Health Or Medicine GPT-OSS Model (30 Experts)

Project: https://amanpriyanshu.github.io/GPT-OSS-MoE-ExpertFingerprinting/

👥 Follow the Authors

Aman Priyanshu LinkedIn Twitter Website

Supriti Vijay LinkedIn Twitter Website

Introduction

This is a pruned variant of OpenAI's GPT-OSS-20B model, reduced to 30 experts per layer based on activation patterns from the AmanPriyanshu/GPT-OSS-20B MoE Expert Activations dataset. We analyzed router decisions across evaluation benchmarks to identify and retain experts most relevant for health or medicine tasks.

⚠️ Experimental Model: This is an experimental pruned model that may not work well - check the examples below to see if the outputs meet your needs before use.

This pruning approach reduces the model size while attempting to preserve performance on the target domain.

Model Architecture & Statistics

Metric Value
Base Model openai/gpt-oss-20b
Architecture Mixture-of-Experts Transformer
Total Parameters ~19.7B (pruned from 21B)
Original Experts per Layer 32
Pruned Experts per Layer 30
Layers 24
Top-k Routing 4
Context Length 128K tokens
Attention Heads 64 (Query), 8 (Key-Value)
Residual Dimension 2880
Attention Pattern Alternating dense & sliding window (128 tokens)
Positional Encoding RoPE (Rotary Position Embedding)
Normalization RMSNorm
Precision BF16
License Apache 2.0
Specialization Health Or Medicine

Pruning Methodology

What is Expert Pruning?

Mixture-of-Experts models contain multiple specialized sub-networks (experts) per layer. During inference, only a subset of experts are activated for each token. Expert pruning involves:

  1. Analyzing Usage Patterns: Tracking which experts activate most frequently for specific tasks
  2. Removing Underutilized Experts: Discarding experts with low activation rates for the target domain
  3. Preserving Router Functionality: Maintaining the routing mechanism with fewer available experts

Our Approach

  • Data-Driven Selection: Used activation patterns from health or medicine evaluation tasks
  • Systematic Reduction: Reduced from 32 to 30 experts per layer
  • No Retraining: Direct removal without additional training steps

Performance & Applications

Pruning Benefits

  • Smaller Memory Footprint: 93.8% of original expert parameters
  • Reduced Computational Load: Fewer routing decisions during inference
  • Focused Capabilities: Retains experts relevant to health or medicine tasks

Use Cases

  • Speculative Decoding: Draft model for full GPT-OSS-20B
  • Resource-Constrained Deployment: Edge devices, mobile applications
  • Research: Study expert specialization in MoE models
  • Fine-tuning: Smaller base model for domain adaptation

Note: Performance may vary depending on how well the pruned experts match your specific use case.

Motivation & Expert Selection

This medical domain model incorporates experts that activated highly during health and medical tasks from MMLU medical subjects. These experts specialize in clinical knowledge, anatomy, medical procedures, and health-related reasoning.

The expert selection process utilized our comprehensive analysis of router activation patterns across multiple evaluation benchmarks:

  • GPQA: Graduate-level questions in physics, chemistry, biology (Diamond & Expert subsets)
  • MMLU/MMLU-Pro: Comprehensive knowledge across 57+ subjects including science, medicine, law
  • SORRY-Bench: Safety evaluation across harmful content categories
  • Tulu3: Persona-driven instruction following with verifiable constraints
  • Polyglot-or-Not: Multilingual factual completion tasks

By identifying experts that consistently activated for health or medicine tasks, we created this specialized model that maintains domain expertise while significantly reducing computational requirements from 32 to 30 experts per layer.

Dataset & Analysis Foundation

This model is based on analysis from the GPT-OSS-20B MoE Expert Activations dataset available at: 🔗 https://huggingface.co/datasets/AmanPriyanshu/GPT-OSS-20B-MoE-expert-activations

The dataset contains router activation patterns from OpenAI's GPT-OSS-20B model across diverse evaluation benchmarks, enabling the creation of these domain-optimized models through systematic expert pruning.

Pruning Methodology

Our approach involves:

  1. Activation Analysis: Comprehensive evaluation of expert usage patterns across domain-specific tasks
  2. Expert Ranking: Identification of the most frequently activated experts for target domains
  3. Systematic Pruning: Reduction from 32 to 30 experts while preserving router functionality
  4. Quality Validation: Testing to ensure maintained performance on target tasks

This is a direct pruning approach - no additional training was performed. The model inherits all capabilities from the original GPT-OSS-20B with focused expert selection.

Usage

CPU Inference

from transformers import AutoModelForCausalLM, AutoTokenizer
import torch

# Load the specialized model on CPU
model = AutoModelForCausalLM.from_pretrained(
    "AmanPriyanshu/gpt-oss-19.7b-specialized-health_or_medicine-pruned-moe-only-30-experts", 
    torch_dtype=torch.bfloat16, 
    device_map="cpu", 
    trust_remote_code=True
)
tokenizer = AutoTokenizer.from_pretrained("AmanPriyanshu/gpt-oss-19.7b-specialized-health_or_medicine-pruned-moe-only-30-experts")

# Generate with the model
messages = [
    {"role": "user", "content": "What are the main functions of the human heart?"}
]

inputs = tokenizer.apply_chat_template(
    messages, 
    add_generation_prompt=True, 
    return_tensors="pt", 
    return_dict=True,
    reasoning_effort="medium"
)

# Ensure inputs are on the same device as model
inputs = {k: v.to(model.device) for k, v in inputs.items()}

outputs = model.generate(
    **inputs, 
    max_new_tokens=512,
    do_sample=True,
    temperature=0.1,
    top_p=0.9,
    pad_token_id=tokenizer.eos_token_id,
    eos_token_id=tokenizer.eos_token_id
)

# Decode only the generated part
input_length = inputs['input_ids'].shape[1]
response_tokens = outputs[0][input_length:]
response = tokenizer.decode(response_tokens, skip_special_tokens=True)
print(response)

Apple Silicon (MPS) Inference

from transformers import AutoModelForCausalLM, AutoTokenizer
import torch

# Check MPS availability and load model
device = "mps" if torch.backends.mps.is_available() else "cpu"

model = AutoModelForCausalLM.from_pretrained(
    "AmanPriyanshu/gpt-oss-19.7b-specialized-health_or_medicine-pruned-moe-only-30-experts", 
    torch_dtype=torch.float16,  # Better MPS compatibility
    device_map=device, 
    trust_remote_code=True,
    low_cpu_mem_usage=True
)
tokenizer = AutoTokenizer.from_pretrained("AmanPriyanshu/gpt-oss-19.7b-specialized-health_or_medicine-pruned-moe-only-30-experts")

# Generate with the model
messages = [
    {"role": "user", "content": "What are the main functions of the human heart?"}
]

inputs = tokenizer.apply_chat_template(
    messages, 
    add_generation_prompt=True, 
    return_tensors="pt", 
    return_dict=True,
    reasoning_effort="medium"
)

# Move inputs to model device
inputs = {k: v.to(model.device) if isinstance(v, torch.Tensor) else v for k, v in inputs.items()}

# Use torch.no_grad for MPS stability
with torch.no_grad():
    outputs = model.generate(
        **inputs, 
        max_new_tokens=512,
        do_sample=True,
        temperature=0.1,
        top_p=0.9,
        pad_token_id=tokenizer.eos_token_id,
        eos_token_id=tokenizer.eos_token_id,
        use_cache=True
    )

# Decode only the generated part
input_length = inputs['input_ids'].shape[1]
response_tokens = outputs[0][input_length:]
response = tokenizer.decode(response_tokens, skip_special_tokens=True)
print(response)

GPU Inference

For CUDA GPU inference, the models work with minimal modifications from the CPU example above. Simply change:

device_map="auto"  # Will automatically use GPU if available
torch_dtype=torch.bfloat16  # or torch.float16

Model Examples

The following examples demonstrate the model's performance on health or medicine tasks:

Example 1

Question: What are the main functions of the human heart?

Response:

<|channel|>analysis<|message|>Need to answer.<|end|><|start|>assistant<|channel|>final<|message|>The human heart is a muscular pump that performs several essential functions to keep the circulatory system working efficiently. Its main functions can be grouped into three interrelated categories:

| Function | What it does | Why it matters |
|----------|--------------|----------------|
| **Pumping (circulation)** | • Generates rhythmic contractions (systole) that force blood out of the heart.<br>• Relaxation (diastole) allows the chambers to fill with blood. | Keeps blood moving through the body, delivering oxygen, nutrients, and hormones while removing waste products. |
| **Pressure regulation** | • Maintains arterial pressure (systolic) and venous pressure (diastolic) through coordinated contraction and relaxation.<br>• Works with the autonomic nervous system and hormonal signals (e.g., adrenaline, angiotensin II). | Ensures that blood reaches tissues at the right pressure; prevents damage to capillaries and organs. |
| **Blood distribution (circulatory routing)** | • Divides blood into two main circuits:<br>  – **Pulmonary circuit**: de‑oxygenated blood goes to the lungs for gas exchange.<br>  – **Systemic circuit**: oxygenated blood is delivered to the rest of the body.<br>• Uses valves (tricuspid, pulmonary, mitral, aortic) to keep flow unidirectional. | Guarantees that oxygen‑rich blood reaches every cell and that carbon dioxide and metabolic waste are carried back to the lungs and kidneys for elimination. |

### How the heart accomplishes these functions

1. **Electrical conduction system**  
   - **Sinoatrial (SA) node**: “pacemaker” that initiates the heartbeat.  
   - **Atrioventricular (AV) node, Bundle of His, Purkinje fibers**: conduct the impulse to the ventricles, coordinating contraction.

2. **Cardiac muscle (myocardium)**  
   - Contractile fibers generate force; their contraction is powered by ATP from oxygenated blood.

3. **Valves and chambers**  
   - **Right atrium → right ventricle → pulmonary artery → lungs → left atrium → left ventricle → aorta → body**.  
   - Valves prevent back‑flow, ensuring efficient forward movement.

4. **Autonomic regulation**  
   - Sympathetic stimulation increases heart rate and contractility (fight‑or

Example 2

Question: Explain the difference between bacteria and viruses.

Response:

<|channel|>analysis<|message|>Need concise explanation.<|end|><|start|>assistant<|channel|>final<|message|>**Bacteria vs. Viruses – the big differences**

| Feature | Bacteria | Viruses |
|---------|----------|---------|
| **Basic nature** | Living, single‑cell organisms (prokaryotes). | Non‑living particles; need a host cell to replicate. |
| **Size** | ~0.5–5 µm (visible under light microscope). | ~20–300 nm (visible only with electron microscope). |
| **Structure** | Cell wall, cell membrane, cytoplasm, ribosomes, DNA (circular or linear). | Protein coat (capsid) surrounding a nucleic acid core (DNA or RNA). No metabolic machinery. |
| **Reproduction** | Binary fission (self‑replication). | Hijack host cell’s replication machinery to produce new virions. |
| **Metabolism** | Can grow on nutrients, produce energy, respire, etc. | No metabolism; rely entirely on host cell. |
| **Genetic material** | DNA (sometimes plasmids). | DNA or RNA, single or double stranded. |
| **Response to antibiotics** | Many antibiotics target bacterial cell wall, protein synthesis, etc. | Antibiotics are ineffective; antiviral drugs target specific viral enzymes or entry steps. |
| **Disease mechanisms** | Direct damage, toxin production, immune activation. | Direct cell lysis, immune evasion, integration into host genome (retroviruses). |
| **Examples** | *Escherichia coli*, *Staphylococcus aureus*, *Mycobacterium tuberculosis*. | Influenza virus, HIV, SARS‑CoV‑2, HPV. |

**Bottom line:**  
Bacteria are autonomous, living cells that can grow and reproduce on their own, whereas viruses are inert genetic packages that must invade a host cell to replicate. This fundamental difference shapes how we treat infections: antibiotics for bacteria, antivirals or vaccines for viruses.<|return|>

Example 3

Question: What are the symptoms and causes of diabetes?

Response:

<|channel|>analysis<|message|>Need to answer.<|end|><|start|>assistant<|channel|>final<|message|>**Diabetes mellitus** is a group of metabolic disorders characterized by chronic hyperglycemia (high blood sugar). The two most common types are type 1 and type 2, but there are other less common forms (gestational, MODY, etc.). Below is a concise overview of the main symptoms, causes, and some key differences between the types.

---

## 1. Symptoms (Signs)

| Symptom | Typical Onset | Why It Happens |
|---------|---------------|----------------|
| **Polyuria** (frequent urination) | Early | Kidneys excrete excess glucose, pulling water with it. |
| **Polydipsia** (excessive thirst) | Early | Dehydration from fluid loss. |
| **Polyphagia** (increased hunger) | Early | Cells can’t use glucose, so the body signals for more food. |
| **Weight loss** (especially in type 1) | Early | Body breaks down fat and muscle for energy. |
| **Fatigue / Weakness** | Early | Energy production is impaired. |
| **Blurred vision** | Early | Hyperglycemia causes fluid shifts in the lens. |
| **Slow‑healing cuts or infections** | Early‑mid | Poor blood flow and immune function. |
| **Numbness or tingling in extremities** | Mid‑to‑late | Peripheral neuropathy from chronic high glucose. |
| **Skin changes (dry, itchy, fungal infections)** | Mid‑to‑late | Hyperglycemia impairs skin barrier and immune response. |
| **Recurrent urinary tract or genital infections** | Mid‑to‑late | Glucose in urine provides a food source for bacteria/fungi. |
| **Eye problems (retinopathy, cataracts, glaucoma)** | Late | Chronic damage to retinal vessels and lens. |
| **Kidney problems (proteinuria, decreased GFR)** | Late | Glomerular damage from prolonged hyperglycemia. |
| **Cardiovascular disease (angina, heart attack, stroke)** | Late | Accelerated atherosclerosis. |

> **Tip:** In type 1 diabetes, symptoms often appear rapidly (days to weeks). In type 2, they can develop insidiously over months or years, sometimes going unnoticed until complications arise.

---

## 2. Causes & Risk Factors

| Category | Key Points |
|----------|------------|
| **Type

Citation

If you use this model in your research, please cite:

@misc{priyanshu2025gptoss,
  title={{GPT-OSS MoE Expert Fingerprinting: Analyzing Expert Activation Patterns in Mixture of Experts Models}},
  author={Priyanshu, Aman and Vijay, Supriti},
  year={2025},
  howpublished={\url{https://amanpriyanshu.github.io/GPT-OSS-MoE-ExpertFingerprinting/}},
  note={Interactive analysis tool for expert activation patterns in MoE architectures}
}

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