id
int64 | text
string | fineweb2hq
float64 | finewebedu
float64 | gneiss
float64 | nemo
float64 | nvidia
float64 | ultrafineweb
float64 | uvp
float64 | score
float64 |
|---|---|---|---|---|---|---|---|---|---|
3,976 |
Background A complete remission is essential for prolongingsurvival in patients with acute myeloid leukemia (AML). Daunorubicinis a cornerstone of the induction regimen, but the optimal doseis unknown. In older patients, it is usual to give daunorubicinat a dose of 45 to 50 mg per square meter of body-surface area.
Methods Patients in whom AML or high-risk refractory anemiahad been newly diagnosed and who were 60 to 83 years of age(median, 67) were randomly assigned to receive cytarabine, ata dose of 200 mg per square meter by continuous infusion for7 days, plus daunorubicin for 3 days, either at the conventionaldose of 45 mg per square meter (411 patients) or at an escalateddose of 90 mg per square meter (402 patients); this treatmentwas followed by a second cycle of cytarabine at a dose of 1000mg per square meter for 6 days. The primary end point was event-freesurvival.
Results The complete remission rates were 64% in the group thatreceived the escalated dose of daunorubicin and 54% in the groupthat received the conventional dose (P=0.002); the rates ofremission after the first cycle of induction treatment were52% and 35%, respectively (P<0.001). There was no significantdifference between the two groups in the incidence of hematologictoxic effects, 30-day mortality (11% and 12% in the two groups,respectively), or the incidence of moderate, severe, or life-threateningadverse events (P=0.08). Survival end points in the two groupsdid not differ significantly overall, but patients in the escalated-treatmentgroup who were 60 to 65 years of age, as compared with the patientsin the same age group who received the conventional dose, hadhigher rates of complete remission (73% vs. 51%), event-freesurvival (29% vs. 14%), and overall survival (38% vs. 23%).
From Erasmus University Medical Center, Rotterdam (B.L., P.S., M.J.-L.); the Department of Hematology, Free University Medical Center, Amsterdam (G.J.O.); the HOVON Data Center and Department of Trials and Statistics, Erasmus University Medical Center, Rotterdam (W.P.); University Medical Center, Maastricht (H.C.S.); Amsterdam University Medical Center, Amsterdam (B.J.B.); University Medical Center, Groningen (E.V.); Isala Hospital, Zwolle (M.M.K.); and University Medical Center, Utrecht (L.F.V.) — all in the Netherlands; Hôpital Mont Godinne, Yvoir (C.G.); Hôpital St. Luc, Brussels (A.F.); and University Hospital Gasthuisberg, Leuven (J.M., G.V.) — all in Belgium; University Hospital, Bonn (M.L.-T.); the Department of Internal Medicine III, University-Hospital, Mainz (J.B.); and the Department of Internal Medicine III, University of Ulm, Ulm (H.D.) — all in Germany; and University Hospital, Basel (A.G.); and Inselspital, Bern (T.P.) — both in Switzerland.
| 4.766824 | 1.513372 | -5.563197 | 0.69799 | 4.679982 | -1.257013 | 3.31663 | 0.742069 |
97,091 |
Click the button below to add the Teapot Ceramic Rabbit to your wish list.
Hand painted raised ceramic rabbit shape teapot.
10 1/4" H X 1 1/4" Opening. Holds 20 oz.
| -6.523993 | 0.059027 | -11.510315 | 0.127902 | 1.378101 | -11.135096 | -4.758792 | -1.686303 |
80,475 |
The challenges we face are large, complex, and ambiguous. The way to solve these challenges and create our desired impact is together.
My workshops bring people together. They are human-centered through and through, and provide a caring, fun and hands-on experience that gets results.
"As a newly formed team, I wanted to bring everyone together for the first time to build a strong foundation. Alla put together an outstanding agenda to build rapport, establish norms and helped us understand our values to develop a cohesive identity. I would recommend Alla to facilitate team activities, helping new teams form and designing a foundation for a team to succeed."
"Over the past few months, I have been lucky enough to participate in several workshops facilitated by Alla. Each time, I learn something about facilitation, about myself, and about my colleagues and our work. She has an uncanny ability to read the room and bring people together on a journey to the group's desired outcomes. I would highly recommend Alla if your team needs direction, motivation, alignment, vision, or tension relief. Her true passion is to help teams connect and find their purpose - and it shows through in everything that she does."
| 4.753891 | 0.886943 | -0.827863 | 0.992825 | 5.011144 | -1.62125 | 1.005018 | 0.770448 |
15,715 |
5 metre 125 micron singlemode fibre optic cable terminated with SC connectors at both ends, for use as a patch lead in networks employing optical fibre cable infrastructure. The cable has yellow sheathing.
5 metre singlemode fibre optic cable. 125 micrometre core diameter. Terminated with SC connectors at both ends. Yellow sheathing. Can be used in all grades of Ethernet networks (10Mbps to 100Gigabit) and a variety of other systems including EPON and GPON passive optical networks, Fibre channel, HIPPI, OTN and ATM (SDH or SONET).
| 4.767398 | 0.883767 | -7.450097 | 1.376186 | -0.583461 | -2.829542 | -1.829292 | 0.085472 |
96,524 |
Airbus is no stranger to unusual designs. In 2014, the budget travel giant registered a patent for a flying saucer, with circular seating arrangements that expanded outward from the center of the plane.
But for every loony design that becomes an Airbus intellectual property, there’s hundreds of stark raving insane concepts that never make it past the drawing board. Every year, hundreds of potential new patents aren’t up to snuff, and they’re scrapped until the next round of brain storming and market research begins.
National Report has it on good authority that the following images are official unused Airbus designs left on the cutting room floor. These schematics were relinquished to me by a shrewd, entrepreneurial-minded Airbus janitor who rescued them from their fateful meeting with a paper shredder.
The Sky Chariot can hold up to 500 passengers, who are then laid side to side on comfortable hammocks for the entire length of the massive plane. It’s believed that flying across country on The Sky Chariot would only cost customers $20.00 American, had it made the cut.
In the instance that you find yourself feeling anti-social, consider The Iron Maiden, which is a medievil torture device fitted with a plane engine and wings. Several blades are strategically welded into the single passenger seating area which then punctures major organs upon closing of the pod doors.
Or if you’re of the religious persuasion, the Cruci-Flier is a flight custom made for your sensibilities. You and two other lucky passengers are nailed to wooden crosses before being rocketed to your final destination.
Going to a tropical hot-spot? Why not get your sultry dream vacation started early with Airbus original: The Erupting Volcano. You will be directly in the midst of a destructive volcano, viciously erupting for the entire duration of your trip. Can’t get much more exciting than that!
The Guantanamo Bay Detention Center modified for air travel. If comfort isn’t a big concern, this plane is sure to cushion your wallet–just not your hind-end! Flight attendants patrol the aircraft with vicious attack dogs and take mocking photographs of your naked body smeared in feces. With The Guantanamo Bay model you can experience water boarding, extended solitary confinement and even sensory deprivation miles above the ground!
Because Airbus wanted make full use of the clip-art they had purchased, I present to you The Dynamo Package. The Dynamo Package was designed so that you could experience both the agony of Crucifixion, while also enduring torrents of ash and scalding lava. Truly there is no finer way to travel.
We presented the Airbus drafts to several people awaiting flights at the Portland International Airport, asking if they would consider traveling under these various conditions. The reviews were decidedly split.
Tim Mercer, an Oregon native, rarely flies, but when he does it’s cross country to see his grandparents in Daytona Beach Florida. Annoyed with the abundance of fellow passengers, Mercer noted that the Iron Maiden looked particularly comfortable, and that he would definitely consider the benefits of flying solo if given the option.
| 4.762934 | 1.598082 | -2.916493 | 1.411124 | 2.182164 | -1.074979 | -1.774343 | 0.774713 |
91,307 |
I first started building electrical and electronic circuits from about the age of 7. I started building all sorts of interesting circuits with Electronic kits using the supplied instruction manuals. I quickly graduated to taking broken electronic items apart to see how they work, this also provided me with a vast array of switches, components and meters I could use in my own projects. I was always heading in to town to buy components or those really interesting Babani books full of Electronics circuit ideas and projects. I also bought Everyday Electronics magazine and marvelled at the circuits that I could afford to build, and the ones that were too big or which were out of my price range, but it was still interesting to see how they worked.
I was entirely self taught in electronics until I was 14, when I attended a set of after school ‘Build a Radio’ classes run by a teacher at Evesham High School in the 70’s. In these after school classes we built our own working radios from discrete components. Later I supplemented my knowledge by attended a TV and Radio Repair night school class. This helped me to make money by repairing televisions for neighbours, and repairing CB’s for the local CB Radio enthusiasts (of which I was one). Although I had served my apprenticeship as a motor mechanic and HGV Fitter, it now looked like my career would be in electronics…. until I bought my first computer.
I had my first brush with programming at school in the 1970’s when I attended an after school course in programming an electrical/mechanical calculator/machine/device, I am not sure what the machine was but I still have a printout from the device. This printout (which is about an inch wide) was the program I wrote to calculate the distance travelled by a falling object under the influence of gravity. Following this I became a HGV fitter and spent every Monday away from my work in a garage on day release, studying for my Motor Vehicle apprenticeship in a local technical college. I discovered the college had a mainframe computer, so I would spend my dinner time in the computer room, using the terminals connected to the mainframe, there were no monitors at that time, the output was on to rolls of paper.
I got my first computer when I bought a ZX81 on 7th November 1982 and played the breakout game I bought with it, I then read the manual that came with the computer and was hooked, I taught myself programming from the ZX81 manual. I did not know of anyone in the area who even owned a computer or knew what they could do, so I had nobody to discuss computers with, they were a bit of a specialist subject back then. I started working flat out learning how to write software I then graduated to the Sinclair Spectrum, and then to the Sinclair QL.
In 1985 I went in to WH Smiths in Preston and saw a typing tutor for sale for £29.95. I told the shop assistant who I regularly chatted to, that the software was over priced and that I could write something better myself, he challenged me, and I set about writing Touch Typist to prove my claim.
Two weeks later, after working flat out, I took a program in to show him and he was amazed that it was better than the one he was selling, he said that I should market it. I then set about writing new features and expanding the software until it was ready for sale.
I managed to get an Enterprise Allowance grant of £40 per week for one year to start up self employed, writing software. I started my business from home in October 1985, later on that year I attended a computer show in London as an exhibitor selling my one product, I was please that I sold about 19 copies that day.
Back in the 80’s, before Microsoft wrote Windows my company had our own multitasking/task switching front end for the Sinclair QL called Taskmaster, this gave you multiple programs running in their own windows, all the programs multitasked, this meant that they all ran at the same time, you could set your database printing out labels and still use your wordprocessor or any other programs at the same time. Also included in the package was a file handling program similar to Windows File Manager, a pop up notepad and pop up calculator which once closed with a two key combination transferred the text out of the notepad or the result from the calculator to the underlying program. This allowed, for example, the ability to be working in your accounts package and, with a simple keypress up popped up the calculator, you could perform your calculations and then by pressing two keys the calculator closed down and as it disappeared it typed the result to the input box on your accounts package, the notepad worked the same way. This software also gave you a macro recorder and player language which could operate ANY program running in your machine thus automating common tasks. A software based printer buffer which was configurable to use spare ram saved customers the cost of buying the only other alternative at the time which was hardware printer buffers which were expensive. When you switched on your QL, Taskmaster remembered what programs you were using when you closed it down and they were loaded up ready to go.
In 1987 my company Sector Software released a spelling checker for the Sinclair QL by the name of Spellbound, this checked your spelling in real time as you typed, this is a feature that many thought that Microsoft invented in their recent Microsoft Office software, we were doing this ten years earlier than Microsoft. Spellbound spelling checker did not only work within a wordprocessor though, by linking itself in to the keyboard input queue it worked exactly the same in ANY program running in the computer, for example you could be in your accounts package, spreadsheet or even a game and still turn on the spell checking by simply pressing a two key combination, all your spelling from that point onwards being checked as you type, pressing two keys switched it off.
I noticed an increase in the demand for tuition from people wanting to learn to write their own programs, in the 80’s this became an integral part of the services I provided. It would later lead to a lifetime of teaching computer skills.
After realising that many people were experiencing difficulty programming databases, Sector Software released Flashback, this was a pop up database which could be called up at any time with two key presses, it was very simple to use and configure. When it was closed down Flashback would either simply disappear, or it would transfer the current record in to the underlying program at the programs cursor position.
In 1987 I started my own Bulletin Board. For those who do not know the term, this is a system where my computers answered the phone. My bulletin board ran from 6pm (after the close of business) through to 9am the following morning. This allowed people to use their computers to log on to my computers, leave messages, talk to others and download software. This was an online meeting place for computer users with modems to dial up in a similar way to the way the Internet is used nowadays.
In the mid 1980’s I attended ZX Microfairs at the Horticultural Halls, Westminster, London as an exhibitor. I then decided to hold my own shows in the North West. Seven very successful computer shows were held at Stokes Hall, Leyland, Lancashire at the rate of two or three per year. These were the first computer shows in the area. I did not continue organising computer shows due to many others getting on the bandwagon and starting competing shows in the area, these were box-shifter shows as they still are today, my shows were attended mainly by the people who wrote the software, you could chat to the authors direct as they sold you the programs.
The first computer show in the North West was big news, it was featured in the Lancashire Evening Post as well as other local newspapers, Radio Lancashire brought their outside broadcast van to the show because it was something so new. They interviewed me live on the radio amongst the stalls before they went around the show with a radio microphone, talking to people asking them questions like “what it was like to attend a computer show” and “what have you bought”. Little did I know how from these first beginnings that computer shows would swamp the area. The first show I organised was attended by about 2000 visitors, which at the time was an amazing response.
In 1988 I bought a Commodore Amiga and started converting my typing tutor ‘Touch Typist’ to this machine, Touch Typist was a best seller on the Sinclair QL and soon became even more so on the Amiga. I later converted Touch Typist to run on the Atari ST and the Acorn Archimedes. I became a regular exhibitor at computer shows from Scotland to Germany and Belgium. I was exhibiting at Schloss Bedburg (Castle Bedburg) in the town of Bedburg in Germany one year and saw a Sinclair C5 parked outside the castle, I could not resist the temptation to take it for a quick spin around the castle grounds, luckily I was not caught before I parked it up where I found it.
I had one of the first Z88 computers in the country when I was asked by Clive Sinclairs’ company Cambridge Computers to beta test their machine. After a trip down to Cambridge to sign the non disclosure agreement and take possession of a Z88 I set about testing the machine and wrote the first QL to Z88 link kit, this was followed by an Amiga to Z88 link kit. These were file transfer and print spooling programs which allowed you to transfer your data to and from your laptop computer.
The Z88 was similar to a modern tablet device, it was A4 in size, rand on its own internal batteries, had software built in such as a wordprocessor, database, spreadsheet and Z88 BASIC programming language.
After obtaining a licence from British Telecom, I released STD Index on the QL, Amiga and IBM PC, this was British Telecom’s dialling code database of UK and foreign numbers on computer disk with my own search engine, this was very useful for reverse searching numbers.
Demands for formalising the computer skills of my students led to my home office becoming an RSA (Royal Society of Arts) registered Test Centre in the early 1990’s. This allowed me to deliver courses run by RSA, the CLAIT (Computer Literacy and Information Technology) course was ideal as a starter course in computing and was adopted for my students.
My next software release was Wordsmith on the Amiga, this was a crossword, anagram and puzzle solver for crossword and competition addicts. I found out that this software was also being used in schools to help children find rhyming words or words on a particular theme.
Because of a personal need for an instant reference to the contents of technical articles I wrote Shopper Index . This was a database of Amiga Shopper magazines contents in a very fast 100% machine code stand alone search engine. This gave readers of this magazine instant access to years of Amiga Shopper magazine articles, letters, reviews and tutorials all wrapped up in my very fast search program. As well as being on sale to the general public, the editor and staff at the magazine also used my software to keep track of their own content!
Tandy’s educational arm Intertan contacted me to arrange for me to write a link to their WP2 computer. This worked in a similar fashion to my Z88 link, allowing up and downloading of data contained in the WP2 for archiving on a home computer or spooling the documents to the printer.
After being sent a digital camera by Fuji in 1997 and one from Sanyo in the same year I set about writing software to link these to a computer. By this time I had become known as a person to go to for communication links between various pieces of technology.
I wrote software to calculate prisoner sentences and release dates according to HM Prison Service rules. This software calculated a prisoner’s release dates for either consecutive, concurrent or mixed consecutive and concurrent sentences. This took into account time spent in custody (police or otherwise), ADA’s(additional days awarded) ADAp’s and a host of other variables. Data entry was simple and fast, the calculations were even faster, taking no more than a few seconds to calculate a complicated record, something that would sometimes take hours when done manually.
This program was originally written on the Commodore Amiga and was converted to run on IBM compatible machines after major problems in the Prison Service with doing the calculations manually ( You may remember the time when 500 prisoners were let out early when they found out that they had been calculating their release dates wrongly). The software knew all the rules and the amendments to the rules issued over the years. Output was to the standard sentence calculation white/pink/or blue forms complete with a sentence chart. The Home Office had originally said it was too complicated to computerise, which is how I ended up writing the software (I like a challenge).
I rewrote my best selling software Touch Typist for the IBM compatible market. The software was converted from the Amiga version of the program by the same name. Touch Typist is a typing tutor which sold over 100,000 copies on the Commodore Amiga, Sinclair QL, Atari St and Acorn Archimedes. One magazine reviewer said that “compared to Mavis Beacon and Intellitype (it’s closest rivals) Touch Typist is a lot more straightforward and rewarding to use”, need I say more.
Touch Typist was released on CD ROM for Microsoft Windows and a short while later was released as a software download. This was released as an automated online payment/download system at a time when paying for and automatically downloading software online was not a common thing to do.
Since the 1980’s I have written various custom software packages for local businesses to handle customer details, invoicing and data conversion. I am usually called upon when a business has large amounts of data that needs conversion from one format to another. I design and write custom software to handle the job automatically.
I do some website design work but that is not one my main activities, it was in the late 90’s and early 2000’s, but then the market became saturated with designers, so instead I specialise in gaining visitors to existing websites by a multitude of techniques from simple Search Engine Optimisation through to operating my own specialist software to market websites. My office staff now handle all the website, server, seo and online work for our customers, allowing me to get on with other projects.
I have been operating in the virtual world of Second Life since January 2007. I use Second Life to organise meetings and training sessions, I build, write software and generally learn all there is to know about Second Life. This platform is excellent for some businesses and I have made many new friends, customers and business contacts through this medium. I was the first person in the UK offering Second Life courses back in 2007.
I have done a lot of filming, editing and producing online training content for myself and for other people over the years. Although I first had video on my website in 2001, I only started producing podcasts (for Itunes etc) in January 2010. From an early date I used to deliver talks to local companies telling them that videos, podcasts or Internet TV was the future medium for businesses wanting to make an impact on the web. Today my content is consumed in online courses via my own and other websites.
With the growth of mobile phones came the growth of software developed for phones. In 2010 I started writing software for mobile phones, this was mostly internal use software but I currently have a few projects on the go for the Android operating system and now make a living from adverts in mobile phone applications and games.
Because I found it difficult to be in many places at once, I decided to move some of my courses online. This allows me to train a greater number of people, and not be restricted to where I can train based on geography. The first of these courses to be released was my Online Photoshop Course to replicate the content from my Photoshop classroom training. This led to the development of various online courses in programming, computing, games design and GCSE courses for teacher training.
I have developed courses for teachers to learn about the Raspberry Pi, Scratch, Visual Basic, and Python programming languages. I am also very busy delivering courses on GameMaker Studio.
Nowadays I get a lot of my work from www.codecollege.co.uk website, and I work freelance for other training organisations who require my skills. You may meet me on a programming course, when I am exhibiting at an education show such as the BETT Show, or maybe as an attendee of Techcamp, where I am a lead instructor.
I have always been interested in flying (I used to work in the flying school at Blackpool Airport at weekends). So I decided to become CAA licenced to do commercial video and photography with my DJI Inspire. This craft weights 3kg and can travel at 50 Miles Per Hour. it is an idea craft for producing aerial shots for websites, film companies, businesses, for creating 360 degree panoramas, site mapping for archaeologists and much more. Working with the UAV (Unmanned Aerial Vehicle) makes life more interesting as well as providing a good income from film and related work and aerial photography for customers websites.
I have released three skills(applications) for the Amazon Echo, Amazon Fire TV and other Alexa enabled Devices and have several more in development. Writing for voice interfaces is interesting and the devices that support it have given me some great ideas for future applications. I have written two skills to help GCSE Computer Science students learn and revise at home and have written one for accordionists. This is an interesting market, and I am developing my skills in it when I have time.
A part of my work that I really enjoy, is delivering face to face and online courses in Gamemaker Studio (from YoYo Games). I have used Gamemaker for many years and I really like its ease of access for beginners and its power for advanced users. I was a beta tester for the new Gamemaker Studio 2 from early 2016 onwards and deliver regular training sessions in the use of Gamemaker Studio for rapid game development.
This has been a short overview of what I have done and what I get up to, I will update this in my spare time, if I have any !!!
and on computers, then afterwards I enjoy my hobby… which is working on computers!
| 4.748198 | 1.765885 | -2.937635 | 2.445283 | 5.62075 | -3.036335 | 2.675109 | 1.361243 |
51,756 |
Monitor Risers & Stands There are 44 products.
This riser adjusts from 75 - 110mm in height to promote comfortable working conditions and prevent aches and strains associated with extended computer use.
The Fellowes Black Smart Suites Monitor Riser is a height adjustable monitor base that helps to position your monitor at a customisable height to reduce aches and strains associated with extensive computer use.
Raising your computer to a level that is more natural and comfortable, the Fellowes I-Spire Monitor Lift is perfect for strain free use of your computer. With a secure design that is sturdy, you donât have to worry about your monitor being unsafe or falling off.
For an easy and stylish solution to the positioning of your monitor, you need this Q-Connect monitor stand. Q-Connect provides you with products that combine the highest level of quality with the highest level of value.
| -3.989946 | 0.808913 | -5.843998 | 0.944374 | 1.85835 | -7.379515 | -4.734224 | -0.568413 |
3,514 |
Photo of Nissan Murano 192342. Image size: 1600 x 1200. Upload date: 2018-11-30. Number of votes: 1.
(Download Nissan Murano photo #192342) You can use this pic as wallpaper (poster) for desktop.
Vote for this Nissan photo #192342. Current picture rating: 1 Upload date 2018-11-30.
| -6.753412 | 0.116869 | -11.416026 | 0.434986 | -6.327981 | -5.831044 | -4.405908 | -1.436194 |
51,960 |
Hollywood is a seasoned rodeo horse with futurity and rodeo earnings, has been hauled extensively as a backup horse for Lindsay. He is very consistent and easy to ride with more personality than he knows what to do with. He would make a little girls dreams come true! Kid friendly and trust worthy horse that can win.
| 4.769448 | 0.232278 | -10.1962 | 0.379691 | 3.205063 | -9.189808 | -4.787015 | -1.036416 |
48,861 |
Plant Hoses operates the largest fleet of 24/7, 365 day on-site hydraulic hose service vans in Northern Ireland. Each service van is equipped with a radar tracking device to enable our service co-ordinators to urgently route our service vans to any location where immediate assistance is required.
This means that our fully trained service engineers are at any time within one hour of arriving at your site.
| 4.768178 | 0.826832 | -10.276991 | 0.531932 | 4.539295 | -6.35569 | -4.768656 | -0.607996 |
82,072 |
I’ve just sent an extended abstract for the XML Prague 2007 conference. I hope it will be accepted.
The most convenient approach to navigate over XML trees is to use XPath queries. But there is no reason to limit ourselves to XML only. Indeed, it’s useful to have XPath for navigating over arbitrary tree-like structures.
There are a number of projects, in which developers have tried to implement XPath over project-specific hierarchical data. Unfortunately, most of these attempts resulted in something that resembled XPath, but was not XPath. The problem is that implementing XPath, even version 1.0, is a difficult task.
We propose an alternative approach. Generative XPath is an XPath 1.0 processor that can be adapted to different hierarchical memory structures and different programming languages. Customizing Generative XPath to a specific environment is several magnitudes of order easier than implementing XPath from scratch.
The XPath compiler transforms XPath expressions to an executable code for the virtual machine. During execution, the code interacts with the native layer to access the tree nodes and its properties.
This paper explains what the virtual machine is, what is expected from the customization layer, and how they work together. Also, background information about the design and implementation of Generative XPath is given.
This entry was posted by olpa on Wednesday, February 28th, 2007 at 6:34 am and is filed under Generative XML, science, XSieve. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.
This method resolves my current problems, but I’m sure, that there will come also other questions I want to ask to the tree.
unless you really need the full XPath, it’s easier to reduce functionality.
The Virtual Machine is actually a runtime for the Scheme r5rs language. Unfortunately, there are no Scheme implementations written in PHP. Writing one is easy enough (2 weeks), but anyway it requires time.
| 4.760748 | 2.034319 | -3.649588 | 1.880156 | -3.200376 | -0.486494 | 3.425572 | 1.212166 |
17,768 |
Every moment of every day we are accompanied, guided and counseled by our spirit guides. Some stay with us for life, others join us for only a short time, but there is never a time we are alone. For most people their help goes unnoticed, called a hunch or good luck, we are always helped and guided.
Communicating and meeting your spirit guides on a conscious level is one of the great opportunities of the spiritual path.
In this workshop we will explore the role your spirit guides play in your daily life as well as looking at how you can commune with them in your day to day life. We will also briefly explore the chakra system and how you can use it access your higher self.
Finally we will move through a guided meditation walking through the chakras and finally greet our spirit guides in the crown chakra.
| -5.273776 | 1.017372 | -1.943544 | 1.805593 | 4.34433 | -1.355414 | 3.285604 | 0.863169 |
76,930 |
Discover snow-dusted peaks and wildflower-strewn meadows.
5 of the best apartments near Florence’s most panoramic viewpoint.
Four of the best apartments around the city’s 18th-century castle.
Go for Olympic gold or rule the ice disco with our guide to the best ski resorts for kids.
4 self-catering properties around Milan’s medieval stronghold.
4 apartments in walking distance of the 18th-century imperial residence.
Monasteries, mountain lodges and medieval stone houses – Italy does hostels differently.
From sculptures made entirely from flowers to acres of fragrant roses.
Stroll through medieval towns or wine and dine the weekend away.
From cleaning the coast to caring for wildlife in the Australian outback.
From chaotic, racer slides to calming saunas, there’s something for everyone.
Live the life aquatic on a sensational sailing trip around any of these islands.
An immersive 'bikepacking' travel experience promising adventure and stupendous scenery.
A guide to the most unmissable coastal spots across the archipelago.
Track wolves through the mountains, lynxes in the forest and beavers in the floodplains.
Luminescent waters, revered islands and sea monsters await.
There is so much more to discover beyond Lake Garda or Lake Como.
| 4.762574 | 0.987811 | -4.033576 | 1.086244 | -0.401487 | -4.48603 | -4.619507 | -0.01969 |
37,566 |
Bassmaster Radio is brought to you by Enigma Fishing and Visit Anderson.
Bassmaster Radio, a weekly program focusing on professional bass fishing, airs on more than 100 radio stations nationwide. Hosted by veteran broadcaster Thom Abraham, a passionate bass angler and tournament fisherman from Winchester, Tenn., the one-hour program is available to 126 stations on the SB Nation Radio network coast to coast, as well as on additional stations in Kentucky, Tennessee and Alabama. Check your local listings to find the time it will air, or listen to it on Bassmaster.com every week.
You can subscribe to Bassmaster Radio in iTunes, Google Play or use this link in the Podcast app of your choice. You can also search Spotify for Bassmaster Radio and listen to the latest episodes.
Also, each week you can listen to the show embedded below.
| 2.469554 | 0.696997 | -8.346557 | 1.244301 | 3.481358 | -8.185091 | -4.768505 | -0.51911 |
22,296 |
Record Store Day 2015 provided lots of vinyl highlights, but with so much to choose from it can take a while for the dust to settle and appreciate what you might have got – and what you might have missed.
Fact is I missed the best damn thing released on Record Store Day. I saw it, but with so much stuff already in my hands I started counting my pennies and kept walking. However, curiosity got the better of me, and I streamed the single, and then realized what was really happening… this was “THE” thing to get. Sure Hollerado was releasing a single for “Firefly” in green glow in the dark vinyl that was epic looking, but the title 111 Songs wasn’t just a title – It was a statement of facts – there was actually a download card with the single for one hundred and eleven songs! How many bands give you over a hundred songs for the price of a vinyl single – no other band people… no other band ever!
Hollerado is a power-pop outfit whose home base is ‘now’ Toronto (they formed in Ottawa) and have been putting out quality tunes since 2007. They’ve been runner ups for Junos (Canadian Music Award) on three occasions. Their last record White Paint is filled with some serious harmonies and presents a level of word play that is missing from most of the rock oriented bands that have recently presented themselves. They have spent the last few years touring with The Flaming Lips, Weezer, Passion Pit, The Dead Weather and a few others.
111 Songs is a gift for fans who pre-ordered their last record with one song written for each person and completed in less than two years. It is ultimately a huge workload all the more incredible as guitarist Nixon Boyd was battling testicular cancer (he’s fine now).
Anyway, I’ve been calling a few of my local record stores with no luck, but… it can still be ordered… YAY! While the band site, and record label do not have it, there is still a place.
So, if you like to rock out and toss your hair around to the sounds of something worth getting excited about – order this… (and as Stan Lee would say) Nuff said!
| 2.123791 | 0.727137 | -6.393377 | 0.058128 | 3.989363 | -5.250331 | -4.761121 | -0.548989 |
21,264 |
Please note that if your Carrera has a metal bracelet & you wish to change to a leather strap, you will need a new clasp as well, as the clasp from a metal bracelet cannot be used with a leather strap - see our clasp section for details.
A clasp is not included with the strap - you must remove the deployment clasp from your existing leather strap and transfer it to the new one. The strap CANNOT be used with a pin buckle.
| 4.768301 | 0.274067 | -11.425126 | 0.485253 | 3.592863 | -9.99132 | -4.282226 | -1.076544 |
78,794 |
Agents and business managers that work with artists, performers and athletes assist their clients through promotion with current or prospective employers. They may also work on contract negotiation and business matters for clients.
Find schools that offer Bachelors Degree in Business Administrations programs!
| 4.765286 | 0.902945 | -11.462666 | 1.676375 | 4.321377 | -11.198638 | -4.786527 | -0.626809 |
37,941 |
A built-in, three-layer microfiber terry soaker absorbs an amazing seven times its weight in liquid. The soaker is topped with our stay-dry microfleece which keeps your baby feeling dry. An additional layer of terry lies between the microfleece and PUL body of the diaper providing a last line of defense. The soaker is sewn in on one side (at the top of the diaper), which makes adding extra absorbent layers a cinch and tremendously decreases drying time...it's the fastest drying diaper we've ever created!
| 4.768461 | 0.512571 | -5.404384 | 0.47101 | 5.826573 | -3.808337 | -4.770247 | -0.236933 |
3,217 |
Tailored to your needs and your lifestyle, designed to suit your unique body type.
Support the healing process where there is injury.
Relax the mind and feel rejuvenated.
Be strong, flexible and positive – on and off the mat.
Find out how yoga can help you personally.
Call or email me to discuss your needs, or to book a trial session.
| 4.766004 | 0.353862 | -9.984085 | 0.849609 | 4.352334 | -10.30827 | -4.591066 | -0.877009 |
17,956 |
A STATIONERY BRAND INSPIRED BY REAL LIFE.
We are obsessed with stationery – period. This passion for pretty & practical paper is how we got into creating our dream stationery products for our desks.
Being created by students & female entrepreneurs, Supplied by Lily stationery focuses on creating stationery that is aesthetically pleasing for the eye, yet also helps any student or boss girl or guy out there with goal setting & achieving.
Supplied by Lily stationery loves you! Interacting with you is what keeps us going. We are constantly looking for struggling students and working girls & guys to make your life easier, and organized.
Forgetting last minute deadlines, late night study sessions, wondering the last time you slept for at least 8 hours a night: Life can be tough. We heard your struggles and keep improving our stationery to boost your productivity and start killing the game.
Every dream starts with a dreamer. Don’t be scared to dream big. The world is yours! The Supplied by Lily Luxury Lifestyle & Student Stationery will help you to overcome that fear with inspiring questions and quotes each week. In style of course.
After setting your goals, it’s time to make a plan. Use one of the Student or Lifestyle Desk Planners – depending if your goals are study or career orientated – to actualize your goals, the A4 or A5 Spiral Notebooks to get the work done and the To Do List to track your different study, work, and other activities.
Dream, plan & achieve. With a good plan, the right mindset and a lots of motivation you can make your dreams become reality. Supplied by Lily is more than just a brand. It’s a life changing statement: Supplied by Lily, Achieved by You.
| -4.114043 | 1.045208 | -5.425366 | 1.146372 | 6.206607 | -4.944461 | -2.534249 | -0.023814 |
37,570 |
What is an Integrated Priority List?
The acronym IPL – pronounced [ipp’l] – stands for “Integrated Priority List (IPL).” It applies to the list of a Combatant Commander's highest priority requirements, prioritized across Service and functional lines, defining shortfalls in key programs that, in the judgment of the Combatant Commander, adversely affect the capability of the combatant commander's forces to accomplish their assigned mission.
Is a Project Charter Important and Do I Even Need One?
Compared to a lot of other documents developed when planning a project, like a Project Management Plan, Cost Benefit Analysis, or Risk Management Plan, the Project Charter seems small. Just based on size, many Project Managers see it as an afterthought and think their time could be better spent on other tasks. But, this little document packs a powerful punch, and is actually the most important of all the documents needed for a project.
Enterprise Architecture: What is it and what’s the benefit?
Organizations these days often talk about Enterprise Architecture (EA) and how it plays a key role in their IT Organization. While this is true, it’s not completely accurate. This is where many organizations miss the boat on EA - forgetting that while there is an IT component to EA, it is not strictly an IT responsibility.
What is the value of a PMP (Project Management Professional) certification?
| 4.766556 | 1.66331 | -3.093174 | 1.94857 | 4.390994 | -1.92998 | 3.292015 | 1.250259 |
79,881 |
The ICOM Kyoto 2019 official theme, “The Future of Tradition,” relates to a well-known ancient Chinese proverb from the Analects of Confucius: “Know the old to discover the new” (pronounced wengu zhixin in Chinese and onko chishin in Japanese). This phrase is often discussed in the context of the arts: For artists to be truly innovative, they must have a deep understanding of the work of their predecessors. For this conference, we welcome papers that discuss the competing or complementary interplay between tradition and creativity and innovation in works of art, museum collections, and artistic traditions.
For the first ICOM General Conference ever held in Japan, ICDAD will hold individual sessions and offsite visits for its own members for three days (2, 3, and 5 September) and will hold joint sessions with ICFA and GLASS, two other international committees focusing on art and art museums, for one day (4 September).
Information about the conference program, hotels, events and excursions, visas, and other general information may be found through this website. You cannot register for the General Conference directly through ICDAD. Please note that the deadline for Early Bird Registration is 30 April 2019.
The organizers reserve the right to decide the length of each presentation depending on the quantity and quality of applications. We hope to be able to include as many high quality presentations as possible. If you have a preference as to your presentation length, please state so at the bottom of your abstract.
Abstracts of one page or less are due by 28 February 2018. Please email abstracts to [email protected]. All abstracts must be submitted in English.
Please submit a 100-word presenter’s bio and a headshot photo together with your abstract.
The ICDAD General Assembly is tentatively planned for the end of the last session on 2 September. Plans for future annual meetings and other information for members will be announced at this time. Information will also be provided at this time about the ICDAD Board Elections, which will take place by email after the ICOM 2019 Kyoto General Conference.
On 5 September, each of the three International Committees will host individual tours and site visits curated especially for its members. ICDAD is planning a program of Kyoto museum and other site visits for this day to introduce its members to the rich decorative art traditions in Japan’s ancient capital and cultural center. Due to visitor limits at some sites, we may divide into smaller groups. Details about these visits will be posted in the ICDAD session room at the ICC Kyoto during the conference, with sign-up on a first-come, first-serve basis.
For information about planned offsite visits of ICFA (http://network.icom.museum/icfa), and GLASS (http://network.icom.museum/glass), please refer to their websites.
ICDAD is not planning special excursions for this day, so please sign up for excursions through the general ICOM Kyoto 2019 website http://icom-kyoto-2019.org/excursion.html.
| -5.062749 | 1.385277 | -4.101081 | 1.871881 | 5.730912 | -3.396577 | -1.844547 | 0.470439 |
19,390 |
This is the bundle hoverboard and the hoverkart dancing yellow color ,with use manual ,charger carry bag.
Nice hoverkart! The strap that connects to the hover board broke after only one use which was disappointing, but they’re excellent customer service sent a replacement strap immediately.
| 4.757135 | 0.030295 | -11.114844 | 0.248717 | -5.191579 | -7.860918 | -4.774717 | -1.326959 |
56,297 |
OTTAWA — The Canadian Chamber of Commerce has asked for immediate federal funding to stop the spread of the destructive mountain pine beetle as it threatens to spread across the country.
Chamber CEO Perrin Beatty says in a letter sent to Natural Resource Minister Amarjeet Sohi that warmer winters have allowed the beetle to spread east and that the threat is at a critical juncture.
“The infestation will soon be in reach of the forests that border Alberta and Saskatchewan. If this forest becomes infested, there will be a clear path for the beetle to spread across the rest of Canada,” wrote Beatty.
Alberta has been largely left to fund efforts to keep the beetle at bay, spending more than $500 million since 2004 to control the beetle’s population, he said.
The federal government should recognize that the infestation is of national significance and to provide funding to match the threat, starting with $100 million to help fund Alberta’s efforts, he said.
A spokeswoman for Sohi said the minister thanks the chamber for its input, but did not commit to specific funding.
“We understand the threats that forest pests pose to Canada’s forests and we remain committed to supporting healthy forest ecosystems and good middle class jobs,” said Vanessa Adams by email.
According to a report to the Canadian Council of Forest Ministers, British Columbia lost more than half of its salable pine timber between 1995 and 2015 due to the beetle, which will cause the provincial economy to lose out on tens of billions of dollars in the coming decades.
Beetle-ravaged trees also burn at higher temperatures, making forest fires more severe and harder to control.
| 4.763135 | 2.376925 | -3.371066 | 1.667708 | 6.42846 | -1.039854 | -1.783234 | 1.171376 |
29,571 |
On a mission to encourage social good by rewarding micro actions, Giovanna Mingarelli is the back-bone behind MC2, an Ottawa-based tech startup offering Software-as-a-Service (SaaS) chatbots for social action.
Mingarelli is the CEO and co-founder of MC2. A sought after public speaker and thought leader in the areas of entrepreneurialism, civic engagement, business and socio-political events internationally, Mingarelli a globally recognized public figure with publications in the Huffington Post, Globe and Mail, and citations in the Harvard Business Review and Forbes.
Having worked extensively in the field of political and digital communications, Mingarelli served in the office of a former Prime Minister of Canada and was named one of Canada’s Top 100 Most Powerful Women by the WXN.
In this week’s #StartupPodcast, host Rivers Corbett talks to Mingarelli about how governments can engage with technologies to build greater engagement, trust, and accountability.
| 3.401758 | 1.260765 | -4.658604 | 1.246447 | 5.45336 | -3.55522 | -4.722966 | 0.237698 |
69,541 |
With dual true convection cooking, you’ll get consistent heat no matter how big or small your meals are.
Flex Duo Technology – A removable divider that converts one oven to two to cook multiple dishes at once.
Dual convection – Two powerful convection fans that circulate heat cooks food evenly and saves time.
| 4.758522 | 0.857897 | -4.996575 | 1.508827 | 4.085939 | -2.644234 | -4.719139 | 0.221609 |
91,165 |
Happy New Year! Now, Let’s Make Changes!
Resolution Success in the New Year!!!
Compassion is the Antidote to Judgment!
Blame It On Rio 2016!
| -6.700924 | 0.037454 | -8.294079 | 0.24076 | -3.386317 | -6.287539 | -4.769645 | -1.29766 |
88,543 |
This is a placeholder page for Larry Blackwell, which means this person is not currently on this site. We do suggest using the tools below to find Larry Blackwell.
You are visiting the placeholder page for Larry Blackwell. This page is here because someone used our placeholder utility to look for Larry Blackwell. We created this page automatically in hopes Larry Blackwell would find it. If you are not Larry Blackwell, but are an alumni of Balboa High School San Francisco, CA, register on this site for free now.
| 4.765798 | 0.145076 | -10.272711 | 0.261643 | 3.629586 | -9.776095 | -4.680094 | -1.120078 |
47,978 |
Summary: Applies analytical and computer knowledge to design, verify accuracy and distribute reports to both internal department as well as corporate management. System knowledge of database files to extract specific data based on adhoc requests from various areas of the corporation.
Essential Duties and Responsibilities: The essential duties and responsibilities described here are representatives of those that must be completed by an employee to successfully perform this job. To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. All duties and responsibilities must be completed with the appropriate policies, procedures and guidelines established by SMP. Other duties may be assigned.
Provides training and/or assistance to others, within their area of expertise, of the data management systems.
Collects records and trends and evaluates performance measured against goals and budgets.
Utilizes available computer systems resources to assist in analysis to support management's quest for performance improvement.
Assist with the reviewing of proposed inventory plans for completeness, accuracy, and organizational objectives.
Creation, generation and maintenance of detailed data analysis reports for both internal departmental use as well as divisional requirements.
Education and/or Experience: Bachelor's degree from four-year college or university.
Computer: Proficient in the use of computer systems to input, retrieve and analyze data.
| 4.765605 | 1.765788 | -3.690395 | 1.954594 | 2.873966 | -0.117352 | 3.115561 | 1.30663 |
58,138 |
Leather gear gaitor with double stitches. Please select the color you like. See our color card in content "information" and write it by your order. You can also have colored stitches! Only for manual transmission!
| -3.504387 | -0.046495 | -11.512785 | 0.186318 | -4.699842 | 0.952595 | -4.709765 | -1.051741 |
63,525 |
If you have sensitive, rosacea, post surgery or acne skin that cannot tolerate regular skin care products, Skin Rx products are your answer. Here are a few specialty kits made for our rosacea clients. Together these products will help nuture and protect your skin.
| 4.754343 | 0.204476 | -9.697964 | 0.523619 | 4.674679 | -8.749357 | -4.771585 | -0.908432 |
97,615 |
The Gift & Lifestyle fair is a trade only event for businesses registered within one of our many show categories. Registration is a FREE, simple process and only takes a few minutes, simply click the button below to access our Visitor Registration Portal and complete the details within.
Once you complete your registration you will be emailed your Visitor Badge, which you must print out and bring along with you to the show. Please ensure the details on your badge are correct, as you may be asked to provide a form of identification with matching information on the day. If you have any issues with receiving your badge please contact Fair Events on 02 9452 7575 or [email protected].
| -4.48972 | 0.38378 | -10.2403 | 0.513885 | 4.358569 | -10.013535 | -4.068368 | -1.160801 |
48,607 |
See more What others are saying "13 Easy Ways to Get Rid of Blind Pimple Fast" "Blind pimple is a swelling-like bump which is pinkish/reddish in color.
We chat to the experts about what blind pimples are, how they form, and the best way to get rid of them. So that means there are up to 25 corporate psychopaths.
| 4.768949 | 0.87732 | -10.279975 | 1.407389 | -5.172521 | -4.19401 | -2.309813 | -0.309949 |
9,392 |
Devices and systems on both sides of the electric meter can help the grid function more efficiently, manage variable generation, and be more resilient under adverse conditions.
Research within this technical area falls under four main activities with related goals.
The Plug & Play DER Challenge seeks interoperability solutions to lower integration costs, increase system performance, and enhance capabilities. Concepts are due September 7, 2018.
| -3.37969 | 1.674158 | -5.348395 | 1.754198 | 4.599463 | 2.195219 | 1.041272 | 0.97364 |
30,713 |
The Tribal Welfare Department website complies with Guidelines for Indian Government Websites and World Wide Web Consortium (W3C) Web Content Accessibility Guidelines (WCAG) 2.0 level A. This will enable people with visual impairments access the website using assistive technologies, such as screen readers. The information of the website is accessible with different screen readers, such as JAWS, NVDA, SAFA, Supernova and Window-Eyes.
| 4.768661 | 1.518784 | -0.837364 | 1.85483 | 5.364332 | 2.135064 | -3.250636 | 1.190737 |
39,344 |
What is an ICO cryptocurrency?
It is crypto currency that is often in the news. Today initial coin offerings in trading have made people to think about this new trend of trading. Initial coin offering is popular as ICO. It is one and the same thing. An ICO is the short form of initial coin offering. In this type of trading it is possible to earn very large returns from the small investment. It is a new way of raising the initial capital of cryptocurrency. The first release of the currency is offered to early adopters in return for an investment made in conventional currency. It is important to know about the cryptocurrencies. These types of currencies are in the form of coin or token. It can be changes in your own currency during the time you make the exchange.
An ICO works in a very similar way provide the funding to the crowd. It is bitcoins and ethers that are in the form of coins and token those are used for trading. They both are the most popular in cryptocurrency business. These two are mostly used in any type of business online. One can buy these cryptocurrency and can start trading in any field of business. To know the best way of trading then you can have the best method. The best way of trading cryptocurrency is ICO pulse. An ICO list is reliable way of doing the business with any type of cryptocurrencies.
This is a kind of list in which you can have all the information of trading. The companies and all the investors are displayed in the ICO list. It usually publishes full details of how the new currency is going to work. Along with the details of what other currencies will be accepted as an investment in the initial release of the coin. You can even see the time limit that will be on the offering. Best ico coin is for those people that are found of doing the proper trading in which one can gain faster. The small investment can provide large profits. This is the list that helps to search for the company that will offer shares for sale to the public to raise capital.
In the list you can see the minimum total capital raised figure. The time limit can be seen on the list and in that time if you invest then you are in the list too. If the time limit is finished then you are not able to invest. The cryptocurrency business is legal in many countries. In early years this type of business that is done with token or coins was not popular but today it is the most demanding. The ico list provides the perfect way of trading this new type of business.
| -4.178363 | 2.236956 | -5.042021 | 2.014061 | -0.186186 | -4.315462 | -1.446105 | 0.556625 |
50,290 |
Tim likes long walks on the beach and romantic dinners…wait…what is this for? Oh. My mistake.
The closest Tim Murphy ever got to Lake Charles before now was driving through moving from Houston to Nashville. Now he wishes he would have stopped sooner.
Show business goes way back in his family. His grandmother parachuted out of hot air balloons in the circus starting when she was 8 years old. Tim has been full of hot air at least that long.
He is new to our area but not to country music. He has worked with top rated radio stations in Seattle, Houston, Nashville, Los Angeles, Dallas, and Pittsburgh. He’s also done time in the music business working with legends like Dolly Parton and The Nitty Gritty Dirt Band.
Tim is loving Lake Charles and so are his fur kids, Cosmo (a Yorkie) and Nellie (something else).
You can catch him here on the Big KYKZ 96 afternoons at 2.
| 4.767901 | 0.661066 | -8.374434 | 0.398103 | 3.408448 | -6.504422 | -4.787288 | -0.619674 |
27,791 |
Of all the excellent rock-en-Español bands in and passing through New York, Pistolera represent the elegant, catchy, tersely literate front. Their energetic, businesslike set at Joe’s Pub last night further cemented that reputation, mixing songs from their three albums which draw equally on ranchera ballads, American powerpop and older, more rustic Mexican styles. Frontwoman Sandra Lilia Velasquez kept her vocals smoldering and low-key for the most part, although she showed off a surprisingly powerful upper register on the most dramatic (and most intensely applauded) song of the night, a big, wounded border ballad. The bassist swung hard through his relentlessly rising, melodic lines as the drummer switched from straight-up, four-on-the-floor rock, adding a funkier edge or a scurrying shuffle beat on several other numbers.
Otherwise, the show was like Very Be Careful (with a better singer) playing Mexican rock. Not that Very Be Careful isn’t a great live band, or that the accordion isn’t a beautiful instrument: in the hands of Pistolera’s Maria Elena (a black belt kickboxer, as it turns out), there was a nonstop river of gorgeously plaintive tones sailing over the punch of the rhythm section. Too bad that other than vocals, that’s all there was in the mix. Pistolera gets their signature sound from the jangle and clang of their guitars, and throughout the set, the lead player was seldom audible and Velasquez hardly ever. Joe’s Pub isn’t known for good sound: this was a new low, and it doesn’t seem to be related to ongoing renovations which have shuffled the tables and bar seating.
But the band didn’t let it phase them. Even without the guitars, Todo Se Cae (Everything Falls Down) was an understatedly potent, anthemic reminder of the precarious state of the world. After alternating several similarly anthemic tunes, notably the irresistible, resolutely bouncy Nueva York (from their new concept album El Desierto Y La Cuidad) alongside a couple of pensive, minor-key laments, they closed with a practically gleeful version of the banda-rock hit Policia. “This is about when I got arrested,” Velasquez smirked, referring to the incident that inspired the song, when she discovered that it’s now illegal in this country for a woman to wear a bullet belt while boarding a flight.
An idea as to how Joe’s Pub might be able to banish the nasty feedback that plagues the PA system here, without turning off the guitars: why not do what the Rockwood Music Hall does? The sound booth at both of the rooms there is up in the rafters, just as it is at Joe’s Pub. But Ken Rockwood’s people operate as a team: in the larger room, the sound engineer tweaks the frequencies while a colleague makes his or her way through the crowd, texting the engineer with any needed modifications. It works like a charm there. Or maybe Joe’s Pub ought to take Rockwood onboard as a consultant: they sure could use him, or somebody like him, right now.
| 4.764647 | 0.947617 | -3.647538 | 0.475371 | 5.927555 | -0.964596 | -3.590962 | 0.252009 |
92,285 |
wow! I see I am not alone here! I haven't been late on a payment and yes they hound you like a week before your due again. They call and tell you to call them by 5 , they text you and say to call them by 5. They don't give up. And I'm not even late. They are rude and nasty! They drove me to the point that I voluntary turn my car in. Yes I did! Went to a real dealer Paramount Kia and was able to drive off the lot in a brand new 2019 Kia Soul with $350 down! That's right and my credit was a little over 600. It took about an hour and a half to seal the deal. What a different it made dealing with a real car dealership then these buy here pay here. Never again!! yes my credit took a hit. Not too bad , Its recovering just fine. I'm happy now!
THE WORST!!!!! They are very nasty and hang up on you!!! If you don't understand something they couldn't be bother with you. They all must hate life and there jobs!!!I I haven't been late since I got this loan. but the phone calls and text message are unreal. a week and a half before your payment is due . its non stop. I had ask them to stop and they don't listen. so now I block them. Im trying to refinance, if not 3 more horrible years with them. NEVER NEVER AGAIN! I hate my car because of them.The moment I pay this car off is the day I'm going to a real car dealer and buy a new car!
Didn't get the chance to get my tat, but just want to warn ya... I paid a 1/3 - 1/4 ($100) NON REFUNDABLE NO MATTER WHAT deposit and even though I gave them 24 hours that I needed to reschedule, they told me I would still lose my $100 deposit regardless. They have a 9 day rescheduling policy, so if you are good at seeing if unforeseen events will happen 9 days out or are psychic, this might be a good place. That artist seemed really cool and easy to collaborate with. Otherwise, i'd avoid the sham and find a shop with a reasonable rescheduling policy of 24-48 hours. I thought deposits are to protect both parties..? Not here though.
Ate there twice (gave them the benefit of doubt) food was warm to cold, service poor, had to ask for napkins, had to ask for silverware, priced too high. Never again!!
Unifour will do nothing but lie to you and then make your life hell. After setting me up with insurance themselves at the car lot I had no idea when my insurance payment was due. After 2 weeks of digging and calling multiple numbers - because they magically didn't have the info. - my insurance was cancelled. When I spoke with them and told them I would have it fixed the next day -and left another message stating the same thing because they had closed early - they repossessed my car that night knowing they would have insurance information the next morning. They will take the first chance they get to charge you an insane fee and offer payments on said fee that will make sure you cannot afford your already overpriced car. Do not buy from this company. Taking the bus or walking is better than the headache and trouble a car financed through them will give you.
Highly recommend Ink Therapy for everything from custom to cover ups. The majority of my tattoos are done there and I've never been unhappy with the art work or technique. Clean, professional environment.
| -1.31342 | 0.408228 | -6.4877 | 0.011547 | -1.338242 | -4.705955 | -4.76421 | -0.855811 |
62,570 |
The Law Society has responded to the Law Commission’s consultation on Leasehold home ownership: extending your lease and buying your freehold.
This consultation constitutes part of the Law Commission’s wider review of residential leasehold and commonhold under its 13th programme of law reform.
In it, the Commission makes provisional proposals for reform designed to enhance and improve enfranchisement rights and provide a new unified procedure for all claims designed to benefit leaseholders of both houses and flats.
The Commission has also set out options for reducing the price payable by leaseholders to exercise their enfranchisement rights, whilst ensuring sufficient compensation is paid to landlords to reflect their legitimate property interests.
to make enfranchisement easier quicker and more cost effective.
Leasehold reform is a complex and important task. There are different interests at stake. The Law Society recognises the scale of the problem, and we are keen to work with the Law Commission and the government to identify solutions.
| 4.765498 | 1.133672 | -3.770427 | 1.493404 | 4.335471 | -3.08686 | -2.083921 | 0.517373 |
52,132 |
Laserfiche—the leading global provider of enterprise content management (ECM) software—announced today that Josephine el-Koreh, Digital Banking Delivery Channels Manager at the Bank of Beirut, is the recipient of the 2018 Tom Wayman Leadership Award. El-Koreh was recognized for her ability to drive technology initiatives that position her organization for success in a highly regulated, rapidly changing industry.
The Bank of Beirut is one of Lebanon’s leading commercial banks, with a presence in 10 countries. Since 1999, el-Koreh has been a strong advocate of process efficiency at the bank and, in the last four years, she pioneered the use of Laserfiche across 85 global branches. By integrating Laserfiche into multiple systems and offices, el-Koreh has transformed key banking operations including validation, contract management and customer service.
Under el-Koreh’s IT leadership, the bank has improved transaction times, enhanced document security and increased staff productivity by 60 percent. The bank’s successful use of Laserfiche has also been recognized by the Laserfiche Run Smarter Awards and highlighted in Computer News Middle East.
The Tom Wayman Leadership Award was introduced in 2014 and honors an exceptional individual within the global Laserfiche community who exemplifies extraordinary leadership, vision and commitment to sharing the Run Smarter® philosophy. The awards ceremony took place during the Laserfiche Empower Conference 2018 in Long Beach, CA.
| -6.37812 | 0.97277 | -5.986979 | 0.761222 | 5.23009 | -5.97317 | -4.376567 | -0.44619 |
77,823 |
Scrap Metal Crusher. 9,Crushers Equipment - scrap metal by crusher is the preparation for recycling metal, which can help the environment and give a real boost to the economy.
The ultimate #1 Metal radio station in Las Vegas. Shows covering all Hard Rock and Metal Music. Shows include: Bangers and Mash, Classic Brunch, Into The Pit, Metal Underground, and Black Death.
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Crushing Metal Radio. 224 likes · 3 talking about this. Heavy Metal Music 24/7 including live hosted and featured shows.
| -5.837911 | 0.874396 | -8.742275 | 1.207776 | -7.833402 | -3.529851 | -4.762282 | -0.714129 |
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Since he was young Ali Kadhim was addicted to superhero comics and Jackie Chan films. He joined his local Tae Kwon Do club at the age of 12 and earned his 1st Dan Senior Black Belt at 15 before moving onto other martial arts including Shaolin Kung Fu and Goju Ryu Karate. He also pursued extreme sports such as inline skating, skateboarding and breakdance with his high school friends. All of these physical arts finally led him to Parkour.
| 4.767071 | 0.973329 | -4.041285 | 1.151754 | 4.925131 | -4.062532 | -4.77083 | 0.14661 |
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Edit October 2017: Moved all pictures in this thread to a new host.
After many months (years?) of lurking, I have finally started my build. It is as terrifying and scary as I thought it would be. I barely know how to hold a shop knife, let alone using it to trim a Stormtrooper suit... But I am trying my best!
I started trimming it, but due to more pressing matters taking priority, I had to postpone the build. It has been waiting in a box in my bedroom since.
Recently I started building again, and figured it is time to do one of these build threads.
I started with the arms and biceps. Thought it would be an easy start.
The specs states no return edge. Is this acceptable?
I hope to have the suit battle-ready by mid-September. I am spending my summer vacation at home, so I have lots of time to work on it.
You can take a little bit more off of the forearms.
Hi Simon, some of your cover stripes appear a bit long to me. Maybe you can shorten these a bit!?
From what maker is that armor?
Thanks for all advice! I have been tinkering with the arms and biceps all evening, and they are starting to look better.
Haha, yes, it was oddly satisfying!
I might sand it down some before moving on to the left arm.
I think I made the strips this long to hide the difference in height between the two halves. But it looks like it is possible to make them a bit shorter.
The armor is Troopermaster 1,5 mm ABS.
I've done some more work on the arms. I have removed more of the edge on both forearms, and the cover strips on the forearms and biceps. I had too much of an edge on the biceps, which made it difficult to hide the height difference. Took some of it off, and shortened the strips. I still need to smooth out the rough edges, but I need to do a supply run to get more sandpaper first.
Yesterday I also glued the shins. 20 mm wide strips in front, 25 mm wide strips back. I am happy with how they seems to have turned out, but I'll do my final judgement once I'm sure that the glue has set. It was a bit cold in the store room last night (14°C at the lowest), so I'll give it a few more hours before removing the clamps and magnets. Just to be sure.
I want to do the accurate shin hooks, but am a bit worried that the holes will rip after a while. Do any of you reinforce the holes in any way?
No need to worry about the holes ripping.
Who's skipping leg day? Not this recruit!
The glue on the shins has set nicely. The left shin did slide a bit due to poor clamping, but it will be mostly hidden by the knee plate. I might make som ABS paste and fix it later, but I will let it be for now.
I did a test fitting before I did the final cut and gluing.
I going to sand the edges some more. That right leg does not look right.
When I am done with that, I will glue the strapping. I made them with the help of a nearly 50 year old sewing machine – a Singer Golden Panoramic 670G from ca 1967.
After that, I will move on the knee plate. I'm thinking it requires lots of glue, clamps, magnets and patience.
What I did was put some glue on the inside edges of the kneeplate and the front of it that touches the coverstrip, then clamp it in place and kind of trickle more glue from the top into space between the edges of the kneeplate and the shin. You can do this in stages too.
The knee plate is glued and clamped, and should be done in about 20-24 hours. Possibly. The northern Norwegian summer temperature is working against me, wildly fluctuating between 10° to 25° on any given day. It has been difficult to maintain an ideal curing temperature in the room where I let my pieces dry. Never thought that would be an issue during this build!
While I wait for that, I have moved on to the helmet. I trimmed the teeth and eye holes back when I first got it. I decided back then that I wanted a black interior. I might have chosen the screen accurate green today, but it doesn't matter. Black is fine.
I've always found that a low brow looks more menacing than a high brow, so I did some fiddling and found my preferred placement. The brow is resting about 3 mm above each outer corner of the eyes, with a slight upwards curve. The center measures 5 mm above the eyes. I like this look, so I have mounted the faceplate.
After that, I started trimming the ears. And I have made a mistake. I overtrimmed the right ear. It fits nicely in the back, but have a huge gap in front. I wish it was the opposite.
I could try trimming the back some more, and moving the ear slightly down and back. The gap should become less prominent then. Right now, I am contemplating on letting it be, or obtaining a new set of ears. I don't know, I have to figure something out.
I would trim the back of the ear to allow you to pull the front closer to the tube. You may need to trim the circular part too just to help a bit. Don't worry if you have a slight gap, it's quite normal. People try to make a water tight fit when it isn't necessary.
Using pencil marks and sandpaper only (no scissors or powertools), I took some flesh off the back and the circle on the right ear. The gap is much less prominent now, and I'm feeling more confident that it will look good when mounted. Next up: the left ear.
Simon, remember once you put the screws in it will pull it closer to the tube and bucket so don't make any more changes to the ear until you see what it looks like mounted. You're on the right track!
Just a quick update. I've just checked on the knee plate. The glue has cured, but it has slipped slightly to the right during the night. It's nothing you would notice when looking at it.
You can try sliding in your exacto blade in there to separate it on just that section and re-glue it.
Another quick update, but no pictures today. Not much has been done since the previous update. I took the weekend off from the build, after having spent many hours on Friday trying to get the ears right.
Today I marked the placement for all of the split rivets, snaps, brackets and screws on the torso. I haven't yet decided if I want to do an accurate, permanent strapping with the split rivets, or if I want use snaps on the inside.
Now I have to let the glue cure. This is the downside to using E6000. It take forever to glue something as easy as straps.
The arm straps are mostly done. I still haven't done the one on top of the shoulder bells, with the sew-on snap connecting to the shoulder straps. I want to take more accurate measurements first, so that will have to wait until I actually have a shoulder strap to measure.
- Added insoles to my TK Boots to get a better fit.
- Glued latex handguards to gloves.
- Tried on the black compression undersuit, feeling like a ninja. But I'm a bit disappointed. It turned out that the pants have very visible, light grey seams that didn't show in the picture on eBay.
- Pretrimmed the belt ammo boxes and the thigh ammo boxes.
- Pretrimmed the drop boxes.
- Fitted and trimmed thighs. Started gluing them.
- Reinforced the aerator sockets on the helmet using Sugru.
I noticed something when working on the helmet in different lighting conditions. The plastic has yellowed. This has not happened to any of the other pieces, and as far as I know, the helmet are made from the same material. I'm trying to think why this has happened. None of the parts have been exposed to direct sunlight over time, and the box was not stored close to any heat source. The only difference I can think of, is that the helmet were wrapped in bubble-wrap, but I don't understand how that would result in yellowing. Anyway, it is not that noticable yet (I didn't notice it until now). And if the yellowing continues, I think I have most of the ingredients to make Retr0bright.
When I came home today, I noticed that lingering E6000 smell from previous legs in this build. It smells like hope and dreams and sticky fingers!
The thighs are coming together nicely. I had to reinforce one of the front cover strips, so that set me back 24 hours. The other one looks good for now, but the glue is still wet. Once I free up a couple of magnets, I will tackle the back cover strips. I keep coming back to the forums to check how wide they should be. The built-in search never agrees with me, but using Google site search, it seems like the consensus here is 20 mm wide. But also that they should be the same width as the shin strips for consistency, and mine are 25 mm. The screen used once were all over the place, so I guess it comes down to armour proportions and personal preferences.
Last night I heated and bent shoulder strap hooks. I first tried the method from one of the howtos on the site, but between the measurements and the grooves, I could not get it to bend right. Next I tried just bending the plastic over a flat carpenter pencil. The pencil I used is 15 mm wide and 7 mm thick.
That went surprisingly well. And I didn't even burn my fingers!
Right now I am working on the cover buttons for the belt. How large should the square be? I have marked 25x25 mm, which will fit snugly between the ammo boxes.
Ok a little over the top but I bet it got you fired up didn't it?
If you're interested I have a little bicep retaining clip tutorial on a AM build thread, follow the link and drop about 3/4 of the page, this may help.
| 4.73703 | 0.611576 | -4.899303 | 0.193 | -0.060979 | -4.37273 | -4.763841 | -0.4398 |
37,910 |
As a complicit minion in the State's appropriation of the monetary unit, Krugman perpetuates 'The State Theory of Money' myth that the sovereign's power to collect taxes and declare legal tender imbues a currency with ultimate value.
We don't want a pristine monetary standard untouched by human frailty as Krugman claims. We want freedom in the monetary standard untouched by the politicizing process.
Krugman actually struggles to assert that bitcoin is antisocial because he cites economist Paul Samuelson who once declared that money is a "social contrivance," not something that stands outside society. Samuelson is absolutely correct on that point and bitcoin stands firmly within society. It is no one's right to question why some place value on bitcoin and some do not since all value is subjective. The rationale for assigning value to bitcoin is as varied as the human fabric itself.
In this context, society can be defined as those mutual users willing to agree to a medium of exchange and a store of value. Since bitcoin, just as the Internet, recognizes no political boundaries, Krugman resists seeing the global monetary unit as something social. Krugman sees society only as a multitude of aggregated fiefdoms where he is the emperor's cherished tailor.
Though, just like the untainted child in the Hans Christian Andersen fairy tale, some of us are beginning to notice. It's not the illusion itself that so offends our sensibilities, but more the notion that a competitive illusion is not to be permitted. If a free market illusion voluntarily agreed to from the bottom up is so desperately feared, then the protectors of the State-sanctioned illusion must not have the most benevolent of motives in store for us plebeians.
I don't know about you, but I for one can stand up and exclaim: "the fiat emperor has no clothes!" What if more of us did?
| 4.755987 | 1.545108 | -4.278226 | 1.256712 | 4.792535 | -2.406119 | 1.675252 | 0.825466 |
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It includes the following municipalities: Valencia de Alcántara, Membrío, Salorino, Santiago de Alcántara, Cedillo, Herreruela, Herrera de Alcántara, Carbajo and San Vicente de Alcántara. It takes in the west of the central strip of Extremadura, between Portugal and the provinces of Cáceres and Badajoz.
Grassland is by far the most common habitat, a landscape transformed by man for millennia. It is home to an extraordinary range of species in danger of extinction such as the Spanish Imperial eagle, the black vulture, the Iberian lynx, the bobcat, the Iberian wolf, the golden eagle, short-toed eagle and the kite.
The largest and best preserved group of dolmens in Western Europe, declared of cultural interest in the category Megalithic Complex is found here. In addition, it also has several national landmarks like the Church of Rocamadour, and the Gothic Quarter, both in Valencia de Alcántara, and a large number of churches and hermitages of peculiar architecture.
The highlight here is definitely the natural environment, especially the Tagus International Park and Sierra de San Pedro.
Each place that is part of the Community has its own festivals and traditions such as carnivals, pilgrimages, Holy Week processions, etc. Prominent among them is Corpus Christi in San Vicente de Alcántara and the Pilgrimage of San Isidro in Valencia de Alcántara, both declared of Regional Tourist Interest, the Medieval Festival Boda Regia also from Valencia or the Mascarrá, held in various towns.
Many are the products and dishes that can be found in the area, Olive oil, cheeses, honey, sausages, el buche, a hearty sausage stew, tripe dishes, pancakes, fritters, Easter buns and almond biscuits.
In such a large area you can find many types of accommodation and eating options, just check their websites. The Tagus International Park has many signposted paths for hiking, mountain biking, etc. and the boat Balcón del Tajo does trips on the River Tagus.
Sources: Information extracted from www.mancomunidadsierrasanpedro.com, http://taejo.eu, www.barcodeltajo.com and Wikipedia.
| 4.756616 | 2.105961 | -2.064404 | 2.44269 | 3.955168 | -2.423546 | -2.09442 | 1.22513 |
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Explore Halifax and then set off to see the rest of Nova Scotia!
Have 7 days to spare? Here’s what you can do in Nova Scotia with a week to work with.
Wherever you go, stay in a small area. Don’t try and cover too much ground or you’ll spend most of your vacation on the road.
With several weeks on your hands you can add a few of these ideas together.
These itineraries assume you have your own car (travelling by bus or shuttle bus will take longer) and that you are starting and ending in Halifax.
See the famous Peggy’s Cove Lighthouse and some of the scenic fishing villages and coastal areas like Lunenburg and Mahone Bay. Go as far south as Liverpool, then cross Route 8 through Kejimikujik National Park to the artistic haven of Bear River and to Digby in the Annapolis Valley where you can feast on scallops. Continue down the Digby Neck penninsula to Brier Island, an area famous for its whale watching tours. On the return leg to Halifax, stop in the lively university town of Wolfville, and the Acadian historical site of Grand-Pre. In this area you can also try some of the province’s best wines.
Work your way up the rugged eastern shore on Highway 7, through Sheet Harbour and Sherbrooke Village (always popular with kids) and over the causeway at Canso onto Cape Breton Island. Take in the fantastic Alexander Graham Bell Museum in Baddeck before heading west to the Cabot Trail. From the end of the trail, head all the way to the eastern coast of the island for the Fortress of Louisbourg. Return to Halifax on the main highway, with a break to visit the celtic university town of Antigonish and see the Hector Heritage Quay in Pictou.
This one is for outdoor adventurers. Leave Halifax on Highway 102, heading for Truro. Your first stop is Shubenacadie, where you can go tidal bore rafting, a wild ride on the waves caused by this natural phenomenon. Kids will enjoy the nearby wildlife park too. At Truro, turn off the highway for Route 2 and the small towns of Five Islands and Parrsboro. Spend a couple days rockhounding, camping, learning about dinosaurs at the Fundy Geological Museum. Continue along the coast to Joggins, where you can see some of the world’s best fossil cliffs. From Amherst, return to Halifax on the main highway or, if time allows, take in some of the beautiful beaches around Pugwash and Tatamagouche on the northern shore.
| 4.759411 | 1.285859 | -3.434855 | 2.191998 | 5.265923 | -4.419753 | -4.741581 | 0.568217 |
15,578 |
A proof of English proficiency, IELTS score of 6.0 or TOEFL (IB) score of 80 or paper based TOEFL score of 500 is required.
At SQU, researcher will be a part of the largest civil and environmental engineering department in Oman and a vibrant research community. Researcher will have opportunity to interact with many faculties and researchers working on biofuel and environmental engineering across the academic departments and centers. In addition, Muscat is a fantastic place to live with low living expenses.
Tax free financial benefits will be awarded as 22,200 USD/year (8400 OMR/year) plus full tuition fee waiver. Free medical coverage will be provided at university clinic and at hospital. A priority based housing facility is also available near to the university campus by 120 OMR/month.
Applicants should send a cover letter, detailed CV (with names and contact information for two references), and samples of applicant’s recently published journal article to Dr. Muhammed Abdullah Al-Mamun, Email: [email protected]; [email protected]. The appointment will begin in Sep 2017 or as soon as the position is filled. Application date line is 30th June 2017.
| -4.336732 | 0.713489 | -6.771163 | 1.183884 | 4.619021 | -6.284296 | -4.728818 | -0.458034 |
40,404 |
MTE sources Black Spruce lumber using sustainable forest planning. Our forestry within the Menominee Forest keeps the Black Spruce population at a healthy level, while maintaining a large supply of Black Spruce lumber for sale.
Black Spruce is usually a rich white color with occasional hints of yellow. It boasts a fine, even texture and consistently straight grain. The wood is very easy to work with, and it glues and finishes well. Due to its pore structure, a sanding sealer, gel stain or toner is recommended rather than a classic stain.
MTE is a great source for responsibly harvested aspen wood – Contact us today to place an order.
| -3.523673 | 1.016452 | -4.051806 | 1.603082 | 4.766165 | -2.305931 | 1.638721 | 0.572431 |
99,602 |
CADILLAC — Gopherwood Concerts brings something new to Cadillac’s Elks building, third floor, with world music from India and the Americas with Sumkali at 8 p.m. on Jan. 13.
Sumkali is a diverse group made up of musicians from North and South India and the American Midwest. Through their diverse backgrounds they have been able to craft music with a global appeal that goes beyond just fusing genres together.
Their music is a thrilling meld of Indian classical music, Bollywood, American jazz, folk, funk and Motown. They have recorded four albums, including their 2015 release “Tihai” which earned them two nominations for “Outstanding World Music Album” and “People’s Choice Award” at the Detroit Music Awards in 2016.
Based in Ann Arbor, Sumkali has been performing for over 10 years and have been lauded as one of the Midwest’s premier World Music groups.
“Sumkali plays fusion that works. Their music is a thrilling meld of Indian classical music, American jazz and more,” said San Slomovits, founder of award winning music group Gemini.
Advance tickets are at a cost for adults, for students and free for children 12-years and under (with an adult). You can get your ticket at the After 26 Depot, Toy Town in Cadillac, online at My North Tickets or by calling (800) 836-0717.
Jen Sygit (house concert) on May 12.
Gopherwood Concerts is a small nonprofit group located in Cadillac, whose goal is to bring quality musical entertainment to everyone in the area. For more information about this show, call (231)846-8383 or visit the Gopherwood Website at gopherwoodconcerts.org.
Gopherwood concerts is affiliated with and funded by the Cadillac Arts Council.
| 1.034755 | 1.069076 | -3.20116 | 1.624754 | 5.785155 | -3.892608 | -4.775371 | 0.302794 |
51,521 |
Over the past year, the public’s economic mood has darkened considerably, with 86% of individuals now reporting that the U.S. economy is headed in the wrong direction, up from 64% just one year ago, according to a new study by MetLife. More than nine in ten individuals (93%) believe that Americans have to work as hard as or harder than ever just to get by, up from 87%. Yet, an intriguing dichotomy is emerging. Despite this collective pessimism about the outlook for the country, the American spirit of personal optimism and self-reliance is holding strong; 85% of individuals expect their own financial situation to be about the same or even better this year, compared to last year.
This is a key finding from MetLife’s second Study of the American Dream, which reveals that the American dream is still alive despite growing concerns about rising energy costs, declining home values and rising levels of personal debt. More than one-third (37%) of the individuals surveyed believe they have achieved the American dream – which a majority define first and foremost as “financial security.” Over the past year, there has been a significant increase in the number of Baby Boomers who report that they have achieved the dream – up 8 percentage points to 40%. Among Americans who have yet to achieve it, 74% believe that it’s possible to achieve the American dream in their lifetime, up from 67% last year.
Despite such personal optimism, Americans are deeply concerned on a collective level about the country’s economic outlook. Across generations, roughly half (49%) of Americans expect the economy to be worse in 2008 than it was in 2007. Causing particular uneasiness are energy costs – cited by 58% of Americans as a reason the economy is off track, up from 41% last year – as well as healthcare costs (36%), the national budget deficit (31%), high personal debt levels (30%) and the outlook for Social Security (25%). Ninety-three percent are concerned that rising energy prices will have a negative impact on the American dream over the next 5 - 10 years.
Consistent with last year’s finding, roughly two-thirds (64%) of Americans feel pressure as a result of diminished confidence in government-sponsored benefits. An equal percentage is frustrated by shrinking employer-sponsored benefits, which – due to competitive and cost pressures – are increasingly shifting to the individual. Slightly more than half of Americans (52%) believe that they are carrying more financial burdens for their family than their parents’ generation had to. Nearly three-quarters (72%) of Americans are worried that the financial burden shift will lessen future generations’ (such as their children’s) ability to lead a comfortable life. Seventy-four percent of Generation Y workers (18-31 year olds) feel that the bar is constantly rising in terms of satisfying the basic necessities of life, compared with 65% of workers overall.
There are several indicators that Americans are gearing up to protect their own financial futures: 1) their interest in creating their own personal safety net, 2) their desire for their employer to provide employee benefits and advice at the workplace, and 3) their level of engagement with the 2008 Presidential election.
In light of uncertainty about traditional social and corporate safety nets, more than three-quarters (77%) of Americans say they are planning to build their own personal safety nets to protect their family’s financial future. Yet, the products that they think should comprise a personal financial safety net differ by generational cohort. While both Baby Boomers and GenYers are first and foremost interested in health insurance that continues through retirement (64% and 57%, respectively), followed by a retirement savings plan such as a 401(k) (49% and 52% respectively), Boomers rank income annuities (45%) and long-term care insurance (31%) next; whereas, GenYers would include life insurance (38%) followed by income annuities (31%) in their personal safety net.
There is an important role that employers can play in helping individuals create their own safety net: providing access to employee benefits – even if employees have to fund most or all of the costs themselves. Across generations, 95% of individuals believe employee-funded benefits are important. Younger employees, in particular, are also looking for benefits education and advice. More than one in four (26%) would like more education from their employers about the products they should purchase to create their own personal financial safety nets and one in five workers would like financial planning in the workplace to help them make sound decisions.
Finally, Americans are preparing to take political action to keep the American dream within reach. Three in four Americans believe that the 2008 Presidential election will be more important than past elections – and roughly the same percentage (71%) believe the election’s outcome may impact their ability to achieve the dream. Gen Xers and GenYers are eyeing the election particularly closely, with 75% of each demographic saying the election’s results will impact their ability to achieve the American dream.
The most important election issues cited by Americans are the economy (26%), the war in Iraq (17%) and healthcare (12%). While members of the Silent Generation are most concerned about the War in Iraq, 80% of all Americans – and 86% of GenYers – are concerned that ongoing conflict in Iraq will compromise their ability to achieve the American dream.
From January 4-6, 2008, Strategy First Partners and Penn, Schoen and Berland Associates conducted 800 online surveys in the United States among the general population, including the Silent Generation, Baby Boomers, Generation X and Generation Y. The purpose of the study is to understand and track Americans’ sense of financial security and their ability to achieve the American Dream.
*Only those 18 and older in the Generation Y cohort were interviewed for the study.
| 4.656605 | 2.391982 | -0.193612 | 2.112839 | 6.076909 | -1.60683 | 2.119382 | 1.689911 |
56,687 |
My experience at the IBM developer day 2019 conference. This is the highlights of the event that covers the latest technologies in AI, Cloud and Blockchain.
IBM code day 2018 was a demonstration of IBM’s capabilities in delivering a platform that uses the most latest Technologies.
| -5.055441 | 0.768663 | -11.512482 | 1.450124 | 1.746498 | -6.301916 | -4.771423 | -0.750931 |
51,676 |
The apostle John is really a man for our times. He wrote his three New Testament letters in a bold, direct, even dogmatic mannermore so perhaps than any other New Testament writer. Although renowned traditionally as the apostle of love (and he was), he was an authoritative, uncompromising teacheran exclusive-style instructor with a crucial message of truth versus error, which the church much needs to hear in the twenty-first century.
This commentary considers Johns clear, simple, unambiguous words from his three brief but profound letters. His themes, some of them reiterated more than once, emerge powerfullysuch as the first letters stress on doctrinal certainty, moral clarity, and the preeminence of biblical love, along with the second letters emphasis on living the truth and the thirds on discerning friends and foes in the local church.
1, 2, 3 John : MacArthur New Testament Commentary by John MacArthur was published by Moody in March 2007 and is our 30751st best seller. The ISBN for 1, 2, 3 John : MacArthur New Testament Commentary is 9780802407726.
Be the first to review 1, 2, 3 John : MacArthur New Testament Commentary!
Got a question? No problem! Just click here to ask us about 1, 2, 3 John : MacArthur New Testament Commentary.
| 4.726426 | 1.271309 | -6.472276 | 1.841604 | 4.109383 | -1.070655 | 3.229242 | 0.9302 |
45,050 |
The third part of the Regal Worm trilogy, Pig Views, hit the streets on July 13, 2018. For this installment Jarrod Gosling used a more song-based format and delivers nine songs, with two bonus songs on the pink vinyl double LP version. There are a number of strangely named songs such as “Rose Rubus Simlax Vulcan,” “Revealed as a True Future Tyrant,” “Rose Parkington They Would Not Let You Leave,” “Jag Vet,” “The Dreaded Lurg,” “Huge Machine You Are So Heavy,” and the bonus track “The Evil Eye Is Liquified.” All eleven songs feature Mellotron either in the background or as lead. The longer songs allow Jarrod to explore heavy psychedelic grooves, tempo changes, and mood shifts, with a mixture of bluesy jazz and Canterbury sound. I’m not clear how the album title Pig Views relates to the music, but the engaging songs take you on a variety of musical journeys. Chanted song titles, sounds of children playing, tasty sax riffing, female vocal harmonies, mournful organ, scratchy 78 rpm effects, poetic narrations, and reversed tapes enhance the songs. Some of the high points for me are the 15 minute song “The Dreaded Lurg,” with its shifting moods; the short 59 seconds of “Butterfly” with its vintage 20s jitterbug, poetic narration, and 78 rpm vibe; and the introspective “Huge Machine You Are So Heavy.” Quite a nice album with the bonus tracks engineered by the legendary Sean Magee (Rush, Beatles, Rolling Stones, etc.).
Surely every progressive rock fan in the world has been paying attention to Regal Worm by now. If they aren’t, it’s time to start. Pig Views continues the amazing run of Jarrod Gosling producing unpredictable, complex music that draws from classic progressive rock but sounds neither deviravative nor stuffy. He has a way of bringing together some of the best aspects of 70s music in a fresh way that is both instantly engaging and worthy of repeated listening. Although the arrangements overall are dominated by keyboards, the album’s first track, “Rose Rubus Smilax Vulcan,” starts out with a delicate acoustic guitar part and a lovely vocal melody that works into a surprising section featuring Latin (or pseudo-Latin) chanting kind of like Orff’s Carmina Burana crossed with the chanting section of “The Ancient” off of Tales from Topographic Oceans. Every track features its own unique qualities, like the harp in “Rose Parkington They Would Not Let You Leave” or the double-Mellotron melody (flute and strings) at the beginning of “Pre-Columbian Worry Song.” Pig Views features only one multi-part epic track, “The Dreaded Lurg,” which covers many moods and sounds over a bit less than 15 minutes. In the midst of all of the vintage keyboards, saxophones features prominently in several tracks, providing both chordal punctuation and lead lines. Sometimes keyboard-heavy arrangements can sound lightweight, with less sonic impact than music with more prominent guitar, but Gosling manages to give his instruments real heft, partly by density (such as the doubled Mellotron parts I mentioned), and partly bringing in other sounds like the saxes and the occasional guitar. In addition, the bass guitar is often presented high in the mix with a gritty tone. The production is also an important factor, imparting the illusion of a full band playing rather than one musician doing the majority and only a few guests. When it comes to progressive rock in 2018, one of the finest bands going isn’t even really a band, but from listening you might not know that, and it doesn’t matter when the result is this good.
| -3.383665 | 1.060888 | -3.225522 | 1.048062 | 5.49967 | -2.346509 | -2.508288 | 0.246167 |
41,668 |
In the opening narration to the final mission of Call of Duty: Ghosts, David Walker says the following of his father: "Dad taught us many things, but one lesson always stood out. Good men are defined by the choices they make." That line feels like a slap in the face from a game that forgets the step forward that Black Ops 2 dared to take and just focuses on a painfully linear experience entirely devoid of choice. It doesn't even try to use that linearity to its advantage, like the first two Modern Warfare games did (at times). Above all, Call of Duty: Ghosts feels lazy.
| 4.767082 | 1.011157 | -3.946398 | 0.324157 | 5.749631 | 1.901273 | 1.071832 | 0.660239 |
33,130 |
SAN FRANCISCO – Oct 26, 2015 – Established in 2013, US subsidiary of Adways Inc. (Head Office: Shinjuku-Tokyo, CEO: Haruhisa Okamura), Adways Interactive (Head Office: San Francisco, CEO: Ken Asakura) today announced the full launch of PreLaunch.me, releasing the Android app out of Beta with new features and debuting the PreLaunch.me web app for iOS and Android, available for publishers and gamers in the US, Canada, Australia and UK. To download PreLaunch.me to your Android device, visit Google Play, while iOS users may visit www.PreLaunch.me via the Safari web browser.
PreLaunch.me is a wholly-owned subsidiary of Adways Inc., the leading mobile advertising technology company based in Japan that is publicly traded on the Tokyo Stock Exchange (Code 2489). Its US office was established in 2013 and is located in San Francisco, CA. For more information about PreLaunch.me, please visit https://prelaunch.me/.
Subsidiary of Adways, a publicly operated digital marketing company headquartered in Tokyo. Adways runs AppDriver, the largest CPI ad network in Japan and works with the likes of Gree, DeNA, Square Enix and Facebook. Adways Interactive is a mobile marketing agency based in San Francisco.
| -4.243328 | 0.862411 | -11.114396 | 0.202654 | 3.221093 | -7.436314 | -4.776879 | -1.066603 |
41,114 |
Home » Cooking » Success Finally!
I was able to produce 48 pieces of edible chocolates. My brother taught me an “only fools can mess this up” type of dessert and I was able to successfully execute the recipe last weekend.
I will start experimenting with the variants in the coming weeks with my loyal friends and family as guinea pigs. My younger sister also came up with a catchy name for my concoctions – Chrissy’s Crispies.
1. Just buy chocolate bars from the specialty stores (one bar costs about 70-75 pesos each) and each big bar can produce up to 25 pieces (1 ounce each piece).
2. Melt the chocolate bars under low heat or do the double broiler method.
3. After the bar has melted, mix the rice crispies. How much rice crispies you will put depends on how much you want in your chocolates.
4. Pour the mixture over the baking cups and wait for it to harden up.
| 4.375289 | 1.015131 | -5.819405 | 1.586609 | 4.491309 | -3.895954 | 3.168721 | 0.645128 |
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Welcome to “52 Treats I Can Eat!” As a brief introduction, I can’t say that I have always been a cook or even had a profound interest in cooking and baking. In fact, I still don’t think I can claim being a good cook, but hopefully we can all grow together in this process! When my husband, Stephen, and I were first given the diagnosis that our son had a milk, egg, nut and sweet potato allergy we did what most parents do. We questioned why, how and what in the world we were going to do now that we had to completely alter our diets and prepare to feed a child with many dietary restrictions. It isn’t as easy as just removing a few jars of peanut butter from the pantry and feeding our child rice or soy milk rather than cow’s milk. Grocery shopping became more tedious and detailed than I ever imagined it could be. Eating out at restaurants now warrants talks with the chef, and reading not only a dinner menu, but an allergy free menu, as well.
More and more children are being born these days with food allergies and intolerances and it saddens me beyond belief. One thing I have learned since the food allergy diagnoses is that the food allergic community is one of the most supportive and understanding communities around! Since the diagnosis two years ago, I have felt compelled to do SOMETHING. I didn’t know what that something was, but I have prayed about it and thought long and hard about how I could make a difference in someone’s life who was going through a similar experience with their child or a loved one who has been diagnosed with a food allergy. As I talked to a good friend today over lunch, it hit me. I wanted to start a blog. (You have to start small, right?) We tossed ideas around and came up with the idea of “52 Treats I Can Eat” in an effort for me to try new recipes that are allergy safe AND taste good. Let’s face it. If you have made any attempts at cooking allergy free, chances are that you have made some “treats” that taste more like cardboard than cookies. I want to use this blog to account for the new recipes that I try, along with reviews from Caleb as “Do it again, Mommy!” or “That’s Yucky!” (We will all keep our fingers crossed that we get more yummy reviews than yucky!) I have many go-to recipes already, and I will also highlight them and point you to my favorite sites and blogs along the way. I will also list some quick pre-packaged foods for when you are in a rush and need to make a quick run to the grocery store. In fact, there is a running tab up at the top of the home page where you can find this list. Many items were what I turned to when we first found out about the allergies in our family and I hope that those of you with a recent diagnosis can also find the list helpful.
This entry was posted in Allergy Cooking, Uncategorized and tagged baking, cooking, food allergy. Bookmark the permalink.
I look forward to seeing all 52 treats! My little boy is also milk, egg and nut allergic so I loooooove finding new recipes for all of us to eat. I’ve added your blog to my blogroll too. Yay!
Thanks Lana! I think I am really going to enjoy this project! Thanks for adding me!
| 4.719111 | 1.088987 | -4.626147 | 1.593286 | 6.200357 | -6.300582 | 1.675019 | 0.560265 |
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Here are this weeks deals at Target! Remember that at Target you can "Stack" manufacturers and store coupons on the same item. Be sure to go to Target.com and print your target coupons. Also, sign up for Targets Text Alerts to get great coupons sent right to your phone!
FREE Zantac Sample! HURRY! Won't Last!
This one was gone way too fast the last time it went up. Hurry up and get your FREE sample of Zantac!
Available in e-book format also!
Share Your Opinion, Get Paid!
i-Say is a community of dedicated individuals comprised of hundreds of thousands of people all interested in achieving one goal - sharing their opinions. i-Say panel members take surveys, create polls and help shape the products and services we all use every day.
Dr Seuss up tp 70% Off!
Get Dr. Seuss up to 70% off at Totsy!
Make your little one a resident of Seussville in quirky and adorable clothing from Dr. Seuss. With characters taken right out of the classic children's books, this selection of bodysuits, long underwear and hoodies will delight your little Dr. Seuss fans. Fits infant and toddler.
Not Too Early for Christmas! HURRY!
Need Back To School Clothes?
Turn Your Summer Pictures into Canvas!
Now that Summer is almost over, I am sure you have lots of great summer family pictures that are just stored on your memory card or hard drive. Why not turn one into a beautiful canvas print for FREE! I have gotten 2 so far and love the quality! These make great gifts as well! Go through Canvas People and get a FREE 8x10 Photo Canvas or $50 towards any size canvas!
FREE Oikos Greek Yogurt Sunday!
Don't throw away your paper, look on the last page of Parade magazine inside your Sunday paper for FREE Dannon Oikos Greek Yogurt (up to $3 value). I have found that about every other Parade mag has the coupons in them. So if your buying a paper at a store or box, make sure to check the Parade mag for the coupon before buying the paper for that coupon.
Thanks Mojo Savings for the tip!
Free Samples For Women Selected by Women!
Account and you can cash it out when you get $5 saved up!
Here is a look at this weeks best deals at Rite Aid. Be sure to watch your Video Values for August and print your coupons!
Here is a look at this weeks deals at Walgreens. There are quite a few good deals this week and a great scenario to help you get the most out of this week!
Get Your $2 Puppy Chow Printable Coupon! HURRY!
I am a Mom and have looked forward to school starting all summer! Being a Work From Home Mom, it is hard to work on my website and keep up with a 5 year old. Now that school has started, I actually have some time to myself again! I found a great website for Moms called CafeMom which is filled with great information, great advice and a great way to meet other moms who share the same interests. Check it out here!
If you are not a Swagbucks user, you should definitely give it a try!
**It is MEGA Swagbucks Friday! That means you have a better chance at getting high value Swagbucks for your searches!
You can also earn Swagbucks through special Swag Codes that are hidden online.
Shop in the Swagstore! You can redeem your swagbucks for all kinds of neat things! The gift $5 card for Amazon are the best value costing only 450 Swagbucks!
Here is a look at the CVS deals 8/21 - 8/27. I could not find anything free this week but there are some good deals. If you have rainchecks, this week would be a great week to use them. Remember to scan your CVS card at the red coupon machine in the store so you can get your CVS coupons! Visit the coupon center this week for a $3 off Any $15 stomach remedy purchase. Also, don't forget to get and use your Green Bag Tag!
Extreme Measures - Newspaper Theft on the Rise!
My Coupon Friend, Nathan Engles from We Use Coupons, was interviewed for USA Today. Please take a moment and read this article here. The article is about how newspaper theft is on the rise. Nathan is an example that you don't have to steal to get great deals!
My favorite quote from Nathan was "It looks like a meaningless little piece of paper," he says, "but it's changed my life in ways I could have never imagined."
I have found that organized couponing is essential to saving money at the stores. In order to really make the most of your couponing, you need to have a way to organize your coupons. I use a binder system. I use a Case-it binder with a carrying strap and 9 slot baseball card sheets to put my coupons in. I have found a few places that you can get starter kits and other items to help get organized. I have also found a few great resources for purchasing newspaper insert coupons and full inserts.
Get In On The Daily Deals!
There are a lot of daily deal websites popping up. It is best to take advantage of these websites and sign up for your daily e-mail for each one. You will be surprised at how many great deals are out there on a daily basis! If you don't have e-mail notification, then you may miss out. I have scored movie tickets, concert tickets, free movie rentals, and more by using these daily deal websites. Although, they may not have a location where you live, choose the closest. You will find that there are a lot of online deals that are good anywhere or for major retailers that are available anywhere.
Winn-Dixie Stores, Inc. (NASDAQ: WINN), today announced that flu vaccinations are now available in all Winn-Dixie in-store pharmacies to help prepare guests for the upcoming flu season. Guests will receive the flu vaccine for the discounted rate of $24.99 when purchased using their Winn-Dixie Customer Reward Card.
*HOT* $0.75 Waverly Printable Coupon!
Hurry up and print your $0.75/1 Waverly Printable Coupon here before it hits the print limit! This one will not last long!
Here is this week's top 5 Deals at Publix. Publix sales in the metro Atlanta area run Thursday-Wednesday, with all other Publix stores running Wednesday-Tuesday sales. Publix doubles coupons of .50 cents or less everyday. There are no limits on how coupons Publix will double in one transaction. Publix accepts competitor coupons! Please ask your store's customer service desk who they consider to be competitors. Mine are Kroger, Super Target and Food Lion. You can combine 1 manufacturers coupon with 1 Publix coupon OR competitor store coupon on the same item. Publix offers a Mystery Coupon Item or a Penny Coupon Item on Wednesdays & Thursdays depending on when your ad comes out. This item is available for .01 cent with a minimum purchase of $10 AFTER coupons. Some stores require the coupon paper ad, some do not. Please ask for details at your store!
Here are this weeks top deals at Food Lion. Food Lion allows up to 10 "like" coupons per shopping trip. Be sure to sign up for Food Lion e-mails so you will get FLIPs (Food Lion Internet Printables). Also, be sure to check out the e-coupons that are available on the Food Lion website. You cannot "Stack" coupons at Food Lion. That means you can only use 1 coupon per item. That means that you have to choose one or the other.
Lowe's Foods doubles coupons every day up to $0.99 Value. They double 20 coupons per day. Read more about their policy here.
Here is this weeks deals at Harris Teeter. After a long week of Super Doubles, I was ready for a break. However, this weeks looks great so I will be making a trip back to Harris Teeter tomorrow! Harris Teeter doubles coupons every day up to $0.99 value. They have a limit of 20 coupons doubled per day with a limit of 3 "Like" coupons/items. They also limit printable coupons to 2 identical per day.
Here are this weeks deals at Bi-Lo. Remember that the new coupon policy states that you can use "Competitor" coupons and stack "Store" and "Manufacturer" coupons on the same item. They will also double up to $0.60 (some stores double up to $0.99) everyday. They also have a limit of 10 "Like" coupons per trip.
Right now you can get a $30 Totsy voucher for only $15 at BuyWithMe! Totsy always has some AMAZING deals - I have purchased from them several times!
*HOT* $1 off Skittles, Starburst or Lifesavers Bag!
This HOT coupon is back!! This $1 off any one Skittles, Starburst or Gummy Lifesavers bag coupon should get you some super inepensive candy to curb that sweet tooth! Right now both the Skittles and Starburst are only $1.50 at my Kroger store so guess what I’ll be snacking on tonight? HURRY because this never lasts long!!
*HOT* $1 off ANY Minute Maid 10 Pack!
There is a new coupon available on Coupons.com for $1 off ANY Minute Maid 10 Pack Juice drinks! If you have a Harris Teeter nearby, they have the Minute Maid Water Beverage 10 pack for $2.79. Use the $1 coupon doubled and get it for only $0.79!!!
I have not seen any Minute Maid juice box coupons in the past so this is a great RARE coupon! Print it HERE before it is gone!!!
*HOT* Win a Memory Foam Luxury Bath Mat Back To School Giveaway!
Make stepping out of a bath or shower just as refreshing as stepping in with this best-selling bath mat. The Microdry fabric top is super soft and absorbs water twice as fast as other materials to keep you dry and cozy. The generous ½" memory foam fill cradles your feet to offer ultimate feel-good cushioning. A slip-resistant base grips a dry bathroom floor firmly for your safety.
I was given a fabulous opportunity to try out and review the bath mat and our whole family loves it! I immediately put it in our bathroom and started trying it out right away. It is so incredibly soft and luxurious! I find myself standing on the mat every time I go into the bathroom because it feels so good! And the fact that it is slip resistant and absorbs moisture are added bonuses! It lives up to it's claims! If you are looking for a great wedding gift, Christmas gift or even a gift to yourself, this is worth it! You can find these at Bed Bath and Beyond!
*Disclosure: MindsInSync Inc. (representing Microdry) has offered to sponsor this giveaway. No compensation was received for this post.
*HOT* Hallmark's Confidence Care Package Back To School Giveaway!
A big thanks to Hallmark for sponsoring this awesome prize for the Back To School Giveaway!
I was given the opportunity to review the Confidence Care Package and love it! The Hallmark cards are a great way to show care and love. My youngest loves the ladybug case and thinks the note cards are sweet! And my husband recorded the book and my youngest loves it!
With backpacks full of new pencils, binders and glue, kids might think they’re ready to take on the first day of school. But, sometimes kids need more than school supplies to face the exciting and challenging situations the upcoming year holds. That’s why Hallmark has created a back-to-school confidence checklist!
Let them hold onto your words. Kids often get embarrassed when parents say “I love you” in front of their friends. Think about sticking a card in their backpack or inside a textbook, so they can find it later and hold onto it all day.
Surprise your child with a lunchtime delight. Fruits and veggies will help a kid be physically fit, but don’t forget about a child’s emotional wellness. The unexpected “I love you” or “good luck” will let your child know you’re by their side, even after they get on the school bus.
Pass the encouragement bug around your family. Challenge the entire family to support each other by passing around the encouragement bug — Hallmark’s Bug ‘Em. One person starts by filling Bug ‘Em with treats, a coupon to do something nice (e.g., make their sibling’s bed) or a kind note of encouragement, and then leaves Bug ‘Em where the recipient will find it. Once the recipient finds Bug ‘Em, he or she is charged with surprising another family member and spreading the encouragement bug.
We have done the homework for you and want to give you a jumpstart on the school year.
*BONUS* Hallmark Recordable Storybook - Recordable Storybooks allow you to record your voice, and your little ones can read along with you even if you’re far away. They are also great for encouraging your kids to read and building confidence for reading aloud!
Print your Quiznos coupons before they are gone!
Decoding Coupon Barcodes - Is It Wrong?
I was shopping in Harris Teeter yesterday and ran into an interesting situation. Because I am often recognized at the stores, people always ask me questions. I am more than happy to help. However, when I have to tell someone their doing something "Wrong" I feel bad. I had to deal with that yesterday.
First of all, I was asked if there was a way to read the coupon bar code to see if they can use it on other products than what it was intended for. I answered "No, I don't teach that practice". Then I was informed that a customer in the store told them about it and was doing it regularly. I was a little upset about this. Practices like that is the reason stores are tightening up their coupon policies and making it harder for us to get great deals.
Simply put, it is deciphering the bar code on a coupon to see if it will work on different (preferably less expensive) items.
Look at coupon barcode decoding this way: It is like using counterfeit money to pay for your purchase! Although the cashier may not notice you are paying with a counterfeit bill, it will eventually reveal itself and the store looses out. A coupon is a form of payment and by not getting what the coupon says it is for is the same as paying with counterfeit money.
So, please read your coupons, get exactly what it says it is for and follow the parameters given by the coupon. Please don't use the barcode to determine what you can get because you know the register won't beep. Just because the register does not beep, does not mean that it is OK.
There are plenty of other websites and blogs that teach this practice and believe that it is OK. Please Be Aware! They believe they are right and have no problem teaching others to do the same. Taking advantage of a glitch in the bar code to get around the text of the coupon is fraud.
| 3.715848 | 0.530093 | -5.008596 | 0.944506 | 0.527988 | -4.483736 | -4.761282 | -0.272727 |
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1) Indivisible NJ4 January working member meeting tomorrow, Wed. Jan. 17, 7PM at the Monmouth County Library Branch in Holmdel (in the BellWorks Complex at 101 Crawfords Corner Road). Join one of our subgroups and help to unseat Smith in 2018!
2) Register in the link below for our three Meet the Candidate Night series of discussions. The first event is coming up on Jan. 25 with Jim Keady.
CALL TOPIC: On January 19, Congress will vote on another “must-pass” bill to fund the government. This bill requires at least eight Democratic senators to vote yes, giving Democrats crucial leverage—AGAIN. That means we have another opportunity to stand up for the most vulnerable among us: immigrants at risk of deportation, children, and communities rebuilding after natural disasters.
Caller: I am calling to express my support for the DREAM Act and the hundreds of thousands of Dreamers whose lives are on the line. I ask that you ensure that a clean DREAM Act is included in the upcoming budget resolution to fund the government and that you vote AGAINST any proposal that does not include a clean DREAM Act. The RAC bill the Congressman sponsored is too restrictive and partisan. Any funding for a divisive border wall should be removed.
I also ask that the Congressman use this opportunity to secure funding for CHIP as well as real relief for Puerto Rico and the U.S. Virgin Islands. These funding needs have been unmet for far too long, and millions of people are suffering as a result.
Will the Congressman commit to voting against the January 19 funding bill (continuing resolution or CR) if it does not include the DREAM Act, funding for CHIP, and disaster relief for Puerto Rico and the U.S. Virgin Islands and removal of funding for an atrocious border wall?
Caller: I am calling to express my support for the DREAM Act and the hundreds of thousands of Dreamers whose lives are on the line. I ask that you ensure that a clean DREAM Act is included in the upcoming budget resolution to fund the government and that you vote AGAINST any proposal that does not include a clean DREAM Act. Any funding for a divisive border wall should be removed.
I also ask that the Senator use this opportunity to secure funding for CHIP as well as real relief for Puerto Rico and the U.S. Virgin Islands. These funding needs have been unmet for far too long, and millions of people are suffering as a result.
Will the Senator commit to voting against the January 19 funding bill (continuing resolution or CR) if it does not include the DREAM Act, funding for CHIP, and disaster relief for Puerto Rico and the U.S. Virgin Islands and removal of funding for an atrocious border wall?
| 4.186015 | 0.758808 | -7.058328 | 0.842483 | -2.750676 | -3.684993 | -4.770431 | -0.381826 |
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Make a statement that no one can ignore! The PRETTY GIRLS SWEAT® Logo Tote will grab the attention of all who see it at the grocery store, farmer's market, gym class, the recreation center, or on the street. Stylish and durable, the PRETTY GIRLS SWEAT® Logo Tote bottom offers plenty of room to spare for a load of groceries or gear. DIMENSIONS: 13" x 20" x 8"
Exclusive PRETTY GIRLS SWEAT® merchandise. Limited quantity.
| 2.289519 | 0.058953 | -6.527965 | 0.063364 | 4.030876 | -9.233653 | -4.772439 | -0.997719 |
36,682 |
The Seattle Mariners announced tonight that they have swung a deal for infielder Ryon Healy from the Oakland Athletics in exchange for right-handed pitcher Emilio Pagan and infielder Alexander Campos. Of course, Mariners’ general manager Jerry Dipoto is the first one to make a move this offseason.
Healy will likely slot into the Mariners’ lineup as their first baseman, as his defense over at third base was quite questionable. In 260 innings at third base in Oakland during the 2017 campaign, the 25-year-old sported a DRS of -2, opposed to a DRS of 1 in 307.1 innings at first base.
Despite Healy’s breakout 2017 season, his time with the A’s was numbered, especially with the big rookie season that Matt Olson turned in, along with a quality rookie campaign that Matt Chapman turned in at the hot corner. Olson slashed .259/.352/.651 with an OPS of 1.003, along with 24 home runs in just 59 games, as Chapman had an OPS of .785 in 84 games in 2017.
Both of the young talents were ultimately blocking Healy. Healy mostly was the team’s designated hitter, but with the declining ability of Khris Davis in the outfield — though his power bat that had 42 home runs in 2016 and 43 home runs in 2017 — it’s been looking like Oakland would want to move him to DH.
In 149 games in 2017, Healy posted a slash line of .271/.302/.451 with 25 home runs, 29 doubles and 78 runs batted in. He’s not arbitration-eligible until 2020 and he won’t be a free agent until 2023, so the Mariners are acquiring five years of team control.
Pagan, 26, made his big league debut with the Mariners in 2017, as he pitched 34 games out of their bullpen. In 50.1 innings pitched, he had a 3.22 ERA, along with a 56/8 K/BB ratio and a WHIP of 0.934.
Campos, who was ranked as the No. 15 prospect in the Mariners’ system, doesn’t turn 18 years old until February 20. In his first season of professional ball, he managed to slash .290/.413/.367 with two home runs, 10 doubles and 26 runs batted in across 59 games with Seattle’s Dominican Summer League squad.
| -3.422781 | 0.847406 | -7.086974 | 0.281162 | 6.252743 | -4.704698 | -4.781911 | -0.539058 |
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Democratic candidate Dan Donahue, the 26-year-old ex-staffer for Mayor Joe Petty, scored a unanimous decision in Tuesday's special election for state rep in the 16th Worcester District, winning all 11 precincts and besting Republican upstart Carol Claros, 1,606 votes to 910. The victory earns him at least a one-year trip to Beacon Hill. Donahue, who won 63 percent of the vote to Claros' 34, will fill the seat left vacant when former state Rep. John Fresolo resigned earlier this year. The term expires in November 2014.
The outcome produced a study in contrasts at the post-election gatherings for both candidates. Inside City Lights on Grafton Street, a large crowd that included city and state officials and a host of friends and relatives and other supporters, there was loud banter, laughter and plenty of congratulatory hugs and handshakes. Claros, meanwhile, walked into Nuovo restaurant on Shrewsbury Street to relative silence about a half hour after polls closed. By then, the Donahue camp was already claiming victory. Claros waited until receiving the official results before thanking supporters - including her "secret weapon," daughter Giselle - and promising "This is not the last time you'll see me running for anything."
The other contrast came in the immediate future plans for the two political rivals. While Donahue, 26, will hit the streets, literally, to do some "Thank You" greetings Wednesday, Sept. 11, the 30-year-old Claros plans to take a jog, buy her daughter a new pair of shoes (Donahue, too, may be buying a new pair - he says he wore through two pairs on the campaign trail) and maybe even start making use of her gym membership again.
As for their political futures, Donahue fist must be sworn in, something one House lawmaker says could happen toward the end of the month or in the first week of October (there were two other special elections in the state -Carole Fiola was victorious in Fall River and former House aide Dan Cullinane won in Dorchester - and all three winners could be sworn in at once). Claros, meanwhile, had barely finished her concession speech when she was being pushed to run for state Senate against Michael Moore next year. Her campaign manager, Jim Knowlton, hinted at a possible run for School Committee in two years.
Claros says she is not immediately certain what she'll run for next. Right now, she wants to help start a Republican Ward Committee. "I'm just thinking of getting back to a normal routine with my daughter," says Claros. "I want to build support for our neighborhood."
Donahue, in the meantime, gets set to join House lawmakers on Beacon Hill and says he is ready to get started. "I have great experience working with neighborhood organizations like CDCs [Community Development Corporation], the city manager's office and the mayor's office," he says. "The biggest thing is I know this district. I want to make sure Beacon Hill is paying attention to this district."
| 4.764357 | 0.882267 | -5.026688 | 0.340369 | 5.081127 | -5.778473 | -4.788015 | -0.275685 |
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One News Page > News Videos > Julian Assange > Trump says Wikileaks is "not my thing"
Trump says Wikileaks is "not my thing"
U.S. President Donald Trump said on Thursday he did not have an opinion about the arrest of Wikileaks founder Julian Assange, who faces the prospect of extradition to the United States over the publishing of secret official information.
ROUGH CUT (NO REPORTER NARRATION) U.S. President Donald Trump said on Thursday he did not have an opinion about the arrest of WikiLeaks founder Julian Assange, who faces the prospect of extradition to the United States over the publishing of secret official information.
British police arrested Assange on Thursday after Ecuador withdrew its asylum that had allowed him to take refuge in the country's embassy in London for seven years.
"I know nothing about WikiLeaks.
... I don't really have any opinion," Trump said to reporters before a meeting with South Korean leader Moon Jae-in.
On the campaign trail during the 2016 presidential election, Trump repeatedly praised WikiLeaks.
Shortly before the election, Trump said, "I love WikiLeaks," after it released a cache of hacked Democratic Party emails that harmed the candidacy of his opponent, Hillary Clinton.
Manning was convicted by court-martial in 2013 of espionage and other crimes for providing more than 700,000 documents, videos, diplomatic cables and battlefield accounts to Wikileaks, though the final 28 years of her sentence were later commuted by President Barack Obama.
White House press secretary Sarah Huckabee Sanders said Sunday that President Donald Trump was just joking in 2016 when he said he loved WikiLeaks. Trump had heaped praise on the anti-secrecy..
U.S. President Donald Trump told reporters on Thursday, "I know nothing about WikiLeaks. It's not my thing," despite a recorded history of referencing the group frequently throughout his campaign..
Assange arrested: Trump says "Wikileaks isn't his thing"
U.S. President Donald Trump told reporters on Thursday, "I know nothing about WikiLeaks. It's not my thing," despite a recorded history of referencing the group frequently..
Fox News host Sean Hannity is coming to the defense of Wikileaks and its recently arrested founder Julian Assange. Veuer's Nick Cardona has that story.
U.S. President Donald Trump said on Thursday he did not have an opinion about the arrest of Wikileaks founder Julian Assange, who faces the prospect of extradition to the United States over the..
| 0.113176 | 1.583296 | -8.621131 | 1.601156 | 0.962629 | -7.466591 | -4.786896 | -0.240145 |
80,495 |
Why you should join the CCAA!
When you join the Canadian Contemporary Acupunture Association not only do you benefit from everything listed below, you also are in contact with colleagues in your profession. Share ideas, techniques, new innovations and procedures on our blog, on facebook and on our wbsite!
The annual CCAA membership fee is $125 + 16.25 (HST) = 141.25. Membership is set for a duration of one year from date of joining. Individuals can join online, quickly and securely by credit card through Paypal.
| 4.749369 | 0.386851 | -8.997114 | 0.685553 | 4.792339 | -4.753417 | -3.038341 | -0.414018 |
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Jessica is an elegant silk shantung mermaid style with a deep sweetheart neckline and sweep train that bustles up.
There are buttons down the back zipper that stop at the waist so the dress can be worn with a sash. The hem detail is a hand pleated silk organza. Abigail topper and Abbey Sash sold separately.
| 4.769022 | -0.084599 | -9.729103 | 0.326867 | 1.118833 | -4.868313 | -4.769548 | -0.912967 |
75,003 |
Nathan Smith’s second half header separated the two sides at Vale Park.
“It was a scrappy goal to concede,” Beech told Dale PlayerHD.
“Smith, who played very well today, got the contact and that slight deflection saw it loop into the far corner.
“It was a wide free-kick again. We didn’t defend it on Saturday and we didn’t defend it again tonight. It cost us winning the game on Saturday and it cost us an opportunity to win the game tonight.
“There wasn’t too much in the game. If you look at the first half in terms of goal contact, shots at goal etc, then Rochdale were in the ascendancy. Port Vale had that one chance when Anton Forrester had a chance with his header.
“We spoke to the players at half-time about how we wanted to shorten up the game and the passing – pass and penetrate, which is what we’re good at, and if anything, we went a little bit too long in the second half.
Beech confirmed that Joe Rafferty missed the game due to a groin problem, while Manager Keith Hill was out of action due to a medical problem.
The full interview Dale PlayerHD.
| 4.76612 | 0.766147 | -10.676736 | 0.077884 | 3.568514 | -6.554829 | -4.782555 | -0.819464 |
96,643 |
Our client is one of the famous company in the construction industry providing outstanding service. They delivered several mega and highly successful projects.
You will be reporting to the project manager of the company. The manager is a very hands on person and experienced in the construction industry. He will be your mentor and guide you through your project.
| 4.76632 | 0.234234 | -7.933794 | 0.474319 | 2.527149 | -11.451013 | -4.774801 | -1.022246 |
28,896 |
Did you know there are plants you can grow in your own back yard that can actually benefit your hair? In honor of National Garden Month, we are growing more than just hair here at HairMax! What better way to officially kick off spring than a little DIY gardening that won’t just make your yard come to life, but also help your hair com back to life. From superfoods to herb and vegetables, here are 7 of the best foods to grow at home for better potential hair health.
Who knew that some of the best and healthy solutions for hair loss may be found in your backyard! Herbs and plants have been used to help promote hair growth for years, because they are said to help your scalp in so many different ways. Some say you can use them topically and others can be eaten or made into tea, for example, here are some recent posts about the benefits of 5 Essential Oils That Promote Hair Growth and the 5 Foods to Boost Hair Growth.
Let’s take a look at some of the best plants and herbs you can easily, and inexpensively, grow yourself!
In last week’s post about using rosemary essential oil, we learned that there’s increasing scientific evidence that rosemary oil can help boost hair growth. Along with being a powerful stimulant to increase blood circulation to the hair follicles, this oil can help fight your dry and flaky scalp due to the antibacterial and antifungal properties.
Hair health aside, many people use rosemary as a natural remedy for relieving pain or skin irritation and soothing indigestion. The soothing aroma of rosemary is frequently used to help relieve everyday stress, which is also a common cause of hair fall, especially in women. It is also said that the aroma of this herb is a natural deterrent for garden pests, like mosquitoes!
While you can grow your own rosemary from a seed indoors and transferring it outside in the spring, it is much easier to grow it from clippings.
Keep soil uniformly moist, allowing it to dry out between watering and be sure to have good drainage to prevent mildew/root rot.
Cut stems for fresh rosemary, or use a rack/hang upside down in bunches to dry. Once dry, strip leaves from the stems.
Chia seeds have been popping up everywhere lately, from beauty products to restaurant menus, and for good reason. They are perfect to sprinkle on top of salads, add to smoothies or water, but if you’ve bought them before, you’ll understand why growing it yourself makes total sense as a small bag can cost you up to $10!
In a recent post about this powerful little seed we discussed the many benefits of chia seeds, like how they have 10 grams of fiber in a 2 tablespoon serving, they are jam packed with antioxidants that help protect the body from free radicals, aging and cancer. 60% of chia seeds are composed of omega-3s that can help improve the integrity of keratin and elastin in your body so your hair is able to be thicker and more voluminous.
Considering the size of a mature chia plant takes up a good amount of space and grows taller than most herbs, having a backyard is suggested. So, if you are planning on growing chia in a pot, you will need one on the larger side and any specialist at your home improvement store can help advise you on what supplies you’ll need.
Sprinkle a few seeds over the soil and rub gently to cover them.
Harvest as soon as most of the petals have fallen off the flower.
The fastest and easiest way to extract the seeds is to rub dried flower heads with a flat hand and then isolate seeds using a strainer.
Green tea (Camellia Sinensis) is one of the most common Chinese herbal remedies for everything from weight loss to hair loss! How can it help your hair? Well, green tea can improve blood circulation to your scalp giving hair follicles more nutrients and is also a DHT blocker, the compound that causes hair loss.
You can grow from seed or clippings, or you can buy a plant from a nursery.
When starting from seeds, it can take years to make into tea, as it takes at least 3 years to grow a plant with enough leaves for a harvest. Take care of it and you’ll have tea for the next 50 years!
Cover the seeds lightly with soil and keep the soil damp and warm.
When new shoots appear in spring, it’s called a flush.
Steam them on stove top for a minute or two or roast in skillet.
Along with chia seeds, Kale has become one of the more popular greens, popping up on menus, beauty products, and even pet foods! It should be no surprise when you look at why kale is such a powerhouse plant. Having only 33 calories and around 3g of protein per raw cup, kale is also rated as one of the best veggies for absorbing free radicals in the body.
It is also packed with vitamins A, C, K, B and omega-3 fatty acids, which are important for hair health and growth. While kale can have a bitter, ridged, rough texture, if a younger plant is harvested, commonly known as baby kale, the leaf will be closer to spinach and a little sweeter. You can also marinate it in some lemon juice and dash of olive oil to break the leaves down for salads or raw consumption.
Early spring to early summer for best plant time.
Plant seeds ¼ to ½ inch deep into light soil that is well-drained.
After about 14 days, move seedlings to 8 – 12 inches apart.
Water regularly, but careful not to overwater.
When leaves are the size of your hand, pick a fist full, but not the bud (in the top center of the plant) to keep producing.
When I think of basil, I think of caprese salads, margharita pizzas, and pesto sauce! However, basil leaves have been historically used in medicine, as well as diet, in many cultures. The plant has antioxidant, anti-inflammatory, antibacterial and anti-fungal properties. When broken down into an essential oil, it is said to potentially have stimulant properties that, when applied topically, can increase blood flow to the scalp in turn should help hair growth.
Basil grows easily from clippings, but can be grown by seeds indoors as well.
Keep soil moist. In hotter weather water freely.
FIY basil blossoms, if left on, have a great smell and said to attract pollinators to your garden!
Beets have been a popular salad topping or side dish for many years, and for good reason! Commonly known as “nature’s multivitamin”, beets can help your body fight off the common cold or some even say help against cancer!
Not only are the roots beneficial, but the leaves are just as edible and healthy. It has been said that beetroot can help complete your nutritional deficiency, help prevent scalp inflammation and might even help reduce you stress level.
Plant beet seeds ½ to 1 inch deep.
Keep soil moist until sprouts emerge.
Gently space seedlings 3 – 4 inches and water well.
Also known as “vegetable confetti”, they are one of the easiest greens to grow, especially for kitchen herb gardens or window boxes. Scientists say they have a greater concentration of vitamins and minerals versus fully grown greens.
If you look for them at the store, you will see how cost-efficient it is to grow yourself. There are over 40 different types of microgreens you can plant, like arugula, chard, sorrel, and Russian kale.
In one study, the younger greens had four to six times more beneficial nutrients. There are several different microgreens to choose from, including Microgreens Milk Mix seeds, which are ready to harvest within five to ten days.
Read seed packet for special requirements.
Sprinkle seeds over soil and cover with a very thin layer of soil.
Dampen surface with water spray bottle, or cover container with lid/clear plastic wrap until seeds sprout.
Mist with water once or twice a day to keep soil moist not wet.
Discard covering once sprouted and continue to mist daily.
When leaves arrive, snip above soil line and store in refrigerator.
Results differ for everyone so it’s important to try different approaches… even if these foods don’t really effect your hair health, your body will definitely thank you for all of the healthy nutrients and vitamins! Comment on which ones you try and if you see any difference!
Using products with essential oils, such as the HairMax for density products, will help fortify and revitalize hair. Infused with a synergistic blend of DHT blockers, anti-oxidants and therapeutic botanicals to restore balance, optimize scalp health and enhance the vitality, thickness and volume of your hair. These gentle products cleanses your hair without the harsh effects of sulfates that strip essential oils from your hair.
| 2.587576 | 2.077268 | 0.483197 | 2.471035 | 6.443686 | -0.422412 | 3.185035 | 1.830789 |
19,659 |
With it being Labor Day weekend here in the States, lots of people are on vacation, and vacation means road trips!! A familiar sight to most travelers this weekend will be those ubiquitous orange signs. 'Left Lane Closed Ahead', 'Workers Present', 'Prepare to Stop', 'Detour'. These signs mean waiting is ahead! :-D In Michigan, the old joke was that the orange traffic cones were the state tree. :-P As an homage to all the travelers out there this weekend, I decided to do a construction sign manicure!
I used OPI Alpine Snow Matte as a base with Color Club Wham! Pow! over it for all nails but the ring finger, where I used OPI Ginger Bells as a base, with CND Electric Orange over it. For the black, I used American Apparel Hassid, and for the stripes on the traffic barrel, I used OPI Alpine Snow Matte with Sinful Colors Smokin' Hot over the white stripes to give them the 'reflective' shimmer, and Color Club Wham! Pow! for the orange stripes, with Sinful Colors Smokin' Hot over it for the reflective shimmer. Topped everything off with 2 coats of Seche Vite top coat.
Gotta love construction, and it's seemingly EVERYWHERE in Vegas.
Such a fun mani! I onced dressed up for Halloween as The Pretenders song "Middle of the Road"... all black with road signs here and there. The one on my hip said 'Danger Curves Ahead' and yellow stripes down my body. Orange cone hat, pretty funny.
This is so adorable. The thumb and middle are my favorite.
Love this construction is a Pita but this made me smile!
Wow!! This is such a cute mani!
I live in Vegas, too, and you're not kidding about the construction!
OMG this is one of my favorites so far. Very original and accurate lol. Awesome!
oh my lord, I work for the highway department, and I would LOVE to have these nails!
I love the theme of your nails this week, how creative sweetheart.
| 4.745705 | 0.831262 | -6.420082 | 0.774365 | 1.092849 | -5.084594 | -4.73827 | -0.309975 |
52,071 |
AEG Facilities, the venue management subsidiary of AEG, and SMG, an Onex portfolio company and venue management company, have signed a definitive agreement to merge.
This combination will create a new, standalone global facility management and venue services company that will operate as ASM Global (“ASM”).
Onex and AEG’s subsidiary will each own 50 percent of the company following the completion of the transaction.
The biannual MAGIC fashion trade show is reinventing itself by offering a new one-stop shopping experience at a single venue, following feedback from MAGIC buyers.
Diversified Communications’ President and CEO Theodore Wirth promoted Mary Larkin to President of Diversified Communications’ U.S. operating division.
“In 2014, we took the unusual step and established a three-person EVP team. Bill Springer, Mike Lodato and Mary Larkin were able to grow the business, but three-person leadership teams are challenging at best and we felt it was the right time to appoint one leader,” Wirth said.
Is the next recession coming? Joe Popolo, CEO of Freeman, doesn’t seem to think so. In the past twelve months, the Dallas-based company completed several acquisitions and sales to stay nimble in the changing marketplace and is gaining ground around the world.
TSNN sat down with Popolo at EFI Connect, a conference for digital imaging and printing that took place last month in Las Vegas, where he shared his thoughts on growing a family company to a $3 billion business, the role of new technologies and overall market trends.
Full-service sourcing, housing and event management company Connections Housing has acquired Par Avion, a full-service convention housing and travel company based in Lawndale, Calif.
Both Connections Housing and Par Avion are women-owned business and are respected leaders in housing and travel services with mutual emphasis on executing superior and seamless events.
In an effort to shed a light on “conscious fashion,” WWDMAGIC will partner with animal rights organization PeTA and animal-friendly outerwear brand Coalition LA at the fashion trade show’s upcoming winter marketplace, set for Feb. 5-7 at Las Vegas Convention Center.
To say that last year was a monumental one for Informa Exhibitions, which is led by CEO Charlie McCurdy, would be quite an understatement.
2018 marked the largest mergers and acquisitions deal in history, with Informa buying fellow U.K.-based exhibition company, UBM, for a whopping $5.2 billion.
Now that the deal has been closed for several months, TSNN sat down with McCurdy to talk through what’s next and some overall exhibition market trends.
With the U.S. government shutdown still in effect — and stretched longer than any other in history — many association meeting planners and trade show organizers are concerned about how this might impact their events.
Destination DC has been actively campaigning to let the world know that the city is open for business and ready to welcome both events and leisure travelers.
Event planners looking for a Pacific Northwest hotel able to accommodate all their meeting guests might want to take a look at the Hyatt Regency Seattle. The new 45-story downtown property, which is now the largest hotel in the region, opened its doors late last year, on Dec. 10.
| 3.124958 | 0.893051 | -6.927096 | 0.077349 | 4.637119 | -6.822337 | -4.774713 | -0.578961 |
80,593 |
Are you considering a placement at Woodville House ?.
Reduce your stress level - Aged Care Connect have been placing residents into residential care since 2002, and have inside knowledge and experience to help you with your important decisions about Woodville House or other aged care homes in the Helena Valley area.
We can provide you with independent and unbiased advice about the financials at Woodville House and other comparison aged care homes in Helena Valley.
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| 4.636803 | 0.65285 | -5.14069 | 0.993639 | -0.515604 | -5.301668 | -4.710452 | -0.27864 |
39,721 |
Get ready for the most sensible Saints Row 4 news piece you will ever read. There will be no dubstep gun, no super-powers, no Presidential swagger. Instead, it's cold, hard statistics, as we take a look at the recently announced system specs for the increasingly ridiculous open world sequel. Who needs a multi-foot rubber phallus when you've got adequate amounts of RAM?
Oh go on then, here's a stupid video of silly things happening.
| 4.767597 | 0.116734 | -7.522739 | -0.146265 | 1.072768 | -7.859436 | -4.454573 | -1.013119 |
60,447 |
Tell the Tea Party to Take a Seat! | Russell Simmons – Mr. President, we got your back!
For the first time in seventeen years, the United States government has shut down. Hundreds of thousands of families across this nation will be hurt by the inaction of a few politicians who have successfully hijacked their own party. The Tea Party Republicans, led by Senator Ted Cruz, were able to close the doors of Congress, over their disagreement with the Affordable Care Act; a law that will provide health care for millions of Americans who have been living their lives in fear of getting sick. When the history books are written, this law will prove to be a turning point that pointed our nation towards a more compassionate America, a country that no longer only took care of the privileged, but rather took care of all of its people. Republican or Democrat, if you’re American, you should want to take care of your brother and your sister.
It has been painstakingly obvious that there are some members of Congress that are severely threatened by President Obama’s success. No matter what he does, they don’t like it. They are not working for the betterment of the people, they are working for the betterment of themselves, and often times, the betterment of their puppet master’s wallet.
Barack Obama has shown time and time again that he will stand up for the American people. He has shown that he will risk his own political career, like speaking directly with the Iranian President, because he knows it’s the right thing to do. He will call on a distant friend in Russia and ask them to help resolve a conflict with one of their close friends, Syria, so our nation can avoid war at all costs. He will challenge the mighty powerful gun lobby because he can no longer bare the pain on the faces of mothers and fathers who have buried their children before they could say goodbye. He is a man of dialogue. He is a man who believes in exhausting all of his resources before making a decision. He is a man who will constantly take the higher moral ground. To not work with him is a mistake that could and should cost the Republican Party the majority in the House when the mid-term election occurs next year. If they shut down the government, we will open the ballot box.
While many members of the other side would rather close down the government and hurt the American people, Barack Obama is willing to do the work that will continue to grow our economy, create more jobs, engage in international peace talks and tackle tough issues like health care, immigration and the environment. He is a negotiator, someone who is willing to work through the tough problems our nation faces. It was inspiring to seem him begin direct negotiations with the new Iranian president and work with Vladimir Putin to solve the Syrian problem. But I am proud that he will not negotiate with the minority party in this country with a gun to his head. If the Republicans, specifically the members of the Tea Party, want to play games with our economy, he shouldn’t give them an inch. Tell the Tea Party that they can’t hijack our government and to take a seat. Stand strong, Mr. President, we got your back.
| -3.372506 | 1.23092 | -3.531596 | 0.931207 | 6.27605 | -4.503866 | -2.777578 | 0.120295 |
44,488 |
α-Mangostin (αMG), a xanthone that is contained in large amount in Garcinia mangostana Linn, has been demonstrated to possess several antitumor properties under in vitro and in vivo conditions . The wide range of pharmacological activities of αMG and the low frequency of its adverse effects have contributed to propose this natural substance as an adjuvant in cancer therapy . Recently, we described novel harmful effects of αMG against three-dimensional (3D) multicellular tumour spheroids (MCTSs) generated by MDA-MB-231 human breast cancer cells, such as disaggregation and size reduction of the tumour bulk that were paralleled by a decrease in cell viability and motility . Instead of cell monolayers, MCTSs are usually preferred as a laboratory model for pharmacological investigations because better simulate the 3D architecture of solid tumours, especially those regions that are not well perfused due to an inefficient vascularization . The thickness of MCTSs generates a gradient of nutrients, oxygen and waste compounds from the surface to the core that affects not only biological functions but also cell response to drugs . In particular, the inner layers of MCTSs become hypoxic when the radius exceeds 120 μm . Moreover, under hypoxic conditions tumour cells can undergo a selection that makes them more resistant to various stresses and that generates cancer stem cells (CSCs) [7, 8]. MCTSs can be also useful to study drug diffusion since it depends on the thickness of the tumour and the features of cell-to-cell and cell-to-matrix contacts .
Bioavailability, pharmacokinetics and pharmacodynamics of antitumor drugs are fields on continuous improvement. One of the most appealing strategies that have been investigating is the use of nanoparticles (NPs) as a vehicle for intravenous infusion . NPs in the range of 100 nm diameter and covered by lipophilic/polyethylene glycol layers are not recognized by the reticular endothelial system and hence the lifespan of the transported drug in the body is increased . In addition, according to the “enhanced permeability and retention” (EPR) effect, small NPs preferentially concentrate into the tumour mass rather than in normal tissues . This condition seems to occur thanks to the synergistic process of NP leakage from large capillary gaps and the subsequent tissue entrapment of NPs due to a poor lymphatic drainage. Tumour cell selectivity can be further improved by conjugating NPs to ligands that target exclusive, or more largely expressed, superficial molecules [13, 14]. In particular, aptamers are usually considered as superior ligands in respect to antibodies because they are not degraded by proteases and can become more resistant to the nuclease attack through simple modifications in their phosphate backbone . Moreover, a receptor-mediated process accelerates the entry of drugs into the cell when they are carried by ligand-conjugated NPs . Therefore, NPs targeting specific tumour cells can be considered as a suitable tool to reduce the dosage of the drug cargo and, therefore, the occurrence of adverse effects of chemotherapy.
According to these concepts, we generated MCTSs by a MCF-7 breast carcinoma cell line and the antitumor effects of αMG, as a free compound or encapsulated in lipidic NPs, were evaluated. We found that very low concentrations of αMG delivered by NPs caused a significant reduction in spheroid compactness, without increasing cell invasiveness. Since MCF-7 cells largely express CD44, the antitumor activity of αMG-loaded NPs conjugated to a CD44 thioaptamer was also investigated.
Reagents were purchased from Sigma-Aldrich (St. Louis, MO, USA), unless otherwise stated.
MCF-7 human breast carcinoma cell line (the European Collection of Authenticated Cell Cultures, ECAAC) were expanded in culture flasks under standard conditions (37 °C, 5% CO2, 95% humidity) or subjected to a low oxygen tension (1% O2, 94% N2, 5% CO2). Cells were cultured in complete Dulbecco's modified Eagle medium (DMEM), containing 2% fetal calf serum (v/v), 100 U/ml penicillin and 100 μg/ml streptomycin. The culture medium was routinely replaced twice a week. For cell expansion, subconfluent cells were detached using a solution of 0.05% trypsin in 0.53 mM EDTA. MCF-7 cells were cultured also as monolayers on 96-well flat-bottomed plates at the density of 1x104 cells/well.
For the initial characterization of the spheroids, MCF-7 cells were seeded in ultra-low attachment (ULA) 6-well flat-bottomed plates (Corning; Sigma-Aldrich) at densities ranging from 1x103 to 2x104 cells/ml. The culture medium was serum-free DMEM/F12 (1:1 v/v) containing 2% B27 (ThermoFisher Scientific, Waltham, MA, USA), 20 ng/ml epidermal growth factor (EGF, Peprotech, Rocky Hill, NJ, USA), 20 ng/ml basic fibroblast growth factor (bFGF, Peprotech), 100 U/ml penicillin, and 100 μg/ml streptomycin (MCTS medium). To perform a high throughput screening, 200 μl of cell suspension in MCTS medium was seeded on each well of ULA 96-well round-bottomed plates (Corning) and to encourage cell aggregation, the plates were centrifuged at 100 g for 3 min. Under this condition, spheroids of diameter ranging between 250 and 300 μm were generated after three days. Then, some MCTSs were treated with different concentrations of αMG dissolved in 0.1% (v/v) dimethylsulfoxide (DMSO), while control MCTSs were exposed only to the vehicle.
Images were captured using an inverted microscope (IX50, Olympus Italia, Segrate, Italy), equipped with an Olympus camera, and imported into Image-J software (Fiji, http://imagej.nih.gov). Using the graphic utilities of Image-J, the largest (equatorial) border of each spheroid was manually drawn and the pseudo-circular area of its phase-contrast image was calculated. After background subtraction, the MCTS density was measured using the “mean grey” command of the software applied to the 8-bit inverted images of each spheroid. This parameter provided the grey half-tone intensity-to-area ratio of the pseudo-circular images of MCTSs. Morphological measurements were performed each day of treatment and expressed as percentage of those obtained at day 3 after cell seeding (100%). Some spheroids grew for three days on ULA plates and then were transferred to adherent 96-well flat-bottomed plates (Corning) that were coated with 100 μl of 0.1% (w/v) gelatine or Matrigel (Corning) for better simulating the extracellular matrix (ECM) environment of solid tumours .
MCF-7 cells at the density of 1x104 cells/well were seeded on adherent 96-well flat-bottomed plates and cultured as monolayers in complete medium for 48 h . Then, PrestoBlue Cell Viability Reagent 10X solution (ThermoFisher Scientific) was added in each well at a 10% final concentration. Fluorescence was measured at 530 nm excitation and 590 nm emission on a Wallac VICTOR2 multiwell plate reader (Perkin Elmer, Milan, Italy) 4 h after dye addition.
Lipid-polymer combinational nanoparticles were synthesized from polylactic-co-glycolic acid (PLGA), soybean lecithin and 1,2-diasteroyl-glycero-3-phosphoethanolamine-N-carboxy(polyethylene-glycol)2000 (DSPE-PEG2000-COOH) using a nanoprecipitation technique combined with self-assembly . PLGA (50:50, M.W. 30-70 kDa) was first dissolved in acetonitrile at a concentration of 1 mg/ml. Lecithin and DSPE-PEG2000-COOH were dissolved with a 7:3 molar ratio in 4% ethanol aqueous solution at 15% of the PLGA polymer weight and heated to 65 °C. Then, the PLGA/acetonitrile solution was added to the lipid/aqueous solution in drop-wise manner, followed by vortexing for 3 min. αMG was added to the PLGA solution in the ratio 1:10 (w/w) relative to the polymer. The solution was then subjected to indirect sonication for 5 min in ice-cold water. The NPs were allowed to self-assemble and the organic solvent to evaporate with continuous stirring for 3.5 h. The remaining organic solvent and the free molecules were removed by washing the NP solution two times in ethanol/water and the third time in distilled water using an Amicon Ultra-4 centrifugal filter with a molecular weight cut-off of 10 kDa (Millipore; Sigma-Aldrich). The NPs were sonicated again, filtered by 200 nm cut-off (Corning), and divided in two aliquots of 1 ml each. An aliquot was air dried for about 1 h, weighed, and dissolved in acetonitrile plus 30% phosphate buffer saline (PBS), pH 7.2, for the spectrophotometric measurement of drug encapsulation (peak of absorbance of αMG at 320 nm). The second aliquot of 1 ml was immediately used to perform the conjugation with the aptamer. The remained suspension of NPs was stored at -20 °C. Fluorescent nanoparticles were also prepared by adding 10 μl of the fluorochrome Nile Red at the concentration of 1 mg/ml.
A DNA thioaptamer that specifically binds to CD44 according to the formulation TA6 described by Somasunderam et al. was synthesized by Trilink Biotechnologies (San Diego, CA, USA). The 73-mer oligonucleotide is a back bone-modified aptamer in which the non-bridging phosphoryl oxygens are substituted with sulphur. This change of structure renders the aptamer more resistant to the cellular degradation exerted by nucleases. The thioaptamer (M.W. 24,229.0) was linked to an amino group at the 5' end to allow the carboxyl group of DSPE-PEG2000-COOH to form a carbamide covalent bond. For this purpose, we used the two catalysts 1-ethyl-3- (3-dimethylaminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS) according to the manufacturer's instructions (ThermoFisher Scientific). Briefly, NPs (10 mg) were dissolved in 1 ml of distilled water, filtered with an Amicon Ultra-4 10 kDa (Millipore) and resuspended in 1 ml of buffered 0.1 M 2-(N-morpholino)ethanesulfonic acid, 0.5 M NaCl, pH 6.0, containing a molar concentration of EDC and NHS 10-fold and 25-fold higher than DSPE-PEG2000-COOH, respectively. NP suspension was shacked gently at room temperature for 15 min. The resulting NHS-activated NPs were washed twice in distilled water with Amicon Ultra-4 10 kDa filters, resuspended in 1 ml PBS and conjugated to 3 nmoles of thioaptamer corresponding to a 1:100 ratio with respect to 0.85 mg DSPE-PEG2000-COOH used for the synthesis of 10 mg NPs. To this purpose, 30 μl of 100 μM thioaptamer in PBS was added to 1 ml PBS containing 10 mg NHS-activated NPs and stirred at room temperature for 2 h. To remove the free thioaptamer, the final solution was washed three times in distilled water, using the Amicon Ultra-4 10 kDa filter, and the NPs resuspended in distilled water at the concentration of 10 mg/ml.
NP size was measured by tuneable resistive pulse sensing (TRPS) using the qNano Nanoparticle Analyser V2.0 (iZON Science, Christchurch, New Zealand) equipped with a fluid cell module of 300 nm nanopores (NP300) and operated by the V3.1 Control Suite software.
The ability of NPs, free or conjugated to the thioaptamer, to enter cells was evaluated by phase contrast and fluorescence microscopy (Olympus IX50) using CD44+ human bone marrow mesenchymal stromal cells (BM-MSCs; TebuBio, Magenta, Italy) at the density of 4 x 103/ml. NPs were also observed by scanning electron microscopy (JSM-5200; JEOL, Tokyo, Japan).
MCF-7 cells were homogenized in a glass tissue grinder in 20 mM HEPES, pH 7.5, containing 5 mM dithiothreitol, 2 mM EDTA, 0.1% CHAPS detergent, 0.1% Triton X-100, and protease inhibitors; then, they were centrifuged at 15,000 g for 15 min. The supernatant was diluted in loading buffer (2% SDS, 5% glycerol, 0.002% bromophenol blue, 4% β-mercaptoethanol in 0.25 M Tris-HCl, pH 6.8) and denatured by boiling for 3 min. Aliquots corresponding to 80 μg protein were analysed by SDS-PAGE (7.5% gel). Proteins were transferred onto a nitrocellulose membrane for 1 h. This membrane was then saturated with 5% dry milk for 1 h, washed with Tris-buffered saline, and probed overnight at 4°C with the specific primary antibodies (1:500 mouse monoclonal anti-HIF-1α and 1:1,000 mouse monoclonal anti-β-actin; Santa Cruz Biotechnology, Heidelberg, Germany). The membrane was then incubated for 1 h with the secondary antibody (1:2,500 horseradish peroxidase-conjugated species-specific anti-IgG; Santa Cruz Biotechnology).
Values are expressed as mean ± standard error of the mean (SEM). Linear regression analysis and one-way analysis of variance (ANOVA) followed by Bonferroni multiple-comparison test were performed using GraphPad Prism 4.0 software (San Diego, CA, USA). P < 0.05 was considered statistically significant.
MCF-7 cells at the density of 1x104 cells/well were cultured as monolayers on 96-well flat-bottomed plates under normoxic conditions. The treatment with 0.1-20 μg/ml αMG for 48 h caused a bi-modal and dose-dependent decrease in cell viability. Figure 1 shows that cells were markedly damaged by concentrations of αMG up to 1.0 μg/ml, while higher doses up to 20 μg/ml led to a less accentuated drop in viability.
Effects of free αMG on the MCF-7 cell monolayer. The viability of 1x104 MCF-7 cells was reduced after treatment with free αMG for 48 h in a dose-dependent manner. The cells were greatly affected by 0.1-1 μg/ml αMG that caused a sharp decrease in their viability. A further damage to cells was observed using higher concentrations of αMG, although their responsiveness was reduced. Values were subjected to linear regression analysis and are expressed as mean ± SEM of duplicated experiments.
As preliminary characterizing set of experiments, MCTSs were produced in ULA 6-well plates by seeding 1x, 5x, 10x and 20x103 MCF-7 cells/ml and the increasing size of the spheroids with cell density was verified (Figure 2a). Then, to obtain a high-throughput availability of MCTSs, a single spheroid per well was grown in ULA round-bottomed 96-well plates for 15 days (Figure 2b). The seeding density of 1x104 cells/well was chosen because represented the best condition to obtain spheroids that were not too large for the limited size of the well but enough compact and well-shaped to perform appropriate morphological investigations.
Effects of free αMG on MCTS size and density. (a) MCF-7 cells seeded at 1x, 5x, 10x and 20x103 cells/ml in ULA 6-well flat-bottomed plates generated MCTSs of increasing size after 7 days. The spheroids merged into larger aggregates at the highest cell density (magnification: 50 X). (b) The images show a single MCTS per well that was grown in ULA 96-well round-bottomed plates for 15 days (representative images of triplicate experiments). The optimized seeding density of 1x104 cells/well allowed to obtain 3D bodies with a circular profile and homogeneous cellular distribution (magnification: 50 X). The spheroids treated with free αMG for 24 h (c) and 48 h (d) were negatively affected by doses higher than 0.8-1.0 μg/ml (n = 2). MCTSs generated in the presence of 1.0-20 μg/ml free αMG showed a smaller area and a parallel increase in density with respect the untreated MCTSs. (e) Representative phase-contrast images of the MCTSs treated for 48 h with increasing doses of free αMG (magnification: 50 X). The numerical values correspond to the concentrations of αMG expressed as μg/ml. At the highest dose, a darker region of cellular necrosis is clearly visible.
The treatment with free αMG produced damages to the spheroids that were shown as changes in equatorial area and density (Figure 2c, 2d). The lowest concentrations of αMG that significantly reduced the MCTS area were 3 μg/ml and 1 μg/ml, administered for 24 h (p < 0.05) and 48 h (p < 0.01), respectively. Conversely, the MCTS density underwent a parallel increase that reached statistical significance after treatment with αMG at the concentrations of 10 μg/ml for 24 h (p < 0.05) and 3 μg/ml for 48 h (p < 0.05). The irregular edges of the MCTSs and the homogenous distribution of their density observed at the highest doses (Figure 2e) were considered as further signs of αMG toxicity.
The mean diameter of NPs was 227.0 ± 88 nm and 174.0 ± 29 nm before and after filtration, respectively (Figure 3a, 3b). Both diameter and size distribution of NPs were consistent with the images obtained by SEM (Figure 3c). The fluorescent dye Nile Red was loaded in NPs to trace their uptake inside cells. BM-MSCs were chosen to better perform this test because they are larger than MCF-7 after adhesion on plates of polystyrene. BM-MSCs were incubated with NPs and observed by a combination of phase contrast and fluorescence microscopy. The process of NP incorporation into cells was effective after 24 h (Figure 3d, 3e) and larger aggregates of NPs were generated after 48 h of incubation (Figure 3f).
Characterization and cell uptake of NPs. (a) The size distribution of NPs measured just after their production was 150-380 nm. (b) The range of NP diameter was restricted to 110-260 nm after filtration, with a mean value of 174.0 ± 29 nm. (c) NP size and distribution were consistent with the images obtained by SEM. (d, e) BM-MSCs were incubated with Nile Red-loaded NPs and contemporary observed by phase contrast and fluorescence microscopy after 24 h. (f) Most NPs fused into larger aggregates after 48 h. Images are representative of duplicate experiments.
Morphological changes of MCTSs grown in Matrigel and treated with NPs. NPs loaded with αMG were able to dissociate the spheroids. MCTS treatment for 48-72 h with NPs that were not conjugated to the thioaptamer (NP[-]) and carrying 0.1 or 0.5 μg/ml αMG led to cell detachment after 48-72 h. NPs conjugated to the thioaptamer (NP[+]) and carrying 0.1 μg/ml αMG reduced the size of the spheroids, while NPs loaded with 0.5 μg/ml αMG provoked MCTS disaggregation. The images are representative of two separate experiments (magnification: 50X).
The amount of αMG loaded in NPs was 1.4 μg/mg. A suspension up to 1 mg/ml of NPs without αMG in complete medium did not affect growth and viability of cells, irrespective of the presence or absence of the thioaptamer (data not shown).
MCTSs were grown in Matrigel and their morphology was observed after 24, 48 and 72 h of treatment with NPs (Figure 4). The concentration of 0.1 μg/ml αMG carried by NPs without thioaptamer (NP[-]) was sufficient to loosen MCTS cells in a time-dependent manner. The dose of 0.5 μg/ml αMG also provoked a robust dissociation of MCTSs, independently of the absence or presence of the thioaptamer. The administration of NPs conjugated to the thioaptamer (NP[+]) at 0.1 μg/ml αMG reduced the size of MCTSs and produced a lower effect on cell aggregation.
αMG conveyed by NPs caused the disaggregation of MCTSs also when they were grown in gelatine (Figure 5). An initial drop in spheroid density was observed just after 24 h of treatment with 0.1 μg/ml αMG. Maximal spheroid dissociation was obtained using NPs with 0.5 μg/ml αMG for 72 h, as it was shown by the lowest density and the highest area of the MCTSs. The presence of the thioaptamer linked to NPs (NP[+]) attenuated the MCTS expansion after treatment with 1.0 μg/ml αMG for 48 h (p<0.01) and 72 h (p<0.05), as it was shown by the lower values of the area relative to NP[-]. However, the reduction in density produced by NP[+] was of the same magnitude of that obtained with NP[-] at the corresponding αMG concentrations.
Morphological changes of MCTSs grown in gelatine and treated with NPs. The treatment with αMG-loaded NPs increased the area of MCTSs (upper slopes) and caused a parallel drop in their density (lower slopes). The lowest dose of αMG that provoked a decrease in MCTS density was 0.1 μg/ml just after 24 h of treatment. The expansion of the area was less pronounced using NPs conjugated to the thioaptamer (NP[+]) than that caused by NPs without thioaptamer (NP[-]). *p < 0.05 and **p < 0.01, comparing the same concentrations of αMG carried by NP[+] vs NP[-]. #p < 0.05 and ##p < 0.01, comparing NP[-] vs the corresponding untreated MCTSs. §p < 0.05 and §§p < 0.01, comparing NP[+] vs the corresponding untreated MCTSs. Micrographs show the dramatic changes of MCTS morphology after treatment with NPs at concentrations of αMG up to 1.0 μg/ml delivered for 72 h (magnification: 50X). The numerical values under the images are concentrations of αMG expressed as μg/ml.
Effects of NPs on HIF-1α cellular levels. MCF-7 cells were exposed to 1% O2 and the presence of HIF-1α was evaluated after treatment with αMG-loaded NPs. The administration of 0.1 μg/ml αMG for 48 h was not sufficient to reduce the amount of HIF-1α, while 0.5-1.0 μg/ml provoked a decrease of its levels. The figure shows representative lanes with corresponding densitometric measurements of duplicated experiments.
MCF-7 cell monolayers were exposed to 1% O2 tension for 48 h and the ability of αMG to affect the intracellular levels of hypoxia-induced factor-1α (HIF-1α) was investigated. Under these conditions, it was possible to detect HIF-1α by western blot and to assess that 0.5 µg/ml and 1.0 µg/ml αMG encapsulated into NPs reduced its cellular concentrations in a dose-dependent manner (Figure 6), irrespective of the absence or presence of the thioaptamer. Similar effects were also obtained using free αMG at the concentrations of 0.5 µg/ml and 1.0 µg/ml (data not shown).
In the present study, we evaluated the ability of NPs containing αMG to cause damage to MCF-7 cells grown in 3D as MCTSs. A robust derangement of spheroids was evidenced by the irregular shape of their edge accompanied by a parallel dissociation and decrease in density of the tumour bulk. The augmented distance between cells that was observed after treatment with αMG-loaded NPs did not occur only at the periphery of the MCTSs but also in the innermost layers, indicating that this effect of αMG was extended to the overall volume of the spheroid. The antitumor activity of αMG delivered by NPs was investigated using MCTSs growing in Matrigel or gelatine. Both gels are usually employed to simulate the ECM of MCTSs but with different analytical end-points for tumour aggressiveness investigations. Specifically, Matrigel provides a suitable support for tumour invasion assays, while gelatine is a better substrate to evaluate cell migration resembling cell dissemination from a solid microtumour or micrometastases .
In our recent study , we underlined that αMG was able to dissociate MCSTs generated by MDA-MB-231 breast cancer cells without increasing their tendency to migrate in a gelatine environment. The cells of these spheroids even reduced their motility when exposed to αMG, an antitumor effect that was also demonstrated in carcinomas deriving from other tissues [22, 23]. We also reported that MCF-7 cells of MCTSs could not migrate in gelatine-coated plates because of the low aggressiveness of this breast cancer cell line. In the present study, the spheroids cultured on Matrigel- or gelatine-coated plates significantly reduced their compactness after treatment with αMG-loaded NPs but did not show any sign of invasiveness. The lack of invadopodia conferring a characteristic “starburst” pattern to MCTSs was a further confirmation that the looser aggregation of cells was not paralleled by an increase in malignancy. Therefore, the detachment of cells from MCTSs caused the by αMG-loaded NPs can be really considered a significant anticancer effect that is not accompanied by the risk of increased invasiveness or metastatic spreading.
The lowest concentration of αMG as a cargo of NPs that provoked a substantial reduction in spheroid density in the presence of gelatine was 0.1 μg/ml and the greatest disaggregation was obtained with 0.5 μg/ml αMG. It is worth noting that these doses of αMG delivered by NPs are about tenfold inferior to those provoking damages to MCF-7 MCTSs with free αMG. Moreover, αMG delivered by NPs dissociated MCTSs that were cultured in Matrigel or gelatine. Thus, these results suggest that: (i) NPs are suitable vehicles allowing αMG to damage tumours at very low concentrations; (ii) the αMG-dependent loss of contacts shown by MCF-7 MCTS cells involves the presence of a gel containing collagen fibres. The finding that αMG can inhibit the adhesion of MCF-7 cells to type I collagen supports the hypothesis that some components of the ECM are involved in the dissociation of MCTSs induced by the xanthone. It has been also reported that an inadequate contact of collagen to integrins β represented an early step blunting the FAK/Akt/ERK cascade that, in turn, provoked the downregulation of the NF-kB-driven expression of MPP2 and MPP9 metalloproteinases . This last effect is considered one important mechanism responsible for the reduced invasiveness of tumour cells that follows a treatment with αMG . Moreover, Kopp et al. demonstrated that the capability of MCF-7 cells to form MCTSs was related to the activity of NF-kB . Thus, we supposed that the anti-adhesive property shown by αMG-loaded NPs towards breast cancer MCTSs was the result of the weaker bond that MCF-7 cells established with collagen fibres inside the spheroid and the consequent lack of NF-kB activation. Similarly, Ivascu at al. showed that an anti-integrin β1 antibody was able to dissociate MDA-MB-231 spheroids exclusively when they were grown in the presence of 2.5% Matrigel . It is presumably that also under our conditions both Matrigel and gelatine fibres contributed to the supporting network of the growing MCTSs and that αMG counteracted some cellular activity related to the presence of collagen. Moreover, Ivascu et al. demonstrated that the dissociation of MCTSs did not imply the loss of viability of tumour cells . Therefore, the use of low doses of αMG-loaded NPs could be investigated as a non-toxic adjuvant drug for tumour chemotherapy. Indeed, the αMG-driven cell dissociation might facilitate both penetration and diffusion of conventional drugs into the tumour bulk.
When αMG was delivered by the NPs conjugated to the CD44 thioaptamer, a loss in cell contact of tumour spheroids did also occur, but MCTSs underwent a lower size in respect to those obtained with NPs not linked to the thioaptamer. This suggests that a number of cells died or slowed down their process of duplication. To explain this effect, it is important to underline that at least 60% of MCF-7 cells express CD44 and that these cells, by sequestering via a very efficient receptor-mediated process the αMG-loaded NPs conjugated to the thioaptamer, should be subjected to a more severe antitumor activity.
Several molecular mechanisms underlying the αMG action have been described, including the inhibition of HIF-1α in pancreatic stellate cells . In the present study, we also observed that αMG was able to downregulate the protein expression of HIF-1α in MCF-7 cell monolayers after hypoxia activation. Thus, as previously suggested , it is conceivable that αMG can reduce the number of cancer cells that have been adapted to hypoxia by blunting the expression of HIF-1α. It is interesting to note that breast epithelial CSCs, which are protected from drug toxicity in their hypoxic “niches”, largely express CD44 together with the epithelial-specific antigen (ESA), whilst they stain CD24-/low . Consequently, NPs bearing αMG and targeting CD44+ cells could represent a drug able to target both CSCs and cells of the tumour bulk in breast carcinoma. In addition, the clinic-pathological and adverse prognostic implications of the expression of HIF-1α that have been demonstrated in different cancer types [32, 33] reinforce the expectation towards the antitumor efficacy of drugs targeting HIF-1α.
Another advantage of NPs conjugated to a thioaptamer, rather than a normal aptamer, should be their lower clearance due to the elevated resistance that the sulphur-adenine nucleotides offer against the nuclease attack . Moreover, the PLGA core of the NPs used in the present study was covered by phospholipids and PEG that have been demonstrated to increase their in vivo lifespan .
In conclusion, these results underlines how great is the antitumor effect of αMG delivered by lipidic NPs, since very low concentrations of the xanthone as a cargo caused a strong disaggregation of MCF-7 MCTSs. When αMG was loaded in CD44 thioaptamer-tagged NPs, it was still responsible of spheroid dissociation, but the toxic effect was more relevant because accompanied by a reduction in MCTS size. Studies are in progress to ascertain whether the selectivity of αMG-loaded NPs linked to a CD44 thioaptamer may also represent a strategy to destroy CSCs in breast carcinomas.
αMG: α-mangostin; b-FGF: basic fibroblast growth factor; DMEM: Dulbecco's modified Eagle medium; ECACC: The European Collection of Authenticated Cell Culture; EGF: epidermal growth factor; ESA: epithelial-specific antigen; MCTS: multicellular tumour spheroid; ULA: ultra-low attachment.
This study was financially supported by: 1) Fondazione del Monte di Bologna e Ravenna (Italy), project “Selective destruction of hypoxic cancer stem cells by bifunctional nanoparticles” and 2) University of Bologna (Italy), budget from “Ricerca Fondamentale Orientata”.
F. Bonafè, C. Pazzini: concept/design/acquisition of data, data analysis/interpretation.
S. Marchionni: SEM analysis, critical revision of the manuscript.
C. Guarnieri: critical revision of the manuscript.
C. Muscari (principal investigator): concept/design/acquisition of data, data analysis/interpretation, drafting of the manuscript, critical revision of the manuscript.
| 4.39004 | 2.093598 | -2.912446 | 1.631154 | 6.327229 | 1.862023 | 3.381018 | 1.576986 |
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404 E 175th St is a Multi-Family building located in Mount Hope, Bronx constructed in 1931. This 4-story building has 8 units. The building is within Community District 206 and zoned for the following schools - P.S. 058, I.S. 313 School Of Leadership Development, I.S. 339. Nearby transportation include the 2, 4, 5, B, D subway lines.
| 4.768126 | 0.846584 | -4.277703 | 1.488881 | 3.769245 | -4.776681 | -4.633706 | 0.125555 |
34,652 |
Grace, Ambience’s lead stylist and buyer, has always had a love affair with Yigal Azrouel’s designs and fabrics. Yigal has incredible fashion in his DNA and it shows in the versatility, design and fit of his diffusion line Cut25. All the dresses that just arrived will take you to work and with a few accessory changes out to dinner and drinks in the city. Yigal’s Cut25 dress fabrication incorporate two key fabrics this season, scuba and leather, is an urban chic silhouette. Scuba dresses are body conscious in a material that hugs the body in a flattering way as you can see with Cut25 by Yigal Azrouel Scuba Seamed Mini Dress and Cut25 by Yigal Azrouel Scuba Zipper Front Dress. Leather is so important this season and is perfectly placed on the Cut25 by Yigal Azrouel Quilted Leather Shoulder Dress giving a hint of military inspiration by the placement this designer really understands trends and makes them so wearable. Enjoy shopping the line.
| -3.52242 | 0.735329 | -10.027236 | 0.568211 | 3.825773 | -7.300969 | -4.774918 | -0.89238 |
787 |
CEOs and CFOs of private or closely held businesses engage us for audit, tax, employee benefit, and advisory services, to help owners manage their business. We work with companies at all life cycle stages, tailoring our focus and related services to their changing needs – whether their objectives be securing financing, making informed management decisions, responding effectively to competitive challenges, or preparing for the future. We believe that our commitment to the highest standards of quality and the importance of our own reputation ensure that our work product provides immediate credibility to interested parties such as bankers, potential investors and all stakeholders.
U.S. public companies, their executives and advisors operate in a regulated environment in which they face complex and ever changing requirements that call for expert support. EisnerAmper is a PCAOB-registered firm that provides support to our publicly traded companies across a vast array of services including audit, tax advisory, internal audit, SEC accounting and reporting, forensic investigation, 11K pension audits, and litigation support. Clients who engage us for internal audit access our Sarbanes Oxley (section 404) and internal controls expertise. Our external audit clients benefit from working with experienced professionals that understand the importance of anticipating and planning as opposed to simply reacting, thus identifying areas of potential concern as early in the process as possible. For both internal and external audit services, EisnerAmper’s approach is designed to distill insight that will support the oversight responsibilities of managements, board audit committees and individual board directors. We also work with private companies and entities considering IPOs, and are one of the nation’s largest providers of professional accounting and audit services to SEC registrants.
The protection of valuable Intellectual Property assets, including copyrights, trademarks, patents and brands, is a year-round activity with material stakes. Whether discrepancies stem from poor systems, processes and controls, mistakes, personnel turnover, contractual misinterpretations or aggressive deductions, EisnerAmper’s Royalty Audit and Contract Compliance Group can help. Our clients are licensors across a variety of industries around the world, as well as universities and research institutes. We work with entities of all sizes seeking compliance with agreements and fair and accurate dispensation.
EisnerAmper’ s Technical Accounting Advisory Services professionals provide our clients with the technical expertise and insight they require on an as-needed basis, so they can navigate a complex accounting environment without adding additional staff resources. Our transaction support services help guide non-attest clients with complex transactions such as merger and acquisition engagements, divestitures, technical white papers, financial reporting and implementation, restatements, regulatory response, implementation of new standards such as ASC 606, complicated market transactions and IPO readiness assessments/support.
| -4.746513 | 0.89616 | -3.560347 | 0.733473 | 5.867028 | -4.979138 | 2.233786 | 0.188399 |
35,990 |
After suffering with intestional Candida I elected to add Poly MVA to my current list of treatment AS WELL as Transfer Factor Plus. Chronic Fatique is a result of Candida and something I have struggled with all my life. I have seen 15 doctors to no avail. I was always tired before Poly MVA and Transfer Plus. Now I have a steady energy flow for the entire day. I currently take 1/2 tsp. AM, 1/2tsp Noon.
I began with the full complement(8 tsp. per day) of Poly MVA for 10 weeks. Then cut back to 2 tsp. a day with 2 Transfer Plus caps for a couple of weeks.
Considering I have fought this problem all of my life, I would have to say if you keep a strict diet eliminating "Sugars and Wheat" you may do well also. These are REAL KILLERS to any success in overcoming this problem. Poly and Transfer Plus will do you no good if you insist upon eating sugar, wheat and a high carb diet that turns to sugar.
I also, believe in reading Hulda Clark's "A Cure for All Disease". I did her parasite cleanse, liver cleanse and kidney cleanse and I keep up the parasite maintenance weekly program. I know for me it keeps the "gastritis problem" to a dull memory. I would also stress "wheat grass tablets" 4 before each meal. This keeps the blood sugar balanced and also gives energy.
I am taking my 1/4 tsp. of Poly everyday and feeling wonderful.
Using "Garden of Life" Primal Defense (acidophlis) daily.
Also, taking one of their multiple vitamins a day.
Taking 4 wheatgrass tablets with each meal and Coral Calcium.
Drinking a fruit smoothie and a vegi drink everyday.
Eating more vegetables than meat.
Making lots of soups with potatoes, chicken and turkey.
Try to have broth daily.
Our tap water in Tallahassee is good. No longer buying distilled water here, however, definitely buying when I travel. So, the bottom line is: With the Poly I am taking 2/3's less vitamin products than before. Therefore, the savings pays for the minimal dose of POLY. Remembering that, initially, I went on the full "Cancer" dosage for 10 weeks dropping down to 1tsp a day, to 1/2 and now 1/4. Thank you as always. It is wonderful to have "energy and health" after all these years of feeling physically trashed.
| 4.766253 | 0.652638 | -7.372698 | 0.513785 | 0.84951 | -6.015841 | -2.763878 | -0.440867 |
98,494 |
Armani announces a new fragrant pair and a new pillar of the Emporio Armani line which is supposed to represent "an olfactive embodiment of authentic modern-day love." The feminine edition Because It's You and the masculine Stronger With You. Top notes: raspberry, neroli. Heart: rose absolute. Base: vanilla, musk.
| 4.767967 | 0.199828 | -10.778476 | 0.294486 | 0.84652 | -3.285561 | -4.449649 | -0.79116 |
12,676 |
Petroleum is no less than gold and who knows it better than the Gulf nations. All thanks to its endless resources, the Gulf nations have witnessed a staggering growth since the last decade. This is why this place is a centre for many new businesses. As a result, there is a never-ending demand for manpower. And this is where the best gulf placement agencies in Mumbai are called up on stage.
Alliance Recruitment Agency is a top gulf consultancy in Mumbai. All thanks to our huge database, we cater to the needs of every business. The Gulf nations always have vacancies for various positions, including an accountant, doctor, security personnel, and chef. We have attained complete mastery in providing staffing solutions to every requirement of our partners.
As one of the top gulf recruitment agencies in Mumbai, we ensure that the candidates chosen by our recruiters go on to become the asset of their respective organisation.
The prosperity of Gulf nations provides a unique opportunity to the potential candidates to relocate to those nations and earn a fancy lifestyle with handsome salary. The recent trends suggest that more and more new businesses will call establish their business centres in the Gulf Nations – all thanks to its favourable financial condition.
Thus, the continuous demand for manpower has led to the growth of gulf consultancy in Mumbai. And we are definitely one of the best ones.
Dedicated Team – Our team is our biggest asset. Our team of recruiters pertain to the international standards and are handpicked and professionally trained. And the best thing is, our recruitment team consist of people from various backgrounds. Thus, we face no problem in catering to the needs of each of our clients.
Immense Experience – We are not new in the industry. We have been in the field of recruitment for quite some time now. We have years of expertise and it plays a huge role in recruiting the best talent.
International Connection: We firmly believe that geographical boundaries do not limit talent. And this is why we have established strong relationships with several other leading recruitment agencies worldwide. This is a win-win situation for both the parties as it presents a unique opportunity to share knowledge and resource.
Updated Technology: In the modern era, performing even the simplest task requires the use of technology. Any task without technological intervention is unthinkable. And we are in no mood to make the unthinkable happen. We make sure that we rely on the latest recruitment tools and software to shortlist the best talents.
Serving clients with passion and desire is our primary goal. They are pivotal for our stellar performance in the field of recruitment. Moreover, our portfolio separates us from other gulf placement agencies in Mumbai. We have had the privilege of serving some of the biggest organisations in the Gulf countries. We bet you won’t feel dissatisfied.
Today, we are regarded as one of the best gulf recruitment agencies in Mumbai and we aim to maintain that. We are never reluctant and our research and development team is always on action to ensure that we comply with the international standards by providing the best staffing solutions. Pricing is never an issue. As we guarantee, affordable services at a pocket-friendly price. So, get the best in the business without burning a hole in your pocket.
| -4.099986 | 0.766241 | -5.661246 | 0.594957 | 2.476754 | -7.064631 | -4.651935 | -0.633774 |
8,752 |
Call today, 201-654-0209, Bosch Nexxt repair to schedule a same day or next day appointment for a small diagnostic fee, cheaper than the industry average (Appliance Blue Book pricing) which goes toward the repair price. Have an experienced Bosch Nexxt technician service your appliance today 201-654-0209. All Bosch Nexxt appliance technicians have extensive experience servicing all types of appliances including Bosch Nexxt Refrigerator, Bosch Nexxt Oven, Bosch Nexxt Stove, Bosch Nexxt Washer, Bosch Nexxt Dryer, Bosch Nexxt Dishwasher, Bosch Nexxt Microwave, Bosch Nexxt Cooktop, Bosch Nexxt Freezer and Bosch Nexxt Ice Maker. Bosch Nexxt commercial appliance repair service as well. Same day appliance repair, Bosch Nexxt appliance installation, ac repair, offering best pricing, affordable pricing, emergency appliance repair and weekend repair. Call now 201-654-0209.
Call today, 201-654-0209, Bosch Nexxt repair to schedule a same day or next day appointment for a small diagnostic fee.
| -6.777847 | 0.388821 | -9.177035 | 0.016764 | 5.254196 | -7.576682 | -4.779513 | -1.167144 |
57,925 |
AltSys is a graphic design company established in Athens, Greece, in 1989. Since then we have designed, and in most cases fully prepared and printed, books and brochures, newsletters, leaflets, posters, print and outdoor ads, packaging, stands, logos, corporate identities and web sites. Our clients include museums, institutes, government services and law firms, as well as companies of different sizes and types, most of which have been trusting us for more than 15 years.
We are proud to collaborate with excellent associates working in various complementary areas (illustration, professional photography, colour separation, processing of photographs, printing and binding), all of whom give the final product the quality and touch we envisage for every product we design and supervise.
AltSys is owned and run by Ina Melengoglou, an English Literature graduate and graphic artist, who has personally designed most of the company’s projects and products. A few of the design works shown on this web site have been created by other graphic designers who either worked at or collaborated with AltSys at the time.
| 3.871233 | 0.768738 | -9.838736 | 0.966068 | 4.714552 | -7.247019 | -4.746204 | -0.544431 |
52,041 |
Blinds can be used in any room of the house - they are a great way to transform a room with better sun protection, blackout or just a splash of colour.With hundreds of blinds available, our partners even offer next day delivery to G17. If you're looking to buy a standard window blind, or a bespoke made to measure window blind, we can help. Add a splash of colour, find a blind that blends in - the choice is yours.
If you are buying made to measure blinds in G17 click on one of the images above. And if you don't see the type of product you need, then just click on the closest to find your way to the blinds that are exactly right for you in G17.
There are many tips for cleaning venetian window blinds but it's never a bad idea to check with the manufacturer who will know exactly the best approach. A damp cloth or sponge is usually the best answer to finger marks, and a quick vaccuum every week will keep them from collecting too much dust! Whatever type of blind you require, our partners can probably supply it not just to the colour and style you require, but often made to measure and delivered to G17.
This site is for blinds in G17. We offer a wide variety of wooden blinds, vertical blinds, roller blinds, venetian blinds, blackout blinds, panel blinds, velux blinds, roman blinds, and all can be made to measure for G17.
| 4.039079 | 0.935629 | -7.074892 | 1.108971 | 1.290512 | -5.345559 | -4.026743 | -0.206992 |
15,809 |
Indian Idol is one of the topmost rating TRP reality show. So many viewers like to see the daily updates of the show. On 23rd December 2018, there is the last and final day of the Indian Idol season 10. So as we all know that the winner should be selected on the basis of the highest vote. Salman Ali is one of the most favourite artist in the show Indian Idol 10.
There are so many guests are their in the show. The team of Zero is the part of the show Indian Idol 10 finale. They all are there for promoting the film. With, them there are two amazing ladies that are Shilpa Shetty and Choreographer Geeta Kapur will also be there for promoting the upcoming Kids’ dance reality TV series Super Dancer Chapter 3.
So here the suspense is over. Indian Idol season 10 gets the winner of the show. Salman Ali got the trophy of season 10 Indian Idol. The rest of the four contestants fighting for the winner’s title were Nitin Kumar, Ankush Bharadwaj, Neelanjana Ray and Vibhor Parashar. Judged by Neha Kakkar, Javed ALI AND Vishal Dadlani, the popular singing reality TV show premiered on July 29, 2018, on Sony TV.
She also said that Salman Ali fulfilled my wish of winning Indian Idol.
The top two finalists are Salman Ali and Ankush Bhardawaj.
The second runner-up of Indian Idol 10 is Neelanjana Ray.
The whole votes that Indian Idol contestants get that are 2.5 crore votes.
| -3.507708 | 1.128612 | -5.888241 | 1.108304 | 0.791925 | -6.000251 | -4.78498 | -0.36042 |
54,970 |
I love flannel and magnetic board materials. I’ve used them for LOTS of things. Here’s a set of Magnetic Flannel Board pieces of resources used by the early American colonists. Set them out for center play, group activities, and story telling. Students can learn to identify and label plants and animals. They can sort them, classify them, and talk about the pictures. They can manipulate them as they create stories and reports.
I LOVE them for prewriting activities. The kids work out all the story plots and twists before they ever begin to write. It makes for really well-developed writing projects (and you can print the images on plain paper for illustration purposes in class and student made books, if you wish)!
I liked to divide my classroom into all manner of nooks and crannies, so I used my file cabinets for walls between areas. That left the sides of the cabinets free for magnetic pictures and other magnetic manipulatives.
You can get magnetic paper at WalMart (R) and lots of places online for $1.00-$2.00 per page. It makes lovely copies and lasts a long time. I like to buy the professional quality in packs of 20 because they are less expensive per page, and much better quality paper.
If you don’t want to spend extra money on magnetic paper, run the items off on cover stock, laminate them, and add some sticky-back magnetic tape to the back. These are actually a lot easier to manipulate than the magnetic paper since they don’t stick flat to the surface.
You can also run them on canvas paper to use on flannel boards. The colors print brightly, and the rough backing of the canvas adheres perfectly to the flannel board.
However you choose to do it, download the FREE file, and let the fun begin!
You can find a complete set of games and activities about the natural resources used by the colonial settlers at Teachers Pay Teachers and Teacher’s Notebook. I hope you’ll find some things that will make learning fast, fun, and efficient!
How do you use magnetic paper?
Originally posted on November 11, 2012 on another website.
This entry was posted in Colonial America, Flannel Board, Integrated Instruction, Language Arts, Literacy Activities, Magnetic Board, Natural Resources, Plants, Thanksgiving, Thematic Teaching. Bookmark the permalink.
WOW! The material is really good for students n kids generally. Thank you Madame!
Thanks! I hope he has lots of fun with them. Do you have some of the same plants in Indonesia?
You’re most welcome, Madame! Yes, I do! Indonesia is tropical country.
| 4.760133 | 2.826241 | -3.020508 | 2.656586 | 2.1623 | 1.83236 | 3.51066 | 2.000511 |
78,428 |
These boots designed for the front have a new and improved design with an even closer contour fit, lightweight, and less bulk. Perforated neoprene to allow the leg to breath, releasing heat. Two strong “quick grip” closures make these boots easy to put on correctly every time and bell boots stay in place with cutback shape and “quick grip” tab. Fits like a second skin to protect your equine athlete while keeping the dirt out. Easy to clean. Sold in pairs.
best boots I have ever bought!! I have them for every horse I run barrels on..
Seems like good quality boots for a decent price.
Are these boots all one piece? Or is the sport boot and bell boot separate pieces?
BEST ANSWER: They are together, connected. To apply them it's best to loop all the velcro backwards onto the boot until it is placed onto the leg of the horse, then bring all the straps around. Kind of a pain but the velcro is good and sticky. Good product.
All in one. Not separate.
They are all one piece.
What size horse do the combo boots in medium fit? Thanks!
BEST ANSWER: They fit our 3yr quarter horse great she is probably medium build and they have been in my 16h gelding good size.
My horse is around 15 hands tall, she is a Tennessee Walking Horse and they work great for her. We love them.
They fit my quarter horse perfectly. Average horse size.
The mediums fit horses approximately 15 to 15.3 hands.
would a medium fit a 14 hands horse?
BEST ANSWER: Yes, per this size chart listed across from image the item med would be compatible for 15-15.3 hands.
Are the boots for hind legs?
BEST ANSWER: Combo boots are made for the front legs since they include bell boots which are used to keep the hind foot from hitting the front foot and removing a shoe or injuring the foot.
| 4.755073 | 1.121988 | -5.608795 | 1.187814 | 2.343713 | -5.130679 | -4.479446 | -0.006302 |
23,702 |
The Port of Ipswich has recently handled a large shipment containing 5000 t of imported road salt, to be used by Suffolk Highways to help make local roads safer.
By transporting this road salt as far as possible by sea, ABP has helped minimise the impact on the local road network and has ensured that Suffolk is prepared for any further cold weather conditions.
ABP took the opportunity to invite colleagues from Suffolk County Council including cabinet member councillor Mary Evans and members of the Suffolk gritting team to see the salt cargo arriving at the port.
Mark Stevens, Suffolk Highways’ assistant director, said: “Despite the weather gradually getting warmer, it is important to be prepared for every eventuality. This salt delivery has topped up our stock so that we can both effectively treat the roads as and when required, and continue to complement each other’s winter maintenance service.
Paul Ager, ABP divisional port manager, East Anglia, said: “We were delighted to work closely with Suffolk Highways and Suffolk County Council to ensure that we have sufficient product to ensure the ongoing safety of roads in our county, whatever the weather.
| 4.765221 | 1.572099 | -3.546957 | 1.643624 | 6.699232 | -5.001264 | -4.58418 | 0.503581 |
73,808 |
Stapleton Fan Club pre-sales will begin Tuesday, January 29 at 10:00am local time. For more information visit www.stapletonfanclub.com. Public tickets for the newly announced concerts begin Friday, February 1 at 10:00am local time at livenation.com, Ticketmaster, or by phone 800-745-3000. Live Nation is the official promoter of the All-American Road Show.
| 4.729319 | 0.127084 | -10.328054 | -0.095731 | 3.899155 | -8.150028 | -4.790528 | -1.134554 |
88,676 |
John Thomas Hancock, 56, of Danville PA went home to be with his Lord on Wednesday, December 6, 2017 in Danville. PA. He was born January 11, 1961 in Ashland PA, the son of the late John Patrick Hancock and Gertrude Marie Petruskevich Hancock of Mount Carmel PA.
He graduated from Mt. Carmel Area High School in 1979 and received his bachelor’s degree in Business Administration from Bloomsburg University in 1993.
John was married for 14 years to Lisa Bausch Hancock. They were married July 5, 2003.
He was the owner and plant manager of Pro-Corr, Inc. in Coal Township PA since 1993. He was self-employed as a Certified Personal Trainer for Know Kontrol in Danville PA for several years.
John was a member of First Baptist Church Danville PA where he served on the Board of Trustees, as an usher and enjoyed helping with Vacation Bible School.
John was a devoted husband and father. His quiet selflessness, dignity and servant heart will be missed greatly, as he holds a special place in the hearts of so many. John was dedicated to hard work and enjoyed hunting in his spare time. His greatest joy in life was spending time with his family whom he adored.
Services will be private and at the convenience of the family. Memorial contributions may be made to the American Heart Association online at www.heart.org or 5455 N. High Street Columbus OH 43214 or the Danville SPCA 2801 Bloom Road Danville PA 17821.
| 4.006974 | 0.566629 | -7.817213 | 0.388299 | 5.544665 | -6.187895 | -4.774855 | -0.562028 |
37,177 |
San Francisco Waterfront Development for Tourism Write a recommendation report in which you compare two potential river or seafront developments for one city with the intention of tourists.
3)Sustainability. Many of the city’s leading tourist attractions are located at the port, including Hyde Street Pier, Fisherman’s Wharf, PIER 39 and access to Alcatraz. These attractions draw more than 15 million visitors annually to San Francisco’s northern waterfront.
In addition to being a world-renowned visitor attraction, Fisherman’s Wharf is also the center of Northern California’s commercial fishing industry, Pier 45 is one of America’s most modern fish-processing centers.
| 4.767567 | 2.305157 | -4.757682 | 2.398206 | -0.677374 | -6.186228 | -4.649521 | 0.609106 |
66,755 |
At StartUp Assist startups, established companies and social organisations are connected. The aim is to share each other's expertise and network, to inspire each other and to learn from each other. Our motto: 'sports unites people'.
Internationaal zakendoen? Dat kan zo!
| 4.745092 | 0.541567 | -9.010336 | 1.073007 | -2.41876 | -4.078176 | -4.768946 | -0.504027 |
16,397 |
If you told me three-and-a-half years ago that I would soon become fairly obsessed with a hybrid storytelling-comedy podcast in which three brothers played a long form game of Dungeons & Dragons with their dad, I would’ve said… well, yeah, that sounds like me.
It’s not that I’m a die-hard Dungeons & Dragons fan—I’ve never even rolled a D20. But I have always loved the idea of the game—of a group of friends sitting around together, telling themselves a story.
It helped that the friends, in this particular case, are Justin, Travis, and Griffin McElroy, three guys I’d been listening to for years via their tongue-in-cheek advice podcast My Brother, My Brother, and Me, which is basically an hour of them trying to keep a comedy bit going for as long as they can until it stops being funny (or stops being funny and then becomes funny again). The idea of these good, good boys bringing the same wit and irreverence to a game of D&D—and with the help of their dad, Clint, a beloved background presence on MBMBaM and a professional radio personality—sounded irresistible.
And it was. And then it was more than that.
But even then, there were hints the show would turn out to be more than just a goof—Travis, the most experienced gamer of the bunch, had clearly put a lot of thought into the tragic backstory of his character, noble fighter Magnus Burnsides, and Griffin was already doing a lot of his own worldbuilding to layer atop the one found in the D&D starter set.
By the time the McElroys wrapped up the first campaign, in which Magnus, Merle, and Taako team up to infiltrate a cave teeming with goblins gerblins to recover a lost treasure that turns out to be a magical object of unspeakable power, the show had envolved into something strangely compelling—not quite a game of D&D, and not quite a comedy podcast, but something altogether new.
I liked it. So did other people. A lot of other people, many of them brilliantly talented artists who brought the characters to life in images shared on Tumblr and across social media (a bound collection of fan art, The Adventure Zine, was crowdsourced in order to raise money for charity).
For the next three years, TAZ’s community of online fans only grew alongside the narrative, which eventually became as layered as that of any television show or fantasy novel, with twists and turns and romances and reversals and so, so many endearing characters. Merle, Magnus, and Taako evolved from funny voices (or from the players forgetting to do their funny voices) delivering one-liners into real heroes with backstories that meant a lot to listeners—Merle’s struggles with his faith and a broken family, Taako’s guilt over past tragedies he had a hand in, Magnus’s ache at the loss of a partner. These three and so many other characters—the rest of them voiced by Griffin— built out a world trapped in the midst of an increasingly complex (and only occasionally convoluted) fantasy/space opera tale involving magic, revenge, the multiverse, and the bonds that endure beyond death.
It’s a really good podcast. You should listen to it. It will only take you about 75 hours. Once you’ve finished, you’ll want more. You certainly won’t want to let go of the world or the characters.
Fortunately, you no longer need to: The Adventure Zone is, of course, now more than a podcast. It’s also a graphic novel—hopefully, the first in a series of them; this volume covers the first campaign, Here There Be Gerblins, and a little extra, taking us through roughly episode seven of the show.
A podcast transitioning into a comic might sound odd (though there is precedent), but it isn’t too surprising, considering this is a fantasy story, and fantasy is all about making people imagine new worlds (hence all that fan art).
The thing is, it works quite brilliantly, whether you’re an existing fan of the podcast or not. A large part of its success has to do with the fact that it hews so closely to the show—its written by the four McElroys, who worked hand-in-hand with artist/co-writer Carey Pietsch—while also taking advantage of the comic book format. It’s not a straight adaptation so much as a reimagining of the story in a new medium, one that is very much about the visuals (it’s worth noting that Clint previously adapted films for comics, including just gems as Three Ninjas).
Griffin’s DM is still a presence, occasionally appearing in the corner of a panel to inject a bit of meta-humor: banter with the characters, remind them of the rules, or introduce a travel montage. The characters feel faithfully represented, perhaps even more so than they do in the actual episodes; at that point in the show, the players were still figuring things out, while the comic, written years into the run, benefits from hindsight. This also means there are plenty of opportunities for foreshadowing and in-jokes; the book definitely merits a close read or two to catch all the little details.
Carey Pietsch deserves special recognition for bringing to life a world that had already long flourished in listeners’ minds, as well as in countless pieces of fan art. While the McElroys have been canny about stating that there is no official “canon” version of the characters and that the comic simply presents one interpretation, there’s also never a point in the graphic novel that any of the characters—from the three adventurers, to countless gerblins, to effete dark wizard Magic Brian—look like anything but themselves. Even better, Pietsch shows remarkable skill at depicting humor and action with an economy of panels; fans know the ending of this campaign is fairly epic, and the book nails the visuals (Taako’s famed “Abraca-f***-you!” moment is rendered suitable for framing).
It’s hard to overstate the appeal of The Adventure Zone; as evidenced by the size and volume of its fanbase (and when I say “volume,” I’m speaking literally, as I’ve attended one of their live shows). That it is fun and funny is expected (it’s practically baked into the premise), but I’m in awe of what it accomplished in terms of long-form SFF storytelling (I’m not alone: no less an august fantasy personage than Patrick “Kingkiller Chronicles” Rothfuss provides an introduction to this volume). And if there’s any format that does long-form storytelling well, it’s comics.
I’m ready for the next campaign. Let’s roll for initiative.
The Adventure Zone: Here There Be Gerblins is available July 17. The Barnes & Noble edition includes an exclusive variant cover and two-sided poster.
| 4.251155 | 0.847745 | -4.556966 | 0.682769 | 6.122624 | -3.384506 | -4.694792 | 0.00446 |
18,097 |
Providing great efficiency and utility! All of the following features are included: variably intermittent wipers, remote keyless entry, and 1-touch window functionality. Performance and efficiency are both prioritized thanks to the efficient 4 cylinder engine, and for added security, dynamic Stability Control supplements the drivetrain. Both high fuel economy and flexible performance are assured by the 6 speed automatic transmission.
| 4.768745 | 0.554651 | -9.967043 | 0.796536 | -2.715995 | 0.932108 | -4.151101 | -0.306239 |
42,399 |
Soon to be father, Sunny Chan Kam Hung revealed in a radio interview that the baby’s due date will be May 2nd. "The baby should be a boy, but I am happy whether it is a boy or girl. The baby’s name will be decided by a Chinese teacher. But for now we plan to call him Hung Jai."
To help his wife lose post-pregnancy weight, Sunny has already designed a special menu for her.
Sunny also revealed that he terminated his restaurant business last month. "The landlord increased the rent by 30%, thus I decided to sell the business instead." Sunny earned a good profit from the sale.
| 4.765726 | 0.504432 | -8.307328 | 0.396311 | 4.708989 | -10.603045 | -4.773738 | -0.877256 |
1,671 |
FORT CAMPBELL, Ky. -- On Tuesday, hundreds of soldiers returned home from a nine-month deployment in Afghanistan.
"It's excitement (and) nervousness because you never know how the children are going to react, but overall just a lot of excitement," said Lindsay Dunne.
Lindsay Dunne, and her two boys were waiting for their soldier to get off the plane and march into the hangar, "The boys were yelling and screaming and I was looking for him."
Gail Mintz was there to find her little cousin Keandre Corizine, "It feels amazing. We are just glad they all made it back safely."
This was Corizine's first deployment. He says although he got used to being away, there is no feeling like coming home, "New experience being away from family, but I was adapting and adjusting to most things. Dealing with the heat and the workouts was pretty tough some days but, you know just brush it off."
For fifteen minutes, before leaving briefly to return their gear, these soldiers were holding their loved ones tight. Kevin O'Malley spent those minutes meeting his son for the first time, "Its been a long nine months or so but I'm just happy to be home."
After a 12-hour flight and an emotional reunion soldiers like Joseph Dunne are ready to head home, "I was excited to see them. I was ready to get all this over with so we can go home and see each other."
During this deployment, the 101st Combat Aviation Brigade provided aviation support to U.S. coalition and Afghan forces.
In February, 700 soldiers will return home to Fort Campbell.
| 4.764181 | 1.531635 | -5.824559 | 1.207019 | 5.693578 | -4.192149 | -4.779023 | 0.236761 |
34,431 |
Is anyone else having trouble with some of the games playing very slowly, or too slow to even play? Picture Pieces is very slow as are some others, can’t even play Space Hunt. I can’t get live stream to watch HSN while in the arcade at all, this is the third day. I have cleared cache, and the other games are fine.
I haven’t been able to get Tripeaks Solitaire to load in iPad for days now. HSN advised they are working on resolving issue as a result of an iOS update.
This reply was modified 2 years ago by Nyer514.
Games Not Working at all for me!!! They won’t come up on screen when touched! Guess I don’t get to play for double tickets fewey!!!!
It sounds like you are trying to play on a tablet or phone. Try reinstalling the HSN app. If that doesn’t work, try a different browser.
@myra1 I’m not having that problem. I forget whether you are using Windows or Apple and what browser. I have been using Win7 with Chrome because it updates Adobe Flash automatically. For some reason months ago it became a real chore to update AdobeFlash with Internet Explorer–it changed from how I used to be able to do it.
Once in awhile a game will seem to run more slowly if I’ve been playing it a lot. If I close the tab and open a new one to play the game, it gets better.
When I had trouble with the games or the live streaming it had to do with needing to update Flash. Sometimes it had to do with Adobe Shockwave–abling or disabling it seemed to help sometimes. It seemed like just changing it from what it was made a difference.
I take it that you have run a Scan. Sometimes just Restarting the Computer gets rid of ‘bugs’.
| 4.764359 | 0.626989 | -7.585736 | 0.336324 | -3.845615 | -3.704724 | -4.753276 | -0.614162 |
32,957 |
"Cni-Novell Edirectory Design And Implemenation", also known as 050-864-(575B) exam, is a Novell Certification. With the complete collection of questions and answers, Prep4cert has assembled to take you through 128 Q&As to your 050-864-(575B) Exam preparation. In the 050-864-(575B) exam resources, you will cover every field and category in Novell Novell Certification helping to ready you for your successful Novell Certification.
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| 4.756721 | 1.111316 | -3.416618 | 1.430511 | 1.15917 | -4.743276 | -4.295604 | 0.199192 |
67,608 |
AMP Plugin powered WordPress – well that’s annoying isn’t it for your Accelerated Mobile Pages.
After getting AMP working on your site those helpful folks over at Automatic decide to create a link back to WordPress.
That’s it – you are done.
| 1.421787 | 0.028894 | -11.34207 | 0.144174 | 0.347369 | -9.39949 | -4.772611 | -1.405497 |
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