1", "length": 268, "firstPublicDate": "1991-05-01", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEFAHLTVLSLFCLAFVGITATSSGEDYWQSIWPNTPLPKTFSDLLIPSGKTNSLPIKSEELKQYSTLFFEHDLHPGKNFILGNTNSVGSIIRPFTKSRQGVTDSIWLANKEKQSLEDFCYSPTAIAEHKHCVSSLKSMIDQVISHFGSTKIKAISSNFAPYQDQYVVEDVKKVGDNAVMCHRLNFEKVVFNCHQVRDTTAYVVSLVASDGTKTKALTVCHHDTRGMNPELLYEALEVTPGTVPVCHFIGNKAAAWVPNHTADNLCVM", "length": 268, "molWeight": 29757, "crc64": "906E129979E4ECB7", "md5": "ACE7038E9AC9F27ACD220D3AEB0DCA8D"}}
{"primaryAccession": "P25681", "text": "This is Acetylcholinesterase toxin C protein, from Black mamba, contains 61 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P25681", "organism_name": "Black mamba", "protein_name": "Acetylcholinesterase toxin C", "length": 61, "firstPublicDate": "1992-05-01", "FUNCTION": "Inhibits acetylcholinesterase", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the snake three-finger toxin family, Short-chain subfamily, Acn-esterase inhibitor sub-subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "TICYSHTTTSRAILKDCGENSCYRKSRRHPPKMVLGRGCGCPPGDDYLEVKCCTSPDKCNY", "length": 61, "molWeight": 6817, "crc64": "66625EF767341F3A", "md5": "6E2EDA5E453A6ABF0C624ECAAE0BD540"}}
{"primaryAccession": "P35476", "text": "This is Plastocyanin A'/A'' protein, from Common tobacco, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35476", "organism_name": "Common tobacco", "protein_name": "Plastocyanin A'/A''", "length": 99, "firstPublicDate": "1994-06-01", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "IEVLLGSDDGGLAFVPGNFSVSAGEKITFKNNAGFPHNVVFDEDEIPAGVDVSKISMSEEEYLNGPGETYSVTLSEKGTYTFYCAPHQGAGMVGKVTVN", "length": 99, "molWeight": 10451, "crc64": "88A24B3E00285698", "md5": "D7D4A5DAD280618E549CE1767A82A5F5"}}
{"primaryAccession": "P35477", "text": "This is Plastocyanin B'/B'' protein, from Common tobacco, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P35477", "organism_name": "Common tobacco", "protein_name": "Plastocyanin B'/B''", "length": 99, "firstPublicDate": "1994-06-01", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "IEVLLGSDDGGLAFVPGNFSVSAGEKITFKNNAGFPHNVVFDEDEIPAGVDASKISMSEEDLLNGPGETYSVTLSEKGTYTFYCAPHQGAGMVGKVTVN", "length": 99, "molWeight": 10358, "crc64": "3101896E0035E1FB", "md5": "985344F834716DCF7FC303F0F5488D4C"}}
{"primaryAccession": "P36103", "text": "This is Uncharacterized protein YKL023W protein, from Baker's yeast, contains 277 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P36103", "organism_name": "Baker's yeast", "protein_name": "Uncharacterized protein YKL023W", "length": 277, "firstPublicDate": "1994-06-01", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MNKEELLGFLLDDSIDSQKRCVTDQQAYSNWLKNDNDERTAHEESSSQSTIAALNKKKQTEAAQEDIEELLNGLEGIIGGADPRNLKSKSKRKTKKGGSKPREENVNTEKHIVMLEVEDFSDMSTHEDVNGASPSPNLDRSKKNEKRRKNAKELSYDELKDKLEVTTRKSRLECKDLKKKVHGLERRNLELEQRLEELKIENQTLIEINNKLLKNTNEDEINKSQRNKEKDRKRRERRTARRKDERKQEKKQEKKQDNKTSQSFPSSTDMNGQPIEF", "length": 277, "molWeight": 32293, "crc64": "01EAC7E4439171DB", "md5": "1591DEBD3D226457199F1A03D1218A0F"}}
{"primaryAccession": "P38292", "text": "This is Peroxisomal membrane protein PEX32 protein, from Baker's yeast, contains 413 amino acids, is membrane-bound, locates in Peroxisome.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38292", "organism_name": "Baker's yeast", "protein_name": "Peroxisomal membrane protein PEX32", "length": 413, "firstPublicDate": "1994-10-01", "SUBCELLULAR LOCATION": "Peroxisome", "SIMILARITY": "Belongs to the PEX28-32 family, PEX32 subfamily", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDTNSKTKVQTENKKIKAKFIHNHGQKPSLIQITPPMISSTLFHAYPLLLIFDNALANIMWLSDDKCLTFIYLTSIWLTISFFIPVETEASHFLPFTKILRLWLGIISGAFLFLSFMYYIVSLIASLRDTEPPTLDEIVVLLESVLDKLEVLRNELNVWKKLKLSFDGVNKECSGKRLFCRLFLFGTIFQIIIMRYISPGTYTRFFIITGLIYNTSSFQATLRLLWRFTAVRNFYYLGIESFKISSFLPKHLKMEQIIPLSQGRAITVPLVEVLPKLLRDKKGDDHIHILQLLLNEQKDNFGNEDLKILEIEVYENQRRWYQNKNWSTKLLPYERQNYCIEIKNTDGTLTMRSCLPPDGLGEEELPNNWHWINDNWDGTDWIYSDSAWKEIGQYSSLESFTRSRKWKRRLFHL", "length": 413, "molWeight": 48579, "crc64": "11671920832A91AD", "md5": "ED76C293E6FCA2DE170C949E06D76202"}}
{"primaryAccession": "P38745", "text": "This is Uncharacterized membrane protein YHL071W protein, from Baker's yeast, contains 532 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P38745", "organism_name": "Baker's yeast", "protein_name": "Uncharacterized membrane protein YHL071W", "length": 532, "firstPublicDate": "1995-02-01", "SUBCELLULAR LOCATION": "Golgi apparatus", "SIMILARITY": "Belongs to the LU7TM family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MDRTWLLLTWLLLLCGVVQGNQESINQKYHDVCSGMYSKEDFNGKVDPYISFTLEELSLADEDDDGEGVSVAVFDFQDYEHIGVRLPNGEIQYICDDYALDLGLCEDSSEGQFIIQETAIDPFTSKEHKLTSQILTFTQQELGTNDKVYSINKTGYYCVTTSSFISSSSKFKATVNFRNAYGQLDASEAYKMPIYAFLAVAYAVCTLVYSWLCWKHRHELLPLQRYILVFCIFLTADTIFVWMYYIIENQKGNSSVALHVYMVFISIFSAGKMTFTLLLALLISLGYGIVYPKLDRTLLRRCQIFAIFTFAVCVAFLVQKYSQNSESLSNLILITAIPLVLCLFAFYYLTLSSMNKTMTYLREQNQVVKLNMYRKLIILCYISLFILFLGLLVSTFAYVGMDTVDMIEQYWKTEFLITDTWPSFVYFLVFVIFAFFWRPTSTSYLLACSHQLPTDMENVSEFDLDDINSLSDEALPNREPRNDYQEHDHNMDIDLASDFEEVPSVNANTNANNDVLFDVDYDRDAKNDRSTT", "length": 532, "molWeight": 61206, "crc64": "EF2CB7CB74006503", "md5": "6AA3BBBF9ADB8074D7DD4ABF7F5D40D4"}}
{"primaryAccession": "P39996", "text": "This is Glutathione transferase 3 protein, from Baker's yeast, contains 337 amino acids, is membrane-bound, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P39996", "organism_name": "Baker's yeast", "protein_name": "Glutathione transferase 3", "length": 337, "firstPublicDate": "1995-02-01", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPTKSTFSRWKKADLIDLANKLEIDGFPNYAKKSDMIDYLESHLNHLEKPVDFKDDYPELRSFYESMTVDQSKDERNEYGSGSGNGSGSGSCDTATNDSDLEKAYIKEDDDEKPQSGDETSATKPLSSRNANSNAKTNFNLLDFSTDNDSSTSAFTKFKFNFQEYLSDIRYQTQKLNENVQDYLSTISAVDTIFSLLEFSFLVRNILAAGQPTSSSSLASSLEAAVAAHNKYQYTLDFCLPILTWLLFFRGIPTLVSYYINFIRYDLNIELDPMTFNLTKFLISLAIFKTCNNKNIDFHSFRCVNQLWTQLCTVNRSLGMVPLVFSMVSCLLTLYVL", "length": 337, "molWeight": 38235, "crc64": "E9F07EFD2A522006", "md5": "31B04236D4B8AC2C2A31559E2FBFEE84"}}
{"primaryAccession": "P40053", "text": "This is Altered inheritance of mitochondria protein 9, mitochondrial protein, from Baker's yeast, contains 627 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40053", "organism_name": "Baker's yeast", "protein_name": "Altered inheritance of mitochondria protein 9, mitochondrial", "length": 627, "firstPublicDate": "1995-02-01", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the AIM9 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIRYTVAGHSRRCVVGASKRVGAIKCITVAATKRFISNKPNEVFTKLTNDNDPKRDAFFKYTWGSWLKNDKQEKEKRFTKFSIEGLNRILNDIYIQSNEMAKAPDGKILPPVFNKNLTVSLVNNVVPKNIGKINPNEKVQVTTLSSIHEGKHHRIYKVDTNLNKAFILRIPYPLENENTLSYRIRSEVATMDFADLKLGIKVPKIFCYGVNSLNPVRQPFVLQEFIEGELLMKDWDPLIEDGSSNQKKYDNVIKQVSDFQSKLVSLKLNAFGSIYFNNDLKDGNEKEFVKEDIYDGETNPDLQNRWKIGPSVERCLWRHKSHLDFHKQMKPFLGPWPKKSPMDIIKNTGLLEAENAKTRIAMKEAGSSAELMYPRTLKEQITTYENLAKIAPDLFNVKTKAIPNMQELLSPRLFHPDLDPMNIIVNKEAQEAYLLDFEGACTKPFILQNSPQFIAYDGPKIYDLKEDITDFDKLSEAEKVQYQFMYKRTRNQHQWEKKLNDNNPKLITAVAPPVKLLRSPYIAAVERKTEEEYLLIDESLLQLKEVWDIFAQNELVNQKKFPLNYSKEDIERHVEDLQKLHEKLISTPFAATQGWIPQDMFDQLLNSGSIVKQENGDYTVKQPEATK", "length": 627, "molWeight": 72414, "crc64": "395479DDEC0F4F51", "md5": "64583486C8732D7A741A4C5BF3FC3898"}}
{"primaryAccession": "P46998", "text": "This is Mitochondrial membrane protein FMP33 protein, from Baker's yeast, contains 180 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P46998", "organism_name": "Baker's yeast", "protein_name": "Mitochondrial membrane protein FMP33", "length": 180, "firstPublicDate": "1996-02-01", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLYTRLLRHNSQFTKFSGTSPNLGSKPLFSKGNLYTSLLVTTLYGTGLACLYLESNSLNKSKEQEDPHAIAEDDIVNIVHDAPNRIFKPALDTYQEKELDLQKSDLHKVLHSLTYSDVSQFSIVWGFLIQLSSLIGNSTLGKKSILYKGSVVSVLGFPPLIYMALKLRMKQLEKAGVRFE", "length": 180, "molWeight": 20185, "crc64": "F4F53250CF0C6F0B", "md5": "167B7A6E98727BA1E72EC7306F016E93"}}
{"primaryAccession": "P53747", "text": "This is Uncharacterized vacuolar membrane protein YNR061C protein, from Baker's yeast, contains 219 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P53747", "organism_name": "Baker's yeast", "protein_name": "Uncharacterized vacuolar membrane protein YNR061C", "length": 219, "firstPublicDate": "1996-10-01", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLKLTTTSVTFHVLRYFQLGLSVTNLLLASFAIITNYKVDRILRLSLAVSIISSVYFGIVRFLPVLLIFVMEIVQTVLWFTAFVTLASKFGSMSCSSMPRGINFDYSGSCKIAKIDILPEAVLFILFLATTYASYITVLSQAKENGSSTRSVLKACVKALRDTVDRLETSLEESEPLLDLEVQEDARTETESIEDSTDSEDNANIEQEKVIDGSIEHSS", "length": 219, "molWeight": 24317, "crc64": "744FABCD688BD3FC", "md5": "0D335144AA33F1028E1890AF8C4010DD"}}
{"primaryAccession": "P82953", "text": "This is Horcolin protein, from Domesticated barley, contains 146 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P82953", "organism_name": "Domesticated barley", "protein_name": "Horcolin", "length": 146, "firstPublicDate": "2004-04-13", "FUNCTION": "Mannose-specific lectin, Has a weak agglutinating activity against rabbit erythrocytes", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the jacalin lectin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSKPVKIGPWGGNGGSERDVQPKPIRMVSMTVSSGAIVDAIAFTYVGTDNVQHSSGIKWGGTGGTEDTINLDATNYVTEISGTVGKFGTDDIVTSLKIITSKGVTRTYGSGTGIPFRVPVLDGGKIAGFFGRAGAFLDAIGFYITP", "length": 146, "molWeight": 15122, "crc64": "E5417043C6FCA0A8", "md5": "8CE1BB2DC95810EE7203E9966D517D01"}}
{"primaryAccession": "P83553", "text": "This is Dermatopontin protein, from Bloodfluke planorb, contains 148 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P83553", "organism_name": "Bloodfluke planorb", "protein_name": "Dermatopontin", "length": 148, "firstPublicDate": "2004-05-10", "FUNCTION": "Seems to mediate adhesion by cell surface integrin binding", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the dermatopontin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "AYINLPGQPFDFQCPAGQVISRVSSVYDVLLEDRQWEFGCRTENVTQTCSTSGYANDFGLPLSYSCPGKKVLTGIRSYHDNQIEDRRFTFRCCDVMSKATTGCHVSEQVNQFNGPMLLEVSAGQAIKGAISQHDVAFEDRVWKFKLCK", "length": 148, "molWeight": 16602, "crc64": "F04CEFC42A01DBD2", "md5": "F270A79153151DB166C67A3536F24BA0"}}
{"primaryAccession": "P84338", "text": "This is Plastocyanin protein, from Ginkgo, contains 99 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P84338", "organism_name": "Ginkgo", "protein_name": "Plastocyanin", "length": 99, "firstPublicDate": "2005-10-25", "FUNCTION": "Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the plastocyanin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "VEVLMGGSGGELAFIPNELQVNAGEQIVFKNNAGFPHNVIFDEDAVPAGVDVSSISMSEEDLLNAPGETYVVKLDKKGTYRFFCAPHQGIGMSGIVTVN", "length": 99, "molWeight": 10500, "crc64": "16406415A9F3C53B", "md5": "AF8B0653EDF2559224B32096EAC270E4"}}
{"primaryAccession": "P86038", "text": "This is Raniseptin-3 protein, from Chaco tree frog, contains 79 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86038", "organism_name": "Chaco tree frog", "protein_name": "Raniseptin-3", "length": 79, "firstPublicDate": "2009-05-05", "FUNCTION": "Has antibacterial activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Dermaseptin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGIVSLSICEEEKREGEEEEKQEEENEELSEEELRERRAWLDKLKSIGKVVGKVAIGVAKNLLNPQ", "length": 79, "molWeight": 9074, "crc64": "6A694938DCCB3421", "md5": "43E2E149228D75AD6AB058407063D18A"}}
{"primaryAccession": "P86188", "text": "This is Raniseptin-8 protein, from Chaco tree frog, contains 80 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86188", "organism_name": "Chaco tree frog", "protein_name": "Raniseptin-8", "length": 80, "firstPublicDate": "2009-05-05", "FUNCTION": "Has antibacterial activity", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the frog skin active peptide (FSAP) family, Dermaseptin subfamily", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MAFLKKSLFLVLFLGIVSLSICEEEKREGEEEEKQEEENEELSEEELRERRALLDKLKSLGKVVGKVAIGVAQHYLNPQQ", "length": 80, "molWeight": 9203, "crc64": "C36A69538FDD0E81", "md5": "0780AB2FCF76CD481452CB2C92F47A1A"}}
{"primaryAccession": "P86947", "text": "This is Valine-rich protein protein, from Silver-lipped pearl oyster, contains 238 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86947", "organism_name": "Silver-lipped pearl oyster", "protein_name": "Valine-rich protein", "length": 238, "firstPublicDate": "2011-10-19", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQAVLLVVALFGAALADPPKKIHLPTPKVKRVEKLAHQEHGVNVVQAVPITKTVVRTVNVPKTLIQEVPIHVYTDLVLKSPVPRRKVIDIKKTVLQPHIRHVPVDQPYVVHRKVPVIHTKIVRQPRPVPRIVNIPRLKVVQKQINRIIDVPRLVTRERVHRVIKPVPVVRTRVQHVDVDVPMRVVVPEPVVQDRHTQSVETVPVPHDVVRKVKVPKTFVLKDLIPVPEKAGRHYSSDK", "length": 238, "molWeight": 27079, "crc64": "99E2D02ECD3A76CB", "md5": "F9360B075987DA657CB43D9197CD1822"}}
{"primaryAccession": "P86957", "text": "This is Serine, glycine and glutamine-rich protein protein, from Silver-lipped pearl oyster, contains 329 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86957", "organism_name": "Silver-lipped pearl oyster", "protein_name": "Serine, glycine and glutamine-rich protein", "length": 329, "firstPublicDate": "2011-10-19", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKTVLLFVVLVGLAYCDDDGWDMGNFFQQYHQWQQQISSSSSSSSSSSSGGGGSSGGGASGGGGGSSSGGGGASGGGGGGSSGGGGLTKVVLKAGGGGGGGFKSVGGGRGGVTKLVASGGASGGGSVSGGGGGSLALLAGGSAAGGGRSGVVTVSKQPIIINRQVTHVNTGGSGGGVGGGFGGGRGGFGYGLYGGYHHYNPCGYGQVYSYYYGCQSIYKQPARQVYHQPVYQPVQTVHQPVQYYQQPYQYQHSYGQPSYAYQPQTTKYISYSYPQYSSQGSYPTVAGGSAGGFVRGSSGGMGFSSGGIGGHSSYPLSVFKHAKGEKYKL", "length": 329, "molWeight": 32486, "crc64": "EDCF34FEE84E873B", "md5": "D6D80EB141C428D4CD550A7AF2A475C1"}}
{"primaryAccession": "P86965", "text": "This is Uncharacterized protein 3 protein, from Silver-lipped pearl oyster, contains 98 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86965", "organism_name": "Silver-lipped pearl oyster", "protein_name": "Uncharacterized protein 3", "length": 98, "firstPublicDate": "2011-10-19", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKYVALAFVLSLVILQISAQVGAAYIPGMGLGSVGRTGAVAGASAGVGNQGRGAGILRLLSIIMELVKNNQQAQPKQDTFGAQLQSLLKKKMILEMIN", "length": 98, "molWeight": 10198, "crc64": "B8FAE520C4E9CC23", "md5": "F6C42A28E211CEB849A481537CEF226D"}}
{"primaryAccession": "P86987", "text": "This is Insoluble matrix shell protein 6 protein, from Japanese littleneck clam, contains 183 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86987", "organism_name": "Japanese littleneck clam", "protein_name": "Insoluble matrix shell protein 6", "length": 183, "firstPublicDate": "2011-10-19", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLEIALLLLAVTVCVKGGFLQGRSGYDCRRRCGYDRRYVCSTDGTTYDNECMMKCNWAYKSCDGRCPCYRSPAPVVYRPKPAVVYKPRPVVNYEPASVNYEPASVNYEPAAVDYPSVPDYEPIPVYNEPAPVYYDVPVQSDCVCSKDKDYVCTYDGETYDNECEANCDGKAKMCDGQCPCSK", "length": 183, "molWeight": 20553, "crc64": "DE6BA5DA5610C683", "md5": "24491E767073A90CB62D6E6DC04BE1BA"}}
{"primaryAccession": "P87122", "text": "This is Putative cation exchanger C3A12.06c protein, from Fission yeast, contains 743 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P87122", "organism_name": "Fission yeast", "protein_name": "Putative cation exchanger C3A12.06c", "length": 743, "firstPublicDate": "2008-02-05", "FUNCTION": "Putative cation exchanger", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2,A,19) family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSKTSCFLKKYRLILLWCILGIAYILFWTHRISKAFASVSSTSDSTVHLFERGNTLNDSNDQILLTCNDIKNITPANQCRFAKAYCKGEASGFFDYVEFYFCTINSLRFPVLSIIVGWLIFLFITIGISASDFFSTNLVTISWLLQLPDSVVGVTFLALGNGSPDILSTFAAVRVNSGGMAIGELLGSAFFIVAIVAGSVCLIKPFKIPRRHFLRDVAFLTGTILLVIMFVLHDGSLSIWQSLVMILYYLLYVLFVFFSGSSGVSVVITDENYLPVSLPVYSPVLNSFDDSDSYSSTDSELSEEAFLLPAQASRKTQKIHYINDNDPSNSYSSYQHSHVHDFIHKNNTHSNRVLSQSSGPIVRPSLLAALDFRSSNEEQHPGLRSLDPLNIQDGDLTMHPMHIRHSQSDFYPSGINTPVSGINYPNLGFSANNSVQSLVSEIFRHPTHTDEDFPLPSPSLSSLLFPTLRNFAKKSWYEKLMDVLAVPSVLIFTLALPVYQCPRLAVDPIYHMDVSNCNPSKPTWSRKLRLLQCVFVPFAFVTFSITGGNRLYIYAASSVFSILCITALYYYTDEEKPPKFLPWVSFIGFVLGIIWISTIANEVVGILRALGVIFNLNESILGLTVFAAGNSLSDLIADIMIARSGFPEMAMGGVFGGPTLNILIGIGISSFYSSISNHGNDSVIEIPHSLSITAYFLLACLLLLLIYVPLNRFRVNRVLGLLLFILYIVGTSTNIVVELLKDK", "length": 743, "molWeight": 82397, "crc64": "15B5FD26FACF8BB8", "md5": "905904A3C123EA8E0732E0A6CA01BADF"}}
{"primaryAccession": "P87143", "text": "This is Uncharacterized RNA-binding protein C57A7.13 protein, from Fission yeast, contains 565 amino acids, has 1 RanBP2-type Zinc finger, has 1 C2H2-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [153, 184], "description": "RanBP2-type", "keyword_description": "Zinc finger", "textural_description": "RanBP2-type Zinc finger"}, {"location": [404, 429], "description": "C2H2-type", "keyword_description": "Zinc finger", "textural_description": "C2H2-type Zinc finger"}], "meta_data": {"primaryAccession": "P87143", "organism_name": "Fission yeast", "protein_name": "Uncharacterized RNA-binding protein C57A7.13", "length": 565, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"RanBP2-type Zinc finger": 1, "C2H2-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKDYYSENGFEEIFEEKGSTSSNISDNCASRDYDVNISSDNPRLLDSYRPKGNYGRDRNSPLSRHIGVPNQEIILQGLTPEILEEHIELALYATGAKVSTVTLIREKETQKSRCFAFAKFVSLQDSKDWMEANFPTLVIDGIDVSVRFSRAAREQIEGWCCQNCDILNYSYRESCFKCRVPRNQASIAIGNHKISKRNGDMDVSDVPSVYLILRNLDRSLSEETLWKGLSKLEIDVQRVFMIRYKFNDAFCGYAILEFKDVDESAKALMKARTYPGKGFTLASRKVSVDYIHDGVLIPAYTESARWQFPTKTGYLVYWDPELYCSIYVPEGIDTDQFKPIEVNKKPKKEKRARSSNYIDVPASKKVATSLQRWNDAQKELKDNIPDLSEEEEKLLLHFVWKSALICVLCERKFQSWGHVVKHITQSIMHNNNLKNHELVSSAELLMHRVRQTESVDYRDRATERRIVPAASSDTIVEAKKSSQGSSFHSTSNVSMKMLNSMGWNKGSGLGTNENGIKEAIQPTMYLPGVGLGNKGSKIQINMTPVDRVKDRARSLYFQNDKNNNL", "length": 565, "molWeight": 64416, "crc64": "3D11854C7058C654", "md5": "310595ED953C9B95A48947CD22B69F18"}}
{"primaryAccession": "P87232", "text": "This is Large ribosomal subunit protein uL29m protein, from Fission yeast, contains 144 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P87232", "organism_name": "Fission yeast", "protein_name": "Large ribosomal subunit protein uL29m", "length": 144, "firstPublicDate": "2009-05-05", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL29 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRSTLASAQKAAVRIPKGFVFPVPKVKSAPKVSDTHPLWNFFRDKQALPPPSEEAKFGRAWAAEELRWKSFNDLHGLWYNCLREKNLLFTQRAEMKRLQLTIPKASNERVLAVNKTMAAIKFVLWERQRAYTSAKQLEKQKGSS", "length": 144, "molWeight": 16586, "crc64": "FBFBBDB100E16583", "md5": "D80054A3D4FF56C6D4D074C979AAD3A6"}}
{"primaryAccession": "P87299", "text": "This is Meiotically up-regulated gene 74 protein protein, from Fission yeast, contains 285 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P87299", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 74 protein", "length": 285, "firstPublicDate": "2002-12-13", "FUNCTION": "Has a role in meiosis", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKKHKSSIKCFKIDQISQQPETDLVFTKRSECKVKDELFSDKENSILCKQLKELDLVVSSNKEFLNEKTSDQISFLKPRETVVEKKLANGSIWPNETSHLDKSRDLSSHSNGLDALAMTPYIVKENNKTHLSPRGNYPSEAEKSCDFYGQPLHFYRENTSPCLYGSSLSNVFTEKSSDYRHGLGSPTSLVSSNTASKLHLGRKDIVKLSELRNCINSSKDSNQIQELENLLRKEKQRNTEHEKIIRRMKKELKELHSQFNFAKKLFISALSANQDILDKMNDEFN", "length": 285, "molWeight": 32723, "crc64": "BE0E40EE33B10476", "md5": "210DEDAEA6F74702C7E6004D4DCC515B"}}
{"primaryAccession": "Q02873", "text": "This is UPF0651 protein YPL107W, mitochondrial protein, from Baker's yeast, contains 248 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02873", "organism_name": "Baker's yeast", "protein_name": "UPF0651 protein YPL107W, mitochondrial", "length": 248, "firstPublicDate": "2006-05-30", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the UPF0651 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIRNQGWSLLYRIYPVRRFTRYSRVDMTFEGNTQDISTSVEERMTTVFGGRLKGEPPRSTSRVLSGGTKKIAGVQVPAKPQEPDNCCMSGCVNCVWEIYSEDLRDWKHRRKEAAEKIAGTKEKWPKDWNPPLGLLHMENVPVELREKKLETDSKKAEQPHDLSAIRSLFPKRKGPLPKSVLAAKRKNIALRHNYEQKDGGDQSVSESDADEGWEDIPVYVKAFAEFESKKRLQKIRRQEEIKKRTALV", "length": 248, "molWeight": 28570, "crc64": "5FCBD2A6F84EA826", "md5": "D0A11F6D9D4AEBC18374F6B97EFCC945"}}
{"primaryAccession": "Q02981", "text": "This is ABC1 family protein YPL109C, mitochondrial protein, from Baker's yeast, contains 657 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q02981", "organism_name": "Baker's yeast", "protein_name": "ABC1 family protein YPL109C, mitochondrial", "length": 657, "firstPublicDate": "1998-07-15", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the protein kinase superfamily, ADCK protein kinase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSFLKFAYRNSWRYYSKSTRHFHKIPIRQFIIPTSIAFYLTQNSFPKQNCLIYNDSLKPDPKGDTFEMGLYVSSENELQEKLKSFRSAKITESRNKLIRYLRIFWFGFNDNIVEPVCTILRFLEISAIFLPLLLLYPISWFGHKLKITDTNITETRGSLIWCQLLRKALELAGPSFIKLGQWAGSRTDIFSHALCHELGKLHSNVTAHSLSFTLEKLSQALKVDKIEDAFDEFNRTPIGVGSIAQVYVGELSQKYIDKYDNIQIGKDGNRWCAIKILHPNVRSQIRRDLKIMKFCADAINWIPTMEWLSLPSEVDQFSILMNIQLDLRIEALNLERFNENFKNSIQVKFPKPFLPLSNRDVMFEEHVYGLSMEKFLSTKKQINDVELCKKVSDPFVDAFLQMLILDDFVHADLHPGNVIIRFVKTNKYGTNIISSELESYRITHDLRKKIEEDQDQDFVGKLKSVLTNYTPQICFIDTGIITELNEKNRINFIALFNALARFDGYRAGELMIERSRTPETAIDKEVFAFKVEKLVDKVKQRTFTLGTVSIGDLLDQMLSMVRSHHVRMESDFVSVVVAILLLEGIGRQLDPNLDLFESSLPILREFGFKREAKSLLKDASTLSMLKIWVGLEVRQLMHLSMKQIYDLVRTDQLCPNY", "length": 657, "molWeight": 76176, "crc64": "6814CE70DBE2B97C", "md5": "EEF0BBF1732826AE2AC8732C8FE0EC62"}}
{"primaryAccession": "Q03482", "text": "This is Cysteine-rich and transmembrane domain-containing protein YDR210W protein, from Baker's yeast, contains 75 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q03482", "organism_name": "Baker's yeast", "protein_name": "Cysteine-rich and transmembrane domain-containing protein YDR210W", "length": 75, "firstPublicDate": "2006-10-17", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the CYSTM1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSQQQGYYQQGPPQQGYYQQGPPQQGYYQQGPPQQGYPQQQPVYVQQGQPKEESCLDSCLKCLCCCFLLELVCDN", "length": 75, "molWeight": 8571, "crc64": "B74A67469B8ECD16", "md5": "697177DCBC71AAAC80DD9DDA3DBFFC58"}}
{"primaryAccession": "Q04231", "text": "This is DNA repair protein RAD33 protein, from Baker's yeast, contains 177 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q04231", "organism_name": "Baker's yeast", "protein_name": "DNA repair protein RAD33", "length": 177, "firstPublicDate": "1997-11-01", "FUNCTION": "Involved in nucleotide excision repair (NER) of damaged DNA, Required for the repair of RNA polymerase I-transcribed rDNA and RNA polymerase II-transcribed DNA regions, May have a role in stabilizing the DNA repair proteins RAD4 and RAD34", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSKSTNVSYERVELFENPKVPIEVEDEILEKYAESSLDHDMTVNELPRFFKDLQLEPTIWKLVRNEDVIIEGTDVIDFTKLVRCTCQLLILMNNLTVIDDLWSMLIRNCGRDVDFPQVALRDHVLSVKDLQKISNLIGADQSSGTIEMISCATDGKRLFMTYLDFGCVLGKLGYLKM", "length": 177, "molWeight": 20270, "crc64": "23BAE68F510EED31", "md5": "38329A1D537FFFF3E9D832ADE26EB29D"}}
{"primaryAccession": "Q05812", "text": "This is Meiotic sister-chromatid recombination protein 3 protein, from Baker's yeast, contains 728 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q05812", "organism_name": "Baker's yeast", "protein_name": "Meiotic sister-chromatid recombination protein 3", "length": 728, "firstPublicDate": "2005-11-22", "FUNCTION": "May be involved in the control of meiotic sister-chromatid recombination", "SUBCELLULAR LOCATION": "Cell membrane", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MVFGFTKRDRRVPDLSRYDYYYQNHEDYNKSPQLSAAAASAASAASPDRTNYSRSHSLVSHAPSIPRQRSSVKSPGRRLSTSSAAPPTSRAAAKQYSQKTYSLRSQRSGEYHLHPPGYTTNGSRMNSMTSGANVRRNYGKNKSTAGNNNDSRANSITVKTTQVTDPSGRTQSITKKTIRKINGYEYVETTTTTKNLVPLGDSQRHFDEFSENYMLQDDDILEEQASDNIHDIIEENETDNEKPYSPVSESHLQDDSELNVEKPDFPLGSYFHHKYSTDVMPLEEESSLSNFSDALDYIPPTHQTSSKYIHNKRKQASTTRRKKRPPAVKNAEAEAKKPLTEAEMYLKALEVAKRNVYHTDAASDNASAPLGSNKSRKSRMGQKMTLRSSSDSPTATANLVKSNVEVQPKRFTSSFFSRNTKSAPHEVHNHSVSTHFKSNKAVDPVPEPKSANTGLTDKEMYDQALKIAQARYYNSHGIQPEAVDNSTTAAKPRQVGVSHLGSTGSIPPNEQHYLGDSEIPVQSEVHEYEPIPLQKTKTTGSSKNKFKTMFDKVLQFSQENYGYQHKKEQGEQTPVTRNAEESFPAASISEGVTTAKPSSNEGVMTNPVVTDSPSPLQQQIDSTTASSNGQSQGNVPTSAVASTTRTRSPELQDNLKSSSSLLQDQTPQRQEDATDPTTSSTNELSAAEPTMVTSTHATKTIQAQTQDPPTKHKKSSFFTKLFKKKSSR", "length": 728, "molWeight": 80530, "crc64": "1962D638DB602B71", "md5": "310CEF6DA4990D28AD17B70127660EFF"}}
{"primaryAccession": "Q06139", "text": "This is Citrinin resistance protein, mitochondrial protein, from Baker's yeast, contains 101 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q06139", "organism_name": "Baker's yeast", "protein_name": "Citrinin resistance protein, mitochondrial", "length": 101, "firstPublicDate": "2006-07-25", "FUNCTION": "Mitochondrial protein that is involved in citrinin resistance", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MQSISNCPIGLVSKNTINSASTIAEWVACPWKYINVVGSGRYVSNKPDKITRYDLLKAAQEAEMQELLTRNDMKGRHKRNKKSKIALETIAEENSSTESLF", "length": 101, "molWeight": 11348, "crc64": "0662D0D991616587", "md5": "153CF91985B1F00591EDA41E6B7A9E96"}}
{"primaryAccession": "Q09774", "text": "This is ATP synthase subunit g, mitochondrial protein, from Fission yeast, contains 118 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09774", "organism_name": "Fission yeast", "protein_name": "ATP synthase subunit g, mitochondrial", "length": 118, "firstPublicDate": "1995-11-01", "FUNCTION": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain, F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk, During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation, Part of the complex F(0) domain, Minor subunit located with subunit a in the membrane (By similarity)", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the ATPase g subunit family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MFSTSRIISRINYNFLRKSHYSTKTVAEQAKGRFTPLIQKLSAVQQPIMYWANVSKELVQQVYHSQKIAPPSNTHSPFLFWKSQSSEAWGRNFFIAVEIVGIFCAGQMVGRRKITPYH", "length": 118, "molWeight": 13640, "crc64": "7674DCF4BCB6D721", "md5": "AEB951EDA9FB87E633DF41CD38B34FCA"}}
{"primaryAccession": "Q09800", "text": "This is Uncharacterized protein C22G7.07c protein, from Fission yeast, contains 419 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09800", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C22G7.07c", "length": 419, "firstPublicDate": "1995-11-01", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the MT-A70-like family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPCILYMDDTSCLIDLPTSLQFNKHILPTRTKPVVKPYLLPEKSTSDYENSGKGTVGQVLQSLQRVRRALQLRSLDDNQSTDKSHHVQFQDIVYRSNTSASEIHFQAENAPLVQWYSDIFKVLVKAPVIQFEDQCLQWLKMLNTIPPSYSFITIKSKDTVELGLEEIYQQCVQNDGASAIKLKLKGSKVITESSETNCRDSIYYIPARSSFIMGDVEKTAQILLEAIDGHLEKPKCIIIDPPWPNKSVARSSVYKVNRNLGYLKALPIQESLSKTGVVAVWCTNKEKYVNFVKKVLFKKWNLTLVSTWTWLKITAFGEPLFDVYSNMRKPWEQLLIGVTSEYTSVYSDKIPPTFTIIGIPDYHSRKPSLKPFISRWFNCSANESLPVLEIFGRSLTPNWITWGREPLLFMHELYWSSDN", "length": 419, "molWeight": 48052, "crc64": "ED7D824A09B390B4", "md5": "456C2F42F813DB5EF446CC325FAA4EDB"}}
{"primaryAccession": "Q09LL3", "text": "This is Bifunctional nuclease protein, from Oryza minuta, contains 331 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q09LL3", "organism_name": "Oryza minuta", "protein_name": "Bifunctional nuclease", "length": 331, "firstPublicDate": "2012-10-31", "FUNCTION": "Bifunctional nuclease with both RNase and DNase activities, Involved in basal defense response, Participates in abscisic acid-derived callose deposition following infection by a necrotrophic pathogen", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the bifunctional nuclease family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEIINGPVLPRYAAPATGALTSDAKISGQLLRRVHLRRRACGLQGDHYRAARRFFGFPSERHARSGWVWPVYCSYGSSSDGDGAAAADYDASGEEFVNSSVMEAVELRSVSDGFVIKMRDGKNLRCVQNNPRVLRLRDSAPHHAIVLKMEDGSDLLLPIIVMETPSIMLLAALRNIRIPRPTIYNVVKEMTERMGYAVRLVRITEMVHDAYYSRLYLAKIGNEEETISLDLKPSDAINIAFRCKVPIQVNRRIAYNNGLKVVQPTPSESYVSSDQFQYTRLDRPDDQPCFEAQEFDLVRNMLVAAVEERYKDAAQYRDQLFMFRAKKKNMI", "length": 331, "molWeight": 37587, "crc64": "952C43FB459A9C40", "md5": "BE2CAAB1907DD883FA3C09657A7F0800"}}
{"primaryAccession": "Q10215", "text": "This is Putative thiosulfate sulfurtransferase, mitochondrial protein, from Fission yeast, contains 142 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10215", "organism_name": "Fission yeast", "protein_name": "Putative thiosulfate sulfurtransferase, mitochondrial", "length": 142, "firstPublicDate": "1996-10-01", "FUNCTION": "Thiosulfate sulfurtransferase which catalyzes the transfer of sulfane sulfur from thiosulfate to cyanide", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFSKTLSVSRLLMTRSFYSSTVVKNVSIFDFEKVYNLSKRPTGDKSTVLIDVREPDEFKQGAIETSYNLPVGKIEEAMKLSDEEFSKTYGFSKPVFEDNVVVYCRSGRRSTTASDILTKLGYKNIGNYTGSWLEWSDKIKSK", "length": 142, "molWeight": 16185, "crc64": "DF408B3E5D5E994E", "md5": "F6C48E0DE6D0AF122A4C8D4C9BFF9965"}}
{"primaryAccession": "Q10253", "text": "This is Meiotically up-regulated gene 64 protein protein, from Fission yeast, contains 286 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10253", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 64 protein", "length": 286, "firstPublicDate": "1996-10-01", "FUNCTION": "Has a role in meiosis", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "METFKTHITGQFNATVSSITPFAKKTTHYLRTKIGSRVEELSLPEDYVELEQQVDSLKEAYNLVLPIVETVEVDGYDYPTNFRDSITDFGKTVSGKVRNLGNLTPLEQTPLASVGKNLEEKEAAAKPSRTLYNAISRAASEATTKMGAGNPLSSAFGQISVLEEKVGNLQGERDSAISKNFCEQVRAVLYPRFAEAHRVKADVQDKRLQLEMAKLDVESAKPENLEHCKSAVRSAEDELNGAIEHAKILYEQILNKDYNTDLLRSIIKNQLKFHQDAAAALSDITI", "length": 286, "molWeight": 31748, "crc64": "2EC915AC7CED234B", "md5": "D780DE5D0CBD8919A437FC0C844C6EBF"}}
{"primaryAccession": "Q10308", "text": "This is Meiotically up-regulated gene 43 protein protein, from Fission yeast, contains 269 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q10308", "organism_name": "Fission yeast", "protein_name": "Meiotically up-regulated gene 43 protein", "length": 269, "firstPublicDate": "1996-10-01", "FUNCTION": "Has a role in meiosis", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNNITRDIYTKGQPADLKRLLMKRNSFRRPLLNMRCNSVLQYSLEKRKLTVQDLKDTRMELNNMIRILTEAMAAHEWTVDNVNIADIQSLQSTIHSTLKNFQKINVLQLNINASDNSLAYLSKPEESYNFLTIYFSTLLSYEKVENLIKKSLTVIDSLYGLLNYQINAQHSLGCIPLNQDSFKQLKLLICILEEDIKLDDCGLEISASKNEYLEKIKTHYKTWLRIHTFLTLFPVPSVLSSNLKKQMYGWFEDLRDESLKSIILASLSE", "length": 269, "molWeight": 31234, "crc64": "0C3DF87A138CA5BE", "md5": "9AFFAEB7A9F68B39319BF691A0F82DF3"}}
{"primaryAccession": "Q12032", "text": "This is Altered inheritance of mitochondria protein 41, mitochondrial protein, from Baker's yeast, contains 185 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12032", "organism_name": "Baker's yeast", "protein_name": "Altered inheritance of mitochondria protein 41, mitochondrial", "length": 185, "firstPublicDate": "2006-05-30", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the AIM41 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFRQSIRPLVSNRLTFIRYNSSPAYTAAVSLLKGDLKKAMIAKDEMKKTAIRNMLSAIKNKEIALKGKSADEYSLYDMYSKLISQRKDSINEFLANKRDDLVAKEQGEMDIIKKYMDQLPVSSELDIDQNVKKLLDALKTKAGEKKVQIKEIMGEIDWKSLPTEWKTSPTAIKNSIVKQFKEIFK", "length": 185, "molWeight": 21229, "crc64": "B91B6300805A6E55", "md5": "A58E182C9DCED7855A80BBE59691A77E"}}
{"primaryAccession": "Q12129", "text": "This is Nonsense-mediated decay protein 4 protein, from Baker's yeast, contains 218 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12129", "organism_name": "Baker's yeast", "protein_name": "Nonsense-mediated decay protein 4", "length": 218, "firstPublicDate": "2005-11-22", "FUNCTION": "Involved in nonsense-mediated decay of mRNAs containing premature stop codons", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTQYNFIIDASAFEKGLGNIKRWCSDCTEAVTLNFYIPTFTLNELDFLQQRRKSFAARESLKFIDRLDDSKFANLKVFIEFPEVLDIILWSDVMEHNDSSGKINIAKLPKRLKNLLKSCIYKCYLEGNEGLHWFLISEDPQIREMAMQCNIPSCSIVDVDSILSKDMNDKSFRESEKFNNMMLKNGTKEESENGREIIRTNFNKTVYASRGTGELWSP", "length": 218, "molWeight": 25286, "crc64": "ABB44FD0C5CBB4C7", "md5": "CFBA71DF6904B390B166068B2DDCEF07"}}
{"primaryAccession": "Q12134", "text": "This is Protein HUA2 protein, from Baker's yeast, contains 243 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12134", "organism_name": "Baker's yeast", "protein_name": "Protein HUA2", "length": 243, "firstPublicDate": "2007-01-09", "FUNCTION": "May have a role in actin patch assembly", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQQTKFGKMYLDHDSVVEYSEDEIVEADRITLGYKKRLSMIENQMRHLLEDFSLDVQQIEPILADLQKYYDAFLQLLQKRNKSLQCKRSTHQPVPSPMNSQTSTNAKVNLSGKLMKFQLNSVQKFDEENILRILQNKIEFEHYFQIDKGKKQKVLLLAVYQCLNGPTRLHKVLNIEGIIHNNSIRTILGKQVSSSKWTVFLYDVKLVLLAHRQDVPNLETSKMIVRYGDLFPCALYFKDHTAY", "length": 243, "molWeight": 28414, "crc64": "B1F3A81B7C0F65AC", "md5": "416A7E6E9EBFDE0EB5471F81EF5B2271"}}
{"primaryAccession": "Q12346", "text": "This is Uncharacterized membrane protein YPR071W protein, from Baker's yeast, contains 211 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12346", "organism_name": "Baker's yeast", "protein_name": "Uncharacterized membrane protein YPR071W", "length": 211, "firstPublicDate": "2006-10-03", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MQNGTEDKSNIPARSNDDVLPPLAVRLTMKVMRLIFIGKMFAYSFVPFPPFKLLTFDNTVGWFVAYSAIVSIWGFAVWMERGYRHKINLLPPRCTKIRCSRCNTRIRSPNWFKYKNWLYFFLLYVSLTTSNLIIQLASFMTEMSRRGISVPGTKDPGKRDYLGLIIPMRFIGAFIHYMTANLFKEYYLHNGPLEKNDRPSTDEKTSENETL", "length": 211, "molWeight": 24606, "crc64": "975803A6E2AB773A", "md5": "5A4C001169FE85F89BC1F26945D6FE29"}}
{"primaryAccession": "Q12497", "text": "This is Protein FMP16, mitochondrial protein, from Baker's yeast, contains 93 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q12497", "organism_name": "Baker's yeast", "protein_name": "Protein FMP16, mitochondrial", "length": 93, "firstPublicDate": "2006-06-27", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MLRTTFLRTPRQLMRKSPRASFSIVTRAAFPHLKNNQDEAEKKEQGLFDSNKKRLDTLEHGKNPDYKQPGMEDLKKKGDDARIEQNRPDDGVY", "length": 93, "molWeight": 10845, "crc64": "CD7CF3AEF9ADB044", "md5": "5858D844BAE118BCDBED9AE74BDFDABB"}}
{"primaryAccession": "Q1T7F1", "text": "This is Putative chemokine-related protein B42 protein, from Human, contains 81 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q1T7F1", "organism_name": "Human", "protein_name": "Putative chemokine-related protein B42", "length": 81, "firstPublicDate": "2013-05-01", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPLSDWCCGICEEAPLGRAYTQTWMETGCGPHGVTALGQQELKDCLRARSGGTASSVDWIMEAARGSLNVHNCLIKFGRRD", "length": 81, "molWeight": 8815, "crc64": "76B7D8F1DCAFA2BF", "md5": "7591E3E3BF5BA2F005C0E885B75E7E9B"}}
{"primaryAccession": "Q24JJ9", "text": "This is Nuclear pore complex protein NUP43 protein, from Mouse-ear cress, contains 361 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q24JJ9", "organism_name": "Mouse-ear cress", "protein_name": "Nuclear pore complex protein NUP43", "length": 361, "firstPublicDate": "2014-11-26", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEMMQDSFQVHRIPQSKYVDGVRWLPQASALNRFFATASYDADCDSSSIEIQSLDPNPRGNHNTNPLIESLSSWTSPSRVSSLEVAGNGGGGGSFKPMVSAATSSGSLHVLMIDLVEGAAIEEFYAAEGERFHVGRVEGVDWREGGECVTVGEDGRVNVVKIVNGEGLRYRKVFDGNGLVAYRAVKWASPTEFVTGGYGFGLQLWDQRKSGEAVSQLKGNWFQGKTSAIVHSIDIHPSRKHTCIAGGSSGTVFAWDLRWPQQPIVLSGVGASENINNPLSESEVWEVQYDSYTKSNVSSSRILPVMTCSEDGILGIIEQGEEPIELLAEPCAINSFDIDRQNPQDVICSLEWESIAVFSRP", "length": 361, "molWeight": 39354, "crc64": "CD98DF9A4866BD32", "md5": "CE7820B6B47DF493E8183DCAF81C2D12"}}
{"primaryAccession": "Q2HJF1", "text": "This is Large ribosomal subunit protein mL53 protein, from Bovine, contains 112 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q2HJF1", "organism_name": "Bovine", "protein_name": "Large ribosomal subunit protein mL53", "length": 112, "firstPublicDate": "2006-11-28", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mL53 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAALARLGLRSVKQVRVQFCPFEKNVESTRTFLQAVSSEKVRSTNLNCSVIADVRHDGSEPCVDVLFGDGHRLIMRGAHLTAQEMLSAFASHIQARGAAASGDKPSASTGR", "length": 112, "molWeight": 11998, "crc64": "9D3B654EBA365114", "md5": "E03C935C86C9FE62090960AB2D9D52E7"}}
{"primaryAccession": "Q2KIX7", "text": "This is Protein HP-25 homolog 1 protein, from Bovine, contains 212 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q2KIX7", "organism_name": "Bovine", "protein_name": "Protein HP-25 homolog 1", "length": 212, "firstPublicDate": "2010-11-02", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MPGGRRRVGSMNIAGFWILAQFVLLLVANVKSSADSELCGPRGARGPPGLSGLPGPPGYTGPIGMPGLTGRPGLPGLVEKCPPLPQSAFSVKLSGPFPGPSQPIVFQEVLYNHQGHFDPATGVFNCSVPGVYHFGFDIELFQSAVKVGLMRNGIQIRDKRAEAGDSHEQASGSSVLELEKGDRVWLESKLDREESEKGTTHAVFYGFLLNGN", "length": 212, "molWeight": 22556, "crc64": "7126AFF050793722", "md5": "B42A110D5EAF9B74283AB8649F38436E"}}
{"primaryAccession": "Q3E769", "text": "This is Uncharacterized protein YOL159C-A protein, from Baker's yeast, contains 90 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3E769", "organism_name": "Baker's yeast", "protein_name": "Uncharacterized protein YOL159C-A", "length": 90, "firstPublicDate": "2006-07-11", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQYCELDLSGQWLDTVYCEENFSDFVFIKFLNPSQFEEKIYCYTLHITKRTLENKRLLLYYEDEFKKHGHDINELVGDGIILRSCWNPRQ", "length": 90, "molWeight": 10933, "crc64": "07F9094A0DF54A0A", "md5": "2800E0203D771150C0CEA91D849EBB83"}}
{"primaryAccession": "Q3E823", "text": "This is Cytochrome c oxidase assembly factor 2 protein, from Baker's yeast, contains 68 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3E823", "organism_name": "Baker's yeast", "protein_name": "Cytochrome c oxidase assembly factor 2", "length": 68, "firstPublicDate": "2006-05-30", "FUNCTION": "Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane, Seems to be involved in the SHY1-mediated step of cytochrome c oxidase maturation, May aid in stabilizing an early COX1 intermediate containing the nuclear subunits COX5A and COX6", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the COA2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MRAVTRNKIVNNLYFSTFLIAFASVAIGSVLPCPAHSVDSDSPAVQQHKLQLAHEQELKRKDALSKKI", "length": 68, "molWeight": 7533, "crc64": "4ADDB91D3ABC012D", "md5": "F7E27564E1C38F9BC1C87D2ABECBD7EF"}}
{"primaryAccession": "Q3SZX9", "text": "This is Coiled-coil domain-containing protein 113 protein, from Bovine, contains 391 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q3SZX9", "organism_name": "Bovine", "protein_name": "Coiled-coil domain-containing protein 113", "length": 391, "firstPublicDate": "2007-03-06", "FUNCTION": "Component of centriolar satellites contributing to primary cilium formation", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTDDDSETSASETQAQEESDLPVFQLCGLVEELSYGNSALKTETEMFEKYYNKLELKDQRPPRLSEIKITGAEIAQLRSRRKSKSRMGMERVMGLSVDQKLELVQKELEDTKDEIRHMRANAERDLQHHEAIIEEAEIRWTEVQKEVHDFEKDILKTISKKKGSILATQKVMKYIEDMNRRRDNMKDKLRLKNVSLKVQRKKLLLQLRQKEEVGEALHDVDFQQLKIENAQFLETIEARNQELIQMKLASGNTLQILNAYKRSSLLKTSRVVILQSKLHHAMQMSLNLTKEFLLRKELLEKIEKETLQAEEDRAKALALNKQLRKQLSEFRAPQVMIYIWEKIRNGDLEKTIRMWERKVEIAEMSLKGYRKAWNKMKTTNEQLQAISGPGK", "length": 391, "molWeight": 45869, "crc64": "BB62FA52DB798334", "md5": "5412B178E0FFE2FD26706E7FC2599E74"}}
{"primaryAccession": "Q66S17", "text": "This is Natterin-3 protein, from Copper Joe toadfish, contains 364 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q66S17", "organism_name": "Copper Joe toadfish", "protein_name": "Natterin-3", "length": 364, "firstPublicDate": "2007-05-01", "FUNCTION": "Shows nociceptive, edema-inducing and kininogenase activity with release of kallidin from low molecular weight kininogen, The cleavage occurs at Met-Lys bonds", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the natterin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLSVLVVTLLAVSWTSAQPETFSIQTKEANMNPEPANIRVARSSSAQSNLQWNYWDGQGAVPDGAVSIWNGEEKRTDYVCSCGCSSGFYSTKTGANCHYAYGETEKTCSGFSILVNRDNFENLEWKGGSDGSVPKNAVEVCEKVYVGKNKYGLGKVHTKHEALFLPWHGEEHWYKDYEVLTVNDDVVKQELTQVNYKLDAAHPIKNPPETLRRSSASNSQCRPITKTVALEKAIQTEQSWDVTSTVTFGVESSITAGIPDIASATVSVSVETSLSVSLGSTTTKTTTHTVSVIVTVPPNHYCPVTMVATKYTADIPFTGKMTRTYRNGQKRTTSITGTYRAIQVGEIRADVQRCSEIAGAKPC", "length": 364, "molWeight": 39806, "crc64": "DC36A0DE0DE09022", "md5": "B4AACF81ACB0D2B91D9AFCEEAB3EAABE"}}
{"primaryAccession": "Q6C7L6", "text": "This is NADH-ubiquinone oxidoreductase assembly factor N7BML protein, from Yeast, contains 237 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6C7L6", "organism_name": "Yeast", "protein_name": "NADH-ubiquinone oxidoreductase assembly factor N7BML", "length": 237, "firstPublicDate": "2015-06-24", "FUNCTION": "Acts as an assembly factor of mitochondrial complex I", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the complex I NDUFA12 subunit family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MIPTPVLRFNPIADKVPKWKRIYHKWRGIQNMPFKSKYFVGYDLDGNSYWEFKNVNNPGRYRRIVEPAKPDLSLVDHKIPPQWVQWLRFTRPHHPTLEELIADKQRQELLQAKIAAYEAKWKEIPLKTAENADESRDMSLEDQLKPTFTEAELAEMAQVFEKVPQQAAPAPPRVPNMAAIEVEDIIKHYPENGPDTVLADGGRQRDHDLKMDYVEKERDDSGKPAEWTPKAAVRRRG", "length": 237, "molWeight": 27603, "crc64": "3CCA440C99A00B72", "md5": "4CDE282EF01B33C95728A1C2FFA4EBD8"}}
{"primaryAccession": "Q6K1L7", "text": "This is Probable RNA-binding protein EIF1AD protein, from Chicken, contains 188 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q6K1L7", "organism_name": "Chicken", "protein_name": "Probable RNA-binding protein EIF1AD", "length": 188, "firstPublicDate": "2008-01-15", "FUNCTION": "May play a role into cellular response to oxidative stress, May decrease cell proliferation (By similarity)", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the EIF1AD family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSRATKRKHVTREVLEEHVVPAPQQRIVRVLGSPGNNLHEVETADGSRFLASMPPRFRHHVWIKRGDFLLVDPIEEGAKVKAEMALVLLRPHVRFLQRQGLWPTAFAASPDRTPQESDGDSELFVNTNRATIETDTEEEEEDGGDTESSEEEEEDREEPLEDRPEDRPEDCADVGSAAQRRSTIETGT", "length": 188, "molWeight": 21235, "crc64": "02594DF74508F53B", "md5": "EC2C3084F3F95E6F87DE010576AF9552"}}
{"primaryAccession": "Q8GW20", "text": "This is Uncharacterized protein At5g03900, chloroplastic protein, from Mouse-ear cress, contains 523 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8GW20", "organism_name": "Mouse-ear cress", "protein_name": "Uncharacterized protein At5g03900, chloroplastic", "length": 523, "firstPublicDate": "2006-02-21", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MACVSTCLILSPRLTQVGLSSKKPFLIRLRSPVDRYSFPRMLTERCLSTRRKFNRHGIAVVKAASLDKVSGAIKPGGLVESDKLPTDVRKRAMDAVDECGRRVTVGDVASRGGLKVTEAQTALQAIAADTDGFLEVSDEGDVLYVFPRDYRTKLAAKSLRIQIEPFLEKAKGAVDYLARVSFGTALIASIVIVYTSIIALLSSKSEDDNRQRRRGRSYDSGFNFYINPVDLLWYWDPNYYNRRRAREDEGKGMNFIESVFSFVFGDGDPNQGIEEERWQMIGQYITSRGGVVAADELAPYLDVPSSKSAMNDESYILPVLLRFDGQPELDEEGNILYCFPSLQRTASGSSRRKEYVGKWFDWVADMEKFFKEKKWQFSKTSTSERALVIGLGAVNLFGVIVLNTLLNEMSVRPGGFLTFVKNIYPLLQIYAGSFFTIPLIRWFSIKRKNNQIENRNKARLQFARALESPDIALRRKLLSARDMAQKTVIGKDRIVYSTDRDMMEQNYETDEWDRRFKELEKSD", "length": 523, "molWeight": 59501, "crc64": "68160010F66D9AF3", "md5": "084901907E3B33D22552826F73D7C555"}}
{"primaryAccession": "Q8LFP1", "text": "This is PRA1 family protein H protein, from Mouse-ear cress, contains 241 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8LFP1", "organism_name": "Mouse-ear cress", "protein_name": "PRA1 family protein H", "length": 241, "firstPublicDate": "2008-10-14", "FUNCTION": "May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the PRA1 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MAFSPNPLSLSVPDPAFESWLRDSGYLELLDHRTSAAAAAASSSASVSSSAAATSAASDDVVSSITGGFFASLLSRLVTVSSLLTINPFSKLSADDFSGDTTPWTTGFIGNCDSYSFPSSSQQARMRVHENIKRFARNYATLFIVFFACALYQMPLALVGLLGSLALWELFKYCSDKWKFDRHPSMRKLSIGIGQCATAVLLTFLNVQMALFSALAISYSVMILHAGFRKLTPSKKPTRGR", "length": 241, "molWeight": 26069, "crc64": "C3B2EDF5D17A4BFD", "md5": "E6DE1455C5395232C257FFE509A69152"}}
{"primaryAccession": "Q8MMH0", "text": "This is Cysteine-rich venom protein 7 protein, from Parasitoid wasp, contains 109 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8MMH0", "organism_name": "Parasitoid wasp", "protein_name": "Cysteine-rich venom protein 7", "length": 109, "firstPublicDate": "2004-08-16", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSKVFVIILVALMVAISIASAHRPPPNPRCLPGHSKCKYEPKKNSCCLGFQCTERNQCELVYPGHHGKPCGKDNLLGCILPPPTFKPRPCGKYNLKGCKPIRPRPHPHH", "length": 109, "molWeight": 12101, "crc64": "E36701A8653B3AB3", "md5": "735CED72ED5EAFDA94CFD3C681E03C2C"}}
{"primaryAccession": "Q8NKC1", "text": "This is Probable catechol O-methyltransferase 2 protein, from Fission yeast, contains 281 amino acids, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8NKC1", "organism_name": "Fission yeast", "protein_name": "Probable catechol O-methyltransferase 2", "length": 281, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "SIMILARITY": "Belongs to the class I-like SAM-binding methyltransferase superfamily, Cation-dependent O-methyltransferase family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFAQALHWLTTSKLRYALALPFLFFILYTKTKKSKEQELENYIFSLPREKLDQIRGKPDEVINVIDEYVEQGHFLMNIGKLKGKIISEKIQQVKPKVMIELGGYVGYSAILFGKQLTDPSAHYYSLEVNPKFAKIASKIIDLAGLSNKVTIIVGKATDSLVELRRSLPNVIPSFEYLDFVFIDHWKDLYVPDLRVMETLDLIGQGSIIAADNILRPGVPEYVKYVQGSLDYRKEYDSTVSNVNGPQFIGKWNIIYKSKTIKVDDGKREKDAVEITEYIEAK", "length": 281, "molWeight": 32123, "crc64": "24022103FE9993B1", "md5": "E6B9263E16423A50E961BB4E213EE4A2"}}
{"primaryAccession": "Q8T0W3", "text": "This is Cysteine-rich venom protein 3 protein, from Parasitoid wasp, contains 63 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8T0W3", "organism_name": "Parasitoid wasp", "protein_name": "Cysteine-rich venom protein 3", "length": 63, "firstPublicDate": "2004-08-16", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRKPITLILVVALALVLLATSEVSAYRACGFPGRRCSPTEECCEGLVCQPRKNGPSMCYRPDP", "length": 63, "molWeight": 6869, "crc64": "5BBDD96CF024FEDF", "md5": "8408622729A03F3955361875455DBD67"}}
{"primaryAccession": "Q8T0W5", "text": "This is Cysteine-rich venom protein 1 protein, from Parasitoid wasp, contains 85 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8T0W5", "organism_name": "Parasitoid wasp", "protein_name": "Cysteine-rich venom protein 1", "length": 85, "firstPublicDate": "2004-08-16", "FUNCTION": "May be a phenoloxidase inhibitor that stabilizes or inhibits venom phenoloxidase while it is stored in the venom sac", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the serine protease inhibitor-like (TIL domain-containing) family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MCRYALIVLVVVVVATNLSEANIFDVPTCEPNRIYKTCGPACPPTCEDPDPDCNETPQCKAGCFCIPGLIENMKGGNCISPSLCP", "length": 85, "molWeight": 9066, "crc64": "45DF32C6001FD9F3", "md5": "E37F7DA9BA766E534DD34D3B55D0136F"}}
{"primaryAccession": "Q8W487", "text": "This is Uncharacterized protein At2g39795, mitochondrial protein, from Mouse-ear cress, contains 250 amino acids, is soluble, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8W487", "organism_name": "Mouse-ear cress", "protein_name": "Uncharacterized protein At2g39795, mitochondrial", "length": 250, "firstPublicDate": "2002-06-20", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the MAM33 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MALAWCVVRRSASKFASVYGGRVRSISAVANRASLARNPSSIRPFVSRALNYSTAIDRISSEQTLIRVIDSEINSALQSDNIDSDEEMTPGSFPFRIEDKPGNQNVTLTRDYNGEHIKVVVSMPSLVSDENDDDDDDDEGPSNESSIPLVVTVTKKSGLTLEFSCMAFPDEIAIDALSVKHPGDSLEDQLANEGPDFEDLDENLKKTFYKFLEIRGVKASTTNFLHEYMTRKVNREYFLWLKNVKEFMEQ", "length": 250, "molWeight": 28061, "crc64": "EB8884B390FE7D47", "md5": "7705398325C4A83DE8C569D1F26A7364"}}
{"primaryAccession": "Q8W4F1", "text": "This is Probable plastid-lipid-associated protein 10, chloroplastic protein, from Mouse-ear cress, contains 284 amino acids, is soluble, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q8W4F1", "organism_name": "Mouse-ear cress", "protein_name": "Probable plastid-lipid-associated protein 10, chloroplastic", "length": 284, "firstPublicDate": "2007-05-15", "SUBCELLULAR LOCATION": "Plastid", "SIMILARITY": "Belongs to the PAP/fibrillin family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDRIASATFSCPAISLSRVCRISPFGLNIKTNHRKRFSCRVAVASGETSARVVVDNELDLEHKKHDLLRAVQDTQRGLTATSDQRSIIEEALVTVEGFNGGEEIDPVKLDGTWRLQYTSAPDVVVLFEAASRLPFFQVGQVFQKFECRDRSDGGIIRNVVQWSLPSLLEEQEGATLVVTAKFDKVSSRNIYLQFEEISVRNININEQLQALIAPAILPRSFLSLQLLQFIRTFKAQIPVNATSPGRRSVGGLYYLSYLDNNMLLGRSVGGGGVFVFTKSQPLEL", "length": 284, "molWeight": 31580, "crc64": "7822EE32645E115C", "md5": "DCBA98A0375A1C9F656D05135B48A14C"}}
{"primaryAccession": "Q91XT6", "text": "This is Tandem C2 domains nuclear protein protein, from Mouse, contains 489 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q91XT6", "organism_name": "Mouse", "protein_name": "Tandem C2 domains nuclear protein", "length": 489, "firstPublicDate": "2003-07-25", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAAEFIKSCCRGCLYGETEKQKFSVDRDFKASASSSQNTIGIPPLTSVLVKPQVGCNEDYLLSKLPCDGKEVQFVVPRFKLSYIQPRTQGIPSHLDELEGSARASFGDQKTELCSSFYHGPSYDVYNPCYMYQHFSPDLSRRFLPHCETKQLYGSVCDLRTSKLPGSSGLSKSMLDLTTSSQRFIQRHDSFSSVPSSSSSRKNSQGSNRSLDTITLSGDERDLGRLNVKLFYNSSAEQIWITVLQCRDISWPSSYGDTPTISIKGILTLSKPVHFKSSAKEGSNAIEFMETFVFAIKLQNLQAVRLAFKIQTQTPKKKTIGECSLSLRTLSTQEMEYSLEIIAPSKISVCQAELELGTCFQAVNSRIQLQILEAQYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASSGRVKWGETMIFPLIQTEKEIVFLIKLYSRSSVRRKHFVGQLWISEDSNNIEAVNQWKETITNPEKVVIKWHKLNPS", "length": 489, "molWeight": 54988, "crc64": "CFBB3E069EB68D5A", "md5": "5263715AA7FB22CD380EC9950A8F48F9"}}
{"primaryAccession": "Q944H2", "text": "This is Protein ABCI12, chloroplastic protein, from Mouse-ear cress, contains 391 amino acids, is membrane-bound, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q944H2", "organism_name": "Mouse-ear cress", "protein_name": "Protein ABCI12, chloroplastic", "length": 391, "firstPublicDate": "2009-07-07", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MNHSNLANPTVSLTVTLIPKHPIRHLTSPIPNRNFTNPKLLFPLRLNETPSSSLAAKRVFIVRATVDGDGKTGNWVNRLPIPGLGAENVFRLISSATGSPIGQFISSPVTFLHSVDPRIKLVWLLTLVVLPARANLVVRLGLVLCTALLSILVLPRQVWIDQLARVSLLSGILFITLGLGSDGAPPMLQSRTPPSSITSLPNLPMSLSGYSYMLLKLGPLQFTRKGLSVGSTAACLTFIIFQSASICLATTTPEQLALALRWFLFPLTYIGVPVSEIILTLLLSLRFINLVFDEVRSVSLGIVSRRVNWQQLTVLETLDIFASFIRRIFKNIFRHAEQISQAMIVRGFRGESSSHKIYFFSGSSNKFADFASVLCLIGVISTALLSEYFLV", "length": 391, "molWeight": 42938, "crc64": "6FD5ED106D0AD339", "md5": "376DF47C214E182976438D8DE3699CD9"}}
{"primaryAccession": "Q94CC0", "text": "This is Uncharacterized protein At5g49945 protein, from Mouse-ear cress, contains 480 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q94CC0", "organism_name": "Mouse-ear cress", "protein_name": "Uncharacterized protein At5g49945", "length": 480, "firstPublicDate": "2006-07-25", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MSRYFSFFFLALFLHYRIIVASPFEGFDAEEDDVTDDSSHLLHHSLPPPLLTQSHSSLSDPDPEPEPSSAECKSDLITESDLEHQSDSKTPSSTPFEYWDEDEFEGLPVEIETLESPLITENGTHADPKTPDLKTSSEAQGDTNDQTKKKKSYAVEIACVCFLIALAINYFVGKRENESLALAWAAKFASKDTIFQKNFSMLGVSELEDSPLLLKEALNVFKFYASGRRYCHGLLATMELKSRHDLISRVFNLVVPCKDEITFEVYMNEETMDHVVFAMTKKKAAKTMQKEMRDLQRFAGIVSPPAGRKWVSEEFALISESKEVAADLITDTVLDQVFGDKAVDKYGKNFMSMHISDQHPGKHKKMMLFKFSLPDAKHMDDIVRLVALIPYYIDLVGRYRLSSQARNKTESGRQKAAEEAYKELHNARQEALQKKKAEKKKMMEEAEAKMSAEVIRKKEAKERARQVKKAVPKMKMSRSH", "length": 480, "molWeight": 54592, "crc64": "27B2AB130F653443", "md5": "E9C904533FDF5A03EE2324741C79CC10"}}
{"primaryAccession": "Q99N93", "text": "This is Large ribosomal subunit protein uL16m protein, from Mouse, contains 251 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q99N93", "organism_name": "Mouse", "protein_name": "Large ribosomal subunit protein uL16m", "length": 251, "firstPublicDate": "2006-06-13", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the universal ribosomal protein uL16 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MWRLLTRVPAPLLRMHFSDSWAALPTSAGLKTLLPVPTFENVSIPERSKLKFVERVPLVPKVRREPKNLKDIRGPSTEATDFTEGNFAILALGGGYLHWGHFEMMRLTINRFMDPKNMFAIWRVPAPFKPITRKGVGQRMGGGKGAIDHYVTPVKTGCLVVEMGGRCEFEEVKGILNQVAHKLPFPAKAVSRKTLERMHQNQRERELNNQNPWTFEHIATANMFGIRKFLSPYDLTQKGRYWGKFYMPKRV", "length": 251, "molWeight": 28804, "crc64": "8753B4DBBCC63ABB", "md5": "EE0354B4A9707EE08FEAC90565F5F1D2"}}
{"primaryAccession": "Q9C0Z8", "text": "This is Uncharacterized protein PB1E7.11c protein, from Fission yeast, contains 319 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C0Z8", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein PB1E7.11c", "length": 319, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MTAVPKFYRAALSDKYKRIVLDAMSRGYRPSEGIWFRVRTYFPVSYPADIKSEALPSRYFQLKAFPYYNAEERLKEWIVLAKVRPEIPLPPAAPIPMKKASNTEPVEKEISSFFSEEGATKENEDFINEKEEEEDLSFSINAAHTFSNIGTWYLARANEVAEFKHQQKKIVAINKGRFPKSLLLQYVPSNISSERLFKTLKRHGLVQGVMEMNTKPLKTSKTTPTKKMLSTTDTKDWLVITPVPNKLTRLLHKSQWDLIEKLSFPLRLSDYKKITKKENIGLSSRDEMGDPLLFAHSYFELTPENKTSAPKINVKSEGK", "length": 319, "molWeight": 36702, "crc64": "8E730853F35C51B0", "md5": "144D124D6DDADE6FE28717C8B4812967"}}
{"primaryAccession": "Q9C1W6", "text": "This is Uncharacterized protein C713.09 protein, from Fission yeast, contains 395 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9C1W6", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C713.09", "length": 395, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSDREEKLAAAKQRLLEVKKKKRQAKSKNSVAEDNVDRESNDGNNQVNEPTGNDNTQVVENTEDISASNVVSAEGAEASTGDASTQSPETSENVVKNSVDESVAEKPEKEDLAVIESEDKAAKPDGEIKKNVETEVTSRSTSSQEKDELEKQVKTLHDLNEQKDKKIKELKERINDLTYDYETLKANADDSEGKQTLVSKREAALEEFQSKLLIRENEINKRELKMNGKEDDLKKREKDLENRLLKVEEHEKSLNERATKLSEANENFNNRFKEFEEREKSAIKQNKEQSSEGSKTANQTHEQKELINSLEKKVSDIALEKQLLEEAVERYKLAMVEFAECQRRLKELEAMHFEQPGSVTEKLFPDPTNFEVIDNVSIDLTLTGFPGAHGIPFSV", "length": 395, "molWeight": 44770, "crc64": "604AC5E5129E8835", "md5": "F0D559934AE84F88EF2AA8847209633D"}}
{"primaryAccession": "Q9D6I7", "text": "This is Divergent protein kinase domain 1A protein, from Mouse, contains 428 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9D6I7", "organism_name": "Mouse", "protein_name": "Divergent protein kinase domain 1A", "length": 428, "firstPublicDate": "2007-04-03", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the DIPK family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MARSLCAGAWLRKPHYLQARLSYMRVKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPACNSLCVTETLYFGKCLSNKPSNQMYLGVWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDRDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVMELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNEKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDLSTMKCTSEVIQPNLAKACQLLKDYLLHGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS", "length": 428, "molWeight": 48936, "crc64": "7111D7C81F082822", "md5": "62E73E58D03CD818C7C0F78D983ADF07"}}
{"primaryAccession": "Q9FFA2", "text": "This is DUF724 domain-containing protein 9 protein, from Mouse-ear cress, contains 426 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FFA2", "organism_name": "Mouse-ear cress", "protein_name": "DUF724 domain-containing protein 9", "length": 426, "firstPublicDate": "2016-06-08", "FUNCTION": "May be involved in the polar growth of plant cells via transportation of RNAs", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFSPGTTVEVSSKINNKEVVWVPAVVIKEFKEDDEYKYIVRVYDKSFSCKGNKAARLNKTVDLCSLRPTPPSISVEEYQLKEYVEVFHDGMGWRQGRVMKIQERVMLSQGRVMVSQGRVMGNLSQKCYIVLLEATKKQISFKQSDLRPLQVWEDGVWKMLQTRESSLTQGSGDETSDSVRNANESDPPVTPRPGITTPPLKQIEAETQRKTLPRNQNASVNDSTRENENSEDINRKRKREESLCSDASVEDTTMTLPFEKKLSIWKTLESVETVPQSPHFSPLVETREDCREMSAVGMMLTFPCLLEEVKSLQHDNSISSLISLSNNFCELEKHGFNVKAPQSRISKLLSLRGKQSMKMDELKGAEKVTAEKESIKIENERKILELQRLNEEVDKEIAQSKSCAAKIVQQLEDVELQFQTTASAPW", "length": 426, "molWeight": 48445, "crc64": "5F0D023451B23BC1", "md5": "57B7274CD2A9CDCBCC866E55F5E8CBF3"}}
{"primaryAccession": "Q9FRK5", "text": "This is Uncharacterized membrane protein At1g75140 protein, from Mouse-ear cress, contains 617 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9FRK5", "organism_name": "Mouse-ear cress", "protein_name": "Uncharacterized membrane protein At1g75140", "length": 617, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MADSQNGKSAFFFFFVSLILLFLSPSYSDVTASESDPIPYENSDASPGVVTSSESDRQGVSLHRLEELVRNLTELVARLDAKLSETPFKVKKEITRDEIEEKAKAFSVTKYSPFWSERFEFTSAVKLDSEATCINVLPFRDHEGLSKYFAVGDSSGRVFVFLRNGDVLVEFFTTCDSPITAMVSYMSVYKNESFVVTGHQSGVILLHRLREGSIGEDLNSAVMENVGKFDGTEDGLQVTLLEVHHVGRVRYILATDLSGKLTVFTENRTVYGSVSPTSRPLVFLKQRLLFLTETGAGSLDLRSMKIRESECEGLNHSLARSYVFDASERAKAYGFTSEGEIIHVLLLGDIMNFKCRVRSKKKVQMEEPVALQAIKGYLLIVNQEKVFVYNVSTQHYVRTTGPRLLFPAALEDIRSTFLSHRESTKTTDHQKLEKVTPLIASDREKLLVMGLGDGYVATYKSKLPISKAEFNTMLWSSPVFFFILFLFGAWHFFSKKKESLTAWGPDDPFSSTTMSSSSTTTAQNSSAFSESTRRNDDHMDLRRRYVSPSRYPPGAATGAYRSVGSNDPSSRAPVETTNYRTTAQEMKYRGGSGLDSGGFGKRRESLFGNNKALDDES", "length": 617, "molWeight": 68909, "crc64": "CE259912CAAD7B78", "md5": "30DC6A0F15EF171ED2BD36102AF36C8E"}}
{"primaryAccession": "Q9HDZ5", "text": "This is CRAL-TRIO domain-containing protein C589.09, mitochondrial protein, from Fission yeast, contains 388 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9HDZ5", "organism_name": "Fission yeast", "protein_name": "CRAL-TRIO domain-containing protein C589.09, mitochondrial", "length": 388, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFSRLWVRCRCSTALSAAAAGTFFFRRSQKQPEPETVDEKVSFESYSPLKLMIQKTWPRFQEHKEYRESFIRLAKCDSPDAILVRFLASCNNDSHEASQKLINTLQWRVDTGVERIVERGELYAKETNDDQFLEQLRTGKVTMLGRDLSDRPICYIQVHLHQPSKLTQNSLREMTVWVMETMRLFLRPQKTLKDSMDSPQNVNVLFDLSNFSLHNMDYSFVKYLASCLEYYYPQSLGVCILHKSPWIFRSVWNIIKGWIKPEIAAKIVFTQSANDLEKYIDYSVIPTSLGGGNKKIFQYIEPVEHENDAVIEDSAEKTAALARYYAYFSEWEQHSLNWAKLDDDDAQNEKVRLCCDAAGTNFANCYWNVDKYIRARTVYDRLKWIGNV", "length": 388, "molWeight": 45305, "crc64": "55EC1246AD1682BF", "md5": "2D95AF0DB17A991D9AE6C9F59CCD12CD"}}
{"primaryAccession": "Q9LK31", "text": "This is Kelch repeat-containing protein At3g27220 protein, from Mouse-ear cress, contains 426 amino acids, is membrane-bound, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LK31", "organism_name": "Mouse-ear cress", "protein_name": "Kelch repeat-containing protein At3g27220", "length": 426, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MANKPDHHHHHHQSSRRLMLVLYFTSVLGIGFIAAFLCLSSSIPSVSAVFSIWVPVNRPEIQIPIIDSKIVQKRSKQSNDTKDHVRFLSAIFADIPAPELKWEEMESAPVPRLDGYSVQINNLLYVFSGYGSLDYVHSHVDVFNFTDNKWCDRFHTPKEMANSHLGIVTDGRYVYVVSGQLGPQCRGPTSRSFVLDSFTKTWLEFPSLPAPRYAPATQIWRGRLHVMGGSKENRNAVAFDHWSIAVKDGKALDEWREEVPIPRGGPHRACVVANDKLLVIGGQEGDFMAKPNSPIFKCSRRREIFNGEVYMMDEEMKWKMLPPMPKNNSHIESAWIIVNNSIVIVGGTTDWHPVTKRLVLVGEIFRFQLDTLTWSVIGRLPYRVKTAMAGFWNGYLYFTSGQRDRGPDNPQPGKVIGEMWRTKLKF", "length": 426, "molWeight": 48496, "crc64": "EAF7A4910790FE5B", "md5": "AB9B9D56462DD2F366011A63A51A7500"}}
{"primaryAccession": "Q9LP21", "text": "This is Putative pumilio homolog 10 protein, from Mouse-ear cress, contains 528 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LP21", "organism_name": "Mouse-ear cress", "protein_name": "Putative pumilio homolog 10", "length": 528, "firstPublicDate": "2010-11-30", "FUNCTION": "Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MEIFNFGQASDHRRLPDFGSGGFLQSLDTNPFLKNQYYNNSVEALELCKKLNKMGISCDMSIWTKPEEPFRVDPGDFGAKTLHESFGFDQNLTGASQIHDGFRNFSSVRVQNNNFHGVSPSPGLLGLQDSFNPNGFEEMMAFKDHKDFLLDHINEPIKRSPFLRGNDAFKGSLMFEGIRVSQILAAMEGSGASYPDEPKINGGLPLDLVSMVEIYGSVNLMARDQIGCRALQKLVEEGTVLDSKVIFLEIIDHVVELSMDPLGNYIVQKLLVVSDEEQRTMIVSVLTSKPRELIKICLNTNGTRVIQKMIKTVKTKQQIALVKSALEPGFLVLVNDSNGYHVLQSCLEFLVPNDNKFVVEAATEYCAQLATHQYGCYVLQCSLINTVGLQHERLVAEISRDSLRLSQDPFGNYVVQCLIDQQVSSVNLLLPFRTHCIELATQKFSSHVIEKCLRKYPESRAEIVRELLSYPNFEQLLQDPYANYVIQTALSVTKGAVRARLVEKVKRFGKLQSNPYCKKIFSKTILKK", "length": 528, "molWeight": 59381, "crc64": "7FBBC3A654FF7CC1", "md5": "4F81CB05CEEE16E05CEBBE3102110A26"}}
{"primaryAccession": "Q9LVV5", "text": "This is Thylakoid lumenal 15.0 kDa protein 2, chloroplastic protein, from Mouse-ear cress, contains 223 amino acids, locates in Plastid.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9LVV5", "organism_name": "Mouse-ear cress", "protein_name": "Thylakoid lumenal 15.0 kDa protein 2, chloroplastic", "length": 223, "firstPublicDate": "2007-05-29", "SUBCELLULAR LOCATION": "Plastid", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAMLFRPPPSQCRSFSPFVFNYSSREVSSSSRLSLKTSGDEENWVSRFRSKSLSLVFSGALALGLSLSGVGFADAKVGVNKPELLPKEFTSVIDVADFLSNGQEKRIAQEIANLEKDTGFKLRVLAQNYPVTPGLAIKDFWQVDDSTIVFVADPTFGNILNFNVGATVDLDIPRSFWSRLAGKYGNMFYWKEKGEDASIEAAVMAISSCLREPVGRNNCAEIQ", "length": 223, "molWeight": 24569, "crc64": "BBD922039FA5CA28", "md5": "DD4F6C6EF7A5FBF2EF6B5A6F7B2E2FC4"}}
{"primaryAccession": "Q9M427", "text": "This is Oligouridylate-binding protein 1 protein, from Leadwort-leaved tobacco, contains 406 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M427", "organism_name": "Leadwort-leaved tobacco", "protein_name": "Oligouridylate-binding protein 1", "length": 406, "firstPublicDate": "2014-02-19", "FUNCTION": "Heterogeneous nuclear ribonucleoprotein (hnRNP)-like protein that acts as a component of the pre-mRNA processing machinery, Functions to facilitate the nuclear maturation of plant pre-mRNAs, Binds with high affinity to RNA molecules that contain AU-rich regions, May bind to the 3'-UTR and protects the mRNA against exonucleolytic degradation, Associates with nuclear poly(A)+ RNA in nucleus in vivo, Does not stimulate transcription or the 3' end cleavage/polyadenylation reaction", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMQQQRLKQQQQQALMQQSLYHPGLLAPPQIEPILSGNLPPGFDSSTCRSVYVGNIHPQVTEPLLQEVFASTGPLEGCKLIRKDKSSYGFVDYFDRRSAALAIVTLNGRHLFGQPIKVNWAYASAQREDTSNHYNIFVGDLSPEVTDATLFACFSVYTSCSDARVMWDQKTGRSRGFGFVSFRNQQEAQSAINDLNGKWLGSRQIRCNWAAKGAGAVGEQNSDAKSVVELTSGTSDDGQEKVVNEDAPENNPQYTTVYVGNLAPEVTSVDLHRHFHALGAGVIEDVRIQRDKGFGFVRYSSHAEAARAIQLGNARLLFGKPVKCSWGSKPTPPGSSSNPLPPPAIGQIPGLSAMDLAAYQRQLALAKMAGAQAFMQPQGQRIGAPGQGIYDGGYGGIASTQPPMYF", "length": 406, "molWeight": 44088, "crc64": "7E73C4C766112600", "md5": "EF0BC9CDDC40100C675EE61DEAC23582"}}
{"primaryAccession": "Q9M815", "text": "This is Protein PLANT CADMIUM RESISTANCE 8 protein, from Mouse-ear cress, contains 190 amino acids, is membrane-bound, locates in Cell membrane.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9M815", "organism_name": "Mouse-ear cress", "protein_name": "Protein PLANT CADMIUM RESISTANCE 8", "length": 190, "firstPublicDate": "2011-05-03", "FUNCTION": "May be involved in heavy metals transport", "SUBCELLULAR LOCATION": "Cell membrane", "SIMILARITY": "Belongs to the cornifelin family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGRVTTPSEEDSNNGLPVQQPGTPNQRTRVPVSQFAPPNYQQANVNLSVGRPWSTGLFDCQADQANAVLTTIVPCVTFGQIAEVMDEGEMTCPLGTFMYLLMMPALCSHWVMGSKYREKMRRKFNLVEAPYSDCASHVLCPCCSLCQEYRELKIRNLDPSLGWNGILAQGQGQYEREAPSFAPTNQYMSK", "length": 190, "molWeight": 21179, "crc64": "9708EF167B0031C0", "md5": "8C3FEF842BB348EC86CA870AE17834CC"}}
{"primaryAccession": "Q9P3A9", "text": "This is Uncharacterized protein C1565.05 protein, from Fission yeast, contains 773 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P3A9", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C1565.05", "length": 773, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MASFGELSFLSEISNIHKSNKKHEIQSAGTVALDNGVESPYYICVQVENQGIEVYHMKDERLFASCPLPEKTRFSCSPIYIKEGNWHYIWTCTSLKSNGEWKILLWKFNDLEEESEVVYRDISNQQIFALHFISSTGQLVIVFRNGKIAFLDPEDDKVHMSASVNESATLLQSMYVPSQANPIDAVRLASNEASGTNNNPKEIEMNSDTTSSVPKSGSTSFSANVTSSTSMVYLLYSVHVDKIIQYYVDSFSVSERRLVNTRAVVLKEVQAPSHILMSKDSTSIYTISLEGLSIYSLHDESKSYMLIKILHFQSISKIEHIELISDNFLLIQHDSQLSLWDITFGTIQDVYDLKQKPTILTFTCYKSSLKKMNQNSQLTGYIAVLLKKGLAIVPYTLPIKMLLADAVGKRTSKIGKLRGTNELIGEGVLTKSKNGPSMRDQLLKNIQLQDHSLRDELISLRSLAEQKNTIEFDAKFLGVVERYQNQYANNCKILKTSSVLPIPFAHAIESLLFSLDEENELQVSCAASGTLNYLIRHRLFSYSTLVQKGFSGSVFDCLYKFQKDIAFNFLERTSDISAYEIACAIKTAINSSKVKLLRSALARLSLFDSTTSREALLLAFVPEDFDSLFKTLGNLVVDSNLASVKFNLETYIYCLSVVLDAMGVGGVASSSENLEAARILYNDLQEKLTNLTAMSLVLPAISEIVKRKKDVHAERVQFYANPQPKAIVDDMGDLATLLKKDFLSEKRKGKSQRARGKEIDMAIGKYTVERLEI", "length": 773, "molWeight": 86680, "crc64": "E3A3F646547B58F0", "md5": "9CFEB2A817348895DBA7FB2C55B18FC3"}}
{"primaryAccession": "Q9P3B1", "text": "This is Putative Rho GTPase-activating protein C1565.02c protein, from Fission yeast, contains 374 amino acids, locates in Golgi apparatus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P3B1", "organism_name": "Fission yeast", "protein_name": "Putative Rho GTPase-activating protein C1565.02c", "length": 374, "firstPublicDate": "2008-01-15", "SUBCELLULAR LOCATION": "Golgi apparatus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MEHDLERLCFIGGYDNDNDKVIVVVTKNLELFKKYDDINLIKEAYNHVHKLIQKDERYTAVFFAHDSTVFSYLGLSLKAYYGMDYYLHKNVKAVYVIHTDWMSKVAIRTLLSIASPKFTRKFRYLNSISDLNKYIPLSHLKLPPIVYEFDRNVEPAIFPSNPSATSNFIFPVQQWTRPPDALVEGMQVVSKSLQTEGLFRKSCSRKHLDIVIELYDNGCMVDLEAFGPIAACSLIKHLFRSLPSPLFSAEFLNGLTDHMDSGIDYAVSLQKLIDASMDKNSQKLARLIFSLLYQITQHEQENMMNAQNLALCIGPSFSKADNIAELMSMKDKEYNPYCYFLEYAILHWNTLFANEENWDSYIPQDPTLLLPKTP", "length": 374, "molWeight": 43109, "crc64": "F21DBA690457E2F5", "md5": "E67595A273332AAD4BCA67EE0C0F2844"}}
{"primaryAccession": "Q9P3U8", "text": "This is Uncharacterized RING finger protein C548.05c protein, from Fission yeast, contains 468 amino acids, has 1 RING-type Zinc finger, locates in Nucleus.", "functionDomainRange": [{"location": [85, 123], "description": "RING-type", "keyword_description": "Zinc finger", "textural_description": "RING-type Zinc finger"}], "meta_data": {"primaryAccession": "Q9P3U8", "organism_name": "Fission yeast", "protein_name": "Uncharacterized RING finger protein C548.05c", "length": 468, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {"RING-type Zinc finger": 1}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVKRSSHRQVVLDEDDEENYNNNLDDEKMEVLLIPQSNSTTFASSDATQMYKKSRISSNSENKKQIPDTKTLLETFQKIKKTLECPICTEALQRPFTTHCGHTYCYECLLNWLKESKSCPTCRQKLYTQPSPAYLVYEIMNVVAASNSGFPLVGINENPAKKQKEVLFDGMFKQEDSHYPRSILVDSEDGVLRCARCQWELENPYHCDHCGFQISDDQDSGREWFWDGENAESDSSLNGDNTRGGNISTNRAFNNMGHAPITAVPQDWLRFDEGEEFVGSDLESDFSGPGEYDVDDGFIDNRATSQLSPVESDDDFVAPVNGSNGNGITALDSTDSEEIDIMNGFDEERDSGGTNMVSRSETCYNDGQRYDELRRELADIQNESLDSLNSSSNNSPSHNNIHSRQHPFSSDEDEGNIVTNGTGLRSSQSSSQNRGFDLEPYSEVFTASYPRRQARRTRTIQLDSDEES", "length": 468, "molWeight": 52715, "crc64": "30163BB97E6E50E5", "md5": "5A29242CFB1AB30033FA94687A42955B"}}
{"primaryAccession": "Q9P4E6", "text": "This is Lipase 9 protein, from Yeast, contains 453 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P4E6", "organism_name": "Yeast", "protein_name": "Lipase 9", "length": 453, "firstPublicDate": "2003-11-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MLYLILFLIAPIYAGVLLPTKPSIDPFYNAPEGFKNATVGDILQFRKTPKSITGGFVPLNVQNSWQFLVRSEDSFGNPNVIVTTVIEPVNADPSKIASYQVSENAARADCAPSYALQFGSDVSTLATQAETYLLAPLLDKGYYVVSPDYEGPKSTFTVGKQSGQAVLNSIRASLKSGKITNIAEDAKVLMWGYSGGSLASGWAAALQPDYAPELSRNLLGVALGGFITNVTATVEATDDTIFAGIAANVLGGIANEYPEFKSILQNDTNKSSIFNKINNHCLTDSFIKYVGARFLTGDNKVFKSGWNIFKNLVVSKIVKDNGLVYQKQLIPTIPVFIYHGSMDQISPILNPKKTYQNWCDAGISSIEFAEDLTNGHFTESIVGAPAALTWIIDRFSNKPPVDGCQHVVRTTNYEYPNVSSSILDYFKAAMDVVAQQGLGPNIQKDQLEIKSNL", "length": 453, "molWeight": 49232, "crc64": "6F96E2D0323F7FEE", "md5": "38E79B67161C2FA1DCBD1873678F0D54"}}
{"primaryAccession": "Q9P4E7", "text": "This is Lipase 7 protein, from Yeast, contains 426 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P4E7", "organism_name": "Yeast", "protein_name": "Lipase 7", "length": 426, "firstPublicDate": "2003-11-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MFVFLALITLTTCLQIPLNPTIDDFYNPPKDLETSQLGDVLKWRKMPFPVTSMFVNLPISNAWQISVRSQDTLNNSLAIVATILEPPNGDKNKLISHQAFENSPLLSCSPSYSMQVPSFETFQIQADLIFISGLLSQGWYVVVPDYEGPNSVFPVGRQSAYSVLDSIRGTIKFFNSTGNSTVKTALLGYSYGAVASLWASIVQPNYAPELELVGAAVGCTIPNITAFIEKVDEGPYSGLIVNIFNGLANEYRHFRDRLIHFGALQPLGCLFPICRKFFFQKMIGGVYDAQVLTDETIKETIEINNLLSTRAVPQIPVFLFHSKFNEMSPFLEILKLEKLWCSQLGVNLEIAEDMSYNHMVEAFSGMPAAITWIEKRWNNSTLGGCKHVHRLSNFEYPGIAPFLSQYFRSSLQMVLNNNRYFNNTTR", "length": 426, "molWeight": 47854, "crc64": "2DBBABC4CBCC6A85", "md5": "FAB9164D2D2437ABDD8CF1A3F5457B7E"}}
{"primaryAccession": "Q9P7F4", "text": "This is Zinc-type alcohol dehydrogenase-like protein C2E1P3.01 protein, from Fission yeast, contains 348 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7F4", "organism_name": "Fission yeast", "protein_name": "Zinc-type alcohol dehydrogenase-like protein C2E1P3.01", "length": 348, "firstPublicDate": "2008-06-10", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKAVIADGQNGVEVISDAPKPTPEKGEFLGRVIRVAFNPIDWKTLYNASIEKGTVGGTDFVAVVEDVGEGVDRSKYIGATVSGWAPGPLDGSNAAWREYITLDVNLVYFVPKNITPSQAATLPLTFTTASQGLNQYLGLPLPPTDGSKNSAQQKWVLVWSGSSSVGQYVVQLAHHAGYKVIATCSPHNFDWIKKLGADFTVDYHDPNVVEIIKKATDDSVFYGFDAASFPETSTLAVKAFSSKVKDGKLINILSSPPSPRSEVKIIGIIDYSLFNREFNFFGNKIEPIQASYDHAVEVYKKLTGWLQEGVIIPNRVKEFDGGLQAIPKALREFASGKHSAVKFVVRID", "length": 348, "molWeight": 37929, "crc64": "63E638A712AFF1C2", "md5": "7579DA6BC4B3C84DF173B62F0F9B2608"}}
{"primaryAccession": "Q9P7M0", "text": "This is ABC1 family protein C21C3.03, mitochondrial protein, from Fission yeast, contains 692 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7M0", "organism_name": "Fission yeast", "protein_name": "ABC1 family protein C21C3.03, mitochondrial", "length": 692, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the protein kinase superfamily, ADCK protein kinase family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MISFSHWNSHIRSGLSLSMIPSANSRFAFIIQRNYIPVVNSQNTRWKRLCGTQSVWSPYKKKHVLVNRLKHISLFPKPIFARKFTTRQKSEDQKQWRILRITFLVLPFTVGGLWILYRVKNRKNNIFSFDELELEERSNRPRSIFGKIKQFFNILLRSFNLFIIFSPIIITLPFIALISFLHLRSLSSLTVSIWLRFLVTQLERAGATFIKLGQWAASRTDLFPPAFCKTLSKLHSHVTPHSLAYTQSVICKTYKVESIEEIFVNFNPIPIGVGAIAQVYTATIKKAATQQDNSYFTSMLQSIGFRQKNISDAPVTQDVAIKVLHPNVEKYISLDLQILGFFAKLINLVPSMKWLSLPDEVKVFGAMLNQQLNLHYEALHLNQFRLNFRGNRYVEFPAPYDDYTTNQILLEDYMPGIPLSAFLKHKSGPFNKLLANTGNNALFQMLIVDNFTHADLHPGNVLVKFYKGIPKTIFNQDNEINDSIYKILSTCSTEEWDSAMEELNILGYRPTLVFLDAGLVTKLSTQDQKNFLDLFQAVLTFHGYEAGLLMVERSRQTERVINKDIFALKMEHLLNEIQKSTLSLKSLQIGTILQEVMTMAREHHVRIEANFANTVLSILLVEGAGRQLYPEMDLLSNATPYLRSASSKSNVSLTNPMVQLWIALEARQFLLLSTSKETVEKWVKSDMIAPNI", "length": 692, "molWeight": 79369, "crc64": "326AAA72B41E9085", "md5": "B3701C9E114D62FC413E88147C50E180"}}
{"primaryAccession": "Q9P7N6", "text": "This is TPR repeat-containing protein P27G11.02 protein, from Fission yeast, contains 356 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7N6", "organism_name": "Fission yeast", "protein_name": "TPR repeat-containing protein P27G11.02", "length": 356, "firstPublicDate": "2009-02-10", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MRMQWIWKSRRSLQNVFIRRSSQYHKPFWRRPLPATLLGCAVLGVAAVYFAKPSPIDENYPRSVAKYLHEALYRQKGENNHDFQDAWKAYQSAIKQAESEKMDMESPPVQGIRLQMANLLASAGALHKAWSMYWDILERTSKLPDFLEQRVLIASKLIELSEPLGLQKDATKAADLIVKALLSKQFNGDDEQKSRLFEQSATLYFQAGTPSYAVPLYHEALNLTMANPSCHGLILMNNLATSLLAQTETVDKKHHETLMKQSQSWSQKAVDSYYFAYPKDRNQECHAGCAAAFYTLGQIAERQGNIDLALKHYKNSEALRKDDPYNDGSMLSHIAIDRLDKDAFIKKLDKSSSPTD", "length": 356, "molWeight": 40508, "crc64": "CCE58D959AF92778", "md5": "B678662B8E19E352000747D0D2987AE1"}}
{"primaryAccession": "Q9P8W2", "text": "This is Lipase 3 protein, from Yeast, contains 471 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P8W2", "organism_name": "Yeast", "protein_name": "Lipase 3", "length": 471, "firstPublicDate": "2003-11-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKTLVVLCTLLSIIFASPLSLKSPLVDDFYNPPRGYESAKLGEILKLRKTPGKISSLFIPVEVKNSWQLLVRSEDSFGNAAAIVTTVIEPFNADPSKVVSYQSWEDAANIECSPSYGMQFGAPLSSVQTQVDMIFIVPLLDKGCFVVLPDYEGPKSTFGVGRQSGKATLDSIKAVLKTKDFSGINDDAQVAMWGYSGGTIAAGWAATLQPKYAQELKKNLIGAALGGFVINITATAEATDGTLFAGLIPNALNGLANEFPDFKKRMYEVVEKRYEGALQQGTQHCLGGAILHFAFDQVFTGDHRYFEQGYGLLEEEVFNRTISGNSLLYMDQEYLPDIPIFVYHGSLDGIVPIPDVHGVYKNWCDWGIDSFEFAEDSLNGHLTEIVVGAPAAITWLDARFDGQPVVEGCKKTTRITNFSYPNISDSTRNFFKGILDSLTASQLGPGVTSDNVTLSGLTGFMGGLSKFKKSV", "length": 471, "molWeight": 51226, "crc64": "15AC64A3B11BD868", "md5": "0BF3562C3A29FBCDA4C0F73580CBC3A5"}}
{"primaryAccession": "Q9P8W5", "text": "This is Lipase 2 protein, from Yeast, contains 466 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P8W5", "organism_name": "Yeast", "protein_name": "Lipase 2", "length": 466, "firstPublicDate": "2003-11-21", "SUBCELLULAR LOCATION": "Extracellular", "SIMILARITY": "Belongs to the AB hydrolase superfamily, Lipase family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKGLVFLLGLLPTIYASLVHITPASEDDFYNPPAGFESAKNGDILKLRNSPNRLASFYFPIDVKNAWQLLVKSEDSFGNPNAFVTTLIEPYNADPSKVVSYQTWEDASNINCSPSYGAQFGSPLSTITTQIDMTLIVPPLRSGYYVVTPDYEGPKATFAVGRQSGQATLDSVRAILKSGSFSGINEDAKVALWGYSGGSLATGWAAALQPVYAPELQKNIVGAAVGGFAANITAIAESVDGTIFSGLITLALNGLANEYPDLKTAFYEELSDFAVPEFKAGAENCLAENIFHYPLHQYFTGPKRAFEKGWGLLKEDIFNKSIQDNLLIGLNKTYLPQVPVLIYHGTVDEIIPIKDPHAQYQLWCDWGIESLEFAEDLSTGHLAETFTGAPAALAWIDARFDGKTPIQGCSHTTRLTNLLYPNTSDSTHSYFLGIYQAVFGTPLGPGINGDNITINSGLLGLVSSII", "length": 466, "molWeight": 50422, "crc64": "C4F4C994B761F42C", "md5": "A2618892FA8017A8C96A75001237B123"}}
{"primaryAccession": "Q9SGU2", "text": "This is Auxin-responsive protein SAUR71 protein, from Mouse-ear cress, contains 110 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SGU2", "organism_name": "Mouse-ear cress", "protein_name": "Auxin-responsive protein SAUR71", "length": 110, "firstPublicDate": "2015-05-27", "FUNCTION": "Plays a role in the regulation of cell expansion, root meristem patterning and auxin transport", "SUBCELLULAR LOCATION": "Cytoplasm", "SIMILARITY": "Belongs to the ARG7 family", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKQLIRRLSRVADSTQYSLLRSESQRGRTKKEKHKSWVPEGHVPVYVGHEMERFVVNAELLNHPVFVALLKQSAQEYGYEQQGVLRIPCHVLVFERILESLRLGLADRVT", "length": 110, "molWeight": 12782, "crc64": "186B62F6087EB36A", "md5": "617CE1F222F3B286407A44BFCF6AD181"}}
{"primaryAccession": "Q9SX73", "text": "This is Kinase-interacting family protein protein, from Mouse-ear cress, contains 297 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9SX73", "organism_name": "Mouse-ear cress", "protein_name": "Kinase-interacting family protein", "length": 297, "firstPublicDate": "2015-02-04", "FUNCTION": "May be involved in the receptor-like kinase-mediated signal transduction pathway", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MDASQSPLPQLPSLSDLESRMQVMRVSALDDNQTGETFSQRAEWFYQRSPLLLSLCQDLYDGYATLLDRFNQNPKQVIPHDNDTDTDITSEVESILSFQQMEVSTCDMQKNIEDLVSQLVTANLEKDTAKHILQRREQTLQEACKTIGLLKKLVMLLDMEKEVAVEETANLGHKLTSLLEENRELASEALFMKNEAVKLARCVLKMRDEHFHKMCHLQNQIYELQSSREPVYENESSQSCFGLENSKKKSKKRKMSETRSETGEKMRSKWFKRLNTINPFTKCSITPLSSPLYHAAL", "length": 297, "molWeight": 34190, "crc64": "5721139A4C852F71", "md5": "9D45E696E4AF3CCB3A603F585BA4017F"}}
{"primaryAccession": "Q9USK1", "text": "This is Uncharacterized bolA-like protein C4B3.11c protein, from Fission yeast, contains 116 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9USK1", "organism_name": "Fission yeast", "protein_name": "Uncharacterized bolA-like protein C4B3.11c", "length": 116, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the BolA/IbaG family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MKLAIGRLLSPLFLKNPQKPLIITKRFYSTPGERRIKDILTEKLSPSSLRVIDVSGGCGSMYQVAIKSKAFQGKNTLAQHRLVNSILKEEIRNMHGLNLSTEVEDDISAGGSTTSS", "length": 116, "molWeight": 12743, "crc64": "B906E9D32015CC57", "md5": "FB792ECA4E0FE47F73518B6A3222A890"}}
{"primaryAccession": "Q9UT87", "text": "This is Large ribosomal subunit protein bL19m protein, from Fission yeast, contains 182 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UT87", "organism_name": "Fission yeast", "protein_name": "Large ribosomal subunit protein bL19m", "length": 182, "firstPublicDate": "2008-01-15", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane, bL19m is essential for respiration", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the bacterial ribosomal protein bL19 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFNAKHFFNLGLGFQWLQKRGIGSLKRPYNFPKPVPGPKHKDVLSLFEKKCRSVLDEQSERFKMFHRSQPNRVRPGAVLLVESYSKYPSKDSVNRFAGYLLRIRHRGPKSSILLRNVVMGVGVEYLLPIYSPQIKRIVVLKENGLSKRPRRAYLSYLRQPRFRLPPVESLVRKYIEQNQHKP", "length": 182, "molWeight": 21373, "crc64": "8EC571BC6D46BA7D", "md5": "A41FA03BD3341D17B1387FB53609B2CD"}}
{"primaryAccession": "Q9UTA2", "text": "This is Putative redox protein fmp46, mitochondrial protein, from Fission yeast, contains 121 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UTA2", "organism_name": "Fission yeast", "protein_name": "Putative redox protein fmp46, mitochondrial", "length": 121, "firstPublicDate": "2009-05-05", "FUNCTION": "Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the FMP46 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFGLTTKRILTLFTKKRQTLVEQKLTEYMIAGEKTDNQMLHFKLQVETATPTLDQLNIMLSNIGKDKSDLLVAGATSIEDALTKYQHDNQLFRRPCLVDWDKGKVSPYSILLQTRDFSKLL", "length": 121, "molWeight": 13907, "crc64": "24421BF0DE2F4B9B", "md5": "48CE66F8FE056016B2628017C0D8FA00"}}
{"primaryAccession": "Q9UTK1", "text": "This is Cytochrome c oxidase assembly protein cox16, mitochondrial protein, from Fission yeast, contains 113 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UTK1", "organism_name": "Fission yeast", "protein_name": "Cytochrome c oxidase assembly protein cox16, mitochondrial", "length": 113, "firstPublicDate": "2007-03-20", "FUNCTION": "Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase, May participate in merging the COX1 and COX2 assembly lines", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the COX16 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLFYRFKSWYRLQAKKSPFIYVGLPFLSSVLLVWSCLIPISQVKFNRRDEQVKSLSRDAELDIIKRRRKVDVNEEYYRILLDQLNLQNEEYENKRVKRLKGEPTWEGNSSDKE", "length": 113, "molWeight": 13691, "crc64": "2349FD7F99BD67EC", "md5": "0DC72FBA84D25848FF69A695083725F9"}}
{"primaryAccession": "Q9UTQ5", "text": "This is Uncharacterized J domain-containing protein C1071.09c protein, from Fission yeast, contains 282 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UTQ5", "organism_name": "Fission yeast", "protein_name": "Uncharacterized J domain-containing protein C1071.09c", "length": 282, "firstPublicDate": "2007-11-13", "SUBCELLULAR LOCATION": "Nucleus", "SIMILARITY": "Belongs to the DnaJ family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MAGLLNLCYIKDECQFSLLPLTYSFIKMDIDPYSVLGVEKDASDELIRRAYRKKALQHHPDRIHDEEKKVEARIEFDKVAIAYGVLSDKKRRKHYDKTGQLRETDADIDFDWKEWLDELYQGVVSGETLNEFKASYQYSEEEKCDVLKAYEKGKGSMDVILEEVMCCEISDEDRFRQVINNAIKDGKISKYKRFAPNEKKRKRRAKAAEREAQEAEELSMELGLDENLKKRRKAGASDEEALSALIRSRQKSRMYNLISNLESKYSKSSTKPKKSKKSRSKE", "length": 282, "molWeight": 32850, "crc64": "8E3E012BC79658D6", "md5": "68471280FE9709B3FEAAF8EEB0820293"}}
{"primaryAccession": "Q9UTQ9", "text": "This is Signal peptidase complex subunit 2 protein, from Fission yeast, contains 167 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UTQ9", "organism_name": "Fission yeast", "protein_name": "Signal peptidase complex subunit 2", "length": 167, "firstPublicDate": "2009-02-10", "FUNCTION": "Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum, Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "SIMILARITY": "Belongs to the SPCS2 family", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MPKYNVSDFKSKFDKELTNHFNKNGYKQSFVFEDIRLLIAIACIIPAGLAFGIEYVYGFGVLKSYLKYLLPLYFLASCLLTFWSSVVKGSTVYVATKKERHIKISADTFLPLKNKPLITTKFTVLKNRNAVQLEWSVPVAHIFEEDGQISSATFEAEISKYLSQIEN", "length": 167, "molWeight": 19051, "crc64": "E8A906BBC7F98A74", "md5": "EB58A09D9F57630B0C7BC81142D080BC"}}
{"primaryAccession": "Q9UUC8", "text": "This is Large ribosomal subunit protein mL43 protein, from Fission yeast, contains 145 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UUC8", "organism_name": "Fission yeast", "protein_name": "Large ribosomal subunit protein mL43", "length": 145, "firstPublicDate": "2009-05-05", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane, Also has an extraribosomal function, being essential for mitochondrial genome integrity, May interact with MHR1 to take part in the mtDNA repair mechanism", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mL43 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MMIEIIPKISIPKNGLGSFTRPCRRIEFSYCNWGGSSKGMKEFLSTKLESLAKESQDVEFHVTNRQGKHPLIRAYYNTGREKVICTRKMSASSIFQKAILCRDSDGLKPRLIKYPVESTNPSVRGIWSPFSDQAKPHEIYKKKSP", "length": 145, "molWeight": 16555, "crc64": "C7B341F4A933109E", "md5": "1D7BDB0D70A732307095A33B4F71A286"}}
{"primaryAccession": "Q9UUH8", "text": "This is Uncharacterized protein C630.04c protein, from Fission yeast, contains 166 amino acids, is membrane-bound, locates in Lysosome/Vacuole.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UUH8", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C630.04c", "length": 166, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Lysosome/Vacuole", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MGEEISAIDLVMANDQLVSTSDASDIPYDPYSQFWGKVLVLTFGIICVVFVIFMLHHERIKACRTIISAREQQRTQHSIHRRERSSSGASQQFEHHVRQTDCLPLYEPITALNQQYLKTLPTTSTPPPPAIFDENGEFVGDVPSVAGAIERPPSYESLPAPQNDEV", "length": 166, "molWeight": 18581, "crc64": "7EB5F70943283D8D", "md5": "08323A1ADDE0AA06119F745EC47342B3"}}
{"primaryAccession": "Q9UUJ5", "text": "This is Large ribosomal subunit protein mL59 protein, from Fission yeast, contains 145 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UUJ5", "organism_name": "Fission yeast", "protein_name": "Large ribosomal subunit protein mL59", "length": 145, "firstPublicDate": "2008-10-14", "FUNCTION": "Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane", "SUBCELLULAR LOCATION": "Mitochondrion", "SIMILARITY": "Belongs to the mitochondrion-specific ribosomal protein mL59 family", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MPVFTKEALERLPIQLGNFFKKFPPENPNAWTTNPNRQNPFLATRNPQNGLVINPYYSNRRQAEIYKEARLQNLDNLLPQQMSWQKDSTRHILKGLLNPKGKISERKRDEILENRRLKLSESLKKTSKFKNERQKASKIAKPSPF", "length": 145, "molWeight": 17044, "crc64": "CD93105C21842008", "md5": "DE4110E7A2D90ED1705A0E4FDD510509"}}
{"primaryAccession": "Q9UUK4", "text": "This is Uncharacterized protein C1952.02 protein, from Fission yeast, contains 202 amino acids, locates in Nucleus.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9UUK4", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C1952.02", "length": 202, "firstPublicDate": "2009-05-05", "SUBCELLULAR LOCATION": "Nucleus", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MFSSKRYLNSFGWEEGNALKEGGLTKPILTSRKYNTHGLGAKHDIADQWWDNVFSAQLQSIQVNTDNGKVAVQSNGVSTKLRMAKYHSKYSALSSVFRYAGRLCGTFEEDLVDKSLDSSVSPVSSKKVKVRKTSGKESSKREKSKKKKEKKEKKDKLKKKSKRLKLDDSHTQKRKRKVRDKESKKSSKSGLKKVSGTKKVKA", "length": 202, "molWeight": 22832, "crc64": "491637A8D623D3B1", "md5": "92DA3F5102A0590EF4C98D4E8811CD98"}}
{"primaryAccession": "B3A0Q4", "text": "This is Uncharacterized shell protein 8 protein, from Giant owl limpet, contains 185 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "B3A0Q4", "organism_name": "Giant owl limpet", "protein_name": "Uncharacterized shell protein 8", "length": 185, "firstPublicDate": "2012-01-25", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MGSQKSPYFDANSVFYIGLLYICIYETLAVSWPTNGQQTSWNNRPSYNQYYQYQRAYPGLYNRPTTAPNAYSKNSAAITTRTTYPYYRSSTYNRYPQQQQQQRWGMPRFPAFLPPLRNYQQVNRLEPFLPPPSGDRNIPLTPGVMRMLGISPHGHMMNRMGMNQPYGPDRTVGGITVDGSDVSYA", "length": 185, "molWeight": 21265, "crc64": "2CCEFEFDCC633834", "md5": "77A150C066B105BFC0E6A21F0236341D"}}
{"primaryAccession": "D4AMW3", "text": "This is Uncharacterized secreted protein ARB_05566 protein, from Trichophyton mentagrophytes, contains 190 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4AMW3", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Uncharacterized secreted protein ARB_05566", "length": 190, "firstPublicDate": "2015-11-11", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKVFAYIALATVVAGANIRNHFGDNCKGGYLDYPNIAQRICASALHDKIKGAVTVAFSQLPQHSYMNGYQNTRDGGICGSRQKQQNVGNTDHKCLPKLAGGAEYAGSSWTAPGFKAASEKDMECTSEMAPHALVLNDGHKYALGGMEKDMINTLYSMAIEGKGFQELPTEFGAFEIEKEGAQQRAQEIKA", "length": 190, "molWeight": 20542, "crc64": "E4A3652230A61835", "md5": "EBFC461910DD05E945253E75134E6322"}}
{"primaryAccession": "D4B5D3", "text": "This is Uncharacterized secreted protein ARB_03673 protein, from Trichophyton mentagrophytes, contains 197 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "D4B5D3", "organism_name": "Trichophyton mentagrophytes", "protein_name": "Uncharacterized secreted protein ARB_03673", "length": 197, "firstPublicDate": "2015-11-11", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKLASLLVGSLMLAVPALAFEQSAIQTLRDATTATGAYHSKFPHALSEGPEAAISNINSATARAADEAKTAMTGLTVQSQSLAGALKGVSWISPHVLVVLFMPKYGVLTMFVWQFFDAMTTLSHDATNPAVFCSKNIDRLGPSMGWNLRLPHATTLKRDCKDGEKLVADLAGSYKIAVDSLEQAQAMLESPQGKCKQ", "length": 197, "molWeight": 21039, "crc64": "9B6C7F031149A70D", "md5": "2E12F56712262E3CB4C2C32291F21FA9"}}
{"primaryAccession": "H2A0K6", "text": "This is Valine-rich protein protein, from Freshwater pearl mussel, contains 238 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "H2A0K6", "organism_name": "Freshwater pearl mussel", "protein_name": "Valine-rich protein", "length": 238, "firstPublicDate": "2012-06-13", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MQAVLLVVALFGAALADPPKQIHLPTPKVKRVEKLAHQEHAVNVVQAVPITKTVVRTVNVPKTLIQEVPIHVYTDLVLKSPVPRRKVIDIKKTVLQPHIRHVPVDQPYVVHRRVPVIHTKIVRQPRPVHRIVKIPKLKVVQKQLNRIIDVPQIVTKERIHRVIKPVPVERTRIQHVDVDVPMRVVVPEPVVQDRHTQSVETVPVPHDVVRKVKVPKTFVLKDLIPVPEKAGRHYSSDK", "length": 238, "molWeight": 27150, "crc64": "5018E92991154AD0", "md5": "B6333B3D48E70E5DBD320E09E13D8B63"}}
{"primaryAccession": "H2A0K9", "text": "This is Shematrin-like protein 2 protein, from Freshwater pearl mussel, contains 223 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "H2A0K9", "organism_name": "Freshwater pearl mussel", "protein_name": "Shematrin-like protein 2", "length": 223, "firstPublicDate": "2012-06-13", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRILANLILLGVLFGVCLCQGCGDSDDDGQDDCTGDCGDGDFDGVDDCTGNCGDSDGDGYDDCNDDDSQGAYTYPYGRYLYGRRFGLRRFGNPFFRFRRFGFGPVGGLNFRLGGFGYPYGGYGNLLSRFRGYGGYGNLLGGIRGYGNVLGGYGNVLGGYGNMLGGYGNILGGYGNMLGGYGNLGGYRGYGYQLRGYGGYGSFPDNYGRYSVGSYLRRRRRKKY", "length": 223, "molWeight": 24113, "crc64": "84F39EACBB09045E", "md5": "EF2F56FCB802C4E5D72E329A31029866"}}
{"primaryAccession": "H2A0N6", "text": "This is Uncharacterized shell protein 7 protein, from Freshwater pearl mussel, contains 100 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "H2A0N6", "organism_name": "Freshwater pearl mussel", "protein_name": "Uncharacterized shell protein 7", "length": 100, "firstPublicDate": "2012-06-13", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKYVALAFVLSLVILQISAQVGAAYIPGMGSIGSVGRAGAAAGASAGIGNQGRGAGLLRFFTLILENLMKNNQQAQPKQDNFGAQLQNLLKKKMILEMIN", "length": 100, "molWeight": 10491, "crc64": "4167B0481E06E7EE", "md5": "947B64A917BA361BD0E106680159DEAD"}}
{"primaryAccession": "O14090", "text": "This is Uncharacterized protein C2F3.07c protein, from Fission yeast, contains 101 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O14090", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C2F3.07c", "length": 101, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MLVRENNSNDRSIIEYVIKILLISGISRIIILILAMFESIRHIIFHNDTNPSDARKFQMAICRLSSQKSRKLKNPIESSTTSHKKKGYVRKCYECLQIQVS", "length": 101, "molWeight": 11724, "crc64": "8EB7116DA1DB9508", "md5": "4B33B1728ACE5727DF955EEBC5A44337"}}
{"primaryAccession": "O59779", "text": "This is Uncharacterized protein C1235.01 protein, from Fission yeast, contains 658 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O59779", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C1235.01", "length": 658, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MTATIIAAITITTIVIITPMEEITTMTIPMEEITTMTIPMEEITTMTIPMEEITTMTTPMEEITTITTPMEETTTITPMVETTTILPMAAMTTPMVETTTIPTVETTTTPMVETTTITPMVETTTITPMVEAMITLMEETMTTPMEETTTILPMAAMTTPMEETTTTTPMVETTTIPTVETMTTPMVEAMTILPMAAMTTPMEETTTTPMEETTTTPMVETMITPMVEAMTTPTEVVGRSMVSTIRTTTPMEAMITPTVETTTLPTAAMTTPVEETTTTPMVETMITPTVVTTTTPMVETMITPTVVTTTPMVILVMAVVMETTINIVGNNDSIPSQNFKSGKTFVSNANSSNSNDGSSSKSLDVGSFVNAFKQLNVNDNSSNNNSSGNTDSSTIGYAAVFAAAGKFFSQHSCDLASGNKSAQEGQNQFLSMVESEAKNLMNKTNYSANQSQNGNSQNSGNPVSQAIDLAKSLFQNRNLLTKLAQSGVLTNAAQGSSGGLSAAAVSGLIGSFMGSSSNNSNSSNNNSNTSNNNSNTSNNESMVSKLSSLSGMASSFLGSSGNNNNNNNSNSGNYNNNNSGNNNQQHQQSSSSLQGLASSFLNSSSGNSNKQNYNNNNNQNYGNNNNQNYNNNNNSSQGGNSQGGSGLLGQAVNMFLKS", "length": 658, "molWeight": 69696, "crc64": "63082230B6488AC5", "md5": "6487E35C819F10CDDD533861F6E13585"}}
{"primaryAccession": "O94433", "text": "This is Uncharacterized membrane protein C660.17c protein, from Fission yeast, contains 172 amino acids, is membrane-bound, locates in Endoplasmic reticulum.", "functionDomainRange": [], "meta_data": {"primaryAccession": "O94433", "organism_name": "Fission yeast", "protein_name": "Uncharacterized membrane protein C660.17c", "length": 172, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Endoplasmic reticulum", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MEQLRKRVVRFTNNDDDDFEPVFLNEQDQDAFVEQLRLTNNRDNRMFSIIFSFLYLLLIVPLFLYPEYWAFKLVELLSLFYCAYVMYFLPLEVGLFNPKTPNKWKFLFILNIGVTALITVLGWSQHTSFFYAFLNIRTLVCGITIFTEIARYSMYHSTLSVEKLDEMRFAHM", "length": 172, "molWeight": 20581, "crc64": "0DE99915B478C3F3", "md5": "80FA75668EA8DBBAFB63A2A3A9292BF5"}}
{"primaryAccession": "P40166", "text": "This is Uncharacterized protein YNL198C, mitochondrial protein, from Baker's yeast, contains 100 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P40166", "organism_name": "Baker's yeast", "protein_name": "Uncharacterized protein YNL198C, mitochondrial", "length": 100, "firstPublicDate": "1995-02-01", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MSFNGISIRVITSYFLFFLDNLSKIKFSRLFSFKYRDFCDSCPLDIIIINASIRCLRSVFDFLHILTPRLNGKTTKKPKRNLRTQRVFDEKLHSHNASPN", "length": 100, "molWeight": 11775, "crc64": "B3108EBDFE770D21", "md5": "1B671C9F12ECB1630C8EAAD627F07D19"}}
{"primaryAccession": "P86950", "text": "This is Shematrin-like protein 2 protein, from Silver-lipped pearl oyster, contains 394 amino acids, is soluble, locates in Extracellular.", "functionDomainRange": [], "meta_data": {"primaryAccession": "P86950", "organism_name": "Silver-lipped pearl oyster", "protein_name": "Shematrin-like protein 2", "length": 394, "firstPublicDate": "2011-10-19", "SUBCELLULAR LOCATION": "Extracellular", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MKPFISLASLIVLIASASAGGDDDYGKYGYGSYGPGIGGIGGGGGGIVIGGGGGGIGGGIGGGIGGGIGGGGLIGGGGLIGGFGPGSVSGSVNQFGGVRTRAFGLGGTSPAVRGAAQGAATLSALGVASGRPSRVSGVSVGTGGGRALVSGSATPIGGYGIGIPYGVYGGGYGGYGGGYGGYGLGYGGYGGGYGGYGYGGYGYGPDLATFQGHTFGNLATGSINSLTGGYQIPYGGILSLYGPYGGYGGGYGGYGGGYGGYGGGYGIGIGSGGLGYGGYGYGGYGLGGSTLTGVSQSGPFGTASMYGQAYGAGVPLFGTTYFGGVNVGSPYGIYGGGYPIGGIGGGAGPIGGGGIVIGGGVGGIGGGGIGGIGGGGIGGGGIIGGGPIIRKKKY", "length": 394, "molWeight": 35687, "crc64": "7E8D373FE122EF36", "md5": "BFB09DE577D5072FE3F1C3D4F94FCC95"}}
{"primaryAccession": "Q08909", "text": "This is Uncharacterized protein YOR385W protein, from Baker's yeast, contains 290 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q08909", "organism_name": "Baker's yeast", "protein_name": "Uncharacterized protein YOR385W", "length": 290, "firstPublicDate": "2006-06-27", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MRGFSGQPLSDDDNYRIEKTQRNTIPERLHFSRERNMPIASIFGTRGYFVFSSEQSYDKFKQTNFNISTLDADGVGVPLFHIVQSYNVIGKITRSSPDFYIYKYVLQGVQDPPLYSDCKVICQDKVFRLCKILYCEIYAHQGFFETKYDFFYPSKTQPVKKYQIIKQSNMRDLYSTLDGMRFRWHVKFYSDHFRLMFLDEDRLNYSNSNQKERQKPDQGKSKAPDFVIGHYTRTFSDILPRSTSKCSNLIIGEHSKPDSLGITTVPDLTQEFACQGALIHYLLHIERERK", "length": 290, "molWeight": 34064, "crc64": "475279C95AF9DEAD", "md5": "F52CE923E52E1D51C1207FA08B5AAF8A"}}
{"primaryAccession": "Q9P7D1", "text": "This is Uncharacterized protein P4H10.18c protein, from Fission yeast, contains 314 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7D1", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein P4H10.18c", "length": 314, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MVASLIKRAKATSLRSLFQKNEMNFQSIRFNIHQFSTQPALRSEGSELIFGGRSFDSLLSSIKETMEEKKKKSSSFEKRDKRRVQLKEKSPLRTPRNRTQIIDARSTRKDTENESLRKNNFKRRTQFAFTGRATKSNAGVMDVQSPSTMSTSKNNVRNAERPASKKPVFGSKKYFDVINDSNVENKEETKDRNLDRALSKFTQSREKNEQNLSSKASVLRNKKSILLKKRNQDETQLTTEEDFSANNDSTAKIETSIHDHRDISRITPFELPFVNPKLFASFTPMSVALPAGRLLLIKQLQEKSTQSSSMTGLK", "length": 314, "molWeight": 35880, "crc64": "D8CDC5677625230B", "md5": "DB11C0379C3E09C5C0E404552CD7E8EF"}}
{"primaryAccession": "Q9P7M4", "text": "This is Uncharacterized protein SPAP27G11.14c protein, from Fission yeast, contains 689 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9P7M4", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein SPAP27G11.14c", "length": 689, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNLLSHQLRDRFPIKAIISKADEVIFANYKHTNDFFKITATTYALINSVIVSNNCCNRRFHSTWQKKKHDDLTATVPVIDFRKNQKLTSIVVNAIQAIYWYARRSNCLTGINEAEYIWKSLIPESIFYHFVSLQSFIRKYLTDVFYCSAQKVILLSTDDSVVSSEKLYIRIASILSNANDKVSFKESSINTNTVFKDVYVEVSSHNDEFLLKNSSKCWAFTSLLVDPLHFMFSQIVFEDLSGKKIMKFEDTAVSTASNHSKQFTKGNLLAIKYIGGLYNAVYLMGLKKNLLAFVENEKDDLFVAKIFLLAYSSSKNRKKIVPVDVWDAMIDSLYETINVEETKKETYKFTRSIKTVIPNKLISNESISILSIPESEKTIYQNFDLYVSKFNVARKELSEKELFNNSFSSSFNTLLASLLVKPTLCLISYLMIAKKMVVLQEANRLFLKSFAHPFHLERYHLHAVAAMGGLYQIMSSTHLKNLFFCSRKGIALTKLHSQQYNESTLFQYLSEFVHQRQKSLTPKQRIAIQELILKFMQRNFENSLYHQSFSSHWFISRLLINPIRMLCWHITDVGKTLDLGEAEKLLKYNHKQCPYIIYPSSLKAVQKLGGLQCIIRNDNLSHIFNCSRKYIRVQRYSDDDLSESSLLPRLVNLLLFFENSMGEVAWNKLSQTLMDMFEKETKSNSLSDY", "length": 689, "molWeight": 79764, "crc64": "7C1892D1790A8B07", "md5": "A3C005046AB69E2CAD9DE5A3C00B3ABC"}}
{"primaryAccession": "Q9Y7K5", "text": "This is Uncharacterized WD repeat-containing protein C2A9.03 protein, from Fission yeast, contains 426 amino acids, is soluble, locates in Cytoplasm.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y7K5", "organism_name": "Fission yeast", "protein_name": "Uncharacterized WD repeat-containing protein C2A9.03", "length": 426, "firstPublicDate": "2008-02-05", "SUBCELLULAR LOCATION": "Cytoplasm", "domain_description": {}, "bin_loc": "S", "split": "test"}, "sequence": {"value": "MSNGEFIDQYLLPESGAILQDYLDDYFYTSWYTGNRNLIQLDHYGFPTASNFELNPKSTDNCGTVDFQGIPWGNKAIGKRKNFRLYRLHTYSLSCNHSDWSPEELSLDTVQVAAEDSFYEFQRFLKNPNCLRNHHHLCKSVKVVGEHSVIYVSNNSIRMENTLHDNSVQIIDLKNNILQKKAISCLDTTNAVGCLGTLYGQYCIFNFKNGSFSTRKLSDDSINHIQLFSEKKFILGCNDGAVYVEDVQRTSPILVYRCSNAVNCVQLFDETPLALVCTDSKDAMLIDIRSNSVSAKLPHSDSVLTGSWHPNGNILATGGQDTTAKVWDIRALGKSFRNLGSQMSAVTNLCFSPLGESLAVTEQADFVQLFDTKLFNTSQVIDFFGEIAGTAYSSSGDSLFIGVDDPMLGGILEFRRPLQHPLSFIF", "length": 426, "molWeight": 47652, "crc64": "75B1834077DD0AF2", "md5": "467297DD08F1C7EA2D702F9B7BCC2052"}}
{"primaryAccession": "Q9Y7X4", "text": "This is Uncharacterized membrane protein C365.16 protein, from Fission yeast, contains 277 amino acids, is membrane-bound, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y7X4", "organism_name": "Fission yeast", "protein_name": "Uncharacterized membrane protein C365.16", "length": 277, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "M", "split": "test"}, "sequence": {"value": "MALNSQPPLSPKPVPSNTWKRIGIDAFAATAASAMISPFILTIDRSIVENTSGRSTLLRSVSRSIKYVLSKPGAFFFSAPFALVFTLYSGTYMTANSIDTLDNIRHKNPVFKAETSGWFKFCSVTAANSGLSILKDSFFTKFWGTGSPRPLPWSCYGLYGLRDALTIAFSFNIPPMIAPLLPGGLITAQLLTPCAVQFISTPLHLLSLDIYNRGGPNISAANRVMQVRKHLLKSTFARMVRILPAFGIGGVTNRKLRTTYLDSLQQRTMKKQQFALA", "length": 277, "molWeight": 30407, "crc64": "3F674BBFB1406092", "md5": "4EDEFFBC69B421E1B3B1ACBA26F59390"}}
{"primaryAccession": "Q9Y807", "text": "This is Uncharacterized protein C146.02 protein, from Fission yeast, contains 263 amino acids, locates in Mitochondrion.", "functionDomainRange": [], "meta_data": {"primaryAccession": "Q9Y807", "organism_name": "Fission yeast", "protein_name": "Uncharacterized protein C146.02", "length": 263, "firstPublicDate": "2007-09-11", "SUBCELLULAR LOCATION": "Mitochondrion", "domain_description": {}, "bin_loc": "U", "split": "test"}, "sequence": {"value": "MNGIRKKPATLQLHNIKTSCFIDGSDDQSDRTRSSSGDSTSNSLKLSHHISDELINAIYKELKSPVSPWDKNISQHSPWLLEAASNSIGDSSPLLSPISPLKLRFHKYSVSKQLNSVGKQGFGLSSNHSRYASPSSPARLARGALGEELSNSQYRLECAAIQKLVAQKRANRRSSKSTLKNSANDIEFFDIEEVSSRKGLIDRTPSKRNVTSRVSDAYSRLKSAVKGESSLSFKRNRSKSKRKIQHLGLTEFNGWEHHQCDWL", "length": 263, "molWeight": 29325, "crc64": "5BBD314A683DE033", "md5": "4E495734E6895BA7D85206B8661E296C"}}