di-zhang-fdu/orderly_qa_pt · Datasets at Hugging Face

problem stringlengths 74 795
Using Fc1ccc(-c2nn3c(c2-c2ccncc2)NNCC3)cc1 and O=C(O)Cc1c[nH]c2ccccc12 to produce O=C(Cc1c[nH]c2ccccc12)N1CCn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c2N1, the solvents is CN(C)C=O and O, the agents is CCN=C=NCCCN(C)C and On1nnc2ccccc21
Using CCc1nc2cnc3cc(OCc4ccccc4)ccc3c2n1CC1CCOCC1 to produce CCc1nc2cnc3cc(O)ccc3c2n1CC1CCOCC1, the solvents is CC#N and CO, the agents is [Pd]
Using COC(=O)c1ccc(Oc2ccccc2[N+](=O)[O-])cc1C(=O)OC to produce COC(=O)c1ccc(Oc2ccccc2N)cc1C(=O)OC, the solvents is ClCCl, the agents is [Pd]
Using O=C(O)C(F)(F)C(F)Br and CC(C)Oc1ccc(-c2nc(-c3ccc4[nH]ccc4c3)no2)cc1Cl to produce CC(C)Oc1ccc(-c2nc(-c3ccc4c(ccn4C(F)C(F)(F)C(=O)O)c3)no2)cc1Cl, the solvents is CN(C)C=O, the agents is O=C([O-])[O-] and [Cs+]
Using O=Cc1c(O)cccc1F and CC(C)I to produce CC(C)Oc1cccc(F)c1C=O, the solvents is CN(C)C=O and CCOCC, the agents is O=C([O-])[O-] and [K+] and [Cs+]
Using C[O-] and CCCCCNc1nc(N)c2nc(Br)n(C3CCCCO3)c2n1 to produce CCCCCNc1nc(N)c2nc(OC)n(C3CCCCO3)c2n1, the solvents is CO, the agents is [Na+]
Using Brc1ccc2c(c1)OCC2 and CN(C)C=O to produce O=Cc1ccc2c(c1)OCC2, the solvents is C1CCOC1, the agents is [Li]CCCC
Using CCOC(=O)CNC(=O)CCc1c[nH]c2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc12 to produce CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCC(=O)NCC(=O)O)c[nH]c34)no2)cc1Cl, the solvents is C1CCOC1, the agents is [Na+] and Cl and [OH-]
Using CCOC(=O)c1sc(NC(=O)OC(C)(C)C)nc1C to produce Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)O, the solvents is CO, the agents is [Na+] and [OH-]
Using O=C(Cc1ccc(F)cc1)N1CC(N2CCOCC2)CN1C(=O)c1ccnc(Oc2ccccc2)n1 to produce O=c1c(-c2ccc(F)cc2)c(-c2ccnc(Oc3ccccc3)n2)n2n1CC(N1CCOCC1)C2, the solvents is CN(C)C=O, the agents is [Na+] and [H-]
Using O=C1CCc2nc3cc(C#Cc4cccc(F)c4)ccc3c(=O)n2C1 to produce O=c1c2ccc(C#Cc3cccc(F)c3)cc2nc2n1CC(O)CC2, the solvents is C1CCOC1, the agents is [Na+] and [BH4-]
Using O=C1CCC(=O)N1Br and Cc1ccc(F)c(C(C)(C)C)c1 to produce CC(C)(C)c1cc(CBr)ccc1F, the solvents is ClC(Cl)(Cl)Cl, the agents is O=C(OOC(=O)c1ccccc1)c1ccccc1
Using O=C(O)c1ccccc1F and O=[N+]([O-])c1cnc(OC2CCNCC2)c2ccccc12 to produce O=C(c1ccccc1F)N1CCC(Oc2ncc([N+](=O)[O-])c3ccccc23)CC1, the solvents is C1CCOC1, the agents is On1nnc2ccccc21 and C(=NC1CCCCC1)=NC1CCCCC1
Using C=CCCC=C and C[SiH](C)Cl to produce CCCCC=C[Si](C)(C)Cl, the solvents is Cc1ccccc1C, the agents is [Pt]
Using CCCOc1ccc(Br)cc1CNCC and N#Cc1ccc(Cl)nn1 to produce CCCOc1ccc(Br)cc1CN(CC)c1ccc(C#N)nn1, the solvents is CCOC(C)=O and CN1CCCC1=O, the agents is [Na+] and Cl and O=C([O-])O
Using CC(C)(C)OC(=O)N[C@@H](Cc1ccncc1)C(=O)O and CCN(C(C)C)C(C)C to produce CC(C)(C)OC(=O)N[C@H](Cc1ccncc1)C(=O)N1CCCC1, the solvents is C1CCNC1 and ClCCl, the agents is CC(C)COC(=O)Cl
Using O=C(O)c1cccc(CCl)c1 and C=CCCOCc1ccc(C(=O)O)cc1 to produce CCCOCc1cccc(C(=O)O)c1, the solvents is CCCO, the agents is [Na+] and [H-]
Using CCOC(=O)COC1C2OC3(OCC45CC6C(C)CCC6C6(C=O)CC4C=C(C(C)C)C65C(=O)OC(c4ccccc4)c4ccccc4)OC2OC1C3O to produce CCOC(=O)COC1C2OC3(OCC45CC6C(C)CCC6C6(C=O)CC4C=C(C(C)C)C65C(=O)O)OC2OC1C3O, the solvents is CCOC(C)=O, the agents is [C] and [Pd]
Using O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CBr)CS[C@H]12 and O=C([O-])CCCO to produce O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)C(COC(=O)CCCO)=CS[C@H]12, the solvents is CCOC(C)=O and CN(C)P(=O)(N(C)C)N(C)C, the agents is [Na+]
Using O=C(Cl)OCC(Cl)(Cl)Cl and Cc1ccc(-n2nc(C(C)(C)C)cc2N)cc1 to produce Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1, the solvents is CCOC(C)=O and O, the agents is [Na+] and Cl and [OH-]
Using CCOC(=O)c1c(C)nc(N2CCc3ccccc3C2)nc1C to produce Cc1nc(N2CCc3ccccc3C2)nc(C)c1C(=O)O, the solvents is CCO and O, the agents is [Na+] and [OH-]
Using CC(C)(C)OC(=O)N1CCC(C=O)CC1 and CCCNC1CCc2ccc(O)cc2C1 to produce CCCN(CC1CCN(C(=O)OC(C)(C)C)CC1)C1CCc2ccc(O)cc2C1, the solvents is CC(Cl)Cl, the agents is CC(=O)O[BH-](OC(C)=O)OC(C)=O and [Na+]
Using C=CCO[C@H]1Cc2ccc(OC)cc2[C@H]1NC(=O)C(F)(F)F to produce C=CCO[C@H]1Cc2ccc(OC)cc2[C@H]1N, the solvents is CO, the agents is O=C([O-])[O-] and [K+]
Using CN(C)C=O and Cc1ccn(-c2cccc(F)c2)n1 to produce Cc1nn(-c2cccc(F)c2)cc1C=O, the solvents is O=P(Cl)(Cl)Cl, the agents is [Na+] and O=C([O-])O
Using N[C@@H](CS)C(=O)O and COC(=O)SCCCN1C(=O)NCC1c1ccccc1 to produce N[C@@H](CSSCCCN1C(=O)NCC1c1ccccc1)C(=O)O, the solvents is O and CO, the agents is Cl
Using Cc1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1 and CC1=C(C)C(C)([Ti](Cl)(Cl)Cl)C(C)=C1C to produce CC1=C(C)C(C)([Ti](Cl)(Cl)Oc2c(-c3ccccc3)cc(C)cc2-c2ccccc2)C(C)=C1C, the solvents is Cc1ccccc1, the agents is [Na+] and [H-]
Using CC(C)(C)OC(=O)N[C@H]1CC[C@H](C=CS(C)(=O)=O)CC1 to produce CC(C)(C)OC(=O)N[C@H]1CC[C@H](CCS(C)(=O)=O)CC1, the solvents is CO, the agents is [Pd]
Using Sc1nc2ccccc2[nH]1 and O=C(CBr)c1ccccc1 to produce O=C(CSc1nc2ccccc2[nH]1)c1ccccc1, the solvents is CO, the agents is [Na+] and [OH-]
Using CCCC[Sn](CCCC)(CCCC)c1cncs1 and CS(=O)(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1 to produce CS(=O)(=O)N1CCN(Cc2cc3nc(-c4cncs4)nc(N4CCOCC4)c3s2)CC1, the solvents is CC(=O)N(C)C, the agents is c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1
Using [NH4+] and CCOC(=O)c1cn([C@@H](CSc2cccc3ccccc23)[C@H](C)O)cn1 to produce C[C@H](O)[C@H](CSc1cccc2ccccc12)n1cnc(C(N)=O)c1, the solvents is COCCOC, the agents is [OH-]
Using O=Cc1ccc(C(F)(F)F)cc1 and COC(=O)c1ccc(I)cc1 to produce COC(=O)c1ccc(C(O)c2ccc(C(F)(F)F)cc2)cc1, the solvents is C1CCOC1, the agents is CC(C)[Mg]Cl and N#N
Using O=C=O and COc1c(Br)ccc2[nH]nc(-c3cccc(F)c3)c12 to produce COc1c(C(=O)O)ccc2[nH]nc(-c3cccc(F)c3)c12, the solvents is CCCCCC and C1CCOC1, the agents is [Cl-] and [NH4+] and [Li]CCCC
Using FCCBr and Clc1ncnc2cc[nH]c12 to produce FCCn1ccc2ncnc(Cl)c21, the solvents is CN(C)C=O and O, the agents is O=C([O-])[O-] and [Cs+]
Using C[Si](C)(C)OC1=CC(c2ccc(Cl)nc2)CC1 to produce O=C1CCC(c2ccc(Cl)nc2)C1, the solvents is CCOC(C)=O and C1CCOC1, the agents is [Na+] and Cl and O=C([O-])O
Using C#CCOc1ccc(C[C@H](N)C(=O)O)cc1 and NC(Cc1ccccc1)C(=O)O to produce C#CCOC(=O)C(N)Cc1ccc(OCC#C)cc1, the solvents is O and CO, the agents is [Na+] and Cl and [OH-]
Using CCOC(=O)CC[C@@H](NC(=O)CCC(NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C)C(=O)OCC to produce CCOC(=O)CC[C@@H](NC(=O)CCC(N)C(=O)OC(C)(C)C)C(=O)OCC, the solvents is CCO, the agents is [Pd]
Using CC(C)n1nc(CN=[N+]=[N-])c(Cc2ccncc2)c1Sc1cc(Cl)cc(Cl)c1 to produce CC(C)n1nc(CN)c(Cc2ccncc2)c1Sc1cc(Cl)cc(Cl)c1, the solvents is CCOC(C)=O, the agents is [Pd]
Using O=[N+]([O-])c1ccc(F)c(F)c1F and CCOC(=O)CC(C)=O to produce CC(=O)Cc1c([N+](=O)[O-])ccc(F)c1F, the solvents is C1CCOC1, the agents is [Na+] and [H-]
Using O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1 and OCc1nc2cccnc2n1Cc1ccc(-c2ccccc2)cc1 to produce O=C1SC(Cc2ccc(OCc3nc4cccnc4n3Cc3ccc(-c4ccccc4)cc3)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1, the solvents is c1ccccc1, the agents is CCCCP(CCCC)CCCC and O=C(N=NC(=O)N1CCCCC1)N1CCCCC1
Using CC(=O)CCC(C)=O and Nc1ccc(Br)cn1 to produce Cc1ccc(C)n1-c1ccc(Br)cn1, the solvents is CC(=O)O and C1CCCCC1, the agents is C
Using COc1cc(N)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1 and O=C(Cl)OCCCl to produce COc1cc(N2CCOC2=O)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1, the solvents is C1CCOC1 and CCN(CC)CC, the agents is [Na+] and O=C([O-])O
Using COc1ccc(CC(Cc2ccc(OC)cc2)N2C(=O)[C@H]([C@@H](C)OC(=O)OCc3ccccc3)[C@H]2[C@@H](C)CO[Si](C)(C)C(C)(C)C)cc1 to produce COc1ccc(CC(Cc2ccc(OC)cc2)N2C(=O)[C@H]([C@@H](C)OC(=O)OCc3ccccc3)[C@H]2[C@@H](C)CO)cc1, the solvents is CCOC(C)=O and CO, the agents is Cl
Using Cc1cc(Cl)ccc1OCC(=O)O to produce Cc1cc(Cl)ccc1OCC(=O)[O-], the solvents is CO, the agents is [K+] and [OH-]
Using CCOCNc1ncccc1C(=O)NCc1ccc(Oc2ccccc2)s1 to produce CNc1ncccc1C(=O)NCc1ccc(Oc2ccccc2)s1, the solvents is O and CS(C)=O, the agents is [Na+] and [BH4-]
Using CCOC(=O)c1ccc(F)c(NS(=O)(=O)c2c(F)cccc2F)c1 and Cc1ccnc(Cl)n1 to produce O=C(Cc1ccnc(Cl)n1)c1ccc(F)c(NS(=O)(=O)c2c(F)cccc2F)c1, the solvents is C1CCOC1, the agents is C[Si](C)(C)[N-][Si](C)(C)C and [Li+]
Using OCC(Cl)(Cl)Cl and CCOC(Cc1ccc(C(C)(C)O[SiH2]C(C)(C)C)cc1)C(=O)O to produce CCOC(Cc1ccc(C(C)(C)O[SiH2]C(C)(C)C)cc1)C(=O)OCC(Cl)(Cl)Cl, the solvents is ClCCl and ClCCCl, the agents is CN(C)c1ccncc1 and Cl
Using CN1CCC(OC(c2cccc(C=O)c2)c2nc3ccccc3[nH]2)CC1 to produce CN1CCC(OC(c2cccc(CO)c2)c2nc3ccccc3[nH]2)CC1, the solvents is CO, the agents is [Na+] and [BH4-]
Using CCOC(=O)C1=NCc2c(c3ccccc3n2S(=O)(=O)c2ccc(C)cc2)N1 to produce O=C(O)c1ncc2[nH]c3ccccc3c2n1, the solvents is Cc1ccccc1C, the agents is [C] and [Pd]
Using CN1CCN(c2cc(CS(=O)(=O)c3cccc4ccccc34)c([N+](=O)[O-])c(OCCCl)c2)CC1 to produce CN1CCN(c2cc(CS(=O)(=O)c3cccc4ccccc34)c(N)c(OCCCl)c2)CC1, the solvents is C1CCOC1 and CO, the agents is [Pd]
Using ClCC1CO1 and CC(=O)N1CCc2[nH]nc(-c3ccc(Br)cc3)c2C1 to produce CC(=O)N1CCc2c(c(-c3ccc(Br)cc3)nn2CC2CO2)C1, the solvents is CCOC(C)=O and CN(C)C=O, the agents is O=C([O-])[O-] and [Cs+]
Using CC(C)OC(=O)[C@@H](O)[C@@H](Cc1ccccc1)C(=O)OC(C)C to produce O=C(O)[C@@H](O)[C@@H](Cc1ccccc1)C(=O)O, the solvents is O and C1CCOC1, the agents is [K+] and [OH-]
Using Cc1ccc(S(=O)(=O)OC[C@H]2CCCN2C(=O)OC(C)(C)C)cc1 and Oc1ccc(OCc2ccccc2)cc1 to produce CC(C)(C)OC(=O)N1CCCC1COc1ccc(OCc2ccccc2)cc1, the solvents is CN(C)C=O, the agents is [Na+] and [H-]
Using CS(=O)(=O)Cl and O=S(=O)([O-])c1ccc(O)cc1 to produce CS(=O)(=O)Oc1ccc(S(=O)(=O)[O-])cc1, the solvents is O, the agents is [Cl-] and [Na+] and [OH-]
Using CC(CO)N1CCNCC1 and COc1cc(CCc2cc(NC(=O)c3ccc(F)cc3)[nH]n2)cc(OC)c1 to produce COc1cc(CCc2cc(NC(=O)c3ccc(N4CCN(C(C)CO)CC4)cc3)[nH]n2)cc(OC)c1, the solvents is CS(C)=O and CCN(C(C)C)C(C)C, the agents is Cl
Using CCOC(=O)c1cn(-c2cc(NC(=O)OC(C)(C)C)c(F)cc2F)c2c(Cl)c(F)c(F)cc2c1=O and [N-]=[N+]=[N-] to produce CCOC(=O)c1cn(-c2cc(NC(=O)OC(C)(C)C)c(F)cc2F)c2c(Cl)c(N=[N+]=[N-])c(F)cc2c1=O, the solvents is CCOC(C)=O and CN(C)C=O, the agents is [Na+]
Using Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1C(=O)CSC(c1ccccc1)(c1ccccc1)c1ccccc1 to produce Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1C(=O)CS, the solvents is O=C(O)C(F)(F)F and ClCCl, the agents is CC[SiH](CC)CC
Using Sc1nc2ccc(Cl)nc2s1 and C1CCOC1 to produce CSc1nc2ccc(Cl)nc2s1, the solvents is CCOC(C)=O and CI, the agents is O=C([O-])[O-] and [K+]
Using COC(=O)CCC(=O)c1ccc(OC)c(OC)c1OC to produce COc1ccc(C(=O)CCC(=O)O)c(OC)c1OC, the solvents is O and CO, the agents is [Na+] and [OH-]
Using O=C(N=C=S)c1ccccc1 and COc1cc(N)ccc1Cl to produce COc1cc(NC(N)=S)ccc1Cl, the solvents is O and C1CCOC1, the agents is O=C([O-])[O-] and [K+]
Using CC(C)(C)OC(=O)Nc1ccc2c(c1)C(=O)N[C@H](C(=O)O)C2 and NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c[nH]cn1 to produce CC(C)(C)OC(=O)Nc1ccc2c(c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(N)=O)C2, the solvents is CN(C)C=O and CCN(CC)CC, the agents is O=C1CCC(=O)N1O and C(=NC1CCCCC1)=NC1CCCCC1
Using COC(=O)c1cc(Cl)cc(NC2CCOCC2)c1C and O=C([O-])[O-] to produce COC(=O)c1cc(Cl)cc(N(C)C2CCOCC2)c1C, the solvents is CC#N and CI, the agents is [Cs+]
Using [Cl-] and O=C(O)CC12CC3CC(CC(C3)C1)C2 to produce O=C(O)CC12CC3CC(CC(Cl)(C3)C1)C2, the solvents is ClC(Cl)(Cl)Cl and CC(C)(C)O, the agents is O=S(=O)(O)O and [Na+]
Using Nc1ccn2nc(N3CCCC3)nc2c1 and CCOC(=O)c1cnn(C)c1C(=O)O to produce CCOC(=O)c1cnn(C)c1C(=O)Nc1ccn2nc(N3CCCC3)nc2c1, the solvents is C1CCOC1 and CCN(C(C)C)C(C)C, the agents is CCCP(=O)=O
Using O=C1CCN2CCCC2C1 and NNc1cccc(Br)c1 to produce Brc1ccc2c3c([nH]c2c1)CC1CCCN1C3, the solvents is CCO, the agents is Cl
Using BrCc1ccc(Br)cc1 and C=CCCBr to produce C=CCCCc1ccc(Br)cc1, the solvents is C1CCOC1, the agents is [Mg] and Cl
Using COC(=O)c1cnc2snnc2c1 to produce O=C(O)c1cnc2snnc2c1, the solvents is C1CCOC1, the agents is [Na+] and [OH-]
Using CCCCCNC(=O)N(C)c1cccc(-c2cnc(C=CC(=O)[O-])nc2)c1 to produce CCCCCNC(=O)N(C)c1cccc(-c2cnc(C=CC(=O)O)nc2)c1, the solvents is O and C1CCOC1, the agents is [Na+] and [OH-]
Using COC(=O)c1c2ccccc2[n+](C)c2ccc(Cl)cc12 to produce COC(=O)C1c2ccccc2N(C)c2ccc(Cl)cc21, the solvents is O and CO, the agents is [K+] and [BH4-] and O=S(=O)([O-])[O-]
Using CC(C)n1c(C=O)c(-c2ccc(F)cc2)c2ccccc21 and CCOP(=O)(CC(=O)N(C)OC)OCC to produce CON(C)C(=O)/C=C/c1c(-c2ccc(F)cc2)c2ccccc2n1C(C)C, the solvents is O and C1CCOC1, the agents is [Na+] and [H-]
Using On1nnc2ccccc21 and CCC1c2sc(C(=O)O)nc2CCN1/C(=N/c1ccccc1)SC to produce CSC(=Nc1ccccc1)N1CCc2nc(C(=O)Nc3ccccc3N)sc2C1, the solvents is CN(C)C=O and CCN(CC)CC, the agents is CCN=C=NCCCN(C)C
Using NC(=O)CCl and CC(C)(C)OC(=O)N1CCN(c2ccc(O)c(C=O)c2)CC1 to produce CC(C)(C)OC(=O)N1CCN(c2ccc3oc(C(N)=O)cc3c2)CC1, the solvents is CN1CCCC1=O, the agents is O=C([O-])[O-] and [K+]
Using COc1ccc2cc(Oc3ccc([N+](=O)[O-])cc3)ccc2c1 to produce COc1ccc2cc(Oc3ccc(N)cc3)ccc2c1, the solvents is CCOC(C)=O, the agents is [Pd]
Using CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)cc(OCc3ccccc3)c3ccccc32)CC1 to produce CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)cc(O)c3ccccc32)CC1, the solvents is C1CCOC1 and CO, the agents is [Pd]
Using CCOC(=O)C(Cc1cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(C)c1)C(O)([PH2]=O)C(NC(=O)OCc1ccccc1)C(C)C to produce Cc1cc(CC(C(=O)O)C(O)([PH2]=O)C(NC(=O)OCc2ccccc2)C(C)C)cnc1NC(=O)OC(C)(C)C, the solvents is CC#N and CO, the agents is [Li+] and [OH-]
Using CC(C)(C)CCI and CC(C(=O)O)c1ccccc1 to produce CC(C)(C)CCC(C)(C(=O)O)c1ccccc1, the solvents is C1CCOC1, the agents is C[Si](C)(C)[N-][Si](C)(C)C and [Li+]
Using COc1ccc(C)c(N)c1 and O=C(Cl)CCl to produce COc1ccc(C)c(NC(=O)CCl)c1, the solvents is C1CCOC1 and CCN(C(C)C)C(C)C, the agents is Cl
Using [N-]=[N+]=Nc1ccc(Cl)cc1C(=O)c1ccccc1 and NO to produce [N-]=[N+]=Nc1ccc(Cl)cc1C(=NO)c1ccccc1, the solvents is CCO and c1ccncc1, the agents is Cl
Using CCC(C)=O and CC1(C)C(CC=O)CC2CC21C to produce CC(=O)C(C)=CCC1CC2CC2(C)C1(C)C, the solvents is O and CO, the agents is [K+] and [OH-]
Using Brc1ccc(Br)nc1 and OB(O)c1ccc(OCc2ccccc2)c(F)c1 to produce Fc1cc(-c2ccc(Br)cn2)ccc1OCc1ccccc1, the solvents is CCO and Cc1ccccc1, the agents is O=C([O-])[O-] and [Na+] and c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1
Using COC(=O)C1=C(NC2CC2)OC(=Cc2c[nH]c3ncccc23)C1=O to produce O=C1C=C(NC2CC2)OC1=Cc1c[nH]c2ncccc12, the solvents is CCO, the agents is [K+] and [OH-]
Using NO and O=C(O)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)cc1 to produce O=C(O)C(=NO)c1ccc(OCCOc2ccc3ccccc3c2)cc1, the solvents is CN(C)C=O, the agents is [Na+] and Cl and [OH-]
Using CCOC(=O)CBr and O=c1[nH]c2ccccc2c(=O)n1Cc1ccc(Cl)c(Cl)c1 to produce CCOC(=O)Cn1c(=O)n(Cc2ccc(Cl)c(Cl)c2)c(=O)c2ccccc21, the solvents is CN(C)C=O, the agents is [Na+] and Cl and [H-]
Using CC(C)c1cc(Oc2c(Br)cc([N+](=O)[O-])c(C(F)(F)F)c2Br)cc(C=O)c1O to produce Cc1cc(Oc2c(Br)cc([N+](=O)[O-])c(C(F)(F)F)c2Br)cc(C(C)C)c1O, the solvents is O=C(O)C(F)(F)F, the agents is CC[SiH](CC)CC
Using O=C1C=CC(=O)C=C1 and CCOC(=O)C[Zn]Br to produce CCOC(=O)CC1(O)C=CC(=O)C=C1, the solvents is CCOC(C)=O and C1CCOC1, the agents is Cl
Using CN(C)C=NS(=O)(=O)c1ccc(Br)s1 and OCC(O)CS to produce NS(=O)(=O)c1ccc(SCC(O)CO)s1, the solvents is CN(C)C=O and O, the agents is [Na+] and [H-]
Using O=Cc1cc2cnccc2o1 to produce OCc1cc2cnccc2o1, the solvents is CO, the agents is [Na+] and [BH4-]
Using Nc1ccc(CC(O)c2ccccc2C(=O)O)cc1 to produce O=C(O)c1ccccc1C(O)Cc1ccc(N(Cc2ccccc2)Cc2ccccc2)cc1, the solvents is CO, the agents is [Pd]
Using CC(C)(C)OC(=O)NC1(C#Cc2ccc(OCCC3=CCC4CC3C4(C)C)cc2)COC(C)(C)OC1 to produce CC(C)(C)OC(=O)NC1(CCc2ccc(OCCC3=CCC4CC3C4(C)C)cc2)COC(C)(C)OC1, the solvents is CCO, the agents is [Pd]
Using CCOC(=O)CCn1nc(-c2cccnc2)c(C#N)c1N to produce N#Cc1c(-c2cccnc2)nn2c1NC(=O)CC2, the solvents is O and C1CCOC1, the agents is [Li]CCCC
Using c1cnc2ccc(Cn3nnc4cnc(-c5cnn(CCOC6CCCCO6)c5)nc43)cc2c1 to produce OCCn1cc(-c2ncc3nnn(Cc4ccc5ncccc5c4)c3n2)cn1, the solvents is O and CO, the agents is Cc1ccc(S(=O)(=O)O)cc1
Using O=C1CCN(c2ccccc2)c2ccccc21 and CCOC(=O)OCC to produce CCOC(=O)C1=C(O)c2ccccc2N(c2ccccc2)C1, the solvents is c1ccccc1, the agents is [Na+] and [H-]
Using CC(=O)NNC(C)=O and ClCCOCCCl to produce CC(=O)n1ccoccn1C(C)=O, the solvents is CC(C)O and CS(C)=O, the agents is O=C([O-])[O-] and [K+] and [OH-]
Using COc1cc(C(=O)OC(C)(C)C)ccc1CBr and COc1cc(C(=O)NS(=O)(=O)c2ccccc2)ccc1Cn1cc(CCC(=O)N2CCOCC2)c2ccc(C(=O)NCC3CCCC3)cc21 to produce COc1cc(C(=O)O)ccc1Cn1cc(CCC(=O)N2CCOCC2)c2ccc(C(=O)NCC3CCCC3)cc21, the solvents is O and C1COCCN1, the agents is CN(C)c1ccncc1 and Cl
Using C[Si](C)(C)N1CCCC1=O and c1ccc2c(c1)OCCC1OC21 to produce O=C1CCCN1[C@@H]1c2ccccc2OCC[C@H]1O, the solvents is O and C1CCOC1, the agents is [F-] and CCCC[N+](CCCC)(CCCC)CCCC
Using COc1cccc2cc(CNCCNC(=O)C34CC5CC(CC(C5)C3)C4)oc12 to produce COc1cccc2cc(CN(C)CCNC(=O)C34CC5CC(CC(C5)C3)C4)oc12, the solvents is CCO and O, the agents is Cl and C=O and [Pd]
Using CI and CCOC(=O)Cc1cccc(OCOC)c1 to produce CCOC(=O)C(C)c1cccc(OCOC)c1, the solvents is CN(C)C=O, the agents is [Na+] and [H-]
Using N#Cc1cc(C(F)(F)F)ccc1F and Nc1ccccc1[N+](=O)[O-] to produce N#Cc1cc(C(F)(F)F)ccc1Nc1ccccc1[N+](=O)[O-], the solvents is CN(C)C=O, the agents is O=C([O-])[O-] and [Cs+] and Cl
Using CCn1nc(C(N)=O)cc1CCS(C)(=O)=O to produce CCn1nc(C#N)cc1CCS(C)(=O)=O, the solvents is O=P(Cl)(Cl)Cl, the agents is [NH4+] and [OH-]
Using CC(=O)OCC1(COC(C)=O)Sc2cc3c(cc2S1)SC(COC(C)=O)(COC(C)=O)S3 to produce OCC1(CO)Sc2cc3c(cc2S1)SC(CO)(CO)S3, the solvents is CO, the agents is O=C([O-])[O-] and [K+]
Using COc1cc(Cn2c3ccccc3c3c(OC(C)(C)C(=O)O)cccc32)ccc1OCc1nc(-c2ccccc2)oc1C to produce COc1cc(Cn2c3ccccc3c3c(OC(C)(C)C(=O)[O-])cccc32)ccc1OCc1nc(-c2ccccc2)oc1C, the solvents is CC(C)O, the agents is [Na+] and [OH-]

Using Fc1ccc(-c2nn3c(c2-c2ccncc2)NNCC3)cc1 and O=C(O)Cc1c[nH]c2ccccc12 to produce O=C(Cc1c[nH]c2ccccc12)N1CCn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c2N1, the solvents is CN(C)C=O and O, the agents is CCN=C=NCCCN(C)C and On1nnc2ccccc21

Using CCc1nc2cnc3cc(OCc4ccccc4)ccc3c2n1CC1CCOCC1 to produce CCc1nc2cnc3cc(O)ccc3c2n1CC1CCOCC1, the solvents is CC#N and CO, the agents is [Pd]

Using COC(=O)c1ccc(Oc2ccccc2[N+](=O)[O-])cc1C(=O)OC to produce COC(=O)c1ccc(Oc2ccccc2N)cc1C(=O)OC, the solvents is ClCCl, the agents is [Pd]

Using O=C(O)C(F)(F)C(F)Br and CC(C)Oc1ccc(-c2nc(-c3ccc4[nH]ccc4c3)no2)cc1Cl to produce CC(C)Oc1ccc(-c2nc(-c3ccc4c(ccn4C(F)C(F)(F)C(=O)O)c3)no2)cc1Cl, the solvents is CN(C)C=O, the agents is O=C([O-])[O-] and [Cs+]

Using O=Cc1c(O)cccc1F and CC(C)I to produce CC(C)Oc1cccc(F)c1C=O, the solvents is CN(C)C=O and CCOCC, the agents is O=C([O-])[O-] and [K+] and [Cs+]

Using C[O-] and CCCCCNc1nc(N)c2nc(Br)n(C3CCCCO3)c2n1 to produce CCCCCNc1nc(N)c2nc(OC)n(C3CCCCO3)c2n1, the solvents is CO, the agents is [Na+]

Using Brc1ccc2c(c1)OCC2 and CN(C)C=O to produce O=Cc1ccc2c(c1)OCC2, the solvents is C1CCOC1, the agents is [Li]CCCC

Using CCOC(=O)CNC(=O)CCc1c[nH]c2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc12 to produce CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCC(=O)NCC(=O)O)c[nH]c34)no2)cc1Cl, the solvents is C1CCOC1, the agents is [Na+] and Cl and [OH-]

Using CCOC(=O)c1sc(NC(=O)OC(C)(C)C)nc1C to produce Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)O, the solvents is CO, the agents is [Na+] and [OH-]

Using O=C(Cc1ccc(F)cc1)N1CC(N2CCOCC2)CN1C(=O)c1ccnc(Oc2ccccc2)n1 to produce O=c1c(-c2ccc(F)cc2)c(-c2ccnc(Oc3ccccc3)n2)n2n1CC(N1CCOCC1)C2, the solvents is CN(C)C=O, the agents is [Na+] and [H-]

Using O=C1CCc2nc3cc(C#Cc4cccc(F)c4)ccc3c(=O)n2C1 to produce O=c1c2ccc(C#Cc3cccc(F)c3)cc2nc2n1CC(O)CC2, the solvents is C1CCOC1, the agents is [Na+] and [BH4-]

Using O=C1CCC(=O)N1Br and Cc1ccc(F)c(C(C)(C)C)c1 to produce CC(C)(C)c1cc(CBr)ccc1F, the solvents is ClC(Cl)(Cl)Cl, the agents is O=C(OOC(=O)c1ccccc1)c1ccccc1

Using O=C(O)c1ccccc1F and O=[N+]([O-])c1cnc(OC2CCNCC2)c2ccccc12 to produce O=C(c1ccccc1F)N1CCC(Oc2ncc([N+](=O)[O-])c3ccccc23)CC1, the solvents is C1CCOC1, the agents is On1nnc2ccccc21 and C(=NC1CCCCC1)=NC1CCCCC1

Using C=CCCC=C and C[SiH](C)Cl to produce CCCCC=C[Si](C)(C)Cl, the solvents is Cc1ccccc1C, the agents is [Pt]

Using CCCOc1ccc(Br)cc1CNCC and N#Cc1ccc(Cl)nn1 to produce CCCOc1ccc(Br)cc1CN(CC)c1ccc(C#N)nn1, the solvents is CCOC(C)=O and CN1CCCC1=O, the agents is [Na+] and Cl and O=C([O-])O

Using CC(C)(C)OC(=O)N[C@@H](Cc1ccncc1)C(=O)O and CCN(C(C)C)C(C)C to produce CC(C)(C)OC(=O)N[C@H](Cc1ccncc1)C(=O)N1CCCC1, the solvents is C1CCNC1 and ClCCl, the agents is CC(C)COC(=O)Cl

Using O=C(O)c1cccc(CCl)c1 and C=CCCOCc1ccc(C(=O)O)cc1 to produce CCCOCc1cccc(C(=O)O)c1, the solvents is CCCO, the agents is [Na+] and [H-]

Using CCOC(=O)COC1C2OC3(OCC45CC6C(C)CCC6C6(C=O)CC4C=C(C(C)C)C65C(=O)OC(c4ccccc4)c4ccccc4)OC2OC1C3O to produce CCOC(=O)COC1C2OC3(OCC45CC6C(C)CCC6C6(C=O)CC4C=C(C(C)C)C65C(=O)O)OC2OC1C3O, the solvents is CCOC(C)=O, the agents is [C] and [Pd]

Using O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CBr)CS[C@H]12 and O=C([O-])CCCO to produce O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)C(COC(=O)CCCO)=CS[C@H]12, the solvents is CCOC(C)=O and CN(C)P(=O)(N(C)C)N(C)C, the agents is [Na+]

Using O=C(Cl)OCC(Cl)(Cl)Cl and Cc1ccc(-n2nc(C(C)(C)C)cc2N)cc1 to produce Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1, the solvents is CCOC(C)=O and O, the agents is [Na+] and Cl and [OH-]

Using CCOC(=O)c1c(C)nc(N2CCc3ccccc3C2)nc1C to produce Cc1nc(N2CCc3ccccc3C2)nc(C)c1C(=O)O, the solvents is CCO and O, the agents is [Na+] and [OH-]

Using CC(C)(C)OC(=O)N1CCC(C=O)CC1 and CCCNC1CCc2ccc(O)cc2C1 to produce CCCN(CC1CCN(C(=O)OC(C)(C)C)CC1)C1CCc2ccc(O)cc2C1, the solvents is CC(Cl)Cl, the agents is CC(=O)O[BH-](OC(C)=O)OC(C)=O and [Na+]

Using C=CCO[C@H]1Cc2ccc(OC)cc2[C@H]1NC(=O)C(F)(F)F to produce C=CCO[C@H]1Cc2ccc(OC)cc2[C@H]1N, the solvents is CO, the agents is O=C([O-])[O-] and [K+]

Using CN(C)C=O and Cc1ccn(-c2cccc(F)c2)n1 to produce Cc1nn(-c2cccc(F)c2)cc1C=O, the solvents is O=P(Cl)(Cl)Cl, the agents is [Na+] and O=C([O-])O

Using N[C@@H](CS)C(=O)O and COC(=O)SCCCN1C(=O)NCC1c1ccccc1 to produce N[C@@H](CSSCCCN1C(=O)NCC1c1ccccc1)C(=O)O, the solvents is O and CO, the agents is Cl

Using Cc1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1 and CC1=C(C)C(C)([Ti](Cl)(Cl)Cl)C(C)=C1C to produce CC1=C(C)C(C)([Ti](Cl)(Cl)Oc2c(-c3ccccc3)cc(C)cc2-c2ccccc2)C(C)=C1C, the solvents is Cc1ccccc1, the agents is [Na+] and [H-]

Using CC(C)(C)OC(=O)N[C@H]1CC[C@H](C=CS(C)(=O)=O)CC1 to produce CC(C)(C)OC(=O)N[C@H]1CC[C@H](CCS(C)(=O)=O)CC1, the solvents is CO, the agents is [Pd]

Using Sc1nc2ccccc2[nH]1 and O=C(CBr)c1ccccc1 to produce O=C(CSc1nc2ccccc2[nH]1)c1ccccc1, the solvents is CO, the agents is [Na+] and [OH-]

Using CCCC[Sn](CCCC)(CCCC)c1cncs1 and CS(=O)(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1 to produce CS(=O)(=O)N1CCN(Cc2cc3nc(-c4cncs4)nc(N4CCOCC4)c3s2)CC1, the solvents is CC(=O)N(C)C, the agents is c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

Using [NH4+] and CCOC(=O)c1cn([C@@H](CSc2cccc3ccccc23)[C@H](C)O)cn1 to produce C[C@H](O)[C@H](CSc1cccc2ccccc12)n1cnc(C(N)=O)c1, the solvents is COCCOC, the agents is [OH-]

Using O=Cc1ccc(C(F)(F)F)cc1 and COC(=O)c1ccc(I)cc1 to produce COC(=O)c1ccc(C(O)c2ccc(C(F)(F)F)cc2)cc1, the solvents is C1CCOC1, the agents is CC(C)[Mg]Cl and N#N

Using O=C=O and COc1c(Br)ccc2[nH]nc(-c3cccc(F)c3)c12 to produce COc1c(C(=O)O)ccc2[nH]nc(-c3cccc(F)c3)c12, the solvents is CCCCCC and C1CCOC1, the agents is [Cl-] and [NH4+] and [Li]CCCC

Using FCCBr and Clc1ncnc2cc[nH]c12 to produce FCCn1ccc2ncnc(Cl)c21, the solvents is CN(C)C=O and O, the agents is O=C([O-])[O-] and [Cs+]

Using C[Si](C)(C)OC1=CC(c2ccc(Cl)nc2)CC1 to produce O=C1CCC(c2ccc(Cl)nc2)C1, the solvents is CCOC(C)=O and C1CCOC1, the agents is [Na+] and Cl and O=C([O-])O

Using C#CCOc1ccc(C[C@H](N)C(=O)O)cc1 and NC(Cc1ccccc1)C(=O)O to produce C#CCOC(=O)C(N)Cc1ccc(OCC#C)cc1, the solvents is O and CO, the agents is [Na+] and Cl and [OH-]

Using CCOC(=O)CC[C@@H](NC(=O)CCC(NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C)C(=O)OCC to produce CCOC(=O)CC[C@@H](NC(=O)CCC(N)C(=O)OC(C)(C)C)C(=O)OCC, the solvents is CCO, the agents is [Pd]

Using CC(C)n1nc(CN=[N+]=[N-])c(Cc2ccncc2)c1Sc1cc(Cl)cc(Cl)c1 to produce CC(C)n1nc(CN)c(Cc2ccncc2)c1Sc1cc(Cl)cc(Cl)c1, the solvents is CCOC(C)=O, the agents is [Pd]

Using O=[N+]([O-])c1ccc(F)c(F)c1F and CCOC(=O)CC(C)=O to produce CC(=O)Cc1c([N+](=O)[O-])ccc(F)c1F, the solvents is C1CCOC1, the agents is [Na+] and [H-]

Using O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1 and OCc1nc2cccnc2n1Cc1ccc(-c2ccccc2)cc1 to produce O=C1SC(Cc2ccc(OCc3nc4cccnc4n3Cc3ccc(-c4ccccc4)cc3)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1, the solvents is c1ccccc1, the agents is CCCCP(CCCC)CCCC and O=C(N=NC(=O)N1CCCCC1)N1CCCCC1

Using CC(=O)CCC(C)=O and Nc1ccc(Br)cn1 to produce Cc1ccc(C)n1-c1ccc(Br)cn1, the solvents is CC(=O)O and C1CCCCC1, the agents is C

Using COc1cc(N)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1 and O=C(Cl)OCCCl to produce COc1cc(N2CCOC2=O)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1, the solvents is C1CCOC1 and CCN(CC)CC, the agents is [Na+] and O=C([O-])O

Using COc1ccc(CC(Cc2ccc(OC)cc2)N2C(=O)[C@H]([C@@H](C)OC(=O)OCc3ccccc3)[C@H]2[C@@H](C)CO[Si](C)(C)C(C)(C)C)cc1 to produce COc1ccc(CC(Cc2ccc(OC)cc2)N2C(=O)[C@H]([C@@H](C)OC(=O)OCc3ccccc3)[C@H]2[C@@H](C)CO)cc1, the solvents is CCOC(C)=O and CO, the agents is Cl

Using Cc1cc(Cl)ccc1OCC(=O)O to produce Cc1cc(Cl)ccc1OCC(=O)[O-], the solvents is CO, the agents is [K+] and [OH-]

Using CCOCNc1ncccc1C(=O)NCc1ccc(Oc2ccccc2)s1 to produce CNc1ncccc1C(=O)NCc1ccc(Oc2ccccc2)s1, the solvents is O and CS(C)=O, the agents is [Na+] and [BH4-]

Using CCOC(=O)c1ccc(F)c(NS(=O)(=O)c2c(F)cccc2F)c1 and Cc1ccnc(Cl)n1 to produce O=C(Cc1ccnc(Cl)n1)c1ccc(F)c(NS(=O)(=O)c2c(F)cccc2F)c1, the solvents is C1CCOC1, the agents is C[Si](C)(C)[N-][Si](C)(C)C and [Li+]

Using OCC(Cl)(Cl)Cl and CCOC(Cc1ccc(C(C)(C)O[SiH2]C(C)(C)C)cc1)C(=O)O to produce CCOC(Cc1ccc(C(C)(C)O[SiH2]C(C)(C)C)cc1)C(=O)OCC(Cl)(Cl)Cl, the solvents is ClCCl and ClCCCl, the agents is CN(C)c1ccncc1 and Cl

Using CN1CCC(OC(c2cccc(C=O)c2)c2nc3ccccc3[nH]2)CC1 to produce CN1CCC(OC(c2cccc(CO)c2)c2nc3ccccc3[nH]2)CC1, the solvents is CO, the agents is [Na+] and [BH4-]

Using CCOC(=O)C1=NCc2c(c3ccccc3n2S(=O)(=O)c2ccc(C)cc2)N1 to produce O=C(O)c1ncc2[nH]c3ccccc3c2n1, the solvents is Cc1ccccc1C, the agents is [C] and [Pd]

Using CN1CCN(c2cc(CS(=O)(=O)c3cccc4ccccc34)c([N+](=O)[O-])c(OCCCl)c2)CC1 to produce CN1CCN(c2cc(CS(=O)(=O)c3cccc4ccccc34)c(N)c(OCCCl)c2)CC1, the solvents is C1CCOC1 and CO, the agents is [Pd]

Using ClCC1CO1 and CC(=O)N1CCc2[nH]nc(-c3ccc(Br)cc3)c2C1 to produce CC(=O)N1CCc2c(c(-c3ccc(Br)cc3)nn2CC2CO2)C1, the solvents is CCOC(C)=O and CN(C)C=O, the agents is O=C([O-])[O-] and [Cs+]

Using CC(C)OC(=O)[C@@H](O)[C@@H](Cc1ccccc1)C(=O)OC(C)C to produce O=C(O)[C@@H](O)[C@@H](Cc1ccccc1)C(=O)O, the solvents is O and C1CCOC1, the agents is [K+] and [OH-]

Using Cc1ccc(S(=O)(=O)OC[C@H]2CCCN2C(=O)OC(C)(C)C)cc1 and Oc1ccc(OCc2ccccc2)cc1 to produce CC(C)(C)OC(=O)N1CCCC1COc1ccc(OCc2ccccc2)cc1, the solvents is CN(C)C=O, the agents is [Na+] and [H-]

Using CS(=O)(=O)Cl and O=S(=O)([O-])c1ccc(O)cc1 to produce CS(=O)(=O)Oc1ccc(S(=O)(=O)[O-])cc1, the solvents is O, the agents is [Cl-] and [Na+] and [OH-]

Using CC(CO)N1CCNCC1 and COc1cc(CCc2cc(NC(=O)c3ccc(F)cc3)[nH]n2)cc(OC)c1 to produce COc1cc(CCc2cc(NC(=O)c3ccc(N4CCN(C(C)CO)CC4)cc3)[nH]n2)cc(OC)c1, the solvents is CS(C)=O and CCN(C(C)C)C(C)C, the agents is Cl

Using CCOC(=O)c1cn(-c2cc(NC(=O)OC(C)(C)C)c(F)cc2F)c2c(Cl)c(F)c(F)cc2c1=O and [N-]=[N+]=[N-] to produce CCOC(=O)c1cn(-c2cc(NC(=O)OC(C)(C)C)c(F)cc2F)c2c(Cl)c(N=[N+]=[N-])c(F)cc2c1=O, the solvents is CCOC(C)=O and CN(C)C=O, the agents is [Na+]

Using Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1C(=O)CSC(c1ccccc1)(c1ccccc1)c1ccccc1 to produce Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1C(=O)CS, the solvents is O=C(O)C(F)(F)F and ClCCl, the agents is CC[SiH](CC)CC

Using Sc1nc2ccc(Cl)nc2s1 and C1CCOC1 to produce CSc1nc2ccc(Cl)nc2s1, the solvents is CCOC(C)=O and CI, the agents is O=C([O-])[O-] and [K+]

Using COC(=O)CCC(=O)c1ccc(OC)c(OC)c1OC to produce COc1ccc(C(=O)CCC(=O)O)c(OC)c1OC, the solvents is O and CO, the agents is [Na+] and [OH-]

Using O=C(N=C=S)c1ccccc1 and COc1cc(N)ccc1Cl to produce COc1cc(NC(N)=S)ccc1Cl, the solvents is O and C1CCOC1, the agents is O=C([O-])[O-] and [K+]

Using CC(C)(C)OC(=O)Nc1ccc2c(c1)C(=O)N[C@H](C(=O)O)C2 and NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c[nH]cn1 to produce CC(C)(C)OC(=O)Nc1ccc2c(c1)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(N)=O)C2, the solvents is CN(C)C=O and CCN(CC)CC, the agents is O=C1CCC(=O)N1O and C(=NC1CCCCC1)=NC1CCCCC1

Using COC(=O)c1cc(Cl)cc(NC2CCOCC2)c1C and O=C([O-])[O-] to produce COC(=O)c1cc(Cl)cc(N(C)C2CCOCC2)c1C, the solvents is CC#N and CI, the agents is [Cs+]

Using [Cl-] and O=C(O)CC12CC3CC(CC(C3)C1)C2 to produce O=C(O)CC12CC3CC(CC(Cl)(C3)C1)C2, the solvents is ClC(Cl)(Cl)Cl and CC(C)(C)O, the agents is O=S(=O)(O)O and [Na+]

Using Nc1ccn2nc(N3CCCC3)nc2c1 and CCOC(=O)c1cnn(C)c1C(=O)O to produce CCOC(=O)c1cnn(C)c1C(=O)Nc1ccn2nc(N3CCCC3)nc2c1, the solvents is C1CCOC1 and CCN(C(C)C)C(C)C, the agents is CCCP(=O)=O

Using O=C1CCN2CCCC2C1 and NNc1cccc(Br)c1 to produce Brc1ccc2c3c([nH]c2c1)CC1CCCN1C3, the solvents is CCO, the agents is Cl

Using BrCc1ccc(Br)cc1 and C=CCCBr to produce C=CCCCc1ccc(Br)cc1, the solvents is C1CCOC1, the agents is [Mg] and Cl

Using COC(=O)c1cnc2snnc2c1 to produce O=C(O)c1cnc2snnc2c1, the solvents is C1CCOC1, the agents is [Na+] and [OH-]

Using CCCCCNC(=O)N(C)c1cccc(-c2cnc(C=CC(=O)[O-])nc2)c1 to produce CCCCCNC(=O)N(C)c1cccc(-c2cnc(C=CC(=O)O)nc2)c1, the solvents is O and C1CCOC1, the agents is [Na+] and [OH-]

Using COC(=O)c1c2ccccc2[n+](C)c2ccc(Cl)cc12 to produce COC(=O)C1c2ccccc2N(C)c2ccc(Cl)cc21, the solvents is O and CO, the agents is [K+] and [BH4-] and O=S(=O)([O-])[O-]

Using CC(C)n1c(C=O)c(-c2ccc(F)cc2)c2ccccc21 and CCOP(=O)(CC(=O)N(C)OC)OCC to produce CON(C)C(=O)/C=C/c1c(-c2ccc(F)cc2)c2ccccc2n1C(C)C, the solvents is O and C1CCOC1, the agents is [Na+] and [H-]

Using On1nnc2ccccc21 and CCC1c2sc(C(=O)O)nc2CCN1/C(=N/c1ccccc1)SC to produce CSC(=Nc1ccccc1)N1CCc2nc(C(=O)Nc3ccccc3N)sc2C1, the solvents is CN(C)C=O and CCN(CC)CC, the agents is CCN=C=NCCCN(C)C

Using NC(=O)CCl and CC(C)(C)OC(=O)N1CCN(c2ccc(O)c(C=O)c2)CC1 to produce CC(C)(C)OC(=O)N1CCN(c2ccc3oc(C(N)=O)cc3c2)CC1, the solvents is CN1CCCC1=O, the agents is O=C([O-])[O-] and [K+]

Using COc1ccc2cc(Oc3ccc([N+](=O)[O-])cc3)ccc2c1 to produce COc1ccc2cc(Oc3ccc(N)cc3)ccc2c1, the solvents is CCOC(C)=O, the agents is [Pd]

Using CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)cc(OCc3ccccc3)c3ccccc32)CC1 to produce CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)cc(O)c3ccccc32)CC1, the solvents is C1CCOC1 and CO, the agents is [Pd]

Using CCOC(=O)C(Cc1cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(C)c1)C(O)([PH2]=O)C(NC(=O)OCc1ccccc1)C(C)C to produce Cc1cc(CC(C(=O)O)C(O)([PH2]=O)C(NC(=O)OCc2ccccc2)C(C)C)cnc1NC(=O)OC(C)(C)C, the solvents is CC#N and CO, the agents is [Li+] and [OH-]

Using CC(C)(C)CCI and CC(C(=O)O)c1ccccc1 to produce CC(C)(C)CCC(C)(C(=O)O)c1ccccc1, the solvents is C1CCOC1, the agents is C[Si](C)(C)[N-][Si](C)(C)C and [Li+]

Using COc1ccc(C)c(N)c1 and O=C(Cl)CCl to produce COc1ccc(C)c(NC(=O)CCl)c1, the solvents is C1CCOC1 and CCN(C(C)C)C(C)C, the agents is Cl

Using [N-]=[N+]=Nc1ccc(Cl)cc1C(=O)c1ccccc1 and NO to produce [N-]=[N+]=Nc1ccc(Cl)cc1C(=NO)c1ccccc1, the solvents is CCO and c1ccncc1, the agents is Cl

Using CCC(C)=O and CC1(C)C(CC=O)CC2CC21C to produce CC(=O)C(C)=CCC1CC2CC2(C)C1(C)C, the solvents is O and CO, the agents is [K+] and [OH-]

Using Brc1ccc(Br)nc1 and OB(O)c1ccc(OCc2ccccc2)c(F)c1 to produce Fc1cc(-c2ccc(Br)cn2)ccc1OCc1ccccc1, the solvents is CCO and Cc1ccccc1, the agents is O=C([O-])[O-] and [Na+] and c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

Using COC(=O)C1=C(NC2CC2)OC(=Cc2c[nH]c3ncccc23)C1=O to produce O=C1C=C(NC2CC2)OC1=Cc1c[nH]c2ncccc12, the solvents is CCO, the agents is [K+] and [OH-]

Using NO and O=C(O)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)cc1 to produce O=C(O)C(=NO)c1ccc(OCCOc2ccc3ccccc3c2)cc1, the solvents is CN(C)C=O, the agents is [Na+] and Cl and [OH-]

Using CCOC(=O)CBr and O=c1[nH]c2ccccc2c(=O)n1Cc1ccc(Cl)c(Cl)c1 to produce CCOC(=O)Cn1c(=O)n(Cc2ccc(Cl)c(Cl)c2)c(=O)c2ccccc21, the solvents is CN(C)C=O, the agents is [Na+] and Cl and [H-]

Using CC(C)c1cc(Oc2c(Br)cc([N+](=O)[O-])c(C(F)(F)F)c2Br)cc(C=O)c1O to produce Cc1cc(Oc2c(Br)cc([N+](=O)[O-])c(C(F)(F)F)c2Br)cc(C(C)C)c1O, the solvents is O=C(O)C(F)(F)F, the agents is CC[SiH](CC)CC

Using O=C1C=CC(=O)C=C1 and CCOC(=O)C[Zn]Br to produce CCOC(=O)CC1(O)C=CC(=O)C=C1, the solvents is CCOC(C)=O and C1CCOC1, the agents is Cl

Using CN(C)C=NS(=O)(=O)c1ccc(Br)s1 and OCC(O)CS to produce NS(=O)(=O)c1ccc(SCC(O)CO)s1, the solvents is CN(C)C=O and O, the agents is [Na+] and [H-]

Using O=Cc1cc2cnccc2o1 to produce OCc1cc2cnccc2o1, the solvents is CO, the agents is [Na+] and [BH4-]

Using Nc1ccc(CC(O)c2ccccc2C(=O)O)cc1 to produce O=C(O)c1ccccc1C(O)Cc1ccc(N(Cc2ccccc2)Cc2ccccc2)cc1, the solvents is CO, the agents is [Pd]

Using CC(C)(C)OC(=O)NC1(C#Cc2ccc(OCCC3=CCC4CC3C4(C)C)cc2)COC(C)(C)OC1 to produce CC(C)(C)OC(=O)NC1(CCc2ccc(OCCC3=CCC4CC3C4(C)C)cc2)COC(C)(C)OC1, the solvents is CCO, the agents is [Pd]

Using CCOC(=O)CCn1nc(-c2cccnc2)c(C#N)c1N to produce N#Cc1c(-c2cccnc2)nn2c1NC(=O)CC2, the solvents is O and C1CCOC1, the agents is [Li]CCCC

Using c1cnc2ccc(Cn3nnc4cnc(-c5cnn(CCOC6CCCCO6)c5)nc43)cc2c1 to produce OCCn1cc(-c2ncc3nnn(Cc4ccc5ncccc5c4)c3n2)cn1, the solvents is O and CO, the agents is Cc1ccc(S(=O)(=O)O)cc1

Using O=C1CCN(c2ccccc2)c2ccccc21 and CCOC(=O)OCC to produce CCOC(=O)C1=C(O)c2ccccc2N(c2ccccc2)C1, the solvents is c1ccccc1, the agents is [Na+] and [H-]

Using CC(=O)NNC(C)=O and ClCCOCCCl to produce CC(=O)n1ccoccn1C(C)=O, the solvents is CC(C)O and CS(C)=O, the agents is O=C([O-])[O-] and [K+] and [OH-]

Using COc1cc(C(=O)OC(C)(C)C)ccc1CBr and COc1cc(C(=O)NS(=O)(=O)c2ccccc2)ccc1Cn1cc(CCC(=O)N2CCOCC2)c2ccc(C(=O)NCC3CCCC3)cc21 to produce COc1cc(C(=O)O)ccc1Cn1cc(CCC(=O)N2CCOCC2)c2ccc(C(=O)NCC3CCCC3)cc21, the solvents is O and C1COCCN1, the agents is CN(C)c1ccncc1 and Cl

Using C[Si](C)(C)N1CCCC1=O and c1ccc2c(c1)OCCC1OC21 to produce O=C1CCCN1[C@@H]1c2ccccc2OCC[C@H]1O, the solvents is O and C1CCOC1, the agents is [F-] and CCCC[N+](CCCC)(CCCC)CCCC

Using COc1cccc2cc(CNCCNC(=O)C34CC5CC(CC(C5)C3)C4)oc12 to produce COc1cccc2cc(CN(C)CCNC(=O)C34CC5CC(CC(C5)C3)C4)oc12, the solvents is CCO and O, the agents is Cl and C=O and [Pd]

Using CI and CCOC(=O)Cc1cccc(OCOC)c1 to produce CCOC(=O)C(C)c1cccc(OCOC)c1, the solvents is CN(C)C=O, the agents is [Na+] and [H-]

Using N#Cc1cc(C(F)(F)F)ccc1F and Nc1ccccc1[N+](=O)[O-] to produce N#Cc1cc(C(F)(F)F)ccc1Nc1ccccc1[N+](=O)[O-], the solvents is CN(C)C=O, the agents is O=C([O-])[O-] and [Cs+] and Cl

Using CCn1nc(C(N)=O)cc1CCS(C)(=O)=O to produce CCn1nc(C#N)cc1CCS(C)(=O)=O, the solvents is O=P(Cl)(Cl)Cl, the agents is [NH4+] and [OH-]

Using CC(=O)OCC1(COC(C)=O)Sc2cc3c(cc2S1)SC(COC(C)=O)(COC(C)=O)S3 to produce OCC1(CO)Sc2cc3c(cc2S1)SC(CO)(CO)S3, the solvents is CO, the agents is O=C([O-])[O-] and [K+]

Using COc1cc(Cn2c3ccccc3c3c(OC(C)(C)C(=O)O)cccc32)ccc1OCc1nc(-c2ccccc2)oc1C to produce COc1cc(Cn2c3ccccc3c3c(OC(C)(C)C(=O)[O-])cccc32)ccc1OCc1nc(-c2ccccc2)oc1C, the solvents is CC(C)O, the agents is [Na+] and [OH-]