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cc956756-d615-50b1-baf9-5bcd745c1821 | 4 | C | 1 | What is the onset of action for Morphine? | 2 hours | 30-60 seconds | 15-30 minutes | 5-10 minutes | 吗啡的起效时间是多久？ | 2小时 | 30-60秒 | 15-30分钟 | 5-10分钟 | null | null | null | null | null | null | null | null | null | null |
550a41ef-c4ec-5982-ba46-d99717a70c23 | 4 | B | 1 | Which of the following effects is NOT associated with morphine. | Facial Redness | Stop Shivering | Hypotension | All of the above | 以下哪种效果与吗啡无关。 | 面部潮红 | 停止发抖 | 低血压 | 以上皆是 | null | null | null | null | null | null | null | null | null | null |
96d1fbf1-1ce3-5831-ab9b-d3ebbf451d73 | 4 | C | 1 | Which of the opioids will NOT cause miosis? | Morphine | Fentanyl | Meperidine | Narcan | 哪种阿片类药物不会引起瞳孔缩小？ | 吗啡 | 芬太尼 | 哌替啶 | 纳洛酮 | null | null | null | null | null | null | null | null | null | null |
b39f27f1-7405-5227-bf8c-a5cd5e405003 | 4 | C | 1 | Which opioid has the highest degree of lipid solubility? | Sufentanil | Remifentanil | Fentanyl | Morphine | 哪种阿片类药物具有最高的脂溶性？ | 舒芬太尼 | 瑞芬太尼 | 芬太尼 | 吗啡 | null | null | null | null | null | null | null | null | null | null |
568deac3-febe-5b30-a319-a83117511fcd | 4 | D | 3 | You are caring for Mrs. Tica who has a past history of A-fib, DM, pancreatitis & asthma. Which drug would you choose to relieve her pain? | Toradol | Morphine | Ethanol | Fentanyl | 您正在照顾有房颤、糖尿病、胰腺炎和哮喘病史的Tica女士。您会选择哪种药物来缓解她的疼痛？ | 托拉多尔 | 吗啡 | 乙醇 | 芬太尼 | null | null | null | null | null | null | null | null | null | null |
7c8ad3dd-3f5c-5741-998f-30d78eed62b9 | 4 | C | 1 | Why is remifentanil unique among the opioids? | Can be safely given to asthmatics and those on MAOI's | Does not cause miosis | Context sensitive half time independent of infusion time. | Most rapid onset with large Vd. | 为什么瑞芬太尼在阿片类药物中是独特的？ | 可以安全地给哮喘患者和服用单胺氧化酶抑制剂的人使用 | 不会引起瞳孔缩小 | 上下文敏感半衰期与输注时间无关。 | 起效最快，分布容积大。 | null | null | null | null | null | null | null | null | null | null |
1d6b1166-5636-5e26-bee4-4b2eee990063 | 4 | A | 1 | Fentanyl has a much more rapid onset but a longer elimination half time than Morphine. Why? | Because of fentanyl high lipid solubility | Because fentanyl is highly protein bound | Because Morphine has a much high lipid solubility and thus is excreted more rapidly | Because morphine has a much larger Vd. | 芬太尼的起效更快，但消除半衰期比吗啡长。为什么？ | 因为芬太尼的高脂溶性 | 因为芬太尼高度蛋白结合 | 因为吗啡具有更高的脂溶性，因此排泄更快 | 因为吗啡具有更大的分布容积 | null | null | null | null | null | null | null | null | null | null |
59b3690b-7c69-5c64-a46b-52c55f029abb | 4 | C | 2 | Which medication would you give to reliev post-op itching caused by Morphine? | Narcan 1-4 mcg/kg IV | Flumazenil, titrate by doses of 0.2 mg | Nubain 10-20 mg IV | Meperidine | 您会给予哪种药物来缓解由吗啡引起的术后瘙痒？ | 纳洛酮 1-4 mcg/kg 静脉注射 | 氟马西尼，按 0.2 mg 剂量滴定 | 纳布啡 10-20 mg 静脉注射 | 哌替啶 | null | null | null | null | null | null | null | null | null | null |
9114db64-e294-5b5b-9abf-12cb74148b90 | 4 | C | 1 | Which of the following benzodiazepines is most commonly used during the preoperative period and for IV conscious sedation? | Diazepam | Lorazepam | Midazolam | Alprazolam | 以下哪种苯二氮䓬类药物最常用于术前期和静脉镇静？ | 地西泮 | 劳拉西泮 | 咪达唑仑 | 阿普唑仑 | null | null | null | null | null | null | null | null | null | null |
3821c09a-0648-5ebe-a01b-362ecfb1c82c | 4 | A | 1 | Which adverse reaction is a patient most likely to experience after receiving general anesthesia? | Nauseau & Vomiting | Seizures | Cyanosis | Increased HR | 患者在接受全身麻醉后最有可能出现哪种不良反应？ | 恶心和呕吐 | 癫痫发作 | 发绀 | 心率增加 | null | null | null | null | null | null | null | null | null | null |
6d87489e-0f64-57fb-889e-42f24df8ad8a | 4 | C | 1 | What is responsible for the pain reaction elicited when diazepam is given IM? | Any IM injection is painful | Ethyl alcohol component | Propylene glycol component | Solubility component | 当地西泮以肌肉注射方式给药时，是什么引起了疼痛反应？ | 任何肌肉注射都会疼痛 | 乙醇成分 | 丙二醇成分 | 溶解性成分 | null | null | null | null | null | null | null | null | null | null |
8473d9d5-042f-5114-a363-18c3254e80f7 | 5 | C | 1 | Which of the following is not one of the Five Principle pharmacological effects of Benzodiazepines? | Sedation | Anxiolysis | Retrograde Amnesia | Anticonvulsant | 以下哪一项不是苯二氮卓类药物的五大药理作用之一？ | 镇静 | 抗焦虑 | 逆行性遗忘 | 抗惊厥 | Spinal Cord mediated skeletal muscle relaxation | 脊髓介导的骨骼肌松弛 | null | null | null | null | null | null | null | null |
773f100d-92cf-5148-9d9f-7db08f66a71f | 4 | B | 2 | While doing a pre-op assessment on an inpatient you find that the pt is currently taking Tagamet (cimetidine) and is on a Heparin regimen. With this knowledge you know to avoid which of the benzodiazepines? | Lorazepam | Diazepam | Midazolam | Thiopental | 在对住院病人进行术前评估时，你发现病人目前正在服用Tagamet（西咪替丁）并正在接受肝素治疗。基于此信息，你知道应该避免使用哪种苯二氮䓬类药物？ | 劳拉西泮 | 地西泮 | 咪达唑仑 | 硫喷妥钠 | null | null | null | null | null | null | null | null | null | null |
5015fb3b-f571-5df3-982f-815c8ca71784 | 4 | B | 2 | In regards to the adjustments of Benzodiazepines in respect to the elderly patient. Would you expect to have: | Significant increase in initial dose and anticipate marked decrease in duration of action | Modest decrease in initial dose and anticipate marked increase in duration of action | No change in dose or frequency or duration from that of an healthy 25 year old patient. | None of above | 关于苯二氮卓类药物在老年患者中的调整，您会预期： | 初始剂量显著增加，并预期作用持续时间显著减少 | 初始剂量略微减少，并预期作用持续时间显著增加 | 剂量、频率或持续时间与健康的25岁患者无变化。 | 以上都不是 | null | null | null | null | null | null | null | null | null | null |
e8bca84d-bb57-50b0-a895-8a47ad7ca930 | 2 | B | 1 | The dose of Benzodiazepines required to reach a desired clinical end point is increased in the elderly compared to the younger patient. | True | False | null | null | 与年轻患者相比，老年患者达到预期临床终点所需的苯二氮卓类药物剂量增加。 | 正确 | 错误 | null | null | null | null | null | null | null | null | null | null | null | null |
91f7b8e1-a099-5779-8339-fb4db0dc90cf | 3 | B | 2 | Benzodiazepines are extensively protein bound. Therefore, in the presence of renal failure their clinical effect will be: | Shortened | Prolonged | No significant change. | null | 苯二氮䓬类药物广泛结合蛋白质。因此，在肾功能衰竭的情况下，其临床效果将是： | 缩短 | 延长 | 无显著变化。 | null | null | null | null | null | null | null | null | null | null | null |
9aa91ec0-5546-5e47-be41-0d2f736c5e85 | 4 | D | 1 | A drug that alters the physiology of a cell by binding to the plasma membrane or intracellular receptors is known as what? | Antagonist | Competitive Agonist | Competitive Antagonist | Agonist | 通过与质膜或细胞内受体结合来改变细胞生理的药物被称为什么？ | 拮抗剂 | 竞争性激动剂 | 竞争性拮抗剂 | 激动剂 | null | null | null | null | null | null | null | null | null | null |
7f87ba2e-3a41-54ec-9e52-2d128a069d85 | 4 | A | 1 | What is an antagonist? | Inhibit or block responses caused by an agonist | A drug which alters the physiology of a cell by binding to plasma membrane or intracellular receptors | Biochemical messengers, often called 2ndmessengers | The strength of binding between drug and receptor | 什么是拮抗剂？ | 抑制或阻断由激动剂引起的反应 | 通过与质膜或细胞内受体结合来改变细胞生理的药物 | 生化信使，通常称为第二信使 | 药物与受体之间结合的强度 | null | null | null | null | null | null | null | null | null | null |
0ab33f4d-bf06-540e-9910-58879406e5e7 | 4 | D | 1 | What is the MOA of Benzos? | Blockade of chloride channels leading to depolarization and inhibition of neurotransmitter | Inhibition of cyclooxygenase activity | Inhibition of GABA receptor binding which leads to degredation of GABA, preventing it from exerting it's effect. | Enhances the inhibitory effects of various neurotransmitter by facilitating GABA receptor binding. This opens chloride channels and causes hyperpolarization. | 苯二氮卓类药物的作用机制是什么？ | 阻断氯离子通道导致去极化和神经递质的抑制 | 抑制环氧合酶活性 | 抑制GABA受体结合，导致GABA降解，阻止其发挥作用。 | 通过促进GABA受体结合增强各种神经递质的抑制作用。这会打开氯离子通道并导致超极化。 | null | null | null | null | null | null | null | null | null | null |
357a17e4-443e-5b3a-b277-41b6ef9b1d55 | 4 | B | 1 | All benzos share what similarities? | All are highly alkaline solutions | Composed of a benzene ring fused to a seven-membered diazepine ring | They are safe to be given during pregnancy | Composed of malonic acid and urea | 所有苯二氮卓类药物有什么相似之处？ | 都是高度碱性溶液 | 由苯环与七元二氮杂环融合而成 | 在怀孕期间使用是安全的 | 由丙二酸和尿素组成 | null | null | null | null | null | null | null | null | null | null |
89f05e21-88ce-59e5-afe9-e42a81706922 | 4 | C | 1 | How is midazolam unique in comparison to other benzos? | It is the only benzo safe to give to pregnant women. | Is known to cause pain upon injection, but has minimal respiratory depression | It is hydrophilic and becomes lipid soluble upon exposure to blood. | It is not highly protein bound like the other benzo's and thus more is available for use by the body. | 与其他苯二氮卓类药物相比，咪达唑仑有何独特之处？ | 它是唯一一种可以安全用于孕妇的苯二氮卓类药物。 | 已知会引起注射时疼痛，但呼吸抑制作用最小。 | 它是亲水性的，暴露于血液后变为脂溶性。 | 它不像其他苯二氮卓类药物那样高度蛋白结合，因此更多可供身体使用。 | null | null | null | null | null | null | null | null | null | null |
36d134d4-cf0b-5371-83b9-6af036a8e57e | 4 | D | 1 | Which of the following drugs will cause pain upon injection due to the solvent propylene glycol? | Lorazepam | Flumazenil | Midazolam | Diazepam | 以下哪种药物由于溶剂丙二醇会在注射时引起疼痛？ | 劳拉西泮 | 氟马西尼 | 咪达唑仑 | 地西泮 | null | null | null | null | null | null | null | null | null | null |
8d12d7c2-228d-55b2-9010-23fd96675870 | 4 | B | 1 | What would be an appropirate Adult IV induction dose for midazolam? | 0.5 mg/kg | 0.1 mg/kg | 2-3 mg | 4 mg/kg | 咪达唑仑适合的成人静脉诱导剂量是多少？ | 0.5 mg/kg | 0.1 mg/kg | 2-3 mg | 4 mg/kg | null | null | null | null | null | null | null | null | null | null |
c585f8b9-5484-5762-a307-1f20f611ab8b | 4 | B | 1 | What is the elimination half time of Midazolam? | 21-37 hours | 1-4 hours | 10-20 hours | 5-10 hours | 咪达唑仑的消除半衰期是多少？ | 21-37 小时 | 1-4 小时 | 10-20 小时 | 5-10 小时 | null | null | null | null | null | null | null | null | null | null |
747468b2-6765-577d-be37-dc14ca79a624 | 4 | D | 1 | What is the elimination half time of Diazepam? | 5-10 hours | 1-4 hours | 10-20 hours | 21-37 hours | 地西泮的消除半衰期是多少？ | 5-10小时 | 1-4小时 | 10-20小时 | 21-37小时 | null | null | null | null | null | null | null | null | null | null |
76b8c0e9-d2e3-5a1d-b896-638d60ae3a56 | 4 | A | 1 | Describe the metabolism and excretion of the benzodiazepines? | Metabolized by liver and excreted in the urine | Metabolized in kidneys and excreted in feces | Metabolized by liver and excreted in feces | Metabolized in kidneys and excreted by urine | 描述苯二氮䓬类药物的代谢和排泄方式？ | 在肝脏代谢并通过尿液排泄 | 在肾脏代谢并通过粪便排泄 | 在肝脏代谢并通过粪便排泄 | 在肾脏代谢并通过尿液排泄 | null | null | null | null | null | null | null | null | null | null |
a8198545-da9e-51f8-a90e-429be2f0d846 | 4 | B | 1 | What effects do benzodiazepines exert upon the cardiovascular system? | No effect on cardiovascular system, even at high doses. | Decrease BP & PVR, especially in hypovolemic pt | Decrease ABP, CO & HR | Increase HR and decrease SV | 苯二氮䓬类药物对心血管系统有什么影响？ | 即使在高剂量下，对心血管系统无影响。 | 降低血压和外周血管阻力，尤其是在低血容量患者中。 | 降低动脉血压、心输出量和心率。 | 增加心率并降低每搏输出量。 | null | null | null | null | null | null | null | null | null | null |
d65ff90d-1ca6-5c2a-be33-f9c845008248 | 4 | D | 1 | Which of the following is not a cerebral effect of benzodiazepines? | Reduce CMRO2 & CBF | Increase the seizure threshold to prevent seizure | Anti-anxiety & sedative effects | Direct Analgesic Effects | 下列哪项不是苯二氮卓类药物的脑部效应？ | 降低CMRO2和CBF | 提高癫痫阈值以防止癫痫发作 | 抗焦虑和镇静作用 | 直接镇痛作用 | null | null | null | null | null | null | null | null | null | null |
25f2f4cf-b955-5b02-84e8-6e21554c9be3 | 3 | A | 1 | Where would you find benzodiazepine receptors? | Primarily on the postsynaptic nerve endings in the cerebral cortex | Pre-synaptic nerve endings in the brain stem and spinal cord. | Brain, spinal cord and peripheral tissue: pre-synaptic and post synaptic. | null | 苯二氮䓬受体主要存在于哪里？ | 主要在大脑皮层的突触后神经末梢 | 脑干和脊髓的突触前神经末梢。 | 大脑、脊髓和外周组织：突触前和突触后。 | null | null | null | null | null | null | null | null | null | null | null |
f64badad-21d4-5c13-8d5f-64485ab52f7c | 4 | B | 1 | What is a non-competitive antagonist? | A drug which alters the physiology of a cell by binding to plasma membrane or intracellular receptors | Binds to a site other than the agonist-binding domain | A drug which really hates playing sports, and instead takes a bunch of art classes. | A drug which inhibits a normal cellular function by competing with agonists for receptors | 什么是非竞争性拮抗剂？ | 通过与质膜或细胞内受体结合来改变细胞生理的药物 | 结合到激动剂结合域以外的位点 | 一个非常讨厌运动而选择上很多艺术课的药物。 | 通过与激动剂竞争受体来抑制正常细胞功能的药物 | null | null | null | null | null | null | null | null | null | null |
e8a0dd46-5175-5d80-8174-f3be61fc1512 | 4 | A | 1 | What drug would you choose to treat a pt with a benzodiazepine overdose? | Flumazenil, slow titration of 0.2 mg doses IV | Narcan, slow titration of 1-4mcg/kg | Flurazepam 15-30 mg | Just wait it out. | 你会选择哪种药物来治疗苯二氮卓类药物过量的患者？ | 氟马西尼，缓慢滴定0.2 mg剂量静脉注射 | 纳洛酮，缓慢滴定1-4 mcg/kg | 氟西泮 15-30 mg | 等待其自然消退。 | null | null | null | null | null | null | null | null | null | null |
0c01de2d-2e67-5485-9ebd-dca92118b4d9 | 4 | B | 1 | Which benzo would be used to treat panic attacks? | Lorazepam | Alprazolam | Flurazepam | Diazepam | 哪种苯二氮卓类药物用于治疗惊恐发作？ | 劳拉西泮 | 阿普唑仑 | 氟西泮 | 地西泮 | null | null | null | null | null | null | null | null | null | null |
9cf178f3-0b10-5f0b-a906-1885eb2a307c | 4 | C | 2 | How much oral midazolam would you give to a child weighing 40 kg? | 40 mg | 4 mg | 20 mg | 60 mg | 你会给一个体重40公斤的孩子服用多少口服咪达唑仑？ | 40毫克 | 4毫克 | 20毫克 | 60毫克 | null | null | null | null | null | null | null | null | null | null |
0e69aae9-08e5-5bf8-9c2a-ef8f34193ffe | 3 | A | 1 | You are holding a room temperature bottle of thiopental that was mixed 5 days ago. Can you still use it? | Yes, still good! | Nope, it is only stable for 2 days | If it had been refrigerated it would be good, but now it is not. Don't use. | null | 你手里拿着一瓶在室温下放置了5天的硫喷妥钠。你还能使用它吗？ | 是的，还可以用！ | 不行，它只能稳定2天 | 如果冷藏过就可以用，但现在不行。不要用。 | null | null | null | null | null | null | null | null | null | null | null |
d2ed33c8-8b86-5998-9fb3-fabbe409b76a | 4 | A | 1 | A Barbituate with a sulfur atom on the #2 carbon is called a... | Thiobarbituates | Oxybarbituates | Pentabarbituate | Sulbarbituates | 在第2号碳上有一个硫原子的巴比妥酸盐被称为... | 硫代巴比妥酸盐 | 氧代巴比妥酸盐 | 戊巴比妥酸盐 | 硫巴比妥酸盐 | null | null | null | null | null | null | null | null | null | null |
296a5893-d98e-58c3-83ed-bdca13329b49 | 3 | B | 1 | What is the MOA of barbituates? | Act at stereospecific receptors at presynaptic and postsynaptic sites in the central nervous system– brain(periaqueductal gray, amygdala, corpus striam, and hypothalmus) and spinal cord(substanstantia geltinosa) and in the peripheral tissues. | Depression of the reticulcar activating system, suppression of excitatory neurotranmitters and enhancement of inhibitory neurotransmitters. | Receptor binding enhances the inhibitory effects of various neurotransmitter by facilitating GABA receptor binding. This opens chloride gating channels, producing hyperpolarization of post synaptic cell membranes and rendering post synaptic neurons more resistant to excitation. | null | 巴比妥类药物的作用机制是什么？ | 在中枢神经系统（脑的导水管周围灰质、杏仁核、纹状体和下丘脑）和脊髓（胶状质）以及外周组织的突触前和突触后部位的立体特异性受体上起作用。 | 抑制网状激活系统，抑制兴奋性神经递质并增强抑制性神经递质。 | 受体结合通过促进GABA受体结合增强各种神经递质的抑制效应。这打开氯离子通道，使突触后细胞膜超极化，使突触后神经元更难被激发。 | null | null | null | null | null | null | null | null | null | null | null |
ef347e06-8405-5d91-86a6-d02a77c7c235 | 4 | D | 1 | Duration of action of highly lipid soluble barbituates is determined by... | Hepatic Oxidation | Lipid Solubility | Renal Excretion | Redistribution | 高脂溶性巴比妥类药物的作用持续时间取决于... | 肝脏氧化 | 脂溶性 | 肾脏排泄 | 重新分布 | null | null | null | null | null | null | null | null | null | null |
ff127121-6c5f-5f20-88cf-470aed6df2d0 | 2 | A | 1 | The elimination half time of Methohexital is ~4 hours. | True | False | null | null | Methohexital 的消除半衰期约为 4 小时。 | 正确 | 错误 | null | null | null | null | null | null | null | null | null | null | null | null |
55eaaf89-b6e2-53c4-a345-a270ebfa034d | 4 | C | 1 | What is responsible for the quick awakening associated with a single dose of thiopental? | Rapid hepatic oxidation | Rapid renal excretion | Redistribution | Patient respiratory rate | 是什么导致与单剂量硫喷妥钠相关的快速苏醒？ | 快速肝脏氧化 | 快速肾脏排泄 | 重新分布 | 患者呼吸频率 | null | null | null | null | null | null | null | null | null | null |
b4abb820-f0d8-597b-b326-750b651f8daf | 2 | B | 1 | Unlike the benzo's, Barbituates are known to increase CBF and ICP. | True | False | null | null | 与苯二氮卓类药物不同，巴比妥类药物已知会增加脑血流量（CBF）和颅内压（ICP）。 | 正确 | 错误 | null | null | null | null | null | null | null | null | null | null | null | null |
92280ffb-4481-5ee8-b9c3-f40075ae4ffa | 4 | D | 1 | How much methohexital should be given to a pt undergoing ECT? | 0.5 mg/kg IV | 20 mg/kg via rectal suppository | 5 mg/kg PO | > 1mg/kg IV | 接受电休克治疗的患者应给予多少甲己酯？ | 0.5 mg/kg 静脉注射 | 20 mg/kg 直肠栓剂 | 5 mg/kg 口服 | > 1mg/kg 静脉注射 | null | null | null | null | null | null | null | null | null | null |
3a5922c2-09c3-5e77-9979-1da83eb3d319 | 3 | A | 1 | What is the MOA of opioids? | Act at stereospecific receptors at presynaptic and postsynaptic sites in the central nervous system. mimic the endogenous endorphines to inhibit pain transmission. | Receptor binding enhances the inhibitory effects of various neurotransmitter by facilitating GABA receptor binding. | Depression of the reticulcar activating system, suppression of excitatory neurotranmitters and enhancement of inhibitory neurotransmitters. | null | 阿片类药物的作用机制是什么？ | 在中枢神经系统的突触前和突触后部位的立体特异性受体上起作用。模仿内源性内啡肽以抑制疼痛传递。 | 受体结合通过促进GABA受体结合来增强各种神经递质的抑制作用。 | 抑制网状激活系统，抑制兴奋性神经递质并增强抑制性神经递质。 | null | null | null | null | null | null | null | null | null | null | null |
ba4422c4-0ff2-5ea3-a1f6-15bbf8aa78b4 | 4 | D | 1 | Which of the following is NOT an endogenous peptide? | Endorphin | Ekephalin | Dynorphine | Epinorphin | 以下哪一项不是内源性肽？ | 内啡肽 | 脑啡肽 | 强啡肽 | 肾上腺啡肽 | null | null | null | null | null | null | null | null | null | null |
b91cb59b-88e0-5535-be68-de7648bd5688 | 4 | A | 1 | Which opioid receptor produces ONLY spinal analgesia. | Mu2 | Kappa | Mu1 | Delta | 哪种阿片受体仅产生脊髓镇痛。 | Mu2 | Kappa | Mu1 | Delta | null | null | null | null | null | null | null | null | null | null |
32c39b6d-3c89-5e96-a0bb-40918ad2950c | 4 | C | 1 | What are the metabolites of morphine? | Morphine 3-gluconiride which is active and induces analgesia and resp depression, & Mophine 6-gluconiride which is inactive | Morphine 3-gluconiride & Mophine 6-gluconiride both of which are inactive. | Morphine 3-gluconiride which is inactive, & Mophine 6-gluconiride which is active and induces analgesia and resp depression | Morphine 3-gluconiride & Mophine 6-gluconiride both of which are active and cause respiratory depression and analgesia | 吗啡的代谢产物是什么？ | 吗啡-3-葡萄糖苷酸是活性的，诱导镇痛和呼吸抑制，吗啡-6-葡萄糖苷酸是非活性的 | 吗啡-3-葡萄糖苷酸和吗啡-6-葡萄糖苷酸都是非活性的。 | 吗啡-3-葡萄糖苷酸是非活性的，吗啡-6-葡萄糖苷酸是活性的，诱导镇痛和呼吸抑制 | 吗啡-3-葡萄糖苷酸和吗啡-6-葡萄糖苷酸都是活性的，导致呼吸抑制和镇痛 | null | null | null | null | null | null | null | null | null | null |
a50c7caa-fbd5-5481-86df-0b215296523b | 4 | D | 1 | 30mg of Ketorolac would be equivalent to how much morphine? | 1 mg | 30 mg | 15 mg | 10 mg | 30毫克酮咯酸氨丁三醇相当于多少吗啡？ | 1 毫克 | 30 毫克 | 15 毫克 | 10 毫克 | null | null | null | null | null | null | null | null | null | null |
ba9d9317-179e-5beb-8395-c067ce4bad12 | 4 | D | 1 | Put these medications in order of shortest elimination half time to longest: Midazolam, Diazepam, Lorazepam | Midazolam < Diazepam < Lorazepam | Diazepam < Lorazepam < Midazolam | Lorazepam < Midazolam < Diazepam | Midazolam < Lorazepam < Diazepam | 将这些药物按消除半衰期从短到长的顺序排列：咪达唑仑，地西泮，劳拉西泮 | 咪达唑仑 < 地西泮 < 劳拉西泮 | 地西泮 < 劳拉西泮 < 咪达唑仑 | 劳拉西泮 < 咪达唑仑 < 地西泮 | 咪达唑仑 < 劳拉西泮 < 地西泮 | null | null | null | null | null | null | null | null | null | null |
eea2956f-9c9a-5188-8527-244527257dcb | 4 | B | 1 | Which opioid receptors are responsible for physical dependence? | Mu1 & Mu2 | Mu2 & Delta | Mu1 & Kappa | Kappa & Delta | 哪些阿片受体负责身体依赖？ | Mu1 和 Mu2 | Mu2 和 Delta | Mu1 和 Kappa | Kappa 和 Delta | null | null | null | null | null | null | null | null | null | null |
d942e7f5-2491-5395-ab9d-8cc420622540 | 4 | D | 1 | What is the respiratory pattern associated with barbituates upon awakening? | Decrease Tv and Increase RR | Increase Tv and RR | Increase Tv and decrease RR | Decrease Tv and RR | 巴比妥类药物苏醒时的呼吸模式是什么？ | 潮气量减少，呼吸频率增加 | 潮气量和呼吸频率增加 | 潮气量增加，呼吸频率减少 | 潮气量和呼吸频率减少 | null | null | null | null | null | null | null | null | null | null |
ab0b5120-5aa1-5c3e-9dd4-8718b2a4b255 | 3 | C | 2 | When doing a pre-op evaluation for a pt you notice the pt has low albumin levels. How would this effect the amount of Midazolam given to the pt for pre-medication? | You would need to increase the amount given in order to reach the desired effect | You would not change the dose at all. | You would decrease the amount of drug given since this pt may be at risk for overdose. | null | 在进行术前评估时，你注意到患者的白蛋白水平较低。这将如何影响给予患者咪达唑仑作为术前用药的剂量？ | 你需要增加给药量以达到预期效果。 | 你不会改变剂量。 | 你会减少给药量，因为该患者可能有过量的风险。 | null | null | null | null | null | null | null | null | null | null | null |
d312e61a-01ce-553b-aaaa-c52203bde507 | 4 | C | 1 | What is GABA? | The major excitatory neurotransmitter and is important in agonizing the effects of amino acid transmitter. | Proteins or glycoproteins that are present on the cell surface, on an organelle within the cell, or in the cytoplasm. | The major inhibitory neurotransmitter and is important in antagonizing the effects of amino acid transmitter. | Refers to the portion of the chemical structured composed of a benzene ring fused to a seven-membered diazepine ring | 什么是GABA？ | 主要的兴奋性神经递质，对氨基酸递质的作用有重要的激动作用。 | 存在于细胞表面、细胞内的细胞器或细胞质中的蛋白质或糖蛋白。 | 主要的抑制性神经递质，对氨基酸递质的作用有重要的拮抗作用。 | 指的是由苯环与七元二氮杂卓环融合而成的化学结构部分。 | null | null | null | null | null | null | null | null | null | null |
1946abb2-552f-584b-b6f7-f460cdbd2bf6 | 4 | D | 1 | How does Sufentanil compare to Morphine? | 1/10 as potent | 10 times as potent | 100 times as potent | 1,000 as potent | 舒芬太尼与吗啡相比如何？ | 效力为1/10 | 效力为10倍 | 效力为100倍 | 效力为1,000倍 | null | null | null | null | null | null | null | null | null | null |
6d75c970-2b1c-5c13-887b-46530dd4f375 | 4 | A | 1 | Which benzodiazepine is primarily used for induction of anesthesia? | Midazolam | Propofol | Thiopental | Etomidate | 哪种苯二氮䓬类药物主要用于麻醉诱导？ | 咪达唑仑 | 丙泊酚 | 硫喷妥钠 | 依托咪酯 | null | null | null | null | null | null | null | null | null | null |
1fd46658-3ada-5cae-b597-4c220ec5c08f | 4 | C | 1 | Which of the following is not an effect of opiods? | Chest wall rigidity | Fetal respiratory depression | Anterograde Amnesia | Constipation | 以下哪项不是阿片类药物的作用？ | 胸壁僵硬 | 胎儿呼吸抑制 | 顺行性遗忘 | 便秘 | null | null | null | null | null | null | null | null | null | null |
8bd9ba5c-b64e-55d3-a014-ee345c484534 | 5 | B | 1 | Which of the following is not a factor which increases risk of respiratory depression with opioids? | High opioid dose | High lipid solubility | Administration of other sedatives | Lack of tolerance | 以下哪项不是增加阿片类药物引起呼吸抑制风险的因素？ | 高剂量阿片类药物 | 高脂溶性 | 使用其他镇静剂 | 缺乏耐受性 | Advanced age | 高龄 | null | null | null | null | null | null | null | null |
dcc7cad1-cf8b-5461-878b-32965d9f73cc | 4 | C | 1 | How is remifentanil different than other opioids? | Shortest acting opioid | Stronger acting than Fentanyl | Structurally unique due to ester linkage | Few side effects | 瑞芬太尼与其他阿片类药物有何不同？ | 作用时间最短的阿片类药物 | 作用强于芬太尼 | 由于酯键而结构独特 | 副作用少 | null | null | null | null | null | null | null | null | null | null |
465938ed-19df-5bad-a437-ad3254c8dc05 | 4 | C | 1 | Substitutions on the carbon atoms of barbituates determine all of the following except: | Hypnotic potency | Anti-convulsant properties | Protein binding | Duration of action | 巴比妥类药物的碳原子上的取代基决定了以下所有特性，除了： | 催眠效力 | 抗惊厥特性 | 蛋白结合 | 作用持续时间 | null | null | null | null | null | null | null | null | null | null |
eaadfcb9-138d-5418-aa29-c43e98128240 | 4 | B | 1 | What would be an appropriate loading dose for remifentanil? | 5-20 microgram | 1 mcg/kg | 0.5 mg/kg | 5 mcg/kg | 瑞芬太尼的合适负荷剂量是多少？ | 5-20 微克 | 1 微克/公斤 | 0.5 毫克/公斤 | 5 微克/公斤 | null | null | null | null | null | null | null | null | null | null |
5f898723-e0de-5c56-bd73-a8861a97e113 | 4 | B | 1 | Is Thiopental safe to give during pregnancy? | No! | Up to 4mg/kg, yes | Yes, it does not cross the placental barrier and even a high dose will not effect the fetus | Only minimal dose of 0.5 mg/kg. | 硫喷妥钠在怀孕期间使用是否安全？ | 不安全！ | 是的，最多4mg/kg | 是的，它不会穿过胎盘屏障，即使是高剂量也不会影响胎儿 | 仅限于0.5 mg/kg的最小剂量。 | null | null | null | null | null | null | null | null | null | null |
ea601da0-3d77-5146-9a29-cb01ff06251a | 4 | D | 1 | A barbituate with an oxygen atom on the #2 carbon would be called a... | Thiobarbituates | Malobarbituates | Pentabarbituates | Oxybarbituate | 在第2号碳上有一个氧原子的巴比妥酸盐被称为... | 硫代巴比妥酸盐 | 麦洛巴比妥酸盐 | 戊巴比妥酸盐 | 氧巴比妥酸盐 | null | null | null | null | null | null | null | null | null | null |
19a320af-699f-5ca4-b2b8-40b04d8a732b | 4 | C | 1 | Sodium Thiopental is a contraindication in which patients? | History of neurologic distrubances | History of hemolytic amenia | Acute intermittent porphyria | Immunosuppression | 硫喷妥钠在哪些患者中是禁忌症？ | 有神经系统障碍病史 | 有溶血性贫血病史 | 急性间歇性卟啉症 | 免疫抑制 | null | null | null | null | null | null | null | null | null | null |
c79c49eb-7cab-5b5c-8e8f-dee1ce484a5a | 4 | D | 1 | Which opioid receptor causes depression of ventilation, physical dependence, minimal constipation & urinary retention? | Mu1 | Mu2 | Kappa | Delta | 哪种阿片受体会导致通气抑制、身体依赖、轻微便秘和尿潴留？ | Mu1 | Mu2 | Kappa | Delta | null | null | null | null | null | null | null | null | null | null |
e40d163a-bf9c-5137-beee-a73edcad95b1 | 4 | C | 1 | How is midazolam unique in comparison to other benzo's? | It is the only benzo safe to give to pregnant women. | Is known to cause pain upon injection, but has minimal respiratory depression | It is hydrophilic and becomes lipid soluble upon exposure to blood. | It is not highly protein bound like the other benzo's and thus more is available for use by the body. | 与其他苯二氮卓类药物相比，咪达唑仑有何独特之处？ | 它是唯一一种对孕妇安全的苯二氮卓类药物。 | 已知会引起注射时疼痛，但呼吸抑制最小。 | 它是亲水性的，暴露于血液后变为脂溶性。 | 它不像其他苯二氮卓类药物那样高度蛋白结合，因此更多可供身体使用。 | null | null | null | null | null | null | null | null | null | null |
8d5e280a-2e1f-57c5-80ef-debc16cabd47 | 2 | B | 1 | Benzodiazepines are preferred as a pre-medication for anesthesia because they do not cause any respiratory depression in patients. | True | False | null | null | 苯二氮䓬类药物作为麻醉前用药的首选是因为它们不会导致患者呼吸抑制。 | 正确 | 错误 | null | null | null | null | null | null | null | null | null | null | null | null |
3f3bde22-a38a-5cea-ae48-f44a7acc5e53 | 4 | A | 1 | How do midazolam and diazepam compare to one another? | Midazolam has 2 times the affinity for benzo receptors | Diazepam has 3 times the affinity for benzo receptors | Diazepam is hydrophilic | Midazolam has a much londer elimination half time | 咪达唑仑和地西泮如何相互比较？ | 咪达唑仑对苯二氮卓受体的亲和力是地西泮的2倍 | 地西泮对苯二氮卓受体的亲和力是咪达唑仑的3倍 | 地西泮是亲水性的 | 咪达唑仑的消除半衰期更长 | null | null | null | null | null | null | null | null | null | null |
dd9aadf8-d9ec-584b-913f-6a811d951de5 | 4 | D | 1 | What is the MOA of Benzo's? | Blockade of chloride channels leading to depolarization and inhibition of neurotransmitter | Inhibition of cyclooxygenase activity | Inhibition of GABA receptor binding which leads to degredation of GABA, preventing it from exerting it's effect. | Enhances the inhibitory effects of various neurotransmitter by facilitating GABA receptor binding. This opens chloride channels and causes hyperpolarization. | 苯二氮卓类药物的作用机制是什么？ | 阻断氯离子通道导致去极化和神经递质的抑制 | 抑制环氧合酶活性 | 抑制GABA受体结合，导致GABA降解，阻止其发挥作用。 | 通过促进GABA受体结合增强各种神经递质的抑制作用。这会打开氯离子通道并导致超极化。 | null | null | null | null | null | null | null | null | null | null |
2f825960-94d1-5973-ba51-5a64494402aa | 3 | A | 1 | Which of the Benzodiazepines reviewed has the slowest onset of action and why? | Lorazepam- due to lower lipid solubility | Midazolam- due to its water solubility | Diazepam- due to rapid redistribution | null | 在所审查的苯二氮䓬类药物中，哪一种的起效最慢，为什么？ | 劳拉西泮-由于较低的脂溶性 | 咪达唑仑-由于其水溶性 | 地西泮-由于快速再分布 | null | null | null | null | null | null | null | null | null | null | null |
bdf0f8f2-9787-57bc-9704-df783841293d | 4 | C | 1 | What is Substance P? | The major inhibitory neurotransmitter. | An active metabolite of opioid metabolism which relieves pain | An excitatory neurotransmitter presumed to be released by terminals of pain fibers | A rapper? | 什么是P物质？ | 主要的抑制性神经递质。 | 阿片类药物代谢的活性代谢产物，可缓解疼痛。 | 一种兴奋性神经递质，推测由疼痛纤维末端释放。 | 一个说唱歌手？ | null | null | null | null | null | null | null | null | null | null |
f2da649e-ae0c-5ac9-891f-bbc37e84fa4c | 2 | B | 1 | A Competitive antagonist binds to a site other than the agonist binding domain. | True | False | null | null | 竞争性拮抗剂结合在激动剂结合域以外的位点。 | 正确 | 错误 | null | null | null | null | null | null | null | null | null | null | null | null |
f817846f-6736-5d23-b43f-7dc734999f79 | 4 | A | 1 | How does meperidine compare to morphine? | 1/10 as potent | 10 times as potent | 100 time as potent | 1,000 times as potent | 哌替啶与吗啡相比如何？ | 效力为1/10 | 效力为10倍 | 效力为100倍 | 效力为1,000倍 | null | null | null | null | null | null | null | null | null | null |
4a0833f1-e61a-5d08-8a7f-f1601fc72a97 | 4 | A | 1 | Which of the following is true regarding benzodiazepines? | Amnesitic effects are greater than sedative effects | Produce sufficient skeletal muscle relaxation for surgery | Have a high tendency of tolerance compared to barbiturates | Longer duration of sedation than amnesia | 关于苯二氮䓬类药物，下列哪项是正确的？ | 遗忘效应大于镇静效应 | 产生足够的骨骼肌松弛以用于手术 | 与巴比妥类药物相比，耐受性倾向较高 | 镇静持续时间长于遗忘 | null | null | null | null | null | null | null | null | null | null |
6708492a-04e5-56e6-867a-b915c3f11dc1 | 4 | C | 1 | Which of the following is NOT a pharmacological effect of benzodiazepines? | Amnesia | Anxiolysis | Analgesia | Anticonvulsant | 下列哪一项不是苯二氮䓬类药物的药理作用？ | 遗忘 | 抗焦虑 | 镇痛 | 抗惊厥 | null | null | null | null | null | null | null | null | null | null |
3947f0e1-574f-5c9c-87ba-8658fe995031 | 4 | B | 1 | How is remifentanil metabolized? | 90% metabolized to normeperidine,1/2 as active as a analgesic | By nonspecific plasma esterase inactive metabolites | Metabolized via conjugation with glucuronic acid | Metabolized via hepatic oxidation | 瑞芬太尼是如何代谢的？ | 90%代谢为去甲哌替啶，作为镇痛剂活性为其一半 | 通过非特异性血浆酯酶代谢为无活性代谢物 | 通过与葡萄糖醛酸结合代谢 | 通过肝脏氧化代谢 | null | null | null | null | null | null | null | null | null | null |
8dfa4aa3-1282-55f9-b7ee-2c706bc0c71a | 3 | A | 1 | Endorphin stimulates which opioid receptor? | Mu | Kappa | Delta | null | 内啡肽刺激哪种阿片受体？ | μ受体 | κ受体 | δ受体 | null | null | null | null | null | null | null | null | null | null | null |
dba1b1f8-07d3-5050-a1fc-7a306e0580f1 | 4 | C | 1 | Distribution of barbituates depends on all of the following except... | Lipid Solubility | Protein binding | Hepatic oxidation | Degree of ionization | 巴比妥类药物的分布取决于以下所有因素，除了... | 脂溶性 | 蛋白结合 | 肝脏氧化 | 电离程度 | null | null | null | null | null | null | null | null | null | null |
bd4ecc93-bfa5-5650-ac00-702f9d4ed957 | 4 | A | 1 | Which benzodiazepine is primarily used to treat anxiety? | Lorazepam | Midazolam | Diazepam | Temazepam | 哪种苯二氮䓬类药物主要用于治疗焦虑？ | 劳拉西泮 | 咪达唑仑 | 地西泮 | 替马西泮 | null | null | null | null | null | null | null | null | null | null |
b868440d-d858-50e2-852c-a37217501a84 | 4 | C | 1 | How does fentanyl compare to morphine? | 1/10 as potent | 10 times as potent | 100 times as potent | 1000 times as potent | 芬太尼与吗啡相比如何？ | 效力为1/10 | 效力为10倍 | 效力为100倍 | 效力为1000倍 | null | null | null | null | null | null | null | null | null | null |
30e67074-ffaa-50df-8be7-1430dd919d76 | 4 | D | 2 | Why should you be cautious when giving both an opioid and a benzo together? | You increase risk for arrythmias | Patient may lose respiratory drive | You may increase ICP & SVR | You may severely reduce ABP | 为什么在同时给予阿片类药物和苯二氮卓类药物时要谨慎？ | 你增加了心律失常的风险 | 患者可能会失去呼吸驱动 | 你可能会增加颅内压和全身血管阻力 | 你可能会严重降低动脉血压 | null | null | null | null | null | null | null | null | null | null |
87788817-1cff-5141-b623-ae3ac003fea0 | 4 | B | 1 | Epidural or subarachnoid placement of opioids is based on activation of which receptors? | Kappa | Mu | Delta | All the above | 硬膜外或蛛网膜下腔放置阿片类药物是基于激活哪种受体？ | κ受体 | μ受体 | δ受体 | 以上所有 | null | null | null | null | null | null | null | null | null | null |
2bd18367-c09f-5f20-abd4-c462f65cef55 | 4 | A | 1 | What is the half life of Narcan? | 60-90 minutes | 30-45 minutes | 3 hours | 4-6 hours | Narcan 的半衰期是多少？ | 60-90 分钟 | 30-45 分钟 | 3 小时 | 4-6 小时 | null | null | null | null | null | null | null | null | null | null |
8ac20f59-b87d-554f-b095-60841da1b8b3 | 4 | C | 1 | Define Affinity: | Inhibit or block responses caused by an agonist | Drugs which alter the physiology of a cell by binding to plasma membrane or intracellular receptors | The strength of binding between drug and receptor | Binds to a site other than the agonist-binding domain | 定义亲和力： | 抑制或阻断由激动剂引起的反应 | 通过与质膜或细胞内受体结合来改变细胞生理的药物 | 药物与受体之间结合的强度 | 结合到激动剂结合域以外的位点 | null | null | null | null | null | null | null | null | null | null |
5c9903b3-c33e-5b71-ae59-4c3ed675566b | 4 | B | 1 | All benzo's share what similarities? | All are highly alkaline solutions | Composed of a benzene ring fused to a seven-membered diazepine ring | They are safe to be given during pregnancy | Composed of malonic acid and urea | 所有苯二氮卓类药物有什么相似之处？ | 都是高度碱性溶液 | 由一个苯环和一个七元二氮杂卓环融合而成 | 在怀孕期间使用是安全的 | 由丙二酸和尿素组成 | null | null | null | null | null | null | null | null | null | null |
16b6e98c-f287-5400-8015-c6f2daf42d50 | 5 | A | 1 | Which of the following is not one of the Top 4 side effects of neuraxial opioids? | Sedation | Pruritis | Nausea/Vomitting | Urinary retention | 以下哪一项不是神经轴麻醉阿片类药物的四大副作用之一？ | 镇静 | 瘙痒 | 恶心/呕吐 | 尿潴留 | Depressed ventilation | 呼吸抑制 | null | null | null | null | null | null | null | null |
9c517e99-9526-52fb-b1a9-96aab63571b1 | 3 | C | 2 | Which class of drug would to NOT give to a pt undergoing a cholangiogram? | Benzo's | Barbituates | Opioids | null | 在进行胆管造影的患者中，哪一类药物不应给予？ | 苯二氮卓类 | 巴比妥类 | 阿片类 | null | null | null | null | null | null | null | null | null | null | null |
a558ef56-6df9-50df-918d-84f9f448a782 | 4 | A | 1 | How are barbituate metabolized? | Hepatic Oxidation | Renal oxidation | Glomerular filtration | Broken down in small intestines and excreted in feces | 巴比妥类药物是如何代谢的？ | 肝脏氧化 | 肾脏氧化 | 肾小球过滤 | 在小肠中分解并通过粪便排出 | null | null | null | null | null | null | null | null | null | null |
a97f4627-8e2b-536c-9392-f44cc43f848d | 4 | A | 1 | What is an appropriate oral dose for pediatric pre-medication with midazolam? | 0.5 mg/kg | 1 mg/kg | 2-3 mg | 10 - 20 mcg/ kg | 咪达唑仑用于儿童术前镇静的合适口服剂量是多少？ | 0.5 mg/kg | 1 mg/kg | 2-3 mg | 10 - 20 mcg/ kg | null | null | null | null | null | null | null | null | null | null |
2e6c8076-6a98-51e7-8a25-4129103b483a | 4 | A | 2 | Which medication would you give to reverse post-op ventilatory depression of Fentanyl while maintaining analgesia? | Nalbuphine | Narcan, carefully titrated | Flumazenil | Switch to Meperidine | 在维持镇痛的同时，您会给予哪种药物来逆转芬太尼术后呼吸抑制？ | 纳布啡 | 小心滴定纳洛酮 | 氟马西尼 | 换用哌替啶 | null | null | null | null | null | null | null | null | null | null |
6b8566c0-6247-5622-ae82-197ff6b7d19e | 4 | C | 1 | The drug most commonly prescribed to treat opioid overdose is? | Flumazenil | Nalbuphine | Naloxone | Butorphanol | 最常用于治疗阿片类药物过量的药物是？ | 氟马西尼 | 纳布啡 | 纳洛酮 | 布托啡诺 | null | null | null | null | null | null | null | null | null | null |
e86542d1-271e-5edc-bd50-e6b2cd553370 | 4 | C | 1 | What is the elimination half time of Lorazepam? | 1-4 hours | 21-37 hours | 10-20 hours | 5-10 hours | 洛拉西泮的消除半衰期是多少？ | 1-4小时 | 21-37小时 | 10-20小时 | 5-10小时 | null | null | null | null | null | null | null | null | null | null |
ae835a26-8c13-5a5c-8565-9b0a5bcfe4a0 | 4 | C | 1 | You have just given you pt Midazolam, how long would you expect to wait to see onset of the drug? | 3-5 minutes | 20-25 minutes | 30-60 seconds | 2 minutes | 你刚给病人使用了咪达唑仑，你预计需要等待多长时间才能看到药物的起效？ | 3-5分钟 | 20-25分钟 | 30-60秒 | 2分钟 | null | null | null | null | null | null | null | null | null | null |
c260765d-afac-5fe0-ab7e-558118cdec9d | 4 | D | 1 | What medication would you give to treat an opioid overdose? | Flumazenil, slow titration of 0.2 mg doses | Nubain 10-20 mg | Lithium | Narcan 1-4 mcg/kg | 你会给什么药物来治疗阿片类药物过量？ | 氟马西尼，缓慢滴定0.2毫克剂量 | 纳布啡 10-20 毫克 | 锂 | 纳洛酮 1-4 微克/千克 | null | null | null | null | null | null | null | null | null | null |
17fff495-3956-5737-b7f4-e3d1421588d6 | 4 | D | 2 | You are the SRNA for Mr. Chaviano who is just our of surgery. He has a past medical histort of HTN, palpitations, schizophrenia, & GERD. He is shivering in the PACU and the nurse requests something to help. What do you do? | Give some Narcan to reverse your opioids. | Give Meperidine to treat the shivering | Give Fentanyl to treat shivering | Find some warm blankets and cover him up. | 您是刚刚做完手术的Chaviano先生的麻醉护士。他有高血压、心悸、精神分裂症和胃食管反流病的病史。他在术后恢复室发抖，护士请求一些帮助。您会怎么做？ | 给一些纳洛酮来逆转阿片类药物。 | 给哌替啶来治疗发抖。 | 给芬太尼来治疗发抖。 | 找一些温暖的毯子盖住他。 | null | null | null | null | null | null | null | null | null | null |
f6592ee6-7444-53f6-8f6f-350c7e96110c | 3 | C | 1 | Enkephalin is responsible for stimulating which opioid receptor? | Mu | Kappa | Delta | null | 脑啡肽负责刺激哪种阿片受体？ | Mu | Kappa | Delta | null | null | null | null | null | null | null | null | null | null | null |
175ce3b9-65dd-59f7-89e1-7c17f75cf94f | 4 | A | 1 | How much methohexital would you expect to find excreted unchanged in the urine? | < 1% | 1-3 % | 5-10 % | 95% | 你预计在尿液中排泄的未改变的甲己酯是多少？ | < 1% | 1-3 % | 5-10 % | 95% | null | null | null | null | null | null | null | null | null | null |
e412968a-1f1b-5f53-9ba8-0c440fc8ea8f | 4 | B | 1 | How long can Methohexital be refrigerated and stable for after mixing? | 2 weeks | 6 weeks | 6 days | 1 month | 混合后，甲己酯可以在冰箱中保存并保持稳定多长时间？ | 2周 | 6周 | 6天 | 1个月 | null | null | null | null | null | null | null | null | null | null |
76f82048-c36c-5828-b31a-e7c17928cf95 | 2 | B | 1 | The dose of Benzodiazepines required to reach a desired clinical endpoint is increased in the elderly compared to the younger patient. | True | False | null | null | 与年轻患者相比，老年患者达到预期临床终点所需的苯二氮卓类药物剂量增加。 | 正确 | 错误 | null | null | null | null | null | null | null | null | null | null | null | null |
27456300-2e8b-52a9-9e2c-4403da30af41 | 4 | C | 1 | What respiratory effects are associated with opioid? | Chest wall flaccidity | Increase RR with decrease Tv | Decrease RR and increase Tv | Increased response to CO2 | 阿片类药物与哪些呼吸效应相关？ | 胸壁松弛 | 呼吸频率增加，潮气量减少 | 呼吸频率减少，潮气量增加 | 对二氧化碳反应增强 | null | null | null | null | null | null | null | null | null | null |
2b3e7860-97f3-5a18-886d-a3fe6d8bc6fa | 4 | B | 1 | Which of the opioid receptors causes Euphoria, Miosis, Bradycardia, Urinary retention & Hypothermia? | Delta | Mu1 | Mu2 | Kappa | 哪种阿片受体会导致欣快感、瞳孔缩小、心动过缓、尿潴留和体温过低？ | Delta | Mu1 | Mu2 | Kappa | null | null | null | null | null | null | null | null | null | null |
9c0f3a8d-556c-5459-a3cf-8b9634a364a5 | 4 | D | 1 | Meperidine acts on which opioid receptors? | Mu & Delta | Only the Mu receptors | Delta & Kappa | Mu & Kappa | 哌替啶作用于哪些阿片受体？ | Mu 和 Delta | 仅 Mu 受体 | Delta 和 Kappa | Mu 和 Kappa | null | null | null | null | null | null | null | null | null | null |
60d1dc88-4f6b-5cac-9abe-f1f160612af5 | 4 | B | 1 | How much air space should there be in a CO2 absorber? | Equal to Tidal Volume | 2-3 times the Tidal Volume | 2 L/min | Minimal air space should be allowed. | CO2 吸收器中应有多少空气空间？ | 等于潮气量 | 潮气量的2-3倍 | 2 L/min | 应允许最小的空气空间。 | null | null | null | null | null | null | null | null | null | null |
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