broad_id
string | depmap_id
string | ccle_name
string | screen_id
string | upper_limit
int64 | lower_limit
float64 | slope
float64 | r2
float64 | auc
float64 | ec50
float64 | ic50
float64 | name
string | moa
string | target
string | disease.area
string | indication
string | smiles
string | phase
string | passed_str_profiling
bool | row_name
string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRD-K47832606-001-30-1 | ACH-000651 | SW620_LARGE_INTESTINE | HTS002 | 1 | 0.095764 | 11.995594 | 0.920575 | 0.478741 | 0.0372 | 0.037865 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000651 |
BRD-K47832606-001-30-1 | ACH-000361 | SKHEP1_LIVER | HTS002 | 1 | 0.139559 | 2.788441 | 0.898839 | 0.493966 | 0.033224 | 0.037361 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000361 |
BRD-K47832606-001-30-1 | ACH-000842 | SW480_LARGE_INTESTINE | HTS002 | 1 | 0.349594 | 3.491332 | 0.570399 | 0.702706 | 0.118475 | 0.16713 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000842 |
BRD-K47832606-001-30-1 | ACH-000570 | YKG1_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.356427 | 3.153204 | 0.416435 | 0.66297 | 0.062081 | 0.092218 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000570 |
BRD-K47832606-001-30-1 | ACH-000396 | J82_URINARY_TRACT | HTS002 | 1 | 0.08508 | 3.411673 | 0.729201 | 0.477253 | 0.039089 | 0.041285 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000396 |
BRD-K47832606-001-30-1 | ACH-000777 | KYSE30_OESOPHAGUS | HTS002 | 1 | 0.18366 | 3.17299 | 0.829376 | 0.533246 | 0.038935 | 0.044978 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000777 |
BRD-K47832606-001-30-1 | ACH-000096 | G401_SOFT_TISSUE | HTS002 | 1 | 0.052201 | 0.872154 | 0.717315 | 0.446601 | 0.033723 | 0.038267 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000096 |
BRD-K47832606-001-30-1 | ACH-000955 | SNU407_LARGE_INTESTINE | HTS002 | 1 | 0.186129 | 2.198605 | 0.524274 | 0.475637 | 0.019258 | 0.023801 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000955 |
BRD-K47832606-001-30-1 | ACH-000940 | AN3CA_ENDOMETRIUM | HTS002 | 1 | 0.252511 | 4.51092 | 0.731615 | 0.670587 | 0.138909 | 0.162344 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000940 |
BRD-K47832606-001-30-1 | ACH-001318 | PLCPRF5_LIVER | HTS002 | 1 | 0.205518 | 5.184124 | 0.744519 | 0.623651 | 0.100835 | 0.111676 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-001318 |
BRD-K47832606-001-30-1 | ACH-000332 | YAPC_PANCREAS | HTS002 | 1 | 0.179859 | 2.507507 | 0.797138 | 0.600922 | 0.088976 | 0.10629 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000332 |
BRD-K47832606-001-30-1 | ACH-000839 | SCABER_URINARY_TRACT | HTS002 | 1 | 0.325133 | 3.72735 | 0.692778 | 0.700831 | 0.135438 | 0.179536 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000839 |
BRD-K47832606-001-30-1 | ACH-000082 | G292CLONEA141B1_BONE | HTS002 | 1 | 0.367168 | 6.025192 | 0.543611 | 0.883591 | 1.677874 | 2.090754 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000082 |
BRD-K47832606-001-30-1 | ACH-000178 | HS766T_PANCREAS | HTS002 | 1 | 0.393137 | 4.277273 | 0.33747 | 0.650044 | 0.037127 | 0.053256 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000178 |
BRD-K47832606-001-30-1 | ACH-000421 | SW837_LARGE_INTESTINE | HTS002 | 1 | 0.367094 | 4.700463 | 0.598665 | 0.638251 | 0.039009 | 0.051711 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000421 |
BRD-K47832606-001-30-1 | ACH-000524 | KURAMOCHI_OVARY | HTS002 | 1 | 0.264131 | 4.601143 | 0.607693 | 0.551298 | 0.026929 | 0.031706 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000524 |
BRD-K47832606-001-30-1 | ACH-000469 | YH13_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.447587 | 6.199249 | 0.345843 | 0.736209 | 0.097164 | 0.139802 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000469 |
BRD-K47832606-001-30-1 | ACH-000153 | NCIH2052_PLEURA | HTS002 | 1 | 0.280612 | 4.320349 | 0.40001 | 0.665383 | 0.109571 | 0.132588 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000153 |
BRD-K47832606-001-30-1 | ACH-000805 | COLO679_SKIN | HTS002 | 1 | 0.080202 | 3.6108 | 0.839318 | 0.487612 | 0.044904 | 0.047132 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000805 |
BRD-K47832606-001-30-1 | ACH-000429 | A704_KIDNEY | HTS002 | 1 | 2.197461 | -0.256556 | 0.067269 | 1.498535 | 0.017765 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000429 |
BRD-K47832606-001-30-1 | ACH-000108 | KP3_PANCREAS | HTS002 | 1 | 0.375995 | 1.836251 | 0.645726 | 0.634925 | 0.034214 | 0.073109 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000108 |
BRD-K47832606-001-30-1 | ACH-000939 | SKUT1_SOFT_TISSUE | HTS002 | 1 | 0.065953 | 2.338007 | 0.8324 | 0.447029 | 0.031987 | 0.033982 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000939 |
BRD-K47832606-001-30-1 | ACH-000323 | 42MGBA_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.067809 | 2.639313 | 0.832857 | 0.509748 | 0.060754 | 0.064203 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000323 |
BRD-K47832606-001-30-1 | ACH-000219 | A375_SKIN | HTS002 | 1 | 0.135411 | 1.518295 | 0.849913 | 0.464452 | 0.02446 | 0.030116 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000219 |
BRD-K47832606-001-30-1 | ACH-000903 | FTC133_THYROID | HTS002 | 1 | 0.087478 | 11.690821 | 0.580958 | 0.581573 | 0.11682 | 0.118758 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000903 |
BRD-K47832606-001-30-1 | ACH-000054 | HT1080_SOFT_TISSUE | HTS002 | 1 | 0.098865 | 0.820865 | 0.792093 | 0.59965 | 0.137048 | 0.179239 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000054 |
BRD-K47832606-001-30-1 | ACH-000302 | SNU1077_ENDOMETRIUM | HTS002 | 1 | 1.717709 | -0.636006 | 0.147308 | 1.272776 | 0.021559 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000302 |
BRD-K47832606-001-30-1 | ACH-000324 | JHOC5_OVARY | HTS002 | 1 | 0.120891 | 3.389389 | 0.701923 | 0.599423 | 0.120128 | 0.13035 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000324 |
BRD-K47832606-001-30-1 | ACH-000164 | PANC1_PANCREAS | HTS002 | 1 | 0.549863 | 3.373983 | 0.302171 | 0.859341 | 0.482034 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000164 |
BRD-K47832606-001-30-1 | ACH-000549 | SNU1076_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.200571 | 1.250918 | 0.829623 | 0.525191 | 0.031235 | 0.04706 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000549 |
BRD-K47832606-001-30-1 | ACH-000650 | IGR37_SKIN | HTS002 | 1 | 0.147588 | 1.183587 | 0.856063 | 0.458067 | 0.020665 | 0.027771 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000650 |
BRD-K47832606-001-30-1 | ACH-000217 | JHH6_LIVER | HTS002 | 1 | 0.206141 | 3.673846 | 0.744263 | 0.546944 | 0.039339 | 0.045463 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000217 |
BRD-K47832606-001-30-1 | ACH-000463 | NCIH460_LUNG | HTS002 | 1 | 0.124488 | 1.701983 | 0.882231 | 0.425082 | 0.017047 | 0.020171 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000463 |
BRD-K47832606-001-30-1 | ACH-000748 | SJSA1_BONE | HTS002 | 1 | 0.244166 | 1.215026 | 0.530495 | 0.681692 | 0.16876 | 0.292942 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000748 |
BRD-K47832606-001-30-1 | ACH-000788 | A2058_SKIN | HTS002 | 1 | 0.210971 | 2.052514 | 0.887206 | 0.648488 | 0.132586 | 0.173168 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000788 |
BRD-K47832606-001-30-1 | ACH-000545 | VMCUB1_URINARY_TRACT | HTS002 | 1 | 0.166214 | 4.826391 | 0.163078 | 0.520041 | 0.037498 | 0.040773 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000545 |
BRD-K47832606-001-30-1 | ACH-000762 | YD38_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.256284 | 1.324015 | 0.803127 | 0.556108 | 0.030401 | 0.052313 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000762 |
BRD-K47832606-001-30-1 | ACH-000792 | BFTC909_KIDNEY | HTS002 | 1 | 2.267645 | -1.381171 | 0.331971 | 1.390334 | 0.011973 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000792 |
BRD-K47832606-001-30-1 | ACH-000211 | DAOY_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.213738 | 1.416704 | 0.636509 | 0.536916 | 0.032874 | 0.048732 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000211 |
BRD-K47832606-001-30-1 | ACH-000936 | EFO27_OVARY | HTS002 | 1 | 0.368438 | 1.115223 | 0.32408 | 0.819531 | 0.651094 | 2.155629 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000936 |
BRD-K47832606-001-30-1 | ACH-000882 | IGR1_SKIN | HTS002 | 1 | 0.194109 | 2.038904 | 0.749047 | 0.738268 | 0.428163 | 0.544847 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000882 |
BRD-K47832606-001-30-1 | ACH-000471 | LI7_LIVER | HTS002 | 1 | 0.128438 | 6.020343 | 0.769726 | 0.494475 | 0.035937 | 0.037753 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000471 |
BRD-K47832606-001-30-1 | ACH-000670 | SBC5_LUNG | HTS002 | 1 | 0.257755 | 2.423864 | 0.790235 | 0.682148 | 0.156768 | 0.211397 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000670 |
BRD-K47832606-001-30-1 | ACH-000048 | TOV112D_OVARY | HTS002 | 1 | 0.096126 | 2.446666 | 0.615804 | 0.507113 | 0.050333 | 0.054922 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000048 |
BRD-K47832606-001-30-1 | ACH-000259 | KELLY_AUTONOMIC_GANGLIA | HTS002 | 1 | 0.263234 | 1.456751 | 0.277043 | 0.725495 | 0.269951 | 0.450968 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000259 |
BRD-K47832606-001-30-1 | ACH-000599 | PATU8902_PANCREAS | HTS002 | 1 | 0.333732 | 1.240176 | 0.69712 | 0.740064 | 0.228446 | 0.555063 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000599 |
BRD-K47832606-001-30-1 | ACH-000716 | TT2609C02_THYROID | HTS002 | 1 | 0.126993 | 3.399312 | 0.873806 | 0.506576 | 0.041496 | 0.045231 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000716 |
BRD-K47832606-001-30-1 | ACH-000347 | QGP1_PANCREAS | HTS002 | 1 | 0.268901 | 0.616267 | 0.460362 | 0.796546 | 0.923928 | 3.23231 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000347 |
BRD-K47832606-001-30-1 | ACH-000566 | SW1710_URINARY_TRACT | HTS002 | 1 | 0.200604 | 5.794177 | 0.692317 | 0.623474 | 0.103502 | 0.113081 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000566 |
BRD-K47832606-001-30-1 | ACH-001016 | BECKER_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.233533 | 0.873144 | 0.66817 | 0.618593 | 0.080006 | 0.164497 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-001016 |
BRD-K47832606-001-30-1 | ACH-000395 | NCIH520_LUNG | HTS002 | 1 | 0.439854 | 9.894285 | 0.543081 | 0.720985 | 0.07957 | 0.098561 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000395 |
BRD-K47832606-001-30-1 | ACH-000407 | SNU685_ENDOMETRIUM | HTS002 | 1 | 0.15874 | 1.910826 | 0.716012 | 0.536525 | 0.047654 | 0.058199 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000407 |
BRD-K47832606-001-30-1 | ACH-000418 | SW1353_BONE | HTS002 | 1 | 1.007379 | -0.669691 | -0.010249 | 1.002204 | 0.008922 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000418 |
BRD-K47832606-001-30-1 | ACH-000008 | A101D_SKIN | HTS002 | 1 | 0.186219 | 2.720184 | 0.816168 | 0.589732 | 0.07504 | 0.08906 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000008 |
BRD-K47832606-001-30-1 | ACH-000191 | BHT101_THYROID | HTS002 | 1 | 0.119813 | 1.411008 | 0.677893 | 0.484247 | 0.03385 | 0.041103 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000191 |
BRD-K47832606-001-30-1 | ACH-000941 | HEC1B_ENDOMETRIUM | HTS002 | 1 | 0.651743 | 2.011097 | 0.245194 | 0.928653 | 1.382284 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000941 |
BRD-K47832606-001-30-1 | ACH-000532 | SNU61_LARGE_INTESTINE | HTS002 | 1 | 0.30433 | 3.591658 | 0.598621 | 0.53794 | 0.015878 | 0.020618 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000532 |
BRD-K47832606-001-30-1 | ACH-000316 | SNU886_LIVER | HTS002 | 1 | 0.095541 | 1.252406 | 0.702407 | 0.451362 | 0.027597 | 0.032688 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000316 |
BRD-K47832606-001-30-1 | ACH-000677 | SW1573_LUNG | HTS002 | 1 | 0.1484 | 4.29382 | 0.842191 | 0.540821 | 0.053407 | 0.057972 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000677 |
BRD-K47832606-001-30-1 | ACH-000375 | G402_SOFT_TISSUE | HTS002 | 1 | 0.124214 | 3.543731 | 0.763893 | 0.538212 | 0.059952 | 0.064983 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000375 |
BRD-K47832606-001-30-1 | ACH-000619 | PECAPJ15_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.232149 | 5.459657 | 0.570079 | 0.635068 | 0.099319 | 0.111349 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000619 |
BRD-K47832606-001-30-1 | ACH-000965 | RL952_ENDOMETRIUM | HTS002 | 1 | 0.262403 | 1.653299 | 0.465369 | 0.745529 | 0.352414 | 0.55271 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000965 |
BRD-K47832606-001-30-1 | ACH-000210 | CADOES1_BONE | HTS002 | 1 | 0.051631 | 1.411769 | 0.696779 | 0.392652 | 0.019899 | 0.021496 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000210 |
BRD-K47832606-001-30-1 | ACH-000803 | COLO668_LUNG | HTS002 | 1 | 0.091276 | 2.931445 | 0.703148 | 0.418439 | 0.020085 | 0.021514 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000803 |
BRD-K47832606-001-30-1 | ACH-000007 | LS513_LARGE_INTESTINE | HTS002 | 1 | 0.21578 | 1.6386 | 0.855326 | 0.413498 | 0.00697 | 0.00984 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000007 |
BRD-K47832606-001-30-1 | ACH-000719 | RMGI_OVARY | HTS002 | 1 | 0.381171 | 1.778517 | 0.452293 | 0.65304 | 0.043349 | 0.097244 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000719 |
BRD-K47832606-001-30-1 | ACH-000484 | VMRCRCW_KIDNEY | HTS002 | 1 | 0.26049 | 4.428236 | 0.679158 | 0.658015 | 0.112473 | 0.13281 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000484 |
BRD-K47832606-001-30-1 | ACH-000433 | CAKI1_KIDNEY | HTS002 | 1 | 0.286257 | 13.462805 | 0.661924 | 0.641571 | 0.076487 | 0.081471 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000433 |
BRD-K47832606-001-30-1 | ACH-000688 | OV7_OVARY | HTS002 | 1 | 0.180079 | 6.391357 | 0.496453 | 0.650718 | 0.160205 | 0.171798 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000688 |
BRD-K47832606-001-30-1 | ACH-000603 | BEN_LUNG | HTS002 | 1 | 0.181709 | 1.867005 | 0.838139 | 0.498983 | 0.026267 | 0.033456 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000603 |
BRD-K47832606-001-30-1 | ACH-000351 | MKN1_STOMACH | HTS002 | 1 | 0.218295 | 3.669697 | 0.700365 | 0.530925 | 0.029584 | 0.034591 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000351 |
BRD-K47832606-001-30-1 | ACH-000627 | LCLC103H_LUNG | HTS002 | 1 | 0.084261 | 2.623453 | 0.855152 | 0.504931 | 0.052672 | 0.056511 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000627 |
BRD-K47832606-001-30-1 | ACH-000916 | NCIH1573_LUNG | HTS002 | 1 | 0.233824 | 3.239133 | 0.680755 | 0.657107 | 0.129982 | 0.157911 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000916 |
BRD-K47832606-001-30-1 | ACH-000863 | DBTRG05MG_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.124298 | 1.377049 | 0.875188 | 0.443278 | 0.020813 | 0.025614 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000863 |
BRD-K47832606-001-30-1 | ACH-000732 | PECAPJ41CLONED2_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 0.142922 | 4.218996 | 0.738507 | 0.527929 | 0.047724 | 0.051688 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000732 |
BRD-K47832606-001-30-1 | ACH-000066 | HCC4006_LUNG | HTS002 | 1 | 0.380088 | 0.984118 | 0.629611 | 0.764913 | 0.258559 | 1.103253 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000066 |
BRD-K47832606-001-30-1 | ACH-000015 | NCIH1581_LUNG | HTS002 | 1 | 0.169008 | 3.800804 | 0.646386 | 0.643968 | 0.156445 | 0.17438 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000015 |
BRD-K47832606-001-30-1 | null | null | HTS002 | 1 | 0.166697 | 1.127715 | 0.779163 | 0.523011 | 0.038439 | 0.055075 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | false | ACH-000511_FAILED_STR |
BRD-K47832606-001-30-1 | ACH-000674 | NUGC4_STOMACH | HTS002 | 1 | 0.089876 | 1.17082 | 0.919637 | 0.370026 | 0.011792 | 0.013966 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000674 |
BRD-K47832606-001-30-1 | ACH-000892 | NCIH1563_LUNG | HTS002 | 1 | 0.484388 | 4.493575 | 0.505257 | 0.764737 | 0.11941 | 0.258272 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000892 |
BRD-K47832606-001-30-1 | ACH-000909 | JHUEM2_ENDOMETRIUM | HTS002 | 1 | 0.045891 | 2.669395 | 0.868007 | 0.47348 | 0.047238 | 0.048972 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000909 |
BRD-K47832606-001-30-1 | ACH-000237 | JHOM1_OVARY | HTS002 | 1 | 0.079425 | 4.06629 | 0.774483 | 0.449537 | 0.030196 | 0.031509 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000237 |
BRD-K47832606-001-30-1 | ACH-000811 | SKOV3_OVARY | HTS002 | 1 | 0.154784 | 5.952114 | 0.599156 | 0.617897 | 0.124381 | 0.132368 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000811 |
BRD-K47832606-001-30-1 | ACH-000312 | SKNBE2_AUTONOMIC_GANGLIA | HTS002 | 1 | 0.249005 | 1.762185 | 0.716968 | 0.581333 | 0.044712 | 0.06611 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000312 |
BRD-K47832606-001-30-1 | ACH-000390 | LUDLU1_LUNG | HTS002 | 1 | 0.349342 | 3.328691 | 0.571689 | 0.640911 | 0.047219 | 0.067706 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000390 |
BRD-K47832606-001-30-1 | ACH-000901 | HCC1359_LUNG | HTS002 | 1 | 0.279091 | 4.532811 | 0.43604 | 0.690516 | 0.155153 | 0.185791 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000901 |
BRD-K47832606-001-30-1 | ACH-000307 | PK1_PANCREAS | HTS002 | 1 | 0.250309 | 2.092024 | 0.669627 | 0.617044 | 0.070338 | 0.098026 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000307 |
BRD-K47832606-001-30-1 | ACH-000289 | SNU466_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.515017 | 3.078433 | 0.168508 | 0.79189 | 0.155438 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000289 |
BRD-K47832606-001-30-1 | ACH-000309 | SKLU1_LUNG | HTS002 | 1 | 0.167707 | 4.552436 | 0.672069 | 0.383984 | 0.007598 | 0.008312 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000309 |
BRD-K47832606-001-30-1 | ACH-000733 | NCIH1838_LUNG | HTS002 | 1 | 0.586161 | 3.239677 | 0.238284 | 0.810524 | 0.117607 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000733 |
BRD-K47832606-001-30-1 | ACH-000268 | SNU245_BILIARY_TRACT | HTS002 | 1 | 1.457967 | -7.06041 | 0.343663 | 1.142766 | 0.012571 | null | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000268 |
BRD-K47832606-001-30-1 | ACH-000693 | KYSE180_OESOPHAGUS | HTS002 | 1 | 0.151525 | 1.631769 | 0.786199 | 0.60043 | 0.10361 | 0.129269 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000693 |
BRD-K47832606-001-30-1 | ACH-000684 | KMRC1_KIDNEY | HTS002 | 1 | 0.157432 | 5.559176 | 0.744989 | 0.545881 | 0.053524 | 0.057292 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000684 |
BRD-K47832606-001-30-1 | ACH-000264 | CALU6_LUNG | HTS002 | 1 | 0.195785 | 1.627558 | 0.757234 | 0.535106 | 0.036597 | 0.049663 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000264 |
BRD-K47832606-001-30-1 | ACH-000027 | GOS3_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 0.483057 | 4.786546 | 0.382921 | 0.778718 | 0.157027 | 0.31848 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000027 |
BRD-K47832606-001-30-1 | ACH-000671 | HUH6_LIVER | HTS002 | 1 | 0.371411 | 1.09936 | 0.321363 | 0.644222 | 0.0409 | 0.140666 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000671 |
BRD-K47832606-001-30-1 | ACH-000205 | PK59_PANCREAS | HTS002 | 1 | 0.245506 | 2.701464 | 0.613617 | 0.615295 | 0.070978 | 0.091137 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000205 |
BRD-K47832606-001-30-1 | ACH-000720 | TCCSUP_URINARY_TRACT | HTS002 | 1 | 0.313969 | 4.692221 | 0.579244 | 0.603471 | 0.036647 | 0.045243 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000720 |
BRD-K47832606-001-30-1 | ACH-000814 | HS939T_SKIN | HTS002 | 1 | 0.169726 | 1.800003 | 0.872752 | 0.510948 | 0.032917 | 0.041445 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000814 |
BRD-K47832606-001-30-1 | ACH-000885 | TOV21G_OVARY | HTS002 | 1 | 0.089432 | 1.668931 | 0.730144 | 0.496091 | 0.046513 | 0.052343 | floxuridine | DNA synthesis inhibitor | TYMS | oncology | colorectal cancer | OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O | Launched | true | ACH-000885 |
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