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counts
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[1,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0(...TRUNCATED) | [2.915452003479004,0.0,0.0,0.0,0.0,0.0,0.0,0.0,2.915452003479004,0.0,0.0,0.0,0.0,0.0,2.9154520034790(...TRUNCATED) | [0.6931471824645996,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.6931471824645996,0.0,0.0,0.0,0.0,0.0,0.69314718246(...TRUNCATED) | [1.3649307489395142,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.3649307489395142,0.0,0.0,0.0,0.0,0.0,1.36493074893(...TRUNCATED) | ["TSPAN6","TNMD","DPM1","SCYL3","C1orf112","FGR","CFH","FUCA2","GCLC","NFYA","STPG1","NIPAL3","LAS1L(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.7191551327705383,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.537960350513458(...TRUNCATED) | [2.6346070766448975,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.537960350513458(...TRUNCATED) | [0.41230228543281555,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.53796035051345(...TRUNCATED) | [1.0840858221054077,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.537960350513458(...TRUNCATED) | A549 | Nutlin | 0.5 | µM | COc1ccc(C2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N2C(=O)N2CCNC(=O)C2)c(OC(C)C)c1 | MDM2 inhibitor | p53-MDM2 interaction antagonist | Stabilizes p53 → induces cell cycle arrest and apoptosis in cancer cells | AB02 | 24h | " This is a cell from cell line: A549. It was given drug: **Nutlin** at dosage 0.5 µM at timepoint:(...TRUNCATED) | [-0.0026579892728477716,-0.007448068354278803,0.03556770458817482,0.03107561357319355,-0.03365965560(...TRUNCATED) | [0.5645167827606201,-0.7891343235969543,-0.23261886835098267,-0.3651169538497925,-0.2509405910968780(...TRUNCATED) |
[0,0,1,0,0,0,1,2,4,0,0,0,0,0,0,0,2,0,1,0,0,0,0,0,0,0,0,0,2,1,0,0,0,0,0,0,1,0,0,0,0,2,0,1,0,0,0,0,0,0(...TRUNCATED) | [0.0,0.0,1.5356265306472778,0.0,0.0,0.0,1.5356265306472778,3.0712530612945557,6.142506122589111,0.0,(...TRUNCATED) | [0.0,0.0,0.6931471824645996,0.0,0.0,0.0,0.6931471824645996,1.0986123085021973,1.6094379425048828,0.0(...TRUNCATED) | [0.0,0.0,0.9304407835006714,0.0,0.0,0.0,0.9304407835006714,1.403950810432434,1.9660637378692627,0.0,(...TRUNCATED) | ["TSPAN6","TNMD","DPM1","SCYL3","C1orf112","FGR","CFH","FUCA2","GCLC","NFYA","STPG1","NIPAL3","LAS1L(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,0.1499006301164627,-0.3172188103199005,-0.53796035051345(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,0.6855271458625793,-0.3172188103199005,-0.53796035051345(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.15695218741893768,-0.3172188103199005,-0.537960350513(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,0.0803413912653923,-0.3172188103199005,-0.53796035051345(...TRUNCATED) | A549 | Dex | 50 | µM | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO | Corticosteroid | Glucocorticoid receptor agonist | Modulates transcription of anti-inflammatory and metabolic genes | BC10 | 24h | " This is a cell from cell line: A549. It was given drug: **Dex** at dosage 50 µM at timepoint: 24h(...TRUNCATED) | [-0.012991716153919697,-0.004959221929311752,0.024141862988471985,0.026553111150860786,-0.0404994711(...TRUNCATED) | [0.021047716960310936,0.06128780171275139,-0.4593315124511719,0.8392474055290222,-0.0542722307145595(...TRUNCATED) |
[0,0,0,0,1,0,3,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,3,0,0,0,0,0,0,0,0,0,0,1,0,5,0,0,0,1,0,0,0,1(...TRUNCATED) | [0.0,0.0,0.0,0.0,1.8677624464035034,0.0,5.603287220001221,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.8677(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.6931471824645996,0.0,1.3862943649291992,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.693(...TRUNCATED) | [0.0,0.0,0.0,0.0,1.0535321235656738,0.0,1.8875676393508911,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.053(...TRUNCATED) | ["TSPAN6","TNMD","DPM1","SCYL3","C1orf112","FGR","CFH","FUCA2","GCLC","NFYA","STPG1","NIPAL3","LAS1L(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,0.46203967928886(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,1.32980203628540(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,0.15518684685230(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,0.51557177305221(...TRUNCATED) | A549 | BMS | 0.5 | µM | Cc1ccc2nc(NCCN)c3ncc(C)n3c2c1 | NF-κB pathway inhibitor | IκB kinase-β inhibitor | Blocks NF-κB signaling → suppresses inflammatory and survival-related gene expression | AH10 | 24h | " This is a cell from cell line: A549. It was given drug: **BMS** at dosage 0.5 µM at timepoint: 24(...TRUNCATED) | [-0.024514291435480118,0.006129854824393988,0.013937752693891525,0.02957836166024208,-0.007973769679(...TRUNCATED) | [-0.13988883793354034,-0.674958348274231,-0.0003305375576019287,0.07370085269212723,-0.2732155025005(...TRUNCATED) |
[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,1,0,0(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,3.1476235389709473,3.1476235389709473,0(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.6931471824645996,0.6931471824645996,0(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.4225355386734009,1.4225355386734009,0(...TRUNCATED) | ["TSPAN6","TNMD","DPM1","SCYL3","C1orf112","FGR","CFH","FUCA2","GCLC","NFYA","STPG1","NIPAL3","LAS1L(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | A549 | Nutlin | 0 | µM | COc1ccc(C2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N2C(=O)N2CCNC(=O)C2)c(OC(C)C)c1 | MDM2 inhibitor | p53-MDM2 interaction antagonist | Stabilizes p53 → induces cell cycle arrest and apoptosis in cancer cells | AB04 | 24h | " This is a cell from cell line: A549. It was given drug: **Nutlin** at dosage 0 µM at timepoint: 2(...TRUNCATED) | [-0.004334749188274145,-0.008085495792329311,0.035460229963064194,0.02853611297905445,-0.03315310180(...TRUNCATED) | [0.5645167827606201,-0.7891343235969543,-0.23261886835098267,-0.3651169538497925,-0.2509405910968780(...TRUNCATED) |
[0,0,0,0,0,0,0,0,6,0,0,0,0,0,0,0,1,0,1,0,0,0,1,0,0,0,0,0,1,0,3,0,0,0,0,0,0,0,0,0,2,1,0,1,0,0,0,0,0,0(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,11.804052352905273,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.9673421382904053,0(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.945910096168518,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.6931471824645996,0.(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,2.5497617721557617,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.087666630744934,0.(...TRUNCATED) | ["TSPAN6","TNMD","DPM1","SCYL3","C1orf112","FGR","CFH","FUCA2","GCLC","NFYA","STPG1","NIPAL3","LAS1L(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | A549 | BMS | 0.1 | µM | Cc1ccc2nc(NCCN)c3ncc(C)n3c2c1 | NF-κB pathway inhibitor | IκB kinase-β inhibitor | Blocks NF-κB signaling → suppresses inflammatory and survival-related gene expression | BH11 | 24h | " This is a cell from cell line: A549. It was given drug: **BMS** at dosage 0.1 µM at timepoint: 24(...TRUNCATED) | [-0.024588000029325485,0.006490749306976795,0.012422050349414349,0.028989147394895554,-0.00804704707(...TRUNCATED) | [-0.13988883793354034,-0.674958348274231,-0.0003305375576019287,0.07370085269212723,-0.2732155025005(...TRUNCATED) |
[0,0,0,0,0,0,1,1,8,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,2,3,0,0,2,0,0,1,1,2,0,1,4,0,0,0,0,0,0,0,1(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.7213966250419617,0.7213966250419617,5.771173000335693,0.0,0.0,0.0,0.0,0.0(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.6931471824645996,0.6931471824645996,2.1972246170043945,0.0,0.0,0.0,0.0,0.(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.543135941028595,0.543135941028595,1.9126743078231812,0.0,0.0,0.0,0.0,0.0,(...TRUNCATED) | ["TSPAN6","TNMD","DPM1","SCYL3","C1orf112","FGR","CFH","FUCA2","GCLC","NFYA","STPG1","NIPAL3","LAS1L(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | A549 | Nutlin | 10 | µM | COc1ccc(C2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N2C(=O)N2CCNC(=O)C2)c(OC(C)C)c1 | MDM2 inhibitor | p53-MDM2 interaction antagonist | Stabilizes p53 → induces cell cycle arrest and apoptosis in cancer cells | AA03 | 24h | " This is a cell from cell line: A549. It was given drug: **Nutlin** at dosage 10 µM at timepoint: (...TRUNCATED) | [-0.0029703150503337383,-0.006225402466952801,0.03416445106267929,0.030518025159835815,-0.0315064564(...TRUNCATED) | [0.5645167827606201,-0.7891343235969543,-0.23261886835098267,-0.3651169538497925,-0.2509405910968780(...TRUNCATED) |
[0,0,0,0,0,0,0,0,1,0,0,0,1,2,0,0,1,0,0,0,0,0,1,0,0,0,0,0,2,0,1,0,0,1,0,0,2,0,0,0,0,1,1,0,0,0,0,0,3,0(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.7806267738342285,0.0,0.0,0.0,1.7806267738342285,3.561253547668457(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.6931471824645996,0.0,0.0,0.0,0.6931471824645996,1.098612308502197(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.0226763486862183,0.0,0.0,0.0,1.0226763486862183,1.517597436904907(...TRUNCATED) | ["TSPAN6","TNMD","DPM1","SCYL3","C1orf112","FGR","CFH","FUCA2","GCLC","NFYA","STPG1","NIPAL3","LAS1L(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | A549 | SAHA | 0.5 | µM | O=C(CCCCCCC(=O)Nc1ccccc1)NO | Epigenetic modulator | Histone deacetylase 1 inhibitor | Reactivates silenced genes → induces apoptosis and cell differentiation | AF02 | 24h | " This is a cell from cell line: A549. It was given drug: **SAHA** at dosage 0.5 µM at timepoint: 2(...TRUNCATED) | [-0.030821390450000763,0.005353412125259638,0.02100495807826519,0.009830552153289318,-0.016747286543(...TRUNCATED) | [0.49903419613838196,-0.2588857114315033,-0.5308424830436707,-0.052395522594451904,-0.51525020599365(...TRUNCATED) |
[0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,3,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,5.714285850524902,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,17.14285659790039,0.0(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,0.6931471824645996,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,1.3862943649291992,0(...TRUNCATED) | [0.0,0.0,0.0,0.0,0.0,0.0,1.9042375087738037,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,0.0,2.8982770442962646,0(...TRUNCATED) | ["TSPAN6","TNMD","DPM1","SCYL3","C1orf112","FGR","CFH","FUCA2","GCLC","NFYA","STPG1","NIPAL3","LAS1L(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [0.28084489703178406,0.019348887726664543,0.8500993847846985,0.3172188103199005,0.5379603505134583,0(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | [-0.28084489703178406,-0.019348887726664543,-0.8500993847846985,-0.3172188103199005,-0.5379603505134(...TRUNCATED) | A549 | Dex | 0.5 | µM | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO | Corticosteroid | Glucocorticoid receptor agonist | Modulates transcription of anti-inflammatory and metabolic genes | BD10 | 24h | " This is a cell from cell line: A549. It was given drug: **Dex** at dosage 0.5 µM at timepoint: 24(...TRUNCATED) | [-0.014536228962242603,-0.004569827578961849,0.025828521698713303,0.027566365897655487,-0.0383896231(...TRUNCATED) | [0.021047716960310936,0.06128780171275139,-0.4593315124511719,0.8392474055290222,-0.0542722307145595(...TRUNCATED) |
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Dataset Description
A549 Chemical Perturbation Dataset (SciPlex2)
This dataset captures transcriptional responses of A549, a human lung adenocarcinoma cell line, to drug perturbations. Cells were treated with one of four small molecules:
- Dexamethasone, corticosteroid receptor agonist
- Nutlin-3a, p53-MDM2 interaction antagonist
- BMS-345541, inhibitor of NF-κB–dependent transcription
- Vorinostat (SAHA), histone deacetylase (HDAC) inhibitor
Each compound was applied for 24 hours across seven doses, in triplicate, resulting in 84 compound–dose–replicate conditions, along with additional vehicle controls. Single-cell transcriptional profiles were generated using sci-RNA-seq.
Additional Information
- Normalized counts were scaled so that the total expression per cell sums to
1e4. - Control counts represent the average expression of each gene across all control cells.
- Delta values are computed as the difference between each sample's expression and the corresponding control mean.
- SMILES strings and mechanism of action (MoA) annotations were retrieved from the ChEMBL database and enhanced with additional sources.
Citation
Srivatsan, S. R., McFaline-Figueroa, J. L., Ramani, V. et al.
Massively multiplex chemical transcriptomics at single-cell resolution
Science, 367, 45–51 (2020).
https://doi.org/10.1126/science.aax6234
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