Title stringlengths 0 905 | Abstract stringlengths 0 11.3k | Container_Title stringlengths 0 126 | Subject listlengths 1 13 |
|---|---|---|---|
The Effect of Cottonseed in the Ration on Percentage of Fat and Serum Solids Content of Milk | Journal of Dairy Science | [
"Genetics",
"Animal Science and Zoology",
"Food Science"
] | |
Simplifying assessment of forest management practices for invertebrates: How effective are higher taxon and habitat surrogates for spiders following prescribed burning? | Forest Ecology and Management | [
"Management, Monitoring, Policy and Law",
"Nature and Landscape Conservation",
"Forestry"
] | |
Methane emissions of major economies in 2014: A household-consumption-based perspective | [
"Pollution",
"Waste Management and Disposal",
"Environmental Chemistry",
"Environmental Engineering"
] | ||
Alkaline comet assay in rainbow trout hepatocytes | [
"Toxicology"
] | ||
Diversity of governance arrangements for indigenous natural products in communal areas of Namibia | [
"Forestry"
] | ||
The conservative management of adolescent idiopathic scoliosis | [
"Rehabilitation",
"Orthopedics and Sports Medicine",
"Physical Therapy, Sports Therapy and Rehabilitation"
] | ||
Book Reviews | [
"Geriatrics and Gerontology",
"History"
] | ||
Electrochemical sensor based on reduced graphene oxide and molecularly imprinted poly(phenol) for d-xylose determination | [
"Analytical Chemistry"
] | ||
Classic Kaposi's sarcoma treated with topical rapamycin | Dermatologic Therapy | [
"Dermatology"
] | |
The Joint Signature of Coherent Systems with Shared Components | System signatures are useful tools in the study and comparison of coherent systems. In this paper, we define and study a similar concept, called the joint signature, for two coherent systems which share some components. Under an independent and identically distributed assumption on component lifetimes, a pseudo-mixture representation based on this joint signature is obtained for the joint distribution of the lifetimes of both systems. Sufficient conditions are given based on the respective joint signatures of two pairs of systems, each with shared components, to ensure various forms of bivariate stochastic orderings between the joint lifetimes of the two pairs of systems. | [
"Statistics, Probability and Uncertainty",
"Statistics and Probability"
] | |
Front cover | Food & Function | [
"Food Science"
] | |
Shielding Benchmarks Analysis for Transport/Storage Casks | [
"Nuclear Energy and Engineering",
"Nuclear and High Energy Physics"
] | ||
Enhancement of volcanism and geothermal heat flux by ice‐age cycling: A stress modeling study of Greenland | [
"Earth-Surface Processes",
"Geophysics"
] | ||
Effect of Stress-free Therapy on Cerebral Blood Flow: Comparisons among patients with metabolic cardiovascular disease, healthy subjects and placebo-treated subjects | [
"Biomedical Engineering",
"Surgery"
] | ||
Clopidogrel prevents platelet aggregation and cyclic flow variations in stenosed and endothelium-injured canine coronary arteries | [
"Cardiology and Cardiovascular Medicine"
] | ||
Still In-Yer-Face? Towards a Critique and a Summation | The dramatic upsurge of contemporary new writing on British stages in the past decade, and the emergence of a fresh generation of playwrights led by such talents as Mark Ravenhill, Philip Ridley, Joe Penhall, Phyllis Nagy, Patrick Marber, and the late Sarah Kane, has been variously characterized as the ‘New Brutalism’ or even, in Germany, as the ‘Blood and Sperm Generation’. Here, Aleks Sierz summarizes the argument for ‘In-Yer-Face Theatre’ as the most pertinent and inclusive description for the phenomenon, listing its salient characteristics and suggesting the areas in which it is most vulnerable to criticism. Aleks Sierz is theatre critic of Tribune and writes about theatre for several publications. He is the author of In-Yer-Face Theatre: British Drama Today (London: Faber, 2001) and teaches journalism at Goldsmiths College, University of London. An earlier version of this article was given as a paper at the In-Yer-Face Theatre: Sarah Kane and the New British Dramaturgy conference at Stendhal University 3, Grenoble, in May 2001. | [
"Visual Arts and Performing Arts"
] | |
The Detection of Acute HIV Infection | [
"Infectious Diseases",
"Immunology and Allergy"
] | ||
Themes in the Historical Geography of France | [
"Museology",
"Archeology",
"History"
] | ||
Is what you hear what you see, even in a foreign language? | The Journal of the Acoustical Society of America | [
"Acoustics and Ultrasonics",
"Arts and Humanities (miscellaneous)"
] | |
Far-infrared spectrum, conformational stability, barriers to internal rotation, ab initio calculations, and vibrational assignment of propionyl bromide | Journal of Molecular Structure | [
"Inorganic Chemistry",
"Organic Chemistry",
"Spectroscopy",
"Analytical Chemistry"
] | |
Efficient computation of the Fourier transform on finite groups | Let G G be a finite group, f : G → C f:G \to {\mathbf {C | [
"Applied Mathematics"
] | |
Height benefit of GnRH agonists after age 8 in a Portuguese cohort of central precocious puberty | Clinical Endocrinology | [
"Endocrinology, Diabetes and Metabolism",
"Endocrinology"
] | |
X-band Operations Metamaterial Absorber with Extended Circular Ring Topology for Size Reduction | A metamaterial electromagnetic wave absorber consisting of a big circular ring patch with four smaller suppression circular rings is presented in this report. The metamaterial electromagnetic wave absorber introduces the concept of size reduction by suppressing the resonance frequency. An FR4 substrate was used and the incidental wave angles were varied from 00 to 600. Simulations results shows peak absorption of 100% was achieved at 10.7 GHz by the absorber for both TE and TM polarization incident waves. Minimum absorption for both TE and TM mode of 90.6% was achieved under TE mode. The metamaterial absorber was being tested with and Ultra-wide band antenna and the results were reported. | Indonesian Journal of Electrical Engineering and Computer Science | [
"Electrical and Electronic Engineering",
"Control and Optimization",
"Computer Networks and Communications",
"Hardware and Architecture",
"Information Systems",
"Signal Processing"
] |
MASS AND HOT BARYONS IN MASSIVE GALAXY CLUSTERS FROM SUBARU WEAK-LENSING AND AMiBA SUNYAEV-ZEL'DOVICH EFFECT OBSERVATIONS | [
"Space and Planetary Science",
"Astronomy and Astrophysics"
] | ||
Motor Unit Firing Rate And Nerve Conduction Velocity In Type 1 Diabetes In Response To A Fatigue Protocol | Medicine & Science in Sports & Exercise | [
"Physical Therapy, Sports Therapy and Rehabilitation",
"Orthopedics and Sports Medicine"
] | |
Human judgments of relative 3D pose of novel complex objects | [
"Sensory Systems",
"Ophthalmology"
] | ||
„Zwischen allen Stühlen?“ Die Behandlung Alkoholabhängiger zwischen Praxis, Psychiatrie und Somatischem Krankenhaus. Erkennen und Beseitigung von Fallstricken, Möglichkeiten der Zusammenarbeit | [
"Psychiatry and Mental Health",
"Applied Psychology"
] | ||
Coconut shell carbon nanosheets facilitating electron transfer for highly efficient visible-light-driven photocatalytic hydrogen production from water | [
"Energy Engineering and Power Technology",
"Condensed Matter Physics",
"Fuel Technology",
"Renewable Energy, Sustainability and the Environment"
] | ||
Association study of catechol-O-methyltransferase (COMT) gene Val158Met polymorphism with auditory P300 in Chinese Han patients with schizophrenia | [
"Biological Psychiatry",
"Psychiatry and Mental Health"
] | ||
Observing electron motion in molecules | [
"Condensed Matter Physics",
"Atomic and Molecular Physics, and Optics"
] | ||
High temperature superconductivity | Futures | [
"Sociology and Political Science",
"Development",
"Business and International Management"
] | |
Dynamic coarse-graining approach to quantum field theory | [
"Nuclear and High Energy Physics"
] | ||
ADMET evaluation in drug discovery. 20. Prediction of breast cancer resistance protein inhibition through machine learning | AbstractBreast cancer resistance protein (BCRP/ABCG2), an ATP-binding cassette (ABC) efflux transporter, plays a critical role in multi-drug resistance (MDR) to anti-cancer drugs and drug–drug interactions. The prediction of BCRP inhibition can facilitate evaluating potential drug resistance and drug–drug interactions in early stage of drug discovery. Here we reported a structurally diverse dataset consisting of 1098 BCRP inhibitors and 1701 non-inhibitors. Analysis of various physicochemical properties illustrates that BCRP inhibitors are more hydrophobic and aromatic than non-inhibitors. We then developed a series of quantitative structure–activity relationship (QSAR) models to discriminate between BCRP inhibitors and non-inhibitors. The optimal feature subset was determined by a wrapper feature selection method named rfSA (simulated annealing algorithm coupled with random forest), and the classification models were established by using seven machine learning approaches based on the optimal feature subset, including a deep learning method, two ensemble learning methods, and four classical machine learning methods. The statistical results demonstrated that three methods, including support vector machine (SVM), deep neural networks (DNN) and extreme gradient boosting (XGBoost), outperformed the others, and the SVM classifier yielded the best predictions (MCC = 0.812 and AUC = 0.958 for the test set). Then, a perturbation-based model-agnostic method was used to interpret our models and analyze the representative features for different models. The application domain analysis demonstrated the prediction reliability of our models. Moreover, the important structural fragments related to BCRP inhibition were identified by the information gain (IG) method along with the frequency analysis. In conclusion, we believe that the classification models developed in this study can be regarded as simple and accurate tools to distinguish BCRP inhibitors from non-inhibitors in drug design and discovery pipelines. | [
"Library and Information Sciences",
"Computer Graphics and Computer-Aided Design",
"Physical and Theoretical Chemistry",
"Computer Science Applications"
] | |
Cardiac arrhythmias: The quest for a cure | Journal of the American College of Cardiology | [
"Cardiology and Cardiovascular Medicine"
] | |
Cytokine mRNA levels in unmanipulated (ex vivo) and in vitro stimulated monkey PBMCs using a semi-quantitative RT-PCR and high sensitivity fluorescence-based detection strategy | Cytokine | [
"Molecular Biology",
"Hematology",
"Biochemistry",
"Immunology",
"Immunology and Allergy"
] | |
Ultrasound in twin pregnancy | [
"Obstetrics and Gynecology",
"Pediatrics, Perinatology and Child Health"
] | ||
Comparative analysis of differentially expressed miRNAs related to uterine involution in the ovine ovary and uterus | Abstract. To examine the possible miRNA molecular regulatory mechanisms during maternal uterine involution after delivery, we selected ovary and uterus tissues that are structurally connected as experimental materials. We employed Illumina HiSeq sequencing to screen and analyze the quantity and characteristics of miRNA in postpartum ewes in the methylergometrine-treated group and physiological saline control group. Results showed that 16 miRNAs were identified in the ovary libraries, including 4 known miRNAs and 12 novel miRNAs. In the uterus libraries, 54 miRNAs were identified, which included 5 known miRNAs and 49 novel miRNAs. At the same time, target gene prediction, GO annotation, and KEGG signaling pathway enrichment analysis were employed. We found that maternal uterine involution after delivery may involve two miRNA-target gene pairs, i.e., miRNA-200a-ZEB1 and YAP1. The YAP1/Hippo signaling pathway is used to construct an ovary–uterine axial regulatory mechanism to regulate the restoration of postpartum maternal uterine morphology and function. In view of this, the identification of miRNAs with significant differences in this study fills a gap in research on miRNAs associated with regulation of postpartum uterine recovery in ewes and provided an important reference for comprehensive understanding and in-depth research on the regulatory molecular network mechanism for postpartum uterine involution in small ruminants. | [
"Religious Studies",
"Cultural Studies"
] | |
The Ionization Constant of Sulfamic Acid from Electromotive Force Measurements | [
"Colloid and Surface Chemistry",
"Biochemistry",
"Catalysis"
] | ||
The Formation of the Wisconsin Progressive Party in 1934 | [
"History"
] | ||
Issue Information | Plastics Engineering | [
"Materials Chemistry",
"Polymers and Plastics"
] | |
Dürers Nashorn und die Nahrung vonEresus cinnberinus(Olivier) (Araneae: Eresidae) | Arachnologische Mitteilungen | [
"Insect Science",
"Ecology, Evolution, Behavior and Systematics"
] | |
KINGSFORD SMITH AIRPORT, SYDNEY: PLANNING AND TENDERING THE NEW PARALLEL RUNWAY. DISCUSSION. | Proceedings of the Institution of Civil Engineers - Civil Engineering | [
"Civil and Structural Engineering"
] | |
Comparison of the Measured Values between EEG-entropy and BIS during General Anesthesia and Sedation | [
"Anesthesiology and Pain Medicine"
] | ||
Reduction of Drooling with Scopolamine Ointment in Two Cases of Dysphagia | Practica oto-rhino-laryngologica. Suppl. | [
"Otorhinolaryngology"
] | |
Commentary: Know your enemy—Understanding futility in the battle against malignant pleural mesothelioma | The Journal of Thoracic and Cardiovascular Surgery | [
"Cardiology and Cardiovascular Medicine",
"Pulmonary and Respiratory Medicine",
"Surgery"
] | |
William James's Psychology of Philosophizing: Intellectual Diversity, Selective Attention, and the Sentiments in Our Rationalities | American psychologist and philosopher William James (1842–1910) developed a mediating path to understand and cope with intellectual disagreement. This template did not come to him any more easily than it would for anyone dealing with the contemporary challenges of deep cultural and political polarization. Although the compelling contrasts he experienced in his young adulthood, especially the competing commitments of science and religion, initially filled him with indecision and discouragement, he later synthesized the parts of his education into a platform for comprehending intellectual differences in relation to each other. James's approach to intellectual differences can be summarized with “three Rs”: the psychological roots of intellectual differences, their relations to each other, and effective ways to respond to them. James's ideas offer an education in strategies for coping with disagreement based on understanding how differences emerge to encourage searching for bridges across diversity. | [
"Philosophy",
"Sociology and Political Science"
] | |
The SP19 chronology for the South Pole Ice Core – Part 1: volcanic matching and annual layer counting | Abstract. The South Pole Ice Core (SPICEcore) was drilled in 2014–2016 to provide a detailed multi-proxy archive of paleoclimate conditions in East Antarctica during the Holocene and late Pleistocene. Interpretation of these records requires an accurate depth–age relationship. Here, we present the SPICEcore (SP19) timescale for the age of the ice of SPICEcore. SP19 is synchronized to the WD2014 chronology from the West Antarctic Ice Sheet Divide (WAIS Divide) ice core using stratigraphic matching of 251 volcanic events. These events indicate an age of 54 302±519 BP (years before 1950) at the bottom of SPICEcore. Annual layers identified in sodium and magnesium ions to 11 341 BP were used to interpolate between stratigraphic volcanic tie points, yielding an annually resolved chronology through the Holocene. Estimated timescale uncertainty during the Holocene is less than 18 years relative to WD2014, with the exception of the interval between 1800 to 3100 BP when uncertainty estimates reach ±25 years due to widely spaced volcanic tie points. Prior to the Holocene, uncertainties remain within 124 years relative to WD2014. Results show an average Holocene accumulation rate of 7.4 cm yr−1 (water equivalent). The time variability of accumulation rate is consistent with expectations for steady-state ice flow through the modern spatial pattern of accumulation rate. Time variations in nitrate concentration, nitrate seasonal amplitude and δ15N of N2 in turn are as expected for the accumulation rate variations. The highly variable yet well-constrained Holocene accumulation history at the site can help improve scientific understanding of deposition-sensitive climate proxies such as δ15N of N2 and photolyzed chemical compounds. | [
"Paleontology",
"Stratigraphy",
"Global and Planetary Change"
] | |
Conflicts Between Student/Professional, Parental, and Self-Development Roles: A Comparison of High and Low Effective Copers | This study investigated the coping strategies used by returning university students in dealing with conflicts between the demands of their students/professional role and their parental role or their student/professional role and their "self" as a self-actualized person. The 57 female and 28 male subjects used nine scales developed by the authors to describe their typical strategies for coping with their role conflict in one of these two areas. Subjects also rated the degree of role conflict experienced and the effectiveness of their coping strategies. As predicted, subjects rating their characteristic ways of coping as highly effective [High Effective Copers] reported less conflict and endorsed different coping strategies than subjects rating their characteristic strategies as less effective [Low Effective Copers]. High Effective Copers of both genders used Perspective Taking to a greater extent, and Depression and Calling Time Out to a lesser extent, than did Low Effective Copers. Recognition of Societal Influences, however, was more highly endorsed by female High Effective Copers than by male High Effective Copers or male and female Low Effective Copers. Also as hypothesized, females reported higher role conflict than males. Explanations based on the view that effective strategies differ with respect to the specific conflict situation being investigated and the characteristics of the respondants are considered. | [
"Management of Technology and Innovation",
"Strategy and Management",
"Arts and Humanities (miscellaneous)"
] | |
The environmental impacts and health hazards of abandoned boats in estuaries | [
"Animal Science and Zoology",
"Ecology",
"Aquatic Science",
"Ecology, Evolution, Behavior and Systematics"
] | ||
FRI0186 JOINT INVOLVEMENT AND DISEASE ACTIVITY IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS: CALCULATION OF SWOLLEN TO TENDER JOINT COUNT RATIO IN A REAL WORLD COHORT IN THE US | Background:Joint swelling and tenderness are common in patients with systemic lupus erythematosus (SLE). Swollen to tender joint count ratio (STR) is an index originally used in rheumatoid arthritis (RA) which assesses severity of disease activity based on 28 joint counts [1]. In RA, STR is a predictor of treatment response with a higher score indicating greater likelihood of responding.Objectives:To characterize SLE patients in a real-world cohort based on disease activity as defined by STR.Methods:The OM1 SLE Registry (OM1, Boston, MA) follows more than 37,000 SLE patients longitudinally with deep clinical data, including laboratory, patient-reported and disease activity information, and linked administrative claims, starting from 2013. Patients ≥16 years of age with swollen and tender joint counts based on 28 joints on the same encounter were included. STRs were calculated by inserting 1 if the denominator was 0 [2]. Patients were categorized by first available STR as having low (STR 1.0) disease activity. Clinical characteristics were summarized by disease activity group. Definitions of SLE treatments were based on 2019 EULAR recommendations [3].Results:As of December 2019, there were 9,919 patients with at least one STR available in the OM1 SLE Registry. STR was low in 80.4%, moderate in 12.2%, and high in 7.4% of patients. Mean age overall was 52.1 years (standard deviation: 14.8), 92.1% were female, and 71.8% of 7,730 patients with known race were white. Clinical characteristics by STR group are described in Table 1. Antimalarial use decreased and immunosuppressant use increased with increasing STR. Use of select disease-modifying antirheumatic drugs (DMARDs) was higher among patients with moderate or high STR. Lupus nephritis was more common in patients with low STR. A higher proportion of patients with moderate STR had osteoarthritis. The proportion of patients with anxiety and depression decreased with increasing STR. On average, patient and physician global assessments from MDHAQ were higher for patients with moderate STR.Table 1.Clinical characteristics of patients with SLE by swollen:tender joint count ratio groupLowSTR (N=7,970)Moderate0.5 ≤ STR ≤ 1.0(N=1,211)HighSTR >1.0(N=738)Treatment prior to STR, n (%) Antimalarial5,106 (64.1%)702 (58.0%)427 (57.9%) Biologics (belimumab or rituximab)662 (8.3%)113 (9.3%)70 (9.5%) Immunosuppressants2,310 (29.0%)398 (32.9%)252 (34.1%) Select DMARDs635 (8.0%)165 (13.6%)94 (12.7%) Steroids4,437 (55.7%)785 (64.8%)434 (58.8%)Disease conditions prior to STR, n (%) Anxiety266 (3.3%)25 (2.1%)12 (1.6%) Depression1,127 (14.1%)149 (12.3%)80 (10.8%) Lupus nephritis984 (12.3%)117 (9.7%)72 (9.8%) Osteoarthritis2,336 (29.3%)393 (32.5%)193 (26.2%) Osteoporosis631 (7.9%)95 (7.8%)47 (6.4%)MDHAQ, N1,991388230MDHAQ, mean (SD) Patient global assessment (0-10)4.5 (2.9)5.3 (2.7)4.4 (2.8) Physician global assessment (0-10)2.8 (2.7)3.8 (2.6)2.8 (2.3)Conclusion:Differences in treatments received were apparent between patients of varying disease activity groups with trends towards increased use among patients with higher disease activity. Additional research is needed to determine the utility of this measure for assessing SLE-related outcomes.References:[1]Cipriano et al., Reumatismo 2015 Sept 16;67(2):62-7[2]Hammer HB et al., Arthritis Rheumatol 2016; 68 (suppl 10)[3]Fanouriakis et al., Ann Rheum Dis. 2019;78:736-745Disclosure of Interests:None declared | [
"Immunology",
"Immunology and Allergy",
"Rheumatology"
] | |
Sexual Behaviors of Young Children That Occur in Schools | [
"Psychiatry and Mental Health"
] | ||
The Lost Indictment of Robert E. Lee: The Forgotten Case against an American Icon | Journal of American History | [
"History and Philosophy of Science",
"History"
] | |
Recent trends in Glaucoma management | [
"Ophthalmology"
] | ||
Conversion to everolimus in maintenance liver transplant patients: A multicenter, retrospective analysis | [
"Transplantation",
"Hepatology",
"Surgery"
] | ||
THE ORIGINS OF MEDIEVAL HERESY | [
"History"
] | ||
The Role Of Lactate In The Exercise-induced Growth Hormone Response | [
"Physical Therapy, Sports Therapy and Rehabilitation",
"Orthopedics and Sports Medicine"
] | ||
Studies directed toward the synthesis of viridenomycin. Route 1: assembly of three advanced intermediates | [
"Organic Chemistry",
"Drug Discovery",
"Biochemistry"
] | ||
The effect of platform characteristics on the adoption of smart speakers: Empirical evidence in South Korea | [
"Electrical and Electronic Engineering",
"Computer Networks and Communications"
] | ||
Leviathan after 350 Years (review) | [
"Philosophy"
] | ||
Ultrastructural evidence for the presence of ferritin-iron in the biliary system of patients with iron overload | [
"Hepatology"
] | ||
What determines the initiation of the heartbeat? | The Journal of Physiology | [
"Physiology"
] | |
Measurement of Length Shifts down to 10^−3 Å with a Two-Mode Laser | [
"Industrial and Manufacturing Engineering",
"Materials Science (miscellaneous)",
"Business and International Management"
] | ||
Relationship of mortality of aquatic biota from 96-hour sediment bioassays and the change in chemical composition of the test water | [
"Health, Toxicology and Mutagenesis",
"Pollution",
"Toxicology"
] | ||
Upregulation of the Netrin Receptor (DCC) Gene during Activation of B Lymphocytes and Modulation by Interleukins | [
"Cell Biology",
"Molecular Biology",
"Biochemistry",
"Biophysics"
] | ||
Racemization without deamidation: Effect of racemization conditions on 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate tagged amino acids | [
"Organic Chemistry",
"Biochemistry",
"Analytical Chemistry"
] | ||
Policy and Practice for Digital Archaeological Archiving in Italy | his article highlights how the Italian Central Institute for Archaeology (ICA) is developing the National Geoportal for Archaeology (GNA), based on the ARIADNEplus infrastructure and its policy framework. Thanks to the GNA project, it will be possible to search and learn about archaeological documentation managed by Superintendencies and Universities holding a significant amount of archaeological data, much of which is either completely or partially unpublished. | [
"Archeology"
] | |
BRIEF NOTICES | [
"Literature and Literary Theory",
"Linguistics and Language",
"Language and Linguistics"
] | ||
Shift and ratio method revisited: extraction of the fin width in multi-gate devices | [
"Materials Chemistry",
"Electrical and Electronic Engineering",
"Condensed Matter Physics",
"Electronic, Optical and Magnetic Materials"
] | ||
Zur Frage der Hellen Zellen der menschlichen Geb�rmutterschleimhaut | [
"Cell Biology",
"Molecular Biology",
"Pathology and Forensic Medicine"
] | ||
Web sites | Sensor Review | [
"Electrical and Electronic Engineering",
"Industrial and Manufacturing Engineering"
] | |
Transcriptional Regulation and Organization of the dcuA and dcuB Genes, Encoding Homologous Anaerobic C 4 -Dicarboxylate Transporters in Escherichia coli | ABSTRACT The dcuA and dcuB genes of Escherichia coli encode homologous proteins that appear to function as independent and mutually redundant C 4 -dicarboxylate transporters during anaerobiosis. The dcuA gene is 117 bp downstream of, and has the same polarity as, the aspartase gene ( aspA ), while dcuB is 77 bp upstream of, and has the same polarity as, the anaerobic fumarase gene ( fumB ). To learn more about the respective roles of the dcu genes, the environmental and regulatory factors influencing their expression were investigated by generating and analyzing single-copy dcuA - and dcuB-lacZ transcriptional fusions. The results show that dcuA is constitutively expressed whereas dcuB expression is highly regulated. The dcuB gene is strongly activated anaerobically by FNR, repressed in the presence of nitrate by NarL, and subject to cyclic AMP receptor protein (CRP)-mediated catabolite repression. In addition, dcuB is strongly induced by C 4 -dicarboxylates, suggesting that dcuB is under the control of an uncharacterized C 4 -dicarboxylate-responsive gene regulator. Northern blotting confirmed that dcuA (and aspA ) is expressed under both aerobic and anaerobic conditions and that dcuB (and fumB ) is induced anaerobically. Major monocistronic transcripts were identified for aspA and dcuA , as well as a minor species possibly corresponding to an aspA-dcuA cotranscript. Five major transcripts were observed for dcuB and fumB : monocistronic transcripts for both fumB and dcuB ; a dcuB-fumB cotranscript; and two transcripts, possibly corresponding to dcuB-fumB and fumB mRNA degradation products. Primer extension analysis revealed independent promoters for aspA , dcuA , and dcuB , but surprisingly no primer extension product could be detected for fumB . The expression of dcuB is entirely consistent with a primary role for DcuB in mediating C 4 -dicarboxylate transport during anaerobic fumarate respiration. The precise physiological purpose of DcuA remains unclear. | Journal of Bacteriology | [
"Molecular Biology",
"Microbiology"
] |
Performance of mesophytic species planted in the coast of Char Kashem, Pataukhali, Bangladesh | Mesophytic species such as Acacia nilotica, Albizia labeck, Albizia procera, Casuarina equisetifolia, Pithocellobium dulche, Samanea saman and Thespesia populnea were raised in the western coast of Char Kashem under Patuakhali district of Bangladesh. After seven years of planting highest survivability was found in A. labeck followed by P. dulche, C. equisetifolia, S. saman, A. procera, A. nilotica and T. populnea. The mean maximum diameter at breast height was found in S. saman followed by C. equisetifolia, A. procera, A. labeck, P. dulche, A. nilotica and T. populnea. The maximum plant height was found in C. equisetifolia followed by S. saman, A. procera, T. populnea, A. nilotica, A. labeck and P. dulche indicating suitability of all the seven species for plantation at Char Kashem. Key words: Mesophytes; Coastal afforestation; Growth performance; Bangladesh DOI: 10.3329/bjb.v39i2.7488 Bangladesh J. Bot. 39(2): 245-247, 2010 (December) | [
"Plant Science"
] | |
Sistotremastrum limonadense sp. nov. from French Guiana | A new species of Sistotremastrum J. Erikss. (Basidiomycota, Trechisporales) with (6-8)-spored basidia is described and supported by morphology and phylogenetic analyses based on ITS rDNA sequences. | [
"Plant Science",
"Ecology, Evolution, Behavior and Systematics"
] | |
Results of a Dose‐Finding Phase 1b Study of Subcutaneous Atezolizumab in Patients With Locally Advanced or Metastatic Non–Small Cell Lung Cancer | [
"Pharmacology (medical)",
"Pharmaceutical Science"
] | ||
THE WEB OF INTEREST: OUR FORESTS FOR RECREATION | [
"Forestry"
] | ||
Liquid chromatographic enantioseparation of ( RS )‐etodolac using ( S )‐levofloxacin and determination of absolute configuration of the diastereomeric derivatives | [
"Clinical Biochemistry",
"Drug Discovery",
"Pharmacology",
"Molecular Biology",
"Biochemistry",
"Analytical Chemistry"
] | ||
Monitoring Adherence Rate to Growth Hormone Therapy and Growth Outcomes in Taiwanese Children Using Easypod Connect: Observational Study | Background Adherence to growth hormone therapy is difficult to detect reliably. Devices such as easypod have been developed for electronic recording of injections. The easypod connect observational study (ECOS) was an open-label, observational, multinational, phase IV study conducted in 24 countries around the world. The final results from ECOS in the Taiwanese cohort are reported in this paper. Objective This study aimed to evaluate the adherence and long-term outcomes of growth hormone therapy in pediatric subjects using the easypod electromechanical device. Methods Subjects (aged 2-18 years or >18 years without fusion of growth plates) who received Saizen (recombinant human growth hormone, somatropin) via the easypod device were enrolled in this study. The primary objective was to assess the level of adherence in subjects receiving Saizen via easypod. Results In Taiwan, a total of 35 and 13 children fulfilled the criteria of full analysis set and complete analysis set, respectively. The mean (SD) age of the complete analysis set was 12.08 (2.72) years. All subjects were growth hormone–naïve, with 38% (5/13) females. The mean adherence rates of 13 subjects were 87.6% at 3 months and 84.3% at 6 months, that of 8 subjects was 81.0% at 9 months, and that of 4 subjects was 91.6% at 1 year. After 1 year of treatment, subjects had a median (Q1:Q3) change in height SD score of 0.30 (0.06:0.48), median height velocity of 6.50 (4.33:8.24) cm/year, and median change in height velocity SD score of 1.81 (–0.04:3.52). Conclusions With the easypod device, patients with inadequate adherence and poor response to treatment can be identified. Adherence to growth hormone therapy administered via easypod was generally high in the first year of treatment but the adherence gradually decreased over time. Overall, growth outcomes after 1 year indicated a positive growth response to growth hormone treatment. Future efforts should be focused on personalized management of adherence by using the easypod system. | [
"Computer Science Applications",
"Health Informatics",
"Biomedical Engineering",
"Pediatrics, Perinatology and Child Health"
] | |
Educação para a cidadania: questão colocada pelos movimentos sociais | O artigo problematiza a relação entre a cidadania e a educação das camadas populares. Tem por objetivo dialogar, no espaço e no tempo, com o conceito de cidadania, buscando averiguar se este possui conteúdo para infundir-se na educação das camadas populares e quais seus limites e possibilidades que precisam ficar claros para dar visibilidade e lugar a novos conceitos e práticas. Para alcançar tal objetivo os conceitos de cidadania e de educação são mergulhados na história e na filosofia, mais propriamente nas condições em que se assenta a constituição de um cidadão, deduzindo-se, a partir daí, a educação necessária a uma tal constituição. As contradições mostram as possibilidades e os limites da educação como via preferencial de acesso à cidadania, e o fato de que os movimentos sociais populares criam novas formas de produzir, de conviver e de se educar. Nesse processo, gestam novos conceitos cujos conteúdos, marcados pelas práticas de cooperação e solidariedade, parecem projetar a emancipação social em sentido mais amplo do que o proposto pelos princípios formais de liberdade e igualdade em que se assenta a cidadania burguesa. Assim, os movimentos sociais populares ampliam também o horizonte da educação para além da cidadania. | [
"Education"
] | |
A Microdischarge-Based Monolithic Pressure Sensor | Journal of Microelectromechanical Systems | [
"Electrical and Electronic Engineering",
"Mechanical Engineering"
] | |
Laser-Induced Photic Injury Phenocopies Macular Dystrophy | Ophthalmic Genetics | [
"Genetics (clinical)",
"Ophthalmology",
"Pediatrics, Perinatology and Child Health"
] | |
Streghe e folletti. Strategie divergenti nell'individuazione di poteri maligni | [
"Anthropology",
"Cultural Studies"
] | ||
The Ethical and Scientific Shortcomings of Current Monotherapy Epilepsy Trials in Newly Diagnosed Patients | Epilepsy & Behavior | [
"Behavioral Neuroscience",
"Neurology (clinical)",
"Neurology"
] | |
Evaluation of WHO Classification of Hypothermia in Sick Extramural Neonates as Predictor of Fatality | Journal of Tropical Pediatrics | [
"Infectious Diseases",
"Pediatrics, Perinatology and Child Health"
] | |
Errors in the Measurement of Machine Noise | The Journal of the Acoustical Society of America | [
"Acoustics and Ultrasonics",
"Arts and Humanities (miscellaneous)"
] | |
Pulmonary disease in liver transplant recipients: Spectrum of CT features | Purpose: To determine the features of pulmonary disease in liver transplant recipients by CT. Material and Methods: Of 792 patients, 102 were referred to thoracic CT 3-2093 days after the transplantation procedure (median 107 days). All CT studies were retrospectively analyzed and correlated with clinical, microbiological, serological and histopathological findings. Results: Eighty-eight of 102 patients (86%) had an abnormal CT. In 25 patients (25%), an elevated right hemidiaphragm, basal atelectasis and small effusions were the only abnormalities. Fourty-one patients (40%) displayed an infiltrate and 13 (13%) a mass lesion. Evidence of cytomegalovirus (CMV) infection was found in 20 patients. CMV pneumonia was suggested by an interstitial pattern of pneumonia on CT (n=13). Pneumocystis carinii pneumonia was highlighted by peribronchovascular infiltrates (n=5/8), bacterial pneumonia (n=24) including legionellosis (n=13) by bilateral effusions (n=14) and lobar consolidation (n=13). In 7/41 patients (17%) with both clinically apparent pulmonary disease and CT signs of pneumonia, no pathogen could be detected. Neoplastic disease was mostly due to tumor recurrence (n=6). Conclusion: Thoracic CT of liver transplant recipients aids in detecting and classifying both infectious and neoplastic complications. | [
"Radiology, Nuclear Medicine and Imaging",
"Radiological and Ultrasound Technology"
] | |
Input-Orientated Data Envelopment Analysis Framework for Measuring and Decomposing Economic, Environmental and Ecological Efficiency: An Application to OECD Agriculture | [
"Management, Monitoring, Policy and Law",
"Economics and Econometrics"
] | ||
Une campagne de fouilles au Djebel-el-Chaar en 1934 | [
"Archeology",
"History"
] | ||
Reactive Navigation of an Unmanned Aerial Vehicle With Perception-Based Obstacle Avoidance Constraints | IEEE Transactions on Control Systems Technology | [
"Electrical and Electronic Engineering",
"Control and Systems Engineering"
] | |
Serum periostin levels in acute rheumatic fever: is it useful as a new biomarker? | [
"Pediatrics, Perinatology and Child Health"
] | ||
Mitral-Semilunar Valve Relationships in the Angiography of Cardiac Malformations | [
"Radiology, Nuclear Medicine and Imaging"
] | ||
Endocrinology & Metabolism News | [
"Biochemistry (medical)",
"Clinical Biochemistry",
"Endocrinology",
"Biochemistry",
"Endocrinology, Diabetes and Metabolism"
] | ||
Significance of the antiangiogenic mechanisms of thalidomide in the therapy of diabetic retinopathy | Vascular Pharmacology | [
"Pharmacology",
"Molecular Medicine",
"Physiology"
] | |
Hemophilic Pseudotumor of the Temporal Bone With Conductive Hearing Loss | Neurologia medico-chirurgica | [
"Neurology (clinical)",
"Surgery"
] | |
Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the α-synuclein (SNCA) gene associated with Parkinson’s disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007) | Stem Cell Research | [
"Cell Biology",
"Developmental Biology"
] | |
Lautheitseinflu� auf die Informationsverarbeitung beim binauralen H�ren des Menschen | [
"Physiology (medical)",
"Clinical Biochemistry",
"Physiology"
] | ||
Emigration and Collective Action | [
"Sociology and Political Science"
] | ||
Ritual uses of palms in traditional medicine in sub-Saharan Africa: a review | [
"Complementary and Alternative Medicine",
"Cultural Studies",
"Health (social science)"
] | ||
Cathodes for operation in a high-voltage glow discharge | [
"Materials Chemistry",
"Metals and Alloys",
"Mechanics of Materials",
"Condensed Matter Physics",
"Ceramics and Composites"
] | ||
High-Density Lipoproteins in Untreated Idiopathic Nephrotic Syndrome Without Renal Failure | [
"Transplantation",
"Nephrology"
] | ||
Minimally invasive transforaminal lumbar interbody fusion — A narrative review on the present status | Journal of Clinical Orthopaedics and Trauma | [
"Orthopedics and Sports Medicine"
] |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.