Scent of Health (S-OH) Dataset

The Scent of Health (S-OH) dataset is the largest public clinical electronic nose (eNose) collection for non-invasive disease screening via exhaled breath analysis. It comprises 1,234 patients across nine diagnostic groups (healthy controls and eight diseases), each providing a 17-channel multivariate time series of breath measurements.

Property	Value
Patients	1,234
Diagnostic groups	9 (healthy + 8 diseases)
Time series channels	17 (eNose sensors) + auxiliary sensors
Sampling rate	0.4 Hz
Duration per sample	895 seconds (~15 minutes)
Collection period	13 consecutive weeks
Clinical sites	2

Diagnostic Groups

ICD-10 Code	Diagnosis	Count
Z00	Healthy controls	256
E11	Diabetes mellitus type II	128
K29	Gastritis and duodenitis	138
K76	Non-alcoholic fatty liver disease	128
B18	Hepatitis B/C	138
C34	Lung cancer	100
N18	Chronic renal failure	128
J44	COPD	100
A15	Respiratory tuberculosis	118
Total		1,234

Demographics:

• Age range: 18–89 years (mean 53.9, std 13.4)
• Gender: 690 female (55.9%), 544 male (44.1%)

Dataset Structure

File 1: S-OH_metadata.csv

CSV file containing patient metadata with the following columns:

Column	Description
Patient_id	Unique patient identifier
Patient_age	Age in years
Patient_gender	Gender (male or female)
Diagnosis	ICD-10 diagnosis code
D_class	Disease class (0–8)
D_bin_class	Binary class for one-vs-rest classification
Datetime	Collection timestamp
Week	Collection week (1–13)
Site	Clinical site (MONIKI or CRIT)

File 2: S-OH_data_dict.json

JSON dictionary where each key is a patient ID (as string) with the following structure:

{
    "patient_id": int,
    "patient_diag_class": int,
    "startDateTime": "ISO timestamp",
    "startTimeGases": int,
    "endTimeGases": int,
    "durationSec": int,
    "sensors": [
        {
            "id": "enose",
            "sampleRate": 0.4,
            "channels": [
                {"id": "R1", "samples": [float, ...]},
                {"id": "R2", "samples": [float, ...]},
                ...
                {"id": "R17", "samples": [float, ...]},
                {"id": "humidity", "samples": [float, ...]},
                {"id": "temperature", "samples": [float, ...]}
            ]
        },
        {
            "id": "ze03",
            "sampleRate": 0.4,
            "channels": [{"id": "0", "samples": [float, ...]}]
        },
        {
            "id": "mhz14",
            "sampleRate": 0.4,
            "channels": [{"id": "0", "samples": [float, ...]}]
        },
        {
            "id": "ze08",
            "sampleRate": 0.4,
            "channels": [{"id": "0", "samples": [float, ...]}]
        },
        {
            "id": "bme280",
            "sampleRate": 0.4,
            "channels": [
                {"id": "pressure", "samples": [float, ...]},
                {"id": "temperature", "samples": [float, ...]},
                {"id": "humidity", "samples": [float, ...]}
            ]
        }
    ]
}

eNose Channels (17 channels)

The eNose sensor array consists of 17 channels printed on a single chip:

Channel ID	Material
R1–R17	ZnO and metal-doped ZnO (In-ZnO, Ag-ZnO, Ce-ZnO, Ni-ZnO)

Auxiliary Sensors

Sensor ID	Measurements
ze03	Ozone (O₃)
mhz14	Carbon dioxide (CO₂)
ze08	Carbon monoxide (CO)
bme280	Pressure, temperature, humidity

Temporal Train/Test Splits

The dataset includes explicit temporal splits to enable drift-aware evaluation. For each disease, test weeks were selected to be temporally separated from training weeks, simulating real-world deployment conditions.

Ethics

• The study protocol was approved by the Local Ethics Committee at Moscow Regional Research and Clinical Institute (MONIKI) and Central Research Institute of Tuberculosis (CRIT).

• All participants provided written informed consent.

Citation

If you use this dataset in your research, please cite:

License

This dataset is released under the MIT License. You are free to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the dataset, subject to the following conditions:

Permission is hereby granted, free of charge, to any person obtaining a copy of this dataset and associated documentation files (the "Dataset"), to deal in the Dataset without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Dataset, and to permit persons to whom the Dataset is furnished to do so, subject to the following conditions:

The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Dataset.

THE DATASET IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE DATASET OR THE USE OR OTHER DEALINGS IN THE DATASET.

Contact

For questions or issues, please open an issue on this repository or contact the authors (see paper for details).