id
int64 12
273M
| source
stringclasses 1
value | version
stringclasses 1
value | added
stringdate 1994-05-03 07:51:01
2024-10-01 06:17:39
| created
stringdate 1-01-01 00:00:00
2025-01-01 00:00:00
| title
stringlengths 5
300
| abstract
stringlengths 183
10k
| sha1
stringlengths 40
40
| sources
stringlengths 3
196
| s2fieldsofstudy
stringlengths 3
293
⌀ | extfieldsofstudy
stringlengths 3
143
⌀ | external_ids
stringlengths 8
114
⌀ |
|---|---|---|---|---|---|---|---|---|---|---|---|
9,928,455 | pes2o/s2ag | v3-fos-license | 2018-04-03T00:17:14.727Z | 2000-01-01T00:00:00.000 | Perceived Social Support from Parents and Peers: Which Is the Stronger Predictor of Adolescent Substance Use? | A number of factors influence adolescent substance use. The main goal of this study has been to investigate how sociodemographics, psychosocial health, and perceived support from parents and friends might predict smoking, drinking, and drug use in adolescence. Data were collected using self-administered questionnaires among secondary school students (n = 1,039) in Szeged, Hungary. Sociodemographics (gender, age, and the type of school) proved to be the key predictors of substance use. While neither friend nor mother support appeared to be strong predictors, a low level of perceived father support increased the chance of all types of substance use. | e3c2a16e4afb2928e5b749e8cc3a62fe8d1bab60 | Unpaywall, MAG, MergedPDFExtraction, Medline, TaylorAndFrancis | Psychology, Sociology | Psychology, Medicine | DOI:10.3109/10826080009147475, MAG:2137768587 |
16,000,406 | pes2o/s2ag | v3-fos-license | 2017-02-24T20:14:33.620Z | 2012-11-01T00:00:00.000 | Shape optimization of planar antennas using Level Set Method | The inverse scattering problem of finding the optimal shape of 2D or 3D metallic or dielectric objects has received a growing attention in the last decade using different strategies either deterministic or stochastic approaches. Here we describe the development of an inverse scattering method based on a surface integral formulation of the EM problem for finding the solution of an inverse scattering problem, which is the optimal shape of planar antennas illuminated by plane waves or dipoles from the minimization of a functional involving the desired imposed constraints (e.g. an ideal radiation pattern known at a single frequency or for a wide frequency band). The state problem is solved numerically using a moment method (or variational principle) with triangular meshes. Many inverse scattering algorithms based on gradient methods are using forward and adjoint problems for calculating the cost function derivative. Here, in order to avoid the use of an adjoint problem and to deal with a more general method, we are calculating directly the derivative of the cost functional. In this way, we have directly access to the sensitivity of the cost functional versus parameters we are interested in. After calculating the shape derivative of the cost functional, we develop an optimization procedure according to the Level Set method. This method based on an implicit representation of the antenna boundary and the speed allows reconstructing a new planar triangular mesh structure at each iteration to decrease the value of the cost functional and performing possible several topological changes. A quasi-Newton method for optimizing the parameters of specific geometries has ben also developed and applied to the design of a 2D period structure such as a Frequency Selective Surface (FSS). | d98b807eeeffe235ffc0419634b5888e68c837bd | Unpaywall, MAG, ScienceParseMerged, IEEE, Grobid | Engineering, Physics | Mathematics | DOI:10.1109/ICWITS.2012.6417692, MAG:2015912695 |
55,509,806 | pes2o/s2ag | v3-fos-license | 2018-12-11T09:07:05.408Z | 2015-04-03T00:00:00.000 | Police Sexual Misconduct: Arrested Officers and Their Victims | Abstract Police sexual misconduct encompasses a range of acts from less serious noncriminal behaviors to more egregious criminal behaviors including police sexual violence. Victims of sex crimes are often reluctant to report sexual abuse when the offender is a police officer. The study provides empirical data on 771 sex-related arrest cases from 2005 to 2008 of 555 sworn officers at 449 nonfederal law enforcement agencies across the United States. The study identifies and describes incidents where officers were arrested for sex crimes through a quantitative content analysis of published newspaper articles and court records. Findings focus on arrested officers and their victims. | 01b68cf2413a6dd361aef9e7c3edbe7d0e0948c8 | TaylorAndFrancis, Anansi, MergedPDFExtraction, ScienceParseMerged, Unpaywall, MAG | Law, Sociology | Psychology | DOI:10.1080/15564886.2014.939798, MAG:2148898677 |
226,028,057 | pes2o/s2ag | v3-fos-license | 2020-06-25T09:07:36.891Z | 2020-03-30T00:00:00.000 | Volume determination of weights in the range from 1 g to 5 kg: a comparison of hydrostatic weighing and double-weighing in air using Monte-Carlo simulation | We have investigated the two methods, double-weighing in air and hydrostatic weighing, for the determination of the volume of weights in the range from 5 kg down to 1 g. We present the mathematical equations of both methods and show that Monte-Carlo simulation is a suitable way to determine the measurement uncertainties and overcome the difficulties in dealing with correlated variables. We found that the measurement uncertainties of the two methods are comparable and that double-weighing in air is an efficient method for determining the volume of weights below 1 kg. | c24a025c4cb704e7ebcdd27aa25662e885560738 | Crossref, Unpaywall, MAG | Physics, Engineering | Materials Science | DOI:10.21014/acta_imeko.v9i1.715, MAG:3036822634 |
18,170,307 | pes2o/s2ag | v3-fos-license | 2017-04-27T08:19:21.350Z | 2003-09-01T00:00:00.000 | Histological evaluation of chondral defects after autologous chondrocyte implantation of the knee. | We have performed a prospective, single-surgeon study analysing the histological results of autologous chondrocyte implantation. Fourteen patients underwent autologous chondrocyte implantation of the knee and were evaluated at one year by clinical assessment and arthroscopy. Standard staining was used to examine the sections. In addition, in situ hybridisation was used to establish type-IIa and type-IIb collagen mRNA expression and immunolocalisation techniques demonstrated the positions of type-II and type-X collagen. Eight patients regenerated hyaline cartilage and also contained type-X collagen in the deepest layers and type-II collagen in the deep layers. Three demonstrated fibrocartilage and had type-I collagen in the deep layers. In situ hybridisation revealed that all 14 samples had the potential to express both type-IIa and type-IIb collagen. We have shown that one year after the initial implantation chondrocytes are capable of producing type-II collagen and that they continue to proliferate and mature. | 062c84a5436569cd1c81ac9a29c7c7737cbe3408 | Medline, Anansi, Grobid, ScienceParseMerged, MAG, Unpaywall | Medicine | Medicine | DOI:10.1302/0301-620X.85B7.13672, MAG:2165593288 |
1,129,959 | pes2o/s2ag | v3-fos-license | 2018-04-03T03:10:56.952Z | 1993-07-01T00:00:00.000 | Evaluating chest pain in the emergency department. | Chest pain is one of the most difficult diagnostic problems for physicians working in an emergency department. In this setting, more malpractice dollars are awarded for missed myocardial infarction than for any other physician error. This problem usually occurs when the patient has atypical symptoms, the physician is inexperienced, or the diagnosis is not considered. The clinical manifestations of myocardial infarction vary greatly, and patients with "atypical" presentations have a poorer prognosis than those with classic symptoms. Although no feature of a patient's history excludes infarction with certainty, pain that is sharp, positional, pleuritic, or reproduced by palpation indicates a lower probability of acute ischemic heart disease. New immunochemical methods and serial sampling strategies have increased the sensitivity of creatine kinase-MB as an indicator for the disorder. Recent investigations have also established the prognostic value of the initial electrocardiogram. These methods allow emergency physicians to assess the risk of complications and to perform triage when there is a shortage of beds in the coronary care unit. Emergency physicians must also consider other diseases for which coronary care might be beneficial. | d18e0fe70006708a7983491a6b6cfd20b58cedec | Adhoc, Medline, MergedPDFExtraction, ScienceParsePlus, MAG | Medicine | Medicine | MAG:39297380 |
45,292,109 | pes2o/s2ag | v3-fos-license | 2018-04-03T06:01:30.127Z | 2011-08-01T00:00:00.000 | Estimation of the postmortem interval by means of 1H MRS of decomposing brain tissue: influence of ambient temperature | Standard methods for the estimation of the postmortem interval (PMI, time since death), based on the cooling of the corpse, are limited to about 48 h after death. As an alternative, noninvasive postmortem observation of alterations of brain metabolites by means of 1H MRS has been suggested for an estimation of the PMI at room temperature, so far without including the effect of other ambient temperatures. In order to study the temperature effect, localized 1H MRS was used to follow brain decomposition in a sheep brain model at four different temperatures between 4 and 26°C with repeated measurements up to 2100 h postmortem. The simultaneous determination of 25 different biochemical compounds at each measurement allowed the time courses of concentration changes to be followed. A sudden and almost simultaneous change of the concentrations of seven compounds was observed after a time span that decreased exponentially from 700 h at 4°C to 30 h at 26°C ambient temperature. As this represents, most probably, the onset of highly variable bacterial decomposition, and thus defines the upper limit for a reliable PMI estimation, data were analyzed only up to this start of bacterial decomposition. As 13 compounds showed unequivocal, reproducible concentration changes during this period while eight showed a linear increase with a slope that was unambiguously related to ambient temperature. Therefore, a single analytical function with PMI and temperature as variables can describe the time courses of metabolite concentrations. Using the inverse of this function, metabolite concentrations determined from a single MR spectrum can be used, together with known ambient temperatures, to calculate the PMI of a corpse. It is concluded that the effect of ambient temperature can be reliably included in the PMI determination by 1H MRS. Copyright © 2011 John Wiley & Sons, Ltd. | d698fc8b04f7f38b852e6d64af684efdbe7d6b0d | MAG, Medline, Wiley, Unpaywall, MergedPDFExtraction | Medicine, Environmental Science | Chemistry, Medicine | DOI:10.1002/nbm.1623, MAG:2142707085 |
140,158,809 | pes2o/s2ag | v3-fos-license | 2019-04-24T13:06:17.792Z | 1995-01-01T00:00:00.000 | A 1200 year record of accumulation from northern Greenland | We present the first detailed study of regional and secular changes in accumulation rate from northern Greenland. Four 100–150 m ice cores from this previously little investigated region have been dielectrically profiled and a good chronology for all four ice cores established by modelling the density profiles and identifying volcanic peaks in the records. This made it possible to calculate the accumulation rates of each core. The current accumulation rates show that there is a large region of low accumulation rate to the northeast of central Greenland with drops in accumulation rate of 25% 150 km, and 50% 300 km from Summit. Relatively large variations in accumulation rate over time are seen in all the cores. We have compared the resulting accumulation-rate record, which should be related to changes in local air temperature over northern Greenland, with Scandinavian tree-ring records and have interpreted the data as showing an early Medieval Warm Epoch, but no pronounced “Little Ice Age” and no unequivocal greenhouse warming effect as yet in northern Greenland. | 7534d8ddd7f28a2b5e0a464289021e43bd6b9ac4 | Cambridge, Unpaywall, MergedPDFExtraction, MAG | Environmental Science, Geology | Geology | DOI:10.3189/S0260305500015548, MAG:1645486303 |
260,941,665 | pes2o/s2ag | v3-fos-license | 2023-08-17T15:03:12.277Z | 2023-08-15T00:00:00.000 | Dynamic Analysis of the Carbon Footprint in Winter Wheat Production Based on Lifecycle Assessment and the LMDI Model: A Case Study of Jiangsu Province in China | This study applies the lifecycle assessment (LCA) to quantify the carbon footprint within the winter wheat production system in Jiangsu Province during 2011–2020. Additionally, the study employs the Logarithmic Mean Division Index (LMDI) to analyze the driving factors behind its changes. The results show that (1) the greenhouse gas emissions from wheat production in the region increased from 4837.8 kgCO2-eq/hm2 to 5701.1 kgCO2-eq/hm2 with an annual average increase of 95.9 kgCO2-eq/hm2; (2) the primary carbon sequestration method for wheat production in Jiangsu Province is straw returning; (3) the carbon footprint of wheat at yield scale and value scale generally increased during the period, whereas the carbon footprint at cost scale decreased over the years; (4) the driving factors effects’ cumulative contribution rates are as follows: economic level > population size > employment structure > production structure > production efficiency. This research explores the dynamic changes and driving factors influencing the carbon footprint associated with winter wheat production in Jiangsu Province, which could provide theoretical references for the future clean production of winter wheat. | c6479efd5540512c9857614a28674efd3012505e | Crossref | Environmental Science, Agricultural and Food Sciences | null | DOI:10.3390/su151612396 |
204,911,406 | pes2o/s2ag | v3-fos-license | 2019-10-26T18:39:55.964Z | 2016-03-31T00:00:00.000 | A Critical Assessment of the Swarnajayanti Gram Swarojagar Yojana in India | The present study is a critical assessment of Swarnajayanti Gram Swarojagar Yojana (SGSY), a national level anti-poverty program of the government of India with regard to poverty eradication and women's empowerment. Though the SGSY scheme focuses only on poverty reduction and does not have explicit gender equality objectives, however, number of women members and women Self-help groups are encouraged to be linked with this program than men. The Ministry of Rural Development, Government of India, constituted a committee on credit-related issues under SGSY to analyze the constraints in the adequate flow of credit to Self-help groups of SGSY and to suggest measures and strategies for promoting effective credit linkages to the SHGs and made two strategies of universalization coverage of SHGs assisted by bank credit and providing skills at least to one youth of a Below Poverty Line (BPL) family necessitates restructuring of SGSY. | a1b0f93b1a8a597be7a0a21a6d8adc8fe29baa1a | MergedPDFExtraction, ScienceParsePlus, ScienceParseMerged, Neliti, Anansi | Economics, Sociology | null | null |
256,648,706 | pes2o/s2ag | v3-fos-license | 2023-02-08T16:04:14.369Z | 2023-01-01T00:00:00.000 | The quality of professional practices in infection control programs in Brazil: a cross-sectional study | ABSTRACT Objective To analyze the quality of professional practices in infection control programs regarding structure, process, and outcome. Method This is a quantitative, descriptive, and cross-sectional study carried out in 114 hospital infection control services in the five official regions of Brazil. The data were collected using a structured instrument whose psychometric properties were previously validated. Data treatment was performed by principal component analysis and non-parametric Kruskal-Wallis test. Results The best quality index of infection control programs was attributed to the South region, to hospitals that had 300 beds or more, to those that used the National Healthcare Safety Network criterion for infection surveillance and to places that carried out an active prospective search as their surveillance method. Conclusion and implications for practice: The quality of infection control programs is related to hospital location, size, and infection surveillance method. The creation of a quality index, hitherto unheard of in Brazilian studies, draws attention to the precarious performance of health services. | 4d5f1bdcaf33fb0dbde0a831b2a9d198ac0bf72a | Crossref | Medicine | null | DOI:10.1590/2177-9465-ean-2022-0229en |
19,874,257 | pes2o/s2ag | v3-fos-license | 2017-06-17T18:55:23.707Z | 2006-01-15T00:00:00.000 | Effect of a targeted obstructive sleep apnea consult to improve access and quality at a sleep disorders center. | STUDY OBJECTIVES
We sought to evaluate whether a targeted obstructive sleep apnea (OSA) consult (TOSAC) protocol that reduced sleep-specialist time spent with patients suspected of having OSA would improve quality of care compared with the previous clinical method for evaluation of patients internally referred for suspected OSA.
METHODS
Prospective cohort design. TOSAC patients received oximetry and criteria screening prior to a split-night polysomnography and a 45-minute sleep-specialist consult, while control patients received consult, testing, and a follow-up visit (90 minutes of sleep-specialist time).
RESULTS
We enrolled 186 TOSAC and 94 control patients. TOSAC patients completed their evaluation in a median of 7.0 days compared with 60.0 days for the controls (p < .001). At baseline, the TOSAC group was sleepier (Epworth Sleepiness Scale 13.9+/-4.5 vs 11.0+/-4.3; p < .001) and had a slightly lower quality of life (Functional Outcomes of Sleep Questionnaire 15.0+/-3.0 vs 16.8+/-2.2, p < .001) than controls. The apnea-hypopnea index noted at polysomnography was similar in TOSAC and control patients (28.6+/-29.5 vs 23.1+/-23.9, p = .156), and the prevalence of OSA was similar in both groups (75% vs 72%, p = .616). At 1 month of therapy, improvement in the Epworth Sleepiness Scale and overall patient satisfaction were similar between groups (all p > .10), while TOSAC patients had a slightly greater improvement on the Functional Outcomes of Sleep Questionnaire (p = .010). TOSAC patients reported better subjective continuous positive airway pressure compliance (median 42.0 vs 32.5 hours/week; p = .037).
CONCLUSIONS
A protocol-driven evaluation pathway for OSA that used screening with oximetry and less sleep-specialist time shortened access and produced similar diagnoses, improvements in sleepiness and quality of life, and overall satisfaction. | e7bda40ac7dff8dab0b4ba5274895713b01eead5 | MAG, Unpaywall, Anansi, ScienceParseMerged, Medline | Medicine | Medicine | DOI:10.5664/JCSM.26435, MAG:2182131521 |
26,124,278 | pes2o/s2ag | v3-fos-license | 2018-04-03T06:05:10.812Z | 2003-03-01T00:00:00.000 | Web-Based Programs for the Display and Analysis of Transmembrane α-Helices in Aligned Protein Sequences | We developed novel programs for displaying and analyzing the transmembrane α-helical segments (TMSs) in the aligned sequences of homologous integral membrane proteins. TMS_ALIGN predicts the positions of putative TMSs in multiply aligned protein sequences and graphically shows the TMSs in the alignment. TMS_SPLIT (1) predicts the positions of TMSs for each sequence; (2) allows a user to select proteins with a specified number of TMSs, and (3) splits the sequences into groups of TMSs of equal numbers. TMS_CUT works like TMS_SPLIT, but it can cut sequences with any combination of TMSs. The BASS program similarly allows comparison of protein repeat elements, equivalent to TMS_SPLIT plus IC, but it provides the comparison data expressed in BLAST E values. These programs, together with the IntraCompare program, facilitate the identification of repeat sequences in integral membrane proteins. They also facilitate the estimation of protein topology and the determination of evolutionary pathways. | e9ba48d048510f15465d34d01f321df15e6b44f4 | MAG, MergedPDFExtraction, Unpaywall, Karger, ScienceParsePlus, Medline, ScienceParseMerged | Biology | Biology, Medicine | DOI:10.1159/000068718, MAG:2070751160 |
126,032,642 | pes2o/s2ag | v3-fos-license | 2019-04-22T13:03:27.316Z | 2016-06-01T00:00:00.000 | On the units radian and cycle for the quantity plane angle | This paper is concerned with the names and symbols for quantities used to describe oscillatory motion such as for a harmonic oscillator, and the units to be used for the quantity plane angle and phase angle for an oscillator, and related quantities. I draw attention to the need to carefully distinguish the names and symbols for quantities from the names and symbols for their numerical values in any application, and the significance of including units such as radian and cycle for the quantity plane angle. The familiar equations for a harmonic oscillator such as ω = 2πν, and the relation ħ = h/2π for the Planck constant, are shown to hold only if the symbols are taken to represent the dimensionless numerical values of the quantities concerned in particular units, rather than the actual values which are not dimensionless as generally used in the equations of physics. Alternative ways of handling these quantities and units are discussed. | 626a52ed0ad2df3ef60ed7257081f0ccab779155 | MAG, ScienceParsePlus, Unpaywall, IOP, MergedPDFExtraction | Physics | Mathematics | DOI:10.1088/0026-1394/53/3/991, MAG:2529197370 |
210,493,062 | pes2o/s2ag | v3-fos-license | 2019-11-22T01:31:35.045Z | 2020-10-01T00:00:00.000 | “It’d Just Be Banter”: Sectarianism in a Northern Irish Rugby Club | Nearly two decades after the Good Friday Agreement, sectarianism still functions to structure much of the Northern Irish society. While this is often considered in terms of high-profile cases of sectarian violence, most sectarian behavior occurs in everyday practices. This article explores how sectarianism is expressed and understood within the context of a Northern Irish rugby club. I conducted a season-long ethnography using participant observation, focus group discussions, and semistructured interviews to gain an understanding of the particular context which framed the sectarian discourses at the club. Rather than a purely oppressive model, Ballycross RFC showcased how the sectarian climate of the Northern Irish society can be used and experienced in a multitude of ways. | 2788903b2fee9758277a759d95cb6d82c38b395f | Sage, Unpaywall, Crossref, MAG | Sociology | History | DOI:10.1177/1532708619886330, MAG:2985156908 |
15,671,040 | pes2o/s2ag | v3-fos-license | 2017-02-16T15:48:50.211Z | 2015-10-01T00:00:00.000 | Finger Vein verification using local histogram of hybrid texture descriptors | Lately, finger vein has been recognized as an efficacious biometric method for user authentication due to the uniqueness of vein patterns and its insusceptibility to forgery because the vein patterns reside inside the human body. In this work, hybrid histogram descriptor is the proposed method. This method utilizes the sign and magnitude components of the texture extracted by using Binary Gradient Contour (BGC). Subsequently, the histogram is locally computed to determine the weight distribution of the sign and magnitude value for the hybrid texture descriptors. The extensive experimental results demonstrate the overall superiority of the proposed method with the EER as low as 0.353%. | 3c1f234ead69826e5ca5f11a5f0bf6a3a00d078a | DBLP, Grobid, IEEE, ScienceParseMerged, Unpaywall, MAG | Computer Science | Computer Science | DOI:10.1109/ICSIPA.2015.7412209, MAG:2292764212 |
18,995,538 | pes2o/s2ag | v3-fos-license | 2014-10-01T00:00:00.000Z | 2004-01-01T00:00:00.000 | 0 Fe b 20 04 Chandra Observations of X-Ray Weak Narrow-Line Seyfert 1 Galaxies | We present Chandra observations of 17 optically-selected, X-ray weak narrow-line Seyfert 1 (NLS1) galaxies. These objects were optically identified by Williams et al. (2002) in the Sloan Digital Sky Survey Early Data Release, but were not found in the ROSAT All-Sky Survey (RASS) despite having optical properties similar to RASS– detected NLS1s. All objects in this sample were detected by Chandra and exhibit a range of 0.5–2 keV photon indices Γ = 1.1 − 3.4. One object was not detected in the soft band, but has a best–fit Γ = 0.25 over the full 0.5–8 keV range. These photon indices extend to values far below what are normally observed in NLS1s. A composite X-ray spectrum of the hardest objects in this sample does not show any signs of absorption, although the data do not prohibit one or two of the objects from being highly absorbed. We also find a strong correlation between Γ and L 1keV ; this may be due to differences in L bol /L Edd among the NLS1s in this sample. Such variations are seemingly in conflict with the current paradigm that NLS1s accrete near the Eddington limit. Most importantly, this sample shows that strong, ultrasoft X-ray emission is not a universal characteristic of NLS1s; in fact, a substantial number may exhibit weak and/or low–Γ X-ray emission. | 54152ec0ad4ba87bd68c28065468423c1d2b13c1 | Grobid, ScienceParseMerged, CiteSeerX | Physics | null | null |
42,191,489 | pes2o/s2ag | v3-fos-license | 2017-08-27T12:17:59.041Z | 2007-01-01T00:00:00.000 | Karyotypic characterization of two species of the genus Serrapinnus (Characiformes, Characidae), with the description of a structural polymorphism in S. heterodon | Abstract The family Characidae, one of the largest and more diversified fish families in the Neotropical region, is certainly not a monophyletic group, which is supported by the cytogenetic data showing its extensive chromosome variability. In this work, two species of the genus Serrapinnus, S. heterodon and S. piaba, from the São Francisco river basin were analyzed. Both species presented the same diploid number, 2n=52 chromosomes, and the same karyotypic formula, 16m+20sm+14st+2a. The heterochromatin distribution, evidenced by C-banding, was also similar between both species. On the other hand, two NORs were evidenced in S. heterodon, while a multiple NOR system was characterized in S. piaba, both confirmed by silver nitrate staining as well as by fluorescent in situ hybridization with 18S rDNA probe. Furthermore, two additional karyotypes (cytotypes) were observed in S. heterodon, with 15m+20sm+14st+3a and 17m+20sm+14st+la chromosomes, respectively, characterizing a structural chromosome polymorphism in the population. The differences between the three S. heterodon, karyotypic forms are probably due to pericentric inversions related to the 8th and 26th chromosome pairs. | c97cec716e6895db396926fd8f3130314af6544f | MAG, Anansi, ScienceParseMerged, TaylorAndFrancis, MergedPDFExtraction, Unpaywall | Biology | Biology | DOI:10.1080/00087114.2007.10797954, MAG:2157938633 |
46,766,532 | pes2o/s2ag | v3-fos-license | 2017-09-29T08:40:24.495Z | 2015-06-17T00:00:00.000 | When a ban really is not a ban: internet loopholes and Djarum flavoured cigarettes in the USA | Bans on flavoured cigarettes have been enacted in the USA,1 the EU2 and elsewhere. However, little is known about industry and consumer counter reactions. Djarum, which controls 97% of flavoured cigarette sales in the USA, immediately released ‘cigars’ resembling their banned counterparts and continued to manufacturer flavoured cigarettes.3 This study describes: (A) online consumer interest4 in, and (B) promotion and availability of Djarum cigarettes, and their cigar replacements, before and after the USA banned flavoured cigarettes in 2009.
Google searches originating in the USA including ‘Djarum’ in combination with ‘cigarette/s’ versus ‘Djarum’ in combination with ‘cigar/s’ (eg, ‘Djarum cigarettes’ would be pooled in the cigarette trend) were monitored (google.com/trends), then regressed on time (eg, 2008–2014).
The top 50 Google search results between 29 August 2013 and 28 November 2014 for ‘Djarum cigars’ and ‘Djarum cigarettes’ were classified as websites that described Djarum cigarettes or cigars favourably (promotion), and as websites that sold either product (retailing). Two investigators classified the results (κ=0.88).
Djarum cigarette searches … | e1598357da1ee8f0d6d1319434f5e2e0cfa6029c | MergedPDFExtraction, MAG, Medline, Unpaywall, ScienceParsePlus, Anansi, ScienceParseMerged, BMJ, Highwire | Business | Business, Medicine | DOI:10.1136/tobaccocontrol-2015-052309, MAG:2259285097 |
258,981,695 | pes2o/s2ag | v3-fos-license | 2023-05-31T15:12:55.510Z | 2023-05-01T00:00:00.000 | 0347 CBT-I Leads to Changes in Actigraphy and Sleep Diary-Assessed Sleep Parameters in Veterans with Psychosis and Insomnia |
Up to 80% of people with psychosis have insomnia. While insomnia worsens psychotic symptoms and functioning, treating insomnia may improve functioning and recovery. Cognitive Behavioral Therapy for Insomnia (CBT-I) is an effective treatment, but there is limited research on CBT-I in people living with psychosis. We developed guidelines and materials for conducting CBT-I with people with psychosis and evaluated actigraphy and sleep diary-measured outcomes in Veterans who participated in an RCT of CBT-I for psychosis.
Forty-seven Veterans with insomnia and psychosis were randomized to either CBT-I using novel psychosis-specific guidelines and materials (n=26) or to an active treatment control, the Health and Wellness (HW) intervention (n=21). Participants completed both actigraphy and daily sleep logs for two weeks at baseline, post-treatment, and 3-month follow-up.
Using a mixed effects model for repeated measures, mean change from baseline at post and follow-up was compared for CBT-I for psychosis and HW. For actigraphy-measured total sleep time (TST) and time in bed (TIB), and diary-measured TIB, there was a significant decrease in these parameters for the CBT-I group relative to an increase for HW at post (t(1082)=-2.41, p=.016, d=-.38; t(1082)=-2.19, p=.029, d=-.44; t(1318)=-3.19, p=.002, d =-.70, respectively) and in diary-measured TIB at follow-up (t(1318)=-1.97, p=.049, d=-.37. Sleep diary-measured sleep efficiency (SE) increased significantly more in CBT-I than in HW (t(1266)=1.99, p=.047, d=.54) at post. There were no group differences in actigraphy-measured SE, sleep onset latency (SOL), or WASO, or sleep diary-measured TST, SOL, WASO, or number of awakenings at post. There were no other group differences for actigraphy- or diary-measured sleep variables at follow-up, though underpowered due to sample size at the follow-up timepoint.
Results indicate that CBT-I tailored to the needs of people with psychosis can change several actigraphy- and diary-assessed common sleep variables of interest--TST, TIB, and SE. CBT-I for psychosis should be further investigated with a larger randomized controlled trial over a longer time period.
Time supported by U.S. Department of Veterans Affairs, RR&D-1IK2RX001836, PI: Elizabeth A. Klingaman.
| 052341454f5e5cb197087d52aae00362e30318ff | Crossref | Psychology, Medicine | null | DOI:10.1093/sleep/zsad077.0347 |
250,291,045 | pes2o/s2ag | v3-fos-license | 2022-07-06T15:17:54.536Z | 2022-07-04T00:00:00.000 | Therapeutic Potential of Ajwa Dates (Phoenix dactylifera) Extract in Prevention of Benzo(a)pyrene-Induced Lung Injury through the Modulation of Oxidative Stress, Inflammation, and Cell Signalling Molecules | Chronic respiratory diseases are a leading cause of lung-related death worldwide. The vital factors causing lung pathogenesis include consistent exposure to tobacco smoke, air pollution, and occupational risks. Regarding the significant morbidity and mortality linked to lung pathogenesis, there are neither conclusive treatments nor wholly preventive strategies. In the present study, the protective mechanism of Ajwa date extract (ADE), on Benzopyrene [B(a)P]-induced lung injury in animal models was investigated using antioxidant, lipid peroxidation, anti-inflammatory activities, angiogenesis, histopathological studies, and apoptosis assays. B(a)P treatment significantly decreased the level of antioxidant enzymes such as catalase (Cat) (13.4 vs. 24.7 U/mg protein), Superoxide dismutase (SOD) (38.5 vs. 65.7 U/mg protein), Glutathione peroxidase (GPx) (42.4 vs. 57.3 U/mg protein) and total antioxidant capacity (TAC) (49.8 vs. 98.7 nM) as compared to the treatment group (p < 0.05). B(a)P treatment led to increased expression of pro-inflammatory markers such as TNF-α (88.5 vs. 72.6 pg/mL), IFN-γ (4.86 vs. 3.56 pg/mL), interleukin-6 (IL-6) (109.6 vs. 85.4 pg/mL) and CRP (1.84 vs. 0.94 ng/mL) as compared to the treatment group (p < 0.05). The data shows a significant increase in lipid peroxidation and angiogenesis factors such as vascular endothelial growth factor (VEGF) by B(a)P treatment (p < 0.05). However, ADE treatment showed an improvement of these factors. In addition, ADE treatment significantly ameliorated histopathological changes, collagen fiber deposition, and expression pattern of VEGF and Bax proteins. Furthermore, the flow cytometry data demonstrated that B(a)P intoxication enhanced the apoptosis ratio, which was significantly improved with ADE treatment. Finally, we may infer that Phyto-constituents of ADE have the potential to protect against B(a)P-induced lung pathogenesis. Therefore, Ajwa dates might be used to develop a possible potent alternative therapy for lung pathogenesis. | b83c0eeae5f9900cc91b945c215e2a89c180ff8b | Crossref | Environmental Science, Medicine | null | DOI:10.3390/app12136784 |
41,564,295 | pes2o/s2ag | v3-fos-license | 2017-02-11T23:31:31.025Z | 2009-03-16T00:00:00.000 | Suspended Stripline Filters Integrated with Standard Multilayer Printed Circuit Boards | Suspended stripline (SSL) is a good transmission line medium for the realization of filters. One drawback, however, are problems in integrating such filters into extended circuits. To overcome this problem, different SSL filters were designed and tested, realized on a multilayer board consisting of a standard printed circuit board (FR4) and a microwave substrate laminated on top. The necessary channel for the SSL is formed by rows of vias in the multilayer together with a cap fixed on top of the filter structure. While lowpass and highpass filters easily show good results, a higher fabrication accuracy and the inclusion of dielectric dispersion and anisotropy of the FR4 material is necessary for good results of bandpass filters. | 6303d0e3f00fd25563432b670ae5c0fdefb20382 | MAG, IEEE, ScienceParseMerged, Unpaywall | Engineering, Physics | Materials Science | DOI:10.1109/GEMIC.2009.4815904, MAG:2081487919 |
86,112,095 | pes2o/s2ag | v3-fos-license | 2019-03-30T13:05:36.441Z | 2014-01-01T00:00:00.000 | Aboveground productivity and soil carbon storage of biofuel crops in Ohio | Biofuel crops may help achieve the goals of energy‐efficient renewable ethanol production and greenhouse gas (GHG) mitigation through carbon (C) storage. The objective of this study was to compare the aboveground biomass yields and soil organic C (SOC) stocks under four crops (no‐till corn, switchgrass, indiangrass, and willow) 7 years since establishment at three sites in Ohio to determine if high‐yielding biofuel crops are also capable of high levels of C storage. Corn grain had the highest potential ethanol yields, with an average of more than 4100 L ha−1, and ethanol yields increased if both corn grain and stover were converted to biofuel, while willow had the lowest yields. The SOC concentration in soils under biofuels was generally unaffected by crop type; at one site, soil in the top 10 cm under willow contained nearly 13 Mg C ha−1 more SOC (or 29% more) than did soils under switchgrass or corn. Crop type affected SOC content of macroaggregates in the top 10 cm of soil, where macroaggregates in soil under corn had lower C, N and C : N ratios than those under perennial grasses or trees. Overall, the results suggest that no‐till corn is capable of high ethanol yields and equivalent SOC stocks to 40 cm depth. Long‐term monitoring and measurement of SOC stocks at depth are required to determine whether this trend remains. In addition, ecological, energy, and GHG assessments should be made to estimate the C footprint of each feedstock. | 836d185c3eadf3fd1ac018ecb1a30f9da2582db8 | MAG, MergedPDFExtraction, Wiley, Unpaywall | Environmental Science, Agricultural and Food Sciences | Environmental Science | DOI:10.1111/gcbb.12041, MAG:2134392664 |
263,967,110 | pes2o/s2ag | v3-fos-license | 2023-10-14T06:17:46.228Z | 2023-10-02T00:00:00.000 | Pesticides in rice-based products commercialised in Argentina | ABSTRACT People with coeliac disease have a limited diet. Therefore, rice-based products are an ideal alternative. Highlighting this import item, an analytical methodology was validated to determine pesticides in rice-based product samples. The precision was satisfactory for all pesticides since the RSD did not exceed 13% in any case. Regarding recovery, the method had values close to 100%. The limit of quantification was established at 10 µg/kg and the expanded uncertainty was less than 20%. After validation, 80 samples of toasts and rice crackers were analysed. All samples were compliant with the national regulations for dichlorvos and tebuconazole. The pesticide that was present in the highest number of samples was pirimiphos – methyl, but all below the maximum residue limit. From all samples analysed, 38 were positive for at least one pesticide and only one contained four pesticides simultaneously: deltamethrin, pirimiphos-methyl, kresoxim-methyl and epoxiconazole. | 7e5f8c1d9018dca69b1d08763e148696354ea431 | Medline, ScienceParsePlus, Crossref, TaylorAndFrancis | Environmental Science, Agricultural and Food Sciences | Medicine | DOI:10.1080/19393210.2023.2252782 |
2,656,810 | pes2o/s2ag | v3-fos-license | 2014-10-01T00:00:00.000Z | 2013-05-01T00:00:00.000 | State of the "Art”: A Taxonomy of Artistic Stylization Techniques for Images and Video | This paper surveys the field of nonphotorealistic rendering (NPR), focusing on techniques for transforming 2D input (images and video) into artistically stylized renderings. We first present a taxonomy of the 2D NPR algorithms developed over the past two decades, structured according to the design characteristics and behavior of each technique. We then describe a chronology of development from the semiautomatic paint systems of the early nineties, through to the automated painterly rendering systems of the late nineties driven by image gradient analysis. Two complementary trends in the NPR literature are then addressed, with reference to our taxonomy. First, the fusion of higher level computer vision and NPR, illustrating the trends toward scene analysis to drive artistic abstraction and diversity of style. Second, the evolution of local processing approaches toward edge-aware filtering for real-time stylization of images and video. The survey then concludes with a discussion of open challenges for 2D NPR identified in recent NPR symposia, including topics such as user and aesthetic evaluation. | d24343feff22ab6839de2f7c659734489b9bb11b | Grobid, Anansi, Medline, Crawler, DBLP, ScienceParseMerged, MergedPDFExtraction, MAG, CiteSeerX, Unpaywall, IEEE, Crossref | Art, Computer Science | Computer Science, Medicine | DOI:10.1109/TVCG.2012.160, MAG:2109253138 |
247,085,241 | pes2o/s2ag | v3-fos-license | 2022-02-25T14:16:26.858Z | 2021-09-24T00:00:00.000 | Explainable Hybrid CNN and FNN Approach Applied on Robotic Wall-Following Behaviour Learning | Fuzzy Neural Network (FNN) applied to robotic control tasks has proved to be effective by previous researchers. However, FNN has an inherent deficiency in dealing with inputs of large dimensions, such as images. Therefore, this research utilizes a Convolutional Neural Network (CNN) model to convert image into distance values and delivers these values to FNN based robot controller as inputs. The proposed hybrid CNN+FNN are tested with both a regression model and a multi-task model. Results show that the multi-task method performs better with less information loss from input images. This paper also proved that the proposed hybrid approach can be generalized into an unknown robotic simulation environment and performs better than its FNN counterpart. By utilizing state of the art explainable analysis method, both the CNN part and the FNN part of the hybrid approach can be explained in a human-understandable way. | 2885ecc9664336f481641e54cc78460f2d821aea | Crossref, DBLP, ScienceParsePlus, MergedPDFExtraction, ACM | Computer Science, Engineering | Computer Science | DOI:10.1145/3488933.3489026 |
258,504,636 | pes2o/s2ag | v3-fos-license | 2023-05-05T15:14:12.634Z | 2023-05-02T00:00:00.000 | Long time behaviour for solutions to a particular wave equation | In this paper, a wave problem, involving an anisotropic differential operator is considered. Such kind of problems can be used to modelise seismic phenomena or electrorheological smart fluid. Existence of local solution is obtained in a particular case. An asymptotic analysis is made, with the aim to obtain the long time behaviour of a solution, more precisely we establish a kind of polynomial decay. | a34e69db081c73e66e5b8451158bcaff4719e00c | Crossref, Wiley, ScienceParsePlus, MergedPDFExtraction | Mathematics | null | DOI:10.1002/zamm.202200618 |
46,549,686 | pes2o/s2ag | v3-fos-license | 2018-04-03T06:23:22.792Z | 1980-01-12T00:00:00.000 | Permissiveness and Dr. Blatz: where did society's ideas on child-raising go wrong? | The erosion of traditional discipline, in the home and at school, has been going on for the last half century at least. Yet it is arguable whether our society is, even now, a truly permissive one. What is clear, however, is that it is more permissive than it was, a situation credited with spawning the disrespect for authority, the student assaults in our schools and the general mayhem on the streets that are regularly reported by the media. Whether this is a valid cause-and-effect relationship is also argued among many disciplines, all of whom are at least agreed that something, somewhere, has gone wrong. The vagaries of society's tides are not easily subject to rational analysis but in the International Year of the Child this pediatrician might be excused from thinking that no aspect of our inquiry into children's welfare is more important than trying to untangle the relationship between our philosophy of child raising and the product that finally emerges. One place to start might be the teaching of one of the pioneer progressives, so we may see, if we can, where we got off the track. In 1924 Dr. William Emet Blatz (1895-1964) came back to the department of psychology in the University of Toronto and established (and subsequently directed) one of the first nursery schools in North America, the St. George Nursery School, which became the St. George School for Child Study and eventually the present Institute of Child Study. In the early 1930s he also became the director of the Windy Ridge Day School, which accepted children up to 8 years of age. He taught a consistent doctrine of education and child rearing sharply at variance with the traditional approaches. He brought to Toronto the new aspiring science of child psychology and its offshoot, progressive education. He made parents aware that self-expression is a legitimate need of every child, that rigid parental domination is harmful, that blind obedience is the fundamental basis of fascism, that punishment is to be avoided as a very inefficient adjunct to any learning process, that corporal punishment hitting a child is an admission of failure, demeaning to parent and child and contraindicated absolutely, that right and wrong are relative terms, that obedience and disobedience are simply different forms of usually normal child reactions and that hammering nails in the piano has a certain educational value for the growing child | aba8808c3e086917cd7b022ec6e4fb5c93343cb5 | MAG, MergedPDFExtraction, Adhoc, Medline, ScienceParsePlus | Education | Medicine, Computer Science | MAG:1543964185 |
39,431,536 | pes2o/s2ag | v3-fos-license | 2017-08-15T04:54:34.291Z | 1986-03-01T00:00:00.000 | Plasmodium berghei sporozoite invasion is blocked in vitro by sporozoite-immobilizing antibodies | A monoclonal antibody directed against the circumsporozoite protein on the surface of Plasmodium berghei sporozoites inhibited sporozoite motility in vitro. These immobilized sporozoites could adhere to but not invade target cultured cells. Other sporozoite-immobilizing agents also inhibited sporozoite invasion into cultured cells and did not prevent sporozoite adherence. These results indicate that sporozoite invasiveness is associated with sporozoite motility. Thus, the immobilizing effect of this antibody could explain its functional activity against sporozoite invasion in vivo. | 57a5c5d3ccf720f0101cd7eadab523f86fd81052 | ASMUSA, Unpaywall, Anansi, MAG, ScienceParseMerged, Medline, MergedPDFExtraction | Biology | Medicine, Biology | DOI:10.1128/iai.51.3.859-864.1986, MAG:1517347742 |
205,808,036 | pes2o/s2ag | v3-fos-license | 2018-04-03T00:15:36.157Z | 2013-01-04T00:00:00.000 | Gold nanoparticle research before and after the Brust-Schiffrin method. | In this viewpoint we discuss the early contribution from Brust et al., which is not only the most cited paper ever published in Chem. Commun., but also a landmark in gold nanoparticle research and in nanotechnology. We provide here an overview of its major contributions and how the field has evolved since its publication in 1994. | 61525f9763ed8046bc8f52d486bbd899c4c1b81a | Unpaywall, Medline, MAG, ScienceParseMerged | Chemistry, Materials Science | Materials Science, Medicine | DOI:10.1039/c2cc35720h, MAG:2088338951 |
270,258,936 | pes2o/s2ag | v3-fos-license | 2024-06-06T13:12:06.414Z | 2024-06-02T00:00:00.000 | Dimensionality Reduction and Denoising of Spatial Transcriptomics Data Using Dual-Channel Masked Graph Autoencoder | Recent advances in spatial transcriptomics (ST) technology allow researchers to comprehensively measure gene expression patterns at the level of individual cells or even subcellular compartments while preserving the spatial context of their tissue. Spatial domain identification is a critical task in analyzing the ST data. However, effectively capturing distinctive gene expression features and relationships between genes poses a significant challenge. We develop a graph self-supervised learning method STMask for the analysis and exploration of the ST data. STMask combines the masking mechanism with a graph autoencoder, compelling the gene representation learning channel to acquire more expressive representations. Simultaneously, it combines the masking mechanism with graph self-supervised contrastive learning methods, pulling together the embedding distances between spatially adjacent points and pushing apart the representations of different clusters, allowing the gene relationship learning channel to learn more comprehensive relationships. The applications of STMask to four ST datasets demonstrate that STMask outperforms state-of-the-art methods in various tasks, including spatial clustering and trajectory inference. Source code is available at https://github.com/donghaifang/STMask. Author summary Spatial Transcriptomics (ST) is an emerging transcriptomic sequencing technology aimed at revealing the spatial distribution of gene expression and cell types within tissues. This method enables the acquisition of gene expression profiles at the level of individual cells or spots within the tissue, uncovering the spatial expression patterns of genes. However, accurately identifying spatial domains in ST data remains challenging. In our study, we introduce STMask, a self-supervised learning method that combines a dual-channel masked graph autoencoder with masking and contrastive learning. Our work contributes primarily in two aspects: (1) We propose a novel graph self-supervised learning method (STMask) specifically tailored for the analysis and research of ST data, which enhances the ability to capture the unique features of gene expression and spatial relationships within tissues. (2) Through comprehensive experiments, STMask provides valuable insights into biological processes, particularly in the context of breast cancer. It identifies enrichment of various differentially expressed genes in tumor regions, such as IGHG1, which can serve as effective targets for cancer therapy. | 98bfe613855ea3979e15aecccdd41bfd09ef1ed7 | BioRxiv, ScienceParsePlus | Computer Science, Biology | Biology | DOI:10.1101/2024.05.30.596562 |
270,328,965 | pes2o/s2ag | v3-fos-license | 2024-06-08T15:17:43.381Z | 2024-06-06T00:00:00.000 | What is at stake and what does it take? Collaborative governance and policy (in)action in the adoption of a National Forest Programme | Inspired by collaborative governance theory, this study analyzes the process dynamics, outputs, and perceived impacts of a collaborative initiative launched by the Swedish government in 2014. It draws on extensive empirical sources related to the Swedish government's efforts to develop and implement a National Forest Programme (NFP) from 2014 to 2021. These sources include semistructured interviews, observations, public consultation comments, records of meetings and public hearings, reports from dialogues, and enacted policy documents. The results show that the collaboration initially provided a space for joint deliberation and capacity building on complex and contentious issues related to current land use. However, the final programme endorsed by the government in 2018 failed to initiate ambitious proposals on several key issues raised by participating actors, offering little indication of priorities and policy instruments to address fundamental gaps in current policy goals and their implementation. Consequently, the case reveals that it was not sufficient, and perhaps not even desirable, to address existing conflicts and policy problems in a comprehensive collaborative setting run by the Government Offices. The paper concludes with key insights for research on collaboration and suggests ways to move forward with policy designs that integrate multiple and competing policy goals in contested areas. | 3a608e98b5a83c31f3d96c18975f41d120fc36b8 | Crossref | Environmental Science, Political Science | null | DOI:10.1111/1467-9477.12284 |
109,082,298 | pes2o/s2ag | v3-fos-license | 2019-04-12T13:56:12.750Z | 1994-07-22T00:00:00.000 | Earth Penetration Radar Imaging System field measurements | This paper describes site measurements and resulting images of buried objects made with the Earth Penetration Radar Imaging System (EPRIS) developed by Coleman Research Corporation (CRC). EPRIS makes use of frequency stepped radar technology and synthetic aperture imaging algorithms for nonintrusive characterization and imaging of buried objects, contamination, and geological or hydrological features. This paper is an extension or follow-up to CRC's EPRIS paper presented at last year's OE/AEROSPACE convention in Orlando, FL. It gives a brief description of the EPRIS system and contains the results from several DOE site surveys. These results include 2D and 3D images of buried test targets as well as images of actual buried waste and hydrological or geological features. The paper concludes with the recommendations or suggestions that should be followed up on future efforts. | 9067539e82a84574718ddb114661e1b45ff066fc | SPIE, ScienceParseMerged, Unpaywall, MAG | Engineering, Environmental Science | Engineering | DOI:10.1117/12.179964, MAG:1975463465 |
61,667,529 | pes2o/s2ag | v3-fos-license | 2019-02-15T14:04:24.169Z | 1996-10-15T00:00:00.000 | Combined coding and quadratic detection for DS/CDMA systems operating in Rayleigh fading channels | We present the true union bound of a DS/CDMA system that employs convolutional coding and a quadratic detector. In our study, the total bandwidth expansion factor caused by coding and spreading is fixed and the channel is assumed to exhibit Rayleigh flat fading. The objective is to assess the performance of various quadratic detectors as a function of the spreading factor and the fade rate. Specifically, four detectors were considered: chip level differential detection, chip level maximum likelihood sequence estimation, noncoherent detection, and perfect coherent detection. It was found that in the presence of fast Rayleigh fading, different detectors behave differently when the spreading factor varies. For example, the chip level differential detector and the ideal coherent detector favour a small spreading factor and a low rate code, while the MLSE prefers a high rate code and a high spreading factor. For the noncoherent detector, there actually exists an optimal system configuration at certain fade rates. | 8c5f1ff71d9405dce71fec527e14705b6cd408fe | MAG, DBLP, IEEE, Unpaywall, ScienceParseMerged | Engineering, Computer Science | Computer Science | DOI:10.1109/PIMRC.1996.568457, MAG:1561435471 |
25,581,629 | pes2o/s2ag | v3-fos-license | 2018-04-03T02:53:36.727Z | 2012-04-01T00:00:00.000 | Preemptive use of plerixafor in difficult‐to‐mobilize patients: an emerging concept | Mobilized peripheral blood (PB) is the preferred source of stem cells (PBSCs) for autologous stem cell transplantation (ASCT). The use of cytokines, alone or in combination with chemotherapy (chemomobilization), is currently the most common strategy applied to collect PBSCs. However, a significant proportion of patients with lymphoid malignancies fail to mobilize enough PBSCs to proceed to ASCT. Plerixafor has been recently introduced for clinical use to enhance PBSC mobilization and has been shown to be more effective than granulocyte–colony‐stimulating factor (G‐CSF) alone in patients with multiple myeloma or non‐Hodgkin's lymphoma. There is limited experience on combining plerixafor with chemotherapy plus G‐CSF in patients who mobilize poorly. This review attempts to summarize the published experience on the preemptive use of plerixafor after chemomobilization or G‐CSF mobilization to enhance stem cell collection and to prevent mobilization failure. Current evidence suggests that addition of plerixafor is safe and effective in the large majority of the patients with low blood CD34+ cell counts after mobilization and/or poor yield after the first collection(s). Circulating CD34+ cell counts can be increased by severalfold with plerixafor and the majority of the patients considered difficult to mobilize can be successfully collected. Although more studies are needed to evaluate proper patient selection and optimal timing for the addition of plerixafor after chemotherapy, its mechanism of action inducing the rapid release of CD34+ cells from the marrow to the PB makes this molecule suitable for its “preemptive” use in patients who are difficult to mobilize. | fc9cab39fa32037698215e732f5d2335ab4fab6f | Wiley, MergedPDFExtraction, MAG, Medline, Unpaywall | Medicine | Medicine | DOI:10.1111/j.1537-2995.2011.03349.x, MAG:2170436183 |
121,799,279 | pes2o/s2ag | v3-fos-license | 2019-04-19T13:12:40.083Z | 2008-10-01T00:00:00.000 | The giants of excess: a challenge to the nation's health | Summary. Sir William Beveridge in his famous report wanted to eliminate the five giants of want, squalor, idleness, ignorance and disease: the giants of too little. However, the problems facing welfare states are more the giants of too much: the giants of excess. For health in particular, excessive behaviours of various kinds contribute significantly to the major sources of morbidity and mortality in our society, including cancer, heart disease, stroke, diabetes and kidney and liver diseases. There are few good theories about why individuals engage in excess behaviours. But it is clear that one of the main problems that face both individuals and the government or other agencies tasked with improving health is that the costs of most unhealthy activities impact in the future, whereas the benefits from them occur in the present. Policies have to be developed that either bring some of the costs from unhealthy activities (or the benefits from healthy ones) back from the future, or reduce some of the benefits from unhealthy activities (or reduce the costs of healthy ones) in the present. To avoid the danger of the ‘nanny state’, they should also not impact too greatly on individual freedom or autonomy. Promising ideas that meet these criteria, which are derived from the philosophy of libertarian paternalism, include smoking permits and exercise hours. | f0eff34dd4e12adb81defde14bfdd308fbc50da7 | MergedPDFExtraction, Wiley, MAG, Unpaywall | Medicine, Political Science | Business | DOI:10.1111/j.1467-985X.2008.00549.x, MAG:2062534682 |
268,692,407 | pes2o/s2ag | v3-fos-license | 2024-03-27T13:10:03.819Z | 2024-03-24T00:00:00.000 | Link Prediction in Multilayer Networks via Cross-Network Embedding | Link prediction is a fundamental task in network analysis, with the objective of predicting missing or potential links. While existing studies have mainly concentrated on single networks, it is worth noting that numerous real-world networks exhibit interconnectedness. For example, individuals often register on various social media platforms to access diverse services, such as chatting, tweeting, blogging, and rating movies. These platforms share a subset of users and are termed multilayer networks. The interlayer links in such networks hold valuable information that provides more comprehensive insights into the network structure. To effectively exploit this complementary information and enhance link prediction in the target network, we propose a novel cross-network embedding method. This method aims to represent different networks in a shared latent space, preserving proximity within single networks as well as consistency across multilayer networks. Specifically, nodes can aggregate messages from aligned nodes in other layers. Extensive experiments conducted on real-world datasets demonstrate the superior performance of our proposed method for link prediction in multilayer networks. | 03377f8307e2aac4bca3b0bb51c9481c2f696830 | DBLP, Crossref, ScienceParsePlus, Anansi | Computer Science | Computer Science | DOI:10.1609/aaai.v38i8.28742 |
40,097,878 | pes2o/s2ag | v3-fos-license | 2018-04-03T04:43:55.079Z | 2009-08-17T00:00:00.000 | Oxidation of carbon monoxide cocatalyzed by palladium(0) and the H(5)PV(2)Mo(10)O(40) polyoxometalate probed by electron paramagnetic resonance and aerobic catalysis. | The H(5)PV(2)Mo(10)O(40) polyoxometalate and Pd/Al(2)O(3) were used as co-catalysts under anaerobic conditions for the activation and oxidation of CO to CO(2) by an electron transfer-oxygen transfer mechanism. Upon anaerobic reduction of H(5)PV(2)Mo(10)O(40) with CO in the presence of Pd(0) two paramagnetic species were observed and characterized by continuous wave electron paramagnetic resonance (CW-EPR) and hyperfine sublevel correlation (HYSCORE) spectroscopic measurements. Major species I (65-70%) is assigned to a species resembling a vanadyl cation that is supported on the polyoxometalate and showed a bonding interaction with (13)CO. Minor species II (30-35%) is attributed to a reduced species where the vanadium(IV) atom is incorporated in the polyoxometalate framework but slightly distanced from the phosphate core. Under aerobic conditions, CO/O(2), a nucleophilic oxidant was formed as elucidated by oxidation of thianthrene oxide as a probe substrate. Oxidation reactions performed on terminal alkenes such as 1-octene yielded a complicated mixture of products that was, however, clearly a result of alkene epoxidation followed by subsequent reactions of the intermediate epoxide. The significant competing reaction was a hydrocarbonylation reaction that yielded a approximately 1:1 mixture of linear/branched carboxylic acids. | ee86839b0b7a3aeba2bac02d12f7a634925be5ed | Unpaywall, MAG, Medline | Chemistry | Medicine, Chemistry | DOI:10.1021/ic900868t, MAG:2949969768 |
39,623,628 | pes2o/s2ag | v3-fos-license | 2018-04-03T04:33:58.984Z | 2007-06-23T00:00:00.000 | (1)H relaxivity of water in aqueous suspensions of Gd(3+)-loaded NaY nanozeolites and AlTUD-1 mesoporous material: the influence of Si/Al ratio and pore size. | The results of a (1)H nuclear magnetic relaxation dispersion (NMRD) and EPR study on aqueous suspensions of Gd(3+)-loaded NaY nanozeolites and AlTUD-1 mesoporous material are described. Upon increase of the Si/Al ratio from 1.7 to 4.0 in the Gd(3+)-loaded zeolites, the relaxation rate per mM Gd(3+) (r1) at 40 MHz and 25 degrees C increases from 14 to 27 s(-)1 mM(-1). The NMRD and EPR data were fitted with a previously developed two-step model that considers the system as a concentrated aqueous solution of Gd(3+) in the interior of the zeolite that is in exchange with the bulk water outside the zeolite. The results show that the observed increase in relaxivity can mainly be attributed to the residence lifetime of the water protons in the interior of the material, which decreased from 0.3 to 0.2 micros, upon the increase of the Si/Al ratio. This can be explained by the decreased interaction of water with the zeolite walls as a result of the increased hydrophobicity. The importance of the exchange rate of water between the inside and the outside of the material was further demonstrated by the relatively high relaxivity (33 s(-1) mM(-1) at 40 MHz, 25 degrees C) observed for a suspension of the Gd(3+)-loaded mesoporous material AlTUD-1. Unfortunately, Gd(3+) leaches rather easily from that material, but not from the Gd(3+)-loaded NaY zeolites, which may have potential as contrast agents for magnetic resonance imaging. | e0f8107ae1281cdce9f36d500bdd4d1139aa3d9a | MAG, Medline, Unpaywall | Chemistry, Materials Science | Chemistry, Medicine | DOI:10.1021/IC700699N, MAG:2035674872 |
83,996,845 | pes2o/s2ag | v3-fos-license | 2018-04-03T01:14:57.187Z | 2007-02-06T00:00:00.000 | Design and characterization of a traceable protein kinase Calpha. | Protein kinase Calpha (PKCalpha) is a critical component of pathways that govern cancer-related phenotypes such as invasion and proliferation. Proteins that serve as immediate substrates for PKCalpha offer potential targets for anticancer drug design. To identify specific substrates, a mutant of PKCalpha (M417A) was constructed at the ATP binding site such that it could bind a sterically large ATP analogue derivatized through the N6 amino group of adenosine ([gamma-32P]-N6-phenyl-ATP). Because this analogue could be utilized by the mutant kinase but not by wild-type PKCalpha (or presumably other protein kinase) to phosphorylate peptide or protein substrates, 32P-labeled products were the direct result of the mutant PKCalpha. Kinetic analysis with [gamma-32P]-N6-phenyl-ATP revealed that the mutant retained undiminished affinity for the peptide substrate (Km = 12.4 microM) and a Vmax value (10.3 pmol/min) that was only 3-fold lower than that exhibited by the wild-type enzyme with natural ATP. However, with [gamma-32P]ATP, the mutant had a somewhat lower affinity (Km = 82.8 microM) than the wild-type enzyme (Km = 9.3 microM) in vitro but was competent in causing aggressive motility in nonmotile MCF-10A human breast cells (with endogenous ATP), as previously described for wild-type PKCalpha. The FLAG-tagged PKCalpha mutant was expressed in MCF-10A cells and used to co-immunoprecipitate high-affinity substrates from lysates. Immunopellets were reacted with [gamma-32P]-N6-phenyl-ATP, and radiolabeled products were analyzed by SDS-PAGE and autoradiography. Mass spectrometry of selected bands identified several known substrates of PKC, thereby validating the methods used in these studies. These findings provide a foundation for future applications of this traceable PKCalpha mutant. | 48b41b8c24418b8bf5918a75c7638c131ec05b61 | MAG, Medline, Unpaywall | Chemistry, Medicine | Medicine, Biology | DOI:10.1021/BI0622017, MAG:1971734782 |
215,899,745 | pes2o/s2ag | v3-fos-license | 2020-03-12T10:46:52.631Z | 2020-03-10T00:00:00.000 | Secure data deletion in cloud storage: a survey | With the rapid development of cloud computing, individual people, firms, industries and governments are moving their data to clouds to meet the data explosion challenge. Secure data deletion is becoming a hot issue in cloud storage research. Different from traditional data deletion, the securely deleted data should be non-recoverable. In this paper, we present a survey of current secure data deletion technologies and make comparisons of them for both private cloud storage and public cloud storage. For private cloud storage, we introduce two main deletion methods: physical destruction and disk replication. For public cloud storage, we analyse the existing deletion methods such as balanced-tree-based, trusted-third-parties-based, policy-based secure data deletion methods and so on, in accordance with the two aspects of verifiable secure data deletion and verifiable non-recoverability of data. Finally, we analyse the deficiencies among current researches and propose some future directions for improvement in secure data deletion. | c81ae3d7274251a1679f8993fca1805b5ddada7e | Unpaywall, MAG, Crossref, DBLP | Computer Science | Computer Science | DOI:10.1504/ijes.2020.10027520, MAG:3011025429 |
14,097,457 | pes2o/s2ag | v3-fos-license | 2014-10-01T00:00:00.000Z | 2007-10-01T00:00:00.000 | Prime decomposition in the anti-cyclotomic extension | For an imaginary quadratic number field K and an odd prime number l, the anti-cyclotomic Z l -extension of K is defined. For primes p of K, decomposition laws for p in the anti-cyclotomic extension are given. We show how these laws can be applied to determine if the Hilbert class field (or part of it) of K is Z l -embeddable. For some K and l, we find explicit polynomials whose roots generate the first step of the anti-cyclotomic extension and show how the prime decomposition laws give nice results on the splitting of these polyniomials modulo p. The article contains many numerical examples. | c59742decb7454952fb3010e075a224e64212322 | ScienceParseMerged, Anansi, DBLP, Grobid, CiteSeerX, MAG, MergedPDFExtraction, Unpaywall | Mathematics | Computer Science, Mathematics | DOI:10.1090/S0025-5718-07-01964-3, MAG:1994599525 |
237,549,007 | pes2o/s2ag | v3-fos-license | 2021-09-18T13:08:38.620Z | 2021-07-18T00:00:00.000 | Text Mining in Cybersecurity | The growth of data volume has changed cybersecurity activities, demanding a higher level of automation. In this new cybersecurity landscape, text mining emerged as an alternative to improve the efficiency of the activities involving unstructured data. This article proposes a Systematic Literature Review (SLR) to present the application of text mining in the cybersecurity domain. Using a systematic protocol, we identified 2,196 studies, out of which 83 were summarized. As a contribution, we propose a taxonomy to demonstrate the different activities in the cybersecurity domain supported by text mining. We also detail the strategies evaluated in the application of text mining tasks and the use of neural networks to support activities involving unstructured data. The work also discusses text classification performance aiming its application in real-world solutions. The SLR also highlights open gaps for future research, such as the analysis of non-English content and the intensification in the usage of neural networks. | 26050f65dfb4f406ffe662c228b9e73db03f3ec0 | DBLP, MAG, ScienceParsePlus, MergedPDFExtraction, ACM | Computer Science | Computer Science | DOI:10.1145/3462477, MAG:3185296261 |
148,806,394 | pes2o/s2ag | v3-fos-license | 2019-05-11T13:04:10.377Z | 2015-07-05T00:00:00.000 | Book Review: Metrolingualism: Language in the city | faced by both official language communities and indeed emphasize how much they have in common within a Canadian context. But it is Fraser who comes closest to offering a broad perspective on what is essentially an ageing population and atrophying community relative to pre-1970s conditions. The Language Commissioner makes a plea for investment in youth, in education, and in a stronger federal–provincial partnership to sustain the official English language community for which he has formal responsibility. He reminds English-speaking Quebec that “your culture continues to thrive, with internationally recognized artists and authors. Your educational institutions continue to survive, attracting students from all over Canada and the world. And yet, you must work to keep up the momentum” (p. 392). This is a stimulating volume that seeks to address and unpack the twin dimensions of Anglophone community life in Quebec, namely, that its members remain part of a privileged subsection of the Canadian population and that they inhabit an institutional infrastructure and sociolegal environment that is the envy of their counterparts among the Official Francophone communities out with Quebec. The contributors have demonstrated a great deal of internal variability within the Anglophone community, have made a robust defense of its long-term vitality, which it is argued is important for both Quebec and Canada, and have made prescient recommendations by which such vitality can be promoted, protected, and regulated. Perhaps the most significant recommendation in this regard is made by the editor when he justifies his priority action as selecting the treatment of Anglophones and their institutional support as a benchmark to be used to bolster the further development of Francophone minorities across Canada. Whether it is a win-win stratagem for both official language communities only time will tell, but at least this volume provides ready data and relevant arguments for such an attempt to be made. | a3de756fee3790a639edbc6ab037115c2d533fc4 | MAG, Unpaywall, Sage, MergedPDFExtraction | Linguistics | Sociology, Psychology | DOI:10.1177/0261927X15594649, MAG:2910594611 |
71,142,944 | pes2o/s2ag | v3-fos-license | 2019-03-08T14:03:11.318Z | 2019-01-01T00:00:00.000 | Secure Neighbour Discovery: Secure k-Nearest ROUTING AD-HOC Networking Using Diffie-Helman and HIGHEST Connectivity Algorithm | —The approach of splendid flexible contraptions and zone-based applications, and customers’ movability configuration are seen to be exceedingly dependent on moving zones. Proficiency and effortlessness of irregular algorithms have made transfer of data a lucrative option for taking care of complex issues in the space of correspondence systems. Achieving efficiency with the mobility of wireless communication is tedious. To deal with this, the data are sent through the chosen nodes. The data are forwarded to a destination via the primary path from source. Remote framework organizations rely highly on a basic structure for neighborhood discovery (ND). Neighborhood Discovery (ND) is the disclosure of gadgets specifically reachable for correspondence or in physical nearness, which becomes a key necessity and building obstruct for different data transfer applications. A completely conveyed and agreeable arrangement that is powerful against free and plotting foes can be weakened just by a staggering nearness of enemies and distributed solution for (Neighbor Position Verification) NPV, which permits any hub in a portable unplanned system to confirm the situation of its correspondence neighbors without considering the prior reliable nodes. Deffie-Hellman (DH) algorithm and HCS clustering algorithm have been implemented to make safe transmission between nodes and receiving nodes or clients without any traffic or data loss. The data are passed to destination by using grid topology. Our comparison of the proposed system with existing systems demonstrates that our convention is exceptionally strong concerning communication cost, energy, average delay, accessing of data and PDR. | bb2dfeae07751c37ed90c1a64b24363fe5adf66a | Crossref, DBLP, Unpaywall, MergedPDFExtraction, Anansi, MAG | Computer Science | Computer Science | DOI:10.12720/jcm.14.3.164-169, MAG:2935093607 |
15,093,596 | pes2o/s2ag | v3-fos-license | 2017-02-18T10:02:29.759Z | 2009-07-10T00:00:00.000 | Measurement Based P2P Streaming Media System Topology Analysis | Snapshot is usually applied in p2p network topology analysis. In this paper, we develop the topology crawler software to probe the PPLive application. Based on the measured trace, we characterize the PPLive topology with metrics including degree distribution, clustering coefficient, network diameter, characteristic path length, connectivity matrix and reciprocity coefficient. In additional, we also use visualization methods (BOSAM and pajek) to analyzing the network. We compare the characteristics of PPLive with that of Gnutella, UUSee, and ER random network. | 6f379a362e7d757344ea7f7f38834524ce97991e | Grobid, Unpaywall, IEEE, MAG, ScienceParseMerged | Computer Science | Computer Science | DOI:10.1109/ICIE.2009.203, MAG:2145763016 |
19,261,096 | pes2o/s2ag | v3-fos-license | 2018-04-03T06:17:59.042Z | 1977-09-01T00:00:00.000 | [Effect of hydantoins on urinary excretion of 5-hydroxyindoleacetic acid]. | The investigations were carried out in 10 patients with epileptic seizures. The obtained results were compared with those in a control group of 20 healthy subjects. The 24-hour urinary excretion of 5-HIAA efore hydantoinal and on the 1st, 2dn and 3rd days of hydantoinal administration was determined by the method of Udenfried et al. as modified by McFarlane et al. It was found that healthy subjects excreted significantly more 5-HIAA before and after hydantoinal load. Administration of this drug increased significantly the excretion of this metabolite with urine, in healthy subjects but in epileptics it had no significant effect on 5-HIAA level in 24-hour urine. | 8f899caee3a6fd9c2c00ff82bfa0e81ad57818ae | MAG, Medline | Medicine | Medicine | MAG:2405972857 |
233,228,551 | pes2o/s2ag | v3-fos-license | 2021-04-14T16:18:04.342Z | 2021-04-12T00:00:00.000 | A Call to the Profession: Rejuvenating the Multicultural Conversation | In this rejoinder, the authors respond to the feedback and suggestions offered by Vandiver et al. (2021). We clarify that the intent of our Major Contribution is to rejuvenate the conversation regarding multicultural counseling competence, continue the quest to operationalize the construct, and propose the process model of multicultural counseling competence. In response to our colleagues’ reaction article, we organized this rejoinder into three sections: major points of agreement, major points of disagreement, and mixed points of view, before concluding again with our intention and remembering the importance of continuing the work. | 5890d12a2b4a4b2c9efe02e8335541db9255e904 | Crossref, MergedPDFExtraction, Sage | Business | null | DOI:10.1177/0011000021991872 |
49,650,101 | pes2o/s2ag | v3-fos-license | 2018-07-12T07:59:37.373Z | 2018-09-30T00:00:00.000 | Thiazide Therapy in Chronic Kidney Disease: Renal and Extra Renal Targets. | BACKGROUND
Thiazides are the most commonly used medications for the treatment of mild and moderate hypertension. Despite their recognized effect, the mechanism by which thiazides reduce systemic blood pressure remains uncertain. The prevailing belief is that thiazides reduce blood pressure primarily via enhancement of salt excretion consequent to the inhibition of the Na-Cl Cotransporter (NCC) in the Distal Convoluted Tubules (DCT). However, recent reports point to a reduction in peripheral vascular resistance as a major mechanism of antihypertensive effect of thiazides. It is plausible that both mechanisms, renal and extra-renal, may be operating simultaneously. Recent studies point to compensatory mechanisms in the kidney distal nephron that may play a role in blunting the diuretic effect of thiazides. Not much information is available about the efficacy of thiazides in controlling blood pressure in individuals with Chronic Kidney Disease (CKD).
OBJECTIVE
This review will discuss the latest updates on the use and efficacy of thiazides derivatives as diuretics and antihypertensive medications in CKD patients.
CONCLUSION
Thiazides remain effective as diuretics and antihypertensive agents in individuals with low GFR. | 81179bf45372152a946be0da3af3ecdd458850b7 | Crossref, Medline, Unpaywall, MAG | Medicine | Medicine | DOI:10.2174/1389200219666180702104559, MAG:2811367821 |
47,353,051 | pes2o/s2ag | v3-fos-license | 2017-02-18T07:12:06.986Z | 2009-01-01T00:00:00.000 | A novel single-stage high power factor electronic ballast for metal halide lamps free of acoustic resonance | This paper proposes a novel single-stage high-power-factor electronic ballast for metal halide lamps. By integrating two buck-boost typed power-factor-correction converters, a full-bridge inverter and a bidirectional buck converter, a single-stage electronic ballast with symmetrical circuit topology is derived. The circuit component count can be effectively reduced and circuit energy-conversion efficiency is improved. With a tactful control scheme, the proposed electronic ballast can output a low-frequency square-wave voltage to drive metal halide lamps. The problematic phenomena of acoustic resonance can be eliminated. A high power factor at the input line is assured by operating the buck-boost converters in discontinuous conduction mode. The operation modes, design equations and design steps for the circuit parameters are proposed. A prototype circuit designed for a 70-W metal halide lamp was built and tested to verify the analytical predictions. Satisfactory performances are obtained from the experimental results. | cc2e7bcc5685ff3800883068fee84720841ccd15 | Unpaywall, ScienceParseMerged, IEEE | Engineering, Physics | null | DOI:10.1109/peds.2009.5385693 |
247,452,691 | pes2o/s2ag | v3-fos-license | 2022-03-16T06:18:11.220Z | 2022-03-14T00:00:00.000 | A Novel Local–Global Graph Convolutional Method for Point Cloud Semantic Segmentation | Although convolutional neural networks (CNNs) have shown good performance on grid data, they are limited in the semantic segmentation of irregular point clouds. This article proposes a novel and effective graph CNN framework, referred to as the local–global graph convolutional method (LGGCM), which can achieve short- and long-range dependencies on point clouds. The key to this framework is the design of local spatial attention convolution (LSA-Conv). The design includes two parts: generating a weighted adjacency matrix of the local graph composed of neighborhood points, and updating and aggregating the features of nodes to obtain the spatial geometric features of the local point cloud. In addition, a smooth module for central points is incorporated into the process of LSA-Conv to enhance the robustness of the convolution against noise interference by adjusting the position coordinates of the points adaptively. The learned robust LSA-Conv features are then fed into a global spatial attention module with the gated unit to extract long-range contextual information and dynamically adjust the weights of features from different stages. The proposed framework, consisting of both encoding and decoding branches, is an end-to-end trainable network for semantic segmentation of 3-D point clouds. The theoretical analysis of the approximation capabilities of LSA-Conv is discussed to determine whether the features of the point cloud can be accurately represented. Experimental results on challenging benchmarks of the 3-D point cloud demonstrate that the proposed framework achieves excellent performance. | be991672718ac4039e90faebe07d58d762cfc076 | Medline, Crossref, IEEE, DBLP, ScienceParsePlus | Computer Science | Computer Science, Medicine | DOI:10.1109/TNNLS.2022.3155282 |
240,156,491 | pes2o/s2ag | v3-fos-license | 2021-10-30T13:17:01.918Z | 2021-09-24T00:00:00.000 | Design and Implementation of SDN Routing Optimization Algorithm for Electric Power Communication based on Reinforcement Learning | Routing algorithm of SDN controller has an important impact on the performance of SDN. An optimized routing algorithm for SDN based on reinforcement learning is designed in this paper for the communication requirements of low-delay services in electric power communication networks. The main work includes using a reinforcement learning framework to design state, action and reward, achieve optimal routing strategy selection. Simulation experiments using the 14-node NSFNET topology show effectiveness of the proposed algorithm. | 1f229dd7b7fe84bc5dd812a9a19c07ac5b3fe4b6 | Crossref, IEEE | Computer Science, Engineering | null | DOI:10.1109/CEI52496.2021.9574484 |
258,406,454 | pes2o/s2ag | v3-fos-license | 2023-04-30T15:12:55.020Z | 2023-04-01T00:00:00.000 | Cessation of prosecution: conceptual approaches | The criminal trial represents a specific and complex activity that runs under strict rules that are stipulated by the norms of criminal procedural law. As a result of the criminal trial activity from the part of competent bodies with different tasks, appeared the necessity to divide the criminal procedure into more divisions, called steps of the trial, where complex activities separated into 2 important moments of the process, having different procedural forms and subjects, take place. The time evolution of the criminal process allowed to distinguish 3 stages, every single with a structure, evolution and a different reglementation. The first stage is the prosecution that due to its target and function has a special rol in the criminal procedure. The cessation of prosecution, being a criminal procedural law institution and representing the prosecution, is very important in the procedural activity thanks to its specific features that we are trying to explain in this article. | 145ab5d7542999f1f20c4d8f7a164d32984f8896 | Crossref | Law | null | DOI:10.52507/2345-1106.2023-1.09 |
10,712,148 | pes2o/s2ag | v3-fos-license | 2018-04-03T00:16:28.056Z | 2008-07-01T00:00:00.000 | Differences in ventricular vulnerability, serum enzyme activities, and electrolyte levels between male and female broilers. | Sudden death syndrome (SDS) is one of the most serious diseases of fast-growing broilers. The incidence of SDS may result from a decrease in ventricular function. The purpose of this study was to explore the mechanism of sexual difference in the sensitivity of broilers to SDS by measuring their ventricular vulnerability, serum enzyme activities, and serum electrolyte levels. Results were as follows. 1) Ventricular fibrillation thresholds induced by injection of KCl and by electrical stimulus of male broilers were both significantly lower than those of female broilers (P < 0.05), suggesting that the ventricular vulnerability of male broilers was higher than that of female broilers. 2) Serum lactate dehydrogenase and creatine kinase activities of male broilers were significantly higher than those of female broilers (P < 0.01), but there was not a significant difference in serum aspartate aminotransferase activity between male and female broilers. 3) No significant difference was observed in serum electrolyte levels of potassium, sodium, and chloride between males and females. From these results, we concluded that there is a significant difference between males and females in their ventricular vulnerability and serum enzyme activities, which may result in a higher sensitivity of male broilers to injury of the myocardium by stress and may further result in a sexual difference in sensitivity to SDS. | ef000438a4ea0849b651e2c43875af2b04a533e3 | MAG, Unpaywall, Medline | Agricultural and Food Sciences | Biology, Medicine | DOI:10.3382/ps.2007-00484, MAG:2055472011 |
35,814,748 | pes2o/s2ag | v3-fos-license | 2018-04-03T02:58:48.763Z | 2013-12-01T00:00:00.000 | Comparison of venous glucose to finger-prick glucose in patients with diabetes under hyperbaric hyperoxic conditions: a pilot study. | INTRODUCTION
Blood glucose is commonly measured in diabetic patients undergoing hyperbaric oxygen treatment (HBOT) from a 'finger-prick' capillary sample. Although this method is an accurate reflection of venous glucose under normal conditions it has not been validated under hyperbaric, hyperoxic conditions.
METHODS
Four patients with diabetes mellitus undergoing HBOT had venous blood samples drawn simultaneously with routine capillary samples before, during and immediately after three of four HBOT sessions. The Bland-Altman method of assessing agreement between these two measures was used separately for the three time periods.
RESULTS
The relationship between venous and finger-prick glucose at room air was altered significantly by HBOT. The bias (finger-prick minus venous measurements) was significantly less than zero during the HBOT session but not immediately after completion of the session. Owing to the small sample size, the limits of agreement straddled zero at all time points, although the lower limit was close to zero during treatment (finger measurement appeared to be higher than venous measurement on room air and lower than venous undergoing HBOT).
CONCLUSION
Finger-prick capillary sampling may not be an accurate reflection of venous glucose during HBOT. | d5416c130c28afc3cdb6d6cd2f399359939300a9 | MAG, Medline | Medicine | Medicine | MAG:1802745668 |
231,768,356 | pes2o/s2ag | v3-fos-license | 2021-02-03T06:17:18.732Z | 2021-01-28T00:00:00.000 | Tracheal Intubation‐related adverse events in pediatrics anesthesia in Ethiopia | Tracheal intubation is a common intervention for many pediatric surgical patients. Even though it can be lifesaving, it carries a risk of morbidity and even mortality. Evidence is lacking regarding the adverse events related to pediatric intubation in Ethiopia. This study is aimed to assess the scale of tracheal intubation‐related adverse events with its associated factors in pediatrics surgical patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. | f77c4640866c03c73373a61bc9f55bac405a9497 | Crossref, Medline, MAG, MergedPDFExtraction, Wiley | Medicine | Medicine | DOI:10.1111/pan.14143, MAG:3125671071 |
258,687,242 | pes2o/s2ag | v3-fos-license | 2023-05-16T06:17:07.499Z | 2023-05-15T00:00:00.000 | In silico investigation and potential therapeutic approaches of isoquinoline alkaloids for neurodegenerative diseases: computer-aided drug design perspective | Abstract Microtubule affinity regulating kinase (MARK4) has been proposed as a potential therapeutic target for diabetes, cancer, and neurological diseases. We used a variety of computational studies techniques to examine the binding affinity and MARK4 inhibitory potential of several isoquinoline alkaloids. MARK4 has been associated with tau protein phosphorylation and, consequently, Alzheimer’s disease. The three molecules with the highest binding affinities inside the 5ES1 receptor, according to molecular docking experiments, are isoliensinine, liensinine, and methylcorypalline. Isoliensinine had the highest drug score and drug likeness, coming in at 1.17, while Liensinine and Methylcorypalline came in at 1.15 and 1.07, respectively. The thesis claims that three compounds have a better chance than the others of being identified as therapeutic leads. The bulk of the compounds under investigation didn’t break any of Lipinski’s five rules, especially methylcorypalline, which did and is probably orally active. The majority of the compounds under investigation, particularly Isoliensinine, Liensinine, and Methylcorypalline, show the potential to exhibit drug-like behaviour, which is strongly confirmed by ADMET characteristics estimates. The chemicals Isoliensinine, Liensinine, and Methylcorypalline, especially Methylcorypalline, form the most stable combination with the 5ES1, according to a 100 ns molecular dynamics simulation of these compounds docked inside 5ES1 complexes. Methylcorypalline has a higher binding affinity inside 5ES1, according to additional MM/GBSA experiments using MD trajectories. Overall, research supports the use of the drug development tool methylcolipalin for its ability to inhibit MARK4, which may have implications for the treatment of neurodegenerative diseases. Communicated by Ramaswamy H. Sarma | 12d7e9fddb8f386dcab0e81c97e8c26f4d15c62b | Crossref, TaylorAndFrancis, Medline, ScienceParsePlus | Medicine, Chemistry, Computer Science | Medicine | DOI:10.1080/07391102.2023.2212778 |
2,953,992 | pes2o/s2ag | v3-fos-license | 2017-05-03T07:10:20.516Z | 2010-07-01T00:00:00.000 | Incremental Diagnostic Value of Regional Left Ventricular Function Over Coronary Assessment by Cardiac Computed Tomography for the Detection of Acute Coronary Syndrome in Patients With Acute Chest Pain: From the ROMICAT Trial | Background—The incremental value of regional left ventricular function (LVF) over coronary assessment to detect acute coronary syndrome (ACS) is uncertain. Methods and Results—We analyzed 356 patients (mean age, 53±12 years; 62% men) with acute chest pain and inconclusive initial emergency department evaluation. Patients underwent 64-slice contrast-enhanced cardiac computed tomography before hospital admission. Caregivers and patients remained blinded to the results. Regional LVF and presence of coronary atherosclerotic plaque and significant stenosis (>50%) were separately assessed by 2 independent readers. Incremental value of regional LVF to predict ACS was determined in the entire cohort and in subgroups of patients with nonobstructive coronary artery disease, inconclusive assessment for stenosis (defined as inability to exclude significant stenosis due to calcium or motion), and significant stenosis. During their index hospitalization, 31 patients were ultimately diagnosed with ACS (8 myocardial infarction, 22 unstable angina), of which 74% (23 patients) had regional LV dysfunction. Adding regional LVF resulted in a 10% increase in sensitivity to detect ACS by cardiac computed tomography (87%; 95% confidence interval, 70% to 96%) and significantly improved the overall accuracy (c-statistic: 0.88 versus 0.94 and 0.79 versus 0.88, for extent of plaque and presence of stenosis, respectively; both P<0.03). The diagnostic accuracy of regional LVF for detection of ACS has 89% sensitivity and 86% specificity in patients with significant stenosis (n=33) and 60% sensitivity and 86% specificity in patients with inconclusive coronary computed tomographic angiography (n=33). Conclusions—Regional LVF assessment at rest improves diagnostic accuracy for ACS in patients with acute chest pain, especially in those with coronary artery disease and thus may be helpful to guide further management in patients at intermediate risk for ACS. Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00990262. | f745e6c75c95a4ff2b3f4f5c0cca294f026617d8 | ScienceParseMerged, WoltersKluwer, Anansi, Medline, MAG, Unpaywall, MergedPDFExtraction | Medicine | Medicine | DOI:10.1161/CIRCIMAGING.109.892638, MAG:2026583645 |
219,694,509 | pes2o/s2ag | v3-fos-license | 2020-06-16T14:25:30.564Z | 2006-08-01T00:00:00.000 | Habitus, Barriers and the [Ab]use of the Science of Interval Training in the 1950s | Exploring the methods used by Franz Stampfl and Percy Wells Cerutty to help their athletes break the barrier of the first four-minute mile, this paper will attempt to unravel some of the myths surrounding the training of great athletes in the 1950s. The training of Stampfl has long been regarded as cold and scientific, whereas the methods of Cerutty relied upon a tacit knowledge of the body derived from the use of distinctive training philosophy – the creed of the ‘Stotan’. In effect the ‘battle’ between the two coaches was seen to be ideological. However, a close examination of the methods employed by both Stampfl and Cerutty highlights that they largely relied upon similar training methods which developed embodied habit, and it was simply where the training took place that was distinct. | 20d003774fa12c021f78ae5b75438b437f87e4c8 | MergedPDFExtraction, TaylorAndFrancis | Education | null | DOI:10.1080/17460260600786971 |
251,473,759 | pes2o/s2ag | v3-fos-license | 2022-08-11T13:08:15.842Z | 2022-03-01T00:00:00.000 | The Impact of Digital Media and Artificial Intelligence on the SMEs in Developing Countries: An Exploratory Desk Study | With the era of globalization and the technological revolution, the significance of digitalization has been increasing as it has been incorporated in all types of enterprises, especially small-medium enterprises. As digitalization has enabled these business corporations to form a strategic mechanism that is allowing these companies modern and technological ways to enact and execute business operations by increased connectivity and collaboration. However, it has been implied that most SMEs are facing enormous challenges in evolving a coherent digital transformation, as it also involves digital media and artificial intelligence. Digital media has a strong impact on SMEs, as it proves beneficial in the growth of the business, increasing brand awareness. The most common challenges faced by the companies are the changes in the internal practices and processes of the company, and the mobilization of the business resources, which requires a large investment. Therefore, the objective of the research is to analyze the impact of digital media and artificial intelligence on the SMEs of developing countries, and the services offered by the digital media and AI to these enterprises. The research is based on a secondary research method, including desk research and an extensive previous literature review, from several data sources. The study provides an insight into the innovative characteristics of digital media and AI on the SMEs, presenting some recommendations to the SMEs to develop means to effectively incorporate digital media and AI. | 133ac4251c8ab00546921beb0233c109b72dbb4b | IEEE, Crossref | Business, Computer Science | null | DOI:10.1109/ICIM56520.2022.00045 |
40,830,424 | pes2o/s2ag | v3-fos-license | 2018-04-03T04:55:29.479Z | 1991-01-01T00:00:00.000 | [Disorders of the hypothalamo-hypophyseal system as a cause of infertility in hyperprolactinemia]. | The purpose of the study was to describe hypothalamopituitary functional status of females with infertility in combination with hyperprolactinemia. To this end, changes in prolactin, LH, FSH and TSH in response to the administration of releasing hormones (Gn--RH and TRH) and the dopamine antagonist metoclopramide were assessed in 28 patients with hyperprolactinemic amenorrhea and 5 normal cycling women. Lactotrophs were found to be resistant to functional tests, the resistance increasing as the prolactin level went up. Gonadotrophic and thyrotrophic response to functional tests, on the contrary, increased with the progress of hyperprolactinemia. A conclusion is drawn that stable hyperprolactinemia is a result of disturbance in lactotrophic receptor apparatus, for which reason lactotrophs are no longer sensitive to dophamine inhibiting effect on prolactin secretion. | d9a5b611458a11f2e2ef60289ee529eabddd0ddb | Medline, MAG | Medicine | Medicine | MAG:2469041580 |
22,871,724 | pes2o/s2ag | v3-fos-license | 2018-04-03T05:21:20.927Z | 1988-05-01T00:00:00.000 | Breathing dry air causes acute epithelial damage and inflammation of the guinea pig trachea. | Drying and cooling of the airways mucosa caused by respiratory water loss may be responsible for exercise- and hyperventilation-induced asthma. Therefore we designed this study to investigate whether breathing dry air is capable of causing structural changes of the airways mucosa. Anesthetized guinea pigs breathed spontaneously through a tracheostomy either dry (n = 15) or water-saturated (n = 12) air at approximately 38 degrees C for 30 or 60 min, during which time total pulmonary resistance (TPR) was measured. Immediately afterward, the animals were killed and the lungs and airways were prepared for histological examination (light microscopy, transmission electron microscopy, and scanning electron microscopy). With dry as well as humid air, there was no change in TPR or in the structure of the main bronchi and lung parenchyma. With humid air the tracheal mucosa was normal in six guinea pigs and exhibited minor changes of the ciliae in eight and localized epithelial damage on light microscopy in the remaining animal. With dry air we found widespread loss of the ciliae on scanning electron microscopy in 10 of 12 animals, associated with detachment or sloughing of the epithelium, subepithelial vascular congestion, edema, and cellular infiltration on light microscopy. Our data demonstrate that a short exposure of the trachea to dry air causes marked epithelial lesions and local inflammation. | a9b355d47e2a0ca9690975aaf855a626647ebee2 | Unpaywall, Medline, MAG | Environmental Science, Medicine | Chemistry, Medicine | DOI:10.1152/JAPPL.1988.64.5.1851, MAG:2119563022 |
257,927,574 | pes2o/s2ag | v3-fos-license | 2023-04-05T13:12:15.511Z | 2023-04-02T00:00:00.000 | Immunoproteasome deficiency results in accelerated brain aging and epilepsy | The immunoproteasome is a central protease complex required for optimal antigen presentation. Immunoproteasome activity is also associated with facilitating degradation of misfolded and oxidized proteins, which prevents cellular stress. While extensively studied during diseases with increasing evidence suggesting a role for the immunoproteasome during pathological conditions including neurodegenerative diseases, this enzyme complex is believed to be mainly inactive in the healthy brain. Here, we show an age-dependent increase in polyubiquitination in the brain of wild-type mice, accompanied with induction of immunoproteasomes, which was most prominent in neurons and microglia. In contrast, mice completely lacking immunoproteasomes (triple-knockout (TKO) mice deficient for LMP2, LMP7 and MECL-1), displayed a strong increase in polyubiquitinated proteins already in the young brain and developed spontaneous epileptic seizures, beginning at the age of 6 months. Injections of kainic acid led to high epilepsy-related mortality of aged TKO mice, confirming increased pathological hyperexcitability states. Notably, the expression of the immunoproteasome was reduced in the brains of patients suffering from epilepsy. In addition, aged TKO mice showed increased anxiety, tau hyperphosphorylation and degeneration of Purkinje cell population with the resulting ataxic symptoms and locomotion alterations. Collectively, our study suggests a critical role for the immunoproteasome in the maintenance of a healthy brain during aging. | 0b3b473677ece5f56509286061249414b7f969b2 | ScienceParsePlus, Anansi, MergedPDFExtraction, BioRxiv | Medicine, Biology | Biology | DOI:10.1101/2023.03.30.534913 |
19,084,624 | pes2o/s2ag | v3-fos-license | 2018-04-03T01:39:35.029Z | 1999-01-01T00:00:00.000 | Cell specific effects of glucocorticoid treatment on the NF-kappaBp65/IkappaBalpha system in patients with Crohn's disease. | UNLABELLED
BACKGROUND/AIMS/PATIENTS: Glucocorticoid treatment is known to reduce nuclear factor-kappa B (NF-kappaB)p65 binding activity and activation in lamina propria cells of patients with Crohn's disease. However, lamina propria cells of glucocorticoid treated patients did not show increased expression of IkappaBalpha, and the hypothesised upregulation of IkappaBalpha by glucocorticoid treatment has not yet been shown in vivo. To investigate whether cells other than lamina propria localised mononuclear cells contribute to increased IkappaBalpha, resection gut specimens from patients matched for Crohn's disease activity index (CDAI) with or without glucocorticoid treatment were studied, and changes in the NF-kappaB/IkappaBalpha system were determined in the lamina propria as well as in underlying submucosal and endothelial cells.
METHODS
Changes in the NF-kappaB/IkappaBalpha system were determined by immunohistochemistry, electrophoretic mobility shift assay, and western blot analysis in resected gut specimens from patients matched for CDAI and van Hees index with or without long term glucocorticoid treatment.
RESULTS
Resection gut specimens from patients with Crohn's disease under glucocorticoid treatment had significantly lower nuclear NF-kappaBp65 levels in mononuclear, epithelial, and endothelial cells than samples from CDAI and van Hees index matched patients not having glucocorticoid treatment. Nuclear NF-kappaBp65 showed a strong positive correlation with both the CDAI (r = 1 for both groups) and the van Hees index (r = 0.605 for untreated and r = 0.866 for glucocorticoid treated specimens). Lower nuclear translocation of NF-kappaBp65 in the glucocorticoid treated group was paralleled by higher IkappaBalpha levels in vascular endothelial cells, but not in infiltrating mononuclear cells.
CONCLUSION
A comparison of resection gut specimens from untreated and treated CDAI matched patients with Crohn's disease showed downregulation of NF-kappaB binding activity and NF-kappaBp65 expression and cell specific induction of endothelial IkappaBkappa expression in the glucocorticoid treated group. As the two groups showed similar disease activity (CDAI, van Hees index), the activation of the NF-kappaBp65/IkappaBalpha system must be only part of the inflammatory cascade leading to the clinical appearance of Crohn's disease. | 634a5ad6a3b83568b41ab95dbeacb944c1d82361 | Medline | Medicine, Biology | Medicine | null |
20,589,924 | pes2o/s2ag | v3-fos-license | 2018-04-03T05:33:25.240Z | 2016-07-19T00:00:00.000 | MDCT Venographic Patterns of Dural Venous Sinus Compromise After Acute Skull Fracture. | OBJECTIVE
Prior studies have shown that skull fractures overlying the dural venous sinuses predispose the patient to an increased risk of dural venous sinus thrombosis (DVST). However, extrinsic compression may also cause sinus compromise and simulate thrombosis. This study set out to evaluate the prevalence and discernibility of DVST versus direct sinus compression in the setting of an overlying skull fracture.
MATERIALS AND METHODS
All initial head MDCT venography examinations performed at a level 1 trauma center over an 8-year period were reviewed (n = 347 patients). The examinations that showed an acute fracture overlying a dural sinus were included for review (n = 107 patients). Three neuroradiologists classified the MDCT venography findings as category 0 (normal), 1 (solely sinus compression), 2 (solely intraluminal thrombus), 3 (mixed sinus compression and DVST), or 4 (indeterminate). Clinical outcomes were assessed at 30-45 days after hospital discharge.
RESULTS
The percentage of patients in each category was as follows: category 0 (31-33% patients), 1 (38-46%), 2 (5-9%), 3 (8-11%), and 4 (8-13%). Categories 2-4 were more likely in the transverse sinus-sigmoid sinus complex (22-30%) and multiple dural sinuses (47-53%) than in the superior sagittal sinus (SSS) (5%). Interobserver reliability was strong (κ = 0.627-0.772; p < 0.0001). Sinus category was associated with fracture site (p = 0.014) but not with clinical outcome (p = 0.236).
CONCLUSION
Sinus compromise is common in patients with overlying skull fractures. Sinus compression can be distinguished from DVST on MDCT venography and is likely more prevalent than previously estimated. The fracture site may in part determine the pattern of compromise because fractures involving the transverse sinus-sigmoid sinus complex or multiple dural sinuses seem more likely to be affected by thrombosis than fractures involving the SSS. | df3de7c1a7ce550a1981381f0ece167668a8b8b2 | Medline, Unpaywall, MAG | Medicine | Medicine | DOI:10.2214/AJR.15.15972, MAG:2488611454 |
215,851,847 | pes2o/s2ag | v3-fos-license | 2020-04-21T04:03:12.917Z | 2019-01-01T00:00:00.000 | Suit of the Youth: �Intentional Pattern-Making� Proof of Concept for Repurposing Apparel | The rate of apparel consumption and disposal has increased over recent years, resulting in an abundance of functional unwanted clothing, much of which ends in landfills. Transforming unwanted goods gives renewed value to these products and is one solution for diverting textile waste. The purpose of this design was to trial the 'repurposing design process' in order to suggest recommendations for continued research. The repurposing level focused in Suit of the Youth was intentional pattern-making, which involves deconstructing a garment and developing new patterns that are purposefully drafted and cut to utilize available fabric to ultimately produce a minimal waste new design. Original materials included a men's suit jacket and slacks. Silhouette inspiration was influenced by activewear and patterns were created and placed to feature original garment components such as pockets and belt loops. Control of excess material was addressed through pleats, flanges, and darts. | 1c7ca1de8ad5ca506defc4e52dc0fd62d2f9a7aa | Crossref, Unpaywall, MAG | Art | Computer Science | DOI:10.31274/ITAA.8377, MAG:3012580738 |
155,179,897 | pes2o/s2ag | v3-fos-license | 2019-05-17T14:41:26.791Z | 2012-04-01T00:00:00.000 | Self-propagating growth of science and technology: papers and patents of selected Asian economies | This is done by studying the innovation system that has been created around mainly sugarcane and ethanol production in São Paulo State, Brazil. The dissertation illustrates that natural resources must be conceptualised as non-finite, endogenous and dynamic, and that natural resource-based industries can be proactive participants in processes of development that involve an increasing division of labour, diversification, complexity and structural change. The resource curse is not really about natural resources but about learning – or the absence of it. Natural resources do not make countries poor, but weak innovation systems do. Further, there is no a priori reason to expect that natural resource-based industries can not lead development. In the learning economy the international unequal distribution of learning capabilities is the main factor behind differences in wealth and poverty. There is a ‘learning gap’ between developed countries and less developed countries. For less developed countries the only way to close this ‘gap’ is by learning to learn – this can be rephrased as building learning capabilities. Since learning and capability building are systemic processes, building innovation systems is the only way to beneficially participate in the learning economy. Still, the application of the innovation system approach to less developed countries is limited and a broadly-accepted theoretical framework to build innovation systems is yet to emerge. This dissertation presents a framework for such analysis and looks at how and under which circumstances a sugarcane-based innovation system was evolved in Brazil. In the framework the concept of ‘interactive learning space’ is central. It is complemented by a process approach, where focus is on seven key processes that are thought to be of general importance in innovation systems. These concepts represent complementary tools to grasp structural dynamics and process dynamics, respectively, and in turn their interaction. The empirical analysis showed that formation and growth of the innovation system was a result of a combination of learning capabilities, learning opportunities and demand structure that interacted with ‘external’ events. This generated causal chains of events where key processes were stimulated by institutional, organisational and technological innovation. The case study supports the ‘gardening doctrine’ which states that innovation systems can not be built. Instead, innovation systems should be understood as social organisms that must be nurtured, supported and protected to grow – as delicate flowers in a garden. | 6c3761221af09ebbb40ed091c35c1b3a8ec82874 | TaylorAndFrancis, MergedPDFExtraction, Unpaywall, MAG | Economics | Economics | DOI:10.1080/2157930X.2012.663590, MAG:2321955089 |
260,949,129 | pes2o/s2ag | v3-fos-license | 2023-08-17T15:11:39.543Z | 2024-01-01T00:00:00.000 | Spreading Mosaic: An Image Restoration-Inspired Social Rumor Propagation Model | This article draws inspiration from deep learning image restoration technology. If users involved in the rumor topic are regarded as pixels in an image, the uncertainty of user behavior is similar to the ambiguity of pixels in a mosaic image. The prediction of user behavior is influenced by the user and neighboring friends. Similarly, the recovery of mosaic image pixels is also influenced by these pixels and neighboring pixels. Thus, during rumor propagation, the prediction of user behavior is equivalent to the restoration of pixels in the mosaic image. Based on this inspiration, this study proposes a rumor propagation prediction model based on image restoration technology. First, we propose the concept of topic images and design the rumor2pixel algorithm to pixelate the topic of rumor propagation. Second, through the Generative Adversarial Network model, fuzzy pixels in the “rumor topic image” are compensated to learn more realistic rumor propagation trends. Finally, a dynamic approach for predicting the propagation of rumor and countering it based on evolutionary game theory is proposed, named Rumor-DPM (rumor dynamic propagation model). This approach is focused on reconstructing rumor images while taking into account the conflict between rumors and anti-rumors as well as its timeliness. The experimental findings demonstrate that this strategy can more accurately depict the internal dynamics between rumors and anti-rumors and effectively and successfully improve the ability to forecast user behavior throughout the rumor-propagation process. | 779c66384bf9bdc2ddbc302e6bba5a5d482b8769 | IEEE, DBLP, ScienceParsePlus, Crossref | Computer Science, Sociology, Psychology | null | DOI:10.1109/TMM.2023.3305095 |
172,040,856 | pes2o/s2ag | v3-fos-license | 2019-06-01T13:15:40.123Z | 2018-06-16T00:00:00.000 | Peter Lombard on God’s Knowledge and Its Capacities: Sententiae, Book I, Distinctions 38-39 | The global Peter Lombard research reinaugurated in 1990s has resulted in a number of recent publications, but the Master of the Sentences’ theology proper is partially underreseached. In particular, a more detailed exposition of the distinctions 35-41 of his Book of Sentences is needed in order to clarify his doctrine of God’s knowledge and its relation to the human free will. The article builds on the earlier established evidence that, for Peter Lombard in distinctions 35-38, God’s knowledge, in general, is not causative, although some causative power has to be ascribed to God’s knowledge of the good. The last part of distinction 38 and the content of distinction 39 further analyze the capacities and functionalities of the divine omniscience and explain how it interacts with acts of human will. The key question here deals with the problem of alternative states of affairs: whether something may be otherwise than God foreknew. As it is shown, Master Peter agrees that it is possible for created things and events to be otherwise than they are, but insists that God’s knowledge must be in any case exhaustive and infallible. He uses a number of logical tools to defend the thesis about God’s perfect knowledge and the possibility of things happening otherwise, but lacks strict definition of the notion of “possibility” used here. The study concludes that in few cases Lombard’s posse could mean a potency or a simple logical possibility, or the diachronic contingency, but the overall theological statement is clear: potentially, God’s knowledge can be different or include alternative state of affairs but it cannot change. | 5a597352b51f196cd66d08e11c7dc9e9cb6ffb36 | Crossref, Unpaywall, MAG | Philosophy | Philosophy | DOI:10.22240/SENT37.01.006, MAG:2808347157 |
259,807,206 | pes2o/s2ag | v3-fos-license | 2023-07-12T16:39:15.686Z | 2023-06-08T00:00:00.000 | The age of automation: what skills do employees need to stay relevant? |
Purpose
This viewpoint paper envisions the key competencies that employees should cultivate to thrive amidst the age of automation.
Design/methodology/approach
This paper synthesises recent academic and contextual papers on the topic of workplace automation, alongside the author’s practical knowledge as a Global Program Manager for Robotic Process Automation projects in an S&P 500 company.
Findings
Four skill building blocks are created which will help employees stay relevant in the age of automation: process engineering, automation technology, self-leadership and humanistic.
Originality/value
In this new era of automation, the skills of today will no longer be sufficient for employees to remain competitive in future. This paper contributes to literature by envisioning and presenting four skill blocks that could serve as a blueprint for human resources officers and executives to create the future learning plans and hiring strategies of their organisations, as they grow along the automation maturity curve.
| e09c5c1929ee703c7b1aaf03c76c31994e2c2fe5 | Crossref | Business | null | DOI:10.1108/shr-05-2023-0030 |
36,685,494 | pes2o/s2ag | v3-fos-license | 2018-04-03T03:50:09.862Z | 1999-12-01T00:00:00.000 | The temporal dynamics of visual search: evidence for parallel processing in feature and conjunction searches. | Feature and conjunction searches have been argued to delineate parallel and serial operations in visual processing. The authors evaluated this claim by examining the temporal dynamics of the detection of features and conjunctions. The 1st experiment used a reaction time (RT) task to replicate standard mean RT patterns and to examine the shapes of the RT distributions. The 2nd experiment used the response-signal speed-accuracy trade-off (SAT) procedure to measure discrimination (asymptotic detection accuracy) and detection speed (processing dynamics). Set size affected discrimination in both feature and conjunction searches but affected detection speed only in the latter. Fits of models to the SAT data that included a serial component overpredicted the magnitude of the observed dynamics differences. The authors concluded that both features and conjunctions are detected in parallel. Implications for the role of attention in visual processing are discussed. | 5930c685291027cc362cccfca6fc3de9cba8a6de | Unpaywall, Adhoc, MAG, Medline, MergedPDFExtraction, ScienceParsePlus | Psychology | Psychology, Medicine | DOI:10.1037//0096-1523.25.6.1517, MAG:2084737041 |
257,383,799 | pes2o/s2ag | v3-fos-license | 2023-03-08T16:06:50.090Z | 2023-03-06T00:00:00.000 | Till and Keep and God’s Indwelling | This article proposes to restore the understanding of Genesis 1-2 not as an innocent prelude for the Fall, but as the blueprint for the unfolding of God’s plan for the created world. In this context, the idea that humankind was given the image of God is articulated with the instructions given by God in paradise: naming the animals (Gn 2:19), tilling and keeping the soil (Gn 2:15), multiplying, and filling and mastering the Earth (Gn 1:28). Such tasks would have the function of guiding the human development towards the likeness of God, while contributing at the same time to Earth’s development, according to the model furnished by the garden of Eden, arguably meant to be extended and multiplied. The final objective of such efforts would be to prepare the Earth for God’s indwelling. The Parable of the Ten Virgins (Matthew 25:1–13), along with the Parable of the Faithful Servant (Matthew 24:42–51; Mark 13:34–37; Luke 12:35–48) could be said to warrant such interpretation. | 7ff9c9ebdd8cefb5a96d4a484c8a409d833eff1f | Crossref | Philosophy | null | DOI:10.14712/23363398.2023.6 |
14,022,692 | pes2o/s2ag | v3-fos-license | 2016-11-07T22:24:27.530Z | 2016-03-01T00:00:00.000 | Partition Dependence and Carryover Biases in Subjective Probability Assessment Surveys for Continuous Variables: Model-Based Estimation and Correction | As probability elicitation becomes widely used, methods other than one-on-one interviews are being used to elicit expert probabilities. This paper considers biases that may arise when probabilities are elicited in an online or workbook setting. We develop a prescriptive model in which the elicited probability is a convex combination of the expert’s underlying probability with elements of partition dependence and two anchors arising from responses to previous questions (“carryover” bias). Our model, applied to two data sets, allows us to estimate the amount of the various biases in a set of elicited probabilities from experts. We find that both the format of the questions—whether they appear on the same or separate pages/screens—and the ordering of the questions can affect the amount of bias. Our research addresses biases in the presence of multiple anchors and provides guidance on manipulating the availability of anchors. The results demonstrate the persistence of anchoring even with careful questionnaire design; thus, the proposed model-based methods are useful to suggest corrections for the resulting biases. | bedb492602409e9c069a96baf33e5d8965867959 | Anansi, Grobid, ScienceParseMerged, DBLP, Crawler, MAG, Unpaywall | Economics, Mathematics | Computer Science | DOI:10.1287/DECA.2015.0323, MAG:2193583766 |
154,683,492 | pes2o/s2ag | v3-fos-license | 2019-05-16T13:03:37.317Z | 2006-06-01T00:00:00.000 | Industrial Legislation in 2005 | The federal government’s WorkChoices reforms - finally passed by both houses of Parliament in December 2005 - dominated legislative development in the industrial relations field in 2005. This report digests the main features of the extensive changes wrought by this legislation, including the ‘hostile takeover’ of the State systems, the establishment of a new wage-fixing body, changes to workplace bargaining, more draconian controls on industrial action, and the changes to unfair dismissal protection. A constitutional challenge to this legislation has been lodged by several State governments. The outcome of this challenge will not be known for some time. | c663f2095d4e9beef7f3d88ad235564ca91897fe | MAG, Sage, Unpaywall | Law, Business, Political Science | Economics | DOI:10.1177/0022185606064789, MAG:2068046708 |
9,800,540 | pes2o/s2ag | v3-fos-license | 2018-04-03T00:16:20.802Z | 2011-01-01T00:00:00.000 | [Liver and serum glutathione concentration and liver hydrogen peroxide in rats subchronically intoxicated with chlorfenvinphos--organophosphate insecticide]. | BACKGROUND
Toxicity of organophosphate insecticides is mainly due to the inhibition of acetylcholinesterase (AChE). However organophosphate insecticides in acute as well as in chronic and subchronic intoxication may lead to oxidative stress causing enhancement of lipid peroxidation and changing the activities of antioxidative enzymes and concentration of non-enzymatic antioxidant. For this reason the aim of the work was to estimate glutathione and hydrogen peroxide levels in the liver, as well as the concentration of total glutathione in serum of rats in subchronic intoxication with chlorfenvinphos.
MATERIALS AND METHODS
The animals received chlorfenvinphos, intragastrically with use of a stomach tube, at a one daily dose of 0.3 mg/kg/day for 14 or 28 days. For biochemical determinations BIOXYTECH GSH-400 and BIOXYTECH H2O2-560 Assay kit, OXIS International, Inc., Portland, U.S.A. (reduced glutathione and hydrogen peroxide), and Glutathione Assay Kit, Cayman Chemical Company, U.S.A. (determination of serum total glutathione level) were used.
RESULTS
Chlorfenvinphos administration resulted in a decreased level of reduced glutathione in liver accompanied by an increase in liver hydrogen peroxide and serum total glutathione concentrations. The observed changes were more pronounced after 28 days of intoxication.
CONCLUSIONS
The common use of organophosphate insecticides results in the environmental pollution, therefore, the decreased liver glutathione level is an additional risk factor for people treated with different medicine (e.g., paracetamol). | a90bda79c816b2ad251af826ea5112973b8f9ed2 | Medline, MAG | Environmental Science, Medicine | Chemistry, Medicine | MAG:2411059044 |
24,136,190 | pes2o/s2ag | v3-fos-license | 2018-04-03T06:04:15.092Z | 1991-02-01T00:00:00.000 | Acute, reversible tricuspid insufficiency: creation in canine model. | Relatively few methods have been described for the creation of valvular insufficiency in an animal model. Those presented involve limitations such as permanent destruction of the valves or lack of control over the degree of regurgitation produced. We describe a method of acute reversible tricuspid insufficiency that can be easily created and controlled in anesthetized dogs. The model employs a wire spiral that is advanced through the atrioventricular canal from the right atrium. The spiral causes regurgitation by preventing complete apposition of the valve leaflets while permitting retrograde flow to occur through the spiral lumen. The degree of regurgitation can be controlled by the use of spirals of different sizes. Creation of tricuspid insufficiency is demonstrated by the onset of right atrial pressure V waves, a "ballooning" of the right atrium during ventricular systole, palpation of an atrial thrill, or by color Doppler echocardiography. In 14 dogs, right atrial pressure increased from a control value of 9 +/- 3 (mean +/- SD) mmHg to 10 +/- 3 and 12 +/- 3 mmHg, respectively, with spirals of 1.5 and 2.2 cm in diameter (both P less than 0.05). With the 2.2-cm spiral, aortic blood pressure decreased from a control value of 104 +/- 20 to 83 +/- 17 mmHg (P less than 0.05), and cardiac output decreased from 73 +/- 26 to 59 +/- 19 ml.min-1.kg-1 (P less than 0.05). This model is reversible, allows repeated trials of various grades of regurgitation, does not require ventriculotomy, and is relatively nonarrhythmogenic. | f6220a42dc94b58d69cb2604820b02c152985e90 | Unpaywall, MAG, Medline | Medicine, Biology | Medicine | DOI:10.1152/AJPHEART.1991.260.2.H638, MAG:2208850997 |
43,454,854 | pes2o/s2ag | v3-fos-license | 2018-04-03T05:34:54.525Z | 2013-10-25T00:00:00.000 | Remarkable biomimetic chemoselective aerobic oxidation of flavano-ellagitannins found in oak-aged wine. | Under the auspices of Bacchus! Acutissimins, natural flavano-ellagitannins, occur in oak-aged wine as a result of a diastereoselective condensation reaction of the flavan-3-ol catechin, a component of grapes, with the C-glucosidic ellagitannin vescalagin, found in oak. The acutissimins are further converted into natural mongolicains and analogues of camelliatannin G in a remarkably chemoselective fashion by simple aerobic oxidation. | 065e6eb1635b1b6da2f2aed110fb5319498a51dd | Unpaywall, MAG, Medline | Chemistry | Medicine, Chemistry | DOI:10.1002/anie.201305839, MAG:1987210153 |
37,847,155 | pes2o/s2ag | v3-fos-license | 2018-04-03T04:08:11.427Z | 2015-04-01T00:00:00.000 | Healing of implants installed in over- or under-prepared sites--an experimental study in dogs. | OBJECTIVE
To study bone healing at implants installed with different insertion torques.
MATERIAL AND METHODS
In six Labrador dogs, all mandibular premolars and first molars were extracted. After 4 months of healing, flaps were elevated, and two implant sites were prepared at each side of the mandible. In the right side of the mandible, the distal sites were prepared conventionally, while the mesial sites were over-prepared by 0.2 mm. As a consequence, a final insertion torque of ~30 Ncm at the distal and a minimal insertion torque close to 0 Ncm at the mesial sites were obtained. In the left sides of the mandible, however, the recipient sites were underprepared by 0.3 mm resulting in an insertion torque of ≥ 70 Ncm at both implants. Cover screws were applied, and flaps sutured to fully submerge the experimental sites. After 4 months, the animals were sacrificed and ground sections obtained for histological evaluation.
RESULTS
The mineralized bone-to-implant contact was in the range of 55.2-62.1%, displaying the highest value at implants with ~30 Ncm insertion torque and the lowest value at the implant sites with close to 0 Ncm insertion torque. No statistically significant differences were revealed. Bone density was in the range of 43.4-54.9%, yielding the highest value at implants with ≥ 70 Ncm insertion torque and the lowest at the implant sites with close to 0 Ncm insertion torque. The difference between the sites of ~30 Ncm and the corresponding ≥ 70 Ncm insertion torque reached statistical significance.
CONCLUSIONS
Similar amounts of osseointegration were obtained irrespective of the insertion torque applied. Moreover, implants installed in sites with close to 0 Ncm insertion torque may properly osseointegrate as well. | 22f49a78f95f30ea7ef0f16418bf474f6b5ef30d | MAG, Medline, Unpaywall | Medicine, Materials Science | Materials Science, Medicine | DOI:10.1111/clr.12390, MAG:2086254828 |
45,703,455 | pes2o/s2ag | v3-fos-license | 2018-04-03T06:09:46.614Z | 2010-09-01T00:00:00.000 | Toward a Conceptual Framework for Biology | Science progresses faster when researchers operate within an explicit framework of concepts and theories, but currently biology has no explicit, overarching conceptual framework and few general theories. The single general theory currently recognized is that of evolution, which was put forth by Charles Darwin 150 years ago. Recently, Scheiner and Willig (2008) explicated a similarly general theory of ecology. In this paper, using the theory of evolution as an exemplar, I discuss the nature of theory in biology and put forth an overarching theory, as well as new general theories for cells, organisms, and genetics. Along with the theories of evolution and ecology, these constitute a general conceptual framework for the biological sciences. This framework reveals linkages among the various parts of biology, makes explicit the assumptions behind more narrow theories and models, and provides new insights into the structures of biological theories. This framework can also be used as a teaching tool, moving the teaching of biology beyond the transference of a vast compendium of facts. My hope is that this essay will lead to a vigorous discussion and debate across all of biology about the nature and structure of its theories. | 600914576d9127745b1370bf4bc7b27b96b95f2c | Unpaywall, MAG, Medline, UChicago, MergedPDFExtraction | Biology, Philosophy | Medicine, Biology | DOI:10.1086/655117, MAG:1979656166 |
213,491,244 | pes2o/s2ag | v3-fos-license | 2020-01-09T09:22:24.408Z | 2019-07-20T00:00:00.000 | Visualization of the core of a modified Amyloid-β polymorph with MicroED | Affiliations: Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, USA Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA UCLA-DOE Institute, University of California, Los Angeles, Los Angeles, CA, USA Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, CA, USA Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA, USA. Department of Physiology, University of California, Los Angeles, Los Angeles, CA, USA | b2cfba1051e493674871fbfa17e399ecfee48e92 | Unpaywall, MergedPDFExtraction, Crossref, Anansi, MAG | Chemistry, Biology | Chemistry | DOI:10.1107/s010876731909617x, MAG:2997596219 |
12,534,821 | pes2o/s2ag | v3-fos-license | 2018-04-03T00:31:13.465Z | 1990-03-15T00:00:00.000 | Seasonal changes in vasopressin in the brain of the garden dormouse (Eliomys quercinus L.) | The distribution of vasopressin in the brain of the garden dormouse (Eliomys quercinus L.) was examined by immunocytochemistry at different times of the year. In spring‐summer, sexual dimorphism in the density of vasopressin labeling was observed in several areas of the brain. In these regions, such as the lateral septum and the nucleus of the vertical limb of the diagonal band of Broca, male garden dormice showed more vasopressin immunoreactivity than their female counterparts. In autumn‐winter, at the time of hibernation, vasopressin was undetectable in the sexually dimorphically innervated brain regions in males as well as females. In early spring, there was large variation in vasopressin staining in the male brain, whereas the female brain was consistently lacking in vasopressin labeling. In brain regions that exhibited no sexually dimorphic innervation in the summer, vasopressin labeling remained the same throughout the year. The difference in the amount of vasopressin immunoreactivity in males in summer and winter correlated significantly with differences in testes weight. In early spring, because of interindividual variations in the start of sexual activation, testes size does not correlate with the density of vasopressin immunoreactivity. | f5a406b837bd592d5ff9774c22ff5fa762c006ca | MAG, Medline, Unpaywall, ScienceParsePlus, MergedPDFExtraction, Wiley | Biology | Biology, Medicine | DOI:10.1002/cne.902930303, MAG:2083251535 |
255,018,141 | pes2o/s2ag | v3-fos-license | 2022-12-24T16:03:18.674Z | 2022-12-21T00:00:00.000 | Text Structure in Retentive Stage on Semarang Typical Snack Advertisments | The purpose of this paper is to describe the type of text and the text structure of snack advertisements that are in the retentive stage. This paper focuses on the text of Semarang’s typical snack advertisements on the internet. The data collection method used was the observation method, followed by the note-taking technique. Most of the structures of the advertisements are incomplete, i.e. only “Reiteration”, although there is a “Thesis∧Reiteration” structure and an ”Argumentation∧ Reiteration” structure.
Keywords: text structure; retentive stage, advertising text | 2598904f55ddf51f80371b0a0ac70813cc41a38c | MergedPDFExtraction, Crossref, Anansi, ScienceParsePlus | Linguistics | null | DOI:10.18502/kss.v7i19.12437 |
39,434,041 | pes2o/s2ag | v3-fos-license | 2018-04-03T04:31:41.824Z | 1992-01-01T00:00:00.000 | [Importance of morphologic evaluation of carotid lesions in their correlation with cerebral ischemic pathology]. | Authors present a review of 182 atheromatous plaques into the extracranial carotid trunks. Diagnosis of such pathologies were made by Eco-Doppler on 615 patients. Objective was to determinate the emboligen potential of the plaques following structural and functional criteria. Almost all the symptomatic plaques with functional disturbances showed some structural injury with emboligen potential. Two third parts of all the symptomatic diseases hemodynamically no-significant were associated with plaques with emboligen power. On stenosis higher than 70%, functional criterium was more important for study than structural criterium. | 59cf93db218d54d470a132c8f5d215fff0f2b7ad | Medline | Medicine | Medicine | null |
244,696,391 | pes2o/s2ag | v3-fos-license | 2021-11-28T16:49:07.798Z | 2022-01-01T00:00:00.000 | The Ethnographic Vignette as Innovative Tool in Intersectional Social Justice Activist Research | This chapter leverages ethnographic narratives written during the author's year of nearly daily ‘walking tourism' in New York City on the heels of 9/11 as a vehicle to illustrate an innovative approach to community-based research for intersectional social justice purposes. Since the 1990s, the author has employed creatively crafted vignettes as an activist researcher working with alliances of racial, gender, queer, economic, and labor organizations that joined together to conduct progressive intersectional social justice interventions in a conservative Western US state. Here the author extracts pieces of her “New York Stories” for use as vignettes that could be employed in practice-based research as discussion prompts to foster restorative dialogue and participatory action research efforts in community groups and organizations committed to the work of intersectional social justice. | d9561a027d8e1527005f1094df16edfa08639303 | Crossref | Sociology | null | DOI:10.4018/978-1-7998-8479-8.ch004 |
39,478,758 | pes2o/s2ag | v3-fos-license | 2018-04-03T04:34:11.450Z | 2013-07-01T00:00:00.000 | Is cardiac auscultation the Achilles' heel of sports screening? | Recently one of the authors (M. W. Martinez) examined a 17-year-old lacrosse player who experienced an episode of syncope on the playing field. Physical examination revealed a systolic murmur that decreased on squatting. The athlete was diagnosed eventually with hypertrophic cardiomyopathy by 2-D echocardiography and restricted from competitive play. One month earlier, the athlete had been cleared for play by her primary care physician who did not document a heart murmur or any abnormalities on physical examination. The American Heart Association (AHA) recommends 12 elements of preparticipation cardiovascular screening for all competitive athletes. A key element of the screening process is cardiac auscultation. We wondered how effective screening for heart murmurs is in the real world of preparticipation screening. We suspect that episodes like the one mentioned happen far too frequently in the current system of preparticipation examinations. Of the 12 elements recommended by the AHA, 4 of these items refer to physical examination including auscultation for heart murmurs to exclude specifically dy-namic left ventricular outflow murmurs such as hypertrophic cardiomyopathy. Given the recommendation that physical examination is a key one that gatekeepers use for keeping athletes safe, how good are primary care physicians at recognizing basic heart murmurs? | 9bc4ad0a8129e84f84165dbbe0ff5134563433ab | Unpaywall, MergedPDFExtraction, Medline, ScienceParsePlus, Adhoc, MAG | Medicine | Medicine | DOI:10.1249/JSR.0b013e31829a6aa4, MAG:2006296501 |
2,714,358 | pes2o/s2ag | v3-fos-license | 2017-02-22T03:38:27.941Z | 2016-10-01T00:00:00.000 | Impact of Rain, Swell, and Surface Currents on the Electromagnetic Bias in GNSS-Reflectometry | The assessment of the electromagnetic (EM) bias is required to predict the performance of upcoming global navigation satellite systems-reflectometry (GNSS-R) altimetry systems, and its impact in data assimilation climate studies. In previous studies, the EM bias in bistatic GNSS-R altimetry (L-band) was numerically estimated for a wind-driven sea surface height spectrum, including the time-domain variability. In the present study, spectral models for the rain, swell, and surface currents are used to compute a perturbed wind-driven sea surface height spectrum, from which a perturbed three-dimensional (3-D) time-evolving wind-driven sea surface height is computed. The generated sea surface is then illuminated by a right hand circular polarization (RHCP) L-band EM wave, and the wave scattered from each facet is computed from each facet using the physical optics (PO) method under the Kirchhoff approximation (KA). Finally, the EM bias is computed numerically as the height of each patch times the forward-scattering coefficient, divided by the average of the forward-scattering coefficient. The impact of rain on the EM bias is a moderate decrease (in magnitude) due to the damping of the large gravity waves, which is more significant as the wind speed increases. The impact of swell is a small increase (in magnitude) mostly due to the change of the local incidence angles. The impact of currents can be either a moderate increase or decrease (in magnitude), depending on the sense of the current with respect to the wind, due to a change in the surface roughness. | cdc8338b00a2a41797bc3e2fc990b1fdf5a6cd26 | DBLP, MAG, Unpaywall, IEEE, Anansi, ScienceParseMerged | Engineering, Environmental Science, Physics | Computer Science, Physics | DOI:10.1109/JSTARS.2016.2538181, MAG:2508966062 |
270,089,208 | pes2o/s2ag | v3-fos-license | 2024-05-29T15:23:50.834Z | 2024-05-06T00:00:00.000 | Monitoring red wine maturation in oak barrels using 1H NMR-based metabolomics | Wine maturation in oak barrels is a well-known winemaking practice that, among other things, brings roundness and complexity to wine. Studying wine evolution during barrel maturation is crucial to ensure wine quality. Red wines produced in a wine growing estate of the Bordeaux region were monitored after one and twelve months of maturation in oak barrels in the estate’s cellar. Wines were kept in oak casks from three different manufacturers. The evolution of the wine constituents during maturation was monitored by 1H NMR-based metabolomics combined with multivariate statistical analysis. NMR spectra were submitted to targeted and untargeted approaches. The wine maturation effects were thereby monitored and the discriminant metabolites identified. The wines analysed after one month of maturation exhibit higher contents of amino acids, catechin and epicatechin, acetoin and choline than the wines analysed twelve months after maturation; for their part, the latter wines showed higher contents of acetic acid, ethyl lactate, arabinose and glucose. In addition, significant differences were observed between the wines depending on the barrel manufacturers. | 6885226cab84642ad29ba3a3b070afe5b4c62a3d | ScienceParsePlus, Crossref, Anansi | Environmental Science, Chemistry | null | DOI:10.20870/oeno-one.2024.58.2.7465 |
244,246,262 | pes2o/s2ag | v3-fos-license | 2021-11-18T00:03:26.760Z | 2021-09-30T00:00:00.000 | The Implementation of Learning Assessment During The Covid-19 Pandemic on TK Islam Darussalam Palangkaraya | Learning activities during the covid-19 pandemic cannot be seen directly, so teachers are difficult to see the achievements of learning indicators. The purpose of this study is to find out the implementation of learning assessments and obstacles faced by teachers when conducting learning assessments for B1 group students during the covid-19 pandemic at TK Islam Darussalam Palangka Raya. Describing the implementation of learning assessments and obstacles faced by teachers when conducting learning assessments for B1 group students during the covid-19 pandemic at TK Islam Darussalam Palangka Raya. This study uses descriptive qualitative research method, data subjects numbered 3 people (2 teachers of group B1 and Kelapa TK Islam Darussalam). Data collection techniques using observations, interviews and documentation. The results showed that: 1) Assessment of check-up techniques and works carried out on worksheets and anecdotal record assessments were conducted through face-to-face, online and home visits. Assessment of calistung and ummi using monitoring books. The assessment process can be done well, but it cannot be carried out to the maximum.2) The lack of ability of teachers to use digital technology, online learning is sometimes constrained by network connections, worksheet learning carried out at home causes teachers to be unable to see the process of implementation and achievement of learning indicators and the duration of the learning system face-to-face, online and home visits are relatively short causing information on children's learning activities cannot be obtained to the maximum. | 6826cf5c82e05bf514e236806bdfb26a6df63e9c | Crossref, MAG | Education | Psychology | DOI:10.24235/AWLADY.V7I2.8393, MAG:3201916607 |
252,684,989 | pes2o/s2ag | v3-fos-license | 2022-10-04T13:23:31.611Z | 2022-09-28T00:00:00.000 | An analysis of laboratory variability and thresholds for human in vitro ADME/PK methods | Introduction Various in vitro methods are used to measure absorption, distribution, metabolism and excretion/pharmacokinetics (ADME/PK) of candidate drugs and predict and decide whether properties are clinically adequate. Methods Objectives were to evaluate variability within and between laboratories for commonly used human in vitro ADME/PK methods and to explore whether reliable thresholds may be defined. The literature was searched for in vitro data for intrinsic metabolic clearance (hepatocyte CLint), apparent intestinal permeability (Caco-2 Papp), efflux ratio (Caco-2 ER), solubility (S) and BCS-class, and corresponding clinical estimates. In vitro ADME/PK data for three example drugs (atenolol, diclofenac and gemfibrozil) were used to predict human in vivo ADME/PK and investigate whether these would pass a compound selection process. Results and Conclusions Interlaboratory variability is considerable, especially for fu, S, ER and BCS-classification, and on average about twice as high as intralaboratory variability. Approximate mean interlaboratory variability for CLint, Papp, ER and fu (3- to 3.5-fold) appears to be about 2- to 3-fold higher than corresponding interlaboratory variability. Mean and maximum interlaboratory range for CLint, Papp, ER, fu and S are approximately 5- to 100-fold and 50- to 4500-fold, respectively, with second largest range for fu and largest range for S. For one drug, laboratories produced almost 1000-fold different CLint • fu-values. It appears difficult/impossible to set clear clinically useful thresholds, especially for CLint, ER and S. Poor in vitro-in vivo consistency for S and BCS-classification and large portions of compounds out of reach for Caco-2 and conventional hepatocyte assays are evident. Predictions for reference compounds are consistent with inadequate in vivo ADME/PK. Ways to improve predictions and compound selection are suggested. | 0555766fdcb698e42c46ecb1d95e88dfe619f427 | ScienceParsePlus, MergedPDFExtraction, BioRxiv | Medicine | Biology | DOI:10.1101/2022.09.27.509731 |
39,159,689 | pes2o/s2ag | v3-fos-license | 2018-04-03T04:28:25.730Z | 2008-03-18T00:00:00.000 | A naturalistic multicenter trial of a 12-week weight management program for overweight and obese patients with schizophrenia or schizoaffective disorder. | OBJECTIVE
The primary aim of this study was to examine the efficacy and feasibility of a weight control program for overweight and obese patients with schizophrenia or schizoaffective disorder using a large sample across various clinical settings.
METHOD
Psychiatric patients taking antipsychotics participated in a 12-week weight management program at 33 clinical centers across South Korea, and the data for 232 subjects who had a body mass index (BMI) 25 kg/m(2) or above and were diagnosed with DSM-IV schizophrenia or schizoaffective disorder were used in the final analysis. The primary measures of efficacy were changes in body weight and BMI. The study was conducted from December 2005 to July 2006.
RESULTS
These patients showed significant mean +/- SD reductions in BMI (0.98 +/- 1.01 kg/m(2), p < .001) and body weight (2.64 +/- 2.75 kg, p < .001), with moderate compliance, after the 12-week intervention. Diet compliance was the strongest single predictor of weight loss. Although significant differences in BMI reduction occurred between groups classified by clinical setting and compliance, all sex, age, clinical setting, compliance, and initial BMI groups showed significant BMI reductions, which fell between 0.4 and 1.5 kg/m(2).
CONCLUSION
Overall results suggest that a weight management program may be disseminated and adopted by practitioners across settings, resulting in short-term weight loss in schizophrenic and schizoaffective patients. | f77aafc38840ebd8ddb1ad6b3aaba7a8e038e148 | Unpaywall, MAG, Medline | Medicine, Psychology | Medicine | DOI:10.4088/JCP.V69N0406, MAG:1997349099 |
26,620,789 | pes2o/s2ag | v3-fos-license | 2018-04-03T00:49:44.461Z | 2002-01-01T00:00:00.000 | [Comparison of leaf decomposing rate in a headwater stream in Xiangxi River catchment]. | With the litterbag method, the decomposition of leaf of 4 tree species growing in riparian forest in a headwater stream was investigated in 90 d consecutively in Xangxi River catchment. The results showed that the loss rate of dry weight of leaf differed among 4 species. The loss rate of dry weight of Pterocarya insignis and Cercidiphyllum japonicum was 77% and 71%, and shat of Fagus engleriana and Cyclobalanopsis multinervis was 43% and 42%. Using exponential equation, the loss process of dry weight of leaf was modeled. According to the value of constant k, 4 species could be divide into to fast group and medium group. The invertebrate was also collected, and there were 22 species, belong to 3 classes, 6 orders, and 21 families. The quantity of invertebrate differed in each tree species litterbag and different periods. The invertebrate was rich in number and small in body during early time of leaf decomposing, and it was less in number and big in body during middle and late time of decomposing. | b020d81c3d1dc48beeea23e51dffeaeeab726613 | MAG, Medline | Environmental Science | Biology, Medicine | MAG:2393250725 |
2,941,086 | pes2o/s2ag | v3-fos-license | 2018-04-03T03:56:34.894Z | 1990-12-01T00:00:00.000 | A Tribute to Lasègue's Description of Anorexia Nervosa (1873), with Completion of its English Translation | Gull and Lasègue are usually credited with the first description of anorexia nervosa. In general, however, the work of the French neuropsychiatrist has been underestimated, and English-speaking colleagues who refer to Lasègue's writing on ‘hysterical anorexia’ almost exclusively rely on the translation of his French paper, which in 1873 appeared in a British medical journal, the same year as the original publication. However, some important passages had been omitted from the translation, and this has not previously been noted. | 5aab6352fc9bfb85dd370c9f57e72e85941e27fa | Unpaywall, MergedPDFExtraction, Medline, Cambridge, MAG | Psychology, Medicine | Medicine, Psychology | DOI:10.1192/bjp.157.6.902, MAG:2117400096 |
218,620,279 | pes2o/s2ag | v3-fos-license | 2020-05-14T13:03:18.036Z | 2020-05-13T00:00:00.000 | Effects of soil conditions on root rot of soybean caused by Fusarium graminearum. | Fusarium graminearum (Fg) is an important soybean pathogen that causes seedling disease, root rot, pre- and post-emergence damping-off. However, effects of soil conditions on the disease are not well understood. The objective of this greenhouse study was to determine the impacts of soil texture, pH, and soil moisture on seedling root rot symptoms and detrimental effects on seedling development caused by Fg. Fg-infested millet was added (10% v/v) to soil with four different textures (sand, loamy sand, sandy loam, and loam). Soil moisture was maintained at saturation, field capacity or permanent wilting point at soil pH levels of 6 or 8. Seedlings were evaluated 4 weeks after planting for root rot, root length, root and shoot dry weights, leaf area, and Fg colonization (by qPCR). There was a significant interaction between soil moisture and soil texture for root rot assessed visually (P<0.0001). Highest severity (67%) and amount of Fg DNA were observed at pH 6 and permanent wilting point in sandy loam soils. Pot saturation resulted in the lowest levels of disease in sandy loam and loam soils (11.6 and 10.8%, respectively). Reductions in seedling growth parameters, including root length, foliar area, shoot and root dry weights and root tips, relative to the noninfested control, were significantly greater in sandy loam soils. In contrast, there were no significant growth reductions in sand. This study showed that levels of root rot increased under moisture-limiting conditions, producing detrimental effects on plant development. | c315f1b1e37328d8f6a4bff45639dc9967951883 | Crossref, Medline, Unpaywall, MAG | Agricultural And Food Sciences | Biology, Medicine | DOI:10.1094/PHYTO-02-20-0052-R, MAG:3025602081 |
40,777,879 | pes2o/s2ag | v3-fos-license | 2017-05-10T00:05:06.278Z | 2005-10-01T00:00:00.000 | The Relevance of Procedural Utility for Economics | This paper aims at showing the relevance of procedural utility for economics: people do not only care about outcomes, as usually assumed in economics, they also value the processes and conditions leading to outcomes. The psychological foundations of procedural utility are outlined and it is discussed how the concept differs from other related approaches in economics, like outcome utility, outcome fairness or intentions. Institutions at the level of society and fair procedures are shown to be sources of procedural utility, and novel empirical evidence on the role of procedural utility in important areas of the economy, polity and society is presented. | 32be5f2b4f5eb427b20930bd190559b5a6895ac5 | MAG, Anansi, Unpaywall, MergedPDFExtraction, ElsevierPush, ScienceParseMerged | Economics, Psychology, Political Science | Economics | DOI:10.2139/ssrn.840424, MAG:1566719115 |
52,284,197 | pes2o/s2ag | v3-fos-license | 2018-09-18T19:17:03.073Z | 2018-04-12T00:00:00.000 | Reduced-Complexity Trellis Min-Max Decoder for Non-Binary Ldpc Codes | In this paper, a novel algorithm and corresponding reduced-complexity decoder architecture are proposed for decoding the trellis min-max NB-LDPC code. This proposal reduces the number of messages exchanged between check node and variable node as well as the hardware complexity. Thus, the memory requirement and the wiring congestion is decreased, which increases the throughput of the decoder with a negli - gible error-correcting performance loss. A layered decoder architecture is implemented for the (2304, 2048) NB-LDPC code over GF(16) based on the proposed algorithm with a 90-nm CMOS technology. The results show an area reduction of 19.4% for the check node unit, 26.56% for the whole decoder and a throughput of 1396 Mbps with almost similar error-correcting performance, compared to previous works. | 28ea3a478095ae0bec2f87638c61267e37392c64 | IEEE, MAG, ScienceParseMerged, Unpaywall, DBLP, Anansi | Computer Science, Engineering | Computer Science | DOI:10.1109/ICASSP.2018.8462192, MAG:2807101935 |
237,348,857 | pes2o/s2ag | v3-fos-license | 2021-08-30T13:04:54.859Z | 2021-04-03T00:00:00.000 | Paleogenomics of the prehistory of Europe: human migrations, domestication and disease | Abstract A substantial portion of ancient DNA research has been centred on understanding European populations’ origin and evolution. A rchaeological evidence has already shown that the peopling of Europe involved an intricate pattern of demic and/or cultural diffusion since the Upper Palaeolithic, which became more evident during the Neolithic and Bronze Age periods. However, ancient DNA data has been crucial in determining if cultural changes occurred due to the movement of ideas or people. With the advent of next-generation sequencing and population-based paleogenomic research, ancient DNA studies have been directed not only at the study of continental human migrations, but also to the detailed analysis of particular archaeological sites, the processes of domestication, or the spread of disease during prehistoric times. With this vast paleogenomic effort added to a proper archaeological contextualisation of results, a deeper understanding of Europe’s peopling is starting to emanate. | 64dad631016e29ffbb7d11aa0e2afaef5092b5f0 | Medline, MergedPDFExtraction, TaylorAndFrancis | History, Biology | Medicine | DOI:10.1080/03014460.2021.1942205 |
21,659,462 | pes2o/s2ag | v3-fos-license | 2018-05-21T20:56:47.697Z | 2018-05-01T00:00:00.000 | Re: Sexual Harassment | Sexual harassment is widespread and prolific across the human race, mostly of females by males. It is a spectrum, from the worst of criminal behaviour (e.g. rape and murder of strangers, of women and girls) to what might be considered harmless playful banter between the sexes from later childhood and ever after. It does not occur in infancy, and appears to begin as a ‘learned’ phenomenon from later childhood. In his editorial, Isaacs considers sexual harassment occurring of women within our own profession, recognising that almost all examples of sexual harassment involve bullying, abuse of power and greater physical strength by males, often leading to emotional and/or physical harms. He does not mention the biological differences between the sexes. While sexual harassment is apparently learned, not innate, pre-pubertal boys and men are more aggressive than females, have more accidents and commit more violent crimes. While biological differences make males more often the initiators of sexual advances, they are no excuse for predatory or inappropriate behaviour, but any improvements will need to take these differences into account. Isaacs does not mention the importance of co-factors, the worst of which is alcohol. The disinhibiting effect of alcohol is relevant in both promoting and facilitating abuse, and any solution will need to take alcohol into account. Isaacs advocates greater fight-back by women and better behaviour by men. In truth, we really do not know what to do to prevent sexual harassment, but whatever it is, it needs to be on multiple fronts. We must start with teaching children, especially boys, that sexual harassment is unacceptable, like all bullying. As is clear from public health improvements, for example seat belts, pool fences and reducing drink driving, both active measures (sanctions) and passive measures (advocacy) will have to be used. | bebd166e4d70e7e44674f2162164fb260a2bb2f9 | Wiley, MergedPDFExtraction, Medline, MAG, Unpaywall | Psychology | Medicine | DOI:10.1111/jpc.13911, MAG:2803388895 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.