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. Two females and a male were swiping items from a store. When two people, a 24-year old woman and 30 year-old-man, tried to stop the three suspects in the store's entrance, one of the shoplifters sprayed the male victim in the face with an aerosol. Police do not describe what type of chemical was used, but the male was transported to Mercy Hospital.Chicago Police report three business have been targeted in the same shopping district on the 1000 block of South Canal. The cases were reported on November 8th and 9th. They happened at Marshall's, Burlington, and DSW. Police report that two of the cases ended with arrests.Shoplifters targeted the Patagonia store twice during the last week. On Saturday, November 9, five juveniles swiped merchandise and left the store, police reported. Police said all five were arrested and charged with felonies. They range in age from 11-15.Shoplifters targeted the same store a day later, on Sunday, November 10. Two suspects stole merchandise. No arrests have been made in this case.Q: Using Request/Response in REST service I'm currently designing a REST WVF web service in C# that will be used by an MVC website and just confused about one point. Say I have two methods with signature public bool IsEmailAvailable(string email address) {... } public DbUser GetUser(object id) {... } Can I just keep my service interface and implementation as above? Someone has mentioned to me about designing it more like public IsEmailAvailableResponse IsEmailAvailable(IsEmailAvailableRequest request) {... } public GetUserResponse GetUser(GetUserRequest request) {... } What are the pros and cons of implementing it each way? A: This is someone is a clever guy. Remote interface is very important, the second version is more maintainable. You can can add additional params into Request|Response without breaking changes. This is a message based style. As for me, even the second version is not good choice. The second version contains too concrete methods. A remote interface should be based on parametric polymorphism, so this kind of API will be stable and flexible Thus, RESTful api should look like: object Get(object request); object Post(object request); object Put(object request); object Delete(object request); etc.. Unfortunately, WCF doesn't support this kind of interface by default, but we can use the Message instead object and get the same result. Take a look a following article for more details: Building RESTful Message Based Web Services with WCF 20.5 2016 Three more years with Daniel Birnbaum Congratulations, Daniel! You’ve been offered three more years as director of Moderna Museet. How does it feel? It feels great. I’m happy that the government continues to have confidence in me, and for being asked to stay on. And I’m equally pleased that Ann-Sofi Noring, our co-director, wants to go on leading the Museum with me. What will you be doing next? Tomorrow, we open The New Human, an exhibition about what happens to us in a politically volatile world that is entirely permeated with new technology. Some of the works are rather gloomy, by a few of the world’s most famous young artists who use digital technology and moving images. In a few weeks, we’ll be opening a more upbeat show, Yayoi Kusama: In Infinity, the first presentation in Sweden of an enormously popular artist from Japan. This will be the biggest exhibition event of the year. What is the most urgent issue for the Swedish art scene over the coming years? The most crucial issue, as always, is the opportunity for artists in Sweden to develop their artistic practices. And for the public, the important thing, of course, is to show the most urgently relevant art. We are here to make that possible, and we will continue to do our best. It’s also important for art in Sweden to get impulses from abroad. Moderna Museet has always been a forum for international art, and it would be virtually impossible for any other institution to bring some oeuvres to Sweden. Is there anything you would like to say to those who don’t get round to experiencing art? Yes, this is what I would like to say: Give art a chance! I think it will make your lives more exciting. Richer, and more enjoyable! You’ve said that art expands our perspective on the world – could you explain? Recently, a wise person said, science helps us to understand the world. Art, on the other hand, helps us to understand ourselves. That sounded good to me. Still, it’s not just about understanding things. Art can sometimes be confusing. You don’t understand it at all, but you like it anyway. Why does Moderna Museet have so many exhibitions of old American men? In recent years, we’ve actually produced more exhibitions with women artists than men. And not that many were Americans. But, of course, we did show Cindy Sherman not too long ago. And Louise Bourgeois did eventually become a US citizen. Our collection includes many works by fantastic American artists who are not only old but regrettably dead: Robert Rauschenberg, Andy Warhol, and many others. Yes, now that you mention it: it’s probably high time to exhibit a really old American man. I would be delighted to invite John Baldessari from Los Angeles to Sweden. He’s not just old but also brilliant. What do you mean by “Art in a Larger World”? For many years, museums in Europe have limited their exhibitions to Western artists. But things have changed, and we now show artists who build bridges between traditions and continents. Last summer, we exhibited artists from countries such as Argentina, Lebanon and South Africa, and last summer’s exhibition After Babel was about the many languages in contemporary art. An observant visitor will also discover that a lot of great art is created by artists who live in Sweden but have roots in traditions beyond the Nordic region. Recently, we featured the Kurdish painter Madhat Kakei, along with Meriç Algün-Ringborg from Turkey, who both live in Sweden. What makes Moderna Museet one of the best art museums in the world? A good museum is a place that engages in both the present and the past. Our collection is an incredible resource, and Moderna Museet truly continues to expand it in a very dynamic way. The last few years have been sensational with regard to the addition of new works by key Swedish artists, as well as by Louise Bourgeois and Sigmar Polke, Cindy Sherman and Gabriel Orozco, Rosemarie Trockel and Jeff Wall, and hundreds of other artists. Yes, even modernists like Paul Klee and Pablo Picasso. I doubt that any other publicly financed museum in Europe has been collecting at our level in recent years. All this has been made possible with support from the Friends of Moderna Museet, who understand that by donating a masterpiece to Moderna Museet you are giving it to yourself and to everyone else. The works in our collection belong to us all. And the fact that so many people have understood this, has made Moderna Museet one of the most dynamic museums in the world.Hello, all. In case you missed the last couple of updates, about two weeks ago, Gatsbys were sent back to FocusWorks EDC due to varying degrees of wobble. They were returned to me yesterday afternoon and since then, I’ve been prepping them for the drop. All the HC3zs in the spinners felt dirty when I got them, so I spent about 4 hours cleaning them, but to no avail. Damage was probably incurred from crossing the border twice. I’ve ordered new ones from FZEssentials, and those will be here this week, in time for me to swap them out. In the meantime, I’ve been switching the gritty HC3zs out with a clean bearing to accurately test balance. Before Jordy shipped the spinners back, I asked him if they would pass the lift test. He said he has never conducted that test in thousands of spinners sold, but they passed his tests and were spinning smoothly – therefore, they should pass the lift test as well. And like he said, almost all are spinning smoothly at all speeds. However, all of them do favor one side when lifted straight up. At this point, I’ve literally quadruple-checked each one to make sure that the spin is unaffected by the overall balance. I won’t be selling the couple that are still wobbly. And unfortunately, I don’t have the tools to balance them myself. This isn’t Jordy’s fault, since he did take them back and made sure they passed his tests. I didn’t clarify my expectations when we started, which I should have done. Thank you all for following along. It’s been a long journey, but we are almost there. I’ll post drop details soon.Radiation-absorbed dose from 201Tl-thallous chloride. Revised radiation dosimetry estimates for 201Tl-thallous chloride have been developed using new data specifically acquired to address the issue of testicular uptake of this agent and through reevaluation of extant data for biodistribution in other organs. Quantitative testicular scintigraphy data of sequestered testes (body-
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pdf`: recall for each size and each attribute, respectively\n", " - `judge/products/detection_report.json`: the output of evaluation API described above\n", " - `judge/products/explore_det.html`: performance for each conbination of attributes and each size\n", "\n", "Notes:\n", "\n", " > If you are using trained models and validation set, you may result in a higher performance than paper. The reason may be our models are trained on TRAIN+VAL, while you are using validation set as testing set." ] }, { "cell_type": "code", "execution_count": null, "metadata": { "scrolled": true }, "outputs": [], "source": [ "!git submodule update --init --recursive\n", "!cd../judge && python3 detection_perf.py" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "#### Draw detections on images\n", "\n", "We show TPs in <font color=\"#0f0\">**green**</font>, and show FPs in <font color=\"#ff0\">**yellow**</font>. For each image, we draw most confident DTs, and set $num(TPs) + num(FPs) = num(GTs)$.\n", "\n", "We will output the following files in this step:\n", "\n", " - `judge/products/printtext-drawing/*.pdf`" ] }, { "cell_type": "code", "execution_count": null, "metadata": {}, "outputs": [], "source": [ "!cd../judge && python3 draw_detection_text.py" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "## Appendix: Details to the evaluation API\n", "\n", "Our Python evaluation API in `pythonapi/eval_tools.py` and C++ evaluation API `cppapi/eval_tools.hpp` work as follows, which is similar to PASCAL VOC.\n", "\n", " 1. Check the detection (DT) file has the same number of lines as the ground truth (GT) file. Otherwise, return error.\n", " 1. Check each line of the DT file is valid JSON, and conform to the submission format. Otherwise, return error.\n", " 1. Use the ignore list (IG) in the annotations.\n", " 1. Remove non-Chinese character instances from GTs.\n", " 1. For each size, for any given confidence score $c_0$, we deal with DTs, GTs, and IGs of each image in the following steps, respectively.\n", " 1. Move GTs which are not fit current size range to IG. (For size 'all', this step always has no effect.)\n", " 1. DTs which confidence score is less than or equal to $c_0$ are removed.\n", " 1. Match DTs with GTs greedily. We consider DTs in score order. For each DT, GTs are ordered by $IOU(DT, GT)$ in descending order. matched DTs are true positives (TPs).\n", " 1. Remove unmatched DTs which can match IGs. They will have no effect on the evaluation.\n", " 1. Remove unmatched DTs which are not fit current size range. (For size 'all', this step always has no effect.)\n", " 1. Remaining DTs are FPs, Remaining GTs are false negatives (FNs).\n", " 1. For each size, we compute metrics in following steps, respectively.\n", " 1. Take all TPs, FNs, and FPs to compute `AP`.\n", " 1. For each character category, take TPs, FNs, and FPs in the specified category to compute average precision (AP). Compute mean of these APs weighted by the number of character instances in the corresponding category, denote the mean value as `macro-mAP`, also called `mAP`.\n", " 1. For each image, we take a minimum confidence score $c_0$ which leads to $num(TPs) + num(FPs) \\leq num(GTs)$, respectively. Then,\n", " 1. for each attribute, compute `recall` by counting TPs which $score > c_0$ and belong to the specified attribute for each image, respectively.\n", " 1. for each character category, compute `recall` by counting TPs which $score > c_0$ and belong to the specified category for each image, respectively.\n", " 1. For each image, take TPs, FNs, and FPs in the specified image to compute AP. Compute the mean of these APs, denote this mean value as `micro-mAP`.\n", "\n", "When matching a DT with a GT, we require they have the identical character category, and $IOU(DT, GT) > 0.5$. When matching a DT with a IG, we require $\\exists ig \\subseteq IG$, s.t. $IOU(DT, ig) > 0.5$. Of which $IOU(A, B) = \\frac{Area(A \\cap B)}{Area(A \\cup B)}$. Otherwise, they are not matched.\n", "\n", "When computing an AP, for any confidence score $c_0$, we compute precision by taking the maximum of each precision at confidence score $c \\geq c_0$.\n", "\n", "Computation steps above are inefficient. We write more efficient code which don't follow these steps but results in the same results for any legal detection files.\n", "\n", "Notes:\n", "\n", " > Python API and C++ API may generate slightly different results due to floating-point precision, the difference is always less than 0.0000001%. We officially approve the results of C++ API.\n", " >\n", " > Even if some DTs have the same confidence score, our evaluation API produces a certain reproducible result." ] } ], "metadata": { "kernelspec": { "display_name": "Python 3", "language": "python", "name": "python3" }, "language_info": { "codemirror_mode": { "name": "ipython", "version": 3 }, "file_extension": ".py", "mimetype": "text/x-python", "name": "python", "nbconvert_exporter": "python", "pygments_lexer": "ipython3", "version": "3.6.3" } }, "nbformat": 4, "nbformat_minor": 2 } package com.dou361.update.download; import com.dou361.update.ParseData; import com.dou361.update.UpdateHelper; import com.dou361.update.bean.Update; import com.dou361.update.listener.UpdateListener; import com.dou361.update.type.UpdateType; import com.dou361.update.util.HandlerUtil; import com.dou361.update.util.InstallUtil; import com.dou361.update.util.NetworkUtil; import com.dou361.update.util.UpdateSP; /** * ======================================== * <p/> * 版 权：dou361.com 版权所有 （C） 2015 * <p/> * 作 者：陈冠明 * <p/> * 个人网站：http://www.dou361.com * <p/> * 版 本：1.0 * <p/> * 创建日期：2016/10/13 9:56 * <p/> * 描 述：无网络工作类 * <p/> * <p/> * 修订历史： * <p/> * ======================================== */ public class UpdateNoUrlWorker implements Runnable { protected UpdateListener checkCB; protected ParseData parser; protected String requestResultData; public void setRequestResultData(String requestResultData) {
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needing to set 2 cookies: initial temp cookie to check against, and then your 'dc_tempusername' cookie. You could even go as far as using Browscap to check against known bots: https://github.com/browscap/browscap-php http://browscap.org/ You'll need to be able to define browscap in your php.ini namespace ActiveLogin.Authentication.BankId.AspNetCore.Azure { public class ClientCertificateFromAzureKeyVaultOptions { public bool UseManagedIdentity { get; set; } public string? AzureAdTenantId { get; set; } public string? AzureAdClientId { get; set; } public string? AzureAdClientSecret { get; set; } public string? AzureKeyVaultUri { get; set; } public string? AzureKeyVaultSecretName { get; set; } } } “Though I’ve never met you And we’ve spoke not a word I’ll never forget you Through the stories that I’ve heard” – “Unknown Brother” by The Black Keys August 26, 1987 – November 21, 2011 I could not write this post yesterday. I was too pissed off. Too sad. Too hurt. It took me awhile to gather my thoughts on Greg Halman. I’m not sure if I can really pen it all out but I’ll try my best. Greg Halman was a product of the Seattle Mariners since he was a young teenager. He came to this country as the rawest of the raw in regards to baseball prospects. You don’t have to look too far into your Google search to know not many players come from The Netherlands; Halman bucked that trend. For a minor league system that struggled for much of the 2000’s, the Seattle Mariners did great by landing Halman. June 26, 2004 to be exact. Two days after I turned 21 years old. Yes, I still had (and still have) much ahead in my life but Greg Halman was two months to the day shy of turning 17. Think about that. 16 years old and signing with a professional baseball team. The odds were against him and he proved them wrong. One of my most knowledgeable and creative minded friends Kenny Stein (@casetines) and I salivated at talking about the Mariners minor league system. It became “our thing”. Many friendships grow for various reasons, but with Kenny and I, talking minor league baseball has always been one of those things. Simply put, we both loved Greg Halman. Halman grew through the Mariners farm system; he was home fed. The incredibly gifted 6‘4, 200-pounder spent seven seasons in the organization. For me, Halman “arrived” on the scene with my favorite minor league team, the Everett AquaSox. In 2007, he smacked 16 HR in 62 games with Everett and by all accounts, proved himself worthy of “prospect status”. But 2008 is when I really had the sunshine and lollipops dance in my head. Greg was the Mariners’ minor league player of the year in 2008, when he hit a combined 29 HR with 31 stolen bases at Class A High Desert and Double-A West Tenn. He was rising up the charts so much that prestigious Baseball America ranked him as the #57 prospect before the start of the 2009 season. It felt like it was only a matter of time before he would be in the Emerald City dropping bombs on our A.L. West rivals. But you know what, I’ll stop there with the stats. Yes, Greg Halman was a baseball player and stats often describe and define a player… but Halman was much more than a Mariner prospect. For Dutch baseball, he was an icon. His love for the game was the most evident I have seen in a ballplayer since Ken Griffey Jr. was growing into a man here in Seattle. Halman loved to smile. He loved to hustle. He loved to play the game of baseball at 110%. For many of you who know me, the game of baseball has meant a lot to my life. Some days I’ll even go as far to say baseball saved my life. I never got the chance to play baseball past my early teenage years but that doesn’t mean my childhood dream had to die. Vicariously, through players like Greg Halman who savored every at-bat, every catch, every teammate’s accolade, I could still re-live it. Halman with his first MLB HR - June 15, 2011 vs Angels at Safeco Field I never got the chance to meet Halman but I work with people that did and every single one of them have something nice to say. You don’t find that “real” genuine emotion towards a player too often nowadays. And it’s not because he was a professional athlete that he garnered this praise. They saw the hustle. They saw passion. They saw a little piece of themselves playing whiffleball in the backyard in Greg Halman. That smile… man, that was infectious. Halman showed us why we love baseball. I’m really bumming about this. It put a lump in my throat yesterday and I haven’t been able to shake it. My thoughts have been with everybody involved in this unbelievable tragedy of events. The Seattle Mariners organization is reeling. Back-to-back Novembers with tragic losses. We as fans are hurting. We love this team. We love these players. We love to spend our money to watch the world’s best athletes entertain us with a game we love. Greg Halman gave us that. He gave us hope for a better tomorrow, a better team next season, better days in the future. He gave us his hustle and despite playing less than 100 career games with the M’s, he made his mark. I remember when Greg was called-up and one of his first quotes was “all I want to do is bang”. I loved it! I appreciated his moxie, his confidence, his passion. Greg Halman was a 24-year-old knocking at the door of potential stardom. The Mariners will honor him accordingly during the 2012 season with “GH” on their jerseys. Halman spent a good portion of the last month of his life doing what he loved; being an ambassador to the game. He was on a European tour with other major league players and when they traveled to The Netherlands, he was treated like a rockstar. Reports say he was sought out for autographs and photos at baseball clinics in the same capacity as fellow traveler Prince Fielder. Greg Halman, I will miss your passion. Thank you for everything you did for the game of baseball. Your legacy will live on forever and someday soon other Europeans will be giving you kudos for them reaching the bigs. You’re gone but never to be forgotten. Your life in baseball was such joy… R.I.P. to you, my unknown brother.Q: WPF TreeView does not apply DataTemplate accordingly I have a business object project, which contains composite structure: public class Tree { public IProductComponent TreeRoot { get; set; } } public interface ITreeComponent { public string Name { get; set; } } public class ContainerComponent : ITreeComponent { public BindingList<ITreeComponent> Children { get; set; } } public class LeafComponent : ITreeComponent { } I need to bind this structure to a TreeView in my WPF project. The tree view first: <TreeView x:Name="treeView" Grid.ColumnSpan="2"> <TreeView.Resources> <HierarchicalDataTemplate ItemsSource="{Binding Children}" DataType="{x:Type businessObjects:ContainerComponent}"> <Label Content="{Binding Name}"/> </HierarchicalDataTemplate> <DataTemplate DataType="{x:Type businessObjects:LeafComponent}"> <Label Content="{Binding Name}"/> </DataTemplate> </TreeView.Resources> </TreeView> And the code for binding: bTreeView = new Binding(); bTreeView.Source = MyTree; bTreeView.Path = new PropertyPath("TreeRoot.Children"); treeView.SetBinding(TreeView.ItemsSourceProperty, bTreeView); The problem is that the TReeView does not actually use those templates (it displays only the top level of hierarchy and calls.ToString() to display those items. Please tell me where have I gone wrong. Otherwise, if I set the it is working, but I cannot define two templates there. Thanks. A: My bad - the Main assembly was loading the dll with entities two times instead of one. That caused it to go crazy - as soon as I fixed it and the assembly loaded once the problems went away. Troy Costa Troy Costa (born 1975)is an Indian fashion designer based in Mumbai who owns the Troy Costa menswear label. Known as the man who suits up India's rich and powerful, Troy launched his bespoke menswear fashion label 'Troy Costa Designs' in 2008 after the runaway success of his shows at the 'Dubai Fashion Week' and the 'Lakme Fashion Week'.
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erafts Two life rings with luminous buoys and smoke signals Four line throwing rockets. B.A kit for fire fighting Portable fire extinguishers in accordance with classification society requirements Sixteen type-tested life jackets One set of signal rockets and distress flares Two life rings with attached lines. One 5.6m tender with diesel 2016 One 3.4m Novourania tender with 15HP outboard熱々のダイドーブレンド缶コーヒーが入ったドラム缶を日産キャラバンで差し入れ ダイドードリンコは1月20日、日産自動車とのコラボレーション企画として「ドラム缶コーヒー」を建設現場に差し入れする企画を発表。差し入れ先の応募受付を開始した。 ドラム缶コーヒーは、「ダイドーブレンド デミタスブラック」、「ダイドーブレンド デミタス微糖」が入ったドラム缶。プロジェクト専用に開発した保温機能を持ち、自動販売機のホットドリンクと同様に最適な加温温度を保つ。とくに今回は、気温の低い屋外の作業現場を考慮し、少し熱めの 58度以上の設定を行なっている。 応募受付は2月21日17時まで。プロジェクト特設サイトのフォームから応募すれば、抽選で関東1 都6県の建設現場（最大10現場）に差し入れ。届ける際には、差し入れ人員として「助太刀」アプリで募集した職人により、専用車両となる日産「キャラバン」で届けて回る。 また、抽選から外れた人を対象に、抽選で100名（100現場）にダイドーブレンド デミタスシリーズの缶コーヒー1ケース（30本入り）、合計3000本を郵送で「差し入れ」としてプレゼントする。Periodate-sensitive immunological cross-reactivity between keyhole limpet haemocyanin (KLH) and serodiagnostic Schistosoma mansoni egg antigens. Both CEF6, a cation-exchange fraction of soluble Schistosoma mansoni egg antigens (SEA), composed of the 2 antigens, alpha-1 and omega-1, and haemocyanin from the keyhole limpet, Megathura crenulata, have shown potential for immunodiagnosis of human schistosomiasis. Possible cross-reactivity between antigens in SEA and keyhole limpet haemocyanin (KLH) was explored by Western immunoblotting and enzyme-linked immunosorbent assay (ELISA) using sera from rabbits immunized with KLH, SEA, CEF6, alpha-1, omega-1, or egg antigen k5. Both immunoassays revealed a high degree of serological cross-reactivity between the schistosome egg antigens and KLH, much of it due to sodium periodate-sensitive epitopes. Cross-reactivity with schistosome antigens with proven diagnostic efficacy may thus, in part, explain the usefulness of KLH for the diagnosis of human schistosomiasis mansoni.March 31, 2017Joe Feddersen included in "Without a Theme" at the Pequot Museum Joe Feddersen is one of the artists included in "Without a Theme", an exhibit at the Pequot Museum, Mashantucket, CT, on view March 31 - November 2, 2017. Without a Theme is an immersive display showcasing approximately 20 vibrant, large-format installations from seven premier North American artists. The exhibition will be housed in the Mashantucket Gallery until Nov. 2 and is included in general museum admission. “Without a Theme is an important concept behind this incredible contemporary collection,” said Tahnee Ahtoneharjo-Growingthunder, curator, Pequot Museum. “We strategically immerse visitors in large, vibrant installations – letting the purpose, message and emotion of each piece move the individual. This is in mindful contrast to popular Native exhibits in which emphasis is placed on the artist’s heritage, or on visual themes that don’t necessarily convey modern Native life. Our focus on color and composition - rather than theme - allows the artists’ connections to their community and their purpose to speak for itself.” Exhibition pieces are composed of acrylic, mixed media, glass, sterling, and organic materials. Featured artists include: Jeff Kahm, Saskatchewan, Canada//---------------------------------------------------------------------- // Class: CGUIPosition // Authors: LiXizhi // Date: 2005.8.1 // desc: moved to new class file 2014.8.9 //----------------------------------------------------------------------- #include "ParaEngine.h" #include "GUIPosition.h" #include "IScene.h" #include "BaseObject.h" using namespace ParaEngine; ParaEngine::CGUIPosition::CGUIPosition() :m_fDepth(0), m_nPositionType(relative_to_parent), m_n3DObjectID(0) { memset(&rect, 0, sizeof(RECT)); memset(&Relative, 0, sizeof(_relativity)); } ParaEngine::CGUIPosition::CGUIPosition(const RECT& rect_) :rect(rect_), m_fDepth(0), m_nPositionType(relative_to_parent), m_n3DObjectID(0) { memset(&Relative, 0, sizeof(_relativity)); } ParaEngine::CGUIPosition::CGUIPosition(int x, int y, int width, int height) : m_nPositionType(relative_to_parent) { rect.left = x; rect.top = y; rect.right = x + width; rect.bottom = y + height; m_fDepth = 0; memset(&Relative, 0, sizeof(_relativity)); } void ParaEngine::CGUIPosition::SetDepth(float Depth) { if (m_nPositionType == relative_to_3Dobject) { Relative.To3D.fOffSet = Depth; } else{ m_fDepth = Depth; } } void ParaEngine::CGUIPosition::Update3DDepth(float Depth) { m_fDepth = Depth; } int ParaEngine::CGUIPosition::GetWidth() const { if (IsNormalWidthHeight()) return rect.right - rect.left; else return rect.right; } int ParaEngine::CGUIPosition::GetHeight() const { if (IsNormalWidthHeight()) return rect.bottom - rect.top; else return rect.bottom; } float ParaEngine::CGUIPosition::GetDepth() const { if (m_nPositionType == relative_to_3Dobject) { return Relative.To3D.fOffSet + m_fDepth; } else return m_fDepth; } void ParaEngine::CGUIPosition::SetLeft(int X) { rect.left = X; } void ParaEngine::CGUIPosition::SetTop(int Y) { rect.top = Y; } void ParaEngine::CGUIPosition::SetXY(int X, int Y) { int width = rect.right - rect.left; int height = rect.bottom - rect.top; rect.left = X; rect.top = Y; rect.bottom = rect.top + height; rect.right = rect.left + width; } void ParaEngine::CGUIPosition::SetSize(int width, int height) { SetWidth(width); SetHeight(height); } int CGUIPosition::SetAlignment(const char* alignment) { /* destination position of the object in the screen coordinates */ m_nPositionType = CGUIPosition::relative_to_parent; Relative.To2D.alignType = CGUIP
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Syscall(SYS_GETDENTS64, uintptr(fd), uintptr(_p0), uintptr(len(buf))) n = int(r0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Getpgid(pid int) (pgid int, err error) { r0, _, e1 := RawSyscall(SYS_GETPGID, uintptr(pid), 0, 0) pgid = int(r0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Getpid() (pid int) { r0, _, _ := RawSyscall(SYS_GETPID, 0, 0, 0) pid = int(r0) return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Getppid() (ppid int) { r0, _, _ := RawSyscall(SYS_GETPPID, 0, 0, 0) ppid = int(r0) return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Getpriority(which int, who int) (prio int, err error) { r0, _, e1 := Syscall(SYS_GETPRIORITY, uintptr(which), uintptr(who), 0) prio = int(r0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Getrusage(who int, rusage *Rusage) (err error) { _, _, e1 := RawSyscall(SYS_GETRUSAGE, uintptr(who), uintptr(unsafe.Pointer(rusage)), 0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Gettid() (tid int) { r0, _, _ := RawSyscall(SYS_GETTID, 0, 0, 0) tid = int(r0) return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Getxattr(path string, attr string, dest []byte) (sz int, err error) { var _p0 *byte _p0, err = BytePtrFromString(path) if err!= nil { return } var _p1 *byte _p1, err = BytePtrFromString(attr) if err!= nil { return } var _p2 unsafe.Pointer if len(dest) > 0 { _p2 = unsafe.Pointer(&dest[0]) } else { _p2 = unsafe.Pointer(&_zero) } r0, _, e1 := Syscall6(SYS_GETXATTR, uintptr(unsafe.Pointer(_p0)), uintptr(unsafe.Pointer(_p1)), uintptr(_p2), uintptr(len(dest)), 0, 0) use(unsafe.Pointer(_p0)) use(unsafe.Pointer(_p1)) sz = int(r0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func InotifyAddWatch(fd int, pathname string, mask uint32) (watchdesc int, err error) { var _p0 *byte _p0, err = BytePtrFromString(pathname) if err!= nil { return } r0, _, e1 := Syscall(SYS_INOTIFY_ADD_WATCH, uintptr(fd), uintptr(unsafe.Pointer(_p0)), uintptr(mask)) use(unsafe.Pointer(_p0)) watchdesc = int(r0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func InotifyInit1(flags int) (fd int, err error) { r0, _, e1 := RawSyscall(SYS_INOTIFY_INIT1, uintptr(flags), 0, 0) fd = int(r0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func InotifyRmWatch(fd int, watchdesc uint32) (success int, err error) { r0, _, e1 := RawSyscall(SYS_INOTIFY_RM_WATCH, uintptr(fd), uintptr(watchdesc), 0) success = int(r0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Kill(pid int, sig syscall.Signal) (err error) { _, _, e1 := RawSyscall(SYS_KILL, uintptr(pid), uintptr(sig), 0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Klogctl(typ int, buf []byte) (n int, err error) { var _p0 unsafe.Pointer if len(buf) > 0 { _p0 = unsafe.Pointer(&buf[0]) } else { _p0 = unsafe.Pointer(&_zero) } r0, _, e1 := Syscall(SYS_SYSLOG, uintptr(typ), uintptr(_p0), uintptr(len(buf))) n = int(r0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Listxattr(path string, dest []byte) (sz int, err error) { var _p0 *byte _p0, err = BytePtrFromString(path) if err!= nil { return } var _p1 unsafe.Pointer if len(dest) > 0 { _p1 = unsafe.Pointer(&dest[0]) } else { _p1 = unsafe.Pointer(&_zero) } r0, _, e1 := Syscall(SYS_LISTXATTR, uintptr(unsafe.Pointer(_p0)), uintptr(_p1), uintptr(len(dest))) use(unsafe.Pointer(_p0)) sz = int(r0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Mkdirat(dirfd int, path string, mode uint32) (err error) { var _p0 *byte _p0, err = BytePtrFromString(path) if err!= nil { return } _, _, e1 := Syscall(SYS_MKDIRAT, uintptr(dirfd), uintptr(unsafe.Pointer(_p0)), uintptr(mode)) use(unsafe.Pointer(_p0)) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Mknodat(dirfd int, path string, mode uint32, dev int) (err error) { var _p0 *byte _p0, err = BytePtrFromString(path) if err!= nil { return } _, _, e1 := Syscall6(SYS_MKNODAT, uintptr(dirfd), uintptr(unsafe.Pointer(_p0)), uintptr(mode), uintptr(dev), 0, 0) use(unsafe.Pointer(_p0)) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE IS GENERATED BY THE COMMAND AT THE TOP; DO NOT EDIT func Nanosleep(time *Timespec, leftover *Timespec) (err error) { _, _, e1 := Syscall(SYS_NANOSLEEP, uintptr(unsafe.Pointer(time)), uintptr(unsafe.Pointer(leftover)), 0) if e1!= 0 { err = errnoErr(e1) } return } // THIS FILE
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"Return the money." "Why should I let you have it?" "It's all she's got left." "Who gives a shit!" "She's an investor." "I've got the papers!" "Return those papers to her." "What's that?" "Yamashita" "No need to get involved." "Return the power of attorney." "Are you crazy?" "Return it to her." "No way." "What's it to be?" "Yes, or no?" "What's with you?" "She's only worth fucking!" "You bastard!" "You stay out of it!" "Look carefully, officer." "It's me being violent." "Okay, stop it." "That's enough." "Everyone, stop it!" "That's enough!" "Where's my money, bitch?" "Stop it!" "It's all her doing!" "Where did you hide my money?" "Tell me the truth." "She threw herself at me, too." "You're both fucking crazy!" "Don't stop me." "Damn you!" "You bitch!" "Yamashita!" "Stop it!" "Stop it, I said!" "Keiko's pregnant!" "You're all fixed." "Pregnant with my kid?" "No way!" "It's not yours!" "Then, is it his?" "Yes, it's mine!" "Fuck you!" "Stop it now!" "What have I done!" "I'm sorry!" "You mongrel!" "Lady!" "That's enough!" "Get out of my way!" "It's my baby." "Police Station" "How did it go?" "The power of attorney has no signature." "The money belongs to your mother after all." "And Mr. Yamashita?" "No charges against Takada." "But as for Yamashita, there'll be a parole violation hearing." "Too see if the parole will be cancelled." "He'll have to wait four or five days." "I'll be in touch." "I'm sorry." "Does your head still hurt?" "No, I'm okay." "It doesn't hurt anymore." "I got you into this." "I did it on my own." "We decided to have a party tonight." "All of us?" "To shed the bad luck and celebrate your lady's pregnancy." "Takuro Yamashita and Keiko Hattori are having a baby." "Celebrate my pregnancy?" "Sorry." "Everyone thinks it's yours." "It must bother you." "They'd decided anyway." "I just confirmed it." "I'll have an abortion." "Don't." "Have the baby." "The reverend can sit in the middle." "Look." "Come on, Masaki!" "Where are you going, Yuji?" "Where are you going?" "C'mon, applaud!" "Mr. Yamashita, dance with me." "Come on." "First a brat..." "Next a murderer..." "What a pervert." "There were no letters." "Jealousy made you hallucinate." "Finally I've become like you." "I'll raise a kid by some unknown father." "Your mother laid her eggs near the equator." "Anonymous sperm fertilized them to life." "Nobody knows the sperm came from which fish." "Nobody knows your father." "But you're still a fantastic eel." "Sacrificing themselves, they escort the babies back to Japan." "Those who are born should be cared for, right?" "Time to say good-bye." "Farewell." "My statement should carry some clout." "You'll soon be free again." "Thank you." "How long do you think?" "About a year, I reckon." "Can we stop on the way?" "Sure." "We'll wait here." "Can we borrow the flagpole?" "Yes." "Thank you." "Take good care of yourself." "Can I wait for you?" "Wait until you come back?" "Take good care of the baby." "We'll both be waiting for you." "Did you know that eels travel far?" "What's that?" "They travel as far as the equator then return to the mud here." "They live in the places they like." "You think they'll come?" "Who?" "The flying saucers." "If you put your heart into it, I'm sure they will."3*s - 1)**2/4 Let o(t) be the third derivative of 1/84*t**6 + 12*t**2 + 0 + 4/105*t**5 + 2/7*t**3 - 17/84*t**4 - 2/735*t**7 + 0*t. Solve o(p) = 0. -2, 1/2, 1, 3 Let j(b) be the third derivative of b**6/40 - 3*b**5/10 + 16*b**3 - 70*b**2. Determine s, given that j(s) = 0. -2, 4 Let y = 493 - 489. Let s(q) be the first derivative of -1 - 13*q**2 - 17/2*q**y + 4*q + 8/5*q**5 + 16*q**3. Factor s(b). 2*(b - 2)*(b - 1)**2*(4*b - 1) Suppose -5*y - 2 = -4*b, 4*y - 5*b - 17 = -8*b. What is l in 40 - 22*l + 137*l**y - 14*l - 141*l**2 = 0? -10, 1 Let f(i) = 50*i**4 + 220*i**3 + 35*i**2 + 35. Let w = -56 + 21. Let n(r) = 3*r**4 + 13*r**3 + 2*r**2 + 2. Let q(h) = w*n(h) + 2*f(h). Factor q(m). -5*m**3*(m + 3) Let q = 979 - 8801/9. Let z(h) be the first derivative of -10/3*h**2 + 5 + 40/3*h - q*h**3 + 5/12*h**4. Determine x so that z(x) = 0. -2, 2 Let y(w) be the second derivative of -w**7/42 + w**6/30 + w**5/4 - w**4/12 - 4*w**3/3 - 2*w**2 - 21*w. Suppose y(d) = 0. What is d? -1, 2 Let r(i) = -2*i**3 + 5*i**2 + 12. Let l be r(3). Factor 0*x + 2*x**4 + 0*x**2 - 4/5*x**l + 0. 2*x**3*(5*x - 2)/5 Suppose -8154*m**3 - 5*m**5 + 8162*m**3 + 6*m**4 + 3*m**5 = 0. What is m? -1, 0, 4 Let p(c) be the third derivative of -c**5/140 - 33*c**4/56 + 17*c**3/7 + 48*c**2. Determine s so that p(s) = 0. -34, 1 Factor 14/3*i + 2/3 + 13/6*i**2. (i + 2)*(13*i + 2)/6 Factor -1/7*v**3 + 1/7*v**5 - 3/7*v**2 + 0*v + 3/7*v**4 + 0. v**2*(v - 1)*(v + 1)*(v + 3)/7 Solve 7*a**3 - 65*a - 4*a**3 + 29*a - 27*a**2 + 60 + 0*a**3 = 0 for a. -2, 1, 10 Let q(z) be the third derivative of 1/1680*z**8 + 1/30*z**4 + 0 + 0*z + 1/75*z**5 - 1/525*z**7 + z**2 - 1/200*z**6 + 0*z**3. Let q(w) = 0. What is w? -1, 0, 2 Let d = -74 + 77. Factor 3*j - 5*j - d*j**3 + 7*j**3 - 2*j**3. 2*j*(j - 1)*(j + 1) Let q(m) be the first derivative of -52/9*m**2 + 16/9*m + 188/27*m**3 - 35/18*m**4 - 27. Let q(k) = 0. Calculate k. 2/7, 2/5, 2 Suppose 12 = c + 2*o, -3*o - 6 - 6 = 0. Suppose -u - 2*u = -15, 0 = 5*r + u - c. Solve 2*t**r + 46*t - 2*t**5 - 46*t = 0. -1, 0, 1 What is h in -5*h**5 + 0*h
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,g\}.\end{gathered}$$ Moreover, the bracket of two closed forms is again closed. In fact, the properties above characterize the Lie algebroid structure on the cotangent bundle that comes from a Poisson bracket on the base manifold (see [@Hue90; @Du05]). More precisely, given a Lie algebroid $(T^* M, [\![ \cdot,\cdot ]\!],\rho )$ on the cotangent bundle $T^* M$, there exists a Poisson bracket $\{ \cdot,\cdot\}$ on $M$ such that $\rho =P$ if and only if the following conditions are satisfied: (a) \[a\] $\rho$ is skew-symmetric, i.e. $\beta (\rho (\alpha ))=-\alpha (\rho (\beta ))$, for all $\alpha,\beta\in\Omega^1 (M)$. (b) \[b\] If $\alpha,\beta\in\Omega^1 (M)$ are closed, then $[\![ \alpha,\beta]\!]$ is also closed. The aim of the present work is to put the study of cotangent Lie algebroids of Poisson manifolds in an algebraic framework. In the first part (Section \[LiePoisson\]), we study and characterize a class of Lie algebroids with properties similar to , , which we call Lie algebroids of Poisson type. To this end, we will work in a slightly more general context than that of vector bundles over manifolds, using the notion of Lie–Rinehart algebra (see [@Hue90; @Hue98]), also called a Lie pseudoalgebra (see [@KM90; @Mc95; @Mc05; @Ri63] and, particularly, [@KM02] for many interesting remarks on the evolution of these notions and as a general reference), although we will continue using the denomination “Lie algebroid” for them (as they are the algebraic version of the geometric Lie algebroids). The dictionary in Example \[ec\] can be used at any time to obtain the corresponding expressions for geometric Lie algebroids. We give several examples illustrating the different situations that can appear. In the second part (Sections \[Transitive\] and \[Poisson\]), we deepen in the relationship between transitive algebroids and Poisson structures for a certain class of spaces, those of the form, where $\mathcal{A}$ is a commutative algebra and $V$ an $\mathcal{A}$-module. We describe parametrizations of the transitive Lie algebroids on $\mathrm{Der}(\mathcal{A})\oplus V$ following the techniques exposed in [@Yu01; @Yu04], which are based on the use of a connection on a Lie algebroid. For completeness, we include a subsection in the preliminaries devoted to the topic of connections in an algebraic setting. Once the parametrization is given, we apply it to prove that a transitive algebroid endowed with a connection is isomorphic to one of the form $\mathrm{Der}(\mathcal{A})\oplus V$. Finally, we obtain new classes of Poisson algebras on $\mathcal{A}\oplus V$ starting from Poisson algebras on $\mathcal{A}$. Preliminaries {#Preliminaries} ============= Throughout the document, unless otherwise explicitly stated, $\mathcal{A}$ denotes an associative, commutative algebra with identity element $1_{\mathcal{A}}$, over a commutative ring $\mathcal{R}$ with identity element $1_{\mathcal{R}}$. Derivations and connections in commutative algebras {#subsec21} --------------------------------------------------- In subsequent sections, we will need to introduce connections on an algebroid. In our algebraic setting, the most appropriate notion of connection is Koszul’s one, which is given in terms of derivations. A derivation of the algebra $\mathcal{A}$ over $\mathcal{R}$ is a map $X \in \mathrm{Hom}_{\mathcal{R}}(\mathcal{A},\mathcal{A})$ satisfying the Leibniz rule $$\begin{gathered} X (f\cdot g)=X(f)\cdot g+f\cdot X(g).\end{gathered}$$ The set of derivations of $\mathcal{A}$ over $\mathcal{R}$ is denoted $\mathrm{Der}_{\mathcal{R}}(\mathcal{A})$ or simply $\mathrm{Der}(\mathcal{A})$ when there is no risk of confusion about the ring $\mathcal{R}$. The definition just given can be extended to the case of derivations of $\mathcal{A}$ over $\mathcal{R}$ with values in an $\mathcal{A}$-module $M$. These are Abelian groups morphisms $X:\mathcal{A}\rightarrow M$ satisfying the Leibniz rule above, and form an $\mathcal{A}$-module denoted $\mathrm{Der}_{\mathcal{R}}(\mathcal{A},M)$ or simply $\mathrm{Der}(\mathcal{A},M)$. The set $\mathrm{Der}(\mathcal{A})$ has an $\mathcal{R}$-Lie algebra structure when endowed with the commutator of endomorphisms, given by $[X,Y ]=X \circ Y -Y \circ X$. Note also that, if $\mathcal{A}$ as an $\mathcal{R}$-module is faithful, then for every $X\in \mathrm{Der}(\mathcal{A})$ we have $X (1_{\mathcal{A}})=0$ and indeed $X(r)=0$ for every $r\in \mathcal{R}$ viewed as a subalgebra of $\mathcal{A}$. Let $M$ be an unitary $\mathcal{A}$-module. A derivation law, or Koszul connection, on $M$ is an $\mathcal{A}$-linear mapping $\nabla :\mathrm{Der}(\mathcal{A})\rightarrow \mathrm{Hom}_{\mathcal{R}}(M,M)$ (the image of $X\in \mathrm{Der}(\mathcal{A})$ denoted $\nabla_X$) such that $$\begin{gathered} \nabla_X (f\cdot m)=X(f)\cdot m+f\cdot \nabla_X(m).\end{gathered}$$ Not every $\mathcal{A}$-module $M$ admits a connection in this sense, but it is easy to see that any free $\mathcal{A}$-module does. Of course, arbitrary $\mathcal{A}$-modules do not need to be free. So, in order to obtain a big enough class of modules for which we can guarantee the existence of a Koszul connection, we will make a brief digression on modules of differentials and Connes connections (see [@Co85]). Let $\Omega^1 (\mathcal{A})$ be the $\mathcal{A}$-module defined by the kernel of the multiplication $\mathcal{A} \otimes_{\mathcal{R}} \mathcal{A}\rightarrow \mathcal{A}$. Define the map $\mathrm{d}:\mathcal{A}\rightarrow \Omega^1 (\mathcal{A})$ by $\mathrm{d}a=1\otimes a -a\otimes 1$, which is a derivation of $\mathcal{A}$ over $\mathcal{R}$ with values into $\Omega^1 (\mathcal{A})$. It is clear from the definition that $\Omega^1 (\mathcal{A})=\mathrm{Span}_{\mathcal{A}}\{ \mathrm{d}f:f\in \mathcal{A}\}$: Since the elements of $\Omega^1 (\mathcal{A})$ lie in the kernel of the multiplication map, if $\sum a_j \otimes b_j \in \Omega^1 (\mathcal{A})$, then $\sum a_jb_j=0$ and therefore $$\begin{gathered} \sum a_j \otimes b_j =\sum (a_j \otimes b_j -a_jb_j \otimes 1)=\sum a_j\mathrm{d}b_j.\end{gathered}$$ In fact, $\Omega^1 (\mathcal{A})$ is the submodule of $C^1 (\mathrm{Der}(\mathcal{A}),\mathcal{A})$ (the $1$-component of the differential algebra $C(\mathrm{Der}(\mathcal{A}),\mathcal{A})$ of Chevalley–Eilenberg cochains of the Lie algebra $\mathrm{Der}(\mathcal{A})$ with values in the $\mathrm{Der}(\mathcal{A})$-module $\mathcal{A}$) generated by the elements $\mathrm{d}f$, $f\in\mathcal{A}$ (see [@DM94]). Note, in particular, that this implies $\Omega^1 (\mathcal{A})\subset \mathrm{Der}^* (\mathcal{A})$. Let $M$ be an $\mathcal{A}$-module. A Connes connection on $M$ is an $\mathcal{A}$-linear map $\delta :M\rightarrow \Omega^1 (\mathcal{A})\otimes_{\mathcal{A}}M$ such that, for all $f\in\mathcal{A}$, $m\in M$, $$\begin{gathered} \delta (fm)=f\delta (m)+\mathrm{d}f \otimes_{\mathcal{A}}m.\end{gathered}$$ Connes’ definition of a connection (see [@Co85]) actually does not require that $\mathcal{A}$ be a commutative algebra. The definition goes back to a work by N. Katz [@Ka70]. Starting from a Connes connection, we can obtain a Koszul one. If $X\in \mathrm{Der}(\mathcal{A})$, then we define a right $\mathcal{A}$-linear pairing $\varphi: \mathrm
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"Real-estate agents often keep erratic hours, so nobody would question if she wasn't in the office at any given time. She could probably meet clients day or night, accommodate their schedules easily." "And since she was the dominant," Hollis said, "she could probably take on as many clients as her energy allowed. No need to take a day or week off now and again to allow those ugly bruises and burns to heal. Or whatever else there might be. She'd be the one dealing out the punishment. Jesus." Hearing the distaste in the other woman's voice, Mallory grimaced in agreement. "A very twisted way to find pleasure, if you ask me." Ginny joined them in time to get the gist of the conversation, saying, "The things people get up to behind closed doors. We've found Rose Helton." "Alive and well, I gather?" Mallory said. "Definitely alive. I'd say pissed rather than well. When I told her that her husband was sleeping it off in a cell after having waved his gun around at the chief and two federal agents, she said she hoped the judge would throw away the key." "Where is she?" Hollis asked. "In Charleston, with a college friend." "She went to college?" Mallory asked in surprise. "And still married Tim Helton?" Pronouncing the words carefully, Ginny said, "She said it had been a cosmic karmic mistake. And that she'd already filed for divorce and wasn't coming back here. And, oh, by the way, in case we hadn't found it, there was also a still in an old shed in the back pasture." "We found it," Hollis murmured. "Everybody said they were so happy." Mallory shook her head. "Christ, you really don't know about people." Hollis said, "Well, anyway, we can cross her off the missing list." "One less to worry about," Ginny agreed. "How's the rest of the list coming?" Mallory asked her. "No change. No sign of Cheryl Bayne. Plus, we still have several women missing in the general area, and nothing new on Kate Murphy." Ginny sighed, clearly weary. "It's like she disappeared into thin air. She fits right in with the other victims too." "But not Cheryl Bayne." Hollis said, "I think Isabel's probably right about Cheryl. If the killer got her, it wasn't specifically because she was—is—a reporter, but because she somehow got too close. Or he was afraid she had. And if so, it's only going to get more difficult to even try to predict what he might do next." "Except kill," Mallory offered wryly. It was Hollis's turn to rub the back of her neck. "And there's something else. Isabel's the profiler, but I've got to say, if Kate Murphy is a victim, why haven't we found her? So far, the rule's been that if he kills them, he does it quick and leaves them out in the open where they're easily found. Assuming he has killed again, or that he has Kate Murphy, why would he change his M.O. now?" "Our patrols are checking out every highway rest stop," Ginny said. "Most of them two or three times a day." "Maybe we've spooked him," Mallory suggested. "He could be killing and leaving the bodies in places we aren't keeping under observation." Hollis glanced toward the closed door of the conference room. "Maybe it's time we discussed that possibility." Mallory didn't move. "Rafe had a sort of determined look on his face when he closed the door. I'm not so sure I want to be the one to disturb them." Hollis continued to look at the door intently, focusing, tentatively trying out the spider sense. After a long moment, she said, "Um... let's give them a few more minutes." "You're serious?" Rafe leaned forward and touched her hand, not even reacting now to the spark. Isabel looked down at their hands for a moment, then back at his face. "Entirely serious. For the first time in more than fourteen years, there's silence in my head." "That's what's been wrong all day." "That's it," she said, unsurprised that he had noticed. "The question is: why?" They both looked down at their touching hands, and Rafe said, "Frontier territory, huh?" "Yeah. Scary, isn't it?" "Today, looking at the wrong end of a gun being waved around by a paranoid drunk, was scary. This? This is just a very interesting turn my life has taken." "You're a very unusual man," she said. "Which is probably a good thing," he said, "considering that you're a very unusual woman." There was a part of Isabel that wanted to shy away, to pretend he hadn't said that or that she hadn't understood what he meant. But Isabel didn't let herself shy away, or draw away, or back away. Whatever this was, it was something she had to deal with. "Rafe, do you realize what this could mean?" "Static electricity is more important than I thought it was?" "Electromagnetic energy. And, no, not that." "Then I don't have a clue what this could mean. Or even what this is." "Hollis and I have a theory." "Which is?" "The theory is, my abilities are still with me, it's just that now there's something standing between me and the great wide world out there." "You're not saying—" "We think it might be you." "You are saying." He frowned at her. "Isabel, how could it be me? I'm not psychic. I wouldn't even know how to _be_ psychic." "We think that might be the problem." Rafe waited, brows raised. "When a latent first becomes a functional psychic, there's an adjustment period. The psychic isn't in control of his or her abilities from the get-go. I mean—look at Hollis. She's been a medium for months and still can't open and close that door at will. It takes concentration, and focus, and practice. A lot of practice." "I'm not psychic." He said it with more wariness than uncertainty. "Your grandmother was." "So?" "So sometimes it runs in families. Your chances of being a latent psychic are much higher than average." "I still don't—" "Look. There was a connection between us from the beginning. Call it an attraction, a sense of understanding, simpatico, whatever. It was there. We both felt it." "I felt that, yes." "We feel it now," she said, admitting it. Rafe nodded immediately. "We feel it now." "And there's the sparking thing. I told you that was something new for me." "Electromagnetic energy fields. Basic science." "Yeah, but the way those fields were reacting to each other and the strength of that reaction was something different. Something that might have affected my abilities." "Okay. But—" "Rafe. There was this connection, this... conduit between you and me. Maybe the energy opened it, or maybe... Maybe the energy opened it. And then when I told you about what had happened to me, you reached out. Through the conduit. You wanted the pain to go away. And it did." Rafe spoke very carefully. "How could I have done anything to... put your abilities in a box?" "Actually, that's a very good description," she noted. "Isabel." "Okay. One of the things we've discovered is that the subconscious is often more in control of our abilities than the conscious mind is, especially in a newly functional psychic. One theory is that it's because these are very old abilities—not new ones. They were born out of instinct, when primitive humans needed every possible edge just to survive." "Makes sense," Rafe said. "Yes, it does. And if you subscribe to that theory, it also makes sense that our subconscious minds—the deeply buried, primitive id—would not only be able to master psychic abilities but would do so immediately and skillfully. To that part of us, being psychic would be perfectly natural." "My id put your abilities in a box?" Thoughtfully, Isabel said, "Has it occurred to you that we have very strange conversations?" "Constantly. Answer my question." "Yes. More or less. Rafe, your nature is very protective, and even though you like and respect strong women and are perfectly able to work alongside us on equal terms, deep down inside, you will always want to protect anyone you... care about. That is your instinctive response." "Anyone I care about." "Yes. And, obviously, the more you care, the more...
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my hometown; Cheri is my lovely wife; Photography and pool are my most active hobbies; Crohn's Disease is my ailment; Virginia Tech and The George Washington University are the schools I graduated from; Cookies & Cream is my favorite ice cream flavor. Also, fallenposters is the alias I use on most websites. It was the first username I came up with when joining instant messenger in college. The first thing I saw was the posters that had fallen from my dorm room wall, and the rest is history.International Patient Videos Mrs. Anderson, DubaiRhinoplasty India Rhinoplasty Surgery performed on Dubai National in Mumbai, in India Hello. I am Mr. Anderson. Recently my wife got her Rhinoplasty Surgery in India at Mumbai. She was not happy about her nose and would put a lot of make up to camouflage the flaws. But we were looking for a more permanent solution to it. So she decided to get a Rhinoplasty Surgery. We chose India because we had heard about the flourishing medical tourism in India. We surfed the internet and came across the website of Forerunners Healthcare Group. We called them up and they arranged everything. They also helped us out with the visa procedure. With the help of Forerunners Healthcare Group my wife got her Rhinoplasty Surgery in India at one of the best hospitals in Mumbai. Content on this page requires a newer version of Adobe Flash Player. At the hospital, we noticed that many patients were from foreign countries. The doctors, surgeons and the nurses were very kind and the communication was very easy as all of them spoke good English. My wife’s Rhinoplasty Surgery in India was performed by one of the best cosmetic surgeons in the country. The results she got after the surgery has exceeded our expectations. After getting Rhinoplasty Surgery in India, my wife’s nose looks perfect and she doesn’t need to put layers of make up anymore. I think we made the right decision by getting my wife’s Rhinoplasty Surgery in India and would suggest the same to all those who are looking for medical treatment overseas.It’s been a crazy month for the guys at Xenophile media. It started off back in March at the 10th Annual SXSW Interactive Awards when Occular Effect (The Fallen Alternate Reality Game) won the award in the Experimental category. But it was not about to stop there. The nominations were just beginning to roll in. Fallen was nominated for a Banff World Television Award and Regenesis was nominated for both an Interactive Emmy (pdf) and a CNMA Award. The CNMA and Banff World Television awards will be announced in the next few months, but last night the Interactive Emmywent to(pdf)… Xenophile Media for Regenesis Extended Reality Game! Clearly, they’re going to need to build themselves a bigger trophy case. But the real question is, how are they ever going to get any work done with all this celebrating? We want more!New medical device perspectives from integrated optics and fibre optics. Integrated optics technology has a great potential for medical device applications. This article explains the technology and how it can be used with particular reference to in vitro diagnostics and endoscopy. IN THE TENTH COURT OF APPEALS No. 10-11-00424-CR THOMAS HENRY SINCLAIR, Appellant v. THE STATE OF TEXAS, Appellee From the 13th District Court Navarro County, Texas Trial Court No. 33805-CR MEMORANDUM OPINION The jury convicted Thomas Henry Sinclair of the offense of assault and assessed his punishment at one year confinement in the county jail and a $4,000 fine. On April 24, 2014, this Court issued an opinion affirming Sinclair’s conviction. Sinclair filed a petition for discretionary review with the Court of Criminal Appeals. The Court of Criminal Appeals vacated the April 24 judgment of this Court and remanded the cause. We affirm. Background Facts Sinclair operates Wispers nightclub, and Fernando Ramirez was a patron at the nightclub. Ramirez paid for private dances at the nightclub, and he went with a dancer to the VIP room. The dancer testified that Ramirez requested her to perform sex acts, which she refused, and she left the VIP room. Ramirez went to Sinclair requesting a refund, but Sinclair refused to give the refund. Sinclair testified that Ramirez took a swing at him and threw things at him. Sinclair struck Ramirez with a sjambok, a type of whip. Jeff Ballew, the DJ at Wispers, then came and yanked Ramirez by the collar backwards to the ground. Some patrons of the nightclub dragged Ramirez out of the nightclub and into the parking lot by his feet. Ramirez was taken to a local hospital where he was pronounced dead. The medical examiner testified that Ramirez died from blunt force head injuries. Ramirez had an “abrasive contusion” on the back of his head consistent with his head hitting a hard, rough surface. Extraneous Offense In the third issue on appeal, Sinclair complained that the trial court erred in admitting evidence of an extraneous offense because the State failed to provide reasonable notice of the extraneous offense. Sinclair complains that the trial court erred in admitting the testimony of Jeff Ballew that Sinclair had used the sjambok on another patron of the nightclub on a previous occasion. Ballew stated that Sinclair struck the man with the sjambok and that Ballew intervened and broke up the altercation. Sinclair v. State Page 2 In our April 24 opinion, we found that the trial court did not abuse its discretion in admitting evidence of the extraneous offense. Sinclair argued in his petition for discretionary review that we provided no analysis and cited no authority in overruling the issue. The Court of Criminal Appeals remanded for this Court to reconsider that particular issue. We review a trial court's decision to admit or exclude evidence for an abuse of discretion. McDonald v. State, 179 S.W.3d 571, 576 (Tex. Crim. App. 2005). “Under an abuse of discretion standard, an appellate court should not disturb the trial court's decision if the ruling was within the zone of reasonable disagreement.” Bigon v. State, 252 S.W.3d 360, 367 (Tex. Crim. App. 2008). We will affirm the decision of the trial court if there is any valid ground upon which the decision could have been made. State v. Ross, 32 S.W.3d 853, 856 (Tex. Crim. App. 2000). Rule 404(b) of the Texas Rules of Evidence provides: Evidence of other crimes, wrongs or acts is not admissible to prove the character of a person in order to show action in conformity therewith. It may, however, be admissible for other purposes, such as proof of motive, opportunity, intent, preparation, plan, knowledge, identity, or absence of mistake or accident, provided that upon timely request by the accused in a criminal case, reasonable notice is given in advance of trial of intent to introduce in the State's case-in-chief such evidence other than that arising in the same transaction. Sinclair argues that the State’s notice of the extraneous offense was untimely. Sinclair filed a request for notice of extraneous offenses on November 16, 2009, and the trial court granted the request on January 14, 2010. At a pretrial hearing on September 2, 2011, the State indicated that they did not intend to offer any extraneous offenses or Sinclair v. State Page 3 bad acts at trial. On October 17, 2011, the first day of voir dire, the State filed written notice of intent to introduce evidence of extraneous offenses and acts. The notice stated that the State intended to introduce evidence that Sinclair “has, on occasions other than the charged offense, assaulted people with a whip at the Wispers Cabaret in Navarro County Texas.” Prior to Ballew’s testimony on October 21, 2011, the trial court held a hearing outside the presence of the jury. Sinclair argued that the evidence was untimely and highly prejudicial. The State indicated that Ballew had informed them of the act on the morning of voir dire and that they provided notice at that time. To preserve error regarding the State's failure to provide reasonable notice of its intent to use extraneous offense evidence, the defendant must request a continuance to mitigate the effects of surprise. See Martines v. State, 371 S.W.3d 232, 249 (Tex.App.- Houston [1 Dist.] 2011, no pet.); Martin v. State, 176 S.W.3d 887, 900 (Tex.App.-Fort Worth 2005, no pet.). Sinclair did not request a continuance to allow additional time to investigate the allegations or prepare a defense. Sinclair failed to preserve his complaint for appellate review that the State did not provide reasonable notice of the extraneous offense. See Martines v.
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Giovanna Lacerti (born 1935) is an Italian artist. Lacerti is a Latter-day Saint. Sources Short bio on European artists Terryl L. Givens. '"People of Paradox: A History of Mormon Culture''. (Oxford: University Press, 2007) p. 338. Category:1935 births Category:Italian artists Category:Italian Latter Day Saints Category:Latter Day Saint artists Category:Living peopleQ: $scope.message not able to display text value I created an empty MVC5 web application and trying to display a message in the view which is returned from the external javascript file. @{ ViewBag.Title = "Index"; Layout = null; } <html ng-app="myApp"> <head> <script src="https://cdnjs.cloudflare.com/ajax/libs/angular.js/1.7.8/angular.min.js"></script> <script src="~/Scripts/myscript.js"></script> <title>My AngularJS Page</title> </head> <body> <div ng-controller="myController"> {{ message }} </div> <div></div> </body> </html> I have created my angularjs code in external js file and referenced it in my view. var myApp = angular.module('myModule', []); var myController = function($scope) { $scope.message = "Hello from AngularJS"; } myApp.controller("myController", myController); Instead of displaying "Hello from AngularJS" its just displaying {{ message }}, any clue on what i am missing here? A: ng-app="myApp" is wrong. your module name is myModule. then you should replace it to ng-app="myModule". 1.. Introduction ================ Measuring DNA damage is a key step in a broad range of biomedical research studies. Among several methods of detecting DNA damage, the comet assay, being very simple, cheap and not requiring sophisticated high-cost equipment, has been most widely adapted and used. This method was first described by Ostling and Johanson in 1984 as a single cell gel electrophoresis method \[[@b1-ijms-15-06086]\] and involved embedding cells into agarose gels, followed by lysis and electrophoresis. Stained with acridine orange, the resulting cells resembled comets giving rise to the term "comet assay" and that has become the common name for the assay. Indeed, the intact high-molecular weight genomic DNA does not migrate in the agarose gel electrophoresis forming the "head" of a comet, whereas damage-relaxed DNA loops and DNA fragments migrate away from the head forming the "tail" of the comet. The originally described method consisted of neutral pH lysis and electrophoresis. In 1988 Singh *et al*. developed an alkaline version of the comet assay carried out at pH \> 13, allowing for detection of DNA single strand breaks and alkali-labile sites \[[@b2-ijms-15-06086]\]. The alkaline version of the assay allowed detecting DNA damage produced by as low as 25 cGy. Currently, there are numerous comet assay modifications developed for the detection of very specific DNA lesions and their repair rates, such as single- and double-strand breaks, various base lesions, DNA cross-links, DNA-protein cross-links, *etc*., in many cell types \[[@b3-ijms-15-06086]--[@b9-ijms-15-06086]\]. To achieve high method sensitivity, high quality visualization and imaging of comets is required. This represents a limitation to its widespread use since many laboratories are not equipped with fluorescence microscopes and high-sensitivity CCD cameras for capturing fluorescent images of DNA comets. The only known method of staining and visualizing DNA comets for bright-field microscopy is a modified silver staining method \[[@b10-ijms-15-06086]--[@b12-ijms-15-06086]\]. However, the modified silver staining protocol consists of multiple sensitive steps prone to variation and is not easy to conduct in small laboratories which do not have the money to purchase relatively expensive commercial kits. In this report we show, for the first time, that DNA comets can effectively be stained with an inexpensive and versatile Giemsa stain (azur-eosin-methylene blue solution) widely used in many cyto- and histochemical applications. The sensitivity of Giemsa staining for the comet assay was sufficient not only for the visualization of the comets, but also for imaging and analysis by specific comet assay software. 2.. Results and Discussion ========================== In 2003, Fernandez *et al*. reported the use of a commercially available version of the Romanowsky stain, Diff-Quick, for DNA staining in the sperm chromatin dispersion test \[[@b13-ijms-15-06086]\]. A year later, they used Wright staining for the same purpose \[[@b14-ijms-15-06086]\]. Both staining methods allowed visualization of freely moving DNA loops around sperm cells. We were intrigued as to whether Giemsa staining, which is similar to the Diff-Quick and Wright stains, could be used for DNA staining in the comet assay. As an object of experimentation in this study, human peripheral blood lymphocytes were chosen. These cells represent a convenient model and are often used in biomedical research involving the comet assay \[[@b15-ijms-15-06086]\]. Isolated and agarose-embedded lymphocytes were exposed to X-ray irradiation with 1--6 Gy doses. Following the standard comet assay procedures (cell lysis, DNA unwinding, electrophoresis and neutralization), the comets were fixed in 70% ethanol. Replicate slides were stained in parallel with either highly sensitive fluorescent dye SybrGreen I or conventional Giemsa stain. Shown in [Figure 1](#f1-ijms-15-06086){ref-type="fig"} are representative microphotographs of the comets generated from the control non-irradiated cells ([Figure 1a,d](#f1-ijms-15-06086){ref-type="fig"}) and cells irradiated with either 3 Gy ([Figure 1b,e](#f1-ijms-15-06086){ref-type="fig"}) or 6 Gy ([Figure 1c,f](#f1-ijms-15-06086){ref-type="fig"}). DNA comets stained with SyrbGreen I are shown in panels [Figure 1a--c](#f1-ijms-15-06086){ref-type="fig"}, whereas Giemsa-stained comets are shown in panels [Figure 1d--f](#f1-ijms-15-06086){ref-type="fig"}. As expected, irradiation of the cells produced dose-dependent increases in the fraction of DNA that was electrophoretically-mobile. It is evident from [Figure 1](#f1-ijms-15-06086){ref-type="fig"} that the appearance of the comets visualized by SybrGreen I and by Giemsa are similar. DNA in the comet tails stained with Giemsa was readily visualized. It is noteworthy that the color of Giemsa-stained comets varied from dark blue in centers of the comet heads to pink-purple in the tails. This color variation is related to the concentration of DNA and its conformation. Interestingly, the coloring of Giemsa-stained comets was reminiscent of color patterns typically observed in the G-banding assay, the technique of Giemsa staining of condensed chromosomes following a treatment with trypsin or alkali, resulting in different coloration of the active euchromatin *vs*. inactive heterochromatin \[[@b16-ijms-15-06086]\]. It seems possible that Wright-Giemsa staining may provide additional information about the structure of DNA in various components of the DNA comets. Next, to quantify the amount of DNA damage we analyzed the comets obtained with SybrGreen I *vs*. Giemsa staining using CASP 1.2.2 software (CASPlab, Wroclaw, Poland). The choice of this particular comet assay software was mostly dictated by the fact that it is freely available for download on the Internet (<http://casplab.com>), which is yet another factor allowing positioning of our modification of the comet assay as an affordable alternative for low-budget laboratories. A software snapshot shown in [Figure 2](#f2-ijms-15-06086){ref-type="fig"} demonstrates an example of the analysis of a Giemsa-stained comet using CASP software. DNA damage produced in human peripheral blood lymphocytes by various doses of X-rays was quantified using either SybrGreen I or Giemsa stain. The resulting dose response curves are presented in [Figure 3](#f3-ijms-15-06086){ref-type="fig"}. The regression analysis of the data resulted in linear fits for both staining protocols (*R*^2^ \> 0.977). The detailed results of the regression analysis are presented in [Table 1](#t1-ijms-15-06086){ref-type="table"}. The slope coefficients (*b*) in linear regression equations (*y* = *a* + *bx*, where "*y*" is the percentage of DNA in the comet tails and "*x*" is dose in Gy) define the rate of increase in DNA damage as a function of dose. The SybrGreen I results showed \~1.2-fold higher slope coefficient compared to the Giemsa results (Donor \#1: *b*(SybrGreen I)/*b*(Giemsa) = 1.24; Donor \#2
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captured.at(i))<=2)) { consecutive=consecutive+1; } } } } But when i=0 and j=18 after that it throws the following error: terminate called after throwing an instance of'std::out_of_range' what(): vector::_M_range_check A: The problem is that you are using looping from 0 to N when valid indices are 0 to N - 1. This is why you are getting an exception on the last iteration: std::vector::at performs bound checking, if you are out of bounds then an std::out_of_range is thrown. You need to change your loop's condition to <, not <=. for (int i = 0; i < x_captured.size(); i++) { for (int j = 0; j < y_captured.size(); j++) { ... } } A: for (int i=0;i<=x_captured.size();i++) { for (int j=0;j<=y_captured.size();j++) You should change the <= to < and try again. Example array named Billy : Size : 5 but last index is 4. Get it? :) Q: License for library developed with commercial program I'm developing a commercial application that largely depends on the functionality of a library that will be developed with it. I'd like to open-source this library, because it offers functionality that is not found elsewhere and can be useful in other applications. However, I will also use it in my own commercial application. I don't want to publish the source of the main application, but it is definitely not a derived work (think of calculator app using GPL licensed library to calculate sine). And if someone else commercially uses the library, I want to require them to publish any changes made. Is the GPL license suitable for this or is LGPL perhaps what I need? A: Since you are the author, you can give yourself the library under different terms from what you give the library to others (and you can give it under different terms to various others). As long as you are the only author or get all contributors agree to the special terms for you (you'd need good lawyer to write the agreement so that it's valid across the world though), you can give the library out under any terms you want. This is what Trolltech has been doing for long years with Qt. It was GPL or commercial, so GPL applications like KDE could use it free, but if you wanted to write commercial application, you had to pay for it. So if you want to get some advantage of the library, you can use that model too. Otherwise you have to use LGPL; A calculator using GPL library to calculate sine definitely and unambiguously is a derived work of the library and must be shipped under GPL. Also don't forget that LGPL only excludes dynamically linked objects. If you don't like that, either use Mozilla Public License or GPL with library use exception like libgcc has, or one of the yet more permissive ones, i.e. MIT/X, new BSD or (as mentioned in comments) Apache License or Eclipse Public License (the later two are lately popular because they cover patent grants). Derived work note: Everything that links to a GPL library has to be covered by it. Even things that don't directly depend on it. E.g. if you have GPL library "g" and another library "h" and link them both to application "i", you have to provide source not just for application "i", but also for library "h" that does not depend on "g"! That's because the linked binary is a derived work of the library "g" (for the binary it's obvious) and GPL requires that if you give that derived work to somebody, you have to give everything it contains under GPL except vaguely defined "system libraries". So it includes library "h" that itself knows nothing about "g"! MPL note: Looking at Mozilla Public License I am not really sure what it covers. I think it does not cover larger software that includes the derived work, but I am not sure. Machine learning for SEO : how to predict rankings with machine learning In order to be able to predict position changes after possible on-page optimisation measures, we trained a machine learning model with keyword data and on-page optimisation factors. With the help of this model, we can now automatically analyse thousands of potential keywords and select the ones that we have good chances on reaching interesting rankings for, with just a few simple on-page optimisations. At the end of this article, we share the entire source code of this machine learning SEO experiment with you, so that you can try it out yourself! Would you like to read or share this article in a different language? There are German and French translations of this article available. The rise of machine learning in SEO Google has been working on implementing machine learning into their products and services for a while now. With the help of machine learning, they are able to achieve things that would be very difficult or even impossible to do without it. As SEOs, we might be watching this development with a bit of fear. If machine learning is applied to search algorithms, these algorithms get more and more complex and more difficult to understand, which makes our jobs significantly harder. But why don’t we just use machine learning for SEO, in order to keep up with Google? If SEO gets harder because of machine learning, the best way to tackle this challenge is by using machine learning ourselves, right? In this post, we will show you, with the help of a practical example, how you can use machine learning to improve your search engine optimisation efforts. The case – Identifying keywords with high ranking potential by predicting position changes after optimisations As SEOs, whenever we want to find keyword data, there are lots of great tools at our disposal. The challenge is not finding keywords, but analysing and prioritising them. Let’s start by looking at the keyword data SEMrush gives us for our example website www.barf-alarm.de. We are interested in keywords we are already ranking for, that have high search volumes. As you can see in the screenshot, SEMrush already provides us with a high number of keywords (more than 1100) for the very nichey topic of the example website. By adding keywords that our competitors rank for, but we don’t, we can easily extend this keyword set to more than 3600 keywords: This is still not a very big number of keywords compared to analyses for bigger websites or broader topics, but it is already an amount that would be very challenging to analyse manually. Still, we need to filter these keywords in order to find out which ones are relevant and which ones we have chances of getting a top 10 position for by optimising certain pages on our website. Let’s do it the machine learning way! Our goal is to identify for which of the 3600 keywords that we have collected, a top 10 position is possible. Using machine learning to identify ranking potential – step by step Step 1: Thinking about how we would do this task manually If we wanted to filter our list of 3600 keywords down to a handful of keywords with high ranking potential manually, we would probably look at metrics like search volume and CPC in order to get a feeling for the competitive situation of every keyword. High search volumes and high CPCs usually indicate high competition for a keyword, which makes it more difficult to achieve good rankings. We can also analyse our competitors. If a very similar competitor is ranking in the top 10 for a keyword we are targeting, it is likely that we can achieve such a ranking as well. Last but not least, we can have a look at on-page optimisation factors. If one of our pages is already really well optimised for a certain keyword, but only ranking on page two or three, it is going to be very difficult to improve the rankings further with on-page optimisation measures. If, on the other hand, we don’t have a page that is targeting a keyword or only a page that isn’t very well optimised, it is more likely that we can reach the top 10 for this keyword with on-page optimisation measures. We can use the same data that we would normally analyse manually to train our machine learning algorithm. Let’s have a look at the next steps to learn how this works. Step 2: Gathering and transforming the data we need Now we need to collect the data that we would normally use to perform the manual analyses described above. For this experiment, we use SEMrush’s API to pull data about all of the keywords our example website and its competitors are ranking for: After collecting this data, we crawl all of the ranking pages of our example website and the competitors’ websites and check if the phrase the page is ranking for is contained in the title, content, URL path or domain of the ranking page. We save the information about this as a number, because the machine learning algorithm we are using only works with numbers and doesn’t accept text as an input. So, for example, if all words of the phrase “barfen fleisch” that a page ranks for are found in the title tag of that page, we save the value “1” in “title_found”. If only one of the words (50% of all words) is found, we save
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als, and when I got home, I accidentally spent 2 more hours reading the Fantastic Beasts book over and over and already longing for the sequel. I loved most things about the movie, but being a sucker for props I was instantly drawn to Newt's suitcase in the "muggle mode". Just finding the location of the map shown in the movie took weeks, but oh was it worth it! I made this miniature as a christmas tree ornament for my cousin that year, but didn't end up posting the photos at that time. But, today's the day! After watching the Crimes of Grindelwald I'm working on adding some projects based on the new movie as well, but that's a future surprise... In the mean time, enjoy! Supplies:First Class Hospital Wards by Priestmangoode If hospital interiors looked anything like these first class hospital wards, I don't think I would feel as...hesitant...as I usually am about stepping inside these healing buildings. I think most people feel the way I do; however, I would argue that I'm more sensitive than others. Designed by PriestmanGoode, these first class hospital wards would completely revolutionize hospitals as we know them if actually moved forward with. As of right now, however, it's simply a concept.4 min read Today Apple Pay accounts for 70% of the world’s card payment transactions, making the Apple payment gateway a must-have for any digital business. Additionally, it allows you to accept overseas payments since this service is available in over 20 countries. So what are you waiting for? Let us show you how you can implement Apple Pay onto your own mobile application. The reasons for Apple Pay integration As noted above, Apple Pay is a leader within the credit card payments market. It’s a simple one-touch way to make online payments, the simplicity of which, helps increase your customers’ satisfaction rate. Especially, if we talk about your Minimal Viable Product. In Q3 of 2019, Apple reported record profits of almost 54$ billion. This number was led by services, like Apple Pay, showing just how huge their market is! At the moment 90% of all contactless payments in the USA are made by Apple. It’s commonly integrated into apps. In 2019 alone 10 billion contactless payments were made using Apple Pay. It’s popular, with over- 253 million people already using this payment method. Benefits for your customers Guaranteed security. According to statistics, 50% of users are concerned about the security of their personal data, which is a good reason to set up Apple Pay! It uses device-specific numbers and codes, meaning it is almost impossible to copy. It helps you create an easy and quick user experience for your customers. A smooth one-click payment transaction is so much better than empty text inputs to enter credit card data. Especially, when you would need to save your details on the website in order to have a one-click payment on your return. In 2019 it’s essential that you are implementing the best features since requirements stage as user expectations are a lot higher these days. How to set up Apple Pay in 28 steps I’ve used a React Native framework for front-end and Laravel for back-end. The general workflow to implement Apple Pay is as follows: Create a Merchant account. Set up an Apple Pay configuration for the project in your Xcode. Then go to iTunes Connection. There you will need to create a sandbox user. Add a test card. Create a test request to make a payment. Handle the result. However, the details are a little more complicated. Below we will outline step by step how to set up Apple Pay: 1. Create an account to enable Apple Pay in your mobile application. Follow the official setup steps. 2. Next set up your server, not forgetting to first check out the official requirements. In the server configuration file, you will need to add one of the possible Cipher Suite referenced above. Take a look at our example configuration for Nginx. 3. Next, you need to set up your work environment. As always, check the official requirements first. 4. Here is an example of how to add the Apple Pay payment button. Using the v-if directive you can check whether you have successfully installed Apple Pay sessions and whether users can now make payments using Apple Pay. 5. Now let’s create a certSigninRequest.certSigninRequest: Open Keychain Access on your Mac (located in Applications/Utilities). Open Preferences and click Certificates. Make sure both the Online Certificate Status Protocol and Certificate Revocation List are set to Off. Choose Keychain Access > Certificate Assistant > Request a Certificate Authority. N.b. If you have your private key selected when you do this, the CSR won’t be accepted. Make sure you do not have a private key selected. Next, enter your user email address and user name. Use the same address and name that you used to register in the iOS Developer Program. A CA Email Address is required. Select the option “Save to disk” and “Let me specify key pair information” and click Continue. Specify a file name and click Save. 6. After Signing in you can register for your Apple Pay Developer account at https://developer.apple.com/ 7. Go to menu “Certificates, IDs & Profiles”. 8. Click on the button ‘add new certificate’. 9. Then choose the options Apple Pay Merchant Identity Certificate. 10. Now choose the required Merchant from the list of those currently available. 11. Go to menu “Identifiers” and filter by Merchant IDs. 12. Choose the previously created Merchant. 13. Next, create an Apple Pay Payment Processing Certificate. 14. After the creation of a certificate, you will need to upload the.csr extension which is an ECC encrypted file. We receive this file from our payment system (in our example we work with the bank, so screen made there) 15. Add and verify the domain, following the instructions on the screen. Pay attention every time you renew an SSL Certificate, as you will need to verify the domain each time. 16. If you missed step 5 go back and take a look at how to create a certSigninRequest.certSigninRequest. If you haven’t created one yet, now is the time using encryption RSA:2048. 17. Download your previously created certSigninRequest.certSigninRequest and then download merchant_id.cer. 18. Import received merchant_id.cer in Keychain (it required to export file in.p12). 19. In category Certificates in Keychain, you need to export the certificate using format.p12. 20. Generate merchantIdentityCert from the received file using the command below:openssl pkcs12 -in your_cer_name.p12 -out you_key_cert_name.pem -clcerts. 21. Enter the password that was entered during export merchant_id.cer in.p12. 22. Enter PEM pass phrase – this will be the key to the generated merchantIdentityCert. 23. Put the generated merchantIdentityCert in the project’s folder. 24. Use merchantIdentityCert in the body of the request for validation Apple Pay Session. 25. Example of the request where we see: Use the answer to complete Merchant validation. Take a look: 27. Create the Apple Pay button in accordance with the requirements here in the section “Display an Apple Pay button” 28. Code listing in Apple Pay using Payment Request API Summary Connecting Apple Pay in application is a pain point for many developers. There too man reasons why it’s actually is a pain! The lack of clear guidelines the main one. As well as complicated requirements by Apple. That’s why SpdLoad’s team is happy to share with you our expertise in implementing Apple Pay. It saves you a it saves you a huge amount of resources and boost up own in-house development level. The main challenge you may face is adopting our guideline to your personal requirements. Such as different payment gateways. We would be happy to help you with development of your application! Feel free to ask question, comment and share. We hope you enjoy it!You are viewing the original copy of this page You are viewing your personal edited copy of this page JSON Parser Speeds and Correctness FPJson The JSON parser included with the Free Pascal Compiler and part of the FCL. JsonTools A new JSON parser described here and implemented in a single self contained class available on GitHib LkJSON A long standing JSON parser written by Leonid Koninin and hosted on SourceForge JsonStorage A class within a business ORM claiming to support JSON parsing and hosted on GitHib Test Sections Test Preparation Library Number of Files Size on Disk (including comments) Warnings or Hints FPJson 4 files 127 KB Both JsonTools 1 file 33 KB None LkJSON 1 file 67 KB Both JsonStorage 2 files 32 KB Warnings Speed Tests Correctness Tests A Detect invalid JSON by substituting a colon where a comma should have been placed. B Handling blank
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Scrum daily meetings: difference between Reporting and Check-In? The "Three Questions" for Scrum dailies sound to me like a perfect instruction, to waste 15 minutes with useless status reporting: What have you completed since the last meeting? What do you plan to complete by the next meeting? (impediments...) It often goes in the way of: "Yesterday I did task X, today I will work on Y", or, more often, "I am still working on task Z", on almost every day of the sprint. Sometimes with more or less technical details. Some people say it's for Check-In instead of Reporting, but is there a difference? Apart from Reporting possibly leading to immediate rating. And if, what is the difference? These reports every day make little sense to me, as long as there are no important news, or impediments to be bookmarked for later debate/solving. They have a tendency to become 10 or 15 minutes of boredom. Or is there a different meaning in the first 2 of the 3 questions, that qualifies "check-in" in a different way? A: Scrum considers the Daily Scrum to be an inspection and planning meeting. The purpose is to inspect the work done against the Sprint Goals and to plan the next day's worth of work. The three questions are just one method of running a Daily Scrum and are not required. The Scrum Master should be coaching the Development Team on an effective way to execute the Daily Scrum such that the objectives of inspecting progress against the Sprint Goals, inspecting progress against the Sprint Backlog, and adapting or planning for changes to be able to achieve the Sprint Goals are met. The 15 minute timebox is also a maximum length of time. Depending on the size of your team, it may be shorter. A Development Team in Scrum is between 3 and 9 individuals. A Development Team of 9 people should be able to complete their inspection and planning in 15 minutes. A team of 3 may need a shorter period of time to do the same. Another key element from the Scrum Guide is that the "Development Team or team members often meet immediately after the Daily Scrum for detailed discussions, or to adapt, or replan, the rest of the Sprint's work". Some things may come up in the Daily Scrum that require additional work to figure out what to do or may need the involvement of the Product Owner. In these cases, the problem should not be addressed immediately in the Daily Scrum, but by the right people after the Daily Scrum. If you are simply "checking in" or "reporting" the status of work, I would consider that to be half of what the Daily Scrum is supposed to be. You should also be looking at the Sprint Goals and finding ways to either meet the Sprint Goals come the end of the Sprint or working with the Product Owner to realign the Sprint Goals to something that is achievable. The Sprint Retrospective is a great opportunity to revisit and reflect on why certain problems came up that impacted the team's work and how to prevent them in the future. Q: Android: how to get list item property with floating context menu item click I have an activity with arraylist declaration private ArrayList<Product> products = new ArrayList<Product>(); and inside onCreate products.add(new Product("Product One",100, 1)); products.add(new Product("Product Two",200, 2)); products.add(new Product("Product Three",170, 3)); products.add(new Product("Product Four",220, 4)); ProductAdapter itemsAdapter = new ProductAdapter(this, products); ListView listView = (ListView) findViewById(R.id.list); listView.setAdapter(itemsAdapter); registerForContextMenu(listView); in the Product class: public class Product { private String mProductName; private int mProductPrice; private int mProductId; public Product(String productName, int productPrice, int productId){ mProductName = productName; mProductPrice = productPrice; mProductId = productId; } public String getProductName(){ return mProductName; } public int getProducId(){ return mProductId; } public int getProductPrice(){ return mProductPrice; } } And the adapter is simple to get the name and price of every product and view the list. Now in the activity I create the context menu like this @Override public void onCreateContextMenu(ContextMenu menu, View v, ContextMenu.ContextMenuInfo menuInfo) { super.onCreateContextMenu(menu, v, menuInfo); MenuInflater inflater = getMenuInflater(); inflater.inflate(R.menu.context_menu, menu); } How can I get the long pressed item property like product id after selecting optipn from the context menu using "onContextItemSelected"? A: first set a global variable productId then on the listview long click listener set the product id. take a look at the sample code below. int productId = 0; lv.setOnItemLongClickListener(new AdapterView.OnItemLongClickListener() { @Override public boolean onItemLongClick(AdapterView<?> arg0, View arg1,int pos, long id) { // TODO Auto-generated method stub Product product = (Product)arg0.getAdapter().getItem(position) productId = product.mProductId; return false; } }); Q: Entity Framework Core Class Library build giving error CS7036 I'm sure there's something small and dumb that I'm missing here. When I attempt to build my class library I get the following error: StaticDataHelper.cs(13,16): error CS7036: There is no argument given that corresponds to the required form al parameter 'options' of 'StaticDataContext.StaticDataContext(DbContextOptions<StaticDataContext>)' [C:\U sers\bryce\Google Drive\dotnet\libraries\EveStaticData\EveStaticData.csproj] The relevant code block looks like this: public StaticDataContext(DbContextOptions<StaticDataContext> options) :base(options) { } I was attempting to follow this guide Microsoft put out. I've created a GitHub repository of my code here and the specific file in question is here. I've checked over the constructor function again and again and all other similar guides/tutorials used the same code. I'm using: EntityFrameworkCore 1.1.2 .netcore 1.1 Let me know if there's any other info that could help. A: You do not need to pass DbContextOptions to both the constructor and to the OnConfiguring() method. Just do it in either the ctor or the OnConfiguring() method. If both are used, OnConfiguring is executed on the supplied options, meaning it is additive and can overwrite options supplied to the constructor argument.+ See here for guidance: https://docs.microsoft.com/en-us/ef/core/miscellaneous/configuring-dbcontext Sample code change that should resolve your issue (if you are not injecting the DBContextOptions from the Startup: public partial class StaticDataContext : DbContext { public StaticDataContext() { } //... protected override void OnConfiguring(DbContextOptionsBuilder optionsBuilder) { optionsBuilder.UseSqlite(@"Datasource=sqlite-latest.sqlite"); } //... } If you are injecting the DbContextOptions via dependency injection, then use the following: public partial class StaticDataContext : DbContext { public StaticDataContext(DbContextOptions<StaticDataContext> options) : base(options) { } //... //Removed as it's being injected in to the ctor via DI //protected override void OnConfiguring(DbContextOptionsBuilder optionsBuilder) //{ // optionsBuilder.UseSqlite(@"Datasource=sqlite-latest.sqlite"); //} //... } Mangaluru, July 19,2016 : A Kala Jatha aimed at creating awareness among the people on the achievements of the state government was inaugurated by Deputy Commissioner A.B. Ibrahim at the DC office premises on July 19, Tuesday. The jatha has been organised to mark the beginning of the 4th year of the government in office. In his address, the Deputy Commissioner elaborated on the various welfare schemes launched by the government including the Anna Bhagya, Ksheera Bhagya, Rajeev Arogya Bhagya, Krishi Bhagya etc. He said the 21 day long Yatra organised by the Information Department will travel in various parts of the district. CDs providing information about government schemes will also be played during the jatha, informed Information Officer Khader Shah.# -*- coding: utf-8 -*- # @Author: aaronlai import torch import
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well as anyone without apparatus – as well as philosophy in which I have become perfect in by teaching it. I studied astronomy in a small work but have now got a a geography and atlas of the heavens which I like much better: though I have had it but a short time and have not had much time to study it, yet I am going to bring out with me to Aunt's and devote a half hour each evening in tracing out the constellations. Besides having all my lessons I have read a great deal – I have so many books brought to me by my acquaintances and Mrs. Fling has a great many. I suppose that Father would think I might as well not have read such as Byron's works and Moor's "Lallah Rookh" and several such works – many of Shakespeare's plays. But I have read some useful works too and studied history more than I ever did before. I have just finished Irving's Sketch Book and commenced a very long work called Rural Life in England by Howett. I think that Father would be delighted with it: It contains a great many useful hints to country people. It is a new publication and I think that you could get it in Buffalo. To be sure there is another work by Howett which I hear spoken of very highly and intend reading when I finish the one I am now at; some like it better than the Rural Life, it is Howett's Visits to Remarkable Places. It is a smaller work in two volumes and from what I hear of it I think thee would like it better than the other. How I wish that thee had some of the books that I have not had time to read – but it will take thee a few weeks to read the encyclopedias through and there is anything almost that thee could think of in it and thee gets all that is necessary on any subject without such a long drawn out... round of reading and study. But really my hand is getting tired – I have written all this without stopping 5 minutes. Aunt is asleep so I am alone by myself. I will finish this letter when I go to town. Phila 12th 7 mo. I will now try to finish my letter after so long a time. I am now in town and on second day the 5th of July there was no school as that day was independence. Mrs Fling went to New York to spend a week there and in New Brunswick. There is but a few scholars and we have nice times. Mrs Fling came home on 7th day and has decided to vacate the school tomorrow or next day and then I expect to go out to Aunt's. _Frank Johnson 1792–1844, leader of a band of coloured minstrels. From a lithograph by Hoffy. Courtesy The Historical Society of Philadelphia_ Oh! I had like to have forgot to tell thee about a picnic party I was on a few weeks ago; our "Social Circle" and another called "The Round Table" joined and there were several others invited, in all about 70. We went out to the banks of the Wissohicon, a branch of the Schuylkill about the size of the Catteraugus, and a most romantic place it is. We went in three omnibusses and had Frank Johnson's colored minstrals with us. They rode on the top of the omnibusses and we drove slowly along on the banks of the river and the band played a great many beautiful tunes which sounded beautiful revirbrating from the hill on either side. We passed Girard College and Hill Cemetery and at last arrived at the Falls of the Schuylkill where the gentlemen had ordered an elegant supper. About an hour after supper we had strawberries and cream handed round and everything in such profusion. The ladies were nearly all dressed in white as were also many of the gentlemen – and upon the whole I never enjoyed myself better in my life. I went with the President of our circle, whose name is Robert Knight. They had a great deal of fun introducing me to some that I did not know as "lady presidentress", which was at first rather confusing to me, making me so conspicuous, but I soon got accustomed to it and did not mind it at all. He was also the president of the committee on arrangments, so thee sees I was quite honored. I expect to go on a sailing party up the Delaware or the Schuylkill if nothing happens. I would have gone to Chester last week but I was not in town – they went in an evening on a moonlight excursion – seven of our members went. I was at meeting yesterday morning at Cherry Street and heard a long sermon from George Trueman at Yearly Meeting. I heard Lucretia Mott, the celebrated abolitionist who went to England to the world convention – she is the most eloquent female speaker I have ever heard. I think that I will send a newspaper to thee when I am about leaving here for N.Y. so thee will know and I will write on the margin "I am leaving". It may be that I will send one paper before that but I will not write much on it, perhaps mark some words. Oh I must tell thee how much I know about French – well I can "parli Francais" – talk French... several french phrases... I will bring my French books and have thee and the rest of the children learn it. Thee will find it very different and I think it will be of use to teach thee as it will fix it in my mind. I have a grammer and a book of conversations, and a dictionery and history of Charles the twelvth king of the Sweden, which we have to read and translate. We do not take lessons now. I am going to take my book with me into the country and do some translating while I am there. I went in the evening yesterday to hear a great Universalist minister and was very much pleased with him. His text was the 1st verse of the 15th chapter of Hebrews. Tell Mother that Cousin James has a letter from Aunt Jane some time ago reporting the death of William Greer of Milton. She says that they are well as usual – also tell her that Aunt desired to be remembered to her. Cousin Mary sends her love and says that she is sorry to disappoint you about coming, but there are plenty of more summers and that she thinks that it will certainly not be very long before she makes a visit to Collins. Have you a good garden this summer? And is there much fruit in your part of the country? There is very little here, or in Jersey which is so much noted for its cider and fine fruit: in the neighborhood of New Brunswick it is an entire failure. A young man who visits here and has just returned from the west and has been in Indiana, Ohio and Kentucky says that every thing is very backward in the west, also that in many parts the crops have utterly failed. The market is very high: one thing, the article of butter is 25 cts to 31 cts per lb and eggs 3 fips [ _?_ ] a dozen. There is one thing more that I forgot to tell thee: I have learned to make worsted flowers. Joseph, I want thee to mention something about me taking our school up east this next winter. Tell them I will teach for 12 dollars a month, and if thee will like to go in with me, thee must ask as much more as thee chooses, but I think that thee would make more to teach by thyself. If they will not let me have their school, try and get one for me somewhere and also one for thyself. Be sure and try in good season and not put off, as there are so many applicants for schools. Mrs. Fling said the other day that she would be glad if I would stay and take the place of her principal teacher, who talks of going south. But I think that I can get as good a price at home and have as good a name as Drusilla Allen. She only went six months to Jamestown and I have been a little more than eight months in one of the best schools in Philadelphia. If thee dont try to give me a good name why thee will miss it, thats all. For I am going to teach thee all that I know if nothing happens; and the more I know, the more they will think that thee knows; so dont forget but tell every one how much I have learned and how many advantages I have here. Tell me if thee thinks that my price is too high or too little – if thee can get more, why do so of course; and if they wish us to take less, tell them that you think I will not, but try to get them to wait till I come home. Thee will of course ask more that thee did last winter – thee ought to get 16 to 18 dollars a month, and, if thee can spare the time from the farm, take one for 4 months. Afft sister Maria Write soon. ### _Letter 103_ **Abraham Bell to Maria Wright O'Brien** New York 11 mo 22nd 1841 My dear Maria I was pleased to receive thy kind letter of 27th Ult. and to find thee again reached thy Fathers house in safety. Where no doubt thou wert greeted by all its inmates with much affection. I did not intend to have delayed replying so long. But my many engagements must be my excuse. I percieve by thy letter that you are willing that Joseph should come to New York & make a trial if business should best suit his inclination. I have consulted with the family and we have concluded also to make the trial under the hope that it may result in his benefit and ultimately that it may be useful to his younger
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อลูมิเนียมฟลอยแทนก็ได้ ทาน้ำมันมะกอกที่แม่พิมพ์ ใส่โดว์ลงไปทิ้งไว้ในเตาอีกประมาณหนึ่งชั่วโมงที่อุณหภูมิ 30 ถึง 35°C เมื่อโดว์พองขึ้นให้ทาด้วยน้ำมันมะกอกและโรยเมล็ดงาลงไปบนแป้ง เอาไปอบเป็นเวลา 15 นาที่ ที่อุณหภูมิ 200°C Chinese: 让他们再醒15分钟 现在我要将豆腐块泡在加了蒜粉的酱油里 下一步将面团放在圆形模具中 如果你没有这样的模具，你可以用铝箔纸DIY一下 模具里面涂上橄榄油 将面团压进去，然后让它在30-35°C下休息半小时左右 当面团鼓起来了，涂上橄榄油再撒点芝麻 200°C烤15分钟 Indonesian: Diamkan selama 15 menit Sekarang, aku akan memasukan potongan-potongan tofu dalam kecap dengan bubuk bawang putih Selanjutnya, letakan adonan dalam cetakan bulat Kalau kamu tidak punya cetakan seperti ini, kamu bisa menggunakan aluminium foil dan bentuk menjadi bulat Lapisi bagian dalam cetakan dengan minyak zaitun Tekan adonan dan diamkan selama satu jam dalam suhu 30 to 35°C. Ketika adonan sudah mengembang, lapisi adonan dengan minyak zaitun dan taburkan biji wijen Panggang selama 15 menit dalam suhu 200°C Japanese: １５分ほど休ませます 豆腐をガーリック醤油に漬けます 型に生地を入れます 型がなければ、アルミホイルで代用できます 型の内側にオイルを塗ります 生地を押さえ、３５度前後で６０分程二次発酵します 生地が膨らんだらオリーブを塗り、 ゴマをふりかけます ２００度のオーブンで１５分焼きます Vietnamese: Để bột khoảng 15 phút. Bây giờ, mình sẽ ngâm những miếng đậu phụ trong nước tương với bột tỏi. Kế tiếp, đặt bột trong những khuôn nướng hình tròn. Nếu bạn không có khuôn như vậy, bạn có thể sử dụng lá nhôm và tạo hình cho nó. Quét một chút dầu ô-liu ở bên trong khuôn. Nhấn bột xuống và để yên trong một tiếng với nhiệt độ từ 30 đến 35 độ C. Khi bột nở, phủ nó với dầu ô liu và rắc ít hạt mè. Nướng nó khoảng 15 phút tại 200 độ C. Turkish: 15 dakika dinlenmelerine izin verin. Şimdi tofu parçalarının sarımsak tozu ile soya sosu içinde ıslanmasına izin vereceğim. Daha sonra hamuru yuvarlak pişirme kalıplarına yerleştirin. Eğer böyle kalıplarınız yoksa, Sadece alüminyum folyoyu kullanabilir ve şekillendirebilirsiniz. Kalıpların içini zeytinyağı ile kaplayın. Hamuru aşağı bastırın ve 30 ila 35 ° C'de yaklaşık bir saat boyunca dinlenmeye bırakın. Hamur kabardığında, zeytinyağı ile kaplayın. ve biraz susam serpin. 200 ° C'de 15 dakika pişirin. German: Lasst sie für etwa 15 Minuten ruhen. Nun werde ich die Tofustücke in Sojasauce, die mit Knoblauchpulver vermischt ist, einweichen lassen. Platziert den Teig als nächstes in runden Backformen. Wenn ihr solche Formen nicht besitzt, könnt ihr auch geformte Aluminiumfolie verwenden. Streicht die Innenseiten der Formen mit Olivenöl ein. Drückt den Teig nach unten und lasst ihn für ungefähr eine Stunde bei 30-35°C ruhen. Wenn der Teig aufgeht, bestreicht ihn mit Olivenöl und streut einige Sesamsamen darauf. Backt die Brötchen für 15 Minuten bei 200°C. English: Let them rest for about 15 minutes. Now, I'm going to let the tofu pieces soak in soy sauce with garlic powder. Next place the dough in round baking molds. If you don't have molds like this, you can just use aluminum foil and shape it. Coat the inside of the molds with olive oil. Press the dough down and then let it rest for about an hour at 30 to 35°C. When the dough rises, coat it with olive oil and sprinkle some sesame seeds. Bake it for 15 minutes at 200°C. Slovak: Nechajte ich odpočívať po dobu 15 minút. Teraz, nechám kúsky tofu absorbovať sójovú omáčku s cesnakovým práškom. Ďalej položte cesto do okrúhlych foriem na pečenie. Pokiaľ nemáte takéto formy, môžete použiť alobal a vytvarovať ich. Potrite vnútornú stenu formy olivovým olejom. Stlačte cesto nadol a nechajte na hodinu odpočívať pri 30 až 35°C. Keď sa cesto zdvihne, potrite ho olivovým olejom a posypte sezamovými semiačkami. Pečte 15 minút pri 200°C. Spanish: Déjalos reposar unos 15 minutos. Ahora, voy a dejar remojar las piezas de tofu En salsa de soja con ajo en polvo. Luego coloque la masa en moldes para hornear redondos. Si no tienes moldes como este, Puedes usar papel de aluminio y darle forma. Cubrir el interior de los moldes con aceite de oliva. Presiona la masa hacia abajo y luego déjala reposar. Durante aproximadamente una hora entre 30 y 35
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79, 11, 1186, 30, 1186, 18911, 10, 55, 2088, 2796, 79, 11, 1186, 30, 1186, 26673, 10, 55, 1194, 2796, 79, 11, 1186, 30, 1186, 1967, 10, 55, 2088, 2796, 79, 11, 1186, 30, 1186, 15220, 10, 30386, 575, 27346, 3031, 313, 3763, 2673, 17984, 313, 3547, 2673, 3712, 313, 3655, 2673, 11335, 313, 1976, 2673, 575, 33090, 15144, 313, 1839, 2673, 10655, 313, 1619, 2673, 11, 17, 15, 8972, 11, 746, 313, 1630, 2673, 1706, 313, 1099, 2673, 17, 15, 3566, 19711, 313, 10526, 10, 3832, 15, 938, 313, 1036, 15, 1099, 10, 3011, 15, 3566, 313, 1093, 15, 2950, 2888, 17, 15, 8972, 11, 2417, 15, 1731, 313, 1036, 15, 18, 10, 3439, 15, 4185, 313, 1036, 15, 1812, 10, 17, 15, 2511, 52, 37681, 3719, 2385, 15, 2227, 313, 1093, 15, 805, 10, 2537, 15, 2511, 313, 1166, 15, 1438, 10, 17, 15, 1857, 3439, 15, 23, 313, 746, 15, 2950, 10, 3046, 15, 4148, 313, 1036, 15, 2358, 10, 17, 15, 41040, 8683, 5377, 24, 15, 1540, 313, 20, 15, 2787, 10, 25, 15, 2922, 313, 20, 15, 3571, 10, 17, 15, 15497, 15, 746, 313, 21, 15, 1706, 10, 25, 15, 26, 313, 21, 15, 2125, 2888, 17, 15, 8897, 11, 3837, 2230, 7140, 575, 41225, 14840, 313, 2417, 2673, 22981, 313, 3046, 2673, 3011, 313, 3593, 2673, 12231, 313, 2691, 2673, 575, 52, 19785, 11838, 313, 1857, 2673, 18795, 313, 3156, 2673, 17, 15, 1099, 1012, 313, 746, 2673, 746, 313, 1047, 2673, 17, 15, 1867, 575, 27004, 37, 1540, 313, 938, 2673, 3832, 313, 1166, 2673, 17, 15, 23260, 313, 740, 2673, 1797, 313, 1010, 2673, 17, 15, 1166, 575, 12558, 24298, 27000, 2526, 313, 1797, 2673, 2090, 313, 746, 2673, 17, 15, 3357, 1047, 313, 938, 2673, 1731, 313, 938, 2673, 17, 15, 2055, 575, 30458, 14881, 13382, 1701, 1363, 1348, 313, 25, 2673, 2405, 313, 25, 2673, 17, 15, 43438, 313, 740, 2673, 1508, 313, 1166, 2673, 17, 15, 1093, 575, 1779, 3462, 2798, 4433, 1630, 313, 25, 2673, 746, 313, 22, 2673, 17, 15, 41532, 1036, 313, 1508, 2673, 1036, 313, 805, 2673, 11, 17, 15, 20826, 11, 575, 1779, 3462, 11900, 4433, 1671, 313, 883, 2673, 1630, 313, 24, 2673, 17, 15, 2693, 3245, 313, 21, 2673, 24, 313, 22, 2673, 17, 15, 3141, 575, 23644, 9492, 2433, 25, 313, 19, 2673, 1508, 313, 23, 2673, 11, 17, 15, 12058, 11, 20, 313, 21, 2673, 740, 313, 24, 2673, 17, 15, 1839, 575, 25925, 18820, 897, 16899, 313, 2526, 2673, 19136, 313, 3571, 2673, 17, 15, 1857, 1549, 313, 2691, 2673, 12224, 313, 2787, 2673, 17, 15, 20, 575, 2946, 12341, 366, 3302, 23945, 4918, 18804, 313, 3439, 2673, 21553, 313, 1967, 6, 48744, 470, 15, 361, 12434, 313, 3011, 2673, 2417, 313, 1449, 2673, 17, 15, 13269, 3233, 403, 3559, 347, 1180, 11767, 390, 1599, 313, 3871, 2888, 27004, 37, 11, 28289, 37534, 12698, 2728, 13, 475, 52, 37681, 11, 3759, 446, 1245, 7928, 32337, 4868, 13, 475, 8683, 5377, 11, 18374, 1624, 1963, 4433, 6803, 13, 475, 55, 2088, 11, 23780, 300, 1080, 14, 12534, 18277, 13, 475, 55, 1194, 11, 23780, 300, 1080, 14, 12534, 32122, 706, 1406, 348, 5895, 11, 81, 11, 1318, 1186, 4713, 1186, 17, 15, 1762, 310, 4860, 275, 36037, 280, 5810, 187, 187, 30466, 6973, 275, 253, 28529, 285, 12820, 27361, 403, 2011, 275, 5270, 575, 60, 19, 1084, 10297, 19, 910, 709, 14, 881, 568, 2420, 986, 575, 395, 14117, 1873, 544, 20, 1084, 13270, 20, 910, 709, 14, 881, 568, 8236, 7129, 25311, 7891, 369, 2169, 275, 1363, 342, 657, 2088, 2429, 281, 1363, 342, 49509, 275, 253, 28529, 11077, 15, 3235, 575, 19, 30466, 6973, 273, 1363, 19932, 7639, 11077, 11, 49, 11, 1318, 31780, 11077, 11, 49, 11, 1318, 55, 1194, 2796, 79, 11, 1186, 30, 1186, 18911, 10, 55, 2088, 2796, 79, 11, 1186, 30, 1186, 26673, 10, 55, 1194, 2796, 79, 11, 1186, 30, 1186, 1967, 10, 55, 2088, 2796, 79, 11, 1186, 30, 1186, 15220, 10, 41430, 327, 8651, 23815, 1012, 313, 25, 283, 938, 10, 1012, 313, 25, 283, 1731, 10, 17, 15, 1671, 1093, 313, 1012, 283, 1717, 10, 1166, 313, 883, 283, 1717, 10, 17, 15, 1508, 41430, 275, 253, 25311, 1797, 313, 1010, 283, 1706, 10, 1423, 313, 1012, 283, 1812, 10, 17, 15, 2090, 1348, 313, 1036, 1969, 5345, 10, 1423, 313, 1047, 283, 1671, 10, 17, 15, 20, 43007, 7891, 4590, 313, 1717, 2673, 16607, 313, 1449, 2673, 11, 17, 15, 5525, 11, 1093, 313, 1731, 2673, 2950, 313, 1706, 2673, 17, 15, 1508, 1845, 7186, 432, 49509, 281, 657, 2088, 1867, 313, 805, 2673, 33301, 33301, 24, 313, 740, 2673, 315, 3233, 403, 3559, 347, 1180, 11767, 390, 8876, 313, 2388, 42899, 2491, 2888, 43007, 11, 4458, 3134, 9776, 16062, 28, 475, 55, 2088, 11, 23780, 300, 1080, 14, 36597, 456, 367, 11312, 9409, 28, 475, 55, 1194, 11, 23780, 300, 1080, 14, 36597, 456, 1535, 2679, 706, 1406, 348, 5895, 11, 81, 11, 2193, 1186, 4713, 1186, 17, 15, 1762, 403, 4860, 275, 36037, 982, 5810, 187, 187, 510, 1783, 273, 18124, 1975, 4342, 4950, 247, 2169, 4294, 273, 475, 15886, 13385, 11, 26105, 15, 275, 1363, 342, 657, 2088, 2429, 281, 1363, 342, 49509, 275, 253, 12820, 11077, 15, 24646, 13, 475, 36, 4905, 67, 1434, 4107, 1504, 2886, 11, 369, 1119, 625, 7208, 275, 49509, 84, 685, 275, 657, 2088, 84, 275, 253, 12820, 11077, 313, 3235, 575, 60, 20, 1084, 10297, 20, 910, 709, 14, 881, 568, 2420, 2536, 21594, 10047, 273, 18124, 1975, 4342, 875, 28529, 285, 12820, 27361, 403, 2011, 275, 14117, 1873, 544, 21, 1084, 13270, 21, 910, 709, 14, 881, 568, 8236, 7129, 575, 5305, 1830, 2193, 17751, 432, 470, 281, 884, 323, 1363, 342, 49509, 285, 432, 470, 281, 1903, 323, 1363, 342, 657, 2088, 275, 253, 28529, 11077, 15, 496, 253, 12820, 11077, 13, 13874, 1830, 2193, 17751, 432, 374, 281, 884, 323, 1363, 342, 49509, 285, 432, 337, 281, 884, 323, 1363, 342, 657, 2088, 15, 3235, 575, 20, 25810, 4193, 1975, 4342, 19932, 7639, 11077, 49, 1318, 31780, 11077, 11, 49, 11, 1318, 55, 1194, 2796, 79, 11, 1186, 30, 1186, 18911, 10, 55, 2088, 2796, 79, 11, 1186, 30, 1186, 26673, 10, 55, 1194, 2796, 79, 11, 1186, 30, 1186, 1967, 10, 55, 2088, 2796, 79, 11, 1186, 30, 1186, 15220, 2888, 998, 46782, 36500, 11, 1036, 313, 22, 2673, 1348, 313, 24, 2673, 17, 15, 30965, 313, 20, 2673, 22, 313, 21, 2673, 18, 11, 998, 257, 302, 3838, 31911, 33673, 25400, 11, 746, 313, 23, 2673, 805, 313, 20, 2673, 17, 15, 41280, 313, 23, 2673, 23, 313, 21, 2673, 17, 15, 3566, 6784, 4576, 25, 313, 19, 2673, 25, 313, 19, 2673, 17, 15, 40379, 313, 18, 2673, 18, 313, 18, 2673, 18, 3338, 4576, 2526, 313, 1797, 2673, 1438, 313, 1423, 2673, 17, 15, 24, 1812, 313, 26, 2673, 1797, 313, 1010, 2673, 17, 15, 1166, 11, 52, 1000, 255, 571, 2304, 707, 46874, 11, 805, 313, 21, 2673, 1036, 313, 21, 2673, 17, 15, 33291, 313, 21, 2673, 22, 313, 21, 2673, 18, 11, 35875, 31911, 38143, 11, 2787, 313, 1099, 2673, 2511, 313, 1348, 2673, 17, 15, 2691, 938, 313, 1717, 2673, 1717, 313, 1797, 2673, 17, 15, 1099, 11, 19710, 316, 6385, 5280, 261, 11, 1010, 313, 22, 2673, 1047, 313, 21, 2673, 17, 15, 42310, 313, 21, 2673, 22, 313, 21, 2673, 18, 11, 44, 282, 1768, 50019, 36500, 11, 2385, 313, 1010, 2673, 3357, 313, 1047, 2673, 17, 15, 25, 746, 313, 1012, 2673, 1229, 313, 1423, 2673, 17, 15, 883, 11, 18853, 358, 15019, 316, 3108, 12586, 3348, 11, 1237, 313, 740, 2673, 1099, 313, 24, 2673, 17, 15, 13397, 313, 23, 2673, 23, 313, 21, 2673, 17, 15, 3566, 11, 32629, 31977, 14347, 11, 1787, 313, 805, 2673, 1449, 313, 883, 2673, 17, 15, 49002, 313, 24, 2673, 26, 313, 24, 2673, 18, 11, 15886, 13385, 11, 26105, 15, 1671, 313, 883, 2673, 2950, 313, 805, 2673, 17, 15, 45225, 313, 23, 2673, 1797, 313, 1010, 2673, 11, 17, 15, 21045, 36, 4905, 67, 1434, 4107, 1504, 2886, 11, 24, 313, 19, 2673, 23, 313, 19, 2673, 17, 15, 22, 2759, 313, 23, 2673, 18, 313, 18, 2673, 11, 17, 15, 27706, 34, 5620, 292, 13385, 18927, 25331, 2886, 11, 1047, 313, 21, 2673, 1630, 313, 24, 2673, 17, 15, 2313, 313, 17, 2673, 19, 313, 18, 2673, 17, 15, 2417, 3233, 403, 3559, 347, 1180, 11767, 390, 1599, 313, 3871, 2888, 27004, 37, 11, 28289, 37534, 12698, 2728, 13, 475, 3338, 4576, 11, 36380, 24664, 14, 19579, 475, 998, 38428, 329, 21993, 2992, 475, 6784, 4576, 11, 36380, 24664, 14, 18305, 475, 998, 38428, 329, 21993, 13, 34520, 52, 11, 3759, 446, 1245, 7928, 32337, 4868, 13, 475, 8683, 5377, 11, 18374, 1624, 1963, 4433, 6803, 13, 475, 55, 2088, 11, 23780, 300, 1080, 14, 12534, 18277, 13, 475, 55, 1194, 11, 23780, 300, 1080, 14, 12534, 32122, 706, 1406, 348, 5895, 11 ]
8} The primary aim of this study was to evaluate the accuracy of the CPIS to differentiate VAT from VAP in patients with microbiologically confirmed VA-LRTI. Statistical analysis {#Sec9} -------------------- Categorical variables were expressed as numbers (percentages) and compared using Chi square test or Fisher's exact test, as appropriate. Normality of distribution of continuous variables was checked graphically and using the Shapiro--Wilk test. Skewed continuous variables were presented as medians (interquartile ranges), and compared using Mann--Whitney *U* tests. Normally distributed continuous variables were presented as means (SD), and compared using Student's *t* tests. Correlations between skewed continuous variables were assessed using Spearman's rank correlation tests, and regression lines were displayed using simple linear regression method. To assess the diagnostic ability of CPIS to differentiate VAT from VAP, we performed a Receiver Operating Characteristics (ROC) analysis for the diagnosis of VAP in both derivation and validation cohorts. We computed the area under the ROC curve (AUC) and the sensitivity, specificity, positive and negative predictive values (PPV and NPV) as well as positive and negative likelihood ratios for different cut-off values. The best cut-off for the discrimination between VAP and VAT was determined according to the Youden index. All statistical tests were two-tailed and *p* values \< 0.05 were considered statistically significant. Statistics Department of Lille University Hospital performed all data analyses using SAS software package, release 9.4 (SAS Institute, Cary, NC, USA). Results {#Sec10} ======= Three hundred twenty patients with VAT and 369 patients with VAP were included in the derivation cohort. Seventy patients with VAT and 136 patients with VAP were included in the validation cohort. Percentage of male and percentage of cirrhosis were higher, whilst age was lower in patients with VAP compared to patients with VAT in the derivation cohort. SOFA score was higher and percentage of heart failure was lower in patients with VAP compared to patients with VAT in the validation cohort. Appropriate initial antimicrobial therapy was more frequent in VAP than in VAT in the derivation cohort, and less frequent in VAP compared to VAT in the validation cohort (Table [1](#Tab1){ref-type="table"}). Comparisons of baseline patients characteristics between derivation and validation cohorts are shown in Additional file [2](#MOESM2){ref-type="media"}. Table 1Baseline characteristics of patientsDerivation cohortP valueValidation cohort*P* valueVAT (*n* = 320)VAP (*n* = 369)VAT (*n* = 70)VAP (*n* = 136)Sex Male199 (62%)264 (72%)51 (73%)102 (75%) Female121 (38%)105 (28%)*0.009*19 (27%)34 (25%)0.74Age (years)61.20 (16.25)57.74 (18.46)*0.009*55.26 (16.1)54.98 (16.36)0.89SAPS II48.85 (18.12)49.89 (17.80)0.4554.6 (19.46)59.97 (16.68)0.079SOFA7.64 (3.79)8.07 (3.63)0.137.19 (4.34)8.9 (4.04)*0.008*Admission category Medical175 (55%)218 (59%)57 (81%)117 (86%) Surgical145 (45%)151 (41%)0.2513 (19%)19 (14%)0.39 COPD64 (20%)61 (17%)0.246 (10%)21 (15%)0.17 Diabetes mellitus66 (21%)69 (19%)0.5314 (20%)26 (20%)0.88 Immunocompromised patients24 (8%)31 (8%)0.667 (10%)23 (17%)0.18 Chronic heart failure27 (8%)19 (5%)0.08516 (23%)16 (12%)*0.037* Chronic respiratory failure35 (11%)27 (7%)0.0983 (4%)7 (5%)0.78 Cirrhosis8 (2%)23 (6%)*0.018*3 (4%)10 (7%)0.38 Previous antibiotic use210 (66%)232 (63%)0.4560 (86%)107 (79%)0.3 Appropriate initial antimicrobial therapy174 (54%)257 (70%)\< 0.00140 (57%)55 (40%)0.023Data are presented as number (%) or mean (SD)*COPD* Chronic obstructive pulmonary disease, *SAPS* Simplified acute physiology score, *SOFA* Sequential organ failure assessment, *VAP* Ventilator-associated pneumonia, *VAT* Ventilator-associated tracheobronchitis*p* value \< 0.05 is indicated in italic characters Clinical outcomes in the derivation and validation cohorts are shown in Table [2](#Tab2){ref-type="table"} and Additional file [3](#MOESM3){ref-type="media"}. ICU mortality was higher in patients with VAP compared to patients with VAT in the derivation cohort.Table 2Clinical outcomes of patientsDerivation cohort*P* valueValidation cohort*P* valueVAT (*n* = 320)VAP (*n* = 369)VAT (*n* = 70)VAP (*n* = 136)Days on mechanical ventilation13 (8--20)13 (8--26)0.3518 (13--29)17 (11--29)0.23Days in the ICU21 (15--34)22 (13--36)0.6924 (16 -- 37)22 (14--35)0.3ICU mortality93 (29%)146 (40%)*0.004*18 (26%)46 (34%)0.23Progression from VAT to VAP39 (12%)--**--**7 (10%)----Data are presented as number (%) or median (interquartile range)*ICU* Intensive Care Unit; *VAP* Ventilator-Associated Pneumonia; *VAT* Ventilator-Associated Tracheobronchitis*p* values \< 0.05 are indicated in italics characters The analysis of microbiological findings revealed a higher frequency of *Enterobacter* spp. in patients with VAP compared to patients with VAT in the validation cohort. Conversely, *Citrobacter freundii* was found more frequently in VATs than in VAPs in the validation cohort (Table [3](#Tab3){ref-type="table"}). Comparisons of microbiological findings between derivation and validation cohorts are shown in Additional file [4](#MOESM4){ref-type="media"}. CPIS values ranged from 0 to 10 for patients with VAT and from 0 to 11 for patients with VAP in the derivation cohort. In the validation cohort, CPIS values ranged from 2 to 10 for patients with VAT and from 1 to 10 for patients with VAP.Table 3Microbiological findingsDerivation cohortP valueValidation cohort*P* valueVAT (*n* = 320)VAP (*n* = 369)VAT (*n* = 70)VAP (*n* = 136)*Streptococcus pneumoniae*16 (5%)24 (7%)0.412 (3%)5 (4%)1*Stenotrophomonas maltophila*19 (6%)12 (3%)0.094 (6%)6 (4%)0.74MRSA8 (2%)8 (2%)0.771 (1%)1 (1%)1MSSA66 (21%)80 (22%)0.736 (9%)21 (15%)0.17*Serratia marcescens*12 (4%)16 (4%)0.693 (4%)5 (4%)1*Pseudomonas aeruginosa*79 (25%)89 (24%)0.8620 (29%)29 (21%)0.25*Proteus mirabilis*15 (5%)14 (4%)0.563 (4%)5 (4%)1*Klebsiella pneumoniae*48 (15%)53 (14%)0.819 (13%)30 (22%)0.11*Haemophilus influenzae*32 (10%)25 (7%)0.124 (6%)6 (4%)0.74*Escherichia coli*37 (12%)40 (11%)0.765 (7%)9 (7%)1*Enterobacter* spp.35 (11%)46 (12%)0.534 (6%)21 (15%)*0.043Citrobacter freundii*7 (2%)6 (2%)0.584 (6%)1 (1%)*0.047Acinetobacter baumannii*14 (4%)27 (7%)0.100 (0%)2 (1%)0.55Data are presented as number (%) or mean (SD)*COPD* Chronic obstructive pulmonary disease, *MSSA* Methicillin-sensitive *Staphylococcus Aureus*, *MRSA* Methicillin-resistant *Staphylococcus Aureus, SAPS* Simplified acute physiology score, *SOFA* Sequential organ failure assessment, *VAP* Ventilator-associated pneumonia, *VAT* Ventilator-associated tracheobronchitis*
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Ryan has worked at Yark Automotive for 12 years. He is married and has two sons that are 4 and 8. Outside of work, he enjoys golfing and playing with his kids. Ryan says that he cannot live without food and water, of course, but he also cannot live without his family. His favorite place to be is anywhere with a beach. The weirdest job he has ever had was doing landscaping for a graveyard. Ryan's favorite car is a Jeep Wrangler. Jake has been with Yark Automotive Group for 5 years. He has two brothers (one works at Yark), and he recently got engaged. He has a boxer and a boxer hound pit bull mix, and their names are Dallas and Cali. Outside of work, Jake enjoys golfing, hanging out with family, going to sporting events, snowboarding, and anything sports related. One thing he cannot live without is quality time with his pups. His favorite place to be is anywhere where there is a sandy beach, most recently Cabo. The weirdest job Jake has ever had was working at a driving range and batting cage where he had to drive around and pick up golf balls. He says people would always try to tee off at him! Jake's favorite car is his car, a 2017 BMW 540. Scott has worked at Yark since November of 2003. He is married and has a 13 year old step daughter and twins that were born in February. Outside of work, Scott plays a lot of golf. One thing he cannot live without is vacation and having time away to relax. His favorite places to be are St. Pete Beach and Hawaii. The weirdest job he has ever had is working at Chuck E. Cheese when he was 17. Scott's favorite car is a Tesla. Dave (otherwise known as "The Guy in Camo") has worked at Yark for 6 years. He has a 14 year old son, Caleb, an 8 year old daughter, Ellianna, and a 3 year old daughter, Atleigh. He has been married to his wife, Emily, for 9 years. He has 2 dogs, Harry Potter and Dobby, and a cat named Bella Swan (from Twilight). He doesn't have a say in the pets' names. He also has 30 quail, 13 ducks, and 2 geese. He spends a lot of time hunting, fishing, farming, watching movies, and raising his ducks and quail. The one thing Dave cannot live without is TV. His favorite place to be is in the woods, of course. The weirdest job he has ever had is being an ostrich farmer. His favorite car is a green 1968 Chevelle 396 with a racing stripe. Corey has worked at Yark Automotive for 6 years. He has 3 kids, 2 girls and a boy. His oldest daughter is a sophomore at Baylor, and his younger 2 kids are extremely active in sports and extra-curriculars. Outside of work, Corey enjoys golfing, cooking, and chasing his kids around. The one thing he cannot live without is his kids. Corey's favorite place to be is Montreal. The weirdest job he has ever had was working as a Mortgage Banker in Easter Market. His favorite car is the first car he had, an '88 Cadillac which he named Clyde. Dave has worked at Yark Automotive for 19 years. He and his wife, Julia, have two kids, Jacob and Lexi. His favorite things to do outside of work are reading, scouts, watching movies, spending time with his family, and going to church. One thing that he can't live without is his family, of course. If Dave could be anywhere, he would be somewhere warm or on a high-adventure trip. The weirdest job he has ever had was working at a cemetery. His favorite car is a 1965 Chevy Corvette convertible. Sean has worked at Yark Automotive since October of 2016. He has one son named Grant who lives with him, and he is three years old. Outside of work, his favorite things to do are spending time with his son and going golfing. One thing Sean cannot live without is his family. His favorite place to be is anywhere on the water. The weirdest job he has ever had is spraying pesticides into trees for a landscaping company. Sean's favorite car is a 1967 SS Chevy Impala. Jerry has worked at Yark Automotive for 11 years. He has 5 siblings and has been married for 23 years. He and his wife recently adopted a dog; they think she is a lab/shepherd mix, and her name is Stella. Outside of work, Jerry enjoys hiking trips, scuba diving and jet skiing, and has recently taken up golf again after a decade. He also enjoys music. His favorite place to be is anywhere near the ocean. The weirdest job Jerry has ever had is counting magazines at Buckeye News during the summer before he went to college. His favorite car is a '65 Mustang. Brandon has worked at Yark for 4 years. He is married and has 3 young boys and 2 pit bulls. Outside of work, his favorite things to do are working out, swimming, and sleeping. Brandon says that he can't live without his phone because he likes being connected. If he could be anywhere, he would be somewhere warm, and his favorite place to travel to is Jamaica. The weirdest job he ever had was being a lifeguard. His favorite car is a Hellcat. Brett has worked at Yark Automotive for 6 years. He is the youngest in his family and has 3 siblings. His dad also works at Yark! Brett says his family loves animals and they have a couple dogs and a cat. They are also huge Ohio State fans and enjoy going to football games. Outside of work, Brett enjoys hanging out with his friends, boating, trying new restaurants, and traveling to new places. He says he cannot live without the relationships he has with his family and friends. His favorite place to be is on a beach somewhere, relaxing and not doing anything. Brett says that he hasn't really had any weird jobs. He says he has only ever worked at Yark and has had many positions, some more desirable than others like painting buildings, but is appreciative of his experiences. Brett's favorite car is a 2016 McLaren P1. Steve has worked at Yark for 3 and a half years. He is from Ottawa Lake, Michigan and lives in Toledo now, and most of his family lives close by. Steve has 3 sisters, a brother that passed away, and parents that have been married 57 years. He has a girlfriend, Hannah, of 1 year. Outside of work, he enjoys golfing and traveling to Vegas or any golf destination. One thing he cannot live without is steak and seafood. Steve's favorite place to be is the first tee of any golf course, but his favorite is Arcadia Bluffs. The weirdest job he has ever had is working for Midwest Products. Steve's favorite car is a BMW 5 series. Ernie has worked at Yark Automotive for a year and a half. He has 4 brothers, one of which also works at Yark, and 1 sister. He and his wife are expecting their first child within the next few days. Ernie says he is very close with his family. Outside of work, Ernie enjoys going to sporting events and traveling. One thing he cannot live without is his family which is the reason he says he has not moved out west. His favorite place to be is at his home in Mexico. The weirdest job he has ever had is doing outside sales, and he says that on the first day he was robbed and the company car was stolen in Detroit. Ernie's favorite car is his truck or a Mercedes G-Wagon. Lynn has been with Yark Automotive Group for 15 years. She's married and has a very large family. She has 5 kids and 17 grandkids, and babysitting her grandkids is her favorite thing to do outside of work. One thing Lynn can't live without is her family. Her favorite place to be is at home or on the beach. She says the weirdest job she's ever had is working at a car dealership, and her favorite car is a sky blue Oldsmobile Cutlass Supreme 442. Desiree has worked at Yark for almost 4 years. She is very close with her family, especially her mom. Desiree spends a lot of time relaxing and watching Netflix when she isn't working; her favorite place to be is in her bed watching Netflix. One thing she cannot live without is chapstick. The weirdest job she has ever had is working in sales because every day is different. Desiree's favorite car is a Jeep Wrangler Brian has worked at Yark Automotive for almost 10 years. He has 9 siblings, 7 sisters and 2 brothers, and was raised by his awesome grandparents. He is married and has a 10 year old son, Cameron, that he calls "Champ". Outside of work, Brian enjoys working in
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Sunday.#ubuntu-ops 2007-06-04 <mc44> _______________________ <mc44> < file bugz plz ompaulz > <mc44> ----------------------- <mc44> \ ,__, <mc44> \ (oo)____ <mc44> (__) )\ <mc44> ||--|| * <rob> oh geez <poningru> WOW <ompaul> cowsay: Could not find bud.frogs cowfile! <Pumpernickel> What have you guys been smoking? * ompaul kills cowsay <ompaul> ______________________________________ <ompaul> / mc44, and where should I file them - \ <ompaul> | dear mc44 - dear mc44 - and where | <ompaul> \ should I file them dear mc44 / <ompaul> -------------------------------------- <ompaul> \ <ompaul> \ <ompaul> oO)-. .-(Oo <ompaul> /__ _\ /_ __\ <ompaul> \ \( | ()~() | )/ / <ompaul> \__|\ | (-___-) | /|__/ <ompaul> ' '--' ==`-'== '--' ' <ompaul> Pumpernickel, /usr/share/cowsay/cows/ is what we are smoking <ompaul> it ain't all safe for work <tonyyarusso> (#ubuntu-cowspam exists if anyone gets upset btw) <ompaul> tonyyarusso, hmm we need to auto join and have a bot there that says new one and reports that info here <tonyyarusso> ompaul: might be arrangable <tonyyarusso> ompaul: If you use \' it works <nalioth> yes, ompaul think of the \ <nalioth> or the " <ompaul> hmm tere are those <ompaul> there are those even <ompaul> I accept this pebkac award for and on behalf of me and some other random command line abusers everywhere * mode/#ubuntu-ops [-b %*!*@pool-71-183-226-118.nycmny.fios.verizon.net] by nalioth <ubotu> rogue780|mythsrv called the ops in #ubuntu-mythtv <poningru>!info snd_usb_audio <ubotu> Package snd_usb_audio does not exist in feisty, feisty-seveas <poningru>!snd_usb_audio <ubotu> Sorry, I don't know anything about snd_usb_audio - try searching on http://bots.ubuntulinux.nl/factoids.cgi <poningru> grr <poningru>!usb audio <ubotu> Sorry, I don't know anything about usb audio - try searching on http://bots.ubuntulinux.nl/factoids.cgi <gnomefreak> @btlogin <nalioth> @lart gnomefreak * ubotu forces gnomefreak to use perl for 3 weeks <gnomefreak> troll gone :) <gnomefreak> someone to come in a complain ill be right back looksing for something atm <brylie> I would like to report op abuse <gnomefreak> im at log level if you need them <gnomefreak> looking for something else <nalioth> brylie: what's up? <brylie> gnomefreak may be helping certain people. he muted me and I believe undeservedly. <gnomefreak> i muted him after telling him and another user to take the gmail-neta talk to -offtopic <mneptok> brylie: #ubuntu is a support channel. if you're asked to take offtopic conversation elsewhere, do so. and if you refuse, being muted may well be the result. that seems fair. <gnomefreak> brylie: gmail beta has nothing to do with ubuntu or ubuntu support * mode/#ubuntu-ops [+v DBO] by ChanServ <brylie> yos, however beta does. <brylie> http://paste.ubuntu-nl.org/23994/ <gnomefreak> brylie: he wasnt talking about beta he was talking about gmail beta <brylie> I had answered his question about how to bug report for gmail <gnomefreak> brylie: we dont support bugs for gmail <brylie> and was seeking to clarify the definition of beta itself [gmail aside] <mneptok> brylie: regardless of GMail, you were asked to stop and you didn't. <brylie> I did so stop <mneptok> that's the only relevant point <brylie> There was no further discussion of Gmail beta <gnomefreak> brylie: no you didnt. after i asked you to stop you posted beta is not offtopic <gnomefreak> that is not stopping <mneptok> OK, then that's the point you want to make. that you followed a request and were muted anyway. * mneptok goes to get food <brylie> because it isn't. > 50% of the software people are requesting support in in #ubuntu is 'beta' <gnomefreak> brylie: if you read before answering him you would have known what was going on. it was about gmail he asked is gmail still beta <brylie> yes. and am mildly frustrated mneptok <gnomefreak> brylie: if you both were talking about beta version of ubuntu you would have been muted as well if you didnt stop when asked to <brylie> gnomefreak, http://paste.ubuntu-nl.org/23994/ <gnomefreak> brylie: i have the logs ty <brylie> and that is what I believe is op abuse <brylie>'stop when asked to' because you have the op commands <gnomefreak> brylie: you were offtopic i asked you to stop. <brylie> I don't believe so clearly off topic as to warrent action <gnomefreak> nalioth: care to be in middle <brylie> and one is also entitled a rebuttle when accused <gnomefreak> how many times should i have asked you to stop? <gnomefreak> 1 or 30 times would it have changed? <brylie> you accepted my rebuttle as you were typing /mute brylie 10minutes or whatever <brylie> yes because the conversation had somewhat ceased when you initally intervened <nalioth> brylie: #ubuntu is for Ubuntu support. Other softwares have their own discussion channels <gnomefreak> brylie: no i didnt. i said stop now you continued than got muted <brylie> you could have, perhaps, suggested we 'take it private? <brylie> thx nalioth <gnomefreak> brylie: i suggest you to take it to #ubuntu-offtopic <brylie> no.. you are distorting context gnomefreak <brylie> http://paste.ubuntu-nl.org/23994/ <nalioth> brylie: i've looked at your pastebin <brylie> sorry to bother y'all with this stuff.. I did my 10 minutes and should be greatful not to be banned. <gnomefreak> 19:37 < gnomefreak > skel: it was released and made public. please ask offtopic questions in #ubuntu-offtopic <nalioth> #ubuntu-offtopic is for discussion of everthing-other-than-ubuntu <brylie>'skel" <gnomefreak> brylie: than he stated about the bugs than you got into it <brylie> not 'brylie' <gnomefreak> brylie: you were watching at that point because within a minute or 2 you got involved and i asked you to stop and you didnt <brylie> maybe just suggest people go 'private' next time is all <gnomefreak> look up a little further from your logs <brylie> I was in the middle of trying not to burn my soy chickenstrips while help ubuntu users <PriceChild> brylie, I think it was made quite clear to you the reason for the first mute, and so you should have noticed the ubotu message to take things to -offtopic. <brylie> <gnomefreak> brylie: i muted him for being offtopic please stay on topic <brylie> <brylie> mainly says that beta is early release.. gnomefreak most of the software people are asking for support on it #ubuntu is beta.. I don't agree that 'beta'
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monster:<player>:0x92:0x81 ?:[AND [EQU $CLASS Warrior] [EQU $RACE Elf] ] monster:<player>:0x92:0x82 ?:[AND [EQU $CLASS Warrior] [EQU $RACE Hobbit] ] monster:<player>:0x92:0x83 ?:[AND [EQU $CLASS Warrior] [EQU $RACE Gnome] ] monster:<player>:0x92:0x84 ?:[AND [EQU $CLASS Warrior] [EQU $RACE Dwarf] ] monster:<player>:0x92:0x85 ?:[AND [EQU $CLASS Warrior] [EQU $RACE Half-Orc] ] monster:<player>:0x92:0x86 ?:[AND [EQU $CLASS Warrior] [EQU $RACE Half-Troll] ] monster:<player>:0x92:0x87 ?:[AND [EQU $CLASS Warrior] [EQU $RACE Dunadan] ] monster:<player>:0x92:0x88 ?:[AND [EQU $CLASS Warrior] [EQU $RACE High-Elf] ] monster:<player>:0x92:0x89 ?:[AND [EQU $CLASS Warrior] [EQU $RACE Kobold] ] monster:<player>:0x92:0x92 ?:[AND [EQU $CLASS Mage] [EQU $RACE Human] ] monster:<player>:0x93:0x80 ?:[AND [EQU $CLASS Mage] [EQU $RACE Half-Elf] ] monster:<player>:0x93:0x81 ?:[AND [EQU $CLASS Mage] [EQU $RACE Elf] ] monster:<player>:0x93:0x82 ?:[AND [EQU $CLASS Mage] [EQU $RACE Hobbit] ] monster:<player>:0x93:0x83 ?:[AND [EQU $CLASS Mage] [EQU $RACE Gnome] ] monster:<player>:0x93:0x84 ?:[AND [EQU $CLASS Mage] [EQU $RACE Dwarf] ] monster:<player>:0x93:0x85 ?:[AND [EQU $CLASS Mage] [EQU $RACE Half-Orc] ] monster:<player>:0x93:0x86 ?:[AND [EQU $CLASS Mage] [EQU $RACE Half-Troll] ] monster:<player>:0x93:0x87 ?:[AND [EQU $CLASS Mage] [EQU $RACE Dunadan] ] monster:<player>:0x93:0x88 ?:[AND [EQU $CLASS Mage] [EQU $RACE High-Elf] ] monster:<player>:0x93:0x89 ?:[AND [EQU $CLASS Mage] [EQU $RACE Kobold] ] monster:<player>:0x93:0x92 ?:[AND [EQU $CLASS Priest] [EQU $RACE Human] ] monster:<player>:0x94:0x80 ?:[AND [EQU $CLASS Priest] [EQU $RACE Half-Elf] ] monster:<player>:0x94:0x81 ?:[AND [EQU $CLASS Priest] [EQU $RACE Elf] ] monster:<player>:0x94:0x82 ?:[AND [EQU $CLASS Priest] [EQU $RACE Hobbit] ] monster:<player>:0x94:0x83 ?:[AND [EQU $CLASS Priest] [EQU $RACE Gnome] ] monster:<player>:0x94:0x84 ?:[AND [EQU $CLASS Priest] [EQU $RACE Dwarf] ] monster:<player>:0x94:0x85 ?:[AND [EQU $CLASS Priest] [EQU $RACE Half-Orc] ] monster:<player>:0x94:0x86 ?:[AND [EQU $CLASS Priest] [EQU $RACE Half-Troll] ] monster:<player>:0x94:0x87 ?:[AND [EQU $CLASS Priest] [EQU $RACE Dunadan] ] monster:<player>:0x94:0x88 ?:[AND [EQU $CLASS Priest] [EQU $RACE High-Elf] ] monster:<player>:0x94:0x89 ?:[AND [EQU $CLASS Priest] [EQU $RACE Kobold] ] monster:<player>:0x94:0x92 ?:[AND [EQU $CLASS Rogue] [EQU $RACE Human] ] monster:<player>:0x95:0x80 ?:[AND [EQU $CLASS Rogue] [EQU $RACE Half-Elf] ] monster:<player>:0x95:0x81 ?:[AND [EQU $CLASS Rogue] [EQU $RACE Elf] ] monster:<player>:0x95:0x82 ?:[AND [EQU $CLASS Rogue] [EQU $RACE Hobbit] ] monster:<player>:0x95:0x83 ?:[AND [EQU $CLASS Rogue] [EQU $RACE Gnome] ] monster:<player>:0x95:0x84 ?:[AND [EQU $CLASS Rogue] [EQU $RACE Dwarf] ] monster:<player>:0x95:0x85 ?:[AND [EQU $CLASS Rogue] [EQU $RACE Half-Orc] ] monster:<player>:0x95:0x86 ?:[AND [EQU $CLASS Rogue] [EQU $RACE Half-Troll] ] monster:<player>:0x95:0x87 ?:[AND [EQU $CLASS Rogue] [EQU $RACE Dunadan] ] monster:<player>:0x95:0x88 ?:[AND [EQU $CLASS Rogue] [EQU $RACE High-Elf] ] monster:<player>:0x95:0x89 ?:[AND [EQU $CLASS Rogue] [EQU $RACE Kobold] ] monster:<player>:0x95:0x92 ?:[AND [EQU $CLASS Ranger] [EQU $RACE Human] ] monster:<player>:0x96:0x80 ?:[AND [EQU $CLASS Ranger] [EQU $RACE Half-Elf] ] monster:<player>:0x96:0x81 ?:[AND [EQU $CLASS Ranger] [EQU $RACE Elf] ] monster:<player>:0x96:0x82 ?:[AND [EQU $CLASS Ranger] [EQU $RACE Hobbit] ] monster:<player>:0x96:0x83 ?:[AND [EQU $CLASS Ranger] [EQU $RACE Gnome] ] monster:<player>:0x96:0x84 ?:[AND [EQU $CLASS Ranger] [EQU $RACE Dwarf] ] monster:<player>:0x96:0x85 ?:[AND [EQU $CLASS Ranger] [EQU $RACE Half-Orc] ] monster:<player>:0x96:0x86 ?:[AND [EQU $CLASS Ranger] [EQU $RACE Half-Troll] ] monster:<player>:0x96:0x87 ?:[AND [EQU $CLASS Ranger] [EQU $RACE Dunadan] ] monster:<player>:0x96:0x88 ?:[AND [EQU $CLASS Ranger] [EQU $RACE High-Elf] ] monster:<player>:0x96:0x89 ?:[AND [EQU $CLASS Ranger] [EQU $RACE Kobold] ] monster:<player>:0x96:0x92 ?:[AND [EQU $CLASS Paladin] [EQU $RACE Human] ] monster:<player>:0x97:0x80 ?:[AND [EQU $CLASS Paladin] [EQU $RACE Half-Elf] ] monster:<player>:0x97:0x81 ?:[AND [EQU $CLASS Paladin] [EQU $RACE Elf] ] monster:<player>:0x97:0x82 ?:[AND [EQU $CLASS Paladin] [EQU $RACE Hobbit]
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this.s=(a<0)?-1:0;if(a>0){this[0]=a}else{if(a<-1){this[0]=a+this.DV}else{this.t=0}}}function nbv(a){var b=nbi();b.fromInt(a);return b}function bnpFromString(h,c){var e;if(c==16){e=4}else{if(c==8){e=3}else{if(c==256){e=8}else{if(c==2){e=1}else{if(c==32){e=5}else{if(c==4){e=2}else{this.fromRadix(h,c);return}}}}}}this.t=0;this.s=0;var g=h.length,d=false,f=0;while(--g>=0){var a=(e==8)?h[g]&255:intAt(h,g);if(a<0){if(h.charAt(g)=="-"){d=true}continue}d=false;if(f==0){this[this.t++]=a}else{if(f+e>this.DB){this[this.t-1]|=(a&((1<<(this.DB-f))-1))<<f;this[this.t++]=(a>>(this.DB-f))}else{this[this.t-1]|=a<<f}}f+=e;if(f>=this.DB){f-=this.DB}}if(e==8&&(h[0]&128)!=0){this.s=-1;if(f>0){this[this.t-1]|=((1<<(this.DB-f))-1)<<f}}this.clamp();if(d){BigInteger.ZERO.subTo(this,this)}}function bnpClamp(){var a=this.s&this.DM;while(this.t>0&&this[this.t-1]==a){--this.t}}function bnToString(c){if(this.s<0){return"-"+this.negate().toString(c)}var e;if(c==16){e=4}else{if(c==8){e=3}else{if(c==2){e=1}else{if(c==32){e=5}else{if(c==4){e=2}else{return this.toRadix(c)}}}}}var g=(1<<e)-1,l,a=false,h="",f=this.t;var j=this.DB-(f*this.DB)%e;if(f-->0){if(j<this.DB&&(l=this[f]>>j)>0){a=true;h=int2char(l)}while(f>=0){if(j<e){l=(this[f]&((1<<j)-1))<<(e-j);l|=this[--f]>>(j+=this.DB-e)}else{l=(this[f]>>(j-=e))&g;if(j<=0){j+=this.DB;--f}}if(l>0){a=true}if(a){h+=int2char(l)}}}return a?h:"0"}function bnNegate(){var a=nbi();BigInteger.ZERO.subTo(this,a);return a}function bnAbs(){return(this.s<0)?this.negate():this}function bnCompareTo(b){var d=this.s-b.s;if(d!=0){return d}var c=this.t;d=c-b.t;if(d!=0){return(this.s<0)?-d:d}while(--c>=0){if((d=this[c]-b[c])!=0){return d}}return 0}function nbits(a){var c=1,b;if((b=a>>>16)!=0){a=b;c+=16}if((b=a>>8)!=0){a=b;c+=8}if((b=a>>4)!=0){a=b;c+=4}if((b=a>>2)!=0){a=b;c+=2}if((b=a>>1)!=0){a=b;c+=1}return c}function bnBitLength(){if(this.t<=0){return 0}return this.DB*(this.t-1)+nbits(this[this.t-1]^(this.s&this.DM))}function bnpDLShiftTo(c,b){var a;for(a=this.t-1;a>=0;--a){b[a+c]=this[a]}for(a=c-1;a>=0;--a){b[a]=0}b.t=this.t+c;b.s=this.s}function bnpDRShiftTo(c,b){for(var a=c;a<this.t;++a){b[a-c]=this[a]}b.t=Math.max(this.t-c,0);b.s=this.s}function bnpLShiftTo(j,e){var b=j%this.DB;var a=this.DB-b;var g=(1<<a)-1;var f=Math.floor(j/this.DB),h=(this.s<<b)&this.DM,d;for(d=this.t-1;d>=0;--d){e[d+f+1]=(this[d]>>a)|h;h=(this[d]&g)<<b}for(d=f-1;d>=0;--d){e[d]=0}e[f]=h;e.t=this.t+f+1;e.s=this.s;e.clamp()}function bnpRShiftTo(g,d){d.s=this.s;var e=Math.floor(g/this.DB);if(e>=this.t){d.t=0;return}var b=g%this.DB;var a=this.DB-b;var f=(1<<b)-1;d[0]=this[e]>>b;for(var c=e+1;c<this.t;++c){d[c-e-1]|=(this[c]&f)<<a;d[c-e]=this[c]>>b}if(b>0){d[this.t-e-1]|=(this.s&f)<<a}d.t=this.t-e;d.clamp()}function bnpSubTo(d,f){var e=0,g=0,b=Math.min(d.t,this.t);while(e<b){g+=this[e]-d[e];f[e++]=g&this.DM;g>>=this.DB}if(d.t<this.t){g-=d.s;while(e<this.t){g+=this[e];f[e++]=g&this.DM;g>>=this.DB}g+=this.s}else{g+=this.s;while(e<d.t){g-=d[e];f[e++]=g&this.DM;g>>=this.DB}g-=d.s}f.s=(g<0)?-1:0;if(g<-1){f[e++]=this.DV+g}else{if(g>0){f[e++]=g}}f.t=e;f.clamp()}function bnpMultiplyTo(c,e){var b=this.abs(),f=c.abs();var d=b.t;e.t=d+f.t;while(--d>=0){e[d]=0}for(d=0;d<f.t;++d){e[d+b.t]=b.am(0,f[d],e,d,0,b.t)}e.s=0;e.clamp();if(this.s!=c.s){BigInteger.ZERO.subTo(e,e)}}function bnpSquareTo(d){var a=this.abs();var b=d.t=2*a.t;while(--b>=0){d[b]=0}for(b=0;b<a.t-1;++b){var e=a.am(b,a[b],d,2*b,0,1);if((d[b+a.t]+=a.am(b+1,2*a[b],d,2*b+1,e,a.t-b-1))>=a.DV){d[b+a.t]-=a.DV
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! สามีฉันอยู่ข้างล่างคนเดียว ฉันพูดว่าเข้าไปแล้วและเขย่ามือไปมา ไม่มีเรี่ยวแรงจะตะโกนออกมา ฉันมีความสุขมากค่ะ Indonesian: Ia menghadapinya disini, lalu berhenti. Ia bergerak kesana lalu kembali... kemudian ia mencetak gol di clasico. Ia membuat sebuah penyelesaian lewat sebuah tembakan yang menembus gawang. Saya tidak ingat persisnya...Saya berteriak gol! Suami saya sedang di bawah sendirian dan saya berkata gol dan menggerakkan tangan saya, karena saya tidak bisa berteriak. Saya sangat bahagia. Portuguese: Eu usava uma camisa dedicada a ele que sua irmã pediu e depois eu dei a eles. Depois, todo mundo estava falando sobre Kun. Ele é minha referência para o Independiente e eu o amo. Volta para El Rojo! Ele é o número um de El Rojo! Eu estava na esquina do antigo estande da Doble Visera e lembro de assisti-lo daquele lado. Foi magnífico! Ele fez o zagueiro dançar e terminou chutando junto ao poste. Foi um gol notável. É algo que hoje em dia pode assistir em qualquer rede social, Youtube, Facebook... nós temos isso aqui. Foi magnífico como foi, porque alegrou nosso domingo e nós obviamente estávamos felizes porque ganhamos contra nossos ferozes rivais. Todos nós queremos que ele jogue aqui conosco. Spanish: Me puse una remera que era para él, y… la hermana me lo pidió y se lo terminé dando a ella. Descolló y todo el mundo ya hablaba del Kun. Mi referente de Independiente y lo amo, ¡que vuelva al Rojo! El número 1 del Rojo. En el codo estaba yo, del antiguo Doble Visera, me acuerdo verlo desde ese lateral, ¡fue magnífico! Me hizo bailar y definió contra el palo y fue espectacular ese gol. Esa joya que la tenemos hoy en cualquier red social, en Youtube, en Facebook, la tenemos ahí. Majestuoso por cómo fue, porque nos alegró el domingo, y obviamente nos alegró al ganarle al rival de toda la vida. Todos queremos que esté jugando acá con nosotros. Indonesian: Saya mengenakan kaos dedikasi untuknya dan setelahnya kakaknya meminta kaos itu, jadi saya berikan kepadanya. Setelah itu semua orang membicarakan tentang Kun. Ia adalah pedoman saya di Independiente dan saya mencintainya. Kembali ke El Rojo! Dia adalah El Rojo! Nomor satu! Saya berada di pojok tribun Doble Visera yang lama dan saya ingat menontonnya dari sisi itu sungguh hebat! Ia membuat bek menari dan menyelesaikan dengan gol ke pojok gawang, itu adalah gol yang menakjubkan. Itu adalah gol yang dewasa ini bisa Anda tonton di media sosial, Youtube, Facebook... Kami memilikinya disini. Gol itu sungguh menakjubkan, karena itu membuat hari Minggu kami berkesan dan tentunya jelas kami sangat bahagia karena kami mengalahkan rival utama kami. Semua orang menginginkannya bermain disini bersama kami. French: Je portais un t-shirt avec un message qui lui était dédié. Sa sœur me l'a demandé et je le lui ai donné après. Après ça, tout le monde parlait de Kun. C’est ma référence pour Independiente, j’adore ce joueur. Reviens chez El Rojo! C’est le numéro 1 d’El Rojo! J’étais dans le coin de l’ancienne tribune Doble Visera et je l’ai vu jouer avec cette équipe. C’était magnifique! Il a fait danser le défenseur et il marque au second poteau. C’était un but incroyable. Vous pouvez voir ce but sur tous les réseaux sociaux aujourd’hui, sur YouTube, Facebook... Il y est. Il est magnifique, d’autant que c’était notre dimanche, et que bien sûr on était super contents de battre notre grand rival. On voulait tous qu’il joue dans notre équipe! Chinese: 我為他穿了一件衣服 之後他姐姐問我要，我就給了她 自此之後，阿Kun無人不曉 他是我的獨立隊標誌，我愛他，回來吧! 他是獨立隊的一號人物! 我當時在Doble Visera看台 還記得從旁邊看他 他令敵衛左跳右跳，然後拉遠柱一射中網 極漂亮的一球! 今時今日你可以隨時在社交網站重溫這個入球 Youtube、Facebook，都有 當時看真的精彩絕倫，燃亮了我一整天 力挫宿敵，大家都樂不可支 大家都想他在這裡作賽 他對我們來說很重要 Russian: На мне была футболка в честь Эмилиано, - сестра потом попросила её, я отдал её семье. После матча все говорили о Куне. Для меня он является символом «Индепендьенте», я обожаю Агуэро. Возвращайся к нам! Серхио – лучший игрок El Rojo! Моё место было в углу трибуны Добле Висера, и я помню, как оттуда следил за игрой. Невероятный матч! Защитнику пришлось плясать вокруг него, а в результате Серхио забил потрясающий гол. В наши дни такие моменты можно пересматривать в соцсетях – Ютьюбе, Фейсбуке… В то воскресенье мы были рады обыграть старого противника. Мы все хотим, чтобы он продолжал играть здесь. Arabic: ارتديت قميصا مخصصا له وبعد ذلك طلبته شقيقته وأعطيته لها بعد ذلك، كان الجميع يتحدثون عن الكون إنه رمز بال
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to 10 (herein, pAg value is a reciprocal of Ag+ ion concentration). As a water soluble silver salt, silver nitrate is preferred. By adding the water soluble silver salt, so-called silver ripening is conducted which is one kind of the reduction sensitizing technique. pAg of the silver ripening is suitably 1 to 6, more suitably 2 to 4. As the condition of temperature, pH and time, the above-mentioned reduction sensitization condition is preferred. As a stabilizer of the silver halide photographic emulsion containing the silver halide grains subjected to the reduction sensitization of the invention, later mentioned general stabilizer can be used, but in combined usage with an antioxidant described in JP-A No. 57-82831 and/or thiosulfonic acid derivatives described in V. S. Gahler, [Festschrift fur wissenschaftliche Photographie Bd. 63, 133 (1969)] and JP-A 54-1019, excellent results are often obtained. Addition of these compounds may be conducted in any process of emulsion manufacturing process after crystal growth process until adjusting process just before coating. In the present invention, fine particle silver halide grains can be added during any process after chemical ripening process until coating process, which includes the process between chemical ripening and coating thereafter. For the purpose of accelerating adsorption of a spectral sensitizing dye to the silver halide grains, the fine silver iodide grains may be added during any process from chemical ripening to the period just before coating, but are preferably added during the chemical ripening. The chemical ripening process refers to a process from the time when physical ripening and a salt removal operation of the emulsion of the present invention are completed to the time when an operation is conducted to terminate the chemical ripening. Furthermore, the fine silver iodide grains may be intermittently added several times, and after the addition of the fine silver iodide grains, another chemical-ripened emulsion may be added. When the fine silver iodide grains are added, the temperature of the emulsion in a liquid state is preferably in the range of 30 to 80xc2x0 C. and more preferably in the range of 40 to 65xc2x0 C. The fine silver iodide grains is preferably added in a manner in which part or all of it disappears after addition of it until coating, and it is more preferable that not less than 20% of added fine silver iodide grains disappears just before coating. A bleachable or bleachable dye may be contained in any optional at least one layer constituting a silver halide emulsion containing layer or a layer other than the silver halide emulsion containing layer. In this case, the light-sensitive material with high sensitivity, high sharpness and less dye stain can be obtained. The dye used in the light-sensitive material is appropriately selected from dyes capable of enhancing sharpness to remove undesired influence caused by light wavelength by absorbing the wavelength. It is preferable that the dye bleaches or leaches during developing process and when an image is formed, no stain is visually recognized. The dye may be added in any constituting layer. That is, the dye may be added in at least one layer such as a light-sensitive emulsion layer, or other hydrophilic colloidal layer coated on the same side as said light-sensitive emulsion layer (for example, non-light sensitive layer such as an intermediate layer, a protective layer, a sublayer). The dye is preferably contained in either a silver halide emulsion layer or a layer closer to a support, or contained in both layers, more preferably contained in a layer adjacent to a transparent support. The concentration of the dye is preferably higher in the layer closer to the support. In the present invention, an adding amount of the above-mentioned dye is variable according to an intended object of sharpness, but is preferably 0.2 mg/m2 to 20 mg/m2, more preferably 0.8 mg/m2 to 15 mg/m2. The above-mentioned dye can be incorporated into a hydrophilic colloidal layer in an usual manner, namely, an appropriate concentration of aqueous solution of the dye or a solid fine particle dispersion of the dye can be incorporated. JP-A Nos. 1-158430, 2-115830, 4-251838 can be referred. In cases where the silver halide emulsion layer is dyed, the dye is incorporated into a silver halide emulsion solution prior to coating or into an aqueous solution of hydrophilic colloid, then these solutions may be coated directly or through other hydrophilic colloidal layer on the support in various coating manners. As mentioned above, it is preferred that the concentration of the dye is preferably higher in the layer closer to the support, therefore, in order to fix the dye in the layer closer to the support, a mordant can be applied. For example, nondiffusing mordant which bonds with at least one kind of the aforesaid dyes can be used. The nondiffusing mordant can be bonded with the dye in known various manners in this art, specifically, bonding in gelatin powder is usually employed. Otherwise, after bonding in an appropriate binder, then thus obtained binder is dispersed in aqueous gelatin solution employing an ultrasonic homogenizer. Bonding ratio is not constant depending on compounds, but usually 0.1 to 10 parts of the nondiffusing mordant bonds with 1 part of a water soluble dye. Using amount of the water soluble dye in combination with the nondiffusing mordant can be more than that of the singly used water soluble dye. In cases where the dye bonded with the nondiffusing mordant is contained in the light-sensitive material, a constituting layer containing the dye bonded with the nondiffusing mordant is newly provided, but it is preferable that said layer is a coating layer adjacent to the transparent support. Hydrazine compounds or tetrazolium compounds may be employed as contrast enhancing agent in case that the silver halide emulsion is adopted to a lithographic light sensitive material. Further nucleation accelerating agent can be employed. These are optionally added corresponding to the purpose of the light sensitive materials. A variety of photographic c can be employed in the photographic material relating to the invention. The conventional v include compounds described in Research Disclosure No. 17643 (1978, December), ibid No. 18716 (1979, November), and ibid No. 308119 (1989, December). Below, compounds disclosed in these three references and locations thereof are given. To the silver halide photographic light-sensitive material, if necessary, is applicable an antihalation layer, an intermediate layer, a filter layer, etc. In the photographic light-sensitive material of the present invention, a photographic layer and other hydrophilic colloidal layer can be coated on the support or other layer in various coating manners. Methods of coating include a dip coating method, a roller coating method, a curtain coating method, an extrusion coating method and a slide-hopper coating method, etc. The methods described in Research Disclosure, vol. 176, p. 27 to 28, xe2x80x9cCoating proceduresxe2x80x9d can be usable. In the silver halide photographic light-sensitive material of the present invention, a developing agent such as aminophenol, ascorbic acid, pyrocatechol, hydroquinone, phenylenediamine or 3-pyrazolidone may be contained in the emulsion layer or other layers.{ "cells": [ { "cell_type": "markdown", "metadata": {}, "source": [ "# The End\n", "\n", "![https://twitter.com/karpathy/status/1013244313327681536](img/common_mistakes.png)\n", "https://twitter.com/karpathy/status/1013244313327681536" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "**Goals:**\n", "- understand PyTorch concepts\n", "- be able to use transfer learning in PyTorch\n", "- be aware of some handy tools/libs" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "# Interesting reads\n", "\n", "- [The road to 1.0: production ready PyTorch](https://pytorch.org/2018/05/02/road-to-1.0.html)\n", " - `torch.jit`\n", " - optimize for mobile\n", " - quantized inference (such as 8-bit inference)\n", " - [caffe2 already merged into pytorch repo](https://github.com/pytorch/pytorch/tree/master/caffe2)\n", " - ONNX - Open Neural Network Exchange\n", "\n", "- [PyTorch under the hood](https://speakerdeck.com/perone/pytorch-under-the-hood)\n", "- PyTorch 1.0 videos" ] } ], "metadata": { "kernelspec": { "display_name": "Python 3", "language": "python", "name": "python3" }, "language_info": { "codemirror_mode": { "
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< Transfer-Encoding: chunked < {"stream":"Step 1/4 : FROM ubuntu:14.04\n"} {"stream":" ---\u003e 302fa07d8117\n"} {"stream":"Step 2/4 : RUN mkdir demo\n"} {"stream":" ---\u003e Running in 5941f911099e\n"} {"stream":" ---\u003e bccbffdd776a\n"} {"stream":"Removing intermediate container 5941f911099e\n"} {"stream":"Step 3/4 : RUN apt-get update\n"} {"stream":" ---\u003e Running in 7aefd190a165\n"} {"stream":"Ign http://archive.ubuntu.com trusty InRelease\n"} {"stream":"Get:1 http://archive.ubuntu.com trusty-updates InRelease [65.9 kB]\n"} {"stream":"Get:2 http://archive.ubuntu.com trusty-security InRelease [65.9 kB]\n"} {"stream":"Get:3 http://archive.ubuntu.com trusty Release.gpg [933 B]\n"} {"stream":"Get:4 http://archive.ubuntu.com trusty Release [58.5 kB]\n"} {"stream":"Get:5 http://archive.ubuntu.com trusty-updates/main Sources [491 kB]\n"} {"stream":"Get:6 http://archive.ubuntu.com trusty-updates/restricted Sources [6467 B]\n"} {"stream":"Get:7 http://archive.ubuntu.com trusty-updates/universe Sources [226 kB]\n"} ....... {"stream":"Fetched 22.5 MB in 1min 40s (224 kB/s)\nReading package lists..."} {"stream":"\n"} {"stream":" ---\u003e ff06741dea7e\n"} {"stream":"Removing intermediate container 7aefd190a165\n"} {"stream":"Step 4/4 : RUN apt-get -y install vim\n"} {"stream":" ---\u003e Running in e9ddad5a4695\n"} {"stream":"Reading package lists..."} {"stream":"\n"} {"stream":"Building dependency tree..."} {"stream":"\nReading state information...\n"} {"stream":"The following extra packages will be installed:\n libgpm2 libpython2.7 libpython2.7-minimal libpython2.7-stdlib vim-runtime\n"} {"stream":"Suggested packages:\n gpm ctags vim-doc vim-scripts\n"} {"stream":"The following NEW packages will be installed:\n libgpm2 libpython2.7 libpython2.7-minimal libpython2.7-stdlib vim\n vim-runtime\n"} {"stream":"0 upgraded, 6 newly installed, 0 to remove and 3 not upgraded.\nNeed to get 9074 kB of archives.\nAfter this operation, 42.9 MB of additional disk space will be used.\nGet:1 http://archive.ubuntu.com/ubuntu/ trusty/main libgpm2 amd64 1.20.4-6.1 [16.5 kB]\n"} ....... {"stream":"Processing triggers for libc-bin (2.19-0ubuntu6.11)...\n"} {"stream":" ---\u003e b1736dd9b698\n"} {"stream":"Removing intermediate container e9ddad5a4695\n"} {"stream":"Successfully built b1736dd9b698\n"} * Connection #0 to host 127.0.0.1 left intact Check the docker images after the image is successfully built. # docker images REPOSITORY TAG IMAGE ID CREATED SIZE build_test latest b1736dd9b698 8 seconds ago 254MB Removed some of the output which is not necessary. To configure docker daemon port, refer this Q: Cassandra Cluster Incremental Backup to s3 We've setup a Cassandra cluster with three nodes in a single Available zone(AWS). We're using nodetool snapshot tool to take the backup to S3 storage. Initially, we're planning to take full backup and then enable incremental backup and periodically move the backup to S3. It wouldn't be of great help if anyone could please provide a script which can take incremental backup and move the backups to S3. A: There are tools such as Netflix Priam which can take backups on AWS Please enable javascript to view this site. 100 crore PG admission scam in Andra Pradesh unearthed A probe ordered by governor E S L Narasimhan after President's Rule was imposed in Andhra Pradesh has unearthed a Rs100 crore paper leak scam in the Post-Graduate Medical Entrance Test conducted by the Vijayawada-based Dr NTR University of Health Sciences. The Crime Investigation Department (CID) of Andhra Pradesh Police on Tuesday booked a case in connection with the alleged irregularities in the exam. "The CID has registered a case on charge of cheating and under other relevant sections of IPC and AP Prevention of Malpractices and Unfair Means Act, and has begun its probe," director general of police B Prasada Rao said. The state government had on Monday ordered a CID inquiry into the alleged irregularities in PG Medical Entrance Exam, after a one-man committee, headed by State Council of Higher Education Chairman, L Venugopal Reddy, constituted to look into the issue submitted its report to Governor E S L Narasimhan. A team of CID visited the university and questioned some officials and inquired whether they had any role in the allegations being levelled by aspirants. Around 15,000 students took the examinations held on March 2 for the 2,240-odd seats. Of the total seats, around 1500 belong to government medical colleges. However, hundreds of students had complained that some candidates had secured top ranks though they had failed in some subjects in graduation, besides some others performed poorly in PG entrance exams in other states. The Reddy inquiry committee was set up by the governor following complaints from students that the question papers were leaked and results were rigged, besides other irregularities in the exam process conducted by the NTRUHS. The committee conducted a public hearing at Nagarjuna University, Guntur, and recorded the complaints and allegations of students. It expressed serious doubts about 11 students who secured top ranks in the PG medical entrance exam despite poor performance in the MBBS examination, and in some cases had obtained graduate medical degrees from China and other foreign countries. Andhra Pradesh police suspect a Rs100 crore scam in leaking of the exam papers of the NTR health university which led to failed students of Medicine getting ranks. Each PG seat in private colleges cost as much as Rs one crore, say police investigators. The CID officials who split into ten teams traced the leakage during the processing of the question papers which printed at Bangalore. They have identified 26 persons' involvement by inquiring their whereabouts at Visakhapantam, Guntur,Vijayawada and Hyderabad. "We suspect that about 200 students got the leaked question papers," say the officials. The main suspect Jagadeswar Reddy had managed to procure the pen drive in which the question papers were carried to Bangalore and sold each copy for a massive rate of Rs 50 to 60 lakh, they say adding that cases have been registered under sections 120(b) and 420 on them and arrest warrants are issued on them. However, no arrests have been made so far," said a CID official.Introduction {#Sec1} ============ According to a recent comprehensive review (Lopez [@CR20]: p. 398) the structure of the milk fat globule membrane (MFGM) is "still not known in detail and remains the least understood aspect of the milk fat globule (MFG)". The functional importance of the MFGM lies in its ability to stabilise the lipid droplets in the milk, facilitate the uptake of MFG components by the neonatal gut and to supply the developmental cues provided by the biochemical constituents of the membrane. There is increasing evidence (DeWettinck et al. [@CR9]; Lopez [@CR20]) for the important role of MFGM constituents in the development of the neonatal gut and immune system and in providing antiviral and antimicrobial protection. Longer term, the high glycerolipid content could make an important contribution to nervous system development. The MFGM is also important commercially for its valuable contribution to texture and flavour (DeWettinck et al. [@CR9]), given the widespread use of milk and milk derivatives in the food industry. There are currently two very different interpretations of MFGM structure in the alveolus and in expressed milk. There is a general agreement that, immediately after secretion from the mammary cell into the alveolus, transmission electron microscopyy (TEM) shows that the MFGM is a continuous unit membrane separated from the core lipid by a 15- to 20-nm layer of cytoplasmic origin (Wooding [@CR32], [@CR34]; Mather and Keenan [@CR25]; Vorbach et
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y+p_1(x)+p_2(\alpha_1x)=y+p(x)$. which are again of the form $\phi(x)=\alpha x$ and $\phi(y)=y+p(x)$, implying that an arbitrary composition of automorphisms is of the same form. In order to prove results related to arbitrary automorphisms of $\mathcal{A}(x,y)$, we will need to consider the case when $\phi(x)\in{\mathbb{C}}(x)$. In this case, the possible types of automorphisms can be explicitly described. \[proposition3.4\] Let $\phi:\mathcal{A}(x,y)\rightarrow\mathcal{A}(x,y)$ be a Poisson algebra automorphism such that $\phi(x)\in\mathbb{C}(x)$. Then there exist $\alpha,\beta,\gamma,\delta\in \mathbb{C}$ and $r(x)\in \mathbb{C}(x)$ such that $\alpha\delta-\beta\gamma\neq0$ and $$\begin{aligned} &\phi(x)=\frac{\alpha x+\beta}{\gamma x+\delta}\\ &\phi(y)=\frac{(\alpha x+\beta)(\gamma x+\delta)y}{(\alpha \delta-\beta\gamma)x}+r(x). \end{aligned}$$ If $\phi$ is invertible then, since $\phi(x)\in\mathbb{C}(x)$, $\phi(x)$ has to be an invertible rational function of $x$. It is well known that such a function is of the form $\phi(x)=\frac{\alpha x+\beta}{\gamma x+\delta}$ for some $\alpha,\beta,\gamma,\delta\in \mathbb{C}$ with $\alpha\delta-\beta\gamma\neq0$. Since $\phi$ is a Poisson algebra automorphism, one can determine the possible $\phi(y)$ via $$\begin{aligned} \{\phi(x),\phi(y)\}&=\phi(\{x,y\}). \end{aligned}$$ We start from the left hand side $$\begin{aligned} \{\phi(x),\phi(y)\}&=\Big\{\frac{\alpha x+\beta}{\gamma x+\delta},\phi(y)\Big\}= \Big\{\frac{\alpha x+\beta}{\gamma x+\delta},y\Big\}\phi(y)^\prime_ y= \Big(\frac{\alpha x+\beta}{\gamma x+\delta}\Big)^\prime_x\{x,y\}\phi(y)^\prime_y\\ &=\Big(\frac{\alpha\delta-\beta\gamma}{(\gamma x+\delta)^2}\Big)x\phi(y)^\prime_y, \end{aligned}$$ and from the right hand side we get $$\begin{aligned} \phi(\{x,y\})=\phi(x)=\frac{\alpha x+\beta}{\gamma x+\delta}. \end{aligned}$$ Therefore, we obtain $$\begin{aligned} \frac{\alpha\delta-\beta\gamma}{\gamma x+\delta}x\phi(y)^\prime_y&=\alpha x+\beta{{\quad\Rightarrow\quad}}\\ (\alpha\delta-\beta\gamma)x\phi(y)^\prime_y&=(\alpha x+\beta)(\gamma x+\delta){{\quad\Rightarrow\quad}}\\ \phi(y)&=\frac{(\alpha x+\beta)(\gamma x+\delta)y}{(\alpha \delta-\beta \gamma)x}+r(x). \end{aligned}$$ for some $r(x)\in{\mathbb{C}}(x)$. Let us now start to investigate isomorphism classes of metrics for Kähler-Poisson algebras over $\mathcal{A}(x,y)$. The simplest case is when the metrics are constant; i.e $$\begin{aligned} g=\begin{pmatrix} a & b \\ b & c \\ \end{pmatrix} \qquad\text{and}\qquad \tilde{g}= \begin{pmatrix} \tilde{a} & \tilde{b} \\ \tilde{b} & \tilde{c} \\ \end{pmatrix}\end{aligned}$$ for $a,b,c,\tilde{a},\tilde{b},\tilde{c}\in \mathbb{C}$. \[prop:constant.metric\] Let $\mathcal{K}=(\mathcal{A}(x,y),g,\{x,y\})$ and $\tilde{\mathcal{K}}=(\mathcal{A}(x,y),\tilde{g},\{x,y\})$ be Kähler-Poisson algebras, with $g=\begin{pmatrix} a & b \\ b & c \\ \end{pmatrix}$ and $\tilde{g}=\begin{pmatrix} \tilde{a} & \tilde{b} \\ \tilde{b} & \tilde{c} \\ \end{pmatrix}$ where $a,b,c,\tilde{a},\tilde{b},\tilde{c}\in \mathbb{C}$ such that $\text{det}(g)\neq0$ and $\text{det}(\tilde{g})\neq0$. Then $\mathcal{K}\cong \tilde{\mathcal{K}}$ if and only if $c=\tilde{c}$. First, we assume that $c=\tilde{c}$ and show that $\mathcal{K}\cong \tilde{\mathcal{K}}$ by using an automorphism of the form $\phi(x)=\alpha x$ and $\phi(y)=y+p(x)$ (cf. Lemma \[lemma1\]). We will do this by applying Proposition \[proposition2.2\] to show that there exists $\alpha\in{\mathbb{C}}$ and $p(x)\in{\mathbb{C}}[x]$ such that $$\begin{aligned} \label{eq2} \tilde{g}=A^T\phi(g)A. \end{aligned}$$ First, note that $\phi(g)=g$, since $\phi$ is unital. From $A^i_{\alpha}=\frac{\partial\phi(x^i)}{\partial y^{\alpha}}$ one computes $A=\begin{pmatrix} \frac{\partial\phi(x)}{\partial x} & \frac{\partial\phi(x)}{\partial y} \\ \frac{\partial\phi(y)}{\partial x} & \frac{\partial\phi(y)}{\partial y} \\ \end{pmatrix}=\begin{pmatrix} \alpha & 0 \\ p^{\prime}(x) & 1 \\ \end{pmatrix}$, giving as $$\begin{aligned} \begin{pmatrix} \tilde{a} & \tilde{b} \\ \tilde{b} & c \\ \end{pmatrix}&= \begin{pmatrix} \alpha & p^{\prime}(x) \\ 0 & 1 \\ \end{pmatrix}\begin{pmatrix} a & b \\ b & c \\ \end{pmatrix}\begin{pmatrix} \alpha & 0 \\ p^{\prime}(x) & 1 \\ \end{pmatrix}= \begin{pmatrix} \alpha a+p^{\prime}(x) b & \alpha b+p^{\prime}(x) c \\ b & c \\ \end{pmatrix}\begin{pmatrix} \alpha & 0 \\ p^{\prime}(x) & 1 \\ \end{pmatrix}\\&=\begin{pmatrix} \alpha(\alpha a+p^{\prime}(x) b)+p^{\prime}(x)(\alpha b+p^{\prime}(x) c ) & \alpha b+p^{\prime}(x) c \\ \alpha b+\mathcal{P}^{\prime}(x) c & c \\ \end{pmatrix}, \end{aligned}$$ showing that is equivalent to $$\begin{aligned} \label{eq3} \tilde{a}=\alpha^2a+2\alpha p^{\prime}(x) b+(p^{\prime}(x))^2c \end{aligned}$$ $$\begin{aligned} \label{eq4} \tilde{b}=\alpha b+p^{\prime}(x) c \end{aligned}$$ First, assume that $c\neq0$. From we get $p^{\prime}(x)=\frac{\tilde{b}-\alpha b}{c}$ giving $p(x)=(\frac{\tilde{b}-\alpha b}{c})x$, and inserting $p^{\prime}(x)$ in we obtain $$\begin{aligned} \tilde{a}&=\alpha^2a+2\alpha\Big(\frac{\tilde{b}-\alpha b}{c}\Big) b+\Big(\frac{\tilde{b}-\alpha b}{c}\Big)^2c =\alpha^2a+\frac{2\alpha b \tilde{b}-2\alpha^2 b^2}{c} +\frac{\tilde{b}^2c-2\alpha b \tilde{b}c+\alpha^2 b^2 c}{c^2} \end{aligned}$$ Multiplying both sides by $c^2$, we
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. Chris works at the Wayne Co. Highway Dept. and I work for Richmond Community Schools as a principal. Phillip is a second grader at Western Wayne Elementary and Hattie loves going to preschool with Ms. Tonya. Phillip loves baseball, basketball, and 4-H. Hattie loves baby dolls and following her bubbie. We are attending Christ Jesus Community Church and are growing up in God daily. Our lives have been blessed by the friends we met at Farmland Friends. Which led us to find a church that provides instruction with fellowship. We have searched for a place our children can be involved in a church youth group. The Pastor at our new church, Fuzzy, was my youth pastor growing up. We hope you enjoy reading and catching up with us through this blog.At Color Bar, it’s about the experience! We are a spa-salon that offers a wide range of services including haircuts, colors, highlights, keratin straightening, hair extensions, massages, couples massages, facials, makeup applications in a relaxed, comfortable atmosphere! Our highly trained service providers are more than just stylists, but they embrace an artistic approach to every client they meet with. Our welcoming atmosphere allows for everyone to feel at ease to ensure that they are able to relax for a few hours away from the hustle and bustle of life. Every service is completely customized to your individual needs. Our stylists and skin care providers are always one step ahead in the industry, from staying on top of the most prestigious continued education classes from all around the country. We are located in downtown Peabody MA with convenient parking located across the street. Call us at 978.854.6388 to book your appointment today. CHRISTINEChristine is the Co-Owner of Color Bar Salon & Spa. She has been in the industry since 1994. Her specialties include Advanced Coloring, Creative foils techniques, Corrective Color Expert Woman cuts, and Keratin complex smoothing therapy by Coppola. Advanced Training • Redken Advanced Color Certified • Advanced foiling certified • Redken/Matrix/Bumble & Bumble product knowledge classes • Rejovenol Certified • Coppola Certified • Extensions Certified • Cutting technique classes JANELJanel is a Co-Owner and has been in the industry since 2005. Her specialties include Specialty Blowdry / Color and Foil Techniques, Cutting Techniques, and Formal Styles. Advanced Training • Extensions / Foil / Color Certified • Keratin Complex smoothing Therapy by Coppola • Rejuvenol/Coppola Certified • Redken & Paul Mitchell product knowledge cases NICOLENicole has been in the industry since 2009. She specializes in Specialty Manicures, Pedicures, Shellac, & Gel Polish Nail Art. Advanced Training • Certified as a Nail Tech in February, 1999 with Beauty Creators Academy of Everett, MA. • While concentrating on natural nail care, I am constantly keeping up with the latest nail trends. I enjoy experimenting with nail art and unique color combinations for accent nails. LISALisa has been in the industry since 1995 and is currently both the Color Bar’s personal assistant who maintains the front desk and a stylist. She is there for all the clients and to make their visit the greatest salon experience they have ever had. Advanced Training • Keratin Complex Certified ELYSEElyse obtained her asthetics license in 1998 and pursued her career in skincare. Palmer Institute for Massage Therapy in Salem. Master Lash Stylist starting out with Xtreme Lash in 2003.Specialties In 2006 she was trained and certified at Palomar Industries on Pulsed Light Laser Treatments which include Hair Removal and Photo-Facials. Bridal and Special Occassion Make-up application, Eyelash Application and Laser Hair Removal and Photo-Facial Treatments. VANESSAVanessa has been in the industry since 2009. She is very passionate about her work and specializes in all formal events and foiling techniques. She is also experienced with Babe hair extensions. Vanessa continues her education to keep up with the latest trends.More people in the United States are apparently leaving wedding rings sitting in jewelry stores, as new data shows a majority of American adults are now single. Specifically, about 50.2 percent of American adults over the age of 16 – roughly 124.6 million people – were single in August, according to a new Bureau of Labor Statistics report cited by Bloomberg. This marks the first time that single Americans make up the majority of the adult population since the government began tracking the data 38 years ago. In 1976, single Americans made up 37.4 percent of the adult population. The number of individuals who have never been married also rose to 30.4 percent, up notably from 22.1 more than three decades ago. Divorced Americans, meanwhile, now compose 19.8 percent of the population, compared to 15.3 percent in 1976. As these numbers continued to rise, economist Edward Yardeni said the development will have significant ripple effects for the economic, social and political scenes in the United States. According to Yardeni, who penned a letter to clients on Tuesday, single Americans as a group generally prefer to rent housing rather than own it outright, and they are less likely to have children. These trends mean that changes in spending will also be on the way. Although single Americans were not yet the majority in 2012, a report by Fortune at the time had already started documenting some of these changes, noting that so-called “Singletons” were contributing close to $2 trillion to the US economy every year. “They spend more discretionary dollars than their married counterparts,” Eric Klinenberg wrote for the magazine. “Their average per capita annual expenditure was $34,471 in 2010, according to the federal Consumer Expenditure survey, compared with $28,017 for married individuals without kids and $23,179 per person in the highest-spending families with children.” Yardeni also said that the rise of single households could be making the income inequality gap seem worse than it really is. “While they have less household earnings than married people, they also have fewer expenses, especially if there are no children in their households,” Yardeni wrote, according to Bloomberg. As single people are bolstering the economy in some ways, a continued trend of childless households could also mean significant challenges for the US population in the long term. As noted by TheBlaze, the choice to have fewer children has left countries like Japan facing big demographic problems, as fewer people are left to replace those who retire and leave the workforce. Meanwhile, the Census Bureau found that in 2013, the US population grew at its lowest rate since the Great Depression, primarily due to low birth rates and lower immigration activity as a result of a slow economic recovery.Exemplary embodiments pertain to the art of passive bleed valves and more specifically to a segmented spring guide for a piston within a pneumatic passive bleed valves assembly. Pneumatic passive bleed valves in aircraft engines use springs with varying degrees of success. Such valve include a piston that is held in place by a spring and the motion of the piston causes the spring to compress. With pneumatic passive bleed valves on aircraft engines, a compressed spring may endure high levels of vibration in a low damping medium such as air. A resulting axial resonance may cause high cycle fatigue and wear failures.Case report: use of topical tranexamic acid to stop localised bleeding. A case is presented in which topical tranexamic acid was used to stop local bleeding from a nipple following piercing in a young man with haemophilia. This case, with a review of the relevant literature, highlights the use of topical tranexamic acid as part of a methodical approach to stop localised, non-massive bleeding, particularly in patients with inherited or acquired coagulopathies. [PUBLISH] IN THE UNITED STATES COURT OF APPEALS FOR THE ELEVENTH CIRCUIT FILED U.S. COURT OF APPEALS ELEVENTH CIRCUIT MAY 11 2000 THOMAS K. KAHN No. 99-10782 CLERK D. C. Docket No. 97-807-CV-ASG DAVID RUTSTEIN, Plaintiff, ZEREI AGUDATH ISRAEL BOOKSTORE, LEVI SUFRIN, Plaintiffs-Appellees, versus AVIS RENT-A-CAR SYSTEMS, INC., a Delaware Corporation, authorized to do business in the State of Florida, Defendant-Appellant. Appeal from the United States District Court for the Southern District of Florida (May 11, 2000) Before TJOFLAT, Circuit Judge, RONEY and FAY, Senior Circuit Judges. TJOFLAT, Circuit Judge: Jewish plaintiffs1 brought this civil rights lawsuit in the United States District Court for the Southern District of Florida on behalf of themselves, and all others similarly situated, against Avis Rent-A-Car System, Inc. (“Avis”). Plaintiffs alleged that Avis had denied them their right to make and enforce contracts because of their race, ancestry, and ethnic characteristics,2 in violation of 42 U.S.C. § 1981 (1994).3 They sought compensatory damages, punitive damages, and injunctive
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mid 2016. I’d also love to finish a curriculum I started a few years ago. That latter one is probably a bit too ambitious for 2016, but I can dream, can’t I? The website will be getting a makeover with a new theme which is much more capable for future plans (and will better support a podcast). It should make publishing new content easier and more fun, which should help the goal of producing content on a more consistent basis. Which brings me to… An appeal for support I’d love to have a lot more time to create content for TilledSoil. Up until now, I’ve done most of what you see here (as well as a lot you don’t see here) out of love for Christian apologetics, and to play my part in Christian evangelism. But, realities of life have forced me to put less and less time into this ministry, and more into things that make a living. We can tilt that balance back in this direction, but I need your help! To that end, I have set up a Patreon account and page to raise funds to keep this ministry going… and hopefully growing! I’d love to put much more of my time, if not all, into this effort. Ultimately, I’d like to be able to replicate the local aspect of the model, and establish trained Christian apologists in various geographical areas to support local churches. That’s my dream, but I can’t do it alone. Patreon is a service that makes it easy for patrons to pay each time content is produced, or setup a monthly subscription. I’m asking for monthly support at this point, though Patreon will allow for a lot of fund-raising flexibility as we grow. And, you can start with as low as $1/month or as much as you like. I’ve heard you don’t get, if you don’t ask… so I’m asking. Just click the Patreon logo below. Thank you in advance! Note: If you would rather make a one-time donation, please contact us, but consistent monthly support is preferred, as it gives us a better measure of where we’re at. We also currently do not have non-profit or charity status, so any donations, while greatly appreciated, will not be tax deductible.(1)Gaining such status is expensive, complex, and time-consuming. We welcome input, but we’re also not sure such status won’t be a burden in the coming years, given the direction of our society. ]]>I will be speaking at the Science and Faith Symposium in Prince George BC Canada on the topic: Creation vs Evolution: 4 views. This event will be held on Sunday evening, June 7th from 7-9 pm at Our Saviour’s Lutheran Church in Prince George, BC Canada. Please see OSLC’s website for details or contact information. The cost for the event is free, and I’ll be joined by two other speakers, Art Betke on Limits to Evolution, and John MacDonell on Evolution Revolution. The primary purpose for this event is to get people discussing this important topic. The speakers will present an overview of the various positions, discuss how to think about such topics in a clear and compassionate manner, and present opposing views on the subject (i.e.: one creationist point of view and one evolutionist point of view). If you are in or around the Prince George, BC, Canada area, TilledSoil.org encourages you to attend, as we’ve been promoting this topic as an important subject to discuss in our churches. Often, because the issue can be divisive, it is avoided. We don’t believe ‘sweeping disagreement under the rug’ is healthy in any kind of relationship, let alone the church body or the relationship between church and culture. The Blind Watchmaker: Why the Evidence of Evolution Reveals a Universe without Design by Richard Dawkins | on Amazon.ca The Greatest Show on Earth: The Evidence for Evolution by Richard Dawkins | on Amazon.ca My Journey (quotes and info) “Biology is the study of complicated things that give the appearance of having been designed for a purpose.” Richard Dawkins, The Blind Watchmaker, p4 – so, maybe the appearance of having been designed for a purpose is evidence it has been? What direction is the research moving? Who is actually holding up science? Does the person who is correct need to suppress other views? Vestiges of evolution… Scopes trial in 1925, argument was given that there were over 180 vestigial organs and structures in the human body. Now, scientists are wary of talking about vestigial organs at all. (ex: tonsils, tail-bone, thyroid, appendix.) “What pseudogenes are useful for is embarrassing creationists. It stretches even their creative ingenuity to make up a convincing reason why an intelligent designer should have created a pseudogene – a gene that does absolutely nothing and gives every appearance of being a superannuated version of a gene that used to do something — unless he was deliberately setting out to fool us. … Leaving pseudogenes aside, it is a remarkable fact that the greater part (95 percent in the case of humans) of the genome might as well not be there, for all the difference it makes.” Dawkins 2009 book The Greatest Show on Earth “Even more compelling evidence for a common ancestor comes from the study of what is known as ancient repetitive elements (AREs). … Mammalian genomes are littered with such AREs, with roughly 45% of the human genome made up of such genetic flotsam and jetsam. … Of course, some might argue that there are actually functional elements placed there by the Creator for a good reason, and our discounting them as ‘junk DNA’ just betrays our current level of ignorance.” Francis Collins, The Language of God, p135-136 The result: “Although very catchy, the term ‘junk DNA’ repelled mainstream researchers from studying noncoding genetic material for many years. After all, who would like to dig through genomic garbage? Thankfully, though, there are some clochards who, at the risk of being ridiculed, explore unpopular territories.”Scientific American “What is junk DNA, and what is it worth?” OEC models predicted function would be found, and just a couple years later, ENCODE project showed over 80% function and growing. YEC to OEC, but stopped before TE (my path) when I was growing up, YEC was the ‘official’ position of my church began to get pushed on this when starting in apologetics discussion discovered Hugh Ross’ ministry and found it very compelling was heavily encouraged to switch to Theistic Evolution in seminary but, I found the arguments of RtB and ID folks more compelling and, was really disappointed that, at the time, the TE camp hadn’t done their theology! While I respect science, I’m not bothered by disagreeing with the current neo-Darwinian consensus. ]]>http://www.tilledsoil.org/science-and-faith-symposium-in-prince-george-bc-canada/feed/0Identity Crisis: Should We Use the Term Apologetics?http://www.tilledsoil.org/identity-crisis-use-term-apologetics/ http://www.tilledsoil.org/identity-crisis-use-term-apologetics/#respondThu, 13 Nov 2014 22:04:56 +0000http://www.tilledsoil.org/?p=909Do you get blank stares when you mention apologetics? Should we find a new term? A look at how to help people understand us and build community. ]]>Do you get blank stares when you mention apologetics? Should we drop the term and find another, like case-maker? Having tried apologetics as well as other terms, I think the problem is deeper. What can we do, and what might we learn from others who share a similar identity problem? Should we find a new term? I’m not inherently opposed to replacing the term. Apologetics is derived from a Biblical Greek word used convey making a legal defense for a point of view (in this case our Christian faith). But, I don’t think it is important we insisting on it (like we might for terms such as justification, propitiation, or atonement). (1)Yes, I do think it is important we teach such terms, as something is always lost when we start substituting. In other words, it isn’t a term that is particularly unique or important in its own right. I’ve tried J. Warner Wallace’s suggestion of the term, ‘case-making.’ The problem is that I usually get similar blank stares. I’ve tried using the definition of ‘defending’ or ‘making a defense for’ Christianity. This sometimes results in a blank stare coupled with a negative reaction. I suppose defense seems a bit more militant. In many cases, confusion concerning apologetics isn’t a matter of difficult terminology, but of a struggle to fit the concept into a particular understanding of Christianity. If I were an endocrinologist, I’d probably have to explain that term at dinner parties. But, once I told them I was a doctor who worked with the body’s system of hormones, and had patients
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giorno di Jahvè» quando solo coloro che invocano il nome di Jahvè saranno salvati, verrà infuso su tutti i membri della comunità, i loro figli, le loro figlie, i loro servi e serve; susciterà sogni negli anziani, visioni nei giovani, e darà il dono della profezia ai fanciulli. Qui si torna senza dubbio alle antiche tradizioni dell'estasi laica e la speranza finale viene quindi collegata al ritorno del dono universale della profezia. Tale concezioni è diventata importante per lo sviluppo del cristianesimo. Il miraco lo della Pentecoste viene narrato ( _Atti,_ 2, 16 e segg.) con riferimento a questo passo che viene citato per esteso. Evidentemente la missione cristiana dava tanto peso a questo miracolo solo perché in base ad esso l'imminenza del giorno «del Signore» (nella concezione cristiana) come lo aveva annunciato Gioele pareva certa. Per la devozione cristiana primitiva questo passo, e solo questo, nella letteratura profetica giudaica, legittimava lo «spirito» come fenomeno estatico di massa, caratteristico per la comunità cristiana in pieno contrasto con la profezia pre-esilica. 7. _1 sacerdoti e la restaurazione confessionale dopo l'esilio_ Nello sviluppo del giudaismo questi passi mostrano soltanto che il genuino «spirito» dell'antica profezia stava scomparendo. Non scomparve in modo misterioso, per via di qualche legge psichica «immanente». Ma scomparve perché il potere poliziesco dei sacerdoti in seno alla comunità giudaica riuscì a dominare la profezia estatica proprio come l'ufficio vescovile e presbiteriale si era imposto alla profezia pneumatica nella comunità protocristiana. Il carisma della profezia estatica è continuato a sussistere nel giudaismo. Le visioni attribuite a Daniele ed Enoch sono di carattere estatico così come pure numerose esperienze di altri apocalittici, anche se gli stati psichici, come pure la loro interpretazione, si scostano molto dall'antica profezia; inoltre la forma artistica letteraria prende nettamente il sopravvento sull'attuale esperienza emotiva. Ma tra tutti questi scritti posteriori solo il Libro di Daniele si è guadagnato il riconoscimento ufficiale che ha costretto ad includerlo nel canone. Tutti gli altri sono stati tollerati ma considerati lavori privati non-classici o addirittura eterodossi. L'attività di questi veggenti diventò quindi un affare di sètte e comunità misteriche. Del pari è esistita fino alla fine del secondo tempio una profezia che si occupava degli affari politico-religiosi del momento. Nell'opinione popolare il dono profetico conservava fermamente il suo carattere divino e tutti i profeti avevano un pubblico. Ma i sacerdoti erano sempre in contrasto con loro. I rappresentanti della profezia politica erano ostili alla riforma sacerdotale di Esdra e Neemia. Degli oracoli di questi profeti non è stato conservato nulla: i sacerdoti recepivano soltanto ciò che si adattava all'organizzazione sacerdotale della comunità. Il discredito del carisma profetico era in certa misura facilitato dal fatto che gli oracoli si contraddicevano a vicenda. Già il contrasto tra gli oracoli di Isaia e Michea, Isaia e Geremia, Geremia e Ezechiele, doveva aver scosso la credenza che ogni estasi profetica in sé offrisse la garanzia intrinseca di essere portatrice di messaggi divini. Come si poteva riconoscere, allora, l'autenticità della profezia? L'esperienza mostrava che anche falsi profeti avevano posseduto poteri miracolosi ( _Deut.,_ 13, 3). A partire dai deuteronomisti (18, 22) la risposta data alla domanda era: con l'avverarsi della predizione. Ma questo non era un criterio utile per il periodo di attesa di questa verifica, che era proprio il periodo che importava. Di conseguenza Geremia (23, 22) ha fornito un secondo criterio: il profeta è autentico solo se corregge i peccatori, legando quindi la comunità a Jahvè e alla sua legge; altrimenti è un profeta di menzogna. Questo concetto ancora una volta trova il suo parallelo nel ruolo crescente del criterio etico nella comunità protocristiana. Il rispetto fermamente inculcato per l'opera della _Tor ah_ levitica portava qui i suoi frutti nella comunità giudaica come più tardi la recezione dell'«Antico Testamento» nella comunità cristiana. In seno alla comunità post-esilica i sacerdoti riuscirono ad infrangere completamente il prestigio dell'antica estasi del _navi_. Il risultato appare nello scherno del Deuterozaccaria per i profeti come portatori dello spirito «d'impurità» (13, 1 e segg.). Il giorno di Jahvè, insieme agli idoli anche i profeti saranno cacciati dal paese. Chi assume il contegno del profeta sarà smascherato e trafitto dai propri genitori come truffatore, si vergognerà delle sue visioni, non indosserà più il mantello di pelo (manto profetico), ammetterà di essere un contadino e che le sue presunte stimmate provengono dalle unghie delle meretrici. Sotto questa forma di sprezzante autoderisione della profezia la versione sacerdotale costrinse questa pericolosa concorrente a togliersi da sé la vita. Come nella Chiesa cristiana burocratizzata, così d'ora in poi anche nel giudaismo ufficiale l'epoca profetica venne considerata chiusa, lo spirito profetico estinto: è lo stesso sviluppo che si verifica dappertutto con il pieno sviluppo della gerarchia sacerdotale che si assicura così contro le innovazioni religiose. L'espressione _rtiach ha-kodesh_ (nella Septuaginta πνεῦμα τὸ ἅγιν, «spirito santo «) che compare per la prima volta nel Tritoisaia in uno dei più rigorosi sermoni di penitenza profetici (63, 10-11) viene di nuovo concepita in un salmo di penitenza profondamente pessimista (51, 13), come una disposizione di colui che sta nella grazia di Jahvè. La colomba, simbolo di Israele perseguitato ( _Salmo,_ 74, 19), viene utilizzata nello stesso tempo dai rabbini come portatrice di questa disposizione che è altrettanto profondamente diversa, interiormente, dal pneuma emotivo cristiano quanto dall'antico spirito profetico che secondo la dottrina posteriore non è più stato ottenuto da nessuno dopo Malachia. è vero che anche adesso, se Dio vuole, si può udire una misteriosa voce celeste ( _bath kol_ ) sotto forma di forte appello o lieve mormorio. Ma udirla non è un dono profetico. Infatti essa si fa sentire secondo le circostanze dai peccatori come dai giusti e dai maestri, così come avviene pure nel Nuovo Testamento, annunciando la sventura o la felicità e la grandezza o chiam
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to reduce chlorides in an aminopolyamide-epichlorohydrin resin as disclosed in Devore et al. U.S. Pat. Nos. 5,239,047 and 5,189,142.Electoral district of Maryborough and Daylesford The Electoral district of Maryborough and Daylesford was an electoral district of the Victorian Legislative Assembly. It included the towns of Maryborough and Daylesford, around 168 km and 155 km north-west of Melbourne respectively. It was created when the electoral districts of Maryborough and Daylesford were combined in 1927; George Frost was the last member for Maryborough. Members for Maryborough and Daylesford See also Parliaments of the Australian states and territories List of members of the Victorian Legislative Assembly References Category:Former electoral districts of Victoria (Australia) Category:1927 establishments in Australia Category:1945 disestablishments in AustraliaMansions - Doom Loop Even though he’s always been particularly wise, it’s strange to think of Christopher Browder as old. His songs were always one of self-help and self-reflection, but from a place of seemingly eternal youth. With Doom Loop, Browder has packed in layers of fuzz, some grunge and plenty of catchy melodies. And although he’s hovering around the 30 year old-mark, his beleaguered, high-pitched moan hasn’t aged a day. Doom Loop is garnering some much-deserved attention, and rightfully so, but as a fomerly sad college student who reviewed Mansions' New Best Friends back in 2009, this album sounds like the culmination of a kid growing into the man he’s somehow always been. In a recent listicle on Pop Matters, Browder said that his favorite record of all time is Weezer’s Pinkerton, which I didn’t know, but which is also not shocking in the least. 90’s alt-rock and grungy flannel tunes are all over Doom Loop. And what has become his real signature – asking questions when he already knows the answer – is very Rivers Cuomo. Through songs like fuzzy “Two Suits” and the very loud take on being tired, “Climbers,” Mansions have shifted their sights ever-so-slightly to simplicity. And that’s not meant to be condescending, it’s just to say that Doom Loop has quite a bit of fun rock and anti-social language that never sounds like Mansions are grasping to change things up. It’s a different sounding record than even Dig Up The Dead, but it’s also natural. Then there’s the relentless headbanger “The Economist.” The second its riff comes in, you’re just ready to be at a Mansions concert, which is honestly not something I’ve thought before. Yes, they’ve done rock and fast and catchy, but “The Economist” is on another level of lo-fi loud. All of that stuff I said about growing old, well, this is the sort of song that can only be made by someone with endless youth. So Browder is getting older and learning new tricks, but there’s something awfully life-affirming about lyrics like, “Cause I’ve been sleeping so long / I’m up on a stage / Scream myself hoarse…Turn around and you’ll get replaced.” It’s the future that’s brightest, and the bridge of this song plays like a sort-of set-up to Mansions’ inevitable post-Doom Loop career. As Mansions stockholders, we’ve got a lot to look forward to. All over Doom Loop – the power-pop of “If You’re Leaving, the slow-burning downer “100 Degrees” – Mansions deviate from the formula of angsty tunes just enough to make this rock with no need for descriptors. That’s possible because of the band’s voracious knowledge of popular music, and their incredible ability to imitate and mix styles on the fly. Mansions have a sound you can notice from across the bar, but there’s still songwriting distinction here. And Doom Loop is probably the band’s most ownable, and I suspect, most fully realized effort. It’s another reassuring testament to the fact that creativity isn’t a well, but a fountain. 8/10 Recommended If You Like: Weatherbox, Into It. Over It., Weezer, The Front Bottoms Great review. This album is everything I could have hoped for as a follow up to DUTD. Definitely agree about "The Economist" making you yearn to be at a Mansions concert. I'm dying to hear that and "Out for Blood" live. I mean, they recorded everything but the drums on this album in an apartment, so... By dorm room I meant the topics he handled and they way he processed them through his songwriting. It was all very nostalgic - this album is more grown-up. Before we enter the "people mature" conversation, I'm aware of that. I just happen to like his older stuff more.Q: Pass job name and build number to cloudbees application I want to be able to use the job and build number within my cloudbees application (i.e access it as an environment variable). In the application description, I can use "${JOB_NAME} #${BUILD_NUMBER}", but is this also possible somehow within the environment override fields? I want to be able to set something like: Name: runningversion Value: ${JOB_NAME} #${BUILD_NUMBER} A: I am assuming you are using the CloudBees Deployer plugin to deploy your application to our RUN@cloud service. If that is the case then you can achieve exactly what you want with the Override Environment section. You just need to do something like this: The in-line help for the Value field even indicates that it Supports ${} style token macro expansion As a hint to let you know that you can do what you are trying to do... so if it doesn't work then there is a bug! Those Override Environment name-value pairs should be available, at least, as OS level environment variables and for the Java based ClickStacks (e.g. Tomcat, JBoss, Glassfish, Play, etc) they should also be available as Java System Properties but that can require that the ClickStack is written to provide that support (the well known ones produced by CloudBees should) Age-Related Changes in Cardiovascular Function Associated with Electroconvulsive Therapy. The relationship between hemodynamic changes induced by electroconvulsive therapy (ECT) and age was studied in 13 patients. Their average age was 43 years (range 20-64 years). Heart rate, arterial blood pressure, and rate-pressure product (RPP) all increased significantly following ECT. There was an inverse relationship between age and the magnitude of the chronotropic response, the percentage increase in diastolic and mean arterial blood pressure, and the RPP. Duration of the electroencephalographic and motor seizures was also inversely related to age.Cognitive function and associated factors among older people in Taiwan: age and sex differences. The aim of this study was to examine cognitive function and the risk and the protective factors by age and sex among Taiwanese older people. The data were from a nation-representative panel of older people in Taiwan. The participants completing both the 2003 and 2007 waves were included for analysis in this study (n=3228). Descriptive analysis and generalized linear model were applied, and the samples were stratified by age groups and by sex. The factors related to higher cognitive function at the intercept included being younger, male, higher education, and doing unpaid work. At the time slope, the age effect and physical function difficulties would reduce the cognitive function across time, while education and providing informational support would increase the cognitive function across time. There were age- and sex-differences in the factors related to cognitive function, particularly on the working status and social participation. Different health promotion strategies to target these populations should be accordingly developed.Q: SwiftUI UIScrollView Detect when user scrolls near the bottom Im trying to detect when the user is scrolling and he arrives near to the bottom so I can load my next batch of data. I have implemented scrollViewDidScroll(_ scrollView: UIScrollView) but nothing happens. The only time it gets trigger is when I pull up the screen after I'm at the bottom. So I need to go past the bottom in order for it to be triggered. What am I doing wrong here? import SwiftUI struct RequestsListView: View { @ObservedObject var requestsViewModel: RequestsViewModel var body: some View { List { ForEach(requestsViewModel.requests) { (request: Request) in if let item = request.item { RequestRowView( requestViewModel: RequestViewModel(request: request), itemViewModel: ItemViewModel(item: item) ) .onAppear() { if let index = requestsViewModel.requests.firstIndex(where: {$0.id == request.id}), index == 0 { print("load more") //requestsViewModel.load() } } } } } .onAppear() { print("initial
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1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.016120e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=18 NB=78 KB=179 KVEC=1 \ AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-1.947380e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=18 NB=78 KB=180 KVEC=1 \ AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-1.958260e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=108 NB=192 KB=181 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-1.997279e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=18 NB=144 KB=182 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.007312e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=12 NB=144 KB=183 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.001625e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=108 NB=192 KB=184 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.017884e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=54 NB=162 KB=185 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.018067e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=54 NB=162 KB=186 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.028976e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=54 NB=150 KB=187 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.024119e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=54 NB=150 KB=188 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.034943e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=12 NB=222 KB=189 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.017874e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=12 NB=222 KB=190 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.028551e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=108 NB=192 KB=191 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.029872e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=108 NB=192 KB=192 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.040499e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=42 NB=204 KB=193 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.029841e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=42 NB=204 KB=194 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.040358e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=48 NB=192 KB=195 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.026103e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=64 KU=2 NU=6 MU=6 MB=48 NB=192 KB=196 \ KVEC=1 AOUTER=1 KRUNTIME=1 LDCTOP=1 \ MFLOP=-2.036493e+04 ID=0 ROUT='ATL_tmp.c' AUTH='R. Clint Whaley' TA='T' TB='N' \ OPMV=13 VLEN=2 KBMIN=2 IVAR=
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at the contact information noted above by October 29, 2012 for the teleconference so that the information may be made available to the Panel members for their consideration. Written statements should be supplied in one of the following electronic formats: Adobe Acrobat PDF, MS Word, MS PowerPoint, or Rich Text files in IBM-PC/Windows 98/2000/XP format. It is the SAB Staff Office general policy to post written comments on the Web page for the advisory meeting or teleconference. Submitters are requested to provide an unsigned version of each document because the SAB Staff Office does not publish documents with signatures on its Web sites. Members of the public should be aware that their personal contact information, if included in any written comments, may be posted to the CASAC Web site. Copyrighted material will not be posted without explicit permission of the copyright holder. Accessibility:For information on access or services for individuals with disabilities, please contact Dr. Holly Stallworth at (202) 564-2073 [email protected] request accommodation of a disability, please contact Dr. Stallworth preferably at least ten days prior to the teleconference to give EPA as much time as possible to process your request. The public teleconferences will be held on Wednesday December 5, 2012 and Friday December 7, 2012. The teleconferences will be held from 2:00 p.m. to 5:00 p.m. (Eastern Standard Time) on both days. ADDRESSES: The teleconference will be conducted by telephone only. FOR FURTHER INFORMATION CONTACT: Any member of the public who wants further information concerning the meeting may contact Mr. Thomas Carpenter, Designated Federal Officer (DFO), EPA Science Advisory Board (1400R), U.S. Environmental Protection Agency, 1300 Pennsylvania Avenue NW., Washington, DC 20460; via telephone/voice mail(202) 564-4885; fax (202) 565-2098; or email [email protected]. General information concerning the SAB can be found on the SAB Web site athttp://www.epa.gov/sab. SUPPLEMENTARY INFORMATION: Background:Pursuant to the Federal Advisory Committee Act (FACA), as amended, 5 U.S.C., App., notice is hereby given that the SAB Perchlorate Advisory Panel will hold a public teleconferences to discuss its draft report regarding EPA's draft white paperLife Stage Considerations and Interpretation of Recent Epidemiological Evidence to Develop a Maximum Contaminant Level Goal (MCLG) for Perchlorate. The SAB was established pursuant to 42 U.S.C. 4365 to provide independent scientific and technical advice to the Administrator on the technical basis for Agency positions and regulations. The SAB is a Federal Advisory Committee chartered under FACA. The SAB will comply with the provisions of FACA and all appropriate SAB Staff Office procedural policies. The SAB Perchlorate Advisory Panel held a public meeting on July 18-19, 2012 to discuss the EPA white paper and a public teleconference on September 25, 2012 to discuss its initial draft (9/5/21012) report. The purpose of these public teleconferences is for the Panel to discuss its revised draft report on this advisory activity. Additional background on this SAB advisory activity is provided on the SAB Web site at:http://yosemite.epa.gov/sab/sabproduct.nsf/fedrgstr_activites/Perchlorate%20MCLG%20Approaches?OpenDocument.” Availability of Meeting Materials:A meeting agenda, draft report, and other materials for the teleconferences will be posted on the SAB Web site atwww.epa.gov/sab. Procedures for Providing Public Input:Public comment for consideration by EPA's federal advisory committees and panels has a different purpose from public comment provided to EPA program offices. Therefore, the process for submitting comments to a federal advisory committee is different from the process used to submit comments to an EPA program office. Federal advisory committees and panels, including scientific advisory committees, provide independent advice to EPA. Members of the public can submit relevant comments pertaining to the group conducting this advisory activity, EPA's charge, or meeting materials. Input from the public to the SAB will have the most impact if it consists of comments that provide specific scientific or technical information or analysis for the SAB to consider. Members of the public wishing to provide comment should contact the Designated Federal Officer for the relevant advisory committee directly. Oral Statements:In general, individuals or groups requesting an oral presentation at a public teleconference will be limited to three minutes per speaker. To be placed on the public speaker list for the December 5, 2012 meeting, interested parties should notify Mr. Thomas Carpenter, DFO, by email no later than November 28, 2012. Written Statements:Written statements for these teleconferences should be received in the SAB Staff Office by the same deadlines given above for requesting oral comments. Written statements should be supplied to the DFO via email (acceptable file format: Adobe Acrobat PDF, MS Word, WordPerfect, MS PowerPoint, or Rich Text files in IBM-PC/Windows 98/2000/XP format). It is the SAB Staff Office general policy to post written comments on the web page for the advisory meeting or teleconference. Submitters are requested to provide an unsigned version of each document because the SAB Staff Office does not publish documents with signatures on its Web sites. Members of the public should be aware that their personal contact information, if included in any written comments, may be posted to the SAB Web site. Copyrighted material will not be posted without explicit permission of the copyright holder. Accessibility:For information on access or services for individuals with disabilities, please contact Mr. Carpenter at the phone number or email address noted above, preferably at least ten days prior to the meeting, to give EPA as much time as possible to process your request. Notice is hereby given that the State of Florida is revising its Public Water System Supervision Program by adopting the Lead and Copper Rule Short Term Revisions. EPA has determined that Florida's rule is no less stringent than the corresponding federal regulations. Therefore, the EPA is tentatively approving this revision to the State of Florida's Public Water System Supervision Program. DATES: Any interested person may request a public hearing. A request for a public hearing must be submitted by November 19, 2012, to the Regional Administrator at the EPA, Region 4 address shown below. The Regional Administrator may deny frivolous or insubstantial requests for a hearing. However, if a substantial request for a public hearing is made by November 19, 2012, a public hearing will be held. If the EPA, Region 4 does not receive a timely and appropriate request for a hearing and the Regional Administrator does not elect to hold a hearing on her own motion, this tentative approval shall become final and effective on November 19, 2012. Any request for a public hearing shall include the following information: The name, address, and telephone number of the individual, organization, or other entity requesting a hearing; a brief statement of the requesting person's interest in the Regional Administrator's determination; a brief statement of the information that the requesting person intends to submit at such hearing; and the signature of the individual making the request, or, if the request is made on behalf of an organization or other entity, the signature of a responsible official of the organization or other entity. ADDRESSES: All documents relating to this determination are available for inspection between the hours of 8:30 a.m. and 4:30 p.m., Monday through Friday, at the following offices: Florida Department of Environmental Protection, Drinking Water Program, 2600 Blair Stone Road, Tallahassee, Florida 32399; and the U.S. Environmental Protection Agency, Region 4, Safe Drinking Water Branch, 61 Forsyth Street SW., Atlanta, Georgia 30303. EPA Analysis On October 12, 2010, the State of Florida submitted a request that the Region approve revisions to the State's Safe Drinking Water Act PWSS Program to include the authority to implement and enforce the Lead and Copper Rule Short Term Revisions. EPA reviewed the application using the federal statutory provisions (Section 1413 of the Safe Drinking Water Act), federal regulations (at 40 CFR part 142), stateregulations, rule crosswalks and EPA guidance to determine whether the request for revision is approvable. Florida has chosen to not allow certain options set forth in the federal regulations, to extend time frames for certain activities. There are specific State regulatory provisions indicating the State is not allowing the option to extend those time frames. In addition, Florida has chosen to implement an optional federal requirement regarding submittal of certain information. These choices are consistent with and no less stringent than the federal requirements. EPA Action:The EPA is tentatively approving this revision. If EPA does not receive a timely and appropriate request for a hearing and the Regional Administrator does not elect to hold a hearing on her own motion, this tentative approval will become final and effective on November 19, 2012. FOR FURTHER INFORMATION CONTACT: Mr. Larry Meyer, EPA, Region 4, Safe Drinking Water Branch, at the address given above, or by telephone at (404) 562-9449, or via email [email protected]. Authority: Section 1413 of the Safe Drinking Water Act, as amended (1996), and 40 CFR part 142. The FDIC, as part of
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MM's expenses were only.53% of its average net assets. As a result, the Fund's yield for the year ended September 30, 1984 was approximately 21 basis points less than that of MM. (Compl. ¶ 12). [7] Section 20(a) was part of the original Investment Company Act passed in 1940. [8] All of the cases discussing an implied right of action under § 20(a) have arisen in the Second Circuit. [9] See, e.g., Gartenberg v. Merrill Lynch Asset Management, Inc., 528 F.Supp. 1038, 1067 (S.D. N.Y.1981), aff'd, 694 F.2d 923 (2d Cir.1982), cert. denied, 461 U.S. 906, 103 S.Ct. 1877, 76 L.Ed.2d 808 (1983) ("Gartenberg I"); Tarlov v. Paine Webber Cash Fund, Inc., 559 F.Supp. 429, 437 (D.Conn.1983). [10] In this respect, Kamen's complaint fails to satisfy the requirements of Fed.R.Civ.P. 10(b), which requires "that each claim founded upon a separate transaction or occurrence... shall be stated in a separate count." [11] The court disagrees with KFS' argument that allowing § 20(a) claims in the context of excessive fee suits would thwart the intent of Congress when it passed § 36(b). According to KFS, allowance of a § 20(a) claim would undermine the procedural restrictions contained in § 36(b). What KFS fails to acknowledge is that a § 20(a) claim exists independent of a § 36(b) claim, and involves different elements of proof. Not all § 36(b) claims involve misleading proxies, and a plaintiff needs a misrepresentation in a proxy statement if she wishes to proceed under § 20(a). [12] The court notes that the Second Circuit has issued another decision subsequent to Gartenberg II which allowed § 20(a) claims without mention of the possible limitation imposed by § 36(b). See Meyer v. Oppenheimer Management Corp., 764 F.2d 76 (2d Cir.1985). [13] The ICA provides that "No registered investment company shall have a board of directors more than 60 per centum of the members of which are persons who are interested persons of such registered company." 15 U.S.C. § 80a-10(a). Section 2(a)(19) of the Act defines an interested person as follows: (19) "Interested person" of another person means — (A) when used with respect to an investment company (i) any affiliated person of such company, (ii) any member of the immediate family of any natural person who is an affiliated person of such company, (iii) any interested person of any investment adviser of or principal underwriter for such company, (iv) any person or partner or employee of any person who at any time since the beginning of the last two fiscal years of such company has acted as legal counsel for such company, (v) any broker or dealer registered under the Securities Exchange Act of 1934 or any affiliated person of such a broker or dealer.... Provided, That no person shall be deemed to be an interested person of an investment company solely by reason of (aa) his being a member of its board of directors or advisory board or an owner of its securities, or (bb) his membership in the immediate family of any person specified in clause (aa) of this proviso;.... 15 U.S.C. § 80a-2(a)(19). [14] Plaintiff also alleges that the president of the Fund is a former president of KFS and a stockholder of KFS's parent, Kemper Corporation. The court questions the relevance of this information on the issue of a demand, since plaintiff does not allege that Hawkinson is even a member of the Fund's Board of Directors. The fact that an officer of the Fund had a former affiliation with KFS does not have any bearing on the number of "interested" directors because he would only participate in the Board's decision to pursue the action if he were a director of the fund. [15] The demand would not be excused even if Kamen had named the individual directors in her complaint. The courts have uniformly held that, absent allegations of bias or self-interest, naming the individual directors cannot obviate the demand requirement of Rule 23.1. See generally Lewis v. Graves, 701 F.2d 245, 249 (2d Cir.1983); Lewis v. Curtis, 671 F.2d 779, 785 (3d Cir.), cert. denied, 459 U.S. 880, 103 S.Ct. 176, 74 L.Ed.2d 144 (1982); Lewis v. Sporck, 612 F.Supp. 1316, 1322 (N.D. Cal.1985); Kaufman v. Safeguard Scientifics, Inc., 587 F.Supp. 486, 489 (E.D.Pa.1984). [16] The Fund has joined Kemper in its motion to dismiss Kamen's § 20(a) claim for failure to make a demand and for failure to state a cause of action. [17] This court echoes the Seventh Circuit's query in Nussbacher: "It may be wondered why counsel would not almost routinely take the course of making a formal demand, diligently and in good faith, and in so doing inform the board adequately of the basis of the claim he was asking them to enforce." 518 F.2d at 877. [18] KFS recently filed a motion for summary judgment on the issue of whether Kamen can fairly and adequately represent the other shareholders in this action. [19] Kamen argues that § 36(b)'s reference to "damages," and her request for "damages" renders her claim an action at law. This argument has been rejected by every court that has considered it. With respect to the fact that the statute uses the word "damages," the Gartenberg court held: [I]t seems likely from the context that Congress was using `damages' merely as a shorthand for `recovery of money,' not as a legal term of art. Since... not all claims for monetary relief are legal in nature, the use of the term `damages' is not persuasive in this instance. In particular, given the repeated statement in the legislative history that actions under 36(b) are equitable, to be administered on equitable standards, it would seem impossible to conclude from the use of the word `damages' that Congress thereby provided for a trial by jury. Gartenberg v. Merrill Lynch Asset Management, Inc., 487 F.Supp. 999, 1006 (S.D.N.Y.), mand. denied sub nom. In re Gartenberg, 636 F.2d 16 (2d Cir.1980), cert. denied, 451 U.S. 910, 101 S.Ct. 1979, 68 L.Ed.2d 298 (1981). See also In re Evangelist, 760 F.2d 27, 30 (1st Cir.1985). Although the Evangelist court was unequivocal in its denial of a right to a jury trial, the Gartenberg court qualified its decision in the last paragraph: "Our decision is limited, of course, to the facts of this case. We leave for another day a determination as to the right of a jury trial of a plaintiff making a bona fide claim for damages." In re Gartenberg, 636 F.2d at 18. Kamen argues that because her complaint seeks damages, she falls within this Gartenberg caveat. The Second Circuit has never explained this final comment to its opinion; however, the court finds that Kamen's Section 36(b) claim is no different than that advanced in Gartenberg. The fact that her complaint requests "damages" does not automatically render her claim an action at law. As the Evangelist court noted, [I]n our view, the right to jury trial cannot turn on the simple substitution of a different word. Dairy Queen, Inc. v. Wood, 369 U.S. 469, 477-78, 82 S.Ct. 894, 899-900, 8 L.Ed.2d 44 (1962) (`the constitutional right to a trial by jury cannot be made to depend on the choice of words used in the pleadings.').... Otherwise, any equitable action for money, say for restitution, could become a legal action by the use of the word `damages' in place of the word `restitution.' 760 F.2d at 31. The semantics of Kamen's complaint cannot reign over the substance of her Section 36(b) claim, which is an action seeking restitution for excessive fees paid to KFS. [20] Kamen also argues that Section 44 of the ICA, 15 U.S.C. § 80a-43, refutes KFS' argument regarding the availability of jury trials in § 36(b) suits. Section 44 confers jurisdiction on the federal courts over "all suits in equity and actions at law brought to enforce any liability or duty created by" the ICA, and authorizes the SEC to "intervene as a party in any action or suit to enforce any liability or duty created by, or to enjoin any non-compliance with, Section 36(b)..." Kamen maintains that these provisions indicate that actions under § 36(b) can be characterized as suits at
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learns and optimal the weights that receive the features from three sub-models to achieve the best effect of multi-label classification. Note that the output vectors of the three modules have the same dimensions. As a whole, our Weight Classifier is a three-layer non-fully connected network model. The number of nodes in the input layer is the sum of the number of output nodes of the three sub-models, and both the nodes of hidden layer and the nodes of out layer are the same as nodes of the output layer of the three sub-models, which are set according to different species and GO sub-ontology. From the perspective of a single GO classifier, the structure is shown in [Figure 2](#F2){ref-type="fig"}. For a specific GO classifier, the hidden node only accepts three features, which are from the corresponding position of the output vector of three sub-model, respectively, corresponding to the GO category, and to extract the corresponding area, we used a binary mask matrix to implement this connection control. The output node of the Classifier also only receives the output of the corresponding hidden node, and we also used a binary mask matrix to implement connection control. In general, let the entire Weight Classifier as a whole again, each node in the hidden layer is only connected to the three corresponding nodes in the output layer, and each node in the output layer is connected to only one corresponding hidden layer node. Therefore, the weights between the hidden layer nodes and the input layer nodes represent the preference of the Classifier for features from three sub-models, and the weights between the output layer nodes and hidden layer nodes globally balance the output values of the Classifier to the same level. ![The architecture of one single GO classifier in the weighted classifier.](fbioe-08-00391-g0002){#F2} For all components of the model, we used the Rectified-linear-unit (ReLU) (Glorot et al., [@B14]), which could improve the computational efficiency and retain gradient (Nair and Hinton, [@B34]), as the activation function. Besides, by running specific optimization algorithms to minimize the loss function, the DNN model can be iteratively optimized by updating the weights and biases. Especially, the model is trained using an adaptive optimizer, Adam (Kingma and Ba, [@B25]). 2.4. Evaluate Methods --------------------- We evaluate the performance of the model through three measures, which are F-max, AUPR (area under the precision-recall curve), and AUC (area under the receiver operator characteristics curve), where F-max and AUC are used in the CAFA challenge (Radivojac et al., [@B39]). We use the standard provided by CAFA to calculate F-max and the formulas as follows: F m a x = max t { 2 · p r ( t ) · r c ( t ) p r ( t ) \+ r c ( t ) } where *pr*(*t*) and *rc*(*t*), respectively represent precision and recall of the threshold *t* ∈ \[0, 1\], and can be calculated by the following formulas: p r ( t ) = 1 m ( t ) · ∑ i = 1 m ( t ) p r i ( t ) and r c ( t ) = 1 n · ∑ i = 1 n r c i ( t ) where *m*(*t*) is the number of proteins that annotated with at least one GO term using a threshold *t*, *n* is the total number of proteins in the target data set. *pr*~*i*~(*t*) and *rc*~*i*~(*t*) represent the precision and recall of a specific protein *i* using a threshold *t*, and are calculated by the following formulas: p r i ( t ) = ∑ f I ( f ∈ P i ( t ) ∧ f ∈ T i ) ∑ f I ( f ∈ P i ( t ) ) and r c i ( t ) = ∑ f I ( f ∈ P i ( t ) ∧ f ∈ T i ) ∑ f I ( f ∈ T i ) where *f* is a functional term in the ontology, Function *I*(·) is the standard indicator function. *T*~*i*~ is the set of true labels for protein *i*, and *P*~*i*~(*t*) is the set of predicted labels for protein *i* using a threshold *t*. Once the precision and recall that calculated by different values of t for a particular functional term were determined overall proteins, we could then calculate the AUPR using the trapezoid rule. Compared with AUC, AUPR has a greater penalty for false positives\[6\]. We also calculate the AUC value for each model of the GO sub-ontology, and the calculation formulas are as follows: A U C = ∫ \- ∞ ∞ T P R ( t ) ( \- F P R ( t ) ) d t , T P R ( t ) = T P ( t ) T P ( t ) \+ F N ( t ) and F P R ( t ) = F P ( t ) F P ( t ) \+ T N ( t ) where *TP* is the number of true positives, *FP* is the number of false positives, and *TN* is the number of true negatives, *FN* is the number of false negatives. 2.5. Model Implementation and Computing Environment --------------------------------------------------- We used PyTorch, a Python-based deep learning framework, to implement our model. To speed up the training process, we used a *RHEL* server with four *NVIDIACorporationGM*107*GL* graphics cards installed and total video memory of 32 GB. Under a set of parameters, the whole training time for the most computationally-intensive BP model is \<10 h. In terms of prediction, in the case where the sequence, domain, and PPI input information of the predicted protein has been processed in advance, using an optimized model to predict 1,000 proteins takes about 6 min. 3. Results {#s3} ========== 3.1. Experiment --------------- Owing to the complexity of our model composition and the requirement to determine a large number of hyperparameters, we first pre-trained the three-component sub-models of Sequence, Domain, and PPI Net. We used the GO annotations of proteins as a label and calculated the binary cross-entropy between the predicted values and the actual values, and use this as the loss to back-propagate to update the weights and biases between the nodes connected in the model. We manually adjusted the hyper-parameters, such as the learning rate and batch-size of each module, and selected the optimal model based on the validation loss value using the training set. After adjusting the parameters of the three sub-modules, we used the output of these three fine-tuned models as input to manually adjusted the hyperparameters of the Weighted Classifier, and also select the optimal model based on the validation loss value using the training set. [Tables S1](#SM1){ref-type="supplementary-material"}--[S4](#SM1){ref-type="supplementary-material"} shows the details of the training of different hyperparameters. We used 5-fold cross-validation on the training set to test the performance of the model, and the results are shown in [Table 1](#T1){ref-type="table"}. It is clear that the model has achieved a favorable F-max value for each sub-ontology of GO, which indicates that our method is an
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. "We're clamping our camera mounts between the bed and springs for goodness sake, can't we figure out a better option?" someone exclaimed. The light bulbs flickered on, the gears started to turn and thus a series of Modular products were in motion. It's such a simple idea, we're not sure why we didn't think of it sooner. Just by adding several additional bolt holes to the carriage plate, owners can now design, print and mount a variety of different upgrades to the machine with ease. Made from 6061-T6 Tempered Aluminum Alloy, this carriage is already quite a bit more lightweight than the original plate. This means we have some spare weight to work with, and adding extra parts won't noticeably bog down the bed movements. 3D Printed Example Designs We know there is a lot of creative potential here, but examples can help to showcase ideas and the get the wheels turning. Here are a few example designs we have created to demonstrate the purpose of our Modular products. GoPro Camera Mount & Handle Bar Octoprint has made it simple to use cameras with our 3D printers. Whether we want to record time-lapse videos or live streaming print jobs, it's all possible with a cheap webcam and some plugins. https://www.thingiverse.com/thing:3606128 The Modular Ender 3 Y Carriage Plate features (3) bolt holes on the front left side in a triangle formation, designed to support the extra weight of a camera, plus additional stability during moving shots. The extra (2) bolt holes on the right side are great for lightweight designs, such as the half width handle bar as shown in the photos below. Full-Width Handle Bar Impatient makers rejoice! Inspired by one of our absolute favorite mods, the sleek Ender-3 Bed Handle from LarnOm has been redesigned to fit the Modular Y Carriage. https://www.thingiverse.com/thing:3605862 Don't burn yourself moving the bed while it's still hot, the handle bar stays cool and looks great, making it both a functional and visually pleasing upgrade. Moving Forward In the coming weeks, we plan to roll out these Modular features to our entire product line of Y carriage plates, and soon develop similar capabilities for the hotend carriages as well. For customers who have one of our Y Carriage Plates made prior to these updates, purchased either from us or a Chinese clone, we will release dimensional drawings with measurements to make the holes yourself. Using a drill, M4 cobalt bit and printed schematics, existing plates can be modified to work with Modular bolt-on designs. We're excited to share these changes and show what's possible with our new series of Modular products. Plus, we look forward to what community created content is made possible with more options!Q: auto-refreshing iframe in div still refreshes when DIV is hidden jquery classic asp I have a DIV with an IFRAME that I hide (the div, not the iframe). The iFrame continues to refresh despite being hidden. How do I prevent this? A: $('div').find('iframe').attr('src',''); This stops the iframe loading anything. Post some of your code and explain why the iframe is refreshing. You shouldn't need iframes for most cases, tell us what functionality you're trying to create. Blumenau railway station Blumenau railway station is a railway station situated in the municipality of Rapperswil-Jona in the Swiss canton of St. Gallen. It is located on the Rapperswil to Ziegelbrücke line, and served by an hourly St. Gallen S-Bahn service S6 that operates south-east to Schwanden via Ziegelbrücke. References External links Category:Railway stations in the canton of St. Gallen Category:Buildings and structures in Rapperswil-Jona Category:Swiss Federal Railways stationsQ: CSS has-scrollbar selector? Target elements with visible scrollbars only I want to target elements which have a visible scrollbar using only CSS. Is this possible without javascript? For example, If I have 3 divs styled with overflow-y:auto, How do I change the styles for them only when their scrollbar has appeared? A: CSS does not cover this selection. You need to use JavaScript. The best way to learn dodgeball is to get pelted, which is pretty much what happened to Mookie Betts in center field last night. The Red Sox believe Betts can be a big league center fielder, but the adjustment from second base — where Betts was considered a well-above-average defender — isn’t going to happen overnight. That makes experiences like last night’s 4-3 loss to the Angels so ultimately valuable. Betts was tested three times on balls he’s not necessarily going to see in batting practice or the minors, making one running catch to rob David Freese of a two-run homer in the triangle, missing another Freese drive on an ill-advised dive that resulted in a triple and giving good chase to a ground-rule double in the ninth. “I think this will be great for the long run,” Betts said. “If I’m an outfielder for a long time, I think these things will be good for me.” Start with the play in the second. With Erick Aybar on first, Freese ripped an Allen Webster pitch toward the home bullpen. Betts raced back and made the catch on the run against the short fence in the triangle and then fired to the infield to complete the double play. “When he hit it, my mindset was just go get it, and I happened to go catch it,” Betts said. “I think it was over the fence, but I don’t know.” Freese had better luck with Betts in the fourth, when his sinking liner froze the novice center fielder for a split second. Betts tried to snare it on the dive, but it rolled past him and to the wall. Webster stranded Freese at third, however. “Pretty much just have to get a better read, but (Webster) picked me up, so I’m not worried about it,” Betts said. Betts, who was 1-for-4 with a double, had no chance on Brennan Boesch’s drive deep to center that hopped into the bullpen for a ground-rule double. “He hit it a long way,” Betts said. “I tried to go get it. I couldn’t.” With the Red Sox in 2015 mode, they’ll take nights like last for what they are — learning experiences. “I think every game played in center field is going to be a positive experience for him,” manager John Farrell said. “Given that he’s gone through a positional change this season, particularly against major league hitters and their ability to drive the ball a little bit more consistently here than might be otherwise at the Triple-A level, every game played here is going to be a positive one for him.”Betim Muco Euthanasia - Poem by Betim Muco I took down the old oak treeIn my backyard No more complaints About fallen leaves and branchesBut sometimes when I sit on the stump Smoking my pipe I miss the tree It had become like an ancient grandfather Who allowed me to perform euthanasia.Authorities are urging the public to avoid the area of North Fraser Street and Jessamine Street. Officials with Georgetown County Emergency Management say North Fraser Street is blocked as multiple units are operating in the area.Tag Archive: I.Z.T. Morris By U.S. Sen. John Cornyn Lured by advertisements painting a “land of milk and money” and promises of “free land,” thousands of European families immigrated to the United States in the 1800s. Sadly, overcrowding in northeastern port cities led to unsanitary conditions and diseases that claimed the lives of many overworked parents. This resulted in …In general, the processing of silver halide photographic light-sensitive materials, for example, the processing of a silver halide color photographic light-sensitive material, comprises fundamental processes of color development, desilvering and image stabilization including water washing. In the color development process, the color developing agent reacts with a silver salt to thereby imagewise produce a dye and developed silver. In the desilvering process, the developed silver produced in the color development process is oxidized (bleached) into a silver salt by a bleaching agent having oxidizing action and removed from the light-sensitive layer by a fixing agent which forms soluble silver together with unused silver halide, or the oxidation into a silver salt and the removal thereof are performed in one stage by a bleach-fixing solution. In the image stabilization process, the atmosphere of the image layer is adjusted to attain the stability of the image formed over a long period of time. In the black-and-white development, the fundamental process also comprises development, desilvering and water washing. In respective processing steps, an aqueous solution containing one or more processing chemicals (called a processing solution) is used. Each processing solution is relatively low in the concentration and accordingly, the system where a processing solution usable as it is, is produced by a manufacturer of processing chemicals, transported to a processing laboratory and stored, is generally
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OR, or controlled NOT (CNOT) quantum logic gate. The CNOT gate operates on two qubits $a$ and $b$. See the following diagram: $$\label{Fig3} \xymatrix{ a& \bullet \ar@{-}[l]_{\text{``control''}} \ar@{-}[r] \ar@{-}[d] & a\phantom{\otimes b}\\ b & \bigoplus \ar@{-}[l]_{\text{``target''}} \ar@{-}[r] & a\oplus b }$$ The $\oplus$ symbol in the diagram represents modulo $2$ addition. The CNOT flips the “target” input if its “control” input is $|1\rangle$, and does nothing if it is $|0\rangle$. So, one can clone a basis state, in the two cases: $$\begin{cases} control \, |0\rangle\\ target \, |0\rangle \end{cases} \xrightarrow{XOR} |00\rangle \qquad \begin{cases} control \, |1\rangle\\ target \, |0\rangle \end{cases} \xrightarrow{XOR} |11\rangle$$ (where $|00\rangle$ and $|11\rangle$ stand for the tensor products $|0\rangle\otimes|0\rangle$ and $|1\rangle\otimes|1\rangle$ respectively). We recall that the basis states are, in the corresponding object-language, the atomic formulas $A=|1\rangle$, $A^\perp =|0\rangle$. Then, does not hold in the object-language, as the connective $\otimes$=“$times$” is non- idempotent: $$A\otimes A\neq A \enspace, \qquad A^\perp\otimes A^\perp\neq A^\perp \enspace.$$ But when one tries to clone a superposed state, for example the “cat” state: $$|Q\rangle_{Cat} = \frac{1}{\sqrt{2}} (|0\rangle+|1\rangle)$$ by means of the CNOT, one gets a Bell state, which is maximally entangled: $$\begin{cases} control\, \frac{1}{\sqrt{2}} (|0\rangle+|1\rangle)\\ target |0\rangle \end{cases} \xrightarrow{XOR} \frac{1}{\sqrt{2}} (|00\rangle+|11\rangle)$$ In fact, by the no-cloning theorem, it is forbidden to copy an unknown quantum state: $$\label{eq27} |Q\rangle \nrightarrow |Q\rangle\otimes|Q\rangle$$ Equation holds in the object language as well: $$Q\otimes Q\neq Q$$ Nevertheless, the problem with the connective “times” does appear in the case of basis states, as the corresponding physical link, the tensor product, can form a clone in that case, and this is enough to invalidate the sufficient condition. Let us consider now the sufficient condition in more detail. In the schema of the CNOT, in Diagram, we see that we have cloning for $b = 0$. Let us call cloning the function: $$Clon\colon (a,0)\to (a,a)$$ In the case with $a = 1$: $$Clon\equiv (id, NOT)\colon(1,0)\to(1,1)$$ In the case with $a = 0$: $$Clon\equiv(id,id)\colon (0,0)\to (0,0)$$ Let us consider the case with $a = 1$. See the following diagram $$\label{Fig4} \xymatrix{ L_{m\;\;(1,0)} \ar[dr]^{\;\;\mathrm{Clon}\equiv(\mathrm{id},\mathrm{NOT})}&\\ L_{0\;\;(A,A^\perp)} \ar[u]_{\sigma} \ar[r]^{(F,F')} & L_m\times L_{m\;\;(1,1)} }$$ With: $$Clon\colon L_m\to L_m\times L_m\enspace, \quad Clon\equiv(id,NOT)\equiv \begin{cases} id\colon 1\to 1\\ NOT\colon 0\to1 \end{cases}$$ $$\sigma\colon L_0\to L_m\enspace, \qquad \sigma\colon \begin{cases} A\to 1\\ A^\perp\to 0 \end{cases}$$ $$(F,F')\colon L_0\to L_m\times L_m$$ $$\begin{split} F\colon & A\to 1\\ F'\colon & Aì\perp \stackrel{\perp}{\rightarrow} A \stackrel{F}{\rightarrow}1 \end{split} \quad F'=F\circ \perp$$ $$\label{eq28} \begin{cases} \sigma\circ id =F\\ \sigma\circ NOT = F\circ \perp \end{cases} \Rightarrow F=\sigma$$ The case with $a = 0$ is very similar, and is left as an exercise for the willing reader. Equation says that if it exists a function $Clon$ in the metalanguage, such that the diagram commutes, we recover the usual definition of self-reference, even if the corresponding logical connective in the object-language (in this case “times”) is non-idempotent, and we cannot skip self-referential paradoxes. Then, to be sure that a generalized version of self-reference is present in a given logic, one must check not only that the connective in the object-language is non-idempotent, but also that the corresponding physical link in the metalanguage (in this case the tensor product) does not lead to cloning in some particular case. In a sense, the “reflection” of the metalanguage into the object-language is in general incomplete, as far as self-reference is concerned. This is not the case, however, for the physical link of entanglement, because entangling a basis state with itself is physically meaningless (entanglement is a particular kind of superposition). On the other hand, as we have already seen, entangling an (unknown) quantum state with itself is forbidden by the no-cloning theorem. Then, in the case of entanglement, the reflection between the metalanguage and the object language is complete, and one can adopt the generalized version of self-reference. Our conclusion is that Basic logic is the unique formal language that can reflect a metalanguage, like that of a quantum computer in a entangled state, which is never self-referential (and hence is completely paradox-free). Differently stated, the halting problem in quantum computing appears meaningless once the adequate logical language (Basic logic) is adopted. Appendix A {#appendix-a.unnumbered} ========== In this appendix we give a formal proof of Metatheorem \[meta1\] discussed in Section \[Sec3\]. We try proving $Q_A@Q_A\doteq Q_A$. Let us try first $Q_A@Q_A\vdash Q_A$. There are no rules of Basic logic that we can use in the derivation, which can lead to a proof: $$\frac{}{Q_A@Q_A\vdash Q_A}$$ And, as the cut-elimination theorem holds in Basic logic [@FaSa98], we are sure that there are no other rules leading to a proof. Let us try now the other way around: $Q_A\vdash Q_A@Q_A$. The only rule we can use in the derivation is the $@$-formation rule, and there are no further rules in Basic logic, which would lead to a proof: $$\frac{}{\displaystyle\frac{Q_A\vdash Q_A,Q_A}{Q_A\vdash Q_A@Q_A}\,@-form.}$$ And, again, because of cut-elimination, we are sure that there are no other rules leading to a proof. For the sake of the physical interpretation, we show now that in the case the contraction and weakening rules did hold, the proof would be possible. Let us prove first $Q_A@Q_A\vdash Q_A$. $$\frac{Q_A\vdash Q_A \qquad Q_A\vdash Q_A}{\displaystyle \frac{Q_A@Q_A\vdash Q_A,Q_A}{Q_A@Q_A\vdash Q_A}\,contr.}\,@-\mathrm{exp}l.refl.$$ Let us prove now the other way around $Q_A\vdash Q_A@Q_A$. $$\frac{Q_A\vdash Q_A}{\displaystyle \frac{Q_A\vdash Q_A,Q_A}{Q_A\vdash Q_A@Q_A}\,@-form.}\,weak.$$ It is impossible to prove $Q_A\vdash Q_A @ Q_A$ in Basic logic, because the weakening rule
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Baseball (MLB) club last winter. Although he spent the early season on the bench, the 28-year-old player has been on a roll these days in his MLB debut season, dispelling worries about Kang's success in the world's most competitive baseball league. Former Chicago Cubs first baseman Choi Hee-seop / Korea Times file Batting.379 (33-for-87) with 13 extra-base hits in July, Kang became the second Korean to win the National League (NL) Rookie of the Month, following former Chicago Cubs first baseman Choi Hee-seop who won the honor in April 2003. Kang has collected enough at-bats to qualify for the batting title Tuesday making his time in the batter's box 341 times this season after going 1-for-4 against the St. Louis Cardinals. Among qualified batters in the NL, Kang placed 19th in batting average with.293 and 12th in on-base percentage with.367, establishing himself as a strong candidate for NL Rookie of the Year. As Kang's career continues to thrive, Kang's alma mater Gwangju Jeil High School is getting a lot of attention. Former New York Mets pitcher Seo Jae-weong / AP-Yonhap The school has produced a number of MLB players, including Kang, a native of Gwangju and the school's fourth alumnus playing in the big league. The others include Seo Jae-weong, 38, who had 28 wins and 40 losses while pitching in the MLB for six seasons; former Arizona Diamondback closer Kim Byung-hyun, 36; and Choi, 36, who spent four seasons there as a first baseman. The three former big leaguers now play for the KBO's Gwangju-based Kia Tigers. When Kang joined the Pirates, Kang's alma mater grabbed media attention for producing four big leaguers, surpassing Japan's renowned PL Gakuen High School in Osaka which has produced three — Masumi Kuwata, Kazuo Matsui and Kosuke Fukudome. Gwangju Jeil High School has produced a slew of stars in the KBO such as former Tigers manager Sun Dong-yeol, who was nicknamed "national treasure" for his unhittable pitching; Lee Jong-beom, who won the Korean Series MVP as a rookie in 1993; and Seo Gun-chang, last season's KBO MVP second baseman. Former Boston Red Sox pitcher Kim Byung-hyun / AP-Yonhap Entering the school gate with a low fence on Aug. 11, a wide baseball field covered with artificial grass catches your eye. As the school is on summer vacation, it seemed to be empty except for few vehicles parked in the lot, and due to rain there were no players practicing. Instead, some of the 37 players on the prestigious high school team gathered in small groups in the indoor training center, sweating their way through a practice session. Next to the players was head coach Kim Sun-seob, who waspointing out flaws of the student players. "Though we are pretty busy preparing for next week's Korea Baseball Association President's Flag tournament, we cancelled today's practice session due to rain. But, as you see, some of them came to school for training," Kim said. Gwangju Jeil High School baseball team players celebrate after winning the Bonghwang (Grand Phoenix) Flag High School Tournament hosted by The Hankook Ilbo, a sister paper of The Korea Times, in Dongdaemun Baseball Stadium in Seoul, in this August, 1983, file photo. / Korea Times Last month, the team won its first President's Cup National High School Baseball Tournament in eight years. "As a matter of fact, we have not been in good shape during the last few years. Why? It is because many talented middle school students decide to go to high schools located in Seoul and Gyeonggi Province. Sadly, more and more parents shy away from teams in the provincial areas like us as the big cities have more to offer." In that sense, the head coach, who's also an alumnus of the school, said he is very grateful to Kang for his stunning performance thus far in the United States. "Thanks to Kang, young student players haven't lost their dream that they may play together or against Kang in the MLB in the future. I really appreciatehis moral support," he said. Not only his players but also Kim often gets affected by Kang's every day performances. "It is my routine to check Kang's stats. When he doesn't record a hit or commits an error, I feel down. On the other hand, when he does well in a game, like hitting a home run yesterday, I am in a good mood all day." Kim remembered Kang as a player who, "always practiced more than the rest." "I joined this team as an assistant coach in 2001. I noticed Kang when he was a senior at middle school. After watching him hit breaking balls with precise timing, I thought he had already passed the high school level," Kim said. "As long as I have known him, he always concentrated on polishing up his baseball skills all the time. When he was a freshman, he played as a backup for his seniors. As a sophomore, he played in different positions as a catcher, shortstop, third baseman and pitcher. Frankly, I didn't expect him to become a major leaguer but I was confident he would do well in the KBO." Former Kia Tigers manager Sun Dong-yeol throws a ball in this 1980 file photo. He was a senior member of the Gwangju Jeil High School baseball team at that time. / Korea Times With Kang, the team was the runner-up at the Bonghwang (Grand Phoenix) Flag High School Tournament in 2004 and 2005 and won the Hwanggeum Saja (Golden Lion) Flag High School Tournament in 2005. In the final game of the Hwanggeum Saja tourney, he was the starting and winning pitcher while throwing eight innings and allowing no runs. He also praised Kang's great leadership and personality, saying he always got along with his teammates. "When Kang become a senior, he always tried to take the initiative in every team practice. Also, he knows how to live in harmony, getting along together." ‘Tradition makes them strong' Gwangju Jeil High School's baseball team was established in 1923, three years after the school opened. Since then, it has been atop major baseball tourneys 17 times, emerging as one of the top baseball high schools in the country. On the secret of their strong performance, the head coach stressed that their tradition makes them stronger. "We have been having pretty hard times since 2010 to bring in good players. Nevertheless, we have maintained the top rank because we believe in our tradition and take pride that we are the best high school baseball team in Korea," he said, adding he has been always emphasizing the school's motto — "Fulfilling loyalty and filial piety, inheriting tradition and cultivating ability." Kim Sun-seob, the head coach for the Gwangju Jeil High School baseball team, poses in his office during an interview with The Korea Times in Gwangju, Tuesday. / Korea Times photo by Baek Byung-yeul "At a glance, it doesn't mean anything at all. But when we encounter a hurdle at a crucial phase in the game, we get encouraged by our alumni players. I think that is a huge difference compared to other teams." "Not only Kim Byung-hyun, who has been donating some 10 million won ($8,500) to us so that we can purchase baseball equipment every year, but also Kang donatedlast winter. As you may know, running a baseball team requires money, and those alumni are helping us both financially and morally," he added. Kim also emphasized that the school's well-equipped facilities contribute to the team's success. "As you see, we have quite good facilities so that players can concentrate on practicing baseball skills. Also, as we are situated in the southern part of the Korean Peninsula, we don't have to move to anywhere warm in the winter season," he said. Kang Jung-ho, right, a catcher for the Gwangju Jeil High School baseball team, attempts a force out during his team's game against Jeju High School in the Bonghwang (Grand Phoenix) Flag High School Tournament in Dongdaemun Baseball Stadium in Seoul in this August 9, 2005, file photo. / Korea Times "I joined the Ssangbangwool Raiders in 1996 after graduating university as an infielder and retired in 2000 as I suffered elbow injuries. After I began coaching this team, I studied hard about how to prevent possible injuries. I have provided the students with training programs that will strengthen the players rather than focus on baseball technique," he said. Park Ju-hong, a freshman pitcher who recorded a win in the final game of the last month's President's Cup against the Sungnam High School, said choosing Gwangju Jeil High School was the best choice he made. "After I came to this high school, my baseball performance improved a lot. Under the guidance of the head coach, I focus on physical and technical training. Someday I would like to pitch against Kang on the MLB stage and strike him out," he said. Lego Antikythera
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channels, which contribute to the nuclear membrane potential, may be important in balancing the charge carried by the movement of macromolecules in and out of the nucleus.Saturday, August 16, 2008 Writer's Block #4 "Describe the most meaningful and/or important gift you've ever received. What does it reveal about your relationship to the giver?" There are several of those. Several years ago for my birthday, my parents drove up to Birmingham to surprise me with a beautiful cedar chest that my Dad had been working on for months. The wood came from a tree that had been in Papaw's yard for years. A tree that Pete & I and our cousins used to climb when we were kids. It was cut down a long time ago and Dad got the wood from it. I had been telling him for years that I wanted a cedar chest. I don't know, he may have been planning on building it long before I thought of it. The day of my birthday, I was nearly ready for work when I texted Mom to tell her I was awake. Funny, I was a little upset because they hadn't called yet. (Of course, Wes knew all about the surprise). Mom called me back and skirted around the issue until I finally figured out that they were on their way. What I didn't know is that they were bringing the cedar chest with them. I was completely surprised. Mom & Dad both wrote a note and had it inside. They both made me cry. I now have the cedar chest in my living room which is where it will always stay, prominently displayed for everyone who comes by to see. I have a lot of memories inside it, from our wedding & honeymoon pictures, cards, scrapbooks, some things that belonged to Mamaw, and many, many other memories. Of course, I'll never part with it. It'll be passed down through the generations. Lazy and Phoebe are gifts that have meant the world to me over the years. When I was in Junior High, my dad came home one day and told me to go outside and look in his truck. I didn't know what this meant or why and I was a little scared. I walked out in the dark and looked in the passengers side window and found a pair of gold eyes staring back at me. At first I was startled. I quickly realized that looking back at me was a cat. I had had a cat before. Her name was Ms. Kitty (I know, I was 9). She had gotten run over. The cat in the truck would turn out to be Lazy, my first "child". She slept with me nearly every night for the next ten years. She was the perfect pet. She kept me sane during the grueling adolescent and High School years. When I left home, I left without her. Mom & Dad took care of her. I wanted to take her with me, but she loved to go outside and would have been miserable stuck inside an apartment and I wouldn't want her to be in that environment. She spent her days chasing birds, eating them and terrorizing the dog, chickens, etc. One day Dad had killed a chicken and Lazy snuck up behind us while he was preparing to clean it and attempted to drag it off. That chicken was bigger than she was and she was dragging it away. I don't know how old she was when she died, but I had had her for about 14 years. She died two years ago. Phoebe was a pleasant surprise. Wes gave her to me for Christmas in 2006. We were living in Birmingham. I was in Charleston for my job interview and Wes picked me up from the airport. When we got home, he wouldn't let me go inside the apartment because he had to "hide" my Christmas present that he bought while I was gone. I had to wait on the stairs. I was tired and irritable because one of my flights was delayed. When he finally told me I could come in, he was standing there with this little ball of fur in his arms. My heart sank! I was in tears within seconds. She was so sweet and innocent. She took to me quickly and is now our "second" child. Although she looks similar to Lazy, she has a completely different personality. Phebs is very playful. She has her toys that she loves to play with, but her favorite is what we call "Yellow thing." (It's a yellow feather on a stick) We regularly get it out and play with her. She loves to chase it around in circles until she's panting and her little heart is racing. It's good exercise I guess. She knows where we keep it and she will stand at the closet door and cry until we get it out. (SPOILED!!) She also fetches. We have several little foam balls laying all over the house. She'll occasionally bring one to us and we'll throw it down the hall a few times for her. She will follow us around in the mornings to remind us to open the window shades so she can watch the birds. I know I've received countles gifts that are priceless to me. Memories are priceless. I wouldn't be able to write about all of them because I receive gifts every day. There's nothing like being able to step outside in the sunshine and take a deep breath. Waking up next to the best husband in the world. The love of family surrounding you. These are all priceless gifts from God. No comments: Visit me on Facebook... About Me I'm still learning things about myself every day. I'm a 32 year old running addict with a great husband, a loving and supportive family, and a job I'm satisfied, but bored with. I'm looking for something new that will challenge me. Currently returning to college for Exercise Science. Running makes me happy. One day I'll be randomly given bib #47 in a race. That would be sweet!At the tender age of eight (56 in dog years), Strongheart is technically the youngest actor to receive a walk of fame star. Unlike Kim K., Strongheart has never been divorced or at the center of a sex scandal, (was he even neutered or did he just let it all hang out?), but he did change his name. Born Etzel von Oerlingen in Wroclaw, Poland, the canine actor who appeared in White Fang in 1925 was originally trained in kennels as a police dog and has an upstanding record of service in the German Red Cross in World War I. He is trained to tear clothing of a person, scare intruders and even kill. Giving a star to a trained killer seems a little wrong. Also, Strongheart is a dog. A dog has a star, but not Kim Kardashian.Live It Out Live It Out is the second album released by the Canadian indie rock band Metric. It was released in September 27, 2005, on Last Gang Records. The album has sold 45,000 copies in the US, and went platinum in Canada selling 100,000 units. Live It Out was shortlisted for the 2006 Polaris Music Prize and nominated for "Alternative Album of the Year" at Juno Awards 2006. The album was also chosen as one of Amazon.com's Top 100 Editor's Picks of 2005 and the 38th best album of 2006 by NME. There were three singles (and videos) released from the album: "Monster Hospital", "Poster of a Girl" and "Empty". "Handshakes" was a radio promo, released only in Canada. Track listing Personnel Emily Haines – vocals, synthesizers James Shaw – guitar, vocals, producer Joshua Winstead – bass guitar Joules Scott-Key – drums Charts References Category:2005 albums Category:Metric (band) albums Category:Last Gang Records albums Category:Albums recorded at Metalworks StudiosUltrasound assessment of common bile duct diameter in Tikur Anbessa Hospital, Addis Ababa, Ethiopia. The diameter of common bile duct is one of the critical issues that has to be addressed in diagnosing and treating hepatobilary diseases. Thus measurement of common bile duct diameter is an important component of the evaluation of biliary system as the size of common bile duct is a predictor of biliary obstruction. As a dilated common bile duct distinguishes obstructive from non obstructive causes of jaundice, accurate standards for normal measurements must be available. There is no study addressing the diameter of common bile duct diameter among Ethiopians. To assess the normal common bile duct diameter among Ethiopians and to identify factors associated with common bile duct diameter. A cross-sectional descriptive study. Tikur Anbessa Teaching Hospital, Addis Ababa, Ethiopia from April, 2001 to September, 2002. A total of 293 adult patients of which 160 females and 133 males who were to undergo abdominal ultrasound were put under the study. All patients had fasted for longer than six hours. Patients with known biliary, pancreatic disease or surgery were not included in the study. The transverse and anteroposterior diameter of the common bite duct were measured just caudal to the level of portahepatis. The mean diameter of the common bile duct diameter was found to be 3.9 mm; measured diameter ranged from 2.1 to 6mm. There was also a positive correlation between the common bile duct diameter with age and weight. No significant difference was noted between the two sexes and common bile duct diameter. No association was observed with height and common bile duct diameter. The study showed the mean common bile duct diameter to be 3.9 mm and the diameter of the common bile duct was observed to increase with increasing of age and weight. The normal common bile duct
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015^\#^ Diastolic blood pressure 80.10 ± 11.53 79.13 ± 11.93 81.13 ± 11.40 0.067 Fasting blood glucose (mM) 9.97 ± 6.44 8.51 ± 3.34 9.03 ± 3.98 0.357 Total cholesterol (mM) 4.40 ± 1.04 4.41 ± 1.21 4.60 ± 1.18 0.070 Triglyceride (mM) 1.61 ± 1.34 1.72 ± 1.44 1.59 ± 1.10 0.527 High-density lipoprotein (mM) 1.17 ± 0.33 1.18 ± 0.37 1.18 ± 0.40 0.791 ---------------------------------------------------------------------------------------------- *Note:* Values are presented as mean ± SD except for the gender. *P* values were determined using a one-way analysis of variance except Chi-square analysis for the gender. *P* value with multivariate logistic regression analysis adjusted for age, gender, and body mass index is indicated by ^\#^. Comparison between CC genotype *vs.* CT + TT genotypes was performed using recessive model. The blood pressure data were missing for one patient with CC genotype (*n* = 273). T2DM, type 2 diabetes mellitus. ###### Association of genotypes with risk of hypertension in Chinese Han T2DM patients **Blood pressure** **Genotype, number (%)** ***P* value** -------------------- -------------------------- --------------- ------------- ------- Systolic  \<140 mmHg 18 (46.15) 103 (47.47) 105 (38.46) 0.037  ⩾140 mmHg 21 (53.85) 114 (52.53) 168 (61.54) 

 Diastolic  \<90 mmHg 30 (76.92) 174 (80.18) 209 (75.56) 0.340  ⩾90 mmHg 9 (23.08) 43 (19.82) 64 (23.44) *Note: P* values were determined using Chi-square analysis. Multivariate logistic regression analysis was performed after adjusted for age, gender, and body mass index. The comparison between CC genotype *vs.* CT + TT genotypes was performed using recessive model. ###### Association of genotypes with risk of diabetic complications in Chinese Han T2DM patients **Complication** **Genotype, number (%)** ***P* value** **OR (95% CI)^a^** **OR (95% CI)^c^** ----------------------- -------------------------- --------------- -------------------- -------------------- ------ ------ ------------------- ------------------- Macrovascular disease 15 (38.46) 105 (48.39) 147 (53.65) 0.06 0.16 0.05 1.29 (0.99--1.69) 2.10 (1.00--4.45) Diabetic retinopathy 17 (43.59) 101 (46.54) 148 (54.01) 0.07 0.18 0.21 1.28 (0.98--1.67) 1.55 (0.78--3.08) Diabetic nephropathy 7 (17.95) 63 (29.03) 77 (28.10) 0.46 0.36 0.17 1.12 (0.83--1.52) 1.85 (0.77--4.43) Diabetic neuropathy 24 (61.54) 108 (49.77) 149 (54.38) 0.96 0.32 0.40 1.01 (0.77--1.32) 0.74 (0.37--1.48) *Note: P* values for allele frequency (^a^) and genotype distribution (^b^) were determined using Chi-square test. Multivariate logistic regression analysis was performed for CC genotype *vs.* TT genotype after adjusted for age, gender, and body mass index (^c^). T2DM, type 2 diabetes mellitus. [^1]: ORCID: 0000-0001-7913-2070. [^2]: ORCID: 0000-0003-0260-2593. [^3]: ORCID: 0000-0002-7230-448X. [^4]: ORCID: 0000-0002-0093-0190. [^5]: ORCID: 0000-0002-0736-1920. 1978–79 Alpha Ethniki Alpha Ethniki 1978-79 complete season League standings Match table Top goalscorers References Greek Wikipedia Official Greek FA Site Greek SuperLeague official Site SuperLeague Statistics Category:Alpha Ethniki seasons Greece Category:1978–79 in Greek footballNow, we can add an entry to this growing list. At least in mice, gut bacteria can influence whether cancer treatments work. Working independently, two teams of scientists showed that three cancer treatments rely on gut bacteria to mobilise the immune system and kill tumour cells—not just in the gut, but also in the blood (lymphomas) and skin (melanomas). Remove the bacteria with antibiotics, and you also neuter the drugs. “It was a surprise,” says Romina Goldszmid from the National Cancer Institute, who led one of the studies. “Nobody would ever have thought we should worry about gut bacteria when thinking about treating cancer.” The first team, led by Goldszmid and Giorgio Trinchieri, treated tumour-ridden mice with immunotherapy—a cocktail of substances that stimulates the immune system to attack cancer cells. The cocktail shrank the tumours, and prolonged the rodents’ lives. Two months later, around 70 percent of them were still alive. But if the mice drank a cocktail of antibiotics a few weeks earlier, the immunotherapy no longer worked. It failed to keep the tumours in check, and at the two-month mark, only 20 percent of the mice were alive. The team showed that the gut bacteria stimulate immune cells that live inside the tumour, priming them to respond to immunotherapy. Think of the bacteria as cocking the pistol, while the immunotherapy pulls the trigger. Without that first step, nothing dies. Goldszmid and Trinchieri’s team also tested a different cancer drug called oxaliplatin, which is used to treat cancers of the bowel, stomach and gullet. It works by damaging DNA, which supposedly prompts cancer cells to release a powderkeg of oxygen molecules. These are so chemically reactive that they wreak fatal havoc inside the tumours. But the team found that the cancer cells themselves only produce a fraction of these killer molecules. The rest come from the immune cells that live among them. And once again, these cells only did their job if they primed for action beforehand by the gut bacteria. When the team killed the bacteria with antibiotics, oxaliplatin lost its sting. Meanwhile, the second group led by Laurence Zitvogel from the Gustave Roussy Institute in France tested a drug called cyclophosphamide or CTX, which is used to treat breast cancer, lung cancer, and more. It seems to recruit two types of immune cells called TH1 and TH17 cells which cooperate to attack the tumours. Scientists have known about this immune response for decades, but Zitvogel’s team found that it happens for unexpected reasons. Cyclophosphamide damages the layer of mucus that coats the intestines, allowing bacteria that live in the mucus to move deeper into the gut. Some of them travel into the spleen and the lymph nodes, where they nudge the resident immune cells into becoming TH1 and TH17 cells. So, cyclophosphamide does its thing by making the gut leaky, and allowing bacteria to migrate out of it! And once again, when the team killed the bacteria with antibiotics, the cancer-killing immune cells weren’t recruited, and the drug became drastically less effective. What does this mean for cancer patients? “We have to be extremely cautious,” says Goldszmid. “These were mouse studies. It is now absolutely important that these be corroborated in careful human studies.” Even if they are successful, putting this knowledge to practical use will be very hard. For example, doctors often treat cancer patients with a wide range of other antibiotics. This helps to deal with existing infections and to prevent new ones, especially after treatments like radiotherapy that can suppress the immune system. Based on the new studies, you could argue that these antibiotic assaults make matters worse, but what’s the alternative? “You don’t want to stop giving antibiotics to people who are immune-suppressed,” says Goldszmid. Instead, doctors might give their patients probiotics to supplement their impoverished guts with the right bacteria. But, which bacteria? In Goldszmid and Trinchieri’s experiments, mice with lots of Lactobacillus in their guts responded poorly to immunotherapy. But Zitvogel’s team found that two species—
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I found." O'Malley pulls the door open. Inside is a small room with three waist-high white pedestals, the same kind that were in that spherical room where I first saw Brewer and Matilda—the place she called the Crystal Ball. I instantly want to knock the pedestals over, smash them...if Matilda's face appears, or Brewer's, I will do just that. We need to leave the Grownups behind, forever. O'Malley steps to the middle pedestal. Sparkles flare up above it, just like they did in the Crystal Ball, but instead of Brewer's red-eyed face, I see the words GAMBIT PRIV, and below them, small images: O'Malley's face, and Aramovsky's, and...mine? I've seen myself only once, a brief reflection in the shuttle's polished hull. That reflection showed dirt and blood, dust and damage, all the bruises I suffered in our fight to escape. Messy hair, split lip, black eye, scratches from my fight in the woods and being dragged through the thicket. The tiny face above the pedestal, though, has no marks. No cuts, no blood. It's me, but older. The last of the girl I am is gone—what I see is all _woman,_ striking and confident. O'Malley's and Aramovsky's images look older, too. So... _manly_. The image makes O'Malley look even more handsome than he already is. "I don't understand," I say. "Is that us?" "Maybe it's how the Grownups thought we would look in a few years. Or how our progenitors looked when they first designed us, set us to growing in the coffins?" It's so strange to look at an older version of myself. Glossy black hair hangs in luxurious curls rather than being pulled back into my severe braid. Smooth light-brown skin. Lips a dark shade of red. Eyelids painted pink. But that face...it's not _real_. It is the face of a doll, dressed up the way its owner wanted. "You're beautiful," O'Malley says. The word makes my breath catch. I glance at him—he's not looking at me, he's looking at the image. That isn't me, it's _Matilda,_ how she would look if she wiped me from existence. "A picture of me is beautiful, but the real thing isn't?" His eyes flick to me, widen. "Well, no...that's not what I'm saying." "That's exactly what you said." He shakes his head. "You're beautiful, too, Em. When those bruises heal, you'll look amazing." But I don't look amazing now. I don't want to talk about it anymore, so I change the subject. "Those words, _gambit priv_. What do they mean?" "No idea. When I walked up to the pedestal, this is what appeared." He reaches out and touches the image of my face. Next to it appear two symbols in gold: circle-star, circle-cross. Two symbols in silver: the gear and the half-circle. And one symbol in white: the double-ring. There are no plain circle symbols at all—no _empties_. "I think gold means you can access any door with those symbols," O'Malley says. "Silver might mean you can access _some_ doors with that symbol." "And white means I can't access those areas at all?" He nods. "I think so." I touch the floating picture of O'Malley's face. The symbols and colors are the same as mine, except for the gear, which for him is white. He can't access anything with a double-ring or a gear. Then I touch Aramovsky's face: gold for the double-ring, white for everything else. Why just our three faces? No image of Spingate or Gaston. The shuttle will fly for Gaston, but has areas he can't access? Why? When Grownup Aramovsky died, he was with Matilda. Did they have some connection? And what about Grownup O'Malley—is that monster still alive, too? The Grownups kept things from each other. They fought, they murdered, they kept themselves divided. I don't want to be anything like them. "Can we change this, so everyone has access to everything?" "I tried," O'Malley says. "It won't let me do much of anything." He faces the pedestals, licks his lips. He's acting so strange. What has him so anxious? "Shuttle, where are we?" he asks. A soft voice purrs from the walls. _"Omeyocan."_ Black spots form above all three pedestals. The spots fuzz with sparkles of every possible color, then solidify. I'm looking at a planet: blue, green and brown. It spins slowly. It is exactly what I saw up on the _Xolotl_. "Shuttle," he says, "I need to change access privileges." _"Chancellor, O'Malley, Kevin Patrick, speak the access code to continue."_ His first name is _Kevin_? I like that name. But I like _O'Malley_ more. "I think some info is available to anyone," O'Malley says. "But most of the questions I ask, it wants a code that I don't know." The shuttle obviously recognizes him. It must think he is the Grownup O'Malley, after an overwrite. Maybe it will make the same mistake with me. On the _Xolotl,_ Matilda seemed to be in charge. I face the pedestals. "Shuttle, do you know who I am?" _"Savage, Matilda Jean, Empress."_ Empress? O'Malley laughs. He rolls his eyes, smiling. "Your _Highness_. Should I bow?" I punch his shoulder. "Shuttle," I say, "what do our symbols mean?" _"Speak the access code to continue."_ "If I'm the _empress,_ I don't need a code. What do our symbols mean? What is this city?" _"Gambit-level information requires verbal confirmation of access code, Empress_. _Speak the access code to continue."_ "Told you," O'Malley says. "What else is on this deck?" "Nothing as far as I can tell. I think the rest of this deck's space has machinery...maybe to take care of what's below us, on Deck Four." His voice wavers when he speaks. He sounds anxious, and perhaps a little afraid. Whatever he's afraid of, it's down there. "All right," I say. "Show me." His lips press into a flat line. "Come on." I follow him down to the last deck. There is a wheel-door, just like the others, but this one has a circle-cross in the hub. "I was able to open it," he says. "According to the symbols in the pedestal room, I think you can, too." He waits for me to do so. Now I'm a little afraid, as if his anxiety is contagious. I grip the wheel. It spins easily. I pull the door open and step through. I am looking into a long space undivided by walls or doors. There is nothing here, in fact, save for what lies on the floor. Two long columns of brown coffins, clean and shining, covered in carvings of jaguars, pyramids and suns. O'Malley and I return to the top deck. People are playing, talking, even napping inside the white coffins. I catch Bishop's eye, tilt my head toward the pilothouse. He nods, picks up his axe and follows us. Before we reach the pilothouse door, the wheel spins. Gaston and Spingate step out. They don't look as rested as I'd hoped, but they look happy, and that's something. "Back inside," I say. "I need to talk to you both." We enter. Bishop starts to swing the door shut behind us, but it stops halfway: smiling Aramovsky is blocking it with his body. "Are we making plans?" he says. "Good. We need to discuss the spiritual needs of the people." Bishop glances at me, but when he does, skinny Aramovsky slides through the door and into the room. It would have been one thing to say he couldn't come in—it's entirely another to make him leave. Which, of course, Aramovsky knows. Bishop shuts the door. The first time I entered the pilothouse, the walls were black. Now it's as if there are no walls at all. It looks like I'm standing in the middle of the clearing that ends in a tall, circular wall of piled vines. I see
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separate column, and the diminished quantity of "tar" remaining can be burned or otherwise utilized. 126 Ill. App.3d 74 (1984) 466 N.E.2d 1304 JOHN LUETJE, Plaintiff-Appellant, v. OTTO CORSINI et al., Defendants-Appellees. No. 83-2270. Illinois Appellate Court — First District (5th Division). Opinion filed July 20, 1984. Goldstine and Broida, Ltd., of Summit (Ronald J. Broida and Kenneth J. Nemec, Jr., of counsel), for appellant. Stern, Rotheiser & Dupree and Lord, Bissell & Brook, both of Chicago (James M. Dupree, Hugh C. Griffin, and William D. Frazier, of counsel), for appellees. Order affirmed. JUSTICE SULLIVAN delivered the opinion of the court: This is an appeal from an order granting defendants' motion to dismiss plaintiff's amended complaint seeking damages for personal injuries. In the complaint, plaintiff — a volunteer firefighter for the village of Summit — alleged that he was injured while fighting a fire in *75 defendants' building when the chimney collapsed and fell on him, and that the fire, the chimney collapse, and consequently his injuries proximately resulted from numerous acts of wilful and wanton misconduct by defendants which essentially relate to their failure (a) to maintain the premises, including the chimney, in safe condition and (b) to comply with applicable fire prevention and building codes and ordinances, despite repeated demands by State and village officials that they do so. Defendants' motion to dismiss the complaint for failure to state a cause of action was granted, and this appeal followed. OPINION In support of his contention that the trial court erred in its ruling, plaintiff relies primarily on Dini v. Naiditch (1960), 20 Ill.2d 406, 170 N.E.2d 881. In Dini, one firefighter was killed and another was seriously injured when, as they were ascending a defectively constructed staircase to reach and extinguish a fire on the upper floors of a building, the entire staircase suddenly collapsed and fell on them. In holding that the judgment n.o.v. for defendants was improperly entered, the Dini court, after stating that "the common law rule labeling firemen as licensees was an illogical anachronism," held that "an action should lie against a landowner for failure to exercise reasonable care in the maintenance of his property resulting in the injury or death of a fireman rightfully on the premises, fighting the fire at a place where he might reasonably be expected to be." (Dini v. Naiditch (1960), 20 Ill.2d 406, 416-17, 170 N.E.2d 881, 885-86.) Thus, as plaintiff correctly states, the court in Dini specifically rejected the common law classification of firefighters as licensees to whom the landowner owed no greater duty than to refrain from wilful or intentional injury and imposed upon landowners or occupiers a duty equivalent to that owed to invitees, i.e., to exercise reasonable care to keep their premises in safe condition. We note, however, that Dini did not involve allegations of wilful and wanton misconduct, nor have the subsequent cases which have examined the scope of the Dini decision. These cases, while holding that landowners are required to exercise reasonable care to prevent injury to firefighters from causes unrelated to the fire, have also held that no such duty is owed to a firefighter where the act or omission complained of was a cause of the fire. In Netherton v. Arends (1967), 81 Ill. App.2d 391, 225 N.E.2d 143, plaintiff sought damages for injuries suffered from inhaling smoke and noxious gases while fighting a fire allegedly caused by defendant's negligence in storing hazardous, combustible materials on *76 his property. In affirming the judgment for defendant, the Netherton court discussed Dini and the cases cited therein and noted that in each instance where liability had been imposed the act or omission causing the fire was not the act or omission causing the injury. The court then stated, "We do not think that Dini holds or intended to hold that negligently creating a fire hazard or causing a fire ipso facto creates a liability upon an owner * * * to an invitee fireman for injuries received in the performance of his duties" (Emphasis added.) (Netherton v. Arends (1967), 81 Ill. App.2d 391, 395, 225 N.E.2d 143, 145), reasoning that since negligence is frequently the cause of the fire necessitating the firefighter's presence on the premises, the duty imposed upon the landowner by Dini is to refrain from negligently injuring him after he is on the property. The court further noted that absent a charge that the smoke or gases produced were in some way different than those which might be created by any other fire, the hazards which plaintiff faced were merely incidental to his occupation, and concluded that the duty of a landowner to a firefighter is to avoid creating, or to warn him of, known latent defects in the premises which with a reasonable degree of foreseeability might cause him injury. A similar situation was presented in Horcher v. Guerin (1968), 94 Ill. App.2d 244, 236 N.E.2d 576, where a firefighter brought an action against the owner of a vacant building who had failed to comply with city directives that the building — which was in dangerous and unsafe condition in violation of various city ordinances — either be repaired or demolished. While fighting a fire thereat, a particle of glass from an inoperative window which had to be broken to ventilate the building struck plaintiff, causing him to lose his sight in one eye. In affirming the judgment n.o.v. for defendant, the Horcher court rejected plaintiff's contention that, under Dini, a landowner may be held liable to a firefighter for negligence in causing the fire, and noted, as did the Netherton court, that because most fires can be attributed to some form of negligence, the hazards resulting therefrom are reasonable risks assumed by those in the occupation of fighting fires and are beyond the scope of the duty owed by a landowner to remove hidden or unusual dangers on the premises or to give adequate warning thereof. As to the alleged ordinance violations, including cracked walls, improper space heaters, a defective electrical system, and the general state of disrepair, the court observed that most of these violations related only to possible negligent causation of the fire for which there is no cause of action, and that even if plaintiff came within the purview of the ordinance prohibiting obstruction of *77 windows, he had failed to establish a causal connection between the negligence in permitting the windows to be stuck and his injury, which resulted from breaking the window to accomplish full ventilation of the building. Thereafter, in Erickson v. Toledo, Peoria & Western R.R. (1974), 21 Ill. App.3d 546, 315 N.E.2d 912, this court affirmed the order of the trial court dismissing plaintiff's complaint for failure to state a cause of action in a case involving injuries sustained by a firefighter when one of the defendant's derailed tank cars containing propane gas exploded, ruling that the allegations therein related to acts which either created the fire or contributed to its severity. Noting that liability in the Dini case was predicated upon a combination of factors, the foremost of which was the collapse of an inherently defective stairway — a condition unrelated to the fire — we followed the reasoning in Horcher v. Guerin (1968), 94 Ill. App.2d 244, 236 N.E.2d 576, and Netherton v. Arends (1967), 81 Ill. App.2d 391, 225 N.E.2d 143, and held that liability can be imposed only where the firefighter is exposed to undue risks beyond those inevitably associated with fighting a fire. Whatever uncertainty may have existed as to whether these cases correctly interpreted Dini was dispelled by Washington v. Atlantic Richfield Co. (1976), 66 Ill.2d 103, 361 N.E.2d 282, where our supreme court was again presented with the issue of a landowner's liability to a firefighter injured in the performance of his duties, and took the occasion to discuss the appellate decisions cited above and to clarify the scope of the duty imposed upon landowners by Dini. In Washington, two firefighters were seriously burned while attempting to extinguish a fire in and around a car parked in defendant's filling station. The fire began when the driver of the car threw a match into a pool of gasoline that the station's attendant had allowed to overflow from a malfunctioning gasoline pump. Plaintiffs charged defendants with having caused their injuries by using a defective pump, permitting the car's tank to overflow and allowing the driver of the car to smoke on the premises. In rejecting plaintiffs' contentions that, under Dini, defendants were liable for the injuries resulting from these acts and that the appellate decisions which we have discussed above constituted "unwarranted deviations" from Dini, the supreme court noted that the principles applied in those cases were consistent with and had been inferentially approved by its holding in Fancil v. Q.S.E. Foods, Inc. (1975), 60 Ill.2d 552, 328 N.E.2d 538, where recovery for the death of a policeman who was fatally shot in an ambush while making a routine security check of defendant's unlighted premises was denied on the ground that the risk to which the *78 decedent had been subjected was "inherent in the occupation" and thus not unreasonable. Applying
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the expense of customers, investors, and the planet alike. 3. A commitment to “private governance.” In the early 2000s, AstraZeneca recognized that if the company didn’t establish wastewater discharge limits for the minute quantities of waste pharmaceuticals associated with their manufacturing activities, no one would. It was the right thing to do and, before long, the entire industry confronted the “pharmaceuticals in the environment” challenge collectively. In the IT sector, similar initiatives are happening in the areas of AI, data security, and data center energy efficiency. Governments are often unwilling, unable, or otherwise poorly positioned to steer corporate behavior that, if managed irresponsibly, place people, the planet, or our social institutions at risk. Stakeholders must be able to trust companies to step up and lead the way through product stewardship, self-regulation, and transparent, coordinated action. 4. Inspired and inspiring leaders who get the "WHY." A 2015 McKinsey study concluded that 30% of a company’s value is at stake in its relationship with society. Certain elements of that relationship are universal: the depth of our respect for the rule of law, the way we treat people, and the extent to which we help to protect the planet. These principles must be embedded in the business’ DNA and manifest in the words and actions of the CEO, the design of the corporate strategy, and the strength of the organization’s programs. As Simon Sinek would say, “it starts with why,” but the “what” and how” are also essential. Business leaders—from the board room to the C suite to the shop floor—must understand, manage, and communicate what’s at stake in that company-society relationship every day. 5. Trusted and collaborative “Second Lines of Defense.” People come and go, restructuring is a constant, and organizational designs swing with the pendulum. What doesn’t change, however, is the value of trusted, experienced, and collaborative teams of advisors, partners, and subject matter experts who help set the tone, build the programs, develop the targets and metrics, provide the assurance, and otherwise help the company deliver. Whether organized as stand-alone organizations or integrated Sustainability and ESG teams, these "second line of defense teams" must be well-positioned to identify the emerging threats and opportunities, hold up the mirror on performance, help leaders “embrace the gray," and ensure that the commitments are built, embedded, and delivered. They are the chemists, the engineers, the accountants and... the “architects!” But even amateur architects understand that the best designs rely upon the strength of the earth beneath them, and, in the case of the playing field upon which companies currently operate and compete, some serious groundskeeping is in order. This is because despite the best intentions of companies pursuing “sustainability” and the growth of the ESG movement, at a macro level, our current capital markets appear incapable of promoting and supporting the commitments, investments, and deliverables that we need to protect our collective future. While a recent former corporate lawyer’s declaration that business executives are “legally obligated to act like sociopaths” certainly overstates the problem, day-to-day company decisions on what priorities to set, what goals to pursue, and what it means to be truly sustainable and "deserving" are often undermined by the market’s obsession with quarterly reports, its failure to incorporate negative externalities, and its short-sighted and outdated fixation “shareholder value maximization.” As one writer has cleverly put it, we are living in an era of “Greenwish.” So, while the market's garden may remain aesthetically pleasing, the hidden weeds are invasive and potentially destructive. The Cambridge Institute for Sustainability Leadership (CISL) has produced what I’d consider the most logical plan for systemic change. Titled Rewiring the Economy: Ten Tasks, Ten Years, CISL identifies a set of 10 interconnected tasks for the business, government, and financial sectors to pursue in an effort to “enable fundamental change in how the global economy is harnessed for social and environmental good.” Some other compatible ideas are also emerging, including the concept of the “Social Board”; amendments to SEC disclosure rules that would compel companies to disclose ESG-related risks as an expansion of the current “materiality” disclosure framework; and requirements for companies to “adopt a binding set of ethical rules” that would address “the key ethical dimensions of corporate life,” including their relationships with employees, customers, the environment, and future generations. And of course, the Business Roundtable has just issued a new Statement on the Purpose of Corporations signed by 181 CEOs who “commit to lead their companies for the benefit of all stakeholders.” Reactions have ranged from “halleluiah” to “it’s nothing new—they’re just preempting Elizabeth Warren.” I’ll hedge for now and see it as a positive and timely development that can at a minimum provide companies with some additional cover to embed sustainability into their DNA and raise the corporate performance bar across the SDG. After all, a rising tide lifts all boats; we just need that tide to be real and not a mirage. One newly formed entity, The Shareholder Commons (TSC), is particularly well-positioned to help companies and their investors “walk the talk.” TSC is the brainchild of Rick Alexander, a former Head of Legal Policy for B Lab and Managing Partner of the Morris Nichols law firm in Wilmington, Delaware. The big idea behind TSC is the establishment of corporate sustainability “guardrails” or “tickets to the game” that would be established in collaboration with the private sector and enforced by institutional investors through engagement and, as necessary, shareholder proposals and proxy voting. Examples could include science-based environmental improvement targets; accounting for carbon emissions; executive pay linked to ESG performance; limits on tax avoidance schemes; and other SDG-aligned minimum performance expectation. This platform would raise the sustainability bar across the board, for the benefit of the planet, society, and the “Universal Owners” who collectively have the most to gain and lose from the way in which environmental and social systems and other externalities are managed over time. I am proud to be serving as an advisor to TSC as the initiative progresses. In closing, I’ll move from the cathedral story to an analogous one involving a visit to NASA by President John F. Kennedy. While touring the facility, JFK asks a janitor what he did for the agency. “I’m helping to put a man on the moon,” he answered! As we commemorate the 50th anniversary of the moon landing, we’re faced with what may be an even more daunting challenge: preserving our planet and social and economic systems in ways that will make our progeny proud. It will take engineers, lawyers, chemists, entrepreneurs, computer scientists, and folks of countless other “occupations” to meet this challenge. It will also need a private sector—incentivized and emboldened by our capital markets—that is committed to converting the vision, creativity, and determination of these experts into successful “moonshots.” This is what will build the foundations of sustainability, make our children proud, and, yes, continue to render our formal occupations moot. So, the next time I’m asked the “what’s your occupation” question, I’m going to resist the “recovering lawyer” response and answer something like: “aspiring mason!” How about you?Q: Give renderObj = IMAGE a class I want to use a lazy-loader for my images. Therefore I found a JS which seems pretty comfortable. Nevertheless, my images need a class="lazy" so that the JS knows which images it should affect. The problem is, that I'm using a dynamically generated page with images which are stored in the media relation of each page. Idk if you guys understood what i meant :D But anyway, that's not the point. The point is, I need a way to give the rendered images a class by TypoScript. I'm looking for something like this: [...] renderObj = IMAGE renderObj { file.import.data = file:current:publicUrl altText.data = file:current:title addClass = lazy } [...] A: You can use params for this: [...] renderObj = IMAGE renderObj { file.import.data = file:current:publicUrl altText.data = file:current:title params = class="lazy" } [...] 1828: Big news from AC Milan's official website: "The Milan players have just left their rooms after a rest. After a snack, there will be a team talk and the squad will leave for the San Siro Stadium at 18.40." You just don't get that sort of insight from English football websites, do you? "I'm stuck in work with no TV. I may have to resign and go to the pub for this game. Go Reds!"Paul, via text "Pub is beginning to fill here in Trafford. If we go through, the roof may blow off! 2-1 United!"via text on 81111 1730: It's confession time on 606: "I'm missing the game tonight because I am going to the cinema with a ladyfriend." Firstly, surely even a girl would understand the importance of a Champions League semi-final? Secondly, ladyfriend?? "Some of the locals look a bit bemused with all the street activity. The noise has subsided now and most of
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olini had given him the post of Minister of Communications, and his brother Arturo had founded a company to import coal from Germany, which thus became the "preferred" source of supply for the state railway in Italy, for which Ciano's ministry was responsible. Noble status and wealth made the young Galeazzo a good catch. On 24th April 1930 the regime put out the flags in staging the wedding of Mussolini's daughter to Ciano, and so recaptured the focus of public attention. Among the 512 guests included on the "exclusive" invitation list for the reception held in the gardens of the Villa Torlonia there were the most famous names of Rome's upper middle classes and aristocracy, surrounded by more than fifteen hundred security agents to keep order. The newspapers talked about the bride's elegant wedding dress, made by the Roman designers Montorsi, because the regime wished to support the Italian fashion industry, and also the hats and fur coats and capes worn by the female guests. Amid trays of cakes and chocolates, all of them made in Italy, the wedding party was a fitting continuation to the equally successful church ceremony: "At the top of the steps leading to the church doors, two rows of 'the Duce's musketeers', gloomy and rather sinister-looking in their black shirts and with their fierce expressions, awaited the exit of the bride and bridegroom, with their swords raised to form an arch, while behind them, gaily dressed in traditional costume, peasant women from the Romagna danced as at some country celebration. In later years several middle-class Roman weddings imitated the device of having the happy couple leave church under an arch of raised swords, sometimes held by children dressed in the uniforms of the Fascist youth movement." Mussolini presided at eight weddings in all: apart from Edda's, there were those of the three daughters of his sister Edvige and of Arnaldo's children, as well as the marriages of his own sons Vittorio and Bruno. All the ceremonies were held in the church of San Giuseppe, on the Via Nomentana, which became a kind of Mussolini family chapel, with the usual display of uniforms and fashionable dresses, and the tunnels of drawn swords – one of the regime's favourite symbols – held aloft to form a kind of arch of honour for the couple to pass through. And it was always Mussolini, as the head male of the clan, who accompanied the bride to give her away. "I stare at the portrait of Sandrino which Arnaldo sent me with a dedication written on it: 'To Benito, our leader, this branch of the tree broken off at the age of twenty'." In August 1930, barely four months after Edda's wedding, Arnaldo's eldest son, Sandro, died; his father never recovered from the blow and passed away on 21st December 1931. Mussolini thus found himself without the support of his brother, increasingly harassed by the thought of having to deal with things on his own and a lack of trustworthiness among his associates and the party leadership. At the same time, his relationship with Sarfatti, the only other person in whom he could confide, was drawing to an end. It is possible to speculate that a psychological connection might exist between the death of his brother, the end, shortly afterwards, of the relationship with Sarfatti (the only really meaningful one in the 1920s and early 1930s) and the increasing frequency of short-lived affairs, involving no emotional commitment, with women who must have flattered his male pride and confirmed to him, even in this private sphere of activity, his prestige and magnetism. [...] Whatever the case, it is certainly true that Arnaldo's death made Mussolini's human solitude almost total and exacerbated his psychological tendency to distrust people, his feeling that the associates who surrounded him were weak and vacillating, and that therefore he alone was the prime mover, the leader who had to do everything and to whom everything referred. From this time onwards, Mussolini turned in on himself completely, indulging in a series of brief but frequent sexual adventures. When he finally re-emerged from this period, he would come to rely more and more on the cloying, nest-like intimacy constructed for him by his new mistress Claretta Petacci. #### Chapter 17 Home Is Where the Heart Is Mussolini's sexual activities have been described as a whirlwind, but the term can be misleading; though prolific, they were in fact remarkably well organized by the staff in Palazzo Venezia. One only needs to look at the procedures carried out by the relevant secretarial office. Every day saw the arrival of numerous letters as well as telephone calls from female admirers; the women who already had Mussolini's private number could call him direct, while the others were put through a filtering process – in the office responsible for his private affairs – to ascertain whether they were suitable enough candidates for the Duce's consideration. The letters presented a real problem; the so-called experts in the private office examined each letter individually – they acquired in effect a real expertise in recognizing the handwriting on the envelopes. If it belonged to one of the women who was on the "authorized" list, the letter was forwarded to Mussolini unopened; if the hand was an unfamiliar one, then the envelope was opened and its contents examined. Once this had been done, the information contained in the letter was forwarded to a special police unit so that the appropriate security checks could be carried out. After the selection based on these checks was made, the letters which survived the filtering process were delivered to Mussolini, so that he could make a further selection of the women he wished to see; the preparatory procedures meant that he could be sure there were no problems of security with any of them. He usually saw them in the late afternoon. The social niceties were not observed – no introductory small talk to break the ice, no tea and biscuits were offered (only Claretta Petacci managed to get this). Mussolini's office, in the vast room known as the Sala Mappamondo (World Map Room), contained just three pieces of furniture: a huge desk, his own chair, and an armchair opposite for his visitor. The visits never lasted more than half an hour, and the women were never allowed to leave in a ruffled state – they would emerge with their hair combed and their clothes adjusted and trim. "Mussolini's technique varied according to the category of visitor: with the'regulars' he would use the huge carpet under the desk, while the 'newcomers' would be taken to one of the long stone seats which formed part of the window bays, covered with a thick mattress-like cushion designed to fit them. I realized this only because I was surprised to see Mussolini and his lady friends always in lively conversation, so I took to carrying out an inspection of the room: after a search I would find that the cushion in the window seat was rumpled, while from time to time I'd come across a dropped hair clip on the carpet." Mussolini's valet also recalled the different physical types of women who visited Mussolini, in demonstration of the fact that he had no particular preferences as far as this aspect was concerned: Signora B. was tall, dark-haired, plump and attractive, while T. from Rome, though still dark-haired, was skinny and plain; C. from Milan again was dark-haired but tall and well built, not too refined but not common either, whereas the Countess R. from Rovigo was a beauty, blonde and curvaceous. When Claretta Petacci, the curly-haired brunette whose breasts had caught and held Mussolini's attention, started to make inroads, the bewildering number of lovers started to decline; only a few of the long-term mistresses, what might be called the "historical" ones, managed to survive. At this point the meticulous efforts of the "private office" in the Palazzo Venezia were directed towards making sure Petacci's increasingly frequent visits were kept secret. Only two security guards and the valet Quinto Navarra were informed; the latter has described in his memoirs how the visits to Palazzo Venezia were organized so that no one ever saw her come or go. She would leave her home and take a taxi to a prearranged meeting place, where a motorbike with a closed sidecar would be waiting for her; she got into the sidecar, making sure the windows were covered with thick cloth panels. The motorcyclist was a plain-clothes policeman. They would cross the city, circle round Palazzo Venezia and enter through a rear doorway in Via degli Astalli. Any passer-by who saw the vehicle would assume it was just a courier carrying an urgent delivery. Once inside the inner courtyard, the "delivery" would emerge from the sidecar and take the private lift to the Duce's personal apartments on the first floor. Rachele knew about the visits, and wrote about them in a tone of understandable defensiveness (though the assertion about her husband's nights away from home is not true): "All the while this affair was going on, Benito never spent a night away from home. He never introduced Claretta Petacci to anyone or went out in public with her. They were forced to have brief rendezvous, usually in the small sitting room in Palazzo Venezia." Once in Palazzo Venezia, Petacci frequently had to wait for Mussolini to finish with his round of official visitors – the ministers, _gerarchi_, bankers and all the others
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is considered as a fused tetrahydro-*β*-carboline piperazinedione derivative with pendant 1,3-benzodioxol moiety at position 6 and a methyl substituent on the piperazinedione nitrogen, and it is of 2 chiral carbons both are of the absolute*R* configuration. In the present work, we report the synthesis of novel tetrahydro-*β*-carboline analogues and evaluate the activity of these compounds as PDE5 inhibitors. 2. Chemistry {#sec2} ============ The general synthesis of the target *β*-carboline hydantoin and *β*-carboline thiohydantoin derivatives is illustrated in Schemes [1](#sch1){ref-type="fig"}--[](#sch2){ref-type="fig"} [](#sch3){ref-type="fig"} [4](#sch4){ref-type="fig"}. Both *D*-tryptophan and *L*-tryptophan methyl ester were synthesized by a general synthetic procedure for amino acid esters. The ester and 2,4-dimethpxybenzaldehyde were subjected to a Pictet-Spengler reaction under nonstereospecific conditions. The diastereomeric nature of the produced *cis-* and *trans*isomers of the 1,3-disubistituted THBC (1--4) allowed their separation by column chromatography using CH~2~Cl~2~ : CH~3~OH (99.5 : 0.5) as an eluent. The respective pure *cis*or *trans*isomers were reacted with commercially available ethyl isocyanate, *t*-butyl isocyanate, and*p*-chlorophenyl isocyanate to produce the desired *cis- and trans*hydantoins isomers (5--16). Meanwhile, reaction with methyl and allyl isothiocyanate gave the *trans*thiohydantoins (17--20). The assignment of *cis/trans*stereochemistry for the tetrahydro-*β*-carbolines (1--4) was based on detailed study of ^13^C-NMR spectroscopy data well established in previous literature \[[@B6]\]. The ^13^C-NMR signals for C-1 and C-3 are more shielded in the *trans*isomer compared to *cis*isomer, so they appear more upfield in the carbon spectrum, with Δ*δ≈*3 for C-1and Δ*δ≈*1 for C-3. This is probably due to the 1,3-diaxial spatial crowding interaction present in the *trans*isomer, with the tetrahydropyridine ring exists in half-chair conformation; the ester at C-3 is equatorially located. On cyclization to the hydantoin or the thiohydantoin derivatives proton of C-1, the same proton makes a huge downfield shift to *≈δ*6.5. This deshielding effect can be explained by the electron withdrawing effect of the recently introduced carbonyl that causes ionization of the proton attached to C-5. A correlation exists between *R~f~* value on TLC and the stereochemistry of the respective *β*-carboline isomer. Thus, the *cis*isomer is systematically less polar than the *trans*isomer for 1,3-disubstituted THBCs. Meanwhile, for the hydantoin series, the polarity is reversed and the *cis*isomer becomes more polar than the *trans*isomer. Thus, for compounds **1--4**, with the stereochemistry: 1*R*, 3*R*; 1*S*, 3*R*; 1*S*, 3*S,* and 1*R*, 3*S*, their *R~f~* values were 0.38, 0.19, 0.39, and 0.18; meanwhile for the corresponding hydantoins **5--8,** their *R~f~*s were 0.57, 0.68, 0.57, and 0.68, respectively, using the same elution system. During the attempt to synthesize the thiohydantoin series with methyl or allyl isothiocyanate, only the *trans*isomers **(17, 18)** and (**19, 20**) were obtained. The fact that treating pure *cis-*THBC with isothiocyanate would only lead to the*trans*isomer was previously discussed \[[@B7]--[@B9]\]. Moreover, the ^13^C-NMR, ^1^H-NMR spectra, *R~f~*, and m.p. for each couple of the thiohydantoins obtained by treating the *cis-* and*trans-*THBC derived from *D*-tryptophan with the respective isothiocyanate were completely matching with those derived from the *trans-*and *cis*-THBC isomers derived from*L*-Tryptophan, respectively. This indicates the enantiomeric nature of the two products. Mass spectrometry to all derivatives showed the molecular ion peaks at M^+^; moreover, the THBC derivatives **1--4** showed molecular ion peak that was also the base peak indicating their stable nature. Also, compounds **1--4** showed an intense peak at M^+^-59 indicating that the Ester group (at C-3) was the most liable fragment to be lost on electron bombardment. The infrared spectra of all derivatives showed bands at a stretching frequency around 3400 cm^−1^ for the N-H stretching. All the THBCs **1--4** showed peaks at 1750 cm^−1^ for the ester carbonyl stretching. On the other hand, the *β*-carboline-hydantoin derivatives showed 2 carbonyl stretching peaks at *≈*1760 and 1700 Cm^−1^, as one of the carbonyls is flanked between 2 nitrogen atoms, meanwhile the other is flanked between an N and a C, respectively. 3. Biological Results and Discussion {#sec3} ==================================== All the new final compounds and intermediates were evaluated for their *in vitro* ability to inhibit the recombinant human PDE5, and the potency was expressed by an IC~50~ value (50% inhibitory concentration). Most of the compounds were evaluated in 2 steps; first, the percentage inhibition at a screening dose of 10 *μ*M performed in triplicate, second, compounds displaying a percentage of inhibition \>70%, the IC~50~ was determined by testing a range of 10 concentrations with at least two replicates per concentration. The results are cited in [Table 1](#tab1){ref-type="table"}. Tadalafil was used as a positive control. From the obtained PDE5 inhibition data, the following SAR conclusions can be withdrawn. The THBCs **1--4** showed marginal PDE5 inhibition that seems dependent upon the stereochemistry of C-1, with compounds**1** and **4** with C-1 of the *R* configuration more active than **2** and **3**, where C-1 is of the *S* configuration. Stereochemistry of C-5 of the *β*-carboline-hydantoin is the most crucial factor for activity. Thus, almost only those derivatives in which C-5 is of the *R* configuration (**5, 8, 9, and 12**) were the active PDE5 inhibitors. The only active compound with the C-5 S configuration was **6**; however, it is less active than its congenere with C-5 of the R configuration **5**, with IC~50~s of 0.72 versus 0.36 *μ*M. Interestingly, chiral carbon derived from amino acid even if with the *S* configuration (*L*-tryptophan) may lead to equiactive or more active isomers than those derived from amino acid with the *R* configuration (*D*-tryptophan). Herein, *β*-carboline-hydantoins with the C-5, C-11*a R,*and *S* configuration were more active than their analogues with the C-5, C-11*a R,*and*R* configuration this opens the horizons towards efficient PDE5 inhibitors derived from *L*-tryptophan rather than *D*-tryptophan. This may offer a highly economic advantage as*L*-tryptophan is much cheaper than *D*-tryptophan. The size (steric) and nature of the substituent on the hydantoin nitrogen seems as a modulator for activity and relative potency. Thus, the hydantoin derivatives with C-5 of the *R*-configuration and ethyl substituent on the hydantoin N, namely **5** and **8**, both showed IC~50~s of 0.36 and 0.36 *μ*M, respectively; congener compounds but with the N*-t*-butyl substitution **9, 12**were less active with IC~50~s of 2.4 and 0.56 *μ*M, respectively; additionally, similar compounds but with the aromatic bulkier *p*-chlorophenyl substituent were all inactive. This indicates that an aliphatic, less bulky substituent on the hydantoin N is better than bulkier aliphatic or aromatic substituent on the N. *β*-Carboline-thiohydantoins (**17--20**) are markedly less potent than the hydantoin derivatives congeners; only one congener **19** with *N*-allyl and C-5 of the *R*-configuration showed appreciable activity with IC~50~ 0.55. It is worthy to mention that Daugan and coworkers showed that the
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sit around, smoke dope and protest while I'm paying taxes to support them. Fuck them. In addition, they are taking resources away from other areas and other people are getting hurt because of them. You sure support wonderful folks. They leech off other people and take away police protection and other people are going to be dead because of them. Fuck them. Send them to mexico or yemen and then they can protest. Anon 3:24, it's time you learned the truth: Nowhere did I make the argument that OWS, let alone the entire "protest", has as its primary function and ultimate goal the act of deficating on police cars. All that happened in your fevered imagination. I'm beginning to think you actually handle the excrement you're so obsessed with. It goes a long way in explaining your sickness. FP, your strategy and point were clear enough. I know what you meant. You sought to diminish the legitimacy of the Occupy Wall Street protesters and ignore the political substance of their message by suggesting that they are "stinking dirty ugly racists," and holding up the few who have caused problems (defecating on police cars and "trashing" parks) as representative of the whole. To drive that point home, in your last post, you put the word protest in quotation marks, implying that it isn't really a protest. If that isn't your point, then I'm not having difficulty with comprehension; you're the one having difficulty expressing yourself. As is evidenced by your last childish and unnecessarily crude post, you obviously are incapable and/or unwilling of having a serious discussion about anything. What's the matter? Did I offend your delicate sensibilities? Is it possible that I was able to get you to condemn my "childish and unnecessarily crude post" while at the same time get you to defend the OWS crowd whose antics are far more childish and crude? And that's being charitable: they really are filthy, childish, oblivious to the implications of their redistributionist message (if they can even manage to be coherent at all), and racist. No, not all of them (which was never my point), but it begs the question: just what is it about a movement that attracts far more than its fair share of kooks, anarchists, and other assorted human debris, with the full blessing of the communists, the nazis, and... top Democrats. Birds of a feather, I guess. Strange, but the Tea Party never had that problem, and yet you attach all sorts of ugly epithets to them. All of them. Without a shred of proof. is it really any surprise at all that the most wanted traffickers are from mexico given that our insatiable demand for drugs is supplied overwhelmingly by that country? this is simple economics. the war on drugs has been an abysmal failure and created problems far more severe than drug-addiction. in the face of mounting evidence, the possession, production and distribution of many illicit drugs will be de-criminalized. it's inevitable. your ignorance and seemingly deep-rooted hatred of mexicans amazes me. why would you expect americans to populate the lists of wanted drug traffickers when illicit drugs are overwhelmingly produced in mexico? mexicans, are, again, simply doing the jobs that americans won't - and in this case, can't - do. After six years in the online lead generation market at TARGUSinfo, we launched Loud Castle to optimize lead gen programs. Today, our lead management platform manages millions of online leads for lead buyers and sellers on a monthly basis. Not only do lead sellers improve lead transparency, they can score and determine which leads best match each lead buyer.lead managementMethacrylates in dental restorative materials. Commercial dental restorative materials were analysed in order to obtain information about the occurrence of sensitizing acrylates. Acetone-soluble methacrylates of 7 bonding materials, 8 composite resins and 2 glass ionomers were identified by gas chromatography with mass-selective detection and quantified by liquid chromatography with ultraviolet detection. The most frequently occurring methacrylates in the bonding materials were 2-hydroxyethyl methacrylate (2-HEMA) and 2,2-bis-[4-(2-hydroxy-3-methacryloxypropoxy)phenyl]-propane (bis-GMA). Bis-GMA and triethyleneglycol dimethacrylate were the most frequently occurring methacrylates in composite resins. The main methacrylate of the 2 glass ionomers was 2-HEMA or trimethylolpropane trimethacrylate. Information about methacrylates was given in the safety data sheets (SDSs) for about half of the products that according to the analysis results contained methacrylates. SDSs need to be improved so that the health risks for dental personnel can be reliably assessed and controlled.Nagalkuzhi Nagalkuzhi is a village in the Sendurai taluk of Ariyalur district, Tamil Nadu, India.The village has famous sivan temple which was built 200 yrs ago. Demographics As per the 2001 census, Nagalkuzhi had a total population of 3379 with 1655 males and 1724 females. References Category:Villages in Ariyalur districtGeographic distribution of an extinct equid (Equus hydruntinus: Mammalia, Equidae) revealed by morphological and genetical analyses of fossils. Equus hydruntinus inhabited Europe and the Middle East for more than 300 000 years. For a long time, palaeontological data failed to place E. hydruntinus into the equid phylogenetic tree, confronted with the fact that it shares primitive Equus characters with both zebras and asses, and derived characters with asses and hemiones. However, the study of a recently discovered skull points to a relationship with hemiones. Extraction of DNA from ancient samples from Crimea (E. hydruntinus) and Iran (E. cf. hydruntinus) yielded 134-288 bp of the mtDNA control region and 143 bp of the cytochrome b gene. This DNA analysis supports the proximity of E. hydruntinus and Equus hemionus suggested by skull and limb bone analyses, and rejects proximity to either Equus burchelli or the asses suggested by tooth morphology. Dental morphology may thus be of poor taxonomical value if used alone for establishing equid phylogenetic relationships. Furthermore, the small genetic distance between E. cf. hydruntinus of Iran and the classical E. hydruntinus of Crimea suggests that both samples belong to the same species. Accordingly, the geographic range of E. hydruntinus -- until now believed to be restricted to Europe, Israel, and Turkey -- can be extended towards East as far as Iran.Children's Environmental Health: Beyond National Boundaries. Children are especially vulnerable to environmental pollution, a major cause of disease, death, and disability in countries at every level of development. This article reviews threats to children, including air and water pollution, toxic industrial chemicals, pesticides, heavy metals, and hazardous wastes. Global climate change is expected to exacerbate many of these issues. Examples of innovative nongovernmental organizations and governmental programs that address the impacts of environmental hazards on children are included. International travel, adoption, migration, and movement of goods and pollutants worldwide make these conditions concerns for all pediatricians.Nuclear medicine and pediatric nephrology. Radionuclide cystography and renal scintigraphy are the diagnostic procedures of choice in conjunction with ultrasonography in the workup of pediatric urologic or nephrologic patients. Two interesting case reports--a six-month old and a three-month old--are presented.Sunday, May 27, 2012 So, I know I raved about this potato salad a few weeks ago, but this Armenian one--made for a dinner with my mom and some friends--was equally fantastic. Horseradish mustard and celery seeds are swapped out in favor of lemon and dried mint. I think this recipe, which I've had bookmarked forever, originally came from Simply Armenian. Like most of the Armenian dishes I've made, its simplicity is part of its deliciousness. It's important not to overcook the potatoes; remember that they will continue cooking even after you strain them and rinse them with cold water. A few days after making this salad, I threw in some really ripe grape tomatoes. Their sour juiciness went perfectly here. 1. Boil potatoes in salted water until just pokeable with a fork, perhaps 10-15 min. Don't overcook them! Strain and place in cold water. 2. Combine remaining ingredients, then strain potatoes and toss them in this dressing. Allow to sit several hours to chill and for flavors to meld. It is that time of year again! I was going to make this fava bean pasta sauce again and finally get a decent photo, but I realized I didn't have near enough favas. What I did have, however, was a blackened eggplant ready for baba ganoush. I used favas instead of tahini in this recipe, and the result was surprisingly similar. Favas have a slighly funky/nutty character to them that other green-colored beans lack. Wednesday, May 23, 2012 In making this Italian wedding soup from my vegan cookbook, I used different pasta, and instead of homemade meatballs I used 2 Tofurkey Italian sausages I found in my freezer. Instead of raw kale I threw in a bunch of sauteed collards I already had in my fridge. And sadly,
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}) = A_{i}x(t) - A_{i}c_{i} + f(c_{i}).$$This system can be used to obtain the next reachable set together with a bloating factor that accounts for the difference between the original and the linearized dynamics $$\mathcal{R}_{i + 1} = (c_{i} + \psi(A_{i},\tau)f(c_{i});\, e^{A_{i}\tau}G_{i}) \oplus \beta_{\epsilon},$$where *β*~*ϵ*~ can be computed iteratively as proposed in \[[@RSOS160790C42]\]. Here, we use the zonotopic set representation to obtain a tight estimate of the effect of nonlinearity. Consider the error function *ϵ*(*x*)=\|*f*(*x*)−\[*A*~*i*~(*x*−*c*~*i*~)+*f*(*c*~*i*~)\]\|---using a substitution of *x* by (*c*~*i*~+*dx*), we obtain *ϵ* as a function of *dx*, the distance between a point and the centre. We define an upper bound for *dx*, as in equation ([3.7](#RSOS160790M3x7){ref-type="disp-formula"}): ${\{|dx|_{\max}\}}_{i} = \sum\limits_{k = 1}^{p}|{\{ g_{k}\}}_{i}|$, and approximate *ϵ*(*x*) with a function monotonously increasing with *dx*. Hence, we obtain an estimation for which $\epsilon(x) \leq \hat{\epsilon}(|dx|_{\max})$ and construct a generator set $$G_{l} = \text{diag}\{\hat{\epsilon}(|dx|_{\max})\},$$which represents a bound on the nonlinearity of the system. To obtain the reach set of the time-interval \[*iτ*,(*i*+1)*τ*\] further approximations have to be applied to enclose all trajectories between the two time-points. As the piece-wise linear system is time-varying, the estimation of the time-interval \[0,*τ*\] is not sufficient. Instead, as mentioned before (see also in electronic supplementary material, figure S1(b)), the convex hull of two delimiting reach sets is calculated and bloated, the bloating factor for which can be derived in several ways, e.g. as in \[[@RSOS160790C9]\] or \[[@RSOS160790C42]\]. Although the computation in equation ([3.11](#RSOS160790M3x11){ref-type="disp-formula"}) assumes a constant time-step, it can be modified to incorporate variable steps, *τ*~*i*~, without loss of efficiency, as in the nonlinear case the matrix exponential, e^*A*~*i*~*τ*^, should anyway be computed in each iteration. Consequently, the first-order linearization used above can be combined with a higher-order, adaptive method by computing the central trajectory (*c*~*i*~) and each time-step (*τ*~*i*~) with the higher-order numerical technique, followed by reachable set computation based on these quantities. This way stiff systems with rapidly changing dynamics can be tackled without significant additional computing time, and slowly changing systems can gain a speed-up compared with fixed time-step calculations. Alternatively, we could replace the linearization with a more flexible description of the stochasticity than the LNA, such as moment closures \[[@RSOS160790C30]\] or finite-state projection methods \[[@RSOS160790C43]\]. 4.. Example applications {#s4} ======================== 4.1.. Control of gene expression noise {#s4a} -------------------------------------- The first example considered is a controlled stochastic gene expression system \[[@RSOS160790C28],[@RSOS160790C44]\]. In spite of its simplicity, this model is one of the most important examples in practice as protein production is a necessary and elementary building module in real and synthetic biological systems. Many applications might rely on the steady operation of such a unit, hence it is of great practical interest to know what the achievable noise levels and possible states of operation are. Let us take a simple depiction of protein production that focuses on two macromolecules, mRNA and protein, captured in two quantities of interest (mRNA and protein copy numbers, *m* and *p*, respectively). The overall process is broken up into four reactions, as follows: $$\begin{matrix} \varnothing & {\overset{k_{1}\,\mu}{\rightarrow}\text{mRNA}(\text{transcription}),} \\ \text{mRNA} & {\overset{k_{2}}{\rightarrow}\varnothing\quad(\text{mRNA\ degradation}),} \\ \text{mRNA} & {\overset{k_{3}}{\rightarrow}\text{mRNA} + \text{protein}\quad(\text{translation})\text{and}} \\ \text{protein} & {\overset{k_{4}}{\rightarrow}\varnothing\quad(\text{protein\ degradation}),} \\ \end{matrix}$$where the symbol ∅ represents that a molecule is produced from (or degraded into) some substance not modelled in the representation. This system translates into the stoichiometry matrix $$S = \begin{bmatrix} 1 & {- 1} & 0 & 0 \\ 0 & 0 & 1 & {- 1} \\ \end{bmatrix},$$with each column standing for molecular abundance changes during a reaction of the ones listed above. The propensity of each reaction is formed by its characteristic rate and the molecular species' abundances, $$a_{1} = k_{1}\mu;\quad a_{2} = k_{2}m;\quad a_{3} = k_{3}m\quad{and}\quad a_{4} = k_{4}p.$$In this example, the dimensionless multiplier in the first reaction, *μ*, represents our control over the transcription rate, assuming either discrete (*μ*=0 or *μ*=1) or continuous (*μ*∈\[0,1\]) values. A typical control signal would be a sequence of zeros and ones, delivered through, e.g. a light-sensitive set-up \[[@RSOS160790C45]\], switching transcription on and off for some time period. After performing the LNA, we obtain a set of five ordinary differential equations, determining the time-evolution of the mean of *m* and *p*, the variance of *m* (*σ*~*m*~), the covariance of the two species (*σ*~*mp*~) and finally the variance of the protein abundance (*σ*~*p*~), $$\frac{d}{dt}\begin{bmatrix} m \\ p \\ \sigma_{m} \\ \sigma_{mp} \\ \sigma_{p} \\ \end{bmatrix} = \begin{bmatrix} {k_{1}\mu - k_{2}m} \\ {k_{3}m - k_{4}p} \\ {- 2k_{2}\sigma_{m} + k_{1}\mu + k_{2}m} \\ {k_{3}\sigma_{m} - (k_{2} + k_{4})\sigma_{mp}} \\ {2k_{3}\sigma_{mp} - 2k_{4}\sigma_{p} + k_{3}m + k_{4}p} \\ \end{bmatrix}.$$The system is started from $\mathcal{I} = \underline{0}$, corresponding to no previously produced target molecules in the system and we investigate the reachable sets up to time *T*=10 with time-step *τ*=0.01. The time-units are normalized according to the protein's average turnover time, so that we gain a general model that might be later scaled to reflect a specific macromolecule. Therefore, *k*~1~ has units of \[molecules/time-unit (t.u.)\], and all other *k*~*i*~ are in \[1/t.u.\]. We choose the reaction rates $\underline{k} = \lbrack 100,5,100,1\rbrack$ to show biologically relevant ratios of reaction speeds and steady states: under constitutive production there will be on average 20 mRNA and 2000 protein molecules. [Figure 1](#RSOS160790F1){ref-type="fig"} shows projections of the final reachable set together with two sample trajectories. The samples are computed as the mean and variance of a population consisted of 10 000 direct realizations of the original stochastic system. The input signal *μ*(*t*) is defined as a piece-wise constant function with values randomly drawn from {0,1} and switching every 60 or 30 s (*u*~1~ and *u*~2~, respectively); the signal is kept the same for all realizations contributing to a particular trajectory in [figure 1](#RSOS160790F1){ref-type="fig"}. We also take into account some uncertainty regarding the protein degradation rate, i.e. that the value of *k*~4~ is unknown or can be externally changed to values within 5% of the nominal value, 1. The light blue regions in [figure 1](#RSOS160790F1){ref-type="fig"} show the estimate of the reachable set under such uncertainty. Interestingly, while a substantial part of the mRNA---protein mean space can be covered, the reachable states on the protein mean---variance plane are limited to a very narrow band. Therefore, if relying on the production of a protein with this module we will have to make a compromise: either have a low number of proteins produced, or a high amount but with great variability (as may be expected given the Poisson nature of this
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held in contact for some time. Elastic tubes are readily formed of india rubber by cutting it into uniform slips of proper thickness and winding them round rods of polished glass or metal, so that the edges are in close contact or "overlapping." A piece of tape is then wound round outside it, and the whole boiled in water for 2 or 3 hours, after which time the edges will be found to be sufficiently adherent. A better plan is to immerse the "rubber" in a mixture formed of bisulphide of carbon, 95 parts, and rectified spirit, 5 parts, until it swells into a pasty mass, which may then be moulded into any desired form or passed through the die of a tubing machine. For chemical purposes, brewing, &c., vulcanised india-rubber tubing has now taken the place formerly occupied by the unprepared material. The once celebrated "Mackintoshes" are made by spreading two or more coats of a paste made of caoutchouc and rectified coal-tar naphtha over the surface of the stuff or cloth, and, when it has become partially dry, pressing two such surfaces evenly together by passing the goods between a pair of cylinders or rollers. The articles are then placed in a stove room for the composition to harden, and to remove the odour of the naphtha. Of late years vulcanised or mineralised rubber () has been used for this purpose, and being spread on the outside of the stuff instead of the inside forms an ornamental and thoroughly waterproof material. India-rubber thread is prepared by stretching it (previously cut into coarse filaments) to 5 or 6 times its length in boiling water or hot air, in which state it is allowed to cool slowly. This process is repeated again and again until it reaches 16,000 or 17,000 times its original length, when it is glazed by agitating it with powdered sulphur or French chalk. This thread is readily joined or "pieced," as it is called, by paring the ends obliquely with a pair of scissors or a knife, and then pressing the clean ends strongly together with the fingers. When the coarse filaments from the cutting machine are simply stretched with the moistened thumb and finger in the act of "reeling" to about 8 or 9 times their length, they are said to be "inelasticated," and are ready to be made into elastic braces, elastic web, and other like elastic tissues and fabrics in the braiding machine. =Caoutchouc, Vul'canised.= _Syn._ VULCANISED INDIA RUBBER, MINERALISED I. R., SULPHURETTED I. R. The discovery of the singular action of sulphur and the mineral sulphides on caoutchouc was made by Mr Charles Goodyear, of New York, in 1842, at which date the manufacture of vulcanised india rubber may be said to have commenced. In 1843 Mr Thomas Hancock patented a process for vulcanised india rubber in these countries, founded on that of Mr Goodyear. A sheet of caoutchouc immersed in melted sulphur absorbs a portion of it, and at the same time undergoes important changes in many of its leading characteristics. So prepared, it is no longer affected by changes of temperature; it is neither hardened by cold nor softened by any heat insufficient to destroy it. It loses its solubility in the solvents of ordinary caoutchouc, whilst its elasticity is greatly augmented, and has become permanent. The same effect is produced when sulphur is kneaded into caoutchouc in a masticator, or by means of powerful rollers, as well as when common solvents (naphtha, spirit of turpentine, &c.) are charged with a sufficient amount of sulphur in solution to become a compound solvent of the rubber. In these cases articles may be made of any required form before heating them for the change of condition technically termed "vulcanisation." It is necessary, however, for this purpose that the form should be carefully maintained both before and during the exposure to the heat. "A vulcanised solid sphere of 2-1/2 inches in diameter, when forced between two rollers 1/4 inch apart, was found to maintain its form uninjured. In fact, it is the exclusive property of vulcanised caoutchouc to be able to retain any form impressed upon it, and to return to that form on the removal of any disturbing force which has been brought to act upon it." (Brockedon.) Caoutchouc combines with from 12% to 15% of sulphur; the quantity of sulphur added to the naphtha paste should not, therefore, exceed 10% or 12% of its weight. The temperatures for vulcanisation by the common method range from 320 deg. to 330 deg.; and the period required is one hour or more, according to the temperature. A much lower temperature is, however, sufficient if the duration of the exposure is much extended or the compound mass is softened with any of the common solvents of india rubber. The process of sulphuring, or mineralisation, is differently conducted in different manufactories. Under Mr Burke's patent, oxysulphide or amorphous sulphide of antimony (formed by decomposing a solution of crude antimony in a lye of potash or soda with hydrochloric acid) is employed. This powder he combines with either india rubber or gutta percha, or mixtures of them, by kneading in a "masticator" for 2 or 3 hours, and after strong compression in a mould whilst still warm, he exposes the mass to a steam heat ranging from 250 deg. to 280 deg. Fahr. The block, so prepared, is afterwards cut into sheets, &c. The advantages possessed by the product are that it possesses no unpleasant odour, nor does the sulphur effloresce on its surface, as in ordinary vulcanised india rubber. Under Mr Christopher Nickel's patent (1849) 1 part of sulphur is kneaded with 6 parts of caoutchouc, and then pressed into moulds, as before. He also vulcanises rubber by exposing it in a cylinder heated in a steam jacket to the fumes of sulphur or to sulphuretted gases, given off from a retort connected with the apparatus. The rubber thus prepared he next subjects to hydraulic pressure in moulds, at a temperature ranging between 220 deg. and 250 deg. Fahr. Small articles or sheets of india rubber may be extemporaneously vulcanised at common temperatures by simple immersion, for a minute or two, in a mixture of bisulphide of carbon, 97-1/2 parts, and protochloride of sulphur, 2-1/2 parts; after which they must be well washed first in weak alkaline lye, and next in pure water. Mr Parkes employs 100 instead of 97-1/2 parts of the bisulphide. This method is termed "cold sulphuring." An excellent method of vulcanisation, recommended by Mr Parkes, particularly applicable to small articles, consists in immersing them for about 3 hours in a close vessel containing a solution of polysulphide of potassium at 25 deg. Baume (sp. gr. 1.197), and of the temperature of 240 deg. Fahr. It is afterwards washed in an alkaline lye, then in pure water, and dried. Among the many applications of vulcanised india rubber those connected with its elasticity and its enormous contractile power when extended are particularly striking. Under Mr E. Smith's patent, "torsion springs" for roller blinds, door springs, clock springs, carriage springs, &c., are made of it. Mr Hodges, in another patent, has availed himself of the same property as a new mechanical power. Short lengths of caoutchouc, which he terms "vulcanised power purchases," are successively drawn down from or lifted to a fixed bearing, and attached to any weight which it is required to raise; when a sufficient number of these power purchases are fixed to the weight, their combined elastic force lifts it from the ground. Thus, 10 purchases of the elastic strength each of 50 lbs. raise 500 lbs. Each purchase is 6 inches long, and contains about 1-1/2 oz. of vulcanised caoutchouc. These 10 purchases, if stretched to the limit of their elasticity (not of their cohesive strength), will lift a weight exceeding 650 lbs. The same principle has been applied to relieve and equalise the strain on ships' cables, especially where several boats are towing one vessel; and as a projectile force. A number of power purchases, attached to the barrel of a gun constructed to project harpoons, will exert a power, if suddenly relieved, proportioned to their aggregate forces. By similar contrivances balls may be projected 200 yards or more, and a charge of No. 4 shot can
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) was an American former pro basketball player. He spent three seasons in the National Basketball Association (NBA), one with the Los Angeles Lakers (1973-74) and two with the Phoenix Suns (1974–76). The Mount Vernon, Illinois, native attended Southern Illinois University prior to his NBA stint. He died at age 54 outside his home in Tempe, Arizona, suffering a massive heart attack. Category:1951 births Category:2005 deaths Category:African-American basketball players Category:Basketball players from Illinois Category:Los Angeles Lakers draft picks Category:Los Angeles Lakers players Category:New Orleans Jazz expansion draft picks Category:People from Mount Vernon, Illinois Category:Phoenix Suns players Category:Southern Illinois Salukis men's basketball players Category:American men's basketball players Category:Shooting guardsPolice arrested 1 suspect and now they are looking for 2 more for the robbery of a 60 year old man. Police received a call about a robbery reportedly at 5:15 p.m. near South 12th Street, near 14th Avenue. Reportedly 3 robbers robbed the victim at gunpoint and wanted his money. All three suspect got away but Newark police reacted quickly and search the area and arrested one of the suspects. Tareef Atkins, 20, of Newark. Tareef Atkins has been charged with robbery, conspiracy and weapon charges. ​Anyone with information about the other assailants was asked to call the Newark 24-hour Crime Stopper tip line at 1-877-NWK-TIPS (1-877-695-8477) or 1-877-NWK-GUNS (1-877-695-4867). Police said all tips are kept confidential and could result in a reward.Adjuvant chemotherapy after complete resection in non-small-cell lung cancer. West Japan Study Group for Lung Cancer Surgery. We performed a study to determine whether postoperative mild chemotherapy to maintain the patient's quality of life (QOL) and immunoactivity could also prolong survival. From December 1985 to July 1988, 323 patients with completely resected primary non-small-cell lung cancer (stage I to III) were enrolled. The subjects were randomized into three treatment groups, as follows: cisplatin (CDDP) 50 mg/m2 body surface, vindesine (VDS) 2 to 3 mg/kg body weight for three courses, and 1-year oral administration of tegafur (FT) plus uracil (UFT) 400 mg/kg body weight (CVUft group, 115 patients); 1-year oral administration of UFT 400 mg/kg body weight (Uft group, 108 patients); or surgical treatment only (control group, 100 patients). The overall 5-year survival rates were 60.6% for the CVUft group and 64.1% for the Uft group versus 49.0% for the control group. The results of statistical testing were P =.053 (log-rank test) and P =.044 (generalized Wilcoxon test) among the three groups, P =.083 (log-rank) and P =.074 (Wilcoxon) between the CVUft and the control groups, and P =.022 (log-rank) and P =.019 (Wilcoxon) between the Uft and the control groups, which indicates higher survival rates in the CVUft and the Uft groups compared with the control group. A multivariate statistical analysis on prognostic factors using Cox's proportional hazards model was performed with the following results: P =.037, hazards ratio = 0.64 with a 95% confidence interval (CI) of 0.42 to 0.97 (control v CVUft group); and P =.009, hazards ratio = 0.55 with a 95% CI of 0.36 to 0.86 (control v Uft group). Significantly favorable results were obtained in the CVUft and Uft groups compared with surgery alone. These data showed significant prognostic advantages in the postoperative adjuvant chemotherapy groups.Two of the most frequent issues encountered when we ship overseas are the time frame and the costs incurred. Some observations and tips from our BH members to ensure smooth passage are: Be conscious of timeframe, and realize some items (even with International Priority, or Express) may be held up in customs and out of your control. With custom orders it may be helpful to convo before completing the transaction, or clearly state shop policies regarding fees that may be added on due to shipping costs to various countries. Realize that a delay in payment may not be an international issue, but maybe more due to the buyer being a newbie, and unsure of how to complete payment. So always say "Thank you for your purchase! Your item is ready to ship out as soon as payment has been completed. If you are having trouble on how to complete payment, you can refer to this tutorial: http://www.etsy.com/help_guide_checkout.php" Regular first class mail is usually not much more than domestic mail. (Compare that to Priority. One member had a Canadian buyer who requested Priority International -- Canada Priority Mail -- that cost $15 and took 6 weeks to get there). To send something regular first class mail you need a customs declaration form. Keep in mind that the receiving country may have duties that the seller has to pay. Because of that, one member lists the product value at $50 or under and simply puts "craft items" in the description. Some countries can be problematic. Consider Fedex or DHL when shipping to any country in Africa, Latin America and Eastern Europe, or countries without reliable home mail delivery.Production Assistant Salaries in Brownsville, Texas Alternate Job Titles: Production Associate, Production Assistant What is the average Production Assistant salary for Brownsville, TX? How much does a Production Assistant in Brownsville, TX make? The median annual Production Assistant salary in Brownsville, TX is $26,120, as of November 30, 2016, with a range usually between $25,022-$27,244 not including bonus and benefit information and other factors that impact base pay. However, the salary for someone with the title Production Assistant may vary depending on a number of factors including industry, company size, location, years of experience and level of education. Our team of Certified Compensation Professionals has analyzed survey data collected from thousands of HR departments at companies of all sizes and industries to present this range of annual salaries for people with the job title Production Assistant in Brownsville, TX. This chart describes the expected percentage of people who perform the job of Production Assistant in the United States that make less than that annual salary. For example the median expected annual pay for a typical Production Assistant in the United States is $26,120 so 50% of the people who perform the job of Production Assistant in the United States are expected to make less than $26,120. This chart describes the expected percentage of people who perform the job of Production Assistant in Brownsville, TX that make less than that salary. For example 50% of the people who perform the job of Production Assistant in Brownsville are expected to make less than the median. Source: HR Reported data as of December 2016 Responsible for ensuring the production quality of all promotionals, commercials, and public service announcements. May require an associate's degree or its equivalent with 0-2 years of experience in the field or in a related area. Has knowledge of commonly-used concepts, practices, and procedures within a particular field. Relies on instructions and pre-established guidelines to perform the functions of the job. Works under immediate supervision. Typically reports to a supervisor or manager. View full job descriptionnext Image 1 of 2 prev Image 2 of 2 The Latest on tropical cyclone (all times local): 11:05 p.m. Mozambique's president says more than 200 people are confirmed dead in his country alone after a tropical cyclone roared ashore in the southern African nation over the weekend. President Filipe Nyusi announced the death toll while meeting with his ministers in the largely destroyed city of Beira, the Portuguese news agency Lusa reported late Tuesday. The president also announced three days of national mourning and said his government would declare a national emergency. Hundreds of thousands of people remain at risk as rivers burst their banks, torrential rains continue and flood waters rise, stranding some people on rooftops and in trees. ___ 10:45 a.m. Hundreds are dead, many more missing and thousands at risk from massive flooding in Mozambique, Malawi and Zimbabwe caused by Cyclone Idai and persistent rains. International aid agencies and government officials are scrambling Tuesday to rescue families trapped by the floodwaters from rivers that have burst their banks and are still rising. Mozambique's President Filipe Nyusi said the death toll could go as high as 1,000 from the cyclone and flooding. Although emergency workers caution they do not know if the fatalities will reach that estimate, they say this is the most destructive flooding in 20 years. Hardest hit by the cyclone is Mozambique's Beira port, a city of 500,000, where thousands of homes have been destroyed. Flooding waters have inundated large areas of rural Mozambique and its neighboring countries.Q: How to sort a list by values (from a matrix) and break ties by first minimum, then by 2nd minimum, etc.? Let's say I have a matrix where each column is associated with a value. For example: A = [[ 7.41, 5.44, 4.
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journalists and academics and NGO people," says Steffen. "We have seen with some regularity stuff that we have pushed hard on starting to become much more mainstream. The fact that journalists are out there paying attention to blogs now and using blogs as a research tool means that if they see something done well, explained well and frequently mentioned, they're much more likely to pick it up and run with it." And the blogs themselves are starting to enter the territory of old media: A few green blogs are even providing jobs for their creators. Gristmill is the blog adjunct of Grist, the respected online environmental magazine (I write for Grist from time to time), so Roberts is technically an employee of the magazine, although he says he has complete editorial freedom. Worldchanging, which was incorporated as a nonprofit just a year ago so it could accept foundation grants, now pays key staff like Steffen, although writers are not (yet) paid. And later this year, green blogs will take an even more definitive step into the world of mainstream media: A collection of essays on sustainable solutions from Worldchanging contributors will be published as a book, on actual paper. But for most of the green bloggers, blogging is its own reward. Sustainablog's Jeff McIntire-Strasburg, for example, is the epitome of the noble Jeffersonian citizen-blogger: a concerned individual with something to say and a knack for saying it just the right way. The former English professor lives in Saint Louis and writes his highly regarded blog in his spare time. Even Treehugger, considered by many bloggers to be the Web's premier guide to stylish green living, is funded by founder Hill's successful Web and design businesses. So do I need a blog? This column already has certain bloglike elements: It appears only online and has an RSS feed, even though it's carefully scheduled and edited on the tried-and-true old-media model. Many of the topics covered here are exactly the things you might find on Worldchanging or Gristmill. It's a crowded field, and as the lines continue to blur, maybe that's the wrong question to ask. Maybe the right question is, How long before it becomes a blog?Immunological characterization and transmembrane topology of 5-hydroxytryptamine3 receptors by functional epitope tagging. 5-Hydroxytryptamine3 (5-HT3) receptors are the only known monoamine receptors mediating fast excitatory responses in mammalian neurons. Their primary structure as well as their electrophysiological and pharmacological properties show a phylogenetic relation to nicotinic acetylcholine, GABAA, and glycine receptors. As a prototypical member of this gene superfamily, we investigated the membrane topology of functional homomeric 5-HT3 receptors by using epitope tagging of the channel subunits expressed in heterologous systems. Visualization of 5-HT3 receptors in transfected COS-7 cells, either in western blot (molecular mass 61.2 +/- 0.8 kDa) or in situ, was performed with previously characterized antibodies recognizing artificial epitopes as well as with anti-fusion protein antibodies directed against a wild-type receptor intracellular domain. The extracellular location of the distal C-terminal tagged domain demonstrates the presence of a fourth transmembrane domain in 5-HT3 serotonin-gated channels. In this region, the significant homology between members of this class of neurotransmitter-gated channels suggests strongly that they have a common transmembrane organization basically different from glutamate-gated and ATP-gated channels. 197 Kan. 417 (1966) 417 P.2d 139 FRANCES SIMONICH, Executrix of the Estate of John J. Heath, Deceased, Appellee, and WOODROW K. GINGERY, ELIZABETH GINGERY and DOROTHY DePAULI, Interveners-Appellees, v. MADENA WILT, Appellant. No. 44,535 Supreme Court of Kansas. Opinion filed July 22, 1966. James P. Cashin, of Prairie Village, argued the cause, and John J. Lyons, Jr. and James R. Pusateri, both of Prairie Village, and Fred J. Freel, of Kansas City, Missouri, were with him on the brief for the appellant. Walter G. Klamm, of Kansas City, argued the cause, and Chas. F. Burkin, Jr., also of Kansas City, was with him on the brief for the appellee, Frances Simonich, Executrix. John J. Ziegelmeyer, of Kansas City, was on the brief for the Interveners-Appellees. The opinion of the court was delivered by SCHROEDER, J.: This is an action at law instituted by the executrix of an estate claiming as an asset of the decedent's estate moneys in a joint tenancy bank savings account standing in the names of the decedent and Madena Wilt (defendant-appellant). The case was tried to the court and appeal has been perfected by the defendant from an adverse judgment, holding the joint tenancy bank account was impressed with an oral trust on behalf of the devisees and legatees under the will of the decedent. The primary question in this case is whether the competent evidence presented in the record establishes the creation of a valid joint tenancy bank savings account with the right of survivorship. John Heath, a widower, returned to Kansas City, Kansas, from California following the death of his second wife during the latter *418 part of 1961. He established his residence in Kansas City with Madena Wilt, a daughter by his first marriage, and her husband, George Wilt, under an arrangement whereby Madena was to care for him in his old age. Heath had previously been in the real estate business and although advanced in years and in questionable physical health, all witnesses considered him to be competent and able to conduct his business up until his death. The joint tenancy account in controversy was created during the latter part of July, 1962, when Heath and his daughter, Madena, went to the Twin City State Bank in Kansas City, Kansas, for that purpose, after Heath had sold part of his real estate holdings in California, from which he realized cash sums approximating $28,200. Heath and his daughter, Madena, conferred with Charles Dodsworth, executive vice-president at the bank, with whom they were acquainted, and Heath requested Dodsworth to set up a joint savings account with right of survivorship between himself and his daughter, Madena Wilt. Dodsworth and Heath discussed the right of survivorship with respect to the account in question, the fact that either party could draw on the account, and that in the event of the death of either of them, the survivor would take the balance then remaining. Thereupon, at Heath's request, Dodsworth had both Heath and his daughter, Madena, sign a signature card establishing a joint tenancy account between them with right of survivorship. Deposit was concurrently made in the approximate amount of $27,000, and the passbook was given by Heath to Madena Wilt who retained the same in her possession. (The petition alleged the account in question, a sum of money in excess of $26,000, stood in the name of John J. Heath and Madena Wilt as joint tenants. This allegation of the petition was admitted in the answer.) Subsequent deposits and withdrawals were made to and from the account by Madena Wilt. The funds deposited were provided by the decedent Heath, and the funds withdrawn were for his use and benefit during his lifetime. Prior to his death, Heath told Madena and her husband that upon his death the money remaining in the joint account was to be hers. The decedent also told his son, Wilbur Heath, that he had the joint account all fixed up the way he wanted. Heath died testate on the 26th day of December, 1962, a resident of Kansas City, Kansas. Frances Simonich (plaintiff-appellee), also *419 a daughter by Heath's first marriage, was duly appointed executrix of his estate on the 4th day of February, 1963. The decedent had not told Frances Simonich about the joint tenancy bank account in controversy during his lifetime, and she did not learn of its existence until sometime after his death. On the 1st day of November, 1963, the executrix filed her petition in the court below claiming moneys on deposit in the above described bank account on the date of the decedent's death as an asset of the decedent's estate, alleging that the decedent created the account as a matter of convenience and did not intend that it go to Madena upon his death, but that the funds should be distributed in accordance with the terms of his will. The other heirs, interveners, appear in this action in support of the executrix' position, likewise claiming an interest in the decedent's estate. Issue was raised by the defendant's answer, which admitted the creation of the joint tenancy bank account, but denied that the decedent did not intend that it go to the defendant upon his death. The executrix' evidence in support of her theory of recovery was that on various occasions after the creation of the joint tenancy account, the decedent had mentioned to the executrix and other relatives that he desired his children and stepchildren to share equally in the proceeds of his estate, and that in his opinion each would receive approximately $10,000. Other testimony was admitted by the trial court concerning an effort made by the decedent to establish residence with a daughter in California to no avail prior to the establishment of the joint bank account here in question. The trial court, among other things, found: "3. That an account was established in the Twin City State Bank of Kansas City, Kansas, during the lifetime of John J. Heath, deceased, in
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{1\over2}}^{\infty} v_k^4\ \Bigl[ Q_+ (k), Q_+^\dagger (k) \Bigr] + \sum_{k ={1\over2}}^{\infty} u_k^4\ \Bigl[ Q_- (k), Q_-^\dagger (k) \Bigr] - V_0 (z) \.$$ Thus far it would appear to suffice to consider the $ Q $ operators and $ z $ for the determination of the spectrum. This changes if one addresses the constrained mode $ a_0$ as the constraint cannot be expressed purely in terms of $ Q $ operators. From Eq.(\[hamall\]) and (\[defcharge\]), one finds $ a_0$ makes its appearance in the Hamiltonian both linearly and quadratically which we separate into $ H_{Constr} = H_{Constr}^{(1)} + H_{Constr}^{(2)} $. The term linear in $ a_0$ is $$H_{Constr}^{(1)} = 2 \sum_{k ={1\over2}}^{\infty} \Bigl[\ u_k^3\ \Bigl(B^\dagger_k Q_- (k) + Q_-^\dagger(k) B_k \Bigr)_s + v_k^3\ \Bigl(D^\dagger_k Q_+ (k) + Q_+^\dagger(k) D_k \Bigr)_s \ \Bigr] \.$$ The term quadratic in $ a_0$ is $$H_{Constr}^{(2)} = \sum_{k ={1\over2}}^{\infty} \Bigl[\ u_k^2\ \bigl(B_k B_k^\dagger + B_k^\dagger B_k \bigr) + v_k^2\ \bigl(D_k D_k^\dagger + D_k^\dagger D_k \bigr) \ \Bigr] \.$$ $ H_{Constr} $ could have a non-zero VEV that could contribute to the potential of the gauge mode. There are two possibilities where such nonvanishing contributions could arise. The first is when an $ a_0$ appears either to the extreme left or extreme right in $ H_{Constr} $. However, preliminary studies of the structure of the constraint suggest that no non-zero VEV of $ a_0$ or $(a_0)^2$ can arise. Thus, the role played by this mode is quite different from that of its counterpart in the $(\phi^4)_{1+1}$ theory. The second possibility of non-zero contribution to the gauge potential is when the zero mode lies between an annihilation operator on the left and a creation operator on the right, such as $ \langle 0| b_k a_0 a_0 b^\dagger_k |0 \rangle$. A nonzero VEV could potentially arise from such contributions if $[ a_0, b_k ]$ and $[ a_0, b^\dagger_k ]$ are non-zero. This completes the analysis of the light-cone Hamiltonian. In summary though, we have reexpressed the Hamiltonian as a sum of three contributions, [*i.e.*]{}$$H = H_{Gauge} + H_{Fock} + H_{Constr} \. \label{hamsum}$$ In the next section we will see how far analytic methods can take us in diagonalizing parts of the Hamiltonian. Finally, we should emphasize that we have refrained thus far from [*ad hoc*]{} approximations to define a consistent Hamiltonian and Hilbert space. As we are unable to give here exact analytical solutions we consider their numerical simulation as a challenge for the future. In the sequel we therefore will continue with several simplifying assumptions which will allow us to solve part of the Hamiltonian analytically. The most drastic among them is the omission of the constraint part. We thus will concentrate efforts in the following on solving approximately $ H_{Gauge} $ and $ H_{Fock} $ subject to the omission of $ H_{Constr} $. Approximate Solutions in the Gauge Sector ========================================= The potential energy $ V_0 (z)$ which appears in $ H_{Gauge} $ via Eq.(\[gaugepot\]), [*i.e.*]{} $ H_{Gauge} \equiv - 4 {d^2 / d z^2} + V_0 (z)$, is what we shall loosely refer to as the ‘gauge potential’. As analyzed in Appendix \[sec:gaugepot\] it is [*invariant*]{} under large gauge transformations. One therefore can restrict oneself to calculate it only for the fundamental modular domain $0 < z < 1$. In Fig.1 it is displayed for the two cases explained below. In either case, because of the singular behaviour at $ z = 0$ and $ z = 1$, there will be a discrete spectrum of excitation energies in this potential. These will be labelled by a quantum number $N$. Generalizing the representation in [@KPP94] we use a wavefunctions $\Psi_{N}(z) \equiv \langle z |N\rangle$ so that we address ourselves to solving the Schrödinger equation $$H_{Gauge} \Psi_{N}(z) = \widetilde E_{N} \Psi_{N}(z) \.$$ The symbol $E_N$ will be reserved for the vacuum normalized eigen-energy, namely $\widetilde E_{N} - \widetilde E_{0}$. In the fundamental modular domain the potential is symmetric about $ z = {1\over2}$. As mentioned, it is singular at $ z = 0$ and $1$. It has a minimum at $ z = {1\over2}$, however the value of the function there is actually divergent. Moreover its curvature diverges at that point, that is $ V_0 ''({1\over2}) \propto \omega_0^2 \ln{s}$, $s \rightarrow \infty$, where $s$ is the value of a dimensionless regulator truncating sums. The precise meaning of this divergent behaviour, namely whether it is physical or formal, is unclear to us. Lacking a definite answer, we pursue below the two alternative scenarios, labelled (a) and (b). Let us take the point of view that the divergent $\ln{s}$ behaviour of the potential should be cancelled by a counterterm in the Lagrangian. In fact we do not know what this counterterm should be and the answer may come from the, as yet unavailable, solution to the constrained zero mode $a_0$. We therefore proceed by simply numerically subtracting the function $\omega_0^2 \ln{s}\ (z - {1\over2})^2 $ from the explicit expression in Appendix \[sec:gaugepot\]. We plot the so-obtained function in Fig.1. Upon inspection, one notes the very flat base in the vicinity of $ z =1/2$. A good approximation might therefore be the infinite square well. Restoring units, the problem is expressed by $ - L (g /2 \pi)^2 (d^2/dz^2) \Psi_{N} = \widetilde E_{N} \Psi_{N}$. After a vacuum energy subtraction, the eigen-energy [*densities*]{} $\epsilon_{N} \equiv E_{N}/ (2 L)$ are $ g^2 (n^2 - 1)/8$. We thus recover the spectrum for SU(2) pure zero mode glue in 1+1 dimensions as obtained in [@Het93a; @Het93b], and verified by us on the light-cone in [@KPP94]. Wavefunctions respecting boundary conditions are then ${\rm{sin}}(N \pi z)$ up to normalization. As for subtleties concerning this choice over the cosine we refer the reader to [@KPP94]. Thus we have succeeded in diagonalizing the gauge part of $ P^-$. As the vacuum part of $P^+$ has no dependence on $z$ these wavefunctions are also eigenfunctions of $P^+$ with momentum zero. For reasonably large values of the cutoff $s$, the $\ln{s}$ term dominates, as mentioned, over the $s$-independent part and thus here the latter can be omitted. As discussed in Appendix \[sec:gaugepot\], with the cutoff finite but large the gauge potential can be approximated by $$V_0 (z) = V_0 ({\textstyle{1\over2}}) + 4\omega^2 (z -{\textstyle{1\over2}})^2\, \quad\ {\rm with}\quad \omega^2 = \omega^2_0 \ln{s} \. \label{harmonic}$$ The numerical value of $\omega_0^2$ is given in Appendix \[sec:gaugepot\], while ${V_0}({1\over2})$ is an unspecified constant. The eigenvalues and eigenfunctions are now those of the harmonic oscillator, $$\widetilde E_{N} = V_0 ({\textstyle{1\over2}}) + 4\omega (2N+1) \, \quad\ {\rm and} \quad \Psi_{N} (z) = {\cal N}_N {\rm H}_N \Bigl(\sqrt{\omega} (z -{\textstyle{1\over2}}) \Bigr) \,{\rm e}^{-{\omega \over 2} (z - {1\over 2})^2} \,$$ respectively, where the $ {\rm H}_N$ are the Hermite polynomials of order $N$, and where the ${\
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"Shut up. I mean the word 'unquote' and you know it." I took a good stretch and an unpatted yawn. "Too much sitting and no walk. Six hours at the typewriter. Mrs. Brooke deliberately insulted me on the way out. It was at her suggestion that they came. She wanted to find out how much you knew. A month ago she told her husband that she knew or suspected that Susan was going to marry a quote nigger end of quotation. She knew where the apartment was; she had been there. She had to kill Susan; it wouldn't have solved the problem to kill Dunbar because Susan would merely have picked another one—the way she saw it. The alibi is piddling. For something as important as a murder you couldn't be blamed for leaving a boy in bed asleep, or even for putting just a touch of pentobarbital sodium in his milk. Or Mother Brooke came and baby-sat, knowing or unknowing. Filicide is no more unheard-of than sororicide. What have I left out?" "Three little points. She said Susan Brooke was a lady. She didn't consider her one, and doesn't. She knew that Mr. Whipple lives not far from that apartment. She dropped her bag when she stood up. Where does she live?" I went to my desk, got the Manhattan book, and found the page. "Park Avenue in the Sixties. Sixty-seventh or -eighth." "How would she have gone?" "Probably a taxi. Possibly her own car if she has one." "Get Saul. Has she a car, and if so, did she use it that evening. Your notebook." I objected. Saul Panzer's rate was ten dollars an hour, plus expenses, and this was on the house. I asked politely, "Am I crippled?" "You have another errand—Mr. Oster and Mr. Whipple. Your notebook. For tomorrow's paper, one will do, the _Gazette_. Single column, say two inches. Headed 'A cabdriver,' fourteen-point, boldface. Following, eleven-point standard: 'took an attractive well-dressed woman, comma, around thirty, comma, from the Sixties to One Hundred and Twenty-eighth Street early in the evening of Monday, comma, March second. It will be to his advantage to communicate with me.' Below, my name and address and telephone number. To run three days, tomorrow, Monday, and Tuesday. Any comment?" "One. _East_ Sixties." "Insert it." "She may spot it. Does that matter?" "No. If she's open to menace, the more she's stirred the better. Your notebook. Questions for Mr. Oster and Mr. Whipple. We don't want an army here. Only those who—" "I'll get the ad in first." I got the phone and dialed. # Chapter 8 It was a lousy weekend. Nothing went right. Nothing went exactly wrong either, but you can say that if you just go to bed and don't get up. My Saturday morning date with Oster and Whipple was canceled because Oster was called to Washington for a parley at the Department of Justice. He might be back Sunday night. Saul Panzer is the best free-lance operative who ever stopped a closing door with his foot, but even Saul was stymied when he learned that the man who had been on duty that Monday evening at the garage where the Kenneth Brookes kept their two Herons was off somewhere for the weekend, nobody knew where. At four o'clock Saturday afternoon I was invited to the DA's office to discuss some selected items in the report I had delivered to Cramer, and was kept so long by an assistant district attorney named Mandel, who would enjoy looking at me through bars with him on the outside, that I was two hours late for a dancing date with friends at the Flamingo. Lon Cohen phoned once Saturday and twice Sunday. Some brainy journalist, maybe Lon himself, having seen the ad, had recalled the fact that Susan Brooke's married brother lived in the East Sixties, and of course 128th Street was obvious, and Lon wanted to know what gave. I stalled him off Saturday, but he called twice Sunday to ask if the hackie had shown. He hadn't. Not a peep. A lousy weekend. I finally got to Oster early Monday afternoon, at the office of the ROCC, a whole floor of a building on 39th Street near Lexington Avenue. It wasn't lavish, but neither was it seedy. I was a little surprised to see that the switchboard girl, who doubled in reception, was my color, even a little lighter—a middle-aged female, hair showing some gray, with a chin and a half and a long thin nose, which didn't fit. I learned later that of the total office staff of thirty-four, five were white, and of the five whites, four were volunteers, what Dolly Brooke would call do-gooders. Oste's room was small, one window, but after a few words he took me down the hall to the corner room of the executive director, Thomas Henchy, and it was quite a chamber, with a few dozen photographs on the walls where the cabinets and shelves left room. I had seen Henchy on television a couple of times, and so have you probably—broad shoulders, cheeks a little pudgy but not flabby, short neck. Color, strong coffee with one teaspoon of cream. He got up to shake hands, and I took a little care with the grip. Men with short necks are apt to be knuckle-crushers. When I left, more than an hour later, the program for the evening was set, with no hard feelings. I had explained that when Wolfe had said "the entire staff" he hadn't meant it literally. He wanted to see only those, who, because of their contacts or relations with Susan or Dunbar, or both, might possibly be able to supply useful information; and the selection would be up to them, Oster and Henchy, in discussion with me. That was satisfactory, and we proceeded to discuss. I had a list in my pocket when I left, and when I got back to the office I typed it for Wolfe: **Thomas Henchy**, around 50, executive director. He was courteous but not cordial. He knows it's doing ROCC a lot of harm and he hates it. Possibly thinks Whipple killed her. **Harold R. Oster**, Counsel. He had evidently told Henchy that a conference at our office was his idea, and I didn't spoil it. **Adam Ewing**, around 40, colored, in charge of public relations, worked closely with Whipple. I met him. Smart and very earnest. Thinks he knows everything, and possibly does. Chips on both shoulders. Light caramel. **Cass Faison**, 45, colored, in charge of fund-raising. Susan Brooke worked under him. I met him. They don't come any blacker. Turns his grin on and off. I wouldn't be surprised if he liked Susan and doesn't like Dunbar. No innuendo intended. **Miss Rae Kallman**, about Susan's age, white. She helped Susan arrange meetings and parties. Susan recruited her and paid her personally, but she is staying on for a while. Didn't meet her. I got the impression that she didn't approve of Susan's cottoning to Dunbar. I didn't go into points like that since I wasn't supposed to, but I got the impression. **Miss Beth Tiger**, colored, 21, stenographer. Only Henchy has a secretary, they're short-handed, but she took all of Dunbar's dictation. Another impression, from a comment by Henchy: she would have been willing to take more than dictation from Dunbar. Didn't meet her. **Miss Maud Jordan**, white, 50 or more, switchboard and receptionist. She is included chiefly because she took the phone call from Susan that afternoon and put the message on Dunbar's desk that Susan couldn't get to the apartment until nine o'clock. She's a volunteer, hipped on civil rights, another do-gooder, evidently with a private pile since she takes no pay and Henchy mentioned that she gave $500 to the fund for Medgar Evers's children. I saw her entering and leaving. An old maid, spinster to you, who had to be hipped on something and happened to stumble on civil rights or maybe wrongs. My impression, based on my infallible understanding of women under 90. All of them knew about the apartment. Henchy, Ewing, Faison, and Kallman knew where it was. Oster says he didn't. Jordan knew the phone number. Tiger, I don't know. When Wolfe came down from the plant rooms at six o'clock he picked it up, read it twice, scowled at it for two minutes, put it in a drawer, and picked up his current book. Not Rowse on Shakespeare; _The Minister and the Choir Singer_, by a lawyer named Kunstler. I had read it and recommended it. At dinner we discussed it and agreed that the New York Police Department and district attorney's office had never made
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$t_{min} = 1.5\pm0.1$ day at 11cm and $t_{min} =1.1 \pm 0.1$ day at 6cm. The latter time scale is visible in both, the 6cm data sets from Effelsberg and Urumqi. At 11cm and 6cm another break near $t_{max} = 2.9\pm0.1$ days is only marginally significant, since it is longer than half of the duration of the observations. For this slower variability ($t > 2.5-3$ days) the data indicate higher variability amplitudes at 11 cm than at 6 cm. The SF curves at 11 cm and 6 cm wavelengths are characterized by two different slopes. The SF curve at 11 cm follows a power-law slope, $\beta = 0.90\pm0.04$ until $t_{min}$ (with $SF \propto t^{\beta}$) and then $\beta = 2.02\pm0.11$ from $t_{min}$ to $t_{max}$, while at 6 cm $\beta = 0.98\pm0.05$ until $t_{min}$ and $\beta = 1.67\pm0.06$ from $t_{min}$ to $t_{max}$. The SF of the data at 2.8 cm, however, shows a more pronounced and faster variability than for the two longer wavelengths. This is also seen in the auto-correlation functions (see Section 3.3 and Fig. \[fig6\]). The characteristic time scales of variability at 2.8 cm wavelength are $t_{min} = 0.50\pm0.05$ days and $t_{min} = 1.4\pm0.1$ days and the SF curve is characterized by a slope $\beta = 0.65\pm0.06$ until $t_{min}$ and $\beta = 1.37\pm0.17$ from $t_{min}$ to $t_{max}$. Below $t \approx 3$ days, the variability at 2.8 cm appears more pronounced than that at 11 cm and 6 cm. However, Table 1 shows that the measurement uncertainty $m_0$ at 2.8 cm is 1.1 per cent, which is 3 to 4 times higher than at 11 cm or 6 cm. Although the formal significance of variability at 2.8 cm is higher than 99.9 per cent, the larger measurement uncertainty at this wavelength should lead to a cautious interpretation of the variability in this band. While in the first half of the 2.8 cm light curve the variability is very low ($m=1.15$ per cent), we note in the second half a continuous rising trend in flux density, which is the main reason for the high significance of the overall variability. Since a departure from this rising trend is not seen, the true variability amplitude could be higher and the variability time scale could be longer than 1.4 days. In summary we find that the fastest and most pronounced variability is seen at the shortest radio wavelength (2.8cm) with a characteristic time scale of $0.5\pm0.05$ days. Common to the three radio data sets (11, 6, and 2.8cm) is also a slower variability mode, which appears at a characteristic timescale of 1.1 days at 6cm and to 1.4-1.5 days at 11cm and 2.8cm. The structure function at 2.8cm differs substantially from the more similar ones seen at 6cm and 11cm. Such different shapes toward higher frequencies were also seen previously in this source (Fuhrmann et al. 2008) and were interpreted as indication for the presence of physically different variability mechanisms, as e.g. interstellar scintillation dominating at the longer wavelength and a with frequency increasing contribution of source intrinsic variability. In this context, variability time scales which are seen in the 2.8cm data, but are not seen in the 11cm and 6cm data, may be related to some source intrinsic variability and may well therefore appear also in the optical, which is not affected by interstellar scintillation. In the optical bands S5 0716$+$714 also displayed remarkable variability during the campaign period. The most dense coverage at optical frequencies was obtained in the V and R passbands. The SFs of these data are shown in Fig. \[fig3\]. They show rapid variability with multiple cycles of rises and declines. Differences between both SFs are likely due to the different time-sampling in both data sets and the location of observing gaps within the two data trains. The B and I passband light curves are much sparser and so cannot reveal significant features in the SF analysis. We therefore focus on the SFs for R- and V-bands. The first break in both R and V band SF curves appears at a timescale of $t_{min} = 0.25\pm0.05$ days. At R-band the SF shows pronounced maxima also at $0.50\pm0.05$ days, $0.90\pm0.05$, $1.4\pm 0.1$ days and $1.9\pm 0.1$ days. At V-band the variations are less rapid, with a dominant time scale at $0.8\pm0.05$ days and $1.9\pm 0.1$ days. The 0.5day and the $1.4\pm 0.1$ day time scale, seen in R-band, are not seen in V-band. We note that these time scales are within their measurement errors factor of two multiples of each other, providing a hint of an underlying 0.25day quasi-periodicity (QPO). We further note that at 2.8cm the shortest timescale seen in the SF is 0.5days, which is very close to the second harmonic of the optical variability. This might indicate some correlation between radio and optical. We check the possibility for such a correlation in Section 3.3. We investigate the possibility for QPOs being present in the optical data using other techniques in Section 3.6. Auto- and Cross-correlations ---------------------------- To quantify the correlation among the multi-frequency light curves of the source during the campaign period, we computed the discrete auto and cross correlation functions (ACF, DCF) between different frequencies to search for possible time lags. We followed Edelson $\&$ Krolik (1988) and Lehar et al. (1992) to calculate the DCF with details given in Rani et al. (2009). In Figure \[fig4\] we plot the two auto-correlation functions (ACF) of the 6cm data from the Effelsberg and Urumqi telescopes. The differences seen in the shape of the two ACFs is explained by the different data-quality from the two telescopes, with a higher signal-to-noise ratio and smaller beam size (and therefore lower in beam confusion) at the larger telescope. In Figure \[fig5\] we show the DCF of the 6cm data from the Effelsberg and Urumqi telescopes. 0716+714 was observed at both telescopes with very similar time sampling and time coverage. The high degree of correlation of the two data trains is obvious and convincingly demonstrate the reality of the observed intra-day variability. No significant time lag ($\tau_{6.0/6.0} = 0.0\pm0.05$) is seen between the two telescopes. Similar to the structure function analysis (see Fig. \[fig3\]) the auto-correlation functions of the 11cm and 6cm Effelsberg data show a common shape and show similar decorrelation time-scales (Fig. \[fig6\]). On the other hand, the 2.8cm data decorrelate much faster, indicative of faster variability at this shorter wavelength (higher frequency). The ACFs of the 11cm and 6cm bands also suggest a regular pattern on a $\sim 2$day timescale. Since this timescale is just half of the duration of the overall $\sim 4$day time coverage of the radio data, we do not regard this timescale as significant. To search for possible timelags between the three radio bands, we performed a cross-correlation analysis of the Effelsberg radio data. Figure \[fig7\] shows the two independent cross-correlations of the 11.0cm and 6.0cm light curves versus the 2.8cm data. Formally we calculate a time lag of $\tau = - (1.2 \pm 0.1)$day between 11.0cm and 2.8cm in the sense that the 2.8cm data lead. Such frequency dependence is consistent with the canonical behavior seen in AGN (e.g. van der Laan 1966, Marscher & Gear 1985). Next, we look for a possible correlation with flux variations at optical-radio frequencies. Figure \[fig8\] (top) may indicate a correlation with $\sim (0.35 \pm 0.15)$day time lag between R and and 2.8cm, in the sense that radio is leading over optical, which apparently is opposite to physical expectations (the higher frequency should come first). At V-band the maximum correlation with 2.8cm occurs at zero time lag, however, with a lower cross-correlation coefficient than for R-band (DCF peak at: 0.73 for R-band, 0.53 for V-band). Since the R- and V-bands cross-correlate very strongly with zero time lag (Fig. \[fig9\]), we think that the above time lag of $\sim 0.35$day is unlikely to reflect physical reality. The R-band light curve shown in Fig.\[fig
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解体党文化》](https://github.com/gfw-breaker/jtdwh.md/blob/master/README.md) | [《共产主义的终极目的》](https://github.com/gfw-breaker/gczydzjmd.md/blob/master/README.md) <img src='http://gfw-breaker.win/banned-news/pages/prog202/a102795143.md' width='0px' height='0px'/>Plasma pharmacokinetics, bioavailability, and tissue distribution in CD2F1 mice of halomon, an antitumor halogenated monoterpene isolated from the red algae Portieria hornemannii. The purpose of the present study was to define the plasma pharmacokinetics, bioavailability, and tissue distribution in mice of halomon, a halogenated monoterpene from Portieria hornemanii that is active in vitro against brain-, renal-, and colon-cancer cell lines. Halomon formulated in cremophor:ethanol:0.154 M NaCl (1:1:6, by vol.) was injected i.v. at 20, 60, 90, or 135 mg/kg into female CD2F1 mice. Doses of 135 mg/kg were also given i.p., s.c., and by enteral gavage to female CD2F1 mice and i.v. to male CD2F1 mice. Plasma halomon concentrations were measured with a gas-chromatography system using electron-capture detection. Halomon concentrations were also determined in the brains, hearts, lungs, livers, kidneys, spleens, skeletal muscles, fat, red blood cells, and, if present, testes of mice given 135 mg/kg i.v. Halomon plasma pharmacokinetics were well fit by a two-compartment, open linear model and were linear between 20 and 135 mg/kg. Population estimates of parameters describing halomon plasma pharmacokinetics in female CD2F1 mice were developed with a standard two-stage technique and also by simultaneous modeling of data from 20-, 60-, 90-, and 135-mg/kg i.v. studies in female mice. Halomon bioavailability was 45%, 47%, and 4% after i.p., s.c., and enteral dosing, respectively. Urinary excretion of the parent compound was minimal. Halomon was distributed widely to all tissues studied but was concentrated and persisted in fat. Halomon concentrations measured in the brain were comparable with concomitant concentrations detected in plasma and most other tissues. These data and models are helpful in the simulation and evaluation of conditions produced by preclinical screening and toxicology studies.1 Shares 0 1 0 It is a perverse irony that as video war games move into 3-D reality on our computer screens, the real war games that are playing with people’s lives around the world become one-dimensional, presented in black and white packaging without proper context. So it is that the recent atrocity committed with extreme malice against Yemeni civilians in their capital Sana’a with bombs dropped by Saudi war-planes had to vie for attention in the Western media alongside the deaths of similar numbers of Haitians struck at random by Hurricane Matthew. The vital context missing from the reports on the Sana’a massacre – which said that at least 140 people were killed and over 500 hundred injured by four bombs dropped minutes apart – was any explanation, not of who was responsible, but of why they would do something so unbelievably barbaric. There was never any question of who was responsible for the attack, because video of the burning building following the first strike recorded the next bomb-drop as well as the roar of the war-plane that dropped it. (There have been a number of dreadful car-bomb attacks on mosques in Sana’a before, so this might otherwise have been a possibility) In the hours after the strike, the Saudis first refused to acknowledge responsibility – a preposterous claim which only confirmed not just their responsibility but their malicious intent – on which more shortly. Their guilt and that of their partners was further emphasized by a short-lived threat from the US to suspend arms shipments to Saudi Arabia. And on this threat we must suspend disbelief! The US is not just some sleeping partner in the Saudi coalition, or in the ongoing war to reinstall the illegitimate Saudi-supported exile ‘government’ of Abed Rabbo Mansour Hadi. Indeed, given the overwhelming US military presence in Yemen’s region, including the centre for East African operations in Djibouti, we might conclude that this is really just another US coalition – operating under the Saudi ‘flag of convenience’. Not only are the Saudi planes supplied and presumably maintained by the US, but all the missiles and bombs – cluster bombs and bunker busters and who knows what else – have been supplied by the US, and even re-supplied during the course of the war on Yemen. In addition to that is the ‘assistance with targeting’ provided by US and UK personnel both on the ground in the Saudi peninsula and through multiple surveillance platforms. This interdependency between the US and the Saudis can hardly be concealed, yet its true nature cannot be admitted. Even more taboo is the evident close cooperation between the Saudis and Israel, who have recently found shared interests in Syria and a common enemy in Iran. Given these links it was impossible to believe the US would really ‘review its cooperation’ with the ‘Saudi Coalition’ – or should have been. But no matter – within days of the review the US found a reason to renew arms supplies to fight the Houthis when missiles were fired at the USS Mason in the Red Sea from Yemen. Or this is what they said. Some astute observations were made by the ‘Off-Guardian’, suggesting not only that Houthi forces were extremely unlikely to have been responsible for the missile attack, but that the US ‘response’ – launching cruise missiles at ‘Houthi Radar installations’- was actually the intended action for which the ‘Houthi missile attack’ was the necessary pretext. As they also observed, the atrocity just committed against Yemenis in Sana’a was a rare opportunity to turn international sympathy in their direction, and they would have been unlikely to squander it with a useless provocation against a US navy vessel. At about the same time as this direct entry into the Yemen conflict by the US, the results of an internal Saudi enquiry into the funeral bombing were released, finding that the strike was ‘not authorised’ and ‘based on false information from a Yemeni army source’. It is hard to get your head around the double-think and mendacity of these claims, and it was clearly beyond the mental capacity of some mainstream Western media reporters. This was despite these media having themselves revealed the true motive behind the Saudi’s murderous attack. In its first report on the bombing, Australia’s SBS news showed the footage mentioned above of the airstrike with its giveaway sound track, but also and rather unusually speculated on a possible motive for the attack, showing a list of names of a dozen military chiefs and government members killed in the airstrike. The funeral was for a respected tribal leader and so the attendance of these important figures in the Ansarullah government was to be expected. The problem for SBS was that the Saudis’ ‘false information’ was exactly what SBS had shown to be true only a few days earlier – that top figures in the Houthi military leadership were present at the funeral as claimed by their source, and the strike – a perfect opportunity to ‘decapitate’ the new Yemeni government – was quite clearly not ‘un-authorised’. But SBS baulked at this chance to finally start reporting news instead of just passing on US/NATO propaganda about the ‘Iranian-backed Houthi rebels’ fighting a ‘civil war’ against the ‘internationally-recognised’ Mansour Hadi government. Perhaps it had no choice, after passing on a carefully woven but completely false narrative about Yemen for the last five years. No regular listener to SBS, or any other Western media station could have much idea that of all the countries upset by the contrived ‘Arab Spring’, Yemen’s ‘revolution’ remained the most genuine and the most promising for her people. And as such was as threatening as Syria to the agenda and interests of the US-UK-Saudi coalition that has been trying to destroy it. Most of those hapless followers of the Western MSM would have no idea that Yemen has a functioning government based in the capital Sana’a and supported by the vast majority of Yemenis, and that the ‘internationally recognized’ government is not actually recognized by Yemenis because they had no part in electing it. Yemen has a functioning government based in the capital Sana’a and supported by the vast majority of Yemenis. Just before the Saudi-led bombing campaign began in March 2015, talks on a ‘power-sharing agreement’ between the Houthis, former President Saleh’s faction and the now-exiled leaders finally collapsed, with the resignation of the UN mediator Jamal Benomar. Hadi – who was never elected but merely appointed following the ousting of Saleh – was long past his mandate, but his Saudi backers refused to concede to the Houthis. There have been periodic breaks in the bombing campaign, with UN-mediated talks on a ‘peace agreement’, but which never go anywhere. As with other asymmetric conflicts in the region – notably in Palestine and Syria – the ‘peace’ sought by the aggressors is
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value1 = 1, value2 = x, referenceList = new List<ReferenceModel> { new ReferenceModel {ID = 55, NumberType = Mean} } }; The syntax you use works well for arrays of native types (double, ints), but not classes with properties. Welcome to my my Portfolio Page. This is where you'll find my professional work (and some personal pieces as well).As always, I'm unable to post my current work, as it's for films that have yet to hit the big screen.Don't forget to visit my BLOG. There's more of my work there, plus a bunch of other fun stuff./* * Licensed under the Apache License, Version 2.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. */ package app.metatron.discovery.query.druid.queries; import com.fasterxml.jackson.annotation.JsonIgnore; import com.fasterxml.jackson.annotation.JsonTypeName; import com.fasterxml.jackson.databind.annotation.JsonSerialize; import java.util.List; import java.util.Map; import java.util.Set; import javax.validation.constraints.NotNull; import app.metatron.discovery.domain.datasource.Field; import app.metatron.discovery.domain.workbook.configurations.datasource.DataSource; import app.metatron.discovery.query.druid.Aggregation; import app.metatron.discovery.query.druid.Dimension; import app.metatron.discovery.query.druid.Filter; import app.metatron.discovery.query.druid.Granularity; import app.metatron.discovery.query.druid.Having; import app.metatron.discovery.query.druid.Limit; import app.metatron.discovery.query.druid.PostAggregation; import app.metatron.discovery.query.druid.Query; import app.metatron.discovery.query.druid.serializers.GranularitySerializer; import app.metatron.discovery.query.druid.virtualcolumns.VirtualColumn; @JsonTypeName("groupBy") public class GroupByQuery extends Query { @NotNull Granularity granularity; @NotNull List<String> intervals; List<VirtualColumn> virtualColumns; List<Dimension> dimensions; GroupingSet groupingSets; Filter filter; @NotNull List<Aggregation> aggregations; List<PostAggregation> postAggregations; Limit limitSpec; Having having; Set<String> outputColumns; Map<String, Object> context; @JsonIgnore private Field geometry; public GroupByQuery() { super(); } public List<Dimension> getDimensions() { return dimensions; } public void setDimensions(List<Dimension> dimensions) { this.dimensions = dimensions; } public GroupingSet getGroupingSets() { return groupingSets; } public void setGroupingSets(GroupingSet groupingSets) { this.groupingSets = groupingSets; } public List<VirtualColumn> getVirtualColumns() { return virtualColumns; } public void setVirtualColumns(List<VirtualColumn> virtualColumns) { this.virtualColumns = virtualColumns; } public Limit getLimitSpec() { return limitSpec; } public void setLimitSpec(Limit limitSpec) { this.limitSpec = limitSpec; } @JsonSerialize(using = GranularitySerializer.class, typing= JsonSerialize.Typing.DYNAMIC) public Granularity getGranularity() { return granularity; } public void setGranularity(Granularity granularity) { this.granularity = granularity; } public List<String> getIntervals() { return intervals; } public void setIntervals(List<String> interval) { this.intervals = interval; } public Filter getFilter() { return filter; } public void setFilter(Filter filter) { this.filter = filter; } public List<Aggregation> getAggregations() { return aggregations; } public void setAggregations(List<Aggregation> aggregations) { this.aggregations = aggregations; } public List<PostAggregation> getPostAggregations() { return postAggregations; } public void setPostAggregations(List<PostAggregation> postAggregations) { this.postAggregations = postAggregations; } public Having getHaving() { return having; } public void setHaving(Having having) { this.having = having; } public Map<String, Object> getContext() { return context; } public void setContext(Map<String, Object> context) { this.context = context; } public Set<String> getOutputColumns() { return outputColumns; } public void setOutputColumns(Set<String> outputColumns) { this.outputColumns = outputColumns; } public Field getGeometry() { return geometry; } public void setGeometry(Field geometry) { this.geometry = geometry; } public static GroupByQueryBuilder builder(DataSource dataSource) { return new GroupByQueryBuilder(dataSource); } } The Straight Dope A while ago I saw a tagline on alt.fan.cecil-adams from someone who was darn proud to be a member of the National Rifle Association. I asked if the Second Amendment to the U.S. Constitution still holds water today since the intent was to provide guns and protection against the other side of the puddle. This sparked a huge debate on the Net about the right to bear arms with, as usual, both sides claiming they are right. I figured it's time to take it to the top and ask you to settle it all for us. Is it time to reevaluate the Second Amendment? If only so that those who argue can at least now argue an up-to-date amendment? --Colin Joyce, Scranton, Pennsylvania You mean well, Colin, but you couldn't write a proper question to save your soul. What you want to know is what the framers of the Bill of Rights intended the Second Amendment to mean, and whether their intention has any continuing legal relevance in view of the (supposedly) dramatically altered social landscape upon which we gaze today. The answer to the second question is easy: yes, else why have a constitution? But the answer to the first is knottier. Historically there have been two interpretations of the Second Amendment: the states-rights argument and the individual-rights argument. The states-rights view is that the Second Amendment merely guarantees the states the right to organize militias and citizens the right to join. (Militia here means any armed force raised for the common defense, not just the national guard.) The individual-rights view is that the Second Amendment means what it says: citizens have the right to keep and bear arms. The states-rights view currently prevails in federal case law, but the individual-rights view is probably closer to the framers' intent. A reasonable restatement of the amendment might go something like this: "Since we as a nation have found it necessary to organize citizen militias to defend against tyranny and may be compelled to do so again, and since these militias are necessarily composed of volunteers supplying their own weapons, the right of individuals to keep and bear arms shall not be infringed." OK, some gun-control advocates will concede, but that merely means infringed by the federal government. As an article in Mother Jones put it, "The legal precedents are clear: Almost any state or local gun-control action is fine; the Second Amendment does not apply. On the federal level, only laws interfering with state militias are prohibited." This is a crock. The legal precedents are far from clear. They are also pathetically sparse, suggesting a reluctance on the part of the courts and the legal community generally
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by DSBs, and can be used as a marker of DSB formation. Following inhibitor exposure, γH2AX immunocytochemistry was performed in MeWo, SKMel28, UACC62, HT144 and *PTEN*-knockdown MeWo cells. As shown in Figures [6A](#F6){ref-type="fig"}-[6I](#F6){ref-type="fig"}, the percentage of cells with more than six γH2AX foci following inhibitor exposure was significantly higher in *PTEN*-deficient cells compared to *PTEN*-proficient control cells. These data provide additional evidence that *PTEN*-deficient cells accumulate DSBs at an increased rate after exposure to an *APE1* inhibitor relative to *PTEN*-proficient MeWo cells. ![**A.** γH2AX immunocytochemistry following 24 hours inhibitor-1 exposure demonstrates increased foci in PTEN-deficient HT144 cells compared to PTEN-wildtype MeWo. Significantly increased γH2AX foci was observed in PTEN-deficient SkMel28, UACC62 and HT144 cells compared to MeWo cells following 24 hours treatment with inhibitor-1 (B), inhibitor-2 (C), inhibitor-3 (D) or inhibitor-4 (E). Similar significantly increased γH2AX foci was observed in PTEN knockdown (KD) MeWo cells compared to control MeWo cells following 24 hours treatment with inhibitor-1 (F), inhibitor-2 (G), inhibitor-3 (H) or inhibitor-4 (I). \* p\<0.05, \*\* p\<0.01, \*\*\* p\<0.001, compared to MeWo (PTEN-wildtype).](oncotarget-05-3273-g006){#F6} DSB accumulation activates a complex cell cycle checkpoint response that may result in eventual induction of apoptosis. Apoptosis detection by FITC-annexin V flow cytometric analysis was therefore performed in MeWo, SKMel28, UACC62, HT144 and *PTEN*-knockdown MeWo cells following exposure to inhibitor 1, inhibitor 2, inhibitor 3, or inhibitor 4 for 24 or 48 hours. As shown in Figure [7A](#F7){ref-type="fig"}-[7I](#F7){ref-type="fig"}, the percentage of cells undergoing apoptosis following *APE1* inhibitor exposure was significantly higher in *PTEN*-deficient cells in comparison to *PTEN*-proficient MeWo cells. ![**A.** Apoptosis detection by FITC-annexin V flow cytometric analysis demonstrates an increased apoptotic fraction in HT144 following 48 hours exposure to inhibitor-1, as observed by increased FITC-Annexin V staining in upper and lower right quadrants. Significantly increased apoptotic fraction was observed in PTEN-deficient SkMel28, UACC62 and HT144 cells compared to MeWo cells following 48 hours treatment with indicated concentrations of inhibitor-1 (B), inhibitor-2 (C), inhibitor-3 (D) or inhibitor-4 (E). Similar significantly increased apoptotic fraction was observed in PTEN knockdown (KD) MeWo cells compared to control MeWo cells following 48 hours treatment with inhibitor-1 (F), inhibitor-2 (G), inhibitor-3 (H) or inhibitor-4 (I). \* p\<0.05, \*\* p\<0.01, \*\*\* p\<0.001, compared to MeWo (PTEN-wildtype).](oncotarget-05-3273-g007){#F7} Taken together, these functional studies provide compelling evidence that *APE1* inhibition induces a synthetic lethal response in *PTEN*-deficient cells by causing accumulation of abasic sites and subsequent strand breaks, and ultimately the induction of apoptosis. DISCUSSION {#s3} ========== *PTEN* is a key regulator of the anti-apoptotic PI3K/Akt pathway \[[@R15]\], and emerging evidence suggests a role in DNA repair \[[@R19]-[@R21]\]. The role of *PTEN* in the regulation of *RAD51* remains controversial \[[@R24]\]. However, a number of recent studies provide compelling evidence that nuclear *PTEN* may have essential roles in DNA repair \[[@R40], [@R41]\], and that *PTEN* deficiency may be targeted in a synthetic lethality approach by inhibitors of SSBR \[[@R24]\]. Our primary hypothesis is that this synthetic lethality approach may be applied to *PTEN*-deficient melanomas using BER inhibitors such as those targeting *APE1*. We initially investigated the clinicopathological significance of *PTEN* mRNA and *APE1* mRNA in melanoma. Low *PTEN* was associated with poor survival overall but the effect was absent in *BRAF* and *NRAS-*mutated tumours, and only statistically significant in tumours without *BRAF* or *NRAS* mutations. This may be related to the complex tumour-suppressing function of *PTEN*, including its roles as a negative regulator of the anti-apoptotic PI3K/Akt pathway and in DNA repair regulation. That the influence of *PTEN* expression on prognosis was more pronounced in tumours without *BRAF* or NRAS mutations is a new observation, and suggests that *PTEN* loss may be a key biomarker in *BRAF*-wildtype tumours. Taken together, the clinical data are consistent with pre-clinical study that implicates *PTEN* loss in melanoma progression \[[@R26]\]; however, the relatively small patient numbers in the various subgroups is a limitation of our study. Our finding that high *APE1* mRNA is associated with poor survival in melanoma is supported by previous studies \[[@R42]\] and provides additional evidence for targeting *APE1* in melanoma. The success of PARP inhibitors in BRCA-deficient breast and ovarian tumours \[[@R13], [@R14]\] implies that a synthetic lethality approach may be an attractive strategy in melanomas with DSB repair deficiency. *PTEN*-deficient melanoma cells with defective DSB repair may be reliant upon BER as a frontline defence to prevent damage accumulation, replication fork collapse, DSB formation and consequent cell death. Thus, blockade of BER through *APE1* inhibition could lead to synthetic lethality in *PTEN*-deficient cells. To test this hypothesis, we first profiled *PTEN*-deficient and PTEN-proficient melanoma cells for DNA repair factor expression, finding that expression of several genes involved in HR was impaired at protein and mRNA level in *PTEN*-deficient cells. In addition we observed downregulation of genes involved in NHEJ, NER, MMR and MGMT. Given the role of *PTEN* in the regulation of HR expression as well as in HR recruitment to sites of DNA damage \[[@R19]-[@R21]\], it is perhaps not surprising that genomic instability in *PTEN*-null cells may, over a period of time, eventually lead to acquisition of new defects in other DNA repair pathways. Recent studies that positively link *PTEN* with NER \[[@R43]\], MMR \[[@R44]\], and MGMT expression \[[@R45]\] suggests that such a mechanism may be operating in cells, but detailed mechanistic studies are required to confirm this hypothesis. An interesting observation across *PTEN*-deficient cell lines was the loss of BRCA1 protein expression, consistent with previous evidence in UACC62 melanoma cells (<http://cancer.sanger.ac.uk/cancergenome/projects/cosmic/>). This observation is also consistent with a recent study in breast cancer, wherein high frequency of *PTEN* loss was observed in BRCA1-associated breast tumours \[[@R46]\]. In a separate study, *PTEN* loss was found to be a predictor of BRCA1 germ-line mutations in women with early onset breast cancer \[[@R47]\]. Taken together, this evidence suggests a possible functional link between *PTEN* and BRCA1 in melanomas. These observations, however, require detailed mechanistic studies to confirm functional interactions between *PTEN* and BRCA1. *PTEN*-deficient melanoma cells were shown in the current study to be sensitive to *APE1* inhibitors. Similar hypersensitivity observed following exposure to the PARP inhibitor NU1025 is consistent with previous observations using *PTEN*-deficient colorectal cells \[[@R24]\]. We have concluded that the interrelationship between BER and *PTEN* may be a valid therapeutic target in melanoma for the following reasons: a) *PTEN*-deficient cells are sensitive to *APE1* repair domain inhibitors; b) *PTEN*-deficient cells are sensitive to methoxyamine, an indirect inhibitor of *APE1*; c) *PTEN*-deficient cells are sensitive to the PARP inhibitor NU1025; and d) upon *APE1* inhibitor treatment, *PTEN*-deficient cells accumulate DNA DSBs, resulting in the induction of apoptosis. It should be noted that the observed level of apoptosis in *PTEN*-deficient cells following inhibitor exposure is lower than may be predicted from survival analyses using clonogenic assays. Although apoptotic cell accumulation may occur over a period of time following chronic exposure to *APE1* inhibitor, another possible explanation is'synthetic sickness', a synthetic lethal-type relationship wherein the overall outcome is reduced fitness rather than cellular lethality \[[@R48]\]. Accumulation of DNA damage, including specific DSB accumulation, has been associated with the induction of cellular senescence \[[@R49]\]. More recently, *PTEN* loss has also been shown to induce a senescent phenotype \[[@R50]\]. Therefore we speculate that DSB accumulation in *PTEN*-deficient cells following *APE1* inhibition, besides induction of apoptosis, may also drive the cell population into senescence, contributing to reduced clonogenicity. Although further study is required to assess for definitive evidence of senescence induction in this setting, our data raise the intriguing possibility of a
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both $\phi$ and $-\phi$ lie in $\S(G)$, then $G$ is residually a torsion-free solvable group, in particular $G$ is residually $\GG$. The criterion from Lemma \[lem:zbyfree\] applies to the example provided in Section \[section:example\]. Indeed, the homomorphism $\phi\colon G_\pi\to \Z$ defined by $\phi(x)=2$ and $\phi(y)=1$ has the property that $\phi$ pairs maximally with the marked vertex $(-1,-1)$ and $-\phi$ pairs maximally with the marked vertex $(0,-1)$. It follows from Theorem \[mainthm\] that both $\phi$ and $-\phi$ represent elements in $\S(G)$. Let $G$ be a group which admits a $(2,1)$–presentation $\pi$ and suppose $\phi\in \hom(G,\R)$ is a homomorphism such that both $\phi$ and $-\phi$ represent elements in $\S(G)$. It follows from the openness of $\S(G)$ that without loss of generality we can assume that $\phi$ takes values in $\Z$, i.e. that $\phi\in \hom(G,\Z)$. Recall, see Section \[section:bns\], that the existence of such a $\phi$ implies that $\ker(\phi)$ is a finitely generated group. Since $G$ admits a $(2,1)$–presentation it follows from [@Brn87 p. 487], see also [@Bi07 Corollary B], that $\ker(\phi)$ is a free group. This implies that $G$ is isomorphic to a semidirect product $\Z\ltimes F$ where $F$ is a free group. We then consider the filtration $$G\supset F\supset F^{(1)}\supset F^{(2)}\supset \dots$$ where $F^{(n)}$ denotes the $n$-th group in the derived series of $F$. Each successive quotient is a free abelian group. Also note that each $F^{(n)}$ is characteristic in $F$ and it is thus a normal subgroup of $G$. It follows that each quotient $G/F^{(i)}$ is a torsion-free solvable group. Now the lemma follows from the well-known fact that $\cap F^{(i)}$ is trivial. The Ore localization of group rings {#section:ore} ----------------------------------- Let $\G$ be a group which lies in $\GG$. It follows from [@KLM88 Theorem 1.4] that the group ring $\Z[\G]$ is a domain, i.e. it has no non-zero element which is a left or right zero-divisor. Since $\G$ is in particular amenable it follows from [@DLMSY03 Corollary 6.3] that $\Z[\G]$ satisfies the Ore condition. This means that for any two non-zero elements $x,y\in \Z[\G]$ there exist non-zero elements $p,q\in \Z[\G]$ such that $xp=yq$. Now we denote by $\K(\G)$ the set of equivalence classes of pairs $(p,q)$ where $p\in \Z[\G]$ and $q\in \Z[\G]\sm \{0\}$. Here we say that two such pairs $(p,q)$ and $(p',q')$ are equivalent if there exist non-zero $x,y\in \Z[\G]$ with $xp=yp'$ and $xq=yq'$. As usual we denote such an equivalence class by $pq^{-1}$. Since $\Z[\G]$ is a domain it follows that the canonical map $\Z[\G]\to \K(\G)$ is injective. By [@Pa77 Section 4.4] we can extend the ring structure on $\Z[\G]$ to a ring structure on $\K(\G)$, and with this ring structure, $\K(\G)$ is actually a skew field that contains $\Z[\G]$ as a subring. The Zero-Divisor Conjecture states that for any torsion-free group the group ring $\Z[\G]$ is a domain. If this conjecture holds for all torsion-free amenable groups, then throughout the paper we could work with the class of torsion-free amenable groups instead of torsion-free elementary amenable groups. Non-commutative Reidemeister torsion of presentations ----------------------------------------------------- Let $X$ be a finite CW-complex with $G=\pi_1(X)$. We denote by $\wti{X}$ the universal cover of $X$. Let $\varphi\co G\to \G$ be a homomorphism to a group $\G\in \GG$. The homomorphism $\varphi$ equips $\Z[\G]$ and $\K(\G)$ with the structure of a right $\Z[G]$-module. Following the discussion in Section \[section:twihom\] we can thus consider the chain complexes $C_*^\varphi(X;\Z[\G]):=\Z[\G] \otimes_{\Z[G]} C_*(\wti{X})$ and $C_*^\varphi(X;\K(\G)):=\K(\G) \otimes_{\Z[G]}C_*(\wti{X})$. If $C_*^\varphi(X;\K(\G))$ is not acyclic, then we define the corresponding Reidemeister torsion $\tau(X,\varphi)$ to be zero. Otherwise we pick an ordering of the cells of $X$ and for each cell in $X$ we pick a lift to $\wti{X}$. This turns $C_*^\varphi(X;\K(\G))$ into a chain complex of based $\K(\G)$-left modules. We then define $$\tau(X,\varphi) \in K_1(\K(\G)).$$ to be the Reidemeister torsion of the based chain complex $C_*^\varphi(X;\K(\G))$. (Here, given a ring $R$ the first $K$-group $K_1(R)$ is defined as the abelianization of $\underset{\longrightarrow}{\lim} \gl(n,R)$.) Now we write $\K(\G)^\times =\K(\G)\sm \{0\}$ and we denote by $\K(\G)^\times_{\op{ab}}$ the abelianization of the multiplicative group $\K(\G)^\times$. The Dieudonné determinant, see [@Ro94], gives rise to an isomorphism $K_1(\K(\G))\to \K(\G)^\times_{\op{ab}}$ which we will use to identify these two groups. The invariant $\tau(X,\varphi)\in \K(\G)^\times$ is well-defined up to multiplication by an element of the form $\pm g$ with $g\in \G$. Furthermore this invariant only depends on the homeomorphism type of $X$ and the choice of $\varphi$. We refer to [@Tu01; @Fr07; @FH07] for details and more precise references. Given an oriented $m$-component link $L\subset S^3$ we denote by $X_L=S^3\sm \nu L$ the exterior of $L$, i.e. the complement of an open tubular neighborhood $\nu L$ of $L$. We equip $X_L$ with a CW-structure. We denote by $T$ the multiplicative free abelian group generated by $t_1,\dots,t_m$. Furthermore we denote by $\varphi\co \pi_1(X_L)\to T$ the canonical epimorphism given by sending the $i$-th oriented meridian to $t_i$. Finally we denote by $\Delta_L(t_1,\dots,t_m)$ the multivariable Alexander polynomial of $L$. It follows from [@Tu01] that $$\tau(X_L,\varphi)=\left\{ \ba{ll} \frac{\Delta_L(t_1)}{t_1-1},&\mbox{if $L$ has one component}, \\ \Delta_L(t_1,\dots,t_m),&\mbox{if $L$ has more than one component.}\ea \right.$$ Thus the invariant $\tau(X_L,\varphi)$ for admissible homomorphisms to non-abelian groups can be viewed as a non-commutative generalization of the Alexander polynomial of a link. The first such invariants were introduced in [@Coc04] for knots, in [@Ha05] for general 3–manifolds and in [@LM06; @LM08] for plane algebraic curves. In the following, given a presentation $\pi$ and a homomorphism $\varphi\co G_\pi\to \G$ to a group in $\GG$ we write $$\tau(\pi,\varphi)=\tau(X_\pi,\varphi)$$ where $X_\pi$ is the 2-complex corresponding to the presentation $\pi$. The polytope group ------------------ Let $V$ be a vector space. We denote by $\mathfrak{P}(V)$ the set of all translation-equivalence classes of polytopes in $V$. With the Minkowski sum this becomes an abelian monoid, where the identity element $0$ is given by the polytopes consisting of a single point. It is straightforward to show, see e.g. [@Sc93 Lemma 3.1.8], that $\mfp(V)$ has the cancellation property, i.e. for $\PP,\QQ,\RR\in \mfp(V)$ with $\PP+\QQ=\PP+\RR$ we have $\QQ=\RR$. We denote by $\mfg(
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{{q}{f}\!+\! 2 {u}}{2 {q}} d, \, d \!=\! \cosh \big( {q}\tfrac{ {f}}{2 {u}} \big) \nonumber, $$ which has the eigenvalues $$\begin{aligned} \tilde{\lambda}_k \!= \! - \tfrac{2 \Gamma d \; \sin^2 \! \big( \tfrac{k \pi}{{q}} \big) } {{q}} \! \bigg[ 2 {u}\!+\! {\mathrm{i}}{f}{q}\cot \big( \tfrac{k \pi}{{q}} \big) \! \bigg] \!, \, k=0,1,\ldots,{q}\!-\! 1 . \nonumber\end{aligned}$$ We note that for all ${q}$, ${\operatorname{Re}}[\tilde{\lambda}_k ] \geq \!0 \; \forall k$, such that the real parts of all perturbed eigenvalues, $ {\operatorname{Re}}[ \lambda_k ] + \delta {\beta}\, {\operatorname{Re}}[ \tilde{\lambda}_k ] $, change their sign at the critical point from negative ($\delta {\beta}< 0$) to positive values ($\delta {\beta}> 0$) or remain zero. Thus Eq. indeed characterizes the critical point that destabilizes the symmetric fixed point. If the system is at equilibrium, ${f}= 0$, the real parts of the eigenvalues of the linear stability matrix evaluated at the critical point change their sign or remain zero while the imaginary parts are identically zero corresponding to a saddle-node bifurcation that degenerates the single symmetric fixed point into multiple fixed points. In the out-of-equilibrium scenario, ${f}\neq 0$, the real parts of the eigenvalues of the linearized Jacobian evaluated at the critical temperature change their sign or remain zero while the imaginary parts remain finite implying a Hopf-bifurcation that degenerates the symmetric fixed point into a limit cycle. Equation states that the uniform probability distribution can be observed over a larger range of temperatures as ${q}$ increases. The uniform distribution, however, removes the interactions from the dynamics \[cf. Eq. \]. Hence for repulsive interactions the mean-field system is noninteracting as well as for attractive interactions at temperatures above the first critical temperature that approaches zero as ${q}$ becomes large. In the following we consider attractive interactions (${u}=-1$) if not explicitly stated otherwise. To infer the stability of the limit cycles, an analysis of the normal form of the Hopf bifurcation and the computation of the first Lyapunov coefficient would be required [@kuznetsov1998], which for ${q}> 3$ renders analytic progress difficult. A numerical analysis in Fig. \[fig:dynamics\] depicting in a parametric ${\mathcal{P}}_1-{\mathcal{P}}_2$ plot the dynamics of the ${q}$-model (${q}=3,4,5,6$) motivates the following conjecture: If ${q}$ is even like in panels b) and d), the Hopf bifurcation occurs subcritical, [*i.e.* ]{}the limit cycle is unstable and degenerates into ${q}$ asymmetric stable fixed points, hence there is only one phase transition at ${\beta}_c$. Conversely, if ${q}$ is odd, like in panels a) and c), the Hopf-bifurcation occurs supercritical, [*i.e.* ]{}the symmetric fixed point degenerates at ${\beta}_{c_1}$ into a stable limit cycle. Physically, a limit cycle in the ${q}$-dimensional probability space means that the units tend to undergo the same transition together at a given time, i.e. they synchronize. Since the low-temperature limit in Eq. is also satisfied for odd ${q}$, there is a second critical point ${\beta}_{c_2}$ at which the limit cycle degenerates via an infinite-period bifurcation [@keener1981siam] into ${q}$ asymmetric stable fixed points. In both cases, the multiple fixed points are related to each other by permutations of their coordinates in the ${q}$-dimensional probability space. For decreasing temperatures these fixed points move towards the respective energy ground states in Eq.. Thus, we have demonstrated that there are two classes of universal phenomenology: For all ${q}$ the high-temperature (low-temperature) regime is characterized by a single (multiple) (a)symmetric stable fixed point(s), while only for odd ${q}$ there is also an intermediate phase exhibiting stable oscillations. This universality is robust to slight changes of the state energies $\epsilon_i$. For large changes, the critical phenomena vanish and there is a single stable fixed point at all temperatures. We furthermore emphasize that for sufficiently high-dimensional lattices and large system sizes, finite-range interactions will also generate the above phenomenology as discussed in Ref. [@herpich2018prx] and explicitly demonstrated in Ref. [@wood2006prl]. The choice of all-to-all interactions however allows to analytically characterize the universal phenomenology. ![Parametric plot of the probabilities $ {\mathcal{P}}_{1,2} $ for ${q}=3$ \[panel a)\], ${q}=4$ \[panel b)\], ${q}=5$ \[panel c)\] and ${q}=6$ \[panel d)\] for different temperatures ${\beta}$. The orange-shaded spheres indicate the ${q}$ asymmetric fixed points and the symmetric fixed point is represented by the red closed circle. In all plots the initial condition ${\mathcal{P}}_1(0)=1$ is used and the chosen values for the dimensionless parameters read $\Gamma=0.1$ and ${f}=1$. \[fig:dynamics\] ](dynamics) It is natural to consider the large-${q}$ limit where the Potts model becomes the XY model. According to Eq., the phase in which the system exhibits a unique symmetric fixed point and thus is noninteracting exists over an increasing range of temperatures. Hence for exceedingly large ${q}$ the differences between systems with attractive interactions (for both even or odd ${q}$) and repulsive interactions at experimentally meaningful temperatures vanish. Thermodynamics {#sec:thermodynamics} ============== Our thermodynamically consistent formulation of the Potts model \[cf. Eq. \] allows us now to address its nonequilibrium thermodynamic properties. In the appendix \[sec:appendixstochasticthermodynamics\] a thermodynamic description is systematically established. The first law of thermodynamics $$\begin{aligned} {\mathrm{d}}_t \, {\mathcal{E}}= \sum\limits_{i,j} {\mathcal{E}}_{i} \, {\mathcal{V}}_{i j} \, {\mathcal{P}}_{j} = \dot{\mathcal{{Q}}} + \dot{\mathcal{{W}}} ,\end{aligned}$$ states that the rate of change in internal energy ${\mathcal{E}}$ is balanced by heat and work currents, $\dot{{\mathcal{Q}}}$ and $\dot{{\mathcal{W}}}$, hence ensuring energy conservation. Furthermore, the non-negativity of the entropy production $$\begin{aligned} \dot{{\mathcal{S}}}_i = - {\mathrm{d}}_t \sum_j {\mathcal{P}}_j \ln {\mathcal{P}}_j - {\beta}\dot{{\mathcal{Q}}} \geq 0,\end{aligned}$$ constitutes the second law of thermodynamics. Hence, in the long-time limit, the entropy production, up to temperature, is equal to the work, $\dot{{\mathcal{S}}}_i = {\beta}\dot{{\mathcal{W}}}$. We proceed by demonstrating that the bifurcations translate into nonequilibrium phase transitions that can be characterized via the work. Here, the work is dissipative since the mean-field system takes rotational energy, $ \dot{{\mathcal{W}}} >0 $, and dissipates it into the bath in form of heat, $ \dot{{\mathcal{Q}}} <0 $. First, we recall that except for attractive interactions below the critical temperature in Eq. the system behaves like a noninteracting one. The stationary average dissipated work current for a single unit reads $$\begin{aligned} \label{eq:singleunitworkhightemperature} { \langle\dot{{W}}_1^s \rangle }= 2 \Gamma {f}\sinh \left( \frac{{\beta}{f}}{2}\right) \geq 0, \end{aligned}$$ and is independent of the number of states ${q}$. Next, for ${\beta}\gg {\beta}_{c(c_2)} $, the stationary mean-field work current can be approximated as $$\begin{aligned} \dot{{\mathcal{W}}}^s &\approx 2 \Gamma \, {f}\, {\mathrm{e}}^{\frac{{\beta}{u}}{2}} \sinh \left( \tfrac{ {\beta}{f}}{2} \right) = {\mathrm{e}}^{\frac{{\beta}{u}}{2}} \, \langle\dot{{W}}_1^s \rangle. \label{eq:meanfieldunitworklowtemperature}\end{aligned}$$ Hence operating an interacting system in the low-temperatures regime is exponentially less costly in the interaction strength than maintaining a noninteracting one. This can be seen in Fig. \[fig:dissipatedwork\] that depicts the difference between the stationary work current of a single unit ${ \langle\dot{{W}}_1^s \rangle }$ and the asymptotic mean-field work current ${ \overline{{\mathcal{W}}}}$ as a function of ${\beta}$ for different ${q}$. In agreement with Eqs. and, we find that for all ${q}$ the mean-field system is noninteracting at inverse temperatures below the inverse Hopf-bifurcation temperature ${\beta}_{c(c_1)}$ \[Eq. \], while
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ers programme with the opportunity to become permanent at the end of the programme. Babcock aren’t just offering fantastic training and valuable work experience but a genuine opportunity to restart or transfer your career. Babcock recognise that returners often face almost insurmountable barriers to returning to work after a career break, be that because of unconscious bias, a lack of flexibility or flaws in the recruitment process. Their support and commitment to offering returner opportunities and their success in retaining these engineers on a permanent basis shows career break returners just how much they value the skills that they have to offer. The programme is open to men and women in the Bristol and surrounding areas who have taken any length career break, as well as those who wish to transfer sectors but lack the relevant work experience. Babcock are looking for returners with prior experience in the following: Process adherence/ management Data management Large data set analytics Dashboard production Electrical Engineering Mechanical Engineering Naval Architecture Project Management Risk Management Safety Engineer Candidates signing up to the ‘STEM Returners’ programme will join a paid 12-week structured return to work programme which will include soft skills training, technical training and on the job experience, as well as coaching and mentoring support. At the end of the 12 weeks, job offers will be made by Babcock to those who have shown the necessary skills and aptitude to join them. This isn’t just work experience but a genuine opportunity to restart careers within an exciting global organisation. “My group of five returners comprised two women, three men and an age range which went from 23 to just shy of 60. Although many people imagine returners are always women who have had children, my group included a man who had left engineering a decade ago to help bring up his family and another man who had left the industry due to poor health. All of us enjoyed being able to brush up on softer, work-related skills alongside the more technical challenges.” Natalie Desty, Founder of STEM Returners said “We are delighted to be running our third returners programme with Babcock. Babcock are fantastic employers completely committed to the programme which has been demonstrated in how they have supported, developed and retained their STEM Returners.413 Spire Drive, Riverton, Wyoming Property Details 413 Spire Drive, Riverton, Wyoming 82501 - Lots of great updates in this charming 3 bedrooms tri-level home with warm welcoming colors and updated flooring. The home also offers a newer furnace and central air, some newer windows and a beautifully landscaped yard. You will absolutely love your summer entertaining with the beautiful covered deck and patio space. This is a must see property! Check it out at windriverrealty.com Amenities Zip82501 CountyFremont SQFT1764 Bedrooms3 Full baths1.75 StatusActive Purchase TypeActive Property typeSingle Family Zoning typeRESIDENTIAL High schoolRiverton Year built1980 Lot size7700 SewerCity HeatingForced Air Gas CoolingCentral Air Tax amount$1,300.00 Tax year2016 Office ID179 Agent ID495 Agent nameOlivia J Prince MLS® ID20172982 Broker: Wind River Realty Inc Listing Courtesy of Wind River Realty Inc Have Questions? “The entire process was very easy and seamless. All very effortless on my part. They took care of everything and the staff was amazing and went above and beyond their call of duty. ”Saturday, 5 June 2010 [WC2010] Azzurri held by Switzerland World champions Italy were held to a 1-1 draw by fellow FIFA World Cup final tournament hopefuls Switzerland in Geneva, matching the scoreline their Azzurri predecessors recorded in their last warm-up games before their triumphant campaigns in 1982 and 2006. Switzerland coach Ottmar Hitzfeld made two changes following the recent defeat against Costa Rica, with Gelson Fernandes replacing Tranquillo Barnetta and Valon Behrami coming in for Marco Padalino, while Marcello Lippi brought only Gianluca Zambrotta into the team that lost 2-1 to Mexico two days ago. The home side took the lead after only ten minutes when midfielder Gokhan Inler, who plays in Italy with Udinese, dribbled past Riccardo Montolivo and fired in a left-footed effort from 20 metres out. The Azzurri responded only four minutes later, however, courtesy of a precise Fabio Quagliarella header after the Napoli forward's first attempt had rebounded off the head of Philippe Senderos. Switzerland had the best opportunities to score again at the end of the first half, but Zambrotta blocked a Behrami strike with a timely tackle and goalkeeper Federico Marchetti pulled off a good save from Alexander Frei. At the other end it took the intervention of Senderos to deny Giampaolo Pazzini a straightforward header from Christian Maggio's right-wing cross. Both sides made several changes during the second half and the tempo of the game dropped, with fewer openings coming at either end. That said, the hosts still went close in added time through substitutes Hakan Yakin and Xherdan Shaqiri. They begin their World Cup bid against European champions Spain in Group H on 16 June, two days after Italy face Paraguay in Group F. The Azzurri squad will now have two days of rest before gathering again in Milan on Tuesday evening to leave for South Africa. Italian-Calcio Blog recognises all copyrights contained. Where possible we acknowledge the copyright holder. If you own copyright to an article/image and object to its presence, contact the blog immediately using the link at the top of this page. While we make every effort to ensure that the factual content of this blog is accurate, we cannot take any responsibility nor be held accountable for any factual errors published.Canadian Residents US Residents Are you ready for your trip? As you are making non-refundable payments towards your vacation, we want to draw your attention to the importance of travel insurance. Travel insurance is essential anytime you travel outside your home province/state or internationally. There are many unforeseen circumstances that could influence this trip. No one takes a trip assuming the worst. But events happen, even to the well-prepared travelers: You may have to cancel your trip at the last minute to tend to a family emergency. You may need medical assistance when you’re away. Your baggage may go missing, or there may be damage to your personal property. A volcanoe may be erupting in Indonesia, or Iceland and you may not be able come home on your original date. You just never know. But should something happen, it's good to know there is a company you can rely on for affordable coverage and 24-hour assistance. Fly & Sea Dive Adventures is an authorized seller of Manulife Travel Insurance for Canadian residents and CSA Travel Protection for US residents. We highly recommend protecting yourself and your trip investment with the appropriate coverage. There are several different plans that can be purchased individually or as part of a package. They are each designed to ensure you travel with confidence and peace of mind. Terms and conditions apply. Coverage only applies to listed covered events. For more details, please see description of coverage in each respective plan.Q: Unclear activity for Top Questions Recently, I posted an answer this question here: Right border missing on search input. After going back to Top questions, I noticed this; The wording here for me is a little unclear. As it is now, it looks like I have "Edited" or "Changed" that question in some way - however, I only posted an answer. Shouldn't this say something like "Answered 57 mins ago..."? This would make it consistent with newly asked questions, which say "Asked x mins ago..." A: You answered the question and then edited your answer about five minutes later, hence "modified". You can also see the timeline view (click toggle format to see timestamps). Your screenshot was taken much later. We mark a question as "modified" when anything happens on the question or answers other than the question being asked or answered. Most changes make the post active and for the statement and time references to be correct we must recognize all actions, not only those on the question. Since you edited, that's what the action reflects. The question was answered 15 minutes before your second edit, meaning that if we'd said "answered 57 minutes ago" it'd be incorrect as the answer was posted 72 minutes prior. Also "modified" is a link, so if you want to see what was modified, click it. # GPAE01, GPAJ01, GPAP01, GPAU01 - PokemonChannelMainDisk [Core] # Values set here will override the main Dolphin settings. [OnLoad] # Add memory patches to be loaded once on boot here. [OnFrame] # Add memory patches to be applied every frame here. [ActionReplay] # Add action replay cheats here. [Video_Hacks] EFB
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that they are less sensitive to variations in $\Delta_{rr}$, and thus to atomic motion. Conclusion \[Conclusion\] ========================= In this paper we have identified a set of logical qubit basis states for a neutral atom decoherence free subspace and a corresponding set of protected universal gates. Numerical simulations demonstrate that the proposed set of gates is much more robust against phase errors than a set of unprotected gates. They are, however, also much more affected by the motion of the atoms in the traps. Therefore, one has to consider what the worst source of decoherence is for a given physical situation and subsequently choose which set of gates to use. Even if the set of protected gates is assessed to be unfavorable, one should still consider using the logical qubit bases states for computations, as information is then protected during storage of the qubits.\ The work presented in this paper naturally leads to further developments. First, we would like to study resource optimised $\emph{DFS}$ encoding. Here, in order to build a reliable $N=2$-qubit register we have merely associated two two-physical-qubit protected cells, but it is clear that for an $N$-qubit quantum memory $\left( N\geq3\right)$ the number of physical qubits required by this straightforward scheme, *i.e.* $2N$ physical qubits, is much larger than actually needed. This new construction of a $\emph{DFS}$ will induce new problems, as regards practical encoding and processing of the information stored in the $\emph{DFS}$, the resolution of which will probably require the use of quantum control techniques, such as nonholonomic control [@NHC]. Moreover, we also plan to extend our results to more general error models as for instance position-dependent errors. Acknowledgements ================ This work was supported by ARO-DTO grant nr. 47949PHQC. 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He succeeds Christine Day, who announced in June that she planned to resign. Chip Wilson said in a recent television interview that some women's bodies "just don't actually work" for Lululemon pants. He also said that thigh rubbing over time will cause the pilling and poor performance of the pants. Lululemon was receiving complaints about the sheerness of some of its pants, which made them see-through at times. Customers also complained of pilling after a few months of wear — or even just a few uses — and about holes and seams coming apart. The retailer pulled its popular yoga pants from store shelves in the spring, blaming problems on a style change and production issues. New pants have since hit stores, but the sheerness complaints have continued, in addition to the new gripes about wear and tear. Wilson did seem to apologize to Lululemon's workers for the criticism his comments received, but didn't retract his original statements. Analysts that follow the company believe Wilson alienated some core customer and potentially opened a door in the lucrative market to rivals like Nike, Under Armour, Athleta and others. Spending on workout clothes jumped 7 percent to $31.6 billion during the 12-month period that ended in August from the same period a year ago. That compares with a 1 percent rise in spending for other clothing to about $169.2 billion. The Canadian company named lead director Michael Casey as chairman. Wilson will resign before the company's annual meeting in June, at which point Casey will assume the role. Wilson will still have a seat on the board. Laurent Potdevin, the new CEO, most recently served as president of Toms Shoes. Before that, he spent more than 15 years at snowboard company Burton Snowboards in various positions, and as CEO from 2005 to 2010. Potdevin is expected to take over in January. He will also become a board member at that time. Day is anticipated to stay with Lululemon through the end of its fiscal year to help with the transition. Shares of Lululemon Athletica Inc. gained $2.06, or nearly 3 percent, to $72.40 in premarket trading on Tuesday. For the year to date, the shares are down 8 percent.literacy (and assistive technology) "TELL ME A STORY" STORYTELLING CARDS (BILINGUAL)For parents and teachers: have fun building oral language, listening comprehension, and story mapping with these storystarter prompts. Spanish and English.LITERATE ENVIRONMENT SELF-ASSESSMENT TOOLThis eye-opening self-assessment tool has inspired many small and large changes to teaching environments to promote literacy. Elementary and middle/secondary versions available. (Source: Lipson and Wixson). READING WITH YOUR EARS BLOG POSTAudiobooks are like elevators: critical for people with disabilities, and wonderfully useful for everyone else. This guest post on Vocabulogic outlines how all kinds of audiotext support vocabulary learning. READING WITH YOUR EARS - AND OTHER USES OF TECHNOLOGY TO SUPPORT VOCABULARYEveryday technology and assistive technology open up new strategies for vocabulary teaching and learning. This article in the summer 2015 issue of Perspectives is only available to International Dyslexia Association members until October, when it will be available in the archives. inclusion, universal design and differentiated instruction INCLUSIVE PRACTICES TIPSHEETSQuick, readable summaries and checklists of strengths-based approaches, primarily aimed at after-school programs but easily applied in other settings. Written by Alexis Filippini for the Specials Needs Inclusion Project. STUDENT-TEACHER DIALOGUE: FOSTERING SELF-ADVOCACY AND COMMUNICATIONThis dialogue flow chart was developed to support secondary students in navigating conversations with teachers about accommodations or learning styles. INCLUSIVE STORYTIME: HOW TO START ONE AT YOUR LIBRARYThis "cheat sheet" was developed in partnership with the San Francisco Public Library's Mission
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Suppose q = 5*y - 209995, -b*q + 2*y - 551539 - 78459 = 0. Round q to the nearest 100000. -200000 Let m = 40.0565 - 1.0483. Let j = -31 - 8. Let f = j + m. What is f rounded to 3 dps? 0.008 Let g = 221599408.9999926 - 221599326. Let r = g + -83. What is r rounded to six dps? -0.000007 Suppose 2*q - 10 = -2*g, 0*g - 4*g + 23 = 5*q. Suppose 4*b + 24 = q*b + 4*f, b = 3*f - 19. Let o be b/(-18) - 2522/9. Round o to the nearest 100. -300 Let i(m) = 19*m**3 - 3*m**2 - 3*m + 13. Let w be i(3). Round w to the nearest 1000. 0 Let a = -74 + 107. Let l = -33.0043 + a. Round l to three decimal places. -0.004 Let y(j) = -j + 1. Let c(d) = -12450*d + 10375. Let k(i) = -4*c(i) + 41500*y(i). Let q be k(10). What is q rounded to the nearest ten thousand? 80000 Let c = 1096 + -1095.9058. Let o = c - 0.084. Round o to 3 dps. 0.01 Let v = -948929 + 948922.00003. Let j = v - -7. Round j to five dps. 0.00003 Let a = 7.92 - -0.08. Let y = 18073331.00000024 + -18073339. Let g = a + y. Round g to 7 dps. 0.0000002 Suppose 240 = -c + 5*c. Suppose 2*i + 2*i + c = 0. Let p be (-1)/5 + (-1500003)/i. Round p to the nearest 100000. 100000 Let y = 29 + -28.905. Let c = -0.3 - -0.4. Let m = y - c. Round m to 3 dps. -0.005 Let u(z) = z - 4. Suppose 0*c + 2*t - 8 = -c, -3*c = 5*t - 23. Let p be u(c). Suppose 0 = -0*k + p*k - 400000. Round k to the nearest one million. 0 Let b = 54.7 + -21.4. Round b to zero decimal places. 33 Let c = 173005 - 413005. What is c rounded to the nearest one hundred thousand? -200000 Let g(r) = -205555*r - 3. Let d be g(-2). Let o = 278893 + d. Round o to the nearest 100000. 700000 Let q = -3.1 - -17.1. Let o = 27 - q. Let t = o + -15.1. What is t rounded to the nearest integer? -2 Let n = -199.137804 - 2041490.972196. Let h = -2041683.50999943 - n. Let y = 6.6 - h. Round y to 7 decimal places. -0.0000006 Let k = -22 + 37. Let c = 14.99999973 - k. What is c rounded to seven decimal places? -0.0000003 Let r = -590471 + 204579. Let c = r - -385891.9000005. Let g = c - -0.1. What is g rounded to seven decimal places? 0.0000005 Suppose -3*p + 42035 = 2*p. Let i = p - 46928. Let y = i - -26921. What is y rounded to the nearest one thousand? -12000 Let d = 5.5 - 5.4899. What is d rounded to 3 decimal places? 0.01 Suppose -4*i - y - 131 = 0, 10 = 2*i - 5*y + 81. What is i rounded to the nearest ten? -30 Let w = 9.13 + -0.13. Let r = 3.1 - w. Let n = r - -5.9097. What is n rounded to three dps? 0.01 Let h = 58280 - 58326.891. Let z = h - -47. What is z rounded to two decimal places? 0.11 Let x(w) = 4*w**2 + 2*w - 1. Let a be x(1). Suppose a*z - 20 = z. Suppose o = 7*j - 2*j - 381, 2*j - 157 = z*o. What is j rounded to the nearest 10? 80 Let w = 20836 - 20854.009. Let m = w - -18. Let n = -0.0090091 - m. Round n to 6 decimal places. -0.000009 Let v = -81728.04 - -81727.72399863. Let s = v - -0.316. Round s to seven dps. -0.0000014 Suppose 2*z - 8 = z + 2*d, 3*z - d = -1. Let o be (-7)/(-14) - 1/z. Let p(u) = -699*u - 1. Let t be p(o). Round t to the nearest one hundred. -700 Let z = 1.39999978 + -1.4. What is z rounded to 7 dps? -0.0000002 Suppose 5*m + 24836 + 4164 = 0. Round m to the nearest one thousand. -6000 Let x = -77919453987331.000091 - -77919304169807. Let g = -149817444 - x. Let w = -80 + g. Round w to five dps. 0.00009 Let v = -16 + 12. Let z be (-5)/20 + (-55601)/v. What is z rounded to the nearest 1000? 14000 Let s = 2203866 - 1243866. Suppose q + 2*q + s = 0. Round q to the nearest 100000. -300000 Let u = -2.76 + 3.755. Let r = -1 + u. Round r to 2 decimal places. -0.01 Let c = -0.1500026 + 0.15. Round c to six decimal places. -0.000003 Suppose -920 = 5*r + 265. Round r to the nearest 10. -240 Let l = -0.194 - -0.131. What is l rounded to 2 decimal places? -0.06 Let g = 504.31543 + -481.315. Let i = -23.09 + 0.09. Let n = g + i. Round n to four decimal places. 0.0004 Let t = -167194589 + 167193003.00018. Let v = t + 1586.2. Let j = v + -0.2. What is j rounded to five dps? 0.00018 Let u = -2.60001 + 2.6. Round u to 6 decimal places. -0.00001 Let q = -341187 - 1378276. Let d = 1719631.9931 + q. Let o = 169 - d. Round o to three decimal places. 0.007 Let c = -393.9721917 + 5155.9821893. Let w = -4762 + c. Let b = -0.01 + w. What is b rounded to 6 decimal places? -0.000002 Let r = -11 - -10.84. What is r rounded to the nearest integer? 0 Let b = -6.7 - -6. Let n = -0.700006 - b. Round n to 5 decimal places. -0.00001 Let i = -17.36 + 21.5. Round i to the nearest integer. United Nations Security Council Resolution 1724 United Nations Security Council Resolution 1724, adopted unanimously on November 29, 2006, after recalling previous resolutions on the situation in Somalia, particularly resolutions 733 (1992), 1519 (2003), 1558 (2004), 1587 (2005), 1630 (2006) and 1676 (2006), the Council re-established a group to monitor the arms embargo against the country for a further six months and condemned an increase in the flow of weapons to the country. The text, proposed by Qatar, was adopted as Council members debated another resolution partially lifting the arms embargo in order to allow forces from the Intergovernmental Authority on Development to be deployed in Somalia. Resolution 1725 authorised the latter mission to take place. Observations The Security Council urged Somali leaders to continue political dialogue and for the Transitional Federal Government to continue to
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my own blood pressure readings but it has now been extended to hold the following: Blood pressure Systolic & Diastolic Pulse Weight Cholesterol... Platforms: Windows HealthFix+ is a health care software with which you can track your body features like weight, waist, hip and more. Additionally you can make different calculations like Body Mass Index, Body Fat percentage or Waist to Hip Ratio. This application is basically recommended for home users to follow... Platforms: Windows The FREE gray multi-table Health Care Consumer Questionnaire is a comprehensive medical history form designed to be filled out by the health care consumer prior to a visit with a health care provider. This MedicalTemplate is appropriate for a new patient evaluation or any visit to a health care... Platforms: Windows, Mac, Unix, Linux The FREE colorful table format Health Care Consumer Questionnaire is a comprehensive medical history form designed to be filled out by the health care consumer prior to a visit with a health care provider. This MedicalTemplate is appropriate for a new patient evaluation or any visit to a health... Platforms: Windows, Mac, Unix, Linux Health insurance benefit chmod calculator.. Health insurance information delivered to your browser. If you are concerned with you and your families health, its imperative that you stay up to date with whats going on in the health insurance industry. This chmod calculator makes staying up to date... Platforms: Windows The FREE Pet Health Software tracks your pet's health, so you can keep personal records of of your pet's medical history. If you want to know when your cat or dog had an exam, procedure or shot, you can view that information instantly on your own computer. Pet Health Software is free tool for... Platforms: Windows Health Tip Buddy is a free, easy-to-install web site tool that allows your visitors to sign up for e-mail health tips. The program comes with everything you need, including 26 tips - two a month for a year. You can easily add more tips yourself, manage subscribers, and set the look and feel of... Platforms: Windows, Linux Health insurance authority Firefox toolbar. Health insurance information delivered to your browser. If you are concerned with you and your families health, its imperative that you stay up to date with whats going on in the health insurance industry. This toolbar makes staying up to date with... Platforms: WindowsStaying productive at work isn’t easy. Ploughing through so much work is very tiring, ain’t fun and uninspiring. There is always a deluge of interesting things passing by that distract your attention. A funny video on youtube, a whatsapp message or an interesting tweet. In this battle of focus you wage everyday, how to make sure that we get most out of your day without getting tired? How can we boost your productivity at work? Luckily, you don’t need to worry any longer. You can stay energetic and fresh all day long while you can drastically improve your productivity at work and get more work done on time. So, what follows is every tip, trick, and hack that you can use to stay prolific, get shit done and win the battle for focus. Read on the 37 exclusive tips to stay productive and get shit done. Trust us. You’ll feel better afterwards. KNOW YOUR ENERGY Take a few days thinking about what is your most productive time of day and try to organize your time around them. For instance, if you have a natural dip at 4 pm, may be that’s a good time to do tasks that require a little less brainpower. BE AN EARLY BIRD If you often find yourself rushed and flustered when you get to the office, start getting up 15 minutes earlier. The extra time will give you a chance to read through your work notes for the day so that you can start the day feeling well prepared. CHOOSE A BAD JOB Work through your to-do-list sensibly. Don’t choose all the jobs you like first and leave the bad jobs till last. Instead, try to alternate an enjoyable job with one you don’t feel like doing. DON’T PROCRASTINATE Open your post immediately rather than leaving it in unopened piles. Throw away or recycle anything you don’t need to keep and try to file everything else straight away. Keeping out only what you need to deal with. Aim to look at each piece of paper only once and don’t pile it up. GIVE YOURSELF A BREAK Did you know that 91 million working days a year are lost due to mental ill-health in the UK? Working till you drop isn’t going to do anyone favors in the long run, so make sure you give yourself regular breaks to stay on top of things. MAKE A LIST Before you leave work at night, make a fresh list for the next day and stick it on our screen or desktop or leave it open on your desk. It will stop wasting time the next day and help your head stay clear in the evening. BE REALISTIC If you’re commuting anytime, make sure you allow more time as many accidents are caused by people rushing to their destinations. Planning journeys in advance will make you less stressed. A GOOD POSITION Make sure your chair is comfortable and your lower back is supported, and that you’re not too far from your keyboard. Nothing should feel strained or stretched, especially if you stay in the same position for a while. CLEAN IT UP Invest 5 minutes of time in cleaning up your desk before you leave the office – arriving to a clutter-free desk in the morning will help you start the day on the right note. TELL THE TIME Make sure you have a clock on your desk or prominently displayed on your computer. That way, you’ll be able to monitor how long it takes you to do things so time doesn’t run away with you. GET ELECTRONIC ORGANISER Buy an electronic organizer, or use your phone or blackberry, to serve as your diary, address book and calendar. Using it to remember things like birthdays as well as meetings will free up brain space for more efficient working. CREATE A SYSTEM Spend a few hours making sure your filing system is clear and concise and that it works for you. It’s stressful not to be able to find essential items when you need them. COMMUNICATE WITH STAFF If you’re a manager, don’t get so bogged down in trying to assign tasks that you forget to ask your workers what they want – research has shown that people work best if they enjoy their role, so keep in the loop. GET MOBILE Instead of being stuck in the office, buy a laptop so you can maximize flexibility – get one with a built-in fax facility. TELEPHONE TENNIS Return a call once, leaving a message and telling the person when you are available. Make sure you’re available when you say you will be and you’ll avoid wasting time to-ing and fro-ing with answer messages. EAT LIGHT At lunchtime, make sure you don’t overeat and try to avoid too much caffeine and alcohol which might cause a dip in energy in the afternoon. Keep lunch light and energizing with salads, frail and protein. MULTITASK Jobs that aren’t too critical and don’t require 100% concentration can be joined together to save time; for instance, deleting junk emails, or organizing papers while “on hold” on the phone. KEEP IT BRIEF Try to keep work phone calls brief and to the point. Spend a minute deciding what you want to say beforehand and try not to be distracted. SET A STANDARD To save time when you’re sending emails or letters, try to create standard templates you can use so you don’t have to worry about starting afresh each time.This will help you free up more office time for other tasks. GET OUT AND ABOUT Your office will work more efficiently if everyone has a lunch break. Try to encourage everyone to go out for at least a 10 or 15 minute break to perk them up and keep them going for the rest of the day. BE PREPARED If possible, try to set out your clothes the night before so you don’t rush in the morning. If you take a packed lunch to work, make sure it’s already prepared so you can get out of the door quickly. SOUND OF SILENCE In laboratory experiments, it has been shown that mice who were played irritating noises found it harder to concentrate. Make sure your office is free of audible irritations. FILE IT AWAY Make a scheduled time to do your filing every day so papers don’t get on top of you. It’s an easy job, so right after your lunch break or later in the afternoon is usually a good time to choose. PAIN BEFORE PLEASURE It might be tempting to do all the enjoyable things in your life first, but studies show you’ll actually enjoy your leisure time more if you feel you’ve achieved something beforehand – so work now, play later. GET COMPETITIVE To help keep you all motivated and if you have co-workers who are interested, get them involved in deadline competitions for tasks or see who delivers the best quality product or service within the time. CLEAN OUT Make it a rule
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510, 2238, 273, 2508, 27, 346, 13161, 3, 323, 2197, 13122, 13, 346, 12784, 1177, 3, 323, 34000, 18011, 4793, 18012, 13, 346, 16450, 3, 323, 14242, 18011, 4793, 18012, 13, 390, 346, 46376, 3, 323, 512, 643, 2959, 18012, 11976, 187, 186, 3, 788, 35238, 23454, 6870, 14, 19581, 1381, 50266, 3, 510, 2408, 273, 247, 2959, 3453, 995, 187, 186, 3, 788, 35238, 23454, 6870, 14, 6851, 1381, 50263, 3, 510, 2908, 9801, 323, 247, 2197, 9996, 995, 187, 186, 3, 788, 35238, 23454, 6870, 14, 87, 483, 1381, 50264, 3, 510, 9996, 3453, 3605, 995, 187, 186, 3, 788, 35238, 23454, 6870, 14, 7821, 14503, 13060, 7483, 1381, 346, 2447, 1178, 995, 535, 186, 605, 16912, 36, 7047, 1336, 55, 19, 30936, 1361, 15, 187, 186, 3, 2948, 68, 41282, 87, 19, 283, 14107, 18614, 1381, 50275, 3, 3351, 4124, 247, 1618, 273, 362, 19, 260, 41282, 715, 253, 23138, 15, 9876, 417, 1347, 12820, 327, 253, 15116, 995, 187, 186, 3, 2948, 68, 41282, 87, 19, 14, 5478, 7436, 1381, 346, 510, 4983, 2972, 4898, 323, 436, 1618, 273, 260, 41282, 995, 187, 186, 3, 2948, 68, 41282, 87, 19, 14, 41282, 1381, 50273, 3, 510, 1618, 273, 15442, 14, 36034, 260, 41282, 995, 535, 186, 605, 16912, 36234, 4814, 30936, 1361, 15, 187, 186, 3, 2948, 13552, 2364, 283, 14107, 18614, 1381, 346, 3351, 4124, 247, 411, 3801, 14, 36034, 3055, 2234, 281, 253, 686, 2948, 264, 8, 2395, 17295, 187, 186, 3, 2948, 13552, 2364, 14, 13552, 2364, 1381, 50275, 3, 510, 411, 3801, 14, 36034, 3055, 2234, 995, 187, 186, 3, 2948, 13552, 2364, 14, 1968, 1381, 50273, 3, 2447, 3197, 313, 18265, 320, 440, 1178, 390, 686, 2948, 264, 3401, 995, 187, 186, 3, 2948, 13552, 2364, 14, 373, 5092, 1381, 50274, 3, 2632, 5092, 253, 20022, 313, 17480, 253, 3608, 261, 2972, 13, 390, 11017, 4064, 2972, 10, 323, 18012, 6537, 407, 253, 21117, 2234, 995, 187, 186, 3, 2948, 13552, 2364, 14, 22798, 4064, 1381, 50276, 3, 11144, 1180, 323, 835, 281, 1265, 501, 5092, 432, 995, 535, 186, 605, 16912, 9026, 1361, 15, 187, 186, 3, 2948, 3866, 283, 14107, 18614, 1381, 346, 19206, 247, 41582, 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187, 186, 3, 24706, 9252, 283, 14107, 18614, 1381, 346, 35394, 247, 2173, 3453, 17295, 187, 186, 3, 24706, 9252, 14, 483, 3659, 1381, 50276, 65, 5677, 3659, 313, 249, 830, 346, 10136, 13362, 27, 4663, 2807, 281, 5878, 11976, 535, 186, 605, 5552, 18091, 84, 30936, 1361, 15, 187, 186, 3, 3550, 15793, 84, 283, 14107, 18614, 1381, 50271, 3, 2573, 14364, 36, 11657, 1969, 16548, 247, 13922, 1789, 273, 512, 8553, 285, 616, 40216, 17295, 187, 186, 3, 3550, 15793, 84, 14, 1222, 8259, 1381, 50269, 3, 44831, 1180, 273, 2972, 6583, 569, 2424, 1078, 271, 440, 1033, 290, 3453, 434, 1318, 310, 2908, 275, 253, 6654, 995, 187, 186, 3, 3550, 15793, 84, 283, 6870, 17, 283, 12898, 1381, 50276, 3, 17635, 1789, 342, 2395, 4454, 347, 10149, 285, 1086, 433, 8322, 347, 2193, 995, 187, 186, 3, 3550, 15793, 84, 283, 6870, 17, 283, 2364, 1381, 50275, 3, 510, 2395, 1416, 995, 187, 186, 3, 3550, 15793, 84, 283, 6870, 17, 283, 2877, 1381, 346, 510, 2395, 6654, 21392, 275, 1086, 433, 995, 535, 186, 605, 5552, 18703, 2447, 1033, 290, 30936, 1361, 15, 187, 186, 3, 3550, 4348, 328, 1033, 290, 283, 14107, 18614, 1381, 346, 34551, 247, 13922, 3781, 273, 562, 10801, 7101, 347, 12623, 313, 3113, 5569, 328, 1033, 290, 10, 323, 436, 23138 ]
blocks": "The number of blocks processed", "inforesult-timeoffset": "The time offset", "inforesult-connections": "The number of connected peers", "inforesult-proxy": "The proxy used by the server", "inforesult-difficulty": "The current target difficulty", "inforesult-testnet": "Whether or not server is using testnet", "inforesult-relayfee": "The minimum relay fee for non-free transactions in DCR/KB", "inforesult-errors": "Any current errors", "inforesult-paytxfee": "The fee per kB of the serialized tx size used each time more fee is required for an authored transaction", "inforesult-balance": "The balance of all accounts calculated with one block confirmation", "inforesult-walletversion": "The version of the address manager database", "inforesult-unlocked_until": "Unset", "inforesult-keypoolsize": "Unset", "inforesult-keypoololdest": "Unset", // GetNewAddressCmd help. "getnewaddress--synopsis": "Generates and returns a new payment address.", "getnewaddress-account": "Account name the new address will belong to (default=\"default\")", "getnewaddress-gappolicy": `String defining the policy to use when the BIP0044 gap limit would be violated, may be "error", "ignore", or "wrap"`, "getnewaddress--result0": "The payment address", // GetRawChangeAddressCmd help. "getrawchangeaddress--synopsis": "Generates and returns a new internal payment address for use as a change address in raw transactions.", "getrawchangeaddress-account": "Account name the new internal address will belong to (default=\"default\")", "getrawchangeaddress--result0": "The internal payment address", // GetReceivedByAccountCmd help. "getreceivedbyaccount--synopsis": "Returns the total amount received by addresses of some account, including spent outputs.", "getreceivedbyaccount-account": "Account name to query total received amount for", "getreceivedbyaccount-minconf": "Minimum number of block confirmations required before an output's value is included in the total", "getreceivedbyaccount--result0": "The total received amount valued in decred", // GetReceivedByAddressCmd help. "getreceivedbyaddress--synopsis": "Returns the total amount received by a single address, including spent outputs.", "getreceivedbyaddress-address": "Payment address which received outputs to include in total", "getreceivedbyaddress-minconf": "Minimum number of block confirmations required before an output's value is included in the total", "getreceivedbyaddress--result0": "The total received amount valued in decred", // GetTransactionCmd help. "gettransaction--synopsis": "Returns a JSON object with details regarding a transaction relevant to this wallet.", "gettransaction-txid": "Hash of the transaction to query", "gettransaction-includewatchonly": "Also consider transactions involving watched addresses", // HelpCmd help. "help--synopsis": "Returns a list of all commands or help for a specified command.", "help-command": "The command to retrieve help for", "help--condition0": "no command provided", "help--condition1": "command specified", "help--result0": "List of commands", "help--result1": "Help for specified command", // GetTransactionResult help. "gettransactionresult-amount": "The total amount this transaction credits to the wallet, valued in decred", "gettransactionresult-fee": "The total input value minus the total output value, or 0 if 'txid' is not a sent transaction", "gettransactionresult-confirmations": "The number of block confirmations of the transaction", "gettransactionresult-blockhash": "The hash of the block this transaction is mined in, or the empty string if unmined", "gettransactionresult-blockindex": "Unset", "gettransactionresult-blocktime": "The Unix time of the block header this transaction is mined in, or 0 if unmined", "gettransactionresult-txid": "The transaction hash", "gettransactionresult-walletconflicts": "Unset", "gettransactionresult-time": "The earliest Unix time this transaction was known to exist", "gettransactionresult-timereceived": "The earliest Unix time this transaction was known to exist", "gettransactionresult-details": "Additional details for each recorded wallet credit and debit", "gettransactionresult-hex": "The transaction encoded as a hexadecimal string", "gettransactionresult-type": "The type of transaction (regular, ticket, vote, or revocation)", "gettransactionresult-ticketstatus": "Status of ticket (if transaction is a ticket)", // GetTransactionDetailsResult help. "gettransactiondetailsresult-account": "DEPRECATED -- Unset", "gettransactiondetailsresult-address": "The address an output was paid to, or the empty string if the output is nonstandard or this detail is regarding a transaction input", "gettransactiondetailsresult-category": `The kind of detail: "send" for sent transactions, "immature" for immature coinbase outputs, "generate" for mature coinbase outputs, or "recv" for all other received outputs`, "gettransactiondetailsresult-amount": "The amount of a received output", "gettransactiondetailsresult-fee": "The included fee for a sent transaction", "gettransactiondetailsresult-vout": "The transaction output index", "gettransactiondetailsresult-involveswatchonly": "Unset", // ImportCFiltersV2Cmd help. "importcfiltersv2--synopsis": "Imports a list of v2 cfilters into the wallet. Does not perform validation on the filters", "importcfiltersv2-startheight": "The starting block height for this list of cfilters", "importcfiltersv2-filters": "The list of hex-encoded cfilters", // ImportPrivKeyCmd help. "importprivkey--synopsis": "Imports a WIF-encoded private key to the 'imported' account.", "importprivkey-privkey": "The WIF-encoded private key", "importprivkey-label": "Unused (must be unset or 'imported')", "importprivkey-rescan": "Rescan the blockchain (since the genesis block, or scanfrom block) for outputs controlled by the imported key", "importprivkey-scanfrom": "Block number for where to start rescan from", // ImportScript help. "importscript--synopsis": "Import a redeem script.", "importscript-hex": "Hex encoded script to import", "importscript-rescan": "Rescans the blockchain (since the genesis block, or scanfrom block) for outputs controlled by the imported key", "importscript-scanfrom": "Block number for where to start rescan from", // ImportXpub help. "importxpub--synopsis": "Import a HD extended public key as a new account.", "importxpub-name": "Name of new account", "importxpub-xpub": "Extended public key", // MixAccount help. "mixaccount--synopsis": "Mix all outputs of an account.", "mixaccount-account": "Account to mix", // MixOutput help. "mixoutput--synopsis": "Mix a specific output.", "mixoutput-outpoint": `Outpoint (in form "txhash:index") to mix`, // ListAccountsCmd help. "listaccounts--synopsis": "DEPRECATED -- Returns a JSON object of all accounts and their balances.", "listaccounts-minconf": "Minimum number of block confirmations required before an unspent output's value is included in the balance", "listaccounts--result0--desc": "JSON object with account names as keys and decred amounts as values", "listaccounts--result0--key": "The account name", "listaccounts--result0--value": "The account balance valued in decred", // ListLockUnspentCmd help. "listlockunspent--synopsis": "Returns a JSON array of outpoints marked as locked (with lockunspent) for this wallet
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a political mess" and "madness". It was a rare moment of sanity in the whole sorry process.Details:Total Quantity: 140. Take all price: $840 ($6 each), Lot of 6: $45 ($7.50 each). Made of 1/16th inch thick hardboard, this wall mounted reindeer head wall hanging is first a puzzle, then a decor item. The head assembles easily, using the included instructions, and mounts to your wall with a single nail or screw. It measures 22 inches tall, 21 inches wide and 16 inches deep when assembled. Seller Sku# MU-2SHR41-60-002WHblockbuster We at TreeHugger are a huge fans of the Product Service System, better known to some as PSS. Though the name is easy to trip over, the concept is brilliant: rather than buying everything you need outright, you can essentially “lease” or “rent” a product, deriving benefit from its service but not retaining ownership. That…Kogun Kogun is the first album recorded by the Los Angeles-based Toshiko Akiyoshi – Lew Tabackin Big Band. It was released in Japan by Victor in 1974 and received the Swing Journal Silver Disk prize for that year. It was later released on RCA Victor in the USA and elsewhere and received a 1979 Grammy nomination for Best Jazz Instrumental Performance by a Big Band. All tracks from this album are also included on the 2008 Mosaic 3 CD compilation, Mosaic Select: Toshiko Akiyoshi - Lew Tabackin Big Band. Track listing All songs composed and arranged by Toshiko Akiyoshi LP side A "Elegy" – 9:13 "Memory" – 10:24 LP side B "Kogun" – 6:49 "American Ballad" – 5:49 "Henpecked Old Man" – 9:08 Personnel Toshiko Akiyoshi – piano Lew Tabackin – tenor saxophone Tom Peterson – tenor saxophone Dick Spencer – alto saxophone Gary Foster – alto saxophone Bill Perkins – baritone saxophone Bobby Shew – trumpet John Madrid – trumpet Don Rader – trumpet Mike Price – trumpet Charles Loper – trombone Jim Sawyer – trombone Britt Woodman – trombone Phil Teele – bass trombone Gene Cherico – bass Peter Donald – drums Other Scott Ellsworth – voice (on "Memory") References / external links RCA Victor Records RVC RCA-6246 [ Allmusic] 1979 Grammy award nomination (Metrolyrics.com link) 1974 Swing Journal (Japanese jazz magazine) Silver Disk award (Japanese link) Category:Toshiko Akiyoshi – Lew Tabackin Big Band albums Category:1974 albumsA festering four-year war, crippling sanctions, threats to maritime oil trade and a US naval battlegroup steaming for the Persian Gulf. Such developments were troubling enough, before two Saudi tankers were reportedly sabotaged off the UAE coast on Sunday – a development set to ratchet tensions between Tehran and Washington to new and combustible highs. With Riyadh claiming significant hull damage to its ships and the UAE claiming the damage was done inside its territorial waters, what last week was a looming standoff is now a real-time crisis with potent implications for both global energy security and regional stability. Throughout Donald Trump’s presidency, staring down Iran has been top of the agenda among many to have passed through the revolving door of his inner circle. For the current uber-hawks, the US secretary of state, Mike Pompeo, and the national security adviser, John Bolton, there has hardly been a higher calling. Both have been pivotal in focusing Trump on Iran, and imposing new comprehensive sanctions on its economy. And both drove the bellicose rhetoric that last week spelled out the same scenario to which the region awoke on Monday. According to Riyadh, one of the “sabotaged” tankers was en route to a Saudi port to upload oil to be exported to the US. Stopping such a shipment would be consistent with an act of revenge for crippling Iranian exports and for making good on threats to disrupt global energy routes – although on Monday Iran vehemently denied playing a role. Bolton’s prediction of a “credible threat” from Iran, or its proxies, to the oil interests of Washington, or its allies, however looks prophetic in the royal courts of the Gulf. And what regional officials are calling a “terrorist attack” is certain to similarly energise a White House that has at times appeared to be itching for a confrontation with a foe it now faces in most corners of the Middle East. Iran has steadily become the sum of all fears in the eyes of the US and its regional allies; its creeping influence across the Arab world, belligerence towards Israel and perceived readiness to act on its threats to a decades old regional order, which – not without irony – was upended by the US invasion of Iraq. Trump’s backers ignore the Bush administration’s intervention, blaming instead Barack Obama’s pivot towards Iran and his signature nuclear deal for kickstarting Iran’s adventurism. While Obama’s gestures were hardly seen in Tehran as trust-building measures and did nothing to slow a regional consolidation, Iran’s ascendancy started before him and has continued since. Members of the Iranian Revolutionary Guard arrive for a ceremony marking the 40th anniversary of the 1979 Islamic Revolution in February 2019. Photograph: Abedin Taherkenareh/EPA Tehran’s view has been rather different. It views the US as a capricious actor whose presence and interventions has destabilised the region for decades. In Trump’s America, it sees a player with the same sort of ideological zeal that it is accused of wielding itself. A self appointed global sheriff not worthy of the badge and to whom it can never bow. The ill-fated reality of 2003 gave Tehran a bridgehead in Iraq and a springboard into Syria that, nearly eight years into the civil war, has brought the Iranian Revolutionary Guards Corps to within striking distance of Israel’s north. Iran’s proxies have also helped weigh down Saudi Arabia in Yemen, lay the foundations for a parallel state in Iraq and energise a still rumbling opposition movement in Shia-majority Bahrain. The loaded geopolitics have rarely strayed far from oil though. And with Iran’s embattled economy dependent on oil exports and the US once again enthusiastic for Saudi crude, a flashpoint in the Strait of Hormuz, through which 35% of the world’s oil is shipped, has long been likely. Tensions have been boiling since the Trump administration’s decision to lift sanctions waivers from eight countries that import Iranian oil. The stated goal of this was to collapse Iran’s exports to “zero”. Exports had already taken a hit when Trump pulled out of the nuclear deal signed by his predecessor last November – partly in the hope of renegotiating a better deal. Ever since, Iran has prevaricated on its own commitment to a multilateral pact, which delivered revenue streams and global legitimacy, albeit briefly. Last week, Iran said it would no longer honour parts of the deal and had no interest in discussing a revised version. Several things are abundantly clear though; sanctions, including banking restrictions, are hitting the Iranian economy hard, limiting its capacity to sustain its people, or allies, including Hezbollah in Lebanon, where fighters have taken substantial pay cuts in recent months. More importantly though, Iran cannot let itself be seen to capitulate to the US moves. To do so would risk far more than its post-2003 gains. Washington appears to be betting on just such a surrender, and has pushed brinkmanship to its limits. On Monday, it warned US citizens in Iraq and elsewhere in the region to be vigilant. The risks of miscalculation on either side are higher than they’ve been in the past 16 years.Uncommon Business is a blog about people who make money online selling unusual, strange and sometimes bizarre things or provide curious services. This isn’t “One Hundred And One Ideas For Your Homebased Business” – only real, working businesses with URLs provided, so you can do further investigation on your own. And if you do own an unusual web business, make sure you submit your story to us. SHLD Monday, January 25, 2010 It's pancakes. In a can. It's made $15 million. In 2001, Sean O'Connor was a co-owner of Thee Parkside, a San Francisco club that served up punk bands alongside yak burgers and bear-meat chili. When the dot-coms collapsed, he pared down the menu to focus on cheap, creative snacks. During an experiment with whipped cream canisters and funnel cake -- a project that failed miserably -- he stumbled on a better idea: putting pancake mix in pressurized cans for quick and easy breakfasts. By 2005 O'Connor, now 38, had left the restaurant business and filed patents for Batter Blaster, an organic pancake-and-waffle mix in a pressurized can with a point-and-shoot nozzle. Through word of mouth, social networking and publicity stunts -- traveling 180,000 miles in an Airstream trailer to visit county fairs; rallying a team to cook 76,382
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-0030){ref-type="ref"} Thus, the corpus callosum may be a principal site of myelin dysfunction and axonal injury that is vulnerable to oxidative stress in MSA. Several studies have reported sex differences in the neuroprotective effect of urate in various neurodegenerative disorders. In Parkinson's disease, high urate levels have consistently been associated with lower risk among men, while the association was weaker and inconsistent among women.[^31^](#acn351073-bib-0031){ref-type="ref"}, [^32^](#acn351073-bib-0032){ref-type="ref"} Urate levels also predicted survival in men with amyotrophic lateral sclerosis.[^33^](#acn351073-bib-0033){ref-type="ref"} Similarly, modulatory effect of urate on the risk and disease progression in MSA has been observed in male patients.[^9^](#acn351073-bib-0009){ref-type="ref"}, [^10^](#acn351073-bib-0010){ref-type="ref"} However, in this study, the association between serum urate levels and white matter disintegrity was observed in both male and female patients without significant urate by sex interaction, in spite of difference in the mean serum urate levels between sexes. These results imply that urate may be protective against white matter degeneration in MSA patients irrespective of sex. Because serum urate concentrations were typically higher in men than in women, the antioxidative effects of urate seems more likely to be seen in men.. However, some studies have reported an inverse association between urate and Parkinson's disease risk even in female patients,[^31^](#acn351073-bib-0031){ref-type="ref"}, [^34^](#acn351073-bib-0034){ref-type="ref"} which is consistent with our results. Since estrogen has an inverse correlation with serum urate levels[^35^](#acn351073-bib-0035){ref-type="ref"} and a protective effect on neurodegeneration and neuroinflammation,[^36^](#acn351073-bib-0036){ref-type="ref"}, [^37^](#acn351073-bib-0037){ref-type="ref"} it is inappropriate to apply the antioxidant effect of absolute serum urate levels equally to both sexes. Future studies focusing on sex‐specific antioxidant effect of urate in MSA are warranted. Subgroup analysis according to the clinical subtypes of MSA revealed that the correlation between urate and white matter degeneration was primarily observed in MSA patients with predominant cerebellar type. Despite the common pathological findings of oligodendroglial cytoplasmic inclusions, MSA‐P and MSA‐C are different in terms of clinical, neuropathological, and imaging characteristics.[^1^](#acn351073-bib-0001){ref-type="ref"} Although the mechanism that determines the clinically different subtypes in MSA remains largely unknown, we can infer from this study that oxidative stress may play a pivotal role in the pathogenesis of phenotypic heterogeneity in MSA. This result also has an implication for trial design that targets antioxidation as a disease‐modifying therapy in MSA. Path analysis revealed that white matter disintegrity in cerebellar peduncle mediated the association of serum urate level with disease severity in MSA. Consistent with our results, a previous study has reported that patients with MSA showed a negative correlation between serum urate level and disease severity.[^38^](#acn351073-bib-0038){ref-type="ref"} Imaging studies using DTI have demonstrated that ataxia scale was associated with FA values in cerebellar white matter, middle cerebellar peduncle, and posterior limb of internal capsule and with MD values in cerebellar white matter in MSA‐C.[^6^](#acn351073-bib-0006){ref-type="ref"} These studies suggest that serum urate and white matter disintegrity are closely interacted with disease severity in MSA. Pathological studies have reported that in MSA, there are neuronal loss, deposition of glial cytoplasmic inclusion, and extensive myelin loss in medullo‐ponto‐cerebellar regions, which are interconnected by middle and inferior cerebellar peduncles.[^39^](#acn351073-bib-0039){ref-type="ref"} Considering the important role of oxidative stress in degeneration of oligodendrocyte,[^40^](#acn351073-bib-0040){ref-type="ref"} urate may engage in modulation of MSA‐related white matter degeneration, which in turn, could affect clinical manifestation of MSA. Thus, it is plausible that cerebellar peduncle may be an important anatomical substrate linking oxidative stress and disease severity in MSA. The present study has several limitations. First, the cross‐sectional design limited to identify a causal relationship between serum urate levels and white matter disintegrity. Longitudinal study studies are required to elucidate the protective role of urate in white matter degeneration. Second, there are many risk factors associated with hyperuricemia or white matter integrity that may interfere with the assessment of independent relationship between urate and white matter integrity, such as cognitive function, smoking, diet, body mass index, and renal function. To generalize the results, a larger sample size is required, adjusting a sufficient number of important variables and strictly matching the controls. Third, we recruited MSA patients with varying disease duration and severity. Association of urate and white matter integrity according to disease duration or severity might present a different pattern of the role of urate as an antioxidant as the neurodegeneration progresses. Fourth, pathologic evaluation was not performed in all patients. Such an evaluation may help in studying the definite relationship between serum urate levels and the degree of demyelination or axonal injury. The present study demonstrated that serum urate levels played a pivotal role in microstructural white matter disintegrity and clinical disability in patients with MSA. The results of the present study provide potential evidence that therapy targeting serum urate levels may be a possible candidate for disease‐modifying therapy in MSA. Conflict of Interest {#acn351073-sec-0023} ==================== The authors declare that they have no competing interests. Author Contributions {#acn351073-sec-0024} ==================== H.S.Y., H.K., and P.H.L. contributed to the concept and design of the study. H.S.Y., S.J.C., Y.H.L., H.K., and P.H.L. contributed to the acquisition and analysis of the data. All authors contributed to drafting the text and preparing the figures. Supporting information ====================== ###### **Method S1.** Neuroimaging acquisition. **Method S2.** Processing of DTI data. **Method S3.** Processing of high‐resolution T1‐weighted MR data. **Figure S1.** Group comparison of white matter integrity (A) between MSA patients and normal controls and (B) between male and female MSA patients. **Table S1.** Path analyses of serum urate level or DTI measures for total UMSARS score ###### Click here for additional data file. This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (grant number: NRF‐2019R1A2C2085462). Professional athletes are some of the most confident and competitive people on the planet. They got to where they are through incredible work and an undying belief in themselves. It should therefore come as no surprise to hear Los Angeles Lakers forward Brandon Ingram voice the belief he still has in himself despite an up-and-down career to this point. Ingram told Dave McMenamin of ESPN his sights are set pretty high in terms of his ceiling. “I like to think to the highest, highest. I don’t think it’s unrealistic,” Ingram told ESPN. “I would say my career, career goal would be the best player in this league one day.” Interestingly enough, Lonzo Ball answered a question about where he sees his career ending up, and his response might give a tiny bit of insight into the two players’ differing mentalities. Here’s the thing: As great as it is that Ingram believes in himself and how far that has gotten him to this point, there comes a time where he needs to be a little more realistic. Maybe his age-21 season is a little early for that (hell, I still had dreams at 21), but at some point, Ingram needs to realize that he can have a very successful career and fall short of being the best player in the NBA. This isn’t even necessarily a knock on Ingram, either. That Ingram might never be the best player in the NBA in any given year says as much about the state of the NBA than anything else. The guys who play in this league are insanely good and it seems we’re in one of the most bountiful talent booms the league has ever seen. Not reaching the pinnacle of the professional ranks right now is no failure whatsoever. Where I do worry a little about this response, however, is what it says about how Ingram approaches his development. We’ve already seen him struggle to be productive when he’s off the ball this season at times. What the Lakers need from Ingram is a willingness to accept a supplementary role and be the best he can be at that role. He has seemed to do a slightly better job of that of late (albeit in brief flashes), but the real test for him will come when LeBron James comes back. If the changes he’s shown some
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home was a carriage house for a large farm and estate dating back to the early 1800's, and was converted to a guest house in the 1920's. We are a smoke-free bed & breakfast. We have central air conditioning for extra comfort on hot summer days and a masseuse is available by appointment. The Great Room offers a comfortable place to relax, with a roaring fire on winter evenings; or enjoy those summer nights on the covered verandah Located near Storm King Art Center, West Point, DIA: Beacon, Woodbury Common Premium Outlets, and 1 hour from NYC Great restaurants nearby Accommodations - Events - Meetings Come and enjoy our cozy lodge, converted from an early 1800's post-and-beam barn, and guest cottage in a country setting with gardens, pool and mountain views. Enjoy your intimate wedding at this cozy, country B&B. The Storm King Lodge and Guest Cottage offers a country setting with gardens, pool and mountain views, perfect for your small rehearsal dinner and intimate country wedding, all in the same place. Weddings Enjoy your intimate wedding at this cozy, country B&B. The Storm King Lodge and Guest Cottage offers a country setting with gardens, pool and mountain views, perfect for your small rehearsal dinner and intimate country wedding, all in the same place. No more than 50 guests are recommended. We will network with your wedding planner the quality components necessary to create your perfect wedding, from the rehearsal dinner to reception.Related Suppliers Related Suppliers Featured Research Featured Research Quick Stats Quick Stats You are here Former Genuardi's Employees Buy Zagara's Stores NORRISTOWN, Pa. - Pleasanton, Calif.-based Safeway has sold three of the Zagara's Specialty & Natural Foods stores that were part of its acquisition of Genuardi's Family Markets to three former Genuardi's employees. October 8, 2002, 08:00 pm NORRISTOWN, Pa. - Pleasanton, Calif.-based Safeway has sold three of the Zagara's Specialty & Natural Foods stores that were part of its acquisition of Genuardi's Family Markets to three former Genuardi's employees. Two of the gourmet grocery stores are located in the New Jersey towns of Mount Laurel and Evesham, while the other store is in Glen Mills, Pa. Maryanne Crager, a spokeswoman for Norristown, Pa.-based Genuardi's, told the Burlington County Times the deal will be finalized on Thursday. She declined to reveal the sales price, but said the stores are expected to reopen Monday and will retain the Zagara's name. A fourth Zagara's in Jenkintown, Pa., will be permanently closed, but the date has not been decided, according to the company. Industry observers have said the Zagara's stores were not considered a good fit with Safeway's corporate supermarket strategy and were allegedly losing money even before the chain's acquisition of Genuardi's two years ago. "Zagara's has a truly great format, but the feeling is that it is a much different than Genuardi's," Crager said. "It is a specialty store and the needs of the customers are different. We feel the sale is a plus for the Zagara's customer." The new owners are James DeGillio, Ray Fuentes and Joseph Scarnaty, all who formerly worked at the corporate level at Genuardi's. Fuentes was director of corporate finance, while DeGillio was director of food service. No further information about Scarnaty was immediately available.Q: Javascript form submits to new page -- how can I keep it on the same page? beginner programmer here. Trying to create a very primitive "chat interface", in JSP where I type in some words, they're stored in an array, then, ideally, spit back out on the same page. I've got the code somewhat working, but it loads to a new page. I've tried a number of different things that I read on the net, including trying to add "return false" to my showChats function, trying to change the submit to a button and doing "onclick", but it's still not working, always loads a new page. Any ideas on how to solve this? Thanks in advance. Here's the code: <script> counter = 0; //Array containing initial elements. var chats = []; function show_array(array) { array[counter] = document.getElementById("chatlet").value; for (x = 0; x < array.length; x++){ document.write(array[x] + "<br/>"); } counter++; } </script> <form action="agenda2.jsp" method="get" onsubmit="show_array(chats)" > <p> <textarea id="chatlet" rows="10" cols="30"></textarea> </p> <input type="submit" value="Send Chat"> </form> </body> </html> A: You need to add return keyword with onsubmit like onsubmit="return show_array(chats)" and then return false in the JS function. Code: <form action="agenda2.jsp" method="get" onsubmit="return show_array(chats)" > JS counter = 0; var chats = []; function show_array(array) { array[counter] = document.getElementById("chatlet").value; for (x = 0; x < array.length; x++) { document.write(array[x] + "<br/>"); } counter++; return false; } DEMO Add tomato and saute till it is completely cooked,and masala starts to leave the sides of the pan. Pour in the coconut milk and add salt to taste.Add the cooked vegetables and cook for 3 to 5 minutes on low flame or until the gravy turns thick.Switch off the stove,add coriander leaves and mix well. In a heavy bottomed pan arrange the vegetable masala and cooked rice in layers.Sprinkle chopped coriander leaves, garam masala( 1/8 tsp) and few drops of ghee(adding ghee is optional) on each layer of rice.Garnish with fried onions,cashew nuts and raisins.Cover the vessel with aluminium foil. Preheat oven to 200 deg C.Bake this for about 10 to 12 minutes.(For stove top method,heat a tava/dosa pan and place the biriyani vessel on top of the tava,reduce flame to low and cook for about 20 minutes.) Serve with onion salad. NOTES If you like more masala for the biriyani,use 1 and 1/4 cup rice ( like in the pic) or use 1.5 cups rice for a milder version.(I usually get about 3.5 cups cooked rice from 1 cup basmati rice.)// Copyright 2020 Google LLC // // Licensed under the Apache License, Version 2.0 (the "License"); // you may not use this file except in compliance with the License. // You may obtain a copy of the License at // // http://www.apache.org/licenses/LICENSE-2.0 // // Unless required by applicable law or agreed to in writing, software // distributed under the License is distributed on an "AS IS" BASIS, // WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. // See the License for the specific language governing permissions and // limitations under the License. syntax = "proto3"; package google.ads.googleads.v3.resources; import "google/ads/googleads/v3/enums/affiliate_location_feed_relationship_type.proto"; import "google/ads/googleads/v3/enums/feed_attribute_type.proto"; import "google/ads/googleads/v3/enums/feed_origin.proto"; import "google/ads/googleads/v3/enums/feed_status.proto"; import "google/api/field_behavior.proto"; import "google/api/resource.proto"; import "google/protobuf/wrappers.proto"; import "google/api/annotations.proto"; option csharp_namespace = "Google.Ads.GoogleAds.V3.Resources"; option go_package = "google.golang.org/genproto/googleapis/ads/googleads/v3/resources;resources"; option java_multiple_files = true; option java_outer_classname = "FeedProto"; option java_package = "com.google.ads.googleads.v3.resources"; option objc_class_prefix = "GAA"; option php_namespace = "Google\\Ads\\GoogleAds\\V3\\Resources"; option ruby_package = "Google::Ads::GoogleAds::V3::Resources"; // Proto file describing the Feed resource. // A feed. message Feed { option (google
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account the tenure of all dwellings in the overall sample. Section Four on the private rented sector contains only three tables, but one, in particular (Table 4.1), that is based on the Family Resources Survey, provides further useful insights into the position of the private rented sector in Northern Ireland, where an estimated 32 per cent of all tenants have been in their current property for five or more years, the highest of all UK regions (a figure that is very close to the 31 per cent emerging from the Housing Executive’s 2016 Private Tenant Survey. The comparable figure for the UK as a whole is 25 per cent, a difference that may reflect a combination of a number of factors, including higher levels of benefit dependency and lower average incomes in Northern Ireland, but may also reflect differences in landlords’ attitudes and security of tenure. Finally, it is also worth highlighting a figure that re-emphasises the close inter-connections between social housing and the private rented sector. Table 3.11 provides statistics on the number of homeless households accepted as Full Duty Applicants over a fourteen year period. In 2017-18, more than 1,500 were accepted on the basis of ‘loss of (private) rented accommodation’, a figure that has been rising on an irregular upward curve in recent years (from 988 in 2011-12) and the first time that it has exceeded 1,500 since 2007-08, the year of the post GFC housing market slump. This blog has highlighted a number of key figures emerging from Housing Statistics 2017-18 that illuminate aspects of the private rented sector in Northern Ireland. It has drawn attention to the particular challenges of providing accurate data on this sector of the market and recommends caution and triangulation where apparently contradictory or unlikely figures emerge. Good quality information on the sector is important – particularly given the ongoing interest in private rented sector related legislation, policy development and evaluation. This indeed will be a particular focus for the second meeting of CaCHE’s Northern Ireland KE Hub in January 2019, when as part of the Hub meeting, CaCHE Director, Professor Ken Gibb, will lead a stakeholder engagement session that will draw on the research undertaken with the Urban Big Data Centre, based at Glasgow University, to help inform the development and evaluation of private rented sector legislation and policy in Northern Ireland. Professor Joe Frey is a Knowledge Exchange Broker for the UK Collaborative Centre for Housing Evidence.A compensatory base change in U1 snRNA suppresses a 5' splice site mutation. Indirect evidence suggests that the 5' end of U1 snRNA recognizes the 5' splice site in mRNA precursors by complementary base pairing. To test this hypothesis, we asked whether point mutations in the alternative 12S and 13S 5' splice sites of the adenovirus E1A gene can be suppressed by compensatory base changes in human U1 snRNA. When the mutant E1A and U1 genes are contransfected into HeLa cells, we observe efficient suppression of one mutation at position +5 in the 12S splice site, but exceedingly weak suppression of another mutation at position +3 in the 13S splice site. These and other results suggest that base pairing between U1 and the 5' splice site is necessary but not sufficient for the splicing of mRNA precursors.Q: How do you use the mapped value? I have a mapping of map <ShapeType, vector <Shape *> > shapeMap; And I insert random shapes into the map. I want to use the method(Draw) for the mapped value. How do you go about doing that, when I traverse through the map? void RandomAttributes(Shape *shape); // declare our objects, and pointers for downcasting MyRect rObj, *rPtr; MyTriangle tObj, *tPtr; MyCircle cObj, *cPtr; void main() { int shapes; // loop index // seed the random number generator srand((unsigned int)time(0)); // allow the user time to move the console window away // from the FilledShapes window are cout << "Move this window to the lower right of the screen, and press ENTER to continue:\n"; cin.get(); // define our array size const int baseSize = 3; // create an vector of base class pointers vector <Shape *> baseShape(baseSize); // initialize our vector of base class pointers //initialize vector of shapes baseShape[0] = &rObj; // a MyRect IS A Shape baseShape[1] = &tObj; // a MyTriangle IS A Shape baseShape[2] = &cObj; // a MyCircle IS A Shape enum ShapeType { MyRectangle = 0, MyTriangle = 1, MyCircle = 2 }; //map map <ShapeType, vector <Shape *> > shapeMap; for (int i = 0; i<PROGRAM_RUN; i++) { // clear the window // note that I can use ANY instance of a MyRect // object to clear the window baseShape[0]->ClearScreen(); int rNum = rand() % 3; //CREATING RANDOM SHAPES // choose random parameters for each rectangle RandomAttributes(baseShape[rNum]); //insert shape shapeMap.insert(pair<ShapeType, vector <Shape *>>(ShapeType(rNum), baseShape)) ; } for (map <ShapeType, vector <Shape *> >::iterator pos = shapeMap.begin(); pos!= shapeMap.end(); ++pos) { //DOES NOT WORK pos->second->Draw(); } } My current implementation: for (map <ShapeType, vector <Shape *> >::iterator pos = shapeMap.begin(); pos!= shapeMap.end(); ++pos) { //DOES NOT WORK pos->second->Draw(); } } How do I traverse through the map and use the draw method as follows: mapped values I want to implement as follows: //baseShape[0]->Draw(); //baseShape[1]->Draw(); //baseShape[2]->Draw(); If my datatype of the map is baseShape vector pointer. A: What you propose doesn't work because pos->second isn't a Shape*, it's a vector<Shape*>. You have to iterate over that second one too: for (map <ShapeType, vector <Shape *> >::iterator pos = shapeMap.begin(); pos!= shapeMap.end(); ++pos) { vector<Shape*>& shapes = pos->second; for (size_t i = 0; i < shapes.size(); ++i) { shapes[i]->Draw(); } } Or if you can use C++11: for (auto& pr : shapeMap) { for (auto shape : pr.second) { shape->Draw(); } } using System.Text.Json.Serialization; namespace Essensoft.AspNetCore.Payment.Alipay.Response { /// <summary> /// AntfortuneEquityInstpointSendResponse. /// </summary> public class AntfortuneEquityInstpointSendResponse : AlipayResponse { /// <summary> /// 积分发放流水，发放结果为true时，流水号可唯一索引本次发放记录 /// </summary> [JsonPropertyName("point_trans_no")] public string PointTransNo { get; set; } /// <summary> /// 积分发放结果，true：成功；false：失败 /// </summary> [JsonPropertyName("send_result")] public bool SendResult { get; set; } } } In a dramatic post that sent social media shockwaves, a student livestreamed his pre-suicide message on Facebook before jumping to his death off the 19th floor of a hotel in Mumbai. Arjun Bhardwaj, a 23-year-old student, was found lifeless on the ground floor of the Hotel Taj Lands End in Bandra at around 6.30pm on Monday, Indian media reported. The police said Bhardwaj left a suicide note, in which he said he was depressed. The dramatic Facebook video had gone viral. Police told the Hindustan Times that Bharadwaj posted about suicide on his Facebook page, and his father visited him in Mumbai four days ago after his friends alerted his father about the posts. Bharadwaj, from Bengaluru, was student at Narsee Monjee Institute of Management Studies. He lived alone in his Andheri flat in Mumbai before his retired father came to spend time with him, said police. The paper quoted police as saying that Bharadwaj could not clear his BCom final year and was allegedly under the influence of alcohol at the time of his death. The report added that Bharadwaj was under pressure to complete his studies and get a job to support their family of four
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an invaluable service to Member States. Noting with interest the proposal for central oversight of the United Nations libraries and development of a virtual library, CARICOM looked forward to the creation of a single multilingual electronic gateway to the library's information and documents. Supporting the reduction in paper use, however, the Community wished to emphasize the need to make limited copies of those documents available in hard copy format. Regarding United Nations information centres, she supported, in principle, the need for rationalization of regional information centres through the creation of regional hubs. At the same time, their establishment should take place on a case-by-case basis, taking into account the unique needs and interests of the regions involved and following consultations with relevant countries. In many cases, the centres remained a vital link between the Organization and the people they served. In particular, she reaffirmed the importance of the information centre in Port-of-Spain. She was also pleased that the DPI was cognizant of the importance of the establishment of an enhanced information component in the United Nations Development Programme (UNDP) Multi-Island Office in Kingston, Jamaica. MARIANA OLIVERA (Mexico) said that in light of the ongoing revolution in information and communication technologies, the large amount of information disseminated by the Organization and the myriad issues it considered, the review of the Organization’s information activities must be undertaken with the utmost responsibility. She agreed on the need for a good definition of the DPI. The definition to be proposed by the Secretariat should include work that went beyond the mere dissemination of information. It should also include the role of the Department as a liaison between the Organization and different parts of civil society, its role in seeking out strategic partnerships and education and training programmes. She said clearly outlined objectives were needed for a broad revision of the Organization’s information activities and that should not be based only on the cost of various activities. Regarding the shared responsibility of the Department and the Committee on Information, she said that communication and information flows between the two should be constant and transparent. The work between those two entities must be promoted. She appreciated the identification and review of the DPI on its key activities, including publications, libraries and information centres. The Committee on Information should consider, evaluate and complete the activities in the field of information, so that the General Assembly could approve decisions in that field. The role of information centres should be improved. She agreed with the decision to reallocate resources to give priority to the information centres in developing countries. The proposal must, however, be examined in greater depth before making any decisions. MOHAMMAD HASSAN FADAIFARD (Iran) said that in the new millennium, information and communication played an important role in national empowerment and sustainable development. The report of the Secretary-General on the question of information was, therefore, a matter of utmost interest. He said Iran fully supported the idea that the capacity of the DPI should be enhanced, a process that required the active participation of Member States. In relation to any new operating model for the DPI in New York and a new concept for the information centres, he said, Iran believed that activities in the areas of special interest to developing countries should be further intensified. Information centres in developing countries should be strengthened; they should continue to evolve their own Web pages in local languages. The proposed United Nations regional information hub in developed nations was a positive initiative. He said Iran supported the enhancing of the United Nations Web site. The balance between electronic and traditional means of communication should be maintained. The proposal to improve and integrate the management of the United Nations libraries was also to be welcomed. SIGNE ROPKE (Denmark), speaking on behalf of the European Union and associated States, reiterated the Union’s commitment to the freedom of expression and information. Independent media was a crucial element in building democracy. Technology reshaped the ways of consuming information and continued to create new challenges for the DPI. The Department’s traditional tasks remained important. The DPI’s core activities must be determined. Policies to strengthen DPI’s effectiveness and efficiency must be formulated in order for it to meet the challenges of the twenty-first century. The United Nations should reach out to the disseminators of information using the latest technologies. The DPI must realize the slogan, “Global Vision, Local Voice”. What seemed technologically impossible a year ago was a truism today, she said. Not all, however, had benefited from developments in information and communication technologies. Billions of people still lacked basic needs, such as water, education and health care. While the Internet could not substitute for poverty eradication programmes, developing and developed nations needed to work together to bridge the divide, so that poor nations were not left behind. In the changing environment of new technologies and opportunities, the United Nations must bring its important message to as many people as possible. Reform was not just reducing costs and improving efficiency. The overall objective should be to enhance the effectiveness of United Nations information activities. It was essential that the United Nations make communications and information strategies an integral part of the strategic management of the Organization, she said. The DPI had an important role in keeping the world fully informed of the aims and activities of the United Nations. The Union remained fully supportive of DPI’s important role. The United Nations could not achieve its purposes if the peoples of the world were not informed of the aims and activities of the United Nations. The importance of the Web site would continue to grow in the future, although further development of the Web site could not be seen separately from DPI’s other activities. The Union, therefore, continued to encourage the DPI to set priorities and apply its resources to ensure that the United Nations message was delivered using the right technology, approaching the correct audiences and with the appropriate mix of communication tools. The United Nations global message should be delivered in a local voice, she said. The Union recognized the efforts to put valuable information on the Web in the six official languages on a range of important themes. A good example was the Web page that told the world what the United Nations was doing to fight terrorism. Enhancing multilingualism as an integral part of the daily work for updating and developing the United Nations Web site was important. The United Nations must ensure a multilingual approach to the availability of public information, within budgetary constraints. Through organizational steps, it was possible to strengthen existing content and improve the multilingual character of the Web site. Mr. AL-ZAYANI (Bahrain) said that freedom of speech was one of the foundations of democracy. His country was convinced of the need to protect individual freedom and equality. The freedom of speech, press, scientific research and publications was all recognized in his county. Every citizen had the right to express his views by any means. Experience had shown that the role of information in development was extremely important, he continued. For information to play its proper part, however, it was necessary to make use of the progress in ICT, which should not be used to increase the digital divide between the developed and developing countries. That was where the United Nations could play an important role through its Department of Public Information. Access to modern technology should be guaranteed to all. Over the years, the idea of creating a new information order, which would be more just and effective and help to create a new understanding among nations, had gradually become accepted, as reflected in several relevant Assembly resolutions. In particular, it had been recognized that it was necessary to eliminate an imbalance in the access to ICT. It was important to improve the capacity of developing countries in the information and communications field, he said. The best way to do that was through cooperation to develop communications infrastructure. In that context, he was grateful to the Secretary-General for having created the United Nations Information Technology Service, the Health Inter Network and Information and Communications Technology Task Force, which could help narrow the gap between developed and developing countries. Among other achievements, he also referred to the question of integrating information aspects in the United Nations Development Programme (UNDP) activities. United Nations information centres had become an important source of culture, making the public more aware of the United Nations activities, he said. Their effectiveness needed to be consolidated, as far as possible. It was also necessary for those centres to target a wider public through new means of access, which would supplement other methods of work. The needs for posters and publications in all areas also needed to be met. The DPI had been successful in a number of its activities, including those related to recent major international conferences. He also hoped special informational programmes would be devised on the issue of Palestine. JON YONG RYONG (Democratic People’s Republic of Korea) said the rapid development of information and communications technology was greatly affecting every aspect of human activities in the political, economic, cultural and other fields. Such technology was directly related to implementing the Millennium Development Goals, which was a high priority of the United Nations. The gap between the developed and the developing countries in the field of public information continued to widen. Narrowing it should be a top objective in international public information activities. Inequality and imbalances persisted in the field of public information and communication; the fact that the means of public information were subjected to the monopoly of certain groups distorted information presented on the realities of the developing countries. All Member States should contribute to ensuring that public information activities promoted understanding and cooperative relations among nations, by establishing an equitable international information and communication order. He said international assistance such as the transfer of advanced technology, training of experts and financial investment for enhancing the capacity of the developing countries should be strengthened. Great attention should be given to enhancing DPI’s capabilities and activities. It was important to ensure objectivity in United Nations public information activities and increase coverage of development issues. He appreciated the Department’s efforts to build the capacity of developing countries
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It’s far from a labor saving approach. With your most important accounts on the line, your campaigns need to be even more personalized, and more customized to really connect with your target audience. So is it worth it? The answer to that depends on the type of business and industry you’re in, but if you’re like me this list will help you take a closer look at the pros and cons of ABM. For more information on ABM, join Pardot on December 13 for ‘Beyond the Hype: Making Account-Based Marketing Work for You,’ featuring guest speaker Lori Wizdo, Vice President and Principal Analyst at Forrester Research. Pro: ABM will up your personalization game. This is a pro in the age of customer-centric marketing, but be careful – ABM doesn’t take personalization lightly. With account based marketing, your campaigns will need to speak to a whole account so it can’t sound mass-produced. This is a delicate job meant to carefully cultivate relationships and brand awareness on a 1:1 level – at scale. Sound like enough of a challenge? Just wait. The approach requires an almost extreme level of focus on the unique pain-points, issues, and market of each of your target accounts. You’ll need to make sure your sales and marketing teams are tightly aligned in order to deliver a truly seamless customer experience. Con: You need to multiply the amount of content you’ll need by the number of accounts you target. Remember how I mentioned that ABM is labor intensive? For each of the accounts you target with this strategy, you’ll need to identify the right messaging, the right cadence, and then create the right content to sustain a campaign. If you have a strong content team with enough resource and the right tool set (hint: marketing automation really, really comes in handy for this part), then it’s doable. Again, a closely aligned marketing and sales team will be essential because how and when your sales team distributes your content will need to be tuned to each of your disparate campaigns. Pro: ABM can help you zero in on important accounts If done correctly, ABM can give your most important accounts some genuine TLC. You’ll get to know them well from a marketing perspective, and you’ll be able to create the kind of campaigns and content that offer real value. It’s not an easy thing to do, but it’s worth it if you have just a few top accounts that make up the bulk of your target audience. Particularly where cultivating relationships with current customers is concerned, this can be a big help in creating customer evangelists and true fans of your brand. Con: An ABM strategy works best with just a few important accounts ABM is not a strategy that you can expand to include every account you have – unless of course, you only have a handful. With the necessary level of detail, it becomes too easily unwieldy and almost impossible to leverage across the hundreds or even thousands of accounts that most businesses will have. In that sense, it’s not a strategy that is meant for every business or every industry. The good news is that the general elements of ABM are the same as the general elements of any other customer-focused marketing strategy: personalization, customization, and a streamlined, buyer-directed buying cycle. These can be much more easily integrated into a marketing strategy that’s a better fit for you business. Pro: You don’t need any special tools for ABM – except two. If you’re planning to implement an Account Based Marketing strategy, there are just two tools you’ll want to have to ease some of the labor intensity and make it easier to manage: marketing automation and data analytics software. Truthfully, you’ll want to have both anyway for any kind of customer-centric marketing, but when it comes to ABM, these tools are a must. A marketing automation platform provides a way to easily create, manage and most importantly – track – campaigns for each of your top accounts. Built in scoring and grading features become paramount because you’ll need to make sure that you’re focusing on the warmest leads at each stage to help your sales team close deals at that scale. You’ll also need to be carefully tracking engagement metrics, and that’s where data analytics software comes in. Engagement becomes much more important when targeting an entire account, and getting regular data on how well your campaigns are performing withe each of your target accounts is the best way to make sure that you’re able to deliver the right information at the right time. ABM – like any other marketing strategy, isn’t going to work for everyone. Creating your own list of pros and cons will help you identify the ways in which ABM may – or may not – fit into your overall marketing strategy. Making sure you’re closely aligned with your sales team and your c-suite will help you set goals for your overall marketing efforts and make sure that as your strategies evolve, you’re able to meet the needs of your clients and prospects. Still not sure if ABM is right for you? Reserve your seat for ‘Beyond the Hype: Making Account-Based Marketing Work for You‘ and hear from guest speaker Lori Wizdo for Forrester Research. ]]>http://www.pardot.com/blog/pros-cons-account-based-marketing/feed/0Using Peer Research and Survey Data to Drive Lead Generationhttp://www.pardot.com/blog/using-peer-research-survey-data-drive-lead-generation/ http://www.pardot.com/blog/using-peer-research-survey-data-drive-lead-generation/#respondMon, 05 Dec 2016 16:00:04 +0000http://www.pardot.com/?p=47546Peer research is a much overlooked resource for B2B marketers, but it’s actually one of the most helpful methods of teasing out buyers pain points. For example, on average, prospects receive over 3 invitations per day to attend webinars, download case studies or read the latest white paper. How do you cut through all that noise? Over 70% of B2B marketers self-report that they don’t have a great answer. How’d we know that? We asked them! That’s the beauty of survey based lead generation. Polling your prospects to learn more about them fuels both immediate lead flow and hyper relevant content. You might have read our last blog, Enabling Continuous Customer Engagement, where we discussed that today’s marketer’s opportunity is to create an ongoing dialogue with their prospects and customers. That’s great, but how do you create content that is engaging and targeted enough to fuel this dialogue? Survey Based Lead Generation Brands like DiscoverOrg leverage Survey Based Lead Generation programs to: Overcome the hardest part of the sales process: making initial contact Open doors and begin the dialogue with their prospects Develop a “needs profile” for their target accounts. Create a foundation for tailoring their pitch and outbound messaging. The results are immediate: Survey respondents are, by definition, qualified leads as they were handpicked to participate and provide the information that you wanted to capture. And what’s even more interesting is that peer based research drives a 36% higher engagement rate vs “traditional” content. Why? Consider your personal interest level in reading a whitepaper or attending a webinar that features insights from people just like you. It’s much harder to resist learning more about your industry, role and related opportunities from fellow business owners who know your difficulties and form a benchmark for your success. And once you’ve created the survey, the resulting data is owned by you. You now have a unique perspective on the industry to share with your prospects and customers. Consider all of the campaign possibilities: social teasers, webinars, infographics, eBooks and in-person thought leadership spots. When it comes to sharing and promoting your content, survey data gives you another edge: industry influencers crave original source content and perspectives to share with their followers, and guess what, your survey data is just what they are looking for. ]]>http://www.pardot.com/blog/using-peer-research-survey-data-drive-lead-generation/feed/03 Reasons Lead Nurturing is for Everyonehttp://www.pardot.com/blog/3-reasons-lead-nurturing-everyone/ http://www.pardot.com/blog/3-reasons-lead-nurturing-everyone/#commentsFri, 02 Dec 2016 19:43:46 +0000http://www.pardot.com/?p=47538Ah, lead nurturing. We meet again. There’s no shortage of good reasons to make it a core part of your marketing strategy: you’ll build better relationships with customers, you’ll have another chance to recapture cold or dead leads, you’ll stay top of mind and ensure that you’re in front of your prospects when they’re getting ready to make a purchasing decision. No matter the unique challenges of your industry, lead nurturing is on B2B marketing strategy that’s universal. Here are three reasons lead nurturing can – and will work for you. If you’re in the life sciences industry – or curious about how to develop a consistent lead nurturing strategy for that industry, join David Chapin, CEO of Forma Life Science Marketing and author of the book: Making the Complex Compelling — Creating High Performance Marketing in the Life Sciences for his webinar presentation ‘The Secrets
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Columbia. Colorado will bring it to 181. They believe that when they hit 270, they will have a pool of votes that will go to whoever wins the popular vote in these states. They will crowd out all the opposition. THE ROAD TO ONE PARTY RULE When our country goes to a popular vote, the road to socialism will be swift and merciless. They need another 12 states and are working on that as we speak. Unfortunately, over the years, Americans have been dumbed down and have no clue what a popular vote will do to this country. If they get to 270, there will be lawsuits, but the fact remains this is dangerous. It was concocted by George Soros’s son, although they will tell you it was three businessmen. THE COMPACT GIVES FEWER PEOPLE THE VOTE The advocates of the NPVC will tell you it is “one man, one vote.” It is the opposite. It gives fewer people the vote. The NPV’s greatest threat (or certainly one of them) is that no one candidate has to amass the 270 electoral votes through compromise with states, with other candidates and with voters. The candidate need only achieve a plurality of votes…I said this before but it comes back to me as outstandingly dangerous. If we have two major candidates and the Dems introduce one or two or three fake candidates, the one that gets as little as 21% of the vote will win the popular vote with a plurality and be, according to the Compact, awarded the electoral votes because he wins the popular votes. It tramples our Constitution and ends the Republic. NPV Will: Federalize the vote Destroy state sovereignty in the Presidential election Circumvent the Constitution Disenfranchise voters by giving as few as 11 states the power to decide the election. It will ignite endless litigation Reduce voting to the lowest common denominator Give a handful of states supremacy MORE INFORMATION ON THE LINK The National Popular Vote – 11 States Can Decide the Presidential Election.size 8000 .text@48 jp lstatint .text@100 jp lbegin .data@143 c0 .text@150 lbegin: ld a, 30 ldff(00), a xor a, a ldff(ff), a inc a ldff(4d), a stop, 00 ldff(4d), a stop, 00 ldff(4d), a stop, 00 ld a, 02 ldff(43), a ld b, 97 call lwaitly_b ld a, 99 ldff(45), a ld a, 40 ldff(41), a ld a, 02 ldff(ff), a xor a, a ldff(0f), a ei .text@1000 lstatint: ld a, 08 ldff(41), a .text@1157 ltest_if: ldff a, (0f) cmp a, e2 jrnz lprint_ly xor a, a ldff(0f), a ld c, 35 lwait_nly: dec c jrnz lwait_nly nop jr ltest_if lprint_ly: ldff a, (44) jp lprint_a .text@7000 lprint_a: push af ld b, 91 call lwaitly_b xor a, a ldff(40), a ld bc, 7a00 ld hl, 8000 ld d, 00 lprint_copytiles: ld a, (bc) inc bc ld(hl++), a dec d jrnz lprint_copytiles pop af ld b, a swap a and a, 0f ld(9800), a ld a, b and a, 0f ld(9801), a ld a, c0 ldff(47), a ld a, 80 ldff(68), a ld a, ff ldff(69), a ldff(69), a ldff(69), a ldff(69), a ldff(69), a ldff(69), a xor a, a ldff(69), a ldff(69), a ldff(43), a ld a, 91 ldff(40), a lprint_limbo: jr lprint_limbo .text@7400 lwaitly_b: ld c, 44 lwaitly_b_loop: ldff a, (c) cmp a, b jrnz lwaitly_b_loop ret .data@7a00 00 00 7f 7f 41 41 41 41 41 41 41 41 41 41 7f 7f 00 00 08 08 08 08 08 08 08 08 08 08 08 08 08 08 00 00 7f 7f 01 01 01 01 7f 7f 40 40 40 40 7f 7f 00 00 7f 7f 01 01 01 01 3f 3f 01 01 01 01 7f 7f 00 00 41 41 41 41 41 41 7f 7f 01 01 01 01 01 01 00 00 7f 7f 40 40 40 40 7e 7e 01 01 01 01 7e 7e 00 00 7f 7f 40 40 40 40 7f 7f 41 41 41 41 7f 7f 00 00 7f 7f 01 01 02 02 04 04 08 08 10 10 10 10 00 00 3e 3e 41 41 41 41 3e 3e 41 41 41 41 3e 3e 00 00 7f 7f 41 41 41 41 7f 7f 01 01 01 01 7f 7f 00 00 08 08 22 22 41 41 7f 7f 41 41 41 41 41 41 00 00 7e 7e 41 41 41 41 7e 7e 41 41 41 41 7e 7e 00 00 3e 3e 41 41 40 40 40 40 40 40 41 41 3e 3e 00 00 7e 7e 41 41 41 41 41 41 41 41 41 41 7e 7e 00 00 7f 7f 40 40 40 40 7f 7f 40 40 40 40 7f 7f 00 00 7f 7f 40 40 40 40 7f 7f 40 40 40 40 40 40 Pages Search This Blog Monday, March 31, 2008 Almost two decades have elapsed since Dr. James Hansen, a scientist with NASA Goddard Space Institute, injected global climate change into the political bloodstream. “It’s time to stop waffling,” Hansen told a Congressional panel. “The greenhouse effect is here.” Yet the United States is no closer to adopting an overarching policy to curb greenhouse gas emissions than it was in the summer of 1988. Much of this inaction can be attributed to the successful disinformation campaign underwritten by fossil energy interests like Exxon Mobil and the Western Fuels Association. Aiding and abetting this campaign was a handful of contrarian scientists who publicly challenged the existence of a scientific consensus on global climate change. Because these so-called “climate skeptics” possessed scientific credentials, reporters and commentators gave them equal time without performing any due diligence to ferret out the political agenda that lurked behind their public statements. Given nearly unlimited access to the media, climate skeptics successfully sowed doubt and confusion in the minds of decision-makers and ordinary citizens about the severity of the problem and the urgency for action. While the climate change denial effort has lost steam in recent years, the disinformation tactics used in that campaign haven’t gone away. Instead, they are being retooled and redeployed to challenge the most visible manifestation of carbon reduction policies: windpower installations. Wind generating capacity is increasing dramatically as more states adopt requirements on utilities to increase their supplies of renewable energy. But not everyone is welcoming this change, and those who don’t want to live near wind turbines are fighting back. In recent years, an Internet-based disinformation campaign has sprung up to both oppose individual wind projects and challenge windpower’s effectiveness in reducing greenhouse gas emissions. An example of this lamentable trend is the Industrial Wind Action Group (www.windaction.org), which serves as a bulletin board for antiwind commentary and articles highlighting grass-roots resistance to specific windpower proposals. Among the myths this web site and others like it propagate is the contention that, contrary to the prevailing wisdom, zero-emission energy sources like wind actually create more carbon dioxide when their impact on the electric grid is taken into account. The argument goes like this: the wind doesn’t blow all the time, therefore utilities have to
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Like Manning, VanDam plays well just about every day – but Sundays seem to be his day to shine brightest. Only two more days will tell whether or not KVD can come from behind to notch his 21st career victory, but one thing’s for sure – his classy character – and willingness to share his game plan with those of us watching from home will always count as a win.Profile Samiullah Shenwari is a legbreak bowler and a right-hand batsman from Afghanistan who made his first-class debut against Zimbabwe XI in August 2009. Shenwari was a part of Afghanistan side that was promoted to Division Two, which allowed them to take part in the ICC World 2009 Qualifiers and gained ODI status. He made his ODI debut against Scotland at Benoni in April 2009. He also played for Afghan Cheetahs team in the Faysal Bank Twenty20 Cup 2011/12. In 2012, Shenwari was included in the T20I squad for the World Twenty20 in Sri Lanka.{-# LANGUAGE CPP #-} {-# LANGUAGE ExplicitForAll #-} {-# LANGUAGE FlexibleContexts #-} {-# LANGUAGE FlexibleInstances #-} {-# LANGUAGE GeneralizedNewtypeDeriving #-} {-# LANGUAGE IncoherentInstances #-} {-# LANGUAGE MultiParamTypeClasses #-} {-# LANGUAGE ViewPatterns #-} {-# LANGUAGE OverloadedStrings #-} {- | Module : Text.Pandoc.Parsing Copyright : Copyright (C) 2006-2020 John MacFarlane License : GNU GPL, version 2 or above Maintainer : John MacFarlane <[email protected]> Stability : alpha Portability : portable A utility library with parsers used in pandoc readers. -} module Text.Pandoc.Parsing ( take1WhileP, takeP, countChar, textStr, anyLine, anyLineNewline, indentWith, manyChar, many1Char, manyTillChar, many1TillChar, many1Till, manyUntil, manyUntilChar, sepBy1', notFollowedBy', oneOfStrings, oneOfStringsCI, spaceChar, nonspaceChar, skipSpaces, blankline, blanklines, gobbleSpaces, gobbleAtMostSpaces, enclosed, stringAnyCase, parseFromString, parseFromString', lineClump, charsInBalanced, romanNumeral, emailAddress, uri, mathInline, mathDisplay, withHorizDisplacement, withRaw, escaped, characterReference, upperRoman, lowerRoman, decimal, lowerAlpha, upperAlpha, anyOrderedListMarker, orderedListMarker, charRef, lineBlockLines, tableWith, widthsFromIndices, gridTableWith, gridTableWith', readWith, readWithM, testStringWith, guardEnabled, guardDisabled, updateLastStrPos, notAfterString, logMessage, reportLogMessages, ParserState (..), HasReaderOptions (..), HasIdentifierList (..), HasMacros (..), HasLogMessages (..), HasLastStrPosition (..), HasIncludeFiles (..), defaultParserState, HeaderType (..), ParserContext (..), QuoteContext (..), HasQuoteContext (..), NoteTable, NoteTable', KeyTable, SubstTable, Key (..), toKey, registerHeader, smartPunctuation, singleQuoteStart, singleQuoteEnd, doubleQuoteStart, doubleQuoteEnd, ellipses, apostrophe, dash, nested, citeKey, Parser, ParserT, F, Future(..), runF, askF, asksF, returnF, trimInlinesF, token, (<+?>), extractIdClass, insertIncludedFile, insertIncludedFileF, -- * Re-exports from Text.Parsec Stream, runParser, runParserT, parse, tokenPrim, anyToken, getInput, setInput, unexpected, char, letter, digit, alphaNum, skipMany, skipMany1, spaces, space, anyChar, satisfy, newline, string, count, eof, noneOf, oneOf, lookAhead, notFollowedBy, many, many1, manyTill, (<|>), (<?>), choice, try, sepBy, sepBy1, sepEndBy, sepEndBy1, endBy, endBy1, option, optional, optionMaybe, getState, setState, updateState, SourcePos, getPosition, setPosition, sourceColumn, sourceLine, setSourceColumn, setSourceLine, incSourceColumn, newPos, Line, Column ) where import Control.Monad.Identity import Control.Monad.Reader import Data.Char (chr, isAlphaNum, isAscii, isAsciiUpper, isPunctuation, isSpace, ord, toLower, toUpper) import Data.Default import Data.Functor (($>)) import Data.List (intercalate, transpose) import qualified Data.Map as M import Data.Maybe (mapMaybe, fromMaybe) import qualified Data.Set as Set import Data.String import Data.Text (Text) import qualified Data.Text as T import Text.HTML.TagSoup.Entity (lookupEntity) import Text.Pandoc.Asciify (toAsciiChar) import Text.Pandoc.Builder (Blocks, HasMeta (..), Inlines, trimInlines) import qualified Text.Pandoc.Builder as B import Text.Pandoc.Class.PandocMonad (PandocMonad, readFileFromDirs, report) import Text.Pandoc.Definition import Text.Pandoc.Logging import Text.Pandoc.Options import Text.Pandoc.Readers.LaTeX.Types (Macro) import Text.Pandoc.Shared import qualified Text.Pandoc.UTF8 as UTF8 (putStrLn) import Text.Pandoc.XML (fromEntities) import Text.Parsec hiding (token) import Text.Parsec.Pos (initialPos, newPos, updatePosString) import Control.Monad.Except import Text.Pandoc.Error type Parser t s = Parsec t s type ParserT = ParsecT -- | Reader monad wrapping the parser state. This is used to possibly delay -- evaluation until all relevant information has been parsed and made available -- in the parser state. newtype Future s a = Future { runDelayed :: Reader s a } deriving (Monad, Applicative, Functor) type F = Future ParserState runF :: Future s a -> s -> a runF = runReader. runDelayed askF :: Future s s askF = Future ask asksF :: (s ->
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一个循环里使用 partials 来输出相同的内容片段多次，这时你就可以把大块的重复的内容或复杂的显示逻辑放到一个地方。然而这对性能有影响，因为partial助手需要在每个迭代里调用一次。 </para> <para> <code>PartialLoop</code> 视图助手解决了这个问题。 它允许你把迭代条目（实现<code>Iterator</code>的数组或对象）当做模型来传递。它这些把这些条目当作模型迭代、传递给 partial 脚本。在迭代器里的条目可以是 <code>Partial</code> 视图助手允许的任何模型。 </para> <para> 让我们看一下下面的 partial 视图脚本： </para> <programlisting role="php"><![CDATA[ <? // partialLoop.phtml?> <dt><?= $this->key?></dt> <dd><?= $this->value?></dd> ]]></programlisting> <para> 添加下列 "model"： </para> <programlisting role="php"><![CDATA[<?php $model = array( array('key' => 'Mammal', 'value' => 'Camel'), array('key' => 'Bird', 'value' => 'Penguin'), array('key' => 'Reptile', 'value' => 'Asp'), array('key' => 'Fish', 'value' => 'Flounder'), ); ?>]]></programlisting> <para> 在视图脚本中，你可以这样调用 <code>PartialLoop</code> 助手： </para> <programlisting role="php"><![CDATA[ <dl> <?= $this->partialLoop('partialLoop.phtml', $model)?> </dl> ]]></programlisting> <programlisting role="html"><![CDATA[ <dl></dl> <dt>Mammal</dt> <dd>Camel</dd> <dt>Bird</dt> <dd>Penguin</dd> <dt>Reptile</dt> <dd>Asp</dd> <dt>Fish</dt> <dd>Flounder</dd> </dl> ]]></programlisting> </example> <example id="zend.view.helpers.initial.partial.modules"> <title> 在其它模块中解析 Partials </title> <para> 有时候 partial 存在于不同的模块(Module)。如果你知道模块的名称，你可以把它当作第二个参数传递给 <code>partial()</code> 或者 <code>partialLoop()</code>，把 <code>$model</code> 作为第三个参数。 </para> <para> 例如，如果一个你想用一个在 'list' 模块的 pager partial，就象下面这样来运用： </para> <programlisting role="php"><![CDATA[ <?= $this->partial('pager.phtml', 'list', $pagerData)?> ]]></programlisting> <para> 这样，你可以重用原来是特别供给其它模块使用的 partials 。所以，在共享的视图脚本路径里放置可重用的 partials 很可能是个好习惯。 </para> </example> </sect3> <!-- vim:se ts=4 sw=4 et: --> Segregation distortion in Arabidopsis C24/Col-0 and Col-0/C24 recombinant inbred line populations is due to reduced fertility caused by epistatic interaction of two loci. A new large set of reciprocal recombinant inbred lines (RILs) was created between the Arabidopsis accessions Col-0 and C24 for quantitative trait mapping approaches, consisting of 209 Col-0 x C24 and 214 C24 x Col-0 F(7 )RI lines. Genotyping was performed using 110 evenly distributed framework single nucleotide polymorphism markers, yielding a genetic map of 425.70 cM, with an average interval of 3.87 cM. Segregation distortion (SD) was observed in several genomic regions during the construction of the genetic map. Linkage disequilibrium analysis revealed an association between a distorted region at the bottom of chromosome V and a non-distorted region on chromosome IV. A detailed analysis of the RILs for these two regions showed that an SD occurred when homozygous Col-0 alleles on chromosome IV coincided with homozygous C24 alleles at the bottom of chromosome V. Using nearly isogenic lines segregating for the distorted region we confirmed that this genotypic composition leads to reduced fertility and fitness. THE THIRTEENTH COURT OF APPEALS 13-15-00228-CR Manuel Fuentes v. The State of Texas On appeal from the 24th District Court of Calhoun County, Texas Trial Cause No. 2014-06-7434 JUDGMENT THE THIRTEENTH COURT OF APPEALS, having considered this cause on appeal, concludes that the judgment of the trial court should be AFFIRMED. The Court orders the judgment of the trial court AFFIRMED. We further order this decision certified below for observance. October 13, 2016. 1. Technical Field The present invention relates generally to the field of computer systems and, more specifically to a system, method, and computer program product for executing a reliable warm reboot of a partition that includes multiple processors in logically partitioned systems. 2. Description of Related Art A logical partitioning option (LPAR) within a data processing system (platform) allows multiple copies of a single operating system (OS) or multiple heterogeneous operating systems to be simultaneously run on a single data processing system hardware platform. A partition, within which an operating system image runs, may be assigned a non-overlapping subset of the platform's hardware resources. In some implementations, a percentage of system resources is assigned such that system resources are essentially time-sliced across partitions. These platform allocable resources include one or more architecturally distinct processors with their interrupt management area, regions of system memory, and input/output (I/O) adapter bus slots. The partition's resources are represented by its own resources list typically created and maintained by the systems underlying firmware and available to the OS image. Each distinct OS or image of an OS running within the platform is protected from each other such that software errors on one logical partition can not affect the correct operation of any of the other partitions. At a given time, this is provided by allocating a disjoint set of platform resources to be directly managed by each OS image and by providing mechanisms for ensuring that the various images can not control any resources that have not been allocated to it. Furthermore, software errors in the control of an operating system's allocated resources are prevented from affecting the resources of any other image. Thus at a given time, each image of the OS, or each different OS, directly controls a distinct set of allocable resources within the platform. The ability to reboot one of multiple partitions in a logically partitioned system is an important requirement in such a system. This requirement stems from the fact that partitions are supposed to act and behave like independent systems. An independent computer system may be restarted using either a cold reboot or a warm reboot. A cold reboot is defined as restarting the computer system by cycling the power to the computer system off and then back on. When a cold reboot is executed, the various hardware components in the system are reset to a particular, defined state. When a processor is reset, the processor loses all history of what it had been doing prior to being reset. It does not continue to transmit I/O requests, and does not anticipate the receipt of any particular I/O response. When an I/O adapter is reset, it also does not continue to transmit I/O responses, and does not anticipate the receipt of any particular I/O request. A warm reboot is defined as restarting the computer system without cycling the power off and then back on. In a cold boot, system components are tested prior to initialization to ensure that the hardware is functioning properly before control can be passed to the OS. In a warm boot scenario, since the system is assumed to be operating prior to the reboot request, testing of certain system components can be skipped thereby speeding up the boot. Obviously in an LPAR environment, a cold boot is not an option since it impacts not only the partition being rebooted but all other partitions
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the only way to get comfortable while locked up in this dumb stockade—a squat little wood and iron structure, just a bit higher than head level with both my forelegs and my neck locked in it. Not-me had been smart and confiscated my power armor first. Problem was, being locked in this thing left my rear half in a position that nearly begged for sexual assault. I didn’t have the comfort of my power armor anymore, so it was just a matter of mister peripheral vision and kicksies to keep me safe. And of course there was Violet, who was still making deflating noises at me—I was just going to pretend she didn’t exist—but I wasn’t really sure how much help she’d be anyway. She had simply teleported out of her chains when nopony was paying attention. Thankfully, Violet had casually stolen back my gear and was currently carting around my stuff. If I needed somepony to tell me I wasn’t being smart, I had Gale for that. Then again, Violet wasn’t the one in a stockade. On a technicality, Gale wasn’t either. “Frosty, I’m seriously considering leaving you here so that you’ll learn from your mistakes. On the other hoof, both of us know otherwise.” “So that means you’ll save me?” I hopefully asked. Violet faltered, then decided to pat my head. “Sure, let’s pretend that’s what I meant.” she flashed me a wry grin. On the topic of rescue, I remembered that Riverbed was still wandering around somewhere. “No, but seriously. Can you go grab Riverbed? I have no idea what me is up to, and if the Enclave rescue team comes for me and not me, I’m going to be very inconvenienced and they’ll be really bucking surprised when it happens and stuff. So will I, but that’s her problem.” “Any more ‘and’s’, or are you done?” I tapped my chin. Rather, I tried to tap my chin and got annoyed that I couldn’t. “I think that’s really it. Can you find out where the other Frosty went? Assuming all goes well, Riverbed and I’ll figure out how to get out of here before I find out about it.” As I pondered, I realized that I could talk my way out of anything since “Frosty”—and by extension, I—seemed to be in command here. “Okay. I’ll go see exactly what your doppelganger is made of—quite literally, mind you—and the explosions and screaming will tell me where you are later,” Violet agreed. “And now just one last thing to check.” I was about to ask what she meant when everything suddenly went dark and slightly hay-scented. “What’s going on? Where did the light go?” Instinct began to take over and I felt my eyes begin to droop. “It’s really dark and—” I widely yawned. “I guess I’ll take a nap. No time like… the present.” “I… wasn’t expecting that to work.” There was a pat on my head. “Um. Good birdie. Now think about what you’ve done.” X~~~X “Guuuuuuy, where are we going?” I whined. “We’re going to talk to the Cargo Master so that you and your friends have a place to stay,” the shaved bear leading me through town grumbled. At some point in our narcolepsy-fueled adventure, Frosty must have had grown a pair of gigantic balls to have yelled at this pony earlier. The guy was huge! And all he wanted to do was apparently love me, care for me, and cherish me. Wishful thinking perhaps, but it made me giggle on the inside. “Eh… you can prob’ly find your own way, though,” the pony continued. “I still have to, euh, make sure boss lady isn’t gonna flog somepony.” And with that, Cuddle Monster pranced away without even giving me a proper hug goodbye. Rude. As I took collection of my surroundings, I also realized the guy was completely wrong—I had no idea who I was looking for or where I was supposed to be going. The last time I’d been here was ages ago. Whoever this new group was had renovated the heck out of Value Town. King was nowhere to be found and neither was Value Belcher’s Value Flophouse for the economically impaired. That also meant that they’d probably kicked out Doctor Balanced as well, which would be unfortunate. The dingy little run-down buildings had somehow gotten even worse off between the exchange of ownership as well. So I did what I did best—wander about until I got bored. I’d eventually stumble across whoever Cargo Master was, so a bit of sightseeing was probably fine. We weren’t in a rush anyway. Still, finding somewhere for us to temporarily crash was still priority. If I got it done quickly enough, I wishfully hoped of spending the evening gently rubbing the birdie’s tummy. Of course Frosty didn’t like it, but she’d learn. Everypony did at some point. Except Violet, because apparently somepony had rubbed all the fun right out of her. Back on topic, I still found it a bit odd that the ponies here were so… diverse. Wastelanders, raiders, scribes—literally anypony from any faction in the Wasteland was represented around here, sans birdies. I wasn’t going to be one to judge, but it did strike me as odd. But hey, I wasn’t going to complain about the wide array of eye candy. Speaking of eye candy, a neat and orderly line of ponies were making their way past, so I paused on ogling bystanders in favor of the party train slowly scooting past. I politely took a step back to observe. Besides the weird fact that they all wore similarly patterned scarves accompanying their mismatched outfits, they were also chanting “Chugga, chugga, chugga” with every shuffled step. Weeeeeird. Once the creep train had passed through and everypony went back to their business, I returned to my intent observing. Like that one—he had a raideresque sort of rugged charm about him. He also had an adorably dark and potentially edgy color scheme to swoon over—dark red on pink. Earth ponies always looked good in dark colors, especially in red. Whatever wasn’t red was marked up with black and dark gray war paint. His mane was styled the only way raiders knew how—spikes and pointy shapes. On a whim, I mentally named him Studmuffins and began to search the meager crowds for a suitable mate for him. A cursory examination of the crowd would help me locate a suitable match. In an instant, I found her. There was something about the little pink unicorn mare that I immediately tagged as “waifu material”. Her white mane was tied up in a professional little bun, perfect for the Wasteland mechanic on-the-go. The brownish-red smock and barding combination she was wearing was just a size too big on her on her, but it even complimented her unknowing fiancé. The two of them would make an adorable couple. That, and I was somewhat interested what the combination of lightish red and dark red coats would result in. They’d have pretty-lookin’ foals regardless. My fantasies of aesthetics and complimentary colors were politely placed aside so that Violet the fun-killer could have my full attention. “You need to go save Frosty,” she flatly told me with her usual bored look. A small cloud of Frosty’s stuff was lazily orbiting her butt, which was hella distracting. And take time out of non-consensual matchmaking? “Why me, guy?” Heck, the word "sensual" even pops up somewhere in there! How was I expected to work if my little pegapet kept getting herself into trouble all the time? What she needed was a birdcage and a cuttlebone to gnaw on to keep her out of trouble. Once again, Violet sighed. “Because you have guns and I’m busy with deciphering the many oddities of Frosty Winds, Frosty Winds, and her nonsensical ramblings.” I cocked my head at her and pointed out, “You repe—” My voice stopped making noise, so I defaulted to energetically pretending to scream bloody murder. Magic was a load of cheaty nonsense that I had no control over. The sparkles coming off of Violet’s horn stopped once I stopped trying to keep talking. “It will make sense once you see it. Our Frosty is tied up in the stocks. Get her out while I do a bit of my own research.” She unceremoniously dumped the pile of Frosty-loot in front of me and trotted away in search of more fun to consume. Fun for the fun god. Streamers for the throne. Somehow I managed to sling Frosty’s deceptively heavy saddlebag plus armor onto my
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order to have a good determination of the valence quarks and of the sea asymmetry, we also need to include other structure functions, measured in the large-$x$ region. In this global fit, we thus include the following quantities: - The proton structure function $F_2^p$ [@Abt:1993cb; @Ahmed:1995fd; @Aid:1996au; @Adloff:1997mf; @Adloff:1999ah; @Adloff:2000qj; @Adloff:2000qk; @Derrick:1993ft; @Derrick:1994sz; @Derrick:1995ef; @Derrick:1996hn; @Breitweg:1997hz; @Breitweg:1998dz; @Breitweg:1999ad; @Chekanov:2001qu; @Benvenuti:1989rh; @Adams:1996gu; @Arneodo:1996qe; @Whitlow:1991uw]: this is by far the most important type of experimental data. Moreover, it is nearly the only one to contribute to the fit in the small-$x$ or in the high-$Q^2$ region. - The deuteron structure function $F_2^d$ [@Adams:1996gu; @Arneodo:1996qe; @Whitlow:1991uw; @Benvenuti:1989gs]: as we shall see, these data allow the determination of the sea asymmetry. Many points are available in the large- and middle-$x$ regions, where the sea asymmetry is expected to be large. - The neutrino structure functions $F_2^{\nu N}$ and $F_3^{\nu N}$ [@Oltman:pq; @Seligman:mc; @Fleming:2000bg]: these data, in which most of the points are at large values of $x$, are important to fix the strange quark and the valence quark distributions. Note that the data considered here are averaged over neutrinos and anti-neutrinos. - The $F_2^n/F_2^p$ measurements [@Amaudruz:1991nw]: these data constrain the valence quark distributions and the sea asymmetry. Once we know which experiments are fitted, we must find which quantities need to be evolved. Since the $Q^2$ range under consideration in global fits extends up to 30000 GeV$^2$, we need to consider 5 quark flavours: $u$, $d$, $s$, $c$ and $b$. In order to use DGLAP evolution, it is easier to perform linear combinations of the quark distributions. In our case, we shall use 6 flavour-non-singlet distributions $$\begin{aligned} \label{eq:nsdists} xu_V & = & x(u - \bar{u}),\nonumber\\ xd_V & = & x(d - \bar{d}),\nonumber\\ T_3 & = & x(u^+ - d^+),\nonumber\\[-3mm] & & \\[-3mm] T_8 & = & x(u^+ + d^+ - 2 s^+),\nonumber\\ T_{15} & = & x(u^+ + d^+ + s^+ - 3 c^+),\nonumber\\ T_{24} & = & x(u^+ + d^+ + s^+ + c^+ - 4b^+),\nonumber\end{aligned}$$ where $q^+ = q+\bar{q}$. Note that since the proton does not contain constituent strange, charm or bottom valence quarks, we have $s=\bar{s}$, $c=\bar{c}$ and $b=\bar{b}$. At leading order, the $Q^2$ evolution of each of these distributions is given by the DGLAP equation with the splitting $xP_{qq}(x)$. In addition to the non-singlet distributions, we have the singlet quark distribution $$\Sigma = x(u^+ + d^+ + s^+ + c^+ + b^+)$$ which evolves coupled to the gluon distribution $G=xg$, with the full splitting matrix $$\begin{pmatrix} xP_{qq}(x) & 2n_fxP_{qg}(x)\\ xP_{gq}(x) & xP_{gg}(x) \end{pmatrix}.$$ We shall assume that for $Q^2\le 4m_q^2$, the quark $q$ does not enter into the evolution equations. If we invert the relations and express the quark densities $q^+$ in terms of the evolved quantities, we obtain $$\begin{aligned} xu^+ & = & \frac{1}{60}(12\Sigma + 3T_{24} + 5T_{15} + 10T_8 + 30T_3),\\ xd^+ & = & \frac{1}{60}(12\Sigma + 3T_{24} + 5T_{15} + 10T_8 - 30T_3),\\ xs^+ & = & \frac{1}{60}(12\Sigma + 3T_{24} + 5T_{15} - 20T_8),\\ xc^+ & = & \frac{1}{20}( 4\Sigma + T_{24} - 5T_{15}),\\ xb^+ & = & \frac{1}{ 5}( \Sigma - T_{24}).\end{aligned}$$ Now, we can of course write the structure functions considered here in terms of the parton distributions or in terms of the flavour-singlet and flavour-non-singlet distributions[^2]. If, for the sake of clarity, we include other quantities like the neutron structure function, this gives $$\begin{aligned} F_2^p & = & \frac{4x}{9}(u^++c^+)+\frac{x}{9}(d^++s^++b^+) \\ & = & \frac{1}{90}(22\Sigma+3T_{24}-5T_{15}+5T_8+15T_3),\\ F_2^n & = & \frac{4x}{9}(d^++c^+)+\frac{x}{9}(u^++s^++b^+) \\ & = & \frac{1}{90}(22\Sigma+3T_{24}-5T_{15}+5T_8-15T_3),\\ F_2^d & = & \frac{F_2^p+F_2^n}{2}\\ & = & \frac{5x}{18}(u^++d^+)+\frac{4x}{9}c^++\frac{x}{9}(s^++b^+)\\ & = & \frac{1}{90}(22\Sigma+3T_{24}-5T_{15}+5T_8),\\\end{aligned}$$ and for the neutrino structure functions $$\begin{aligned} F_2^{\nu p} & = & 2x(d+s+b+\bar{u}+\bar{c}),\\ F_2^{\nu n} & = & 2x(u+s+b+\bar{d}+\bar{c}),\\ F_2^{\bar{\nu} p} & = & 2x(u+c+\bar{d}+\bar{s}+\bar{b}),\\ F_2^{\bar{\nu} n} & = & 2x(d+c+\bar{u}+\bar{s}+\bar{b}),\\ xF_3^{\nu p} & = & 2x(d+s+b-\bar{u}-\bar{c}),\\ xF_3^{\nu n} & = & 2x(u+s+b-\bar{d}-\bar{c}),\\ xF_3^{\bar{\nu} p} & = & 2x(u+c-\bar{d}-\bar{s}-\bar{b}),\\ xF_3^{\bar{\nu} n} & = & 2x(d+c-\bar{u}-\bar{s}-\bar{b}),\\\end{aligned}$$ If we average over proton and neutron targets, we obtain the neutrino-nucleon structure functions[^3] $$\begin{aligned} F_2^{\nu N} = F_2^{\bar{\nu} N} & = & x(u^++d^++s^++c^++b^+),\\ xF_3^{\nu N} & = & x(u_V+d_V+s^+-c^++b^+),\\ xF_3^{\bar{\nu} N} & = & x(u_V+d_V-s^++c^+-b^+).\\\end{aligned}$$ We may finally average over neutrinos and anti-neutrinos, which leads to $$\begin{aligned} F_2^{\stackrel{(-)}\nu N} & = & x(u^++d^++s^++c^+),\\ & = & \Sigma,\\ xF_3^{\stackrel{(-)}\nu N} & = & x(u_V+d_V).\end{aligned}$$ Initial parametrisation ======================= If we want to perform a DGLAP evolution, we need to fix the parton distribution functions at an initial scale $Q_0^2$. Following the same ideas as in [@Soyez:2002nm], we shall parametrise each quark distribution as the sum of a triple-pole pomeron term and an $a_2/f$-reggeon term. In addition,
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253, 6661, 273, 253, 26518, 273, 253, 8351, 476, 320, 4942, 21010, 15, 187, 688, 1635, 13, 347, 253, 6322, 3082, 275, 247, 1066, 4492, 941, 5048, 13, 627, 403, 15783, 6322, 285, 5939, 6322, 15, 187, 688, 15783, 6322, 13, 347, 2011, 275, 7705, 15, 337, 34, 13, 247, 4294, 2972, 310, 18564, 347, 247, 3943, 281, 1016, 2608, 15, 1198, 1650, 13, 275, 15783, 6322, 13, 253, 4294, 8336, 1907, 1175, 4294, 13687, 33088, 403, 18564, 15, 21910, 13, 15783, 6322, 778, 320, 8069, 908, 672, 253, 1979, 273, 253, 6322, 941, 310, 1781, 285, 253, 4294, 27387, 1055, 310, 2424, 281, 320, 8655, 15, 380, 4294, 2972, 778, 320, 1925, 247, 7741, 2972, 15, 187, 688, 5939, 6322, 13, 347, 2011, 275, 7705, 15, 337, 35, 13, 941, 403, 5195, 313, 45618, 10, 2439, 253, 2862, 2130, 16992, 1293, 5886, 281, 253, 4294, 8336, 285, 12573, 15, 1198, 1650, 13, 5939, 6322, 310, 3839, 908, 672, 253, 4294, 27387, 778, 417, 320, 2684, 1955, 281, 3809, 4866, 285, 672, 253, 1979, 273, 253, 6322, 941, 310, 1355, 824, 347, 253, 1083, 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suggest that their league campaign could yet be one to celebrate.import anvil.server import anvil.tables as tables import anvil.tables.query as q from anvil.tables import app_tables # This is a server module. It runs on the server, rather than in the user's browser. # # To allow anvil.server.call() to call functions here, we mark # them with @anvil.server.callable. @anvil.server.callable def add_tasks(): app_tables.tasks.add_row(name="Buy the shopping", complete=False) app_tables.tasks.add_row(name="Walk the dog", complete=False) @anvil.server.callable def get_tasks(): return app_tables.tasks.search() @anvil.server.callable def add_task(name): app_tables.tasks.add_row(name=name, complete=False) @anvil.server.callable def update_task(task, complete): if app_tables.tasks.has_row(task): task.update(complete=complete) @anvil.server.callable def delete_task(task): if app_tables.tasks.has_row(task): task.delete()As a communication system succeeding the W-CDMA and the HSDPA, an LTE (Long Term Evolution) system is being worked on by the 3GPP (3rd Generation Partnership Project), which is the standardization group for the W-CDMA. In the LTE system, an OFDMA (Orthogonal Frequency Division Multiple Access) system is being considered for the downlink, and an SC-FDMA (Single-Carrier Frequency Division Multiple Access) system is being considered for the uplink. In the OFDMA system, a frequency bandwidth is divided into plural narrower frequency bandwidths (subcarriers), and data are transmitted by being carried on the frequency bandwidths. By contiguously arranging the subcarriers without interfering with each other though the subcarriers may be partially overlapped, it becomes possible to achieve fast transmission and improve the use efficiency of the frequency bandwidths. The SC-FDMA system is a transmission system in which a frequency bandwidth is divided so that plural terminals can transmit using a different frequency bandwidth among the plural terminals to reduce the interference between the terminals. The SC-FDMA system has the characteristics that the variation of the transmitting power becomes small. Therefore, the configuration of the transmitter of the terminal can be relatively simplified. In addition, as the transmission methods in a downlink data channel, there are localized transmission and distributed transmission. In localized transmission, as shown in FIG. 1A, a frequency block is allocated as a unit to each user. For example, in localized transmission, the frequency blocks having good frequency selective fading are allocated. Generally, localized transmission may be effectively used when the size of the transmission data is large and the frequency scheduling effect is required to be enhanced. The frequency block may be called a resource block. In distributed transmission, as shown in FIG. 1B, data are spread (distributed) across the entire available bandwidth without relation to the frequency blocks and transmitted. For example, distributed transmission is generally used when the frequency scheduling may not be performed due to fast movement and when the size of the transmission data is small such as the case of VoIP. In the LTE system, it is required for a single system to support various sizes of packets ranging from packets having a larger size used in browsing a Web site or the like to packets having a smaller size used in VoIP or the like in communications with slow users and fast moving users as well. To support both the localized transmission and distributed transmission by a single system, there has been proposed a communication device in which, when distributed transmission is performed at the resource block level, one resource block is divided into plural divided blocks, and the divided blocks are allocated as the resource blocks. This communication device generates control information with respect to a mobile station to which the resource blocks are allocated. For example, the allocated bandwidth is divided into plural parts and identification codes such as identification numbers indicating the physical locations of the thus-divided and generated plural resource blocks are assigned to the plural resource blocks. In this case, a division number of the resource blocks to be used for distributed transmission among the plural resource blocks is set equal to an allocation unit of the divided resource blocks to be allocated to a mobile station as a unit and is defined as “ND” (where ND is an integer number greater than 0). Namely, the divided resource blocks are assigned by regarding the resource block as a unit. FIG. 2A shows a case where ND=2. According to FIG. 2A, in a case of ND=2, each of the resource blocks used for distributed transmission is divided into two parts (divided resource blocks), and the two divided resource blocks, namely a pair of the divided resource blocks, becomes a unit to be allocated to a mobile station. In this case, the physical locations of the resource blocks used for distributed transmission are predetermined in accordance with the total number of resource blocks used for distributed transmission. In this case, as shown in FIG. 2B, a specific signaling format for transmitting the allocation information includes each field for an ID (UE-ID) of an allocated mobile station, a transmission type indicating which of localized transmission or distributed transmission is to be performed, and allocation information with respect to each resource block, namely, the resource block used for localized transmission and the resource block for distributed transmission. In the fields for the allocation information with respect to the resource blocks, subfields corresponding to the resource blocks are provided, and information of allocated or non-allocated is assigned to the subfields. An assigning method of the allocation information with respect to the resource blocks is called “bitmap”. A base station transmits control bits including such allocation information as many numbers as the number of mobile stations allocated to perform localized transmission and distributed transmission. Non Patent Document 1: R2-062036, “Evolved Universal Radio Access (E-UTRA) and Evolved Universal Terrestrial Radio Access Network (E-UTRAN); Overall description; Stage 2,” Section 16 RF aspectsNatural cryoprotectants combinations of l-proline and trehalose for red blood cells cryopreservation. Cryopreservation of red blood cells (RBCs) holds great potential benefits for supplying transfusion timely in emergencies. Currently, glycerol is the main cryoprotectant permitted in clinical therapy for RBCs cryopreservation, but its broad application is limited by the toxicity and complex deglycerolization process. Successful cryopreservation of RBCs using more effective materials should be studied to reduce freezing damage, increase biocompatibility, and save processing time. Herein, a simple protocol using natural cryoprotectants combinations of l-proline and trehalose attains a low degree of hemolysis (11.2 ± 2.73%) after thawing compared to glycerol. Furthermore, the morphology of RBCs and the activities of Na+/K+-ATPase and Ca2+/Mg2+-ATPase maintain well. Further mechanism study shows that l-proline plays an important role in decreasing the freezing points and inhibiting the growth of ice crystal by permeating into cells during the freezing process. While trehalose works as an inhibitor of ice growth in the freezing process and ice recrystallization in the thawing process. This simple l-proline & trehalose combinations protocol is a promising method to replace current time-consuming and labor-intensive cryopreservation methods of RBCs."D'SOUZA:" "And action." "[PIANO PLAYS]" "When times are tough, you can forget your worries, forget your woes." "Why?" "Because you can always count on... the Democratic Party." "Hit it, boys!" "# Crappy days are here again" "# The skies above are gray again" "# Let us sing a song of cheer again" "# Crappy days are here again" "# All together, shout it now" "# There's no one who will buy it now" "# So let's tell the world about it now" "# Crappy days are here again" "# Your cares will never be gone" "# 'Cause the Dems are here from now on" "# Crappy days are here again" "# The skies above are gray again" "# Let us sing a song of cheer again" "# Crappy days are here again..." "Shh." "[SIREN WAILS]" "[GUNSHOTS]" "# Crappy days are here again" "# The skies above are gray again" "# Let us sing a song of cheer again" "# Crappy days are here again" "# All together, shout it now" " There's no one who will buy it now" " Change has come to America." "# So let's tell the world about it now" "# Crappy days are here again" "# Crappy days are here again" "# Crappy days" "# Are... here" " Agai-ai-n - [CROWD CHANTING "HILLARY"]" "MAN:" "Turn to your left." "D'SOUZA:" "It all began when the Obama administration tried to shut me up." "The United States vs. Dinesh D'Souza." "Please be seated." "Mr. D'Souza has willfully and knowingly violated campaign finance laws." "He gave money to a friend to help her with her campaign." "He did not tell her about it." "Someone who wants to corrupt a candidate wants them to know." "If it were not Mr. D'
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ultan voiced some discontent. The guilt of many shoppers was assuaged. The most committed shopaholic gauged, "I'd really have to spend a lot more dough To be a spendthrift like the sultan's bro." PD-1277-14 COURT OF CRIMINAL APPEALS AUSTIN, TEXAS Transmitted 2/12/2015 5:53:18 PM Accepted 2/13/2015 8:25:01 AM February 13, 2015 ABEL ACOSTA NO. PD-1277-14 CLERK IN THE COURT OF CRIMINAL APPEALS OF TEXAS EX PARTE: JUAN CARLOS REYES THE STATE’S BRIEF ON APPELLEE’S PETITION FOR DISCRETIONARY REVIEW FROM THE COURT OF APPEALS, EIGHTH DISTRICT OF TEXAS CAUSE NUMBER 08-12-00261-CR, TRIAL COURT CAUSE NUMBER 20050C17647-CC7-1, COUNTY COURT AT LAW NO. SEVEN OF EL PASO COUNTY, TEXAS JAIME ESPARZA DISTRICT ATTORNEY 34th JUDICIAL DISTRICT LILY STROUD ASST. DISTRICT ATTORNEY DISTRICT ATTORNEY’S OFFICE 203 EL PASO COUNTY COURTHOUSE 500 E. SAN ANTONIO EL PASO, TEXAS 79901 (915) 546-2059 ext. 3769 FAX (915) 533-5520 EMAIL [email protected] SBN 24046929 ATTORNEYS FOR THE STATE The State does not request oral argument. TABLE OF CONTENTS INDEX OF AUTHORITIES iv-v STATEMENT OF THE CASE vi-viii STATEMENT OF FACTS 1-10 SUMMARY OF THE STATE’S ARGUMENTS 11-12 STATE’S REPLY TO APPELLEE’S ISSUES PRESENTED: 13-36 REPLY TO ISSUES ONE AND THREE: The sole basis for the trial court’s grant of writ relief was its conclusion that Reyes’s trial counsel rendered ineffective assistance of counsel by failing to properly advise him of the immigration consequences of his guilty plea as required by Padilla v. Kentucky. Additionally, the trial court’s statements and actions indicate that it rejected and impliedly denied Reyes’s other non-Padilla writ grounds. Consequently, the Eighth Court did not err in considering Reyes’s other grounds to have been rejected or impliedly denied by the trial court. Moreover, none of the trial court’s findings and conclusions showed that the trial court intended to grant relief on Reyes’s other non-Padilla writ grounds. And findings and conclusions on those other writ grounds was not essential or potentially dispositive to the issue the State appealed to the Eighth Court. Therefore, the Eighth Court did not err to any extent that it did not remand the case for findings and conclusions on Reyes’s other writ grounds. 13-33 REPLY TO ISSUE TWO: The Eighth Court did not err in determining that the sole basis for the grant of any writ relief by the trial court was Reyes’s Padilla claim and that the trial court impliedly denied the rest of Reyes’s writ grounds. And in so determining, the Eighth Court did not deprive Reyes of the opportunity to obtain appellate review of the trial court’s decision not to grant relief on his other non-Padilla writ grounds, as article 11.072, section 8 of the Code of Criminal Procedure allows a writ applicant to appeal a partial denial of his writ application. 34-36 PRAYER 37 ii SIGNATURES 37-38 CERTIFICATE OF COMPLIANCE 37 CERTIFICATE OF SERVICE 38 iii INDEX OF AUTHORITIES FEDERAL CASES Chaidez v. United States, ---U.S.---, 133 S.Ct. 1103, 185 L.Ed.2d 149 (2013).... 19 Padilla v. Kentucky, 559 U.S. 356, 130 S.Ct. 1473, 176 L.Ed.2d 284 (2010)...... 23 Roe v. Flores-Ortega, 528 U.S. 470, 120 S.Ct. 1029, 145 L.Ed.2d 985 (2000).... 23 Strickland v. Washington, 466 U.S. 668, 104 S.Ct. 2052, 80 L.Ed.2d 674 (1984).............................................. 25 STATE CASES Cannon v. State, 252 S.W.3d 342 (Tex.Crim.App. 2008).................... 25 Ex parte Chavez, 371 S.W.3d 200 (Tex.Crim.App. 2012)................ 17, 26 State v. Cullen, 195 S.W.3d 696 (Tex.Crim.App. 2006)..................... 28 Ex parte De Los Reyes, 392 S.W.3d 675 (Tex.Crim.App. 2013).............. 19 State v. Elias, 339 S.W.3d 667 (Tex.Crim.App. 2011)................... 28-29 Gottson v. State, 940 S.W.2d 181 (Tex.App.–San Antonio 1996, pet. ref’d)..... 26 Johnson v. State, 414 S.W.3d 184 (Tex.Crim.App. 2013)................... 32 State v. Kelley, 20 S.W.3d 147 (Tex.App.–Texarkana 2000, no pet.)................................................. 15-16, 20, 35 State v. Mazuca, 375 S.W.3d 294 (Tex.Crim.App. 2012)................. 29, 32 McDonald v. State, No. 08-08-00103-CR, 2010 WL 3910424 (Tex.App.–El Paso, Sept. 30, 2011, pet. ref’d) (not designated for publication).................................... 25-26 iv State v. Mendoza, 365 S.W.3d 666 (Tex.Crim.App. 2012)................... 29 Miller v. State, 83 S.W.3d 308 (Tex.App.–Austin 2002, pet. ref’d).... 15-16, 20, 35 Montanez v. State, 195 S.W.3d 101 (Tex.Crim.App. 2006).......... 15-16, 20, 35 Murphy v. State, 112 S.W.3d 592 (Tex.Crim.App. 2003).................... 25 Rey v. State, 897 S.W.2d 333 (Tex.Crim.App. 1995)............... 15-16, 20, 35 Ex parte Reyes, No. 08-12-00261-CR, 2014 WL 2993789 (Tex.App.–El Paso, June 30, 2014, pet. granted) (not designated for publication)........... 16, 22, 35 Rylander v. State, 101 S.W.3d 107 (Tex.Crim.App. 2003)................... 25 STAT
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.R. 876, 878 (Bankr. W.D.Tenn.2004); 4 Keith M. Lundin, Chapter 13 Bankruptcy § 350.1 at 350-2 (3d ed. 2004) ("A plan that does not... make any mention of the payment of postpetition claims does not provide for such claims....") However, § 1322(b)(6) is permissive, not mandatory. It allows a plan to give special treatment to postpetition claims (payment of "all or any part" of the claim) distinct from the treatment of prepetition claims, but it does not require special treatment of postpetition claims for those claims to be paid.[6] By providing *527 generally for payment of allowed priority claims, the debtor's plan encompasses all allowed priority claims, whether they involve taxes or other obligations, and whether they arose prepetition under § 501 or postpetition under § 1305.[7] 3. The absence of an objection. A central feature of the claims allowance process is that once a proof of claim is filed, the claim is treated as allowed unless an objection is filed. This rule is stated quite clearly in § 502(a): "A claim... proof of which is filed under section 501 of this title, is deemed allowed, unless a party in interest... objects." Thus, without an objection, a Chapter 13 trustee cannot treat a filed claim as disallowed. In re Jones, 271 B.R. 397, 401 (Bankr.S.D.Ala. 2000) ("[T]he trustee cannot unilaterally override a proof of claim."). Section 1305 creates no different rule for postpetition claims. To the contrary, § 1305(b) expressly provides that claims within the scope of the section "shall be allowed or disallowed under section 502 of this title"—thus requiring postpetition claims, in the absence of objection, to be treated as allowed. The trustee therefore acted improperly in treating the IRS claim as disallowed for untimeliness in the absence of a claim objection on that ground. However, in response to the debtor's motion, the trustee set out her reasons for believing that the IRS claim should be disallowed, the trustee provided notice to the IRS, and the parties have treated this response as a claim objection, fully briefing the issue of timeliness. Under these circumstances, the debtor (and the IRS) waived the requirement that the trustee file a formal claim objection, and the merits of the parties' dispute can properly be adjudicated. Cf. In re Pence, 905 F.2d 1107, 1109 (7th Cir.1990) (holding that the requirement of an adversary complaint is not a jurisdictional defect and could be waived by the opposing party). 4. The debtor's "adoption" of the IRS claim. As an alternative to her contention that the IRS claim was not untimely, the debtor's motion requests in the alternative (1) that she be given leave to "adopt" the IRS claim and (2) that her time for filing proof of this claim under Fed. R. Bankr.P. 3004 be extended retroactively. This proposal attempts to avoid the question of whether the IRS timely filed its proof of claim by exploiting a disparity in the bankruptcy rules. Fed. R. Bankr.P. 9006(b)(3), as discussed below (at n. 10), strictly limits the extent to which a court may extend the deadlines set forth in Fed. R. Bankr.P. 3002(c) for creditors to file proofs of their own claims, but it places no limit on the extent to which a court may extend the deadline set forth in Fed. R. Bankr.P. 3004 for debtors to file proofs of claims on behalf of creditors. The deadline for the debtor to file is instead subject only to the *528 general provisions of Rule 9006(b)(1), which allow retroactive extension of deadlines "where the failure to act was the result of excusable neglect." This approach, however, is unavailing, since the debtor cannot "adopt" the IRS claim. Section 501(c) allows a debtor to file proof of a "creditor's" claim if the creditor does not timely do so, but as discussed above (at n. 1), only holders of prepetition claims are generally defined as "creditors" under the Code, and so § 501(c) does not apply to postpetition claims. Section 1305, in turn, contains no provision parallel to § 501(c). To the contrary, under the express provisions of § 1305(a), only the entity holding a postpetition claim against the debtor is authorized to file the proof of claim. In re Epstein, 200 B.R. 611, 614 (Bankr. S.D.Ohio 1996) (collecting authorities holding that a debtor may not file proof of a § 1305 claim for a creditor). And, of course, the right to file a § 1305 claim must be limited to the postpetition creditor holding the claim if the creditor is to be accorded the option of allowing the claim to pass through bankruptcy unaffected by the debtor's plan. Thus, if § 1305 claims are subject to filing deadlines, a debtor cannot avoid those deadlines by filing a proof of claim on a creditor's behalf. B. The timeliness of the IRS claim. Since the preliminary matters do not dispose of the debtor's motion, it is necessary to consider the trustee's argument that the IRS claim should be disallowed as untimely. This argument is based on a literal application of § 502(b)(9) to the claim. Section 502(b)(9) provides that a claim shall be disallowed if "proof of such claim is not timely filed" and goes on to give governmental units 180 days after the filing of a voluntary bankruptcy case to file a proof of claim, unless the Federal Rules of Bankruptcy Procedure provide a longer period.[8] The relevant rule—Fed. R. Bankr.P. 3002(c)(1)—adds little to this provision. It states simply: A proof of claim of a governmental unit is timely filed if it is filed not later than 180 days after the date of the order for relief. On motion of a governmental unit before the expiration of such period and for cause shown, the court may extend the time for filing of a claim by the governmental unit. Applying these time limits to the IRS claim would, as the trustee contends, render the claim untimely filed. This case was filed (generating the order for relief) on July 8, 2002; the 180th day thereafter was January 4, 2003. The IRS did not ask for an extension of the deadline before this date, and its proof of claim was filed much later, on March 24, 2004. A literal application of § 502(b)(9) to claims under § 1305 would ordinarily be required. See United States v. Ron Pair Enterprises, Inc., 489 U.S. 235, 241, 109 S.Ct. 1026, 103 L.Ed.2d 290 (1989) ("The plain meaning of legislation should be conclusive, except in `rare cases [in which] the literal application of a statute will produce a result demonstrably at odds with the intentions of its drafters.'"). In the present *529 situation, however, "plain meaning" does produce genuinely anomalous results. As to prepetition claims, the filing deadlines of § 509(b) and the bankruptcy rules, though stringent, are a reasonable balance between the need for prompt administration of a bankruptcy case and a fair opportunity for the claimant to file. Applied to postpetition claims, however, these deadlines are patently unreasonable, as the present case illustrates. Even with perfect efficiency and access to all relevant information, the IRS could not determine whether the debtor was liable for 2002 income taxes until the tax year closed and the debtor's withholding could be compared to her taxable income. The tax year closed on December 31, 2002, only four days before the 180-day deadline expired. Moreover, the IRS could not realistically assess the debtor's tax liability until the time for filing her return had passed, and that date (April 15, 2003) was three months after the expiration of the 180-day deadline.[9] The problem created by applying the claims-filing deadlines to § 1305 is not limited to tax claims. For non-governmental claims, an even shorter deadline applies. Fed. R. Bankr.P. 3002(c) requires these claims to be filed within 90 days after the first date set for the meeting of creditors under § 341 of the Code. Since Fed. R. Bankr.P.2003(a) requires that meeting to be set between 20 and 50 days after the case filing, the non-governmental filing deadline is between 110 and 140 days after case filing. And this deadline—unlike the one for governmental claims—cannot be extended.[10] Under circumstances like these, the plain meaning rule is not inexorable. "Courts are not required to follow literal language where it would produce an outcome at odds with the purpose of Congress and where the result stems merely from an unintended quirk in drafting." Nelson v. Scala, 192 F.3d 32, 35 (1st Cir.1999) (rejecting literal application of § 522(f)(2) of the Bankruptcy Code); accord Lehman *530 v. VisionSpan, Inc. (In re Lehman), 205 F.3d 1255, 1257 (11th Cir.2000). This exception is applicable here. Applying the filing deadlines to claims under § 1305 actually produces two different results that could not have been intended. The first is automatic disallowance of most of the claims that § 1305 authorizes. Chapter 13 plans generally provide for payments from the debtor for a period lasting between three and five years, see 11 U.S.C. § 132
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The post you just read through can aid you do this, but you should be inclined to put these tips to motion in purchase to safe a coverage.--- abstract: 'We propose BMLE, a new family of bandit algorithms, that are formulated in a general way based on the Biased Maximum Likelihood Estimation method originally appearing in the adaptive control literature. We design the cost-bias term to tackle the exploration and exploitation tradeoff for stochastic bandit problems. We provide an explicit closed form expression for the index of an arm for Bernoulli bandits, which is trivial to compute. We also provide a general recipe for extending the BMLE algorithm to other families of reward distributions. We prove that for Bernoulli bandits, the BMLE algorithm achieves a logarithmic finite-time regret bound and hence attains order-optimality. Through extensive simulations, we demonstrate that the proposed algorithms achieve regret performance comparable to the best of several state-of-the-art baseline methods, while having a significant computational advantage in comparison to other best performing methods. The generality of the proposed approach makes it possible to address more complex models, including general adaptive control of Markovian systems.' author: - | Xi Liu[^1]\ Electrical and Computer Engineering\ Texas A&M University\ `[email protected]`\ Ping-Chun Hsieh$^{*}$\ Department of Computer Science\ National Chiao Tung University\ `[email protected]`\ Anirban Bhattacharya\ Department of Statistics\ Texas A&M University\ `[email protected]`\ P. R. Kumar\ Electrical and Computer Engineering\ Texas A&M University\ `[email protected]` bibliography: -'reference.bib' title: | Bandit Learning Through\ Biased Maximum Likelihood Estimation --- [^1]: Equal contribution. Effect of second pregnancy on maternal carriage and outcome of high-risk human papillomavirus (HPV). Experience from the prospective finnish family HPV study. The effect of second pregnancy on human papillomavirus (HPV) carriage and outcome is modelled in longitudinal setting covering two subsequent pregnancies. Among 329 (baseline pregnant) women prospectively followed up in the Finnish Family HPV Study, two subcohorts were compiled: (i) 78 women (Group B) who became pregnant for the second time during the follow-up, and (ii) 100 women (Group A) who did not develop 2nd pregnancy. The effect of pregnancy on high-risk HPV (HR-HPV) carriage and outcome was analysed using Kaplan-Meier and Cox survival analyses and generalized estimating equation (GEE) modelling of the longitudinal data. Women in the two groups were similar in their baseline HR-HPV status but significantly different in several known risk factors of HR-HPV infection. Group A women showed higher point prevalence of cervical and oral HR-HPV at the 36-month (p = 0.015) and 6-month (p = 0.024) follow-up visit, respectively. Among Group B women, prevalence of both cervical and oral HR-HPV significantly decreased during 2nd pregnancy (p = 0.005 and p = 0.002) as compared with inter-pregnancy period, but increased again after 2nd pregnancy. There was no difference in acquisition or clearance of cervical or oral HR-HPV between the two groups in univariate (Kaplan-Meier) or multivariate (Cox) survival analysis. In the GEE approach, 2nd pregnancy was not significantly associated with cervical or oral HR-HPV carriage or persistence when adjusted for all other covariates. Second pregnancy is of little impact on carriage and persistence of oral and cervical HR-HPV infections in a longitudinal setting over time.Microwave-assisted synthesis of porous chitosan-modified montmorillonite-hydroxyapatite composite scaffolds. In this study, a porous chitosan-organically modified montmorillonite-hydroxyapatite (CS-OM-HA) composite scaffold was developed by combining microwave irradiation and gas foaming method. Hydroxyapatite (HA) particles of size ∼ 65 nm were synthesized and characterized by X-ray diffraction (XRD) and attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy. The prepared composite scaffolds were characterized using ATR-FTIR, XRD, mercury intrusion porosimeter (MIP) and scanning electron microscopy (SEM) studies. The synergistic effect of HA and OM on the mechanical and in vitro biological properties (swelling, degradation, protein adsorption and bioactivity) of the composite scaffolds were evaluated. Swelling, degradation, mechanical property, bioactivity and protein adsorption studies of CS-OM-HA composite scaffolds have shown desirable results in comparison with the pure CS and CS-OM composite scaffolds. CS-OM-HA composite scaffolds were also found to be non-cytotoxic to MG 63 osteoblast cell lines. From the study, it can be concluded that the novel CS-OM-HA composite scaffold with improved mechanical and in vitro biological properties has wide potential in non-load bearing bone tissue engineering applications.不同类型情绪对认知抑制的影响The Effects of Emotion on Cognitive Inhibition 本研究采用3(情绪类型：正性、负性、中性)× 3(任务类型：一致、不一致、无关)的被试内实验设计，考察了情绪对认知抑制的影响。以38名大学生为被试，从中国情绪图片库中选取正性、负性和中性图片各60张，并在stroop任务前呈现情绪图片，要求被试判断stroop任务中的汉字颜色。结果发现，任务类型主
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, Nipsey, what do you get when you cross a lady driver with a with a Vietcong" "I don't know, Dickie." "What do you get when you cross a lady driver with a Vietcong?" "A hundreed thousands senseless days." "Do it to it." "Do it to it." "Do it to it." "Do it to it." "Now, as you know, Nipsey..." "I'm the first streaker." "Streaking's the new thing." "We touched penises." "We interrupt this program to bring you an NBC news special report." "From Rockefeller center," "Chet Huntley and David Brinkley." "Good evening." "NBC news has learned that less than an hour ago there was an explosion aboard the Apollo 13 spacecraft." " David?" " Thank you, Chet." "Chet?" "Thank you, David." "We are awaiting further information." "David?" "Thank you, Chet." "Let's go to the manned space center in Houston and our reporter on the scene, Mr. Jamie Garnett." "Jamie?" "Thank you, Chet and David." "I'm sorry, sweetheart, could you move out of the way of our camera?" "We need to talk to our new reporter there, Jamie Garnett." "Now, where is he?" "I'm Jamie Garnett, gentlemen." "I spoke earlier with NASA flight director Glynn Lunney..." "Listen, doll, you're not making any sense." "You're probably hysterical from menstruation." "Go lie down and make sure you get plenty of iron." "Maybe eat a ham salad..." "Also I'm being told that commander James Lovell..." "Honey, you have a dynamite shape, but you're going to have to shut up and let a man tell us what's happening." "Now, is your father or a policeman nearby?" "Now, where did you find that microphone, sugar mouth?" "Was it just lying there on the ground?" "Where is Jamie Garnett?" "This just in, the NBC male news reporter Jamie Garnett is missing." "I'm right here you mother..." "Classic live television." "And while they never found Jamie Garnett, that woman who stole his microphone went on to become a wife." "Has Paul not come back?" "He's not answering his phone." "What have I done?" "Calm down." "Paul's gone, but you're getting proposed to on the show tonight." "By me." "This is New York state bitch, anyone can marry anything now." "What?" "But..." "Oh come on, think what great TV this will be." "It's everything you want." "No, it's not." "Paul is everything I want." "He's the reason to get married, not TV." "Rick Santorum was right." "How could I have been so blind?" "Because you're a horrible person." "Thank you." "Just portion control and lots of water." "All in favor of keeping "TGS" live?" "It's still not unanimous." "And it never will be." "This is a business, Kenneth, and if live TV went away, the only thing that would change would be NBC's profit margin." "That's not true, Jackie D." "Live TV changed my life." "In 1986 my church dance crew performed on a regional telethon." "It was my big break." "Flashback." "This is for you, Jesus." "♪" "Ow, my coccyx!" "It's not funny." "Coccyx is the scientific term for your butt bone." "Why are you all laughing?" "I like it." "Coccyx." "Coccyx." "Hey, what do you call this?" "This is the garry-o-many core." "Oh, my God." "I remember that." "That was you?" "That's when I realized I was a ridiculous man." "Tracy, I was there." "As a lower-level GE employee," "I was answering phones at that telethon." "When you took off your clothes, they cut to the phone banks." "Gasp." "I made a hilarious prank call to that telethon." "Wait, did the man who answered sound like he had the piercing blue eyes of an ice dragon?" "Yes." "Hello, I'd like to speak to General Electric." "Madam," "I'm afraid you're confused." "I was a nurse in the war and I met him when he was just a colonel." "He's the father of my child." "General Electric is not a person." "Toby, come talk to your father." "Daddy, it's your son, Toby Electric." "Alright, whoever this is, no one, no one jokes down General Electric." "Yeah, except your mom last night." "If I ever get my thick," "manly hands on you," "I will roast you alive in an oven I design myself, using two, no, three kinds of heat." "I'm Jack Donaghy, damn it." "Watching you get all red-faced on TV, that was the night I found my calling..." "Sticking it to the man." "You know what?" "That night changed my life, too." "Don Geiss saw my loyalty/handsomeness and the next day he promoted me out of poisons and into microwaves." "Live TV made us all what we are today." "No need to take another vote." ""TGS" is meant to be live." "To make it more profitable, we'll just do more sponsor product placements you should do it with the upcoming Warner Brothers movie," ""Rock of ages," based on the hit Broadway musical." "Rocking a theater near you June 15th." "Tom Cruise sings." "Or I'll just pay you all less." "Kenneth, let us out of here." "Paul didn't come." "I ruined everything." "Yeah, you blew it." "So I'll just jump out at some point and lez it up with you?" "Okay." "We're on in five, four, three, krang..." "And now, "Prince William and Prince time travelling fart detectives"." "Ha, take that, The Man!" "Prince, do you smell something fishy?" "Who's that dude?" "♪ Zou bisou bisou ♪" "♪ Zou bisou bisou ♪" "♪ Zou bisou bisou ♪" "Jenna Maroney, you're the woman I want to grow old with." ""Old" being an acronym for oxylaprodexatrin, a hallucinogenic plant extract that makes sex terrifying." "I want to spend the rest of my life making you happy." "That's why I'm asking you, on TV, to marry me." "Oh, Paul." "No, no, a million times no." "Not like this." "I was wrong." "You were right." "I don't want to get married for publicity." "I want to get married for you." "And so you can't testify against me in court." "I still don't know what's going on." "Wow." "Wow, 2.5 million people just saw that." "And now 14 million people saw it." "You're welcome, oh and also I broke your toilet." "Thank you to Lorne Michaels, Jon Hamm, Kim Kardashian," "Brian Williams, Jimmy Fallon, Amy Poehler, Fred Armisen..." "SNL crew, I love you, 30 ROCK crew, I love you." "Watch "Parks and Rec" tonight directed by Amy Pohler."Q: Convert PHP array string into an array I have an array: $myArray = array('key1'=>'value1', 'key2'=>'value2'); I save it as a variable: $fileContents = var_dump($myArray); How can convert the variable back to use as a regular array? echo $fileContents[0]; //output: value1 echo $fileContents[1]; //output: value2 A: I think you might want to look into serialize and unserialize. $myArray = array('key1'=>'value1', 'key2'=>'value2'); $serialized = serialize($myArray); $myNewArray = unserialize($serialized); print_r($myNewArray); // Array ( [key1] => value1 [key2] => value2 ) A: serialize might be the right answer - but I prefer using JSON - human editing of the data will be possible that way... $myArray = array('key1'=>'value1', 'key2'=>'value2'); $serialized = json_encode($myArray); $myNewArray = json_decode($serialized, true); print_r($myNewArray); // Array ( [key1] => value1 [key2] => value2 ) A: Try using var_export to generate valid PHP syntax, write that to a file and then 'include' the file: $myArray = array('key1'=>'value1', 'key2'=>'value2'); $fileContents = '<?php $myArray = '.var_export($myArray, true).';?>'; //... after writing $fileContents to'myFile.php' include'myFile.php'; echo $myArray['key1']; // Output: value1 2014 Sundance
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worked with Topel to arrange for the priest to come hastily to Seattle to prevent a scandal from erupting in Spokane. Furthermore, they claim that the archdiocese, under Hunthausen's leadership, was negligent by not properly vetting O'Donnell before he came to St. Paul. But the archdiocese's lawyers say Hunthausen — and others in the archdiocese — were never told about O'Donnell's history, nor that he was being treated for a sexual attraction to boys. They believed the priest was in Seattle for graduate school. Furthermore, the lawyers say, the archdiocese received approval through a phone call from Topel for O'Donnell to serve in Seattle — though neither Topel nor the archdiocesan leader who received the call can testify since both are deceased. Of the original four plaintiffs in the lawsuit, the two who went to trial here last week had previously settled over the same abuses with the Spokane Diocese and the Catholic order that ran the seminary where O'Donnell attended, archdiocese attorney Michael Patterson had said earlier. During his years as Seattle's archbishop, Hunthausen, among other things, withheld part of his income tax to protest the nuclear arms buildup, gave women a broader role in church leadership, and opened St. James Cathedral for a Mass celebrated by a national gay Catholic group. After critics wrote to the Vatican saying the archbishop was deviating too much from church teachings, the Vatican investigated and ordered Hunthausen to temporarily share power with an auxiliary bishop.Nursing diplomas can be bought for as little as £43 in the Philippines, I can reveal today. Doubts about Victorino Chua’s qualifications emerged after this newspaper alerted police to suspicions over his credentials back in 2012. And – helped by my photographer colleague Jamie Wiseman - I have found there is a rampant trade in bogus exam certificates in Manila, with fixers and forgers always on hand to fabricate any document. Scroll down for video Reporter Stephen Wright has uncovered a rampant trade in bogus exam certificates being sold in Manila. He managed to obtain all the documents he needed to work abroad for £43 - including a fake graduation photo Stephen was also given a fake identification card by a fixer who advised him how to obtain work in the UK He was also given a fake degree certificate (pictured) after visiting Recto Avenue in downtown Manila The Mail’s revelations are a major embarrassment to ministers, hospital chiefs and officials at the Nursing and Midwifery Council, which regulates nursing. In March 2013, the council imposed a temporary recruitment freeze on foreign nurses amid fears that workers could have faked documents to get jobs here. Yet hundreds of nurses are still being recruited from the Philippines by NHS trusts, because of a massive shortfall of staff. The ‘passport’ to a nursing job in the UK is provided by organised crime networks who employ some of the world’s best forgers. On Recto Avenue in downtown Manila are stalls openly offering fake nursing degrees, education records, diploma pictures, police clearance to work overseas, passports, driving licences and birth and marriage certificates. Police turn a blind eye in return for bribes. When Stephen visited Recto Avenue, dubbed ‘Xerox Alley’, a fixer for the forgers went through a list of documents required to become qualified - all of which were easily obtained The fixer (pictured) even helpfully suggested which date he should graduate from Manila’s respected nursing college at Our Lady of Fatima University When I visited Recto Avenue, dubbed ‘Xerox Alley’, a fixer for the forgers went through a list of documents I would require to become qualified, including a degree certificate, police clearance to work overseas and employment certificates and references. All these were supplied for a total of £43. The fixer even helpfully suggested which date I should graduate from Manila’s respected nursing college at Our Lady of Fatima University. Of course, the vast majority of Filipino nurses are qualified and have the correct credentials to work in the UK. In this impoverished nation struggle to find the money to finish their degree courses and are tempted to buy their qualifications they need to obtain work in the UK where salaries are vastly higher But many in this impoverished nation struggle to find the money to finish their degree courses and are tempted to buy their qualifications they need to obtain work in the UK where salaries are vastly higher. In the run-up to yesterday’s court verdicts, NMC chief executive Jackie Smith told the Mail its vetting system was now ‘robust’ and that her staff insisted on seeing original education documents from prospective foreign nurses. But a source close to the Stepping Hill case said: ‘Vetting of nurses in the Philippines is very, very poor. A lot is done on the word of the Philippines regulatory authorities. ‘They rely on stamped documents as proof of proper qualifications. This is why police can’t be certain that Chua’s qualifications are genuine.’ Another said: ‘We can’t be certain that the Philippines’ Professional Regulation Commission has exercised due diligence with regard to the NHS. Once you have a PRC stamp, you are more or less guaranteed a job in the UK.’However, a clever California judge ruled that he did not have enough factual evidence to support his case and dismissed the lawsuit using Swift's lyrics from "Shake It Off," "Blank Space," "Bad Blood" and "We Are Never Ever Getting Back Together" to do so. "At present, the Court is not saying that Braham can never, ever, ever get his case back in court," the judge wrote, according to CNN. "But, for now, we have got problems, and the Court is not sure Braham can solve them." She continues, "As currently drafted, the Complaint has a blank space--one that requires Braham to do more than write his name. And, upon consideration of the Court's explanation... Braham may discover that mere pleading BandAids will not fix the bullet holes in his case. At least for the moment, Defendants have shaken off this lawsuit."Track Listing: After Several Snowstorms; Sometimes It's Hard to Get Dressed in the Morning; Let's Say It Comes in Waves; Life's Hurtling Passage Onward; What Can Be Set to the Side; What's Equal to What; Melio Melo.A dark-haired beauty with a heart-shaped face and a brilliant coloratura voice, Grayson signed with MGM as a teenager and made her screen debut in "Andy Hardy's Private Secretary," starring Mickey Rooney, in 1941. She went on to appear opposite Frank Sinatra and Gene Kelly in "Anchors Aweigh," Kelly in "Thousands Cheer," Sinatra in "The Kissing Bandit," Mario Lanza in "The Toast of New Orleans," Howard Keel in "Show Boat," "Lovely to Look At" and "Kiss Me Kate," and Gordon MacRae in "The Desert Song," among other musicals. "Kathryn Grayson was an attempt to continue the Jeanette MacDonald tradition at MGM," said Drew Casper, a professor at USC's School of Cinematic Arts, referring to half of the studio's popular operetta team of Jeanette MacDonald and Nelson Eddy who came to fame in the 1930s. "In all her films, Grayson was always doing an opera aria as a specialty number," Casper said. But MGM didn't revive operetta until the late 1940s when it signed Mario Lanza, and could have someone play opposite Grayson, a la Nelson and MacDonald, he said. Grayson and Lanza made only "That Midnight Kiss" and "The Toast of New Orleans" together. She then was teamed with Keel. Grayson's favorite leading man, it turns out, was Lanza. "He was great," she told the Toronto Star in 1994, "but I could have murdered him for scene stealing." Grayson had no fond memories of "The Vagabond King," her final big-screen musical, for Paramount, in 1956. "I didn't like it," she told the Toronto Star. "So I called it a day: no more movies." At the conclusion of her film career, Grayson began performing in nightclubs and concerts and did some acting on television, including appearances on "General Electric Theater" and "Playhouse 90." In 1960, she made her opera debut, in "Madama Butterfly." She replaced Julie Andrews as Guenevere in the original Broadway production of "Camelot" in 1962 and toured in the musical for more than a year -- as well as touring in "Naughty Marietta," "Showboat," "Kiss Me Kate" and other productions. In 1988, she began touring in a one-woman show, "An Evening with Kathryn Grayson." She was born Zelma Hedrick in Winston-Salem, N.C., on Feb. 9, 1922, and later moved with her family to St. Louis, where she was discovered singing on the empty stage of the St. Louis Municipal Opera House at age 12 and introduced to a vocal teacher. She was training for a career in opera when she was signed by MGM. Grayson, who was married and divorced twice -- to actor John Shelton and to singer Johnny Johnston -- is survived by
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already had been substantially delayed during the several months that Williams remained a fugitive. Further, Williams waited until the morning of trial to state his request for a jury trial, although he could have made this request at any time during the two-month period after the court granted his November 1997 continuance motion. Williams made his request shortly after the trial was to begin on Wednesday, January 21, 1998. The circuit court informed the parties that if the case were to be tried by a jury, "it may take several hours to begin the case." Thereafter, Williams restated his request for a jury trial, and the Commonwealth's attorney opposed the request, informing the court that she intended to call 11 witnesses to testify in the case. She further stated that Khan, the robbery victim, was leaving the United States the following Monday to return to his native country for three months. Under these facts, the circuit court was presented with the prospect that selection of a jury could not begin until late that day, Wednesday afternoon. Given the number of witnesses that the prosecution intended to call in the case, the court had no assurance that the trial could have been concluded before Monday, when Khan intended to leave the country for a three-month period. Moreover, even if the Commonwealth's attorney presented Khan's testimony early in the case, there remained the possibility that Khan would be required as a rebuttal witness near the end of the trial. Based on these facts and circumstances, the record shows that if Williams had been allowed to withdraw his jury trial waiver and be tried by a jury, completion of the trial could have been substantially delayed and the cause of justice impeded. Therefore, we conclude that the circuit court did not abuse its discretion in denying Williams' request to be tried by a jury. For these reasons, we will reverse the Court of Appeals' judgment and reinstate Williams' convictions in accordance with the circuit court's judgment order. Reversed and final judgment. INTRODUCTION {#SEC1} ============ In the process of gene transcription cooperative interactions between transcription factors (TFs) and DNA methylation play an important role in regulating gene expression. The classical view of TF--DNA interaction is that TFs usually bind to non-methylated DNA motifs in open chromatin regions, whereas high level of methylation at CpG dinucleotides (mCpG) in the cis-regulatory elements prohibits recruitment of TFs, except only a few proteins with a mCpG-binding domain (MBD), including MeCP2, MBD1, MBD2 and MBD4. These MBD proteins are known to recognize methylated DNA in a sequence-independent manner ([@B1],[@B2]). However, several TFs without MBDs were found to interact with methylated DNA in sporadic studies previously. For example, transcription factor KLF4 ([@B3]), Kaiso ([@B4]), ZFP57 ([@B5]) and CEBPα ([@B6]) were identified with high affinity to distinct methylated DNA sequences. More recently, systematic efforts have revealed that hundreds of TFs could specifically bind to methylated DNA by means of tandem mass spectrometry ([@B7]), functional protein microarray ([@B3]), DNA microarray ([@B8]), systematic evolution of ligands by exponential enrichment (SELEX) ([@B9]) and ChIP-BS-seq ([@B10]). Identification of such TFs and elucidation of their functions become important stepping stones towards understanding the mechanism underlying these methylation-mediated biological processes, leading to crucial implications for human diseases and cancer. Over the past 30 years, many databases have been constructed to archive information of TF binding sites, providing invaluable resources for the transcription community and beyond. For instance, TRANSFAC ([@B11]), JASPAR ([@B12]) and UniPROBE ([@B13]) are the most common open-access databases containing hundreds of transcription factor position weight matrices (PWMs) constructed from DNA binding sequences. The PWMs can help search and predict potential TF binding sites in the whole genome. Meanwhile, TF regulatory activity has been known as biological species-dependent. Hence, lots of species-specific TF databases were created, such as PlantTFDB for plant ([@B14]), AnimalTFDB for Animal ([@B15]) and ITFP for human, mouse and rat ([@B16]). Some databases such as TFBSshape ([@B17]) not only contain extensive nucleotide sequences of TFs, but also calculate DNA structural features from nucleotide sequences provided by motif databases. Unfortunately, none of these databases records methylated DNA binding sites for TFs. With the advance of next generation sequencing technologies, DNA methylation sites can be determined at the single base pair resolution. A number of systematical DNA methylation databases have been developed for epigenetic studies. As the first DNA methylation database, MethDB stores DNA methylation data and gene expression information ([@B18]). NGSMethDB archives DNA methylation profiles generated from bisulfite sequencing technique ([@B19]). MethBank ([@B20]), MethyCancer ([@B21]) and MENT ([@B22]) focus on DNA methylation status of some specific biological problems, such as embryonic development and multifarious cancers. MethSMRT hosts the DNA N6-methyladenine and N4-methylcytosine methylomes ([@B23]). ENCODE database also contains many datasets of Whole Genome Bisulfite Sequencing (WGBS) and ChIP-Seq datasets obtained from many cell lines. These databases provide us with a large amount of profiles including TFs binding sequences and corresponding DNA methylation status. However, none of the existing databases systematically documents the interactions between TFs and methylated DNA sequences. To fill this gap for the researchers to better understand the interactions between DNA methylation and TFs, we collected information about methylated DNA--TF interactions from two major public sources: published literatures and ENCODE database. We developed a database, dubbed as MeDReaders, where 753 methylated DNA--TF interactions involving 731 TFs were manually curated from the literature. A total of 292 TFs were predicted to bind to distinct methylated and unmethylated DNA motifs based on integration of WGBS data and ChIP-Seq data in six human cell lines and one mouse cell line extracted from ENCODE and GEO database. MeDReaders can help the scientists to compare methylated DNA binding activities between different species and datasets, and further understand the biological processes that are mediated by DNA methylation. The MeDReaders is publicly available at <http://medreader.org/> without use restriction. MATERIALS AND METHODS {#SEC2} ===================== Data sources {#SEC2-1} ------------ To extract experimentally confirmed methylated DNA--TF interactions from the published literatures, we first searched all relevant papers from the PubMed literature database. CEBPα ([@B3],[@B6]), ZFP57/KAP1 ([@B5],[@B24]), ZBTB33 ([@B4]), CEBPB/ATF4 ([@B25]) were found to interact with methylated DNA using EMSA or ChIP-BS-seq experiments. Hundreds of TFs were identified to prefer CpG-methylated sequences by high-throughput technology, such as Tandem mass spectrometry (MS/MS) ([@B26],[@B27]), protein microarray ([@B3]), methylation-sensitive SELEX ([@B9]). In total we manually curated 753 methylated DNA--TF interactions involving 731 TFs from 4 human cell lines/tissues and 4 mouse cell lines/tissues (Table [1](#tbl1){ref-type="table"}). However, the retrieved records are different due to diverse methods in individual experiments. For example, using SELEX *in vitro*, we only got TF binding motifs instead of binding sequences. But we obtained some protein binding DNA sequences from protein arrays, where methylated binding motif logos for only a few specific TFs can be retrieved. ###### Transcription factors summarized from published literatures Species No. of TFs No. of cells/tissues --------- ------------ ---------------------- Human 601 4 Mouse 130 4 Another way to access the interaction between TFs and methylated DNA sequences is to re-analyze the datasets from the ENCODE Consortium and NCBI GEO by focusing on the methylation levels of TF binding regions. We downloaded WGBS data for four human cell lines, ChIP-Seq data for six human and one mouse cell lines from the ENCODE, and WGBS data of ES-E14, IMR-90 and HCT116 cell lines and ChIP-Seq of ES-E14 cell from the GEO with accession numbers GSM1027571, GSM2210597, GSM1465024 and GSM699165 (Table [2](#tbl2){ref-type="table"}). All datasets were re-processed using the ENCODE standard pipeline. In summary, Bismark ([@B28]) was used for the WGBS data analysis to align sequencing reads then call methylation levels, while the Irreproducible Discovery Rate method ([@B29]) was employed for ChIP-Seq data to call the TF binding peaks. ###### Transcription factors inferred by WGBS and ChIP-Seq datasets Species Cell/tissue No. of TFs --------- ------------- ------------ Human GM12878 44 Human H1-hESC 33 Human HepG2 89 Human HCT116 5 Human IMR-90 6 Human K562 110 Mouse E14 5 Sequence motifs containing methylated sites {#SEC2-2} ------------------------------------------- The same computational method described in our published paper ([@B30]) was adopted to predicted methylated and unmethylated motifs of TFs by integrating WGBS and ChIP-Seq data. DNA sequences within each ChIP-Seq peak were extracted and grouped based on their average methylation level. The MEME ([@B31]) algorithm was used to predict
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of matter down to my core, Make me all the particles I'm made of, So who am I? What am I? The next time someone ask you "What Are You" or "Who Do you think you are, you know the type" Reply: **I am what I am and I'm okay with that and I am who I am and I'm okay with that too...** ** ** **I WANT** I want to be with him on this stormy day, Wrapped up in his arms or him wrapped up in mine, Watching the movies we enjoy, Or just watching his eyes in competition with mine to see who can hold the longest stare, I want to be somewhere on a cloud with him, No one else is needed, Our voices create the music within a simple melody, The methodical rhythm of our hearts are one, My, oh my, I wish the sun would come out and play, But then again, I wouldn't be able to have him all to myself, Like I have today, I want to be wrapped up in his arms, Feeling the beat of his heart, Listening to the rhythm is creates and just pray that mines is on the same page, How we love to watch the trees sway side to side, While watching the rain pour, Standing out on the porch with the screen door closed, It's the simple things with us, Hmmm, It's something special about being with the one we care for when it rains, Something about being home in the warm, Being wrapped up in all that love and peace, Sincerity, tranquility, feeling the heat of your heartbeats burning together, On a plane where no one understands the silent language you speak, And you just smile and look at each other deep in the eyes, Hypnotized, because for a change someone understands you for you, The rain is just a piece of what you like to share, I want to be in the room where he is, In the bed where he lays, Wrapped up in his arms all day, Like today would be the perfect day, The rain is flowing and it's getting dark, We could just talk and explore each other's minds, I want to be there with him, I want to be there.... THORNNE.E. XAIVIANTT SACRIFICE I'm willing to give my all surrender my everything can you see it in my eyes? Can you catch my tears on your shoulder as my soul weeps and cries? I would give you the shirt off my back in the midst of winter's worst storm love resinating from my heart I lay next to you keeping us warm Don't worry about paying me back this not a loan. I knew I loved you from day one There you were standing in front of me My gender opposite Yet and still my only clone My friend forever my shadow in the sun's light An embrace for the ages music to my mind's ear Blinded by a love so rare as you hold me standing there I receive your welcome in amazement Standing there unafraid absolutely no fear I'm just glad you are here my dear This feeling is far from great wonderful or nice To know what you endured To see the fight you put up just for me Oh what a sacrifice Starting over and walking this path together The rainbow beams through fog a sign of beauty I knew when I heard you speak for the first time You already knew me Taking a chance Withstanding this hell this punishment The good the bad the uncertain How bad do we really want it? Oh what a sacrifice To say we made it through The ultimate test through time I vouched for you my friend Going the distance Never stop loving you From now until forever Our struggle has reached its end Oh what a sacrifice THE TRANCE Mezmorized by those hips and thighs When you passed by I realized It was your swagg I was paralyzed Your lips your hair I couldn't help but stare My happiness turned to tears Yes I cried I knew I had found love Not just on the outside But an unspoken bond Full of majestic pride Plainly seen in your beautiful eyes Confidence in those diva strides I was on board ready for the ride A feeling I never denied Proud to say I love you Walking hand and hand Side by side As our favorite song plays I treasure these days I look at you May I have this dance? A moment to remember Caught up in this trance TIFFANY CHRISTINA LEWIS Spring Break He inpressed them. As he hovered nearby, the three young ladies ate him with their eyes. His smile shined as he spoke to his friends happily. The ladies knew he had intellect, now they wanted to know what his anatomy would bring. They watched impatiently from their pool chairs, laughing quietly among themselves. They swatted at each other playfully as he began to uncover his skin. As he peeled off his shirt, abs of steel came from their hiding place. His sweat pants removed revealed... his swim trunks, but below them were legs rippling with muscles. He is perfect, they thought as he dove into the pool and swam away. Thank God for Spring Break. URBAN POET DIARY OF A WOMAN (WRITTEN BY A MAN) In my life How many times I been cut with a knife? Raped of my innocence By my uncle At the age of ten At the age of fifteen Raped again Father beating My mother My brother Born stillborn Father cheating with a newborn Twenty one years old Leaving my fam To start another fam Multifam Loyal to one fam Mine the sacrificial lamb Been done wrong Never seen right Mother had no fight Heart attack Heart delayed Or Heart betrayed Our life played Out like, Shakespeare - Sonnet 30 Life so dirty Took my best friend My last of kin Wanted to end My life Thought about jumping, Through a window pane Now I know why they call it Window pane (pain) Went to college So did pain Received a date rape drug God my anti-drug Kept me sane But life breaking my heart Tearing my soul apart Don't know how long I can hold on Graduated from college Student loan Occupation unknown All alone Looking for my fathers affection Fear rejection So I used no protection One night stand Thought he would take my hand In marriage All I got Was a baby carriage Baby's daddy leaving the fam To start another fam Multifam Loyal to one fam Mine the sacrificial lamb Been done wrong Never seen right Heart betrayed Life replayed Got to break the cycle Got to recycle All the pain Use it to gain An advantage in life Waitress @ night Secretary by day Rarely saw my daughter Gods word my food His tears my water And his gift was time For time Stands the test of time Who can stop time? For time is unrelenting Never bending Never repenting Never compromising I must become as time As it invests in itself Second by second I must invest in myself Opportunity by opportunity Giving my life Immunity From struggle and pain Transforming the game Of life Changing my disposition Preparing me for A Company acquisition Which created, a new position Life experiences Made me hard-working An discipline My persistence Won me promotion After promotion Now CEO Living in 90210 Eating at Mastro Driving a Mercedes Benz SL Skiing in Vale Daughter attending Yale Married to the love of my life Dale (PAUSE TO SEND PRAISES TO GOD BY SPIRITUAL MAIL) As I fly In the company jet I have no regret My hurt My
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0,1,2,..., \nonumber \\ \alpha = + N \;, \qquad \gamma = - p+{1\over 2}\,, \qquad Z_{1} = e^{-ipz} \; F (\lambda,- N \;,-p+{1\over 2}\,;{e^{iz} \over 2 \cos z}). \label{3.35}\end{aligned}$$ In these two cases, we do not have found quantization for $p$, instead we have some quantization rules for $\lambda$. However, quite different quantization rules (as expected) will follow from consideration of the differential equation in $r$-variable. By this reason, these cases 1 and 2 will not be considered in the following. $$\begin{aligned} \underline{\mbox{Variant }\; 3,} \qquad A = {p+1 \over 2} \;, \qquad C = {p \over 2} \;, \qquad A+C = p +1/2\;, \qquad A- C =1/2 \;, \nonumber \\ \beta = - N \; \; \Longrightarrow \;\; \underline{\mbox{spectrum}} \qquad p =+\sqrt{\epsilon^{2}- M^{2}} = \lambda - (N +1/2 ) \;, \qquad N = 0,1,2,..., N_{max} \nonumber \\ \alpha = \lambda+p+{1\over 2} \;, \qquad \gamma = p+{3\over2} \;,\; Z_{1} = {e^{iz/2} \over ( \cos z ) ^{p+1/2} } \; F (\lambda+p+{1\over 2}, \; - N, \;p+{3\over2} ; \; {e^{iz} \over 2 \cos z}) \;. \label{3.33}\end{aligned}$$ $$\begin{aligned} \underline{\mbox{ Variant } \; 4}, \qquad A = -{p \over 2} \;, \qquad C = {1 - p \over 2} \;, \qquad A+C = -p +1/2 \;, \;\; A - C = -1/2 \;, \nonumber \\ \alpha = - N \;, \qquad \Longrightarrow \qquad \underline{\mbox{spectrum}} \qquad p = \sqrt{\epsilon^{2} - M^{2}} = \lambda + (N + 1/2) \;, \nonumber \\ \beta = - \lambda - p + {1\over 2} \;, \; \gamma = -p + {1\over 2}\,, \; Z_{1} = {e^{-iz/2} \over (\cos z )^{-p +1/2} } \; F (\lambda-p+{1\over 2},- N \;, -p+{1\over 2}\,;{e^{iz} \over 2 \cos z}) \;. \label{3.36}\end{aligned}$$ To the cases 3 and 4 there correspond different energy spectra: $$\begin{aligned} 3\;, \qquad p =+\sqrt{\epsilon^{2}-m^{2}} = \lambda - (N +1/2 ) \; ; \nonumber \\ 4 \;, \qquad p =+\sqrt{\epsilon^{2}-m^{2}} = \lambda + (N +1/2 ) \;. \label{3.37}\end{aligned}$$ [**4. Solution of the equations in $r$-variable**]{} From eqs. (\[3.24\]) it follows a second-order differential equation for $R_{1}$ (for brevity let $eB$ be noted as $B$) $$\begin{aligned} {d^{2}R_{1}\over dr^{2}}+\left[{m\,\cos r-B\,(\cos r-1)\over \sin^{2} r }-{[m+B\,(\cos r-1)]^{2}\over \sin^{2} r }+\lambda^{2}\right]R_{1}=0\,. \label{3.35}\end{aligned}$$ With a new variable $ y= (1+ \cos r )/ 2 $, eq. (\[3.35\]) reads $$\begin{aligned} y(1-y){d^{2}R_{1}\over dy^{2}}+\left({1\over 2}-y\right){dR_{1}\over dy}- \nonumber \\ -\left[-\lambda^{2}+{m^{2}\over 4} \left({1\over y}+{1\over 1-y}\right)+{m\over 4} \left({1\over y}-{1\over 1-y}\right)-{mB \over y}-B^{2} \left(1-{1\over y}\right)-{B\over 2y}\right]R_{1}=0\,. \label{3.35}\end{aligned}$$ With the substitution $ R_{1} = y^{A} (1-y)^{C} R (y)$, we get $$\begin{aligned} y(1-y){d^{2}R\over dy^{2}}+ \left [ 2A + {1\over 2}-(2A+2C +1)\; y \right] \,{dR\over dy}+ \nonumber \\ +\left [ { A^{2}-A/2-m^{2}/4-m/4+ mB - B^{2}+B/2\over y}+\right. \nonumber \\ \left.+{C^{2}-C/2- m^{2}/4 + m/4\over 1-y} -(A+C)^{2}+\lambda^{2}+B^{2}\right] R=0\,. \nonumber\end{aligned}$$ Requiring $$\begin{aligned} A= {2B - m\over 2}\;,\; {-2B + m +1 \over 2} \,, \qquad C = {m\over 2},\; {1 -m \over 2} \,, \label{3.37} \end{aligned}$$ we arrive at a differential equation of hypergeometric type $$\begin{aligned} y(1-y){d^{2}R\over dy^{2}}+ \left [ 2A + {1\over 2}-(2A+2C +1)\; y \right] \,{dR\over dy} -\left[ (A+C)^{2}-\lambda^{2}-B^{2}\right]R=0\,. \label{3.38}\end{aligned}$$ where $$\begin{aligned} \alpha = A+C - \sqrt{B^{2}+\lambda^{2}}\;, \qquad \beta = A+C +\sqrt{B^{2}+\lambda^{2}} \;, \qquad \gamma = 2A\,+\,{1\over 2} \;, \nonumber \\ R_{1} = ( 1 + \cos r) ^{A} \; (1 - \cos r)^{C} \; F(\alpha, \beta, \gamma ;\; {1 + \cos r \over 2} ) \;. \label{3.39} \end{aligned}$$ In order to have a finite solution at the origin $r=0$ (that corresponds to the half-curve $u_{0} = + \cos z, \; u_{3} = \sin z , u_{1}=0, u_{2}=0$) and at $r = \pi$ (that corresponds to the other part of the curve, $ u_{0} = - \cos z , u_{3} = \sin z , u_{1}=0, u_{2}=0$ ), we must take positive values for $A$ and $C$: $$\begin{aligned} R_{1} = ( 1 + \cos r) ^{A} \; (1 - \cos r)^{C} \; F(\alpha, \beta, \gamma ;\; {1 + \cos r \over 2} ) \;, \qquad A > 0 \;, \; \; C > 0 \;. \label{3.41}\end{aligned}$$ Let us consider all the four variants (for definiteness let us assume that $B>0$ ): $$\begin{aligned} \mbox{Variant } \; 1\;, \qquad \qquad C = {m \over 2} > 0, \qquad A = {2B - m \over 2} > 0 \;,\qquad C+A = + B \;. \nonumber \\ \mbox{Variant } \; 2 \;, \qquad C = {m \over 2} > 0, \qquad A = { m +1 - 2B \over 2} > 0 \;, \qquad C+A = -B + m + {1 \over
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skate at three ISU Championships – 1997 Europeans in Paris, 1997 Junior Worlds in Seoul, and 1998 Junior Worlds in Saint John, New Brunswick. Fivian was coached by Karlheinz Zitterbart and belonged to Eislauf-Club Thun. After retiring from competition, she performed in ice shows and then became a police officer. Programs Competitive highlights JGP: Junior Series (Junior Grand Prix) References Category:1981 births Category:Swiss female single skaters Category:Living people Category:People from Thun Category:Place of birth missing (living people)Q: What are the differences between transfer learning and meta learning? What are the differences between meta-learning and transfer learning? I have read 2 articles on Quora and TowardDataScience. Meta learning is a part of machine learning theory in which some algorithms are applied on meta data about the case to improve a machine learning process. The meta data includes properties about the algorithm used, learning task itself etc. Using the meta data, one can make a better decision of chosen learning algorithm(s) to solve the problem more efficiently. and Transfer learning aims at improving the process of learning new tasks using the experience gained by solving predecessor problems which are somewhat similar. In practice, most of the time, machine learning models are designed to accomplish a single task. However, as humans, we make use of our past experience for not only repeating the same task in the future but learning completely new tasks, too. That is, if the new problem that we try to solve is similar to a few of our past experiences, it becomes easier for us. Thus, for the purpose of using the same learning approach in Machine Learning, transfer learning comprises methods to transfer past experience of one or more source tasks and makes use of it to boost learning in a related target task. The comparisons still confuse me as both seem to share a lot of similarities in terms of reusability. Meta-learning is said to be "model agnostic", yet it uses metadata (hyperparameters or weights) from previously learned tasks. It goes the same with transfer learning, as it may reuse partially a trained network to solve related tasks. I understand that there is a lot more to discuss, but, broadly speaking, I do not see so much difference between the two. People also use terms like "meta-transfer learning", which makes me think both types of learning have a strong connection with each other. I also found a similar question, but the answers seem not to agree with each other. For example, some may say that multi-task learning is a sub-category of transfer learning, others may not think so. A: Meta-learning is more about speeding up and optimizing hyperparameters for networks that are not trained at all, whereas transfer learning uses a net that has already been trained for some task and reusing part or all of that network to train on a new task which is relatively similar. So, although they can both be used from task to task to a certain degree, they are completely different from one another in practice and application, one tries to optimize configurations for a model and the other simply reuses an already optimized model, or part of it at least. A: First of all, I would like to say that it is possible that these terms are used inconsistently, given that at least transfer learning, AFAIK, is a relatively new expression, so, the general trick is to take terminology, notation and definitions with a grain of salt. However, in this case, although it may sound confusing to you, all of the current descriptions on this page (in your question and the other answers) don't seem inconsistent with my knowledge. In fact, I think I had already roughly read some of the cited research papers (e.g. the MAML paper). Roughly speaking, although you can have formal definitions (e.g. the one in the MAML paper and also described in this answer), which may not be completely consistent across sources, meta-learning is about learning to learn or learning something that you usually don't directly learn (e.g. the hyperparameters), where learning is roughly a synonym for optimization. In fact, the meaning of the word "meta" in meta-learning is denoting something of a higher or second-order kind For example, in the context of training a neural network, you want to find a neural network that approximates a certain function (which is represented by the dataset). To do that, usually, you manually specify the optimizer, its parameters (e.g. the learning rate), the number of layers, etc. So, in this usual case, you will train a network (learn), but you will not know that the hyperparameters that you set are the most appropriate ones. So, in this case, training the neural network is the task of "learning". If you also want to learn the hyperparameters, then you will, in this sense, learn how to learn. The concept of meta-learning is also common in reinforcement learning. For example, in the paper Metacontrol for Adaptive Imagination-Based Optimization, they even formalize the concept of a meta-Markov decision process. If you read the paper, which I did a long time ago, you will understand that they are talking about a higher-order MDP. To conclude, in the context of machine learning, meta-learning usually refers to learning something that you usually don't learn in the standard problem or, as the definition of meta above suggests, to perform "higher-order" learning. Transfer learning is often used as a synonym for fine-tuning, although that's not always the case. For example, in this TensorFlow tutorial, transfer learning is used to refer to the scenario where you freeze (i.e. make the parameters non-trainable) the convolution layers of a model $M$ pre-trained on a dataset $A$, replace the pre-trained dense layers of model $M$ on dataset $A$ with new dense layers for the new tasks/dataset $B$, then retrain the new model, by adjusting the parameters of this new dense layer, on the new dataset $B$. There are also papers that differentiate the two (although I don't remember which ones now). If you use transfer learning as a synonym for fine-tuning, then, roughly speaking, transfer learning is to use a pre-trained model and then slightly retrain it (e.g. with a smaller learning rate) on a new but related task (to the task the pre-trained model was originally trained for), but you don't necessarily freeze any layers. So, in this case, fine-tuning (or transfer learning) means to tune the pre-trained model to the new dataset (or task). How is transfer learning (as fine-tuning) and meta-learning different? Meta-learning is, in a way, about fine-tuning, but not exactly in the sense of transfer learning, but in the sense of hyperparameter optimization. Remember that I said that meta-learning can be about learning the parameters that you usually don't learn, i.e. the hyper-parameters? When you perform hyper-parameters optimization, people sometimes refer to it as fine-tuning. So, meta-learning is a way of performing hyperparameter optimization and thus fine-tuning, but not in the sense of transfer learning, which can be roughly thought of as retraining a pre-trained model but on a different task with a different dataset (with e.g. a smaller learning rate). To conclude, take terminology, notation, and definitions with a grain of salt, even the ones in this answer. Aspirin impairs antioxidant system and causes peroxidation in human erythrocytes and guinea pig myocardial tissue. This study aims to investigate possible effects of aspirin treatment on cellular oxidant/antioxidant system. In the first part of the study, 15 guinea pigs were given aspirin at three different doses (2200, 440 and 10 mg/kg/day) for 30 days and five were fed on the same diet without aspirin. After a month, animals were killed and their hearts were removed for use in analyses. In the other part, after fasting blood samples were obtained from 11 volunteer subjects, they were given aspirin (approximately 10 mg/kg/day) for 30 days and second blood samples were obtained after 1 month. Five volunteer subjects also participated as placebo control. Oxidant/antioxidant parameters, namely superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT), malondialdehyde (MDA), nonenzymatic superoxide scavenger activity (NSSA), susceptibility to oxidation (SO) and antioxidant potential (AOP) values, were assayed in the samples. Antioxidant system was found to be impaired in the heart tissue from guinea pigs and in the erythrocytes from volunteer subjects. AOP and NSSA values were lower and MDA higher after aspirin treatment in both heart tissues and erythrocytes. In guinea pig heart tissue, SO was lower, but GSH-Px and CAT were unchanged after aspirin treatment. In human erythrocytes, SO was unchanged, but GSH-Px and CAT activities were increased after aspirin treatment. Changes in guinea pig heart tissues from animals treated with higher aspirin doses were more drastic relative to those of human erythrocytes, but no meaningful differences were observed between analysis parameters of control and lower-dose (10 mg/kg/day) aspirin-treated animals. Our results suggest that high-dose aspirin exerts significant toxicity to guinea
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for unnecessarily prolonging the war. The discontent was spreading rapidly as morale continued to plummet. By some accounts, the Kaiser was with some troops near his train that Monday when he heard a sudden burst of fire from not far away. Glancing up, he was just in time to see a squadron of enemy bombers swooping overhead, aiming for his train. He kept his composure, as did his soldiers, but some nearby civilians scattered, among them a panic-stricken chef in hat and apron who ran for cover as the bombers attacked. Three bombs whistled through the air and exploded harmlessly nearby. They were followed by a shower of propaganda leaflets which fluttered to earth as the aircraft disappeared. The soldiers laughed as the cook sheepishly picked himself up. The Kaiser laughed too. 'Idiots!' he said, looking at the civilians. A bombing raid was no reason to panic. Nevertheless, it might be a good idea to arm the train with machine guns, if it was going to be a target for enemy aircraft from now on. The Kaiser made a note to have it done as soon as he got back to Spa. In Paris, the leaders of the Allied nations were meeting to discuss an end to the war. In a house on the rue de l'Université, British prime minister David Lloyd George and his counterparts from France and Italy were debating the terms for an Armistice with Marshal Ferdinand Foch and General Sir Henry Wilson. The subject had occupied them for weeks, but it had taken on a new urgency that morning with the news of the British breakthrough around Valenciennes. The politicians were meeting to finalise the precise wording of the terms that would be offered to the Germans if they decided to seek an Armistice in the next few days. The house on the rue de l'Université was the Paris residence of Colonel Edward House, President Woodrow Wilson's personal representative at the talks. The United States considered itself an associate of Britain, France and Italy, rather than a formal ally, but with a large army in the field it nevertheless had a big say in the talks. Indeed, the peace proposals to be put to Germany were based on a fourteen-point plan outlined to Congress by President Wilson the previous January. The mood was ebullient as the leaders talked. Turkey had stopped fighting since Lloyd George had been in Paris. So had Austria-Hungary, Germany's last remaining ally in the field. The Germans were on their own now, with no one to help them. They still had an army in France and Belgium, but they would surely accept an Armistice within a few days if one was offered to them. The Allied ministers had been working for a long time to get the terms of an Armistice exactly right. Too lenient, and the Germans would resume the war at a later date. Too harsh, and they might refuse to sign at all. The terms the Allies had eventually decided on were harsh in the extreme, stripping the Germans of arms and territory and leaving them unable to defend themselves against any future aggression. The terms were so stringent that Lloyd George feared the Germans might well refuse to sign. He had said as much to Marshal Foch, who had agreed with him that the Germans probably wouldn't sign. But Foch wasn't worried, because the German army was beaten in the field, so whether they signed or not made little difference in the long run. The fighting would be over by Christmas, whether the Germans liked it or not. The meeting began at 11 o'clock and was over by lunchtime. It was agreed that President Wilson would make the approach to the Germans, telling them to contact Marshal Foch if they wanted to learn the Allies' terms for an Armistice. Lloyd George took his leave of Georges Clemenceau and the Italian premier Vittorio Orlando as soon as the discussion was over and set off back to England after a highly satisfactory few days in France. His party travelled by train to Boulogne, where a British destroyer was waiting to take them to Dover. There was no longer much danger from U-boats, but the crossing was rough, even by Channel standards. Sir Maurice Hankey, secretary to the War Cabinet, was seasick during the voyage, as were most of the others. The sea was so bad that they had to be taken off by boat when they reached Dover. Nevertheless, Lloyd George was in a splendid mood as they travelled through the night to London. The collapse of Austria and Turkey meant that he was bringing wonderful news home with him. He was going to see the king the next day to brief him on the Paris talks. In the afternoon, he would announce the terms of the Austrian Armistice in the House of Commons. Another few days and he would surely announce the Armistice with Germany as well. After that, he could call a general election and go to the country on his war record. The Allied politicians were all agreed on an Armistice, but for General John Pershing, commanding the United States troops on the Western Front, the issue was far from clear-cut. Why, he wondered, did they want an Armistice with the Germans when the British, French and Americans were within a few days of defeating them once and for all? Why not just keep going until the German army had collapsed altogether and they had no choice but to surrender? It made little sense to stop now, just when they had the Germans on the run. Years ago, as a cadet at West Point, Pershing had witnessed the funeral train of Ulysses S. Grant, the Civil War general who had later become US president. The general had been nicknamed 'Unconditional Surrender' Grant for his refusal to accept anything less from the defeated South. He had known what he was doing, in Pershing's opinion. The Confederates had understood that they were beaten after Grant had finished with them. The Germans needed to understand, too, if the Allies wanted to avoid having to fight the whole war again some day. 'There can be no conclusion to this war until Germany is brought to her knees,' Pershing had recently told his army. He believed it passionately. If there was an Armistice, both sides would simply stop fighting and go home. The Germans would hold their heads high, declaring that they had never been defeated in the field. But if they were forced to surrender, they would have to lay down their arms in front of their conquerors. The Allies would proceed to Berlin and march down Unter den Linden with their bands playing and their flags flying. A victory parade in Berlin was the only way to show the Germans that they had been vanquished. Anything less was folly. Pershing had made his views known in a paper to the Supreme War Council, only to have them rejected out of hand. 'Political, not military', had been Lloyd George's judgement. 'A clear announcement of his intention to become a candidate for the presidency', had been Colonel House's. The politicians took it for granted that Pershing had ulterior motives in advocating unconditional surrender rather than an Armistice. They presumed that he wanted to ride down Unter den Linden at the head of his men so as to become an American hero, ideally placed to seek the presidency in 1920. They didn't believe him when he insisted that his motives were purely military. Marshal Foch understood what Pershing was saying, but did not share his concern. 'Tell General Pershing not to worry,' he had announced reassuringly. 'I'm going to get exactly what he wants from the Germans.' In Foch's view, the Armistice terms were so stiff that they amounted to a surrender in all but name and couldn't be interpreted by the Germans as anything else. But Pershing was not so sure. Defeat in the field was the only language the Germans understood. The Allies were making a big mistake in seeking an Armistice instead of carrying on the war to the bitter end. As he travelled to the Second Army's headquarters in the Argonne for a flying visit to discuss the continuing advance, Pershing couldn't help wondering if they wouldn't all come to regret the decision one day. At Escarmain, four miles across the fields from Le Quesnoy, the French had put a stuffed fighting cock on a pole at the crossroads. The cock was France's national emblem, a symbol of their resurgence over the retreating Germans. It had amused Private Stephen Graham of the 2nd battalion, Scots Guards as he marched past it at dawn, on his way up to the line. He thought it a bizarre sight in the middle of a war, with bagpipes playing and gunfire booming in the distance as the New Zealanders began their assault on Le Quesnoy. The Scots Guards were part of that morning's advance, but they were not due to go into action until the next day. While the New Zealanders were busy at Le Quesnoy, the Scots were bypassing the citadel on their way to Villers-Pol, their starting point for the attack next morning. It had been misty when they set out, but the weather soon cleared as the sun rose. Before long, they made their first halt, falling out for a cigarette beside the Sepmeries road while batteries of sixty-pounders and eight-inch howitzers bombarded the Germans from a position just behind them. The gunners obligingly warned the troops to 'hold tight' when they were about to fire. Most of the men kept their fingers in their ears as the bombardment continued. They weren't sorry when the halt was over and they resumed their march towards the front. They soon had their first glimpse of the enemy, as Graham later remembered: '
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* on productivity (Tilman *et al*. [1997](#ele13167-bib-0056){ref-type="ref"}; Hector *et al*. [1999](#ele13167-bib-0026){ref-type="ref"}) are also much needed to validate the results of theory and numerical experiments. Authorship {#ele13167-sec-0014} ========== BC and SLS designed the study. BC wrote the model codes, ran the simulations, and wrote the first draft of the manuscript. All authors discussed the results and contributed to revisions. Conflict of Interest {#ele13167-sec-0015} ==================== The authors declare that they have no conflict of interest. Supporting information ====================== ######   ###### Click here for additional data file. We thank S. Vallina, C. García‐Comas, and three anonymous reviewers for useful comments that had tremendously improved earlier versions of the manuscript. This study was supported by CREST (P.I. SLS; grant number JPMJCR12A3) funded by the Japan Science and Technology (JST) Agency, by a Grants‐in‐Aid for Scientific Research (KAKENHI) (grant number JP16K21701; P.I. BC) funded by Japan Society for the Promotion of Science (JSPS), by the Helmholtz Society via the program PACES, and by the German Research Foundation (DFG) within the Priority Program DYNATRAIT (P.I. KW). Data Accessibility Statement {#ele13167-sec-0016} ============================ The model and observational data are archived in <https://github.com/BingzhangChen/ROMS-NPZDcont.git> (<https://doi.org/10.5281/zenodo.1410803>). Differential atrophy of sensory and motor fibers following section of cat peripheral nerves. Differential effects of peripheral nerve section on myelinated sensory and motor fiber populations were investigated in 5 hindlimb nerves of cats. Upon electrical stimulation of each nerve, monophasic compound action potentials were recorded from the L6, L7 and S1 dorsal and ventral roots, and the impedance of each root was measured. The decline in the electrical charge computed from potentials 43 to 252 days after nerve section gave a measure of the effect of axotomy on the diameters of sensory and of motor fibers in each nerve. No significant difference in the rate of atrophy of sensory and motor fibers was observed after about 45 days following nerve section. After about 145 and 245 days, however, dorsal root charge contributions had decreased significantly more than ventral root values. Exponential decay curves were fitted separately to charge data for sensory and for motor fibers. The calculated value for the endpoint of the decay was about 35% of the control value for motor fibers, and not significantly different from zero to sensory fibers. These results suggest that in response to axotomy, myelinated motor fiber diameters decline at first but later stabilize, while myelinated sensory fibers continue to decline and may atrophy completely if regeneration is prevented. Possible roles of electrical activity and of 'trophic' interactions with the periphery in the maintenance of cell properties are discussed.<?php namespace Ivoz\Cgr\Domain\Model\TpCdr; use Ivoz\Core\Domain\Model\EntityInterface; interface TpCdrInterface extends EntityInterface { public function getDuration(); /** * @return array|null */ public function getCostDetailsFirstTimespan(); /** * @return \DateTime | null */ public function getStartTime(); /** * @return string */ public function getRatingPlanTag(): string; /** * @return string */ public function getMatchedDestinationTag(): string; /** * Get cgrid * * @return string */ public function getCgrid(): string; /** * Get runId * * @return string */ public function getRunId(): string; /** * Get originHost * * @return string */ public function getOriginHost(): string; /** * Get source * * @return string */ public function getSource(): string; /** * Get originId * * @return string */ public function getOriginId(): string; /** * Get tor * * @return string */ public function getTor(): string; /** * Get requestType * * @return string */ public function getRequestType(): string; /** * Get tenant * * @return string */ public function getTenant(): string; /** * Get category * * @return string */ public function getCategory(): string; /** * Get account * * @return string */ public function getAccount(): string; /** * Get subject * * @return string */ public function getSubject(): string; /** * Get destination * * @return string */ public function getDestination(): string; /** * Get setupTime * * @return \DateTime */ public function getSetupTime(): \DateTime; /** * Get answerTime * * @return \DateTime */ public function getAnswerTime(): \DateTime; /** * Get usage * * @return integer */ public function getUsage(): int; /** * Get extraFields * * @return string */ public function getExtraFields(): string; /** * Get costSource * * @return string */ public function getCostSource(): string; /** * Get cost * * @return float */ public function getCost(): float; /** * Get costDetails * * @return array */ public function getCostDetails(): array; /** * Get extraInfo * * @return string */ public function getExtraInfo(): string; /** * Get createdAt * * @return \DateTime | null */ public function getCreatedAt(); /** * Get updatedAt * * @return \DateTime | null */ public function getUpdatedAt(); /** * Get deletedAt * * @return \DateTime | null */ public function getDeletedAt(); /** * @return bool */ public function isInitialized(): bool; } Activity and expression of ecto-5'-nucleotidase/CD73 are increased during phenotype conversion of a hepatic stellate cell line. Hepatic stellate cells (HSC) play a crucial role in the development of liver fibrosis and are important targets in liver disease therapy. Adenosine acts as an extracellular signaling molecule in various tissues and in liver this nucleoside exerts protective effects. Ecto-5'-nucleotidase/CD73 is a marker for the plasma membrane and is considered to be a key enzyme in the generation of adenosine in the extracellular medium, by transforming AMP into adenosine. In addition, adenosine production from AMP is also catalyzed by alkaline phosphatase. We compared the extracellular metabolism of AMP and transcriptional levels of the ecto-5'-nucleotidase/CD73 and tissue non-specific alkaline phosphatase (TNALP) in activated and quiescent HSC of the mouse hepatic stellate cell line GRX. This cell line expresses a myofibroblast phenotype in basal medium and both retinol and indomethacin treatment induced a phenotypic change of GRX cells to quiescent HSC. Ecto-5'-nucleotidase activity and its mRNA expression were found to be higher in quiescent HSC than in activated HSC. During phenotype conversion, mediated by retinol, the AMP decay was accelerated with adenosine accumulation in extracellular medium, likely due to the decrease in adenosine deaminase activity also observed in quiescent HSC. The treatment with retinol also involves transcriptional activation of TNALP. Taken together, these data suggest that ecto-5'-nucleotidase-dependent adenosine generation may play a role in the regulation of quiescent HSC functions.Red Flag This Post Please let us know here why this post is inappropriate. Here is some background: The code resides in the worksheet object and not a VBA module.The "named ranges" (i.e. I'm still getting a compile error. I have it as: Public Sub FunctionNotValidVarType() MsgBox "VarType " & VarType & " is not supported. Compile Error Label Not Defined Vba Access I would still be interested to know where I am going wrong with my labelling if anyone can spot the error. In this respect we can say that Visible and IsNull(EmployeeNumber) vary directly with each other so the evaluation of one IS the
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クセス制御について](../../security-center/security-center-just-in-time.md) **Azure Security Center の監視**: はい **責任**: Customer ### <a name="15-record-network-packets"></a>1.5:ネットワーク パケットを記録する **ガイダンス**: Azure Virtual Machines のフロー レコードを生成するために、NSG フロー ログをストレージ アカウントに記録できます。 異常なアクティビティを調査するときに、Network Watcher パケット キャプチャを有効にして、通常とは異なる異常なアクティビティがないかネットワーク トラフィックを確認できるようにすることができます。 * [NSG フロー ログを有効にする方法](../../network-watcher/network-watcher-nsg-flow-logging-portal.md) * [Network Watcher を有効にする方法](../../network-watcher/network-watcher-create.md) **Azure Security Center の監視**: はい **責任**: Customer ### <a name="16-deploy-network-based-intrusion-detectionintrusion-prevention-systems-idsips"></a>1.6:ネットワーク ベースの侵入検出または侵入防止システム (IDS または IPS) をデプロイする **ガイダンス**: Network Watcher によって提供されるパケット キャプチャとオープン ソースの IDS ツールを組み合わせることにより、広範囲の脅威に対するネットワーク侵入検出を実行できます。 また、必要に応じて Virtual Network セグメントで Azure Firewall をデプロイして、脅威インテリジェンスを有効にし、悪意のあるネットワーク トラフィックに対して [警告して拒否] を構成することもできます。 * [Network Watcher とオープン ソース ツールを使用してネットワーク侵入検出を実行する](../../network-watcher/network-watcher-intrusion-detection-open-source-tools.md) * [Azure Firewall をデプロイする方法l](../../firewall/tutorial-firewall-deploy-portal.md) * [Azure Firewall でアラートを構成する方法](../../firewall/threat-intel.md) **Azure Security Center の監視**: はい **責任**: Customer ### <a name="17-manage-traffic-to-web-applications"></a>1.7:Web アプリケーションへのトラフィックを管理する **ガイダンス**: 信頼された証明書に対して HTTPS/SSL が有効になった Web アプリケーションのために Azure Application Gateway をデプロイできます。 Azure Application Gateway では、ポートにリスナーを割り当て、規則を作成し、Linux 仮想マシンなどのバックエンド プールにリソースを追加することによって、アプリケーション Web トラフィックを特定のリソースに転送します。 * [Application Gateway をデプロイする方法](../../application-gateway/quick-create-portal.md) * [HTTPS を使用するように Application Gateway を構成する方法](../../application-gateway/create-ssl-portal.md) * [Azure Web アプリケーション ゲートウェイを使用したレイヤー 7 負荷分散について](../../application-gateway/overview.md) **Azure Security Center の監視**: 利用不可 **責任**: Customer ### <a name="18-minimize-complexity-and-administrative-overhead-of-network-security-rules"></a>1.8:ネットワーク セキュリティ規則の複雑さと管理オーバーヘッドを最小限に抑える **ガイダンス**:Azure 仮想マシンで構成されているネットワーク セキュリティ グループまたは Azure Firewall でのネットワーク アクセス制御を定義するには、Virtual Network サービス タグを使用します。 セキュリティ規則を作成するときは、特定の IP アドレスの代わりにサービス タグを使うことができます。 規則の適切なソースまたは宛先フィールドにサービス タグ名 (ApiManagement など) を指定することにより、対応するサービスのトラフィックを許可または拒否できます。 サービス タグに含まれるアドレス プレフィックスの管理は Microsoft が行い、アドレスが変化するとサービス タグは自動的に更新されます。 * [サービス タグとその使用方法の概要](../../virtual-network/service-tags-overview.md) **Azure Security Center の監視**: 利用不可 **責任**: Customer ### <a name="19-maintain-standard-security-configurations-for-network-devices"></a>1.9:ネットワーク デバイスの標準的なセキュリティ構成を維持する **ガイダンス**: Azure Policy を使用して、Azure Virtual Machines (VM) の標準的なセキュリティ構成を定義して実装します。 また、Azure Blueprints を使用して、Azure Resource Manager テンプレート、ロールの割り当て、Azure Policy 割り当てなどの主要な環境成果物を単一のブループリント定義にパッケージ化することにより、大規模な Azure VM デプロイを簡略化することもできます。 このブループリントをサブスクリプションに適用し、ブループリントのバージョン管理によるリソース管理を有効にすることができます。 * [Azure Policy を構成して管理する方法](../../governance/policy/tutorials/create-and-manage.md) * [ネットワークに関する Azure Policy のサンプル](/azure/governance/policy/samples/#network) * [Azure Blueprint を作成する方法](../../governance/blueprints/create-blueprint-portal.md) **Azure Security Center の監視**: 適用外 **責任**: Customer ### <a name="110-document-traffic-configuration-rules"></a>1.10:トラフィック構成規則を文書化する **ガイダンス**: Azure 仮想マシンで構成されているネットワーク セキュリティやトラフィック フローに関連する NSG やその他のリソースのタグを使用できます。 個
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a copy of the License at http://www.apache.org/licenses/LICENSE-2.0 Unless required by applicable law or agreed to in writing, software distributed under the License is distributed on an "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the License for the specific language governing permissions and limitations under the License. */ package v1 import ( "encoding/json" "reflect" "testing" jsoniter "github.com/json-iterator/go" ) type GroupVersionHolder struct { GV GroupVersion `json:"val"` } func TestGroupVersionUnmarshalJSON(t *testing.T) { cases := []struct { input []byte expect GroupVersion }{ {[]byte(`{"val": "v1"}`), GroupVersion{"", "v1"}}, {[]byte(`{"val": "extensions/v1beta1"}`), GroupVersion{"extensions", "v1beta1"}}, } for _, c := range cases { var result GroupVersionHolder // test golang lib's JSON codec if err := json.Unmarshal([]byte(c.input), &result); err!= nil { t.Errorf("JSON codec failed to unmarshal input '%v': %v", c.input, err) } if!reflect.DeepEqual(result.GV, c.expect) { t.Errorf("JSON codec failed to unmarshal input '%s': expected %+v, got %+v", c.input, c.expect, result.GV) } // test the json-iterator codec if err := jsoniter.ConfigFastest.Unmarshal(c.input, &result); err!= nil { t.Errorf("json-iterator codec failed to unmarshal input '%v': %v", c.input, err) } if!reflect.DeepEqual(result.GV, c.expect) { t.Errorf("json-iterator codec failed to unmarshal input '%s': expected %+v, got %+v", c.input, c.expect, result.GV) } } } func TestGroupVersionMarshalJSON(t *testing.T) { cases := []struct { input GroupVersion expect []byte }{ {GroupVersion{"", "v1"}, []byte(`{"val":"v1"}`)}, {GroupVersion{"extensions", "v1beta1"}, []byte(`{"val":"extensions/v1beta1"}`)}, } for _, c := range cases { input := GroupVersionHolder{c.input} result, err := json.Marshal(&input) if err!= nil { t.Errorf("Failed to marshal input '%v': %v", input, err) } if!reflect.DeepEqual(result, c.expect) { t.Errorf("Failed to marshal input '%+v': expected: %s, got: %s", input, c.expect, result) } } } Author Comments Reviews Rated 4.5 / 5 stars2015-06-28 19:12:27 It's great that you did a tribute to your favorite game! I wish I was more familiar with the characters. I don't have to be to realize how creative this is! This giant cat thing seriously looks amazing. I love his expression too. It's great to see him drinking from all those bottles at once. I guess drawings of bars are appealing to me. It just seems like something so real. With these characters, it's anything but. I even like the little bottles in the background. Everything should be detailed. Rated 5 / 5 stars2014-10-13 17:02:15 Rated 4 / 5 stars2013-10-05 05:04:08 Heard of the game, never played it, but this is one amazing artwork. Unique characters; an apparently everyday situation where the strangeness of it all contrasts with the... apparently normal situation. Great work on coloring and detail too.INTRODUCTION ============ Microorganisms are a major concern in both clinical infections and food contamination and are a threat to public health, necessitating accurate and rapid identification of isolates to the species level for quick and successful treatment to improve patient care ([@b1-jmbe-19-76]--[@b3-jmbe-19-76]). Matrix-assisted laser desorption ionization--time of flight mass spectrometry (MALDI-TOF MS) and 16S rRNA gene sequencing are the most commonly used methods for identifying unknown microorganisms in clinical, food, and environmental samples ([@b4-jmbe-19-76]--[@b10-jmbe-19-76]), a crucial prerequisite for quick and accurate intervention. These modern technologies are quicker and more accurate than conventional methods for microbial identification, such as plating on differential agar or other phenotypic-based assays including the API-20E and MB-12E systems ([@b7-jmbe-19-76], [@b11-jmbe-19-76], [@b12-jmbe-19-76]). A major obstacle to bringing these modern technologies into the undergraduate teaching laboratory is the up-front cost of purchasing the specialized equipment and software, as well as the need for access to computer and database facilities and skilled personnel to operate the equipment and software. These challenges can prevent undergraduate educators from exposing those modern technologies to a large number of inexperienced students in teaching laboratories. Furthermore, in developing countries, costs may limit access to this equipment, which may not be available in all areas ([@b13-jmbe-19-76]). Where modern technologies are unavailable, microbiologists in clinical and veterinary diagnostic laboratories and in food industries have to rely on conventional methods and commercial biochemical identification kits to identify bacteria from clinical and environmental sources for disease control and treatment ([@b3-jmbe-19-76], [@b11-jmbe-19-76], [@b14-jmbe-19-76]). To overcome the challenges of using modern technologies, we used the Oxoid MICROBACT GNB 12A biochemical identification kit with colored liquids instead of live organisms in our undergraduate teaching laboratory to identify four unknown oxidase-negative and gram-negative rods isolated from four different hypothetical clinical cases. The commercially available MICROBACT GNB 12A, 12E, 12B and 24E kits are used in clinical and routine diagnostic laboratories for the identification of Enterobacteriaceae and other gram-negative bacteria from clinical and other sources ([@b14-jmbe-19-76]--[@b17-jmbe-19-76]). In recent years, a combination of gene sequencing and biochemical test results precisely identified organisms used in the construction of databases for MALDI-TOF MS ([@b18-jmbe-19-76]). Thus, teaching these phenotypic-based assays to undergraduate students, so that they may identify unknown organisms to the species level using biochemical tests, comprises an important intellectual pillar of the microbiology course. The MICROBACT kit employs a simple procedure with visible color reactions and provides reliable results ([@b12-jmbe-19-76], [@b19-jmbe-19-76]--[@b21-jmbe-19-76]); however, when this assay is performed by inexperienced undergraduates, there is an unacceptable rate of misleading biochemical reactions due to bubble creation, cross-contamination from adjacent wells during inoculation, and improper sealing of the strips leading to evaporation of the inoculum. Additionally, the light weight and slim design of the strip makes it easy to mishandle and knock over, leading to contamination of the bench and incubation baskets with live organisms. Finally, two consecutive days are required to complete each of the tests and to obtain accurate results, which can be problematic for scheduling of undergraduate teaching laboratories within a large teaching university delivering a number of science courses. These factors in combination can lead to difficulty in accurate identification of the microorganism, which can ultimately lead to discouragement and disengagement of the students with this exercise. We have designed a simulated MICROBACT strip assay in a single lab that overcomes the problems associated with using live microorganisms and provides second-year biomedical science students with an accurate, visual learning experience that conveys the basic concept of the MICROBACT assay and the use of phenotypic assays to correctly identify unknown bacterial isolates. We used non-toxic and affordable artificial colors ([Table 1, Appendix 1](#sup1){ref-type="supplementary-material"}) to simulate the effects of actual microorganisms on a MICROBACT 12A identification strip. Use of artificially colored liquids removed the potential hazard of using real organisms, allowing effective facilitation of student's learning in a very safe and economical way, with minimal laboratory skills and reduced instructor intervention. Students record the results from the simulated MICROBACT strip of unknown bacterial isolates ([Fig. 1](#f1-jmbe-19-76){ref-type="fig"}) and discuss the results within groups, which creates a collaborative learning environment in the classroom to reinforce students' learning. ![Results of simulated MICROBACT strip assay for four sample unknowns: gram-negative bacteria (B, C, D, and E) and an un-inoculated control strip.](jmbe-19-76f1){#f1-jmbe-19-76} This simulated MICROBACT strip assay can easily be incorporated in other
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drivers isn’t just about raising much-needed revenue to help fund transit: It’s also about shifting behavior. Because the forces that keep drivers in their cars are formidable. To be fair, Baker does sometimes talk in terms of moving people, rather than cars, which is exactly the right way to look at it. And obviously, it’s not practical for him to take the T every day, or even frequently. But his dismissiveness does signal something: that Baker, at heart, remains as mired in car culture as the rest of us. Globe columnist Yvonne Abraham can be reached at [email protected] and on Twitter @GlobeAbrahamcarlaypage Follow along: Our Imagery We have an extensive archive of Tuft & Needle visual content available for usage with our written permission. If you would like access to use any of the imagery or have any questions about how to use the content, please visit our Pressroom.Browse by Tags The United Way of Southwestern Indiana maintains a very valuable " Community Resource Guide " on their website. This guide lists services and programs offered by hundreds of nonprofit agencies around southwestern Indiana, from tutoring (for...2. Understanding PART of the Above Graphic — and Yes, This WILL Hurt Let’s start at the bottom left, the one legal entity with which you’re already familiar: The City of Anaheim, which is governed by its City Council. All of the other yellow ovals in the graphic are different organizations that are, essentially, “The City of Anaheim” wearing different hats. Putting on one of these different hats is supposed to give the City Council different superpowers that it doesn’t normally enjoy. The first of these magic hats to be created was the Anaheim Redevelopment Agency (“ARA”) — an example of a Redevelopment Agency (“RDA”) in the graphic above. (I’ll explain what a “Successor Agency” is below.) Redevelopment Agencies were supposed to direct state money towards areas of greatest need within a community; through some mysterious process they ended up making cronies of City Council members wealthy and not doing a whole lot to help the poor. (More on that latter.) The City and the ARA were able to use a law called the “Joint Exercise of Power Act” (“JEPA” in the above graphic) to enter into a Joint Powers Agreement (“JPA”) to create a new organization called a “Joint Powers Authority” (“JPA” in the graphic) some special powers differing from either the City and the ARA. (You may note that the acronym “JPA” is used twice; once for a new legal entity and once for the agreement, authorized by the JEPA, that creates that entity. This is unfortunate, but you can usually tell which someone is talking about by context. OJB apologizes if all of this is killing you.) The JPA (“Authority”) that was created by the JPA (“Agreement”) between the City of Anaheim and the ARA was called the Anaheim Public Financing Agency (“APFA”). Again, the RDA and the APFA were designed to be governed by the same people, just wearing different hats. The APFA has had the ability to, among other things, issue municipal bonds for big projects that big donors want. The whole idea of allowing a City to create a JPA with, essentially, itself was to give the City Council the ability to do things like issue those bonds without a public vote — that is, a vote by the people who will be on the hook to repay them — that the City Council cannot do while wearing its own hat. This arrangement was peculiar and ill-advised — but in the late ’90s the Supreme Court of California held it was not illegal. (Whether that has changed given the elimination of Redevelopment is one of the issues in the lawsuit.) Because that’s not enough — and because it was concerned that it might lose a lawsuit against CATER and IOC (described below) — Anaheim has also set up a separate JPA with the Anaheim Housing Authority (“AHA”), creating a new entity called the Anaheim Housing and Public Investment Authority (“AHPIA”). On the chart above, “AHA” has the same status to enter into a JPA with the City as a Redevelopment Agency had had, while AHPIA is another example of a JPA created by such an agreement. And, again, the ARA, SA, APFA, AHA, and AHPIA are all governed by the members of the City Council, wearing different hats. (OJB apologizes if it is hurting your head. It did not come up with this sort of scheme; it is just reporting the news. Don’t worry — this section is about to get more interesting.) The new wrinkle here is this: Due to rampant corruption deployed by special interests that wanted to tap into these huge pots of money, Redevelopment Agencies were scuttled beginning in 2011. Then-newly elected Governor Brown got the legislature to eliminate the system of Redevelopment Agencies (“RDA” in in the graphic above) and replace them with Successor Agencies (“SA” in the graphic above.) Successor Agencies did not have the ability to create new projects, such as issuing new bonds, but solely to “wind down” the activities of the Redevelopment Agencies. A Successor Agency was also just the City Council wearing a different hat. One power it retained was that it would now become the counterparty to the City in the JPA (Agreement) governing the JPA (Authority) after the RDAs were eliminated. Why did Redevelopment Agencies get eliminated by Governor Jerry Brown, with an uneasily unified Democratic Party joined by some honorable anti-Redevelopment Republicans such as Chris Norby? It’s because there was a tendency for municipal (i.e., city, county, special agency) governments to abuse Redevelopment funds. So many people stood to make so much money by arranging approval of lucrative projects that it was corrupting municipal governments. Those interests could spend so much money not only to lobby candidates, but to make independent expenditures on campaigns to elect candidates who wouldn’t even need to be lobbied, but would just do as they were told — that serving the greater public good just went out of the window. And so Governor Brown pulled the plug — which Anaheim wants to stick back into its socket. Just in case that this is news to anyone: Lots of people stand to make a lot of money on these major public construction projects if they go through. For really big projects — such as the proposed expansion of the Anaheim Convention Center, which led to the lawsuit discussed here — the two primary winners are (1) Wall Street investment bankers, such as Citigroup, whose clients just live for this sort of huge sale of tax-free municipal bonds, and (2) the construction company (in this case Turner Constructors) who got the (no-bid, of course) contract to build it. (Major construction projects in Anaheim tend to be divided up between Turner and Clark Construction, whose name you may have seen on the $200 million ARTIC rail terminal on the 57 between the Honda Center and Angels Stadium.) Other people stand to make money as well. Any middlemen involved in creating the deal — and especially in steering it through the passages of the City government — get a healthy cut. The middleman in this case is apparently Curt Pringle’s group, Pringle and Associates — who either directly or with the Anaheim Chamber of Commerce or by some other path funds and populates Anaheim Blog, managed by Matt Cunningham and reportedly directed by Pringle and Associates’ VP and chief lobbyist, Todd Priest. Anaheim Blog, largely led by what is believed to be Priest himself writing as “Anaheim Insider,” which takes regular potshots at both CATER — the Coalition of Anaheim Taxpayers for Economic Responsibility, of which your humble author is General Counsel which will feature prominently in the next installment of this series — and Orange Juice Blog and Anaheim Mayor Tom Tait. (Those three entities are far more different than the City Council and its different personae; CATER’s Board and Staff — the latter being me — literally does not talk to the Mayor about litigation matters other than in open sessions of the City Council.) Construction unions also want to see the Convention Center expanded, because that creates jobs, and even when I have challenged them to their faces they have literally refused to apply any sort of cost-benefit principles to their analysis. “How many jobs must a half billion dollar commitment of public funds create for it to be worthwhile?”, I have asked (probably not using those exact terms). “This project CREATES JOBS!“, is the (non-)answer. In my experience, the service unions are a little more sophisticated, because after the Building Trades workers are gone they are the ones who will be working in the expanded Convention Center — or not, if it turns out to be a bad economic bet. And the public employee unions have to be even more sophisticated than that — because if the City commits too much money to too many projects that bring too little money into the City — convention centers are generally understood to be loss-leaders — then public employees are going to be cut (and possibly, depending on how the law looks in the decades ahead, pension obligations as well. The recent Stockton Bankruptcy decision gives real cause for concern on that point.) So the policy concern is: “This project may DESTROY JOBS
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Eternity will only be sent the absolutely oldest trees root bark! The Highest Environmental Ethical standards- Also of utmost important to us at Eternity is the fact that our Acacia is harvested Responsibly and Ethically in Hawaii. Lateral side-roots are harvested from trees ranging from 25-80+ years old (almost all of the trees we receive bark from are close to the 80 year mark!), the harvesting of Lateral side roots minimizes the stress to the trees being harvested from. Many other supplier harvest haphazardly, ripping trees from the ground in a quest to procure a maximum amount of root bark. We are honored to work with a supplier who holds the integrity necessary to harvest in harmony, and this is a big part of what makes are Acacia root bark so vibrationally profound! We love nature and respect the spirit of life, all of our plants are harvested with the most sincere adherence to environmental harmony standards! Freshness is Crucial- Unlike many of our competitors, we opt to order in small batches regularly in order to ensure that all of our Acacia root bark is as absolutely fresh as possible! Our shipments are intended to only last us about 1-2 weeks in our store. Many other shops offering Acacia confusa purchase very large shipments in order to get the lowest possible rate from their suppliers, while this might be economically practical it does compromise the quality! Having extremely fresh root bark is crucial to maximizing the aromatic potency, which is why we always buy in small batches 🙂 ************* ****Very Exciting News…..Our prices for 2k, 3k, 5k and 10k have significantly lowered! These quantities sell very regularly, but we are dropping the prices as a thanks to all of our wonderful customers 🙂 Enjoy some Acacia now at an even better price!**** This Acacia Confusa Root Bark is the same source and same harvest technique as our very popular Large Shredded material. The only difference is that after drying this material is put through a shredder to strip the bark down to about 1/10th its size. The picture above shows the finer material, some pieces are a half inch or so with our finely shredded acacia as well. If you’d prefer large or even smaller specimen please come check out our other Acacia listings. We are carrying this to meet customer demand for more easily incense burnable root bark. Our Large Shreds are very beautiful, but their density makes it quite difficult to burn them as incense…this bark is more frayed and less thick by piece, so it is ideal for burning as incense! Harvested within a month, the freshest and finest quality Acacia Confusa Root Bark available. Don’t be fooled by others trying to pass trunk bark as root bark, this is the real deal root Bark material and our sales volume and return customer satisfaction speaks to the quality. ************* Eternity in a Box is proud to be able to offer to our customers, top quality and freshly harvested Hawaiian Acacia Confusa Root Bark! As show in the picture above, our root bark is shredded rather than powdered to maintain aromatic potency. Our Acacia is harvested responsibly and ethically in Hawaii. Lateral side-roots are harvested from trees ranging from 25-80+ years old. This minimizes the stress to the trees being harvested from. Acacia Confusa is sometimes referred to as the ‘Rainbow Tree’ or the ‘Thinking of Each-Other Tree’ in Taiwan where they grow naturally. Good vibes huh? 🙂 These trees are originally native to Taiwan, though were brought to the Pacific region years ago. They grow vigorously in Hawaii and are even considered of a higher medicinal value than the Taiwanese native trees. Acacia Confusa has been used in traditional Taiwanese medicine to help heal blood disorders as well as for detoxification. The more mystical application involves preparation into an Ayahuasca-like brew, and has been utilized for visionary and spiritual purposes. This plant is sometimes chewed by natives or even smoked to produce psychedelic states. This plant is unique in that it is sometimes brewed without any MAOI containing plants when used for shamanic visioning. Whereas, the South American traditional ayahuasca brew involves the combination of tryptamine rich leaves (Chacruna) with Caapi vine which contain betacarboline compounds. The psychopharmacological reasoning is not well understood as to why the tryptamines are active without the use of MAOI plants in conjunction. The tannins and pigments can be used as a natural dye as well, making this plant very versatile. We sell this herb for ceremonial use as an incense or to be meditated with, NOT FOR HUMAN CONSUMPTION! The Tryptamine profile in this plant is not to be taken lightly, KEEP OUT OF REACH OF CHILDREN AND PETS! I have yet to listen to what the root of this plant has to say, but the trunk speaks clearly. it seems to be intimidating at first but its a misunderstanding it truly has a beautiful voice once youve given it time to finish its thoughts.The immigrant caravan, now up to 11,000 people, is approaching the Texas borders with Mexico. We need to send President Trump a message: Don’t Let Them In! If they are admitted, they get all kinds of statutory protections.Q: How to enforce usage of the @Override annotation? Is there a static analysis tool that can enforce usage of the @Override annotation consistently that can be run outside of an IDE? CheckStyle has a MissingOverride check but it only applies to methods that use the @inheritDoc Javadoc tag. I'm looking for a tool that can be run in a new build configuration on a continuous integration machine. A: PMD now has a MissingOverride rule. What about PMD or Findbugs? PMD enables that you can even write your own rule (if it isn't disposable in the default rule set). https://pmd.github.io/pmd-6.3.0/pmd_userdocs_extending_writing_pmd_rules.html A: One way is to use TeamCity's "Inspection" runner. I'm not sure if it really qualifies as running outside the IDE since it's configured in IntelliJ and it works by running IntelliJ in headless mode on the TeamCity side. Facebook and Messenger platforms to integrate BTS-themed stickers After Coca-Cola, Facebook has joined the K-pop bandwagon by partnering with the popular record-breaking boyband BTS and LINE FRIENDS. The social media giant announced that it will integrate the BT21 stickers into its Facebook and Messenger platforms from July 19. In October 2017, the K-pop group BTS collaborated with LINE FRIENDS and created BT21, which is basically a collection of frames, AR filters and stickers. Each of the BTS members has designed their own LINE characters following the characteristics such as values, taste and personality. The latest announcement on Facebook has created a lot of excitement among the BTS fans and a lot of netizens have claimed that they would reactivate their old Facebook accounts to enjoy using the upcoming stickers. Many of the fans have also said that they would use the stickers while chatting with people on Messenger. Jennifer Whitley, creative director for Messenger art, told Adweek that the creative expression plays a big role in communicating with people on Messenger. According to her, the platform aims to offer more fun ways that would help the users to express themselves better using various stickers depicting different experiences. LINE FRIENDS released the BT21 line of characters as the first output of their "FRIENDS CREATORS" project. It collaborates with global artists to create a new intellectual property. On July 11, the Incheon International Airport in South Korea announced that they will employ BTS-designed BT21 characters at the airport. They will feature the collection to promote the airport and provide "entertaining and interactive facilities and services" to the customers. The airport has decided to air eight promotional films featuring BT21. The list of films will be revealed on the official social media platform of the airport. According to the report, the luggage carts will also feature the BT21 characters. "85 per cent of travellers to Korea are from Asia, 60 per cent of whom are millennials. This project reflects the need for a marketing strategy targeting (the younger age group)," Chung Il-young, the president and CEO of Incheon International Airport told Asia One. Incheon International Airport authority said that the latest joint project with BTS will surely act as "a historic collaboration with the very best names in the world."GENOME ANNOUNCEMENT {#s0} =================== Species of the *Capnocytophaga* genus are commensal organisms that are most commonly found as naturally occurring microbiota in human, dog, and cat oral cavities ([@B1][@B2][@B3]). Six of the nine recognized species are associated with periodontal disease in humans ([@B1], [@B4][@B5][@B7]). *C. canis*, *C. canimorsus*, and *C. cynodegmi* are opportunistic zoonotic pathogens that inhabit the oral cavities of cats (*Felis catus*) and dogs (*Canis familiaris*) ([@B8], [@B9]). Severe complications from cat and dog bite wound infections in humans can include sepsis, meningitis, and endocarditis, which are often fatal to immunocompromised
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years ago, said speakers at an Oct. 2 news conference at the memorial dedicated to the civil rights figure in Washington. Bishop George V. Murry of Youngstown, Ohio, chair of the U.S. bishops’ Ad Hoc Committee Against Racism, is seen near the Martin Luther King Jr. Memorial in Washington Oct. 2. He and other faith leaders gathered near the monument to commemorate Rev. King’s 1957 essay about “Nonviolence and Racial Justice.” (CNS photo/Tyler Orsburn) That the news conference was scheduled in advance of, and held the day after, the Las Vegas shooting spree that killed 58 people and injured more than 500 only underscored the importance of Rev. King’s message, according to the speakers. “It’s hard to find something in times like these that doesn’t sound like clichés,” said Bishop George V. Murry of Youngstown, Ohio, chairman of the U.S. bishops’ Ad Hoc Committee Against Racism. “As a society, we need to stop making excuses and commit to nonviolence.” He added, “Pope Francis speaks of the earth as our common home. So it is. And so it is with our society. … It is so easy to speak of human dignity,” said, “but do we believe it selectively — applying it to some people but not to others?” Bishop Murry, who is African-American, acknowledged he has been the target of racism and segregation. One of the more frustrating episodes for him, he told Catholic News Service, was when a white airline passenger called for a flight attendant because he did not want to sit next to Bishop Murry. Rev. King’s essay, “Nonviolence and Racial Justice,” appeared in the Feb. 6, 1957, issue of the Christian Century, a theological journal. It laid out his principles for acting nonviolently to seek change. In his essay, Rev. King wrote: “How is the struggle against the forces of injustice to be waged? There are two possible answers. One is resort to the all too prevalent method of physical violence and corroding hatred. The danger of this method is its futility. Violence solves no social problems; it merely creates new and more complicated ones. Through the vistas of time a voice still cries to every potential Peter, ‘Put up your sword!’ The shores of history are white with the bleached bones of nations and communities that failed to follow this command.” One of the points Rev. King made about nonviolent resistance as an alternative is that it “does not seek to defeat or humiliate the opponent, but to win his friendship and understanding.” “The nonviolent resister,” he said, “must often express his protest through noncooperation or boycotts, but he realizes that noncooperation and boycotts are not ends themselves; they are merely means to awaken a sense of moral shame in the opponent. The end is redemption and reconciliation. The aftermath of nonviolence is the creation of the beloved community, while the aftermath of violence is tragic bitterness.” “Things looked bleak, and the violence was real, but Rev. King held that high ground. And people rallied to him,” said Carl Anderson, supreme knight of the Knights of Columbus, which sponsored the news conference. “He understood that there were two non-negotiable principles in our democracy: first, that all are created equal and are entitled to the equal protection of our nation’s laws; second, that in our democracy, there can be no place for political violence.” The United States has many challenges, including renewed racism by groups like the Ku Klux Klan, he said, noting that from its founding in 1882, the Knights as an organization “has long assisted the cause of racial equality.” Anderson added, “Today, as then, we stand united in the principle that all are created equal, and we reiterate the words of Pope Francis last month calling for ‘the rejection of all violence in political life.’ We believe the way of nonviolence is as relevant today as ever.” “Dr. King is still the beacon of the way forward,” said Bishop Charles E. Blake Sr., presiding bishop of the Church of God in Christ, in remarks delivered by Bishop Edwin C. Bass, president of the denomination’s Urban Initiatives. Bishop Blake added that 2018, the 50th anniversary of Rev. King’s assassination, should be seen as “the year of Martin Luther King Jr.,” with programs and conferences to renew the commitment to nonviolence. The Rev. Eugene Rivers, founder and director of the Boston-based W.J. Seymour Institute for Black Church and Policy Studies, called this moment “a biblical opportunity to be salt and light in the midst of this political darkness. … We have to learn how to disagree without being disagreeable.” Rev. Rivers cautioned the change would not be instantaneous: “I’m not optimistic, yes, but I’m full of faith.”A badass fight in a women's prison, another in a hotel room, sex, threats and exploding cows. Fanshees will see all that and more in the second episode of the new season of "Banshee," airing at 9 p.m. Jan. 17 on Cinemax. "I think Episode 2—like if you want someone to understand what 'Banshee' is—that is a great episode because it is a full menu of everything you can get on our show," said exec producer Greg Yaitanes, who also directed the episode. Two of the wildest scenes involve the exploding cows you can see in the preview above. The feud between Banshee's resident crime lord Kai Proctor (Ulrich Thomsen) and Kinaho Tribal Chief Alex Longshadow (Anthony Ruivivar) heats up when Longshadow decides to blow up some cows at Proctor's stockyard. I won't spoil Proctor's retaliation against Longshadow that comes later in the episode, but what he does is so utterly Proctor—and so "Banshee"—I was giggling with joy when I watched it. During a recent phone chat, Yaitanes talked about how the production enjoys the extremes, but only if the crazy ideas make sense within the framework of the story. "We are fearless in going there. Like if we want to do it or we think it serves the show, then we go for it and don't hold back in the course of it," he said, chuckling a little. "If we're gonna blow up a cow then we're gonna like have cow parts raining down on them and... you get excited for how that pays off and you don't see it coming." Episode 2 also reinforces another hallmark of "Banshee": Yaitanes and exec producer/writer Jonathan Tropper don't go easy on the female characters. Explaining that the female cast members throw themselves into the fights "even harder than the guys," Yaitanes said, "We are an equal opportunity fight show." In Episode 2, stars Ivana Milicevic and Trieste Kelly Dunn are both swept up by what Yaitanes calls "the Lucas Hood effect." As you can see in the two other previews below, Carrie Hopewell (Milicevic) is sentenced to prison for shooting up Rabbit's hole last season and Deputy Siobhan Kelly (Dunn) has to deal with the return of her abusive ex to Banshee. Both women square off against different foes in separate fights that Yaitanes and Co. edit together in what could be called an operatic, epic scene if it weren't so brutal. Yaitanes said the two fights were conceived, choreographed and filmed separately, but with an eye to mashing them together in the editing room to create "this great Russ Meyer throwback in some ways." Meyer directed the cult classic "Faster Pussycat, Kill! Kill!" "Oh my God, I love that scene," Yaitanes said. "It's like everything you want to have happen. Everything you want to have happen in Episode 2 happens." The Chicago Cubs on Tuesday sought City Hall permission to expand construction hours at Wrigley Field, with bleacher work falling well behind schedule on the team's $375 million ballpark renovation project. On Wednesday night, TBS will air a special episode of "Conan" filmed entirely in Cuba, making it the first American late-night show to broadcast from the island nation since the embargo went into effect in 1962. Host Conan O'Brien will follow in the footsteps of Jack Paar,... "Star Wars Rebels" continues to offer up gifts for the fans. On Monday's first-season finale, it reintroduced the beloved character Ahsoka Tano from "The Clone Wars" animated series. Now it's recruiting a former vampire slayer.Friedrich Ritter von Friedländer-Malheim Friedrich Friedländer, later Friedrich Ritter von Friedländer-Malheim (Mahlheim) (January 10, 1825 – June 13, 1901), was a Bohemian-Austrian painter. Friedländer was born in Kohljanowitz/Uhlířské Janovice, Bohemia. He studied at the Vienna Academy, and later under Professor Waldmüller, and visited Italy in 1850, Düsseldorf in 1852, and finally Paris. He is associated with the Düsseldorf school of painting. He devoted himself at first to historical pictures, creating a genuine sensation with his painting entitled "The Death of Tasso". After 1854 he painted genre pictures exclusively,
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And I’m guessing if you’re here reading this you feel a similar calling to be the best version of yourself. I choose this path when I was about 8 years old. I remember sitting outside on the grass at yoga camp, indian style, starring at the man dressed in white teaching us how to drink water from our nose (a yogic technique to cleanse your nasal passages.) Staring at him because he had a glow that was undeniable and indescribable. All I could feel was happiness exuding from him. It was like being in his presence made me happier. I called him Guru. This man had meditated for close to 20 years in the Himalayan Mountains of India. When he would talk about enlightenment, happiness, the limitless capabilities of ourselves, the words, no matter how unbelievable, would land on my ears and hit my heart as truth. The reason I’m going on and on about this experience is… Because that’s what happiness can look like (not that my path or your path has to look like his), not someone randomly saying, “I’m really happy!” when you ask how they are. That happiness lasts for moments. Most of us have a range of emotions in every moment of every day. I mean I can go from…. Waking up excited and happy because it’s a brand new day and the sun is shining to sad and crying because I look over and see a picture of my parents and brother and I miss seeing them, to checking my email and getting angry because something happened in my business that shouldn’t have, to disappointed because I wanted to talk to a friend about something and she doesn’t pick up the phone, And this can happen all within a 15 minute time period! It’s a roller coaster ride of emotions. It is LIFE. Truth is I’ve learned that my life is way more enjoyable and exciting when I’m embracing all of those emotions within myself, not just happiness. Getting into a space of allowing all of our emotions (including the “negative” ones) actually allows for a deeper connection with the right person versus showing up as perfect all the time. So, when someone simply doles out the advice that when you’re happy you can find happiness with someone else – it’s true AND it doesn’t mean you have to be perfect to fall in love and meet the person you’re meant to spend your journey with. Tell me in the comments below, how does it feel for you when someone tells you this, do you think you need to be perfect to find love?Q: How to detect akka actor termination is due to system shutdown and avoid restarting it I have a Spring application that makes use of a small Akka actor system (using Java), where I have a MasterActor that extends Akka's AbstractActor that initialises a Router and sets up a few worker actors. It also watches the lifecycle of the workers. I want to restart a Worker actor if it happens to die because of some Exception. public MasterActor(ActorPropsFactory actorPropsFactory) { this.actorPropsFactory = actorPropsFactory; int workers = Runtime.getRuntime().availableProcessors() - 1; List<Routee> routees = Stream.generate(this::createActorRefRoutee).limit(workers).collect(Collectors.toList()); this.router = new Router(new ConsistentHashingRoutingLogic(getContext().system()), routees); } private ActorRefRoutee createActorRefRoutee() { ActorRef worker = getContext().actorOf(actorPropsFactory.create(getWorkerActorClass())); getContext().watch(worker); return new ActorRefRoutee(worker); } private void route(Object message, Supplier<String> routingKeySupplier) { String routingKey = routingKeySupplier.get(); RouterEnvelope envelope = new ConsistentHashingRouter.ConsistentHashableEnvelope(message, routingKey); router.route(envelope, getSender()); } @Override public Receive createReceive() { return receiveBuilder() .match( EventMessage.class, message -> this.route(message, () -> message.getEvent().getId().toString())) .match( Terminated.class, message -> { logger.info("WorkerActor {} terminated, restarting", message.getActor()); // todo: detect whether the system is shutting down before restarting the actor router = router.removeRoutee(message.actor()) .addRoutee(createActorRefRoutee()); }) .build(); } The problem I am having is that if the Spring Application fails to start up. (For example it fails to connect to the database, or some credentials are incorrect or something), I am receiving the Terminated message from all workers, and the Master actor tries to start new ones, which also get Terminated immediately, going into an endless loop. What is the correct way to detect such scenario? Is there a way for the Master actor detect that the actor system is shutting down so that the workers are not restarted again? A: Can't you just set up a supervision strategy for your Router so you can inspect the type of Exception that causes the failure? This way you also don't need to restart your workers manually. EDIT: You set up SupervisorStrategy like this: private static SupervisorStrategy strategy= new OneForOneStrategy( 10, Duration.ofMinutes(1), DeciderBuilder.match(ArithmeticException.class,e->SupervisorStrategy.resume()) .match(NullPointerException.class,e->SupervisorStrategy.restart()) .match(IllegalArgumentException.class,e->SupervisorStrategy.stop()) .matchAny(o->SupervisorStrategy.escalate()) .build()); final ActorRef router= system.actorOf( new RoundRobinPool(5).withSupervisorStrategy(strategy).props(Props.create(Echo.class))); You can read more about it here: Router Actor supervision Fault tolerance in Akka Mohamed Jameel Ahmed For others named Muhammad Ahmed, see the Muhammad Ahmed navigation page Mohamed Jameel Ahmed (; born 13 October 1969) is a Maldivian lawyer and politician who was the fourth Vice President of the Maldives from 2013 to 2015. He previously served as Minister of Justice from July 2005 to August 2007, as Minister of Civil Aviation and Communication from November 2008 to May 2009 and as Minister of Home Affairs from February 2012 to May 2013. He was once a member of the New Maldives group. In 2015, he was impeached by the parliament and removed from office. Political career In July 2007, Jameel made history when he defied conservative Islamists and nominated three women judges, the first time the Maldives had admitted women to the judicial bench. He resigned as Minister of Justice after accusing President Maumoon Abdul Gayoom of failing to take action against rising Islamic militancy and blocking progress of reforms. One month after Jameel resigned, the Maldives experienced its first ever homegrown terrorism incident when young Islamic radicals blew up a homemade bomb in a public park, injuring a dozen foreign tourists. Jameel is renowned for his public speaking talents and passion for the reform of the criminal justice system, Jameel secured the highest number of votes in the elections to the Party Executive Council, polling even more votes than President Gayoom. After leaving government, Jameel became a co-founder of the New Maldives which lead the Opposition against the incumbent 30-year-old regime. After the election of President Mohamed Nasheed, Jameel served as Minister of Civil Aviation and Telecommunications from November 12, 2008 to May 30, 2009. Jameel was impeached following a no confidence motion submitted by the ruling party, backed by the opposition and independent parliament members. According to sources, the main reason for impeachment was for the illegal attempt of a coup to takeover Presidency. These dealings were leaked by the Parliamentarians, primarily for the reason that all political stakeholders in the country strongly opposes coup. References Category:1969 births Category:Living people Category:Maldivian lawyers Category:Vice Presidents of the Maldives Category:Government ministers of the MaldivesAye Myint Kyu Brigadier General Aye Myint Kyu (, ; born 21 December 1947) was the Minister of Culture of Myanmar (Burma) and a former deputy minister of Ministry of Hotels and Tourism. He successfully organized the 27th SEA Games opening and closing ceremony as the chairman of the Preparation Committee for the opening and closing ceremony of the 27th SEA Games and showed the Myanmar Culture to the world. Biography Aye Myint Kyu was born in Minhla, Bago Division, the son of Thi Han and Kyi Kyi. His wife is Khin Swe Myint. He received a Bachelor of Science degree from Defence Services Academy in 1968. References Category:1947 births Category:Burm
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announced the release of his second album. The album is titled ‘Here Comes the Weekend’ and has 14 brand new songs that were written over the past 6 months. It is available to download on Apple Music and other major music retailers worldwide. Mike retired from the U.S. Navy after 35 years of service in December, 2015. He had also previously served in the military for 20 years as a Chief and an Officer, now he lives in Thailand close to the beach and continues to travel and write more songs. Tennessee Country Singer Songwriter, Mike Contoni has announced the release of his second album. The album is titled ‘Here Comes the Weekend’ and has 14 brand new songs that were written over the past 6 months. It is available to download on Apple Music and other major music retailers worldwide.Mike retired from the U.S. Navy after 35 years of service in December, 2015. He had also previously served in the military for 20 years as a Chief and an Officer, now he lives in Thailand close to the beach and continues to travel and write more songs. Download Here Comes The Weekend on Apple Music: https://itunes.apple.com/us/album/here-comes-the-weekend/id1142753095 Mike Contoni's Websites: https://www.reverbnation.com/mikecontoni https://twitter.com/contonimike https://www.facebook.com/mikecontoni1 Genre: Download Here Comes The Weekend on Apple Music:Mike Contoni's Websites:Genre: Country Music ### ### 30 -0 9 -2016 15 : 0 7 GMT AMYCANBE ALBUM IN STORES NOW Italian Alternative Rock Quartet, Amycanbe's latest release, an 11 track album featuring their best works to date is now available to download on Bandcamp and other major music retailers worldwide. Originally released on Soundcloud in April, 2015 by The Cervia based band is also gearing up for a string of upcoming live dates due to be announced soon. Originally released on Soundcloud in April, 2015 by Open Productions, it has received raving reviews by Independent and Mainstream music critics worldwide and has been received well by both their loyal fans and new fans across many genres. The band's unique, uplifting sound makes every one of their releases ever so special for fans and this album is bound to be one of their most successful to date.The Cervia based band is also gearing up for a string of upcoming live dates due to be announced soon. Download Wolf: https://amycanbe1.bandcamp.com/album/wolf Band Members: Francesca Amati - Lead Singer Marco Trinchillo Download Wolf:Marco Trinchillo Mattia Mercuriali Alternative Rock ### ###ecreasing order. 11, 3/47, -0.1, -2/11, -0.5 Sort -757, -2, 0, 5, -3 in decreasing order. 5, 0, -2, -3, -757 Sort 2/23, -34, 12 in descending order. 12, 2/23, -34 Sort -3, 8, -638, -2 in descending order. 8, -2, -3, -638 Put -28686, -3, -5, 2 in decreasing order. 2, -3, -5, -28686 Sort 0, -3, 1725, 11 in descending order. 1725, 11, 0, -3 Put -31, 7, -22, 4, 0 in decreasing order. 7, 4, 0, -22, -31 Put -17, -5.85, -3 in decreasing order. -3, -5.85, -17 Put -1/5, 21, 4 in ascending order. -1/5, 4, 21 Put -5, -531, 0, 1, -33 in decreasing order. 1, 0, -5, -33, -531 Put 546, -4, -2, 4, 1, 0 in increasing order. -4, -2, 0, 1, 4, 546 Sort -1, 22, -462. -462, -1, 22 Sort -6, 2/13, 0.12597, -3, -1/3 in decreasing order. 2/13, 0.12597, -1/3, -3, -6 Sort 73, -2, 8, 2, 0, -4. -4, -2, 0, 2, 8, 73 Sort 2218, 5, -3, -37 in ascending order. -37, -3, 5, 2218 Sort 71, 3, 5, -27, -4, 0 in ascending order. -27, -4, 0, 3, 5, 71 Put -10, 136, -0.17 in descending order. 136, -0.17, -10 Put -19, 0, 4, 24, -800 in decreasing order. 24, 4, 0, -19, -800 Sort -1, 38, 15, 4. -1, 4, 15, 38 Put 2/5, -3/7, -44502 in decreasing order. 2/5, -3/7, -44502 Sort -1, -3, 2, -4033. -4033, -3, -1, 2 Sort 1/162, 0.4, 1.1 in increasing order. 1/162, 0.4, 1.1 Sort -4/1213, 2/3, -3 in increasing order. -3, -4/1213, 2/3 Sort 162, 7, 1, -2/3. -2/3, 1, 7, 162 Put 93, 5, 157 in descending order. 157, 93, 5 Sort 3, 2, 8, 74, 1, -3 in descending order. 74, 8, 3, 2, 1, -3 Put 0.5, 1.5, 2, 1174 in ascending order. 0.5, 1.5, 2, 1174 Sort -12, 4, -3826. -3826, -12, 4 Put -154, 5, 12, -5, 3, 1 in decreasing order. 12, 5, 3, 1, -5, -154 Sort -4, -8, -5, -1807, 11 in decreasing order. 11, -4, -5, -8, -1807 Put -3, -0.122, 2, 17, 1/19 in descending order. 17, 2, 1/19, -0.122, -3 Sort 0.3, 0.52174, 2 in descending order. 2, 0.52174, 0.3 Put 1, -263, 4, -3, 116 in decreasing order. 116, 4, 1, -3, -263 Sort 0.6, 306, 9 in descending order. 306, 9, 0.6 Sort 1/2, 3, 4708. 1/2, 3, 4708 Put -1, -928, -2, 2 in ascending order. -928, -2, -1, 2 Sort 2, -719, 1.1, -0.5. -719, -0.5, 1.1, 2 Put 5, -14, -0.07, -0.7, -2, -3 in descending order. 5, -0.07, -0.7, -2, -3, -14 Sort 3, 1, -56, 328, -2 in decreasing order. 328, 3, 1, -2, -56 Put 0, 1024, -19 in decreasing order. 1024, 0, -19 Sort 3, -5, -68659. -68659, -5, 3 Sort 2, 5, -5, -94, 8 in decreasing order. 8, 5, 2, -5, -94 Put -6, 4, -1082 in descending order. 4, -6, -1082 Put 2360, 3, -51 in decreasing order. 2360, 3, -51 Put 5/9, -2/5, 0.1, 1/54, -1/3 in ascending order. -2/5, -1/3, 1/54, 0.1, 5/9 Put -7, 0.2, -27/37, -11 in ascending order. -11, -7, -27/37, 0.2 Sort -20, 4, -960 in descending order. 4, -20, -960 Sort 0.3, 5, 0.07, 0.15 in descending order. 5, 0.3, 0.15, 0.07 Sort 1/4, -26, 1.053, 0.4 in increasing order. -26, 1/4, 0.4, 1.053 Sort -2, 0, -22, -16, -4 in
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. The local people are wonderful and friendly, the seafood is divine, it’s perfect for swimming, there’s things to do, or you can simply chill out and kick back. Rabbit Island Introduction Rabbit Island is just two square kilometres and apart from some coconut tree lined beaches, it has dense jungle in the interior. It’s size makes it the perfect paradise getaway for more open minded and budget travellers. There’s no traffic on the island (or roads for that matter), just boats ferrying passengers and supplies to and from the mainland. With no rushing around it makes Rabbit Island quite unique, and an ideal place to spend some time going barefoot. With no electricity from dusk till 10.00pm (or sometimes a bit later) or wi-fi, it really is a great place to chill out and get away from it all. If you find it hard to switch off, and get in touch with more rustic living, it may not be the place for you. Boats arriving on the coconut tree lined main beach at Rabbit Island If, however, you want to bask in the warm sea, eat delicious fresh seafood, sway in a hammock and completely switch off, you’ll be in paradise, so read on. How to Get to Rabbit Island (Koh Tonsay) from Kep Kep to Rabbit Island travel by boat Rabbit Island is only 4.5km from Kep and just 20 minutes away by boat. You can arrange a return trip from your hotel in Kep. Tickets cost $7 for a day return, and $10 for a period return if you’re going to stay on the island. Most crossings occur at around 9am, and you’ll see groups of travellers and day-trippers waiting to board boats in the mornings at Kep Pier. Kep Pier is at the eastern side of Kep, near the Independence Monument which is a couple of blocks inland. If you buy a ticket from your hotel (which seems to be the easiest way), you’ll get picked up in a tuk-tuk and taken to the pier. You can also buy tickets at the pier for boat travel to Rabbit Island on the day or in advance. The boat trip to Rabbit Island is a lovely journey, with the island getting increasingly closer and great views backs to the mainland and Kep National Park. More boats leave throughout the day but you’ll may find that it costs more. When you’re on the island you can either use your return ticket, or you can arrange a boat to take you back when you want for just $5 per person. Boats moored up on Rabbit Island which you can take both ways to Kep There’s plenty of boats returning to Kep throughout the day, so if you want to stay a bit longer, it’s cheap and hassle-free to get back to the mainland. Just ensure that arrange your visit back at one of the restaurants where there’s more chance that someone can speak English. Rabbit Island Accommodation Highly recommend staying on Rabbit Island and spending at least one night there. So many people just go for the day and they miss out on a wonderful experience. If you’re travelling, you can easily spend a week there or more, depending on how much you like the quite life. Accommodation is only available in basic, bungalow style huts on wooden stilts, made from bamboo, wood, straw and dried coconut leaves. Bungalows are only available on the main beach that faces Kep and the mainland. There are about seven sets of huts offering basic accommodation on Rabbit Island (Koh Tonsay). From the outside they all look pretty much the same with some a bit bigger than others, however, it’s inside where there are some marked differences. Prices range from $5 (outside shared toilets and shower and some without electric points) to $10 per night (Western style toilet and shower). Expect to pay $7 or $8 for a bungalow with your own shower, electric point and squat toilet. Expect to pay more over Christmas and New Year. Note that electricity only runs from 6pm to 10pm so a torch is handy at night. If you like photography and gadgets, ensure you’ve fully charged up before you come to Rabbit Island. At the time of our visit in February 2013, there was no wi-fi on the island. If you’re always online, take advantage of the break and get immersed in the real world for a few days! It’s not crowded at all on Rabbit Island, however, during high season it’s probably a good idea to book ahead. Also, it gets busier at weekends with Cambodian day-trippers and some who stay on for the weekend. Basic bungalows with hammocks on Rabbit Island, let’s face it what more do you need It’s worth stressing that huts on Rabbit Island are very basic and you’ll be no doubt sharing with some of the local wildlife. If you’re more accustomed to hotel comforts, be warned it’s very rustic on Rabbit Island. If you love nature and swinging around in a hammock (all huts have them) then you’ll be in for a treat. It’s very relaxing listening to the sounds of ocean and birds, and expect to be up early with the locals. If you’re in luck, you may even have a gecko on your roof. At the time of our visit the huts furthest away from the mainland offered the newest huts with Western style toilets. Restaurants and Eating on Rabbit Island Accommodation doubles up as restaurants on Rabbit Island. For the best gourmet experiences, you must eat the yummy and fresh seafood which is cheap and available everywhere. Fish, shrimps, crab and squid are offered on all menus and it is all deliciously fresh, and cooked in a variety of styles. If you love your seafood you’re in for a delight, and it’s much cheaper than what you’ll get in Kep. The Amok is popular and one of the best Khmer dishes available. If you’re familiar with Indian food the Amok is perfect as it’s an Indian style curry with coconut, dry chilli and onion. You can also get dishes with local ‘Kampot Pepper’ which are simply divine. Try the local speciality Kep crab with Kampot pepper, which is simply divine. Western style dishes are also available everywhere for food at any time of day, with breakfasts consisting of muesli, cereals, eggs or omelettes. Things to do on Rabbit Island (Koh Tonsay) Rabbit Island is great for just chilling and relaxing, however, there’s plenty to do if you’re more active inclined. Beaches on Rabbit Island Main beach The main beach on Rabbit Island golden sand and approximately half a kilometere long. It’s the beach that you arrive on Rabbit Island and you can see Kep across to the mainland. The beach is only a few metres wide, however, there’s room for sun loungers, deck chairs and plenty of hammocks on the trees hugging the shoreline. Other beaches on Rabbit Island There’s about half a dozen other beaches on Koh Tonsay which you can find by taking the walk around the island. Like the main beach, they’ve all got golden sand. Generally, they were clean when we were there, however, there was some plastic washed up on the shore. The only way to find them is to either go out and explore the island on foot or if that’s too much like hard work, you can take a boat to visit them. Walking on Rabbit Island There’s a couple of walks that you can do on the island or if you’d sooner take it easy you can stroll up and down the main beach. Round the Island Walk You can take a pleasant walk around the island, which takes about one and a half to two hours. Total distance is just under eight kilometres. If you time it right it’s a straightforward walk around the island, however, if the tide is higher you could end up getting wet and wading part of the way through mangroves. Just over half way round you will come to a beach with a long spit head of sand going out to the sea. It’s a great place to stop for a swim or a paddle. A local family live by the spit head beach and will ferry you back to the main beach for $5 per person. If you’ve got camera equipment you may need to take them up on their offer. If you’re in need of refreshments, they’ll also quite happily sell you a fresh coconut. If you’re feeling just slightly adventurous, however, you’ll get around the island just fine without the aid of a boat. Walk into the interior You can also do a walk into the small interior of the island. It’s quite hilly and you’ll need to take a guide to navigate through the jungle. You’ll be able to hear and see more birds and wildlife when you’re away from the main beach. There’s an old military pill box in the jungle which you can explore. Be careful if you go as apparently there’s lots of snakes inside the old military building (or that’s what the locals told us and they seemed quite adamant). A guide will cost around $5 per person. Swimming on Rabbit Island The main beach is ideal for swimming as the water warm and shallow
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, the ones Bill Gates publicly complains about will be as meaningless as the ones NY State makes my poor ESL students take. Matthew Yglesias wonders whether we're all home run hitters. Some say those who hit more home runs are more valuable, and should get more money, simple as that. Only it's not home runs he's focusing on--it's test scores. For years I've listened to people making such comparisons. They'd fire you in the NFL if you didn't score touchdowns, or whatever guys in the NFL do, so why shouldn't they fire teachers? Oddly, though, the NFL never had to recruit via subway ads, or pay people to take courses, or run various 6-week courses showing you how to be a football player. For most of my career, in fact, the low-paying Board of Education was unable to find enough people to actually do the job. And it wasn't, despite popular sentiment, because the job was too easy. Now, of course, things are different. The economy is in the crapper and our job looks so attractive that virtually every day hedge fund managers, horrified there is still a middle class, vilify us while reveling in how profitable their Walmart and McDonald's stocks are. Why can't teachers be compensated like people at McDonald's? And why do kids fail tests? The tabloids, Michelle Rhee and Bill Gates proclaim it must be the teachers. After all, KIPP works miracles with these kids, getting incredible results with the half of them who don't drop out and return to public schools. But in public schools, when kids drop out, they don't return to KIPP! Therefore public schools are terrible. Most importantly, teachers do much more than test prep. It's very frustrating to me because it's my job to teach newcomers English, and the test they're required to take, the NYS English Regents, does not measure that at all. I've actually been pretty good at making them pass it, but I'm 100% certain the skill of passing the Regents exam translates to absolutely zero of the skills they actually need. As for college readiness, kids who don't know English will certainly be taking remedial courses to catch up. I know because I've taught them, and in fact I could teach kids what they need rather than prepping them for a test that's largely impractical. Learning a language can be a lot of fun, as conversation, discussion, and projects can be very stimulating. Test prep sucks. But I will do it if my kids need it. And while we all like money, that, in fact, is what motivates teachers. I can't necessarily make a kid who came from China two months ago write enough to pass the English Regents. That's not my fault, or my school's fault. There are a million variables that cause kids to fail tests. Teachers do what we can, but with real income having gone nowhere since 1983, with parents working round the clock just to keep up, with Democrats no different than Republicans and a disappearing middle class, you aren't going to see an amazing rise in test scores anytime soon. Unless, of course, you dumb down the tests like New York did when Mayor4Life proclaimed himself a genius and bought himself an illegal third term as a reward. Yes, we are a team. But teachers are just part of it. And until folks like Barack Obama and Andrew Cuomo start working with the team rather than trying to figure how to best dismantle that pesky middle class and appease billionaires, we won't see that uptick in test scores they publicly claim to care about, the one they use as a hammer against teachers, the last remaining vestige of vibrant unionism in this increasingly corporate entity we call the United States of America. I do my part. I stand up for working people in many ways, as do thousands of my colleagues. What we really need, though, are millions more standing with us. Because until we pass that test, the ones Bill Gates publicly complains about will be as meaningless as the ones NY State makes my poor ESL students take. Follow by Email Humbly Presented By... Search this blog Disclaimer Views expressed herein are solely those of the author or authors, and do not reflect views of my employers, the United Federation of Teachers, the MORE Caucus or any other union caucus. Stories herein containing unnamed or invented characters are works of fiction. Names, characters, businesses, places, events and incidents are either the products of the author’s imagination or used in a fictitious manner. Any resemblance to actual persons, living or dead, or actual events is purely coincidental./*********************************************************************************************************//** * @file NVIC/External_Interrupt/ht32f5xxxx_01_it.c * @version $Rev:: 2970 $ * @date $Date:: 2018-08-03 #$ * @brief This file provides all interrupt service routine. ************************************************************************************************************* * @attention * * Firmware Disclaimer Information * * 1. The customer hereby acknowledges and agrees that the program technical documentation, including the * code, which is supplied by Holtek Semiconductor Inc., (hereinafter referred to as "HOLTEK") is the * proprietary and confidential intellectual property of HOLTEK, and is protected by copyright law and * other intellectual property laws. * * 2. The customer hereby acknowledges and agrees that the program technical documentation, including the * code, is confidential information belonging to HOLTEK, and must not be disclosed to any third parties * other than HOLTEK and the customer. * * 3. The program technical documentation, including the code, is provided "as is" and for customer reference * only. After delivery by HOLTEK, the customer shall use the program technical documentation, including * the code, at their own risk. HOLTEK disclaims any expressed, implied or statutory warranties, including * the warranties of merchantability, satisfactory quality and fitness for a particular purpose. * * <h2><center>Copyright (C) Holtek Semiconductor Inc. All rights reserved</center></h2> ************************************************************************************************************/ /* Includes ------------------------------------------------------------------------------------------------*/ #include "ht32.h" #include "ht32_board.h" /** @addtogroup HT32_Series_Peripheral_Examples HT32 Peripheral Examples * @{ */ /** @addtogroup NVIC_Examples NVIC * @{ */ /** @addtogroup External_Interrupt * @{ */ /* Private constants ---------------------------------------------------------------------------------------*/ #define DELAY_TIME 0x7FFFFF /* Private function prototypes -----------------------------------------------------------------------------*/ static void Delay(vu32 count); /* Global functions ----------------------------------------------------------------------------------------*/ /*********************************************************************************************************//** * @brief This function handles NMI exception. * @retval None ************************************************************************************************************/ void NMI_Handler(void) { } /*********************************************************************************************************//** * @brief This function handles Hard Fault exception. * @retval None ************************************************************************************************************/ void HardFault_Handler(void) { #if 1 static vu32 gIsContinue = 0; /*--------------------------------------------------------------------------------------------------------*/ /* For development FW, MCU run into the while loop when the hardfault occurred. */ /* 1. Stack Checking */ /* When a hard fault exception occurs, MCU push following register into the stack (main or process */ /* stack). Confirm R13(SP) value in the Register Window and typing it to the Memory Windows, you can */ /* check following register, especially the PC value (indicate the last instruction before hard fault).*/ /* SP + 0x00 0x04 0x08 0x0C 0x10 0x14 0x18 0x1C */ /* R0 R1 R2 R3 R12 LR PC xPSR */ while (gIsContinue == 0) { } /* 2. Step Out to Find the Clue */ /* Change the variable "gIsContinue" to any other value than zero in a Local or Watch Window, then */ /* step out the HardFault_Handler to reach the first instruction after the instruction which caused */ /* the hard fault. */ /*--------------------------------------------------------------------------------------------------------*/ #else /*--------------------------------------------------------------------------------------------------------*/ /* For production FW, you shall consider to reboot the system when hardfault occurred. */ /*--------------------------------------------------------------------------------------------------------*/ NVIC_SystemReset(); #endif } /*********************************************************************************************************//** * @brief This function handles SVCall exception. * @retval None ************************************************************************************************************/ void SVC_Handler(void) { } /*********************************************************************************************************//** * @brief This function handles PendSVC exception. * @retval None ************************************************************************************************************/ void PendSV_Handler(void) {
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on the defendant's part. This burden is met by proof demonstrating that the defendant public official's actions "violated clearly established constitutional law." 25 Rich, 841 F.2d at 1563-64 (quoting Zeigler v. Jackson, 716 F.2d 847, 849 (11th Cir.1983) (per curiam)); Hutton, 919 F.2d at 1537. Under the Zeigler/Rich formulation of the objective-reasonableness test, a government official proves that he acted within his discretionary authority by showing " 'objective circumstances which would compel the conclusion that his actions were undertaken pursuant to the performance of his duties and within the scope of his authority.' " Rich, 841 F.2d at 1564 (quoting Barker v. Norman, 651 F.2d 1107, 1121 (5th Cir. Unit A July 1981)); Hutton, 919 F.2d at 1537. 26 The second component of the Zeigler/Rich objective-reasonableness test is divided into two analytical subparts. Rich, 841 F.2d at 1563-64 (citing Mitchell, 472 U.S. at 528, 105 S.Ct. at 2816); Hutton, 919 F.2d at 1538. First, the reviewing court must decide whether the applicable law was clearly established when the governmental action in question occurred. Rich, 841 F.2d at 1563-64 (citing Harlow, 457 U.S. at 818, 102 S.Ct. at 2738); Hutton, 919 F.2d at 1538; see Barts v. Joyner, 865 F.2d 1187, 1190 (11th Cir.) ("To defeat a qualified immunity defense, plaintiff bears the burden of showing that 'the legal norms allegedly violated by the defendant were clearly established at the time of the challenged actions or,... the law clearly proscribed the actions the defendant... took.' " (quoting Mitchell, 472 U.S. at 528, 105 S.Ct. at 2816)) cert. denied, --- U.S. ----, 110 S.Ct. 101, 107 L.Ed.2d 65 (1989). "Clearly established," is defined, with reference to the right that the official is alleged to have violated, as meaning that "[t]he contours of the right must be sufficiently clear that a reasonable official would understand that what he is doing violates that right."14 Anderson v. Creighton, 483 U.S. 635, 640, 107 S.Ct. 3034, 3039, 97 L.Ed.2d 523 (1987). Second, the court must determine whether there is a genuine issue of fact concerning the government official's conduct being in violation of clearly established law. Rich, 841 F.2d at 1563-65 (citing Mitchell, 472 U.S. at 528, 105 S.Ct. at 2816); Hutton, 919 F.2d at 1538; see, e.g., Herren v. Bowyer, 850 F.2d 1543, 1546-47 (11th Cir.1988); Webb v. Ethridge, 849 F.2d 546, 550 (11th Cir.1988) (Genuine issues of material fact precluded summary judgment based on qualified immunity.). Accordingly, we shall assess Courson's claims against Roy with respect to seizure, unreasonable force and abandonment under the Zeigler/Rich analysis. 1. Seizure 27 Courson has alleged that Roy violated her Fourth and Fourteenth Amendment protections against detention without probable cause. Personal encounters between law enforcement officers and citizens are "seizures" on occasions "when the officer, by means of physical force or show of authority, has in some way restrained the liberty of a citizen."15 Terry v. Ohio, 392 U.S. 1, 19 n. 16, 88 S.Ct. 1868, 1879 n. 16, 20 L.Ed.2d 889 (1968). Roy seized Courson along with her companions because she was not free to go until Roy so informed her after the investigation and arrest of her male companions. Therefore, we must evaluate Roy's actions with respect to Courson under the Zeigler/Rich test to determine whether he is entitled to qualified immunity for his conduct in May, 1985. 28 Our initial determination is whether Roy was acting within the scope of his discretionary authority when he stopped and detained Courson and her companions. It is undisputed that Roy was on duty when he stopped the vehicle. Courson has neither challenged Roy's probable cause in making the stop, because she acknowledges that their vehicle was exceeding the lawful speed limit, nor questioned the arrests of her companions.16 We conclude that these objective circumstances demonstrate that Roy was acting within the purview of his discretionary authority when he stopped the vehicle in which Courson and her companions were riding and detained them. See Hutton, 919 F.2d at 1537; Rich, 841 F.2d at 1564. 29 The burden thereafter shifts to Courson to show that Roy's conduct violated clearly established constitutional law. As opposed to the initial stop of the vehicle, Courson apparently objects to her requested exit from the vehicle and subsequent detention. We will limit our analysis of Courson's seizure to these issues. Under this aspect of the Zeigler/Rich analysis, we must determine whether the applicable law was clearly established when Roy detained Courson with her companions in May, 1985. Rich, 841 F.2d at 1563-64. Because probable cause for the stop existed for the male driver only, we find that our analysis regarding the law applicable to Courson is analogous to a warrantless investigatory stop under Terry rather than a custodial arrest.17 See United States v. Neu, 879 F.2d 805, 808 (10th Cir.1989) ("A traffic stop... is ordinarily a limited seizure within the meaning of the Fourth Amendment" and "is subject to the less rigorous requirements of Terry... rather than the more stringent constitutional strictures of a custodial arrest."); see also United States v. Roper, 702 F.2d 984, 985 (11th Cir.1983) ("If there was merely an investigatory stop,... only reasonable suspicion is required to pass constitutional muster."). 30 "The Fourth and Fourteenth Amendments are implicated in this case because stopping an automobile and detaining its occupants constitute a'seizure' within the meaning of those Amendments, even though the purpose of the stop is limited and the resulting detention quite brief." Delaware v. Prouse, 440 U.S. 648, 653, 99 S.Ct. 1391, 1396, 59 L.Ed.2d 660 (1979). The Court has recognized the constitutionality of stops of automobiles and the detention of the occupants for questioning to determine if illegal aliens are present, when officers have a reasonable suspicion. See, e.g., United States v. Cortez, 449 U.S. 411, 101 S.Ct. 690, 66 L.Ed.2d 621 (1981); United States v. Brignoni-Ponce, 422 U.S. 873, 95 S.Ct. 2574, 45 L.Ed.2d 607 (1975). Explaining the necessity of investigatory detentions generally, the Court stated: 31 The Fourth Amendment does not require a policeman who lacks the precise level of information necessary for probable cause to arrest to simply shrug his shoulders and allow a crime to occur or criminal to escape. On the contrary, Terry recognizes that it may be the essence of good police work to adopt an intermediate response. A brief stop of a suspicious individual, in order to determine his identity or to maintain the status quo momentarily while obtaining more information, may be most reasonable in light of the facts known to the officer at the time. 32 Adams v. Williams, 407 U.S. 143, 145-46, 92 S.Ct. 1921, 1923, 32 L.Ed.2d 612 (1972) (citations omitted); see INS v. Delgado, 466 U.S. 210, 216, 104 S.Ct. 1758, 1762, 80 L.Ed.2d 247 (1984) ("[P]olice questioning, by itself, is unlikely to result in a Fourth Amendment violation."). 33 The Supreme Court has directed a balancing of competing interests in determining the unreasonableness of a seizure within the meaning of the Fourth Amendment: 34 We must balance the nature and quality of the intrusion on the individual's Fourth Amendment interests against the importance of the governmental interests alleged to justify the intrusion. When the nature and extent of the detention are minimally intrusive of the individual's Fourth Amendment interests, the opposing law enforcement interests can support a seizure based on less than probable cause. 35 United States v. Place, 462 U.S. 696, 703, 103 S.Ct. 2637, 2642, 77 L.Ed.2d 110 (1983); see Prouse, 440 U.S. at 654, 99 S.Ct. at 1396 ("[T]he permissibility of a particular law enforcement practice is judged by balancing its intrusion on the individual's Fourth Amendment interests against its promotion of legitimate governmental interests." (footnote omitted)). This court has determined that "[t]he distinction between an arrest and an investigatory stop depends upon the nature and degree of the intrusion under all the facts of the
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. How can I do this? Is there any method to accomplish this goal? A: Yes, you can use setMouseEnabled(x,y) on the view box, e.g. PlotWidget. See http://www.pyqtgraph.org/documentation/_modules/pyqtgraph/graphicsItems/ViewBox/ViewBox.html#ViewBox.setMouseEnabled The Domestic Violence Unit of the Kingsport Police Department supports the Patrol Division as a specialized investigative unit concerned with domestic violence and stalking issues. The unit is comprised of one officer who reviews all domestic assault, domestic vandalism, and order of protection violations that are reported to the Kingsport Police Department. With the help of the community, the Domestic Violence Unit continues to provide cell phones to victims of domestic abuse. The Abused Women Active Response Emergency (A.W.A.R.E.) program is still active. These programs continue to provide the victims of domestic abuse with enhanced protection and security during their time of need. Additionally, the Kingsport Police Department’s Domestic Violence Unit has remained an active voice with the Second Judicial District Domestic Violence Task Force – “The Front Line”. As many as four million women in this country will suffer some kind of violence at the hands of her husband or boyfriend. Very few will tell anyone – not a friend, a relative, a neighbor, or the police. Victims of domestic violence come from all walks of life – all cultures, all income groups, all ages, all religions. They share feelings of helplessness, isolation, guilt, fear, and shame. All hope it won’t happen again, but often it does. ARE YOU ABUSED? Does the person you love… “Track” all of your time? Constantly accuse you of being unfaithful? Discourage your relationships with family and friends? Prevent you from working or attending school? Criticize you for little things? Anger easily when drinking or on drugs? Control all finances and force you to account in detail for what you spend? Humiliate you in front of others? Destroy personal property or sentimental items? Hit punch, slap, kick, or bite you or the children? Use or threaten to use a weapon against you? Threaten to hurt you or the children? Force you to have sex against your will? If you find yourself saying yes, it’s time to get help. DON’T IGNORE THE PROBLEM Talk to someone. Part of the abusers power comes from secrecy. Victims are often ashamed to let anyone know about intimate family problems. Go to a friend or neighbor, or call a domestic violence hotline to talk to a counselor. Plan ahead and know what you will do if you are attacked again. If you decide to leave, choose a place to go; set aside some money. Put important papers together — marriage license, birth certificates, check books — in a place where you can get them quickly. Learn to think independently. Try to plan for the future and set goals for yourself. IF YOU ARE HURT, WHAT CAN YOU DO? There are no easy answers, but there are things you can do to protect yourself. Call the police or sheriff. Assault, even by family members, is a crime. The police often have information about shelters and other agencies that help victims of domestic violence. Leave, or have someone come and stay with you. Go to a battered women’s shelter – call a crisis hotline in your community or a health center to locate a shelter if you believe that you, and your children, are in danger – leave immediately. Get medical attention from your doctor or a hospital emergency room. Ask the staff to photograph your injuries and keep detailed records in case you decide to take legal action. Contact your family court for information about a civil protection order that does not involve criminal charges or penalties. HAVE YOU HURT SOMEONE IN YOUR FAMILY? Accept the fact that your violent behavior will destroy your family. Be aware that you break the law when you physically hurt someone. Take responsibility for your actions and get help. When you feel tension building, get away. Work off the angry energy through a walk, a project, a sport. Call a domestic violence hotline or health center and ask about counseling and support groups for people who batter. THE HIGH COSTS OF DOMESTIC VIOLENCE Men and women who follow their parents’ example and use violence to solve conflicts are teaching the same destructive behavior to their children. Jobs can be lost or careers stalled because of injuries, arrests, or harassments. Lives are lost when violence results in death. TAKE A STAND! Reach out to someone you believe is a victim of family violence, or to someone you think is being abusive. Don’t give up easily – change takes time. Ending the family’s isolation is a critical first step. Urge organizations and businesses to raise community awareness by hosting speakers on domestic violence launching public education campaigns, and raising funds for shelters and hotlines. Ask the local newspaper, radio station, or television station to examine the problem and publicize resources in the community through special features and forums. Form coalitions or “watchdog” groups to monitor the response of local law enforcement agencies and courts. Offer praise where appropriate and demand reform when necessary. Most communities offer resources for victims of family violence. Check your telephone directory or ask a law enforcement agency.publications per page sort by order C. Weng, B. Curless, and I. Kemelmacher-Shlizerman. (2018)cite arxiv:1812.02246Comment: The project page is at https://grail.cs.washington.edu/projects/wakeup/, and the supplementary video is at https://youtu.be/G63goXc5MyU.Guest essay by Eric Worrall President Obama has announced a climate “pact” with Canada; but this executive action seems likely to once again raise questions about the limits of executive authority. U.S., Canada Sign Pact to Fight Climate Change Countries say they will cut methane emissions and try to sign Paris climate deal. WASHINGTON (Reuters) – The United States and Canada agreed joint steps on Thursday to fight climate change, including cutting methane emissions from oil and gas operations and signing last year’s Paris climate deal “as soon as feasible.” The agreement came as Canada’s new Prime Minister Justin Trudeau and President Barack Obama met at the White House. Methane, which can leak from pipelines and valves, is a powerful greenhouse gas, with up to 80 times the potential of carbon dioxide to trap the planet’s heat. The agreement can do “even more to protect our countries and our communities, especially in the Arctic, from climate change,” Obama said during a welcoming ceremony for Trudeau. … The countries committed to cutting emissions of methane by 40 to 45 percent below 2012 levels by 2025, to take steps to fight climate change in the Arctic, and to speed development of green technologies. The U.S. Environmental Protection Agency will begin developing regulations for methane emissions from existing oil and gas sources immediately and “will move as expeditiously as possible to complete this process,” the joint agreement said.# Copyright (c) 2020 Digital Asset (Switzerland) GmbH and/or its affiliates. All rights reserved. # SPDX-License-Identifier: Apache-2.0 load("//bazel_tools:scala.bzl", "da_scala_library") da_scala_library( name = "rs-grpc-testing-utils", srcs = glob([ "src/main/scala/**/*.scala", ]), tags = [ "maven_coordinates=com.daml:rs-grpc-testing-utils:__VERSION__", ], visibility = [ "//visibility:public", ], deps = [ "@maven//:io_grpc_grpc_stub", ], ) The field of the invention is load balancing, and in particular using a firewall to perform load balancing. A known load balancer is configured as a proxy server that receives a packet of information, performs some analysis on the packet to select a destination server, and then forwards the packet to the selected server. However, in order to perform load balancing on a packet, the packet must be addressed by its sender to the balancer, not to the packet""s actual intended destination. This disadvantageously adds an additional layer of complexity in the addressing scheme for the sender to obtain service from the destination server. Further, a known balancer performs substantial analysis of each packet, which absorbs processor resources of the balancer, adds a delay to the delivery of the packet to its actual intended destination, and increases the chances that a packet will be erroneously dropped. A firewall regulates the flow of packetized information. A packet includes a header and a payload. The header includes header information (header parameters), which can include a source and destination address for the packet, as well as source and destination port numbers, a protocol number, a physical location identifier, flags, a priority indicator (ROUTINE, URGENT, etc.), security information, etc. The payload includes the data meant to be conveyed by the packet from its source to its intended destination. A known firewall is placed between the packet""s source and intended destination, where
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correlated to lower CFTR internalization, (A and B) whereas caveolin 1 depletion had no impact upon PM- and internalized CFTR amounts. Then, 48 h after transfection with indicated siRNA, cells were treated with 10 μM ML141 for 30 min or 10 μM wiskostatin for 120 min, before labelling and during the 5 min internalization period. Results were compared to vehicle treatment conditions. (C) When dynamin 2 is depleted, CFTR internalization increase upon pharmacological treatments is abolished. Data represent means ± SEM of 3 independent experiments, each performed in duplicate. \*\*\*: p\<0.001, \*\*: p\<0.01, \*: p\<0.05, ns: non significant.](pone.0118943.g004){#pone.0118943.g004} Pharmacological inhibitors of Cdc42 pathway decrease actin polymerization {#sec017} ------------------------------------------------------------------------- As Cdc42 pathway is one of the regulation mechanisms involved in actin cytoskeleton remodelling, we checked the impact of previously applied treatments upon actin cytoskeleton integrity in CFBE-wtCFTR cells. First, we visualized the consequences of ML141 and wiskostatin treatments upon actin cytoskeleton organization by means of fluorescent confocal imagery, on a monolayer of polarized CFBE-wtCFTR cells grown on a permeable support ([Fig. 5A](#pone.0118943.g005){ref-type="fig"}). As depicted in transversal sections, ZO-1 immunostaining of tight junctions was not modified by the treatments. This further suggests that the polarity of the cells was not disrupted. In control condition (*i*.*e*. vehicle treatment), phalloidin staining highlighted cortical actin cytoskeleton above the apical and basolateral membranes. Upon 100 μM wiskostatin treatment, actin staining appeared blurry and scattered throughout the cell cytosol when compared to control. This severe disturbance of cytoskeleton organization is in accordance with the high level of cell mortality that we observed with the above-mentioned wiskostatin concentration. Conversely, in the presence of 10 μM wiskostatin or 10 μM ML141, the actin patterns within the cells appeared similar to the ones produced under control conditions. ![Pharmacological treatments decrease actin polymerization.\ (A) Cell shape, polarity and peripheral actin cytoskeleton pattern appear preserved upon 10 μM wiskostatin or 10 μM L141 treatments compared to vehicle treatment, whereas actin is scattered throughout the cytoplasm with 100 μM wiskostatin. Cells were grown on Transwell permeable support until a monolayer was established. After ML141 or wiskostatin treatments at the indicated concentrations, ZO-1 proteins were immunostained (green) and actin was tracked using phalloidin-TRITC (red). TO-PRO-3 was used as a cell nucleus marker (blue). Transversal section images were acquired with a confocal microscope. Scale bars represent 20 μm. (B) Pharmacological inhibitions of Cdc42 pathway reduce fibrillar (F-) actin content. Cells were incubated with 10 μM ML141 or 10 μM wiskostatin, and 10 μM cytochalasin B was used as an F-actin polymerization inhibition positive control treatment, whereas 1% DMSO (v/v) was used as negative control treatment. Actin-bound phalloidin-FITC was methanol-extracted and fluorescence measurements were performed. Results were normalized to protein amount and the relative F-actin contents are expressed as the percentage of DMSO control condition in histograms. Data represent means ± SEM of 3 independent experiments, each performed in triplicate. \*\*: p\<0.01, \*: p\<0.05.](pone.0118943.g005){#pone.0118943.g005} We then quantified fibrillar (F-) actin amounts after pharmacological treatments: in both cases, we obtained a significant decrease in F-actin content ([Fig. 5B](#pone.0118943.g005){ref-type="fig"}). The values were comparable to the decrease elicited by cytochalasin B, a compound used to directly inhibit actin polymerization by blocking monomer addition. Even though the polarity and the actin filament scaffolding of the cells appeared unaltered at the imaging resolution we used, the polymerized actin amount was lowered upon treatments with these compounds. As discussed below, differences in actin polymerization status after pharmacological treatments may account for the destabilization of PM-CFTR, and hence for its increased internalization. Cdc42 depletion does not alter actin polymerization {#sec018} --------------------------------------------------- To interfere with Cdc42 pathway in CFBE-wtCFTR cells, we applied a siRNA knock-down approach in order to deplete cells in the proteins that we had pharmacologically inhibited in the first part of our study. The efficiencies of these depletions were assessed by real-time RT-PCR and by Western blot ([S3 Fig](#pone.0118943.s003){ref-type="supplementary-material"}.). We first investigated the impact of these depletions upon polymerized actin content. As expected, N-WASP-depleted cells exhibited a significant decrease of F-actin amount ([Fig. 6](#pone.0118943.g006){ref-type="fig"}), and the consequences appear similar to those observed with wiskostatin inhibition of N-WASP. By contrast, when Cdc42 was depleted, no significant difference in F-actin content was observed when compared with cells transfected with negative control siRNA ([Fig. 6](#pone.0118943.g006){ref-type="fig"}), whereas ML141 inhibition of Cdc42 led to a decrease in polymerized actin content. Whatever may account for this difference, these findings suggest that alterations of CFTR trafficking resulting from Cdc42 depletion would not be triggered by actin scaffold-dependent mechanisms. ![Cdc42 depletion does not alter fibrillar actin content.\ RNAi-mediated depletions of Cdc42 or N-WASP were performed for 48 h and F-actin content was quantified as described in [Fig. 5](#pone.0118943.g005){ref-type="fig"} legend. As displayed in histograms, N-WASP depletion alone elicited a decrease of polymerized actin content, compared with negative control RNAi condition. Data represent means ± SEM of 3--8 independent experiments, each performed in triplicate. \*\*: p\<0.01, ns: non-significant.](pone.0118943.g006){#pone.0118943.g006} Cdc42 depletion increases CFTR activity and total CFTR amount {#sec019} ------------------------------------------------------------- We first investigated the impact of Cdc42 or N-WASP depletions upon CFTR channel function. We performed iodide efflux experiments 48 h after siRNA transfections: in N-WASP-depleted cells, CFTR activity decreased, whereas in Cdc42-depleted cells it increased ([Fig. 7](#pone.0118943.g007){ref-type="fig"}). In the first case, there are pronounced similarities to the consequences of wiskostatin treatment. As for Cdc42 depletion impact, it contrasts with the previously observed ML141inhibition of CFTR channel activation. ![Cdc42 depletion increases CFTR channel activation.\ (A) In non-stimulated CFBE-wtCFTR cells (basal) or upon stimulation of CFTR activity by forskolin (Fsk, 10 μM) + genistein (Gst, 30 μM), iodide efflux curves were obtained after 48 h of siRNA-mediated depletions (negative control, Cdc42 or N-WASP), n = 4 in each condition. (B) Histograms show the mean relative rates of CFTR activity. Results obtained after Cdc42 and N-WASP depletions were compared to control RNAi condition. Means ± SEM are indicated. \*\*: p\<0.01, \*: p\<0.05.](pone.0118943.g007){#pone.0118943.g007} We then confronted these functional data with the quantification of CFTR protein amount: N-WASP depletion resulted in only a small decrease, while Cdc42 indeed elicited a 37% increase of total CFTR amount ([Fig. 8A and 8B](#pone.0118943.g008){ref-type="fig"}). Nevertheless, when protein synthesis was inhibited by cycloheximide for the last 24 h of the Cdc42 depletion, we observed no difference of total CFTR amount, compared to control ([S4 Fig](#pone.0118943.s004){ref-type="supplementary-material"}.). This suggests that Cdc42 may be involved in the stability of newly synthesized CFTR protein in early steps of its processing. We checked by real-time RT-PCR to make sure that neither of these depletions had an impact upon *CFTR* mRNA level (not shown), so the consequences may lie in post-transcriptional events such as translation, folding control, maturation or degradation of the protein. However, Western blots exhibited no apparent alteration of maturation from band B to band C, a process that terminates within the Golgi apparatus and appears unaffected. ![Impact of Cdc42 or N-WASP depletions upon CFTR amount and internalization.\ RNAi-mediated depletions of Cdc42 or N-WASP were performed for 48 h. We then used biotinylation experiments to evaluate CFTR amount at the cell surface and CFTR internalization, as described in [Fig. 2](#pone.0118943.g002){ref-type="fig"} legend. (A) Representative Western blots and (B-D) histograms summarizing the data are presented. Following Cdc42 depletion, (B) total CFTR amount in whole cell lysate, (C) as well as CFTR amount at the plasma membrane, had increased compared to negative control RNAi conditions.
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2323, 2822, 7479, 313, 23, 1572, 187, 5817, 15699, 3282, 273, 4780, 313, 24, 1572, 187, 5817, 1359, 3110, 7033, 10165, 281, 1786, 6973, 313, 18, 1572, 187, 5817, 11431, 1387, 19501, 7147, 4688, 16, 41293, 1368, 25221, 19501, 313, 19, 1572, 187, 5817, 23410, 434, 2250, 2098, 313, 18, 10, 29653, 318, 342, 3625, 1557, 5817, 29787, 314, 11269, 313, 23, 1572, 187, 5817, 13135, 285, 897, 275, 1524, 14, 2606, 342, 1363, 313, 24, 1572, 187, 5817, 49230, 34854, 323, 747, 941, 313, 19, 1572, 187, 5817, 27604, 275, 253, 444, 9914, 27, 29886, 3148, 13, 2289, 21855, 7211, 13, 3110, 7342, 285, 15938, 313, 740, 1572, 187, 5817, 29712, 6164, 12537, 4750, 281, 897, 941, 342, 1363, 313, 24, 1572, 187, 5817, 10834, 281, 14409, 17191, 313, 18, 10, 187, 187, 4118, 4033, 8856, 281, 14631, 5875, 5243, 383, 9250, 1712, 4538, 26, 94, 187, 187, 19799, 841, 5252, 14, 3024, 3625, 1557, 11967, 13, 627, 369, 2761, 6447, 4345, 326, 1363, 574, 2709, 15938, 281, 6153, 285, 38933, 5875, 5243, 383, 9250, 15, 22397, 2289, 281, 5875, 12134, 285, 2940, 494, 25237, 13, 1698, 1786, 31520, 13, 285, 2709, 11771, 23971, 18123, 3486, 247, 3110, 434, 3745, 281, 3297, 5875, 10159, 273, 616, 16038, 449, 35797, 2512, 434, 247, 13407, 1895, 273, 2739, 3126, 28, 359, 476, 513, 247, 1652, 347, 3625, 1557, 27586, 533, 352, 434, 247, 625, 13407, 1895, 9739, 35485, 476, 2940, 533, 952, 434, 25237, 6403, 626, 4999, 1051, 13174, 403, 9202, 281, 2940, 275, 616, 25237, 4536, 28, 1529, 5691, 342, 776, 1363, 310, 7848, 1430, 273, 5875, 2739, 285, 1659, 281, 5763, 285, 1051, 7955, 1256, 28, 597, 452, 594, 1199, 4073, 275, 616, 4852, 326, 2739, 905, 1257, 3217, 253, 3662, 323, 616, 4073, 696, 9739, 6080, 273, 905, 783, 15938, 696, 310, 905, 25831, 696, 1786, 31520, 28, 8327, 310, 627, 533, 597, 816, 1053, 626, 2096, 752, 281, 513, 3, 35797, 187, 187, 5279, 4202, 841, 15938, 310, 2570, 13, 285, 2223, 3345, 253, 19929, 273, 752, 3133, 1896, 949, 247, 3625, 1557, 14235, 449, 35797, 1447, 29139, 696, 878, 247, 2257, 273, 12925, 285, 1133, 5877, 285, 352, 434, 1892, 281, 513, 326, 275, 247, 3625, 1557, 4143, 9739, 4509, 247, 11723, 1127, 273, 1859, 13, 359, 1472, 1663, 417, 873, 598, 281, 513, 326, 2644, 1232, 905, 1171, 25859, 1475, 14898, 2544, 28653, 436, 310, 247, 1077, 3739, 1566, 273, 1557, 3, 35797, 187, 187, 4118, 29621, 273, 14898, 11237, 2086, 1712, 4538, 740, 94, 187, 187, 3074, 11967, 3636, 253, 8327, 281, 452, 690, 275, 14, 498, 17841, 3057, 342, 253, 3110, 281, 23070, 253, 3909, 8401, 12212, 2086, 15, 9225, 5852, 6566, 326, 436, 651, 1361, 41509, 1363, 281, 6604, 285, 3297, 3939, 275, 824, 247, 2086, 449, 35797, 45392, 4861, 1060, 13, 651, 320, 9386, 13, 281, 452, 247, 12461, 382, 1060, 327, 253, 5254, 281, 923, 1363, 1078, 390, 846, 441, 905, 3088, 5285, 28653, 1361, 1363, 564, 625, 27340, 9739, 1147, 434, 1270, 359, 1472, 2509, 3072, 4323, 13, 533, 352, 434, 1335, 327, 441, 1051, 1231, 452, 281, 755, 731, 1223, 597, 1472, 1060, 13, 604, 352, 369, 3095, 1066, 253, 7423, 13, 352, 3198, 281, 320, 387, 253, 673, 273, 253, 4143, 281, 1056, 253, 11716, 625, 5919, 285, 281, 41509, 253, 3110, 281, 513, 352, 285, 594, 253, 3110, 4850, 752, 597, 878, 387, 253, 673, 273, 253, 4143, 3, 35797, 187, 187, 6080, 11967, 13876, 1880, 627, 812, 320, 247, 3114, 14, 3169, 4809, 281, 253, 2086, 28, 436, 651, 1361, 1363, 3297, 9583, 407, 1146, 625, 42838, 13, 18522, 40744, 1037, 13, 285, 3471, 32414, 7996, 281, 1363, 8, 3198, 13, 285, 407, 6941, 1363, 281, 3894, 5300, 285, 5697, 342, 1016, 643, 449, 35797, 10342, 5547, 2175, 7091, 8905, 25859, 28, 275, 14, 10816, 4430, 1904, 626, 513, 667, 1805, 685, 253, 8905, 4430, 984, 952, 1053, 626, 921, 598, 323, 30219, 28, 309, 1158, 8905, 310, 2234, 9739, 29139, 452, 5300, 285, 5697, 326, 812, 320, 1663, 9371, 323, 643, 1363, 28, 751, 247, 29517, 985, 390, 9628, 275, 1387, 12941, 3, 35797, 187, 187, 510, 6349, 273, 8928, 285, 5054, 7340, 369, 5439, 407, 1142, 11967, 1969, 14898, 5659, 403, 760, 5547, 604, 597, 476, 2525, 253, 3110, 835, 597, 403, 285, 1056, 2544, 1561, 2176, 1461, 1100, 449, 35797, 36, 503, 8572, 4623, 12398, 5971, 403, 247, 1943, 7741, 359, 452, 9739, 42, 7156, 273, 247, 7824, 1387, 275, 512, 253, 4623, 25237, 326, 574, 952, 665, 7560, 253, 987, 11515, 3, 35797, 187, 187, 4118, 40283, 273, 2086, 6973, 281, 253, 3625, 1557, 11716, 1712, 4538, 883, 94, 187, 187, 6407, 285, 31971, 13, 11967, 3078, 281, 871, 253, 3110, 434, 7342, 275, 253, 2086, 1969, 752, 497, 597, 285, 849, 497, 597, 3715, 15, 40828, 247, 3110, 434, 7342, 651, 1361, 342, 49956, 44235, 10159, 273, 1880, 253, 3110, 369, 327, 3540, 390, 574, 13547, 3212, 275, 4804, 616, 7342, 449, 35797, 7371, 7342, 497, 253, 3110, 2444, 327, 28, 690, 3282, 273, 835, 253, 3110, 369, 387, 275, 2426, 273, 16038, 285, 1735, 5018, 3, 35797, 187, 187, 11509, 5852, 3636, 253, 878, 323, 247, 3282, 273, 253, 3110, 434, 13226, 342, 253, 8401, 12212, 2086, 28, 436, 1491, 369, 14320, 5667, 281, 8925, 253, 5230, 2847, 273, 247, 575, 15325, 434, 4248, 273, 2323, 275, 4804, 616, 7342, 449, 35797, 1394, 476, 1007, 387, 1232, 390, 6454, 28, 604, 597, 403, 15299, 285, 849, 2223, 597, 1472, 2509, 352, 285, 452, 359, 2326, 667, 1543, 275, 616, 2801, 275, 2087, 9739, 510, 1943, 2523, 310, 326, 594, 1643, 273, 619, 1363, 403, 9583, 275, 667, 1039, 13, 309, 816, 971, 281, 871, 326, 597, 1472, 9583, 13, 3095, 310, 12669, 275, 327, 731, 13, 597, 1472, 1907, 4780, 3579, 3, 35797, 187, 187, 11509, 5852, 671, 3078, 247, 3282, 273, 253, 3110, 434, 15938, 281, 2323, 1969, 1880, 432, 21855, 7211, 390, 432, 253, 3110, 3746, 1969, 281, 8338, 841, 2007, 342, 253, 3110, 285, 1287, 5827, 281, 11399, 731, 15, 9225, 5852, 27364, 3078, 281, 1329, 616, 1363, 275, 616, 6031, 275, 5875, 3811, 28, 597, 3047, 436, 9554, 347, 247, 1039, 281, 35919, 616, 18766, 6297, 4390, 449, 35797, 42, 651, 2389, 281, 871, 752, 434, 9369, 594, 672, 309, 923, 253, 3110, 309, 476, 28432, 13, 751, 247, 5890, 1133, 2727, 432, 253, 2086, 28, 651, 871, 359, 497, 4933, 5185, 7535, 285, 10345, 626, 9602, 1016, 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275, 1524, 14, 2606, 342, 1363, 1309, 14235, 12941, 15, 3808, 3636, 253, 6387, 273, 2970, 34854, 672, 627, 369, 747, 2425, 432, 253, 3110, 275, 253, 985, 449, 35797, 1909, 3517, 347, 368, 2412, 275, 281, 253, 8326, 310, 627, 247, 1039, 281, 871, 326, 253, 3110, 310, 275, 253, 2086, 1051, 12157, 840, 309, 812, 923, 4266, 14707, 281, 897, 352, 15, 309, 476, 923, 4266, 14707, 281, 897, 253, 4465, 1491, 281, 2312, 342, 253, 3110, 9739, 17304, 320, 5322, 604, 352, 369, 275, 253, 444, 6784, 13, 651, 4684, 281, 253, 905, 290, 603, 696, 3110, 905, 15352, 696, 9739, 3864, 5179, 314, 651, 320, 9828, 28, 309, 1053, 626, 1158, 359, 1472, 1469, 281, 923, 1543, 594, 4541, 3, 35797, 187, 187, 11509, 5852, 3078, 253, 941, 275, 253, 444, 9914, 342, 29886, 13, 3477, 281, 4665, 12646, 273, 253, 1794, 7480, 941, 347, 973, 347, 2289, 281, 253, 21855, 7211, 285, 3636, 15938, 449, 35797, 1394, 923, 247, 4736, 1969, 597, 1472, 4759, 327, 2801, 13, 2502, 327, 24692, 28, 3477, 281, 923, 4541, 13, 281, 897, 347, 247, 9551, 4968, 323, 253, 3110, 9739, 42317, 595, 1633, 326, 368, 812, 923, 4354, 275, 253, 3634, 273, 634, 1735, 4143, 13, 594, 368, 1053, 626, 452, 281, 564, 12203, 323, 352, 28, 651, 320, 9371, 604, 253, 2234, 1127, 369, 275, 271, 3477, 13, 1089, 494, 6308, 28, 309, 1871, 971, 247, 6010, 326, 1904, 626, 1379, 625, 685, 247, 5532, 281, 755 ]
75 African American20 Asian American10Degree MD84 NP21Half-day clinic sessions/week (average)4.8 sessions4.3 sessionsYears in practice (average)14.6 years14.4 yearsComfort with EHR Very comfortable72 Comfortable22 Uncomfortable11Likelihood to look for new ways to experiment with technology Always21 Sometimes42 Never42Comfort with computer usage overall Above average42 Average52 Below average11Comfort with medical practice change Very comfortable42 Comfortable11 Neutral41 Uncomfortable11 Design themes {#Sec8} ------------- Four themes emerged during the interview (see Table [2](#Tab2){ref-type="table"}), each is described in detail below.Table 2Design themes (*n* = 10 interviewees)ThemeDetailed idea (number of mentions)Barriers to establishing healthy lifestyles• Limited access to healthy food (6)\ • Limited access to exercise options (6)\ • Health literacy (6)\ • Multiple competing priorities (4)\ • Cost (5)\ • Lack of time to cook well, exercise (4)\ • Cooking and food storage facilities, homelessness (3)\ • Motivation (4)\ • Culture/family (2)Features of lifestyle modification program• In-clinic contact for warm handoff (8)\ • Community-based program (5)\ • Cultural, language sensitivity (4)\ • Economic sensitivity (2)\ • Education provided pictorially (2)\ • Physical activity facilitation -- pedometer (2)\ • Incentives to participate (2)\ • Integrate with PCP for synergy in messaging (3)\ • Social experience/support, peer network (1)\ • Help patient set small realistic goals (1)\ • Makes it easy to keep coming back (1)\ • Remote component -- phone/online (1)\ • Provide stress management/coping skills counseling (1)\ • Outcome/evidence based (1)\ • Scalable/few resources/automated in some way (1)\ • Identify patient and MD goals -- work toward mutual goals (1)Reporting of outcomes to primary care provider• Patient identified goals (5)\ • Patient's level of engagement (7)\ • Biometric data -- weight, blood pressure, hemoglobin A1c (6)\ • Patient's barriers, red flags that would make success near impossible (6)\ • Overall sense of progress (7)\ • How patient relates choices to health outcomes (1)\ • Food group breakdown versus fat/carbohydrate breakdown (2)\ • Patient's action plan (1)Integration with primary care• Quarterly updates (6)\ • Access and use in real-time with patients (7)\ • Provider alerts for new data (2)\ • Display in the EHR: graphical display, access coaching notes, patient goals and barriers (10)\ • Train ancillary staff to use data with patients (7)\ • Way to acknowledge receipt (1) ### Barriers to establishing healthy lifestyles {#Sec9} Among these safety-net primary care providers, there was almost uniform agreement that patients had multiple barriers to creating and sustaining healthy lifestyles. Limited access to healthy foods and walkable neighborhoods, low health literacy, and multiple competing priorities negatively impact a patient's ability to stay healthy regardless of their motivation."*"There's a systemic problem of food environment; we can do a little as primary care docs but it's a more systemic problem""Everybody can walk but people's neighborhoods aren't safe...people are afraid to walk in their neighborhoods sometimes; another challenge with our patients is affordability of healthy food and place to exercise and...depression; they have so much stress in their lives that food \[becomes the answer for their stress\]""Some of \[the barriers\] is \[sic\] health literacy; desire is there but they just don't understand what to do"*" Overcoming these barriers is complex, and often outside the realm of what seems possible through a primary care clinic."*"\[Patients\] need a lot of guidance and hand holding and it's hard to do that in a primary care visit""From a healthcare point of view, we're really not set up to do that whole process \[of counseling around lifestyle changes\]; this is a very medical model of care"*" ### Features of lifestyle modification program {#Sec10} All providers identified the desire to have some in-clinic contact with the patient to initiate the online diabetes prevention program. Providers believed that this would help motivate patients to join and stay active in such a program."*"Embedded here, would be wonderful, to have a nutritionist here on the floor to see patients before or after us \[doctors\]; help patients go more reliably""It's great we're doing population management, but it's still on us...We have to get them while they're here, if it was someone down the hall, it needs to be at the time of the visit to make the provider more efficient and to motivate the patient to do it and so the patient gets what they need at the time of the visit"*" Some providers wondered whether there could be a community-based aspect to the program; this would help patients stay engaged by being more culturally, socioeconomically, and geographically sensitive to patients' needs, and by allowing patients to share resources and ideas with each other."*"Most successful studies employed remote counseling; in-person arm didn't do any better than the remote arm because people don't show up for appointments; I think remote is key""Patients have resources and ideas that could be really helpful for other patients; like a buddy system or sharing in group visits"*" The importance of cultural and economic sensitivity was raised by many providers -- lifestyle programs are only successful if they can meet the patient where they are and make changes within certain confines."*"Culturally relevant cooking classes are a big resource we have""I dream of a walking group in all the relevant neighborhoods that had people who spoke the right languages"*" ### Reporting of program outcomes to the primary care provider {#Sec11} First and foremost, providers wanted to know the patient's goals in the program -- what were they and how were they developed. Knowing a patient's goals would help with motivational interviewing regardless of whether the patient was on track or had fallen behind in meeting their goals."*"Which goals were the patient working on; some sense of where the patient was at in terms of motivation and next steps"*" Providers identified the need for a sense of the patient's engagement with the diabetes prevention program; this information was deemed essential to determining the root cause of a patient's degree of success in meeting their goals."*"You can look at process or outcome; if they are participating and how often they're doing it and have we seen any results in their weight in general""The big issue is that so few of my patients are engaged in any way, I just want to know that they're engaged, someone is checking in on them, they're having progress forward"*" Providers also wanted a sense of the patient's barriers to success -- whether from coaching notes or from the patient themselves -- to explore these further with the patient and develop plans to overcome them. Providers genuinely wanted to support their patients in their efforts in healthy living; they saw this integration as a way to augment their inadequate mechanisms currently."*"I would love to know what's happening so when I see the patient I can reinforce, like a warm handoff from the program; would know we were giving consistent advice and weren't shooting each other in the foot""We know that \[patients\] trust \[in their providers\] improves some outcomes so maybe \[having the primary care provider more connected\] would, too"*" ### Integration with primary care {#Sec12} All providers thought that integrating external health-related data from between visits would help them better understand their patients and help their patients in disease prevention."*"My role \[as the primary care doctor\] is to get them to go to these programs, reinforce; for patients that don't need the whole package, I provide basics""I could seeing going to this \[the integrated data display\] rather than just the vital signs; looking at participation, how they're doing against their goals, and what the next steps are; it's more information than I have now"*" Many wanted quarterly updates on patients, but most importantly that the data be available to access and use in real-time with patients during clinic visits. Some identified the possibility of getting alerts when there was new activity from the patient in the system."*"As soon as you log in to the chart is there a way to know that the patient is in the program...because then I could see myself wanting to use it. I can see myself wanting to use the extra information to talk with the patient""Would be nice if it was in the EMR, would connect to the \[entire\] patient \[record\]""Quarterly would be plenty; I don't think we're going to see results so quickly"*" Providers wanted the data in the EHR with graphical, easy to interpret displays of the biometric data as well as access to the coaching notes and identified barriers."*"You see a goal -- they're green on weight, red on calories; easy to see quickly, to use as a teaching tool for the patient""Ideally something that you could see easily in the context of your next visit, so you don't have to go searching for it; would be helpful if the key point was in an easy, findable spot; I'd want a summary that didn't take more than a click to get
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next, which is we now have a galaxy that has seen this beacon of hope and is getting inspired to fight the good fight." 4. Kylo and Rey's connection is complicated for a reason The complicated relationship between Kylo Ren and Rey is one of the biggest strands of the film, for good reason. How does Johnson fall on how it affects them both? "To write these characters, I always have to get inside their heads. I tend to step inside and have the most generous reading of any character's motivation possible," says Johnson. "I'll say this – the moment when Kylo makes his appeal for her to join him, and Adam captured it so well in his little please, it was important to me that it wasn't a chess game, it wasn't just a manipulation. It's unhealthy, and there's much that is awful about the way that he is manipulative. From his point of view, it's a very naked, open, emotional appeal. It's his version of, 'I'm just a girl standing in front of a guy'... The same way as when he tells his version of the story with Luke, that's his experience of his moment. 5. Rey's parentage was a clear choice While there had been many theories about who Rey's parents might be – could she be a Skywalker? Related to Snoke - Johnson chose to go a very different route, choosing to label them, in Kylo Ren's words, "nobodies". Says the director, "I went through all the possibilities of who her parents could be. I made a list, with the upsides and downsides. There were two things about this option that made it feel right to me. Firstly. I like the idea that we're breaking out from the notion that the force is this genetic thing that you have to be tied to somebody to have. It's the 'anybody can be president' idea. Which I liked introducing. The foremost thing was just dramatically, storytelling-wise. The way I like to put it is, in The Empire Strikes Back, the big revelation is 'I am your father.' It's a big surprise, but I think the reason it lands is not because of that, but because it's the hardest possible thing that Luke, and hence the audience, could hear at that moment. You've had a bad guy that you can hate, that you can project your shadow on to cleanly, he's evil. It's simple. With that one line, suddenly that easy answer gets taken away from you, and he's something our protagonist has a relationship to and has to think in more complex terms, in terms of layers of redemption. For me, if Rey had gotten the answer that she's related to so-and-so, had learned her place in the story, that would be the easiest thing she can here. The hardest thing to hear is, 'nope, this not going to define you.' And in fact, Kylo is going to use this to try and undercut your confidence so you'll feel you have to lean on him for your identity. And you're going to have to make the choice to find your own identity in this story." 6. Carrie Fisher's death did not affect the story Fisher tragically died in between the film's shoot and its release, and, at time of writing, there are no plans to have her in the next movie, whether through unused material or digital trickery. Johnson faced some storytelling challenges around that. Did anything change to reflect the real-world events? "Nothing changed," confirms Johnson. "We discussed it briefly, and I spoke with Kathy (Kennedy, producer and Lucasfilm boss) when we came back after New Year's. We watched through her scenes and there was briefly talk of, 'god, do we adjust something so that we give her some kind of end in this movie?' I felt strongly that we shouldn't do that for a couple of reasons. We have a beautiful, complete performance from her, and that final moment is so powerful for her, and for us saying goodbye to her. And also, I can't imagine anything that we would be able to manufacture without having Carrie that would've been emotionally satisfying. I definitely I have no idea what would maintain that scene between her and Luke, or the scene in the Falcon. So we just decided to let it lie. I know JJ's going to come up with a way to resolve her in the next movie. 7. Holdo's hyperspace attack reaches back to a line from the past Laura Dern's Vice Admiral Holdo stages an audacious, devastating attack on the First Order's ships in a massively dramatic moment from the movie. It was important for Johnson to get in. "I'm sure that a lot of fans had thought ever since Han was talking about if you don't get the calculations right you could go through a star...," Johnson explains. "I always wanted to see what that would look like, and at some point, one of the guys at ILM hit upon that exposure idea of everything going silent. We were struggling with how do we make this visually impressive and when we hit on that, we loved it. 8. Snoke's unceremonious death allowed for a new paradigm Johnson has previously told Empire that he's not particularly interested in where Snoke comes from, and he dispatches the villain in The Last Jedi. What was behind that thinking? "I like Snoke as a character as Andy (Serkis) plays him," the director clarifies. "He's delicious, evil and fun. But Kylo to me is where the interesting stuff is. And the notion of clearing the deck of the Vader/Emperor dynamic so that all bets are off in terms of how the villainy is going to play out, that to me seemed like a much more interesting thing. And it just seemed natural. If he had stopped in the middle of a scene and given a monologue, it would've stopped it dead in its tracks, and we would've cut it out in the editing room. This is not Snoke's story. 9. Luke and co.'s expanded Force powers had to compete with what we've seen before The likes of Leia, Luke and Snoke all display incredible Force powers in the film. Johnson acknowledges that this was something he wanted to tackle. "It was twofold," Johnson explains. "First of all, it's tough, because at this point between The Force Awakens and even the video games, the level of Force powers has slowly come up. I feel like we still offered a modicum of restraint, because we didn't have anyone pulling Star Destroyers out of the sky. And believe me, it came up when Luke came out on to the field, I was, like,'should he wave his hand and all the walkers blow off like dust?' The things that are in there that are Force moments largely came out of the dramatic moments. But the Leia thing is an interesting example. It's something that Kathy kept bringing up, which I thought was interesting. She said, 'I've always been intrigued by what Luke says to Leia in Jedi in that she has the power inside her also, and why haven't we seen that?' And the idea behind Leia's big moment was that it was not incredibly powerful, because she's in space and that doesn't offer much resistance, it doesn't take much to pull her back in. But also, that it's instinctual. It's like when you hear parents that have a toddler trapped under a car, and they lift the car up with Hulk strength. The idea that it's not going to end today, that she's not finished yet." 10. Johnson had to resist being a fanboy around Adrian Edmondson The comedy legend has a cameo as a First Order officer. So how exactly did Eddie Hitler end up joining the fray? "I had been a huge fan of The Young Ones when I was in high school, and Bottom, I was an even bigger fan of. I thought it was the funniest thing in the world, and actually filmed the opening scene of the Bottom pilot for a student film. When I was out of film school, I shot a 16mmm version of it with my friends," admits Johnson. "The whole time he was on set, I was just trying to play it cool." Edmondson brought his own energy to the movie. "If you just keep your eyes on him during any scene he's in, it's an entirely different movie, because he's always doing some kind of eye roll..."Claire Bernish February 2, 2016 (ANTIMEDIA) If you’ve ever been told your vote doesn’t count, but didn’t quite believe that to be true — maybe you were raised to believe in the power of democracy, or perhaps you feel your vote might prevent that other guy from grabbing the highest seat of power in the land — the Federal Election Commission filings released on Sunday should prove the obstacles of cash your vote faces at the polls. Much ado has been made about campaign contributions, particularly since the Supreme Court handed down its decision in Citizens United v. FEC in January 2010. That ruling essentially deemed corporations ‘people’ whose spending — whether to support or denounce individual candidates — amounts to political speech. As a result, the court decided, their speech is protected by the First Amendment. Many wondered what would happen to the already convoluted power of an individual’s vote in the face of mountains of virtually endless campaign advertising and strategy spending — and exactly how much money would the ‘new people’ and their billionaire backers spend.
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results provided substantive answers to the agency's concerns as well as methodological guidelines for future evaluations of community awareness.Filed 12/26/13 P. v. Cianci CA1/1 NOT TO BE PUBLISHED IN OFFICIAL REPORTS California Rules of Court, rule 8.1115(a), prohibits courts and parties from citing or relying on opinions not certified for publication or ordered published, except as specified by rule 8.1115(b). This opinion has not been certified for publication or ordered published for purposes of rule 8.1115. IN THE COURT OF APPEAL OF THE STATE OF CALIFORNIA FIRST APPELLATE DISTRICT DIVISION ONE THE PEOPLE, Plaintiff and Respondent, A138854 v. ALLAN JOSEPH CIANCI, (San Mateo County Super. Ct. No. SC076123A) Defendant and Appellant. In this case, defendant Allan Joseph Cianci entered no contest pleas to an information filed by the San Mateo County District Attorney. His appellate counsel has made an independent review of the proceedings below and concluded the record reflects no meritorious claims for an appeal. He has advised defendant of his conclusion and advised Cianci he may file supplemental papers raising issues he believes merit appellate review. Cianci has not filed any such pleadings. Pursuant to People v. Kelly (2006) 40 Cal.4th 106, 119, and People v. Wende (1979) 25 Cal.3d 436, counsel asks this court to conduct an independent review of the record. We have done this review and find no issues meriting further appellate consideration. STATEMENT OF THE CASE In an information filed on July 23, 2012, defendant was charged with possession of a controlled substance in violation of Health and Safety Code section 11377, subdivision (a) (count 1); misdemeanor use of force or violence on a peace officer in violation of Penal Code section 243, subdivision (b) (count 2); two counts of misdemeanor resisting or obstructing a police officer in violation of Penal Code section 148, subdivision (a)(1) (counts 3 and 4); two misdemeanor counts of possession of controlled substance paraphernalia in violation of Health and Safety Code section 11364.1 (counts 5 and 7); and possession for sale of a controlled substance (methamphetamine) in violation of Health and Safety Code section 11378 (count 6). Regarding count 6, the information alleged four prior felony convictions within the meaning of Penal Code section 1203, subdivision (e)(4); two prior prison terms within the meaning of Penal Code section 667.5, subdivision (b); and one prior serious or violent felony conviction within the meaning of Penal Code section 1170.12, subdivision (c)(1). At his arraignment on July 25, 2012, defendant pled not guilty, and denied all allegations and priors. On February 13, 2013, defendant moved to dismiss count 6 on the grounds of multiple prosecutions under the Fifth Amendment of the United States Constitution and article I, section 15 of the California Constitution, Penal Code section 654, and Kellett v. Superior Court (1966) 63 Cal.2d 822. The trial court denied the motion to dismiss on March 5, 2013. Defendant withdrew his not guilty pleas on March 19, 2013. He entered no contest pleas to count 3, a violation of Penal Code section 148, subdivision (a)(1), and count 6, a violation of Health and Safety Code section 11378. As part of the bargain, defendant admitted as part of count 6 one prior serious or violent felony conviction within the meaning of Penal Code section 1170.12, subdivision (c)(1). For his pleas, a promise was made the maximum sentence of up to 32 months in state prison would be imposed. All remaining counts, allegations, and enhancements would be dismissed. Furthermore, the trial court would entertain a motion to dismiss the prior allegation under People v. Superior Court (Romero) (1996) 13 Cal.4th 497 (Romero). Both orally on the record, and in his written plea form, defendant specifically waived his constitutional 2 rights under Boykin-Tahl.1 Trial counsel agreed with the waiver of rights and stipulated there was a factual basis for the no contest pleas. On April 30, 2013, defendant made his motion pursuant to Romero. The prior felony was assault with a deadly weapon, a violation of Penal Code section 245, subdivision (a)(1) in the County of San Mateo in 2006. The trial court denied the Romero motion on May 14, 2013. The trial judge denied probation and sentenced defendant to the mitigated term of 16 months on count 6. The sentence was doubled to 32 months pursuant to Penal Code section 1170.12, subdivision (c)(1). The court also sentenced defendant to a concurrent sentence of 30 days for his no contest plea to count 3. Additionally, the court imposed certain fines and other statutory conditions based on the convictions here. Defendant filed a timely notice of appeal on May 31, 2013. The appeal is from a final judgment after a no contest plea and is based on the sentence. (Pen. Code, § 1237; Cal. Rules of Court, rule 8.304(b)(4)(B).) STATEMENT OF FACTS A. Misdemeanor Resisting an Officer (Count 3) On April 6, 2012 at 10:50 p.m., Daly City Police Officer William Tone stopped defendant on Skyline Boulevard in San Mateo County for speeding and because the license plate on defendant’s motorcycle was not illuminated. Defendant advised the officer, when questioned regarding his nervousness, that he had two ounces of marijuana in his backpack. After a consent search, the drugs were found. During the stop, defendant resisted and pushed Officer Tone into his patrol vehicle, and hit him in the mouth. Eventually, the men struggled on the ground. After additional officers arrived Defendant was subdued and cuffed. 1 Boykin v. Alabama (1969) 395 U.S. 238 (Boykin); In re Tahl (1969) 1 Cal.3d 122 (Tahl). 3 B. Possession of Methamphetamine for Sale (Count 6) On April 13, 2012, California Highway Patrol Officer Salaun made a traffic stop for speeding on Highway 280 in San Bruno, California. Defendant was driving the car. He was also cited for driving without a license, no proof of insurance, and invalid transfer of vehicle registration. While the initial citation process was being conducted, a passing citizen advised the officer defendant had tossed something onto the shoulder of the road before Salaun stopped his car. Officer Salaun checked the area initially but found no items. After citing and releasing defendant, the officer looked further. He found a pouch where the citizen had pointed. It contained a scale, plastic baggies, a bag of marijuana and a bag of methamphetamine. This pouch was confirmed by the citizen as the object tossed by defendant. The bag contained 21.21 grams of methamphetamine. DISCUSSION We have reviewed the record here. Defendant was properly advised of his rights before entering the no contest pleas. The facts support each of the two pleas. The trial court exercised its discretion in denying defendant’s Romero motion. We affirm the judgment. 4 _________________________ Dondero, J. We concur: _________________________ Margulies, Acting P.J. _________________________ Becton, J.* * Judge of the Contra Costa County Superior Court, assigned by the Chief Justice pursuant to article VI, section 6 of the California Constitution. 5 Overview Get to know Malaysia in one of the most satisfying ways – on a food-tasting tour! With an enthusiastic guide, drop in to three or more hole-in-the-wall restaurants and food stalls at a Kuala Lumpur hawker center or off-the-beaten-track neighborhood that features the best of Malaysian cuisine. As you enjoy the delicious food and meet friendly locals, your guide will ensure you have an epicurean adventure that can’t be beat. All food tastings – no matter how much food you eat – are included, so come hungry! After meeting your guide at a central Kuala Lumpur location, easily accessible by the city’s Light Rail Transit, your small-group food tour begins as you board an air-conditioned vehicle for the drive to the KL neighborhood of your guide’s choice (the neighborhood(s) you visit are up to your expert guide and will vary based on the day of the week). One such neighborhood you may visit is the Bangsar area, which boasts a wide array of food spots like mamak stalls serving traditional Tamil-Muslim cuisine, South Indian banana-leaf restaurants serving delectable treats on a banana leaf, and Malay warungs (small family-owned establishments serving both local and Western snacks). Or, you might head to Petaling Jaya, where you’ll visit a ‘round-the-clock hawker center (open-air
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the preface to book 1 (1.1–12) his arguments are quite general, even where their Roman applications are obvious enough and sometimes explicitly articulated. 6 I shall be referring to Sallust's discussion of the contrasting virtues of Caesar and Cato in chapter 54 of his _Catilina_ below (p. 205): reflective and pointed, if not theorized. 7 See the suggestions for further reading. 8 On Cato's Stoicism and his suicide see M. Griffin 1986. 9 Tyranny is how Cicero habitually thinks of Caesar's rule, on occasion even to the point of using the Greek expression _turannos,_ whether neat, as privately in correspondence with Atticus in March 49 ( _Att._ 9.13.4), or in transliteration, as publicly in 44 after Caesar's assassination ( _Off._ 3.19). But others spoke of Caesar differently. Sallust, for example, speaks not of the concentration of power in the hands of one man (Cic. _Div._ 2.6), but says of him that he sought for himself _imperium, exercitum, bellum novom_ so that his _virtus_ could shine forth (not that Cicero would have disagreed with that: cf. e.g. _Off._ 1.26) -reflecting Caesar's own claim that in crossing the Rubicon what he was defending above all was his own _dignitas (B Civ._ 1.9.2; cf. Cic. _Att._ 7.11.1). Caesarians would speak of his _lenitas_ and _dementia_ in victory ( _B Afr._ 86, 92), although Caesar himself- writing again in March 49 – preferred words like _misericordia_ and _liberalitas_ (Cic. _Att._ 9.7C; echoed in Sallust's talk of his _beneficia_ and _munificentia,_ his _mansuetudo_ and _misericordia:_ Sall. _Cat._ 54.2), no doubt because they sounded less monarchical than _clementia._ In this connection the brilliant discussion of "political catchwords" in Syme 1939: ch. 11 is still well worth consulting; on the political subtleties of the vocabulary of mercy at Rome during the civil war and its aftermath see Griffin 2003, Benferhat 2005: chs 4 and 5. 10 On Cicero's economy with the truth in the story he liked to tell of the circumstances of his exile, see Robert Kaster's analysis in this volume, chapter 20. 11 See further Schofield forthcoming. 12 A phrase repeated e.g. at _Fin._ 2.100. 13 For the Stoic credentials of _magnus et excelsus homo_ he cited the account of Stoic ethics in Stobaeus: "The virtuous person is big and powerful and tall and strong" ( _Ed._ 2.99.12–14; these seemingly physical attributes are then all explained in terms of moral psychology in the sequel: 2.99.14–19). 14 See e.g. Schofield 2002a. 15 He pretends at this point in the speech that his audience are all of them _cognoscenti (Mur._ 61 _ad init.)._ 16 For more on _Pro Sestio_ see Robert Kaster's discussion in chapter 20. 17 These virtues are coupled as qualities Cicero salutes (along with _gravitas)_ in the proconsular P. Lentulus, in a letter to him of February 56 ( _Fam._ 1.5a.4); and he accords them to his friend Trebonius, in a letter to him of June 45 ( _Fam._ 6.11.2), in connection with his _dignitas._ At _Fin._ 3.25 (also 45), in Cicero's exposition of Stoic ethics, _magnitudo animi_ is actually identified along with _iustitia_ as a form of _sapientia,_ characterized by judging that everything that can happen to a human being is beneath notice. 18 On the fourth virtue see Schofield forthcoming. 19 See the references at note 9 above. 20 How would such behaviour exemplify "contempt for things human" (1. 13, 67, 72)r Cicero's discussion (1.72–3) suggests that great spirits are free from worry about what will happen to them or about what resources they have in life. In other words, they despise not human life itself, but the preoccupations which usually dominate people's minds. Unlike other men, they "appreciate the frailty of things human and the variability of fortune," as Panaetius is quoted as saying, and are unimpressed by them (1.90). 21 On _felicitas –_ and Caesar's luck in particular – see Murphy 1985–6. 22 Gildenhard 2007: 122 n100 (here using a phrase in Dyck 1998: 228, of which he says: "it is hard to find a more appropriate characterization of Cato's attitude to life under Caesar"). 23 On cl _ementia_ see M. Griffin 2003. # CHAPTER 14 # Roman Democracy? _W. Jeffrey Tatum_ The Roman constitution, never comprehensively codified, resided in the Romans' accumulation of customary practices, traditional regulations, and public legislation. The result was a system of government that remained complicated and untidy (see Hammer, this volume, chapter 2). Polybius, in the earliest analysis of the Roman constitution known to us, concentrated his attention on what he perceived to be the three principal elements of Rome's government – the magistrates, the senate, and the people – all of which combined, in their mutual competition, to yield what he deemed to be a mixed constitution (Polyb. 6.11–18). Greek political theory recognized three fundamental kinds of constitution: government by one, by a few, and by the many, the manifestations of which could be either attractive (in which case one had to do with monarchy, aristocracy, or democracy) or the opposite (thus furnishing tyranny, oligarchy, or ochlocracy). More complicated states were viewed as conglomerations of these basic bits, resulting, for instance, in Aristotle's complicated discussions of constitutional compounds that required careful scrutiny before one could determine whether they were, in the end, more like a democracy or more like an aristocracy (Arist. _Pol._ 2.1266a26–8; 4.1294bl3–16, 34–6; cf. Rowe 2000b: 384–7). A mixed constitution was one that successfully joined the virtues of monarchical, aristocratic, and popular government in order to create a stable and just state. This view was already ancient when Polybius brought it to bear on Rome (Walbank 2002: 281), where it found the consuls exercising a limited version of regal power, the senate, composed of Rome's wealthiest men, supervising Roman finances, the management of Italy and the conduct of Roman foreign policy, and, in the power of the popular assemblies to dispense honor and punishment, to accept or to reject laws and to decide questions of war and peace, Rome's democratic dimension. Roman stability, in Polybius' assessment, was owing to the checks each element put on the superiority of any other: a consul at war, for example, because he required the cooperation of the senate and the people if he hoped to secure victory and glory, could not be indifferent to their wishes. This was not to say that the balance was in every way even: Polybius observes that the superiority of the Roman to the Carthaginian constitution (another mixed constitution) at the time of the Hannibalic War was an effect of the latter's greater inclination toward democracy than to aristocracy (Polyb. 6.51; see Hahm, this volume, chapter 12). Polybius was aware that his account of the Roman constitution was incomplete and reductive (Polyb. 11.3–8). It did not occur to him, however, to inquire whether Greek political theory furnished the best means for understanding the complications of Roman government. One might without unfairness attribute his conclusions to the simple coincidence that (i) in Polybius' opinion, Rome enjoyed a superlative constitution, and (ii) as every Greek intellectual was aware, a superlative constitution must be a mixed constitution. Consequently it was merely left to Polybius to discover in the actualities of Roman government what he knew had to be there in the first place: monarchical, aristocratic, and democratic institutions (Seager forthcoming). This train of thought might, for instance, help to explain his failure to observe that Roman consuls were all of them senators before their elevation to high office and all of them senators once more at the completion of their magistracy, a reality that tended to narrow the gap between those two elements of the constitution in contrast to the distance between the many who constituted the people and the few who inhabited the senate and the magistracies (Hölkeskamp 2004: 266–7; cf. the approaches outlined by Hahm, chapter 12). Nor, as we shall see, is the democratic quality of the popular assemblies entirely incontestable or unqualified. It has in fact been objected that Greek categories are entirely useless and even misleading concepts for understanding Roman society, the dynamics of which must be understood on their own terms (Meier 1980: 45–63; Flaig 1995: 88–9; Hölkes
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The Sambodromo today is also known as the Sambadrome Marquês de Sapucaí and has earned its place in the Carnival history. Nearly a million tourists each year cluster in Rio not just to watch the spectacle but also to experience that unique Afro-European culture in Brazil. The event at the Sambadrome has become very popular that major TV channels around the globe send their own crew to tape the Carnival for the worldwide audience. There is a price of admission, however, since each spot to the Sambadrome is highly sought. But you can always watch for free the many performances or the rehearsals of the top schools prior to the culminating parade. Computing the Carnival Period It’s quite easy to determine the date of the Carnival. You only have to look at the Carnival history to gain a perspective of why. The carnival is observed from Friday until the day preceding Ash Wednesday. So you can understand the term Fat Tuesday. The dates obviously change every year depending on the calendar. Ramon Moreira | Bookers International According to formula decided by the Council of Nicea in 325 AD, Easter should fall between March 22 and April 25 as determined by the Paschal full moon. Of course, it’s ridiculous to think that the original aim of the carnival when the Catholic Church adopted it was for devotees to have five days of extravagance and self-indulgence. The Church might balk at the garish spectacle but economics play a huge part in the modern extravaganza. The original purpose, as can be learned from the Carnival history, was for Christians to celebrate before subjecting themselves to a 40-day of sacrifice until Easter./* Generated by Font Squirrel (http://www.fontsquirrel.com) on June 14, 2013 02:25:19 PM America/New_York */ @font-face { font-family: 'Ubuntu'; src: url('Ubuntu-L-webfont.woff') format('woff'), url('Ubuntu-L-webfont.ttf') format('truetype'); font-weight: normal; font-style: normal; } @font-face { font-family: 'UbuntuItalic'; src: url('Ubuntu-RI-webfont.woff') format('woff'), url('Ubuntu-RI-webfont.ttf') format('truetype'); font-weight: normal; font-style: normal; } @font-face { font-family: 'UbuntuBold'; src: url('Ubuntu-B-webfont.woff') format('woff'), url('Ubuntu-B-webfont.ttf') format('truetype'); font-weight: normal; font-style: normal; } @font-face { font-family: 'UbuntuBoldItalic'; src: url('Ubuntu-BI-webfont.woff') format('woff'), url('Ubuntu-BI-webfont.ttf') format('truetype'); font-weight: normal; font-style: normal; } @font-face { font-family: 'UbuntuLight'; src: url('Ubuntu-L-webfont.woff') format('woff'), url('Ubuntu-L-webfont.ttf') format('truetype'); font-weight: normal; font-style: normal; } @font-face { font-family: 'UbuntuLightItalic'; src: url('Ubuntu-LI-webfont.woff') format('woff'), url('Ubuntu-LI-webfont.ttf') format('truetype'); font-weight: normal; font-style: normal; } @font-face { font-family: 'UbuntuMedium'; src: url('Ubuntu-M-webfont.woff') format('woff'), url('Ubuntu-M-webfont.ttf') format('truetype'); font-weight: normal; font-style: normal; } @font-face { font-family: 'UbuntuMediumItalic'; src: url('Ubuntu-MI-webfont.woff') format('woff'), url('Ubuntu-MI-webfont.ttf') format('truetype'); font-weight: normal; font-style: normal; } @font-face { font-family: 'UbuntuCondensedRegular'; src: url('Ubuntu-C-webfont.woff') format('woff'), url('Ubuntu-C-webfont.ttf') format('truetype'); font-weight: normal; font-style: normal; } RALEIGH (October 19, 2012) – Public sector layoffs erased private sector job gains in September, according to new unemployment numbers released by the Division of Employment Security today. These layoffs are largely responsible for the stubbornly high unemployment rate, which showed a negligible decrease from a summer high of 9.7% in August to 9.6% last month. While this improvement is certainly a positive sign, the state has failed to create enough total jobs to reduce unemployment to where it was in April, May, and June, when the jobless rate clocked in at 9.4%. Part of the problem is the sluggish rate of private sector job growth, coupled with the long-term erosion of government employment. Although North Carolina experienced private sector job growth last month with the creation of 1,500 new jobs (seasonally adjusted), these gains were almost completely wiped out by the 1,400 reduction in public sector employees — 98% of which came from state government. Looking at government employment over the last year, we see a similar trend. Without the 5,500 public sector layoffs experienced in the last 12 months, the number of total nonfarm jobs created in North Carolina since September 2012 would have been 17% higher, and the state’s unemployment rate would have been 9.4% — unchanged from the jobless rate in April, May, and June. “While the new report certainly demonstrates a small measure of progress, we shouldn’t start celebrating yet, since we haven’t yet reclaimed the ground lost over the summer. A big part of this story is the continuing layoffs of public sector employeesin the middle of an already challenging economic recovery,” said Allan Freyer, Public Policy Analyst with the Budget Tax Center, a project of the NC Justice Center. “Just as with private sector layoffs, government layoffs increase the number of people out of work. Given that there are already nearly three times as many people looking for work than there are job openings, these public sector layoffs only serve to increase overall unemployment.”This dude trains Hailey learn how to treat a stick and nut sack, nevertheless it has nothing to do with the sport of pool they’re taking part in. She grabs the stick inbetween his gams, which is getting stiffer by the 2nd on the look of her flawlessly perky tits and candy, slick coochie. She marvels on the thickness of his beef whistle and drinks it down until she gags. Nonetheless standing and with one foot up on the pool desk, she slips her coochie on his dick. Hailey is petite and lightweight, the ideal dimension to choose up and fuck within the air, which is what this dude does. Then they budge to the sofa for extra constant fucking, the place Hailey cums throughout his beef whistle till her eyes roll again and her assets yanks. You may inform she genuinely likes to get pounded and glazed. Too unhealthy not all pool video games finish like this.Get a Commemorative Person of the Year Polo Shirt! Get this commemorative Polo Shirt from our 2017 POY Golf Outing for Jim Tressel and re-live the magic all over again! This outing was amazing and now you can get your hands on this limited edition Polo Shirt and be the talk of the office all year!! Limited sizes and quantities are available and once they are gone, they are gone! Wow. A week ago, over 150 golfers and members converged on Medallion Club in Westerville for one of the nicest Spring days of the year for our annual 18 hole scramble. We had a fantastic day with not only Coach Tressel and Coach Connolly in attendance, but the likes of Craig Krenzel and AJ Hawk running around the course made the day a good time for all. We were also joined by our very own weekly luncheon and emcee 10TV's Dave Maetzold, the Voice of OSU Football Mr. Paul Keels, and OSU Historian Jack Park all had their hands in making this one special day for all! We raised a LOT of money for plaques, awards and scholarships and everyone was treated to a fantastic Steak dinner after a great day on the links. Tressel announced 2017 Agonis Person of Year Please join The Agonis Club of Columbus, its proud members