subject
stringlengths 75
97
| txt_report
stringlengths 1.31k
2.78k
| gold_diagnosis
stringclasses 5
values |
|---|---|---|
NIFD_1_S_0097_MR_T1_mprage_S3_DIS3D_br_raw_20120819171037400_152_S161488_I324741_dupl_4 | On a T1-weighted brain MRI of a 69-year-old male subject, we observed:
For the cerebral cortex:
- no observable atrophic alterations in the occipital lobe
- no signs of atrophy detected in the frontal lobe
- parietal lobe appears structurally intact with no atrophic changes
- severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (between moderate and severe), planum polare (between normal and mild), inf. temporal gyrus (severe), middle temporal gyrus (severe), sup. temporal gyrus (mild) and temporal pole (severe)
- insular cortex maintains its normal morphology without atrophic features
- mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (severe) and parahippocampal gyrus (moderate)
For the subcortical structures:
- no signs of atrophy detected in the ventral dc
- mild right atrophy of the putamen
- no degenerative or atrophic changes noted in the basal forebrain
- severe bilateral accumbens atrophy, more pronounced on the right
- thalamus remains normal, with no signs of tissue loss
- moderate bilateral hippocampus atrophy, more pronounced on the right
- no signs of atrophy detected in the pallidum
- between normal and mild atrophy of the caudate, more pronounced on the right
- severe bilateral amygdala atrophy, more pronounced on the right
For the ventricles:
- lateral ventricle is free from enlargement or excessive growth
- between normal and mild enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- 4th ventricle maintains its normal volume without signs of enlargement | SV |
NIFD_3_S_0008_MR_T1_mprage_ND_br_raw_20160518225653834_34_S442955_I709965_dupl_5 | On a T1-weighted brain MRI of a 76-year-old male subject, we observed:
For the subcortical structures:
- between mild and moderate atrophy of the pallidum, more pronounced on the left
- the hippocampus shows no structural abnormalities indicative of atrophy
- between normal and mild atrophy of the caudate, more pronounced on the left
- between normal and mild atrophy of the thalamus, more pronounced on the left
- the amygdala shows no structural abnormalities indicative of atrophy
- between normal and mild left atrophy of the putamen
- basal forebrain appears structurally intact with no atrophic changes
- between normal and mild atrophy of the accumbens, more pronounced on the left
- moderate bilateral ventral dc atrophy, more pronounced on the left
For the cerebral cortex:
- no observable atrophic alterations in the occipital lobe
- no evidence of atrophy or degeneration in the parietal lobe
- the temporal lobe shows no structural abnormalities indicative of atrophy
- mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (between mild and moderate), precentral gyrus (moderate) and sup. frontal gyrus (mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (between normal and mild) and frontal operculum (moderate)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (mild) and posterior cingulate gyrus (mild)
For the ventricles:
- inf. lateral ventricle is free from enlargement or excessive growth
- between normal and mild enlargement of the lateral ventricle, more pronounced on the left
- between moderate and severe enlargement of the 4th ventricle
- between mild and moderate enlargement of the 3rd ventricle
- no observable enlargement or abnormal growth in the external csf | PNFA |
ADNI_037_S_5162_MR_MPRAGE_br_raw_20130503091904515_4_S188623_I369977_dupl_5 | On a T1-weighted brain MRI of a 70-year-old male subject, we observed:
For the cerebral cortex:
- no signs of atrophy detected in the parietal lobe
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (between normal and mild), orbital inf. frontal gyrus (mild) and posterior orbital gyrus (mild)
- limbic cortex maintains its normal morphology without atrophic features
- no observable atrophic alterations in the occipital lobe
- between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (between mild and moderate)
- between normal and mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (between normal and mild) and middle temporal gyrus (between normal and mild)
For the ventricles:
- no observable enlargement or abnormal growth in the lateral ventricle
- external csf maintains its normal volume without signs of enlargement
- 4th ventricle is free from enlargement or excessive growth
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- between normal and mild enlargement of the 3rd ventricle
For the subcortical structures:
- the ventral dc shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the thalamus
- no pathological changes consistent with atrophy detected in the pallidum
- the basal forebrain shows no structural abnormalities indicative of atrophy
- between normal and mild right atrophy of the caudate
- between normal and mild right atrophy of the amygdala
- hippocampus maintains its normal morphology without atrophic features
- between normal and mild left atrophy of the putamen
- the accumbens shows no structural abnormalities indicative of atrophy | AD |
ADNI_003_S_4142_MR_Accelerated_SAG_IR-SPGR__br_raw_20110906152028494_176_S121316_I254890_dupl_5 | On a T1-weighted brain MRI of a 90-year-old female subject, we observed:
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in triangular inf. frontal gyrus (between normal and mild), medial frontal cortex (between mild and moderate), supplementary motor cortex (between normal and mild) and gyrus rectus (mild)
- no observable atrophic alterations in the insular cortex
- occipital lobe maintains its normal morphology without atrophic features
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (between mild and moderate) and transverse temporal gyrus (between mild and moderate)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (between mild and moderate) and posterior cingulate gyrus (severe)
- parietal lobe appears structurally intact with no atrophic changes
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the amygdala
- between normal and mild left atrophy of the ventral dc
- caudate remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the accumbens
- between normal and mild left atrophy of the basal forebrain
- thalamus maintains its normal morphology without atrophic features
- no observable atrophic alterations in the putamen
- no evidence of atrophy or degeneration in the pallidum
- hippocampus presents with a healthy appearance, free from atrophy
For the ventricles:
- 4th ventricle appears structurally intact, with no evidence of enlargement
- no signs of enlargement detected in the external csf
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- lateral ventricle is free from enlargement or excessive growth
- no abnormal enlargement observed in the inf. lateral ventricle | AD |
ADNI_128_S_4832_MR_MPRAGE_br_raw_20120710092632233_36_S157109_I315671_dupl_1 | On a T1-weighted brain MRI of a 70-year-old male subject, we observed:
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (mild), lateral orbital gyrus (moderate), medial orbital gyrus (between normal and mild) and precentral gyrus medial segment (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in fusiform gyrus (between normal and mild), planum temporale (between normal and mild) and transverse temporal gyrus (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (mild) and occipital pole (between normal and mild)
- no degenerative or atrophic changes noted in the limbic cortex
- parietal lobe appears structurally intact with no atrophic changes
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal operculum (between normal and mild) and parietal operculum (between normal and mild)
For the subcortical structures:
- putamen presents with a healthy appearance, free from atrophy
- ventral dc appears structurally intact with no atrophic changes
- no observable atrophic alterations in the hippocampus
- no signs of atrophy detected in the basal forebrain
- caudate remains normal, with no signs of tissue loss
- the thalamus shows no structural abnormalities indicative of atrophy
- accumbens presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the amygdala
- pallidum appears structurally intact with no atrophic changes
For the ventricles:
- 3rd ventricle maintains its normal volume without signs of enlargement
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- no abnormal enlargement observed in the 4th ventricle
- lateral ventricle is free from enlargement or excessive growth
- no enlargement observed in the external csf | CN |
ADNI_135_S_5015_MR_MPRAGE_br_raw_20121113152042237_162_S174375_I346353_dupl_5 | On a T1-weighted brain MRI of a 78-year-old female subject, we observed:
For the subcortical structures:
- hippocampus appears structurally intact with no atrophic changes
- putamen presents with a healthy appearance, free from atrophy
- between normal and mild left atrophy of the amygdala
- between normal and mild right atrophy of the thalamus
- caudate appears structurally intact with no atrophic changes
- moderate bilateral accumbens atrophy
- no evidence of atrophy or degeneration in the basal forebrain
- no pathological changes consistent with atrophy detected in the pallidum
- no evidence of atrophy or degeneration in the ventral dc
For the ventricles:
- no observable enlargement or abnormal growth in the lateral ventricle
- mild enlargement of the 3rd ventricle
- mild bilateral inf. lateral ventricle enlargement
- the external csf shows no structural abnormalities indicative of enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected
For the cerebral cortex:
- parietal lobe appears structurally intact with no atrophic changes
- the occipital lobe shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the temporal lobe
- no observable atrophic alterations in the limbic cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (between mild and moderate), anterior orbital gyrus (between normal and mild) and supplementary motor cortex (mild)
- no pathological changes consistent with atrophy detected in the insular cortex | AD |
ADNI_024_S_4280_MR_MPRAGE_br_raw_20111018163207473_117_S125582_I261332_dupl_5 | On a T1-weighted brain MRI of a 80-year-old male subject, we observed:
For the ventricles:
- no enlargement observed in the inf. lateral ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
- no enlargement observed in the lateral ventricle
- 3rd ventricle maintains its normal volume without signs of enlargement
- moderate enlargement of the external csf
For the subcortical structures:
- between normal and mild left atrophy of the thalamus
- severe bilateral amygdala atrophy, more pronounced on the right
- no signs of atrophy detected in the putamen
- between moderate and severe bilateral hippocampus atrophy
- the ventral dc shows no structural abnormalities indicative of atrophy
- basal forebrain appears structurally intact with no atrophic changes
- no signs of atrophy detected in the caudate
- accumbens maintains its normal morphology without atrophic features
- pallidum appears structurally intact with no atrophic changes
For the cerebral cortex:
- the occipital lobe shows no structural abnormalities indicative of atrophy
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (between normal and mild), transverse temporal gyrus (between normal and mild) and temporal pole (between normal and mild)
- mild atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: entorhinal area (mild) and parahippocampal gyrus (mild)
- no degenerative or atrophic changes noted in the parietal lobe
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal pole (between normal and mild) and posterior orbital gyrus (moderate)
- no signs of atrophy detected in the insular cortex | AD |
ADNI_136_S_4993_MR_MPRAGE_br_raw_20121025150812723_51_S172271_I342522_dupl_4 | On a T1-weighted brain MRI of a 72-year-old female subject, we observed:
For the cerebral cortex:
- the temporal lobe shows no structural abnormalities indicative of atrophy
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parietal operculum (between normal and mild) and central operculum (between normal and mild)
- parietal lobe remains normal, with no signs of tissue loss
- limbic cortex remains normal, with no signs of tissue loss
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (mild), lateral orbital gyrus (between normal and mild) and precentral gyrus medial segment (between normal and mild)
- no pathological changes consistent with atrophy detected in the occipital lobe
For the ventricles:
- lateral ventricle is free from enlargement or excessive growth
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- no signs of enlargement detected in the external csf
- 4th ventricle is free from enlargement or excessive growth
- mild enlargement of the inf. lateral ventricle, more pronounced on the left
For the subcortical structures:
- between normal and mild left atrophy of the thalamus
- between normal and mild left atrophy of the basal forebrain
- the pallidum shows no structural abnormalities indicative of atrophy
- hippocampus presents with a healthy appearance, free from atrophy
- putamen maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the accumbens
- amygdala appears structurally intact with no atrophic changes
- ventral dc maintains its normal morphology without atrophic features
- caudate maintains its normal morphology without atrophic features | AD |
ADNI_016_S_5057_MR_Accelerated_SAG_IR-SPGR__br_raw_20130226082518326_195_S183095_I361230_dupl_4 | On a T1-weighted brain MRI of a 75-year-old male subject, we observed:
For the subcortical structures:
- pallidum presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the putamen
- accumbens maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the ventral dc
- no observable atrophic alterations in the thalamus
- amygdala remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the caudate
- hippocampus maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the basal forebrain
For the cerebral cortex:
- limbic cortex remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the parietal lobe
- no signs of atrophy detected in the insular cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (between normal and mild) and anterior orbital gyrus (between normal and mild)
- occipital lobe maintains its normal morphology without atrophic features
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. temporal gyrus (between normal and mild) and planum temporale (between normal and mild)
For the ventricles:
- lateral ventricle is free from enlargement or excessive growth
- 3rd ventricle is free from enlargement or excessive growth
- no abnormal enlargement observed in the 4th ventricle
- between moderate and severe bilateral inf. lateral ventricle enlargement
- no signs of enlargement detected in the external csf | AD |
NIFD_1_S_0339_MR_T1_mprage_S3_DIS3D_br_raw_20170629002457144_144_S577807_I867541_dupl_5 | On a T1-weighted brain MRI of a 63-year-old female subject, we observed:
For the subcortical structures:
- severe bilateral accumbens atrophy, more pronounced on the right
- between normal and mild atrophy of the putamen, more pronounced on the right
- severe bilateral hippocampus atrophy, more pronounced on the right
- thalamus remains normal, with no signs of tissue loss
- between normal and mild right atrophy of the caudate
- severe bilateral amygdala atrophy, more pronounced on the right
- no degenerative or atrophic changes noted in the basal forebrain
- ventral dc appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the pallidum
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (mild), medial orbital gyrus (between mild and moderate) and medial frontal cortex (mild)
- occipital lobe remains normal, with no signs of tissue loss
- moderate bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate), central operculum (mild) and parietal operculum (between normal and mild)
- moderate bilateral limbic cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: entorhinal area (mild), anterior cingulate gyrus (moderate) and parahippocampal gyrus (between normal and mild)
- parietal lobe maintains its normal morphology without atrophic features
- severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), planum polare (between normal and mild), planum temporale (between normal and mild), inf. temporal gyrus (between moderate and severe), sup. temporal gyrus (between mild and moderate), temporal pole (severe) and middle temporal gyrus (mild)
For the ventricles:
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- no abnormal enlargement observed in the lateral ventricle
- mild enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement
- no observable enlargement or abnormal growth in the 4th ventricle | SV |
NIFD_1_S_0269_MR_t1_mprage__br_raw_20160902220526927_82_S496410_I772673_dupl_3 | On a T1-weighted brain MRI of a 63-year-old female subject, we observed:
For the cerebral cortex:
- parietal lobe maintains its normal morphology without atrophic features
- temporal lobe presents with a healthy appearance, free from atrophy
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between mild and moderate) and middle cingulate gyrus (between normal and mild)
- insular cortex presents with a healthy appearance, free from atrophy
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (between normal and mild) and occipital fusiform gyrus (between mild and moderate)
- frontal lobe appears structurally intact with no atrophic changes
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the amygdala
- the basal forebrain shows no structural abnormalities indicative of atrophy
- between normal and mild left atrophy of the thalamus
- pallidum presents with a healthy appearance, free from atrophy
- between normal and mild left atrophy of the putamen
- no observable atrophic alterations in the caudate
- no evidence of atrophy or degeneration in the hippocampus
- mild bilateral accumbens atrophy, more pronounced on the right
- no observable atrophic alterations in the ventral dc
For the ventricles:
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- lateral ventricle appears structurally intact, with no evidence of enlargement
- no abnormal enlargement observed in the 4th ventricle
- between normal and mild enlargement of the external csf
- 3rd ventricle is free from enlargement or excessive growth | CN |
NIFD_1_S_0175_MR_T1_mprage_S3_DIS3D_br_raw_20140701125948453_146_S223924_I434014_dupl_3 | On a T1-weighted brain MRI of a 60-year-old female subject, we observed:
For the ventricles:
- between normal and mild enlargement of the 3rd ventricle
- lateral ventricle is free from enlargement or excessive growth
- the external csf shows no structural abnormalities indicative of enlargement
- no signs of enlargement detected in the inf. lateral ventricle
- no enlargement observed in the 4th ventricle
For the subcortical structures:
- no signs of atrophy detected in the basal forebrain
- no signs of atrophy detected in the caudate
- between normal and mild bilateral hippocampus atrophy
- no evidence of atrophy or degeneration in the ventral dc
- no evidence of atrophy or degeneration in the pallidum
- no observable atrophic alterations in the amygdala
- the accumbens shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the thalamus
- no pathological changes consistent with atrophy detected in the putamen
For the cerebral cortex:
- no observable atrophic alterations in the parietal lobe
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (mild) and frontal operculum (between normal and mild)
- no pathological changes consistent with atrophy detected in the limbic cortex
- occipital lobe presents with a healthy appearance, free from atrophy
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (between normal and mild) and anterior orbital gyrus (between normal and mild)
- temporal lobe maintains its normal morphology without atrophic features | CN |
ADNI_070_S_4719_MR_MPRAGE_br_raw_20120521142246850_171_S151143_I305573_dupl_1 | On a T1-weighted brain MRI of a 80-year-old female subject, we observed:
For the ventricles:
- between normal and mild enlargement of the inf. lateral ventricle, more pronounced on the left
- no signs of enlargement detected in the 3rd ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
- between normal and mild enlargement of the external csf
- lateral ventricle remains within normal size parameters, with no enlargement detected
For the cerebral cortex:
- the occipital lobe shows no structural abnormalities indicative of atrophy
- mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: posterior cingulate gyrus (between mild and moderate) and parahippocampal gyrus (between moderate and severe)
- no signs of atrophy detected in the insular cortex
- between moderate and severe bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: fusiform gyrus (between mild and moderate), planum temporale (mild), sup. temporal gyrus (mild) and temporal pole (mild)
- the frontal lobe shows no structural abnormalities indicative of atrophy
- mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: postcentral gyrus (mild), precuneus (mild) and sup. parietal lobule (mild)
For the subcortical structures:
- basal forebrain maintains its normal morphology without atrophic features
- ventral dc remains normal, with no signs of tissue loss
- moderate atrophy of the amygdala, more pronounced on the left
- no signs of atrophy detected in the caudate
- between mild and moderate atrophy of the hippocampus, more pronounced on the left
- no evidence of atrophy or degeneration in the thalamus
- no evidence of atrophy or degeneration in the accumbens
- no evidence of atrophy or degeneration in the pallidum
- no degenerative or atrophic changes noted in the putamen | AD |
NIFD_1_S_0237_MR_t1_mprage__br_raw_20160902142657075_120_S495712_I771873_dupl_5 | On a T1-weighted brain MRI of a 68-year-old female subject, we observed:
For the cerebral cortex:
- frontal lobe remains normal, with no signs of tissue loss
- insular cortex maintains its normal morphology without atrophic features
- temporal lobe maintains its normal morphology without atrophic features
- the limbic cortex shows no structural abnormalities indicative of atrophy
- between mild and moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild) and precuneus (mild)
- no signs of atrophy detected in the occipital lobe
For the ventricles:
- no enlargement observed in the lateral ventricle
- no signs of enlargement detected in the external csf
- 3rd ventricle maintains its normal volume without signs of enlargement
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the 4th ventricle
For the subcortical structures:
- no observable atrophic alterations in the hippocampus
- no observable atrophic alterations in the basal forebrain
- no degenerative or atrophic changes noted in the amygdala
- no evidence of atrophy or degeneration in the ventral dc
- the putamen shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the caudate
- thalamus appears structurally intact with no atrophic changes
- pallidum presents with a healthy appearance, free from atrophy
- between normal and mild atrophy of the accumbens, more pronounced on the right | CN |
ADNI_003_S_5187_MR_Accelerated_SAG_IR-SPGR__br_raw_20130610202342271_157_S191910_I375951_dupl_1 | On a T1-weighted brain MRI of a 62-year-old female subject, we observed:
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (mild), occipital fusiform gyrus (mild), sup. occipital gyrus (mild) and occipital pole (mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in fusiform gyrus (between normal and mild), planum temporale (mild) and transverse temporal gyrus (between normal and mild)
- the insular cortex shows no structural abnormalities indicative of atrophy
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus medial segment (between normal and mild) and sup. frontal gyrus medial segment (between normal and mild)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precuneus (mild) and sup. parietal lobule (between normal and mild)
- limbic cortex appears structurally intact with no atrophic changes
For the ventricles:
- 4th ventricle is free from enlargement or excessive growth
- between normal and mild enlargement of the external csf
- between normal and mild enlargement of the lateral ventricle
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- between normal and mild right enlargement of the inf. lateral ventricle
For the subcortical structures:
- between moderate and severe bilateral amygdala atrophy
- putamen remains normal, with no signs of tissue loss
- thalamus presents with a healthy appearance, free from atrophy
- severe bilateral hippocampus atrophy
- ventral dc remains normal, with no signs of tissue loss
- the accumbens shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the basal forebrain
- no observable atrophic alterations in the pallidum
- caudate presents with a healthy appearance, free from atrophy | AD |
NIFD_2_S_0027_MR_MT1__GradWarp__N3m_Br_20130103113648528_S177998_I353170_dupl_3 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the subcortical structures:
- severe bilateral hippocampus atrophy, more pronounced on the left
- mild bilateral pallidum atrophy
- between mild and moderate bilateral accumbens atrophy, more pronounced on the right
- basal forebrain presents with a healthy appearance, free from atrophy
- between normal and mild atrophy of the caudate
- no observable atrophic alterations in the ventral dc
- thalamus appears structurally intact with no atrophic changes
- severe bilateral amygdala atrophy
- mild bilateral putamen atrophy
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the parietal lobe
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (mild), planum polare (between normal and mild), middle temporal gyrus (between mild and moderate), sup. temporal gyrus (between normal and mild) and temporal pole (severe)
- mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (between moderate and severe) and posterior insula (between normal and mild)
- no pathological changes consistent with atrophy detected in the occipital lobe
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between moderate and severe) and parahippocampal gyrus (moderate)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lateral orbital gyrus (mild), gyrus rectus (between normal and mild) and opercular inf. frontal gyrus (between normal and mild)
For the ventricles:
- between moderate and severe enlargement of the external csf
- no signs of enlargement detected in the 3rd ventricle
- no signs of enlargement detected in the lateral ventricle
- between normal and mild left enlargement of the inf. lateral ventricle
- 4th ventricle maintains its normal volume without signs of enlargement | BV |
NIFD_1_S_0194_MR_T1_mprage_S3_DIS3D_br_raw_20140831195557073_107_S229201_I441537_dupl_1 | On a T1-weighted brain MRI of a 77-year-old female subject, we observed:
For the cerebral cortex:
- between moderate and severe atrophy of the insular cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (mild), central operculum (between mild and moderate), parietal operculum (moderate) and posterior insula (severe)
- no pathological changes consistent with atrophy detected in the frontal lobe
- limbic cortex remains normal, with no signs of tissue loss
- mild bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: planum temporale (moderate), inf. temporal gyrus (mild), sup. temporal gyrus (between normal and mild) and transverse temporal gyrus (between mild and moderate)
- occipital lobe remains normal, with no signs of tissue loss
- between mild and moderate atrophy of the parietal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: precuneus (between normal and mild), sup. parietal lobule (between normal and mild) and angular gyrus (mild)
For the subcortical structures:
- accumbens maintains its normal morphology without atrophic features
- between normal and mild right atrophy of the pallidum
- basal forebrain presents with a healthy appearance, free from atrophy
- between mild and moderate bilateral putamen atrophy, more pronounced on the right
- no pathological changes consistent with atrophy detected in the thalamus
- no signs of atrophy detected in the ventral dc
- amygdala presents with a healthy appearance, free from atrophy
- between normal and mild right atrophy of the caudate
- no evidence of atrophy or degeneration in the hippocampus
For the ventricles:
- no pathological changes consistent with enlargement noted in the 4th ventricle
- no pathological changes consistent with enlargement noted in the lateral ventricle
- inf. lateral ventricle is free from enlargement or excessive growth
- no abnormal enlargement observed in the 3rd ventricle
- mild enlargement of the external csf | PNFA |
NIFD_1_S_0072_MR_T1_mprage_S3_DIS3D_br_raw_20170816175300325_153_S597008_I890174_dupl_3 | On a T1-weighted brain MRI of a 69-year-old male subject, we observed:
For the ventricles:
- moderate enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- lateral ventricle appears structurally intact, with no evidence of enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected
- 3rd ventricle remains within normal size parameters, with no enlargement detected
For the subcortical structures:
- between normal and mild atrophy of the pallidum, more pronounced on the left
- between moderate and severe bilateral accumbens atrophy, more pronounced on the left
- the caudate shows no structural abnormalities indicative of atrophy
- between mild and moderate atrophy of the putamen, more pronounced on the left
- severe bilateral hippocampus atrophy, more pronounced on the left
- between normal and mild atrophy of the thalamus, more pronounced on the left
- ventral dc presents with a healthy appearance, free from atrophy
- the basal forebrain shows no structural abnormalities indicative of atrophy
- severe bilateral amygdala atrophy, more pronounced on the left
For the cerebral cortex:
- no observable atrophic alterations in the occipital lobe
- between moderate and severe bilateral insular cortex atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: anterior insula (between moderate and severe), posterior insula (between mild and moderate) and parietal operculum (mild)
- parietal lobe maintains its normal morphology without atrophic features
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior orbital gyrus (moderate) and sup. frontal gyrus medial segment (between normal and mild)
- severe bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), planum temporale (between mild and moderate), inf. temporal gyrus (severe), middle temporal gyrus (severe), sup. temporal gyrus (mild) and temporal pole (severe)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (severe) and parahippocampal gyrus (severe) | SV |
ADNI_019_S_4477_MR_MPRAGE_br_raw_20120126085251352_103_S138533_I280783_dupl_3 | On a T1-weighted brain MRI of a 83-year-old female subject, we observed:
For the ventricles:
- between mild and moderate enlargement of the external csf
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- between normal and mild enlargement of the inf. lateral ventricle
- 4th ventricle remains within normal size parameters, with no enlargement detected
- lateral ventricle remains within normal size parameters, with no enlargement detected
For the cerebral cortex:
- mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between normal and mild) and anterior cingulate gyrus (mild)
- temporal lobe remains normal, with no signs of tissue loss
- mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus medial segment (between normal and mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior insula (between normal and mild) and parietal operculum (between normal and mild)
- between normal and mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild), medial frontal cortex (between mild and moderate) and sup. frontal gyrus (between normal and mild)
- no degenerative or atrophic changes noted in the occipital lobe
For the subcortical structures:
- no observable atrophic alterations in the ventral dc
- moderate bilateral accumbens atrophy, more pronounced on the right
- between mild and moderate bilateral amygdala atrophy
- thalamus remains normal, with no signs of tissue loss
- moderate bilateral hippocampus atrophy
- between normal and mild left atrophy of the caudate
- pallidum remains normal, with no signs of tissue loss
- the putamen shows no structural abnormalities indicative of atrophy
- basal forebrain presents with a healthy appearance, free from atrophy | AD |
ADNI_018_S_5240_MR_MPRAGE_br_raw_20130723160412209_118_S196225_I382181_dupl_3 | On a T1-weighted brain MRI of a 63-year-old female subject, we observed:
For the subcortical structures:
- no observable atrophic alterations in the accumbens
- basal forebrain appears structurally intact with no atrophic changes
- no observable atrophic alterations in the thalamus
- putamen remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the pallidum
- the amygdala shows no structural abnormalities indicative of atrophy
- hippocampus remains normal, with no signs of tissue loss
- the caudate shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the ventral dc
For the cerebral cortex:
- no evidence of atrophy or degeneration in the limbic cortex
- frontal lobe remains normal, with no signs of tissue loss
- temporal lobe appears structurally intact with no atrophic changes
- no signs of atrophy detected in the insular cortex
- no pathological changes consistent with atrophy detected in the occipital lobe
- no evidence of atrophy or degeneration in the parietal lobe
For the ventricles:
- external csf maintains its normal volume without signs of enlargement
- lateral ventricle maintains its normal volume without signs of enlargement
- no enlargement observed in the 3rd ventricle
- no abnormal enlargement observed in the 4th ventricle
- no signs of enlargement detected in the inf. lateral ventricle | AD |
NIFD_1_S_0273_MR_t1_mprage_short__br_raw_20160903183136298_99_S496584_I772871_dupl_3 | On a T1-weighted brain MRI of a 67-year-old female subject, we observed:
For the ventricles:
- no enlargement observed in the inf. lateral ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
- no signs of enlargement detected in the 4th ventricle
- no enlargement observed in the 3rd ventricle
- between normal and mild enlargement of the external csf
For the subcortical structures:
- no degenerative or atrophic changes noted in the ventral dc
- mild right atrophy of the hippocampus
- no degenerative or atrophic changes noted in the accumbens
- thalamus remains normal, with no signs of tissue loss
- between normal and mild bilateral putamen atrophy
- no signs of atrophy detected in the basal forebrain
- pallidum appears structurally intact with no atrophic changes
- mild right atrophy of the amygdala
- no observable atrophic alterations in the caudate
For the cerebral cortex:
- no observable atrophic alterations in the insular cortex
- no pathological changes consistent with atrophy detected in the limbic cortex
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lingual gyrus (between mild and moderate) and middle occipital gyrus (between normal and mild)
- between mild and moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), postcentral gyrus medial segment (between mild and moderate) and precuneus (mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior orbital gyrus (between normal and mild) and anterior orbital gyrus (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. temporal gyrus (between normal and mild) and planum polare (between normal and mild) | CN |
NIFD_1_S_0238_MR_t1_mprage__br_raw_20160902144226204_127_S495765_I771932_dupl_3 | On a T1-weighted brain MRI of a 67-year-old male subject, we observed:
For the ventricles:
- no enlargement observed in the 4th ventricle
- external csf remains within normal size parameters, with no enlargement detected
- between normal and mild right enlargement of the lateral ventricle
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no enlargement observed in the 3rd ventricle
For the subcortical structures:
- accumbens presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the amygdala
- no degenerative or atrophic changes noted in the caudate
- no pathological changes consistent with atrophy detected in the ventral dc
- pallidum remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the putamen
- mild right atrophy of the hippocampus
- no observable atrophic alterations in the basal forebrain
- thalamus presents with a healthy appearance, free from atrophy
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (between normal and mild) and inf. occipital gyrus (between normal and mild)
- between normal and mild atrophy of the limbic cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild)
- no pathological changes consistent with atrophy detected in the temporal lobe
- parietal lobe appears structurally intact with no atrophic changes
- no signs of atrophy detected in the insular cortex
- frontal lobe remains normal, with no signs of tissue loss | CN |
NIFD_1_S_0209_MR_T1_mprage_S3_DIS3D_br_raw_20140901123615201_24_S229648_I442043_dupl_5 | On a T1-weighted brain MRI of a 58-year-old female subject, we observed:
For the ventricles:
- between moderate and severe enlargement of the 3rd ventricle
- between mild and moderate enlargement of the external csf
- between mild and moderate bilateral lateral ventricle enlargement
- no pathological changes consistent with enlargement noted in the 4th ventricle
- mild bilateral inf. lateral ventricle enlargement
For the cerebral cortex:
- between mild and moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate), middle cingulate gyrus (between normal and mild) and parahippocampal gyrus (between normal and mild)
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (between normal and mild), opercular inf. frontal gyrus (moderate), orbital inf. frontal gyrus (between normal and mild), triangular inf. frontal gyrus (moderate), medial frontal cortex (between mild and moderate), middle frontal gyrus (between mild and moderate), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus (moderate) and sup. frontal gyrus medial segment (between normal and mild)
- temporal lobe maintains its normal morphology without atrophic features
- the parietal lobe shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the occipital lobe
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (between normal and mild) and frontal operculum (mild)
For the subcortical structures:
- mild bilateral amygdala atrophy
- between mild and moderate bilateral accumbens atrophy
- between normal and mild right atrophy of the pallidum
- mild bilateral thalamus atrophy
- severe bilateral caudate atrophy
- ventral dc presents with a healthy appearance, free from atrophy
- basal forebrain appears structurally intact with no atrophic changes
- hippocampus maintains its normal morphology without atrophic features
- moderate bilateral putamen atrophy, more pronounced on the right | BV |
ADNI_024_S_4280_MR_MPRAGE_br_raw_20111018163207473_117_S125582_I261332_dupl_4 | On a T1-weighted brain MRI of a 80-year-old male subject, we observed:
For the ventricles:
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- moderate enlargement of the external csf
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no enlargement observed in the 4th ventricle
- 3rd ventricle is free from enlargement or excessive growth
For the cerebral cortex:
- mild atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: entorhinal area (mild) and parahippocampal gyrus (mild)
- the parietal lobe shows no structural abnormalities indicative of atrophy
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal pole (between normal and mild) and posterior orbital gyrus (moderate)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (between normal and mild), transverse temporal gyrus (between normal and mild) and temporal pole (between normal and mild)
- no degenerative or atrophic changes noted in the insular cortex
- no observable atrophic alterations in the occipital lobe
For the subcortical structures:
- no observable atrophic alterations in the ventral dc
- no observable atrophic alterations in the putamen
- no observable atrophic alterations in the basal forebrain
- pallidum maintains its normal morphology without atrophic features
- between normal and mild left atrophy of the thalamus
- severe bilateral amygdala atrophy, more pronounced on the right
- the caudate shows no structural abnormalities indicative of atrophy
- no pathological changes consistent with atrophy detected in the accumbens
- between moderate and severe bilateral hippocampus atrophy | AD |
ADNI_127_S_4198_MR_Accelerated_Sag_IR-SPGR__br_raw_20110902083648052_131_S121087_I254317_dupl_3 | On a T1-weighted brain MRI of a 78-year-old female subject, we observed:
For the cerebral cortex:
- the insular cortex shows no structural abnormalities indicative of atrophy
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus (mild) and supramarginal gyrus (between normal and mild)
- no evidence of atrophy or degeneration in the frontal lobe
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (mild), cuneus (between normal and mild) and inf. occipital gyrus (between normal and mild)
- no observable atrophic alterations in the temporal lobe
- no signs of atrophy detected in the limbic cortex
For the subcortical structures:
- no degenerative or atrophic changes noted in the ventral dc
- no pathological changes consistent with atrophy detected in the caudate
- no signs of atrophy detected in the thalamus
- between normal and mild bilateral accumbens atrophy
- amygdala presents with a healthy appearance, free from atrophy
- pallidum appears structurally intact with no atrophic changes
- no observable atrophic alterations in the basal forebrain
- no signs of atrophy detected in the putamen
- no evidence of atrophy or degeneration in the hippocampus
For the ventricles:
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- external csf appears structurally intact, with no evidence of enlargement
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- no pathological changes consistent with enlargement noted in the 4th ventricle
- no pathological changes consistent with enlargement noted in the lateral ventricle | CN |
ADNI_098_S_4003_MR_Accelerated_Sag_IR-SPGR__br_raw_20110322131336182_62_S102158_I224611_dupl_2 | On a T1-weighted brain MRI of a 72-year-old female subject, we observed:
For the ventricles:
- no abnormal enlargement observed in the inf. lateral ventricle
- lateral ventricle is free from enlargement or excessive growth
- 4th ventricle appears structurally intact, with no evidence of enlargement
- no signs of enlargement detected in the 3rd ventricle
- no abnormal enlargement observed in the external csf
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in triangular inf. frontal gyrus (between normal and mild) and medial frontal cortex (between normal and mild)
- parietal lobe presents with a healthy appearance, free from atrophy
- occipital lobe appears structurally intact with no atrophic changes
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (mild) and planum temporale (mild)
- insular cortex appears structurally intact with no atrophic changes
- limbic cortex maintains its normal morphology without atrophic features
For the subcortical structures:
- no degenerative or atrophic changes noted in the accumbens
- ventral dc remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the basal forebrain
- no pathological changes consistent with atrophy detected in the amygdala
- no observable atrophic alterations in the hippocampus
- no signs of atrophy detected in the putamen
- no observable atrophic alterations in the thalamus
- no degenerative or atrophic changes noted in the pallidum
- no pathological changes consistent with atrophy detected in the caudate | CN |
ADNI_127_S_5028_MR_Accelerated_Sag_IR-SPGR__br_raw_20121114162609124_113_S174622_I346691_dupl_5 | On a T1-weighted brain MRI of a 62-year-old male subject, we observed:
For the subcortical structures:
- between normal and mild right atrophy of the hippocampus
- between normal and mild bilateral caudate atrophy
- putamen maintains its normal morphology without atrophic features
- pallidum presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the ventral dc
- no evidence of atrophy or degeneration in the thalamus
- accumbens remains normal, with no signs of tissue loss
- between normal and mild atrophy of the amygdala
- basal forebrain appears structurally intact with no atrophic changes
For the cerebral cortex:
- no observable atrophic alterations in the parietal lobe
- no pathological changes consistent with atrophy detected in the insular cortex
- no observable atrophic alterations in the temporal lobe
- occipital lobe maintains its normal morphology without atrophic features
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (mild) and supplementary motor cortex (between normal and mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between mild and moderate) and posterior cingulate gyrus (between normal and mild)
For the ventricles:
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- no observable enlargement or abnormal growth in the 4th ventricle
- external csf is free from enlargement or excessive growth | AD |
ADNI_098_S_4201_MR_Accelerated_Sag_IR-SPGR__br_raw_20110915152919253_90_S122171_I256181_dupl_4 | On a T1-weighted brain MRI of a 64-year-old female subject, we observed:
For the cerebral cortex:
- the parietal lobe shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the occipital lobe
- limbic cortex remains normal, with no signs of tissue loss
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (between normal and mild) and sup. frontal gyrus medial segment (between normal and mild)
- no observable atrophic alterations in the insular cortex
- between moderate and severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (severe), sup. temporal gyrus (between moderate and severe) and temporal pole (between normal and mild)
For the subcortical structures:
- between normal and mild right atrophy of the caudate
- no evidence of atrophy or degeneration in the ventral dc
- mild atrophy of the accumbens, more pronounced on the right
- no signs of atrophy detected in the basal forebrain
- no observable atrophic alterations in the hippocampus
- pallidum presents with a healthy appearance, free from atrophy
- between mild and moderate bilateral amygdala atrophy, more pronounced on the right
- no degenerative or atrophic changes noted in the thalamus
- no pathological changes consistent with atrophy detected in the putamen
For the ventricles:
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- mild enlargement of the external csf
- lateral ventricle remains within normal size parameters, with no enlargement detected
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement | AD |
NIFD_1_S_0266_MR_t1_mprage__br_raw_20160902212027546_148_S496336_I772588_dupl_4 | On a T1-weighted brain MRI of a 68-year-old female subject, we observed:
For the subcortical structures:
- accumbens remains normal, with no signs of tissue loss
- ventral dc appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the basal forebrain
- between normal and mild atrophy of the hippocampus, more pronounced on the right
- amygdala remains normal, with no signs of tissue loss
- no signs of atrophy detected in the pallidum
- no signs of atrophy detected in the thalamus
- putamen presents with a healthy appearance, free from atrophy
- caudate presents with a healthy appearance, free from atrophy
For the cerebral cortex:
- limbic cortex presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the insular cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (between normal and mild) and sup. frontal gyrus (between normal and mild)
- no observable atrophic alterations in the temporal lobe
- between normal and mild atrophy of the occipital lobe, with focal volume loss observed in the following subregions: calcarine cortex (between normal and mild) and lingual gyrus (between normal and mild)
- parietal lobe remains normal, with no signs of tissue loss
For the ventricles:
- inf. lateral ventricle is free from enlargement or excessive growth
- no abnormal enlargement observed in the 3rd ventricle
- no pathological changes consistent with enlargement noted in the external csf
- between mild and moderate bilateral lateral ventricle enlargement, more pronounced on the right
- no observable enlargement or abnormal growth in the 4th ventricle | CN |
ADNI_153_S_4172_MR_MPRAGE_br_raw_20110817113413375_135_S119196_I251187_dupl_1 | On a T1-weighted brain MRI of a 76-year-old male subject, we observed:
For the ventricles:
- no abnormal enlargement observed in the external csf
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- 4th ventricle is free from enlargement or excessive growth
For the subcortical structures:
- mild bilateral accumbens atrophy, more pronounced on the left
- between normal and mild left atrophy of the pallidum
- moderate bilateral caudate atrophy, more pronounced on the left
- basal forebrain appears structurally intact with no atrophic changes
- between moderate and severe bilateral putamen atrophy, more pronounced on the left
- ventral dc appears structurally intact with no atrophic changes
- between normal and mild left atrophy of the amygdala
- no pathological changes consistent with atrophy detected in the thalamus
- between normal and mild left atrophy of the hippocampus
For the cerebral cortex:
- between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (between normal and mild), frontal operculum (between normal and mild) and parietal operculum (between mild and moderate)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal pole (between normal and mild) and middle frontal gyrus (mild)
- limbic cortex presents with a healthy appearance, free from atrophy
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (between normal and mild) and inf. temporal gyrus (between normal and mild)
- no observable atrophic alterations in the occipital lobe
- between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: postcentral gyrus (between normal and mild) and supramarginal gyrus (mild) | AD |
ADNI_021_S_4718_MR_Accelerated_Sag_IR-SPGR__br_raw_20120516162344538_10_S150673_I304759_dupl_5 | On a T1-weighted brain MRI of a 79-year-old male subject, we observed:
For the cerebral cortex:
- no observable atrophic alterations in the insular cortex
- severe bilateral parietal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: angular gyrus (moderate), postcentral gyrus (mild), precuneus (mild) and supramarginal gyrus (between normal and mild)
- the occipital lobe shows no structural abnormalities indicative of atrophy
- limbic cortex presents with a healthy appearance, free from atrophy
- frontal lobe remains normal, with no signs of tissue loss
- between moderate and severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (between mild and moderate), inf. temporal gyrus (between mild and moderate) and middle temporal gyrus (moderate)
For the subcortical structures:
- between normal and mild right atrophy of the caudate
- mild bilateral accumbens atrophy
- severe bilateral amygdala atrophy, more pronounced on the right
- mild right atrophy of the thalamus
- between normal and mild atrophy of the hippocampus, more pronounced on the right
- putamen presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the ventral dc
- no pathological changes consistent with atrophy detected in the pallidum
- no pathological changes consistent with atrophy detected in the basal forebrain
For the ventricles:
- no enlargement observed in the 3rd ventricle
- mild enlargement of the external csf
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
- 4th ventricle remains within normal size parameters, with no enlargement detected
- lateral ventricle maintains its normal volume without signs of enlargement | AD |
ADNI_016_S_5032_MR_Accelerated_SAG_IR-SPGR__br_raw_20121130134021740_63_S175940_I348593_dupl_4 | On a T1-weighted brain MRI of a 78-year-old female subject, we observed:
For the ventricles:
- inf. lateral ventricle is free from enlargement or excessive growth
- the external csf shows no structural abnormalities indicative of enlargement
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- no pathological changes consistent with enlargement noted in the 4th ventricle
For the subcortical structures:
- no evidence of atrophy or degeneration in the putamen
- between mild and moderate bilateral accumbens atrophy
- pallidum presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the thalamus
- no pathological changes consistent with atrophy detected in the basal forebrain
- caudate remains normal, with no signs of tissue loss
- between normal and mild right atrophy of the hippocampus
- moderate bilateral amygdala atrophy, more pronounced on the right
- ventral dc appears structurally intact with no atrophic changes
For the cerebral cortex:
- no evidence of atrophy or degeneration in the limbic cortex
- no signs of atrophy detected in the insular cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lateral orbital gyrus (between normal and mild) and medial frontal cortex (mild)
- occipital lobe remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the temporal lobe
- parietal lobe remains normal, with no signs of tissue loss | AD |
ADNI_036_S_4894_MR_MPRAGE_br_raw_20120810124944746_175_S160488_I323094_dupl_5 | On a T1-weighted brain MRI of a 61-year-old female subject, we observed:
For the subcortical structures:
- between mild and moderate atrophy of the amygdala, more pronounced on the left
- the pallidum shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the accumbens
- no signs of atrophy detected in the ventral dc
- no observable atrophic alterations in the basal forebrain
- between moderate and severe bilateral hippocampus atrophy, more pronounced on the left
- between mild and moderate bilateral caudate atrophy, more pronounced on the left
- no signs of atrophy detected in the thalamus
- between normal and mild bilateral putamen atrophy, more pronounced on the left
For the cerebral cortex:
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (between normal and mild)
- insular cortex appears structurally intact with no atrophic changes
- mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), precuneus (between normal and mild) and supramarginal gyrus (mild)
- occipital lobe maintains its normal morphology without atrophic features
- between mild and moderate atrophy of the temporal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: inf. temporal gyrus (mild), middle temporal gyrus (mild) and sup. temporal gyrus (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (mild) and sup. frontal gyrus (moderate)
For the ventricles:
- mild enlargement of the external csf
- no abnormal enlargement observed in the 4th ventricle
- no abnormal enlargement observed in the 3rd ventricle
- mild enlargement of the inf. lateral ventricle, more pronounced on the left
- no enlargement observed in the lateral ventricle | AD |
ADNI_098_S_4201_MR_Accelerated_Sag_IR-SPGR__br_raw_20110915152919253_90_S122171_I256181_dupl_3 | On a T1-weighted brain MRI of a 64-year-old female subject, we observed:
For the cerebral cortex:
- no evidence of atrophy or degeneration in the occipital lobe
- between moderate and severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: middle temporal gyrus (severe), sup. temporal gyrus (between moderate and severe) and temporal pole (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (between normal and mild) and sup. frontal gyrus medial segment (between normal and mild)
- insular cortex maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the limbic cortex
- no degenerative or atrophic changes noted in the parietal lobe
For the subcortical structures:
- putamen appears structurally intact with no atrophic changes
- mild atrophy of the accumbens, more pronounced on the right
- between mild and moderate bilateral amygdala atrophy, more pronounced on the right
- no evidence of atrophy or degeneration in the ventral dc
- between normal and mild right atrophy of the caudate
- no pathological changes consistent with atrophy detected in the hippocampus
- no pathological changes consistent with atrophy detected in the pallidum
- no observable atrophic alterations in the thalamus
- basal forebrain presents with a healthy appearance, free from atrophy
For the ventricles:
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- no pathological changes consistent with enlargement noted in the lateral ventricle
- 3rd ventricle maintains its normal volume without signs of enlargement
- 4th ventricle appears structurally intact, with no evidence of enlargement
- mild enlargement of the external csf | AD |
NIFD_1_S_0091_MR_T1_mprage_S3_DIS3D_br_raw_20170817104021048_43_S597455_I890811_dupl_5 | On a T1-weighted brain MRI of a 57-year-old male subject, we observed:
For the subcortical structures:
- hippocampus maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the caudate
- moderate bilateral thalamus atrophy
- basal forebrain maintains its normal morphology without atrophic features
- putamen maintains its normal morphology without atrophic features
- no observable atrophic alterations in the pallidum
- the amygdala shows no structural abnormalities indicative of atrophy
- between normal and mild left atrophy of the accumbens
- no degenerative or atrophic changes noted in the ventral dc
For the ventricles:
- no abnormal enlargement observed in the external csf
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- no enlargement observed in the inf. lateral ventricle
- between normal and mild enlargement of the 3rd ventricle
- between normal and mild right enlargement of the lateral ventricle
For the cerebral cortex:
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (between normal and mild), sup. temporal gyrus (between normal and mild) and transverse temporal gyrus (between normal and mild)
- between moderate and severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: posterior insula (moderate), central operculum (between normal and mild) and parietal operculum (between mild and moderate)
- occipital lobe remains normal, with no signs of tissue loss
- no signs of atrophy detected in the parietal lobe
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: entorhinal area (between normal and mild) and posterior cingulate gyrus (mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior orbital gyrus (mild) and posterior orbital gyrus (mild) | BV |
ADNI_099_S_4104_MR_MPRAGE_br_raw_20110701121555888_20_S113393_I243001_dupl_4 | On a T1-weighted brain MRI of a 73-year-old male subject, we observed:
For the cerebral cortex:
- no evidence of atrophy or degeneration in the limbic cortex
- occipital lobe presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the insular cortex
- parietal lobe presents with a healthy appearance, free from atrophy
- the temporal lobe shows no structural abnormalities indicative of atrophy
- frontal lobe presents with a healthy appearance, free from atrophy
For the subcortical structures:
- basal forebrain remains normal, with no signs of tissue loss
- hippocampus appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the caudate
- no evidence of atrophy or degeneration in the amygdala
- the accumbens shows no structural abnormalities indicative of atrophy
- putamen maintains its normal morphology without atrophic features
- ventral dc appears structurally intact with no atrophic changes
- thalamus appears structurally intact with no atrophic changes
- pallidum presents with a healthy appearance, free from atrophy
For the ventricles:
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- between normal and mild enlargement of the external csf
- mild enlargement of the 4th ventricle
- lateral ventricle remains within normal size parameters, with no enlargement detected
- no enlargement observed in the inf. lateral ventricle | CN |
NIFD_1_S_0040_MR_t1_mprage_S3_DIS3D_br_raw_20150522131343256_7_S261234_I494492_dupl_4 | On a T1-weighted brain MRI of a 71-year-old female subject, we observed:
For the cerebral cortex:
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (between normal and mild), middle temporal gyrus (between normal and mild) and sup. temporal gyrus (mild)
- no degenerative or atrophic changes noted in the occipital lobe
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between normal and mild), frontal operculum (between mild and moderate) and parietal operculum (between mild and moderate)
- between normal and mild atrophy of the parietal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: precuneus (between normal and mild) and angular gyrus (between normal and mild)
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (severe), opercular inf. frontal gyrus (between mild and moderate), triangular inf. frontal gyrus (severe), medial frontal cortex (moderate), middle frontal gyrus (severe), lateral orbital gyrus (mild), medial orbital gyrus (between mild and moderate), posterior orbital gyrus (moderate), sup. frontal gyrus (moderate), sup. frontal gyrus medial segment (mild) and precentral gyrus (between normal and mild)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe), middle cingulate gyrus (between mild and moderate), posterior cingulate gyrus (between normal and mild) and parahippocampal gyrus (between normal and mild)
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- mild enlargement of the 3rd ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
- moderate bilateral lateral ventricle enlargement
- severe enlargement of the external csf
For the subcortical structures:
- basal forebrain remains normal, with no signs of tissue loss
- between moderate and severe bilateral pallidum atrophy, more pronounced on the left
- between moderate and severe bilateral putamen atrophy, more pronounced on the left
- mild atrophy of the hippocampus, more pronounced on the left
- mild bilateral ventral dc atrophy
- severe bilateral thalamus atrophy, more pronounced on the left
- severe bilateral accumbens atrophy, more pronounced on the left
- severe bilateral caudate atrophy, more pronounced on the left
- moderate bilateral amygdala atrophy | BV |
NIFD_1_S_0053_MR_T1_mprage_S3_DIS3D_br_raw_20170817095339381_67_S597254_I890544_dupl_2 | On a T1-weighted brain MRI of a 69-year-old male subject, we observed:
For the subcortical structures:
- no signs of atrophy detected in the basal forebrain
- severe bilateral amygdala atrophy
- no pathological changes consistent with atrophy detected in the ventral dc
- between moderate and severe bilateral hippocampus atrophy
- severe bilateral accumbens atrophy, more pronounced on the right
- no observable atrophic alterations in the pallidum
- the caudate shows no structural abnormalities indicative of atrophy
- between mild and moderate bilateral putamen atrophy, more pronounced on the left
- thalamus maintains its normal morphology without atrophic features
For the ventricles:
- mild enlargement of the external csf
- 4th ventricle remains within normal size parameters, with no enlargement detected
- severe bilateral inf. lateral ventricle enlargement
- between normal and mild enlargement of the lateral ventricle, more pronounced on the left
- no signs of enlargement detected in the 3rd ventricle
For the cerebral cortex:
- no evidence of atrophy or degeneration in the frontal lobe
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (moderate), anterior cingulate gyrus (severe) and parahippocampal gyrus (between normal and mild)
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (moderate) and parietal operculum (between mild and moderate)
- no degenerative or atrophic changes noted in the parietal lobe
- severe bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (severe), planum temporale (mild), inf. temporal gyrus (severe), sup. temporal gyrus (between normal and mild) and temporal pole (severe)
- occipital lobe remains normal, with no signs of tissue loss | SV |
NIFD_1_S_0040_MR_t1_mprage_S3_DIS3D_br_raw_20150522131343256_7_S261234_I494492_dupl_3 | On a T1-weighted brain MRI of a 71-year-old female subject, we observed:
For the ventricles:
- mild enlargement of the 3rd ventricle
- no abnormal enlargement observed in the 4th ventricle
- moderate bilateral lateral ventricle enlargement
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left
- severe enlargement of the external csf
For the subcortical structures:
- severe bilateral caudate atrophy, more pronounced on the left
- no degenerative or atrophic changes noted in the basal forebrain
- severe bilateral accumbens atrophy, more pronounced on the left
- between moderate and severe bilateral putamen atrophy, more pronounced on the left
- mild bilateral ventral dc atrophy
- between moderate and severe bilateral pallidum atrophy, more pronounced on the left
- severe bilateral thalamus atrophy, more pronounced on the left
- moderate bilateral amygdala atrophy
- mild atrophy of the hippocampus, more pronounced on the left
For the cerebral cortex:
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe), middle cingulate gyrus (between mild and moderate), posterior cingulate gyrus (between normal and mild) and parahippocampal gyrus (between normal and mild)
- between normal and mild atrophy of the parietal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: precuneus (between normal and mild) and angular gyrus (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (between normal and mild), middle temporal gyrus (between normal and mild) and sup. temporal gyrus (mild)
- severe bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between normal and mild), frontal operculum (between mild and moderate) and parietal operculum (between mild and moderate)
- no degenerative or atrophic changes noted in the occipital lobe
- severe bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (severe), opercular inf. frontal gyrus (between mild and moderate), triangular inf. frontal gyrus (severe), medial frontal cortex (moderate), middle frontal gyrus (severe), lateral orbital gyrus (mild), medial orbital gyrus (between mild and moderate), posterior orbital gyrus (moderate), sup. frontal gyrus (moderate), sup. frontal gyrus medial segment (mild) and precentral gyrus (between normal and mild) | BV |
ADNI_011_S_4827_MR_MPRAGE_br_raw_20120703085506250_153_S156389_I314042_dupl_3 | On a T1-weighted brain MRI of a 72-year-old male subject, we observed:
For the subcortical structures:
- no degenerative or atrophic changes noted in the caudate
- the ventral dc shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the pallidum
- mild left atrophy of the hippocampus
- the basal forebrain shows no structural abnormalities indicative of atrophy
- between normal and mild atrophy of the putamen, more pronounced on the left
- moderate bilateral amygdala atrophy, more pronounced on the left
- accumbens maintains its normal morphology without atrophic features
- mild left atrophy of the thalamus
For the cerebral cortex:
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in central operculum (between normal and mild) and frontal operculum (between normal and mild)
- between normal and mild atrophy of the parietal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: postcentral gyrus (between normal and mild) and postcentral gyrus medial segment (between mild and moderate)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between normal and mild) and inf. occipital gyrus (between normal and mild)
- mild bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild) and middle frontal gyrus (between normal and mild)
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: sup. temporal gyrus (between normal and mild)
For the ventricles:
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- severe enlargement of the external csf
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- 3rd ventricle is free from enlargement or excessive growth | AD |
ADNI_024_S_4158_MR_MPRAGE_br_raw_20110815114120024_16_S118583_I250350_dupl_1 | On a T1-weighted brain MRI of a 85-year-old male subject, we observed:
For the ventricles:
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- no enlargement observed in the 4th ventricle
- external csf remains within normal size parameters, with no enlargement detected
- inf. lateral ventricle is free from enlargement or excessive growth
- no pathological changes consistent with enlargement noted in the lateral ventricle
For the subcortical structures:
- between normal and mild atrophy of the accumbens
- hippocampus appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the thalamus
- putamen appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the amygdala
- the basal forebrain shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the caudate
- pallidum appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the ventral dc
For the cerebral cortex:
- occipital lobe presents with a healthy appearance, free from atrophy
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in orbital inf. frontal gyrus (between normal and mild) and sup. frontal gyrus medial segment (between normal and mild)
- no observable atrophic alterations in the temporal lobe
- no signs of atrophy detected in the limbic cortex
- no signs of atrophy detected in the insular cortex
- no pathological changes consistent with atrophy detected in the parietal lobe | CN |
ADNI_131_S_5138_MR_MPRAGE_br_raw_20130417113829938_29_S187196_I367565_dupl_5 | On a T1-weighted brain MRI of a 61-year-old male subject, we observed:
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the accumbens
- amygdala appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the putamen
- no observable atrophic alterations in the caudate
- basal forebrain appears structurally intact with no atrophic changes
- ventral dc remains normal, with no signs of tissue loss
- thalamus appears structurally intact with no atrophic changes
- hippocampus appears structurally intact with no atrophic changes
- the pallidum shows no structural abnormalities indicative of atrophy
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the frontal lobe
- occipital lobe remains normal, with no signs of tissue loss
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. parietal lobule (mild) and supramarginal gyrus (between normal and mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior insula (between normal and mild) and central operculum (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. temporal gyrus (mild) and transverse temporal gyrus (mild)
- the limbic cortex shows no structural abnormalities indicative of atrophy
For the ventricles:
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- lateral ventricle remains within normal size parameters, with no enlargement detected
- no signs of enlargement detected in the external csf
- the 4th ventricle shows no structural abnormalities indicative of enlargement | AD |
NIFD_1_S_0096_MR_T1_mprage_S3_DIS3D_br_raw_20170817133934845_74_S598211_I891811_dupl_4 | On a T1-weighted brain MRI of a 69-year-old male subject, we observed:
For the subcortical structures:
- between normal and mild right atrophy of the ventral dc
- no signs of atrophy detected in the hippocampus
- mild atrophy of the thalamus, more pronounced on the right
- no degenerative or atrophic changes noted in the amygdala
- putamen presents with a healthy appearance, free from atrophy
- no degenerative or atrophic changes noted in the pallidum
- caudate presents with a healthy appearance, free from atrophy
- accumbens remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the basal forebrain
For the ventricles:
- no abnormal enlargement observed in the inf. lateral ventricle
- between normal and mild enlargement of the 3rd ventricle
- no enlargement observed in the 4th ventricle
- no abnormal enlargement observed in the lateral ventricle
- between normal and mild enlargement of the external csf
For the cerebral cortex:
- the occipital lobe shows no structural abnormalities indicative of atrophy
- limbic cortex maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the temporal lobe
- between normal and mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: frontal operculum (mild)
- no pathological changes consistent with atrophy detected in the parietal lobe
- frontal lobe appears structurally intact with no atrophic changes | BV |
NIFD_1_S_0176_MR_T1_mprage_S3_DIS3D_br_raw_20140831170526452_55_S228978_I441286_dupl_4 | On a T1-weighted brain MRI of a 53-year-old male subject, we observed:
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (between normal and mild) and subcallosal area (mild)
- the insular cortex shows no structural abnormalities indicative of atrophy
- parietal lobe remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the occipital lobe
- temporal lobe remains normal, with no signs of tissue loss
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (mild) and middle cingulate gyrus (between normal and mild)
For the subcortical structures:
- no degenerative or atrophic changes noted in the hippocampus
- no evidence of atrophy or degeneration in the basal forebrain
- no evidence of atrophy or degeneration in the amygdala
- between normal and mild bilateral thalamus atrophy
- no signs of atrophy detected in the accumbens
- putamen appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the caudate
- between normal and mild bilateral ventral dc atrophy
- no degenerative or atrophic changes noted in the pallidum
For the ventricles:
- external csf appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the lateral ventricle
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- 4th ventricle is free from enlargement or excessive growth
- 3rd ventricle maintains its normal volume without signs of enlargement | CN |
ADNI_011_S_4827_MR_MPRAGE_br_raw_20120703085506250_153_S156389_I314042_dupl_4 | On a T1-weighted brain MRI of a 72-year-old male subject, we observed:
For the ventricles:
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no abnormal enlargement observed in the 3rd ventricle
- no abnormal enlargement observed in the 4th ventricle
- lateral ventricle remains within normal size parameters, with no enlargement detected
- severe enlargement of the external csf
For the subcortical structures:
- between normal and mild atrophy of the putamen, more pronounced on the left
- no observable atrophic alterations in the pallidum
- moderate bilateral amygdala atrophy, more pronounced on the left
- no signs of atrophy detected in the accumbens
- no signs of atrophy detected in the caudate
- ventral dc maintains its normal morphology without atrophic features
- mild left atrophy of the hippocampus
- mild left atrophy of the thalamus
- no degenerative or atrophic changes noted in the basal forebrain
For the cerebral cortex:
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in central operculum (between normal and mild) and frontal operculum (between normal and mild)
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: sup. temporal gyrus (between normal and mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild)
- mild bilateral frontal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild) and middle frontal gyrus (between normal and mild)
- between normal and mild atrophy of the parietal lobe, more pronounced on the left, with focal volume loss observed in the following subregions: postcentral gyrus (between normal and mild) and postcentral gyrus medial segment (between mild and moderate)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between normal and mild) and inf. occipital gyrus (between normal and mild) | AD |
ADNI_130_S_5059_MR_MPRAGE_br_raw_20130212105012862_33_S182011_I358776_dupl_4 | On a T1-weighted brain MRI of a 73-year-old male subject, we observed:
For the subcortical structures:
- thalamus remains normal, with no signs of tissue loss
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- no evidence of atrophy or degeneration in the pallidum
- no observable atrophic alterations in the caudate
- no signs of atrophy detected in the ventral dc
- putamen appears structurally intact with no atrophic changes
- basal forebrain remains normal, with no signs of tissue loss
- between normal and mild bilateral amygdala atrophy
- the accumbens shows no structural abnormalities indicative of atrophy
For the ventricles:
- 4th ventricle appears structurally intact, with no evidence of enlargement
- lateral ventricle is free from enlargement or excessive growth
- between moderate and severe bilateral inf. lateral ventricle enlargement
- external csf remains within normal size parameters, with no enlargement detected
- between normal and mild enlargement of the 3rd ventricle
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the insular cortex
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle occipital gyrus (mild) and occipital fusiform gyrus (between normal and mild)
- no signs of atrophy detected in the limbic cortex
- parietal lobe remains normal, with no signs of tissue loss
- no signs of atrophy detected in the frontal lobe
- between mild and moderate bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: planum temporale (between normal and mild), inf. temporal gyrus (between normal and mild), middle temporal gyrus (mild) and sup. temporal gyrus (between normal and mild) | AD |
NIFD_1_S_0238_MR_t1_mprage__br_raw_20160902144226204_127_S495765_I771932_dupl_4 | On a T1-weighted brain MRI of a 67-year-old male subject, we observed:
For the cerebral cortex:
- parietal lobe presents with a healthy appearance, free from atrophy
- between normal and mild atrophy of the limbic cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild)
- frontal lobe appears structurally intact with no atrophic changes
- temporal lobe presents with a healthy appearance, free from atrophy
- insular cortex presents with a healthy appearance, free from atrophy
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (between normal and mild) and inf. occipital gyrus (between normal and mild)
For the ventricles:
- no enlargement observed in the 3rd ventricle
- the external csf shows no structural abnormalities indicative of enlargement
- no enlargement observed in the inf. lateral ventricle
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- between normal and mild right enlargement of the lateral ventricle
For the subcortical structures:
- pallidum maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the ventral dc
- no degenerative or atrophic changes noted in the amygdala
- no observable atrophic alterations in the basal forebrain
- no evidence of atrophy or degeneration in the accumbens
- caudate maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the thalamus
- mild right atrophy of the hippocampus
- putamen appears structurally intact with no atrophic changes | CN |
ADNI_024_S_4084_MR_MPRAGE_br_raw_20110620162005802_83_S112129_I241013_dupl_1 | On a T1-weighted brain MRI of a 69-year-old female subject, we observed:
For the subcortical structures:
- between mild and moderate bilateral putamen atrophy
- no degenerative or atrophic changes noted in the accumbens
- between normal and mild left atrophy of the caudate
- no signs of atrophy detected in the amygdala
- pallidum appears structurally intact with no atrophic changes
- no observable atrophic alterations in the basal forebrain
- the thalamus shows no structural abnormalities indicative of atrophy
- ventral dc appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the hippocampus
For the cerebral cortex:
- the limbic cortex shows no structural abnormalities indicative of atrophy
- insular cortex presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the frontal lobe
- no signs of atrophy detected in the parietal lobe
- no degenerative or atrophic changes noted in the temporal lobe
- between normal and mild atrophy of the occipital lobe, with focal volume loss observed in the following subregions: sup. occipital gyrus (mild) and inf. occipital gyrus (between normal and mild)
For the ventricles:
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- no enlargement observed in the lateral ventricle
- no abnormal enlargement observed in the external csf
- 4th ventricle is free from enlargement or excessive growth
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement | CN |
NIFD_1_S_0131_MR_T1_mprage_S3_DIS3D_br_raw_20130723102305083_133_S196174_I382122_dupl_2 | On a T1-weighted brain MRI of a 70-year-old female subject, we observed:
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (between mild and moderate) and posterior orbital gyrus (moderate)
- no evidence of atrophy or degeneration in the temporal lobe
- no pathological changes consistent with atrophy detected in the insular cortex
- occipital lobe presents with a healthy appearance, free from atrophy
- limbic cortex maintains its normal morphology without atrophic features
- no signs of atrophy detected in the parietal lobe
For the subcortical structures:
- no signs of atrophy detected in the putamen
- no observable atrophic alterations in the accumbens
- the ventral dc shows no structural abnormalities indicative of atrophy
- the hippocampus shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the caudate
- amygdala appears structurally intact with no atrophic changes
- thalamus remains normal, with no signs of tissue loss
- the pallidum shows no structural abnormalities indicative of atrophy
- basal forebrain remains normal, with no signs of tissue loss
For the ventricles:
- no observable enlargement or abnormal growth in the 4th ventricle
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- external csf remains within normal size parameters, with no enlargement detected
- no enlargement observed in the inf. lateral ventricle
- no abnormal enlargement observed in the lateral ventricle | CN |
ADNI_073_S_4739_MR_MPRAGE_br_raw_20120516150253805_135_S150755_I304867_dupl_3 | On a T1-weighted brain MRI of a 66-year-old male subject, we observed:
For the subcortical structures:
- basal forebrain maintains its normal morphology without atrophic features
- between normal and mild bilateral ventral dc atrophy
- no evidence of atrophy or degeneration in the amygdala
- no observable atrophic alterations in the putamen
- between normal and mild atrophy of the accumbens, more pronounced on the right
- the hippocampus shows no structural abnormalities indicative of atrophy
- between normal and mild bilateral caudate atrophy
- no pathological changes consistent with atrophy detected in the pallidum
- between normal and mild atrophy of the thalamus, more pronounced on the left
For the cerebral cortex:
- no evidence of atrophy or degeneration in the limbic cortex
- between mild and moderate bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild), middle temporal gyrus (between mild and moderate) and temporal pole (mild)
- insular cortex presents with a healthy appearance, free from atrophy
- mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between mild and moderate)
- mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: cuneus (mild) and occipital fusiform gyrus (between normal and mild)
- between normal and mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: precentral gyrus (mild) and sup. frontal gyrus medial segment (between normal and mild)
For the ventricles:
- no enlargement observed in the 3rd ventricle
- no abnormal enlargement observed in the 4th ventricle
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- no enlargement observed in the inf. lateral ventricle
- moderate enlargement of the external csf | CN |
ADNI_130_S_5059_MR_MPRAGE_br_raw_20130212105012862_33_S182011_I358776_dupl_2 | On a T1-weighted brain MRI of a 73-year-old male subject, we observed:
For the subcortical structures:
- caudate maintains its normal morphology without atrophic features
- pallidum maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the basal forebrain
- thalamus maintains its normal morphology without atrophic features
- no observable atrophic alterations in the ventral dc
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- putamen presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the accumbens
- between normal and mild bilateral amygdala atrophy
For the cerebral cortex:
- between mild and moderate bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: planum temporale (between normal and mild), inf. temporal gyrus (between normal and mild), middle temporal gyrus (mild) and sup. temporal gyrus (between normal and mild)
- limbic cortex remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the frontal lobe
- no signs of atrophy detected in the parietal lobe
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle occipital gyrus (mild) and occipital fusiform gyrus (between normal and mild)
- the insular cortex shows no structural abnormalities indicative of atrophy
For the ventricles:
- between normal and mild enlargement of the 3rd ventricle
- no observable enlargement or abnormal growth in the external csf
- no enlargement observed in the lateral ventricle
- no abnormal enlargement observed in the 4th ventricle
- between moderate and severe bilateral inf. lateral ventricle enlargement | AD |
NIFD_2_S_0014_MR_MT1__GradWarp__N3m_Br_20111229191004875_S134530_I274739_dupl_2 | On a T1-weighted brain MRI of a 53-year-old male subject, we observed:
For the ventricles:
- severe enlargement of the external csf
- severe bilateral lateral ventricle enlargement
- severe bilateral inf. lateral ventricle enlargement
- mild enlargement of the 3rd ventricle
- between mild and moderate enlargement of the 4th ventricle
For the subcortical structures:
- between normal and mild atrophy of the thalamus
- basal forebrain presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the ventral dc
- severe bilateral accumbens atrophy, more pronounced on the left
- severe bilateral caudate atrophy
- between normal and mild right atrophy of the hippocampus
- between moderate and severe bilateral putamen atrophy
- between mild and moderate bilateral amygdala atrophy
- moderate bilateral pallidum atrophy
For the cerebral cortex:
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate), central operculum (moderate) and parietal operculum (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (mild) and middle occipital gyrus (mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between mild and moderate)
- mild atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: sup. temporal gyrus (mild) and temporal pole (mild)
- between moderate and severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (mild), opercular inf. frontal gyrus (between normal and mild), middle frontal gyrus (mild), lateral orbital gyrus (between normal and mild), posterior orbital gyrus (between moderate and severe), sup. frontal gyrus (mild) and medial frontal cortex (between normal and mild)
- between moderate and severe bilateral parietal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), precuneus (between normal and mild), sup. parietal lobule (moderate) and supramarginal gyrus (between mild and moderate) | BV |
NIFD_1_S_0212_MR_T1_mprage_S3_DIS3D_br_raw_20170817105545257_129_S597537_I890918_dupl_5 | On a T1-weighted brain MRI of a 53-year-old female subject, we observed:
For the subcortical structures:
- no signs of atrophy detected in the hippocampus
- mild bilateral pallidum atrophy
- no pathological changes consistent with atrophy detected in the amygdala
- no observable atrophic alterations in the thalamus
- putamen appears structurally intact with no atrophic changes
- no signs of atrophy detected in the basal forebrain
- no degenerative or atrophic changes noted in the accumbens
- between normal and mild right atrophy of the ventral dc
- no pathological changes consistent with atrophy detected in the caudate
For the ventricles:
- external csf appears structurally intact, with no evidence of enlargement
- mild enlargement of the 3rd ventricle
- mild enlargement of the 4th ventricle
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- lateral ventricle maintains its normal volume without signs of enlargement
For the cerebral cortex:
- parietal lobe appears structurally intact with no atrophic changes
- the occipital lobe shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the limbic cortex
- the temporal lobe shows no structural abnormalities indicative of atrophy
- insular cortex maintains its normal morphology without atrophic features
- no signs of atrophy detected in the frontal lobe | CN |
ADNI_006_S_4485_MR_MPRAGE_br_raw_20120201124039752_139_S139148_I281882_dupl_5 | On a T1-weighted brain MRI of a 74-year-old male subject, we observed:
For the subcortical structures:
- no signs of atrophy detected in the hippocampus
- the caudate shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the putamen
- ventral dc maintains its normal morphology without atrophic features
- no observable atrophic alterations in the amygdala
- thalamus remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the accumbens
- between normal and mild left atrophy of the pallidum
- basal forebrain remains normal, with no signs of tissue loss
For the ventricles:
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- lateral ventricle remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the external csf
- moderate enlargement of the 4th ventricle
- no signs of enlargement detected in the inf. lateral ventricle
For the cerebral cortex:
- no degenerative or atrophic changes noted in the temporal lobe
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (mild) and postcentral gyrus (between normal and mild)
- no pathological changes consistent with atrophy detected in the frontal lobe
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lingual gyrus (between normal and mild) and inf. occipital gyrus (between normal and mild)
- limbic cortex presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the insular cortex | CN |
NIFD_1_S_0339_MR_T1_mprage_S3_DIS3D_br_raw_20170629002457144_144_S577807_I867541_dupl_3 | On a T1-weighted brain MRI of a 63-year-old female subject, we observed:
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- lateral ventricle maintains its normal volume without signs of enlargement
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- mild enlargement of the external csf
- no signs of enlargement detected in the 4th ventricle
For the cerebral cortex:
- no degenerative or atrophic changes noted in the parietal lobe
- the occipital lobe shows no structural abnormalities indicative of atrophy
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (mild), medial orbital gyrus (between mild and moderate) and medial frontal cortex (mild)
- moderate bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate), central operculum (mild) and parietal operculum (between normal and mild)
- severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (moderate), planum polare (between normal and mild), planum temporale (between normal and mild), inf. temporal gyrus (between moderate and severe), sup. temporal gyrus (between mild and moderate), temporal pole (severe) and middle temporal gyrus (mild)
- moderate bilateral limbic cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: entorhinal area (mild), anterior cingulate gyrus (moderate) and parahippocampal gyrus (between normal and mild)
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the thalamus
- between normal and mild right atrophy of the caudate
- between normal and mild atrophy of the putamen, more pronounced on the right
- no evidence of atrophy or degeneration in the pallidum
- severe bilateral accumbens atrophy, more pronounced on the right
- severe bilateral hippocampus atrophy, more pronounced on the right
- no pathological changes consistent with atrophy detected in the ventral dc
- severe bilateral amygdala atrophy, more pronounced on the right
- no evidence of atrophy or degeneration in the basal forebrain | SV |
NIFD_1_S_0024_MR_t1_mprage_S7_DIS3D_br_raw_20110203091851798_6_S98780_I215642_dupl_5 | On a T1-weighted brain MRI of a 67-year-old female subject, we observed:
For the cerebral cortex:
- no signs of atrophy detected in the occipital lobe
- the temporal lobe shows no structural abnormalities indicative of atrophy
- parietal lobe maintains its normal morphology without atrophic features
- the insular cortex shows no structural abnormalities indicative of atrophy
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (between normal and mild), middle frontal gyrus (mild), anterior orbital gyrus (between mild and moderate), lateral orbital gyrus (between normal and mild) and precentral gyrus medial segment (between normal and mild)
- no observable atrophic alterations in the limbic cortex
For the ventricles:
- between normal and mild enlargement of the external csf
- no observable enlargement or abnormal growth in the 3rd ventricle
- lateral ventricle is free from enlargement or excessive growth
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- between normal and mild left enlargement of the inf. lateral ventricle
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the basal forebrain
- no pathological changes consistent with atrophy detected in the hippocampus
- between normal and mild left atrophy of the amygdala
- no evidence of atrophy or degeneration in the thalamus
- caudate remains normal, with no signs of tissue loss
- between normal and mild atrophy of the accumbens
- no pathological changes consistent with atrophy detected in the ventral dc
- the putamen shows no structural abnormalities indicative of atrophy
- the pallidum shows no structural abnormalities indicative of atrophy | CN |
ADNI_135_S_5275_MR_MPRAGE_br_raw_20130805125009417_8_S197268_I384344_dupl_5 | On a T1-weighted brain MRI of a 78-year-old female subject, we observed:
For the cerebral cortex:
- no evidence of atrophy or degeneration in the limbic cortex
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (between mild and moderate) and occipital fusiform gyrus (mild)
- no pathological changes consistent with atrophy detected in the insular cortex
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (between mild and moderate) and sup. temporal gyrus (mild)
- parietal lobe remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the frontal lobe
For the subcortical structures:
- accumbens remains normal, with no signs of tissue loss
- no observable atrophic alterations in the basal forebrain
- between mild and moderate bilateral ventral dc atrophy
- between mild and moderate bilateral pallidum atrophy
- moderate bilateral putamen atrophy, more pronounced on the left
- no degenerative or atrophic changes noted in the amygdala
- between normal and mild right atrophy of the thalamus
- between normal and mild atrophy of the hippocampus, more pronounced on the right
- mild bilateral caudate atrophy, more pronounced on the left
For the ventricles:
- no enlargement observed in the external csf
- no abnormal enlargement observed in the 3rd ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
- no signs of enlargement detected in the inf. lateral ventricle
- between normal and mild bilateral lateral ventricle enlargement | AD |
NIFD_1_S_0279_MR_t1_mprage__br_raw_20160903204551965_44_S496713_I773020_dupl_1 | On a T1-weighted brain MRI of a 62-year-old female subject, we observed:
For the subcortical structures:
- the caudate shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the putamen
- no evidence of atrophy or degeneration in the basal forebrain
- the accumbens shows no structural abnormalities indicative of atrophy
- thalamus presents with a healthy appearance, free from atrophy
- ventral dc maintains its normal morphology without atrophic features
- hippocampus remains normal, with no signs of tissue loss
- pallidum appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the amygdala
For the ventricles:
- no observable enlargement or abnormal growth in the lateral ventricle
- no enlargement observed in the 4th ventricle
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- external csf maintains its normal volume without signs of enlargement
- no pathological changes consistent with enlargement noted in the 3rd ventricle
For the cerebral cortex:
- the limbic cortex shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the occipital lobe
- frontal lobe remains normal, with no signs of tissue loss
- no degenerative or atrophic changes noted in the temporal lobe
- no signs of atrophy detected in the parietal lobe
- no evidence of atrophy or degeneration in the insular cortex | CN |
ADNI_072_S_4103_MR_MPRAGE_br_raw_20110721105250665_38_S115543_I245969_dupl_5 | On a T1-weighted brain MRI of a 72-year-old male subject, we observed:
For the ventricles:
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- no enlargement observed in the inf. lateral ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
- external csf remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the 4th ventricle
For the subcortical structures:
- basal forebrain presents with a healthy appearance, free from atrophy
- putamen maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the thalamus
- ventral dc maintains its normal morphology without atrophic features
- hippocampus appears structurally intact with no atrophic changes
- caudate maintains its normal morphology without atrophic features
- the amygdala shows no structural abnormalities indicative of atrophy
- mild bilateral accumbens atrophy, more pronounced on the right
- no evidence of atrophy or degeneration in the pallidum
For the cerebral cortex:
- frontal lobe appears structurally intact with no atrophic changes
- the parietal lobe shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the limbic cortex
- no pathological changes consistent with atrophy detected in the insular cortex
- no pathological changes consistent with atrophy detected in the temporal lobe
- the occipital lobe shows no structural abnormalities indicative of atrophy | CN |
ADNI_011_S_4906_MR_MPRAGE_br_raw_20120904143307512_81_S165942_I330056_dupl_1 | On a T1-weighted brain MRI of a 76-year-old female subject, we observed:
For the subcortical structures:
- between normal and mild atrophy of the amygdala
- no signs of atrophy detected in the putamen
- pallidum presents with a healthy appearance, free from atrophy
- accumbens presents with a healthy appearance, free from atrophy
- mild atrophy of the hippocampus, more pronounced on the left
- basal forebrain appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the thalamus
- no observable atrophic alterations in the caudate
- between normal and mild bilateral ventral dc atrophy
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the limbic cortex
- no pathological changes consistent with atrophy detected in the frontal lobe
- between normal and mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: sup. temporal gyrus (between mild and moderate)
- the insular cortex shows no structural abnormalities indicative of atrophy
- parietal lobe presents with a healthy appearance, free from atrophy
- occipital lobe appears structurally intact with no atrophic changes
For the ventricles:
- no observable enlargement or abnormal growth in the external csf
- between normal and mild enlargement of the inf. lateral ventricle, more pronounced on the left
- between normal and mild enlargement of the lateral ventricle, more pronounced on the left
- 4th ventricle appears structurally intact, with no evidence of enlargement
- 3rd ventricle maintains its normal volume without signs of enlargement | AD |
NIFD_1_S_0237_MR_t1_mprage__br_raw_20160902142657075_120_S495712_I771873_dupl_3 | On a T1-weighted brain MRI of a 68-year-old female subject, we observed:
For the ventricles:
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- no signs of enlargement detected in the external csf
- 4th ventricle appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the lateral ventricle
For the cerebral cortex:
- no evidence of atrophy or degeneration in the limbic cortex
- between mild and moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild) and precuneus (mild)
- no degenerative or atrophic changes noted in the insular cortex
- no evidence of atrophy or degeneration in the occipital lobe
- no degenerative or atrophic changes noted in the frontal lobe
- temporal lobe presents with a healthy appearance, free from atrophy
For the subcortical structures:
- no signs of atrophy detected in the caudate
- basal forebrain remains normal, with no signs of tissue loss
- no signs of atrophy detected in the pallidum
- ventral dc maintains its normal morphology without atrophic features
- putamen appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the thalamus
- no observable atrophic alterations in the hippocampus
- no degenerative or atrophic changes noted in the amygdala
- between normal and mild atrophy of the accumbens, more pronounced on the right | CN |
ADNI_024_S_5054_MR_MPRAGE_br_raw_20121220180216980_73_S178405_I352573_dupl_3 | On a T1-weighted brain MRI of a 74-year-old female subject, we observed:
For the cerebral cortex:
- the parietal lobe shows no structural abnormalities indicative of atrophy
- the limbic cortex shows no structural abnormalities indicative of atrophy
- moderate bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: occipital fusiform gyrus (mild) and occipital pole (mild)
- no evidence of atrophy or degeneration in the temporal lobe
- no degenerative or atrophic changes noted in the frontal lobe
- the insular cortex shows no structural abnormalities indicative of atrophy
For the ventricles:
- between normal and mild left enlargement of the lateral ventricle
- no abnormal enlargement observed in the 4th ventricle
- between moderate and severe bilateral inf. lateral ventricle enlargement
- 3rd ventricle maintains its normal volume without signs of enlargement
- the external csf shows no structural abnormalities indicative of enlargement
For the subcortical structures:
- the accumbens shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the ventral dc
- no pathological changes consistent with atrophy detected in the thalamus
- putamen presents with a healthy appearance, free from atrophy
- amygdala maintains its normal morphology without atrophic features
- caudate presents with a healthy appearance, free from atrophy
- mild bilateral hippocampus atrophy
- basal forebrain appears structurally intact with no atrophic changes
- pallidum appears structurally intact with no atrophic changes | AD |
NIFD_2_S_0002_MR_MT1__GradWarp__N3m_Br_20111229184614074_S133938_I274719_dupl_2 | On a T1-weighted brain MRI of a 64-year-old male subject, we observed:
For the cerebral cortex:
- no observable atrophic alterations in the occipital lobe
- moderate atrophy of the insular cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (severe), posterior insula (between normal and mild) and frontal operculum (moderate)
- mild atrophy of the limbic cortex, more pronounced on the right, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe)
- no pathological changes consistent with atrophy detected in the parietal lobe
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: frontal pole (between moderate and severe), gyrus rectus (severe), opercular inf. frontal gyrus (between mild and moderate), medial frontal cortex (between mild and moderate), middle frontal gyrus (severe), anterior orbital gyrus (between moderate and severe), lateral orbital gyrus (severe), medial orbital gyrus (moderate), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus (moderate), sup. frontal gyrus medial segment (severe) and triangular inf. frontal gyrus (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in temporal pole (between normal and mild) and middle temporal gyrus (between normal and mild)
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
- between moderate and severe enlargement of the 3rd ventricle
- moderate enlargement of the external csf
- between mild and moderate enlargement of the lateral ventricle, more pronounced on the right
- 4th ventricle appears structurally intact, with no evidence of enlargement
For the subcortical structures:
- amygdala maintains its normal morphology without atrophic features
- mild atrophy of the thalamus, more pronounced on the right
- basal forebrain maintains its normal morphology without atrophic features
- severe bilateral pallidum atrophy, more pronounced on the right
- mild atrophy of the hippocampus, more pronounced on the right
- severe bilateral caudate atrophy, more pronounced on the right
- between normal and mild atrophy of the ventral dc, more pronounced on the right
- severe bilateral accumbens atrophy, more pronounced on the right
- severe bilateral putamen atrophy, more pronounced on the right | BV |
ADNI_130_S_5059_MR_MPRAGE_br_raw_20130212105012862_33_S182011_I358776_dupl_1 | On a T1-weighted brain MRI of a 73-year-old male subject, we observed:
For the subcortical structures:
- ventral dc presents with a healthy appearance, free from atrophy
- no degenerative or atrophic changes noted in the pallidum
- between normal and mild bilateral amygdala atrophy
- no pathological changes consistent with atrophy detected in the thalamus
- no observable atrophic alterations in the accumbens
- putamen presents with a healthy appearance, free from atrophy
- basal forebrain appears structurally intact with no atrophic changes
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- caudate remains normal, with no signs of tissue loss
For the ventricles:
- no abnormal enlargement observed in the lateral ventricle
- between moderate and severe bilateral inf. lateral ventricle enlargement
- between normal and mild enlargement of the 3rd ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
- no enlargement observed in the external csf
For the cerebral cortex:
- between mild and moderate bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: planum temporale (between normal and mild), inf. temporal gyrus (between normal and mild), middle temporal gyrus (mild) and sup. temporal gyrus (between normal and mild)
- no degenerative or atrophic changes noted in the insular cortex
- parietal lobe remains normal, with no signs of tissue loss
- no signs of atrophy detected in the frontal lobe
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle occipital gyrus (mild) and occipital fusiform gyrus (between normal and mild)
- no signs of atrophy detected in the limbic cortex | AD |
NIFD_1_S_0288_MR_t1_mprage__br_raw_20170814180736340_14_S594408_I886878_dupl_3 | On a T1-weighted brain MRI of a 64-year-old male subject, we observed:
For the subcortical structures:
- no degenerative or atrophic changes noted in the basal forebrain
- between mild and moderate bilateral caudate atrophy
- between normal and mild bilateral accumbens atrophy
- between normal and mild bilateral ventral dc atrophy
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- no evidence of atrophy or degeneration in the pallidum
- no degenerative or atrophic changes noted in the amygdala
- no observable atrophic alterations in the putamen
- thalamus remains normal, with no signs of tissue loss
For the cerebral cortex:
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (mild) and sup. temporal gyrus (between normal and mild)
- the occipital lobe shows no structural abnormalities indicative of atrophy
- no pathological changes consistent with atrophy detected in the insular cortex
- no pathological changes consistent with atrophy detected in the limbic cortex
- parietal lobe presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the frontal lobe
For the ventricles:
- 4th ventricle remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the external csf
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- no enlargement observed in the 3rd ventricle
- the lateral ventricle shows no structural abnormalities indicative of enlargement | CN |
NIFD_1_S_0235_MR_t1_mprage__br_raw_20160902135026421_139_S495650_I771798_dupl_3 | On a T1-weighted brain MRI of a 68-year-old female subject, we observed:
For the cerebral cortex:
- no degenerative or atrophic changes noted in the occipital lobe
- no pathological changes consistent with atrophy detected in the insular cortex
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (between mild and moderate) and sup. temporal gyrus (mild)
- parietal lobe presents with a healthy appearance, free from atrophy
- no degenerative or atrophic changes noted in the limbic cortex
- no evidence of atrophy or degeneration in the frontal lobe
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the putamen
- the caudate shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the thalamus
- mild bilateral hippocampus atrophy
- accumbens maintains its normal morphology without atrophic features
- pallidum remains normal, with no signs of tissue loss
- basal forebrain maintains its normal morphology without atrophic features
- amygdala remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the ventral dc
For the ventricles:
- inf. lateral ventricle is free from enlargement or excessive growth
- external csf remains within normal size parameters, with no enlargement detected
- 4th ventricle is free from enlargement or excessive growth
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- no pathological changes consistent with enlargement noted in the 3rd ventricle | CN |
NIFD_1_S_0279_MR_t1_mprage__br_raw_20160903204551965_44_S496713_I773020_dupl_2 | On a T1-weighted brain MRI of a 62-year-old female subject, we observed:
For the cerebral cortex:
- no observable atrophic alterations in the limbic cortex
- no observable atrophic alterations in the insular cortex
- parietal lobe maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the frontal lobe
- no pathological changes consistent with atrophy detected in the temporal lobe
- occipital lobe maintains its normal morphology without atrophic features
For the subcortical structures:
- no observable atrophic alterations in the putamen
- the accumbens shows no structural abnormalities indicative of atrophy
- pallidum maintains its normal morphology without atrophic features
- hippocampus presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the amygdala
- the basal forebrain shows no structural abnormalities indicative of atrophy
- no pathological changes consistent with atrophy detected in the thalamus
- no observable atrophic alterations in the caudate
- ventral dc appears structurally intact with no atrophic changes
For the ventricles:
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the external csf
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
- the lateral ventricle shows no structural abnormalities indicative of enlargement | CN |
ADNI_051_S_4980_MR_MPRAGE_br_raw_20121030084030420_50_S172619_I343041_dupl_4 | On a T1-weighted brain MRI of a 88-year-old male subject, we observed:
For the subcortical structures:
- pallidum maintains its normal morphology without atrophic features
- ventral dc presents with a healthy appearance, free from atrophy
- basal forebrain maintains its normal morphology without atrophic features
- thalamus appears structurally intact with no atrophic changes
- between normal and mild atrophy of the accumbens
- the putamen shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the amygdala
- mild left atrophy of the caudate
- hippocampus remains normal, with no signs of tissue loss
For the ventricles:
- no pathological changes consistent with enlargement noted in the lateral ventricle
- between normal and mild right enlargement of the inf. lateral ventricle
- mild enlargement of the 4th ventricle
- no observable enlargement or abnormal growth in the external csf
- 3rd ventricle maintains its normal volume without signs of enlargement
For the cerebral cortex:
- no evidence of atrophy or degeneration in the temporal lobe
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (between normal and mild) and postcentral gyrus (between normal and mild)
- between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: frontal operculum (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (between normal and mild), middle frontal gyrus (between normal and mild) and subcallosal area (between mild and moderate)
- occipital lobe appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the limbic cortex | AD |
NIFD_3_S_0011_MR_T1_mprage_ND_S3_DIS3D__br_raw_20160519104824325_34_S443835_I710941_dupl_3 | On a T1-weighted brain MRI of a 65-year-old male subject, we observed:
For the cerebral cortex:
- no evidence of atrophy or degeneration in the occipital lobe
- between normal and mild atrophy of the insular cortex, more pronounced on the left, with focal volume loss observed in the following subregions: posterior insula (between mild and moderate) and central operculum (mild)
- no signs of atrophy detected in the parietal lobe
- severe bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: planum polare (between mild and moderate), inf. temporal gyrus (between moderate and severe), middle temporal gyrus (between mild and moderate), sup. temporal gyrus (mild), temporal pole (severe) and fusiform gyrus (between normal and mild)
- severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (between moderate and severe), anterior cingulate gyrus (between normal and mild), middle cingulate gyrus (mild), posterior cingulate gyrus (between normal and mild) and parahippocampal gyrus (mild)
- frontal lobe presents with a healthy appearance, free from atrophy
For the subcortical structures:
- no signs of atrophy detected in the pallidum
- no observable atrophic alterations in the thalamus
- between mild and moderate bilateral accumbens atrophy, more pronounced on the left
- no signs of atrophy detected in the putamen
- between normal and mild atrophy of the caudate, more pronounced on the left
- no observable atrophic alterations in the basal forebrain
- no evidence of atrophy or degeneration in the ventral dc
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- severe bilateral amygdala atrophy, more pronounced on the left
For the ventricles:
- no observable enlargement or abnormal growth in the 4th ventricle
- between mild and moderate enlargement of the lateral ventricle, more pronounced on the left
- external csf maintains its normal volume without signs of enlargement
- mild enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the left | SV |
NIFD_1_S_0102_MR_T1_mprage_S3_DIS3D_br_raw_20170816161439198_36_S596667_I889712_dupl_2 | On a T1-weighted brain MRI of a 71-year-old male subject, we observed:
For the ventricles:
- mild enlargement of the 3rd ventricle
- mild left enlargement of the lateral ventricle
- severe enlargement of the external csf
- no abnormal enlargement observed in the 4th ventricle
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
For the subcortical structures:
- between moderate and severe bilateral putamen atrophy, more pronounced on the left
- between normal and mild left atrophy of the basal forebrain
- between normal and mild atrophy of the accumbens, more pronounced on the left
- between normal and mild atrophy of the amygdala
- severe bilateral pallidum atrophy, more pronounced on the left
- mild bilateral hippocampus atrophy
- severe bilateral ventral dc atrophy, more pronounced on the left
- severe bilateral thalamus atrophy, more pronounced on the left
- severe bilateral caudate atrophy, more pronounced on the left
For the cerebral cortex:
- mild atrophy of the limbic cortex, more pronounced on the left, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between mild and moderate) and middle cingulate gyrus (mild)
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (between mild and moderate), gyrus rectus (mild), middle frontal gyrus (severe), posterior orbital gyrus (between normal and mild), precentral gyrus (between moderate and severe), sup. frontal gyrus (mild) and supplementary motor cortex (mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (mild) and frontal operculum (mild)
- no evidence of atrophy or degeneration in the parietal lobe
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in fusiform gyrus (between normal and mild) and temporal pole (between normal and mild)
- no signs of atrophy detected in the occipital lobe | BV |
NIFD_1_S_0287_MR_t1_mprage__br_raw_20160903211742055_18_S496783_I773101_dupl_1 | On a T1-weighted brain MRI of a 64-year-old male subject, we observed:
For the subcortical structures:
- ventral dc appears structurally intact with no atrophic changes
- thalamus presents with a healthy appearance, free from atrophy
- accumbens maintains its normal morphology without atrophic features
- putamen remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the pallidum
- between normal and mild bilateral caudate atrophy
- no observable atrophic alterations in the amygdala
- no signs of atrophy detected in the basal forebrain
- no pathological changes consistent with atrophy detected in the hippocampus
For the ventricles:
- no abnormal enlargement observed in the lateral ventricle
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- the external csf shows no structural abnormalities indicative of enlargement
- no enlargement observed in the 4th ventricle
For the cerebral cortex:
- no observable atrophic alterations in the frontal lobe
- no pathological changes consistent with atrophy detected in the insular cortex
- limbic cortex maintains its normal morphology without atrophic features
- temporal lobe remains normal, with no signs of tissue loss
- no observable atrophic alterations in the occipital lobe
- the parietal lobe shows no structural abnormalities indicative of atrophy | CN |
NIFD_1_S_0356_MR_t1_mprage__br_raw_20170628174605905_151_S577026_I866521_dupl_3 | On a T1-weighted brain MRI of a 61-year-old female subject, we observed:
For the ventricles:
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- no enlargement observed in the lateral ventricle
- between normal and mild enlargement of the inf. lateral ventricle, more pronounced on the right
- severe enlargement of the external csf
- 4th ventricle appears structurally intact, with no evidence of enlargement
For the subcortical structures:
- ventral dc presents with a healthy appearance, free from atrophy
- mild right atrophy of the putamen
- severe bilateral accumbens atrophy, more pronounced on the right
- between normal and mild atrophy of the caudate, more pronounced on the right
- between normal and mild atrophy of the hippocampus, more pronounced on the right
- pallidum presents with a healthy appearance, free from atrophy
- severe bilateral amygdala atrophy, more pronounced on the right
- no signs of atrophy detected in the basal forebrain
- thalamus maintains its normal morphology without atrophic features
For the cerebral cortex:
- moderate bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (between mild and moderate), sup. temporal gyrus (mild) and temporal pole (between moderate and severe)
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (severe) and frontal operculum (between moderate and severe)
- no pathological changes consistent with atrophy detected in the occipital lobe
- severe bilateral frontal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: gyrus rectus (severe), opercular inf. frontal gyrus (between mild and moderate), orbital inf. frontal gyrus (between mild and moderate), triangular inf. frontal gyrus (mild), medial frontal cortex (severe), middle frontal gyrus (severe), anterior orbital gyrus (mild), lateral orbital gyrus (between moderate and severe), medial orbital gyrus (between mild and moderate), posterior orbital gyrus (between mild and moderate), sup. frontal gyrus (severe) and sup. frontal gyrus medial segment (moderate)
- between moderate and severe bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (severe) and posterior cingulate gyrus (between normal and mild)
- parietal lobe presents with a healthy appearance, free from atrophy | BV |
ADNI_126_S_4686_MR_Accelerated_Sag_IR-SPGR__br_raw_20120427123703300_117_S148519_I300822_dupl_2 | On a T1-weighted brain MRI of a 72-year-old male subject, we observed:
For the cerebral cortex:
- between normal and mild atrophy of the insular cortex, more pronounced on the right, with focal volume loss observed in the following subregions: central operculum (between mild and moderate)
- between normal and mild atrophy of the occipital lobe, with focal volume loss observed in the following subregions: calcarine cortex (mild) and lingual gyrus (between normal and mild)
- no signs of atrophy detected in the limbic cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (mild) and triangular inf. frontal gyrus (between normal and mild)
- no pathological changes consistent with atrophy detected in the temporal lobe
- no degenerative or atrophic changes noted in the parietal lobe
For the ventricles:
- no signs of enlargement detected in the inf. lateral ventricle
- between normal and mild enlargement of the external csf
- no abnormal enlargement observed in the 4th ventricle
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the lateral ventricle
For the subcortical structures:
- no observable atrophic alterations in the basal forebrain
- between moderate and severe bilateral amygdala atrophy
- between mild and moderate bilateral hippocampus atrophy, more pronounced on the left
- no signs of atrophy detected in the putamen
- no signs of atrophy detected in the thalamus
- accumbens remains normal, with no signs of tissue loss
- pallidum appears structurally intact with no atrophic changes
- caudate maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the ventral dc | AD |
NIFD_1_S_0309_MR_t1_mprage__br_raw_20160909134218398_83_S497944_I774495_dupl_1 | On a T1-weighted brain MRI of a 67-year-old male subject, we observed:
For the subcortical structures:
- no observable atrophic alterations in the amygdala
- between normal and mild left atrophy of the putamen
- no pathological changes consistent with atrophy detected in the basal forebrain
- ventral dc presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the caudate
- pallidum remains normal, with no signs of tissue loss
- accumbens maintains its normal morphology without atrophic features
- no signs of atrophy detected in the thalamus
- hippocampus presents with a healthy appearance, free from atrophy
For the ventricles:
- lateral ventricle appears structurally intact, with no evidence of enlargement
- between normal and mild enlargement of the 3rd ventricle
- no signs of enlargement detected in the 4th ventricle
- mild bilateral inf. lateral ventricle enlargement
- external csf remains within normal size parameters, with no enlargement detected
For the cerebral cortex:
- no evidence of atrophy or degeneration in the limbic cortex
- the insular cortex shows no structural abnormalities indicative of atrophy
- parietal lobe appears structurally intact with no atrophic changes
- occipital lobe presents with a healthy appearance, free from atrophy
- temporal lobe remains normal, with no signs of tissue loss
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in triangular inf. frontal gyrus (between normal and mild) and middle frontal gyrus (mild) | CN |
NIFD_1_S_0269_MR_t1_mprage__br_raw_20160902220526927_82_S496410_I772673_dupl_2 | On a T1-weighted brain MRI of a 63-year-old female subject, we observed:
For the subcortical structures:
- mild bilateral accumbens atrophy, more pronounced on the right
- amygdala presents with a healthy appearance, free from atrophy
- between normal and mild left atrophy of the thalamus
- no signs of atrophy detected in the ventral dc
- pallidum maintains its normal morphology without atrophic features
- hippocampus maintains its normal morphology without atrophic features
- basal forebrain remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the caudate
- between normal and mild left atrophy of the putamen
For the ventricles:
- lateral ventricle maintains its normal volume without signs of enlargement
- no abnormal enlargement observed in the 3rd ventricle
- between normal and mild enlargement of the external csf
- 4th ventricle is free from enlargement or excessive growth
- no observable enlargement or abnormal growth in the inf. lateral ventricle
For the cerebral cortex:
- no signs of atrophy detected in the temporal lobe
- no pathological changes consistent with atrophy detected in the parietal lobe
- no degenerative or atrophic changes noted in the frontal lobe
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (between normal and mild) and occipital fusiform gyrus (between mild and moderate)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between mild and moderate) and middle cingulate gyrus (between normal and mild)
- no degenerative or atrophic changes noted in the insular cortex | CN |
ADNI_136_S_4727_MR_MPRAGE_br_raw_20120606151218245_114_S153015_I308415_dupl_5 | On a T1-weighted brain MRI of a 74-year-old female subject, we observed:
For the subcortical structures:
- thalamus maintains its normal morphology without atrophic features
- ventral dc maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the basal forebrain
- accumbens presents with a healthy appearance, free from atrophy
- amygdala remains normal, with no signs of tissue loss
- caudate remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the putamen
- no observable atrophic alterations in the pallidum
- no evidence of atrophy or degeneration in the hippocampus
For the ventricles:
- 4th ventricle maintains its normal volume without signs of enlargement
- between normal and mild enlargement of the external csf
- lateral ventricle maintains its normal volume without signs of enlargement
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the 3rd ventricle
For the cerebral cortex:
- between normal and mild atrophy of the frontal lobe, with focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild) and middle frontal gyrus (between normal and mild)
- occipital lobe remains normal, with no signs of tissue loss
- no signs of atrophy detected in the limbic cortex
- temporal lobe presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the parietal lobe
- the insular cortex shows no structural abnormalities indicative of atrophy | CN |
ADNI_126_S_4686_MR_Accelerated_Sag_IR-SPGR__br_raw_20120427123703300_117_S148519_I300822_dupl_3 | On a T1-weighted brain MRI of a 72-year-old male subject, we observed:
For the cerebral cortex:
- between normal and mild atrophy of the insular cortex, more pronounced on the right, with focal volume loss observed in the following subregions: central operculum (between mild and moderate)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (mild) and triangular inf. frontal gyrus (between normal and mild)
- no signs of atrophy detected in the temporal lobe
- between normal and mild atrophy of the occipital lobe, with focal volume loss observed in the following subregions: calcarine cortex (mild) and lingual gyrus (between normal and mild)
- no observable atrophic alterations in the parietal lobe
- limbic cortex remains normal, with no signs of tissue loss
For the ventricles:
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- lateral ventricle maintains its normal volume without signs of enlargement
- 3rd ventricle is free from enlargement or excessive growth
- between normal and mild enlargement of the external csf
For the subcortical structures:
- ventral dc maintains its normal morphology without atrophic features
- basal forebrain presents with a healthy appearance, free from atrophy
- thalamus maintains its normal morphology without atrophic features
- the pallidum shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the putamen
- no pathological changes consistent with atrophy detected in the caudate
- between moderate and severe bilateral amygdala atrophy
- between mild and moderate bilateral hippocampus atrophy, more pronounced on the left
- no degenerative or atrophic changes noted in the accumbens | AD |
ADNI_130_S_5059_MR_MPRAGE_br_raw_20130212105012862_33_S182011_I358776_dupl_3 | On a T1-weighted brain MRI of a 73-year-old male subject, we observed:
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the limbic cortex
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle occipital gyrus (mild) and occipital fusiform gyrus (between normal and mild)
- no pathological changes consistent with atrophy detected in the insular cortex
- the frontal lobe shows no structural abnormalities indicative of atrophy
- parietal lobe presents with a healthy appearance, free from atrophy
- between mild and moderate bilateral temporal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: planum temporale (between normal and mild), inf. temporal gyrus (between normal and mild), middle temporal gyrus (mild) and sup. temporal gyrus (between normal and mild)
For the subcortical structures:
- no signs of atrophy detected in the putamen
- no signs of atrophy detected in the pallidum
- the basal forebrain shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the accumbens
- between normal and mild bilateral amygdala atrophy
- caudate remains normal, with no signs of tissue loss
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- ventral dc maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the thalamus
For the ventricles:
- between moderate and severe bilateral inf. lateral ventricle enlargement
- 4th ventricle maintains its normal volume without signs of enlargement
- no enlargement observed in the lateral ventricle
- between normal and mild enlargement of the 3rd ventricle
- no pathological changes consistent with enlargement noted in the external csf | AD |
ADNI_037_S_4028_MR_MPRAGE_br_raw_20110425125155063_168_S105075_I228854_dupl_4 | On a T1-weighted brain MRI of a 64-year-old female subject, we observed:
For the subcortical structures:
- pallidum remains normal, with no signs of tissue loss
- accumbens appears structurally intact with no atrophic changes
- no signs of atrophy detected in the thalamus
- between normal and mild atrophy of the hippocampus, more pronounced on the left
- no signs of atrophy detected in the basal forebrain
- no signs of atrophy detected in the amygdala
- ventral dc presents with a healthy appearance, free from atrophy
- between normal and mild bilateral putamen atrophy
- between normal and mild bilateral caudate atrophy
For the ventricles:
- no enlargement observed in the 3rd ventricle
- no signs of enlargement detected in the lateral ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
- no enlargement observed in the external csf
For the cerebral cortex:
- no evidence of atrophy or degeneration in the parietal lobe
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lingual gyrus (between normal and mild) and middle occipital gyrus (between mild and moderate)
- mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: parietal operculum (severe)
- no pathological changes consistent with atrophy detected in the temporal lobe
- the limbic cortex shows no structural abnormalities indicative of atrophy
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (mild) and subcallosal area (between normal and mild) | CN |
NIFD_1_S_0217_MR_T1_mprage_S3_DIS3D_br_raw_20170817134937636_129_S598229_I891831_dupl_1 | On a T1-weighted brain MRI of a 56-year-old male subject, we observed:
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in orbital inf. frontal gyrus (mild), posterior orbital gyrus (mild) and opercular inf. frontal gyrus (between normal and mild)
- parietal lobe presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the temporal lobe
- limbic cortex presents with a healthy appearance, free from atrophy
- mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild) and central operculum (between normal and mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in inf. occipital gyrus (mild) and sup. occipital gyrus (between normal and mild)
For the subcortical structures:
- basal forebrain presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the caudate
- no degenerative or atrophic changes noted in the pallidum
- the putamen shows no structural abnormalities indicative of atrophy
- ventral dc maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the hippocampus
- amygdala appears structurally intact with no atrophic changes
- thalamus presents with a healthy appearance, free from atrophy
- accumbens maintains its normal morphology without atrophic features
For the ventricles:
- between normal and mild enlargement of the external csf
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- no signs of enlargement detected in the 4th ventricle
- lateral ventricle maintains its normal volume without signs of enlargement | CN |
ADNI_116_S_4092_MR_MPRAGE_br_raw_20110624151136233_164_S112544_I241692_dupl_4 | On a T1-weighted brain MRI of a 82-year-old female subject, we observed:
For the ventricles:
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- no enlargement observed in the external csf
- no observable enlargement or abnormal growth in the 4th ventricle
- no abnormal enlargement observed in the 3rd ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
For the cerebral cortex:
- no signs of atrophy detected in the frontal lobe
- no pathological changes consistent with atrophy detected in the insular cortex
- occipital lobe appears structurally intact with no atrophic changes
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: posterior cingulate gyrus (between normal and mild)
- no signs of atrophy detected in the temporal lobe
- no evidence of atrophy or degeneration in the parietal lobe
For the subcortical structures:
- no degenerative or atrophic changes noted in the caudate
- amygdala appears structurally intact with no atrophic changes
- mild left atrophy of the basal forebrain
- no observable atrophic alterations in the pallidum
- no signs of atrophy detected in the hippocampus
- between normal and mild atrophy of the thalamus, more pronounced on the left
- putamen maintains its normal morphology without atrophic features
- accumbens maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the ventral dc | CN |
ADNI_137_S_4482_MR_MPRAGE_br_raw_20120216103107707_132_S140958_I285105_dupl_2 | On a T1-weighted brain MRI of a 78-year-old female subject, we observed:
For the cerebral cortex:
- limbic cortex appears structurally intact with no atrophic changes
- insular cortex remains normal, with no signs of tissue loss
- no signs of atrophy detected in the parietal lobe
- the temporal lobe shows no structural abnormalities indicative of atrophy
- occipital lobe appears structurally intact with no atrophic changes
- frontal lobe presents with a healthy appearance, free from atrophy
For the subcortical structures:
- pallidum remains normal, with no signs of tissue loss
- no signs of atrophy detected in the accumbens
- ventral dc presents with a healthy appearance, free from atrophy
- the hippocampus shows no structural abnormalities indicative of atrophy
- no pathological changes consistent with atrophy detected in the amygdala
- no pathological changes consistent with atrophy detected in the basal forebrain
- thalamus maintains its normal morphology without atrophic features
- no observable atrophic alterations in the caudate
- the putamen shows no structural abnormalities indicative of atrophy
For the ventricles:
- no observable enlargement or abnormal growth in the 3rd ventricle
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- 4th ventricle appears structurally intact, with no evidence of enlargement
- mild enlargement of the external csf
- lateral ventricle appears structurally intact, with no evidence of enlargement | CN |
ADNI_021_S_4718_MR_Accelerated_Sag_IR-SPGR__br_raw_20120516162344538_10_S150673_I304759_dupl_2 | On a T1-weighted brain MRI of a 79-year-old male subject, we observed:
For the cerebral cortex:
- insular cortex appears structurally intact with no atrophic changes
- limbic cortex appears structurally intact with no atrophic changes
- severe bilateral parietal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: angular gyrus (moderate), postcentral gyrus (mild), precuneus (mild) and supramarginal gyrus (between normal and mild)
- the occipital lobe shows no structural abnormalities indicative of atrophy
- the frontal lobe shows no structural abnormalities indicative of atrophy
- between moderate and severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (between mild and moderate), inf. temporal gyrus (between mild and moderate) and middle temporal gyrus (moderate)
For the ventricles:
- 4th ventricle is free from enlargement or excessive growth
- mild enlargement of the external csf
- lateral ventricle appears structurally intact, with no evidence of enlargement
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- severe bilateral inf. lateral ventricle enlargement, more pronounced on the right
For the subcortical structures:
- severe bilateral amygdala atrophy, more pronounced on the right
- between normal and mild right atrophy of the caudate
- mild bilateral accumbens atrophy
- between normal and mild atrophy of the hippocampus, more pronounced on the right
- no evidence of atrophy or degeneration in the basal forebrain
- no evidence of atrophy or degeneration in the pallidum
- ventral dc appears structurally intact with no atrophic changes
- mild right atrophy of the thalamus
- putamen appears structurally intact with no atrophic changes | AD |
NIFD_1_S_0097_MR_T1_mprage_S3_DIS3D_br_raw_20120819171037400_152_S161488_I324741_dupl_5 | On a T1-weighted brain MRI of a 69-year-old male subject, we observed:
For the subcortical structures:
- no evidence of atrophy or degeneration in the thalamus
- no evidence of atrophy or degeneration in the basal forebrain
- no observable atrophic alterations in the pallidum
- between normal and mild atrophy of the caudate, more pronounced on the right
- no observable atrophic alterations in the ventral dc
- severe bilateral accumbens atrophy, more pronounced on the right
- severe bilateral amygdala atrophy, more pronounced on the right
- mild right atrophy of the putamen
- moderate bilateral hippocampus atrophy, more pronounced on the right
For the cerebral cortex:
- severe bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (between moderate and severe), planum polare (between normal and mild), inf. temporal gyrus (severe), middle temporal gyrus (severe), sup. temporal gyrus (mild) and temporal pole (severe)
- frontal lobe appears structurally intact with no atrophic changes
- parietal lobe remains normal, with no signs of tissue loss
- mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (severe) and parahippocampal gyrus (moderate)
- insular cortex maintains its normal morphology without atrophic features
- occipital lobe presents with a healthy appearance, free from atrophy
For the ventricles:
- 4th ventricle appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the lateral ventricle
- severe bilateral inf. lateral ventricle enlargement
- between normal and mild enlargement of the external csf
- no pathological changes consistent with enlargement noted in the 3rd ventricle | SV |
ADNI_037_S_5162_MR_MPRAGE_br_raw_20130503091904515_4_S188623_I369977_dupl_1 | On a T1-weighted brain MRI of a 70-year-old male subject, we observed:
For the cerebral cortex:
- limbic cortex appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the occipital lobe
- between mild and moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (between mild and moderate)
- no pathological changes consistent with atrophy detected in the parietal lobe
- between normal and mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (between normal and mild) and middle temporal gyrus (between normal and mild)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (between normal and mild), orbital inf. frontal gyrus (mild) and posterior orbital gyrus (mild)
For the ventricles:
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- between normal and mild enlargement of the 3rd ventricle
- no observable enlargement or abnormal growth in the 4th ventricle
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- no pathological changes consistent with enlargement noted in the external csf
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the ventral dc
- the pallidum shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the basal forebrain
- the thalamus shows no structural abnormalities indicative of atrophy
- between normal and mild left atrophy of the putamen
- between normal and mild right atrophy of the caudate
- no evidence of atrophy or degeneration in the hippocampus
- between normal and mild right atrophy of the amygdala
- accumbens remains normal, with no signs of tissue loss | AD |
ADNI_006_S_4192_MR_MPRAGE_br_raw_20110928083832513_147_S123807_I258594_dupl_1 | On a T1-weighted brain MRI of a 83-year-old male subject, we observed:
For the cerebral cortex:
- temporal lobe appears structurally intact with no atrophic changes
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. frontal gyrus (moderate) and supplementary motor cortex (between normal and mild)
- the occipital lobe shows no structural abnormalities indicative of atrophy
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (between mild and moderate) and parahippocampal gyrus (between mild and moderate)
- insular cortex maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the parietal lobe
For the subcortical structures:
- pallidum maintains its normal morphology without atrophic features
- moderate bilateral amygdala atrophy, more pronounced on the left
- between normal and mild left atrophy of the hippocampus
- ventral dc appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the caudate
- between normal and mild right atrophy of the putamen
- between normal and mild left atrophy of the basal forebrain
- no observable atrophic alterations in the accumbens
- no pathological changes consistent with atrophy detected in the thalamus
For the ventricles:
- mild bilateral inf. lateral ventricle enlargement
- between mild and moderate bilateral lateral ventricle enlargement
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- external csf appears structurally intact, with no evidence of enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected | AD |
NIFD_1_S_0212_MR_T1_mprage_S3_DIS3D_br_raw_20170817105545257_129_S597537_I890918_dupl_1 | On a T1-weighted brain MRI of a 53-year-old female subject, we observed:
For the ventricles:
- mild enlargement of the 3rd ventricle
- lateral ventricle remains within normal size parameters, with no enlargement detected
- mild enlargement of the 4th ventricle
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no enlargement observed in the external csf
For the cerebral cortex:
- no degenerative or atrophic changes noted in the occipital lobe
- parietal lobe presents with a healthy appearance, free from atrophy
- limbic cortex appears structurally intact with no atrophic changes
- the temporal lobe shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the frontal lobe
- insular cortex presents with a healthy appearance, free from atrophy
For the subcortical structures:
- no degenerative or atrophic changes noted in the amygdala
- between normal and mild right atrophy of the ventral dc
- no signs of atrophy detected in the hippocampus
- mild bilateral pallidum atrophy
- putamen appears structurally intact with no atrophic changes
- basal forebrain remains normal, with no signs of tissue loss
- thalamus appears structurally intact with no atrophic changes
- caudate remains normal, with no signs of tissue loss
- the accumbens shows no structural abnormalities indicative of atrophy | CN |
ADNI_073_S_4853_MR_MPRAGE_br_raw_20120711181405636_32_S157321_I315948_dupl_2 | On a T1-weighted brain MRI of a 71-year-old female subject, we observed:
For the subcortical structures:
- mild bilateral ventral dc atrophy
- mild atrophy of the amygdala, more pronounced on the right
- basal forebrain maintains its normal morphology without atrophic features
- mild atrophy of the hippocampus, more pronounced on the right
- no pathological changes consistent with atrophy detected in the caudate
- the thalamus shows no structural abnormalities indicative of atrophy
- mild bilateral accumbens atrophy, more pronounced on the right
- pallidum presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the putamen
For the cerebral cortex:
- no observable atrophic alterations in the parietal lobe
- mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between normal and mild)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior insula (mild) and central operculum (mild)
- between mild and moderate bilateral temporal lobe atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: fusiform gyrus (between normal and mild), middle temporal gyrus (between mild and moderate) and sup. temporal gyrus (mild)
- occipital lobe remains normal, with no signs of tissue loss
- between mild and moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: posterior orbital gyrus (between normal and mild), precentral gyrus medial segment (between normal and mild), sup. frontal gyrus (mild), sup. frontal gyrus medial segment (mild) and lateral orbital gyrus (between normal and mild)
For the ventricles:
- no signs of enlargement detected in the lateral ventricle
- between moderate and severe enlargement of the external csf
- between normal and mild enlargement of the 4th ventricle
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- between normal and mild right enlargement of the inf. lateral ventricle | AD |
ADNI_041_S_4060_MR_MPRAGE_br_raw_20110601153106894_30_S110364_I238383_dupl_3 | On a T1-weighted brain MRI of a 85-year-old male subject, we observed:
For the cerebral cortex:
- no evidence of atrophy or degeneration in the insular cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior orbital gyrus (between normal and mild) and subcallosal area (mild)
- occipital lobe maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the parietal lobe
- limbic cortex presents with a healthy appearance, free from atrophy
- temporal lobe presents with a healthy appearance, free from atrophy
For the ventricles:
- the external csf shows no structural abnormalities indicative of enlargement
- no enlargement observed in the inf. lateral ventricle
- no abnormal enlargement observed in the 4th ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
- 3rd ventricle is free from enlargement or excessive growth
For the subcortical structures:
- no evidence of atrophy or degeneration in the pallidum
- thalamus maintains its normal morphology without atrophic features
- accumbens remains normal, with no signs of tissue loss
- amygdala remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the hippocampus
- no signs of atrophy detected in the basal forebrain
- caudate remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the ventral dc
- no degenerative or atrophic changes noted in the putamen | CN |
NIFD_2_S_0014_MR_MT1__GradWarp__N3m_Br_20111229191004875_S134530_I274739_dupl_4 | On a T1-weighted brain MRI of a 53-year-old male subject, we observed:
For the ventricles:
- severe bilateral lateral ventricle enlargement
- between mild and moderate enlargement of the 4th ventricle
- mild enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement
- severe enlargement of the external csf
For the cerebral cortex:
- between moderate and severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (mild), opercular inf. frontal gyrus (between normal and mild), middle frontal gyrus (mild), lateral orbital gyrus (between normal and mild), posterior orbital gyrus (between moderate and severe), sup. frontal gyrus (mild) and medial frontal cortex (between normal and mild)
- mild atrophy of the temporal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: sup. temporal gyrus (mild) and temporal pole (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (mild) and middle occipital gyrus (mild)
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: anterior cingulate gyrus (between mild and moderate)
- between moderate and severe bilateral parietal lobe atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: angular gyrus (between normal and mild), precuneus (between normal and mild), sup. parietal lobule (moderate) and supramarginal gyrus (between mild and moderate)
- severe bilateral insular cortex atrophy, more pronounced on the right, with focal volume loss observed in the following subregions: anterior insula (between mild and moderate), central operculum (moderate) and parietal operculum (between normal and mild)
For the subcortical structures:
- severe bilateral accumbens atrophy, more pronounced on the left
- between moderate and severe bilateral putamen atrophy
- severe bilateral caudate atrophy
- between mild and moderate bilateral amygdala atrophy
- between normal and mild atrophy of the thalamus
- between normal and mild right atrophy of the hippocampus
- moderate bilateral pallidum atrophy
- ventral dc appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the basal forebrain | BV |
ADNI_003_S_4136_MR_Accelerated_SAG_IR-SPGR__br_raw_20110811161151865_120_S118498_I250168_dupl_2 | On a T1-weighted brain MRI of a 67-year-old male subject, we observed:
For the subcortical structures:
- between normal and mild atrophy of the accumbens
- moderate bilateral amygdala atrophy, more pronounced on the right
- ventral dc remains normal, with no signs of tissue loss
- basal forebrain presents with a healthy appearance, free from atrophy
- pallidum remains normal, with no signs of tissue loss
- mild bilateral hippocampus atrophy, more pronounced on the right
- no evidence of atrophy or degeneration in the thalamus
- between normal and mild left atrophy of the caudate
- between normal and mild atrophy of the putamen, more pronounced on the left
For the cerebral cortex:
- between normal and mild atrophy of the limbic cortex, with focal volume loss observed in the following subregions: posterior cingulate gyrus (mild)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (between normal and mild) and inf. occipital gyrus (between normal and mild)
- between normal and mild atrophy of the insular cortex, with focal volume loss observed in the following subregions: central operculum (between mild and moderate)
- mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (between normal and mild), posterior orbital gyrus (mild), precentral gyrus (between normal and mild) and sup. frontal gyrus (between normal and mild)
- between normal and mild atrophy of the parietal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: precuneus (mild) and supramarginal gyrus (between normal and mild)
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (moderate)
For the ventricles:
- severe bilateral inf. lateral ventricle enlargement
- between normal and mild enlargement of the 3rd ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
- no observable enlargement or abnormal growth in the external csf
- severe bilateral lateral ventricle enlargement | AD |
ADNI_031_S_4024_MR_MPRAGE_br_raw_20110425135648715_88_S105088_I228879_dupl_4 | On a T1-weighted brain MRI of a 56-year-old female subject, we observed:
For the cerebral cortex:
- between normal and mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (mild) and middle temporal gyrus (between mild and moderate)
- no signs of atrophy detected in the limbic cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (between normal and mild) and sup. frontal gyrus (moderate)
- the occipital lobe shows no structural abnormalities indicative of atrophy
- no pathological changes consistent with atrophy detected in the insular cortex
- between normal and mild atrophy of the parietal lobe, with focal volume loss observed in the following subregions: postcentral gyrus (between normal and mild)
For the ventricles:
- no abnormal enlargement observed in the inf. lateral ventricle
- no enlargement observed in the 4th ventricle
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- mild enlargement of the lateral ventricle, more pronounced on the right
- no pathological changes consistent with enlargement noted in the external csf
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the pallidum
- no evidence of atrophy or degeneration in the accumbens
- caudate remains normal, with no signs of tissue loss
- between mild and moderate bilateral hippocampus atrophy
- no pathological changes consistent with atrophy detected in the basal forebrain
- ventral dc appears structurally intact with no atrophic changes
- putamen remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the thalamus
- mild bilateral amygdala atrophy, more pronounced on the left | AD |
NIFD_1_S_0266_MR_t1_mprage__br_raw_20160902212027546_148_S496336_I772588_dupl_3 | On a T1-weighted brain MRI of a 68-year-old female subject, we observed:
For the cerebral cortex:
- insular cortex presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the limbic cortex
- temporal lobe presents with a healthy appearance, free from atrophy
- between normal and mild atrophy of the occipital lobe, with focal volume loss observed in the following subregions: calcarine cortex (between normal and mild) and lingual gyrus (between normal and mild)
- no signs of atrophy detected in the parietal lobe
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (between normal and mild) and sup. frontal gyrus (between normal and mild)
For the subcortical structures:
- between normal and mild atrophy of the hippocampus, more pronounced on the right
- no observable atrophic alterations in the ventral dc
- no pathological changes consistent with atrophy detected in the amygdala
- no signs of atrophy detected in the accumbens
- no observable atrophic alterations in the thalamus
- the putamen shows no structural abnormalities indicative of atrophy
- basal forebrain appears structurally intact with no atrophic changes
- pallidum appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the caudate
For the ventricles:
- no abnormal enlargement observed in the 4th ventricle
- external csf maintains its normal volume without signs of enlargement
- no enlargement observed in the 3rd ventricle
- between mild and moderate bilateral lateral ventricle enlargement, more pronounced on the right
- no abnormal enlargement observed in the inf. lateral ventricle | CN |
ADNI_123_S_4526_MR_MPRAGE_br_raw_20120209093528861_37_S140267_I283603_dupl_4 | On a T1-weighted brain MRI of a 80-year-old male subject, we observed:
For the cerebral cortex:
- no degenerative or atrophic changes noted in the frontal lobe
- mild atrophy of the temporal lobe, with focal volume loss observed in the following subregions: inf. temporal gyrus (between normal and mild) and sup. temporal gyrus (between normal and mild)
- no evidence of atrophy or degeneration in the occipital lobe
- no observable atrophic alterations in the insular cortex
- the limbic cortex shows no structural abnormalities indicative of atrophy
- parietal lobe presents with a healthy appearance, free from atrophy
For the subcortical structures:
- no observable atrophic alterations in the basal forebrain
- between moderate and severe bilateral amygdala atrophy, more pronounced on the left
- thalamus remains normal, with no signs of tissue loss
- no evidence of atrophy or degeneration in the ventral dc
- between normal and mild left atrophy of the caudate
- no evidence of atrophy or degeneration in the putamen
- no signs of atrophy detected in the accumbens
- mild atrophy of the hippocampus, more pronounced on the left
- no evidence of atrophy or degeneration in the pallidum
For the ventricles:
- external csf remains within normal size parameters, with no enlargement detected
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the lateral ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
- no enlargement observed in the inf. lateral ventricle | AD |
NIFD_1_S_0169_MR_T1_mprage_S3_DIS3D_br_raw_20140701110602779_92_S223672_I433733_dupl_3 | On a T1-weighted brain MRI of a 74-year-old female subject, we observed:
For the ventricles:
- no signs of enlargement detected in the external csf
- no signs of enlargement detected in the lateral ventricle
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- no pathological changes consistent with enlargement noted in the 4th ventricle
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the parietal lobe
- between mild and moderate bilateral insular cortex atrophy, more pronounced on the left, with focal volume loss observed in the following subregions: anterior insula (between normal and mild), central operculum (between mild and moderate) and posterior insula (between normal and mild)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (between mild and moderate), sup. temporal gyrus (between mild and moderate) and transverse temporal gyrus (between normal and mild)
- the limbic cortex shows no structural abnormalities indicative of atrophy
- between normal and mild atrophy of the frontal lobe, more pronounced on the right, with focal volume loss observed in the following subregions: sup. frontal gyrus (moderate)
- no pathological changes consistent with atrophy detected in the occipital lobe
For the subcortical structures:
- the basal forebrain shows no structural abnormalities indicative of atrophy
- accumbens presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the thalamus
- moderate bilateral hippocampus atrophy, more pronounced on the right
- caudate maintains its normal morphology without atrophic features
- amygdala appears structurally intact with no atrophic changes
- putamen remains normal, with no signs of tissue loss
- pallidum maintains its normal morphology without atrophic features
- ventral dc remains normal, with no signs of tissue loss | PNFA |
End of preview. Expand
in Data Studio
README.md exists but content is empty.
- Downloads last month
- 0