nicolauduran45/horizon-intervention_areas-classifier
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Tariquidar inhibits P-glycoprotein drug efflux but activates ATPase activity by blocking transition to an open conformation
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P-glycoprotein (P-gp, ABCB1) is a drug pump that confers multidrug resistance. Inhibition of P-gp would improve chemotherapy. Tariquidar is a potent P-gp inhibitor but its mechanism is unknown. Here, we tested our prediction that tariquidar inhibits P-gp cycling between the open and closed states during the catalytic cycle. Transition of P-gp to an open state can be monitored in intact cells using reporter cysteines introduced into extracellular loops 1 (A80C) and 4 (R741C). Residues A80C/R741C come close enough (<7Å) to spontaneously cross-link in the open conformation (<7Å) but are widely separated (>30Å) in the closed conformation. Cross-linking of A80C/R741C can be readily detected because it causes the mutant protein to migrate slower on SDS-PAGE gels. We tested whether drug substrates or inhibitors could inhibit cross-linking of the mutant. It was found that only tariquidar blocked A80C/R741C cross-linking. Tariquidar was also a more potent pharmacological chaperone than other P-gp substrates/modulators such as cyclosporine A. Only tariquidar promoted maturation of misprocessed mutant F804D to yield mature P-gp. Tariquidar interacted with the transmembrane domains because it could rescue a misprocessed truncation mutant lacking the nucleotide-binding domains. These results show that tariquidar is a potent pharmacological chaperone and inhibits P-gp drug efflux by blocking transition to the open state during the catalytic cycle.
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publication
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[
[
"Health",
"Digital, Industry and Space"
]
] |
[
[
"Non-communicable and rare diseases",
"Tools, technologies and digital solutions for health and care, including personalised medicine"
]
] |
W2030885838
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OS DESAFIOS DO ENFERMEIRO EMERGENCISTA NA ASSISTÊNCIA PRESTADA AS MULHERES EM VIVÊNCIA DE VIOLÊNCIA DOMÉSTICA
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Introdução: No mundo inteiro a violência contra a mulher é entendida como um complicado obstáculo que ocasiona consequências que atingem toda a sociedade. Pela alta incidência desse tipo de violência, o setor saúde passou então a desempenhar um significativo papel no combate e identificação precoce desta que se tornou um grave problema de saúde pública. Objetivo: avaliação dos tantos desafios que os profissionais de enfermagem que exercem suas funções nos serviços de emergência enfrentam ao atender as mulheres que vivenciam no dia a dia a violência doméstica. Metodologia: Refere-se a uma revisão bibliográfica, produzido através da Biblioteca Virtual em Saúde (BVS), que utilizou como critérios de inclusão artigos publicados no período de 2010 a 2020, disponíveis na íntegra em português e inglês, originais e que abordasse a temática exposta, associados aos descritores. Resultado: Foram encontrados 16 artigos e após uma leitura detalhada dos materiais selecionados surgiram os seguintes subtópicos de análise: violência contra mulher: conceitos e tipo, evolução das medidas protetivas e das políticas públicas no combate a violência contra mulher, consequências vivencia de violência à saúde da mulher e a rede de atendimento e o enfermeiro emergencista como instrumento de combate à violência contra mulher. Considerações Finais: Constatou-se que o enfermeiro possui um significativo dever na luta contra a violência doméstica, entretanto para essa atuação ser efetiva é necessário que ele possua habilidades para conseguir acolher essas mulheres de maneira completa e mais humanizada possível.
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publication
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[
[
"Health",
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Health throughout the life course",
"Healthcare systems",
"Environmental and social health determinants"
]
] |
W4281868678
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Enertechnos capacitive transfer system for efficient electricity transmission and distribution.
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Our Capacitive Transfer System (CTS) is a new cable/line geometry that is inherently more efficient than conventional cable design. Instead of a solid ohmic conductor, the cable core is composed of coupled capacitors that transfer energy from the source to the load. Despite this, its other critical dimensions are identical to conventional lines and can be manufactured on conventional machinery with minimal adaptation. The ability of CTS to transfer power is based on its capacitance, which increases with the length of the cable, meaning longer sections of cable can transfer more power, without voltage drop, in direct contrast to conventional cables. Delivering up to 40% more active power and with voltage losses of only 2.57% (6x better than conventional cable). Voltage drop decreases with increased cable length and delivered power increases, these are both in direct contrast to conventional cables. CTS will allow significant capex and operational savings to the owners/operators of electrical grids. The main customers of Enertechnos will be the manufacturers of standard Transmission and Distribution (T&D) cables and lines. The users will be Transmission and Distribution Network Operators.
CTS delivers more, and better quality power which will have a long-term ongoing beneficial impact on system losses. We will sell licences to the manufacturers of T&D cables and charge 5% royalty on each km of cable they sell. Go-to-market segment will be the Distribution Network Operators. The global T&D infrastructure market was estimated to be ~$282 billion in 2016. The cable and line portion of this market was estimated to be worth $63 billion in 2017 rising to $90 billion in 2020. The senior management has over 100 years’ experience in starting, growing and managing businesses, holding senior executive and consultancy positions in the energy, IT and hi-tech industries. SME Instrument funding will provide crucial non-diluting funding to help us hold our first in-field pilot trial
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project/european
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[
[
"Climate, Energy and Mobility",
"Digital, Industry and Space"
]
] |
[
[
"Energy storage",
"Energy supply",
"Energy systems and grids"
]
] |
895632
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Cohesive bandages based on natural fibres, with antimicrobial and hydrophobic properties by mlse technology
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Cohesive support bandages are a kind of bandages that are used by professionals of the health sector, for fixing dressings and immobilization splints.
Carrying bandages for a long period can cause several inconveniences in patients. Thus, the possibility of conferring them with antimicrobial and hydrophobic properties, without loosing breathability, has become of great interest for the company Calvo Izquierdo S.L., a family-owned company that has positioned at the Spanish market for the development and production of this range of products.
However, currently bandages with the said properties can only be produced by using synthetic fibres, which results in a different feel to touch, reducing patient/user comfort and welfare.
The Multiple Laser Surface Enhancement technology (MLSE), originally developed for the metallurgic and electronic sectors, has proved to produce surface modifications, at nanoscale, of natural fibres such as wool, conferring them hydrophilic/hydrophobic properties.
In VENDA NATU-haft project, Calvo Izquierdo aims at implementing the MLSE technology in their manufacturing system to produce antimicrobial and hydrophobic bandages for sanitary use, based on natural fibres. The use of this technology for the deposition of the cohesive/adhesive coating is also considered. This implementation will allow the company to widen their product portfolio, being able to provide their customers with a new grade of cohesive bandages, based in natural fibres, with enhanced properties.
To get this objective, some adaptation of the current MLSE system will be required during VENDA NATU-haft project development. Some modifications in Calvo Izquierdo current production line may also be necessary to incorporate this technology.
Phase 1 of VENDA NATU-haft aims to ensure the viability of the project. A technical analysis on the viability of producing natural fibre-based, functional cohesive bandages by MLSE technology will be made and a business plan will be developed.
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project/european
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[
[
"Health",
"Digital, Industry and Space"
]
] |
[
[
"Health throughout the life course",
"Tools, technologies and digital solutions for health and care, including personalised medicine"
]
] |
174120
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Measure 3.4 POIR and 1.5 POPW Subsidies for working capital of Tajska Sp. z o.o.
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The project concerns support to the entrepreneur in providing liquidity and support to day-to-day activities due to the financial difficulties that have occurred to the entrepreneur as a result of the COVID-19 outbreak. Financial assistance under scheme SA.57015 (2020/N)
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project/regional
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[
[]
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[
[]
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Q2689869
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Motor cycle touring in New Zealand before 1915
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This article attempts to explain why the riders of motor-assisted bicycles before 1915 only wrote the briefest details of their long-distance journeys around New Zealand. Road, rail and telegraph infrastructure only started in New Zealand after 1870. This was 30 years after the first formal colonial settlements. The first motor vehicles imported into New Zealand were using these roads by 1897. The major problem of using personal transport was that of using primitive engined vehicles on crude and poorly made road surfaces. Motor cars could only be used on the streets of the main settlements whereas the bicycle could be used for out of town rides providing the cyclist had the physical strength to overcome the many obstacles. The motor attachment to a bicycle allowed riders to travel further while still using the riding techniques developed for cycling. The constant soaking of riders from rain and raging river crossings made the taking of writing materials difficult.
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publication
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[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations",
"Culture, cultural heritage and creativity"
]
] |
W1964825211
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Alpen Corridor South
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Paneuropean corridors are a new definition introduced by E.U. to support both internal market development and new E-W links between E.U. countries and accession countries.
Transport and accessibility represent strategic and long term policies for social and economic cohesion of the continent.
What is a corridor and how to realize it it’s still an open question, since european space has relevant differences according to geography, regional economies, local societies, and infrastructures existing stock.
We need to go deeper through the significance of the term Corridor, which means experiencing different spatial approaches to the complexity of this assumption and to clarify the role of actors and the nature of actions involved in implementation.
Transport is a relevant part of a corridor, but it means a set of different actions involving infrastructures, vehicles, technology, communication, organization, pricing policy, spatial impacts, etc.
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project/regional
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[
[
"Climate, Energy and Mobility",
"Digital, Industry and Space"
]
] |
[
[
"Clean, safe and accessible transport and mobility",
"Communities and cities",
"Smart mobility"
]
] |
interreg_353
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advanCing youth and women sociaL inclUSion in The mEditerRanean
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The potential of CLUSTER project relies on, first, the partnership made of entities who have previously run projects dealing with youth and women unemployment in the Mediterranean region. Second, it introduces the social economy as a key player in improving employment policies together with Technical and Vocational Education and Training (TVET) institutions and the private sector. Based on previous results and adapting to the new post-pandemic era which affected mostly youth and women, CLUSTER will build its strategy in three steps. First, it will refine the catalogues of skills needs in four sectors: blue, green, circular economy and sustainable agriculture. It will also identify the successful experiences and efficient practices. Second, it will train NEETs on-site and on-line together with traineeship scheme, coaching and tutoring to acquire skills and work experiences needed to enter the labour market. Finally, it will mainstream successful practices and methods to public authorities and policy makers. The ultimate aim is to create a supportive environment for the implementation of youth/women employment schemes.
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project/regional
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[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations"
]
] |
interreg_695
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Deconstruction as critical method in political theory
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Deconstruction as Critical Method in Political Theory
‘Deconstruction as Critical Method in Political Theory’ (DECON) explores the critical potential of deconstruction for three important - but contested - concepts in political theory: democracy, sovereignty and universality, and systematises deconstruction as a methodological and theoretical framework for political theory. This is done through methodological and conceptual development within deconstruction and through critical conversation with other approaches in political theory. The overall objective of DECON is to develop deconstruction as a systematic approach within political theory. The proposed research is highly relevant for current academic and political debates about the challenges to liberal democracy from populism, the representative character of contemporary democratic institutions, and the possibility for social critique in the face of post-truth politics. My wager is that deconstruction can provide a novel and productive perspective on these debates – but, in order to do so, it is necessary to develop deconstruction in a more systematic fashion so that it can enter into critical conversation with other, more mainstream approaches in political theory.
I pursue this project in the political theory research group in the Department of Political Science and in the Centre for Anthropological, Political and Social Theory (CAPS) at the University of Copenhagen (UCPH), where I will be part of an international research environment focusing on critique and critical theory in the social sciences. The expected impact of the Marie Skłodowska-Curie Action consists of two journal articles and a book manuscript as well as organisation of workshops and a reading group, seminar and conference presentations, and public dissemination activities. This is in addition to essential training n dissemination for non-academic audiences and in research and administrative leadership.
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project/european
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[
[]
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[
[]
] |
223821
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Launching the first non-invasive brain-monitoring system for the early detection and management of encephalopathy in preterm babies
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Over the last two decades preterm babies (neonates with less than 37 weeks of gestational period) have rise tremendously reaching 15 million births worldwide in 2014, and the figures are growing. Anyhow, despite we have been successful at maintaining alive premature babies until their live it’s not at risk, we are failing at solving important side-problems. Preterm babies are at high risk of suffering encephalopathies (brain damage) during the artificial gestational stage on the neonatal intensive-care units (NICUs). In fact, about 20% of babies born before 6.5 months gestation experience lasting brain damage. This leads to lifelong disorders such as attention deficit, autism, cerebral paralysis, and hearing or visual impairments.
To early detect cerebral damage in a precise manner it’s necessary to provide real time and accurate measures of cerebral oxygen metabolism and blood flow in the brain. This problem remains unsolved since current commercial solutions provide partial measurements or are extremely invasive. BabyLux will be the first device allowing early detect and manage encephalopathies in preterm-babies in a non-invasive and affordable manner by combining two leading photonic techniques.
Our product fall within the sub-segment of “monitoring equipment” for NICUs, which is a € 1.200M market growing at a CARG of 6.5%.BabyLux will be sold at a first commercialization stage to pre-clinical markets (research institutions studying brain damage in neonates). We will proceed in such way since to gain credibility among scientific community, easing the entrance to clinical segments. At a second commercialization stage we will approach clinical segments, in particular hospitals with NICUs. This mixed business model will allow HemoPhotonics to achieve a turnover of € 13 M at 5 years after the project compilation. We are requesting a SMEI Phase 1 to further define and corroborate our business assumptions.
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project/european
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[
[
"Health"
]
] |
[
[
"Health throughout the life course",
"Tools, technologies and digital solutions for health and care, including personalised medicine"
]
] |
218392
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Mucobiome-Mediated immune pathways in inflammatory bowel diseases
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Inflammatory Bowel Diseases (IBD) are chronic disorders characterized by persistent ulcerations in the gastrointestinal tract, drastically affecting the patient’s quality of life. Initially regarded as “Western diseases”, they have now become a global problem. Despite IBD being a set of inflammatory diseases, the underlying host immune pathways remain unclear, making it difficult to reliably treat and cure patients. The low-fiber Western diet, and the microbial communities that live in our intestines (the gut “microbiome”), have been proposed as major environmental contributors of the disease - but the mechanisms of their contribution are poorly understood.
Among the gut microbiome, the mucobiomes are defined as the microbial communities enzymatically geared to digest the host intestinal mucus layer – our first line of defense against invading pathogens. Their mucolytic activities are regulated by dietary fibers. Thus, we hypothesize that, under a low-fiber diet, the mucobiomes catalyze important disease-promoting immune pathways of IBD. Using an original animal model combining genetic susceptibility, dietary fiber deficiency and different microbiota compositions, we aim at highlighting (1) the role of the mucobiome in IBD pathogenesis, and (2) key immune-pathways regulated by the mucobiome. These objectives are ambitious, yet highly feasible given the expertise of the actors. The proposed work provides a unique dimension to understand the underlying pathogenic mechanisms of a key physiological trait of gut bacteria: host-secreted mucus degradation. The success of this project relies on a close interdisciplinary collaboration that will benefit to develop the researcher's career, the hosting group’s projects, the hosting institute's visibility, and establish innovative diet-based therapies for IBD patients.
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project/european
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[
[
"Health"
]
] |
[
[
"Non-communicable and rare diseases",
"Environmental and social health determinants"
]
] |
3741186
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The structure of the Myo4p globular tail and its function in ASH1 mRNA localization
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Type V myosin (MyoV)–dependent transport of cargo is an essential process in eukaryotes. Studies on yeast and vertebrate MyoV showed that their globular tails mediate binding to the cargo complexes. In Saccharomyces cerevisiae, the MyoV motor Myo4p interacts with She3p to localize asymmetric synthesis of HO 1 (ASH1) mRNA into the bud of dividing cells. A recent study showed that localization of GFP-MS2–tethered ASH1 particles does not require the Myo4p globular tail, challenging the supposed role of this domain. We assessed ASH1 mRNA and Myo4p distribution more directly and found that their localization is impaired in cells expressing globular tail–lacking Myo4p. In vitro studies further show that the globular tail together with a more N-terminal linker region is required for efficient She3p binding. We also determined the x-ray structure of the Myo4p globular tail and identify a conserved surface patch important for She3p binding. The structure shows pronounced similarities to membrane-tethering complexes and indicates that Myo4p may not undergo auto-inhibition of its motor domain.
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publication
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[
[
"Digital, Industry and Space"
]
] |
[
[
"Advanced Materials"
]
] |
W2156055657
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Verfahren zur Bewertung möglicher Trajektorien
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Es wird ein Verfahren zur Bewertung möglicher Trajektorien von Verkehrsteilnehmern einer Verkehrsumgebung beschrieben, mit den Schritten:Erfassen der Verkehrsumgebung mit statischen und dynamischen Merkmalen;Identifizieren mindestens eines Verkehrsteilnehmers;Ermitteln mindestens einer möglichen Trajektorie für den mindestens einen Verkehrsteilnehmer der Verkehrsumgebung;Bewerten der ermittelten, mindestens einen möglichen Trajektorie für den mindestens einen Verkehrsteilnehmer mittels eines adaptierten/trainierten Empfehlungsdienstes und der erfassten Verkehrsumgebung.
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patent
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[
[
"Digital, Industry and Space",
"Civil Security for Society"
]
] |
[
[
"Key digital technologies",
"Artificial intelligence and robotics",
"Advanced computing and big data"
]
] |
DE 102019209736 A
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MONITORING SYSTEM FOR RAILWAY TRACK LAYING AND MAINTENANCE
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1306506 Track positioning F PLASSER 22 Jan 1970 [22 Jan 1969] 3216/70 Heading B7N [Also in Division E1] In a railway track processing system in which, e.g. an old track is replaced or the ballast of a track is lifted and cleaned, the position of the new or processed track is determined by reference to a datum line or plane defined by the position of the old or unprocessed track. In the track replacing arrangement shown, in which a leading train loads the old track sleepers and supplies new rail 2 and a second train picks up the old rails, the last vehicle of the leading train carries a transmitter 7 directing a laser beam to the first vehicle 13 of the second train which carries track aligning tools 11 controlled by the beam signal picked up by receiver 10. The beam direction is determined by wheels 4, 5 of the vehicle 1 which are forced into engagement, by, e.g., an hydraulic ram 9, with a rail of the old track.
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patent
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[
[
"Digital, Industry and Space"
]
] |
[
[
"Manufacturing technologies"
]
] |
GB 321670 A
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Pilot eye gaze and gesture tracking for avionics systems using unobtrusive solutions
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As the capabilities of cockpit systems increase, the way in which the pilots interact with them evolves. At the same time, flight management concepts and tools continue to increase in complexity, as well as flight and non-flight data streams, which consequently challenges the pilots’ abilities to cope with the information they need to be aware of, and exerts pressure on their cognitive states.
In in framework of the development of new Human System Interfaces carried out in WP1.2.4 the Clean Sky 2 SYSTEMS ITD, the PEGGASUS project proposes an approach to bring innovative smart vision systems to cockpits. The system we propose to develop is a crew interface and monitoring system implementing eye gaze, face, and gesture tracking technologies to bring new functionalities to Human-Machine Interfaces in the cockpit. It consists in a set of NIR-sensitive cameras powered by Computer Vision and Machine Learning algorithms running on a central processing unit. Three prototypes will be developed from a standalone lab prototype, to a TRL5 model integrated in the topic leader’s “cockpit demonstrator”. The system design shall be compliant with aircraft cockpit installation, the operational environment and pre-certification requirements. The requirements defined at the beginning of the project with the topic leader’s inputs, will be verified after its successful integration into the “cockpit demonstrator” avionics.
PEGGASUS brings together partners able to cover the complete value chain of innovative product development: SERMA Engineering (FR), an OEM for aeronautical equipment, CSEM (CH) an RTD with proven experience in innovative technologies for aeronautics, ETHZ (CH) represented by the Geogaze lab that conducts cutting edge research with eye tracking technology, particularly for the use in aviation training, and Swiss (CH), an airline and potential end user who will provide expertise in crew interfaces and monitoring.
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project/european
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[
[
"Digital, Industry and Space",
"Civil Security for Society"
]
] |
[
[
"Key digital technologies",
"Artificial intelligence and robotics",
"Emerging enabling technologies",
"Advanced computing and big data"
]
] |
892485
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CAROTENOID BIOSYNTHESIS ENZYMES
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This invention relates to an isolated nucleic acid fragment encoding a carotenoid biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the carotenoid biosynthetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the carotenoid biosynthetic enzyme in a transformed host cell.
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patent
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[
[
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Bio-based innovation systems in the bioeconomy"
]
] |
US US9908789
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Type material designation and species description; addendum to “Distinctive Collembola Communities in the Mesovoid Shallow Substratum: Entomobryomorpha of the Sierra de Guadarrama National Park (Central Spain)”
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Désignation du matériel type et description d'espèce; addendum à « Communautés distinctes de collemboles dans le milieu souterrain superficiel: Entomobryomorpha du parc national de la Sierra de Guadarrama (centre de l'Espagne)». Les spécimens identifiés comme Entomobrya intermedia Brook, 1883 par Katz et al. (2015) ont été proposés comme une nouvelle espèce des États-Unis, Entomobrya katzi Jordana & Baquero n. sp. (Baquero et al. 2021). Cependant, le matériel type n'avait pas été désigné. Ici, nous fournissons une diagnose et désignons le matériel type pour Entomobrya katzi Jordana & Baquero n. sp.
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publication
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[
[
"Culture, Creativity and Inclusive Society",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Culture, cultural heritage and creativity"
]
] |
W4296576861
|
A sound fundament for our future buildings
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To ensure a healthy environment for people living and working in buildings, research and engineering in the area of building acoustics is essential. Developments in modern building concepts, such as sustainable low-energy consuming buildings, buildings with lightweight materials and open plan working environments, as well as the need to build in extremely noisy areas, require involvement of acoustic experts in order to successfully (re)design buildings without negatively impacting upon people’s health and well-being. Taking up current and future acoustic challenges requires innovative solutions based on a thorough understanding and mastering of modern methods and tools, as well as a holistic acoustic approach involving acoustic design, products and subjective evaluation. However, in the complex field of building acoustics, research activities typically are not holistic and have become slightly marginalised. As a consequence, there is a lack of building acoustics experts.
To meet the future acoustic needs of the built environment, Acoutect is constructed around two objectives: 1) Establish a long-lasting European-wide training programme on building acoustics, 2) Launch an innovative research programme. With these objectives, Acoutect will equip ESRs with skills to ensure acoustic quality of modern and future building concepts, and with excellent perspectives for a career in industry or academia within the area of building acoustics. The training and supervision to reach these objectives is offered by the Acoutect consortium composed of 5 academic and 7 non-academic participants. This consortium comprises various disciplines and sectors within building acoustics and beyond, promoting intersectoral, interdisciplinary and innovative training and mobility of the researchers within the project.
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project/european
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[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations",
"Culture, cultural heritage and creativity"
]
] |
217575
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(5158.03042018.125000125) WOODTECH 2018
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LE PROJET WOODTECH VOIT LA COLLABORATION DE 3 ENTREPRISES TOSCANES DANS LE SECTEUR DES MACHINES À BOIS QUI, À PARTIR DE L’ÉVÉNEMENT CLÉ, XYLEXPO 2018, LE PLUS GRAND SALON DU SECTEUR AU MONDE, AINSI QUE LA COMMUNICATION, LE MARKETING WEB, LES ACTIONS DE RECHERCHE ENTRANTES ET OPÉRATEURS, STRUCTURENT UN PROGRAMME D’INVESTISSEMENT POUR LES 8 MOIS D’UN PROJET TRÈS DIVERSIFIÉ ET CONCENTRÉ, VISANT À ATTAQUER LES NOMBREUX MARCHÉS INTERNATIONAUX QUE CE TYPE D’ENTREPRISES, PAR NATURE DU SECTEUR, CIBLE. LE PROJET COMPREND DONC LE POSTE DE DÉPENSES C1 POUR LE SALON XYLEXPO, LE POSTE C3 AVEC ACTIONS DE COMMUNICATION ET DE RÉALISATION D’ÉVÉNEMENTS, LA RUBRIQUE C4 POUR LA COORDINATION PAR CSM, UNE STRUCTURE OPÉRANT DANS LE SECTEUR DEPUIS LES ANNÉES 1990S ET LA RUBRIQUE C5 AU PROFIT DE L’UNE DES 3 SOCIÉTÉS DE RECHERCHE DES OPÉRATEURS SUR LES MARCHÉS DE RÉFÉRENCE DU PROGRAMME D’INVESTISSEMENT PROJECT.THE DÉTERMINE? POUR LES 3 SOCIÉTÉS PARTICIPANTES, UNE AUGMENTATION ESTIMÉE DE 3 À 5 % DU CHIFFRE D’AFFAIRES DE RISCO
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project/regional
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[
[
"Digital, Industry and Space"
]
] |
[
[
"Circular systems",
"Manufacturing technologies"
]
] |
Q4939529
|
Creative Campus 2020 — development project
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The CreativeKampus development package will be implemented as two separate projects: Creative Kampus 2020 development project and CreativeKampus 2020 investment project. The aim of the projects is to strengthen the conditions for education, entrepreneurship and research and development in the natural resources sector in the region by developing learning environments and promoting the use of new technologies. Primary production industries, in particular milk production, play an important role in the regional economy of Central Ostrobothnia, and education and training must meet the skills needs of working life. The aim is that the learning environment in livestock production in Kanus serves as a model for sustainable practices in areas such as animal welfare, feed production, the circular economy, biosafety and carbon-neutral operating models, and thereby promote the competitiveness of livestock farms in the region. The Creative Kampus 2020 development project explores the future dairy farm from the perspectives of well-being, functionality, automation, circular economy, biosafety and the latest technologies. The project designs a learning environment for livestock production that takes into account the needs of teaching and R & D activities, and the learning environment is designed to be pedagogically functional. The project will competitiveise the planning, construction and equipment procurement of the learning environment for livestock production, as well as equipment for simulation and animal care learning environments. During the project, information, models and experiences on planned and implemented solutions will be disseminated. The learning environments and the new equipment base will be closely integrated into teaching and R & D activities. The projects will result in two new innovation platforms in Central Ostrobothnia. Kpedun Kannu will have a modern learning environment in animal husbandry that serves education and R & D activities. Within the learning environment, there is another innovation platform, a digital bridge, which enables data to be transmitted between the learning environment and the collaborative network. The result is also a RDI platform service developed on innovation platforms and a digital service for educational purposes. Cooperation with universities, research institutes and businesses is increasing and deepening. The procurement of simulators and equipment diversifys the offer of training, creates new training services and promotes learning. The projects support environmental sustainability and promote equality. The use of simulators reduces the use of non-renewable resources and environmental risks. In the learning environment of livestock production, renewable energy solutions and the effects of operations on the environment are taken into account. New solutions to lighten technological work will promote equality and equality by changing the working image of physical work towards monitoring and monitoring. In an up-to-date learning environment, it is possible to acquire skills guided by gender and resources. The management of modern technologies equals the employment of different genders.
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project/regional
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[
[
"Culture, Creativity and Inclusive Society",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Social and economic transformations",
"Culture, cultural heritage and creativity"
]
] |
Q3753738
|
Energy efficiency in the transport sector in the EU-27: A dynamic dematerialization analysis
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Abstract Energy use in the European Union's (EU) transport sector amounted to 340 Mtoe 1 in 1999 with the following increasing trend up to 379 Mtoe in 2007 and a decrease from 2008 on, down to 365 Mtoe in 2010. This changing pattern posed several fundamental questions and uncertainties regarding the broader picture of energy efficiency and environmental protection. One of them refers to absolute changes in energy use efficiency in the transport sector over time and the ways of measuring efficiency. Traditional scientific approaches conceptualized to measure efficiency of energy use do not address annual dynamics of changes in the energy use in a given sector per capita. Thus, they are not precise enough for political and methodological purposes as they do not reflect the exact amount of energy consumed in the respective countries and societies. This paper shows a possible solution to this problem and a new perspective on measuring energy efficiency by using the product generational dematerialization (PGD) indicator. The PGD indicator allows for measuring energy efficiency as a dynamic change of consumption and population occurring simultaneously. Thus, it provides an extension to the traditional methodology commonly used for measuring efficiency. To visualize a practical application of this approach, the paper provides an example of evaluating energy efficiency in the transport sector in the EU-27 in 2000–2010. The results of the analysis show a clear materialization tendency in the transport sector (the energy consumption change exceeded the population growth) until 2007 and a reverse tendency (dematerialization) between 2008 and 2010. As energy consumption has a direct impact on environmental quality and exhaustion of natural resources, the paper points out the necessity of extending sustainable resource management policies by new methodologies and providing more efficient solutions for energy consumption in the transport sector.
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publication
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[
[
"Climate, Energy and Mobility"
]
] |
[
[
"Clean, safe and accessible transport and mobility",
"Energy systems and grids"
]
] |
W2111744511
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TRANSPORT SYSTEM
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A device for transporting passengers and goods has at least one stationary magnetic track (2) for carrying a vehicle (1) provided with a magnetic levitation device. The vehicle (1) can also be provided with a driving mechanism for street traffic. The vehicle (1) is designed as an individual vehicle with an interchangeable energy supply block (13) for street traffic. The energy supply block (13) may be removed in the area of coupling points of the magnetic track (2) and loaded in the area of uncoupling points of the magnetic track (2). After passing the coupling points and joining the magnetic track (2), the vehicle can be accelerated by magnetic fields acting along the magnetic track (2) in high speed areas. After leaving the magnetic track (2), the vehicle (1) may be driven by another driving system.
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patent
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[
[
"Climate, Energy and Mobility",
"Digital, Industry and Space"
]
] |
[
[
"Clean, safe and accessible transport and mobility",
"Smart mobility"
]
] |
DE 9200970 W
|
Transient small‐scale structure in the main auroral emission at Jupiter
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The main auroral emission at Jupiter results from the ionosphere-magnetosphere coupling current system associated with the corotation breakdown of iogenic plasma in the current sheet. The morphology and brightness of the main auroral emission are generally suggested to be stable during time intervals of the order of an hour. Here we reveal a transient small-scale structure in the main emission that is characterized by a localized brightness enhancement close to noon local time. The evolution of this small-scale structure is investigated in both hemispheres on the basis of far UV images obtained with the Hubble Space Telescope between 1997 and 2007. Our observations indicate that the transient feature vary within a few tens of minutes. As one plausible explanation based on Galileo observations, we suggest that the localized enhancement of the field-aligned currents associated with the transient structure is due to the shear induced by intermittent inward plasma flow near noon in the equatorial plane.
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publication
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[
[
"Digital, Industry and Space"
]
] |
[
[
"Space, including Earth observation"
]
] |
W2135649117
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Biomarkers of susceptibility: State of the art and implications for occupational exposure to engineered nanomaterials
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Rapid advances and applications in nanotechnology are expected to result in increasing occupational exposure to nano-sized materials whose health impacts are still not completely understood. Scientific efforts are required to identify hazards from nanomaterials and define risks and precautionary management strategies for exposed workers. In this scenario, the definition of susceptible populations, which may be at increased risk of adverse effects may be important for risk assessment and management. The aim of this review is to critically examine available literature to provide a comprehensive overview on susceptibility aspects potentially affecting heterogeneous responses to nanomaterials workplace exposure. Genetic, genotoxic and epigenetic alterations induced by nanomaterials in experimental studies were assessed with respect to their possible function as determinants of susceptibility. Additionally, the role of host factors, i.e. age, gender, and pathological conditions, potentially affecting nanomaterial toxicokinetic and health impacts, were also analysed. Overall, this review provides useful information to obtain insights into the nanomaterial mode of action in order to identify potentially sensitive, specific susceptibility biomarkers to be validated in occupational settings and addressed in risk assessment processes. The findings of this review are also important to guide future research into a deeper characterization of nanomaterial susceptibility in order to define adequate risk communication strategies. Ultimately, identification and use of susceptibility factors in workplace settings has both scientific and ethical issues that need addressing.
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publication
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[
[
"Health",
"Civil Security for Society"
]
] |
[
[
"Environmental and social health determinants"
]
] |
W2216522720
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Ancient projectile weapons from ice patches in northwestern Canada: identification of resin and compound resin-ochre hafting adhesives
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Abstract This article describes a study of adhesive residues on 16 projectile weapons, 15 from ice patches in southwest Yukon and one from the Selwyn Mountains, Northwest Territories. The objects selected for analysis cover much of the Holocene, with radiocarbon dates from 8103 to 170 cal. yr. BP and represent both throwing-dart and bow-and-arrow technology. The goal of the study was to identify the residues associated with hafting and to determine if patterns of material use exist. The residues were analyzed using a combination of analytical techniques: Fourier transform infrared spectroscopy (FTIR), gas chromatography–mass spectrometry (GC–MS), Raman spectroscopy, scanning electron microscopy–energy dispersive spectrometry (SEM–EDS) and polarized light microscopy (PLM). Hafting adhesive residues were found on nine objects that relate to throwing-dart technology and on two objects related to bow-and-arrow technology. In all cases where adhesive was found, the projectiles included chipped stone components. All adhesives, regardless of age, were found to be conifer resin, more specifically identified as spruce ( Picea sp.). While the majority of adhesives were relatively pure, homogeneous spruce resin, in the case of three stone dart points, the spruce resin was intentionally mixed with red ochre to produce a compound adhesive. A fourth stone dart point showed the use of spruce “callus” resin, a type of resin produced during wound closure on the surface of the tree, which has a unique chemical signature.
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publication
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[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Culture, cultural heritage and creativity"
]
] |
W2043695933
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Corporate social responsibility influences, employee commitment and organizational performance
|
Research on corporate social responsibility (CSR) majorly describes its effects on corporate financial performance or consumers’ behavior towards CSR. Relatively few studies have focused employee’s sentiments towards CSR. This study analyzes the multifaceted influence of CSR on employee’s organizational commitment and organizational performance. The study uses exploratory approach; primary data is collected from 371 professionals working in different sectors of Pakistan. The study uses structural equation model (SEM) technique to test the hypotheses. The study found significantly positive relationship between CSR actions and employee organizational commitment, CSR and organizational performance and employee organizational commitment and organizational performance. The study discusses important implications regarding uses of CSR for enhancing employee’s organizational commitment and improving organizational performance.
Key words: Corporate social responsibility, employee job satisfaction, organizational commitment, Pakistan.
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publication
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[
[]
] |
[
[]
] |
W2157723028
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Enhanced data management techniques for real time logistics planning and scheduling
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The EU faces the challenge to maintain and increase its economic growth and cope with the problem of freight transport efficiency in Europe. Integration of transport volumes and modes, better use of capacity, flexibility, resource efficiency and cooperation between all actors along the logistic chain are required.
Aligned with the European policies and the ALICE roadmap, LOGISTAR objective is to allow effective planning and optimizing of transport operations in the supply chain by taking advantage of horizontal collaboration, relying on the increasingly real-time data gathered from the interconnected environment. For this, a real-time decision making tool and a real-time visualization tool of freight transport will be developed, with the purpose of delivering information and services to the various agents involved in the logistic supply chain, i.e. freight transport operators, their clients, industries and other stakeholders such as warehouse or infrastructure managers.
LOGISTAR will address several advances beyond the State of the Art in the interdisciplinary field of the smart algorithms for data processing: Artificial Intelligence focussed onr prediction, parallel hybrid metaheuristics for optimization, automated negotiation techniques, and constraint satisfaction problem solving techniques. The resulting platform will outperform other market products and services such as Freight Exchange Systems, Collaborative Platforms, Transport Control Towers or Routing Systems.
LOGISTARS involves RTD organisations (DEUSTO, UCC, CSIC), technology developers (DNET, SWC), consultancy firms (MDST, PRESTON), ICT services developers (SAG, DBH, GENEGIS) and stakeholders from different stages of the supply chain (AHLERS, ZAILOG, NESTLÉ, PLADIS, CODOGNOTTO).
The duration of the project is estimated to be 36 months and has an approximate budget of 5 million euros.
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project/european
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[
[
"Digital, Industry and Space"
]
] |
[
[
"Artificial intelligence and robotics",
"Net-zero and less polluting Industries",
"Key digital technologies",
"Manufacturing technologies",
"Advanced computing and big data"
]
] |
224496
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TIE BAR FOR TWO POLE SWITCHING DEVICE
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A multipole switching device for selectively switching electrical power from an electrical power source to a load circuit comprises a first control device comprising a housing, an electromechanical actuator in the housing including a movable plunger (530), and an electrical switch in the housing operated by the plunger. A second control device comprises a housing mountable adjacent the first control device, an electromechanical actuator in the housing including a movable plunger (532), and an electrical switch in the housing operated by the plunger. A tie linkage (534) mechanically ties the first control device plunger (530) to the second control device plunger (532).
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patent
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[
[
"Digital, Industry and Space"
]
] |
[
[
"Manufacturing technologies"
]
] |
US 2007/0023401 W
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FÜHRUNG IM FOKUS
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Die Umsetzung des FOCUS LIGHT-Projekts wird direkt zur Steigerung der Wettbewerbsfähigkeit führen und das Exportpotenzial von Skale FOCUS AD durch die Einführung und Implementierung von IKT-basierten Software-Management- und Ressourcenmanagementsystemen, Produkt-/Dienstentwicklungsprozessen und Kerngeschäftsprozessen sowie die Einführung eines Umweltmanagementsystems nach ISO 14001 freisetzen.Der erwartete Beitrag des Projekts steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz des Unternehmens, der Steigerung der Produktivität, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation.In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation.In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation. In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation.In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz des Unternehmens in der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation.In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der Marktpräsenz des Unternehmens in der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation. In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt ist in direktem Zusammenhang mit der Verbesserung der Marktpräsenz des Unternehmens in der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts der Organisation.In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt ist in direktem Zusammenhang mit der Verbesserung der Marktpräsenz des Unternehmens in der Unternehmenspräsenz, der Optimierung der Kosten und der Steigerung des Mehrwerts auf allen Ebenen der Organisation. In diesem Zusammenhang sieht das Projekt die Umsetzung der folgenden Kernaktivitäten vor:1) Das Projekt steht in direktem Zusammenhang mit der Verbesserung der
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project/regional
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Net-zero and less polluting Industries",
"Manufacturing technologies",
"Key digital technologies"
]
] |
Q3903544
|
Building the case for automated building energy management
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Energy consumption in buildings comprises a significant fraction of total worldwide energy consumption and is strongly influenced by occupant behavior. To explore the quantitative effect of particular occupant actions on building energy consumption, we have evaluated eight energy-saving behaviors, as well as the of an in-home display (IHD), in 10 homes over the course of ten weeks. The results showed maximum savings ranging from 0%-20% attributed to the IHD, indicating that real-time feedback combined with actionable suggestions can motivate substantial conservation. By examining the data along with pre and post-experiment surveys, we conclude that automation is necessary to ease the more tedious tasks such as unplug when not in use and unplug the TV, where fewer than half of the highly capable and motivated participants performed the actions.
|
publication
|
[
[
"Climate, Energy and Mobility",
"Digital, Industry and Space"
]
] |
[
[
"Buildings and industrial facilities in energy transition",
"Energy systems and grids"
]
] |
W2062189828
|
Impact of gently dipping discontinuities on basement aquifer recharge: An example from Ploemeur (Brittany, France)
|
Classically, geological surveys of water resources in hard-rock aquifers are made from aerial photographs or geophysical techniques that basically permit to detect vertical features. On the other hand, aquifers only linked to vertical structures are very limited in space and offer in most cases very poor water resources. In the present case, we do show that an outstanding aquifer in Brittany is linked to a geological context associated with low-angle faults possibly directly connected with vertical feeders. In particular, we show through a high-resolution gravimetric survey that the highly fractured contact between granite and micaschists, which constitutes the main path for groundwater flow, is a gently dipping structure. Combined gravimetric, magnetic and geological data allowed us to establish the overall aquifer geometry by running a three-dimensional forward model. In addition, details about the shape of the contact have been obtained using an iterative scheme based on the method of Oldenburg (1974). The gravimetric model confirms the presence of sub-vertical faults that may constitute important drains for the aquifer recharge. Thus, the geological context associated with exceptional water resources for this crystalline aquifer is characterized by a sub-horizontal to gently dipping contact between granite and micaschists. Only such a geological context can allow sufficient recharge to provide the main water supply for a town of 18,000 inhabitants at an average rate of about a billion of cubic meter per year since 1991. Thus, instead of looking for possible vertical structures like in classical hard-rock hydrogeology, it appears much more efficient to detect sub-horizontal permeable fractures and faults for providing consistent water resources.
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publication
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[
[
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Seas, oceans and inland waters",
"Environmental observation"
]
] |
W2000869152
|
FPGA Development Phases
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The purpose of this chapter is to discuss the basic FPGA architecture and introduce the five Field Programmable Gate Array (FPGA) development phases. Topics dealt with are also the basic FPGA capabilities and Altera and Xilinx FPGA architecture. The layout of the generic FPGA architecture and I/O interfaces and some I/O standards has been given. Comparisons of the Altera and Xilinx I/O interface sections have been shown extensively with the Basic Logic Building Blocks of Xilinx and the series of Altera being discussed. Ability to Interconnect, Programmable Logic Device Options, advantages of using an IP core or function have been briefly dealt with. The chapter ends with the advice for the users to divide the tasks of developing FPGA designs into smaller phases of design, synthesis, simulation, implementation, and programming.
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publication
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Key digital technologies",
"Advanced computing and big data"
]
] |
W938986225
|
Features extraction in anterior and posterior cruciate ligaments analysis
|
The main aim of this research is finding the feature vectors of the anterior and posterior cruciate ligaments (ACL and PCL). These feature vectors have to clearly define the ligaments structure and make it easier to diagnose them. Extraction of feature vectors is obtained by analysis of both anterior and posterior cruciate ligaments. This procedure is performed after the extraction process of both ligaments. In the first stage in order to reduce the area of analysis a region of interest including cruciate ligaments (CL) is outlined in order to reduce the area of analysis. In this case, the fuzzy C-means algorithm with median modification helping to reduce blurred edges has been implemented. After finding the region of interest (ROI), the fuzzy connectedness procedure is performed. This procedure permits to extract the anterior and posterior cruciate ligament structures. In the last stage, on the basis of the extracted anterior and posterior cruciate ligament structures, 3-dimensional models of the anterior and posterior cruciate ligament are built and the feature vectors created. This methodology has been implemented in MATLAB and tested on clinical T1-weighted magnetic resonance imaging (MRI) slices of the knee joint. The 3D display is based on the Visualization Toolkit (VTK).
|
publication
|
[
[
"Health",
"Digital, Industry and Space"
]
] |
[
[
"Tools, technologies and digital solutions for health and care, including personalised medicine"
]
] |
W2053796854
|
High-Flux synchrotron alternatives driven by powerful long-wavelength fiber lasers
|
Lasers, and in particular ultrafast lasers, are an enabling technology for many applications, with the particularity that they can emit high-powers and are tabletop at the same time. These characteristics have made intense laser radiation widely available, which has decisively contributed to the advancement of many fields. However, the spectral coverage of lasers is limited and, thus, there are many applications that can only be addressed with other sources such as synchrotrons. Unfortunately, synchrotrons have two strong disadvantages: they are very large facilities with restricted user access and are extremely expensive. This is seriously hampering the widespread use of this radiation and, with it, the progress and development of many fields. Since a direct (i.e. a laser-based), high-power emission of coherent light with a wavelength coverage comparable to that of a synchrotron is impossible, nonlinear frequency conversion driven by a high-power solid-state laser seems to be the most elegant solution to achieve a high photon flux in important spectral regions such as the mid-infrared, the THz- and the soft-X-ray range. Most remarkably, frequency conversion into these spectral regions would strongly benefit from a longer driving laser wavelength than the standard Titanium:Sapphire or Ytterbium-based near-infrared emission. On top of that, the shift of the emission to longer wavelengths can unleash a hidden performance scaling potential of ultrafast fiber lasers, as nonlinear and thermal limitations scale favorably. The goals of the project SALT are twofold. First, it targets a revolution in the performance level of ultrafast lasers by unlocking the potential of Thulium-doped fiber lasers. Second, it aims at demonstrating new realms of flux in selected wavelength regions by frequency-converting these high-power 2µm sources. This will pave the way for frontier applications allowing for seminal discoveries and breakthroughs.
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project/european
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[
[
"Digital, Industry and Space"
]
] |
[
[
"Emerging enabling technologies"
]
] |
1261450
|
A pervasive framework for real-time activity patterns of mobile users
|
Given the rise of ubiquitous computing and communication devices like biosensors, smart watch, and smartphones, real-time online systems can provide users with a wide range of supports including monitoring daily activities and retrieving of personal data. User activity pattern can give an abstraction and summarization about physical behavior for certain group of people. However, one of the biggest challenges in this topic that we are facing today is the big data problem associated with large, complex, and dynamic data. In addition, as the demand for the integration and analysis of dynamic data as well as static historical data from different sources has been growing steadily, smartphones with limited capacity and computing abilities can hardly manage and process such a huge task. To address these above issues, a new framework has to be used to assist in the process, analysis, and integration of big data for a mobile platform. In this paper, I propose a distributed cloud based pervasive framework to help do complicated computing for a mobile platform. The framework has the ability to collect, process, analyze, and integrate different types of data from different sources by using state-of-the-art technologies. The purpose of this framework is to provide an intelligent and efficient approach to analyze and combine new incoming data with historical data to build and refine a solid user activity pattern.
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publication
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[
[
"Digital, Industry and Space"
]
] |
[
[
"Key digital technologies",
"Advanced computing and big data",
"Emerging enabling technologies",
"Artificial intelligence and robotics"
]
] |
W1525467295
|
Ultrastructural and molecular study of the microsporidian<i>Toguebayea baccigeri</i>n. gen., n. sp., a hyperparasite of the digenean trematode<i>Bacciger israelensis</i>(Faustulidae), a parasite of<i>Boops boops</i>(Teleostei, Sparidae)
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A new microsporidian Toguebayea baccigeri n. gen., n. sp., hyperparasite of Bacciger israelensis (Digenea, Faustulidae), parasite of Boops boops (Teleostei, Sparidae) is described by means of transmission electron microscopy. The phylogenetic analysis, based on the SSU rDNA gene, places the new species in the clade containing mainly crustacean-infecting microsporidia of the genus Cucumispora, within superclade V (Marinosporidia) sensu Vossbrinck et al., 2014. Mature spores of T. baccigeri are ovoid, uninucleated and measure 2.5 × 1.4 μm. The number of coils of the polar tube is 8-10. The polaroplast is composed of an external lamellar part and an internal vesicular or granular part. The main differences that distinguish the new genus and new species from the closely related microsporidia include hyperparasitism in a digenean host infecting a marine fish, the geographic distribution (coast of Tunisia), presence of one nucleus at all developmental stages, disporoblastic sporogony, and the absence of sporophorous vacuoles.Étude ultrastructurale et moléculaire de la microsporidie Toguebayea baccigeri n. gen., n. sp., hyperparasite du trématode digène Bacciger israelensis (Faustulidae), parasite de Boops boops (Teleostei, Sparidae).Une nouvelle microsporidie Toguebayea baccigeri n. gen., n. sp., hyperparasite de Bacciger israelensis (Digenea, Faustulidae), parasite de Boops boops (Teleostei, Sparidae) est décrite en microscopie électronique à transmission. L’analyse phylogénétique, basée sur l’étude du gène SSU rDNA, place la nouvelle espèce dans le clade qui contient notamment les microsporidies parasites de crustacés du genre Cucumispora, dans le superclade V (Marinosporidia) sensu Vossbrinck et al, 2014. Les spores mûres de T. baccigeri sont ovoïdes, uninucléées et mesurent 2,5 × 1,4 μm. Le nombre de tours de spire décrits par le tube polaire est de 8 à 10. Le polaroplaste est composé d’une partie externe lamellaire et d’une partie interne vésiculeuse ou granuleuse. Les principales différences entre le nouveau genre et la nouvelle espèce et les microsporidies les plus proches sont : l’hyperparasitisme d’un digène parasite d’un poisson marin, la localisation géographique (côtes de la Tunisie), et certains aspects du développement, notamment la présence d’un seul noyau à tous les stades de développement, la sporogonie disporoblastique et l’absence de vacuoles sporophores.
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publication
|
[
[
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Seas, oceans and inland waters",
"Biodiversity and natural resources"
]
] |
W4210510432
|
An easy-handling compound saw
|
The present invention relates to a compound saw which may be used as a mitre saw or as a table saw, in particular, an easy-handling saw of which the movable legs (308) may be used as handles. The base supporting the saw blade unit comprises a left side frame (32), a right side frame (31), and four independent movable legs (308) also acting as handles. Two sets of leg orientation devices are respectively disposed at the lower end of the left and right side frames, and each set of leg orientation devices respectively includes a vertical orientation slot which extends approximately vertically and a horizontal orientation slot which extends approximately horizontally. The upper ends of the movable legs may be connected to the leg orientation devices by movable locking mechanisms (311) and the movable legs may be restricted inside the vertical orientation slots or the horizontal orientation slots by means of the movable locking mechanisms. It has characteristics such as providing movable legs also acting as handles, light weight, and easy handling, etc, and it solves the problem of awkward, inconvenient handling due to the structure of conventional compound saws.
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patent
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[
[
"Digital, Industry and Space"
]
] |
[
[
"Manufacturing technologies"
]
] |
EP 07103785 A
|
Preliminary investigation on vectors of mosquito-borne diseases in Yiwu,Zhejiang
|
Objective To identify the major vectors of mosquito-borne diseases and their geographic distribution after the outbreak of dengue fever(DF) in Yiwu,providing basis for further prevention and control.Methods Light traps and dippers were used to collect mosquito adults and larvae,respectively,based on random sampling.Results At least 8 species in 4 genera belonging to 2 subfamilies were found in the region.Culex pipiens pollens coquillett was the dominant species found in 234 villages and 13 towns.Although there were few Aedes albopictus(Skuse) and other species collected from the traps,it was the only vector of DF in Yiwu that distributed in 10 towns and 18 villages,a result of the breeding place survey on mosquito larvae. Ae.albopictus larvae accounted for the highest proportion(51.7%) of the mosquito population,followed by Cx.tritaeniorhynchus, while other species including Cx.mimulus were limited.Conclusion In view of the widely distributed vectors of mosquito-borne diseases in Yiwu and regional concentration of high density,breeding sites should be eliminated to cut off the primary transmission route of vector-borne diseases in order to lay a sound foundation for further prevention and control.
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publication
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[
[
"Health",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Environmental and social health determinants",
"Infectious diseases, including poverty-related and neglected diseases"
]
] |
W2363123551
|
The JCST trainee survey: highlights of the first year's results
|
In July 2010, the Joint Commitee on Surgical Training (JCST) launched a review of its quality assurance functions, which included the development of a new survey specific to surgical trainees. The survey was developed in conjunction with the Confederation of Postgraduate Schools of Surgery and aimed to provide detailed information on the quality of surgical training in the UK and to standardise the information from the different schools of surgery, thereby allowing some comparison between training schemes and units. A 20-question survey was developed for all surgical specialties, while a more detailed survey with questions relating to curriculum delivery was piloted in core surgical training and paediatric surgery.
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publication
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[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[]
] |
W2006001086
|
Estudio geológico integrado de la formación mesa al sur del lote I en un contexto regional - Cuenca Talara
|
This thesis is to obtain Professional Engineer Geologist title, it is a study about Mesa Formation at south of block 1 within regional context of the Talara Basin, Department of Piura in Peru NO. The subsurface sedimentary column comprises approximately 9,000 meters of clastic sedimentary rocks covering from the Middle Cretaceous to Tertiary Superior that lie on a Base of Paleozoic metamorphic rocks.
This work is done at south of Block I in Talara Basin at Northwest Peru for Mesa Formation (Lower Paleocene) in order to obtain a better technical understanding of the geological formation, with the consequence of a notary improved oil production. For this study were used different studies like: Coronas, drill cuttings, and thin sections of electrical records recently drilled wells in the region. From 2012, after applying the studies in the extracted cores, production wells is becoming attractive for that reason the number of wells per year increases from 3 to 12, with main objective Mesa Formation
In the curve of cumulative production of Mesa Formation could see the key moments in time where production improves as a result of studies efforts.
Until the date of termination of contract GMP has a minimum amount of reserves of recoverable oil in the order of 611 MMbls in structural blocks not exploited today by Mesa Formation (In Mega I block up developing). With this amount of reserves at south of block I and considering drainage hole can be drilled at least 28 profitable oil wells in the Mesa Formation. Considering average price of a barrel oil of $ 80, then the profits would be an estimated of $ 48.9 MMU.
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publication
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[
[
"Digital, Industry and Space"
]
] |
[
[]
] |
W2552844361
|
Woven garment fabric
|
The woven fabric has warps of cladded yarns, with an elastane core and a mantle of polyamide in a thickness of 50-120 dtex. The wefts are of polyester, with a thickness of <= 60 dtex, pref. with 700-900 twists/m. The warps and wefts are dyed simultaneously using the same, different or contrast colors without damage to the elastane material. The warps have a pref. thickness of 70-100 dtex, or 50-80 dtex. The wefts have a pref. thickness of 45-55 dtex, or 20-30 dtex. The wefts are multi-lobed with a silky luster. The fabric is composed of 35-50 warps/cm and 25-40 wefts/cm, or 35-60 warps/cm and 32-43 wefts/cm.
|
patent
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Advanced Materials",
"Manufacturing technologies"
]
] |
FR 9716730 A
|
Sports Architecture Structure Stress Characteristics Analysis
|
In the sports architectural form creation, structure technology plays an important role, it is the ideal form of guarantee, elements and form, structure and technology as a method of design, is the factor most architects consider first in sports in architectural creation. Technology of building structure technology as the field of material production, the aesthetic features of its shape becomes the main expression of sports architecture aesthetics, aesthetic psychological effects caused by the people. Especially in large span structure system because of its giant scale and exaggerated shapes, people will lose their normal in the presence of mental judgment scale, often by its magnificent momentum of admiration, moved by the building architectural image and space atmosphere. In the sports building design, construction technical support on architectural forms and form depends on the structure technology is beyond doubt, shaping the spatial image mainly depends on the correct expression of shape.
|
publication
|
[
[
"Culture, Creativity and Inclusive Society",
"Digital, Industry and Space"
]
] |
[
[
"Key digital technologies",
"Advanced Materials",
"Manufacturing technologies"
]
] |
W2040961354
|
Strengthening innovation and competitiveness of dairy enterprises through Mobile Laboratories of quality control
|
The project aims to work with the entire dairy chain from the producers to the consumers, by introducing innovation technology in farming and cheese processing in order to standardize the Ionian and Apulian dairy products with the check of milk and cheese quality. In particular, the project will provide technical assistance to farmers by developing two mobile laboratories in Puglia and Ionian Islands that will enhance the cheese safety and quality level. The projects will involve local producers raisers and businessmen to facilitate commercial exchanges, especially women & young people to create conditions for new qualified jobs as opportunities.
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project/regional
|
[
[
"Culture, Creativity and Inclusive Society",
"Digital, Industry and Space",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Circular systems",
"Manufacturing technologies"
]
] |
interreg_2438
|
Mud-brick composition, archeological phasing and pre-planning in Iron Age structures: Tel ‘Eton (Israel) as a test-case
|
The eighth century BCE city at Tel ‘Eton (Israel) was destroyed by the Assyrian army, probably during Sennacherib’s campaign of 701. Building 101, sealed within the heavy conflagration caused by this destruction, was uncovered almost in its entirety on the top of the mound. From the beginning, it was apparent that the structure had two major building phases, and while its initial construction was of high quality, later additions were much inferior. Analyses of mud-brick walls for firing temperatures, texture, carbonate content, color, and dimensions approved the observation regarding the differences between the two phases, but consistently pointed out that one wall, initially attributed to the first phase, was analytically different, comprising an intermediate phase. This conclusion not only altered our understanding of the building construction, adding heretofore unknown building phase, but also gave us insights into the pre-planning of Building 101, indicating that some rooms had originally two doorways. Such a configuration allowed easy subdivision of spaces according to needs, without harming the overall structural stability. Differences in inner division of similar Iron Age houses were identified in the past and were attributed to differences in the life cycles of families. The evidence from Tel ‘Eton suggests that such future changes were taken into considerations when the structures were built.
|
publication
|
[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations",
"Culture, cultural heritage and creativity"
]
] |
W2464935267
|
Advanced analytics platform for stroke patients rehabilitation
|
Annually, 16 million people worldwide suffer a stroke. From these, approximately 6.5 millions are left with some degree of physical impairment that will require long-term intensive and effective motor rehabilitation programs.
Current traditional rehabilitation services are costly and highly dependent on (scarce) specialized human resources
At SWORD Health we believe that the solution for this problem is in the wise combination of novel neuroscience-driven therapeutic methods with effective technologies that facilitate the dissemination of care and the use of all the knowledge produced in the rehabilitation of a large network of patients. Pursuing this vision, we have developed an innovative system that allows the sustainable delivery of a more efficient motor rehabilitation to stroke patients, providing a rich source of data for clinicians and decision makers.
The SWORD system was specifically designed to be used by the patient at the hospital or at home, with little or no supervision, extending the therapeutic footprint and empowering the patient with his rehabilitation. The proposed system enables patients to accelerate their recovery with a more intensive and a higher quality therapy. At the same time, SWORD incorporates data mining algorithms specifically designed so that clinicians get continuous access to valuable data and advanced analytics, in order to coordinate teams, improve care, accelerate recovery and reduce time to achieve functional outcomes. For rehabilitation centres, the SWORD system allows for a higher profit margin per therapy unit through a more efficient allocation of specialized human resources.
The SWORD project falls under the scope of the Call ICT-37-2014 - topic: Open Disruptive Innovation Scheme. This is because the present project focus on an early-stage, high risk, innovative SME proposing an innovative ICT system that reinvents and ultimately disrupt the motor rehabilitation industry.
|
project/european
|
[
[
"Health",
"Digital, Industry and Space"
]
] |
[
[
"Non-communicable and rare diseases",
"Health throughout the life course",
"Healthcare systems",
"Tools, technologies and digital solutions for health and care, including personalised medicine"
]
] |
174309
|
Simultaneous localization and mapping for augmented reality
|
The PoC Project SLAM4AR is focused on developing technological foundations for advanced augmented reality (AR) applications on smartphones. According to a recent study of Hampleton & Partners, the market value for AR applications is expected to break the $170 billion barrier by 2022. And a significant share of this market value will come from smartphone applications. In the PoC project SLAM4AR, we will build up on state-of-the-art algorithms for visual Simultaneous Localization and Mapping (SLAM) that we developed in the ERC CoG “3D Reloaded”. These algorithms allow one to recover the motion of a camera and a 3D reconstruction of the observed environment at unprecedented precision, robustness and large-scale capability (among existing real-time capable algorithms). We will reformulate and streamline these algorithms so that they can run on smartphones. They will leverage the smartphone’s camera and inertial sensor in order to compute in real-time both the location of the phone and a 3D map of the environment. In several AR applications, we will demonstrate that our algorithms with their superior precision and robustness serve as a key enabler for advanced AR technology. For example, we can perform object insertion (beyond Pokemon Go) in a way that dynamic objects interact more naturally and faithfully with a complex 3D environment – they accurately sit on chairs or tables, or they convincingly roll down slopes, etc. This will enable numerous AR applications such as teaching medical students about the 3D location of bones and inner organs, training novice car mechanics in the inner structures of a motor. Or navigating tourists to a desired location in a museum or a church. There is a rapidly growing market for AR applications on phones and we are convinced that our smartphone-based visual SLAM technology will serve as a key enabler.
|
project/european
|
[
[
"Culture, Creativity and Inclusive Society",
"Digital, Industry and Space"
]
] |
[
[
"Key digital technologies",
"Artificial intelligence and robotics",
"Emerging enabling technologies",
"Next generation internet"
]
] |
2729297
|
Model catalysts for understanding oxygen evolution reaction activity
|
Hydrogen is considered essential to reach the European Green Deal and Europe´s clean energy transition. Nowadays, most hydrogen is produced by reforming of fossil fuels. Electrochemical water electrolysis using renewable sources as energy input represents a cleaner way than reforming of fuels to create hydrogen. However, water electrolysis will only be feasible if stable, affordable and effective catalysts for oxygen evolution reaction (OER) are discovered. The research objective of this project is to explore the catalytic activity in OER of Earth abundant transition metal oxides to gain fundamental understanding on the nature of the active sites. To this effect, ordered thin films will be grown, aiming to discover the most active formulations and facets of the crystal structure. This project will be performed at the Fritz-Haber-Institut der Max-Planck-Gesellschaft (MPG), in the department of Interface Science lead by Prof. Roldán Cuenya. MPG was ranked as the third top institution according to the Nature Index 2019. I will work with Dr. Kuhlenbeck, an expert in the surface science field. Merging of his experience in growing thin films with the my background in electrochemical processes is key for the success of the project. During the two years of the project, I will be involved in the dissemination of the results to Academia and the general public through participation in conferences, publication of articles and outreach activities. An individual Career Development Plan, outlined and reviewed by Dr. Kuhlenbeck and Prof. Roldán Cuenya, will be used to monitor the research maturity obtained during the project.
|
project/european
|
[
[
"Climate, Energy and Mobility",
"Digital, Industry and Space"
]
] |
[
[
"Energy supply",
"Energy systems and grids"
]
] |
650500
|
Heritage in the Atlantic Area: sustainability of the urban world heritage sites
|
The urban World Heritage sites (WHS) represent an important cultural value in the context of the Atlantic Area. The AtlaS.WH project intends to create a network of urban WHS, by addressing common challenges related to the protection of their identity, while enhancing their cultural assets, in order to stimulate heritage-led economic and cultural development.
AtlaS.WH will be an important step for their preservation, enhancement and sustainability. The main objectives are:
i) To address, within a common methodology, the main challenges that each WHS is facing, including tourism, gentrification, risk management, climate change, energy efficiency, among others;
ii) To develop strategies and public policies for the sustainability of urban WHS;
iii) To create governance models, open to the community, integrated and participative;
iv) To develop management tools, recommendation guides, assessment and measurement models;
v) To create a long-lasting network of WHS, in order to disseminate best practices and to reinforce cooperation.
The main result will be the Sustainability Plans for each WHS, by implementing an integrated and participative management and monitoring model, which arises from the common construction of a methodology and the exchange of know-how and best practices.
|
project/regional
|
[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations",
"Culture, cultural heritage and creativity"
]
] |
interreg_383
|
Degradation of ozone-depleting methyl halides in the troposphere characterized by isotopes
|
The stratospheric ozone layer is an important shield to protect life on earth. Most of the short-waved UVB radiation is absorbed which otherwise would cause skin cancer and genetic damage. Destruction of the ozone layer by halogen radicals was discovered in the 1970s and consequently production of many halogenated compounds was curtailed. Methyl chloride (CH3Cl) and methyl bromide (CH3Br), important contributors of halogens in the stratosphere, are emitted by both natural and anthropogenic sources but significant gaps remain in the calculated atmospheric budget due to uncertainties concerning formation mechanisms and/or overestimation of degrada-tion processes. In this study a conceptual framework will be developed to apply innovative multi-element isotope analysis (2H, 13C, 81Br, 37Cl) for delineating sources and sinks of methyl halides, reducing the budget uncertainties and discrepancies. The specific aim is to isotopically identify and characterize oxidation of methyl halides by hydroxyl radicals, the main degradation process, both to understand the fate of these important pollutants in the environment but foremost to resolve the impact on any future isotope based approach for source apportionment. The results of this project will also have broader impact as the information and interpretational frameworks developed will be applicable to research on other environmentally relevant gases, e.g. greenhouse gases. Returning to the EU the applicant will expand his own doctoral experiences obtained in Sweden, and bring to the proposed work his innovative experiences and techniques on CFCs developed through his current post-doctoral research in Canada. Therewith this project not only counteracts brain drain but, based on the unique combination of expertise of all contributors, the applicant will be able to bring his past and current research skills and insight to bear to start developing his own research career within the proposed field.
|
project/european
|
[
[
"Climate, Energy and Mobility",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Climate science and solutions"
]
] |
171024
|
The role of genetic redundancy in adaptive evolution of efflux pumps
|
In genetic redundancy, multiple genes in a genome perform the same or similar function. Although redundancy is widespread across the tree of life, its evolutionary origins are not entirely understood. Genetic redundancy may provide a fitness benefit during evolution by increasing gene dosage and protecting critical genes from deleterious mutations. These fitness effects have been confirmed experimentally, but their long-term consequences for evolution have not been tested. In this study, I will manipulate the genomic content of efflux pump genes in E. coli and test the effect of their redundancy using directed evolution of proteins. By evolving the multidrug efflux pump AcrAB at different levels of redundancy, I will determine how the presence of other genes with overlapping drug-efflux activities affects adaptive evolution. I will compare evolutionary trajectories using comprehensive sequence and fitness analysis of the evolved efflux pump variants. This approach will provide a unique opportunity to directly test the role of genetic redundancy in evolution and help to understand why genetic redundancy is maintained in a genome.
|
project/european
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Emerging enabling technologies",
"Advanced Materials"
]
] |
640631
|
SCREEN RAKE
|
The invention relates to a screen rake (1) for removing solids from a flow of waste water, comprising a driveable belt screen (2) for placing in the flow of waste water, said belt screen having two side link chains. Screen or filter elements (3) consisting of perforated plates (24, 26) extend between said link chains. The inventive screen rake is characterised mainly in that all of the screen or filter elements (3) are arranged on the front (in the direction of movement) chain link bores (18) in such a way that they are mobile and in that the opposite part of the screen or filter elements (3) rests on the trailing shaft (19). The invention also relates to a method for operating the screen rake (1).
|
patent
|
[
[
"Digital, Industry and Space",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Net-zero and less polluting Industries",
"Circular systems",
"Manufacturing technologies"
]
] |
EP 9806941 W
|
Preliminary study on navigation development and comprehensive improvement of North Cannel
|
Based on a deep investigation on the history and present status of Jinghang Grand Canal,the feasibility of the navigation and comprehensive improvement of the river reach of the North Canal between Beiguan Sluice in Tongzhou Distrct of Beijing and Qujiadian Barrage Project in Beichen District of Tianjin is studied;in which the main technical difficulties of the navigation of the canal is analyzed,and then the technical schemes for the navigation with two ship-locks and four ship-locks are compared in accordance with the waterway classifications of both V and VI.Furthermore,an extensive study is made from the aspects such as the comprehensive utilization of water resources,flood control project,waterway regulation,sluice and bridge reconstruction,layout of wharf and pier,construction of landscape,water quality restoration,etc.It is recommended that a comprehensive improvement must be made on the navigation development of the canal,i.e.besides the consideration on the technical requirement of the navigation,the water transport culture of the canal with a history of nearly a thousand years must be inherited and continued,while the eco-environment suitable for living must be constructed as well.
|
publication
|
[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations",
"Culture, cultural heritage and creativity"
]
] |
W2348357152
|
Automata and power in the culture of machines of renaissance florence, milan and venice (1400-1600)
|
This interdisciplinary project aims to innovatively fill a gap in the fast-growing historiography on automata, focussing on the social, cultural and material history of these types of machines in Renaissance Italy. For the first time, AUTOREN will investigate the history of automata in the areas of Milan, Venice and Florence between 1400 and 1600. These three Northern Italian engineering traditions are among the most thriving early modern cultures of machines, and they have been researched for their seminal influences on the development of European useful machines: these are traditionally related to warfare, construction, hydraulic and industrial technologies and timekeeping. Surprisingly, the most elaborate mechanical achievements of Renaissance Italy did not belong to such a positivist idea of utility, but to those functions directed at animating a symbolic organism that conveyed a multi-layered intellectual message often undecipherable to our contemporary eye. AUTOREN will examine these other layers of the concept of mechanical utility in relation to philosophy, representation of power, knowledge-seeking activities, piety and marvel. Among these symbolic machines, for the first time, AUTOREN will comparatively explore state-funded mechanical projects such as cosmomorphic automata (planetary contrivances demonstrating the movements of all the heavenly bodies) and a surprisingly understudied group of still extant anthropomorphic automata (especially self-propelled spring-driven automata). Crafting a toolbox at the crossroads of archaeometry and the historiographies of philosophy, art, science and technology AUTOREN will be able to highlight overlooked Northern Italian contributions to technological innovation and trends in mechanical projects to European early modern culture of machines at the dawn of that long epistemological shift known as the Scientific Revolution.
|
project/european
|
[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations",
"Culture, cultural heritage and creativity"
]
] |
645578
|
Green advanced technologies for the retrofitting of masonry structures
|
Unreinforced masonry (URM) buildings constitute more than 70% of the existing building stock worldwide and make up the vast majority of the world’s cultural and architectural heritage. Although masonry has proven to be a highly versatile and durable construction material, much of the existing building stock in Europe and developing countries are non-engineered URM buildings, often built with weak materials and following poor construction practices. As a result, the majority of the existing building stock is in dire need of structural rehabilitation and strengthening. Traditional strengthening and rehabilitation techniques include grout or epoxy injections, crack stitching, surface overlays with mesh-reinforced concrete, chicken-wire or reinforced plaster, reinforced concrete jacketing as well as external/internal post tensioning. However, all of these techniques can affect significantly the dynamic response characteristics of the structure and can be costly, labour-intensive and highly obtrusive. In recent years, the use of advanced composite materials in civil engineering applications has increased exponentially, and the various retrofitting solutions that have been developed based on the implementation of these materials have proven to be very effective. However, the high performance of these advanced materials would not be effectively exploited on the less demanding masonry structures and the high material and installation costs would render them prohibitive in most European and developing countries. The proposed project aims to develop a novel strengthening solution that uses natural fibre meshes embedded in an inorganic lime-mortar matrix. The new system will provide a more sustainable and cost‐effective alternative and will provide a more reliable solution that can be engineered to meet the specific performance criteria of masonry buildings.
|
project/european
|
[
[
"Culture, Creativity and Inclusive Society",
"Digital, Industry and Space"
]
] |
[
[
"Circular systems",
"Advanced Materials",
"Manufacturing technologies"
]
] |
988908
|
Application Study of Edge Detection for Droplet in Laser Enhanced GMAW Welding
|
Ambient pressure has a certain inhibiting effect on underwater welding droplet transfer and the stability of welding process. Good droplet transfer of underwater welding plays an important role in improving repairing quality of underwater structures. As an additional droplet separating force, laser provides effective means in improving the welding quality. For quantitative analysis and comparison of laser enhanced effect on droplet transfer, a high-speed camera system to shoot the process of welding droplet transfer was designed and by adopting the frequency domain operation, a filter aiming at image processing of welding droplet was also designed to filter the ambient noise and diffraction fringe. Through edge detection algorithm, edges of droplet images were detected, and the size of droplet was computed accurately with welding wire as the reference. At last, droplets’ statues under different welding parameters were compared. The results show that the clear images of GMAW droplet separated from the noise background can be acquired, which makes the high-precision quantitative analysis of laser enhanced effect possible. All of the results lay a foundation for further test of laser enhanced hyperbaric underwater welding.
|
publication
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Artificial intelligence and robotics",
"Advanced Materials",
"Manufacturing technologies"
]
] |
W2157402728
|
Efficacy of Immediate and Delayed Cognitive and Physical Rest for Treatment of Sports-Related Concussion
|
To evaluate the efficacy of cognitive and physical rest for the treatment of concussion.High school and collegiate athletes (N = 49) underwent post-concussion evaluations between April 2010 and September 2011 and were prescribed at least 1 week of cognitive and physical rest. Participants were assigned to groups on the basis of the time elapsed between sustaining a concussion and the onset of rest (1-7 days, 8-30 days, 31+ days). Main outcome measures included Concussion Symptom Scale ratings and scores on the 4 composite indices of the Immediate Post-Concussion Assessment and Cognitive Testing measure, both before and following rest. Mixed-factorial design ANOVA were used to compare changes on the dependent measures within and between groups.Participants showed significantly improved performance on Immediate Post-Concussion Assessment and Cognitive Testing and decreased symptom reporting following prescribed cognitive and physical rest (P < .001), regardless of the time between concussion and onset of rest (P = .44).These preliminary data suggest that a period of cognitive and physical rest may be a useful means of treating concussion-related symptoms, whether applied soon after a concussion or weeks to months later.
|
publication
|
[
[
"Health"
]
] |
[
[
"Non-communicable and rare diseases",
"Health throughout the life course"
]
] |
W2011459700
|
A saturated map of common genetic variants associated with human height
|
Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40-50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes1. Here, using data from a genome-wide association study of 5.4 million individuals of diverse ancestries, we show that 12,111 independent SNPs that are significantly associated with height account for nearly all of the common SNP-based heritability. These SNPs are clustered within 7,209 non-overlapping genomic segments with a mean size of around 90 kb, covering about 21% of the genome. The density of independent associations varies across the genome and the regions of increased density are enriched for biologically relevant genes. In out-of-sample estimation and prediction, the 12,111 SNPs (or all SNPs in the HapMap 3 panel2) account for 40% (45%) of phenotypic variance in populations of European ancestry but only around 10-20% (14-24%) in populations of other ancestries. Effect sizes, associated regions and gene prioritization are similar across ancestries, indicating that reduced prediction accuracy is likely to be explained by linkage disequilibrium and differences in allele frequency within associated regions. Finally, we show that the relevant biological pathways are detectable with smaller sample sizes than are needed to implicate causal genes and variants. Overall, this study provides a comprehensive map of specific genomic regions that contain the vast majority of common height-associated variants. Although this map is saturated for populations of European ancestry, further research is needed to achieve equivalent saturation in other ancestries.
|
publication
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Key digital technologies",
"Advanced computing and big data"
]
] |
W4304698823
|
Capillary Imbibition of Gadolinium Halides into WS2 Nanotubes: a Molecular Dynamics View
|
The structure of the molten salts GdX3, where X denotes Cl, Br, or I, and the kinetics of their penetration into WS2 nanotubes were investigated using molecular dynamics simulations. The GdCl3 and GdBr3 melts are found to comprise an amorphous framework structure with substantial intermediate-range ordering, as manifested by pair distribution, and angle-resolved pair-pair distribution functions associated with cationic correlations. In contrast, the GdI3 melt is a liquid with short-range cationic ordering. These structural peculiarities cause dramatically different mobility of Gd cations among pure GdX3 melts and explain the relative difference in the capillary activity of WS2 nanotubes regarding the melts, as observed in preliminary experiments. Extended MD simulations of GdCl3 dissolved in molten KCl predict the total degradation of the GdCl3 framework structure below 40 mol %, although no essential uptake of Gd cations by the WS2 nanotube is observed, due to more progressive diffusion of K cations. Our theory suggests that, among the considered halides, only the GdI3 compound is suitable for Gd encapsulation into WS2 nanotubes employing the capillary technique.
|
publication
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Emerging enabling technologies",
"Advanced Materials"
]
] |
W2511370478
|
Support for SMEs affected by COVID-19
|
Co-financing of a hotel and catering facility, which is also a historical object. We have suffered tremendous financial losses as a result of COVID-19. It is a historic building that needs special attention. In order to continue to function and be accessible to customers, he needs support. The cost of maintaining the facility is very high. The crisis caused by Covid – 19 stands on the verge of bankruptcy.
|
project/regional
|
[
[
"Culture, Creativity and Inclusive Society",
"Civil Security for Society"
]
] |
[
[
"Social and economic transformations",
"Culture, cultural heritage and creativity"
]
] |
Q2697310
|
The Effect of Interest Rate, Inflation and Government Expenditure on Economic Growth in Indonesia Period of 2005- 2012
|
This study analyzed the effect of interest rates, inflation rates and government spending on economic growth in Indonesia during 2005 to 2012. By using the method of data analysis panel, overall the independent variables namely interest rate, inflation rate and government spending has a 99% influence on the dependent variable of economic growth. The results of this research is government spending has a positive significant to economic growth. It means that government spending has an effect on economic growth, according to Keynesian theory. Variable interest rate has a significant negative to economic growth, it means that the interest rate effect on economic growth. If the central bank decrease the interest rate, then the investment will be increase, and it means economic growth will also increase. While the rate of inflation also affect economic growth, inflation has a significant positive to economic growth, because the inflation rate in Indonesia is relatively low, it is below 10% and stable. Keywords: interest rate, inflation, government expenditure, economic growth
|
publication
|
[
[]
] |
[
[]
] |
W1510163937
|
The mechanism of sleep control through a sleep-active sleep-promoting neuron
|
Sleep is essential for human and animal life and is broadly conserved. The nervous system induces sleep through the activation of sleep-active sleep-promoting neurons but the key mechanisms of sleep control remain to be elucidated. Recent work from my lab showed that the C. elegans nervous system contains a single sleep-active sleep-promoting neuron, called RIS, which is GABAergic and peptidergic as is its vertebrate counterpart. C. elegans shows sleep behavior and allows the easy combination of behavioral assays with functional neural imaging and genetics. Here I propose to study the single neuron RIS as a highly simplified model of a sleep-active neuron. This is a unique and novel approach to sleep research and my expertise on sleep behavior in C. elegans puts me into a pole position to study sleep. I will elucidate the molecular mechanism of activation of sleep-active neurons, analyze the mechanism of homeostasis of sleep-active neurons, and determine the molecular mechanisms by which sleep-active neurons induce sleep in the nervous system. I will combine transcriptional profiling of sleep-active neurons with physiological assays such as functional neural imaging, genetic screening, optogenetics, and functional molecular analysis of mutants. Using the highly simplified C. elegans model, I will boost sleep research and gain mechanistic insight into the regulation of sleep behavior through sleep-active neurons. This will be the first time that sleep-active neurons have been dissected in this way and I expect to identify novel conserved molecular and circuitry mechanisms. This work should provide the basis for understanding the more complex systems that control sleep in vertebrates and for understanding human sleep disorders.
|
project/european
|
[
[
"Health",
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Health throughout the life course",
"Non-communicable and rare diseases"
]
] |
171939
|
SPACECRAFT, COATING AND METHOD
|
A spacecraft, for example a satellite, or a part thereof having a coating comprising a 2D material on an outer surface thereof is described. The 2D material comprises one or more elements, excluding C, N and S, in an amount of at least 50 at.%; and respective oxides of the one or more elements of the 2D material have a vapour pressure of at most 10 Pa at a temperature of 323 K.
|
patent
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Advanced Materials",
"Space, including Earth observation"
]
] |
EP 2021077192 W
|
Secondary bronchiolitis obliterans organizing pneumonia during treatment of chronic hepatitis C: role of pegylated interferon alfa-2a
|
The treatment of chronic hepatitis C has frequent side effects such as cytopenias and neuropsychiatric symptoms. However, pulmonary toxicity associated with interferon is rarely described. This paper describes the clinical case of a 67-year-old female patient with chronic hepatitis C who presented an acute onset of dry cough, dyspnoea, and fever 36 weeks after the use of pegylated interferon alfa-2a and ribavirin. The lung biopsy confirmed the diagnosis of a bronchiolitis obliterans organizing pneumonia (BOOP). Corticotherapy was initiated, with clinical and radiological improvement. This paper aims to advise physicians to this occasional, though severe, adverse event related to hepatitis C virus (HCV) treatment.
|
publication
|
[
[
"Health"
]
] |
[
[
"Non-communicable and rare diseases",
"Healthcare systems"
]
] |
W1999202406
|
SOSTEGNO ALLA LIQUIDITA' PER MICROIMPRESE COLPITE DALL'EMERGENZA COVID
|
SOSTEGNO ALLA LIQUIDITA' DELLE MICRO E PICCOLE IMPRESE DEI SETTORI COMMERCIO AL DETTAGLIO, SOMMINISTRAZIONE E SERVIZI ALLA PERSONA, LA CUI ATTIVITA' SIA STATA SOSPESA PER EFFETTO DEL DPCM 11 MARZO 2020
|
project/regional
|
[
[
"Civil Security for Society"
]
] |
[
[
"Protection and security",
"Disaster-resilient societies"
]
] |
Q4251952
|
Sound propagation in deep water with the presence of seamounts
|
Seamounts in deep water have significant effects on the sound propagation. However, the reconstruction of the broadband pulses behind a seamount is indeed challenging due to the complex environment. It seems worthy to investigate the effects of seamounts on sound propagation in deep water. An experiment was conducted in 2014 in the Southern China Sea to investigate sound propagation in an environment with and without seamounts. The effects of seamounts on sound propagation were analyzed by using the broadband signals from the two propagation tracks. Transmission losses (TLs) differences for propagation in the environments with and without seamount are observed. When seamount located in the first shadow zone, the TLs decrease up to 7 dB before the seamount due to reflection of the bathymetry. The convergence zone structures are destroyed by the direct blockage of seamount and TLs increase more than 30 dB behind the seamount. Abnormal TLs and pulse arrival structures are explained by using ray theory. The numerical TLs and pulse arrival structures can match with experimental results.
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publication
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Emerging enabling technologies",
"Advanced Materials",
"Space, including Earth observation"
]
] |
W2518321734
|
Unified Treatment of Ideal Fermi, Bose, and Classical Gases
|
We give a unified treatment of ideal Fermi, Bose, and classical gases for temperatures sufficiently large that energy levels can be treated as a quasi-continuous. Sums can be converted to integrals over a density of quantum states to evaluate thermodynamic functions. Pressure is equal to two-thirds of the energy density for all three gases. Relevant integrals can be represented by series expansions if the absolute activity is less than unity, which is always the case for bosons. For fermions, larger values of the absolute activity can be handled by an asymptotic expansion. Virial expansions for the pressure of these ideal gases are power series in the ratio of the actual concentration to the quantum concentration. For absolute activity less than unity, the deviation from ideal gas behavior is practically linear in that ratio, less pressure for bosons, and more for fermions. Formulae for the heat capacity of these gases at constant volume are calculated in terms of several integrals.
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publication
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[
[]
] |
[
[]
] |
W1941701029
|
Attesting neanderthal dwelling space use: effects of human occupations in the middle palaeolithic record of fumane cave
|
The debate over Neanderthal subsistence patterns and behavioural aspects is source of many discussions and scieThe debate over Neanderthal subsistence patterns and behavioural aspects is source of many discussions and scientific contributions. Research over the last ten years has produced new data on mobility, economic strategies and life-aspects of Neanderthals, that have changed and enriched the comprehension of the material record of these ancestors. The project entitled “Attesting Neanderthal Dwelling Space Use: effects of human occupations in the Middle Palaeolithic record of Fumane cave” (ANDSU) will address the identification of changes in Neanderthal subsistence patterns across the analysis of the late mousterian sequence of Fumane cave (44-47.6 ka cal BP) (Verona, Italy). ANDSU will overcome the traditional limits of scientific research through specific objectives: identify Neanderthal spatial patterns, site function, temporality (or not) of activity areas and hearths and lengths and number of occupation(s)/event(s). An integrated multidisciplinary research methodology that has never been proposed until today, will be useful to address the aforementioned objectives and enhance the state-of the-art. Based on bone refits, Spatial Archaeology, multivariate Statistic techniques and 3D modeling reconstruction the project emerge for its combined high-innovative methodologies. The experimentation of 3D scan of bones will provide an important step for the attempt to automatically, or semi-automatically refit of faunal assemblages. , would radically transform zooarchaeological research methods. On the base of these premises, ANDSU focuses on the crucial need to extend our knowledge about Middle Palaeolithic record and to understand the range of Neanderthal variability. Also, it is expected to open up new perspectives to know the life-ways of Fumane inhabitants and to understand their cultural relationships, compared with Neanderthal groups of other European regions.
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project/european
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[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Culture, cultural heritage and creativity"
]
] |
3738388
|
Advances in research on theories of the dark universe - inhomogeneity effects in relativistic cosmology
|
The project ARTHUS aims at determining the physical origin of Dark Energy: in addition to the energy sources of the standard model of cosmology, effective terms arise through spatially averaging inhomogeneous cosmological models in General Relativity. It has been demonstrated that these additional terms can play the role of Dark Energy on large scales (but they can also mimic Dark Matter on scales of mass accumulations). The underlying rationale is that fluctuations in the Universe generically couple to spatially averaged intrinsic properties of space, such as its averaged scalar curvature, thus changing the global evolution of the effective (spatially averaged) cosmological model. At present, we understand these so- called backreaction effects only qualitatively. The project ARTHUS is directed towards a conclusive quantitative evaluation of these effects by developing generic and non-perturbative relativistic models of structure formation, by statistically measuring the key-variables of the models in observations and in simulation data, and by reinterpreting observational results in light of the new models. It is to be emphasized that there is no doubt about the existence of backreaction effects; the question is whether they are even capable of getting rid of the dark sources (as some models discussed in the literature suggest), or whether their impact is substantially smaller. The project thus addresses an essential issue of current cosmological research: to find pertinent answers concerning the quantitative impact of inhomogeneity effects, a necessary, worldwide recognized step toward high-precision cosmology. If the project objectives are attained, the results will have a far-reaching impact on theoretical and observational cosmology, on the interpretation of astronomical experiments such as Planck and Euclid, as well as on a wide spectrum of particle physics theories and experiments.
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project/european
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[
[]
] |
[
[]
] |
220532
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A parametrization of a steady periodic solution of the Fourier equation to model soil temperature dynamics
|
In dry days the temperature of the upper soil layers presents a characteristic asymmetric periodic-like pattern with a minimum in the morning and a maximum in the afternoon. In view of estimating the conductive heat component of the surface energy balance, at local, basin, and global scales, in this study we use a periodic series solution of the Fourier equation to develop a simple procedure to accurately reconstruct the soil temperature and heat flux profiles. The method is based on weighting and phasing the Fourier harmonics by means of coefficients which do not depend on the soil thermal properties but only depend on the shape of the temperature boundary condition. The proposed coefficients can be regarded to as site independent and with good approximation universal. In order to calibrate and test the procedure, measurements of soil temperature, soil heat flux, and soil water content, collected during the CividatEX Experiment (summer 2012, summer 2013, and spring and summer 2014), in Italy, were used. The method accurately reproduced the temperature observations at three measurement depths within the upper 20 cm soil layer. Once assessed the soil thermal conductivity, the method proved to be effective also in reproducing the measured soil heat flux. The procedure was furthermore validated reconstructing with good results the soil temperature dynamics measured by an independent micrometeorological station in a different environment.
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publication
|
[
[
"Climate, Energy and Mobility",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Climate science and solutions",
"Energy systems and grids"
]
] |
W1861498428
|
' sensing skin' for monitoring-based maintenance of the transport infrastructure (senskin)
|
Structural Health Monitoring (SHM) is expected to play a predominant role in the management of the transport infrastructure. Yet, SHM techniques continue to rely on point-based, as opposed to spatial, sensing requiring a dense network of these point-sensors increasing considerably the monitoring cost. Additionally, commercially available, strain sensors cannot measure strains beyond 1% to 2% and, thus, are not able to provide an alarm for an imminent catastrophe.
SENSKIN aims to:
(a) develop a dielectric-elastomer and micro-electronics-based skin-like sensing solution for the structural monitoring of the transport infrastructure that will offer spatial sensing of reversible (repeated) strains in the range of 0.012% to more than 10%, that requires little power to operate, is easy to install on an irregular surface, is low cost compared to existing sensors, allows simple signal processing and includes the ability of self-monitoring and self-reporting.
(b) use the new and emerging technology of Delay Tolerant Network to secure that strain measurements acquired through the 'sensing skin' will reach the base station even under extreme environmental conditions and natural disaster events such as, high winds or an earthquake, where some communication networks could become inoperable.
(c) develop a Decision-Support-System for proactive condition-based structural intervention under operating loads and intervention after extreme events. It will be based on an accurate structural assessment based on input from the strain sensors in (a) above and will examine the life-cycle economic, social and environmental implications of the feasible rehabilitation options and the resilience of the infrastructure to future changes in traffic demand that these options offer.
(d) implement the above in the case of bridges and test, refine, evaluate and benchmark the monitoring system (integrated a and b) and package (integrated a, b and c) on actual bridges.
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project/european
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[
[
"Digital, Industry and Space",
"Civil Security for Society"
]
] |
[
[
"Emerging enabling technologies",
"Net-zero and less polluting Industries",
"Key digital technologies",
"Circular systems",
"Manufacturing technologies",
"Advanced Materials"
]
] |
172047
|
Progress in the Total Synthesis of Rocaglamide
|
The first cyclopenta[b]benzofuran derivative, rocaglamide, from Aglaia elliptifolia , was found to exhibit considerable insecticidal activities and excellent potential as a therapeutic agent candidate in cancer chemotherapy; the genus Aglaia has been subjected to further investigation. Both the structural complexity of rocaglamide and its significant activity make it an attractive synthetic target. Stereoselective synthesis of the dense substitution pattern of these targets is a formidable synthetic challenge: the molecules bear five contiguous stereocenters and cis aryl groups on adjacent carbons. In past years of effort, only a handful of completed total syntheses have been reported, evidence of the difficulties associated with the synthesis of rocaglate natural products. The advance on total synthesis of rocaglamide was mainly reviewed from intramolecular cyclization and biomimetic cycloaddition approach.
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publication
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[
[
"Health",
"Digital, Industry and Space"
]
] |
[
[
"Non-communicable and rare diseases"
]
] |
W1999884007
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Sense, science and the magic of food
|
The purpose of the SESAM - Sense, Science and the Magic of Food is to create interest among young people at school and among citizens about the role of science in society by using the call for food systems transformation that is created by the climate crisis as the science case. The SESAM is bringing school youth, citizens and scientists involved in the bioeconomy and in curricular studies together around one open and public event in September 2-4 2020. The SESAM aims to demonstrate how young people and citizens by working together with academia and science can contribute to solving some of the urgent and complex sustainability challenges across global to local scales and multiple domains facing societies. The SESAM will be built around the idea of live Young Minds Food Lab that will form the physical frame for the events. The Young Minds Food Lab has been tested in several contexts at science and food festival as a way to highlight the commitment and importance of young peoples solutions to societal challenges. It builds on the idea of creating 21st century skills in learning workshops where pupil are challenged to address some of most important food and bio-economy relevant SDG´’s. The YouMiLa functions at the same time as a catchy and attention creating backdrop for the activities at the SESAM. The YouMiLa acts as a temporary science centre and includes a number of specific learning stations all manned by groups of 2.4 pupils all coached by a science teacher. All learning stations are involves one or more specific science principles from biology, chemistry and/or physics as well as one or more digital principles such as Artificial Intelligence, Virtual and Augmented Reality, Robotics, Biometrics, Coding and Data Science.
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project/european
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[
[
"Culture, Creativity and Inclusive Society",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Social and economic transformations",
"Culture, cultural heritage and creativity"
]
] |
3735848
|
PROCESS FOR REFINING FIBER AND DERIVING CHEMICAL CO-PRODUCTS FROM BIOMASS
|
The invention herein disclosed and claimed is a process for refining fiber from lignocellulosic biomass. The process provides refined fiber and agriculturally amenable co-products, with a virtually waste-free systems design.
|
patent
|
[
[
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Circular systems",
"Bio-based innovation systems in the bioeconomy"
]
] |
US 2020/0048365 W
|
Phytoextraction: Where’s the action?
|
Abstract Many articles concerning phytoextraction of trace elements state that it is “an emerging technology that can be used for the low-cost clean-up of contaminated land…”. Given the lack of commercial phytoextraction operations or even successful field trials, we sought to determine whether phytoextraction could ever compete with existing technologies to clean up soil within a realistic time-frame, say 10 are required to reduce the total metal concentration in soil by 50% within 25 years, under conditions that are ideal for phytoextraction. Heterogeneity of both the target element, nutrients, and water in soil, as well as heterogeneity of plant roots has a large, but as-yet unquantified effect on remediation time. Variations in climatic conditions, including drought and flooding can also reduce metal extraction rates. Unlike phytoextraction for soil cleansing, phytomining could theoretically produce valuable crops of metal. However, phytomining suffers from a low efficiency of metal extracted per unit of land. Ironically, phytomining may have a larger ecological footprint than conventional mining. Currently, lack of infrastructure limits its implementation. While our review shows that phytoextraction for soil cleansing and phytomining is currently impractical, it is not our intention to discourage research in this area. The best rebuttal of our analyses would be full-scale field operations. However, investigations of new plants/soils/soil conditioner combinations should at least demonstrate how phytoextraction could work by providing convincing basic mass-balance calculations.
|
publication
|
[
[
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Circular systems",
"Environmental observation"
]
] |
W1969760301
|
Towards improved understanding of the worldwide decline of wind speed in a climate change scenario
|
In a globally changing climate, scientists have paid little attention on variability of wind speed. A recent discovery to science is the “global stilling""; a worldwide slowdown of wind speed since the 1980s. This stilling is not fully understood and neither the quantity nor the quality of wind speed observations is adequate to allow a reliable study. The scientific aims of this MSCA to fill this key gap are (i) to rescue the longest wind speed series (starting prior to the 1960s), and (ii) to improve our knowledge on the influence of atmospheric circulation. Given the interdisciplinary impacts of ""global stilling"" on wind energy, agriculture and hydrology, the socioeconomic-environmental aim is (iii) to look at past wind speed to better assess future wind speed projections needed for climate change adaptation. The innovative approach combines the rescue (ACE framework) and homogenization (SNHT test) of historical wind speed data, providing a unique opportunity to statistically assess trends/cycles and atmospheric causes (SOM/RCPA and weather typing techniques) on long time periods and reliable datasets than previous studies. The applicant will bring his new homogenization protocol, extensive expertise on winds and a novel collaboration topic to UGOT and KNMI. In turn, these Institutions are world authorities on data rescue techniques and attributing causes of climate trends; the applicant will also be trained in leadership, management, funding, supervision and communication skills enhancing his career development. Jointly this team is in a position to push the boundaries of “global stilling” knowledge far ahead, with the ultimate intent to allow the applicant to train through research, establish an independent career, and a research group at the forefront of wind research in Europe. Additionally, this MSCA addresses two of the H2020 Societal Challenges: “Secure, Clean and Efficient Energy”, and “Climate action, Environment, Resource efficiency and Raw materials”.
|
project/european
|
[
[
"Climate, Energy and Mobility",
"Digital, Industry and Space",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Climate science and solutions",
"Energy supply"
]
] |
170503
|
Functional biology and ecology of planktonic marine fungi – revealing the mechanistic basis of the roles of mycoplankton in the marine carbon cycle
|
Marine planktonic fungi (mycoplankton) have been largely ignored compared to other plankton groups, such as phytoplankton, especially the roles that they fulfil in marine ecosystems. My research has shown that mycoplankton are a major structural and functional component of coastal ecosystems that have been almost completely overlooked. I have shown that mycoplankton are a substantial proportion of plankton biomass and that saprotrophic mycoplankton are active in coastal ecosystems. Mycoplankton are also a major plankton group in the open ocean and dominate on marine snow particles. These studies demonstrate that fungi have potential roles in the marine carbon cycle including the biological carbon pump. The absence of fungi within a general view of the structure and function of the marine carbon cycle, including a lack of mechanistic understanding of saprotroph functional biology and ecology, represent major knowledge gaps in our understanding of marine ecosystems that must urgently be addressed. MYCO-CARB will address these knowledge gaps through an innovative programme of research. Research cruises at established marine observatories will make an unprecedented assessment of active mycoplankton diversity and abundance across a range of ecosystems; from surface coastal waters to the deep open ocean. Innovative approaches, including molecular ecology tools and ecosystem modelling, will establish the impact of fungal saprotrophs on the marine carbon cycle. A culture collection will be developed, informed by the field-based surveys of natural assemblages to produce ecologically-relevant model fungi. Complementary culture-dependent and -independent systems biology methodologies will determine the underpinning biological machinery of saprotrophic marine mycoplankton. Through the MYCO-CARB research programme, I will open the marine fungal ‘black box’, revealing marine mycoplankton functional biology and ecology, and establishing their roles in the marine carbon cycle.
|
project/european
|
[
[
"Climate, Energy and Mobility",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Climate science and solutions",
"Energy systems and grids"
]
] |
222657
|
Chemical communication in the rhizosphere of plants
|
Plants secrete metabolites to communicate with other organisms in their rhizosphere. An exciting example of rhizosphere signalling molecules are the strigolactones. These are used by the friends of plants, the arbuscular mycorrhizal fungi, for host detection but also by their enemies, root parasitic plants. Furthermore, they have an endogenous signalling function, as a plant hormone that regulates shoot branching and root architecture. I postulate that this dual positive and negative signalling role of the strigolactones is the result of a paradigm: enemies of plants recruit molecules that are essential to the plant as cues. This paradigm has two important implications: 1) other plant-produced signalling molecules known to be abused by plant enemies likely have another, beneficial essential function in plants and 2) the involvement of multiple, positive and negative, biological functions exerts a selective pressure on these signalling molecules that results in the evolution of diversity in structure and biological specificity. In the project proposed here I will address implication 1) using an innovative approach in a new area by setting out to discover a new signalling role for plant parasitic cyst nematode hatching stimulants and I will investigate implication 2) by studying how biological specificity in strigolactones and hatching stimulants is mediated by the creation of structural diversity and the concomitant changes in perception, in parasitic plants and nematodes. This work will shed light on the significance of structural diversity in signalling molecules and the co-evolution of perception and may result in the discovery of a new class of signalling molecules in plants. It will also provide the fundamental knowledge enabling biotechnological and agronomical applications to optimise colonisation by AM fungi and plant development, and control parasitation by root parasitic plants and cyst nematodes.
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project/european
|
[
[
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Biodiversity and natural resources",
"Circular systems",
"Bio-based innovation systems in the bioeconomy",
"Agriculture, forestry and rural areas"
]
] |
172778
|
Chewing more than one can swallow: the creation of new districts in Uganda
|
As is the case in many other developing countries, Uganda’s decentralisation programme is designed to promote grassroots democracy and participatory development. However, it is argued in this paper that it is also meant to accommodate Uganda’s diverse identities and culture.
Uganda has undergone a process of decentralisation in which the district was chosen as the basic unit of local government to which powers and functions are devolved. Since the commencement of the decentralisation programme numerous new districts have been created.
After laying the ground for the constitutional articulation of districts as the main pillars of local governance, the article questions the practice of creating units of lower government that may not be economically sustainable. The article assesses what resources will be at the disposal of the districts and concludes that creating too many districts may disrupt the realisation of socio-economic rights. The process of creating new districts is not only open to manipulation, but also runs counter to the intended objectives of the decentralisation programme. The article makes a proposal for the establishment of an independent boundary demarcation body that should be responsible for changing district boundaries.
|
publication
|
[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations",
"Democracy and Governance",
"Culture, cultural heritage and creativity"
]
] |
W1999052260
|
GERENCIAMENTO DE STAKEHOLDERS E ESCRITÓRIO DE GERENCIAMENTO DE PROJETOS: EFEITO NOS RESULTADOS
|
RESUMO Uma vez que stakeholders de projetos afetam seus resultados, o gerenciamento desses atores deve ser considerado uma atividade relevante no gerenciamento de projetos. Somado a essa evidência, este estudo reconhece que os resultados de projetos podem ser incrementados quando há o apoio de um Escritório de Gerenciamento de Projetos (EGP). Assim, busca-se analisar a influência positiva do gerenciamento de stakeholders nos resultados dos projetos, especificamente na probabilidade de sua conclusão dentro de prazos e custos previstos, considerando o efeito moderador do apoio de EGPs. Para isso, o estudo apresenta um modelo conceitual validado por regressão logarítmica, usando dados coletados em pesquisa do tipo survey respondida por 216 professionais experientes da área de gerenciamento de projetos e que estudam o tema em cursos de pós-graduação. Os resultados indicam que o gerenciamento de stakeholders melhora os resultados de projetos e confirmam que o EGP aprimora a influência desse tipo de gerenciamento nos resultados. Como contribuição, a pesquisa reforça o gerenciamento de stakeholders e o apoio de EGPs como elementos-chave para o sucesso no gerenciamento de projetos. A amostragem foi suficiente para a replicabilidade da pesquisa, contudo restringiu-se a profissionais que vivem no Peru. Portanto, estudos futuros podem buscar alcançar uma população mais ampla.
|
publication
|
[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations"
]
] |
W4312534615
|
Modeling by Drawing with Shadow Guidance
|
Modeling 3D objects is difficult, especially for the user who lacks the knowledge on 3D geometry or even on 2D sketching. In this paper, we present a novel sketch-based modeling system which allows novice users to create 3D custom models by assembling parts based on a database of pre-segmented 3D models. Different from previous systems, our system supports the user with visualized and meaningful shadow guidance under his strokes dynamically to guide the user to convey his design concept easily and quickly. Our system interprets the user's strokes as similarity queries into database to generate the shadow image for guiding the user's further drawing and returns the 3D candidate parts for modeling simultaneously. Moreover, our system preserves the high-level structure in generated models based on prior knowledge pre-analyzed from the database, and allows the user to create custom parts with geometric variations. We demonstrate the applicability and effectiveness of our modeling system with human subjects and present various models designed using our system.
|
publication
|
[
[
"Culture, Creativity and Inclusive Society",
"Digital, Industry and Space"
]
] |
[
[
"Key digital technologies",
"Artificial intelligence and robotics",
"Advanced computing and big data"
]
] |
W2093227155
|
ROBUST EGR CONTROL FOR COUNTERACTING EXHAUST BACK-PRESSURE FLUCTUATION ATTRIBUTABLE TO SOOT ACCUMULATION IN A DIESEL PARTICULATE FILTER
|
An engine (10) uses a method for counteracting the effect of soot accumulation in a diesel particulate filter (DPF 38) in a diesel engine exhaust system (16) on the control of exhaust gas recirculation (EGR) through an EGR system (40). Engine speed (N) and indicated engine torque (TQI) data are processed to select from a map (62) a data value for present EGR volumetric efficiency. The selected data value and certain other data, including data that accounts for present soot accumulation in the DPF, are processed to develop a data value indicative of present total mass flow. The data value indicative of present total mass flow and still other data are processed to develop flow control data for controlling flow of exhaust gas through the EGR system.
|
patent
|
[
[
"Climate, Energy and Mobility",
"Digital, Industry and Space"
]
] |
[
[
"Clean, safe and accessible transport and mobility",
"Industrial competitiveness in transport",
"Energy supply",
"Energy systems and grids"
]
] |
US 2005/0043451 W
|
DOMESTIC CLOTHS
|
The invention relates to a domestic cloth for cleaning surfaces. The domestic cloth according to the invention is to be understood as a cleaning cloth, with which surfaces in the home or in the field of gastronomy can be cleaned, and such a cloth is provided with which surfaces in the kitchen area can be cleaned. The problem addressed by the invention is that not just aqueous liquids but also lipid liquids, i.e. oils and grease, are to be absorbed. The invention solves this problem by providing a domestic cloth for cleaning surfaces, consisting of at least three nonwoven fabrics which are arranged one over the other and which are made of reinforced fibers, wherein two outer nonwoven fabrics have a mass per surface unit which is greater than the mass per surface unit of a central nonwoven fabric arranged between the two outer nonwoven fabrics.
|
patent
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Manufacturing technologies"
]
] |
EP 2015081039 W
|
Effect of exercise test on pulmonary function of obese adolescents
|
to investigate the pulmonary response to exercise of non-morbidly obese adolescents, considering the gender.a prospective cross-sectional study was conducted with 92 adolescents (47 obese and 45 eutrophic), divided in four groups according to obesity and gender. Anthropometric parameters, pulmonary function (spirometry and oxygen saturation [SatO2]), heart rate (HR), blood pressure (BP), respiratory rate (RR), and respiratory muscle strength were measured. Pulmonary function parameters were measured before, during, and after the exercise test.BP and HR were higher in obese individuals during the exercise test (p = 0.0001). SatO2 values decreased during exercise in obese adolescents (p = 0.0001). Obese males had higher levels of maximum inspiratory and expiratory pressures (p = 0.0002) when compared to obese and eutrophic females. Obese males showed lower values of maximum voluntary ventilation, forced vital capacity, and forced expiratory volume in the first second when compared to eutrophic males, before and after exercise (p = 0.0005). Obese females had greater inspiratory capacity compared to eutrophic females (p = 0.0001). Expiratory reserve volume was lower in obese subjects when compared to controls (p ≤ 0,05).obese adolescents presented changes in pulmonary function at rest and these changes remained present during exercise. The spirometric and cardiorespiratory values were different in the four study groups. The present data demonstrated that, in spite of differences in lung growth, the model of fat distribution alters pulmonary function differently in obese female and male adolescents.
|
publication
|
[
[
"Health",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Health throughout the life course",
"Non-communicable and rare diseases"
]
] |
W1969609222
|
um alojamento de conector com um elemento de travamento de contato compreendendo um elemento de engatamento
|
resumo patente de invenção: "um alojamento de conector com um elemento de travamento de contato compreendendo um elemento de engatamento". a invenção refere-se a um alojamento de conector (1) com um corpo de alojamento (2) e pelo menos um elemento de travamento (3) para prender elementos de contato. a fim de ser capaz de engatar o elemento de travamento (3) na sua posição de fixação (p) com uma força constante, a invenção permite que pelo menos um elemento de engatamento (12) seja arranjado em um lado do elemento de travamento (3) que está voltado para longe de uma extremidade fixa (29) do elemento de travamento (3).
|
patent
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Manufacturing technologies"
]
] |
BR 112014017461 A
|
Functional diversity of t cells
|
T cells have a central role in most adaptive immune responses, including immunity to infection, cancer, and autoimmunity. Increasing evidence shows that even resting steady-state T cells form many different subsets with unique functions. Variable level of self-reactivity and previous antigenic exposure are most likely two major determinants of the T-cell diversity. However, the number, identity, and biological function of steady-state T-cell subsets are still very incompletely understood. Receptors to ligands from TNF and B7 families exhibit variable expression among T-cell subsets and are important regulators of T-cell fate decisions. We hypothesize that pathways triggered by these receptors substantially contribute to the functional diversity of T cells.The FunDiT project uses a set of novel tools to systematically identify steady-state CD8+ T cell subsets and characterize their biological roles. The project has three complementary objectives.
(1) Identification of CD8+ T cell subsets. We will identify subsets based on single cell gene expression profiling. We will determine the role of self and foreign antigens in the formation of these subsets and match corresponding subsets between mice and humans.
(2) Role of particular subsets in the immune response. We will compare antigenic responses of particular subsets using our novel model allowing inducible expression of a defined TCR. The activity of T-cell subsets in three disease models (infection, cancer, autoimmunity) will be characterized.
(3) Characterization of key costimulatory/inhibitory pathways. We will use our novel mass spectrometry-based approach to identify receptors and signaling molecules involved in the signaling by ligands from TNF and B7 families in T cells.
The results will provide understanding of the adaptive immunity in particular disease context and resolve long-standing questions concerning the roles of T-cell diversity in protective immunity and tolerance to healthy tissues and tumors.
|
project/european
|
[
[
"Health"
]
] |
[
[
"Non-communicable and rare diseases",
"Healthcare systems",
"Tools, technologies and digital solutions for health and care, including personalised medicine",
"Infectious diseases, including poverty-related and neglected diseases"
]
] |
889949
|
Efectos de las dinámicas del ingreso laboral departamental sobre el acceso al Sistema Privado de Administración De Pensiones
|
Objetivo: Determinar el efecto que tiene la dinámica de los ingresos laborales a nivel departamental en el Perú sobre la afiliación al Sistema Privado de Administración de Pensiones (SPP), en el periodo 2004-2021. Método: Se utilizó un modelo de datos de panel con efectos fijos para estimar el efecto que tiene la dinámica de los ingresos laborales durante el periodo 2004-2021, entendido como la proporción de la Población Económicamente Activa Ocupada (PEAO) que tiene ingresos laborales dependientes por encima de la Remuneración Mínima Vital (RMV), sobre un indicador de acceso como la afiliación al SPP referido al porcentaje de la PEAO que se encuentra afiliado a dicho sistema. Resultados: Se observa que existe una dinámica diferenciada tanto en el ritmo de afiliación al SPP como en el crecimiento del ingreso laboral, y el ingreso laboral dependiente entre los departamentos. Asimismo, se determinó un efecto positivo y estadísticamente significativo de la proporción de la PEAO que cuenta con ingresos laborales dependientes por encima de la RMV sobre el porcentaje de afiliación al SPP. Conclusión: Los departamentos cuya población cuenta con mayor proporción de ingresos laborales dependientes por encima de la RMV tienen mayor acceso al SPP, entendido como un nivel más alto de afiliación como parte de la PEAO.
|
publication
|
[
[
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[]
] |
W4284899717
|
Study of Acid Treated Mixed Sawdust as Natural Oil Sorbent for Oil Spill
|
Abstract Despite the presence of many techniques to clean up oil spills, sorbents are considered as one of the most attractive techniques due to the high rate of absorption or adsorption and ease of application. Organic-based sorbents have become the best type to use based on their abundance of resources and its biodegradability. Among the many natural organic sorbents available, sawdust has big potential to be used as oil absorbent due to its advantages of being low-cost source, low density and exhibiting hydrophobic-oleophillic characteristics. In this study, the utilization of mixed sawdust as oil sorbent was investigated. The mixed sawdust sorbent was treated using chemicals such as ethanol, sodium hydroxide and hydrochloric acid to further improve the efficiency for oil absorbency. The performance of as-prepared and acid-treated sorbent was characterized using sorption capacity (g/g). The effects of sorption time and surface condition (on seawater surface or on land) towards the performance of sorbent was then investigated. Besides that, the temperature, oil viscosities and reusability of treated sawdust were also studied. It has been proven that acid treated sawdust has higher sorption capacity of 4.82 g/g even after 90 minutes of sorption with four times reusability due to improved hydrophobic and oleophillic characteristics. It was also found that the viscosity of oil and temperature can also affect the sorption capacity. Crude oil, which poses lower viscosity (30.51cP) and at oil temperature of 27°C gave the highest sorption because of the migration of oil into the structure of sorbent was accelerated. This study indicated the possibility of using sawdust as sorbent for oil spill control.
|
publication
|
[
[
"Climate, Energy and Mobility",
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Energy supply"
]
] |
W3000711650
|
Building multi‐level governance in Southeast Europe?
|
Drawing on the contributions to this volume, this concluding analysis reflects on the extent to which European Union (EU) cohesion policy and related pre‐accession instruments are contributing to the development of more compound polities in Southeast Europe and, specifically, promoting multi‐level governance. It argues that these EU policies have created more compound polities but that system‐wide multi‐level governance remains weak in the case study states and central governments remain prominent. However, there are interesting and potentially important developments in relation to particular features of multi‐level governance, not least in states whose engagement with the EU in this sphere is relatively new. As such, a large part of this story appears yet to unfold.
|
publication
|
[
[]
] |
[
[]
] |
W2009648726
|
Le Fecho del Imperio, Alphonse X le Sage et l’Empire
|
ESPAÑA EN EUROPAEn 1998 se conmemoró el centenario de la crisis del 98. Al rememorar esta efemérides, hablamos del que ha sido y es uno de los puntos de referencia de nuestra Historia.Las ambigüedades y contradicciones de un sistema económico y social en vías de expansión universal que recibe los honores de quienes creen en el progreso indefinido y las críticas de los que intuyen su injusticia latente se manifiestan en el caso español con las peculiaridades propias de un momento que contempla la pérdida de sus últimas colonias.En los primeros lustros del siglo XX, una serie de políticos, intelectuales y científicos denunciaron los males de la situación y clamaron por la regeneración de la vida española, traducida en nuestra europeización e integración en la cultura occidental.Sin embargo, los anhelos de los noventayochistas no vendrán a colmarse hasta 1985, año en el que el Reino de España, como fruto a un dilatado período de negociaciones, suscribe el Tratado de Adhesión a las Comunidades europeas en solemne acto celebrado en el Palacio Real de Madrid.En realidad, este paso supuso la culminación de un vetusto proyecto En el siglo IX, Carlomagno instaura el Imperio carolingio, heredero del antiguo Imperio Romano de Occidente, marcando de esta manera el nacimiento político de Europa.Será a mediados del siglo XIX cuando se comience a gestar la idea de la integración de varias naciones con una cultura, un pasado común y una proximidad geográfica, pero no es hasta el siglo XX cuando, tras la estela de destrucción que dejan las dos Guerras Mundiales, se materializan los primeros logros y se establecen las primeras constituciones o foros de cooperación política (Consejo de Europa, BENELUX, CECA).El Tratado de Maastricht adoptó en 1992 diversas medidas tendentes a frenar el monopolio comercial americano y asiático, labor a la que contribuyeron eficazmente los Presidentes
|
publication
|
[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Democracy and Governance",
"Culture, cultural heritage and creativity"
]
] |
W4226078744
|
Comparing the copperbelt: political culture and knowledge production in central africa
|
This project provides the first comparative historical analysis – local, national and transnational - of the Central African copperbelt. This globally strategic mineral region is central to the history of two nation-states (Zambia and Democratic Republic of Congo (DRC)), as well as wider debates about the role of mineral wealth in development. The project has three interrelated and comparative objectives. First, it will examine the copperbelt as a single region divided by a (post-)colonial border, across which flowed minerals, peoples, and ideas about the relationship between them. Political economy created the circumstances in which distinct political cultures of mining communities developed, but this also involved a process of imagination, drawing on ‘modern’ notions such as national development, but also morally framed ideas about the societies and land from which minerals are extracted. The project will explain the relationship between minerals and African polities, economies, societies and ideas. Second, it will analyse how ‘top-down’ knowledge production processes of Anglo-American and Belgian academies shaped understanding of these societies. Explaining how social scientists imagined and constructed copperbelt society will enable a new understanding of the relationship between mining societies and academic knowledge production. Third, it will explore the interaction between these intellectual constructions and the copperbelt’s political culture, exploring the interchange between academic and popular perceptions. This project will investigate the hypothesis that the resultant understanding of this region is the result of a long unequal interaction of definition and determination between western observers and African participants that has only a partial relationship to the reality of mineral extraction, filtered as it has been through successive sedimentations of imagining and representation laid down over nearly a century of urban life in central Africa.
|
project/european
|
[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations",
"Democracy and Governance",
"Culture, cultural heritage and creativity"
]
] |
185390
|
PUblic authorities Role Enhancing COmpetitiveness of SMeS
|
PURE COSMOS brings together two of the big challenges facing the EU: the need to stimulate and support SMEs and the need to reduce the weight of public administration.
So PURE COSMOS aims to improve the effectiveness of public support for SMEs by 15%, cutting costs by 10% and improving quality by 20%. We will develop highly integrated approaches to deliver these improvements and we will especially target entrepreneurs aged 25-40.
We will improve regional policies through innovative new projects and by improving governance so that the different stakeholders can agree common solutions. We will do this by:
* analysing partners’ plans through peer review,
* identifying good practices that will improve these plans, studying them through Study Visits, importing them via special workshops and Regional Action Plans.
We will closely involve SMEs in the work.
The project’s main outputs will benefit SMEs, especially young entrepreneurs. They are:
* New projects to implement advanced services such as e-payments tools, One Stop Shop, “digital by default” models, digital-skills support.
* Improved governance through IT administrative solutions, regional legislation review, simplifying and speed up the launching of new businesses calls.
All Action Plans will be prepared using intense cooperation between the key decision-makers (horizontal cooperation) and between the city and the MAs (vertical cooperation). The project will also work closely with the IE Policy Learning Platform.
|
project/regional
|
[
[
"Culture, Creativity and Inclusive Society",
"Digital, Industry and Space"
]
] |
[
[
"Key digital technologies",
"Circular systems"
]
] |
interreg_2809
|
Euro-Mediterranean Network Facilitating Market Uptake of Innovations from SMEs
|
EMPHASIS is set on co-creating a Mediterranean Open Innovation (OI) ecosystem, in which knowledge flows across borders and is translated into marketable innovations. The project will co-design, deploy and validate a Mediterranean OI service platform, aiming at better linking the fragmented innovation systems of the region by facilitating meaningful cross-border knowledge flows, empower SMEs with the skill-sets required to tap into external knowledge base and turn it into value and identify fields that can turn sustainability challenges (e.g., agri-food, energy, materials) into business opportunities. EMPHASIS will lead to the uptake of the results from a series of projects to identify SMEs, assess their ‘readiness’ to engage with OI and provide them advisory services - in the form of vouchers – to enhance their innovation capacity to build partnerships, covering the different stages of their innovation journeys. A joint transnational approach will be a solid action to address the sustainability agendas through effective market uptake of research outputs.
|
project/regional
|
[
[
"Culture, Creativity and Inclusive Society",
"Digital, Industry and Space"
]
] |
[
[
"Emerging enabling technologies",
"Circular systems"
]
] |
interreg_1160
|
Xinfeng capsule improves pulmonary function in ankylosing spondylitis patients via NF-κB-iNOS-NO signaling pathway
|
To study changes in the nuclear factor-κB p65 (NF-κB p65)-inducible nitric oxide synthase (iNOS)-nitric oxide (NO) signaling pathway and the effects of Xinfeng capsules (XFC) in patients with ankylosing spondylitis (AS).One hundred twenty patients with AS were randomly divided into an XFC group and a Salazopyrin group. Sixty health subjects were included as a normal control group. In the two treatment groups, pulmonary functional parameters, forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), maximal voluntary ventilation (MVV), peak expiratory flow (PEF), forced expiratory flow at 25% of forced vital capacity (FEF25), forced expiratory flow at 50% of forced vital capacity (FEF50), and forced expiratory flow at 75% of forced vital capacity (FEF75) were determined. Enzyme linked immunosorbent assays were used for detection of the serum oxidative stress indexes, NF-κB p65, iNOS, NO, reactive oxygen species (ROS), reactive nitrogen species (RNS), malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), total antioxidative capacity (TAOC) and interleukin-4 (IL-4), IL-10, IL-1β, and tumor necrosis factor-α (TNF-α) contents. Westergren's method was used for determination of erythrocyte sedimentation rate (ESR). High-sensitivity C-reactive protein (Hs-CRP) was detected with a 7060 full-automatic biochemical analyzer (Hitachi, Japan).The clinical therapeutic effect in the XFC group was significantly superior to that in the Salazopyrin group (P < 0.01). Compared with the normal control group, FEV1, MVV, PEF, FEF50, FEF75, SOD, CAT, TAOC, IL-4, IL-10 were significantly lower, and NF-κB p65, iNOS, NO, ROS, RNS, MDA, IL-1β, TNF-α, ESR, and Hs-CRP significantly higher in patients with AS (P < 0.01 or P < 0.05). Compared with before treatment, FEV1, MVV, PEF, FEF50, FEF75, SOD, CAT, TAOC, IL-4, and IL-10 were significantly increased, and NF-κB p65, iNOS, NO, ROS, RNS, MDA, IL-1β, TNF-α, ESR, CRP, visual analog scales (VAS), Bath ankylosing spondylitis disease active index, Bath ankylosing spondylitis functional index, and Bath ankylosing spondylitis global index significantly decreased in the two treatment groups after treatment (P <. 0.01 or P < 0.05), with significant differences between the XFC and Salazopyrin groups (P < 0.01 or P < 0.05). Spearman correlation analysis indicated that FEV1, MWVV, PEF, FEF50, and FEF75 were positively correlated with SOD, CAT, TAOC, IL-4, and IL-10, and were negatively correlated with NF-κB p65, iNOS, NO, ROS, RNS, MDA, IL-13, TNF-α, ESR, and CRP.Patients with AS have local pathologic changes in the spinal cord and other joints. They also have decreased pulmonary function, which is negatively correlated with the NF-κB-iNOS-NO signaling pathway, oxidative indexes, and inflammatory factors. XFC improves rigidity and pain in spinal joints and other symptoms, laboratory indexes, and pulmonary function. The mechanism is possibly related to inhibition of the NF-KB-iNOS-NO signaling pathway.
|
publication
|
[
[
"Health"
]
] |
[
[
"Non-communicable and rare diseases"
]
] |
W305361774
|
Effect of long-term surface temperature variation on fault displacement observation and anomalous fault movement in Western Sichuan before the Lushan M_s7.0 earthquake
|
About 2—3 years before the Lushan Ms7.0 earthquake on 20 April 2013,some shortbaseline and short-leveling sites in western Sichuan presented long-term and quasi-synchronous trend transition.However,the temperatures from some auxiliary observation were similar to fault displacements in some extent.So,in order to explore if they are thermal deformation,we analyze the short-baseline,short-leveling,and temperature observation data from Xianshuihe,Anninghe-Zemuhe,and Longmenshan fault zone.Based on spectrum and statistical analysis methods,the correlation between fault displacement and temperature is studied.Furthermore,the movement features of these fault zones are discussed by using principal mode analysis.The results show that:(1) In the period of larger than 2.63 years,the fault displacement and temperature data have similar frequency components,and have weak to moderate correlation.(2)The variation of temperature is not the major influence factor on the trend transition of fault displacement before Lushan earthquake.Except individual site,the secular thermal deformation only contributes a small fraction in the whole deformation.(3) The principal mode analysis suggests that,around 2010,the left-lateral strike slip and tensional movement weakened along Xianshuihe fault zone,and the tensile motion of Anninghe-Zemuhe and Longmenshan fault zone weakened also.These variation features may be associated with the intensive movement in SESEE orientation of the Bayan Har tectonic block in this stage.
|
publication
|
[
[
"Civil Security for Society"
]
] |
[
[
"Protection and security",
"Disaster-resilient societies"
]
] |
W2389783731
|
Social wearable sensors to support engagement and learning in children with autism + learning difficulties.
|
Children with autism and learning difficulties often need substantial support in schools and in later life with communication, emotion regulation and daily living skills. Teaching these children and measuring their progress in education is challenging. Our recent work (ERC grant INTERACT 313398) showed that tracking body motion in children and adults can give a real-world measure of how much people are engaged in a social interaction. In this project, we develop this result into a wearable sensor system to quantify and support children’s learning. In the SocSensor system, each child and teacher wears a sensor on their wrist (like a FitBit) and we track how they move in relation to each other, that is, their social engagement. This continuous monitoring is unobtrusive and is particularly valuable in understanding the behaviour of children with minimal verbal skills who cannot easily express themselves. Teachers and/or researchers can receive a report at the end of the lesson showing how often children were engaged and who interacted with who, which will allow them to monitor the effectiveness of lessons and compare different educational approaches. This will allow them to optimise learning opportunities for these-hard-to-reach children. The domains of educational technology and wearables are growing rapidly but no other product addresses the needs of children with autism and learning difficulties, so the SocSensors system can make a big impact.
In this project, we will develop the interface for the SocSensors sensor system, collect validation data in a large autism school and build connections with business partners. This will move SocSensors from a lab prototype to a viable product, as well as showcasing the product to schools, teachers and the autism community. Thus, SocSensors will lead the way in using psychology and wearable computing to support engagement and learning in children with autism + learning difficulties.
|
project/european
|
[
[
"Culture, Creativity and Inclusive Society",
"Digital, Industry and Space"
]
] |
[
[
"Key digital technologies",
"Artificial intelligence and robotics",
"Emerging enabling technologies",
"Advanced computing and big data"
]
] |
3725683
|
Short-day and melatonin effects on milking parameters, prolactin profiles and growth-hormone secretion in lactating sheep
|
Abstract We tested the hypothesis that elevated levels of melatonin in lactating sheep, simulated either by short-day conditions or by melatonin implants, would decrease milk yield while disturbing the rhythm of prolactin (PRL) and growth-hormone (GH) secretion. Eight weeks after lambing, lambs were weaned, and the ewes were subsequently used for milking. The ewes were divided into three groups: (i) long-day control group (LDC, n = 20); (ii) long-day melatonin-treated group (LDM, n = 20) and (iii) artificial short-day group (ASD, n = 20). Milk yields were recorded individually at 10-day intervals from day 57 of lactation. Blood samples were drawn from the sheep every 28 days to monitor the changes in PRL and GH secretion. On each sampling date, blood samples were collected at 20-min intervals over a 6-h period beginning at 12:00 p.m. The plasma concentrations of PRL and GH were measured using radioimmunoassay. The longest duration of lactation was found in LDC sheep, and the shortest duration was found in LDM and ASD sheep ( p p ≤ 0.01) less milk was obtained from the ASD group. The highest PRL concentration was found during the long-day period (from May to July) in LDC sheep. Prolactin concentration decreased with increasing duration of lactation and decreasing day length. The use of melatonin implants (LDM group) or artificial short-day conditions (ASD group) significantly ( p ≤ 0.01) decreased PRL secretion and reduced milk yield as early as the beginning of milking. Growth-hormone concentrations were significantly ( p ≤ 0.001) higher in LDC ewes than in LDM and ASD ewes. In contrast to the temporal profile of PRL secretion, GH concentrations decreased during the long-day period but increased as lactation progressed and day length shortened. Despite the considerable reduction in GH concentrations, the GH-secretion profile retained its characteristic seasonal rhythm. Therefore, we conclude that exogenous melatonin (from implants or induced by artificial photoperiod manipulation) decreases milk yield primarily through its effect on PRL concentrations in lactating ewes.
|
publication
|
[
[
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Agriculture, forestry and rural areas",
"Food systems",
"Bio-based innovation systems in the bioeconomy"
]
] |
W1970081024
|
Origen, evolución y caída del régimen de Mubarak
|
This paper describes in political, sociological and economic terms the origin and evolution of Mubarak’s regime till its fall, including Mohamed Mursi’s election as president of Egypt. First, it places Mubarak’s period in power in its historical context, following Naser and Sadat’s regimes. Then it describes the interaction between the new regime’s economic and political proposals and the political and parapolitical responses on the part of Egyptian society. Finally it shows how the relative stability of the regime, lasting over twenty years and built on a combination of coercion and selective permissiveness, began to collapse, partly as a result of the effects of the economic liberalisation started in the 1990s on
|
publication
|
[
[
"Culture, Creativity and Inclusive Society"
]
] |
[
[
"Social and economic transformations",
"Democracy and Governance"
]
] |
W1560073854
|
SYSTEM AND METHOD OF CONTROLLING COMPRESSOR
|
A compressor control system includes a compressor compressing a fluid, an anti-surge valve preventing backflow in the compressor, the anti-surge valve being arranged on a line connecting an inlet and an outlet of the compressor and operated by a first signal, an inlet guide vane controlling an opening area of the inlet, the inlet guide vane being arranged at the inlet and operated by a second signal, and a controller connected to the anti-surge valve and the inlet guide vane and generating the first signal to control the anti-surge valve, a vane control signal to control the inlet guide vane, a pressure compensation signal to control the inlet guide vane to compensate for a change in pressure at the outlet of the compressor according to the first signal, and the second signal by combining the pressure compensation signal with the vane control signal.
|
patent
|
[
[
"Digital, Industry and Space"
]
] |
[
[
"Manufacturing technologies"
]
] |
US 201715451697 A
|
Forest Fires Effects on Carbon Stocks and Soil Chemistry in Central Yakutia, Eastern Siberia
|
This study was conducted to determine the impact of fire on the physical and chemical characteristics of soil as well as on the distribution of soil organic and black carbon stocks in ice-rich permafrost regions in eastern Siberia. Three intact and four burnt forest sites with different ignition years were selected. Volumetric water content did not increase in any of the burnt forests in the top soil layer but moisture accumulated at the bottom of the active layer of older burnt sites. Salt content increased in the active layer following forest fires, but a decade later, the salt increase disappeared, indicating the temporal characteristic of this change. The concentration of Na + and SO4 2- in the active layer of the 4-year-old burnt forest site increased 70% and 49% respectively, while other salts (Mg 2+ and Ca 2+ ) did not show any variation in the other burnt forest sites compared to the intact forest sites. The organic carbon stock in the top 200 cm of soil in the intact forest site (44.0 kg m -2 ) was similar to that in burnt forest sites (41.4-43.7 kg m -2 ). On average, 37% of organic carbon was found in the upper 30 cm of the soil profile for intact and burnt forests. The organic carbon distribution in the top 200 cm soil layer in Central Yakutia was higher than previously reported for other Siberian sites. The highest concentrations of black carbon were found in the upper soil layers (20-40 mg g -1 organic carbon) but concentrations of 10-20 mg g -1 organic carbon were also found in the permafrost (120-200 cm depth) of the intact and burnt forests. There was no variation in black carbon concentration among the sites. The presence of black carbon in the permafrost suggests that the active layer was deeper before and that black carbon accumulated because of fires that occurred at that time.
|
publication
|
[
[
"Food, Bioeconomy, Natural Resources, Agriculture and Environment"
]
] |
[
[
"Seas, oceans and inland waters",
"Biodiversity and natural resources",
"Agriculture, forestry and rural areas",
"Circular systems",
"Environmental observation"
]
] |
W9706250
|
Uwb wearable apparatus for bone fracture imaging and recovering monitoring
|
Global changes in healthcare funding, an increasingly ageing demographic, explosions of new technologies are converging to transform our relationship with healthcare. Breakthrough innovations formed outside traditional healthcare industries are needed to change business models, reshape the future for better health outcomes and value for consumer. Thus, research on novel diagnostic and monitoring imaging modalities is essential.
UWB imaging has recently emerged as one of the most promising non-invasive imaging modalities of the last two decades. Its low cost, non-ionising characteristics justify the considerable interest of the scientific community. Extension of microwave imaging to bone fracture assessment is one goal of WEBOING proposal. In this contest, the design of UWB wearable apparatus for bone fracture imaging and recovering monitoring will allow to perform imaging without exposing patients to dangerous X-rays.
The portable nature of the apparatus, will allows its use in site of accidents. In fact, simple microwave antennas coupled with a laptop-integrated Vector Network Analyser (VNA) are required, giving the methodology simplicity in manufacturing and a very a low cost; this aspect is even more significant if related to conventional techniques. Imaging of the bone fracture will be performed for the first time by appropriately reconstructing the electromagnetic field at UWB frequencies. Electromagnetic field reconstruction will be performed combining Modes concept and Huygens principle, which represents a new and unconventional procedure. Moreover, the same UWB antennas will also allow fracture recovering monitoring; in fact, by embedding the antennas in the plaster cast, it will be possible to perform bone imaging on periodic base without having to remove the plaster cast itself. Since the apparatus will use safe UWB rather that dangerous non-ionising radiation, examination can be repeated any time and in any condition.
|
project/european
|
[
[
"Health",
"Digital, Industry and Space"
]
] |
[
[
"Healthcare systems",
"Environmental and social health determinants",
"Tools, technologies and digital solutions for health and care, including personalised medicine"
]
] |
224668
|
End of preview. Expand
in Data Studio
ESPON Annotated Scientific Publications Dataset
This dataset consists of annotated scientific publications with the following fields:
id: Unique identifier for the recordtitle: Title of the publicationabstract: Abstract of the publicationcluster_responses: List of cluster annotations (may be empty in test)area_responses: List of area of intervention annotations (may be empty in test)
Splits
- Train: Contains full annotations for all fields (
cluster,area, and possibly others) - Test: Contains labels only for
clusterandarea of intervention
Category Names
Cluster Labels (6 unique):
- Civil Security for Society
- Climate, Energy and Mobility
- Culture, Creativity and Inclusive Society
- Digital, Industry and Space
- Food, Bioeconomy, Natural Resources, Agriculture and Environment
- Health
Area of Intervention Labels (38 unique):
- Advanced Materials
- Advanced computing and big data
- Agriculture, forestry and rural areas
- Artificial intelligence and robotics
- Bio-based innovation systems in the bioeconomy
- Biodiversity and natural resources
- Buildings and industrial facilities in energy transition
- Circular Industries
- Circular systems
- Clean, safe and accessible transport and mobility
- Climate science and solutions
- Communities and cities
- Culture, cultural heritage and creativity
- Cybersecurity
- Democracy and Governance
- Disaster-resilient societies
- Emerging enabling technologies
- Energy storage
- Energy supply
- Energy systems and grids
- Environmental and social health determinants
- Environmental observation
- Food systems
- Healthcare systems
- Health throughout the life course
- Infectious diseases, including poverty-related and neglected diseases
- Industrial competitiveness in transport
- Key digital technologies
- Manufacturing technologies
- Net-zero and less polluting Industries
- Next generation internet
- Non-communicable and rare diseases
- Protection and security
- Seas, oceans and inland waters
- Smart mobility
- Social and economic transformations
- Space, including Earth observation
- Tools, technologies and digital solutions for health and care, including personalised medicine
Annotation Methodology
The training data was annotated using an ensemble of large language models.
Specifically:
- Initial predictions were generated independently by:
Meta-Llama-3.1-8B-Instructdeepseek-ai/DeepSeek-R1-Distill-Llama-70B
- For each item, the final label was determined by majority vote among these models.
- In cases where there was no majority (i.e., a tie), a tie-breaker model (
microsoft/WizardLM-2-8x22B) was used to select the final label.
This approach aims to increase annotation reliability by leveraging multiple state-of-the-art models and resolving uncertainty with a strong tie-breaker model.
Number of Samples
| Split | Number of samples |
|---|---|
| Train | 7,647 |
| Test | 229 |
Usage
from datasets import load_dataset
dataset = load_dataset('nicolauduran45/horizon_clusters_annotated')
- Downloads last month
- 109
Size of downloaded dataset files:
7.02 MB
Size of the auto-converted Parquet files:
7.02 MB
Number of rows:
7,876