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Nov 28

Clinical Text Summarization: Adapting Large Language Models Can Outperform Human Experts

Sifting through vast textual data and summarizing key information imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown immense promise in natural language processing (NLP) tasks, their efficacy across diverse clinical summarization tasks has not yet been rigorously examined. In this work, we employ domain adaptation methods on eight LLMs, spanning six datasets and four distinct summarization tasks: radiology reports, patient questions, progress notes, and doctor-patient dialogue. Our thorough quantitative assessment reveals trade-offs between models and adaptation methods in addition to instances where recent advances in LLMs may not lead to improved results. Further, in a clinical reader study with six physicians, we depict that summaries from the best adapted LLM are preferable to human summaries in terms of completeness and correctness. Our ensuing qualitative analysis delineates mutual challenges faced by both LLMs and human experts. Lastly, we correlate traditional quantitative NLP metrics with reader study scores to enhance our understanding of how these metrics align with physician preferences. Our research marks the first evidence of LLMs outperforming human experts in clinical text summarization across multiple tasks. This implies that integrating LLMs into clinical workflows could alleviate documentation burden, empowering clinicians to focus more on personalized patient care and other irreplaceable human aspects of medicine.

  • 15 authors
·
Sep 14, 2023 4

Emotion-Qwen: Training Hybrid Experts for Unified Emotion and General Vision-Language Understanding

Emotion understanding in videos aims to accurately recognize and interpret individuals' emotional states by integrating contextual, visual, textual, and auditory cues. While Large Multimodal Models (LMMs) have demonstrated significant progress in general vision-language (VL) tasks, their performance in emotion-specific scenarios remains limited. Moreover, fine-tuning LMMs on emotion-related tasks often leads to catastrophic forgetting, hindering their ability to generalize across diverse tasks. To address these challenges, we present Emotion-Qwen, a tailored multimodal framework designed to enhance both emotion understanding and general VL reasoning. Emotion-Qwen incorporates a sophisticated Hybrid Compressor based on the Mixture of Experts (MoE) paradigm, which dynamically routes inputs to balance emotion-specific and general-purpose processing. The model is pre-trained in a three-stage pipeline on large-scale general and emotional image datasets to support robust multimodal representations. Furthermore, we construct the Video Emotion Reasoning (VER) dataset, comprising more than 40K bilingual video clips with fine-grained descriptive annotations, to further enrich Emotion-Qwen's emotional reasoning capability. Experimental results demonstrate that Emotion-Qwen achieves state-of-the-art performance on multiple emotion recognition benchmarks, while maintaining competitive results on general VL tasks. Code and models are available at https://github.com/24DavidHuang/Emotion-Qwen.

  • 10 authors
·
May 10

Test-Time Scaling in Diffusion LLMs via Hidden Semi-Autoregressive Experts

Diffusion-based large language models (dLLMs) are trained flexibly to model extreme dependence in the data distribution; however, how to best utilize this information at inference time remains an open problem. In this work, we uncover an interesting property of these models: dLLMs trained on textual data implicitly learn a mixture of semi-autoregressive experts, where different generation orders reveal different specialized behaviors. We show that committing to any single, fixed inference time schedule, a common practice, collapses performance by failing to leverage this latent ensemble. To address this, we introduce HEX (Hidden semiautoregressive EXperts for test-time scaling), a training-free inference method that ensembles across heterogeneous block schedules. By doing a majority vote over diverse block-sized generation paths, HEX robustly avoids failure modes associated with any single fixed schedule. On reasoning benchmarks such as GSM8K, it boosts accuracy by up to 3.56X (from 24.72% to 88.10%), outperforming top-K margin inference and specialized fine-tuned methods like GRPO, without additional training. HEX even yields significant gains on MATH benchmark from 16.40% to 40.00%, scientific reasoning on ARC-C from 54.18% to 87.80%, and TruthfulQA from 28.36% to 57.46%. Our results establish a new paradigm for test-time scaling in diffusion-based LLMs (dLLMs), revealing that the sequence in which masking is performed plays a critical role in determining performance during inference.

REMOTE: A Unified Multimodal Relation Extraction Framework with Multilevel Optimal Transport and Mixture-of-Experts

Multimodal relation extraction (MRE) is a crucial task in the fields of Knowledge Graph and Multimedia, playing a pivotal role in multimodal knowledge graph construction. However, existing methods are typically limited to extracting a single type of relational triplet, which restricts their ability to extract triplets beyond the specified types. Directly combining these methods fails to capture dynamic cross-modal interactions and introduces significant computational redundancy. Therefore, we propose a novel unified multimodal Relation Extraction framework with Multilevel Optimal Transport and mixture-of-Experts, termed REMOTE, which can simultaneously extract intra-modal and inter-modal relations between textual entities and visual objects. To dynamically select optimal interaction features for different types of relational triplets, we introduce mixture-of-experts mechanism, ensuring the most relevant modality information is utilized. Additionally, considering that the inherent property of multilayer sequential encoding in existing encoders often leads to the loss of low-level information, we adopt a multilevel optimal transport fusion module to preserve low-level features while maintaining multilayer encoding, yielding more expressive representations. Correspondingly, we also create a Unified Multimodal Relation Extraction (UMRE) dataset to evaluate the effectiveness of our framework, encompassing diverse cases where the head and tail entities can originate from either text or image. Extensive experiments show that REMOTE effectively extracts various types of relational triplets and achieves state-of-the-art performanc on almost all metrics across two other public MRE datasets. We release our resources at https://github.com/Nikol-coder/REMOTE.

  • 7 authors
·
Sep 5

Parrot: Multilingual Visual Instruction Tuning

The rapid development of Multimodal Large Language Models (MLLMs) like GPT-4V has marked a significant step towards artificial general intelligence. Existing methods mainly focus on aligning vision encoders with LLMs through supervised fine-tuning (SFT) to endow LLMs with multimodal abilities, making MLLMs' inherent ability to react to multiple languages progressively deteriorate as the training process evolves. We empirically find that the imbalanced SFT datasets, primarily composed of English-centric image-text pairs, lead to significantly reduced performance in non-English languages. This is due to the failure of aligning the vision encoder and LLM with multilingual tokens during the SFT process. In this paper, we introduce Parrot, a novel method that utilizes textual guidance to drive visual token alignment at the language level. Parrot makes the visual tokens condition on diverse language inputs and uses Mixture-of-Experts (MoE) to promote the alignment of multilingual tokens. Specifically, to enhance non-English visual tokens alignment, we compute the cross-attention using the initial visual features and textual embeddings, the result of which is then fed into the MoE router to select the most relevant experts. The selected experts subsequently convert the initial visual tokens into language-specific visual tokens. Moreover, considering the current lack of benchmarks for evaluating multilingual capabilities within the field, we collect and make available a Massive Multilingual Multimodal Benchmark which includes 6 languages, 15 categories, and 12,000 questions, named as MMMB. Our method not only demonstrates state-of-the-art performance on multilingual MMBench and MMMB, but also excels across a broad range of multimodal tasks. Both the source code and the training dataset of Parrot will be made publicly available.

  • 11 authors
·
Jun 4, 2024 2

HOIGen-1M: A Large-scale Dataset for Human-Object Interaction Video Generation

Text-to-video (T2V) generation has made tremendous progress in generating complicated scenes based on texts. However, human-object interaction (HOI) often cannot be precisely generated by current T2V models due to the lack of large-scale videos with accurate captions for HOI. To address this issue, we introduce HOIGen-1M, the first largescale dataset for HOI Generation, consisting of over one million high-quality videos collected from diverse sources. In particular, to guarantee the high quality of videos, we first design an efficient framework to automatically curate HOI videos using the powerful multimodal large language models (MLLMs), and then the videos are further cleaned by human annotators. Moreover, to obtain accurate textual captions for HOI videos, we design a novel video description method based on a Mixture-of-Multimodal-Experts (MoME) strategy that not only generates expressive captions but also eliminates the hallucination by individual MLLM. Furthermore, due to the lack of an evaluation framework for generated HOI videos, we propose two new metrics to assess the quality of generated videos in a coarse-to-fine manner. Extensive experiments reveal that current T2V models struggle to generate high-quality HOI videos and confirm that our HOIGen-1M dataset is instrumental for improving HOI video generation. Project webpage is available at https://liuqi-creat.github.io/HOIGen.github.io.

  • 8 authors
·
Mar 31

BREEN: Bridge Data-Efficient Encoder-Free Multimodal Learning with Learnable Queries

Encoder-free multimodal large language models(MLLMs) eliminate the need for a well-trained vision encoder by directly processing image tokens before the language model. While this approach reduces computational overhead and model complexity, it often requires large amounts of training data to effectively capture the visual knowledge typically encoded by vision models like CLIP. The absence of a vision encoder implies that the model is likely to rely on substantial data to learn the necessary visual-semantic alignments. In this work, we present BREEN, a data-efficient encoder-free multimodal architecture that mitigates this issue. BREEN leverages a learnable query and image experts to achieve comparable performance with significantly less training data. The learnable query, positioned between image and text tokens, is supervised by the output of a pretrained CLIP model to distill visual knowledge, bridging the gap between visual and textual modalities. Additionally, the image expert processes image tokens and learnable queries independently, improving efficiency and reducing interference with the LLM's textual capabilities. BREEN achieves comparable performance to prior encoder-free state-of-the-art models like Mono-InternVL, using only 13 million text-image pairs in training about one percent of the data required by existing methods. Our work highlights a promising direction for data-efficient encoder-free multimodal learning, offering an alternative to traditional encoder-based approaches.

  • 4 authors
·
Mar 16

Towards LLM-guided Causal Explainability for Black-box Text Classifiers

With the advent of larger and more complex deep learning models, such as in Natural Language Processing (NLP), model qualities like explainability and interpretability, albeit highly desirable, are becoming harder challenges to tackle and solve. For example, state-of-the-art models in text classification are black-box by design. Although standard explanation methods provide some degree of explainability, these are mostly correlation-based methods and do not provide much insight into the model. The alternative of causal explainability is more desirable to achieve but extremely challenging in NLP due to a variety of reasons. Inspired by recent endeavors to utilize Large Language Models (LLMs) as experts, in this work, we aim to leverage the instruction-following and textual understanding capabilities of recent state-of-the-art LLMs to facilitate causal explainability via counterfactual explanation generation for black-box text classifiers. To do this, we propose a three-step pipeline via which, we use an off-the-shelf LLM to: (1) identify the latent or unobserved features in the input text, (2) identify the input features associated with the latent features, and finally (3) use the identified input features to generate a counterfactual explanation. We experiment with our pipeline on multiple NLP text classification datasets, with several recent LLMs, and present interesting and promising findings.

  • 4 authors
·
Sep 23, 2023

UniBiomed: A Universal Foundation Model for Grounded Biomedical Image Interpretation

Multi-modal interpretation of biomedical images opens up novel opportunities in biomedical image analysis. Conventional AI approaches typically rely on disjointed training, i.e., Large Language Models (LLMs) for clinical text generation and segmentation models for target extraction, which results in inflexible real-world deployment and a failure to leverage holistic biomedical information. To this end, we introduce UniBiomed, the first universal foundation model for grounded biomedical image interpretation. UniBiomed is based on a novel integration of Multi-modal Large Language Model (MLLM) and Segment Anything Model (SAM), which effectively unifies the generation of clinical texts and the segmentation of corresponding biomedical objects for grounded interpretation. In this way, UniBiomed is capable of tackling a wide range of biomedical tasks across ten diverse biomedical imaging modalities. To develop UniBiomed, we curate a large-scale dataset comprising over 27 million triplets of images, annotations, and text descriptions across ten imaging modalities. Extensive validation on 84 internal and external datasets demonstrated that UniBiomed achieves state-of-the-art performance in segmentation, disease recognition, region-aware diagnosis, visual question answering, and report generation. Moreover, unlike previous models that rely on clinical experts to pre-diagnose images and manually craft precise textual or visual prompts, UniBiomed can provide automated and end-to-end grounded interpretation for biomedical image analysis. This represents a novel paradigm shift in clinical workflows, which will significantly improve diagnostic efficiency. In summary, UniBiomed represents a novel breakthrough in biomedical AI, unlocking powerful grounded interpretation capabilities for more accurate and efficient biomedical image analysis.

  • 5 authors
·
Apr 30 4

Small but Mighty: Enhancing Time Series Forecasting with Lightweight LLMs

While LLMs have demonstrated remarkable potential in time series forecasting, their practical deployment remains constrained by excessive computational demands and memory footprints. Existing LLM-based approaches typically suffer from three critical limitations: Inefficient parameter utilization in handling numerical time series patterns; Modality misalignment between continuous temporal signals and discrete text embeddings; and Inflexibility for real-time expert knowledge integration. We present SMETimes, the first systematic investigation of sub-3B parameter SLMs for efficient and accurate time series forecasting. Our approach centers on three key innovations: A statistically-enhanced prompting mechanism that bridges numerical time series with textual semantics through descriptive statistical features; A adaptive fusion embedding architecture that aligns temporal patterns with language model token spaces through learnable parameters; And a dynamic mixture-of-experts framework enabled by SLMs' computational efficiency, adaptively combining base predictions with domain-specific models. Extensive evaluations across seven benchmark datasets demonstrate that our 3B-parameter SLM achieves state-of-the-art performance on five primary datasets while maintaining 3.8x faster training and 5.2x lower memory consumption compared to 7B-parameter LLM baselines. Notably, the proposed model exhibits better learning capabilities, achieving 12.3% lower MSE than conventional LLM. Ablation studies validate that our statistical prompting and cross-modal fusion modules respectively contribute 15.7% and 18.2% error reduction in long-horizon forecasting tasks. By redefining the efficiency-accuracy trade-off landscape, this work establishes SLMs as viable alternatives to resource-intensive LLMs for practical time series forecasting. Code and models are available at https://github.com/xiyan1234567/SMETimes.

  • 4 authors
·
Mar 5

InstructVLA: Vision-Language-Action Instruction Tuning from Understanding to Manipulation

To operate effectively in the real world, robots must integrate multimodal reasoning with precise action generation. However, existing vision-language-action (VLA) models often sacrifice one for the other, narrow their abilities to task-specific manipulation data, and suffer catastrophic forgetting of pre-trained vision-language capabilities. To bridge this gap, we introduce InstructVLA, an end-to-end VLA model that preserves the flexible reasoning of large vision-language models (VLMs) while delivering leading manipulation performance. InstructVLA introduces a novel training paradigm, Vision-Language-Action Instruction Tuning (VLA-IT), which employs multimodal training with mixture-of-experts adaptation to jointly optimize textual reasoning and action generation on both standard VLM corpora and a curated 650K-sample VLA-IT dataset. On in-domain SimplerEnv tasks, InstructVLA achieves 30.5% improvement over SpatialVLA. To evaluate generalization, we introduce SimplerEnv-Instruct, an 80-task benchmark requiring closed-loop control and high-level instruction understanding, where it outperforms a fine-tuned OpenVLA by 92% and an action expert aided by GPT-4o by 29%. Additionally, InstructVLA surpasses baseline VLMs on multimodal tasks and exhibits inference-time scaling by leveraging textual reasoning to boost manipulation performance in both simulated and real-world settings. These results demonstrate InstructVLA's potential for bridging intuitive and steerable human-robot interaction with efficient policy learning.

  • 10 authors
·
Jul 23 1

Visual Programming for Text-to-Image Generation and Evaluation

As large language models have demonstrated impressive performance in many domains, recent works have adopted language models (LMs) as controllers of visual modules for vision-and-language tasks. While existing work focuses on equipping LMs with visual understanding, we propose two novel interpretable/explainable visual programming frameworks for text-to-image (T2I) generation and evaluation. First, we introduce VPGen, an interpretable step-by-step T2I generation framework that decomposes T2I generation into three steps: object/count generation, layout generation, and image generation. We employ an LM to handle the first two steps (object/count generation and layout generation), by finetuning it on text-layout pairs. Our step-by-step T2I generation framework provides stronger spatial control than end-to-end models, the dominant approach for this task. Furthermore, we leverage the world knowledge of pretrained LMs, overcoming the limitation of previous layout-guided T2I works that can only handle predefined object classes. We demonstrate that our VPGen has improved control in counts/spatial relations/scales of objects than state-of-the-art T2I generation models. Second, we introduce VPEval, an interpretable and explainable evaluation framework for T2I generation based on visual programming. Unlike previous T2I evaluations with a single scoring model that is accurate in some skills but unreliable in others, VPEval produces evaluation programs that invoke a set of visual modules that are experts in different skills, and also provides visual+textual explanations of the evaluation results. Our analysis shows VPEval provides a more human-correlated evaluation for skill-specific and open-ended prompts than widely used single model-based evaluation. We hope our work encourages future progress on interpretable/explainable generation and evaluation for T2I models. Website: https://vp-t2i.github.io

  • 3 authors
·
May 24, 2023

A Foundation LAnguage-Image model of the Retina (FLAIR): Encoding expert knowledge in text supervision

Foundation vision-language models are currently transforming computer vision, and are on the rise in medical imaging fueled by their very promising generalization capabilities. However, the initial attempts to transfer this new paradigm to medical imaging have shown less impressive performances than those observed in other domains, due to the significant domain shift and the complex, expert domain knowledge inherent to medical-imaging tasks. Motivated by the need for domain-expert foundation models, we present FLAIR, a pre-trained vision-language model for universal retinal fundus image understanding. To this end, we compiled 37 open-access, mostly categorical fundus imaging datasets from various sources, with up to 97 different target conditions and 284,660 images. We integrate the expert's domain knowledge in the form of descriptive textual prompts, during both pre-training and zero-shot inference, enhancing the less-informative categorical supervision of the data. Such a textual expert's knowledge, which we compiled from the relevant clinical literature and community standards, describes the fine-grained features of the pathologies as well as the hierarchies and dependencies between them. We report comprehensive evaluations, which illustrate the benefit of integrating expert knowledge and the strong generalization capabilities of FLAIR under difficult scenarios with domain shifts or unseen categories. When adapted with a lightweight linear probe, FLAIR outperforms fully-trained, dataset-focused models, more so in the few-shot regimes. Interestingly, FLAIR outperforms by a large margin more generalist, larger-scale image-language models, which emphasizes the potential of embedding experts' domain knowledge and the limitations of generalist models in medical imaging.

  • 5 authors
·
Aug 15, 2023

UrFound: Towards Universal Retinal Foundation Models via Knowledge-Guided Masked Modeling

Retinal foundation models aim to learn generalizable representations from diverse retinal images, facilitating label-efficient model adaptation across various ophthalmic tasks. Despite their success, current retinal foundation models are generally restricted to a single imaging modality, such as Color Fundus Photography (CFP) or Optical Coherence Tomography (OCT), limiting their versatility. Moreover, these models may struggle to fully leverage expert annotations and overlook the valuable domain knowledge essential for domain-specific representation learning. To overcome these limitations, we introduce UrFound, a retinal foundation model designed to learn universal representations from both multimodal retinal images and domain knowledge. UrFound is equipped with a modality-agnostic image encoder and accepts either CFP or OCT images as inputs. To integrate domain knowledge into representation learning, we encode expert annotation in text supervision and propose a knowledge-guided masked modeling strategy for model pre-training. It involves reconstructing randomly masked patches of retinal images while predicting masked text tokens conditioned on the corresponding retinal image. This approach aligns multimodal images and textual expert annotations within a unified latent space, facilitating generalizable and domain-specific representation learning. Experimental results demonstrate that UrFound exhibits strong generalization ability and data efficiency when adapting to various tasks in retinal image analysis. By training on ~180k retinal images, UrFound significantly outperforms the state-of-the-art retinal foundation model trained on up to 1.6 million unlabelled images across 8 public retinal datasets. Our code and data are available at https://github.com/yukkai/UrFound.

  • 8 authors
·
Aug 10, 2024