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Answer (law)
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In law, an answer was originally a solemn assertion in opposition to someone or something, and thus generally any counter-statement or defense, a reply to a question or response, or objection, or a correct solution of a problem.
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Answer (law)
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In the common law, an answer is the first pleading by a defendant, usually filed and served upon the plaintiff within a certain strict time limit after a civil complaint or criminal information or indictment has been served upon the defendant. It may have been preceded by an optional "pre-answer" motion to dismiss or demurrer; if such a motion is unsuccessful, the defendant must file an answer to the complaint or risk an adverse default judgment.
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Answer (law)
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In a criminal case, there is usually an arraignment or some other kind of appearance before the defendant comes to court. The pleading in the criminal case, which is entered on the record in open court, is usually either guilty or not guilty. Generally speaking in private, civil cases there is no plea entered of guilt or innocence. There is only a judgment that grants money damages or some other kind of equitable remedy such as restitution or a permanent injunction. Criminal cases may lead to fines or other punishment, such as imprisonment.
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Answer (law)
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The famous Latin Responsa Prudentium ("answers of the learned ones") were the accumulated views of many successive generations of Roman lawyers, a body of legal opinion which gradually became authoritative. During debates of a contentious nature, deflection, colloquially known as 'changing the topic', has been widely observed, and is often seen as a failure to answer a question. Notes Common law
Legal documents
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Anatomy
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Anatomy (Greek anatomē, 'dissection') is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science which deals with the structural organization of living things. It is an old science, having its beginnings in prehistoric times. Anatomy is inherently tied to developmental biology, embryology, comparative anatomy, evolutionary biology, and phylogeny, as these are the processes by which anatomy is generated, both over immediate and long-term timescales. Anatomy and physiology, which study the structure and function of organisms and their parts respectively, make a natural pair of related disciplines, and are often studied together. Human anatomy is one of the essential basic sciences that are applied in medicine.
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Anatomy
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The discipline of anatomy is divided into macroscopic and microscopic. Macroscopic anatomy, or gross anatomy, is the examination of an animal's body parts using unaided eyesight. Gross anatomy also includes the branch of superficial anatomy. Microscopic anatomy involves the use of optical instruments in the study of the tissues of various structures, known as histology, and also in the study of cells.
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Anatomy
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The history of anatomy is characterized by a progressive understanding of the functions of the organs and structures of the human body. Methods have also improved dramatically, advancing from the examination of animals by dissection of carcasses and cadavers (corpses) to 20th century medical imaging techniques including X-ray, ultrasound, and magnetic resonance imaging. Definition
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Anatomy
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Derived from the Greek anatomē "dissection" (from anatémnō "I cut up, cut open" from ἀνά aná "up", and τέμνω témnō "I cut"), anatomy is the scientific study of the structure of organisms including their systems, organs and tissues. It includes the appearance and position of the various parts, the materials from which they are composed, their locations and their relationships with other parts. Anatomy is quite distinct from physiology and biochemistry, which deal respectively with the functions of those parts and the chemical processes involved. For example, an anatomist is concerned with the shape, size, position, structure, blood supply and innervation of an organ such as the liver; while a physiologist is interested in the production of bile, the role of the liver in nutrition and the regulation of bodily functions.
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Anatomy
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The discipline of anatomy can be subdivided into a number of branches including gross or macroscopic anatomy and microscopic anatomy. Gross anatomy is the study of structures large enough to be seen with the naked eye, and also includes superficial anatomy or surface anatomy, the study by sight of the external body features. Microscopic anatomy is the study of structures on a microscopic scale, along with histology (the study of tissues), and embryology (the study of an organism in its immature condition).
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Anatomy
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Anatomy can be studied using both invasive and non-invasive methods with the goal of obtaining information about the structure and organization of organs and systems. Methods used include dissection, in which a body is opened and its organs studied, and endoscopy, in which a video camera-equipped instrument is inserted through a small incision in the body wall and used to explore the internal organs and other structures. Angiography using X-rays or magnetic resonance angiography are methods to visualize blood vessels.
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Anatomy
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The term "anatomy" is commonly taken to refer to human anatomy. However, substantially the same structures and tissues are found throughout the rest of the animal kingdom and the term also includes the anatomy of other animals. The term zootomy is also sometimes used to specifically refer to non-human animals. The structure and tissues of plants are of a dissimilar nature and they are studied in plant anatomy. Animal tissues
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Anatomy
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The kingdom Animalia contains multicellular organisms that are heterotrophic and motile (although some have secondarily adopted a sessile lifestyle). Most animals have bodies differentiated into separate tissues and these animals are also known as eumetazoans. They have an internal digestive chamber, with one or two openings; the gametes are produced in multicellular sex organs, and the zygotes include a blastula stage in their embryonic development. Metazoans do not include the sponges, which have undifferentiated cells.
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Anatomy
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Unlike plant cells, animal cells have neither a cell wall nor chloroplasts. Vacuoles, when present, are more in number and much smaller than those in the plant cell. The body tissues are composed of numerous types of cell, including those found in muscles, nerves and skin. Each typically has a cell membrane formed of phospholipids, cytoplasm and a nucleus. All of the different cells of an animal are derived from the embryonic germ layers. Those simpler invertebrates which are formed from two germ layers of ectoderm and endoderm are called diploblastic and the more developed animals whose structures and organs are formed from three germ layers are called triploblastic. All of a triploblastic animal's tissues and organs are derived from the three germ layers of the embryo, the ectoderm, mesoderm and endoderm.
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Anatomy
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Animal tissues can be grouped into four basic types: connective, epithelial, muscle and nervous tissue.
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Anatomy
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Connective tissue
Connective tissues are fibrous and made up of cells scattered among inorganic material called the extracellular matrix. Connective tissue gives shape to organs and holds them in place. The main types are loose connective tissue, adipose tissue, fibrous connective tissue, cartilage and bone. The extracellular matrix contains proteins, the chief and most abundant of which is collagen. Collagen plays a major part in organizing and maintaining tissues. The matrix can be modified to form a skeleton to support or protect the body. An exoskeleton is a thickened, rigid cuticle which is stiffened by mineralization, as in crustaceans or by the cross-linking of its proteins as in insects. An endoskeleton is internal and present in all developed animals, as well as in many of those less developed.
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Epithelium
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Anatomy
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Epithelial tissue is composed of closely packed cells, bound to each other by cell adhesion molecules, with little intercellular space. Epithelial cells can be squamous (flat), cuboidal or columnar and rest on a basal lamina, the upper layer of the basement membrane, the lower layer is the reticular lamina lying next to the connective tissue in the extracellular matrix secreted by the epithelial cells. There are many different types of epithelium, modified to suit a particular function. In the respiratory tract there is a type of ciliated epithelial lining; in the small intestine there are microvilli on the epithelial lining and in the large intestine there are intestinal villi. Skin consists of an outer layer of keratinized stratified squamous epithelium that covers the exterior of the vertebrate body. Keratinocytes make up to 95% of the cells in the skin. The epithelial cells on the external surface of the body typically secrete an extracellular matrix in the form of a cuticle. In simple animals this may just be a coat of glycoproteins. In more advanced animals, many glands are formed of epithelial cells.
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Anatomy
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Muscle tissue
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Anatomy
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Muscle cells (myocytes) form the active contractile tissue of the body. Muscle tissue functions to produce force and cause motion, either locomotion or movement within internal organs. Muscle is formed of contractile filaments and is separated into three main types; smooth muscle, skeletal muscle and cardiac muscle. Smooth muscle has no striations when examined microscopically. It contracts slowly but maintains contractibility over a wide range of stretch lengths. It is found in such organs as sea anemone tentacles and the body wall of sea cucumbers. Skeletal muscle contracts rapidly but has a limited range of extension. It is found in the movement of appendages and jaws. Obliquely striated muscle is intermediate between the other two. The filaments are staggered and this is the type of muscle found in earthworms that can extend slowly or make rapid contractions. In higher animals striated muscles occur in bundles attached to bone to provide movement and are often arranged in antagonistic sets. Smooth muscle is found in the walls of the uterus, bladder, intestines, stomach, oesophagus, respiratory airways, and blood vessels. Cardiac muscle is found only in the heart, allowing it to contract and pump blood round the body.
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Anatomy
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Nervous tissue
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Nervous tissue is composed of many nerve cells known as neurons which transmit information. In some slow-moving radially symmetrical marine animals such as ctenophores and cnidarians (including sea anemones and jellyfish), the nerves form a nerve net, but in most animals they are organized longitudinally into bundles. In simple animals, receptor neurons in the body wall cause a local reaction to a stimulus. In more complex animals, specialized receptor cells such as chemoreceptors and photoreceptors are found in groups and send messages along neural networks to other parts of the organism. Neurons can be connected together in ganglia. In higher animals, specialized receptors are the basis of sense organs and there is a central nervous system (brain and spinal cord) and a peripheral nervous system. The latter consists of sensory nerves that transmit information from sense organs and motor nerves that influence target organs. The peripheral nervous system is divided into the somatic nervous system which conveys sensation and controls voluntary muscle, and the autonomic nervous system which involuntarily controls smooth muscle, certain glands and internal organs, including the stomach.
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Anatomy
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Vertebrate anatomy
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Anatomy
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All vertebrates have a similar basic body plan and at some point in their lives, mostly in the embryonic stage, share the major chordate characteristics; a stiffening rod, the notochord; a dorsal hollow tube of nervous material, the neural tube; pharyngeal arches; and a tail posterior to the anus. The spinal cord is protected by the vertebral column and is above the notochord and the gastrointestinal tract is below it. Nervous tissue is derived from the ectoderm, connective tissues are derived from mesoderm, and gut is derived from the endoderm. At the posterior end is a tail which continues the spinal cord and vertebrae but not the gut. The mouth is found at the anterior end of the animal, and the anus at the base of the tail. The defining characteristic of a vertebrate is the vertebral column, formed in the development of the segmented series of vertebrae. In most vertebrates the notochord becomes the nucleus pulposus of the intervertebral discs. However, a few vertebrates, such as the sturgeon and the coelacanth retain the notochord into adulthood. Jawed vertebrates are typified by paired appendages, fins or legs, which may be secondarily lost. The limbs of vertebrates are considered to be homologous because the same underlying skeletal structure was inherited from their last common ancestor. This is one of the arguments put forward by Charles Darwin to support his theory of evolution.
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Anatomy
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Fish anatomy
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Anatomy
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The body of a fish is divided into a head, trunk and tail, although the divisions between the three are not always externally visible. The skeleton, which forms the support structure inside the fish, is either made of cartilage, in cartilaginous fish, or bone in bony fish. The main skeletal element is the vertebral column, composed of articulating vertebrae which are lightweight yet strong. The ribs attach to the spine and there are no limbs or limb girdles. The main external features of the fish, the fins, are composed of either bony or soft spines called rays, which with the exception of the caudal fins, have no direct connection with the spine. They are supported by the muscles which compose the main part of the trunk. The heart has two chambers and pumps the blood through the respiratory surfaces of the gills and on round the body in a single circulatory loop. The eyes are adapted for seeing underwater and have only local vision. There is an inner ear but no external or middle ear. Low frequency vibrations are detected by the lateral line system of sense organs that run along the length of the sides of fish, and these respond to nearby movements and to changes in water pressure.
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Anatomy
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Sharks and rays are basal fish with numerous primitive anatomical features similar to those of ancient fish, including skeletons composed of cartilage. Their bodies tend to be dorso-ventrally flattened, they usually have five pairs of gill slits and a large mouth set on the underside of the head. The dermis is covered with separate dermal placoid scales. They have a cloaca into which the urinary and genital passages open, but not a swim bladder. Cartilaginous fish produce a small number of large, yolky eggs. Some species are ovoviviparous and the young develop internally but others are oviparous and the larvae develop externally in egg cases.
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Anatomy
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The bony fish lineage shows more derived anatomical traits, often with major evolutionary changes from the features of ancient fish. They have a bony skeleton, are generally laterally flattened, have five pairs of gills protected by an operculum, and a mouth at or near the tip of the snout. The dermis is covered with overlapping scales. Bony fish have a swim bladder which helps them maintain a constant depth in the water column, but not a cloaca. They mostly spawn a large number of small eggs with little yolk which they broadcast into the water column. Amphibian anatomy
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Anatomy
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Amphibians are a class of animals comprising frogs, salamanders and caecilians. They are tetrapods, but the caecilians and a few species of salamander have either no limbs or their limbs are much reduced in size. Their main bones are hollow and lightweight and are fully ossified and the vertebrae interlock with each other and have articular processes. Their ribs are usually short and may be fused to the vertebrae. Their skulls are mostly broad and short, and are often incompletely ossified. Their skin contains little keratin and lacks scales, but contains many mucous glands and in some species, poison glands. The hearts of amphibians have three chambers, two atria and one ventricle. They have a urinary bladder and nitrogenous waste products are excreted primarily as urea. Amphibians breathe by means of buccal pumping, a pump action in which air is first drawn into the buccopharyngeal region through the nostrils. These are then closed and the air is forced into the lungs by contraction of the throat. They supplement this with gas exchange through the skin which needs to be kept moist.
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Anatomy
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In frogs the pelvic girdle is robust and the hind legs are much longer and stronger than the forelimbs. The feet have four or five digits and the toes are often webbed for swimming or have suction pads for climbing. Frogs have large eyes and no tail. Salamanders resemble lizards in appearance; their short legs project sideways, the belly is close to or in contact with the ground and they have a long tail. Caecilians superficially resemble earthworms and are limbless. They burrow by means of zones of muscle contractions which move along the body and they swim by undulating their body from side to side.
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Anatomy
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Reptile anatomy
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Anatomy
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Reptiles are a class of animals comprising turtles, tuataras, lizards, snakes and crocodiles. They are tetrapods, but the snakes and a few species of lizard either have no limbs or their limbs are much reduced in size. Their bones are better ossified and their skeletons stronger than those of amphibians. The teeth are conical and mostly uniform in size. The surface cells of the epidermis are modified into horny scales which create a waterproof layer. Reptiles are unable to use their skin for respiration as do amphibians and have a more efficient respiratory system drawing air into their lungs by expanding their chest walls. The heart resembles that of the amphibian but there is a septum which more completely separates the oxygenated and deoxygenated bloodstreams. The reproductive system has evolved for internal fertilization, with a copulatory organ present in most species. The eggs are surrounded by amniotic membranes which prevents them from drying out and are laid on land, or develop internally in some species. The bladder is small as nitrogenous waste is excreted as uric acid.
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Anatomy
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Turtles are notable for their protective shells. They have an inflexible trunk encased in a horny carapace above and a plastron below. These are formed from bony plates embedded in the dermis which are overlain by horny ones and are partially fused with the ribs and spine. The neck is long and flexible and the head and the legs can be drawn back inside the shell. Turtles are vegetarians and the typical reptile teeth have been replaced by sharp, horny plates. In aquatic species, the front legs are modified into flippers.
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Tuataras superficially resemble lizards but the lineages diverged in the Triassic period. There is one living species, Sphenodon punctatus. The skull has two openings (fenestrae) on either side and the jaw is rigidly attached to the skull. There is one row of teeth in the lower jaw and this fits between the two rows in the upper jaw when the animal chews. The teeth are merely projections of bony material from the jaw and eventually wear down. The brain and heart are more primitive than those of other reptiles, and the lungs have a single chamber and lack bronchi. The tuatara has a well-developed parietal eye on its forehead.
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Lizards have skulls with only one fenestra on each side, the lower bar of bone below the second fenestra having been lost. This results in the jaws being less rigidly attached which allows the mouth to open wider. Lizards are mostly quadrupeds, with the trunk held off the ground by short, sideways-facing legs, but a few species have no limbs and resemble snakes. Lizards have moveable eyelids, eardrums are present and some species have a central parietal eye.
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Snakes are closely related to lizards, having branched off from a common ancestral lineage during the Cretaceous period, and they share many of the same features. The skeleton consists of a skull, a hyoid bone, spine and ribs though a few species retain a vestige of the pelvis and rear limbs in the form of pelvic spurs. The bar under the second fenestra has also been lost and the jaws have extreme flexibility allowing the snake to swallow its prey whole. Snakes lack moveable eyelids, the eyes being covered by transparent "spectacle" scales. They do not have eardrums but can detect ground vibrations through the bones of their skull. Their forked tongues are used as organs of taste and smell and some species have sensory pits on their heads enabling them to locate warm-blooded prey.
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Crocodilians are large, low-slung aquatic reptiles with long snouts and large numbers of teeth. The head and trunk are dorso-ventrally flattened and the tail is laterally compressed. It undulates from side to side to force the animal through the water when swimming. The tough keratinized scales provide body armour and some are fused to the skull. The nostrils, eyes and ears are elevated above the top of the flat head enabling them to remain above the surface of the water when the animal is floating. Valves seal the nostrils and ears when it is submerged. Unlike other reptiles, crocodilians have hearts with four chambers allowing complete separation of oxygenated and deoxygenated blood.
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Bird anatomy
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Birds are tetrapods but though their hind limbs are used for walking or hopping, their front limbs are wings covered with feathers and adapted for flight. Birds are endothermic, have a high metabolic rate, a light skeletal system and powerful muscles. The long bones are thin, hollow and very light. Air sac extensions from the lungs occupy the centre of some bones. The sternum is wide and usually has a keel and the caudal vertebrae are fused. There are no teeth and the narrow jaws are adapted into a horn-covered beak. The eyes are relatively large, particularly in nocturnal species such as owls. They face forwards in predators and sideways in ducks.
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The feathers are outgrowths of the epidermis and are found in localized bands from where they fan out over the skin. Large flight feathers are found on the wings and tail, contour feathers cover the bird's surface and fine down occurs on young birds and under the contour feathers of water birds. The only cutaneous gland is the single uropygial gland near the base of the tail. This produces an oily secretion that waterproofs the feathers when the bird preens. There are scales on the legs, feet and claws on the tips of the toes. Mammal anatomy
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Mammals are a diverse class of animals, mostly terrestrial but some are aquatic and others have evolved flapping or gliding flight. They mostly have four limbs but some aquatic mammals have no limbs or limbs modified into fins and the forelimbs of bats are modified into wings. The legs of most mammals are situated below the trunk, which is held well clear of the ground. The bones of mammals are well ossified and their teeth, which are usually differentiated, are coated in a layer of prismatic enamel. The teeth are shed once (milk teeth) during the animal's lifetime or not at all, as is the case in cetaceans. Mammals have three bones in the middle ear and a cochlea in the inner ear. They are clothed in hair and their skin contains glands which secrete sweat. Some of these glands are specialized as mammary glands, producing milk to feed the young. Mammals breathe with lungs and have a muscular diaphragm separating the thorax from the abdomen which helps them draw air into the lungs. The mammalian heart has four chambers and oxygenated and deoxygenated blood are kept entirely separate. Nitrogenous waste is excreted primarily as urea.
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Mammals are amniotes, and most are viviparous, giving birth to live young. The exception to this are the egg-laying monotremes, the platypus and the echidnas of Australia. Most other mammals have a placenta through which the developing foetus obtains nourishment, but in marsupials, the foetal stage is very short and the immature young is born and finds its way to its mother's pouch where it latches on to a nipple and completes its development. Human anatomy
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Humans have the overall body plan of a mammal. Humans have a head, neck, trunk (which includes the thorax and abdomen), two arms and hands, and two legs and feet.
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Generally, students of certain biological sciences, paramedics, prosthetists and orthotists, physiotherapists, occupational therapists, nurses, podiatrists, and medical students learn gross anatomy and microscopic anatomy from anatomical models, skeletons, textbooks, diagrams, photographs, lectures and tutorials and in addition, medical students generally also learn gross anatomy through practical experience of dissection and inspection of cadavers. The study of microscopic anatomy (or histology) can be aided by practical experience examining histological preparations (or slides) under a microscope.
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Human anatomy, physiology and biochemistry are complementary basic medical sciences, which are generally taught to medical students in their first year at medical school. Human anatomy can be taught regionally or systemically; that is, respectively, studying anatomy by bodily regions such as the head and chest, or studying by specific systems, such as the nervous or respiratory systems. The major anatomy textbook, Gray's Anatomy, has been reorganized from a systems format to a regional format, in line with modern teaching methods. A thorough working knowledge of anatomy is required by physicians, especially surgeons and doctors working in some diagnostic specialties, such as histopathology and radiology.
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Academic anatomists are usually employed by universities, medical schools or teaching hospitals. They are often involved in teaching anatomy, and research into certain systems, organs, tissues or cells. Invertebrate anatomy
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Invertebrates constitute a vast array of living organisms ranging from the simplest unicellular eukaryotes such as Paramecium to such complex multicellular animals as the octopus, lobster and dragonfly. They constitute about 95% of the animal species. By definition, none of these creatures has a backbone. The cells of single-cell protozoans have the same basic structure as those of multicellular animals but some parts are specialized into the equivalent of tissues and organs. Locomotion is often provided by cilia or flagella or may proceed via the advance of pseudopodia, food may be gathered by phagocytosis, energy needs may be supplied by photosynthesis and the cell may be supported by an endoskeleton or an exoskeleton. Some protozoans can form multicellular colonies.
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Metazoans are a multicellular organism, with different groups of cells serving different functions. The most basic types of metazoan tissues are epithelium and connective tissue, both of which are present in nearly all invertebrates. The outer surface of the epidermis is normally formed of epithelial cells and secretes an extracellular matrix which provides support to the organism. An endoskeleton derived from the mesoderm is present in echinoderms, sponges and some cephalopods. Exoskeletons are derived from the epidermis and is composed of chitin in arthropods (insects, spiders, ticks, shrimps, crabs, lobsters). Calcium carbonate constitutes the shells of molluscs, brachiopods and some tube-building polychaete worms and silica forms the exoskeleton of the microscopic diatoms and radiolaria. Other invertebrates may have no rigid structures but the epidermis may secrete a variety of surface coatings such as the pinacoderm of sponges, the gelatinous cuticle of cnidarians (polyps, sea anemones, jellyfish) and the collagenous cuticle of annelids. The outer epithelial layer may include cells of several types including sensory cells, gland cells and stinging cells. There may also be protrusions such as microvilli, cilia, bristles, spines and tubercles.
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Marcello Malpighi, the father of microscopical anatomy, discovered that plants had tubules similar to those he saw in insects like the silk worm. He observed that when a ring-like portion of bark was removed on a trunk a swelling occurred in the tissues above the ring, and he unmistakably interpreted this as growth stimulated by food coming down from the leaves, and being captured above the ring. Arthropod anatomy Arthropods comprise the largest phylum in the animal kingdom with over a million known invertebrate species.
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Insects possess segmented bodies supported by a hard-jointed outer covering, the exoskeleton, made mostly of chitin. The segments of the body are organized into three distinct parts, a head, a thorax and an abdomen. The head typically bears a pair of sensory antennae, a pair of compound eyes, one to three simple eyes (ocelli) and three sets of modified appendages that form the mouthparts. The thorax has three pairs of segmented legs, one pair each for the three segments that compose the thorax and one or two pairs of wings. The abdomen is composed of eleven segments, some of which may be fused and houses the digestive, respiratory, excretory and reproductive systems. There is considerable variation between species and many adaptations to the body parts, especially wings, legs, antennae and mouthparts.
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Spiders a class of arachnids have four pairs of legs; a body of two segments—a cephalothorax and an abdomen. Spiders have no wings and no antennae. They have mouthparts called chelicerae which are often connected to venom glands as most spiders are venomous. They have a second pair of appendages called pedipalps attached to the cephalothorax. These have similar segmentation to the legs and function as taste and smell organs. At the end of each male pedipalp is a spoon-shaped cymbium that acts to support the copulatory organ.
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Other branches of anatomy
Superficial or surface anatomy is important as the study of anatomical landmarks that can be readily seen from the exterior contours of the body. It enables physicians or veterinary surgeons to gauge the position and anatomy of the associated deeper structures. Superficial is a directional term that indicates that structures are located relatively close to the surface of the body.
Comparative anatomy relates to the comparison of anatomical structures (both gross and microscopic) in different animals.
Artistic anatomy relates to anatomic studies for artistic reasons. History Ancient
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In 1600 BCE, the Edwin Smith Papyrus, an Ancient Egyptian medical text, described the heart, its vessels, liver, spleen, kidneys, hypothalamus, uterus and bladder, and showed the blood vessels diverging from the heart. The Ebers Papyrus (c. 1550 BCE) features a "treatise on the heart", with vessels carrying all the body's fluids to or from every member of the body.
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Ancient Greek anatomy and physiology underwent great changes and advances throughout the early medieval world. Over time, this medical practice expanded by a continually developing understanding of the functions of organs and structures in the body. Phenomenal anatomical observations of the human body were made, which have contributed towards the understanding of the brain, eye, liver, reproductive organs and the nervous system.
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The Hellenistic Egyptian city of Alexandria was the stepping-stone for Greek anatomy and physiology. Alexandria not only housed the biggest library for medical records and books of the liberal arts in the world during the time of the Greeks, but was also home to many medical practitioners and philosophers. Great patronage of the arts and sciences from the Ptolemy rulers helped raise Alexandria up, further rivalling the cultural and scientific achievements of other Greek states.
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Some of the most striking advances in early anatomy and physiology took place in Hellenistic Alexandria. Two of the most famous anatomists and physiologists of the third century were Herophilus and Erasistratus. These two physicians helped pioneer human dissection for medical research. They also conducted vivisections on the cadavers of condemned criminals, which was considered taboo until the Renaissance—Herophilus was recognized as the first person to perform systematic dissections. Herophilus became known for his anatomical works making impressing contributions to many branches of anatomy and many other aspects of medicine. Some of the works included classifying the system of the pulse, the discovery that human arteries had thicker walls than veins, and that the atria were parts of the heart. Herophilus's knowledge of the human body has provided vital input towards understanding the brain, eye, liver, reproductive organs and nervous system, and characterizing the course of disease. Erasistratus accurately described the structure of the brain, including the cavities and membranes, and made a distinction between its cerebrum and cerebellum During his study in Alexandria, Erasistratus was particularly concerned with studies of the circulatory and nervous systems. He was able to distinguish the sensory and the motor nerves in the human body and believed that air entered the lungs and heart, which was then carried throughout the body. His distinction between the arteries and veins—the arteries carrying the air through the body, while the veins carried the blood from the heart was a great anatomical discovery. Erasistratus was also responsible for naming and describing the function of the epiglottis and the valves of the heart, including the tricuspid. During the third century, Greek physicians were able to differentiate nerves from blood vessels and tendons and to realize that the nerves convey neural impulses. It was Herophilus who made the point that damage to motor nerves induced paralysis. Herophilus named the meninges and ventricles in the brain, appreciated the division between cerebellum and cerebrum and recognized that the brain was the "seat of intellect" and not a "cooling chamber" as propounded by Aristotle Herophilus is also credited with describing the optic, oculomotor, motor division of the trigeminal, facial, vestibulocochlear and hypoglossal nerves.
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Great feats were made during the third century BCE in both the digestive and reproductive systems. Herophilus was able to discover and describe not only the salivary glands, but the small intestine and liver. He showed that the uterus is a hollow organ and described the ovaries and uterine tubes. He recognized that spermatozoa were produced by the testes and was the first to identify the prostate gland.
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The anatomy of the muscles and skeleton is described in the Hippocratic Corpus, an Ancient Greek medical work written by unknown authors. Aristotle described vertebrate anatomy based on animal dissection. Praxagoras identified the difference between arteries and veins. Also in the 4th century BCE, Herophilos and Erasistratus produced more accurate anatomical descriptions based on vivisection of criminals in Alexandria during the Ptolemaic dynasty.
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In the 2nd century, Galen of Pergamum, an anatomist, clinician, writer and philosopher, wrote the final and highly influential anatomy treatise of ancient times. He compiled existing knowledge and studied anatomy through dissection of animals. He was one of the first experimental physiologists through his vivisection experiments on animals. Galen's drawings, based mostly on dog anatomy, became effectively the only anatomical textbook for the next thousand years. His work was known to Renaissance doctors only through Islamic Golden Age medicine until it was translated from the Greek some time in the 15th century. Medieval to early modern
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Anatomy developed little from classical times until the sixteenth century; as the historian Marie Boas writes, "Progress in anatomy before the sixteenth century is as mysteriously slow as its development after 1500 is startlingly rapid". Between 1275 and 1326, the anatomists Mondino de Luzzi, Alessandro Achillini and Antonio Benivieni at Bologna carried out the first systematic human dissections since ancient times. Mondino's Anatomy of 1316 was the first textbook in the medieval rediscovery of human anatomy. It describes the body in the order followed in Mondino's dissections, starting with the abdomen, then the thorax, then the head and limbs. It was the standard anatomy textbook for the next century.
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Leonardo da Vinci (1452–1519) was trained in anatomy by Andrea del Verrocchio. He made use of his anatomical knowledge in his artwork, making many sketches of skeletal structures, muscles and organs of humans and other vertebrates that he dissected.
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Andreas Vesalius (1514–1564), professor of anatomy at the University of Padua, is considered the founder of modern human anatomy. Originally from Brabant, Vesalius published the influential book De humani corporis fabrica ("the structure of the human body"), a large format book in seven volumes, in 1543. The accurate and intricately detailed illustrations, often in allegorical poses against Italianate landscapes, are thought to have been made by the artist Jan van Calcar, a pupil of Titian.
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In England, anatomy was the subject of the first public lectures given in any science; these were given by the Company of Barbers and Surgeons in the 16th century, joined in 1583 by the Lumleian lectures in surgery at the Royal College of Physicians. Late modern
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In the United States, medical schools began to be set up towards the end of the 18th century. Classes in anatomy needed a continual stream of cadavers for dissection and these were difficult to obtain. Philadelphia, Baltimore and New York were all renowned for body snatching activity as criminals raided graveyards at night, removing newly buried corpses from their coffins. A similar problem existed in Britain where demand for bodies became so great that grave-raiding and even anatomy murder were practised to obtain cadavers. Some graveyards were in consequence protected with watchtowers. The practice was halted in Britain by the Anatomy Act of 1832, while in the United States, similar legislation was enacted after the physician William S. Forbes of Jefferson Medical College was found guilty in 1882 of "complicity with resurrectionists in the despoliation of graves in Lebanon Cemetery".
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The teaching of anatomy in Britain was transformed by Sir John Struthers, Regius Professor of Anatomy at the University of Aberdeen from 1863 to 1889. He was responsible for setting up the system of three years of "pre-clinical" academic teaching in the sciences underlying medicine, including especially anatomy. This system lasted until the reform of medical training in 1993 and 2003. As well as teaching, he collected many vertebrate skeletons for his museum of comparative anatomy, published over 70 research papers, and became famous for his public dissection of the Tay Whale. From 1822 the Royal College of Surgeons regulated the teaching of anatomy in medical schools. Medical museums provided examples in comparative anatomy, and were often used in teaching. Ignaz Semmelweis investigated puerperal fever and he discovered how it was caused. He noticed that the frequently fatal fever occurred more often in mothers examined by medical students than by midwives. The students went from the dissecting room to the hospital ward and examined women in childbirth. Semmelweis showed that when the trainees washed their hands in chlorinated lime before each clinical examination, the incidence of puerperal fever among the mothers could be reduced dramatically.
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Anatomy
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Before the modern medical era, the main means for studying the internal structures of the body were dissection of the dead and inspection, palpation and auscultation of the living. It was the advent of microscopy that opened up an understanding of the building blocks that constituted living tissues. Technical advances in the development of achromatic lenses increased the resolving power of the microscope and around 1839, Matthias Jakob Schleiden and Theodor Schwann identified that cells were the fundamental unit of organization of all living things. Study of small structures involved passing light through them and the microtome was invented to provide sufficiently thin slices of tissue to examine. Staining techniques using artificial dyes were established to help distinguish between different types of tissue. Advances in the fields of histology and cytology began in the late 19th century along with advances in surgical techniques allowing for the painless and safe removal of biopsy specimens. The invention of the electron microscope brought a great advance in resolution power and allowed research into the ultrastructure of cells and the organelles and other structures within them. About the same time, in the 1950s, the use of X-ray diffraction for studying the crystal structures of proteins, nucleic acids and other biological molecules gave rise to a new field of molecular anatomy.
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Equally important advances have occurred in non-invasive techniques for examining the interior structures of the body. X-rays can be passed through the body and used in medical radiography and fluoroscopy to differentiate interior structures that have varying degrees of opaqueness. Magnetic resonance imaging, computed tomography, and ultrasound imaging have all enabled examination of internal structures in unprecedented detail to a degree far beyond the imagination of earlier generations. See also
Anatomical model
Outline of human anatomy
Plastination Notes Bibliography "Anatomy of the Human Body". 20th edition. 1918. Henry Gray External links
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Anatomy, In Our Time. BBC Radio 4. Melvyn Bragg with guests Ruth Richardson, Andrew Cunningham and Harold Ellis.
Anatomia Collection: anatomical plates 1522 to 1867 (digitized books and images)
Lyman, Henry Munson. The Book of Health (1898). Science History Institute Digital Collections .
Gunther von Hagens True Anatomy for New Ways of Teaching. Branches of biology
Morphology (biology)
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Algorithms (journal)
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Algorithms is a monthly peer-reviewed open-access scientific journal of mathematics, covering design, analysis, and experiments on algorithms. The journal is published by MDPI and was established in 2008. The founding editor-in-chief was Kazuo Iwama (Kyoto University). From May 2014 to September 2019, the editor-in-chief was Henning Fernau (Universität Trier). The current editor-in-chief is Frank Werner (Otto-von-Guericke-Universität Magdeburg). Abstracting and indexing
The journal is abstracted and indexed in:
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Algorithms (journal)
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See also
Journals with similar scope include:
ACM Transactions on Algorithms
Algorithmica
Journal of Algorithms (Elsevier) References External links Computer science journals
Open access journals
MDPI academic journals
English-language journals
Publications established in 2008
Mathematics journals
Monthly journals
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American Revolutionary War
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The American Revolutionary War (April 19, 1775 – September 3, 1783), also known as the Revolutionary War or American War of Independence, secured a United States of America independent from Great Britain. Fighting began on April 19, 1775, followed by the Declaration of Independence on July 4, 1776. The American Patriots were supported by France and Spain, conflict taking place in North America, the Caribbean, and Atlantic Ocean. It ended on September 3, 1783 when Britain accepted American independence in the Treaty of Paris, while the Treaties of Versailles resolved separate conflicts with France and Spain.
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Established by Royal charter in the 17th and 18th centuries, the American colonies were largely autonomous in domestic affairs and commercially prosperous, trading with Britain and its Caribbean colonies, as well as other European powers via their Caribbean entrepôts. After British victory in the Seven Years' War in 1763, tensions arose over trade, colonial policy in the Northwest Territory and taxation measures, including the Stamp Act and Townshend Acts. Colonial opposition led to the 1770 Boston Massacre and 1773 Boston Tea Party, with Parliament responding by imposing the so-called Intolerable Acts.
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Established on September 5, 1774, the First Continental Congress drafted a Petition to the King and organized a boycott of British goods. Despite attempts to achieve a peaceful solution, fighting began with the Battle of Lexington on April 19, 1775 and in June Congress authorized George Washington to create a Continental Army. Although the "coercion policy" advocated by the North ministry was opposed by a faction within Parliament, both sides increasingly viewed conflict as inevitable. The Olive Branch Petition sent by Congress to George III in July 1775 was rejected and in August Parliament declared the colonies to be in a state of rebellion.
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Following the loss of Boston in March 1776, Sir William Howe, the new British commander-in-chief, launched the New York and New Jersey campaign. He captured New York City in November, before Washington won small but significant victories at Trenton and Princeton, which restored Patriot confidence. In summer 1777, Howe succeeded in taking Philadelphia, but in October a separate force under John Burgoyne was forced to surrender at Saratoga. This victory was crucial in convincing powers like France and Spain an independent United States was a viable entity.
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France provided the US informal economic and military support from the beginning of the rebellion, and after Saratoga the two countries signed a commercial agreement and a Treaty of Alliance in February 1778. In return for a guarantee of independence, Congress joined France in its global war with Britain and agreed to defend the French West Indies. Spain also allied with France against Britain in the Treaty of Aranjuez (1779), though it did not formally ally with the Americans. Nevertheless, access to ports in Spanish Louisiana allowed the Patriots to import arms and supplies, while the Spanish Gulf Coast campaign deprived the Royal Navy of key bases in the south.
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This undermined the 1778 strategy devised by Howe's replacement, Sir Henry Clinton, which took the war into the Southern United States. Despite some initial success, by September 1781 Cornwallis was besieged by a Franco-American force in Yorktown. After an attempt to resupply the garrison failed, Cornwallis surrendered in October, and although the British wars with France and Spain continued for another two years, this ended fighting in North America. In April 1782, the North ministry was replaced by a new British government which accepted American independence and began negotiating the Treaty of Paris, ratified on September 3, 1783. Prelude to revolution
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The French and Indian War, part of the wider global conflict known as the Seven Years' War, ended with the 1763 Peace of Paris, which expelled France from its possessions in New France. Acquisition of territories in Atlantic Canada and West Florida, inhabited largely by French or Spanish-speaking Catholics, led the British authorities to consolidate their hold by populating them with English-speaking settlers. Preventing conflict between settlers and Native American tribes west of the Appalachian Mountains would also avoid the cost of an expensive military occupation.
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The Proclamation Line of 1763 was designed to achieve these aims by refocusing colonial expansion north into Nova Scotia and south into Florida, with the Mississippi River as the dividing line between British and Spanish possessions in the Americas. Settlement beyond the 1763 limits was tightly restricted, while claims by individual colonies west of this line were rescinded, most significantly Virginia and Massachusetts who argued their boundaries extended from the Atlantic to the Pacific.
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Ultimately the vast exchange of territory destabilized existing alliances and trade networks between settlers and Native Americans in the west, while it proved impossible to prevent encroachment beyond the Proclamation Line. With the exception of Virginia and others "deprived" of their rights in the western lands, the colonial legislatures generally agreed on the principle of boundaries but disagreed on where to set them, while many settlers resented the restrictions. Since enforcement required permanent garrisons along the frontier, it led to increasingly bitter disputes over who should pay for them. Taxation and legislation
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Although directly administered by the Crown, acting through a local Governor, the colonies were largely governed by native-born property owners. While external affairs were managed by London, colonial militia were funded locally but with the ending of the French threat in 1763, the legislatures expected less taxation, not more. At the same time, the huge debt incurred by the Seven Years' War and demands from British taxpayers for cuts in government expenditure meant Parliament expected the colonies to fund their own defense.
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The 1763 to 1765 Grenville ministry instructed the Royal Navy to stop the trade of smuggled goods and enforce customs duties levied in American ports. The most important was the 1733 Molasses Act; routinely ignored prior to 1763, it had a significant economic impact since 85% of New England rum exports were manufactured from imported molasses. These measures were followed by the Sugar Act and Stamp Act, which imposed additional taxes on the colonies to pay for defending the western frontier. In July 1765, the Whigs formed the First Rockingham ministry, which repealed the Stamp Act and reduced tax on foreign molasses to help the New England economy, but re-asserted Parliamentary authority in the Declaratory Act.
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However, this did little to end the discontent; in 1768, a riot started in Boston when the authorities seized the sloop Liberty on suspicion of smuggling. Tensions escalated further in March 1770 when British troops fired on rock-throwing civilians, killing five in what became known as the Boston Massacre. The Massacre coincided with the partial repeal of the Townshend Acts by the Tory-based North Ministry, which came to power in January 1770 and remained in office until 1781. North insisted on retaining duty on tea to enshrine Parliament's right to tax the colonies; the amount was minor, but ignored the fact it was that very principle Americans found objectionable.
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Tensions escalated following the destruction of a customs vessel in the June 1772 Gaspee Affair, then came to a head in 1773. A banking crisis led to the near-collapse of the East India Company, which dominated the British economy; to support it, Parliament passed the Tea Act, giving it a trading monopoly in the Thirteen Colonies. Since most American tea was smuggled by the Dutch, the Act was opposed by those who managed the illegal trade, while being seen as yet another attempt to impose the principle of taxation by Parliament. In December 1773, a group called the Sons of Liberty disguised as Mohawk natives dumped 342 crates of tea into Boston Harbor, an event later known as the Boston Tea Party. Parliament responded by passing the so-called Intolerable Acts, aimed specifically at Massachusetts, although many colonists and members of the Whig opposition considered them a threat to liberty in general. This led to increased sympathy for the Patriot cause locally, as well as in Parliament and the London press.
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Break with the British Crown
Over the course of the 18th century, the elected lower houses in the colonial legislatures gradually wrested power from their Royal Governors. Dominated by smaller landowners and merchants, these Assemblies now established ad hoc provincial legislatures, variously called Congresses, Conventions, and Conferences, effectively replacing Royal control. With the exception of Georgia, twelve colonies sent representatives to the First Continental Congress to agree on a unified response to the crisis. Many of the delegates feared that an all-out boycott would result in war and sent a Petition to the King calling for the repeal of the Intolerable Acts. However, after some debate, on September 17, 1774, Congress endorsed the Massachusetts Suffolk Resolves and on October 20 passed the Continental Association; based on a draft prepared by the First Virginia Convention in August, this instituted economic sanctions against Britain.
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While denying its authority over internal American affairs, a faction led by James Duane and future Loyalist Joseph Galloway insisted Congress recognize Parliament's right to regulate colonial trade. Expecting concessions by the North administration, Congress authorized the extralegal committees and conventions of the colonial legislatures to enforce the boycott; this succeeded in reducing British imports by 97% from 1774 to 1775. However, on February 9 Parliament declared Massachusetts to be in a state of rebellion and instituted a blockade of the colony. In July, the Restraining Acts limited colonial trade with the British West Indies and Britain and barred New England ships from the Newfoundland cod fisheries. The increase in tension led to a scramble for control of militia stores, which each Assembly was legally obliged to maintain for defense. On April 19, a British attempt to secure the Concord arsenal culminated in the Battles of Lexington and Concord which began the war.
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Political reactions
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After the Patriot victory at Concord, moderates in Congress led by John Dickinson drafted the Olive Branch Petition, offering to accept royal authority in return for George III mediating in the dispute. However, since it was immediately followed by the Declaration of the Causes and Necessity of Taking Up Arms, Colonial Secretary Dartmouth viewed the offer as insincere; he refused to present the petition to the king, which was therefore rejected in early September. Although constitutionally correct, since George could not oppose his own government, it disappointed those Americans who hoped he would mediate in the dispute, while the hostility of his language annoyed even Loyalist members of Congress. Combined with the Proclamation of Rebellion, issued on August 23 in response to the Battle at Bunker Hill, it ended hopes of a peaceful settlement.
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Backed by the Whigs, Parliament initially rejected the imposition of coercive measures by 170 votes, fearing an aggressive policy would simply drive the Americans towards independence. However, by the end of 1774 the collapse of British authority meant both North and George III were convinced war was inevitable. After Boston, Gage halted operations and awaited reinforcements; the Irish Parliament approved the recruitment of new regiments, while allowing Catholics to enlist for the first time. Britain also signed a series of treaties with German states to supply additional troops. Within a year it had an army of over 32,000 men in America, the largest ever sent outside Europe at the time.
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The employment of German mercenaries and Catholics against people viewed as British citizens was opposed by many in Parliament, as well as the colonial assemblies; combined with the lack of activity by Gage, it allowed the Patriots to take control of the legislatures. Support for independence was boosted by Thomas Paine's pamphlet Common Sense, which argued for American self-government, that was widely reprinted. To draft the Declaration of Independence, Congress appointed the Committee of Five, consisting of Thomas Jefferson, John Adams, Benjamin Franklin, Roger Sherman and Robert Livingston. Identifying inhabitants of the Thirteen Colonies as "one people", it simultaneously dissolved political links with Britain, while including a long list of alleged violations of "English rights" committed by George III.
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On July 2, Congress voted for independence and published the declaration on July 4, which Washington read to his troops in New York City on July 9. At this point, the Revolution ceased to be an internal dispute over trade and tax policies and became a civil war, since each state represented in Congress was engaged in a struggle with Britain, but also split between Patriots and Loyalists. Patriots generally supported independence from Britain and a new national union in Congress, while Loyalists remained faithful to British rule. Estimates of numbers vary, one suggestion being the population as a whole was split evenly between committed Patriots, committed Loyalists and those who were indifferent. Others calculate the spilt as 40% Patriot, 40% neutral, 20% Loyalist, but with considerable regional variations.
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At the onset of the war, Congress realized defeating Britain required foreign alliances and intelligence-gathering. The Committee of Secret Correspondence was formed for "the sole purpose of corresponding with our friends in Great Britain and other parts of the world". From 1775 to 1776, it shared information and built alliances through secret correspondence, as well as employing secret agents in Europe to gather intelligence, conduct undercover operations, analyze foreign publications and initiate Patriot propaganda campaigns. Paine served as secretary, while Silas Deane was instrumental in securing French aid in Paris.
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War breaks out
As the American Revolutionary War unfolded in North America, there were two principal campaign theaters within the thirteen states, and a smaller but strategically important one west of the Appalachian Mountains to the Mississippi River and north to the Great Lakes. The full-on military campaigning began in the states north of Maryland, and fighting was most frequent and severest there between 1775 and 1778. Patriots achieved several strategic victories in the South, the British lost their first army at Saratoga, and the French entered the war as an American ally.
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In the expanded Northern theater and wintering at Valley Forge, General Washington observed British operations coming out of New York at the 1778 Battle of Monmouth. He then closed off British initiatives by a series of raids that contained the British army in New York City. The same year, Spanish-supplied Virginia Colonel George Rogers Clark joined by Francophone settlers and their Indian allies conquered Western Quebec, the US Northwest Territory.
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Starting in 1779, the British initiated a southern strategy to begin at Savannah, gather Loyalist support, and reoccupy Patriot-controlled territory north to Chesapeake Bay. Initially the British were successful, and the Americans lost an entire army at the siege of Charleston, which caused a severe setback for Patriots in the region. But then British maneuvering north led to a combined American and French force cornering a second British army at Battle of Yorktown, and their surrender effectively ended the Revolutionary War. Early engagements
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On April 14, 1775, Sir Thomas Gage, Commander-in-Chief, North America since 1763 and also Governor of Massachusetts from 1774, received orders to take action against the Patriots. He decided to destroy militia ordnance stored at Concord, Massachusetts, and capture John Hancock and Samuel Adams, who were considered the principal instigators of the rebellion. The operation was to begin around midnight on April 19, in the hope of completing it before the Patriots could respond. However, Paul Revere learned of the plan and notified Captain Parker, commander of the Concord militia, who prepared to resist the attempted seizure. British troops clashed with colonial forces at Lexington and Concord, suffering around 300 casualties before withdrawing to Boston, which was then besieged by the militia.
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In May, 4,500 British reinforcements arrived under Generals William Howe, John Burgoyne, and Sir Henry Clinton. On June 17, they seized the Charlestown Peninsula at the Battle of Bunker Hill, a frontal assault in which they suffered over 1,000 casualties. Dismayed at the costly attack which had gained them little, Gage appealed to London for a larger army to suppress the revolt, but instead was replaced as commander by Howe.
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On June 14, 1775, Congress took control of Patriot forces outside Boston, and Congressional leader John Adams nominated George Washington as commander-in-chief of the new Continental Army. Washington previously commanded Virginia militia regiments in the French and Indian War, and on June 16, John Hancock officially proclaimed him "General and Commander in Chief of the army of the United Colonies." On July 3, He assumed command on July 3, preferring to fortify Dorchester Heights outside Boston rather than assaulting it. In early March 1776, Colonel Henry Knox arrived with heavy artillery acquired in the Capture of Fort Ticonderoga. Under cover of darkness, on March 5 Washington placed these on Dorchester Heights, from where they could fire on the town and British ships in Boston Harbor. Fearing another Bunker Hill, Howe evacuated the city on March 17 without further loss and sailed to Halifax, Nova Scotia, while Washington moved south to New York City.
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Beginning in August 1775, American privateers raided towns in Nova Scotia, including Saint John, Charlottetown and Yarmouth. In 1776, John Paul Jones and Jonathan Eddy attacked Canso and Fort Cumberland respectively. British officials in Quebec began negotiating with the Iroquois for their support, while the Americans urged them to maintain neutrality. Aware of Native American leanings toward the British and fearing an Anglo-Indian attack from Canada, Congress authorized an invasion of Quebec in April 1775. A second American invasion was defeated at the Battle of Quebec on December 31, and after a loose siege the Americans withdrew on May 6, 1776. A failed counter-attack at Trois-Rivières on June 8 ended American operations in Quebec.
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However, British pursuit was blocked by American ships on Lake Champlain until they were cleared on October 11 at the Battle of Valcour Island. The American troops were forced to withdraw to Fort Ticonderoga, ending the campaign. In November 1776, a Massachusetts-sponsored uprising in Nova Scotia during the Battle of Fort Cumberland was dispersed. The cumulative failures cost the Patriots support in local public opinion, and aggressive anti-Loyalist policies in the New England colonies alienated the Canadians. The Patriots made no further attempts to invade north.
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In Virginia, an attempt by Governor Lord Dunmore to seize militia stores on April 20 1775 led to an increase in tension, although conflict was avoided for the time being. This changed after the publication of Dunmore's Proclamation on November 7, 1775, promising freedom to any slaves who fled their Patriot masters and agreed to fight for the Crown. British forces were defeated at Great Bridge on December 9 and took refuge on British ships anchored near the port of Norfolk. When the Third Virginia Convention refused to disband its militia or accept martial law, Dunmore ordered the Burning of Norfolk on January 1, 1776.
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The siege of Savage's Old Fields began on November 19 in South Carolina between Loyalist and Patriot militias, and the Loyalists were subsequently driven out of the colony in the Snow Campaign. Loyalists were recruited in North Carolina to reassert British rule in the South, but they were decisively defeated in the Battle of Moore's Creek Bridge. A British expedition sent to reconquer South Carolina launched an attack on Charleston in the Battle of Sullivan's Island on June 28, 1776, but it failed and left the South under Patriot control until 1780.
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