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Sep 8

Eir: Thai Medical Large Language Models

We present Eir Thai Medical LLM, a large language model with 8 billion parameters, specifically designed to enhance the accuracy of handling medical tasks in the Thai language. This model focuses on providing clear and easy-to-understand answers for both healthcare professionals and patients, thereby improving the efficiency of diagnosis and treatment processes. Human evaluation was conducted to ensure that the model adheres to care standards and provides unbiased answers. To prioritize data security, the model is deployed within the hospital's internal network, ensuring both high security and faster processing speeds. The internal API connection is secured with encryption and strict authentication measures to prevent data leaks and unauthorized access. We evaluated several open-source large language models with 8 billion parameters on four medical benchmarks: MedQA, MedMCQA, PubMedQA, and the medical subset of MMLU. The best-performing baselines were used to develop Eir Thai Medical LLM. Our evaluation employed multiple questioning strategies, including zero-shot, few-shot, chain-of-thought reasoning, and ensemble/self-consistency voting methods. Our model outperformed commercially available Thai-language large language models by more than 10%. In addition, we developed enhanced model testing tailored for clinical use in Thai across 18 clinical tasks, where our model exceeded GPT-4o performance by more than 11%

NitiBench: A Comprehensive Studies of LLM Frameworks Capabilities for Thai Legal Question Answering

The application of large language models (LLMs) in the legal domain holds significant potential for information retrieval and question answering, yet Thai legal QA systems face challenges due to a lack of standardized evaluation benchmarks and the complexity of Thai legal structures. This paper introduces NitiBench, a benchmark comprising two datasets: the NitiBench-CCL, covering general Thai financial law, and the NitiBench-Tax, which includes real-world tax law cases requiring advanced legal reasoning. We evaluate retrieval-augmented generation (RAG) and long-context LLM-based approaches to address three key research questions: the impact of domain-specific components like section-based chunking and cross-referencing, the comparative performance of different retrievers and LLMs, and the viability of long-context LLMs as an alternative to RAG. Our results show that section-based chunking significantly improves retrieval and end-to-end performance, current retrievers struggle with complex queries, and long-context LLMs still underperform RAG-based systems in Thai legal QA. To support fair evaluation, we propose tailored multi-label retrieval metrics and the use of an LLM-as-judge for coverage and contradiction detection method. These findings highlight the limitations of current Thai legal NLP solutions and provide a foundation for future research in the field. We also open-sourced our codes and dataset to available publicly.

ViFactCheck: A New Benchmark Dataset and Methods for Multi-domain News Fact-Checking in Vietnamese

The rapid spread of information in the digital age highlights the critical need for effective fact-checking tools, particularly for languages with limited resources, such as Vietnamese. In response to this challenge, we introduce ViFactCheck, the first publicly available benchmark dataset designed specifically for Vietnamese fact-checking across multiple online news domains. This dataset contains 7,232 human-annotated pairs of claim-evidence combinations sourced from reputable Vietnamese online news, covering 12 diverse topics. It has been subjected to a meticulous annotation process to ensure high quality and reliability, achieving a Fleiss Kappa inter-annotator agreement score of 0.83. Our evaluation leverages state-of-the-art pre-trained and large language models, employing fine-tuning and prompting techniques to assess performance. Notably, the Gemma model demonstrated superior effectiveness, with an impressive macro F1 score of 89.90%, thereby establishing a new standard for fact-checking benchmarks. This result highlights the robust capabilities of Gemma in accurately identifying and verifying facts in Vietnamese. To further promote advances in fact-checking technology and improve the reliability of digital media, we have made the ViFactCheck dataset, model checkpoints, fact-checking pipelines, and source code freely available on GitHub. This initiative aims to inspire further research and enhance the accuracy of information in low-resource languages.

One Thousand and One Pairs: A "novel" challenge for long-context language models

Synthetic long-context LLM benchmarks (e.g., "needle-in-the-haystack") test only surface-level retrieval capabilities, but how well can long-context LLMs retrieve, synthesize, and reason over information across book-length inputs? We address this question by creating NoCha, a dataset of 1,001 minimally different pairs of true and false claims about 67 recently-published English fictional books, written by human readers of those books. In contrast to existing long-context benchmarks, our annotators confirm that the largest share of pairs in NoCha require global reasoning over the entire book to verify. Our experiments show that while human readers easily perform this task, it is enormously challenging for all ten long-context LLMs that we evaluate: no open-weight model performs above random chance (despite their strong performance on synthetic benchmarks), while GPT-4o achieves the highest accuracy at 55.8%. Further analysis reveals that (1) on average, models perform much better on pairs that require only sentence-level retrieval vs. global reasoning; (2) model-generated explanations for their decisions are often inaccurate even for correctly-labeled claims; and (3) models perform substantially worse on speculative fiction books that contain extensive world-building. The methodology proposed in NoCha allows for the evolution of the benchmark dataset and the easy analysis of future models.

Integrating Biological Knowledge for Robust Microscopy Image Profiling on De Novo Cell Lines

High-throughput screening techniques, such as microscopy imaging of cellular responses to genetic and chemical perturbations, play a crucial role in drug discovery and biomedical research. However, robust perturbation screening for de novo cell lines remains challenging due to the significant morphological and biological heterogeneity across cell lines. To address this, we propose a novel framework that integrates external biological knowledge into existing pretraining strategies to enhance microscopy image profiling models. Our approach explicitly disentangles perturbation-specific and cell line-specific representations using external biological information. Specifically, we construct a knowledge graph leveraging protein interaction data from STRING and Hetionet databases to guide models toward perturbation-specific features during pretraining. Additionally, we incorporate transcriptomic features from single-cell foundation models to capture cell line-specific representations. By learning these disentangled features, our method improves the generalization of imaging models to de novo cell lines. We evaluate our framework on the RxRx database through one-shot fine-tuning on an RxRx1 cell line and few-shot fine-tuning on cell lines from the RxRx19a dataset. Experimental results demonstrate that our method enhances microscopy image profiling for de novo cell lines, highlighting its effectiveness in real-world phenotype-based drug discovery applications.

BEARCUBS: A benchmark for computer-using web agents

Modern web agents possess computer use abilities that allow them to interact with webpages by sending commands to a virtual keyboard and mouse. While such agents have considerable potential to assist human users with complex tasks, evaluating their capabilities in real-world settings poses a major challenge. To this end, we introduce BEARCUBS, a "small but mighty" benchmark of 111 information-seeking questions designed to evaluate a web agent's ability to search, browse, and identify factual information from the web. Unlike prior web agent benchmarks, solving BEARCUBS requires (1) accessing live web content rather than synthetic or simulated pages, which captures the unpredictability of real-world web interactions; and (2) performing a broad range of multimodal interactions (e.g., video understanding, 3D navigation) that cannot be bypassed via text-based workarounds. Each question in BEARCUBS has a corresponding short, unambiguous answer and a human-validated browsing trajectory, allowing for transparent evaluation of agent performance and strategies. A human study confirms that BEARCUBS questions are solvable but non-trivial (84.7% human accuracy), revealing search inefficiencies and domain knowledge gaps as common failure points. By contrast, state-of-the-art computer-using agents underperform, with the best-scoring system (OpenAI's Operator) reaching only 24.3% accuracy. These results highlight critical areas for improvement, including reliable source selection and more powerful multimodal capabilities. To facilitate future research, BEARCUBS will be updated periodically to replace invalid or contaminated questions, keeping the benchmark fresh for future generations of web agents.

TopRoBERTa: Topology-Aware Authorship Attribution of Deepfake Texts

Recent advances in Large Language Models (LLMs) have enabled the generation of open-ended high-quality texts, that are non-trivial to distinguish from human-written texts. We refer to such LLM-generated texts as deepfake texts. There are currently over 11K text generation models in the huggingface model repo. As such, users with malicious intent can easily use these open-sourced LLMs to generate harmful texts and misinformation at scale. To mitigate this problem, a computational method to determine if a given text is a deepfake text or not is desired--i.e., Turing Test (TT). In particular, in this work, we investigate the more general version of the problem, known as Authorship Attribution (AA), in a multi-class setting--i.e., not only determining if a given text is a deepfake text or not but also being able to pinpoint which LLM is the author. We propose TopRoBERTa to improve existing AA solutions by capturing more linguistic patterns in deepfake texts by including a Topological Data Analysis (TDA) layer in the RoBERTa model. We show the benefits of having a TDA layer when dealing with noisy, imbalanced, and heterogeneous datasets, by extracting TDA features from the reshaped pooled_output of RoBERTa as input. We use RoBERTa to capture contextual representations (i.e., semantic and syntactic linguistic features), while using TDA to capture the shape and structure of data (i.e., linguistic structures). Finally, TopRoBERTa, outperforms the vanilla RoBERTa in 2/3 datasets, achieving up to 7\% increase in Macro F1 score.

TransICD: Transformer Based Code-wise Attention Model for Explainable ICD Coding

International Classification of Disease (ICD) coding procedure which refers to tagging medical notes with diagnosis codes has been shown to be effective and crucial to the billing system in medical sector. Currently, ICD codes are assigned to a clinical note manually which is likely to cause many errors. Moreover, training skilled coders also requires time and human resources. Therefore, automating the ICD code determination process is an important task. With the advancement of artificial intelligence theory and computational hardware, machine learning approach has emerged as a suitable solution to automate this process. In this project, we apply a transformer-based architecture to capture the interdependence among the tokens of a document and then use a code-wise attention mechanism to learn code-specific representations of the entire document. Finally, they are fed to separate dense layers for corresponding code prediction. Furthermore, to handle the imbalance in the code frequency of clinical datasets, we employ a label distribution aware margin (LDAM) loss function. The experimental results on the MIMIC-III dataset show that our proposed model outperforms other baselines by a significant margin. In particular, our best setting achieves a micro-AUC score of 0.923 compared to 0.868 of bidirectional recurrent neural networks. We also show that by using the code-wise attention mechanism, the model can provide more insights about its prediction, and thus it can support clinicians to make reliable decisions. Our code is available online (https://github.com/biplob1ly/TransICD)

Neural Brain: A Neuroscience-inspired Framework for Embodied Agents

The rapid evolution of artificial intelligence (AI) has shifted from static, data-driven models to dynamic systems capable of perceiving and interacting with real-world environments. Despite advancements in pattern recognition and symbolic reasoning, current AI systems, such as large language models, remain disembodied, unable to physically engage with the world. This limitation has driven the rise of embodied AI, where autonomous agents, such as humanoid robots, must navigate and manipulate unstructured environments with human-like adaptability. At the core of this challenge lies the concept of Neural Brain, a central intelligence system designed to drive embodied agents with human-like adaptability. A Neural Brain must seamlessly integrate multimodal sensing and perception with cognitive capabilities. Achieving this also requires an adaptive memory system and energy-efficient hardware-software co-design, enabling real-time action in dynamic environments. This paper introduces a unified framework for the Neural Brain of embodied agents, addressing two fundamental challenges: (1) defining the core components of Neural Brain and (2) bridging the gap between static AI models and the dynamic adaptability required for real-world deployment. To this end, we propose a biologically inspired architecture that integrates multimodal active sensing, perception-cognition-action function, neuroplasticity-based memory storage and updating, and neuromorphic hardware/software optimization. Furthermore, we also review the latest research on embodied agents across these four aspects and analyze the gap between current AI systems and human intelligence. By synthesizing insights from neuroscience, we outline a roadmap towards the development of generalizable, autonomous agents capable of human-level intelligence in real-world scenarios.

MiniCPM: Unveiling the Potential of Small Language Models with Scalable Training Strategies

The burgeoning interest in developing Large Language Models (LLMs) with up to trillion parameters has been met with concerns regarding resource efficiency and practical expense, particularly given the immense cost of experimentation. This scenario underscores the importance of exploring the potential of Small Language Models (SLMs) as a resource-efficient alternative. In this context, we introduce MiniCPM, specifically the 1.2B and 2.4B non-embedding parameter variants, not only excel in their respective categories but also demonstrate capabilities on par with 7B-13B LLMs. While focusing on SLMs, our approach exhibits scalability in both model and data dimensions for future LLM research. Regarding model scaling, we employ extensive model wind tunnel experiments for stable and optimal scaling. For data scaling, we introduce a Warmup-Stable-Decay (WSD) learning rate scheduler (LRS), conducive to continuous training and domain adaptation. We present an in-depth analysis of the intriguing training dynamics that occurred in the WSD LRS. With WSD LRS, we are now able to efficiently study data-model scaling law without extensive retraining experiments on both axes of model and data, from which we derive the much higher compute optimal data-model ratio than Chinchilla Optimal. Additionally, we introduce MiniCPM family, including MiniCPM-DPO, MiniCPM-MoE and MiniCPM-128K, whose excellent performance further cementing MiniCPM's foundation in diverse SLM applications. MiniCPM models are available publicly at https://github.com/OpenBMB/MiniCPM .

APIGen-MT: Agentic Pipeline for Multi-Turn Data Generation via Simulated Agent-Human Interplay

Training effective AI agents for multi-turn interactions requires high-quality data that captures realistic human-agent dynamics, yet such data is scarce and expensive to collect manually. We introduce APIGen-MT, a two-phase framework that generates verifiable and diverse multi-turn agent data. In the first phase, our agentic pipeline produces detailed task blueprints with ground-truth actions, leveraging a committee of LLM reviewers and iterative feedback loops. These blueprints are then transformed into complete interaction trajectories through simulated human-agent interplay. We train a family of models -- the xLAM-2-fc-r series with sizes ranging from 1B to 70B parameters. Our models outperform frontier models such as GPT-4o and Claude 3.5 on tau-bench and BFCL benchmarks, with the smaller models surpassing their larger counterparts, particularly in multi-turn settings, while maintaining superior consistency across multiple trials. Comprehensive experiments demonstrate that our verified blueprint-to-details approach yields high-quality training data, enabling the development of more reliable, efficient, and capable agents. We open-source both the synthetic data collected and the trained xLAM-2-fc-r models to advance research in AI agents. Models are available on HuggingFace at https://huggingface.co/collections/Salesforce/xlam-2-67ef5be12949d8dcdae354c4 and project website is https://apigen-mt.github.io

Sloan Digital Sky Survey IV: Mapping the Milky Way, Nearby Galaxies, and the Distant Universe

We describe the Sloan Digital Sky Survey IV (SDSS-IV), a project encompassing three major spectroscopic programs. The Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2) is observing hundreds of thousands of Milky Way stars at high resolution and high signal-to-noise ratio in the near-infrared. The Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey is obtaining spatially-resolved spectroscopy for thousands of nearby galaxies (median redshift of z = 0.03). The extended Baryon Oscillation Spectroscopic Survey (eBOSS) is mapping the galaxy, quasar, and neutral gas distributions between redshifts z = 0.6 and 3.5 to constrain cosmology using baryon acoustic oscillations, redshift space distortions, and the shape of the power spectrum. Within eBOSS, we are conducting two major subprograms: the SPectroscopic IDentification of eROSITA Sources (SPIDERS), investigating X-ray AGN and galaxies in X-ray clusters, and the Time Domain Spectroscopic Survey (TDSS), obtaining spectra of variable sources. All programs use the 2.5-meter Sloan Foundation Telescope at Apache Point Observatory; observations there began in Summer 2014. APOGEE-2 also operates a second near-infrared spectrograph at the 2.5-meter du Pont Telescope at Las Campanas Observatory, with observations beginning in early 2017. Observations at both facilities are scheduled to continue through 2020. In keeping with previous SDSS policy, SDSS-IV provides regularly scheduled public data releases; the first one, Data Release 13, was made available in July 2016.