Health Or Medicine GPT-OSS Model (12 Experts)

Project: https://amanpriyanshu.github.io/GPT-OSS-MoE-ExpertFingerprinting/

👥 Follow the Authors

Aman Priyanshu LinkedIn Twitter Website

Supriti Vijay LinkedIn Twitter Website

Introduction

This is a pruned variant of OpenAI's GPT-OSS-20B model, reduced to 12 experts per layer based on activation patterns from the AmanPriyanshu/GPT-OSS-20B MoE Expert Activations dataset. We analyzed router decisions across evaluation benchmarks to identify and retain experts most relevant for health or medicine tasks.

⚠️ Experimental Model: This is an experimental pruned model that may not work well - check the examples below to see if the outputs meet your needs before use.

This pruning approach reduces the model size while attempting to preserve performance on the target domain.

Model Architecture & Statistics

Metric Value
Base Model openai/gpt-oss-20b
Architecture Mixture-of-Experts Transformer
Total Parameters ~9.0B (pruned from 21B)
Original Experts per Layer 32
Pruned Experts per Layer 12
Layers 24
Top-k Routing 4
Context Length 128K tokens
Attention Heads 64 (Query), 8 (Key-Value)
Residual Dimension 2880
Attention Pattern Alternating dense & sliding window (128 tokens)
Positional Encoding RoPE (Rotary Position Embedding)
Normalization RMSNorm
Precision BF16
License Apache 2.0
Specialization Health Or Medicine

Pruning Methodology

What is Expert Pruning?

Mixture-of-Experts models contain multiple specialized sub-networks (experts) per layer. During inference, only a subset of experts are activated for each token. Expert pruning involves:

  1. Analyzing Usage Patterns: Tracking which experts activate most frequently for specific tasks
  2. Removing Underutilized Experts: Discarding experts with low activation rates for the target domain
  3. Preserving Router Functionality: Maintaining the routing mechanism with fewer available experts

Our Approach

  • Data-Driven Selection: Used activation patterns from health or medicine evaluation tasks
  • Systematic Reduction: Reduced from 32 to 12 experts per layer
  • No Retraining: Direct removal without additional training steps

Performance & Applications

Pruning Benefits

  • Smaller Memory Footprint: 37.5% of original expert parameters
  • Reduced Computational Load: Fewer routing decisions during inference
  • Focused Capabilities: Retains experts relevant to health or medicine tasks

Use Cases

  • Speculative Decoding: Draft model for full GPT-OSS-20B
  • Resource-Constrained Deployment: Edge devices, mobile applications
  • Research: Study expert specialization in MoE models
  • Fine-tuning: Smaller base model for domain adaptation

Note: Performance may vary depending on how well the pruned experts match your specific use case.

Motivation & Expert Selection

This medical domain model incorporates experts that activated highly during health and medical tasks from MMLU medical subjects. These experts specialize in clinical knowledge, anatomy, medical procedures, and health-related reasoning.

The expert selection process utilized our comprehensive analysis of router activation patterns across multiple evaluation benchmarks:

  • GPQA: Graduate-level questions in physics, chemistry, biology (Diamond & Expert subsets)
  • MMLU/MMLU-Pro: Comprehensive knowledge across 57+ subjects including science, medicine, law
  • SORRY-Bench: Safety evaluation across harmful content categories
  • Tulu3: Persona-driven instruction following with verifiable constraints
  • Polyglot-or-Not: Multilingual factual completion tasks

By identifying experts that consistently activated for health or medicine tasks, we created this specialized model that maintains domain expertise while significantly reducing computational requirements from 32 to 12 experts per layer.

Dataset & Analysis Foundation

This model is based on analysis from the GPT-OSS-20B MoE Expert Activations dataset available at: 🔗 https://huggingface.co/datasets/AmanPriyanshu/GPT-OSS-20B-MoE-expert-activations

The dataset contains router activation patterns from OpenAI's GPT-OSS-20B model across diverse evaluation benchmarks, enabling the creation of these domain-optimized models through systematic expert pruning.

Pruning Methodology

Our approach involves:

  1. Activation Analysis: Comprehensive evaluation of expert usage patterns across domain-specific tasks
  2. Expert Ranking: Identification of the most frequently activated experts for target domains
  3. Systematic Pruning: Reduction from 32 to 12 experts while preserving router functionality
  4. Quality Validation: Testing to ensure maintained performance on target tasks

This is a direct pruning approach - no additional training was performed. The model inherits all capabilities from the original GPT-OSS-20B with focused expert selection.

Usage

CPU Inference

from transformers import AutoModelForCausalLM, AutoTokenizer
import torch

# Load the specialized model on CPU
model = AutoModelForCausalLM.from_pretrained(
    "AmanPriyanshu/gpt-oss-9.0b-specialized-health_or_medicine-pruned-moe-only-12-experts", 
    torch_dtype=torch.bfloat16, 
    device_map="cpu", 
    trust_remote_code=True
)
tokenizer = AutoTokenizer.from_pretrained("AmanPriyanshu/gpt-oss-9.0b-specialized-health_or_medicine-pruned-moe-only-12-experts")

# Generate with the model
messages = [
    {"role": "user", "content": "What are the main functions of the human heart?"}
]

inputs = tokenizer.apply_chat_template(
    messages, 
    add_generation_prompt=True, 
    return_tensors="pt", 
    return_dict=True,
    reasoning_effort="medium"
)

# Ensure inputs are on the same device as model
inputs = {k: v.to(model.device) for k, v in inputs.items()}

outputs = model.generate(
    **inputs, 
    max_new_tokens=512,
    do_sample=True,
    temperature=0.1,
    top_p=0.9,
    pad_token_id=tokenizer.eos_token_id,
    eos_token_id=tokenizer.eos_token_id
)

# Decode only the generated part
input_length = inputs['input_ids'].shape[1]
response_tokens = outputs[0][input_length:]
response = tokenizer.decode(response_tokens, skip_special_tokens=True)
print(response)

Apple Silicon (MPS) Inference

from transformers import AutoModelForCausalLM, AutoTokenizer
import torch

# Check MPS availability and load model
device = "mps" if torch.backends.mps.is_available() else "cpu"

model = AutoModelForCausalLM.from_pretrained(
    "AmanPriyanshu/gpt-oss-9.0b-specialized-health_or_medicine-pruned-moe-only-12-experts", 
    torch_dtype=torch.float16,  # Better MPS compatibility
    device_map=device, 
    trust_remote_code=True,
    low_cpu_mem_usage=True
)
tokenizer = AutoTokenizer.from_pretrained("AmanPriyanshu/gpt-oss-9.0b-specialized-health_or_medicine-pruned-moe-only-12-experts")

# Generate with the model
messages = [
    {"role": "user", "content": "What are the main functions of the human heart?"}
]

inputs = tokenizer.apply_chat_template(
    messages, 
    add_generation_prompt=True, 
    return_tensors="pt", 
    return_dict=True,
    reasoning_effort="medium"
)

# Move inputs to model device
inputs = {k: v.to(model.device) if isinstance(v, torch.Tensor) else v for k, v in inputs.items()}

# Use torch.no_grad for MPS stability
with torch.no_grad():
    outputs = model.generate(
        **inputs, 
        max_new_tokens=512,
        do_sample=True,
        temperature=0.1,
        top_p=0.9,
        pad_token_id=tokenizer.eos_token_id,
        eos_token_id=tokenizer.eos_token_id,
        use_cache=True
    )

# Decode only the generated part
input_length = inputs['input_ids'].shape[1]
response_tokens = outputs[0][input_length:]
response = tokenizer.decode(response_tokens, skip_special_tokens=True)
print(response)

GPU Inference

For CUDA GPU inference, the models work with minimal modifications from the CPU example above. Simply change:

device_map="auto"  # Will automatically use GPU if available
torch_dtype=torch.bfloat16  # or torch.float16

Model Examples

The following examples demonstrate the model's performance on health or medicine tasks:

Example 1

Question: What are the main functions of the human heart?

Response:

<|channel|>analysis<|message|>Need to answer: main functions of heart: pumping blood, regulating blood pressure, oxygen delivery, endocrine functions (h hormones), electrical conduction, etc.<|end|><|start|>assistant<|channel|>final<|message|>**The human heart is a vital organ that performs several key functions essential for life. These functions can be grouped into three main categories:**

---

### 1. **Circulatory (P pumping) Functions**

| Function | What it Does | Why It Matters |
|----------|--------------|--------------|
| **Pens the blood** – The heart’s chambers (right‑side: right atrium → right ventricle; left‑side: left atrium → left ventricle) contract in a coordinated rhythm to push blood through the circulatory system. | Keeps oxygen and nutrients delivered to every tissue and organ. |
| **Regulates blood pressure** – By adjusting the force of contraction (stroke volume) and the rate of heartbeats (heart rate), the heart maintains a constant blood pressure. | Keeps blood flow steady, preventing both low‑pressure (hypotension) and high‑pressure (hypertension) conditions. |
| **Controls blood flow direction** – The heart’s valves (mitral, trmitral, aortic, pulmonary, etc.) ensure that blood moves in the right direction and does not leak back into the chambers. | Prevents back‑flow and preserves efficient circulation. |

---

### 2. **Electrical Conduction (Rhythm) Functions**

| Function | What it Does | Why It Matters |
|----------|--------------|--------------|
| **Generates an electrical impulse** – The sino‑aurial (SA) node initiates the heartbeat. | Sets the rhythm that the heart follows. |
| **Relates the impulse to the heart muscle** – The atr‑ventricular (AV) node and the bundle of His transmit the impulse from the atria to the ventricles. | Allows the atria and ventricles to contract in a coordinated sequence. |
| **Propensens the impulse to the ventricles** – The Purus‑van‑Allen bundle (bundle of right/left) ensures the ventricles contract in synchrony. | Guarantees a coordinated, efficient pumping action. |

---

### 3. **End‑Organ (Hormetic) Functions**

| Function | What it Does | Why It Matters |
|----------|--------------|--------------|
| **Sese hormones** – The heart releases substances such as **angi‑inogen** (promes new blood‑

Example 2

Question: Explain the difference between bacteria and viruses.

Response:

<|channel|>analysis<|message|>Need explain differences: size, structure, replication, genetics, disease, treatment.<|end|><|start|>assistant<|channel|>final<|message|>**Bacteria vs. Virons – the “Micro‑Life” Showdown**

| Feature | Bacteria | Virons |
|--------- |----------- |----------- |
| **What they are** | Single‑cell, living organisms (pro‑ or e‑) that can grow and divide on their own. | Tiny particles that are not living cells; they are made of a small piece of genetic material (DNA or RNA) plus a protein shell. |
| **Size** | 1 – 10 µm (visible under a microscope). | 100 – 200 nm (usually invisible to light‑microscopy). |
| **Structure** | A cell with a membrane, ribosomes, DNA, and many organelles (e.g., mitochond‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑‑

Example 3

Question: What are the symptoms and causes of diabetes?

Response:

<|channel|>analysis<|message|>Need to give overview.<|end|><|start|>assistant<|channel|>final<|message|>**Diabetes mellitus** is a chronic metabolic disorder in which the body cannot produce or use insulin effectively, leading to high blood glucose (hyper‑gly) levels.  The two main types are:

| Type | Pathophysiology | Typical onset | Key clinical features |
|------|-------------------|----------------|------------------------|
| Type 1 | Autoimmune destruction of β‑isβ‑cells → absolute insulin deficiency | Usually in 2–3 years of childhood, but can occur at any age | • Rapid onset of hyper‑gly; • Weight loss; • Poly‑urho; • Fatigue; • Re‑current infections (UTIs, thrung, skin) |
| Type 2 | Ins insulin resistance → relative insulin deficiency (often secondary) | Usually 10–20 years of adulthood; ↑ with obesity, inactivity, genetics | • Gradual hyper‑gly; • Weight gain; • Fatigue; • Peripheral neuropathy; • Retinopathy; • Cardi‑vascular risk |

---

## Symptoms (common across both types)

| Symptom | Why it occurs | Typical presentation |
|--------|----------------|------------------------|
| **Poly‑urho** | Kidneys ex‑glucose → water → urine | “Frequent” or “un‑controlled” ur‑frequency, especially in the 2–3 th decade |
| **Polod** | Osmos‑pressure ↑ → thirst | “Constant thirst” or “dring” for water/juice |
| **Weight loss** (Type 1) / **Weight gain** (Type 2) | Metabolic shift & insulin deficiency | Rapid weight loss in Type 1; gradual weight gain in Type 2 |
| **Fatigue / Mala** | Hyper‑gly & metabolic stress | “Feeling tired” or “weak” for days |
| **Infections** | Hyper‑gly imp‑immune | Re‑current UTIs, thrung, skin infections |
| **Neuropathy** | Chronic hyper‑gly → nerve damage | Tingting, numbness, pain in extremities |
| **Retinopathy** | Chronic hyper‑gly → micro‑vascular damage | Vision changes, floaters, blurred vision |
| **Foot ulcers** | Peripheral neuropathy + poor circulation | Painful, non‑healing wounds on toes/feet |
| **Cardi‑vascular symptoms** | Hyper‑gly + dyslip → atheros

Citation

If you use this model in your research, please cite:

@misc{priyanshu2025gptoss,
  title={{GPT-OSS MoE Expert Fingerprinting: Analyzing Expert Activation Patterns in Mixture of Experts Models}},
  author={Priyanshu, Aman and Vijay, Supriti},
  year={2025},
  howpublished={\url{https://amanpriyanshu.github.io/GPT-OSS-MoE-ExpertFingerprinting/}},
  note={Interactive analysis tool for expert activation patterns in MoE architectures}
}

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